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Sample records for bright gm mendoza

  1. Mendoza : Rahvuslike huvide eiramine toob Euroliidule kollapsi / Alan Mendoza ; interv. Indrek Veiserik

    Index Scriptorium Estoniae

    Mendoza, Alan

    2008-01-01

    Intervjuu Henry Jacksoni Ühingu presidendiga, kes vastab küsimustele, mis puudutavad NATO laienemist, Lissaboni lepet, Euroopa Liidu kaitse- ja välispoliitikat, Eesti välispoliitikat ja suhteid Venemaaga. Vt. samas: Alan Mendoza ja Henry Jacksoni ühing

  2. Payenia volcanic province, southern Mendoza, Argentina

    DEFF Research Database (Denmark)

    Søager, Nina; Holm, Paul Martin; Llambias, Eduardo Jorge

    2013-01-01

    The Pleistocene to Holocene Payenia volcanic province is a backarc region of 60,000 km2 in Mendoza, Argentina, which is dominated by transitional to alkaline basalts and trachybasalts. We present major and trace element compositions of 139 rocks from this area of which the majority are basaltic...... basalts, trace element variations suggest a significant contribution from lower crustal melts, possibly up to 70% in the most extreme cases. The contaminating lower crustal rocks must have been depleted mafic rocks with a plagioclase component. The extensive melting of lower crust is probably related...

  3. GM Risk Assessment

    Science.gov (United States)

    Sparrow, Penny A. C.

    GM risk assessments play an important role in the decision-making process surrounding the regulation, notification and permission to handle Genetically Modified Organisms (GMOs). Ultimately the role of a GM risk assessment will be to ensure the safe handling and containment of the GMO; and to assess any potential impacts on the environment and human health. A risk assessment should answer all ‘what if’ scenarios, based on scientific evidence.

  4. Improvement on GM models

    Institute of Scientific and Technical Information of China (English)

    党耀国; 刘思峰; 刘斌

    2004-01-01

    Since grey system theory was established by prof. Deng, GM models and their improvements have all taken the first vector of the original sequence as the initialization, which resulted to deficiency in making use of the latest infor-mation. Based on the principle, which new information should be used fully, we think it is scientific to pay more atten-tion to the new information or endow them a more weigh. So, this paper deals with the GM improvement by taking the n-th vector as the initialization, and gets great improvement in forecasting precision. Last, we validate the practicability and reliability of the moelds with examples.

  5. The Unusual Photometric Variability of the PMS Star GM Cep

    Science.gov (United States)

    Semkov, E. H.; Ibryamov, S. I.; Peneva, S. P.; Milanov, T. R.; Stoyanov, K. A.; Stateva, I. K.; Kjurkchieva, D. P.; Dimitrov, D. P.; Radeva, V. S.

    2015-03-01

    Results from UBVRI photometric observations of the pre-main sequence star GM Cep obtained in the period 2011 April-2014 August are reported in the paper. Presented data are a continuation of our photometric monitoring of the star started in 2008. GM Cep is located in the field of the young open cluster Trumpler 37 and over the past years it has been an object of intense photometric and spectral studies. The star shows a strong photometric variability interpreted as a possible outburst from EXor type in previous studies. Our photometric data for a period of over six years show a large amplitude variability (ΔV ~ 2.3 mag) and several deep minimums in brightness are observed. The analysis of the collected multicolour photometric data show the typical of UX Ori variables a colour reversal during the minimums in brightness. The observed decreases in brightness have a different shape, and evidences of periodicity are not detected. At the same time, high amplitude rapid variations in brightness typical for the classical T Tauri stars also present on the light curve of GM Cep. The spectrum of GM Cep shows the typical of classical T Tauri stars wide Hα emission line and absorption lines of some metals. We calculate the outer radius of the Hα emitting region as 10.4 ± 0.5 R⊙ and the accretion rate as 1.8 × 10- 7 M⊙ yr- 1.

  6. A NEGATIVE ANSWER TO A PROBLEM OF FREMLIN AND MENDOZA

    Institute of Scientific and Technical Information of China (English)

    Ye Guoju; Stefan Schwabik

    2007-01-01

    This article studies some convergence results for the McShane integral of functions mapping the interval [0, 1] into a Banach space X from the point of view of an open problem proposed by D.H.Fremlin and J. Mendoza in [2], also the anthors give a negative answer to this open problem.

  7. El volcanismo del Terciario superior del sur de Mendoza Upper Terciary volcanism from southern Mendoza

    Directory of Open Access Journals (Sweden)

    F. E. Nullo

    2002-06-01

    Full Text Available Se describe por primera vez la petrografía y geoquímica de unidades volcánicas terciarias del sur de la provincia de Mendoza. Se analizan la nomenclatura estratigráfica y sus edades, estableciéndose una secuencia de eventos magmáticos ocurridos durante el Neógeno, comenzando con la evolución de un retro-arco, seguido por un arco magmático más joven. Se intenta respetar la nomenclatura estratigráfica existente, sin embargo, la definición de unidades se ha realizado sobre la base de las edades radimétricas y sus edades de cristalización, más sobre sus características petrográficas. La actividad magmática se extiende desde el Oligoceno superior al Mioceno superior, correspondiendo a el Ciclo Eruptivo Molle y el Ciclo Eruptivo Huincán, y comenzó con un episodio magmático basáltico inicial (CEM. Esta actividad se generó en la corteza inferior dominada por la concentración de gabros, dioritas y rocas híbridas (granulitas máficas. Debido a un engrosamiento de la corteza como consecuencia de la actividad tectónica durante Mioceno superior o por el estancamiento de magmas o por la combinación de ambos procesos, la formación de granulitas granatíferas resultó un producto distintivo de la corteza inferior. Con el desarrollo del arco magmático (CEH en el Mioceno superior, los magmas ascendieron desde la fuente mantélica, encontrándose con una corteza inferior granatífera, perdiendo capacidad de ascenso por falta de contraste de densidades, produciéndose una fusión extendida, la homogeinización y el ascenso, en equilibrio con la corteza baja, proceso que caracteriza el volcanismo de un arco magmático.The petrology and geochemistry of the exposed Tertiary volcanic units in southern Mendoza Province are described for the first time. The formal stratigraphic nomenclature and ages are analyzed and a stratigraphic basis is established for successive magmatic events occurring during the Neogene, starting with the evolution of

  8. Labelling GM-free Products

    DEFF Research Database (Denmark)

    Punt, Maarten; Venus, Thomas; Wesseler, Justus

    2016-01-01

    Food suppliers in the EU must comply with labelling regulations for genetically modified organisms (GMOs). However, excluded from mandatory labelling are food products derived from animals fed with GM feed (mainly GM soybean in the EU). Because of this labelling exemption, consumers are unable to...

  9. The unusual photometric variability of the PMS star GM Cep

    CERN Document Server

    Semkov, E; Peneva, S; Milanov, T; Stoyanov, K; Stateva, I; Kjurkchieva, D; Dimitrov, D; Radeva, V

    2015-01-01

    Results from UBVRI photometric observations of the pre-main sequence star GM Cep obtained in the period April 2011 - August 2014 are reported in the paper. Presented data are a continuation of our photometric monitoring of the star started in 2008. GM Cep is located in the field of the young open cluster Trumpler 37 and over the past years it has been an object of intense photometric and spectral studies. The star shows a strong photometric variability interpreted as a possible outburst from EXor type in previous studies. Our photometric data for a period of over six years show a large amplitude variability (Delta V ~ 2.3 mag.) and several deep minimums in brightness are observed. The analysis of the collected multicolor photometric data shows the typical of UX Ori variables a color reversal during the minimums in brightness. The observed decreases in brightness have a different shape, and evidences of periodicity are not detected. At the same time, high amplitude rapid variations in brightness typical for th...

  10. Moving beyond the GM debate.

    Directory of Open Access Journals (Sweden)

    Ottoline Leyser

    2014-06-01

    Full Text Available Once again, there are calls to reopen the debate on genetically modified (GM crops. I find these calls frustrating and unnecessarily decisive. In my opinion the GM debate, on both sides, continues to hamper the urgent need to address the diverse and pressing challenges of global food security and environmental sustainability. The destructive power of the debate comes from its conflation of unrelated issues, coupled with deeply rooted misconceptions of the nature of agriculture.

  11. Moving beyond the GM debate.

    Science.gov (United States)

    Leyser, Ottoline

    2014-06-01

    Once again, there are calls to reopen the debate on genetically modified (GM) crops. I find these calls frustrating and unnecessarily decisive. In my opinion the GM debate, on both sides, continues to hamper the urgent need to address the diverse and pressing challenges of global food security and environmental sustainability. The destructive power of the debate comes from its conflation of unrelated issues, coupled with deeply rooted misconceptions of the nature of agriculture.

  12. The Wine Clusters of Mendoza and Serra Gaúcha: A Local Development Perspective

    Directory of Open Access Journals (Sweden)

    María Verónica ALDERETE

    2014-01-01

    Full Text Available This paper consists of a descriptive analysis that explains how the successful performance of the wine cluster is followed by improvements in local development indicators. To this end, certain local development indicators are proposed to describe and compare the wine clusters of Mendoza (Argentina and Serra Gaúcha (Brazil. In Argentina, the Mendoza wine cluster has stimulated the local development of the region. For its part, Serra Gaúcha is the most successful wine center in Brazil and regards Mendoza as the benchmark in terms of local development.

  13. How do GM / non GM coexistence regulations affect markets and welfare?

    OpenAIRE

    Desquilbet, Marion; Sylvaine PORET

    2012-01-01

    This paper presents a theoretical economic model assessing the effects of the level of mandatory genetically modified (GM) / non-GM coexistence regulations on market and welfare outcomes. We assume vertical differentiation of GM and non-GM goods on the consumer side. Producers are heterogeneous in their production cost for GM crops. Producers of non- GM crops face a probability of having their harvest downgraded if gene flow from GM fields raises its content in GMOs (geneticall...

  14. How do GM / non GM coexistence regulations affect markets and welfare?

    OpenAIRE

    Desquilbet, Marion; Sylvaine PORET

    2012-01-01

    This paper presents a theoretical economic model assessing the effects of the level of mandatory genetically modified (GM) / non-GM coexistence regulations on market and welfare outcomes. We assume vertical differentiation of GM and non-GM goods on the consumer side. Producers are heterogeneous in their production cost for GM crops. Producers of non- GM crops face a probability of having their harvest downgraded if gene flow from GM fields raises its content in GMOs (genetically modified orga...

  15. The future of starch bioengineering: GM microorganisms or GM plants?

    DEFF Research Database (Denmark)

    Hebelstrup, Kim; Sagnelli, Domenico; Blennow, Andreas

    2015-01-01

    Plant starches regularly require extensive modification to permit subsequent applications. Such processing is usually done by the use of chemical and/or physical treatments. The use of recombinant enzymes produced by large-scale fermentation of GM microorganisms is increasingly used in starch...... processing and modification, sometimes as an alternative to chemical or physical treatments. However, as a means to impart the modifications as early as possible in the starch production chain, similar recombinant enzymes may also be expressed in planta in the developing starch storage organ such as in roots......, tubers and cereal grains to provide a GM crop as an alternative to the use of enzymes from GM microorganisms. We here discuss these techniques in relation to important structural features and modifications of starches such as: starch phosphorylation, starch hydrolysis, chain transfer/branching and novel...

  16. 76 FR 80870 - Notice of Determination of Pest-Free Areas in Mendoza Province, Argentina

    Science.gov (United States)

    2011-12-27

    ... additional areas as pest-free areas for Mediterranean fruit fly (Ceratitis capitata) in Argentina. We... that, in addition to the pest-free status for C. capitata, the Mendoza province of Argentina also...

  17. El palacio de don Antonio de Mendoza en Guadalajara. Aspectos decorativos y formales

    Directory of Open Access Journals (Sweden)

    Rodríguez Rebollo, Ángel

    2002-09-01

    Full Text Available The Palace of Don Antonio de Mendoza in Guadalajara was constructed at the beginning of the sixteenth century. In spite of the absence of documentation, there are clear stylistic similarities between this palace and the Calahorra Palace (Granada and the tomb of Cardinal Mendoza. The Codex Escurialensis was used for the decoration of the first floor column capitals as well as the façade decoration.

    El Palacio de Don Antonio de Mendoza en Guadalajara fue construido a principios del XVI. Pese a no estar documentado, las similitudes estilísticas con el Palacio de la Calahorra (Granada y el sepulcro del Cardenal Mendoza son claros. El Codex Excurialensis fue usado en la decoración de los capiteles del primer piso y en la decoración de la fachada principal.

  18. The future of starch bioengineering: GM microorganisms or GM plants?

    Directory of Open Access Journals (Sweden)

    Kim Henrik eHebelstrup

    2015-04-01

    Full Text Available Plant starches regularly require extensive modification to permit subsequent applications. Such processing is usually done by the use of chemical and/or physical treatments. The use of recombinant enzymes produced by large-scale fermentation of GM microorganisms is increasingly used in starch processing and modification, sometimes as an alternative to chemical or physical treatments. However, as a means to impart the modifications as early as possible in the starch production chain, similar recombinant enzymes may also be expressed in planta in the developing starch storage organ such as in roots, tubers and cereal grains to provide a GM crop as an alternative to the use of enzymes from GM microorganisms. We here discuss these techniques in relation to important structural features and modifications of starches such as: starch phosphorylation, starch hydrolysis, chain transfer/branching and novel concepts of hybrid starch-based polysaccharides. In planta starch bioengineering is generally challenged by yield penalties and inefficient production of the desired product. However in some situations, GM crops for starch bioengineering without deleterious effects have been achieved.

  19. Acceptability of GM foods among Pakistani consumers.

    Science.gov (United States)

    Ali, Akhter; Rahut, Dil Bahadur; Imtiaz, Muhammad

    2016-04-02

    In Pakistan majority of the consumers do not have information about genetically modified (GM) foods. In developing countries particularly in Pakistan few studies have focused on consumers' acceptability about GM foods. Using comprehensive primary dataset collected from 320 consumers in 2013 from Pakistan, this study analyzes the determinants of consumers' acceptability of GM foods. The data was analyzed by employing the bivariate probit model and censored least absolute deviation (CLAD) models. The empirical results indicated that urban consumers are more aware of GM foods compared to rural consumers. The acceptance of GM foods was more among females' consumers as compared to male consumers. In addition, the older consumers were more willing to accept GM food compared to young consumers. The acceptability of GM foods was also higher among wealthier households. Low price is the key factor leading to the acceptability of GM foods. The acceptability of the GM foods also reduces the risks among Pakistani consumers.

  20. How do GM / non GM coexistence regulations affect markets and welfare?

    OpenAIRE

    Desquilbet, Marion; Sylvaine PORET

    2011-01-01

    This paper presents a theoretical economic model assessing the effect of the level of mandatory genetically modified (GM) / non-GM coexistence regulations on market and welfare outcome. We assume vertical differentiation of GM and non-GM goods on the consumer side. Producers are heterogeneous in their cost savings from GMO adoption. Producers of non-GM crops face a probability of having their harvest downgraded if gene flow from GM fields makes its GMO content above the labeling threshold. Th...

  1. Urban mobility regulation in metropolitan area of Mendoza

    Directory of Open Access Journals (Sweden)

    Lía Martínez

    2016-11-01

    Full Text Available Achieving the paradigm of sustainable urban mobility requires institutional capacities, appropriate policies and a regulatory framework that contains them. This work aims to contribute to the knowledge of the regulation of urban mobility in the metropolitan area of Mendoza. To this end, the current mobility regulations are assessed through indicators that are classified into three key areas: institutional and political organization, urban system and financial setup. The purpose is to account for the existence, or not, of regulatory capacities contained in the paradigm of sustainable mobility. Among the results, the absence of a policy of sustainable urban mobility is noteworthy, as well as the lack of sectorial coordination. Also of note is the absence of coordination between the urban planning system and the public transport provision. Lastly, in the financial sector, the results point to a promotion of sustainable transport modes but without such an explicit purpose.

  2. Optical photometry of GM Cep: evidence for UXor type of variability

    Science.gov (United States)

    Semkov, E. H.; Peneva, S. P.

    2012-03-01

    Results from optical photometric observations of the pre-main sequence star GM Cep are reported in the paper. The star is located in the field of the young open cluster Trumpler 37—a region of active star formation. GM Cep shows a large amplitude rapid variability interpreted as a possible outburst from EXor type in previous studies. Our data from BVRI CCD photometric observations of the star are collected from June 2008 to February 2011 in Rozhen observatory (Bulgaria) and Skinakas observatory (Crete, Greece). A sequence of sixteen comparison stars in the field of GM Cep was calibrated in the BVRI bands. Our photometric data for a 2.5 years period show a high amplitude variations (Δ V ˜2. m3) and two deep minimums in brightness are observed. The analysis of collected multicolor photometric data shows the typical of UX Ori variables a color reversal during the minimums in brightness. On the other hand, high amplitude rapid variations in brightness typical for the Classical T Tauri stars also present on the light curve of GM Cep. Comparing our results with results published in the literature, we conclude that changes in brightness are caused by superposition of both: (1) magnetically channeled accretion from the circumstellar disk, and (2) occultation from circumstellar clouds of dust or from features of a circumstellar disk.

  3. GM3, GM2 and GM1 mimics designed for biosensing: chemoenzymatic synthesis, target affinities and 900 MHz NMR analysis

    NARCIS (Netherlands)

    Pukin, A.V.; Weijers, C.A.G.M.; van Lagen, B.; Wechselberger, R.W.; Sun, B.; Gilbert, M.; Karwaski, M.F.; Florack, D.E.A.; Jacobs, B.C.; Tio-Gillen, A.P.; van Belkum, A.; Endtz, H.P.; Visser, G.M.; Zuilhof, H.

    2008-01-01

    Undec-10-enyl, undec-10-ynyl and 11-azidoundecyl glycoside analogues corresponding to the oligosaccharides of human gangliosides GM3, GM2 and GM1 were synthesized in high yields using glycosyltransferases from Campylobacter jejuni. Due to poor water solubility of the substrates, the reactions were c

  4. Americans Divided Over Organic, GM Foods: Poll

    Science.gov (United States)

    ... gov/news/fullstory_162314.html Americans Divided Over Organic, GM Foods: Poll Their opinions aren't driven by politics ... News) -- Americans are split on the value of organic foods and concerns about genetically modified (GM) foods, a ...

  5. Genetics Home Reference: GM3 synthase deficiency

    Science.gov (United States)

    ... Facebook Share on Twitter Your Guide to Understanding Genetic Conditions Search MENU Toggle navigation Home Page Search ... Conditions Genes Chromosomes & mtDNA Resources Help Me Understand Genetics Home Health Conditions GM3 synthase deficiency GM3 synthase ...

  6. Detection of a Proto-planetary Clump in the Habitable Zone of GM Cephei

    Science.gov (United States)

    Chen, W. P.; Hu, S. C.-L.

    2014-04-01

    GM Cephei is an active T Tauri star in the young open cluster Trumpler 37, showing abrupt UX Orionis type of photometric variability. Its light curves exhibit frequent, sporadic brightening events, each of <0.5 mag and lasting for days, which must have been originated from unsteady circumstellar accretion. In addition, the star undergoes a brightness drop up to ~1 mag lasting for about a month, during which the star became bluer when fainter. Moreover, the brightness drops seem to have a recurrence timescale of about 300 days. It is proposed that the brightness drop arises from obscuration of the central star by an orbiting dust concentration, exemplifying disk inhomogeneity in transition between grain coagulation and planetesimal formation in a young circumstellar disk. GM Cep was found to show a few percent polarization in the optical wavelengths, and an enhanced level of polarization during the occultation phase.

  7. Discussion of "The Internal Correlation: Its Applications in Statistics and Psychometrics" by G. W. Joe and J. L. Mendoza.

    Science.gov (United States)

    Bargmann, Rolf

    1989-01-01

    Use of internal correlation for statistical analysis--as proposed by G. W. Joe and J. L. Mendoza (1989)--is discussed. Use of the bootstrap technique to deal with the distributional problem is questioned. Joe and Mendoza attempt the interpretation of the two linear composites that produce the largest internal correlation. (TJH)

  8. Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity.

    Science.gov (United States)

    Anheuser, Susi; Breiden, Bernadette; Schwarzmann, Günter; Sandhoff, Konrad

    2015-09-01

    Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease. It also accumulates in Niemann-Pick disease types A and B with primary storage of SM and with cholesterol in type C. Reconstitution of GM2 catabolism with β-hexosaminidase A and GM2 activator protein (GM2AP) at uncharged liposomal surfaces carrying GM2 as substrate generated only a physiologically irrelevant catabolic rate, even at pH 4.2. However, incorporation of anionic phospholipids into the GM2 carrying liposomes stimulated GM2 hydrolysis more than 10-fold, while the incorporation of plasma membrane stabilizing lipids (SM and cholesterol) generated a strong inhibition of GM2 hydrolysis, even in the presence of anionic phospholipids. Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies. These lipids also reduced the interliposomal transfer rate of 2-NBD-GM1 by GM2AP, as observed in assays using Förster resonance energy transfer. Our data raise major concerns about the usage of recombinant His-tagged GM2AP compared with untagged protein. The former binds more strongly to anionic GM2-carrying liposomal surfaces, increases GM2 hydrolysis, and accelerates intermembrane transfer of 2-NBD-GM1, but does not mobilize membrane lipids.

  9. Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity[S

    Science.gov (United States)

    Anheuser, Susi; Breiden, Bernadette; Schwarzmann, Günter; Sandhoff, Konrad

    2015-01-01

    Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease. It also accumulates in Niemann-Pick disease types A and B with primary storage of SM and with cholesterol in type C. Reconstitution of GM2 catabolism with β-hexosaminidase A and GM2 activator protein (GM2AP) at uncharged liposomal surfaces carrying GM2 as substrate generated only a physiologically irrelevant catabolic rate, even at pH 4.2. However, incorporation of anionic phospholipids into the GM2 carrying liposomes stimulated GM2 hydrolysis more than 10-fold, while the incorporation of plasma membrane stabilizing lipids (SM and cholesterol) generated a strong inhibition of GM2 hydrolysis, even in the presence of anionic phospholipids. Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies. These lipids also reduced the interliposomal transfer rate of 2-NBD-GM1 by GM2AP, as observed in assays using Förster resonance energy transfer. Our data raise major concerns about the usage of recombinant His-tagged GM2AP compared with untagged protein. The former binds more strongly to anionic GM2-carrying liposomal surfaces, increases GM2 hydrolysis, and accelerates intermembrane transfer of 2-NBD-GM1, but does not mobilize membrane lipids. PMID:26175473

  10. Burkina Faso - BRIGHT II

    Data.gov (United States)

    Millennium Challenge Corporation — Millennium Challenge Corporation hired Mathematica Policy Research to conduct an independent evaluation of the BRIGHT II program. The three main research questions...

  11. Rural workers in the Uco Valley (Mendoza, Argentina Asalariados rurales en el Valle de Uco (Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Elena Mingo

    2009-01-01

    Full Text Available This paper analyze labor insertion of agricultural workers in the Uco Valley, Mendoza. We assume that agricultural labor market characteristics determine labor insertions generating occupational social practices which arises in dispositions, layouts and strategies of these workers. These workers are characterized by his insertion in precarious and/or unstable jobs, by getting low and discontinuous incomes and by the frequent social vulnerability of the households they belongs to. This article describes labor relations as a social field in which Uco Valley's agricultural workers participate. Then, we analyze some elements associated to socialization at work, a relevant aspect to understand social relationships that underlies the constitution of agricultural labor market and dispositions of agricultural workers. Next, we describe and analyze some elements that condition labor insertion forming agricultural worker's labor strategies. Finally, we examined household influence in labor insertion of their members.El objetivo de este artículo es analizar la inserción laboral de los trabajadores agrícolas asalariados en el Valle de Uco, provincia de Mendoza. Partimos de entender que las características del mercado de trabajo agrícola condicionan las inserciones laborales generando prácticas sociales ocupacionales que se expresan en disposiciones, orientaciones y estrategias de estos trabajadores. Estos trabajadores se caracterizan por una inserción laboral precaria y/o inestable y la percepción de ingresos insuficientes y discontinuos, a lo que se suman las frecuentes condiciones de vulnerabilidad social de sus hogares de pertenencia. El artículo contiene una descripción de la esfera laboral en tanto campo social en que se desempeñan los trabajadores agrícolas en el Valle de Uco. Luego analizamos algunos elementos vinculados a la socialización en el trabajo, aspecto importante para comprender las relaciones sociales que fundamentan la

  12. Quaternary Glaciations in the Rio Mendoza Valley, Argentine Andes

    Science.gov (United States)

    Espizua, Lydia E.

    1993-09-01

    In the Rio Mendoza valley, five Pleistocene drifts and one Holocene drift are distinguished by multiple relative-age criteria, including surface-rock weathering, development of rock varnish, moraine morphology, soil-profile development, and stratigraphic relationships. Several absolute ages suggest a preliminary chronology. During the oldest (Uspallata) glaciation, a system of valley glaciers flowed 110 km from the Andean drainage divide and 80 km from Cerro Aconcagua to terminate at 1850 m. Drift of this ice advance is older than a widespread tephra dated by fission-track at 360,000 ± 36,000 yr. During the Punta de Vacas advance, ice terminated at 2350 m, while during the subsequent Penitentes advance, the glacier system ended at 2500 m. A travertine layer overlying Penitentes Drift has U-series age of 24,200 ± 2000 yr B.P. The distribution of Horcones Drift, which is inferred to represent the last glacial maximum, delimits an independent ice stream that flowed 22 km down Horcones valley to 2750 m. A later readvance (Almacenes) reached 3250 m. Confluencia Drift is considered to be Neoglacial in age and extends downvalley to 3300 m. The moraine sequence is compared with those studied by Caviedes (1972) along Rio Aconcagua on the Chilean flank of the Andes.

  13. Genetically Modified (GM) Foods and Ethical Eating.

    Science.gov (United States)

    Dizon, Francis; Costa, Sarah; Rock, Cheryl; Harris, Amanda; Husk, Cierra; Mei, Jenny

    2016-02-01

    The ability to manipulate and customize the genetic code of living organisms has brought forth the production of genetically modified organisms (GMOs) and consumption of genetically modified (GM) foods. The potential for GM foods to improve the efficiency of food production, increase customer satisfaction, and provide potential health benefits has contributed to the rapid incorporation of GM foods into the American diet. However, GM foods and GMOs are also a topic of ethical debate. The use of GM foods and GM technology is surrounded by ethical concerns and situational judgment, and should ideally adhere to the ethical standards placed upon food and nutrition professionals, such as: beneficence, nonmaleficence, justice and autonomy. The future of GM foods involves many aspects and trends, including enhanced nutritional value in foods, strict labeling laws, and potential beneficial economic conditions in developing nations. This paper briefly reviews the origin and background of GM foods, while delving thoroughly into 3 areas: (1) GMO labeling, (2) ethical concerns, and (3) health and industry applications. This paper also examines the relationship between the various applications of GM foods and their corresponding ethical issues. Ethical concerns were evaluated in the context of the code of ethics developed by the Academy of Nutrition and Dietetics (AND) that govern the work of food and nutrition professionals. Overall, there is a need to stay vigilant about the many ethical implications of producing and consuming GM foods and GMOs.

  14. The world of "GM-free".

    Science.gov (United States)

    Moses, Vivian; Brookes, Graham

    2013-01-01

    The rapid global development of agricultural production systems using seeds derived from genetic modification (GM) has been paralleled by the growth of attempts to keep at least a part of the world's agriculture and food as free from GM-crops and their products as possible. The ideal for some proponents of such "GM-free" activity would be a total absence, usually styled "zero content"; others, perhaps more realistically, opt for a definition usually not precisely defined that allows for minimal trace levels of GM material. The reasons for wanting "GM-free" agriculture and its products are varied; they include philosophical and religious beliefs, concern for human (and animal) health--and for "the environment"-as well as commercial and political interests. With such a variety of motivations, and in the absence of legal rulings, the definitions of "GM-free" vary according to inclination and circumstances. Whatever the precise meaning, the maintenance of a "GM-free" product stream in a world where GM crop production is widespread requires the establishment of identity preservation and segregation systems in which traceability and testing are cornerstones. Inevitably these have cost implications for the supply chain and/or the ultimate consumer. In a number of countries different forms of "GM-free" labels exist for some products; the style of such labels is variable with schemes and labels typically voluntary or privately organized. In more recent years, some governments have begun to regularize the definition and meaning of "GM-free." We conclude our analysis by exploring consumer reactions both to "GM-free" and to "GM-free" labels, and ask who ultimately benefits from preserving a product stream substantially or entirely devoid of GM-content.

  15. Eduardo Mendoza y la parodia del género de la novela policiaca

    OpenAIRE

    Brezmes Calderón, Nicolás

    2015-01-01

    El tema que se va a tratar en estas páginas es el tratamiento humorístico que hace Eduardo Mendoza respecto a los elementos del género de la novela policíaca, en sus obras El misterio de la cripta embrujada (1979), El laberinto de las aceitunas (1982) y La aventura del tocador de señoras (2001). Se han elegido estas tres obras para el trabajo porque conforman una trilogía donde queda patente la maestría de Mendoza para narrar una historia a través del humor, y porque la primera de ellas supus...

  16. Chaco ansilta new species from Mendoza province, Western Argentina (Araneae: Nemesiidae

    Directory of Open Access Journals (Sweden)

    NELSON FERRETTI

    2014-12-01

    Full Text Available A new species of Chaco Tullgren, 1905 is described and illustrated from the Andean foothills of Mendoza province, western Argentina. This is the tenth species of the genus and the first record of Chaco in Mendoza. An updated key is presented for all Chaco species. The cladistic analysis based on a previously published morphological character matrix resulted in the consensus tree: (C. obscura, C. tucumana, C. castanea, (C. socos + C. tigre (C. tecka (C. sanjuanina (C. Patagonia + C. ansilta sp. nov..

  17. Economic impact of GM crops

    Science.gov (United States)

    Brookes, Graham; Barfoot, Peter

    2014-01-01

    A key part of any assessment of the global value of crop biotechnology in agriculture is an examination of its economic impact at the farm level. This paper follows earlier annual studies which examined economic impacts on yields, key costs of production, direct farm income and effects, and impacts on the production base of the four main crops of soybeans, corn, cotton and canola. The commercialization of genetically modified (GM) crops has continued to occur at a rapid rate, with important changes in both the overall level of adoption and impact occurring in 2012. This annual updated analysis shows that there have been very significant net economic benefits at the farm level amounting to $18.8 billion in 2012 and $116.6 billion for the 17-year period (in nominal terms). These economic gains have been divided roughly 50% each to farmers in developed and developing countries. GM technology have also made important contributions to increasing global production levels of the four main crops, having added 122 million tonnes and 230 million tonnes respectively, to the global production of soybeans and maize since the introduction of the technology in the mid-1990s. PMID:24637520

  18. Photometry and Polarization of the UXor Type Young Star GM Cep

    Science.gov (United States)

    Huang, Po-Chieh; Chen, Chang-Yao; Hu, Chia-Ling; Chen, Wen-Ping

    2015-08-01

    UX Orionis stars, or UXORs, are a sub-type of Herbig Ae/be or T Tauri stars exhibiting sporadic extinction of stellar light due to circumstellar dust obscuration. GM Cep is such a UXOR in the young (~4 Myr) open cluster Trumper 37 at ~900 pc, showing prominent infrared access, H-alpha emission, and abrupt brightness variation. Here we present intense multi-color photometric monitoring from 2009 to 2015, together with the century-long photometric behavior reported in the literature, to add to the study by Chen et al. (2012) that GM Cep showed (i) sporadic brightening on a time scale of days due to young stellar accretion, (ii) occultation events, each lasting for a couple months, with a probable recurrence time of about two years, (iii) normal dust reddening as the star became redder when dimmer, (iv) the unusual “blueing” phenomena near the brightness minima when the star appeared bluer when dimmer. The occultation events may be caused by a dust clump, signifying the density inhomogeneity in a young stellar disk from grain coagulation to planetesimal formation. We present evidence of possible radial drift of the clump toward the star, stretching longer along the orbit and thinner in the line of sight. GM Cep is moderately polarized, from 4% to 9% in g, r, and i bands, with the level of polarization anticorrelated with the brightness in the bright state, during which the dust clump is back-scattering stellar light.

  19. Sunspot Bright Points

    CERN Document Server

    Choudhary, Debi Prasad

    2010-01-01

    We used the flux calibrated images through the Broad Band Filter Imager and Stokes Polarimeter data obtained with the Solar Optical Telescope onboard the Hinode spacecraft to study the properties of bright points in and around the sunspots. The well isolated bright points were selected and classified as umbral dot, peripheral umbral dot, penumbral grains and G-band bright point depending on their location. Most of the bright points are smaller than about 150 km. The larger points are mostly associated with the penumbral features. The bright points are not uniformly distributed over the umbra but preferentially located around the penumbral boundary and in the fast decaying parts of umbra. The color temperature of the bright points, derived using the continuum irradiance, are in the range of 4600 K to 6600 K with cooler ones located in the umbra. The temperature increases as a function of distance from the center to outside. The G-band, CN-band and CaII H flux of the bright points as a function of their blue ba...

  20. Primer registro de Tityus trivittatus (Scorpiones: Buthidae en la provincia de Mendoza (Argentina First record of Tityus trivittatus (Scorpiones: Buthidae in Mendoza province (Argentina

    Directory of Open Access Journals (Sweden)

    Florencia Fernández Campón

    2009-06-01

    Full Text Available En la siguiente nota se informa sobre el primer registro del escorpión Tityus trivittatus Kraepelin en la provincia de Mendoza en el Barrio Campo Papa, departamento de Godoy Cruz. T trivittatus es dentro de nuestro país una de las especies de escorpiones con importancia médica, debido a que su veneno neurotóxico puede causar lesiones en el sistema nervioso y en algunos casos la muerte, particularmente en niños.This note reports the first record on the scorpion Tityus trivittatus Kraepelin in Mendoza province in the locality of Campo Papa, Godoy Cruz. T. trivittatus is one of the species of scorpion of medical importance in Argentina, due to the fact that its neurotoxic venom can damage the nervous system and may even be fatal in some cases, especially among children.

  1. ESTUDIO ARQUEOHISTÓRICO DEL REGISTRO VÍTREO EN SITIOS MINEROS (MENDOZA, ARGENTINA (Archaeohistorical Study of the Vitreous Record in Mining Sites (Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Osvaldo Sironi

    2017-06-01

    Full Text Available Se presentan los resultados de los análisis de los registros vítreos de los sitios Minas Paramillos Sur y Mina La Atala, localizados en la Reserva Natural Villavicencio y Divisadero Largo. A partir del conocimiento de la materialidad cultural vítrea de esta región, se evidencian patrones de consumo vinculados a diversos tipos de bebidas y productos medicinales entre la clase trabajadora minera de la Precordillera de Mendoza (Argentina. ENGLISH: Results of the analysis of the vitreous record from Minas Paramillos Sur and Mina La Atala are presented. These sites are located in the Villavicencio and Divisadero Largo natural reserves. Knowledge of the vitreous cultural material of this region allows us to show consumption patterns of various types of beverages and medicines among the mining working class of the Mendoza Precordillera, Argentina.

  2. GmACP expression is decreased in GmNORK knockdown transgenic soybean roots

    Institute of Scientific and Technical Information of China (English)

    Lijun Wang; Lingwei Deng

    2016-01-01

    NORK and soybean acyl carrier protein (ACP) both play important roles in nodulation. However, the relationship between Nod factor signaling and fatty acid (FA) biosynthesis during symbiotic development is unknown. In this study, an RNAi plasmid of GmNORK was constructed and transformed into soybean roots by Agrobacterium rhizogene-mediated hairy-root transformation. The nodule number decreased substantially in GmNORK knock-down soybean transgenic roots. To investigate the relationship between GmACP and Nod factor signaling, we measured GmACP expression levels in GmNORK RNAi soybean transgenic roots and found that rhizobia inoculation led to substantially reduced GmACP expression. Thus, FA biosynthesis was affected by Nod factor signaling during nodule development in soybean, a finding that provides valuable information that improves our understanding of the functions of GmNORK and GmACP in symbiotic signaling and nodule development.

  3. 76 FR 51934 - Determination of Pest-Free Areas in Mendoza Province, Argentina; Request for Comments

    Science.gov (United States)

    2011-08-19

    ... of that country as being free of Ceratitis capitata, Mediterranean fruit fly (Medfly). Specifically... recognize additional areas as pest-free areas for Mediterranean fruit fly (Ceratitis capitata) in Argentina... Ceratitis capitata, the Mendoza province of Argentina also be recognized as free of A. fraterculus. \\2\\...

  4. Programa de Desarrollo Productivo y Competitividad de la Provincia de Mendoza (AR-L1003)

    OpenAIRE

    Gobierno de Mendoza

    2005-01-01

    Presentación que da a conocer el programa de desarrollo productivo del Gobierno de Mendoza: diagnóstico, finalidad, objetivo, fases del programa, infraestructura pública, acceso al financiamiento, capacitación laboral y promoción de clusters.

  5. [Bright light therapy].

    Science.gov (United States)

    Poirrier, R; Cambron, L

    2007-01-01

    Bright light therapy is a treatment that emerged in the eighties of the last century. It can be used in different pathologies such as seasonal affective disorders, major depressions, and many disorders of the wake-sleep rhythm, whether they are of primary or secondary origin. Important progress made at the basic neuroscience levels, allows today a sound understanding of the bright light mode of action. Moreover, the main indications are now the subject of consensus reports and meta-analyses which show good levels of evidence-based medicine. Bright light therapy constitutes a first choice indication in seasonal affective disorder. It is also perfectly possible to prescribe bright light therapy in the major depression disorders. It has been demonstrated that the effect size is the same as with antidepressants of reference. It is admitted nowadays that bright light therapy may be at least, an adjunct to pharmacotherapy, in order to accelerate the antidepressant effect onset, or to prolong this effect after withdrawal of the drug. Bright light therapy can also be viewed as an alternative to the pharmacological approach especially when this one is impossible, not tolerated or not accepted by the patient. The contraindications are rare.

  6. A POSSIBLE DETECTION OF OCCULTATION BY A PROTO-PLANETARY CLUMP IN GM Cephei

    Energy Technology Data Exchange (ETDEWEB)

    Chen, W. P.; Hu, S. C.-L.; Guo, J. K.; Hsiao, H. Y.; Lin, H. C.; Lin, C. S. [Graduate Institute of Astronomy, National Central University, 300 Jhongda Road, Jhongli 32001, Taiwan (China); Errmann, R.; Adam, Ch.; Baar, S.; Berndt, A.; Eisenbeiss, T.; Fiedler, S.; Ginski, Ch.; Graefe, C.; Hohle, M. M.; Kitze, M.; Maciejewski, G. [Astrophysikalisches Institut und Universitaets-Sternwarte, FSU Jena, Schillergaesschen 2-3, D-07745 Jena (Germany); Bukowiecki, L. [Torun Centre for Astronomy, Nicolaus Copernicus University, Gagarina 11, PL87-100 Torun (Poland); Dimitrov, D. P. [Institute of Astronomy and NAO, Bulg. Acad. Sc., 72 Tsarigradsko Chaussee Blvd., 1784 Sofia (Bulgaria); Janulis, R. [Moletai Observatory, Vilnius University (Lithuania); and others

    2012-06-01

    GM Cephei (GM Cep), in the young ({approx}4 Myr) open cluster Trumpler 37, has been known to be an abrupt variable and to have a circumstellar disk with a very active accretion. Our monitoring observations in 2009-2011 revealed that the star showed sporadic flare events, each with a brightening of {approx}< 0.5 mag lasting for days. These brightening events, associated with a color change toward blue, should originate from increased accretion activity. Moreover, the star also underwent a brightness drop of {approx}1 mag lasting for about a month, during which time the star became bluer when fainter. Such brightness drops seem to have a recurrence timescale of a year, as evidenced in our data and the photometric behavior of GM Cep over a century. Between consecutive drops, the star brightened gradually by about 1 mag and became blue at peak luminosity. We propose that the drop is caused by the obscuration of the central star by an orbiting dust concentration. The UX Orionis type of activity in GM Cep therefore exemplifies the disk inhomogeneity process in transition between the grain coagulation and the planetesimal formation in a young circumstellar disk.

  7. A Reply to Thomas W. Mendoza-Harrell, "The Foreign Language Laboratory and the Future of Language Teaching"

    Science.gov (United States)

    Allen, John R.

    1976-01-01

    Portions of Mendoza-Harrell's article, which is a rebuttal of an earlier article by Allen, are mentioned and criticized. Allen's earlier article discussed the efficacy of language laboratories and proposed student use of cassette recorders. (RM)

  8. Optical photometry of GM Cep: evidence for UXor type of variability

    CERN Document Server

    Semkov, E H

    2011-01-01

    Results from optical photometric observations of the pre-main sequence star GM Cep are reported in the paper. The star is located in the field of the young open cluster Trumpler 37 - a region of active star formation. GM Cep shows a large amplitude rapid variability interpreted as a possible outburst from EXor type in previous studies. Our data from BVRI CCD photometric observations of the star are collected from June 2008 to February 2011 in Rozhen observatory (Bulgaria) and Skinakas observatory (Crete, Greece). A sequence of sixteen comparison stars in the field of GM Cep was calibrated in the BVRI bands. Our photometric data for a 2.5 years period show a high amplitude variations (Delta V ~ 2.3m) and two deep minimums in brightness are observed. The analysis of collected multicolor photometric data shows the typical of UX Ori variables a color reversal during the minimums in brightness. On the other hand, high amplitude rapid variations in brightness typical for the Classical T Tauri stars also present on ...

  9. GM1 gangliosidosis: Case report

    Directory of Open Access Journals (Sweden)

    Obradović Slobodan

    2010-01-01

    Full Text Available Introduction. Gangliosidoses occur due to inhereted deficiency of human β - galaktosidase,resulting in the accumulation of glicophyngolipides within the lisosomes. Clinical manifestations of lysosomal storage disorders are remarkably heterogeneous, they can appear at any age and each of them can vary from mild to severe conditions. Case report. We present a patient with an early, infintile type of GM1 gangliosidosis. The facial features were coarse: hypertelorismus, wide nose, depressed nasal bridge with lingual protrusion. From the very first months of life she had severe generalized hypotonic, delayed development and hapatosplenomegaly. Before she died, when she was 13 months old, she had not had any spontaneus movements, she was deaf and blind, dispnoic, with apnoiccrises, with amimic face, but without seizures and decerebrate rigidity, which often accompanies the terminal stage of this illness. Conclusion. The absence of β-galaktosidase enzyme activaty at the skin fibroblasts confirmed the definitive diagnosis. There has been no successful treatment so far, but increasingly better results of the gene therapy for other lysosomal storage disorders can make us optimistic.

  10. Quaternary continetal back-arc evolution from southern Mendoza, Argentina

    Science.gov (United States)

    Espanon, Venera; Chivas, Allan; Dosseto, Anthony; Honda, Masahiko; Phillips, David; Matchan, Erin; Price, David

    2016-04-01

    The Quaternary evolution of the Payenia Basaltic Province (PBP) in southern Mendoza, Argentina has been investigated using a multi-dating approach in combination with pre-exiting geochemical data. This basaltic province covers an area of approximately 40000 km2 and is mainly characterised by backarc volcanism. In the current investigation nine new radiometric ages obtained using surface exposure, 40Ar/39Ar and thermoluminescence dating are presented. Six ages correspond to the late Pleistocene and three to the Holocene. The surface exposure ages obtained using cosmogenic 3He and 21Ne are in good agreement with previous publications and confidently suggest that part of this basaltic province was active at least 4000 years ago (taking a conservative approach). In addition, we combined the available geochronological and geochemical data to reconstruct the Quaternary evolution of this basaltic province. This approach was used to create maps of geospatial distribution of trace-element ratios to determine geochemical changes during the Pleistocene. Employing this method it is evident that two geochemical distinct types of magma were erupting at the same time interval within the PBP. In the north eastern part (Nevado volcanic field) of the PBP an arc-like signature is evident, while in the southern part (Río Colorado volcanic field) of the same basaltic province an Ocean Island Basalt (OIB) signature is evident. The arc-like signature in the north eastern part of the PBP, decreased during the Pleistocene in a north-west direction indicated by a reduction in Ba/La and La/Ta in the Nevado and Llancanelo volcanic field. The Holocene volcanism is restricted to the western side of the Payún Matrú volcanic field and is dominated by OIB-like signatures such as high Ta/Hf and low Ba/La and La/Ta. This contribution presents new geochronology for the PBP and confirms that two different types of volcanism occurred simultaneously during the Pleistocene, while the Holocene

  11. El volcanismo del Terciario superior del sur de Mendoza

    Directory of Open Access Journals (Sweden)

    F. E. Nullo

    2002-06-01

    Full Text Available Se describe por primera vez la petrografía y geoquímica de unidades volcánicas terciarias del sur de la provincia de Mendoza. Se analizan la nomenclatura estratigráfica y sus edades, estableciéndose una secuencia de eventos magmáticos ocurridos durante el Neógeno, comenzando con la evolución de un retro-arco, seguido por un arco magmático más joven. Se intenta respetar la nomenclatura estratigráfica existente, sin embargo, la definición de unidades se ha realizado sobre la base de las edades radimétricas y sus edades de cristalización, más sobre sus características petrográficas. La actividad magmática se extiende desde el Oligoceno superior al Mioceno superior, correspondiendo a el Ciclo Eruptivo Molle y el Ciclo Eruptivo Huincán, y comenzó con un episodio magmático basáltico inicial (CEM. Esta actividad se generó en la corteza inferior dominada por la concentración de gabros, dioritas y rocas híbridas (granulitas máficas. Debido a un engrosamiento de la corteza como consecuencia de la actividad tectónica durante Mioceno superior o por el estancamiento de magmas o por la combinación de ambos procesos, la formación de granulitas granatíferas resultó un producto distintivo de la corteza inferior. Con el desarrollo del arco magmático (CEH en el Mioceno superior, los magmas ascendieron desde la fuente mantélica, encontrándose con una corteza inferior granatífera, perdiendo capacidad de ascenso por falta de contraste de densidades, produciéndose una fusión extendida, la homogeinización y el ascenso, en equilibrio con la corteza baja, proceso que caracteriza el volcanismo de un arco magmático.

  12. Flood Risk in Motozintla de Mendoza, Chiapas: An Approximation

    Science.gov (United States)

    Rodriguez, F.; Novelo-Casanova, D. A.

    2012-12-01

    The town of Motozintla de Mendoza (15o 22' N and 92o 15' W) is located southern Chiapas, Mexico, and it is highly exposed to flood hazards. This community has suffered the impact of two disaster events due to this natural hazard in less than ten years, the first one in 1998 and the second one in 2005. The objective of this research is to assess the level of flood risk in the community of Motozintla. The methodology consisted of four steps: (1) Identification of the level of flood hazard; (2) Vulnerability assessment considering weighted variables according to their level of incidence on the local risk conditions; (3) Preparation of risk matrices for each area exposed to floods; and 4) Cartographic representation and spatial analysis of the results. We obtained a Geographical Information System (GIS) map for each group of analyzed vulnerabilities (structural, public services, socio-economic, existing plans in case of contingencies, and risk perception) and one map associated to global vulnerability (overposing of all estimated vulnerabilities). These maps demonstrates that the local conditions of structural vulnerability have a high incidence in the generation of risk, differing from the lack of public basic services, which although unfavorable for the population, it is not a deciding factor for preserving life or housing. Another interesting result is that the lack of preparation of the community to face a disaster generates a higher risk level than the other analyzed socioeconomic conditions. The global vulnerability allowed us to determine with greater detail the flood risk levels in the community. Our results indicate that the area in Motozintla with the highest level of flood risk is located in the margins of the Xelajú river, particularly the region that was flooded in 2005, which is precisely the area where the rivers Xelajú, Allende and La Mina meet and the river flow increases. Unfortunately, the northeasters part of this zone had been populated by people

  13. M@gm@ e i miei ritardi

    Directory of Open Access Journals (Sweden)

    Marina Brancato

    2008-12-01

    Full Text Available Sono certa che M@gm@ continuerà ad essere viatico di riflessione nell’ibridazione con altri saperi. Senza alcun antagonismo. Patrimonio espressivo e strategico nel discorso scientifico.

  14. Geología de la región del Cerro Guanaquero, Río Diamante, Mendoza Geology of Cerro Guanaquero region, Diamante River, Mendoza

    OpenAIRE

    Federico Fuentes; Ramos,Victor A.

    2008-01-01

    El estudio realizado presenta nuevos datos sobre un sector poco conocido de la Cordillera Principal de Mendoza, en la alta cuenca del río Diamante en las adyacencias del cerro Guanaquero, y los primeros datos geocronológicos de sus rocas volcánicas. Las unidades geológicas presentes en el área se dividen en cuatro grupos principales: secuencias sedimentarias mesozoicas marinas y continentales intensamente plegadas y falladas; intrusivos y volcanitas intermedias de edad neógena; rocas volcánic...

  15. Soybean cyclophilin GmCYP1 interacts with an isoflavonoid regulator GmMYB176

    Science.gov (United States)

    Mainali, Hemanta Raj; Vadivel, Arun Kumaran Anguraj; Li, Xuyan; Gijzen, Mark; Dhaubhadel, Sangeeta

    2017-01-01

    Cyclophilins (CYPs) belong to the immunophilin superfamily with peptidyl-prolyl cis-trans isomerase (PPIase) activity. They catalyze the interconversion of the cis- and trans-rotamers of the peptidyl-prolyl amide bond of peptides. A yeast-two-hybrid screening using the isoflavonoid regulator GmMYB176 as bait identified GmCYP1 as one of the interacting proteins in soybean embryos. GmCYP1 localizes both in the nucleus and cytoplasm, and interacts in planta with GmMYB176, in the nucleus, and with SGF14l (a soybean 14-3-3 protein) in the nucleus and the cytoplasm. GmCYP1 contains a single cyclophilin-like domain and displays a high sequence identity with other plant CYPs that are known to have stress-specific function. Tissue-specific expression of GmCYP1 revealed higher expression in developing seeds compared to other vegetative tissues, suggesting their seed-specific role. Furthermore, GmCYP1 transcript level was reduced in response to stress. Since isoflavonoids are involved in plant stress resistance against biotic and abiotic factors, the interaction of GmCYP1 with the isoflavonoid regulators GmMYB176 and 14-3-3 protein suggests its role in defense in soybean. PMID:28074922

  16. Los espinelos del complejo alcalino puestoLa Peña, provincia de Mendoza

    Directory of Open Access Journals (Sweden)

    Eduardo O. Zappettini

    2009-06-01

    Full Text Available En este trabajo sedan a conocer datos mineralógicos y condiciones de cristalización de los espinelos,además de ilmenita, presentes en el Complejo Alcalino Puesto La Peña, provinciade Mendoza. El estudio fue realizado con una microsonda electrónica e incluyelos espinelos: magnetita, ulvöespinelo y espinelo s.s. ferífero.

  17. Mendoza various production scenarios: in search of a commercial fruit growing (1900-1930

    Directory of Open Access Journals (Sweden)

    Florencia Rodriguez Vázquez

    2016-04-01

    Full Text Available The formation of a diversified regional economy in Mendoza finds antecedents in the early twentieth century. Indeed, the leading sectors, entrepreneurs and technicians looked for alternatives in order to clarify the effects of cyclical crises affecting the wine industry, agribusiness main activity of the province. Mode in this period is to attend a transitional period, in which a panorama complexity of agricultural production as a result of the combination of several factors that are detected and analyzed in this paper.

  18. Darwin's observation in South America: what did he find at agua de la zorra, Mendoza province?

    OpenAIRE

    Stella Poma; Vanesa D Litvak; Magdalena Koukharsky; E. Beatriz Maisonnave; Sonia Quenardelle

    2009-01-01

    Scarcely 23 km from Uspallata, along the track of the old national highway 7, lies the district of Agua de la Zorra, in Mendoza province in western Argentina. Charles Darwin visited the area during his South American journeys in the 19th century and discovered a geological sequence that contained a paleoflora never described before. The flora includes an important number of species, particularly what is considered a small conifer forest with many silicified trunks still in life position. Darw...

  19. The brightness of colour.

    Directory of Open Access Journals (Sweden)

    David Corney

    Full Text Available BACKGROUND: The perception of brightness depends on spatial context: the same stimulus can appear light or dark depending on what surrounds it. A less well-known but equally important contextual phenomenon is that the colour of a stimulus can also alter its brightness. Specifically, stimuli that are more saturated (i.e. purer in colour appear brighter than stimuli that are less saturated at the same luminance. Similarly, stimuli that are red or blue appear brighter than equiluminant yellow and green stimuli. This non-linear relationship between stimulus intensity and brightness, called the Helmholtz-Kohlrausch (HK effect, was first described in the nineteenth century but has never been explained. Here, we take advantage of the relative simplicity of this 'illusion' to explain it and contextual effects more generally, by using a simple Bayesian ideal observer model of the human visual ecology. We also use fMRI brain scans to identify the neural correlates of brightness without changing the spatial context of the stimulus, which has complicated the interpretation of related fMRI studies. RESULTS: Rather than modelling human vision directly, we use a Bayesian ideal observer to model human visual ecology. We show that the HK effect is a result of encoding the non-linear statistical relationship between retinal images and natural scenes that would have been experienced by the human visual system in the past. We further show that the complexity of this relationship is due to the response functions of the cone photoreceptors, which themselves are thought to represent an efficient solution to encoding the statistics of images. Finally, we show that the locus of the response to the relationship between images and scenes lies in the primary visual cortex (V1, if not earlier in the visual system, since the brightness of colours (as opposed to their luminance accords with activity in V1 as measured with fMRI. CONCLUSIONS: The data suggest that perceptions

  20. CA BrightStor

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    CA推出的BrightStor系列存储管理解决方案已经成为企业电子商务体系架构管理战略中举足轻重的组成部分。BrightStor是一整套企业级的智能化存储管理解决方案,定位在存储硬件设备和上层应用之间,通过各种集成化的产品和工具为驻留在企业任何位置的数据提供全方位的、有效的存储管理和保护。

  1. Bright Economic Prospects

    Institute of Scientific and Technical Information of China (English)

    Zhang Minqiu

    2004-01-01

    @@ India is expected to register an 8.2% growth rate for the 2003-04 fiscal year. The overall economic situation this year has been satisfactory despite the scaled down 6-6.5% growth rate for the new fiscal year due to oil price hikes, reduced monsoon volume and some 7% inflation. Judging from the following factors, bright prospects are in store for the country down the road.

  2. 5 CFR 531.243 - Promotion of a GM employee.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Promotion of a GM employee. 531.243... Promotion of a GM employee. (a) Upon promotion, an employee's status as a GM employee ends, as provided in § 531.241(b). (b) When an employee loses status as a GM employee because of a temporary promotion and...

  3. Regulating coexistence of GM and non-GM crops without jeopardizing economic incentives.

    Science.gov (United States)

    Demont, Matty; Devos, Yann

    2008-07-01

    The ongoing debate about the coexistence of genetically modified (GM) and non-GM crops in the European Union (EU) mainly focuses on preventive measures needed to keep the adventitious presence of GM material in non-GM products below established tolerance thresholds, as well as on issues covering questions of liability and the duty to redress the incurred economic harm once adventitious mixing in non-GM products has occurred. By contrast, the interplay between the economic incentives and costs of coexistence has attracted little attention. The current overemphasis on the technical aspects and cost of coexistence over its economic incentives might lead EU policy-makers to adopt too stringent and rigid regulations on coexistence. Therefore, we argue for flexible coexistence regulations that explicitly take into account the economic incentives for coexistence. Our arguments provide a timely and important framework for EU policy-makers, who are currently struggling to implement coherent coexistence regulations in all member states.

  4. Soybean GmMYB76,GmMYB92,and GmMYB177 genes confer stress tolerance in transgenic Arabidopsis plants

    Institute of Scientific and Technical Information of China (English)

    Yong Liao; Hong-Feng Zou; Hui-Wen Wang; Wan-Ke Zhang; Biao Ma; Jin-Song Zhang; Shou-Yi Chen

    2008-01-01

    MYB-type transcription factors contain the conserved MYB DNA-binding domain of approximately 50 amino acids and are involved in the regulation of many aspects of plant growth,development,metabolism and stress responses.From soybean plants,we identified 156 GmMYB genes using our previously obtained 206 MYB unigenes,and 48 were found to have full-length open-reading frames.Expressions of all these identified genes were examined,and we found that expressions of 43 genes were changed upon treatment with ABA,salt,drought and/or cold stress.Three GmMYB genes,GmMYB76,GmMYB92 and GmMYB177,were chosen for further analysis.Using the yeast assay system,GmMYB76 and GmMYB92 were found to have transactivation activity and can form homodimers.GmMYBI77 did not appear to have transactivation activity but can form heterodimers with GmMYB76.Yeast onehybrid assay revealed that all the three GmMYBs could bind to cis-elements TAT AAC GGT TTT TT and CCG GAA AAAAGG AT,but with different affinity,and GmMYB92 could also bind to TCT CAC CTA CC.The transgenic Arabidopsis plants overexpressing GmMYB76 or GmMYB177 showed better performance than the GmMYB92-transgenic plants in salt and freezing tolerance.However,these transgenic plants exhibited reduced sensitivity to ABA treatment at germination stage in comparison with the wild-type plants.The three GmMYB genes differentially affected a subset of stress-responsive genes in addition to their regulation of a common subset of stress-responsive genes.These results indicate that the three GmMYB genes may play differential roles in stress tolerance,possibly through regulation of stress-responsive genes.

  5. Low surface brightness galaxies

    Science.gov (United States)

    Vanderhulst, J. M.; Deblok, W. J. G.; Mcgaugh, S. S.; Bothun, G. D.

    1993-01-01

    A program to investigate the properties of low surface brightness (LSB) galaxies involving surface photometry in U, B, V, R, I, and H-alpha, HI imaging with the Westerbork Synthesis Radio Telescope (WSRT) and the very large array (VLA) and spectrophotometry of H2 regions in LSB galaxies is underway. The goal is to verify the idea that LSB galaxies have low star formation rates because the local gas density falls below the critical density for star formation, and to study the stellar population and abundances in LSB galaxies. Such information should help understanding the evolutionary history of LSB galaxies. Some preliminary results are reported.

  6. Assessing biosafety of GM plants containing lectins

    DEFF Research Database (Denmark)

    Poulsen, Morten; Pedersen, Jan W.

    2010-01-01

    of the lectins that are potentially useful for insect resistance will pose no health risk in genetically modified (GM) plants. Since some lectins are known for their toxicity to humans, the insertion of lectin genes in food crop plants will have to be assessed carefully. It is expected that in some cases...... there will be a need to perform animal tests of such GM plants in order to eliminate any uncertainties about potential safety issues for these plants. A 90-day study designed and optimized for this purpose is suggested as one way to cope with these uncertainties....

  7. GmWRKY27 interacts with GmMYB174 to reduce expression of GmNAC29 for stress tolerance in soybean plants.

    Science.gov (United States)

    Wang, Fang; Chen, Hao-Wei; Li, Qing-Tian; Wei, Wei; Li, Wei; Zhang, Wan-Ke; Ma, Biao; Bi, Ying-Dong; Lai, Yong-Cai; Liu, Xin-Lei; Man, Wei-Qun; Zhang, Jin-Song; Chen, Shou-Yi

    2015-07-01

    Soybean (Glycine max) is an important crop for oil and protein resources worldwide. The molecular mechanism of the abiotic stress response in soybean is largely unclear. We previously identified multiple stress-responsive WRKY genes from soybean. Here, we further characterized the roles of one of these genes, GmWRKY27, in abiotic stress tolerance using a transgenic hairy root assay. GmWRKY27 expression was increased by various abiotic stresses. Over-expression and RNAi analysis demonstrated that GmWRKY27 improves salt and drought tolerance in transgenic soybean hairy roots. Measurement of physiological parameters, including reactive oxygen species and proline contents, supported this conclusion. GmWRKY27 inhibits expression of a downstream gene GmNAC29 by binding to the W-boxes in its promoter region. The GmNAC29 is a negative factor of stress tolerance as indicated by the performance of transgenic hairy roots under stress. GmWRKY27 interacts with GmMYB174, which also suppresses GmNAC29 expression and enhances drought stress tolerance. The GmWRKY27 and GmMYB174 may have evolved to bind to neighbouring cis elements in the GmNAC29 promoter to co-reduce promoter activity and gene expression. Our study discloses a valuable mechanism in soybean for regulation of the stress response by two associated transcription factors. Manipulation of these genes should facilitate improvements in stress tolerance in soybean and other crops.

  8. GM-CSF and phorbol esters modulate GM-CSF receptor expression by independent mechanisms.

    Science.gov (United States)

    Brizzi, M F; Arduino, C; Avanzi, G C; Bussolino, F; Pegoraro, L

    1991-07-01

    Human granulocyte-macrophage colony-stimulating factor (GM-CSF) (0.1 nM) down-modulates its receptor in IL-3/GM-CSF dependent M-07e cells, in KG-1 cells and normal granulocytes, whereas phorbol esters 12-O-tetradecanoylphorbol-13-acetate (TPA) (2 nM) down-modulates the GM-CSF receptor in M-07e cells and granulocytes but not in KG-1 cells. As data analysis shows by nonlinear regression, the decreased binding ability depends on a reduction of the binding sites with no significant change of their dissociation constant. To gain insight into the mechanisms involved in the GM-CSF receptor regulation, we investigated the role of protein kinase C (PKC). GM-CSF, unlike TPA, was unable to activate PKC in all the cells studied. Moreover, unlike TPA, GM-CSF was still able to down-modulate its receptor in cells where PKC was inhibited by 1-(5-isoquinolonesulphonyl)-2-methylpiperazine (H7) and staurosporine or in cells where PKC was exhausted by prolonged incubation with 1 microM TPA. Finally, the receptor re-expression rate was accelerated by protein kinases inhibitors. These results, taken together, indicate the presence of a PKC-dependent and -independent down-modulation mechanism and a negative role of the endogeneous protein kinases in GM-CSF receptor re-expression.

  9. VITICULTURA Y POLÍTICA INTERNACIONAL: EL INTENTO DE REINCORPORAR A MENDOZA Y SAN JUAN A CHILE (1820-1835

    Directory of Open Access Journals (Sweden)

    PABLO LACOSTE

    2006-06-01

    Full Text Available Entre 1830 y 1835 algunos dirigentes de Mendoza y San Juan, provincias vitivinícolas, trataron de separarse de la República Argentina y regresar a Chile, tal como en la época colonial. Durante más de dos siglos, Mendoza y San Juan fueron parte del Corregimiento de Cuyo del Reino de Chile. Esta situación cambió desde 1776 con la creación del Virreinato del Río de la Plata. Después de la Revolución de 1810, Mendoza y San Juan formaron parte de la República Argentina. Pero algunos años después de la independencia, un grupo descontento con la acción y decisiones del gobierno de Buenos Aires, inició acciones orientadas a la secesión. Este artículo investiga las razones y motivaciones socioeconómicas de este grupoBetween 1830 and 1835 some leaders of Mendoza and San Juan, wine industry oriented provinces, attempted to withdrawal from Argentina Republic, and come back to Chile such as in colonial times. During more than two centuries, Mendoza and San Juan were members of Cuyo Province in Chile's Kingdom. This situation changed since 1776 because the creation of the River Plate Viceroyalty. After Revolution of 1810, Mendoza and San Juan took part of Argentina Republic. But some years after the independence, a group discontented with de action and decision of Buenos Aires government begun the action oriented to secession. This paper explores the socioeconomic reasons and motivation of this group

  10. High Density GEOSAT/GM Altimeter Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The high density Geosat/GM altimeter data south of 30 S have finally arrived. In addition, ERS-1 has completed more than 6 cycles of its 35-day repeat track. These...

  11. GM plants, farmers and the public

    DEFF Research Database (Denmark)

    Lassen, Jesper; Sandøe, Peter

    2009-01-01

    The controversy in Europe over genetically manipulated (GM) foods has been conceived largely as a conflict between a reluctant public and a more enthusiastic agri-food sector. As a result, the political focus has been on the public to the neglect of other actors, such as the farmers, whose willin...

  12. The loss from underutilizing GM technologies

    NARCIS (Netherlands)

    Zilberman, David; Kaplan, Scott; Wesseler, Justus

    2015-01-01

    This article introduces a framework based on a real-option approach to assess the economics of delaying the introduction of genetically modified (GM) technologies in agriculture due to concerns about their unintended effects (unexpected environmental side effects). We applied our framework to ana

  13. The GM foods debate in Europe

    DEFF Research Database (Denmark)

    Scholderer, Joachim

    2005-01-01

    The debate on genetically modified (GM) foods has been led on multiple levels in Europe, including such diverse frames of reference as economic policy and international trade, environmental risk, bioethics, consumer protection and food safety. The shifting frames of reference are traced over...

  14. Social stratification in a global successful activity: the case of wine industry in Mendoza (1995-2011

    Directory of Open Access Journals (Sweden)

    Mariana Heredia

    2013-12-01

    Full Text Available In order to contribute to the knowledge of social inequalities in contemporary Argentina, this article examines how the restructuring of the wine from Mendoza (which begun in the late eighties and consolidated in the year two thousand resulted in the restructuring of different socio-professional categories and their ties. The speed and depth of these transformations, in a relatively limited space and in an economic activity that is judged as a successful case of integration into the international market make Mendoza wine’s industry a privileged case to discuss social impact of agribusiness’ transnationalization

  15. La transición de periferia a frontera: mendoza en el siglo XVII

    Directory of Open Access Journals (Sweden)

    Margarita Gasc\\u00F3n

    2001-01-01

    Full Text Available El análisis de la evolución de Mendoza en el siglo XVII permite diferenciar las características de un asentamiento en la periferia de aquellas características que corresponden a una sociedad de frontera. Fundada en 1561 en la periferia imperio español en América a principios del siglo XVII, Mendoza era una comunidad con escasa población, con reducido comercio y de lento desarrollo urbano; todas características de las colonias periféricas. A lo largo de la primera parte del siglo XVII, sin embargo, Mendoza se fue configurando como una sociedad de frontera. Las causas de este devenir frontera se relacionan con la revuelta araucana y con las consecuencias del establecimiento de la frontera geográfico-militar en el río Biobio. El trabajo comienza con una revisión de los términos frontera y periferia tal como se encuentran empleados en los análisis de algunos autores representativos de la historiografía sobre fronteras para las Américas. Luego se reconstruye la evolución de periferia a frontera en Mendoza; un proceso que comenzó varias décadas después de su fundación en 1561. Tal fundación no estuvo guiada por la necesidad de consolidar o de proteger una zona de frontera, de modo que no fue fundada ni como presidio ni como misión, que son las típicas instituciones de frontera y que encontramos en numerosas fronteras del imperio español, como ser en la Florida y en el norte de México. A fines del siglo XVI Mendoza fue fundada como uno de los tantos asentamientos que permitirían a los españoles seguir avanzando en la conquista y colonización de nuevos territorios. Sin embargo, la revuelta araucana de 1598-1599 provocó el quiebre de tal desenvolvimiento de la conquista porque truncó la esperanza de una futura expansión española hacia el sur. Más allá del fiasco militar de la derrota de Curalaba, la rebelión nativa obligó a la coronaa establecer un ejército profesional de alrededor de 2.000 hombres, cuya permanencia

  16. A new species of Liolaemus (Reptilia: Squamata: Tropiduridae from Mendoza province, Argentina

    Directory of Open Access Journals (Sweden)

    Etheridge, Richard

    2001-05-01

    Full Text Available Una nueva especie del complejo Liolaemus darwinii es descrita para el centro de la provincia de Mendoza, Argentina. Se parece más a L. olongasta y L. laurenti en que los machos adultos tienen pigmento negro en el pliegue antehumeral y manchas escapulares que no son agrandadas. Difiere de estas especies en tener un cuerpo adulto menor, un número mayor de escamas en la mitad del cuerpo, una cola más corta y un mayor número de poros precloacales en machos, y un patrón ventral distinto en machos adultos. En el norte de su distribución se encuentra L. darwinii en el norte de la provincia de Mendoza y en la provincia de San Luis, y en el sur en el oeste de la provincia de La Pampa, en el noroeste de la provincia de Neuquén y en la provincia de Río Negro, pero se desconoce si estas poblaciones del norte y del sur de L. darwtnii están separadas por la distribución de la nueva especie. Análisis cladísticos basados en comportamiento, morfología y secuencias de DNA muestran filogenias conflictivas, pero concuerdan en que la nueva especie es un miembro del grupo boulengeri, con afinidades más cercanas a L. darwinii, L. olongasta y L. laurenti. A new species,of the Liolaemus darwinii complex is described from central Mendoza Province, Argentina. It most closely resembles L. olongasta and L. laurenti in that adult males have black pigment in the antehumeral fold and scapular spots that are not enlarged. It differs from these species in having a smaller adult body size, a higher number of midbody scales, a shorter tail, more precloacal pores in males, and a different adult male ventral body pattern. Its range is bordered by L. darwinii on the north in northern Mendoza and San Luis provinces, and on the south in western La Pampa and northwestern Neuquén and Río Negro provinces, but it is unknown whether these northern and southern populations of L. darwinii are separated by the range of the new species. Cladistic analyses based on behaviour

  17. Primer registro de Tityus trivittatus (Scorpiones: Buthidae en la provincia de Mendoza (Argentina

    Directory of Open Access Journals (Sweden)

    Florencia FERNÁNDEZ CAMPÓN

    2009-01-01

    Full Text Available En la siguiente nota se informa sobre el primer registro delescorpión Tityus trivittatus Kraepelin en la provincia de Mendoza en el Barrio Campo Papa, departamento de Godoy Cruz. T. trivittatus es dentro de nuestro país una de las especies de escorpiones con importancia médica, debido a que su veneno neurotóxico puede causar lesiones en el sistema nervioso y en algunos casos la muerte, particularmente en niños.

  18. Diagnosis of GM-1 gangliodosis in Cuba Comportamiento de la GM-1 gangliosidosis en Cuba.

    OpenAIRE

    Alina González-Quevedo Monteagudo; Claudina Zaldívar Muñoz; Sergio González García; Caridad Menéndez Saínz

    2007-01-01

    Background: GM-1 gangliosidosis is included in the group of lysosomal diseases and is characterized by a deficiency of the enzyme b-galactosidase, which as a consequence produces accumulation of GM1 ganglioside in nervous cells and galactosil oligosaccharides and products of keratan sulfate degradation in other tissues. Clinically this disease presents with an early psychomotor impairment, macular cherry red spots, facial dysmorphia, bone deformities and hepatospl...

  19. Epistemological depth in a GM crops controversy.

    Science.gov (United States)

    Hicks, Daniel J

    2015-04-01

    This paper examines the scientific controversy over the yields of genetically modified [GM] crops as a case study in epistemologically deep disagreements. Appeals to "the evidence" are inadequate to resolve such disagreements; not because the interlocutors have radically different metaphysical views (as in cases of incommensurability), but instead because they assume rival epistemological frameworks and so have incompatible views about what kinds of research methods and claims count as evidence. Specifically, I show that, in the yield debate, proponents and opponents of GM crops cite two different sets of claims as evidence, which correspond to two rival epistemological frameworks, classical experimental epistemology and Nancy Cartwright's evidence for use. I go on to argue that, even if both sides of the debate accepted Cartwright's view, they might still disagree over what counts as evidence, because evidence for use ties standards of evidence to what is sometimes called the "context of application."

  20. Safety of GM crops: compositional analysis.

    Science.gov (United States)

    Brune, Philip D; Culler, Angela Hendrickson; Ridley, William P; Walker, Kate

    2013-09-01

    The compositional analysis of genetically modified (GM) crops has continued to be an important part of the overall evaluation in the safety assessment program for these materials. The variety and complexity of genetically engineered traits and modes of action that will be used in GM crops in the near future, as well as our expanded knowledge of compositional variability and factors that can affect composition, raise questions about compositional analysis and how it should be applied to evaluate the safety of traits. The International Life Sciences Institute (ILSI), a nonprofit foundation whose mission is to provide science that improves public health and well-being by fostering collaboration among experts from academia, government, and industry, convened a workshop in September 2012 to examine these and related questions, and a series of papers has been assembled to describe the outcomes of that meeting.

  1. Differentiating the consumer benefits from labeling of GM food products

    NARCIS (Netherlands)

    Scatasta, S.; Wesseler, J.H.H.; Hobbs, J.E.

    2007-01-01

    Although recurrent evidence is found that consumers have different willingness to pay for GM and non-GM products, there is disagreement in the scientific community about the size of consumer benefits from GM labeling. In this article we use a theoretical model based on a standard constant elasticity

  2. Modelos historiográficos latinos en la Historia de la Guerra de Granada de Diego Hurtado de Mendoza

    OpenAIRE

    Abad Mellizo, Alejandro

    2016-01-01

    Se analizan los modelos que basándose en los historiadores latinos (fundamentalmente Salustio y Tácito) utiliza Diego Hurtado de Mendoza (1503-1575) al escribir su monografía acerca de la Rebelión de las Alpujarras (1568-1571).

  3. Plagas de la agricultura en Mendoza: la langosta en los comienzos de la vitivinicultura moderna (1890-1900

    Directory of Open Access Journals (Sweden)

    Eduardo Pérez Romagnoli

    2011-12-01

    Full Text Available El trabajo se refiere a la presencia de la langosta en Mendoza en los comienzos de la especialización vitivinícola, en la década de 1890. Comprende aspectos sobre su biogeografía, antecedentes del insecto en nuestro país, los primeros inventos nacionales para enfrentar sus ataques. Con relación a las invasiones de la Schistocerca americana en Mendoza, se indaga sobre la organización estatal y la participación de la sociedad para combatirla, incluyendo algunos problemas y daños causados en la agricultura.The study refers to the presence of locust in Mendoza at the beginning of wine specialization, in the decade of 1890. It includes aspects on biogeography, precedents of the insect in our country, and first national inventions to face its assaults. In relation to invasions of Schistocercaamericana in Mendoza, the study researches on state organization and social participation to attack the plague, including some problems and damages caused in agriculture.

  4. Antonio de Mendoza; First Viceroy of Mexico. The Tinker Pamphlet Series for the Teaching of Mexican American Heritage.

    Science.gov (United States)

    Miller, Hubert J.

    As Mexico's first viceroy, Antonio de Mendoza's most noteworthy achievement was his laying the basis of colonial government in New Spain which continued, with modifications, for 300 years. Although he was lenient in dealing with the shortcomings of his Indian and Spanish subjects, he took a firm stand in dealing with the rebellious Indians in the…

  5. Water in the Mendoza, Argentina, food processing industry: water requirements and reuse potential of industrial effluents in agriculture

    Directory of Open Access Journals (Sweden)

    Alicia Elena Duek

    2016-04-01

    Full Text Available This paper estimates the volume of water used by the Mendoza food processing industry considering different water efficiency scenarios. The potential for using food processing industry effluents for irrigation is also assessed. The methodology relies upon information collected from interviews with qualified informants from different organizations and food-processing plants in Mendoza selected from a targeted sample. Scenarios were developed using local and international secondary information sources. The results show that food processing plants in Mendoza use 19.65 hm3 of water per year; efficient water management practices would make it possible to reduce water use by 64%, i.e., to 7.11 hm3. At present, 70% of the water is used by the fruit and vegetable processing industry, 16% by wineries, 8% by mineral water bottling plants, and the remaining 6% by olive oil, beer and soft drink plants. The volume of effluents from the food processing plants in Mendoza has been estimated at 16.27 hm3 per year. Despite the seasonal variations of these effluents, and the high sodium concentration and electrical conductivity of some of them, it is possible to use them for irrigation purposes. However, because of these variables and their environmental impact, land treatment is required.

  6. How Bright Is the Sun?

    Science.gov (United States)

    Berr, Stephen

    1991-01-01

    Presents a sequence of activities designed to allow eighth grade students to deal with one of the fundamental relationships that govern energy distribution. Activities guide students to measure light bulb brightness, discover the inverse square law, compare light bulb light to candle light, and measure sun brightness. (two references) (MCO)

  7. Development of Compact 2K GM Cryocoolers

    Science.gov (United States)

    Xu, Mingyao; Bao, Qian; Tsuchiya, Akihiro; Li, Rui

    A compact 2K Gifford-McMahon (GM) cryocooler has been developed for cooling electronic devices, such as Superconducting Single Photo Detectors (SSPD). The heat exchangers, regenerators are optimized with the numerical simulation method developed for 4K GM cryocoolers. After optimizing, the cylinder length is reduced by 85 mm compared with a commercial 0.1W 4K GM cryocooler. With no load on the second stage, a temperature of about 2.1 K has been achieved. With 1 W and 20 mW heat load, the temperature is 44.4 K at the first stage and 2.23 K at the second stage with an input power of about 1.1 kW. And also, it is found that the temperature oscillation decreases as the average temperature decreases. A temperature oscillation of about ±20 mK has been achieved. The object of the project, target specification, and a summary of experiment results will also be introduced in this paper.

  8. Diezmos, producción agraria y mercados: Mendoza y Cuyo, 1710-1830

    Directory of Open Access Journals (Sweden)

    Juan Carlos Garavaglia

    2007-12-01

    Full Text Available En este trabajo exponemos los primeros resultados de una investigación destinada a analizar la estructura agraria de la región del oasis mendocino desde los años cincuenta del siglo XVIII a 1861. El estudio está enfocado sobre todo en Mendoza, pero abarca también el resto de la región cuyana. Centrado en especial sobre la serie de diezmos eclesiásticos entre 1710 y 1830, el trabajo deja ver la influencia de los ciclos climáticos en la producción agraria, como también los cambios en los mercados para los productos cuyanos durante ese largo siglo, mostrando de qué modo hay a fines del período una reorientación productiva y mercantil.This work expounds the initial results of research that analyzes agrarian structures in the region of the Mendozan Oasis from the 1750s to 1861. The study is centered in Mendoza, but it also includes the rest of the Cuyana region. By examining an archival series of ecclesiastical tithes between 1710 and 1830, the article brings into focus the influence of climatic cycles on agrarian production in addition to the changes in the market for Cuyano products over this long century. By so doing, it demonstrates how a productive and mercantile reorientation had taken place by the end of the period.

  9. Domestic wastewater treatment in waste stabilization ponds for irrigation in Mendoza, Argentina: policies and challenges.

    Science.gov (United States)

    Vélez, O R; Fasciolo, G E; Bertrano, A V

    2002-01-01

    Arid areas call for imaginative water management solutions to avoid the dangers of water shortages. Growing demands of water for domestic and industrial uses decrease the availability of water for agriculture. It therefore becomes necessary to set up a policy for the use of domestic effluents. For the province of Mendoza, Argentina, with 1,500,000 inhabitants, a master plan was designed as of 1991 for the treatment of domestic effluents and subsequent disposal for irrigation. The guidelines set up by WHO for the use of wastewater in agricultural applications were taken into consideration. At present, the Province of Mendoza has available projects which are either complete, in execution or in the bidding process, entailing secondary treatment capacity with reuse of 320,000 cubic metres/day and an estimated possible irrigation area of 10,000 hectares. With this infrastructure, some strategic lines of action are recommended to establish a policy for the agricultural use of wastewater: (a) to program the use of treated wastewater to avoid discharges to irrigation flows; (b) to develop an institutional scheme for the efficient and safe use of these waters; and (c) develop scientific and technologic know-how to accompany the updated policies.

  10. ARTESANOS, TRABAJADORES METALÚRGICOS Y VITIVINICULTURA MODERNA EN MENDOZA ARGENTINA (1885-1930

    Directory of Open Access Journals (Sweden)

    Eduardo Pérez Romagnoli

    2005-12-01

    Full Text Available A fines del siglo XIX, la reconversión económica hacia la vitivinicultura moderna, liderada por un sector del grupo social dominante, generaba cambios profundos en Mendoza –al pie de los Andes y a 1000 km de Buenos Aires- en los que los inmigrantes europeos mediterráneos desempeñaron un papel central. Se produjo un rápido aumento de la superficie con viñedo -acompañada por un aumento de la red que distribuía el escaso recurso hídrico- y la difusión de la producción industrial de vino en el oasis norte, irrigado por los ríos Mendoza y Tunuyán. A principios del siglo XX, el proceso era también notable en el oasis sur, conformado por los ríos Diamante y Atuel. Según el Segundo Censo Nacional, en 1914, la superficie con viñedo alcanzaba las 70 mil hectáreas y había registradas más de 1300 bodegas; pero su capacidad de producción era muy contrastada

  11. Sauropod and theropod dinosaur tracks from the Upper Cretaceous of Mendoza (Argentina): Trackmakers and anatomical evidences

    Science.gov (United States)

    González Riga, Bernardo Javier; Ortiz David, Leonardo Daniel; Tomaselli, María Belén; dos Anjos Candeiro, Carlos Roberto; Coria, Juan Pedro; Prámparo, Mercedes

    2015-08-01

    New findings of dinosaur ichnites from Agua del Choique section (Mendoza Province, Argentina) provides ichnological and anatomical information about the Cretaceous sauropods and theropods. Around 330 tracks distributed in six footprint levels were identified in this area, one of most important of South America. Two ichnocenoses are located in different paleoenvironmental contexts. In the Anacleto Formation (early Campanian) around 20 titanosaurian tracks were found in floodplain and ephemeral channel deposits. Herein, one pes track shows three claw impressions and this is congruent to two new titanosaur specimens recently discovered in Mendoza Province that have articulated and complete pedes. In this context, for the first time to titanosaurs, ichnological evidences are supported by skeletal elements. In the Loncoche Formation (late Campanian-early Maastrichtian) titanosaurian tracks of Titanopodus mendozensis are abundant (around 310 tracks) and were produced by titanosaurs that walked in a very wet substrate of tidally dominated deltas related with the first Atlantic transgression for northern Patagonia. In this facies association, three different trydactl tracks indicate the presence of small theropods (1-2 m long), expanding the knowledge about the faunistic components that lived in these marine marginal environments.

  12. Paleozoogeography of the Wine Mouse (Akodon oenos & Late Holocene Paleoenvironments in South-Central Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Fernando Julián Fernández

    2011-02-01

    Full Text Available Cranial remains of the wine mouse (Akodon oenos are documented from an archaeological site in south-central Mendoza, Argentina (Agua de La Mula, 35º22' S, 68º15' W, which dates to the end of the late Holocene (1610 ± 60; 1260 ± 60; 1000 ± 50 C14 yr B.P.. The taxonomic status of this small rodent is currently being assessed, but these remains represent the first fossil record for the morphotaxon A. oenos. The species’ present distribution is restricted to a few records from Mendoza province. Analysis of the remains supports paleoenvironmental reconstruction using the small mammal assemblage recovered from this site. From the late Holocene into modernity temperature decreased and winter precipitation increased, resulting in advance of Patagonian steppe grading with altitude into Monte desert. Holocene climatic conditions may explain the relatively late human occupation of ecologically marginal environments in this region, which probably favored effective human occupation of the Payunia region at sites such as Agua de La Mula between 1600 and 1000 years B.P.

  13. Vinos de Mendoza : relación precio en góndola versus calidad en degustación a ciegas

    OpenAIRE

    Antoniolli, Ester R.; Alturria, Laura V.; Ceresa, Alejandro M.; Solsona, Juan E.; de Winter, Patricia; Galiotti, Hugo; Fonzar, Alfredo

    2011-01-01

    Cuando un posible consumidor de vinos decide su compra, lo hace influenciado por factores relacionados no sólo con la calidad del producto sino también con el conocimiento que tiene de la marca. Esta investigación se inició con un mapeo de vinos ofrecidos en puntos de venta minorista del Gran Mendoza, para luego realizar una degustación a ciegas con panelistas de la provincia de Mendoza, de sectores de ...

  14. The GM2 gangliosidoses databases: allelic variation at the HEXA, HEXB, and GM2A gene loci.

    Science.gov (United States)

    Cordeiro, P; Hechtman, P; Kaplan, F

    2000-01-01

    The GM2 gangliosidoses are a group of recessive disorders characterized by accumulation of GM2 ganglioside in neuronal cells. The genes responsible for these disorders are HEXA (Tay-Sachs disease and variants), HEXB (Sandhoff disease and variants), and GM2A (AB variant of GM2 gangliosidosis). We report the establishment of three relational locus-specific databases recording allelic variation at the HEXA, HEXB, and GM2A genes and accessed at the GM2 gangliosidoses home page (http://data.mch.mcgill.ca/gm2-gangliosidoses). Submission forms are available for the addition of new mutations to the databases. The databases are available online for users to search and retrieve information about specific alleles by a number of fields describing mutations, phenotypes, or author(s).

  15. Impact of GM crops on biodiversity.

    Science.gov (United States)

    Carpenter, Janet E

    2011-01-01

    The potential impact of GM crops on biodiversity has been a topic of interest both in general as well as specifically in the context of the Convention on Biological Diversity. Agricultural biodiversity has been defined at levels from genes to ecosystems that are involved or impacted by agricultural production (www.cbd.int/agro/whatis.shtml). After fifteen years of commercial cultivation, a substantial body of literature now exists addressing the potential impacts of GM crops on the environment. This review takes a biodiversity lens to this literature, considering the impacts at three levels: the crop, farm and landscape scales. Within that framework, this review covers potential impacts of the introduction of genetically engineered crops on: crop diversity, biodiversity of wild relatives, non-target soil organisms, weeds, land use, non-target above-ground organisms, and area-wide pest suppression. The emphasis of the review is peer-reviewed literature that presents direct measures of impacts on biodiversity. In addition, possible impacts of changes in management practises such as tillage and pesticide use are also discussed to complement the literature on direct measures. The focus of the review is on technologies that have been commercialized somewhere in the world, while results may emanate from non-adopting countries and regions. Overall, the review finds that currently commercialized GM crops have reduced the impacts of agriculture on biodiversity, through enhanced adoption of conservation tillage practices, reduction of insecticide use and use of more environmentally benign herbicides and increasing yields to alleviate pressure to convert additional land into agricultural use.

  16. A Colonial Cacicazgo: the Mendozas of Seventeenth-Century Tepexí de la Seda

    Directory of Open Access Journals (Sweden)

    Rik Hoekstra

    2010-10-01

    Full Text Available The cacicazgo, or indigenous lordship, was a pivotal institution in colonial Mexican Indian pueblos. Caciques, or Indian nobles, played a role, both in the largely indigenous world of the pueblo and in the regional economy that was dominated by Spaniards. This subject of this essay is the analysis of the evolution and daily operation and of a cacicazgo from the Indian settlement of Tepexí de la Seda near the city of Puebla de los Ángeles and the life of its caciques in the sixteenth and seventeenth centuries. In the sixteenth century the cacicazgo was in upheaval because of discord between the cacicazgos and their dependent Indians. A number of long-running accounts from the 1620s record in detail the daily operations of the cacicazgo of Doña Ana de Santa Bárbara of the Mendoza family, thus illustrating how caciques negotiated their positions and coped with their lives and the changes in it.   Resumen: Un cacicazgo colonial: los Mendoza de Tepexí de la Seda en el siglo 17 El cacicazgo, o señorío indígena, fue una institución fundamental en los pueblos indios de México colonial. Los caciques, o nobles indígenas, desempeñaron un papel tanto en el mundo en gran parte indígena del pueblo y en la economía regional dominada entonces por los españoles. El tema de este ensayo es el análisis de la evolución y operación cotidianas de un cacicazgo del asentamiento indígena de Tepexí de la Seda cerca de la ciudad de Puebla de los Ángeles y la vida de sus caciques en los siglos 16 y 17. En el siglo 16, el cacicazgo vivió tiempos convulsos debido a los conflictos entre los caciques y sus dependientes indios. Varias extensas cuentas de los años veinte del siglo 17 registran en detalle las operaciones diarias del cacicazgo de doña Ana de Santa Bárbara, de la familia Mendoza, mostrando así cómo negociaban los caciques sus posiciones y se adaptaban a los cambios en sus vidas.

  17. Chronology of Late Pleistocene glacier advances in the Rı´o Mendoza Valley, Argentina

    Science.gov (United States)

    Espizua, Lydia E.

    1999-10-01

    The Rı´o Mendoza valley at 33°S latitude has been repeatedly invaded by glaciers during the Late Pleistocene. Relative-age criteria, U-series ages, and thermoluminescense dating, permitted the glacial deposits to be separated into three mappable units, each less extensive than its predecessor, designed from oldest to youngest, Penitentes, Horcones and Almacenes drifts. Previous studies have shown that during the Penitentes advance the glacier system terminated at 2500 m, while during the subsequent Horcones advance, ice terminated at 2750 m and the Almacenes moraine reached 3250 m. A travertine layer overlying Penitentes till yielded 230Th/ 232Th ages of 38,300±5300, 24,200±2000 and 22,800±3100 yr B.P. This study focuses on dating interstadial sediments in the upper Rı´o Mendoza valley in order to constrain the ages of the drifts. A date was obtained from a composite stratigraphic profile based on exposures along the east side of the Rı´o de los Horcones Inferior valley, a tributary of the Rı´o de las Cuevas valley, which includes the Penitentes and Horcones tills separated by nonglacial sediments (silt, fine sand and clay), and are interpreted as representing the Penitentes-Horcones nonglacial interval. The fine quartz grains (4-11 μm) of these sediments were TL dated as 31,000±3100 yr. All these dates, which are minimum ages for the underlying Penitentes till, imply that the Penitentes ice advanced prior to the last glacial maximum and sometime before ca. 40,000 years ago. A minimum date for Horcones till comes from an exposure on the east side of the Rı´o de los Horcones Inferior valley where the Horcones and Almacenes tills are separated by sediments of nonglacial origin. The fine quartz grains (4-11 μm) of these sediments have been dated by TL as 15,000±2100 years ago. Almacenes till is inferred to represent a standstill or a readvance that occurred late during the Horcones glacier advance. These dates imply that the Penitentes advance may

  18. Aftereffect of Adaptation to Illusory Brightness

    OpenAIRE

    Xinguang Cao; Hiroyuki Ito

    2011-01-01

    Several figures are known to induce illusory brightness. We tested whether adaptation to illusory brightness produced an aftereffect in brightness. After viewing a gray square area having illusory brightness (e.g., due to brightness contrast or illusory contours) for ten seconds, the illusion-inducing surround vanished. After three seconds, subjects reported whether the square area was seen as brighter than, darker than, or the same brightness as a control gray square area. The luminance of t...

  19. Characterization of Rhizobacteria from field grown Genetically Modified (GM and non-GM maizes

    Directory of Open Access Journals (Sweden)

    Emmanuel Wihkochombom Bumunang

    2014-02-01

    Full Text Available This study was done to examine the rhizobacteria from field grown Genetically Modified (GM maize and its non-GM counterpart. Rhizospheric soil samples were collected at 30 days after sowing (DAS and at post-harvest from two experimental fields in Gauteng, South Africa. Total rhizobacteria (cfu/g in GM and non-GM soil samples was not significantly different across the different media 30 DAS and at post-harvest. Rhizobacterial isolates obtained were biochemically characterized using the analytical profile index. Species of Pseudomonas, Aeromonas, Sphingomonas, Burkholderia, Stenotrophomonas, Achromobacter, Ewingella and Bacillus were screened in vitro for plant growth promoting traits such as, ammonia production, catalase activity, indole acetic acid production, phosphate solubilisation, hydrogen cyanide production and antifungal activity. All the 32 rhizobacterial strains tested in this study were positive for catalase activity, ammonia production and IAA production; 90.6% were positive for phosphate solubilisation, 34.3% for indicate antifungal activity but none for hydrogen cyanide production. These findings contributed to the quest for potential biofertilizers and biocontrol agents for sustainable agriculture.

  20. Geofisica del cuerpo ultramáfico de la mina Salamanca, provincia de Mendoza

    Directory of Open Access Journals (Sweden)

    J. Kostadinoff

    2004-03-01

    Full Text Available La faja de rocas máficas-ultramáficas de la Cordillera Frontal de Mendoza es considerada como una ofiolita desmembrada. La presencia en las rocas ultramáficas serpentinízadas portadoras de mineralizaciónes de talco, sulfuros polimetálicos y de elementos del grupo del platino (EGP constituyen un atractivo para la realización de prospecciones geofísicas. La metodología de trabajo consistió en medir una red de estaciones geofísicas (gravimetría y magnetometría, en el área de la mina Salamanca. Los resultados permitieron evaluar las reservas de talco y calibrar un modelo de prospección geofísica para los sulfuros polimetálicos presentes en la faja de rocas máficas - ultramáficas de la Cordillera Frontal.

  1. Nueva ruralidad en territorios periféricos: los productores caprinos del noreste de Mendoza (Argentina

    Directory of Open Access Journals (Sweden)

    Laura María Torres

    2008-07-01

    Full Text Available Lately, several authors have been analyzing the changes in rural areas triggered by globalization. The concepts of new rurality and pluriactivity have allowed progress along these lines, highlighting the new difficulties facing the most vulnerable sectors. This study explores the transformation of peripheral rural territories in Mendoza (Argentina, particularly those that have been thought of as isolated and traditional. This research develops from a case study, combines quantitative and qualitative methods, and takes the production undertakings happening in those lands as units of analysis. Production and economic situations of the past are compared to those in the present. The tendency toward pluriactivity is here considered as a response to the new conditions, and also as an expression of the process of articulation with the capitalist system.

  2. Functional analysis of structurally related soybean GmWRKY58 and GmWRKY76 in plant growth and development.

    Science.gov (United States)

    Yang, Yan; Chi, Yingjun; Wang, Ze; Zhou, Yuan; Fan, Baofang; Chen, Zhixiang

    2016-08-01

    WRKY transcription factors constitute a large protein superfamily with a predominant role in plant stress responses. In this study we report that two structurally related soybean WRKY proteins, GmWRKY58 and GmWRKY76, play a critical role in plant growth and flowering. GmWRKY58 and GmWRKY76 are both Group III WRKY proteins with a C2HC zinc finger domain and are close homologs of AtWRKY70 and AtWRKY54, two well-characterized Arabidopsis WRKY proteins with an important role in plant responses to biotic and abiotic stresses. GmWRKY58 and GmWRKY76 are both localized to the nucleus, recognize the TTGACC W-box sequence with a high specificity, and function as transcriptional activators in both yeast and plant cells. Expression of GmWRKY58 and GmWRKY76 was detected at low levels in roots, stem, leaves, flowers, and pods. Expression of the two genes in leaves increased substantially during the first 4 weeks after germination but steadily declined thereafter with increased age. To determine their biological functions, transgenic Arabidopsis plants were generated overexpressing GmWRKY58 or GmWRKY76 Unlike AtWRKY70 and AtWRKY54, overexpression of GmWRKY58 or GmWRKY76 had no effect on disease resistance and only small effects on abiotic stress tolerance of the transgenic plants. Significantly, transgenic Arabidopsis plants overexpressing GmWRKY58 or GmWRKY76 flowered substantially earlier than control plants and this early flowering phenotype was associated with increased expression of several flowering-promoting genes, some of which are enriched in W-box sequences in their promoters recognized by GmWRKY58 and GmWRKY76. In addition, virus-induced silencing of GmWRKY58 and GmWRKY76 in soybean resulted in stunted plants with reduced leaf expansion and terminated stem growth. These results provide strong evidence for functional divergence among close structural homologs of WRKY proteins from different plant species.

  3. Diagnosis of GM-1 gangliodosis in Cuba Comportamiento de la GM-1 gangliosidosis en Cuba.

    Directory of Open Access Journals (Sweden)

    Claudina Zaldívar Muñoz

    Full Text Available Background: GM-1 gangliosidosis is included in the group of lysosomal diseases and is characterized by a deficiency of the enzyme b-galactosidase, which as a consequence produces accumulation of GM1 ganglioside in nervous cells and galactosil oligosaccharides and products of keratan sulfate degradation in other tissues. Clinically this disease presents with an early psychomotor impairment, macular cherry red spots, facial dysmorphia, bone deformities and hepatosplenomegaly. It has a hereditary autosomic-recessive pattern. Objective: To determine of β-galactosidase acid activity in patients with suspicion of GM-1 gangliosidosis. Methods: From 1986 to 2006, 1851 patients have been received in our laboratory from all the country, of which 851 had the diagnostic impression of GM-1 gangliosidosis. In samples from patients, parents and controls, the activity of leukocyte b-galactosidase was determined by a fluorimetric technique (metilumbelliferil derivatives and leukocyte protein level was determined according to Lowry’s method. Results and conclusions: The diagnosis of GM-1 gangliosidosis was attained in 11 patients, and the enzymatic activity was three times lower in patients with respect to their parents and five times lower with respect to controls. The enzymatic activity was not related with gender or age.
    Fundamento: La GM1 gangliosidosis se encuentra incluida dentro del grupo de las enfermedades lisosomales. Se caracteriza por la deficiencia de la enzima b-galactosidasa, lo cual tiene como consecuencia la acumulación del gangliosido GM1 en células nerviosas y galactosil oligosacáridos y productos de degradación de keratán sulfato en otros tejidos. Clínicamente esta enfermedad se expresa por un temprano deterioro psicomotor, mancha rojo-cereza en la mácula, dismorfia facial, deformidades óseas y hepatoesplenomegalia. Se

  4. Regional climate change scenarios applied to viticultural zoning in Mendoza, Argentina.

    Science.gov (United States)

    Cabré, María Fernanda; Quénol, Hervé; Nuñez, Mario

    2016-09-01

    Due to the importance of the winemaking sector in Mendoza, Argentina, the assessment of future scenarios for viticulture is of foremost relevance. In this context, it is important to understand how temperature increase and precipitation changes will impact on grapes, because of changes in grapevine phenology and suitability wine-growing regions must be understood as an indicator of climate change. The general objective is to classify the suitable areas of viticulture in Argentina for the current and future climate using the MM5 regional climate change simulations. The spatial distribution of annual mean temperature, annual rainfall, and some bioclimatic indices has been analyzed for the present (1970-1989) and future (2080-2099) climate under SRES A2 emission scenario. In general, according to projected average growing season temperature and Winkler index classification, the regional model estimates (i) a reduction of cool areas, (ii) a westward and southward displacement of intermediate and warm suitability areas, and (iii) the arise of new suitability regions (hot and very hot areas) over Argentina. In addition, an increase of annual accumulated precipitation is projected over the center-west of Argentina. Similar pattern of change is modeled for growing season, but with lower intensity. Furthermore, the evaluation of projected seasonal precipitation shows a little precipitation increase over Cuyo and center of Argentina in summer and a little precipitation decrease over Cuyo and northern Patagonia in winter. Results show that Argentina has a great potential for expansion into new suitable vineyard areas by the end of twenty-first century, particularly due to projected displacement to higher latitudes for most present suitability winegrowing regions. Even though main conclusions are based on one global-regional model downscaling, this approach provides valuable information for implementing proper and diverse adaptation measures in the Argentinean viticultural

  5. Regional climate change scenarios applied to viticultural zoning in Mendoza, Argentina

    Science.gov (United States)

    Cabré, María Fernanda; Quénol, Hervé; Nuñez, Mario

    2016-09-01

    Due to the importance of the winemaking sector in Mendoza, Argentina, the assessment of future scenarios for viticulture is of foremost relevance. In this context, it is important to understand how temperature increase and precipitation changes will impact on grapes, because of changes in grapevine phenology and suitability wine-growing regions must be understood as an indicator of climate change. The general objective is to classify the suitable areas of viticulture in Argentina for the current and future climate using the MM5 regional climate change simulations. The spatial distribution of annual mean temperature, annual rainfall, and some bioclimatic indices has been analyzed for the present (1970-1989) and future (2080-2099) climate under SRES A2 emission scenario. In general, according to projected average growing season temperature and Winkler index classification, the regional model estimates (i) a reduction of cool areas, (ii) a westward and southward displacement of intermediate and warm suitability areas, and (iii) the arise of new suitability regions (hot and very hot areas) over Argentina. In addition, an increase of annual accumulated precipitation is projected over the center-west of Argentina. Similar pattern of change is modeled for growing season, but with lower intensity. Furthermore, the evaluation of projected seasonal precipitation shows a little precipitation increase over Cuyo and center of Argentina in summer and a little precipitation decrease over Cuyo and northern Patagonia in winter. Results show that Argentina has a great potential for expansion into new suitable vineyard areas by the end of twenty-first century, particularly due to projected displacement to higher latitudes for most present suitability winegrowing regions. Even though main conclusions are based on one global-regional model downscaling, this approach provides valuable information for implementing proper and diverse adaptation measures in the Argentinean viticultural

  6. Geophysical characterization of circular structures in Chubut and Mendoza (Argentina): Impact vs. Volcanism

    Science.gov (United States)

    Prezzi, C.; Orgeira, M. J.; Risso, C.; Acevedo, R.; Ponce, F.; Nullo, F.; Martinez, O.; Rabassa, J.; Margonari, L.; Corbella, H.

    2013-05-01

    This work focuses on two main objectives. One of them is to provide information to discern the genesis of the circular structures present in Bajada del Diablo (Chubut, Argentina) considered as impact craters, and the other one is to contribute to a better knowledge of the circular structures located in the volcanic fields of Llancanelo and Payunia (Mendoza, Argentina). Chubut circular structures have been attributed to the collision of an extraterrestrial body, possibly an asteroid. However, doubts persist about their genesis because of the lack of direct geological evidences. Since detailed geomorphological studies have ruled out an origin by wind deflation, the prevailing alternative hypothesis attributes these circular structures to a volcanic process. On the other hand, the study of the volcanic fields of Payunia and Llancanelo (Mendoza) will contribute to the knowledge of the mechanics of hydromagmatic processes in the area, and the origin of circular structures morphologically similar to those located in Chubut. In the Payunia volcanic field at least 27 cones with evidences of hydromagmatism, in a field of more than 800 pure magmatic cones, have been recognized. This study tries to determine if a relationship between the observed volcanic circular structures and participation of water during the eruption exists. Magnetic and gravity field surveys of the circular volcanic structures in Llancanelo and Payunia volcanic fields were performed in order to determine their relationship with the type of eruption. Electromagnetic, magnetic and gravity field surveys were also carried out in Chubut circular structures. The comparative analysis of geological and geophysical results obtained in the circular structures of Chubut and those obtained in the circular structures in the volcanic areas of Llancanelo and Payunia suggest an impact origin for the circular structures of Chubut.

  7. Extensive Analysis of GmFTL and GmCOL Expression in Northern Soybean Cultivars in Field Conditions.

    Directory of Open Access Journals (Sweden)

    Guangyu Guo

    Full Text Available The FLOWERING LOCUS T (FT gene is a highly conserved florigen gene among flowering plants. Soybean genome encodes six homologs of FT, which display flowering activity in Arabidopsis thaliana. However, their contributions to flowering time in different soybean cultivars, especially in field conditions, are unclear. We employed six soybean cultivars with different maturities to extensively investigate expression patterns of GmFTLs (Glycine max FT-like and GmCOLs (Glycine max CO-like in the field conditions. The results show that GmFTL3 is an FT homolog with the highest transcript abundance in soybean, but other GmFTLs may also contribute to flower induction with different extents, because they have more or less similar expression patterns in developmental-, leaf-, and circadian-specific modes. And four GmCOL genes (GmCOL1/2/5/13 may confer to the expression of GmFTL genes. Artificial manipulation of GmFTL expression by transgenic strategy (overexpression and RNAi results in a distinct change in soybean flowering time, indicating that GmFTLs not only impact on the control of flowering time, but have potential applications in the manipulation of photoperiodic adaptation in soybean. Additionally, transgenic plants show that GmFTLs play a role in formation of the first flowers and in vegetative growth.

  8. Danish farmer’s perception of GM-crops

    DEFF Research Database (Denmark)

    Søndergaard, Janus; Pedersen, Søren Marcus; Gylling, Morten

    2005-01-01

    This paper presents a study of 185 farmer’s perception of GM-crops in Denmark. The respondent’s attitude to GM-crops mainly reflects a conservative view of the adoption of GM-crops. Among farmers only the exciting crops in rotation is seen as their future potential GM-crops. Findings from...... this study show that more the 60 pct do not expect any or less than 13 EUR increase in gross margins on their farms from adopting GM-crops. This assessment illustrates that the farmers regard the GM-crops more as a way of ‘staying in business” than a technology to increase their profits....

  9. Darwin's observation in South America: what did he find at agua de la zorra, Mendoza province? Las observaciones de Darwin en Sudamérica: ¿Qué encontró en Agua de la Zorra, provincia de Mendoza?

    OpenAIRE

    Stella Poma; Vanesa D Litvak; Magdalena Koukharsky; E. Beatriz Maisonnave; Sonia Quenardelle

    2009-01-01

    Scarcely 23 km from Uspallata, along the track of the old national highway 7, lies the district of Agua de la Zorra, in Mendoza province in western Argentina. Charles Darwin visited the area during his South American journeys in the 19th century and discovered a geological sequence that contained a paleoflora never described before. The flora includes an important number of species, particularly what is considered a small conifer forest with many silicified trunks still in life position. Darw...

  10. Minerales de mena del depósito epitermal de baja sulfuración Don Sixto, Mendoza Ore minerals from Don Sixto, a low sulfidation epithermal deposit from Mendoza

    Directory of Open Access Journals (Sweden)

    Ana Cecilia Mugas Lobos

    2012-03-01

    Full Text Available El proyecto minero Don Sixto es un depósito epitermal de baja sulfuración de Au-Ag, ubicado en el bloque de San Rafael, en el SE de la provincia de Mendoza. En este depósito, cuyo recurso aurífero es próximo a las 900.000 onzas, se ha identificado una asociación de minerales de metales preciosos que incluye: uytenbogaardtita, stromeyerita, naumannita, acantita, polibasita, stützita y cervelleita. Estos minerales son escasos y se encuentran frecuentemente asociados a oro y plata de variable fineza, diseminados en vetas de cuarzo hidrotermal y en unidades volcánicas-piroclásticas de los Grupos Choiyoi y El Portillo. En este depósito se encuentra abundante pirita, con cantidades menores de arsenopirita, calcopirita, esfalerita, magnetita, hematita y, en forma subordinada, pirrotina, galena, marcasita, bornita y boulangerita, junto con calcosina, digenita y covellina. La presencia de uytenbogaardtita, stützita, cervelleita y polibasita constituye la primera mención de estos minerales para la provincia de Mendoza.The Don Sixto mining project is a low sulfidation Au-Ag deposit, with a gold resource close to 900,000 ounces, located in the San Rafael Massif, in the SE of Mendoza province. Recently, it was found a precious-metal mineral association including uy-tenbogaardtite, stromeyerite, naumannite, acanthite, polybasite, stützite and cervelleite. These minerals are scarce and are commonly related to gold and silver of variable fineness, disseminated in hydrothermal quartz veins and volcanic-pyroclastic rock units from the Choiyoi and El Portillo Group. The most common mineral is pyrite associated with subordinated arsenopyrite, chalcopyrite, sphalerite, magnetite and hematite; lesser amounts of pyrrhotite, galena, marcasite, bornite, boulangerite, chalcocite, digenite and covellite were also recognized. This is the first mention in Mendoza province for uytenbogaardtite, stützite, cervelleite and polybasite.

  11. The cost of segregating GM canola: A case study

    OpenAIRE

    Hatwell, Bronwyn; Pluske, Johanna M.

    2004-01-01

    The Gene Technology Regulator's approval of Bayer CropScience's genetically modified (GM) canola variety, InVigor, and Monsanto's Roundup Ready, means that the commercial planting of Australia's first GM food crop is imminent. Under such circumstances, for Australia to continue marketing non-GM canola and comply with worldwide labelling requirements segregation must be implemented. This study investigates the cost effectiveness of three possible segregation methods. In considering each of the...

  12. 大豆(Glycinemax)GmDREB5互作蛋白GmUBC13的特性及功能%Characteristics and Function of a GmDREB5-Interacting Protein GmUBC13 in Soybean

    Institute of Scientific and Technical Information of China (English)

    徐东北; 马有志; 陈明; 陈耀锋; 于月华; 韩巧玲; 马亚男; 高世庆; 田野; 徐兆师; 李连城; 曲延英

    2014-01-01

    【目的】鉴定大豆抗逆相关转录因子 GmDREB5的互作蛋白,分析其互作蛋白 GmUBC13的特性及其生物学功能,解析GmDREB5提高植物抗逆性的分子机制。【方法】通过酵母双杂交系统,以大豆GmDREB5的AP2功能域为诱饵对干旱处理的大豆cDNA文库进行筛选,获得GmDREB5候选互作蛋白后通过酵母互作及体外Pull-down试验确定GmDREB5与候选蛋白之间的互作关系;同时,分析互作蛋白GmUBC13的进化关系、蛋白结构及亚细胞定位等特性;通过半定量RT-PCR分析其互作蛋白GmUBC13在干旱、高盐、低温等非生物胁迫和激素ABA处理下的表达谱;通过转化烟草鉴定GmUBC13的生物学功能。【结果】通过筛选大豆干旱处理的cDNA文库获得一个GmDREB5互作蛋白GmUBC13(ubiquitin conjugating enzyme 13),GmUBC13属于泛素结合酶蛋白家族,GmUBC13含有UBCc保守域(ubiquitin-conjugating enzyme catalytic domain)、与泛素连接酶E3互作的氨基酸残基以及高度保守的半胱氨酸催化位点。进化树分析表明,GmUBC13的氨基酸序列与拟南芥(Arabidopsisthaliana)含有16个成员的E2家族的第XV亚组的AtUBC13A、AtUBC13B以及水稻(Oryza sativa)的泛素结合酶蛋白Os01g0673600分别具有99%、97%和97%的同源性。酵母互作试验及体外Pull-down分析证明GmUBC13与GmDREB5蛋白之间存在相互作用。表达特性分析表明,GmUBC13受干旱、高盐、低温等非生物胁迫和激素ABA处理的诱导表达。GmUBC13在ABA的胁迫条件下,1 h开始有表达,10 h时表达量上升到最大,24 h稍微降低;在干旱和盐胁迫条件下,1 h开始表达,并随着胁迫时间的增长,表达量逐渐上升,24 h表达量达到最大;在低温胁迫条件下,GmUBC13受诱导较快,5 h表达达到最大,在10 h和24 h时未表达。蛋白亚细胞定位结果显示,GmDREB5蛋白定位在细胞核和细胞膜上,GmUBC13定位在细胞

  13. Doña Mencía de Mendoza y su residencia en el Palacio del Real en Valencia

    Directory of Open Access Journals (Sweden)

    Hidalgo Ogáyar, Juana

    2011-03-01

    Full Text Available Documents preserved in the Archivo del Palau reveal the furnishings that Mencía de Mendoza had in the Royal Palace at Valencia, particularly luxury beds such as those of the Empress Isabel of Portugal and Queen Mary of France. Painters active at her court, especially Juan de Bolaños, are also discussed.

    Con la ayuda de varios documentos conservados en el Archivo del Palau, se dan a conocer diferentes enseres que Doña Mencía de Mendoza tenía en el Palacio del Real en Valencia, destacando camas de lujo como la de la Emperatriz Isabel de Portugal o la de María de Francia. Se dan a conocer algunos pintores activos en su corte como Juan de Bolaños.

  14. Forecasting the Feasibility of Implementing Isolation Perimeters Between GM and non-GM Maize Fields Under Agricultural Conditions

    Science.gov (United States)

    Devos, Yann; Cougnon, Mathias; Thas, Olivier; De Clercq, Eva M.; Cordemans, Karl; Reheul, Dirk

    2008-10-01

    Although spatially isolating genetically modified (GM) maize fields from non-GM maize fields is a robust on-farm strategy to keep the adventitious presence of GM material in the harvests of neighboring non-GM maize fields due to cross-fertilizations below established labeling thresholds (and thus to ensure the spatial co-existence between maize cropping systems), the practical implementation of isolation perimeters attracted little research efforts. In this study, the feasibility of implementing isolation perimeters around GM maize fields is investigated. Using Geographic Information System datasets and Monte Carlo simulations, various scenarios differing in shares and spatial distributions of GM maize were tested for various isolation perimeters in six agricultural areas in Flanders. Factors that affect the feasibility of implementing isolation perimeters are discussed.

  15. TALE nucleases and next generation GM crops.

    KAUST Repository

    Mahfouz, Magdy M.

    2011-04-01

    Site-specific and adaptable DNA binding domains are essential modules to develop genome engineering technologies for crop improvement. Transcription activator-like effectors (TALEs) proteins are used to provide a highly specific and adaptable DNA binding modules. TALE chimeric nucleases (TALENs) were used to generate site-specific double strand breaks (DSBs) in vitro and in yeast, Caenorhabditis elegans, mammalian and plant cells. The genomic DSBs can be generated at predefined and user-selected loci and repaired by either the non-homologous end joining (NHEJ) or homology dependent repair (HDR). Thus, TALENs can be used to achieve site-specific gene addition, stacking, deletion or inactivation. TALE-based genome engineering tools should be powerful to develop new agricultural biotechnology approaches for crop improvement. Here, we discuss the recent research and the potential applications of TALENs to accelerate the generation of genomic variants through targeted mutagenesis and to produce a non-transgenic GM crops with the desired phenotype.

  16. TALE nucleases and next generation GM crops.

    Science.gov (United States)

    Mahfouz, Magdy M; Li, Lixin

    2011-01-01

    Site-specific and adaptable DNA binding domains are essential modules to develop genome engineering technologies for crop improvement. Transcription activator-like effectors (TALEs) proteins are used to provide a highly specific and adaptable DNA binding modules. TALE chimeric nucleases (TALENs) were used to generate site-specific double strand breaks (DSBs) in vitro and in yeast, Caenorhabditis elegans, mammalian and plant cells. The genomic DSBs can be generated at predefined and user-selected loci and repaired by either the non-homologous end joining (NHEJ) or homology dependent repair (HDR). Thus, TALENs can be used to achieve site-specific gene addition, stacking, deletion or inactivation. TALE-based genome engineering tools should be powerful to develop new agricultural biotechnology approaches for crop improvement. Here, we discuss the recent research and the potential applications of TALENs to accelerate the generation of genomic variants through targeted mutagenesis and to produce a non-transgenic GM crops with the desired phenotype.

  17. An intervention analysis on the relationship between futures prices of non-GM and GM contract soybeans in China

    OpenAIRE

    2015-01-01

    China adopted a mandatory labeling policy of Genetically Modified (GM) food products in 2002. The strategy of separating trading was intended by Chinese regulators to protect domestic non-GMO production, provide non-GM soybean growers a higher selling price, and facilitate marketing. On December 22, 2004, the Dalian Commodity Exchange (DCE) introduced a separate futures contract for No. 2 soybeans, which includes GM soybeans. With this change, the No. 1 soybean futures contract defaulted to a...

  18. Centralización de la represión, violencia paraestatal y redes internacionales represivas en la Mendoza predictatorial

    Directory of Open Access Journals (Sweden)

    Laura Rodriguez Aguero

    2014-04-01

    Full Text Available Durante el tercer gobierno peronista (1973-1976 comenzó a montarse el dispositivo represivo que marcó los prolegómenos del Terrorismo de Estado llevado adelante por la dictadura militar de 1976. En Mendoza, la violencia paraestatal fue llevada a cabo por el CAM (Comando Anticomunista Mendoza, y el Comando Moralizador Pío XII. En este trabajo nos proponemos realizar a partir del uso de fuentes escritas y del testimonio de algunos/as sobrevivientes, una reconstrucción del accionar paraestatal, en vistas a analizar, por un lado, cómo se constituyeron en la dinámica local, las redes de relaciones implicadas en la práctica represiva y la inflexión que implicó noviembre de 1975 en la centralización de la represión; y por otro lado, cómo se manifestó el carácter internacional de la represión y la idea de aniquilación del “enemigo interno” en Mendoza, partiendo de la hipótesis de que la misma adquirió proporciones inusitadas debido a su carácter de provincia de frontera y su cercanía con Chile, en un momento de articulación de redes represivas en el Cono Sur.

  19. The future of starch bioengineering:GM microorganisms or GM plants?

    OpenAIRE

    Kim Henrik eHebelstrup; Domenico eSagnelli; Andreas eBlennow

    2015-01-01

    Plant starches regularly require extensive modification to permit subsequent applications. Such processing is usually done by the use of chemical and/or physical treatments. The use of recombinant enzymes produced by large-scale fermentation of GM microorganisms is increasingly used in starch processing and modification, sometimes as an alternative to chemical or physical treatments. However, as a means to impart the modifications as early as possible in the starch production chain, similar r...

  20. MARKETING MECHANISMS TO FACILITATE CO-EXISTENCE OF GM AND NON-GM CROPS

    OpenAIRE

    Henry, Benjamin; William W. WILSON; Dahl, Bruce L.

    2006-01-01

    Development of genetically modified (GM) and specialty crops has had a great impact on the grain handling industry during recent years. Added costs associated with handling these crops have become an important issue for grain handlers. For this study, data were collected from a survey of elevators in the Upper Midwest. The information focused on segregation practices, time requirements, and costs. This study shows the different costs (grading and handling) associated with segregation practice...

  1. Exploitation of molecular profiling techniques for GM food safety assessment

    NARCIS (Netherlands)

    Kuiper, H.A.; Kok, E.J.; Engel, K.H.

    2003-01-01

    Several strategies have been developed to identify unintended alterations in the composition of genetically modified (GM) food crops that may occur as a result of the genetic modification process. These include comparative chemical analysis of single compounds in GM food crops and their conventional

  2. Examining consumer behavior toward genetically modified (GM) food in Britain.

    Science.gov (United States)

    Spence, Alexa; Townsend, Ellen

    2006-06-01

    This study examined behavior toward genetically modified (GM) food in a British community-based sample. We used an equivalent gain task in which participants actually received the options they chose to encourage truthful responding. In conjunction with this, theory of planned behavior (TPB) components were evaluated so as to examine the relative importance of behavioral influences in this domain. Here, the TPB was extended to include additional components to measure self-identity, moral norms, and emotional involvement. Results indicated that the monetary amounts participants accepted in preference to GM food were significantly lower than those accepted in preference to non-GM food. However, the vast majority of participants were indifferent between GM and non-GM food options. All TPB components significantly predicted behavioral intentions to try GM food, with attitudes toward GM being the strongest predictor. Self-identity and emotional involvement were also found to be significant predictors of behavioral intentions but moral norms were not. In addition, behavioral intentions significantly predicted behavior; however, PBC did not. An additional measure of participants' propensity to respond in a socially desirable manner indicated that our results were not influenced by self-presentation issues, giving confidence to our findings. Overall, it appears that the majority of participants (74.5%) would purchase GM food at some price.

  3. Integrating insect-resistant GM Crops in pest management systems

    Science.gov (United States)

    In 2006, GM cotton and maize with insect resistance were grown on 12.1 and 20.1 million hectares in 9 and 13 countries, respectively. These insect resistant GM crops produce various Cry toxins from Bacillus thuringiensis (Bt) and provide highly selective and effective control of lepidopteran and col...

  4. Environmental and agronomic impact of the herbicide tolerant GM rapeseed

    Directory of Open Access Journals (Sweden)

    Zdjelar Gordana R.

    2011-01-01

    Full Text Available The introduction of genetically modified herbicide tolerant rapeseed has raised questions concerning the possible transfer of transgenes into wild relatives or neighbouring fields with similar crops. Pollen of rapeseed can be spread in the area and if a non-GM crop is fertilised by GM pollen, some percentage of the collected seed product will contain GM. Current regulation in the EU limits the allowed content. For conventional crops the critical level of GM contamination is in practice below 0.9%, which is the threshold value for labelling of GM in food and feed by the EU, although the limit for seeds is 0.1% in Serbia. In organic farming, the regulations do not allow the use of genetic engineering in the grain production system.

  5. Consumers’ perceptions on GM food safety in urban China

    Institute of Scientific and Technical Information of China (English)

    HUANG Ji-kun; PENG Bo-wen

    2015-01-01

    The debate about the safety of geneticaly modiifed (GM) food has attracted public attention in concurrence with the rapid development of agricultural biotechnology. This paper examines the consumers’ perceptions on the safety of GM food in China. Based on a unique survey dataset, this study shows that consumers in urban China have signiifcantly changed their perceptions on GM food safety. The percentage of consumers who perceived such food as unsafe for consumption increased by more than 30% in the 2002–2012 period. Approximately half of the consumers did not have an opinion on this issue. Major shifts have been occurred after 2010, likely because of the increasing inlfuence of negative media reports on GM technology in recent years. Several individual and household’s characteristics are shown to signiifcantly affect consumers’ perceptions on GM food safety, such as gender, education, food alergy experience and resident city size. The paper concludes with policy implications.

  6. Media attention to GM food cases: An innovation perspective.

    Science.gov (United States)

    Flipse, Steven M; Osseweijer, Patricia

    2013-02-01

    Media attention to genetically modified (GM) foods has been described as negative, especially in Europe. At the turn of the century appreciation of GM foods was at an all-time low in Europe. Food manufacturers are still careful in the use, development and communication of GM based food products, and their caution influences innovation processes. In this study we explore the link between media attention and innovation practice. Media attention to three specific high-profile GM food cases is described and linked to innovation practice. We elucidate the order of events in these cases and show that publics could only to a limited extent have formed an opinion on GM based food products based on scientifically valid data through written English media. Innovators in food biotechnology may benefit from this knowledge for future product development and marketing, and we suggest that innovation may benefit from early stakeholder involvement and communication activities.

  7. La lacertofauna de Mendoza: lista actualizada, distribución y riqueza

    Directory of Open Access Journals (Sweden)

    Corbalán, Valeria

    2008-04-01

    Full Text Available La provincia de Mendoza posee una rica fauna de lagartos pertenecientes a las familias Leiosauridae, Liolaemidae, Teiidae, Scincidae y Gekkonidae. Algunos son propios del Monte, Puna, Payunia o región andina, mientras que otros poseen una amplia distribución, ocupando dos o más ecosistemas. El objetivo de este trabajo fue actualizar la lista lacertofaunística de la provincia y determinar las áreas de mayor riqueza de especies en relación a estos cuatro tipos de ecosistemas. Se utilizaron datos de procedencia de 43 especies de lagartos a partir de colecciones herpetológicas y de bibliografía. Las localidades fueron georreferenciadas y mapeadas. Una primera estimación de las áreas de mayor riqueza fue realizada sobre la base de las distribuciones de acuerdo a los puntos de colecta. En un segundo análisis, se generaron modelos predictivos de distribución utilizan-do 26 variables ambientales. Estas áreas potenciales fueron superpuestas a fin de obtener el número de especies en cuadrículas de 4,6 km x 4,6 km. Los resultados de ambos métodos indican que la mayor riqueza de especies se encuentra en la Payunia, probablemente en relación a la mayor heterogeneidad ambiental de la zona, ya que es considerada un área ecotonal entre la región fitogeográfica de la Patagonia y el Monte. Un análisis de similitud (Índice de Morisita demuestra que la similitud entre ecosistemas en cuanto a la composición de especies es baja, conformándose dos grupos: el Monte y Patagonia por un lado, y el ecosistema Andino y Puneño por otro. Mendoza province has a rich fauna of lizards that belongs to the Leiosauridae, Liolaemidae, Teiidae, Scincidae and Gekkonidae families. Some of them are typical of the Monte, Puna, Payunia or Andean region, whereas some others are widespread, inhabiting two or more ecosystems. The objective of this work is to perform an updating of the Mendoza lizard fauna and to determine the most highly species-rich areas related to

  8. Mercado de trabajo y condiciones de vida en Mendoza a comienzos del siglo XX

    Directory of Open Access Journals (Sweden)

    Juan Manuel Cerdá

    2006-01-01

    Full Text Available El propósito del presente trabajo es analizar los cambios y las continuidades en el proceso de formación del mercado de trabajo en la provincia de Mendoza a comienzos del siglo XX. La incorporación de un número significativo de inmigrantes a finales del siglo XIX junto a un proceso de reorganización productiva asociado al desarrollo de la industria vitivinícola, implicó cambios en las relaciones sociales y en las condiciones de vida de amplios sectores de la población mendocina. Iniciado el siglo XX, la vitivinicultura se convirtió en la principal actividad productiva de la provincia y la más importante en su rubro a nivel nacional. Los viñateros, productores agroindustriales, industriales bodegueros, contratistas de viñas , etc., fueron constituyéndose en parte de una sociedad cada vez más heterogénea y diversa, producto del desarrollo capitalista que experimentó la región desde el último tercio del siglo XIX y que se insertó en el proceso de incorporación de la economía Argentina al mercado mundial. Este período resulta de suma importancia porque se determinó un sistema productivo en torno a la actividad vitivinícola de la provincia que dio forma al mercado de trabajo regional. En este contexto, la inserción de los trabajadores se dio de una manera muy dispar en el proceso productivo, caracterizado por una alta estacionalidad y una escasa especialización de la mano de obra requerida.The aim of this work is to analyze the changes and continuities during the process of formation of the labor market in the province of Mendoza in the early 1900s. Wide sectors of the Mendoza population saw their life conditions and social interactions change as a result of the absorption of a significant amount of immigrants by the end of 19 th century, together with a restructuring of production connected to the development of the wine industry. Shortly after the turn of the century, wine had become the main productive activity of that

  9. Consecutive Bright Pulses in the Vela Pulsar

    CERN Document Server

    Palfreyman, Jim L; Dickey, John M; Young, Timothy G; Hotan, Claire E; 10.1088/2041-8205/735/1/L17

    2011-01-01

    We report on the discovery of consecutive bright radio pulses from the Vela pulsar, a new phenomenon that may lead to a greater understanding of the pulsar emission mechanism. This results from a total of 345 hr worth of observations of the Vela pulsar using the University of Tasmania's 26 m radio telescope to study the frequency and statistics of abnormally bright pulses and sub-pulses. The bright pulses show a tendency to appear consecutively. The observations found two groups of six consecutive bright pulses and many groups of two to five bright pulses in a row. The strong radio emission process that produces the six bright pulses lasts between 0.4 and 0.6 s. The numbers of bright pulses in sequence far exceed what would be expected if individual bright pulses were independent random events. Consecutive bright pulses must be generated by an emission process that is long lived relative to the rotation period of the neutron star.

  10. Desarrollo poblacional de Diaspidiotus perniciosus (Hemiptera: Diaspididae en cultivos de manzano de San Carlos, Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Guillermo P. LOPEZ GARCIA

    2011-01-01

    Full Text Available Se estudió la bionomía de Diaspidiotus perniciosus Comstock (“escama de San José”, en manzanos de la variedad “Red delicious” de San Carlos, Mendoza, Argentina, durante los ciclos productivos 2007-2008 y 2008-2009. Se determinó el número de generaciones anuales y se estudiaron las fluctuaciones poblacionales asociadas a la integral térmica para la especie en esta región. D. perniciosus presenta dos generaciones superpuestas al ciclo del cultivo, mientras que las ninfas (N1 y N2 de la tercera generación se desarrollan solamente hasta el final de la temporada estival y pasan al estado de quiescencia, en el que permanecen durante el invierno. El desarrollo de D. perniciosus en esta zona coincide con el de esta especie en la zona frutícola del centro de Chile en cuanto al número de generaciones y al periodo de quiescencia invernal. La población quiescente en Chile está integrada predominantemente por ninfas del primer estadio (N1, mientras que en San Carlos, Mendoza, la población quiescente está integrada principalmente por ninfas del segundo estadio (N2. La similitudes entre ambas poblaciones se deben, probablemente, a las coincidencias en latitud, clima y especie hospedera. El impacto económico de D. perniciosus en la zona de estudio tiene mayor relevancia durante los meses de diciembre y enero, cuando se observa una alta incidencia de daños en los frutos y las hojas; este es el momento decisivo para implementar medidas de control fitosanitario. Estas deberán aplicarse en función de los máximos poblacionales de N1 que se producen con 600-650 Grados-Día (oD en diciembre y con 1.170-1.270oD en enero. En las temporadas en las que la densidad poblacional de la plaga es especialmente alta, podrían incorporarse medidas adicionales de control con 1.800-2.000oD durante el mes de abril. Los resultados de estos estudios representan una herramienta predictiva, que permitirá elaborar estrategias para el control de poblaciones de

  11. Brightness-equalized quantum dots

    Science.gov (United States)

    Lim, Sung Jun; Zahid, Mohammad U.; Le, Phuong; Ma, Liang; Entenberg, David; Harney, Allison S.; Condeelis, John; Smith, Andrew M.

    2015-10-01

    As molecular labels for cells and tissues, fluorescent probes have shaped our understanding of biological structures and processes. However, their capacity for quantitative analysis is limited because photon emission rates from multicolour fluorophores are dissimilar, unstable and often unpredictable, which obscures correlations between measured fluorescence and molecular concentration. Here we introduce a new class of light-emitting quantum dots with tunable and equalized fluorescence brightness across a broad range of colours. The key feature is independent tunability of emission wavelength, extinction coefficient and quantum yield through distinct structural domains in the nanocrystal. Precise tuning eliminates a 100-fold red-to-green brightness mismatch of size-tuned quantum dots at the ensemble and single-particle levels, which substantially improves quantitative imaging accuracy in biological tissue. We anticipate that these materials engineering principles will vastly expand the optical engineering landscape of fluorescent probes, facilitate quantitative multicolour imaging in living tissue and improve colour tuning in light-emitting devices.

  12. Longitudinal Taphonomic Studies of Mammal Carcasses from the Rio Salado Valley, Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Clara Otaola

    2016-02-01

    Full Text Available Taphonomic studies aid in understanding the transition of organic matter from living contexts (the biosphere to geological contexts (the lithosphere, and how agents and processes affect skeletal remains in the archaeological record. Archaeological research in the Atuel River valley, Mendoza, Argentina, has been carried out for several years. However, actualistic approaches to examine local and regional taphonomic processes have only been recently developed in this area. Longitudinal studies of disarticulation and dispersion of bones from carcasses are presented here in order to understand how skeletal materials are naturally added to, subtracted from, and mixed within the archaeological record. In this paper we explore variability in the influence of taphonomic processes in different microhabitats of the valley and how these mechanisms impact the potential of mixing during bone deposition in the archaeological record. There are some qualitative differences between carcasses deposited in different landforms, showing that each place has its own taphonomic history, principally influenced by the geomorphic and ecologic processes that operate in different landforms.

  13. Payenia Quaternary flood basalts (southern Mendoza, Argentina: Geophysical constraints on their volume

    Directory of Open Access Journals (Sweden)

    Mauro G. Spagnuolo

    2016-09-01

    Full Text Available The Quaternary volcanic province of Payenia is located in southern Mendoza and northern Neuquén provinces of Argentina and is characterized by a dominant basaltic composition. The volcanic province covers an area larger than 40,000 km2 and its origin and evolution has been the center of several studies. In this study we analyzed gravity data together with more accurate volcanic volumes calculations in order to investigate the subsurface structure of the Payenia volcanic province. The volume of material was calculated using digital elevation models and geographic information system (GIS techniques to estimate the volume of material erupted and then, with those values, make an estimation of the intrusive material that could be located within the crust. The results of the calculations were compared with different 2D-sections constructed to model the gravity data and compare with the observed satellite gravity. After evaluating different models which have been generated to match both: the observed gravity data and the subsurface material calculated, we discuss those that best fit with observation. The results clearly indicate that the lithosphere is attenuated below the region.

  14. Payenia Quaternary flood basalts (southern Mendoza, Argentina):Geophysical constraints on their volume

    Institute of Scientific and Technical Information of China (English)

    Mauro G. Spagnuolo; Darío L. Orts; Mario Gimenez; Andres Folguera; Victor A. Ramos

    2016-01-01

    The Quaternary volcanic province of Payenia is located in southern Mendoza and northern Neuquén provinces of Argentina and is characterized by a dominant basaltic composition. The volcanic province covers an area larger than 40,000 km2 and its origin and evolution has been the center of several studies. In this study we analyzed gravity data together with more accurate volcanic volumes calculations in order to investigate the subsurface structure of the Payenia volcanic province. The volume of material was calculated using digital elevation models and geographic information system (GIS) techniques to estimate the volume of material erupted and then, with those values, make an estimation of the intrusive material that could be located within the crust. The results of the calculations were compared with different 2D-sections constructed to model the gravity data and compare with the observed satellite gravity. After evaluating different models which have been generated to match both: the observed gravity data and the subsurface material calculated, we discuss those that best fit with observation. The results clearly indicate that the lithosphere is attenuated below the region.

  15. Paleomagnetism of Upper Triassic rocks in the Los Colorados hill section, Mendoza province, Argentina

    Science.gov (United States)

    Vizán, Haroldo; Ixer, Robert; Turner, Peter; Cortés, José María; Cladera, Gerardo

    2004-12-01

    Different authors have highlighted a systematic disagreement between Late Carboniferous-Triassic paleomagnetic poles (PPs) for Gondwanaland and Laurasia when they are repositioned in a classical reconstruction prior to the breakup of Pangea A. This disagreement has been interpreted in geodynamic terms or as an evidence of non-dipole components of the geomagnetic field. Such analyses have been made using data on South American PPs published approximately 25 years ago and obtained using outdated methodologies. In this article, the authors present new Late Triassic paleomagnetic data from rocks that crop out in the Pre-Andean ranges (Precordillera) of Mendoza province (Argentina). Samples of different lithologies were taken from two limbs of a doubly plunging syncline, and several field tests of paleomagnetic stability were applied. The results indicate primary site mean directions that yield a PP with geographic coordinates and statistical parameters as follows: Lat.=76°S, Lon.=280°E, N=12, R=11.63, α95=8°, K=30.2. This PP agrees with mean PPs of Laurasia of similar ages in different models of Pangea A, indicating that the hypothesis of a dipolar paleomagnetic field could be valid for the Late Triassic.

  16. Diseño participativo de espacios urbanos bioclimáticos. Experiencia en Mendoza (Argentina

    Directory of Open Access Journals (Sweden)

    Claudia Fernanda Martinez

    2015-04-01

    Full Text Available El presente trabajo reconoce los beneficios de las técnicas participativas de diseño para la producción social y sustentable del hábitat, al equilibrar soluciones bioclimáticas con los intereses de los beneficiarios. Como metodología, se aplicaron talleres comunitarios orientados tradicionalmente solo a la vivienda, para el diseño participativo de espacios urbanos conexos y sus redes en un conjunto habitacional de la provincia de Mendoza (Argentina. El desarrollo de talleres de diseño participativo pone de manifiesto la importancia de transferir a la comunidad beneficiaria de planes de vivienda de interés social los conceptos de la arquitectura bioclimática y sus implicaciones en la calidad de vida de las personas, el ahorro energético y la sustentabilidad ambiental. Los resultados indican que es posible conciliar el diseño de espacios urbanos eficientes energética y ambientalmente con cero sobrecosto y que, al mismo tiempo satisfagan las expectativas de los usuarios.

  17. Flood risk assessment. Case of study: Motozintla de Mendoza, Chiapas, Mexico

    Directory of Open Access Journals (Sweden)

    David A. Novelo-Casanova

    2016-09-01

    Full Text Available Due to its geographical location, the community of Motozintla de Mendoza (Motozintla in the State of Chiapas, Mexico, is continuously exposed to the impact of natural hazards. In this work, we assessed the flood risk of Motozintla considering the structural, socioeconomic, organizational, and global (structural, socioeconomic, and organizational vulnerabilities. In addition, we also measured the local risk perception. Spatial maps were generated to determine the most vulnerable and risk areas of this community. Our results indicate that the population has a high level of risk to flooding mainly because (1 the majority of the local houses has high structural vulnerability; (2 a high percentage of the families has a daily income less than the official Mexican minimum wage and lacks of basic public services as well as of proper social security services; (3 most of the community does not know any existing Civil Protection Plan; and (4 the community organization for disaster mitigation and response is practically non-existent. For these reasons, we believe that it is necessary for local authorities to establish in the short-term, preparedness, mitigation and response plans as well as land-use measures to reduce the risk to floods in Motozintla.

  18. Les variations glaciaires dans les Andes de Mendoza (Argentine entre 1975 et 2007

    Directory of Open Access Journals (Sweden)

    Étienne Cossart

    2010-05-01

    Full Text Available Le suivi des glaciers constitue un enjeu essentiel pour l’organisation des sociétés et le fonctionnement des milieux montagnards. Dans la mesure où les glaciers influencent fortement le régime des cours d’eau, et donc les stratégies d’irrigation, leur disparition peut remettre en cause de nombreux usages liés à l’eau. Or, si nombre de glaciers sont étudiés individuellement, des méthodes permettant d’effectuer des suivis de l’englacement à l’échelle régionale manquent. Nous proposons donc ici une méthode, fondée sur la reconstitution de champs d’altitudes de la Ligne d’Équilibre Glaciaire, aboutissant à la réalisation de cartes diachroniques régionales. Nous synthétisons ainsi les variations glaciaires depuis 30 ans sur l’ensemble d’un secteur de plusieurs milliers de kilomètres carr��s : les Andes de Mendoza (Argentine.

  19. Hilos de agua, lazos de sangre: enfrentando la escasez en el desierto de Lavalle (Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    L.M. Torres

    2008-01-01

    Full Text Available En el trabajo se analizan las posibles relaciones existentes entre las dinámicas de uso de los recursos naturales y las estrategias de localización de las unidades domésticas en el territorio, dentro de espacios rurales de desierto que poseen una oferta ambiental limitada. ¿Cómo, en el marco de qué estrategias, los grupos humanos convierten distintas porciones de la naturaleza en recurso natural? y ¿cómo usan y administran esos recursos en procura de asegurar su propia reproducción social? Para avanzar en esta dirección se analiza un estudio de caso (el desierto de Lavalle, provincia de Mendoza, Argentina y, dentro de él, se procede con las técnicas cualitativas de entrevista en profundidad y observación participante. Los datos que se presentan sugieren que en los territorios analizados rurales, emplazados en tierras secas, afectados por desertificación y con elevados índices de pobreza- las limitaciones que impone el medio ambiente son sobrellevadas –en alguna medida- mediante una estrategia de localización íntimamente relacionada con el proceso de producción, que maximiza el acceso de determinados recursos naturales y que "ordena" la competencia por ellos con los vecinos y parientes.

  20. Peritidal cyclic sedimentation from La Manga Formation (Oxfordian), Neuquén Basin, Mendoza, Argentina

    Science.gov (United States)

    Palma, Ricardo M.; Kietzmann, Diego A.; Bressan, Graciela S.; Martín-Chivelet, Javier; López-Gómez, José; Farias, María E.; Iglesias Llanos, María P.

    2013-11-01

    The La Manga Formation consists of marine carbonates and represents most of the sedimentary record of the Callovian-Oxfordian in the Neuquén Basin. Three localities in the southern Mendoza province were studied and their cyclicity was determined by means of facies analysis and their vertical arrangement. Facies of inner ramp, that were deposited in extremely shallow-water environments with intermittent subaerial exposures have been broken down into shallow subtidal, and intertidal-supratidal environments. Shallow subtidal facies are arranged into decimetre scale upward-shallowing cycles composed of marls, laminated or massive mudstones or bioclastic wackestones and intraclastic wackestone-packstones. Intertidal-supratidal centimetre-scale cycles consist of an upward-shallowing succession of restricted facies, overlaid by horizontal or crinkle microbial laminites, flat pebble conglomerates or breccias beds. The defined cycles show a shallowing upward trend in which the evidence of relative sea-level lowering is accepted. The interpretation of Fischer plots allowed the recognition of changes in accommodation space.

  1. Seismic reflection survey at Llancanelo region (Mendoza, Argentina) and preliminary interpretation of Neogene stratigraphic features

    Science.gov (United States)

    Osella, A.; Onnis, L.; de la Vega, M.; Tassone, A.; Violante, R. A.; Lippai, H.; López, E.; Rovere, E. I.

    2015-07-01

    A shallow multichannel seismic survey reaching depths of 700/800 m was performed for the first time in the Llancanelo Lake region (Southern Mendoza Province, Argentina), in order to depict the major Neogene sedimentary-volcanic sequences that form the final infilling of the tectonic-volcanic basin where the lake is located. The seismic survey advances on the results of previous geoelectric and electromagnetic surveys carried out at early stages of the research that reached the uppermost 80-100 m of the sequences (Quaternary), and therefore they go deeper in the subsoil. All the surveys were supported by surface and subsoil geological observations. After explaining the details of the performed seismic methodology, the obtained results are discussed, which indicate the presence of three major sedimentary units with increasing volcanic (basaltic layers) intercalations with depth, that accommodate to the geometry of the depocenter. The entire sequence encompasses most of the Neogene. This research sets the methodological basis for future, more detailed shallow seismic surveys in the region.

  2. Darwin's observation in South America: what did he find at agua de la zorra, Mendoza province?

    Directory of Open Access Journals (Sweden)

    Stella Poma

    2009-04-01

    Full Text Available Scarcely 23 km from Uspallata, along the track of the old national highway 7, lies the district of Agua de la Zorra, in Mendoza province in western Argentina. Charles Darwin visited the area during his South American journeys in the 19th century and discovered a geological sequence that contained a paleoflora never described before. The flora includes an important number of species, particularly what is considered a small conifer forest with many silicified trunks still in life position. Darwin described and interpreted the sequence as sedimentary; his records show a very detailed level of observation. He also wondered about the processes that would cause the burial of the paleoflora, which he considered had happened in a marine sedimentary environment. In the modern geological framework and after a detailed study of the rocks containing the trunks, it is now interpreted that the conifer forest was buried by pyroclastic flows. Darwin accurately described the fine volcanic materials as an essential part of the deposit, but the key of the enigma about the origin of the deposits and the burial of the forest is the identification of the pyroclastic flow features; these were unknown process at the time of Darwin´s observations and interpretation.

  3. Projectile motion in Diego Hurtado de Mendoza's Mecánica and new Renaissance dynamics

    Directory of Open Access Journals (Sweden)

    Iommi Echeverría, Virginia

    2011-06-01

    Full Text Available This article considers Diego Hurtado de Mendoza’s translation of the Aristotelian Mechanics in relation to the humanistic and scientific Italian environment of the Renaissance. From the analysis of the last problems on dynamics, it demonstrates the affinity with the works of Piccolomini and Cardano. It also shows the originality of the exegesis made by the Spanish author of Problem XXXIV, in which he combines latemedieval physics with the Aristotelian explanation.Este artículo examina la traducción hecha por Diego Hurtado de Mendoza de la Mecánica aristotélica en el contexto del ambiente científico-humanista italiano de mediados del siglo XVI. A partir del análisis de los últimos problemas sobre dinámica, se demuestra su estrecha relación con las obras de Piccolomini y Cardano; sugiriéndose además la originalidad de la interpretación hecha por el autor español del problema XXXIV basada en la combinación de la física tardomedieval y la explicación aristotélica.

  4. El arriero y el transporte terrestre en el Cono Sur (Mendoza, 1780-1800

    Directory of Open Access Journals (Sweden)

    Lacoste, Pablo

    2008-12-01

    Full Text Available This paper explores the muleteer as an economic actor in terrestrial transportation in South Cone, specially in the route across the Andes in order to connect Atlantic and Pacific markets. Since Mendoza’s customs records, this study has processed 120.000 freight-carrying mules to know the origin and destiny places, main routes, volume and kind of charge. The muleteer promoted an intensive activity in terms of transportation, trade and wine industry. As a result, he leaded the rise of a regional proto-bourgeoisie.

    El artículo examina al arriero como actor económico en el transporte terrestre del Cono Sur, sobre todo en la ruta a través de la Cordillera de los Andes, para enlazar los mercados del Atlántico y el Pacífico. A partir de los manuales de Cargo y Data de la Aduana de Mendoza, se han procesado 120.000 mulas de carga para determinar los lugares de origen y destino, principales rutas, volumen y tipo de carga transportada. El arriero impulsó una intensa actividad en el transporte, el comercio y en la industria vitivinícola; como resultado, este actor promovió el surgimiento de una protoburguesía regional.

  5. Osteoporosis Self-Assessment Tool Performance in a Large Sample of Postmenopausal Women of Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Fernando D. Saraví

    2013-01-01

    Full Text Available The Osteoporosis Self-assessment Tool (OST is a clinical instrument designed to select patients at risk of osteoporosis, who would benefit from a bone mineral density measurement. The OST only takes into account the age and weight of the subject. It was developed for Asian women and later validated for European and North American white women. The performance of the OST in a sample of 4343 women from Greater Mendoza, a large metropolitan area of Argentina, was assessed. Dual X-ray absorptiometry (DXA scans of lumbar spine and hip were obtained. Patients were classified as either osteoporotic (N=1830 or nonosteoporotic (n=2513 according to their lowest T-score at any site. Osteoporotic patients had lower OST scores (P<0.0001. A receiver operating characteristic (ROC curve showed an area under the curve of 71% (P<0.0001, with a sensitivity of 83.7% and a specificity of 44% for a cut-off value of 2. Positive predictive value was 52% and negative predictive value was 79%. The odds ratio for the diagnosis of osteoporosis was 4.06 (CI95 3.51 to 4.71; P<0.0001. It is concluded that the OST is useful for selecting postmenopausal women for DXA testing in the studied population.

  6. Pollution trends using bark of morus alba in the cities of buenos aires and mendoza (Argentina Tendências de poluição usando cascas de morus alba nas cidades de buenos aires e mendoza (Argentina

    Directory of Open Access Journals (Sweden)

    Patricia Perelman

    2010-06-01

    Full Text Available A comparative study of elements deposited on tree bark was carried out for urban and periurban areas of two of the most important cities in Argentina. The content of Fe, Mg, Al, Mn, Zn, Pb, Ba, Cr, Hg, Cu, Ni, Cd and Sb was determined by inductively coupled plasma atomic emission spectrometry (ICP-OES in Morus alba tree bark collected in the cities of Buenos Aires and Mendoza. The main air pollutants detected in the Buenos Aires urban area were Ba, Cr, Cu and Ni and indicate significative difference from the Mendoza urban and periurban areas. Significantly, higher concentrations of Zn, Ba, Cr and Cu were recorded in the periurban area of the city of Buenos Aires than in Mendoza. Bark samples were strongly influenced by dust and show Al, Fe, Mg and other element accumulations that indicate that soil particles were carried out by wind. Elements like Ba and Zn, commonly linked to traffic emissions, showed the highest concentrations in the Buenos Aires metropolitan area, possibly due to more intensive vehicular traffic. Our results indicated that intensity of vehicular traffic and not city structure is responsible for air pollution.Um estudo comparativo dos elementos depositados nas cascas das árvores foi realizado nas áreas urbanas e na periferia de duas cidades das mais importantes da Argentina. Os índices do Fe, Mg, Al, Mn, Zn, Pb, Ba, Cr, Cu, Ni e do Sb foram determinados pela espectrometria da emissão atômica com plasma acoplado indutivamente (ICP-OES nas cascas da árvore Morus alba, coletados nas cidades de Buenos Aires e Mendoza. Os principais elementos da contaminação do ar detectadas na área urbana de Buenos Aires foram Ba, Cr, Cu e Ni, que indicaram diferenças significativas nas áreas urbanas e na periferia de Mendoza. Uma concentração do Zn, Ba, Cr e do Cu foi achada na periferia da cidade de Buenos Aires, significativamente mais elevada do que em Mendoza. As amostras da casca foram influenciadas fortemente pela poeira e

  7. Societal aspects of foods derived from GM crops

    DEFF Research Database (Denmark)

    Beekmann, V.; Frewer, L.F.; Lassen, J.

    2004-01-01

    from soy plants genetically modified to resist the herbicide Round-Up, represented the first large scale marketing of GM foods in Europe. Other applications of biotechnology soon followed: events, such as the attempted commercialisation of GM maize and other commodities, focused public attention......The first major controversy associated with gene technology in Europe took place in the late 1980s. At this time, there were no products actually being sold to consumers. In 1996, controversy over gene technology was triggered by the arrival of GM soybeans at European harbours. The soybeans, coming...

  8. High brightness semiconductor lasers with reduced filamentation

    DEFF Research Database (Denmark)

    McInerney, John; O'Brien, Peter.; Skovgaard, Peter M. W.;

    1999-01-01

    High brightness semiconductor lasers have applications in spectroscopy, fiber lasers, manufacturing and materials processing, medicine and free space communication or energy transfer. The main difficulty associated with high brightness is that, because of COD, high power requires a large aperture...

  9. Geología de la región del Cerro Guanaquero, Río Diamante, Mendoza Geology of Cerro Guanaquero region, Diamante River, Mendoza

    Directory of Open Access Journals (Sweden)

    Federico Fuentes

    2008-03-01

    Full Text Available El estudio realizado presenta nuevos datos sobre un sector poco conocido de la Cordillera Principal de Mendoza, en la alta cuenca del río Diamante en las adyacencias del cerro Guanaquero, y los primeros datos geocronológicos de sus rocas volcánicas. Las unidades geológicas presentes en el área se dividen en cuatro grupos principales: secuencias sedimentarias mesozoicas marinas y continentales intensamente plegadas y falladas; intrusivos y volcanitas intermedias de edad neógena; rocas volcánicas pliocenas a recientes de composición intermedia a básica, y depósitos cuaternarios inconsolidados. El cerro Guanaquero, un estratovolcán pliocuaternario intensamente erosionado por glaciares pleistocenos, con sus 4.841 metros es el rasgo orográfico más prominente. Está constituido esencialmente por andesitas grises porfíricas, piroxénicas a biotíticas. Intercaladas con las coladas andesíticas se presentan depósitos piroclásticos, aglomerados volcánicos, ignimbritas y basaltos. La datación de una andesita por el método K-Ar en roca total arrojó una edad de 1,4 ± 0,1 Ma. La deformación ándica comenzó en forma de una faja plegada y corrida de piel fina, con pliegues por despegue en el sector occidental y por propagación de falla en el oriental. La compresión al oeste de los 69º47´O terminó por invertir la fallas normales del rift mesozoico. A lo largo de este meridiano se encuentra la falla más importante de la región, la que se ha correlacionado con la falla Malargüe, bien desarrollada en latitudes más australes. Esta falla limita la faja plegada y corrida del Aconcagua, de naturaleza epidérmica, y la faja plegada y corrida de Malargüe, controlada por la inversión tectónica del basamento. El volcanismo fue muy intenso en el Plioceno y el Cuaternario, correspondiendo a un período de empinamiento de la placa oceánica subducida, en el que la región ha sido levantada pasivamente. La alta resistencia a la erosión de

  10. Evidencias de la zona de contacto entre los terrenos de Precordillera y Pie de Palo, Provincias de San Juan y Mendoza Evidence of the contact area between Precordillera and Pie de Palo terranes, Provinces of San Juan and Mendoza.

    OpenAIRE

    Maximiliano García Torrejón; Orlando Alvarez Pontoriero; Silvina Nacif; Iván Novara; Marcos Sánchez; Silvana Spagnoto; Patricia Martinez; Mario Gimenez

    2011-01-01

    Se realizó un estudio gravimétrico en la región norte de la cuenca Cuyana, entre las provincias de San Juan y Mendoza. Mediante relaciones de gradientes gravimétricos tales como señal analítica, Tilt y fase del Tilt, se observó un marcado gradiente, que fue interpretado como un cambio lateral de litologías, que coincidiría con el área de una probable paleosutura del margen proto-andino, que separa en el terreno compuesto de Cuyania, al terreno de Precordillera con el terreno de Pie de Palo.We...

  11. Abastecimiento y producción lítica en el sitio Valle Hermoso 1 (Malargüe, Mendoza) Lithic procurement and production in Valle Hermoso 1 Site, Malargüe, Mendoza

    OpenAIRE

    Gustavo Federico Bonnat

    2011-01-01

    En el presente texto se darán a conocer los resultados obtenidos del análisis del registro lítico del sitio Valle Hermoso 1 (Malargüe, provincia de Mendoza). El objetivo general de este trabajo es, desde una perspectiva organizacional de la tecnología, estudiar las estrategias de abastecimiento y producción lítica desarrolladas en el sitio por grupos cazadores-recolectores que habitaron el área de Valle Hermoso durante los últimos 2000 años. Los resultados obtenidos en el análisis del conjunt...

  12. High-brightness rf linear accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Jameson, R.A.

    1986-01-01

    The issue of high brightness and its ramifications in linacs driven by radio-frequency fields is discussed. A history of the RF linacs is reviewed briefly. Some current applications are then examined that are driving progress in RF linacs. The physics affecting the brightness of RF linacs is then discussed, followed by the economic feasibility of higher brightness machines. (LEW)

  13. The GM1 Ganglioside Forms GM1-Rich Gel Phase Microdomains within Lipid Rafts

    Directory of Open Access Journals (Sweden)

    Lucia Becucci

    2014-07-01

    Full Text Available Mercury-supported, self-assembled monolayers (SAMs of the sole dioleoylphosphatidylcholine (DOPC and of a raft-forming mixture of DOPC, cholesterol (Chol and palmitoylsphingomyelin (PSM of (59:26:15 mol% composition, were investigated by electrochemical impedance spectroscopy (EIS, both in the absence and in the presence of the monosialoganglioside GM1. The impedance spectra of these four SAMs were fitted by a series of parallel combinations of a resistance and a capacitance (RC meshes and displayed on plots of ωZ′ against −ωZ″, where Z′ and Z″ are the in-phase and quadrature components of the impedance and ω is the angular frequency. A comparison among these different impedance spectra points to the formation of GM1-rich gel phase microdomains within the lipid rafts of the DOPC/Chol/PSM mixture, thanks to the unique molecular-level smooth support provided by mercury, which allows EIS to detect the protruding gel phase microdomains by averaging them over a macroscopically large area.

  14. Applying a weed risk assessment approach to GM crops.

    Science.gov (United States)

    Keese, Paul K; Robold, Andrea V; Myers, Ruth C; Weisman, Sarah; Smith, Joe

    2014-12-01

    Current approaches to environmental risk assessment of genetically modified (GM) plants are modelled on chemical risk assessment methods, which have a strong focus on toxicity. There are additional types of harms posed by plants that have been extensively studied by weed scientists and incorporated into weed risk assessment methods. Weed risk assessment uses robust, validated methods that are widely applied to regulatory decision-making about potentially problematic plants. They are designed to encompass a broad variety of plant forms and traits in different environments, and can provide reliable conclusions even with limited data. The knowledge and experience that underpin weed risk assessment can be harnessed for environmental risk assessment of GM plants. A case study illustrates the application of the Australian post-border weed risk assessment approach to a representative GM plant. This approach is a valuable tool to identify potential risks from GM plants.

  15. Ecological Compatibility of GM Crops and Biological Control

    Science.gov (United States)

    Insect-resistant and herbicide-tolerant genetically modified (GM) crops pervade many modern cropping systems, and present challenges and opportunities for developing biologically-based pest management programs. Interactions between biological control agents (insect predators, parasitoids, and pathog...

  16. Risk, regulation and biotechnology: the case of GM crops.

    Science.gov (United States)

    Smyth, Stuart J; Phillips, Peter W B

    2014-07-01

    The global regulation of products of biotechnology is increasingly divided. Regulatory decisions for genetically modified (GM) crops in North America are predictable and efficient, with numerous countries in Latin and South America, Australia and Asia following this lead. While it might have been possible to argue that Europe's regulations were at one time based on real concerns about minimizing risks and ensuring health and safety, it is increasingly apparent that the entire European Union (EU) regulatory system for GM crops and foods is now driven by political agendas. Countries within the EU are at odds with each other as some have commercial production of GM crops, while others refuse to even develop regulations that could provide for the commercial release of GM crops. This divide in regulatory decision-making is affecting international grain trade, creating challenges for feeding an increasing global population.

  17. EDIBLE VACCINES FROM GM CROPS: CURRENT STATUS AND FUTURE SCOPE

    OpenAIRE

    2013-01-01

    The idea of an edible vaccine is coming closer to reality as scientists have found a way to incorporate the protein gene with some antigen in some plants. The major hurdles in the path of an emerging vaccine technology are being overcome. In this context, genetically modified (GM) plants are being investigated for the production of vaccines, antibodies and therapeutic proteins. The development of GM crops to produce drugs and vaccines has received considerable investment and is relatively wel...

  18. Public Acceptance of Plant Biotechnology and GM Crops

    OpenAIRE

    2015-01-01

    A wide gap exists between the rapid acceptance of genetically modified (GM) crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the divergent paths—also affecting the development of virus resistant transgenic crops—of political and regulatory frameworks for GM crops and food in different parts of the world. T...

  19. La obra lexicográfica de Manuel Hurtado de Mendoza: sus diccionarios enciclopédicos de medicina

    OpenAIRE

    Bertha M. Gutiérrez Rodilla

    2012-01-01

    [ES]La figura de Manuel Hurtado de Mendoza ya se ha analizado suficientemente en relación con sus aportaciones a la anatomía española de la primera mitad del siglo XIX o a la introducción en España de algunas novedades europeas. Sin embargo, todavía queda por estudiar buena parte de su obra, como ocurre con los diccionarios de medicina que compuso, dos enciclopédicos y uno terminológico. De los dos primeros nos ocupamos en este trabajo, en el que ponderaremos su importancia en ...

  20. La obra lexicográfica de Manuel Hurtado de Mendoza: sus diccionarios enciclopédicos de medicina

    OpenAIRE

    Bertha M. Gutiérrez Rodilla

    2012-01-01

    The figure of Manuel Hurtado de Mendoza has been sufficiently analyzed in connection with his contributions to Spanish anatomy during the first half of the 19th century or to the introduction of some European innovations in Spain. However, there is still much of his work to be studied, such as the medical dictionaries he wrote, two encyclopedic and one terminological. We deal with the first two in this essay, where we will speak highly of his significance in an age in which specialized lexico...

  1. Organización territorial urbana y transporte público masivo: Metrópolis del Gran Mendoza

    OpenAIRE

    María Emilia García Schilardi

    2015-01-01

    Existe acuerdo entre los expertos en transporte, planificación y urbanismo que la movilidad urbana es consecuencia de la organización espacial que adopta la ciudad y viceversa. Es decir, existe una estrecha relación entre las políticas de transporte y el ordenamiento del territorio. El objetivo de este trabajo es caracterizar la relación existente en la actualidad entre la organización territorial urbana de la zona del Gran Mendoza y el sistema de transporte masivo que opera en ella. Se estud...

  2. Geología de la región del Cerro Guanaquero, Río Diamante, Mendoza

    OpenAIRE

    Federico Fuentes; Ramos,Victor A.

    2008-01-01

    El estudio realizado presenta nuevos datos sobre un sector poco conocido de la Cordillera Principal de Mendoza, en la alta cuenca del río Diamante en las adyacencias del cerro Guanaquero, y los primeros datos geocronológicos de sus rocas volcánicas. Las unidades geológicas presentes en el área se dividen en cuatro grupos principales: secuencias sedimentarias mesozoicas marinas y continentales intensamente plegadas y falladas; intrusivos y volcanitas intermedias de edad neógena; rocas volcánic...

  3. Delivery of GM-CSF to Protect against Influenza Pneumonia.

    Directory of Open Access Journals (Sweden)

    Renuka Subramaniam

    Full Text Available Since adaptive immunity is thought to be central to immunity against influenza A virus (IAV pneumonias, preventive strategies have focused primarily on vaccines. However, vaccine efficacy has been variable, in part because of antigenic shift and drift in circulating influenza viruses. Recent studies have highlighted the importance of innate immunity in protecting against influenza.Granulocyte-macrophage colony stimulating factor (GM-CSF contributes to maturation of mononuclear phagocytes, enhancing their capacity for phagocytosis and cytokine production.Overexpression of granulocyte macrophage-colony stimulating factor (GM-CSF in the lung of transgenic mice provides remarkable protection against IAV, which depends on alveolar macrophages (AM. In this study, we report that pulmonary delivery of GM-CSF to wild type young and aged mice abrogated mortality from IAV.We also demonstrate that protection is species specific and human GM-CSF do not protect the mice nor stimulates mouse immunity. We also show that IAV-induced lung injury is the culprit for side-effects of GM-CSF in treating mice after IAV infection, and introduce a novel strategy to deliver the GM-CSF to and retain it in the alveolar space even after IAV infection.

  4. Biochemical characterization of GM1 micelles-Amphotericin B interaction.

    Science.gov (United States)

    Leonhard, Victoria; Alasino, Roxana V; Bianco, Ismael D; Garro, Ariel G; Heredia, Valeria; Beltramo, Dante M

    2015-01-01

    In this work a thorough characterization of the GM1 micelle-Amphotericin B (AmB) interaction was performed. The micelle formation as well as the drug loading occurs spontaneously, although influenced by the physicochemical conditions, pH and temperature. The chromatographic profile of GM1-AmB complexes at different molar ratios shows the existence of two populations. The differential absorbance of GM1, monomeric and aggregate AmB, allowed us to discriminate the presence of all of them in both fractions. Thus, we noted that at higher proportion of AmB in the complex, increases the larger population which is composed mainly of aggregated AmB. The physical behavior of these micelles shows that both GM1- AmB complexes were stable in solution for at least 30 days. However upon freeze-thawing or lyophilization-solubilization cycles, only the smallest population, enriched in monomeric AmB, showed a complete solubilization. In vitro, GM1-AmB micelles were significantly less toxic on cultured cells than other commercial micellar formulations as Fungizone, but had a similar behavior to liposomal formulations as Ambisome. Regarding the antifungal activity of the new formulation, it was very similar to that of other formulations. The characterization of these GM1-AmB complexes is discussed as a potential new formulation able to improve the antifungal therapeutic efficiency of AmB.

  5. Differential uPAR recruitment in caveolar-lipid rafts by GM1 and GM3 gangliosides regulates endothelial progenitor cells angiogenesis.

    Science.gov (United States)

    Margheri, Francesca; Papucci, Laura; Schiavone, Nicola; D'Agostino, Riccardo; Trigari, Silvana; Serratì, Simona; Laurenzana, Anna; Biagioni, Alessio; Luciani, Cristina; Chillà, Anastasia; Andreucci, Elena; Del Rosso, Tommaso; Margheri, Giancarlo; Del Rosso, Mario; Fibbi, Gabriella

    2015-01-01

    Gangliosides and the urokinase plasminogen activator receptor (uPAR) tipically partition in specialized membrane microdomains called lipid-rafts. uPAR becomes functionally important in fostering angiogenesis in endothelial progenitor cells (EPCs) upon recruitment in caveolar-lipid rafts. Moreover, cell membrane enrichment with exogenous GM1 ganglioside is pro-angiogenic and opposite to the activity of GM3 ganglioside. On these basis, we first checked the interaction of uPAR with membrane models enriched with GM1 or GM3, relying on the adoption of solid-supported mobile bilayer lipid membranes with raft-like composition formed onto solid hydrophilic surfaces, and evaluated by surface plasmon resonance (SPR) the extent of uPAR recruitment. We estimated the apparent dissociation constants of uPAR-GM1/GM3 complexes. These preliminary observations, indicating that uPAR binds preferentially to GM1-enriched biomimetic membranes, were validated by identifying a pro-angiogenic activity of GM1-enriched EPCs, based on GM1-dependent uPAR recruitment in caveolar rafts. We have observed that addition of GM1 to EPCs culture medium promotes matrigel invasion and capillary morphogenesis, as opposed to the anti-angiogenesis activity of GM3. Moreover, GM1 also stimulates MAPKinases signalling pathways, typically associated with an angiogenesis program. Caveolar-raft isolation and Western blotting of uPAR showed that GM1 promotes caveolar-raft partitioning of uPAR, as opposed to control and GM3-challenged EPCs. By confocal microscopy, we have shown that in EPCs uPAR is present on the surface in at least three compartments, respectively, associated to GM1, GM3 and caveolar rafts. Following GM1 exogenous addition, the GM3 compartment is depleted of uPAR which is recruited within caveolar rafts thereby triggering angiogenesis.

  6. Differential uPAR recruitment in caveolar-lipid rafts by GM1 and GM3 gangliosides regulates endothelial progenitor cells angiogenesis

    Science.gov (United States)

    Margheri, Francesca; Papucci, Laura; Schiavone, Nicola; D'Agostino, Riccardo; Trigari, Silvana; Serratì, Simona; Laurenzana, Anna; Biagioni, Alessio; Luciani, Cristina; Chillà, Anastasia; Andreucci, Elena; Del Rosso, Tommaso; Margheri, Giancarlo; Del Rosso, Mario; Fibbi, Gabriella

    2015-01-01

    Gangliosides and the urokinase plasminogen activator receptor (uPAR) tipically partition in specialized membrane microdomains called lipid-rafts. uPAR becomes functionally important in fostering angiogenesis in endothelial progenitor cells (EPCs) upon recruitment in caveolar-lipid rafts. Moreover, cell membrane enrichment with exogenous GM1 ganglioside is pro-angiogenic and opposite to the activity of GM3 ganglioside. On these basis, we first checked the interaction of uPAR with membrane models enriched with GM1 or GM3, relying on the adoption of solid-supported mobile bilayer lipid membranes with raft-like composition formed onto solid hydrophilic surfaces, and evaluated by surface plasmon resonance (SPR) the extent of uPAR recruitment. We estimated the apparent dissociation constants of uPAR-GM1/GM3 complexes. These preliminary observations, indicating that uPAR binds preferentially to GM1-enriched biomimetic membranes, were validated by identifying a pro-angiogenic activity of GM1-enriched EPCs, based on GM1-dependent uPAR recruitment in caveolar rafts. We have observed that addition of GM1 to EPCs culture medium promotes matrigel invasion and capillary morphogenesis, as opposed to the anti-angiogenesis activity of GM3. Moreover, GM1 also stimulates MAPKinases signalling pathways, typically associated with an angiogenesis program. Caveolar-raft isolation and Western blotting of uPAR showed that GM1 promotes caveolar-raft partitioning of uPAR, as opposed to control and GM3-challenged EPCs. By confocal microscopy, we have shown that in EPCs uPAR is present on the surface in at least three compartments, respectively, associated to GM1, GM3 and caveolar rafts. Following GM1 exogenous addition, the GM3 compartment is depleted of uPAR which is recruited within caveolar rafts thereby triggering angiogenesis. PMID:25313007

  7. Extensive Analysis of GmFTL and GmCOL Expression in Northern Soybean Cultivars in Field Conditions

    OpenAIRE

    2015-01-01

    The FLOWERING LOCUS T (FT) gene is a highly conserved florigen gene among flowering plants. Soybean genome encodes six homologs of FT, which display flowering activity in Arabidopsis thaliana. However, their contributions to flowering time in different soybean cultivars, especially in field conditions, are unclear. We employed six soybean cultivars with different maturities to extensively investigate expression patterns of GmFTLs (Glycine max FT-like) and GmCOLs (Glycine max CO-like) in the f...

  8. Graptolitos ordovícicos en el Sur de la Cordillera frontal de Mendoza

    Directory of Open Access Journals (Sweden)

    Hugo Tickyj

    2009-04-01

    Full Text Available En el flanco sudoriental de la Cordillera Frontal mendocina aflora un conjunto plegado de metasedimentitas conocido como Formación Las Lagunitas, cuyos afloramientos se extienden entre los ríos Diamante por el sur y Tunuyán por el norte, alcanzando un ancho máximo de 15 km a la latitud del volcán Maipo. El perfil estudiado en el arroyo Cortaderas (34º23'S está compuesto por una secuencia silicoclástica marina integrada por tres conjuntos litológicos, que de este a oeste son: a areniscas gruesas a medias, bien seleccionadas, y areniscas conglomerádicas, b vaques de grano grueso a fino y c areniscas finas a medias, con intercalaciones de pelitas negras laminadas. En la última unidad fueron colectados graptolitos en regular estado de preservación. Su estudio sistemático permitió definir una asociación correspondiente a la Biozona de Climacograptus bicornis, por lo que la Formación Las Lagunitas es asignada al Ordovícico Superior (Sandbiano o Caradociano. La completa extensión cronoestratigráfica de la Formación Las Lagunitas no ha sido establecida, debido a que en el perfil estudiado no es clara la relación entre la unidad portadora de graptolitos y el resto de la secuencia. Este registro de graptolitos en el sur de la Cordillera Frontal mendocina constituye un aspecto novedoso para el análisis del Ordovícico, con implicancias en el contexto de la evolución tectónica de las cuencas sedimentarias ordovícicas del oeste argentino.Outcrops of a folded sedimentary unit known as the Las Lagunitas Formation lie along the southeastern part of the Frontal Cordillera of Mendoza Province. The main exposures of the unit lie between the Diamante River in the south and Tunuyán in the north, reaching 15 km wide at the latitude of the Maipo volcano. At the Cortaderas Creek (34º23'S the studied section is a marine siliciclastic sequence comprising three lithological units: a well-sorted, coarse- to medium-grained sandstones and

  9. Evidencias de la zona de contacto entre los terrenos de Precordillera y Pie de Palo, Provincias de San Juan y Mendoza Evidence of the contact area between Precordillera and Pie de Palo terranes, Provinces of San Juan and Mendoza.

    Directory of Open Access Journals (Sweden)

    Maximiliano García Torrejón

    2011-12-01

    Full Text Available Se realizó un estudio gravimétrico en la región norte de la cuenca Cuyana, entre las provincias de San Juan y Mendoza. Mediante relaciones de gradientes gravimétricos tales como señal analítica, Tilt y fase del Tilt, se observó un marcado gradiente, que fue interpretado como un cambio lateral de litologías, que coincidiría con el área de una probable paleosutura del margen proto-andino, que separa en el terreno compuesto de Cuyania, al terreno de Precordillera con el terreno de Pie de Palo.We made the study in the northern Cuyo basin, between the provinces of San Juan and Mendoza. in the present work we show the results of gravimetric processing data from this basin and surrounding region. We applied anomaly-enhancement techniques such as analytic signal, tilt and phase of tilt. This allowed the observation of a marked gradient, which was interpreted as a lateral variation in lithology, which would coincides with the area of paleosuture of the proto-Andean margin, which separates in the Cuyania composite terrane the Precordillera from the Pie de Palo terranes.

  10. La doctrina sobre el poder del príncipe en Alfonso Hojeda de Mendoza

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    Salustiano de DIOS

    2009-12-01

    Full Text Available RESUMEN: Alfonso Hojeda fue un notable canonista sevillano que en 1576 publicó en Venecia un libro acerca de los beneficios eclesiásticos. La obra se divide en dos partes: la primera está dedicada a argumentar en contra de la pluralidad de beneficios en una misma persona, de acuerdo con los decretos tridentinos de reforma, mientras la segunda trata en cambio de la compatibilidad de beneficios mediante dispensa papal. Los propios términos en que se manifiestan las dos partes ya están indicando las contradicciones en que ha de moverse el autor, difíciles de salvar. La doctrina de la causa es, además de la distinción entre órdenes normativos, la principal herramienta conciliatoria para Hojeda. El papa está desligado del derecho positivo o humano, pues de otro modo no podría dispensar, o privilegiar, mas sólo puede hacerlo con justa causa.ABSTRACT: Alfonso Hojeda de Mendoza was an outstanding canonist that in 1576 published a book in Venice on the eclesiástica benefits. The book is divided into two parts: the first one is devoted to argue against the plurality of benefits in the same person, according to Trento's decrees, while the second one deals, however, with the compatibility of benefits by the Pope's dispense. The own terms in which both parts are expressed reveal the contradictions, in which the author must move, always difficult to avoid. The doctrine of the cause, as well as the distinction among normative orders, is the main conciliatory tool for Hojeda. The Pope is unlinked to human or positive right, otherwise he could not dispense or privilege, however he can only do it for a just cause.

  11. Relaciones biológicas entre las poblaciones tardías del sur de Mendoza

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    Barrientos, Gustavo

    2005-01-01

    Full Text Available En el presente, se encuentra en desarrollo un proyecto orientado a analizar la dinámica evolutiva de las poblaciones humanas de la porción central de Argentina y de Patagonia Continental durante el Holoceno, mediante la integración de diferentes líneas de evidencia morfológica (i.e. rasgos de variación continua y discontinua a nivel craneofacial, dental y postcraneal. El objetivo de este trabajo es presentar resultados parciales de esta investigación, obtenidos a partir del análisis del esqueleto craneofacial (morfometría geométrica y de piezas dentales permanentes (morfometría tradicional de 50 individuos adultos de ambos sexos, procedentes de sitios arqueológicos del Sur de Mendoza asignables a diferentes momentos del Holoceno tardío. Se registraron coordenadas de landmarks y semilandmarks sobre el esqueleto craneofacial en norma frontal y basilar y se relevaron los diámetros mesiodistal y bucolingual a nivel del cuello dental. Estas variables fueron empleadas en análisis de componentes principales. Los resultados obtenidos indican que, a nivel dental, se observó una diferenciación entre las muestras del Holoceno tardío inicial y final, caracterizándose las primeras por presentar mayores tamaños dentales. A nivel craneofacial también se observaron diferencias temporales, aunque con un patrón diferencial entre y dentro de cada sexo.

  12. Above-ground wineries and interior thermal stability: traditional and contemporary envelope analysis in Mendoza, Argentina

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    Carolina Ganem Karlen

    2013-06-01

    Full Text Available El control en el intercambio de flujos energéticos interior-exterior y la inercia térmica de los materiales constructivos son características claves de la envolvente de los edificios de bodegas. Esta situación es particularmente importante en el caso de los edificios construidos sobresuelo en climas con temperaturas diarias y estacionales muy variables. En el caso de que la arquitectura no provea la respuesta adecuada, indefectiblemente se recurre al consumo de energía auxiliar. La bodega S.A., ubicada en Mendoza, Argentina, consume energía auxiliar equivalente a 2.500 kW por año. Dicha bodega sobresuelo presenta dos tipos de envolvente vertical: una tradicional en adobe (λ = 0.81W/mK y otra contemporánea en chapa galvanizada sin aislación (λ = 45 W/mK. El objetivo de este trabajo es analizar los aspectos de materialidad, inercia térmica e intercambio de flujos energéticos de envolventes tradicionales y contemporáneas y, comparar los resultados obtenidos con un caso teórico de bodega subterránea. Entre los resultados obtenidos se observa que la envolvente tradicional mantiene las temperaturas interiores entre 8,5 ºC y 10 ºC por debajo de las temperaturas exteriores, mientras que los nuevos espacios con envolventes contemporáneas lo hacen solamente 3 ºC a 5 ºC por debajo de las temperaturas exteriores. En el caso de una bodega subterránea, las temperaturas estarían estables durante el año en 16,5 ºC; esto es, en verano, 20 ºC por debajo de las temperaturas exteriores.

  13. Controles estatales a la industria del vino en Mendoza, 1890-1914

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    PATRICIA BARRIO DE VILLANUEVA

    2013-05-01

    Full Text Available El artículo estudia los controles del Estado nacional y provincial a la agroindustria mendocina del vino entre la década de 1890 y 1914. En este período se detectan dos momentos. En el primero, entre 1890 y 1904, se analiza el mercado de vinos y cómo el Estado nacional utilizó los impuestos (aduaneros e internos para proteger a la naciente industria. También se reconstruye la legislación nacional y provincial que reguló la producción, la comercialización y el cobro de los impuestos al vino; y los mecanismos utilizados por ambas jurisdicciones para el cumplimiento de dichas leyes. En el segundo, se examinan los cambios ocurridos en la vitivinicultura durante los años de auge, entre 1904 y 1912, cuando los Estados provincial y nacional desplegaron estrictas normativas para evitar el fraude vínico y el pago del impuesto; y las primeras medidas tomadas con la llegada de una nueva crisis, entre 1913 y 1914. Abstract The article examines the controls of the national and provincial state to agribusiness Mendoza wine between the 1890 and 1914. In this period two points are detected. In the first, between 1890 and 1904, analyzes the wine market and how the national government used taxes (customs and internal to protect the nascent industry. Also reconstructs the national and provincial legislation that regulates the production, marketing and collection of taxes on wine, and the mechanisms used by both jurisdictions to comply with such laws. The second examines changes in the wine industry during the boom years between 1904 and 1912, when provincial and national States deployed strict standards to prevent wine fraud and tax payments, and the first steps taken with the arrival of a new crisis between 1913 and 1914.

  14. GmNAC30 and GmNAC81 integrate the endoplasmic reticulum stress- and osmotic stress-induced cell death responses through a vacuolar processing enzyme.

    Science.gov (United States)

    Mendes, Giselle C; Reis, Pedro A B; Calil, Iara P; Carvalho, Humberto H; Aragão, Francisco J L; Fontes, Elizabeth P B

    2013-11-26

    Prolonged endoplasmic reticulum and osmotic stress synergistically activate the stress-induced N-rich protein-mediated signaling that transduces a cell death signal by inducing GmNAC81 (GmNAC6) in soybean. To identify novel regulators of the stress-induced programmed cell death (PCD) response, we screened a two-hybrid library for partners of GmNAC81. We discovered another member of the NAC (NAM-ATAF1,2-CUC2) family, GmNAC30, which binds to GmNAC81 in the nucleus of plant cells to coordinately regulate common target promoters that harbor the core cis-regulatory element TGTG[TGC]. We found that GmNAC81 and GmNAC30 can function either as transcriptional repressors or activators and cooperate to enhance the transcriptional regulation of common target promoters, suggesting that heterodimerization may be required for the full regulation of gene expression. Accordingly, GmNAC81 and GmNAC30 display overlapping expression profiles in response to multiple environmental and developmental stimuli. Consistent with a role in PCD, GmNAC81 and GmNAC30 bind in vivo to and transactivate hydrolytic enzyme promoters in soybean protoplasts. A GmNAC81/GmNAC30 binding site is located in the promoter of the caspase-1-like vacuolar processing enzyme (VPE) gene, which is involved in PCD in plants. We demonstrated that the expression of GmNAC81 and GmNAC30 fully transactivates the VPE gene in soybean protoplasts and that this transactivation was associated with an increase in caspase-1-like activity. Collectively, our results indicate that the stress-induced GmNAC30 cooperates with GmNAC81 to activate PCD through the induction of the cell death executioner VPE.

  15. Review of Arciaga, Juárez y Mendoza (Coords. (2013. Introducción a la Psicología Social

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    Ali Lara

    2014-11-01

    Full Text Available Reseña del libro: Salvador Arciaga Bernal, Juana Juárez Romero y Jorge Mendoza Garcia  (coord. (2013. Introducción a la Psicología Social. México: UAM-MAPorrúa. ISBN 978-607-28-0109-7

  16. China, India Lead Asia Race on GM Crops

    Institute of Scientific and Technical Information of China (English)

    Dolly; Aglay; 谢丽英

    2000-01-01

    本文标题出现了GM Crops,用鼠标轻点其中的GM,竟然出现了“冈比亚”的释义!再查陆谷孙教授主编的《英汉大词典补编》,也没有见其踪影。其实,在文章的首段就可以找到GM Crops之释义:GM Crops=geneticallymodified crops。我想在不久的将来,英汉词典就会收入GM。当然,科技的发展永远领先于词典收入的新词。GM Crops如何译呢?可否译作“基因更改的农作物”?biotechnology(生物工艺学)和biosciences(生物科学)两个新词,前者已经收入了《英汉大词典补编》,后者尚有待收入。 本文向读者透露,当今世界并非一片为GM Crops大声叫好(a strong yes tobiotechnology)的声音: …grave concerns in Europe over the long-term environmental and healtheffects of genetically modified food. 在争论日趋激烈之时,本文亮出的观点是: …worries that GM crops may harm the environment or may not be safe tohealth have no scientific basis.

  17. The impact of different cooling strategies on urban air temperatures: the cases of Campinas, Brazil and Mendoza, Argentina

    Science.gov (United States)

    Alchapar, Noelia Liliana; Cotrim Pezzuto, Claudia; Correa, Erica Norma; Chebel Labaki, Lucila

    2016-07-01

    This paper describes different ways of reducing urban air temperature and their results in two cities: Campinas, Brazil—a warm temperate climate with a dry winter and hot summer (Cwa), and Mendoza, Argentina—a desert climate with cold steppe (BWk). A high-resolution microclimate modeling system—ENVI-met 3.1—was used to evaluate the thermal performance of an urban canyon in each city. A total of 18 scenarios were simulated including changes in the surface albedo, vegetation percentage, and the H/W aspect ratio of the urban canyons. These results revealed the same trend in behavior for each of the combinations of strategies evaluated in both cities. Nevertheless, these strategies produce a greater temperature reduction in the warm temperate climate (Cwa). Increasing the vegetation percentage reduces air temperatures and mean radiant temperatures in all scenarios. In addition, there is a greater decrease of urban temperature with the vegetation increase when the H/W aspect ratio is lower. Also, applying low albedo on vertical surfaces and high albedo on horizontal surfaces is successful in reducing air temperatures without raising the mean radiant temperature. The best combination of strategies—60 % of vegetation, low albedos on walls and high albedos on pavements and roofs, and 1.5 H/W—could reduce air temperatures up to 6.4 °C in Campinas and 3.5 °C in Mendoza.

  18. Minerales de mena del depósito epitermal de baja sulfuración Don Sixto, Mendoza

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    Ana Cecilia Mugas Lobos

    2012-03-01

    Full Text Available El proyecto minero Don Sixto es un depósito epitermal de baja sulfuración de Au-Ag, ubicado en el bloque de San Rafael, en el SE de la provincia de Mendoza. En este depósito, cuyo recurso aurífero es próximo a las 900.000 onzas, se ha identificado una asociación de minerales de metales preciosos que incluye: uytenbogaardtita, stromeyerita, naumannita, acantita, polibasita, stützita y cervelleita. Estos minerales son escasos y se encuentran frecuentemente asociados a oro y plata de variable fineza, diseminados en vetas de cuarzo hidrotermal y en unidades volcánicas-piroclásticas de los Grupos Choiyoi y El Portillo. En este depósito se encuentra abundante pirita, con cantidades menores de arsenopirita, calcopirita, esfalerita, magnetita, hematita y, en forma subordinada, pirrotina, galena, marcasita, bornita y boulangerita, junto con calcosina, digenita y covellina. La presencia de uytenbogaardtita, stützita, cervelleita y polibasita constituye la primera mención de estos minerales para la provincia de Mendoza.

  19. El temprano desarrollo de la vitivinicultura en Mendoza y en Canelones (1870-1930. Un análisis comparado

    Directory of Open Access Journals (Sweden)

    Daniele Bonfanti

    2005-01-01

    Full Text Available Starting from the end of XIX century, wine producing was a decisive factor in the process of modernization of Rio de la Plata area, contributing in differentiating the production and causing a fast industrialization in this particular field. Besides, local economies were revitalized by inserting them as specialized production areas in the national market. This article represents a first attempt of comparative analysis of the development of this field in two of the main wine producing areas in Rio de la Plata region: the Canelones department (Uruguay and Mendoza province (Argentine.A partir de finales del siglo XIX, la vitivinicultura cumplió un rol determinante en el proceso de modernización rioplatense contribuyendo a la diferenciación de la producción y provocando una rápida industrialización de un sector agrícola. Además, revitalizó a las economías locales, que se reinsertaron en los mercados nacionales como zonas especializadas. El artículo representa un primer intento de análisis comparativo del desempeño del sector en las dos principales áreas vitivinícolas rioplatenses: el departamento de Canelones (Uruguay y la provincia de Mendoza (Argentina.

  20. La obra lexicográfica de Manuel Hurtado de Mendoza: sus diccionarios enciclopédicos de medicina

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    Gutiérrez Rodilla, Bertha M.

    2012-12-01

    Full Text Available The figure of Manuel Hurtado de Mendoza has been sufficiently analyzed in connection with his contributions to Spanish anatomy during the first half of the 19th century or to the introduction of some European innovations in Spain. However, there is still much of his work to be studied, such as the medical dictionaries he wrote, two encyclopedic and one terminological. We deal with the first two in this essay, where we will speak highly of his significance in an age in which specialized lexicography took off in Europe, while it did not reach but a timid development in Spain.

    La figura de Manuel Hurtado de Mendoza ya se ha analizado suficientemente en relación con sus aportaciones a la anatomía española de la primera mitad del siglo XIX o a la introducción en España de algunas novedades europeas. Sin embargo, todavía queda por estudiar buena parte de su obra, como ocurre con los diccionarios de medicina que compuso, dos enciclopédicos y uno terminológico. De los dos primeros nos ocupamos en este trabajo, en el que ponderaremos su importancia en un siglo en que la lexicografía especializada despegó en Europa, mientras que en España no alcanzó más que un tímido desarrollo.

  1. How Bright Can Supernovae Get?

    Science.gov (United States)

    Kohler, Susanna

    2016-04-01

    Supernovae enormous explosions associated with the end of a stars life come in a variety of types with different origins. A new study has examined how the brightest supernovae in the Universe are produced, and what limits might be set on their brightness.Ultra-Luminous ObservationsRecent observations have revealed many ultra-luminous supernovae, which haveenergies that challenge our abilities to explain them usingcurrent supernova models. An especially extreme example is the 2015 discovery of the supernova ASASSN-15lh, which shone with a peak luminosity of ~2*1045 erg/s, nearly a trillion times brighter than the Sun. ASASSN-15lh radiated a whopping ~2*1052 erg in the first four months after its detection.How could a supernova that bright be produced? To explore the answer to that question, Tuguldur Sukhbold and Stan Woosley at University of California, Santa Cruz, have examined the different sources that could produce supernovae and calculated upper limits on the potential luminosities ofeach of these supernova varieties.Explosive ModelsSukhbold and Woosley explore multiple different models for core-collapse supernova explosions, including:Prompt explosionA stars core collapses and immediately explodes.Pair instabilityElectron/positron pair production at a massive stars center leads to core collapse. For high masses, radioactivity can contribute to delayed energy output.Colliding shellsPreviously expelled shells of material around a star collide after the initial explosion, providing additional energy release.MagnetarThe collapsing star forms a magnetar a rapidly rotating neutron star with an incredibly strong magnetic field at its core, which then dumps energy into the supernova ejecta, further brightening the explosion.They then apply these models to different types of stars.Setting the LimitThe authors show that the light curve of ASASSN-15lh (plotted in orange) can be described by a model (black curve) in which a magnetar with an initial spin period of 0.7 ms

  2. VERITAS Observations under Bright Moonlight

    CERN Document Server

    ,

    2015-01-01

    The presence of moonlight is usually a limiting factor for imaging atmospheric Cherenkov telescopes due to the high sensitivity of the camera photomultiplier tubes (PMTs). In their standard configuration, the extra noise limits the sensitivity of the experiment to gamma-ray signals and the higher PMT currents also accelerates PMT aging. Since fall 2012, observations have been carried out with VERITAS under bright moonlight (Moon illumination $> 35\\%$), in two observing modes, by reducing the voltage applied to the PMTs and with UV bandpass filters, which allow observations up to $\\sim80\\%$ Moon illumination resulting in $29\\%$ more observing time over the course of the year. In this presentation, we provide details of these new observing modes and their performance relative to the standard VERITAS observations.

  3. Constantly evolving safety assessment protocols for GM foods.

    Science.gov (United States)

    Sesikeran, B; Vasanthi, Siruguri

    2008-01-01

    he introduction of GM foods has led to the evolution of a food safety assessment paradigm that establishes safety of the GM food relative to its conventional counterpart. The GM foods currently approved and marketed in several countries have undergone extensive safety testing under a structured safety assessment framework evolved by international organizations like FAO, WHO, Codex and OECD. The major elements of safety assessment include molecular characterization of inserted genes and stability of the trait, toxicity and allergenicity potential of the expressed substances, compositional analysis, potential for gene transfer to gut microflora and unintentional effects of the genetic modification. As more number and type of food crops are being brought under the genetic modification regime, the adequacy of existing safety assessment protocols for establishing safety of these foods has been questioned. Such crops comprise GM crops with higher agronomic vigour, nutritional or health benefit/ by modification of plant metabolic pathways and those expressing bioactive substances and pharmaceuticals. The safety assessment challenges of these foods are the potential of the methods to detect unintentional effects with higher sensitivity and rigor. Development of databases on food compositions, toxicants and allergens is currently seen as an important aid to development of safety protocols. With the changing global trends in genetic modification technology future challenge would be to develop GM crops with minimum amount of inserted foreign DNA so as to reduce the burden of complex safety assessments while ensuring safety and utility of the technology.

  4. GM-CSF alters dendritic cells in autoimmune diseases.

    Science.gov (United States)

    Li, Bao-Zhu; Ye, Qian-Ling; Xu, Wang-Dong; Li, Jie-Hua; Ye, Dong-Qing; Xu, Yuekang

    2013-11-01

    Autoimmune diseases arise from an inappropriate immune response against self components, including macromolecules, cells, tissues, organs etc. They are often triggered or accompanied by inflammation, during which the levels of granulocyte macrophage colony-stimulating factor (GM-CSF) are elevated. GM-CSF is an inflammatory cytokine that has profound impact on the differentiation of immune system cells of myeloid lineage, especially dendritic cells (DCs) that play critical roles in immune initiation and tolerance, and is involved in the pathogenesis of autoimmune diseases. Although GM-CSF was discovered decades ago, recent studies with some new findings have shed an interesting light on the old hematopoietic growth factor. In the inflammatory autoimmune diseases, GM-CSF redirects the normal developmental pathway of DCs, conditions their antigen presentation capacities and endows them with unique cytokine signatures to affect autoimmune responses. Here we review the latest advances in the field, with the aim of demonstrating the effects of GM-CSF on DCs and their influences on autoimmune diseases. The summarized knowledge will help to design DC-based strategies for the treatment of autoimmune diseases.

  5. Regulatory control of genetically modified (GM) foods: likely developments.

    Science.gov (United States)

    Schilter, Benoît; Constable, Anne

    2002-02-28

    The placing of genetically modified (GM) crops on the European market requires a regulatory approval supported by a thorough safety evaluation. This approach has been applied to all GM crops presently on the market. Despite this stringent process there has been an increasing public concern about the impact of GM foods on human health and the environment. In this context, regulatory control may develop in several directions. One response to the public concern is to strengthen the data requirements for the risk assessment process. Several avenues have been proposed. They include the application of technologies such as proteomics and metabolomics to assess unintended changes, and the development of predictive methods to evaluate allergenicity. Obligations for post-launch surveillance have appeared in regulations. Criteria are required to define when and why such approaches are necessary. Significant challenges including feasibility and validation of the methods, and safety relevance of the data generated will have to be addressed before any general application of these new approaches. Effective monitoring requires the ability to identify the presence of GM products and trace their origin. Traceability and labeling are therefore important developments in the GM food regulatory arena. Both require the development of reliable analytical detection tools.

  6. The FMCA-GM assays, high throughput non-clonogenic alternatives to CFU-GM in preclinical hematotoxicity testing.

    Science.gov (United States)

    Haglund, Caroline; Aleskog, Anna; Håkansson, Lena Douhan; Höglund, Martin; Jacobsson, Stefan; Larsson, Rolf; Lindhagen, Elin

    2010-05-04

    One of the most common dose limiting adverse effects in cancer treatment is myelotoxicity. The aim of this study was to develop an in vitro method for measuring potential myelotoxic properties of a drug candidate in a high throughput setting. Human CD34(+) progenitor cells from umbilical cord blood were plated in 384-well microplates with drugs in liquid culture, supplemented with specific cytokines for the granulocytopoietic-macrophage lineage. After 7 or 14 days of proliferation and differentiation the cells were analyzed using the automated non-clonogenic fluorometric microculture cytotoxicity assay (FMCA). Two types of assays setups were evaluated, the FMCA-GM7 where cells were exposed to drugs directly after thawing and cytotoxicity measured on day 7 in contrast to the FMCA-GM14 where the cells were cultured 7 days prior to plating and drug exposure, with viability analysis on day 14 of differentiation. Drug sensitivity was similar in both assays and method validation was performed using 24 drugs with known myelotoxic profile (acyclovir, bortezomib, busulfan, carboplatin, chloramphenicol, chlorpromazine, cisplatin, cytarabine, clozapine, doxorubicin, erlotinib, etoposide, 5-fluorouracil, fludarabine, gefitinib, gemcitabine, hydroxyurea, imatinib, lomustine, melphalan, sorafenib, sunitinib, taxol and 6-thioguanine). The 50% inhibitory concentrations (IC(50)) from the FMCA-GM7 and the FMCA-GM14 correlated highly (r = 0.83) and (r = 0.82), respectively, with IC(50) from the established clonogenic assay (CFU-GM), obtained from the literature. The current data suggests that the FMCA-GM could offer a simple and robust alternative to the CFU-GM assay in preclinical hematotoxicity studies.

  7. Aftereffect of Adaptation to Illusory Brightness

    Directory of Open Access Journals (Sweden)

    Xinguang Cao

    2011-05-01

    Full Text Available Several figures are known to induce illusory brightness. We tested whether adaptation to illusory brightness produced an aftereffect in brightness. After viewing a gray square area having illusory brightness (e.g., due to brightness contrast or illusory contours for ten seconds, the illusion-inducing surround vanished. After three seconds, subjects reported whether the square area was seen as brighter than, darker than, or the same brightness as a control gray square area. The luminance of the tested square area was physically unchanged. The results show that when the black surround inducing brightness contrast suddenly became gray (i.e., vanished, the center gray square tended to look darker than a control gray square. Similarly, after viewing a subjective square consisting of black-line terminations, the square area tended to look darker than the control even though the afterimage of the lines could not be seen. These results indicate that induced or illusory brightness causes an aftereffect in brightness regardless of the appearance of negative afterimages of the illusion-inducing components.

  8. Eduardo Pérez Romagnoli; Los Guardianes de Baco. Artesanos toneleros e industrias de recipientes de vino en Mendoza y San Juan, Argentina (1885-1930, Rosario, Prohistoria ediciones, 2008

    Directory of Open Access Journals (Sweden)

    ANDRÉS CARMINATI

    2013-05-01

    Full Text Available Eduardo Pérez Romagnoli; Los Guardianes de Baco. Artesanos toneleros e industrias de recipientes de vino en Mendoza y San Juan, Argentina (1885-1930, Rosario, Prohistoria ediciones, 2008

  9. NMR-Metabolic Methodology in the Study of GM Foods

    Directory of Open Access Journals (Sweden)

    Irene D’Amico

    2010-01-01

    Full Text Available The 1H-NMR methodology used in the study of genetically modified (GM foods is discussed. Transgenic lettuce (Lactuca sativa cv "Luxor" over-expressing the Arabidopsis KNAT1 gene is presented as a case study. Twenty-two water-soluble metabolites (amino acids, organic acids, sugars present in leaves of conventional and GM lettuce were monitored by NMR and quantified at two developmental stages. The NMR spectra did not reveal any difference in metabolite composition between the GM lettuce and the wild type counterpart. Statistical analyses of metabolite variables highlighted metabolism variation as a function of leaf development as well as the transgene. A main effect of the transgene was in altering sugar metabolism.

  10. Recent development status of compact 2 K GM cryocoolers

    Science.gov (United States)

    Bao, Q.; Xu, M. Y.; Tsuchiya, A.; Li, R.

    2015-12-01

    To meet the growing demand for a compact cooling solution for superconducting electronic devices, we developed a two-stage 2 K GM cryocooler and a cryostat system, which can reach 46.3 K / 2.2 K on the first and second stages under no-load conditions. Nevertheless, with several innovative technologies applied, the total length of the expander cylinder is reduced to under 70% of the smallest conventional 4 K GM cryocooler. In this paper we will present the design method, including material selection and structure design with detailed explanation, which has been confirmed by both simulation and experiment.

  11. Generalized shrunken type-GM estimator and its application

    Science.gov (United States)

    Ma, C. Z.; Du, Y. L.

    2014-03-01

    The parameter estimation problem in linear model is considered when multicollinearity and outliers exist simultaneously. A class of new robust biased estimator, Generalized Shrunken Type-GM Estimation, with their calculated methods are established by combination of GM estimator and biased estimator include Ridge estimate, Principal components estimate and Liu estimate and so on. A numerical example shows that the most attractive advantage of these new estimators is that they can not only overcome the multicollinearity of coefficient matrix and outliers but also have the ability to control the influence of leverage points.

  12. Los Mares Interiores. (Libro de Poemas del Académico Juan Mendoza Vega

    Directory of Open Access Journals (Sweden)

    Efraim Otero Ruiz

    2001-12-01

    Full Text Available

    (Presentación del libro en la Fundación Santillana para Iberoamérica, Bogotá, Noviembre 23, 2001.

    Ha querido la deferencia del señor  exPresidente Belisario Betancur, Presidente de la Fundación Santillana para lberoamérica, que sea yo quien les presente el libro "Los mares interiores" del médico, periodista y poeta Juan Mendoza Vega. Tarea que acometo con singular afecto, nacido de una amistad que supera ya los 40 años y de una admiración continua por las dotes intelectuales y artísticas que lo colocan en un sitial especial entre los médicos de Colombia.

    Nacido en Chinácota y bachiller en Pamplona, su infancia y adolescencia transcurrieron en esos paisajes idílicos que se extienden entre el río Pamplonita y las colinas de Iscalá, donde ha trasegado la vida de muchos hijos ilustres del Norte de Santander. Después cursó sus estudios de Medicina en la Universidad
    Nacional, en Bogotá, entre 1952 y 1957, habiéndose graduado de médico en 1960 a los dos años de haber iniciado su especialización en neurología y neurocirugía, temas que constituirían la mayor dedicación de su vida. Pues de ahí saltó a la cátedra de la especialidad en la Facultad de Medicina del Rosario entre 1969 y 1985, siendo además iniciador de la cátedra y profesor de Historia de la Medicina en la misma Universidad desde 1980 hasta el presente; al tiempo, ha sido profesor de Etica Médica allí mismo desde 1983. A estas actividades de planta ha unido su participación como catedrático invitado en numerosas instituciones y universidades de dentro y fuera del país. Y la autoría de 55 publicaciones científicas en revistas nacionales e internacionales sobre temas de neurología y neurocirugía, ética médica e historia de la medicina...


  13. Efectos del Barrio La Gloria: Experiencias del lugar y estrategias simbólicas de los sectores populares en el Gran Mendoza Efeitos do "Barrio de La Gloria": As experiências do lugar e estratégias simbólicas das classes populares na Grande Mendoza Effects of "Barrio La Gloria": The "experience of place" and symbolic strategies of the popular classes in the Greater Mendoza

    Directory of Open Access Journals (Sweden)

    Magdalena Tosoni

    2011-12-01

    Full Text Available En este artículo describo las transformaciones en el espacio urbano y su relación con las desigualdades sociales y simbólicas en el Gran Mendoza. Las políticas de vivienda y los cambios en el mercado inmobiliario promovieron la suburbanización de los sectores populares y la jerarquización del territorio durante los últimos treinta años. A partir de un estudio de caso sobre el Barrio La Gloria ubicado en el sudeste del municipio de Godoy Cruz describo las " experiencias dellugar", es decir, cómo viven las desigualdades materiales y simbólicas los habitantes de un barrio popular del Gran Mendoza, y analizo las estrategias que ensayan las organizaciones para acumular capital simbólico en un área sentida como insegura por sus habitantes y calificada de "peligrosa" por la prensa.Neste artigo vou abordar as transformações no espaço urbano e os usos do local por setores populares e suas organizações na Grande Mendoza. As políticas de habitação e mudanças no mercado imobiliário têm promovido a suburbanização da classes média e popular, e da hierarquia dos territórios. A partir de um estudo de caso do Bairro La Gloria localizado na municipalidade de Godoy Cruz descrever a "experiência do lugar", ou seja, como vivem material e simbólica das desigualdades pessoas em cidade de Mendoza e analisar estratégias que as organizações de teste para acumular capital simbólico em uma área se sentiam inseguros para os seus habitantes e qualificados "perigoso" pela imprensa .In this article I search the transformations in urban space and the uses of the place by popular sectors and their organizations in the Greater Mendoza. Housing policies and changes in the housing market have caused the suburbanization of the middle and popular classes and hierarchy of the territories during the last thirty years. In this work we study the case of Barrio La Gloria is located in the southeastern city of Godoy Cruz, an area characterized by the

  14. Brightness Alteration with Interweaving Contours

    Directory of Open Access Journals (Sweden)

    Sergio Roncato

    2012-12-01

    Full Text Available Chromatic induction is observed whenever the perceived colour of a target surface shifts towards the hue of a neighbouring surface. Some vivid manifestations may be seen in a white background where thin coloured lines have been drawn (assimilation or when lines of different colours are collinear (neon effect or adjacent (watercolour to each other. This study examines a particular colour induction that manifests in concomitance with an opposite effect of colour saturation (or anti-spread. The two phenomena can be observed when a repetitive pattern is drawn in which outline thin contours intercept wider contours or surfaces, colour spreading appear to fill the surface occupied by surfaces or thick lines whereas the background traversed by thin lines is seen as brighter or filled of a saturated white. These phenomena were first observed by Bozzi (1975 and Kanizsa (1979 in figural conditions that did not allow them to document their conjunction. Here we illustrate various manifestations of this twofold phenomenon and compare its effects with the known effects of brightness and colour induction. Some conjectures on the nature of these effects are discussed.

  15. Bright Star Astrometry with URAT

    CERN Document Server

    Zacharias, Norbert

    2015-01-01

    The U.S. Naval Observatory Robotic Astrometric Telescope (URAT) is observing the northern sky since April 2012 for an astrometric survey. Multiple overlaps per year are performed in a single bandpass (680$-$750 nm) using the "redlens" 20 cm aperture astrograph and a mosaic of large CCDs. Besides the regular, deep survey to magnitude 18.5, short exposures with an objective grating are taken to access stars as bright as 3rd magnitude. A brief overview of the program, observing and reductions is given. Positions on the 8 to 20 mas level are obtained of 66,202 Hipparcos stars at current epochs. These are compared to the Hipparcos Catalog to investigate its accuracy. About 20\\% of the observed Hipparcos stars are found to have inconsitent positions with the Hipparcos Catalog prediction on the 3 sigma level or over (about 75 mas or more discrepant position offsets). Some stars are now seen at an arcsec (or 25 sigma) off their Hipparcos Catalog predicted position.

  16. Brightness and darkness as perceptual dimensions

    NARCIS (Netherlands)

    Vladusich, T.; Lucassen, M.P.; Cornelissen, F.W.

    2007-01-01

    A common-sense assumption concerning visual perception states that brightness and darkness cannot coexist at a given spatial location. One corollary of this assumption is that achromatic colors, or perceived grey shades, are contained in a one-dimensional (1-D) space varying from bright to dark. The

  17. SURFACE PHOTOMETRY OF LOW SURFACE BRIGHTNESS GALAXIES

    NARCIS (Netherlands)

    DEBLOK, WJG; VANDERHULST, JM; BOTHUN, GD

    1995-01-01

    Low surface brightness (LSB) galaxies are galaxies dominated by an exponential disc whose central surface brightness is much fainter than the value of mu(B)(0) = 21.65 +/- 0.30 mag arcsec(-2) found by Freeman. In this paper we present broadband photometry of a sample of 21 late-type LSB galaxies. Th

  18. Estrés nutricional, hipoplasia y explotación de recursos en el centro sur de Mendoza (Argentina Nutritional stress, enamel hypoplasia, and resource exploitation in south-central Mendoza

    Directory of Open Access Journals (Sweden)

    Paula Novellino

    2007-12-01

    Full Text Available Recientemente, se ha propuesto la existencia de un proceso de intensificación en la explotación de recursos para el alto valle del río Atuel durante los últimos 2000 años (Neme et al. 2005. Si bien se han registrado cambios similares en el resto del sur de Mendoza, han surgido algunos cuestionamientos sobre el reflejo arqueológico del mismo (Borrero 2002. Hasta el momento, la discusión de este problema había sido abordada desde el registro arqueofaunístico y desde los patrones de asentamiento (Neme 2002a, 2002b. En este trabajo, se presenta el estudio de las líneas de hipoplasia dental en los restos humanos de la región, como una línea de corroboración independiente para evaluar la existencia de estrés nutricional asociado a las etapas iniciales de un proceso de intensificación. Se presentan los resultados del análisis de 1505 piezas dentales permanentes en 128 individuos del centro sur de Mendoza, comparándose con estudios similares previos en la misma región y regiones vecinas. Se discute la tendencia cronológica de las hipoplasias registradas en el contexto de la intensificación propuesta. Los resultados no son concordantes con el estrés nutricional esperado y por ello se discuten explicaciones alternativas y problemas que podrían estar produciendo este patrón distinto al esperado.The existence of an intensification process in the exploitation of resources in the upper valley of the Atuel River during the last 2000 years has recently been proposed (Neme et al. 2005. Although similar changes have been registered in the rest of southern Mendoza, doubts about the archaeological record reflective of this process have arisen (Borrero 2002. Until now discussion of this problem had been approached from the archaeofaunal record and settlement patterns (Neme 2002a, 2002b. In this paper, the study of dental enamel hypoplasia in human remains of the region as an independent test to evaluate the existence of nutritional stress

  19. Galaxy selection and the surface brightness distribution

    CERN Document Server

    McGaugh, S S; Schombert, J M

    1995-01-01

    Optical surveys for galaxies are biased against the inclusion of low surface brightness (LSB) galaxies. Disney (1976) suggested that the constancy of disk central surface brightness noticed by Freeman (1970) was not a physical result, but instead was an artifact of sample selection. Since LSB galaxies do exist, the pertinent and still controversial issue is if these newly discovered galaxies constitute a significant percentage of the general galaxy population. In this paper, we address this issue by determining the space density of galaxies as a function of disk central surface brightness. Using the physically reasonable assumption (which is motivated by the data) that central surface brightness is independent of disk scale length, we arrive at a distribution which is roughly flat (\\ie approximately equal numbers of galaxies at each surface brightness) faintwards of the Freeman (1970) value. Brightwards of this, we find a sharp decline in the distribution which is analogous to the turn down in the luminosity ...

  20. The viticulture labor in Mendoza (Argentina during the capitalist modernization, 1880-1914 El mundo del trabajo vitivinícola en Mendoza (Argentina durante la modernización capitalista, 1880-1914

    Directory of Open Access Journals (Sweden)

    Rodolfo Richard-Jorba

    2009-01-01

    Full Text Available This paper outlines the development process of the capitalist viticulture in Mendoza. Using different primary and secondary sources, this study determines the composition of the viticulture labor and its quantitative and qualitative evolution. The introduction of up to date technology forced the training of manual labor with visible improvements in the workers' pay checks. This market became more complex through time showing multiple hierarchies in every rank of the work force, from peasants to wine makers. Several workers ascended the social ladder becoming managers due to diverse strategies traced through our various sources. Finally the workers' labor conditions indicate the vulnerability in which they were involved and their helplessness due to the lack of unions that could represent themEste artículo traza un breve panorama del proceso de desarrollo de la vitivinicultura capitalista en Mendoza y luego, utilizando diversas fuentes primarias y secundarias, determina la composición del mercado de trabajo vitivinícola y su evolución cuantitativa y cualitativa. La introducción de equipamiento técnico de avanzada obligó a la capacitación de la mano de obra con mejoras en los ingresos de los asalariados. Este mercado se complejizó con el tiempo y aparecieron múltiples jerarquías, desde el peón al enólogo o director técnico de las bodegas, pasando por los contratistas de viñas o los capataces. Muchos trabajadores ascendieron socialmente y se convirtieron en empresarios, en itinerarios que respondieron a diversas estrategias rastreables en las fuentes. Finalmente, las condiciones laborales que tuvieron los trabajadores muestran la precariedad en la que se desenvolvían y la indefensión en la que estaban inmersos por la ausencia de colectivos gremiales que asumieran la representación del trabajo frente al capital

  1. Public Acceptance of Plant Biotechnology and GM Crops

    Directory of Open Access Journals (Sweden)

    Jan M. Lucht

    2015-07-01

    Full Text Available A wide gap exists between the rapid acceptance of genetically modified (GM crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the divergent paths—also affecting the development of virus resistant transgenic crops—of political and regulatory frameworks for GM crops and food in different parts of the world. These have also shaped the different opinions of consumers. Important factors influencing consumer’s attitudes are the perception of risks and benefits, knowledge and trust, and personal values. Recent political and societal developments show a hardening of the negative environment for agricultural biotechnology in Europe, a growing discussion—including calls for labeling of GM food—in the USA, and a careful development in China towards a possible authorization of GM rice that takes the societal discussions into account. New breeding techniques address some consumers’ concerns with transgenic crops, but it is not clear yet how consumers’ attitudes towards them will develop. Discussions about agriculture would be more productive, if they would focus less on technologies, but on common aims and underlying values.

  2. Public Acceptance of Plant Biotechnology and GM Crops.

    Science.gov (United States)

    Lucht, Jan M

    2015-07-30

    A wide gap exists between the rapid acceptance of genetically modified (GM) crops for cultivation by farmers in many countries and in the global markets for food and feed, and the often-limited acceptance by consumers. This review contrasts the advances of practical applications of agricultural biotechnology with the divergent paths-also affecting the development of virus resistant transgenic crops-of political and regulatory frameworks for GM crops and food in different parts of the world. These have also shaped the different opinions of consumers. Important factors influencing consumer's attitudes are the perception of risks and benefits, knowledge and trust, and personal values. Recent political and societal developments show a hardening of the negative environment for agricultural biotechnology in Europe, a growing discussion-including calls for labeling of GM food-in the USA, and a careful development in China towards a possible authorization of GM rice that takes the societal discussions into account. New breeding techniques address some consumers' concerns with transgenic crops, but it is not clear yet how consumers' attitudes towards them will develop. Discussions about agriculture would be more productive, if they would focus less on technologies, but on common aims and underlying values.

  3. EU Regulations Impede Market Introduction of GM Forest Trees.

    Science.gov (United States)

    Custers, René; Bartsch, Detlef; Fladung, Matthias; Nilsson, Ove; Pilate, Gilles; Sweet, Jeremy; Boerjan, Wout

    2016-04-01

    Biotechnology can greatly improve the efficiency of forest tree breeding for the production of biomass, energy, and materials. However, EU regulations impede the market introduction of genetically modified (GM) trees so their socioeconomic and environmental benefits are not realized. European policy makers should concentrate on a science-based regulatory process.

  4. NMR-Metabolic Methodology in the Study of GM Foods

    Science.gov (United States)

    The 1H NMR methodology used in the study of genetically modified (GM) foodstuff is discussed. The study of transgenic lettuce (Lactuca sativa cv "Luxor") over-expressing the KNAT1 gene from Arabidopsis is presented as a novel study-case. The 1H NMR metabolic profiling was carried out. Twenty-two wat...

  5. Effects of GM crops on non-target organisms

    Science.gov (United States)

    Crop genetically engineered to provide resistance to specific groups of insect pests have been adopted by millions of growers throughout the world. GM crops have become important tools in crop production and protection in many countries and contribute significantly to overall IPM programs. There, ...

  6. The Environmental Benefits and Costs of Genetically Modified (GM) Crops

    NARCIS (Netherlands)

    Wesseler, J.H.H.; Scatasta, S.; Fall, E.H.

    2011-01-01

    The widespread introduction of genetically modified (GM) crops may change the effect of agriculture on the environment. The magnitude and direction of expected effects are still being hotly debated, and the interests served in this discussion arena are often far from those of science and social welf

  7. Desarrollo poblacional de Diaspidiotus perniciosus (Hemiptera: Diaspididae en cultivos de manzano de San Carlos, Mendoza, Argentina Population development of Diaspidiotus perniciosus (Hemiptera: Diaspididae in apple orchards in San Carlos, Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Guillermo P. Lopez Garcia

    2011-12-01

    Full Text Available Se estudió la bionomía de Diaspidiotus perniciosus Comstock ("escama de San José", en manzanos de la variedad "Red delicious" de San Carlos, Mendoza, Argentina, durante los ciclos productivos 2007-2008 y 2008-2009. Se determinó el número de generaciones anuales y se estudiaron las fluctuaciones poblacionales asociadas a la integral térmica para la especie en esta región. D. perniciosus presenta dos generaciones superpuestas al ciclo del cultivo, mientras que las ninfas (N1 y N2 de la tercera generación se desarrollan solamente hasta el final de la temporada estival y pasan al estado de quiescencia, en el que permanecen durante el invierno. El desarrollo de D. perniciosus en esta zona coincide con el de esta especie en la zona frutícola del centro de Chile en cuanto al número de generaciones y al periodo de quiescencia invernal. La población quiescente en Chile está integrada predominantemente por ninfas del primer estadio (N1, mientras que en San Carlos, Mendoza, la población quiescente está integrada principalmente por ninfas del segundo estadio (N2. La similitudes entre ambas poblaciones se deben, probablemente, a las coincidencias en latitud, clima y especie hospedera. El impacto económico de D. perniciosus en la zona de estudio tiene mayor relevancia durante los meses de diciembre y enero, cuando se observa una alta incidencia de daños en los frutos y las hojas; este es el momento decisivo para implementar medidas de control fitosanitario. Estas deberán aplicarse en función de los máximos poblacionales de N1 que se producen con 600-650 Grados-Día (ºD en diciembre y con 1.170-1.270ºD en enero. En las temporadas en las que la densidad poblacional de la plaga es especialmente alta, podrían incorporarse medidas adicionales de control con 1.800-2.000ºD durante el mes de abril. Los resultados de estos estudios representan una herramienta predictiva, que permitirá elaborar estrategias para el control de poblaciones de D

  8. Carretas y transporte terrestre bioceánico: la ruta Buenos Aires-Mendoza en el siglo XVIII

    Directory of Open Access Journals (Sweden)

    Lacoste, Pablo

    2005-01-01

    Full Text Available A carreta foi o principal meio de transporte terrestre na América colonial entre os séculos XVI e XIX. Uma das rotas mais utilizadas foi Buenos Aires-Mendoza, estabelecendo uma ligação entre os mercados do Atlântico e do Pacífico. Este artigo examina essas rotas, ao final do século XVIII, com base no processamento das viagens de 16. 000 carretas. O tema será aprofundado em um segundo trabalho intitulado "Los troperos y los orígenes de la burguesía en el Cono Sur de América colonial" (previsto para o próximo número de Estudos Ibero-Americanos

  9. Representaciones, turismo y Estado. Imágenes y discursos en torno de los paisajes culturales de Mendoza (Argentina

    Directory of Open Access Journals (Sweden)

    Cecilia Raffa

    2012-01-01

    Full Text Available En los últimos años, la provincia de Mendoza ha logrado consolidarse como uno de los principales destinos turísticos de Argentina: su paisaje la ha posicionado como lugar elegido por los turistas tanto nacionales como extranjeros. El trabajo que presentamos se propone refl exionar sobre los procesos dominantes que impulsaron la construcción del paisaje de la capital provincial, a través de la acción pública promovida por el Estado. Se analizan los procesos que los conducen, los actores que los encarnan y las imágenes resultantes que dan origen a la vez que nutren y renuevan las representaciones sociales sobre una ciudad que encuentra la clave de su identidad y gran parte de su desarrollo turístico, en el control y uso del agua.

  10. El tropero y el origen de la burguesía en el Cono Sur (Mendoza, siglo XVIII

    Directory of Open Access Journals (Sweden)

    Lacoste, Pablo

    2005-01-01

    Full Text Available Este artigo aprofunda a análise sobre a carreta e o tropeiro, para definir em que medida contribuíram para o processo de construção de uma cultura empresarial na América Colonial, levando ao surgimento de uma burguesia. Atenta-se, em especial, para temas como mobilidade social, riscos empresariais, fomento do crédito em confiança ou por hipoteca de carretas, circulação de idéias e configuração de um ethos capitalista. Este trabalho constitui a continuação e a conclusão de um anterior intitulado "Carretas y transporte terrestre bioceánico: la ruta Buenos Aires-Mendoza en el siglo XVIII" (Estudos Ibero-Americanos, vol. XXXI, nº 1, 2005

  11. Bright Streaks and Dark Fans

    Science.gov (United States)

    2007-01-01

    The south polar region of Mars is covered every year by a layer of carbon dioxide ice. In a region called the 'cryptic terrain,' the ice is translucent and sunlight can penetrate through the ice to warm the surface below. The ice layer sublimates (evaporates) from the bottom. The dark fans of dust seen in this image come from the surface below the layer of ice, carried to the top by gas venting from below. The translucent ice is 'visible' by virtue of the effect it has on the tone of the surface below, which would otherwise have the same color and reflectivity as the fans. Bright streaks in this image are fresh frost. The CRISM team has identified the composition of these streaks to be carbon dioxide. Observation Geometry Image PSP_003113_0940 was taken by the High Resolution Imaging Science Experiment (HiRISE) camera onboard the Mars Reconnaissance Orbiter spacecraft on 26-Mar-2007. The complete image is centered at -85.8 degrees latitude, 106.0 degrees East longitude. The range to the target site was 244.9 km (153.0 miles). At this distance the image scale is 49.0 cm/pixel (with 2 x 2 binning) so objects 147 cm across are resolved. The image shown here has been map-projected to 50 cm/pixel . The image was taken at a local Mars time of 06:20 PM and the scene is illuminated from the west with a solar incidence angle of 79 degrees, thus the sun was about 11 degrees above the horizon. At a solar longitude of 207.6 degrees, the season on Mars is Northern Autumn.

  12. Bright Sparks of Our Future!

    Science.gov (United States)

    Riordan, Naoimh

    2016-04-01

    My name is Naoimh Riordan and I am the Vice Principal of Rockboro Primary School in Cork City, South of Ireland. I am a full time class primary teacher and I teach 4th class, my students are aged between 9-10 years. My passion for education has developed over the years and grown towards STEM (Science, Technology, Engineering and Mathematics) subjects. I believe these subjects are the way forward for our future. My passion and beliefs are driven by the unique after school programme that I have developed. It is titled "Sparks" coming from the term Bright Sparks. "Sparks" is an after school programme with a difference where the STEM subjects are concentrated on through lessons such as Science, Veterinary Science Computer Animation /Coding, Eco engineering, Robotics, Magical Maths, Chess and Creative Writing. All these subjects are taught through activity based learning and are one-hour long each week for a ten-week term. "Sparks" is fully inclusive and non-selective which gives all students of any level of ability an opportunity to engage into these subjects. "Sparks" is open to all primary students in County Cork. The "Sparks" after school programme is taught by tutors from the different Universities and Colleges in Cork City. It works very well because the tutor brings their knowledge, skills and specialised equipment from their respective universities and in turn the tutor gains invaluable teaching practise, can trial a pilot programme in a chosen STEM subject and gain an insight into what works in the physical classroom.

  13. A probability index for surface zonda wind occurrence at Mendoza city through vertical sounding principal components analysis

    Science.gov (United States)

    Otero, Federico; Norte, Federico; Araneo, Diego

    2016-10-01

    The aim of this work is to obtain an index for predicting the probability of occurrence of zonda event at surface level from sounding data at Mendoza city, Argentine. To accomplish this goal, surface zonda wind events were previously found with an objective classification method (OCM) only considering the surface station values. Once obtained the dates and the onset time of each event, the prior closest sounding for each event was taken to realize a principal component analysis (PCA) that is used to identify the leading patterns of the vertical structure of the atmosphere previously to a zonda wind event. These components were used to construct the index model. For the PCA an entry matrix of temperature (T) and dew point temperature (Td) anomalies for the standard levels between 850 and 300 hPa was build. The analysis yielded six significant components with a 94 % of the variance explained and the leading patterns of favorable weather conditions for the development of the phenomenon were obtained. A zonda/non-zonda indicator c can be estimated by a logistic multiple regressions depending on the PCA component loadings, determining a zonda probability index widehat{c} calculable from T and Td profiles and it depends on the climatological features of the region. The index showed 74.7 % efficiency. The same analysis was performed by adding surface values of T and Td from Mendoza Aero station increasing the index efficiency to 87.8 %. The results revealed four significantly correlated PCs with a major improvement in differentiating zonda cases and a reducing of the uncertainty interval.

  14. Characterization of human lymphoid cell lines GM9947 and GM9948 as intra- and interlaboratory reference standards for DNA typing

    Energy Technology Data Exchange (ETDEWEB)

    Fregeau, C.J.; Elliott, J.C.; Fourney, R.M. [RCMP Central Forensic Laboratory, Ottawa, Ontario (Canada)] [and others

    1995-07-20

    The incorporation of reference DNA is crucial to the validation of any DNA typing protocol. Currently, reference DNA standards are restricted to molecular size DNA ladders and/or tumor cell line DNA. Either of these, however, presents some limitations. We have rigorously characterized two Epstein-Barr virus (EBV)-immortalized human lymphoid cell lines-GM9947 (female) and GM9948 (male)-to determine their suitability as alternative in-line standards for three widely employed allele profiling strategies. Twenty-one highly polymorphic VNTR-based allelic systems (7 RFLPs, 2 AmpFLPs, and 12 STRs) distributed over 12 chromosomes were scrutinized along with 3 gender-based discriminatory systems. The genetic stability of each locus was confirmed over a period of 225 in vitro population doublings. Allele size estimates and degree of informativeness for each of the 21 VNTR systems were compiled. The reproducibility of allele scoring by traditional RFLP analyses, using both cell lines as reference standards, was also verified by an interlaboratory validation study involving 13 analysts from two geographically distinct forensic laboratories. Taken together, our data indicate that GM9947 and GM9948 genomic DNAs could be adopted as reliable reference standards for DNA typing. 82 refs., 3 figs., 8 tabs.

  15. Space Brightness Evaluation for a Daylit Room

    Directory of Open Access Journals (Sweden)

    Takashi Maruyama

    2011-05-01

    Full Text Available One of the most important problems for lighting design is how to reduce an electric energy. One way to solve this problem is use of daylight, but little is known how to perceive a brightness of a room illuminated by daylight come in through a window and artificial light. Although the horizontal illuminance increases because of daylight, we would not perceive the room as bright as brightness estimated by the illuminance. The purpose of this study is to measure the space brightness for daylit room and to propose a evaluation method. The experiment was conducted with a couple of miniature office rooms, standard room and test room. Test room has several types of windows and standard room has no window. Subject was asked to evaluate the brightness of the test room relative to the standard room with method of magnitude estimation. It was found that brightness of daylit room did not increase simply with horizontal illuminance. Subject perceived a daylit room darker than a room illuminated only by the artificial light even if horizontal illuminance of these room was same. The effect of daylight on space brightness would vary with the window size and intensity of daylight or artificial light.

  16. Bright boys the making of information technology

    CERN Document Server

    Green, Tom

    2010-01-01

    Everything has a beginning. None was more profound-and quite as unexpected-than Information Technology. Here for the first time is the untold story of how our new age came to be and the bright boys who made it happen. What began on the bare floor of an old laundry building eventually grew to rival in size the Manhattan Project. The unexpected consequence of that journey was huge---what we now know as Information Technology. For sixty years the bright boys have been totally anonymous while their achievements have become a way of life for all of us. "Bright Boys" brings them home. By 1950 they'd

  17. GmFT2a and GmFT5a Redundantly and Differentially Regulate Flowering through Interaction with and Upregulation of the bZIP Transcription Factor GmFDL19 in Soybean

    OpenAIRE

    2014-01-01

    FLOWERING LOCUS T (FT) is the key flowering integrator in Arabidopsis (Arabidopsis thaliana), and its homologs encode florigens in many plant species regardless of their photoperiodic response. Two FT homologs, GmFT2a and GmFT5a, are involved in photoperiod-regulated flowering and coordinately control flowering in soybean. However, the molecular and genetic understanding of the roles played by GmFT2a and GmFT5a in photoperiod-regulated flowering in soybean is very limited. In this study, we d...

  18. Los territorios de la violencia en la novela policial y la narcoliteratura latinoamericana: Mario Mendoza, Peter Elmore y Alejandro Páez

    Directory of Open Access Journals (Sweden)

    Danilo Santos López

    2015-12-01

    Full Text Available El artículo expone la problemática de la violencia en las sociedades latinoamericanas a través de su representación en una serie de novelas publicadas a partir de los años noventa. Para ello se seleccionó las novelas policiales Enigma de los cuerpos (1995 de Peter Elmore, Satanás (2002 de Mario Mendoza y las narconovelas Corazón de Kalashnikov (2009, El reino de las moscas (2012 y Música para perros (2013 de Alejandro Páez Varela. Ellos son textos que recogen la situación de los personajes-víctimas de la novela criminalizada a través de la mirada narrativa sobre territorios muy delimitados como la Lima de Elmore, la Bogotá de Mendoza y Ciudad Juárez de Páez Varela.

  19. La desaparecida Capillade don Lope de Mendoza: nuevos datos sobre sus retablos, los sepulcros, su coro alto y la sacristía

    Directory of Open Access Journals (Sweden)

    Fernández González, Alberto

    2005-12-01

    Full Text Available Very little precise information remains on the exact characteristics of the no longer existing early medieval chapel founded by Archbishop Lope de Mendoza in the Cathedral of Santiago. Following the discovery of new documentary findings including descriptions, contracts, wills and a significant map of 1739, interesting facts about certain aspects of its architecture and tombs have been brought to light and, above all, we are able to reconstruct the furnishing of this important cathedral enclosure.

    De la desaparecida capilla bajomedieval que el arzobispo don Lope de Mendoza fundó en la catedral de Santiago apenas tenemos información precisa que permita conocer adecuadamente sus características. A partir del hallazgo de nuevas noticias documentales, que incluyen descripciones, contratos, testamentos y un significativo plano de 1739, se pueden aportar interesantes datos sobre algunos aspectos de su arquitectura y sepulcros y, sobre todo, reconstruir el amueblamiento de este importante recinto catedralicio.

  20. Analysis of the potential production and the development of bioenergy in the province of Mendoza - Bio-fuels and biomass - Using geographic information systems

    Energy Technology Data Exchange (ETDEWEB)

    Flores Marco, Noelia; Hilbert, Jorge Antonio [Instituto de Ingenieria Rural, INTA Las Cabanas y Los Reseros s/n, CP: 1712 Castelar, Buenos Aires (Argentina); Silva Colomer, Jorge [INTA EEA Junin Mendoza, Carril Isidoro Busquets s/n CP: 5572 (Argentina); Anschau, Renee Alicia; Carballo, Stella [Instituto de Clima y Agua, INTA. Las Cabanas y Los Reseros s/n, CP:1712 Castelar, Buenos Aires (Argentina)

    2010-06-15

    In this work, the partial results of the potential production of energy, starting from the biomass and the development of the crops, directed to the production of bio-fuels (Colza and Topinamur) in the North irrigation oasis of Mendoza, Argentina within the National Program of Bio-energy developed by INTA is presented. For the evaluation of the bio-energetic potential, derived from the biomass, the WISDOM methodology developed by FAO and implemented by INTA in Argentina was applied with the collaboration of national and provincial governmental entities that contribute local information The study of the potential production and the development of the bio-energetic crops have been carried out with the advising and participation of the experts of INTA of the studied crops. The province of Mendoza has semi-deserted agro-climatic characteristics. The type of soil and type of weather allows the production of great quality fruits and vegetables in the irrigated areas. The four great currents of water conform three oasis; Northeast, Center and South, which occupy the 3.67% of the surface of Mendoza. Today, Mendoza has 267,889 irrigated hectares, but the surface that was farmed by irrigation was near to the 400,000 ha. The climate contingencies, froze and hailstorm precipitations, plus the price instability cause great losses in the productive sector, taking it to the forlornness of the exploitations. The crop setting of these forlornness lands with crops directed to the production of bio-fuels and the utilization of the biomass coming from the agriculture activities and the agro industry (pruning of fruit trees, refuses of olive and vine, remnants of the peach industry, etc.) could assist the access to the energy in the rural areas, stimulating the economical improvement and the development in these communities. (author)

  1. The cultural heritage of the metropolitan area of Mendoza (Argentina). Methodological suggestions for their evaluation as a resource in local development project

    OpenAIRE

    Raffa, Cecilia; Conicet Argentina.; Cirvini, Silvia Augusta; Conicet Argentina.

    2014-01-01

    The research methodology proposal as presented, articulate and transfer of applied research results about EnvironmentalHeritage (pca) of the Metropolitan Area of Mendoza (amm). Our general hypothesis argues that the cultural heritage associatedwith the Territory (real estate: architectural, urban, landscape, with its accessories and environment) is a resource and a toolin local development processes, which in the case of the amm is not taken into account by the main actors involved. That is w...

  2. Brightness of synchrotron radiation from wigglers

    CERN Document Server

    Geloni, Gianluca; Saldin, Evgeni

    2014-01-01

    According to literature, while calculating the brightness of synchrotron radiation from wigglers, one needs to account for the so called `depth-of-field' effects. In fact, the particle beam cross section varies along the wiggler. It is usually stated that the effective photon source size increases accordingly, while the brightness is reduced. Here we claim that this is a misconception originating from an analysis of the wiggler source based on geometrical arguments, regarded as almost self-evident. According to electrodynamics, depth-of-field effects do not exist: we demonstrate this statement both theoretically and numerically, using a well-known first-principle computer code. This fact shows that under the usually accepted approximations, the description of the wiggler brightness turns out to be inconsistent even qualitatively. Therefore, there is a need for a well-defined procedure for computing the brightness from a wiggler source. We accomplish this task based on the use of a Wigner function formalism. I...

  3. Health effect of agricultural pesticide use in China: implications for the development of GM crops

    OpenAIRE

    Chao Zhang; Ruifa Hu; Jikun Huang; Xusheng Huang; Guanming Shi; Yifan Li; Yanhong Yin; Zhaohui Chen

    2016-01-01

    It is notable that the adoption of GM glyphosate-tolerant crops increases glyphosate use but reduces non-glyphosate herbicide use; and adoption of GM insect-resistant crops significantly reduces insecticide use. While the health hazard of pesticide use has been well documented, little literature evaluates the health effects of different pesticides related to GM crops in an integrated framework. This study aims to associate the uses of different pesticides related to GM crops with the blood ch...

  4. The analogy between stereo depth and brightness.

    Science.gov (United States)

    Brookes, A; Stevens, K A

    1989-01-01

    Apparent depth in stereograms exhibits various simultaneous-contrast and induction effects analogous to those reported in the luminance domain. This behavior suggests that stereo depth, like brightness, is reconstructed, ie recovered from higher-order spatial derivatives or differences of the original signal. The extent to which depth is analogous to brightness is examined. There are similarities in terms of contrast effects but dissimilarities in terms of the lateral inhibition effects traditionally attributed to underlying spatial-differentiation operators.

  5. Observations and diagnostics in high brightness beams

    Energy Technology Data Exchange (ETDEWEB)

    Cianchi, A., E-mail: alessandro.cianchi@roma2.infn.it [University of Rome Tor Vergata and INFN-Roma Tor Vergata, Via della Ricerca Scientifica 1, 00133 Rome (Italy); Anania, M.P.; Bisesto, F.; Castellano, M.; Chiadroni, E.; Pompili, R.; Shpakov, V. [INFN-LNF, Via Enrico Fermi 40, 00044 Frascati (Italy)

    2016-09-01

    The brightness is a figure of merit largely used in the light sources, like FEL (Free Electron Lasers), but it is also fundamental in several other applications, as for instance Compton backscattering sources, beam driven plasma accelerators and THz sources. Advanced diagnostics are essential tools in the development of high brightness beams. 6D electron beam diagnostics will be reviewed with emphasis on emittance measurement.

  6. A GM cryocooler with cold helium circulation for remote cooling

    Science.gov (United States)

    Wang, Chao; Brown, Ethan

    2014-01-01

    A GM cryocooler with new cold helium circulation system has been developed at Cryomech. A set of check valves connects to the cold heat exchanger to convert a small portion of AC oscillating flow in the cold head to a DC gas flow for circulating cold helium in the remote loop. A cold finger, which is used for remote cooling, is connected to the check valves through a pair of 5 m long vacuum insulated flexible lines. The GM cryocooler, Cryomech model AL125 having 120 W at 80 K, is employed in the testing. The cold finger can provide 50 W at 81 K for the power input of 4.1 kW and 70.5 W at 81.8 K for the power input of 6 kW. This simple and low cost design is very attractive for some applications in the near future.

  7. Do Russia and Eastern Europe need GM plants?

    Science.gov (United States)

    Skryabin, Konstantin

    2010-11-30

    Russia, Ukraine and Kazakhstan are the leading agricultural producers, especially for potato, sugar beet and sunflower. The cumulative effect of adverse climatic conditions, high weediness and losses related to viruses and pests (without any insecticide and herbicide treatments) led to losses amounting to 40-80% of potential production in the Russian Federation and other mentioned countries. We have used new biotechnology methods to obtain several crops (potato, sugar beet, sunflower and others) tolerant to abiotic and biotic stresses. For the first time - on the basis of domestic varieties bred by Russian scientists - GM potato varieties have been obtained, resistant to Colorado beetle. These GM potato varieties were recognised as being as safe as traditional ones and have been registered for food use. Using this technology, new biotechnological sugar beet lines tolerant to herbicides were also obtained.

  8. File list: Pol.Epd.10.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Epd.10.AllAg.Fibrobl_GM03348 hg19 RNA polymerase Epidermis Fibrobl GM03348 http...://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Pol.Epd.10.AllAg.Fibrobl_GM03348.bed ...

  9. File list: ALL.Epd.50.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Epd.50.AllAg.Fibrobl_GM03348 hg19 All antigens Epidermis Fibrobl GM03348 SRX189...394,SRX189398,SRX189393 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.Epd.50.AllAg.Fibrobl_GM03348.bed ...

  10. File list: DNS.Epd.05.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Epd.05.AllAg.Fibrobl_GM03348 hg19 DNase-seq Epidermis Fibrobl GM03348 SRX189394...,SRX189398,SRX189393 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Epd.05.AllAg.Fibrobl_GM03348.bed ...

  11. File list: Pol.Epd.05.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Epd.05.AllAg.Fibrobl_GM03348 hg19 RNA polymerase Epidermis Fibrobl GM03348 http...://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Pol.Epd.05.AllAg.Fibrobl_GM03348.bed ...

  12. File list: Pol.Epd.20.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Epd.20.AllAg.Fibrobl_GM03348 hg19 RNA polymerase Epidermis Fibrobl GM03348 http...://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Pol.Epd.20.AllAg.Fibrobl_GM03348.bed ...

  13. ANTI-GM1 ANTIBODIES IN PATIENTS WITH GUILLAIN-BARRE-SYNDROME

    NARCIS (Netherlands)

    VANDENBERG, LH; MARRINK, J; DEJAGER, AEJ; DEJONG, HJ; VANIMHOFF, GW; LATOV, N; SADIQ, SA

    1992-01-01

    Anti-GM1 antibodies were measured in 22 patients with the Guillain-Barre syndrome (GBS) and compared with anti-GM1 antibody activity in patients with other neurological or immunological diseases and in normal subjects. Four out of 22 patients with GBS had raised IgM, IgG, or IgA anti-GM1 antibody ac

  14. Picomolar inhibition of cholera toxin by a pentavalent ganglioside GM1os-calix[5]arene

    NARCIS (Netherlands)

    Garcia-Hartjes, J.; Bernardi, S.; Weijers, C.A.G.M.; Wennekes, T.; Gilbert, M.; Sansone, F.; Casnati, A.; Zuilhof, H.

    2013-01-01

    Cholera toxin (CT), the causative agent of cholera, displays a pentavalent binding domain that targets the oligosaccharide of ganglioside GM1 (GM1os) on the periphery of human abdominal epithelial cells. Here, we report the first GM1os-based CT inhibitor that matches the valency of the CT binding do

  15. 1+2〉2 LG GM730e

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    对于智能手机而言,新兴的操作界面已经逐渐取代了传统UI。对我们熟悉的Windows Mobile系统来说同样需要焕然一新的面貌,LG GM730e便集S-class 3D与Windows Mobile于一身闪亮登场。

  16. GM Crops, Organic Agriculture and Breeding for Sustainability

    Directory of Open Access Journals (Sweden)

    Salvatore Ceccarelli

    2014-07-01

    Full Text Available The ongoing debate about the use of genetically-modified (GM crops in agriculture has largely focused on food safety and genetic contamination issues. Given that the majority of GM crops have been produced to respond to the problem of crop yield reductions caused by diseases, insects and weeds, the paper argues that in those cases, the currently used GM crops are an unstable solution to the problem, because they represent such a strong selection pressure, that pests rapidly evolve resistance. Organic agriculture practices provide a more sustainable way of producing healthy food; however, the lower yields often associated with those practices, making the resultant healthy food more expensive, open the criticism that such practices will not be able to feed human populations. Evolutionary plant breeding offers the possibility of using the evolutionary potential of crops to our advantage by producing a continuous flow of varieties better adapted to organic systems, to climate change and to the ever changing spectrum of pests, without depending on chemical control.

  17. CFU-GM assay for evaluation of drug myelotoxic activity.

    Science.gov (United States)

    Pessina, Augusto; Bonomi, Arianna

    2007-11-01

    To study hematotoxicity of compounds on the myeloid cell compartment, the authors describe a standard procedure developed as a workable good laboratory practices-compliant protocol to determine the in vitro myelotoxic effect of drugs and chemicals. Specific protocols are presented to prepare human and murine myeloid progenitors (CFU-GM) for testing in a validated CFU-GM assay. Details are given for performing a screening test when toxicity data are not available and for passing on to an accurate inhibitory concentration-determination phase. To quantify the potential hematotoxicity of xenobiotics from their direct adverse effects on CFU-GM, the unit describes how to manage the results by means of an algorithm able to predict the acute xenobiotic exposure levels that cause maximum tolerated decreases (MTD) in absolute neutrophil count (ANC). A protocol describes a miniaturized application of the procedure in 96-well plates for high-throughput screening of compounds or for testing compounds that are available in very small quantities.

  18. Rincón del Atuel-1 (San Rafael, Mendoza: evidencias arqueológicas e implicancias regionales Rincon Del Atuel-1 (San Rafael, Mendoza: Archaeological Evidence And Regional Implications

    Directory of Open Access Journals (Sweden)

    Adolfo Gil

    2008-12-01

    Full Text Available El sitio Rincón del Atuel 1 (RA-1 fue uno de los primeros estudiado sistemáticamente en los inicios de la arqueología del sur de Mendoza y del que se conocía solo información proveniente de la superficie. Sobre la base de excavaciones recientes se detallan las evidencias arqueológicas del sitio. Asimismo se incorporan datos disponibles de colecciones previas. Sus ocupaciones se registran en los últimos 1500-1700 años AP y mostrarían dos momentos distintos; el más tardío desde hace unos 1000-1200 años AP y el otro desde esa fecha a unos 1500-1700 años AP. El conjunto más tardío se asocia a un suelo y mostraría características de "sitio somero" mientras que el conjunto inferior se relacionaría depositacionalmente con la planicie de inundación del río Atuel por lo que presentaría mejor resolución temporal. El registro arqueobotánico y los valores isotópicos en muestras humanas avalan una dieta mixta de maíz con otras plantas silvestres al menos para el conjunto más antiguo. La evidencia no es concordante con lo esperable para un patrón semi-sedentario o sedentario propuesto previamente para entender las ocupaciones agrícolas del área. Este registro es significativo para comprender la estructura arqueológica en valles fluviales de zonas áridas, y discutir temas como la intensificación regional y el significado de los cultígenos.Rincón del Atuel-1 is an open air archaeological site located in the current alluvial valley of the Atuel River, Mendoza Province (Argentina. The site was studied during the first stage of archaeological research in southern Mendoza. However, only the surface archaeological record was studied and no information was published about the material in stratigraphic context. Recently, excavations were carried out in order to explore issues related to the Late Holocene human occupation. The results presented here show that the site was occupied from 1500-1700 14C years BP until recently (at least ca

  19. Ultra-bright and -stable red and near-infrared squaraine fluorophores for in vivo two-photon imaging.

    Science.gov (United States)

    Podgorski, Kaspar; Terpetschnig, Ewald; Klochko, Oleksii P; Obukhova, Olena M; Haas, Kurt

    2012-01-01

    Fluorescent dyes that are bright, stable, small, and biocompatible are needed for high-sensitivity two-photon imaging, but the combination of these traits has been elusive. We identified a class of squaraine derivatives with large two-photon action cross-sections (up to 10,000 GM) at near-infrared wavelengths critical for in vivo imaging. We demonstrate the biocompatibility and stability of a red-emitting squaraine-rotaxane (SeTau-647) by imaging dye-filled neurons in vivo over 5 days, and utility for sensitive subcellular imaging by synthesizing a specific peptide-conjugate label for the synaptic protein PSD-95.

  20. Ultra-bright and -stable red and near-infrared squaraine fluorophores for in vivo two-photon imaging.

    Directory of Open Access Journals (Sweden)

    Kaspar Podgorski

    Full Text Available Fluorescent dyes that are bright, stable, small, and biocompatible are needed for high-sensitivity two-photon imaging, but the combination of these traits has been elusive. We identified a class of squaraine derivatives with large two-photon action cross-sections (up to 10,000 GM at near-infrared wavelengths critical for in vivo imaging. We demonstrate the biocompatibility and stability of a red-emitting squaraine-rotaxane (SeTau-647 by imaging dye-filled neurons in vivo over 5 days, and utility for sensitive subcellular imaging by synthesizing a specific peptide-conjugate label for the synaptic protein PSD-95.

  1. Las Órdenes religiosas en espacio urbano colonial - Mendoza (Argentina. El caso de la la Compañía de Jesús

    Directory of Open Access Journals (Sweden)

    Cirvini, Silvia A.

    2012-12-01

    Full Text Available The purpose of this article is to study the presence and the action of the regular clergy, in particular The Society of Jesus in Mendoza, which was a peripheral city and part of the Spanish empire in South America, from the urban history point of view. We recognize the Society of Jesus as a special and relevant character in Mendocinian colonial times because of the importance of their buildings and properties, their spatial location in the city and their connection with the community and the other members of the regular clergy. The Jesuits were the founders of the first school and the first public library. They were important providers of basic food such as beef and wheat, because they had an efficient network of productive establishments (farms, vineyards and mills devoted to agricultural and livestock farming. These farms were situated not only in the oasis of Mendoza but also in the Uco Valley (which is the oasis of the Tunuyán River.Este artículo propone abordar desde la perspectiva de la historia urbana, la presencia y la acción del clero regular, y en particular la Compañía de Jesús en Mendoza, ciudad periférica del Imperio español en el cono sur latinoamericano. Un recorrido de sus edificios y propiedades, su ubicación espacial en la ciudad, así como las conexiones con otros actores de la vida comunitaria y las otras órdenes religiosas nos permiten reconocer la manera en que la Compañía de Jesús se convirtió en un actor relevante del mundo colonial de Mendoza. Los jesuitas fueron los fundadores del primer colegio y la primera biblioteca pública que tuvo la ciudad, eran proveedores de alimentos básicos como la carne y el trigo ya que poseyeron una eficiente red de establecimientos productivos (haciendas, viñas y molinos dedicados a la actividad agrícola y ganadera, ubicados no sólo en el oasis del Río Mendoza sino también en el Valle de Uco (oasis del Río Tunuyán.

  2. Flujos de detritos recientes en la cordillera frontal de Mendoza: Un ejemplo de riesgo natural en la ruta 7 Recent debris flows in the Frontal Cordillera of Mendoza: an example of natural risk on the Road 7

    Directory of Open Access Journals (Sweden)

    Emmanuel Wick

    2010-06-01

    Full Text Available Se expone un estudio sobre los flujos de detritos ocurridos en enero de 2005, en el km 1.118,5 de la ruta nacional 7 en la provincia de Mendoza. La zona se ubica en la Cordillera Frontal, próxima al límite con la Precordillera. Se realizó un mapa geomorfológico detallado, sobre la base de una imagen Quickbird del año 2006. Además, se hicieron cálculos de volúmenes, velocidades y caudales, con mediciones en el campo y con ayuda de un sistema de información geográfico (SIG. El estudio de la geomorfología permitió proponer tres escenarios para el caso de un nuevo evento, a partir de los cuáles se creó un mapa de susceptibilidad a los flujos de detritos para el tramo de ruta analizado. Finalmente, se proponen medidas de protección y de mitigación ante la posibilidad de recurrencia de estos eventos en el sector.In this paper is presented a study dealing with the debris flows that reached the national road 7 in January 2005, in the km 1,118.5, Mendoza province. The area is located in the Frontal Cordillera near the limit of the Precordillera. A detailed geomorphologic map has been realized for this study using a Quickbird satellite imagery of the year 2006. Various calculations of volumes, velocities and peak discharges have been performed with the field data and using a geographic information system (GIS. The geomorphologic survey has permitted to propose three propagation scenarios in case of a new event. These allowed creating a map of debris flows susceptibility for the stretch of the road that has been studied. Finally, it has been proposed protection and mitigation measures, based on the results of the study, to protect the road from a new event.

  3. Plantas Fósiles del Grupo Choiyoi, Cordillera Frontal a la Latitud del río Mendoza Fossil plants from the Choiyoi Group, Frontal Cordillera at the latitude of the Mendoza River

    Directory of Open Access Journals (Sweden)

    Magdalena Koukharsky

    2011-06-01

    Full Text Available En este trabajo se dan a conocer los primeros restos fósiles hallados en sedimentitas, cuyo componente clástico es de origen volcánico, intercaladas en la Formación Tambillos del Grupo Choiyoi, Cordillera Frontal de Mendoza. Los mismos consisten en abundantes improntas de Sphenophyta en estado de preservación regular a malo. En la zona estudiada, las rocas de la Formación Tambillos, que son dominantemente volcánicas ácidas y de edad pérmica temprana a media según correlaciones regionales, se depositaron sobre una discordancia erosiva labrada en lavas andesíticas intensamente propilitizadas que se atribuyen a la Formación Portezuelo del Cenizo. Los restos vegetales se encuentran a unos 23 metros de la base, contenidos en niveles de areniscas finas y pelitas depositadas en un ambiente fluvial (microdelta, en los bordes de un lago y fueron coetáneas con los primeros episodios de volcanismo riolítico en la región. Si bien la flora encontrada no permite definir la edad, las formas presentes son comunes en niveles del Carbonífero superior-Pérmico y Triásico de Argentina.In this contribution we report the discovery of the first fossil remains in sedimentary strata belonging to the Tambillos Formation, Choiyoi Group, Cordillera Frontal of Mendoza. In the studied area the Tambillos Formation, which is formed dominantly by acid volcanics rocks of alleged Early to the Middle Permian, were deposited over an erosive unconformity on top of propilytic andesites of the Portezuelo del Cenizo Formation. The vegetal remains were found about 23 meters from the base of the formation, hosted in fine-grained sandstones and shales that were deposited in a fluvial environment (microdelta, along the borders of a lake during the first episodes of the rhyolitic volcanism of the region. The fossil flora includes abundant, poorly preserved impressions of Sphenophyta that does not permit to assign a precise age, although these forms are common in the Upper

  4. Developing GM super cassava for improved health and food security: future challenges in Africa

    Directory of Open Access Journals (Sweden)

    Adenle Ademola A

    2012-08-01

    Full Text Available Abstract Background There is an urgent need to solve the problem of micronutrient malnutrition that is prevalent among young children and women in Africa. Genetically modified (GM biofortified cassava has great potential to solve part of this problem, but controversy surrounding GM technology and lack of awareness, limited facilities, biased news and other factors may hinder the adoption of GM cassava in the future. Method Using semi-structured interviews in Ghana and Nigeria, this paper examines the perspectives of scientists, including the BioCassava Plus (BC+ team, on the potential adoption of GM cassava for improving health and food security in Africa. The article also examines issues around the regulatory system and transfer and acceptance of GM cassava among scientists. Results and discussion The result suggests that an overwhelming majority of scientists agree that GM biofortified cassava will benefit the health of millions in Africa, and that GM cassava conferred with disease and pest resistance will increase cassava production as it is currently plagued by cassava mosaic diseases (CMD. However, respondents are wary of long-term effects of GM cassava on the environment and lack of a regulatory framework to facilitate the adoption of GM cassava. Even though scientists expressed little or no concern about health risks of GM cassava, they were concerned that consumers may express such concerns given limited understanding of GM technology. Conclusion The article concludes with a summary of priorities for policy development with regard to adopting biofortified food products.

  5. Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease.

    Science.gov (United States)

    Kodama, Takashi; Togawa, Tadayasu; Tsukimura, Takahiro; Kawashima, Ikuo; Matsuoka, Kazuhiko; Kitakaze, Keisuke; Tsuji, Daisuke; Itoh, Kohji; Ishida, Yo-Ichi; Suzuki, Minoru; Suzuki, Toshihiro; Sakuraba, Hitoshi

    2011-01-01

    To find a new biomarker of Tay-Sachs disease and Sandhoff disease. The lyso-GM2 ganglioside (lyso-GM2) levels in the brain and plasma in Sandhoff mice were measured by means of high performance liquid chromatography and the effect of a modified hexosaminidase (Hex) B exhibiting Hex A-like activity was examined. Then, the lyso-GM2 concentrations in human plasma samples were determined. The lyso-GM2 levels in the brain and plasma in Sandhoff mice were apparently increased compared with those in wild-type mice, and they decreased on intracerebroventricular administration of the modified Hex B. The lyso-GM2 levels in plasma of patients with Tay-Sachs disease and Sandhoff disease were increased, and the increase in lyso-GM2 was associated with a decrease in Hex A activity. Lyso-GM2 is expected to be a potential biomarker of Tay-Sachs disease and Sandhoff disease.

  6. The interactome of soybean GmWRKY53 using yeast 2-hybrid library screening to saturation.

    Science.gov (United States)

    Tripathi, Prateek; Rabara, Roel C; Choudhary, Mani Kant; Miller, Marissa A; Huang, Ying-Sheng; Shen, Qingxi J; Blachon, Stéphanie; Rushton, Paul J

    2015-01-01

    Soybean GmWRKY53 functions in both biotic and abiotic stress signaling. Using GmWRKY53 as a bait yeast 2-hybrid library screening to saturation isolated multiple independent fragments for many interacting proteins, enabling delineation of minimal interacting domains and computation of a confidence score. Multiple independent clones coding for the LATE ELONGATED HYPOCOTYL clock protein GmLCL2 (MYB114) were isolated and the binding site for GmWRKY53 was mapped to 90 amino acids separate from the MYB domain. This suggests a direct input from the clock on GmWRKY53 activity. The GmWRKY53-interacting proteins also included 3 water stress-inducible AP2/ERF transcription factors. One of these (Glyma03g26310) is one of the most strongly water stress induced genes in soybean roots, suggesting that GmWRKY53/ERF complexes regulate water stress responses.

  7. Política habitacional comparada: Mendoza y San Luis en el marco de la descentralización

    Directory of Open Access Journals (Sweden)

    Delia Palero

    2006-01-01

    Full Text Available El artículo plantea un análisis comparado entre las políticas habitacionales desarrolladas por dos provincias argentinas: Mendoza y San Luis. La federalización de los recursos del FONAVI en el país, ocurrida en l992, puso fin a una prolongada etapa de política habitacional centralizada en Argentina. El período analizado abarca la década comprendida entre ese año y el 2002. A nivel internacional se consolida el proceso de globalización que, en el terreno de la vivienda, se tradujo en el predominio del enfoque facilitador. Los casos elegidos representan dos modelos diametralmente distintos que, sin embargo, alcanzaron resultados que podrían calificarse de exitosos en el concierto nacional. Mientras el primero se inscribe en el paradigma central-sectorial, el segundo adhiere en forma predominante al enfoque facilitador. El análisis de política comparada ha sido contextualizado en los escenarios político, social, cultural y económico que le dieron marco, sentido y viabilidad a ambos modelos, que marcaron tanto sus fortalezas como sus debilidades y que explican los resultados alcanzados. Vinculación con la formación universitaria: La Cátedra Problemática de la Vivienda se encuentra en la Facultad de Ciencias Políticas y Sociales (U.N.Cuyo e incluye en su programa unidades referidas a política habitacional en Argentina y en la provincia de Mendoza. En tal sentido, se estima que los resultados obtenidos a partir de este trabajo resultan un insumo de interés para estudiantes de trabajo social, sociología y ciencia política, en tanto permiten analizar en profundidad conceptos como centralizacióndescentralización, participación, articulación de actores, focalización, eficiencia y eficacia en la gestión de la política habitacional, entre otros, y cómo éstos se manifiestan en la práctica política concreta.

  8. Geomorphological and geophysical investigation of a complex rock glacier system - Morenas Coloradas valley (Cordon del Plata, Mendoza, Argentina)

    Science.gov (United States)

    Otto, Jan-Christoph; Götz, Joachim; Keuschnig, Markus; Hartmeyer, Ingo; Trombotto, Dario; Schrott, Lothar

    2010-05-01

    In the semi-arid high Andes of Argentina and Chile, rock glaciers are more frequent and often larger than glaciers. Aridity and high solar radiation hamper the development of large glaciers, favour permafrost conditions and the generation of rock glaciers. One of the few rock glaciers that have been studied in more detail since more than 20 years is located in the Cordon del Plata range about 60 km west of Mendoza, Argentina. The Morenas Coloradas rock glacier in the Rio Vallecitos catchment can be described as a multilobe, multiunit, multiroot and multipart rock glacier. It is a complex, transitional landform composed of a high altitude glaciated zone, which transforms into a debris covered glacier with thermokarst phenomena followed by various active rock glacier lobes and subsequently, inactive and relict lobes in the lower sections. Its total length is about 5 km. Complex transitional landforms between debris covered glaciers and rock glaciers are frequently observed in semi-arid mountain environments with high sediment production in periglacial areas like the Andes of Argentina but can be found also in other similar mountain ranges like for example Pamir, or Karakorum. However, the evolution and internal characteristics of such landforms are often unknown. Glacial and periglacial landforms of this size represent important water stores that play an essential role in water management and agriculture in the foreland of the Andes of Mendoza. In February 2008 subsurface conditions were investigated at three different altitudes using geophysical methods (ground penetrating radar, electric resistivity tomography). Complemented by digital geomorphological mapping we analyse the complex rock glacier ensemble, to gain insight into landform evolution, sediment flow structures and internal characteristics (permafrost occurrence, active layer depths, ice content, possible ice origin). Geophysical surveying at Morenas Coloradas clearly indicates the existence of frozen

  9. Geophysical studies applied to the exploration of the Aqua de las Liebres uranium deposit, Mendoza, Argentina; Estudios geofisicos en la exploracion de yacimientos de uranio Aqua de las Liebres, mendoza, Argentina

    Energy Technology Data Exchange (ETDEWEB)

    Pastore, Silvio Augusto; Rocco, Guillermo Felix E.; Ponti, Norberto [Instituto Sismologico F.S. Volponi (Argentina)

    1995-12-31

    The aim of this work was to apply a geophysical methodology, which let us make exploration studies of Uranium ore deposit, with good results and minimal costs. This technique will be used by the National Commission of Atomic Energy of Argentina (CNEA). This study was made at Agua de las Liebres site, Sierra Pintada-San Rafael-Mendoza, over an existing seismic path. Besides, there were three roles, digged up to the interesting level with a medium depth about 400 m. This investigation was made using the Vertical Electrical Sounding with a maximum AB = 3870 m. It could be used in the zone knowing that there were sub horizontal layered strata, with very important resistivity contrasts for its identification. The use of this methodology led us to obtain a more detailed knowledge of the existing geology, besides to take into account a helpful method, to increase the studied zones, optimizing ins such a way, the obtained results, found with another exploration techniques. (author). 4 refs., 4 figs., 4 tabs.

  10. Bright stars observed by FIMS/SPEAR

    CERN Document Server

    Jo, Young-Soo; Min, Kyoung-Wook; Choi, Yeon-Ju; Lim, Tae-Ho; Lim, Yeo-Myeong; Edelstein, Jerry; Han, Wonyong

    2015-01-01

    In this paper, we present a catalogue of the spectra of bright stars observed during the sky survey using the Far-Ultraviolet Imaging Spectrograph (FIMS), which was designed primarily to observe diffuse emissions. By carefully eliminating the contamination from the diffuse background, we obtain the spectra of 70 bright stars observed for the first time with a spectral resolution of 2--3 {\\AA} over the wavelength of 1370--1710 {\\AA}. The far-ultraviolet spectra of an additional 139 stars are also extracted with a better spectral resolution and/or higher reliability than those of the previous observations. The stellar spectral type of the stars presented in the catalogue spans from O9 to A3. The method of spectral extraction of the bright stars is validated by comparing the spectra of 323 stars with those of the International Ultraviolet Explorer (IUE) observations.

  11. Brightness discrimination in budgerigars (Melopsittacus undulatus.

    Directory of Open Access Journals (Sweden)

    Olle Lind

    Full Text Available Birds have excellent spatial acuity and colour vision compared to other vertebrates while spatial contrast sensitivity is relatively poor for unknown reasons. Contrast sensitivity describes the detection of gratings of varying spatial frequency. It is unclear whether bird brightness discrimination between large uniform fields is poor as well. Here we show that budgerigars (Melopsittacus undulatus need a Michelson contrast of 0.09 to discriminate between large spatially separated achromatic fields in bright light conditions. This is similar to the peak contrast sensitivity of 10.2 (0.098 Michelson contrast for achromatic grating stimuli established in earlier studies. The brightness discrimination threshold described in Weber fractions is 0.18, which is modest compared to other vertebrates.

  12. Increasing the brightness of light sources

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Ling

    2006-11-16

    In this work the principle of light recycling is applied to artificial light sources in order to achieve brightness enhancement. Firstly, the feasibilities of increasing the brightness of light sources via light recycling are examined theoretically, based on the fundamental laws of thermodynamics including Kirchhoff's law on radiation, Planck's law, Lambert-Beer's law, the etendue conservation and the brightness theorem. From an experimental viewpoint, the radiation properties of three different kinds of light sources including short-arc lamps, incandescent lamps and LEDs characterized by their light-generating mechanisms are investigated. These three types of sources are used in light recycling experiments, for the purpose of 1. validating the intrinsic light recycling effect in light sources, e. g. the intrinsic light recycling effect in incandescent lamps stemming from the coiled filament structure. 2. acquiring the required parameters for establishing physical models, e.g. the emissivity/absorptivity of the short-arc lamps, the intrinsic reflectivity and the external quantum efficiency of LEDs. 3. laying the foundations for designing optics aimed at brightness enhancement according to the characteristics of the sources and applications. Based on the fundamental laws and experiments, two physical models for simulating the radiance distribution of light sources are established, one for thermal filament lamps, the other for luminescent sources, LEDs. As validation of the theoretical and experimental investigation of the light recycling effect, an optical device, the Carambola, is designed for achieving deterministic and multiple light recycling. The Carambola has the function of a concentrator. In order to achieve the maximum possible brightness enhancement with the Carambola, several combinations of sources and Carambolas are modelled in ray-tracing simulations. Sources with different light-emitting mechanisms and different radiation properties

  13. GM as a route for delivery of sustainable crop protection.

    Science.gov (United States)

    Bruce, Toby J A

    2012-01-01

    Modern agriculture, with its vast monocultures of lush fertilized crops, provides an ideal environment for adapted pests, weeds, and diseases. This vulnerability has implications for food security: when new pesticide-resistant pest biotypes evolve they can devastate crops. Even with existing crop protection measures, approximately one-third yield losses occur globally. Given the projected increase in demand for food (70% by 2050 according to the UN), sustainable ways of preventing these losses are needed. Development of resistant crop cultivars can make an important contribution. However, traditional crop breeding programmes are limited by the time taken to move resistance traits into elite crop genetic backgrounds and the limited gene pools in which to search for novel resistance. Furthermore, resistance based on single genes does not protect against the full spectrum of pests, weeds, and diseases, and is more likely to break down as pests evolve counter-resistance. Although not necessarily a panacea, GM (genetic modification) techniques greatly facilitate transfer of genes and thus provide a route to overcome these constraints. Effective resistance traits can be precisely and conveniently moved into mainstream crop cultivars. Resistance genes can be stacked to make it harder for pests to evolve counter-resistance and to provide multiple resistances to different attackers. GM-based crop protection could substantially reduce the need for farmers to apply pesticides to their crops and would make agricultural production more efficient in terms of resources used (land, energy, water). These benefits merit consideration by environmentalists willing to keep an open mind on the GM debate.

  14. The historical investigation of cometary brightness

    Science.gov (United States)

    Hughes, David W.

    1998-12-01

    The interpretation of the way in which the brightness of a comet varied as a function of both its heliocentric and geocentric distance was essentially started by Isaac Newton in his book Philosophiae Naturalis Principia Mathematica, published in 1687. Astronomers have argued about the form of this variability ever since, and for many years it was regarded as an important clue as to the physical nature of the cometary nucleus and its decay process. This paper reviews our understanding of the causes of cometary brightness variability between about 1680 and the 1950s.

  15. GM crops and foods: what do consumers want to know?

    Science.gov (United States)

    McHughen, Alan

    2013-01-01

    Agricultural biotechnology--GMOs--has a huge positive impact on farming and farmers but remains controversial among the skeptical public. Curious but anxious consumers, driven by scare stories and pseudo-science provided by anti-GMO activists, seek accurate and authoritative answers to their questions. Here, I address a sample of such queries directed to me from the public, including the ubiquitous "Is it safe?" and also discuss some of the shameful tactics used by anti-GM activists in the public debate to garner support at the cost of inciting unnecessary anxiety among the public.

  16. Flujos de detritos recientes en la cordillera frontal de Mendoza: Un ejemplo de riesgo natural en la ruta 7

    Directory of Open Access Journals (Sweden)

    Emmanuel Wick

    2010-06-01

    Full Text Available Se expone un estudio sobre los flujos de detritos ocurridos en enero de 2005, en el km 1.118,5 de la ruta nacional 7 en la provincia de Mendoza. La zona se ubica en la Cordillera Frontal, próxima al límite con la Precordillera. Se realizó un mapa geomorfológico detallado, sobre la base de una imagen Quickbird del año 2006. Además, se hicieron cálculos de volúmenes, velocidades y caudales, con mediciones en el campo y con ayuda de un sistema de información geográfico (SIG. El estudio de la geomorfología permitió proponer tres escenarios para el caso de un nuevo evento, a partir de los cuáles se creó un mapa de susceptibilidad a los flujos de detritos para el tramo de ruta analizado. Finalmente, se proponen medidas de protección y de mitigación ante la posibilidad de recurrencia de estos eventos en el sector.

  17. Health and working conditions of high school and university teachers in Mendoza: between commitment and emotional distress

    Directory of Open Access Journals (Sweden)

    Patricia Alejandra Collado

    2016-06-01

    Full Text Available Con el objetivo de analizar los aspectos vinculados con la percepción sobre las condiciones de trabajo y su impacto en la salud de los docentes que pertenecen a la Universidad Nacional de Cuyo (UNCuyo, Mendoza, Argentina, este artículo analiza los resultados del Primer Censo de Condiciones y Salud Laboral, realizado a fines del año 2013, en dos unidades académicas (una de enseñanza media y otra de nivel universitario que abarcó a 193 docentes. El sondeo se dedicó a caracterizar el plantel de trabajadores/as y las condiciones que afectan su salud, principalmente en sus aspectos psicosociales, para lo cual se aplicó un cuestionario autoadministrado, cuyas dimensiones fueron debatidas en talleres de sensibilización con docentes que colaboraron en la preparación del instrumento de recolección. Entre sus principales resultados emerge el desgaste físico y emocional de trabajadores altamente calificados, por el efecto combinado de la respuesta comprometida a las exigencias de su labor con la degradación (material y simbólica de las condiciones en que la desempeña.

  18. Fission-track dating of the punta de vacas glaciation in the Rı´o Mendoza valley, Argentina.

    Science.gov (United States)

    Espizua, L. E.; Bigazzi, G.

    Fission-track dating of three tephra samples related to mappable drifts and non-glacial sediments, including alluvium, in the Rı´o Mendoza valley, Argentina, places limiting ages on the oldest two glacial events. A tephra-layer interstratified with fan alluvium that surrounds and cuts the outermost Uspallata moraine has an age of 170,000±50,000 yr, implying that the drift predates marine oxygen isotope stage (OIS) 6. A tephra dated at 134,000±32,000 yr, that was deposited on alluvial fan sediments, underlies Punta de Vacas drift, which is inferred to equate with Isotope Stage 6. The Punta de Vacas outwash, which likely correlates with the Rı´o Colorado drift, overlies another tephra unit that dates to 260,000±150,000 yr. Although the error limits of the dates preclude definitive correlations, all three tephra units may have been deposited during an interval prior to the maximum advance of the Punta de Vacas glaciation during OIS 6 or maybe in the Stage 7 interglacial period.

  19. The Cordon del Portillo Permian magmatism, Mendoza, Argentina, plutonic and volcanic sequences at the western margin of Gondwana

    Science.gov (United States)

    Gregori, Daniel; Benedini, Leonardo

    2013-03-01

    The Cerro Punta Blanca, Cerro Bayo and Cerro Punta Negra stocks, parts of the Cordillera Frontal Composite Batholith, cropping out in the Cordón del Portillo, records the Gondwana magmatic development of the Cordillera Frontal of Mendoza, in western Argentina. In this area, the San Rafael Orogenic phase, that represents the closure of the Late Carboniferous-Early Permian marine basins, begins at 284 Ma, and ceased before 276 Ma. The Cerro Punta Blanca, Cerro Bayo and Cerro Punta Negra stocks represent a post-orogenic magmatism and are equivalents to the Choiyoi Group. The Gondwana magmatic activity in the Cordón del Portillo area can be divided into two stages. The Cerro Punta Blanca stock (c.a. 276 Ma) represents an early post-orogenic, subduction-related magmatism similar to the basic-intermediate section of the Choiyoi Group (c.a. 277 Ma). The late post-orogenic second event was recorded by the Cerro Bayo (262 Ma) and Cerro Punta Negra stocks which represent a transition between subduction-related and intra-plate magmatism. This event represents the intrusive counterpart of the acidic facies of the upper section of the Choiyoi Group (c.a. 273 Ma). This extensional condition continued during the Triassic when the Cacheuta basin developed.

  20. Biodiversidad y TIC: experiencia de capacitación virtual para profesores de secundaria en la provincia de Mendoza, Argentina.

    Directory of Open Access Journals (Sweden)

    Gabriela Diaz Isenrath

    2015-12-01

    Full Text Available Educar para el conocimiento y conservación de la biodiversidad es complejo. Entre las numerosas estrategias didácticas disponibles, el uso de las TIC puede ser una poderosa herramienta para los procesos de enseñanza-aprendizaje. El curso virtual “Biodiversidad y TIC” se ofreció a través del portal educativo de la provincia de Mendoza, Argentina. Este fue parte de los cursos ofrecidos para la formación continua y permanente de docentes de secundaria. Los objetivos planteados fueron: generar una espacio de reflexión crítica sobre el uso de las TIC en la construcción de conceptos relacionados a la biodiversidad; brindar herramientas y materiales que promuevan actualización y contextualización regional de ideas centrales sobre la biodiversidad y su conservación y promover la innovación pedagógica. Se presenta la experiencia, su marco teórico, la organización del curso, los contenidos seleccionados y las estrategias utilizadas. Luego se analiza el proceso ocurrido en el aula virtual, y se plantean los logros y dificultades encontradas. Se proponen mejoras a implementar basadas en esta primera experiencia.

  1. Análisis del campo de esfuerzos en una secuencia lacustre de Precordillera oriental, San Juan-Mendoza

    Directory of Open Access Journals (Sweden)

    Laura P. Perucca

    2008-06-01

    Full Text Available En la quebrada del río Acequión, ubicada en el sur de la provincia de San Juan y norte de Mendoza (32º 10' S, en el centrooeste argentino, se efectuó el análisis de las fallas que afectan depósitos lacustres de edad holocena. Estas fallas se encuentran asociadas a estructuras de licuefacción y avalanchas de roca indicadoras de paleoterremotos, lo que permite extender el registro sísmico de la región hasta el Holoceno temprano. Al comparar el campo de esfuerzos regional actual (determinado por sismicidad instrumental, con el cálculo del mecanismo focal de los terremotos recientes ocurridos en la región con el campo de esfuerzos local, se observó que mientras el primero se caracteriza por la compresión, el campo local de la secuencia lacustre es extensional. Esto indicaría que aunque el esfuerzo regional actual es compresivo y de dirección NE-SO debido a la convergencia entre las placas de Nazca y Sudamérica, el antiguo lago adosado a las sierras de Pedernal y Los Pozos, está afectado por fallas normales, principalmente debido a esfuerzos locales distensivos originados por el reacomodamiento de estos depósitos durante el levantamiento de las zonas montañosas aledañas.

  2. Plantas Fósiles del Grupo Choiyoi, Cordillera Frontal a la Latitud del río Mendoza

    Directory of Open Access Journals (Sweden)

    Magdalena Koukharsky

    2011-06-01

    Full Text Available En este trabajo se dan a conocer los primeros restos fósiles hallados en sedimentitas, cuyo componente clástico es de origen volcánico, intercaladas en la Formación Tambillos del Grupo Choiyoi, Cordillera Frontal de Mendoza. Los mismos consisten en abundantes improntas de Sphenophyta en estado de preservación regular a malo. En la zona estudiada, las rocas de la Formación Tambillos, que son dominantemente volcánicas ácidas y de edad pérmica temprana a media según correlaciones regionales, se depositaron sobre una discordancia erosiva labrada en lavas andesíticas intensamente propilitizadas que se atribuyen a la Formación Portezuelo del Cenizo. Los restos vegetales se encuentran a unos 23 metros de la base, contenidos en niveles de areniscas finas y pelitas depositadas en un ambiente fluvial (microdelta, en los bordes de un lago y fueron coetáneas con los primeros episodios de volcanismo riolítico en la región. Si bien la flora encontrada no permite definir la edad, las formas presentes son comunes en niveles del Carbonífero superior-Pérmico y Triásico de Argentina.

  3. Capitalist modernization and poverty in Mendoza, Argentina. Agroindustrial development and working class life conditions, 1890-1918

    Directory of Open Access Journals (Sweden)

    Rodolfo Richard-Jorba

    2012-08-01

    Full Text Available During the last decade of the XIX century and the first two decades of the XX, the argentine province of Mendoza underwent substantial territorial, economical and society changes due to the advance of the capitalism, that formed one of the first regional economy of the country: the viticulture industry. The capitalist development produced an unknown economic expansion in which all the indicators increased in number: extent of the agrarian cultivation, wine vault installment, raise of the capacity of wine elaboration, technological improvement. Pertaining to society land subdivision, enterprise class arising and enlargement of the middle class. However, the majority of the popular sectors, enlarged by the overseas immigration, suffered life conditions characterized by low incomes which were maintained in face values during the studied period, and home and health problems that derived in the propagation of serious contagious disease and high children death rate. This article shows the contrast between a powerful productive forces development and the miserable conditions of population life.

  4. Organización territorial urbana y transporte público masivo: Metrópolis del Gran Mendoza

    Directory of Open Access Journals (Sweden)

    María Emilia García Schilardi

    2015-04-01

    Full Text Available Existe acuerdo entre los expertos en transporte, planificación y urbanismo que la movilidad urbana es consecuencia de la organización espacial que adopta la ciudad y viceversa. Es decir, existe una estrecha relación entre las políticas de transporte y el ordenamiento del territorio. El objetivo de este trabajo es caracterizar la relación existente en la actualidad entre la organización territorial urbana de la zona del Gran Mendoza y el sistema de transporte masivo que opera en ella. Se estudia, particularmente, la existencia o no de las condiciones urbanas que propenden al uso del transporte masivo, ya que se considera que éste es de fundamental importancia para el desarrollo sustentable de las ciudades. Con este fin se utiliza el modelo conceptual de ciudades orientadas al transporte masivo, propuesto por Julio Pozueta (2000, y se aplica al caso en estudio. Se revisan también trabajos de otros autores tanto los referidos a la zona analizada, como aquellos de carácter más general que dan luz sobre las tendencias urbanas en el mundo y en particular en las ciudades de Latinoamérica.

  5. VER Y SER VISTO: METÁFORA DE LA MIRADA EN EL PERRO DE ESCRIBANA, DE MARÍA LUISA MENDOZA It sees and is seen: scopic metaphor in El perro de la escribana by María Luisa Mendoza

    Directory of Open Access Journals (Sweden)

    Mariana Libertad Suárez

    2011-12-01

    Full Text Available Este artículo propone una lectura de la novela El perro de la escribana (1982 de María Luisa Mendoza, un texto donde la arbitrariedad y la voluntad del sujeto --o, lo que es lo mismo, “su mirada”-- se establecerán como herramientas básicas para arraigar las identidades nacionales, culturales y de género. Por lo mismo, el valor del pasado, así como el de los discursos asociados al mismo, dependerá únicamente de la autoridad simbólica de quienes los enuncien.This article proposes an analysis of the novel “El perro de la escribana” (1982 by Maria Luisa Mendoza, a text in which arbitrary and subject’s gaze will become basic tools where national, cultural and gender identities take root. In this book, its past depends only on the symbolic authority of those speeches outlining the memory.

  6. Fray Domingo de Mendoza y el convento de San Pedro Mártir de Las Palmas. Una aproximación historiográfica = Domingo de Mendoza and the convent of San Pedro Mártir de Las Palmas. A historiographical approach

    Directory of Open Access Journals (Sweden)

    Barrado Barquilla, José

    2016-01-01

    Full Text Available Resumen: Este nuevo estudio sobre los dominicos en Canarias, el segundo de los que hemos publicado hasta ahora, se centra en la figura de fray Domingo de Mendoza, uno de los principales artífices de la implantación de la Orden en el Nuevo Mundo (América y principalmente en las Islas Canarias, de cuyo convento de Las Palmas de Gran Canaria fue el fundador = Abstract: This new study on the Dominicans in the Canary Islands, the second we have published until now, it focuses on the figure of fray Domingo de Mendoza, one of the main architects of the implantation of the Order in the New World (America and principally in the Canary Islands, whose Las Palmas de Gran Canaria convento, was the founder.

  7. Soybean GmPHD-type transcription regulators improve stress tolerance in transgenic Arabidopsis plants.

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    Wei Wei

    Full Text Available BACKGROUND: Soybean [Glycine max (L. Merr.] is one of the most important crops for oil and protein resource. Improvement of stress tolerance will be beneficial for soybean seed production. PRINCIPAL FINDINGS: Six GmPHD genes encoding Alfin1-type PHD finger protein were identified and their expressions differentially responded to drought, salt, cold and ABA treatments. The six GmPHDs were nuclear proteins and showed ability to bind the cis-element "GTGGAG". The N-terminal domain of GmPHD played a major role in DNA binding. Using a protoplast assay system, we find that GmPHD1 to GmPHD5 had transcriptional suppression activity whereas GmPHD6 did not have. In yeast assay, the GmPHD6 can form homodimer and heterodimer with the other GmPHDs except GmPHD2. The N-terminal plus the variable regions but not the PHD-finger is required for the dimerization. Transgenic Arabidopsis plants overexpressing the GmPHD2 showed salt tolerance when compared with the wild type plants. This tolerance was likely achieved by diminishing the oxidative stress through regulation of downstream genes. SIGNIFICANCE: These results provide important clues for soybean stress tolerance through manipulation of PHD-type transcription regulator.

  8. Soybean GmDREBL Increases Lipid Content in Seeds of Transgenic Arabidopsis

    Science.gov (United States)

    Zhang, Yu-Qin; Lu, Xiang; Zhao, Fei-Yi; Li, Qing-Tian; Niu, Su-Ling; Wei, Wei; Zhang, Wan-Ke; Ma, Biao; Chen, Shou-Yi; Zhang, Jin-Song

    2016-01-01

    A DREB-type transcription factor gene GmDREBL has been characterized for its functions in oil accumulation in seeds. The gene is specifically expressed in soybean seeds. The GmDREBL is localized in nucleus and has transcriptional activation ability. Overexpression of GmDREBL increased the fatty acid content in the seeds of transgenic Arabidopsis plants. GmDREBL can bind to the promoter region of WRI1 to activate its expression. Several other genes in the fatty acid biosynthesis pathway were also enhanced in the GmDREBL-transgenic plants. The GmDREBL can be up-regulated by GmABI3 and GmABI5. Additionally, overexpression of GmDREBL significantly promoted seed size in transgenic plants compared to that of WT plants. Expression of the DREBL is at higher level on the average in cultivated soybeans than that in wild soybeans. The promoter of the DREBL may have been subjected to selection during soybean domestication. Our results demonstrate that GmDREBL participates in the regulation of fatty acid accumulation by controlling the expression of WRI1 and its downstream genes, and manipulation of the gene may increase the oil contents in soybean plants. Our study provides novel insights into the function of DREB-type transcription factors in oil accumulation in addition to their roles in stress response. PMID:27694917

  9. Brightness of synchrotron radiation from wigglers

    Science.gov (United States)

    Geloni, Gianluca; Kocharyan, Vitali; Saldin, Evgeni

    2016-01-01

    According to the literature, while calculating the brightness of synchrotron radiation from wigglers, one needs to account for the so-called 'depth-of-field' effects. In fact, the particle beam cross-section varies along the wiggler. It is usually stated that the effective photon source size increases accordingly, while the brightness is reduced. Here we claim that this is a misconception originating from an analysis of the wiggler source based on geometrical arguments, regarded as almost self-evident. According to electrodynamics, depth-of-field effects do not exist: we demonstrate this statement both theoretically and numerically, using a well-known first-principle computer code. This fact shows that under the usually accepted approximations, the description of the wiggler brightness turns out to be inconsistent even qualitatively. Therefore, there is a need for a well-defined procedure for computing the brightness from a wiggler source. We accomplish this task based on the use of a Wigner function formalism. We exemplify this formalism in simple limiting cases. We consider the problem of the calculation of the wiggler source size by means of numerical simulations alone, which play the same role of an experiment. We report a significant numerical disagreement between exact calculations and approximations currently used in the literature.

  10. Bright Future for Petroleum Development Cooperation

    Institute of Scientific and Technical Information of China (English)

    Zhang Zhenqing

    1996-01-01

    @@ China's oil prospects look bright, since reform and opening speed up. The oil production of 1995 is 148 million tons and the confirmed reserves of oil and gas only occupy one-fifth of those possible to be verified, the petroleum exploration will be deepened to locate and confirm the remaining reserves.

  11. Dark Matter in Low Surface Brightness Galaxies

    NARCIS (Netherlands)

    Blok, W. J. G. de; McGaugh, S. S.

    1996-01-01

    Abstract: Low Surface Brightness (LSB) galaxies form a large population of disc galaxies that extend the Hubble sequence towards extreme late-types. They are only slowly evolving, and still in an early evolutionary state. The Tully-Fisher relation and rotation curves of LSB galaxies both show that L

  12. Dark matter in low surface brightness galaxies

    NARCIS (Netherlands)

    de Blok, WJG; McGaugh, SS; Persic, M; Salucci, P

    1997-01-01

    Low Surface Brightness (LSB) galaxies form a large population of disc galaxies that extend the Hubble sequence towards extreme late-types. They are only slowly evolving, and still in an early evolutionary state. The Tully-Fisher relation and rotation curves of LSB galaxies both show that LSB galaxie

  13. A photometric investigation of a bright Geminid

    NARCIS (Netherlands)

    Degewij, J.; Diggelen, Johannes van

    1968-01-01

    Photographic observations of meteors in the Netherlands started with a bright Geminid of photographic magnitude −8 observed on December 11, 1955, 21h39m55s by M. Alberts. From the assumed radiant and velocity we have constructed the trajectory of the bolide. The luminosity of the trail has been dete

  14. Investigation on the magnetomechanical behavior of trilayered GM actuator

    Institute of Scientific and Technical Information of China (English)

    Heung-Shik Lee; Chongdu Cho

    2008-01-01

    In this article, it was suggested a TbFe/Co/Dy trilayered GM (Giant Magnetostrictive) film type actuator and investigated the magnetomechanical characteristics of the actuator for micro application. The trilayered films were fabricated at different thickness ratios to get an optimized structure. TbFe had positive GM properties, and cobalt, dysprosium layers made the magnetostriction property of composite film increase in low magnetic field. To fabricate the Si based microactuator with trilayered film, micromachining processes including RIE (Reactive Ion Etching) and selective DC magnetron sputtering techniques were combined. The deposited film thicknesses were measured by X-ray diffraction (XRD). As a result, the magnetization of the film on the fabricated actuator was observed to characterize the magnetic properties of the TbFe/Co/Dy film using VSM (Vibrating Sample Magnetometer). The magnetostriction of the actuator was determined by measuring the differences of curvature of the film coated silicon substrates using the optical cantilever method, and the deflections were also estimated under the external magnetic field lower than 0.5T for micro-system applications.

  15. Alberta Associations for Bright Children Members' Handbook.

    Science.gov (United States)

    Alberta Association for Bright Children, Edmonton.

    This handbook is designed to provide information to parents of gifted children in Alberta, Canada. The handbook outlines the mission and objectives of the Alberta Associations for Bright Children and describes the structure of the non-profit organization. The booklet then addresses: (1) the characteristics of gifted children; (2) the rights of…

  16. Brightness and darkness as perceptual dimensions.

    Directory of Open Access Journals (Sweden)

    Tony Vladusich

    2007-10-01

    Full Text Available A common-sense assumption concerning visual perception states that brightness and darkness cannot coexist at a given spatial location. One corollary of this assumption is that achromatic colors, or perceived grey shades, are contained in a one-dimensional (1-D space varying from bright to dark. The results of many previous psychophysical studies suggest, by contrast, that achromatic colors are represented as points in a color space composed of two or more perceptual dimensions. The nature of these perceptual dimensions, however, presently remains unclear. Here we provide direct evidence that brightness and darkness form the dimensions of a two-dimensional (2-D achromatic color space. This color space may play a role in the representation of object surfaces viewed against natural backgrounds, which simultaneously induce both brightness and darkness signals. Our 2-D model generalizes to the chromatic dimensions of color perception, indicating that redness and greenness (blueness and yellowness also form perceptual dimensions. Collectively, these findings suggest that human color space is composed of six dimensions, rather than the conventional three.

  17. Probable Bright Supernova discovered by PSST

    Science.gov (United States)

    Smith, K. W.; Wright, D.; Smartt, S. J.; Young, D. R.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-09-01

    A bright transient, which is a probable supernova, has been discovered as part of the Pan-STARRS Survey for Transients (PSST). Information on all objects discovered by the Pan-STARRS Survey for Transients is available at http://star.pst.qub.ac.uk/ps1threepi/ (see Huber et al. ATel #7153).

  18. Picomolar inhibition of cholera toxin by a pentavalent ganglioside GM1os-calix[5]arene.

    Science.gov (United States)

    Garcia-Hartjes, Jaime; Bernardi, Silvia; Weijers, Carel A G M; Wennekes, Tom; Gilbert, Michel; Sansone, Francesco; Casnati, Alessandro; Zuilhof, Han

    2013-07-14

    Cholera toxin (CT), the causative agent of cholera, displays a pentavalent binding domain that targets the oligosaccharide of ganglioside GM1 (GM1os) on the periphery of human abdominal epithelial cells. Here, we report the first GM1os-based CT inhibitor that matches the valency of the CT binding domain (CTB). This pentavalent inhibitor contains five GM1os moieties linked to a calix[5]arene scaffold. When evaluated by an inhibition assay, it achieved a picomolar inhibition potency (IC50 = 450 pM) for CTB. This represents a significant multivalency effect, with a relative inhibitory potency of 100,000 compared to a monovalent GM1os derivative, making GM1os-calix[5]arene one of the most potent known CTB inhibitors.

  19. Comparative Analysis of Two Industries for Validating Green Manufacturing (GM) Framework: An Indian Scenario

    Science.gov (United States)

    Rehman, Minhaj Ahemad Abdul; Shrivastava, Rakesh Lakshmikumar; Shrivastava, Rashmi Rakesh

    2016-07-01

    Green Manufacturing (GM) deals with manufacturing practices that reduces or eliminates the adverse environmental impact during any of its phases. It emphasizes the use of processes that do not contaminate the environment or hurt consumers, employees, or other stakeholders. This paper presents the comparative analysis of two Indian industries representing different sectors for validating GM framework. It also highlights the road map of the companies for achieving performance improvement through GM implementation and its impact on organisational performance. The case studies helps in evaluating the companies GM implementation and overall business performance. For this, a developed diagnostic instrument in the form of questionnaire was administered amongst employees in the companies respectively and their responses were analysed. In order to have a better understanding of the impact of GM implementation, the information about overall business performance was obtained over the last 3 years. The diagnostic instrument developed here may be used by manufacturing organisations to prioritise their management efforts to assess and implement GM.

  20. Conflictos sociales en Mendoza entre dos crisis, 1890-1916: Una larga lucha de los trabajadores por la conquista de sus derechos laborales

    Directory of Open Access Journals (Sweden)

    Rodolfo Richard-Jorba

    2010-06-01

    Full Text Available Este artículo contribuye a la reconstrucción de la historia del mundo de los trabajadores en Mendoza. Las fuentes revisadas y la sistematización de información dispersa han permitido profundizar en los conocimientos hasta ahora generados, sacando a luz una parte significativa del desarrollo capitalista centrado en la agroindustria vitivinícola. Las fuentes principales para seguir los conflictos han sido los diarios mendocinos, por lo que nuestro abordaje constituye una aproximación que esperamos poder ampliar en el futuro. En este artículo presentamos los conflictos sociales en el contexto de períodos de crisis y de auge económico. Comenzamos por la crisis de 1890 y concluimos con la crisis provocada por la Primera Guerra Mundial y los cambios políticos que sobrevendrían a partir de 1916-1918This article contributes to reconstructing the history of the world of labour in Mendoza. The revision of sources and the systematization of the scattered information available resulted in a deeper insight on the subject and a better understanding of capitalist development based on vitivicultural agroindustry. Articles from Mendoza newspapers have been the main historical sources used to follow these conflicts, and are expected to be widened in future investigations. Currently, social troubles are presented in a context of a period of economic growth and crisis. We start with the crisis of 1890, to conclude with the World War I crisis and the political changes that would come after 1916-1918

  1. Tanzanian farmers' knowledge and attitudes to GM biotechnology and the potential use of GM crops to provide improved levels of food security. A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Herron Caroline M

    2010-07-01

    Full Text Available Abstract Background Genetically Modified (GM crops have been championed as one possible method to improve food security and individual nutritional status in sub Saharan Africa. Understanding and acceptability of GM crop technology to farmers and consumers have not been assessed. We developed a qualitative research study involving farmers as both producers and consumers to gauge the understanding of GM crop technology, its acceptability, and identifying issues of concern. Methods Nineteen individual interviews (10 male and 9 female and five mixed gender focus group discussions with local farmers were conducted in 3 regions in Tanzania. Analysis took place concurrently with data collection. Following initial interviews, subsequent questions were adjusted based on emerging themes. Results Understanding, awareness and knowledge of GM crop technology and terminology and its potential risks and benefits was very poor in all regions. Receptivity to the potential use of GM crops was, however, high. Respondents focused on the potential benefits of GM crops rather than any potential longer term health risks. A number of factors, most significantly field trial data, would influence farmers' decisions regarding the introduction of GM crop varieties into their farming practice. Understanding of the potential improved health provision possible by changes in agricultural practice and food-related decision making, and the health benefits of a diet containing essential vitamins, minerals and micronutrients is also poor in these communities. Conclusion This study forms a basis from which further research work can be undertaken. It is important to continue to assess opinions and attitudes of farmers and consumers in sub Saharan Africa towards potential use of GM technologies whilst highlighting the importance of the relationship between agriculture, health and development. This will allow people in the region to make accurate, informed decisions about whether they

  2. The Controversy over GM Canola in Australia as an Ontological Politics

    OpenAIRE

    Rosemary Robins

    2012-01-01

    In this paper I examine the controversy over genetically modified canola (GM canola) in Australia as an ontological politics, drawing on recent work in Science and Technology Studies that extends actor-network theory and its commitment to the contingency of reality. I examine three different and overlapping performances of GM canola: as an agronomic object, a risk object and a market object. I focus on how each performance effects similarities and differences between GM and conventional canol...

  3. GM RICE COMMERCIALIZATION AND ITS IMPACT ON THE GLOBAL RICE ECONOMY

    OpenAIRE

    Durand-Morat, Alvaro; Chavez, Eddie; Wailes, Eric

    2015-01-01

    Genetically-modified (GM) rice is an important technology surrounded with controversy and uncertainty, hence it warrants more in-depth analysis. While GM rice is considered by its supporters as having promising potential, many still remain passionately against its use. This study assesses the impacts of GM rice commercialization on the global rice market. We use the Arkansas Global Rice Model (AGRM) and the RICEFLOW model to provide stochastic and dynamic analyses. Scenarios of adoption, diff...

  4. Social Impacts of GM Crops in Agriculture: A Systematic Literature Review

    OpenAIRE

    Klara Fischer; Elisabeth Ekener-Petersen; Lotta Rydhmer; Karin Edvardsson Björnberg

    2015-01-01

    It has recently been argued that the fragmented knowledge on the social impacts of genetically modified (GM) crops is contributing to the polarised debate on the matter. This paper addresses this issue by systematically reviewing 99 peer-reviewed journal articles published since 2004 on the social impacts of GM crops in agriculture; summarising current knowledge, and identifying research gaps. Economic impact studies currently dominate the literature and mainly report that GM crops provide ec...

  5. Lack of association between autism and anti-GM1 ganglioside antibody

    OpenAIRE

    2013-01-01

    Forty of 54 children with autism were reported to have an elevated antibody response to GM1 ganglioside that correlated with disease severity.1 Antiganglioside autoantibodies, especially those directed at GM1, are known to be associated with and play a pathogenic role in some immune-mediated peripheral neuropathies.2,3 The presumed link between autism and anti-GM1 antibodies, therefore, implies that testing may identify a sizable subset of patients who would benefit from immunomodulatory ther...

  6. FORMACIÓN, CRISIS Y REORIENTACIONES DE LA VITIVINICULTURA EN MENDOZA Y SAN JUAN, 1970-2000. APORTES PARA EL ESTUDIO DEL SECTOR EN LA ARGENTINA

    Directory of Open Access Journals (Sweden)

    Rodolfo Richard-Jorba

    2006-12-01

    Full Text Available Las actuales provincias de Mendoza y San Juan, localizadas en el árido centro-oeste argentino, llevan a cabo sus actividades económicas principales en grandes oasis de regadío, pequeñas porciones del territorio, en las cuales se concentra más del 95% de la población. A lo largo de su historia los productos de sus viñedos fueron dotándolas de una clara identidad hasta conformar lo que hoy conocemos como la gran Región Vitivinícola Argentina.

  7. Manuel Tolosa Latour (1857-1919 y Elisa Mendoza Tenorio (1856-1929: precursores de la protección a la infancia en España

    Directory of Open Access Journals (Sweden)

    Juan Félix Rodríguez Pérez

    2014-10-01

    La famosa actriz Elisa Mendoza Tenorio, esposa de Manuel Tolosa Latour, abandonó la escena teatral y se unió a la campaña de su marido. Estableció premios de higiene y fundó instituciones dedicadas a divulgar las normas higiénicas domésticas. Junto a Tolosa participó en la Sociedad Protectora de los Niños, él como secretario general y ella como integrante destacada de la Junta de Damas de la institución benéfica.

  8. Strategies for energetic and environmental sustainability in cities with dry climates. Comparative assessment for updating the Urban and Building Code for the City of Mendoza, Argentina.

    OpenAIRE

    Carlos Rosa; Mariela Arboit

    2015-01-01

    Se presentan los resultados de un estudio dirigido a determinar las consecuencias energético ambientales de la implementación de un proyecto de reformas al Código Urbano y de Edificación preparado por la Municipalidad de la ciudad de Mendoza (Argentina). El objetivo principal de la reforma al código ha sido densificar el tejido urbano, que permitiría mejorar la eficacia funcional, controlando la expansión urbana periférica. Después de una evaluación de la propuesta municipal (PM), se concluyó...

  9. LA PARTICIPACIÓN DE LAS MUJERES EN LA REVOLUCIÓN MEXICANA: JUANA BELÉN GUTIÉRREZ DE MENDOZA (1875-1942)

    OpenAIRE

    Ana Lau Jaiven

    2005-01-01

    Este artículo constituye una biografía de una revolucionaria y las etapas por las cuales transita su pensamiento. Juana B. Gutiérrez de Mendoza nacida en el estado de Durango, participó destacadamente en la historia de las mujeres en México debido a su oposición al régimen dictatorial de Porfirio Díaz. Se dedicó al magisterio y al periodismo como muchas mujeres de su tiempo. Atacó furiosamente a la religión y pugnó por la educación para las mujeres.

  10. Panamericanismo femenino y protestantismo en México a través de la vida de la profesora Adelia Palacios Mendoza

    OpenAIRE

    Lau Jaiven, Ana; Rodríguez,Roxana

    2014-01-01

    El siguiente artículo explora el panamericanismo y el protestantismo desde la actuación femenina de una mujer metodista, maestra y científica: Adelia Palacios Mendoza. La importancia de estudiar la participación de esta mujer en el ámbito público, educativo y político radica en que Palacios transgredió el deber ser femenino de su época. A finales del siglo XIX y principios del XX, periodo en que Adelia sobresalió, el orden de género imperante recluía a las mujeres al espacio do...

  11. Mapa bioclimático para las travesías de Mendoza (Argentina) basado en la fenología foliar

    OpenAIRE

    González Loyarte, María Margarita; Menenti, Massimo; Diblasi, Ángela

    2009-01-01

    El objetivo fue generar un mapa bioclimático de la llanura de Mendoza que reflejara las diferencias climáticas expresadas por la actividad de la vegetación (fenología foliar) a escala regional. Se partió de la imagen digital del índice bioclimático de aridez P/ETP, generada en una etapa anterior a partir de una serie temporal de imágenes de índice verde (IVDN), y se recodificó en clases bioclimáticas. Se evaluó en...

  12. Evidencias de la zona de contacto entre los terrenos de Precordillera y Pie de Palo, Provincias de San Juan y Mendoza

    Directory of Open Access Journals (Sweden)

    Maximiliano García Torrejón

    2011-12-01

    Full Text Available Se realizó un estudio gravimétrico en la región norte de la cuenca Cuyana, entre las provincias de San Juan y Mendoza. Mediante relaciones de gradientes gravimétricos tales como señal analítica, Tilt y fase del Tilt, se observó un marcado gradiente, que fue interpretado como un cambio lateral de litologías, que coincidiría con el área de una probable paleosutura del margen proto-andino, que separa en el terreno compuesto de Cuyania, al terreno de Precordillera con el terreno de Pie de Palo.

  13. Constitución y actividades de la Mesa Provincial de Educación Ambiental en la provincia de Mendoza, Argentina.

    OpenAIRE

    Gabriela Diaz Isenrath; T Bilbao; Cristian Barbosa; Susana Lagos Silnik; Nora Marlia; Silvia Musso; Oscar Ongay Ugarteche; Mirta Zarate; Elba Alicia Pescetti de Cristaldo; Mauricio Bucheri; Flora Bertolotti

    2015-01-01

    La Educación Ambiental como actividad interdisciplinaria e interinstitucional, requiere de la planificación estratégica participativa, que permita la concreción de esfuerzos que suelen realizarse de manera aislada. Se expone el proceso llevado a cabo para la constitución de la Mesa de Educación Ambiental en la provincia de Mendoza, Argentina. A partir de la discusión sobre la problemática local del Cambio Climático y los requerimientos de  medidas de adaptación, se propone el espacio en el añ...

  14. La zona de alteración Arroyo La Chilca-Zanjón del Buitre, bloque de San Rafael, Mendoza The Arroyo La Chilca-Zanjón del Buitre alteration zone, San Rafael Massif, Mendoza

    Directory of Open Access Journals (Sweden)

    Nora Rubinstein

    2012-06-01

    Full Text Available La zona de alteración Arroyo La Chilca-Zanjón del Buitre está ubicada en el bloque de San Rafael (35°24'8" S; 68°19'25,8" O, Mendoza. Estudios previos definieron preliminarmente que corresponde a un sistema de tipo pórfro cuprífero vinculado genéticamente al magmatismo gondwánico. Esta área de alteración se desarrolla en una secuencia compuesta por brechas ignimbríticas e ignimbritas traquiandesíticas con intercalaciones de areniscas tobáceas y coladas andesíticas a las que intruyen cuerpos subvolcánicos andesíticos y traquiandesítico-dacíticos. La litología de la secuencia volcánica así como sus características geoquímicas confirman su correlación con la sección inferior del ciclo magmático Choiyoi (Pérmico inferior. El área de alteración presenta una zona potásica con una asociación compuesta por feldespato potásico-cuarzo-magnetita. A ésta se superpone alteración fílica con una asociación de cuarzo-muscovita-pirita-(rutilo acompañada por venillas de cuarzo-pirita. Por último se reconoce una carbonatización tardía. En las proximidades de la zona de alteración aforan vetillas con mineralización de pirita-calcopirita-galena-esfalerita en ganga de cuarzo. La geoquímica de metales indica moderadas anomalías de Ag y Au y pequeñas anomalías de Cu, Mo, Pb y Zn. El análisis estadístico permite definir la existencia de un pulso mineralizante de Cu-Mo y un segundo pulso de Mo reconocido solamente en Zanjón del Buitre. Asimismo se definen dos pulsos de Zn, uno de los cuales estaría genéticamente vinculado al Cu.The Arroyo La Chilca-Zanjón del Buitre alteration zone is located in the San Rafael Massif (35°24'8" S; 68°19'25,8" W, Mendoza. Previous works defined preliminary this deposit as a porphyry copper system genetically linked to the gondwanan magmatism. This alteration zone is hosted by a sequence composed of ignimbritic breccias and ignimbrites of trachyandesitic composition with interbedded

  15. Oncoides tipo Osagia en la Formación La Manga (Oxfordiano y su significado paleoecológico, arroyo La Vaina, Mendoza Osagids-types oncoids from La Manga Formation and their paleoecological significance, La Vaina Creek, Mendoza

    Directory of Open Access Journals (Sweden)

    R.M. Palma

    2007-11-01

    Full Text Available Oncoides microbianos fueron encontrados en calizas del Oxfordiano de la Formación La Manga en la sección del Arroyo La Vaina, provincia de Mendoza. Los oncoides se presentan en packstones, floatstones-rudstones o dispersos en wackestones. Presentan formas elípticas, ameboidales y esféricas. Se reconocieron diferentes tipos de oncoides de acuerdo a las características de sus envolturas: (1 laminaciones micríticas, (2 laminaciones grumosas, y (3 laminaciones con organismos incrustantes. Sus núcleos están representados por fragmentos de moluscos, equinoideos, peloides e intraclastos. La envoltura sigue la forma del núcleo en la zona interna de la corteza. Sin embargo, en las zonas externas, la laminación contiene organismos incrustantes dominados por nubeculáridos y serpúlidos. Algunos oncoides, especialmente las formas ameboidales y elípticas, están caracterizados por múltiples núcleos, representados por oncoides pequeños. Los oncoides aparecen conjuntamente con bivalvos, equinodermos, foraminíferos y serpúlidos. La fauna indica condiciones someras, tranquilas, y la excelente preservación de los equinodermos sugiere mínimo transporte antes del enterramiento. Los oncoides crecieron en un ambiente marino normal, en el sector submareal, de aguas someras, con agitación leve a moderada. El limitado rolido en el crecimiento de los oncoides probablemente fue acompañado por corrientes intermitentes que reorientaron los oncoides paralelos a la estratificación. La laminación discontinua con organismos incrustantes refleja períodos de no agitación y litificación que facilitaron el crecimiento de organismos incrustantes sobre oncoides estáticos durante un período de baja tasa de sedimentación. La depositación de calizas con oncoides ocurrió durante la somerización del intervalo carbonático, asociada con la emersión, exposición subaérea y desarrollo de un paleokarst, como consecuencia de fluctuaciones relativas del nivel

  16. Petrografía y geoquímica de las rocas gondwánicas del proyecto minero Don Sixto, Mendoza Petrography and geochemistry of the gondwanic rock units from Don Sixto mining project, Mendoza

    Directory of Open Access Journals (Sweden)

    Ana Cecilia Mugas Lobos

    2010-11-01

    Full Text Available El proyecto minero Don Sixto es un depósito epitermal de Au-Ag de baja sulfuración ubicado al sureste de la provincia de Mendoza; el recurso aurífero de este depósito es próximo a las 900.000 onzas. La mineralización en el área se encuentra principalmente diseminada y está alojada mayormente en volcanitas y piroclastitas riolíticas de la Formación Choique Mahuida y diques riolíticos del Grupo El Portillo, ambos representantes de la sección superior del Grupo Choiyoi. Los datos obtenidos por el relevamiento geológico y los estudios petrográficos realizados en las volcanitas-piroclastitas del área de estudio, permiten indicar que la Formación Choique Mahuida está representada por riolitas, intercaladas con mantos ignimbríticos y niveles aislados de depósitos lenticulares piroclásticos. Por su parte, los diques riolíticos del Grupo El Portillo, de rumbo general noroeste-sureste y norte-sur, están probablemente vinculados a la evolución de zonas de falla de carácter regional. La geoquímica de estas riolitas gondwánicas, de acuerdo a la distribución de sus elementos traza y tierras raras, indica que están genéticamente vinculadas entre sí y pertenecerían a una suite cosanguínea proveniente de magmas diferenciados más evolucionados que los conocidos hasta la fecha para rocas de la sección superior del Grupo Choiyoi. Las características geoquímicas de estos magmas concuerdan además con los datos conocidos para rocas equivalentes fuera del área de estudio, en base a los cuales se asigna la sección superior del Grupo a un ambiente geotectónico transicional entre uno de arco volcánico y uno de intraplaca.Don Sixto mining project is a low sulphidation epithermal Au-Ag ore deposit located at the southeast of Mendoza province; the gold resource of the deposit is close to 900.000 ounces. In the study area, the mineralization is mainly disseminated and it is hosted by rhyolitic volcanic and pyroclastic sequences of the

  17. Distribución espacio-temporal de larvas de Chironomidae (Diptera en un arroyo andino (Uspallata, Mendoza, Argentina Spatial and temporal distribution of larvae of Chironomidae (Diptera in an Andean stream (Uspallata, Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Erica E. Scheibler

    2008-12-01

    Full Text Available Se realizó un estudio sobre la composición larval de la familia Chironomidae en un arroyo andino en la localidad de Uspallata (Mendoza, Argentina. Se realizaron muestreos estacionales durante un ciclo anual completo (2001/2002 en tres sitios, siguiendo un gradiente altitudinal. Se midieron variables físico-químicas en campo y laboratorio. La relación entre presencia y abundancia de quironómidos y parámetros ambientales se exploró mediante un análisis de Correspondencia Canónica. Se identificaron siete géneros pertenecientes a cuatro subfamilias: Chironominae, Orthocladiinae, Podonominae y Tanypodinae. Orthocladiinae fue la subfamilia que tuvo mayor riqueza genérica (Cricotopus van der Wulp, Onconeura Andersen & Saether y Parametriocnemus Goetghebuer, densidad y frecuencia de aparición a nivel estacional y espacial. Podonominae (Podonomus Philippi y Podonomopsis Brundin se halló únicamente en SA mientras que Chironominae (Polypedilum Kieffer estuvo presente en UD. Tanypodinae (Pentaneura Philippi se encontró en los tres sitios de muestreo aunque con una densidad menor. Se detectó incremento de la conductividad y temperatura del agua, y disminución del tamaño del sustrato desde SA a UD, lo que coincide con la desaparición de Podonomus y Podonomopsis y la aparición de Polypedilum hacia UD. De este estudio se concluye que el sistema presenta baja riqueza genérica comparada con otros sistemas montañosos de Argentina.A study was conducted on the larval composition of the family Chironomidae in an Andean stream in Uspallata locality (Mendoza, Argentina. Seasonal samplings were performed over a full annual cycle (2001/2002 at three sites, along an altitudinal gradient. Physical and chemical variables were measured in both the field and the laboratory. Relationship between presence and abundance of chironomids and environmental parameters was explored using a Canonical Correspondence analysis. Seven genera were identified

  18. Darwin's observation in South America: what did he find at agua de la zorra, Mendoza province? Las observaciones de Darwin en Sudamérica: ¿Qué encontró en Agua de la Zorra, provincia de Mendoza?

    Directory of Open Access Journals (Sweden)

    Stella Poma

    2009-04-01

    Full Text Available Scarcely 23 km from Uspallata, along the track of the old national highway 7, lies the district of Agua de la Zorra, in Mendoza province in western Argentina. Charles Darwin visited the area during his South American journeys in the 19th century and discovered a geological sequence that contained a paleoflora never described before. The flora includes an important number of species, particularly what is considered a small conifer forest with many silicified trunks still in life position. Darwin described and interpreted the sequence as sedimentary; his records show a very detailed level of observation. He also wondered about the processes that would cause the burial of the paleoflora, which he considered had happened in a marine sedimentary environment. In the modern geological framework and after a detailed study of the rocks containing the trunks, it is now interpreted that the conifer forest was buried by pyroclastic flows. Darwin accurately described the fine volcanic materials as an essential part of the deposit, but the key of the enigma about the origin of the deposits and the burial of the forest is the identification of the pyroclastic flow features; these were unknown process at the time of Darwin´s observations and interpretation.A escasos 23 km de Uspallata, a lo largo de la antigua ruta nacional 7, se encuentra la localidad de Agua de la Zorra en la provincia de Mendoza al oeste de Argentina. La región fue explorada por Charles Darwin durante su viaje por Sudamérica en el siglo XIX. Allí descubrió una secuencia geológica conteniendo una paleoflora que no había sido descripta hasta entonces. La flora incluye un importante número de especies y particularmente, un pequeño bosque de coníferas, los que se encuentran silicificados, y en posición de vida. Darwin describió e interpretó la secuencia como sedimentaria; sus notas y descripciones muestran un alto nivel de detalle en las observaciones. Darwin además se cuestion

  19. State modernization and economic regulation in the provinces winemakers. Mendoza, 1936-1946 Modernización estatal y regulación económica en provincias vitivinicultoras. Mendoza, 1936-1946

    Directory of Open Access Journals (Sweden)

    María Silvia Ospital

    2009-01-01

    Full Text Available The policies implemented in the country to overcome the consequences of the crisis of 1930 were measures to regulate production and trade, in the case of agricultural activities and industries. The entity created to handle the winemaking was Junta Reguladora de Vinos, which began operations after 1935. At the same time that they put into execution the provisions adopted by this national institution, the provincial authorities in the producing region arbitrated various practices designed to offset the sharper edges of the crisis and to reposition the agricultural industry at local and national market. In the province of Mendoza provincial authorities prescribed, starting in 1936, some regulations aimed at modernizing the state apparatus in an attempt to achieve greater efficiency in the implementation of regulatory policies and making the machinery of government to the demands of the new stage. The creation of a office specifically dedicated to the production of statistics and economic research under the provincial Ministry of Finance was the most important measure in this regard, while other provisions were trying to find in contemporary tourism development of a complementary alternative traditional winesLas políticas implementadas en el país para superar las consecuencias de la crisis de 1930 se manifestaron, en el caso de las actividades agrarias y agroindustriales, en medidas de regulación de la producción y el comercio. La entidad creada para ocuparse de la vitivinicultura fue la Junta Reguladora de Vinos que comenzó a operar a partir de 1935. Al mismo tiempo que se ponían en ejecución las disposiciones emanadas de ese organismo nacional, las autoridades provinciales de la región productora arbitraban diversas prácticas destinadas a paliar las aristas más agudas de la crisis y a reposicionar a la agroindustria en el ámbito local y el mercado nacional. En la provincia de Mendoza las autoridades provinciales instrumentaron, a partir

  20. Control estructural en la distribución de las mineralizaciones de uranio del ciclo Choiyoi, bloque de San Rafael, Mendoza Structural control on the distribution of uranium mineralizations of the Choiyoi cycle, San Rafael Massif, Mendoza

    Directory of Open Access Journals (Sweden)

    María S. Japas

    2008-06-01

    Full Text Available Las mineralizaciones más importantes del distrito uranífero Sierra Pintada (Bloque de San Rafael, Mendoza se asocian a las rocas pertenecientes al ciclo magmático Choiyoi. En la sección inferior de este ciclo predominan los yacimientos alojados en areniscas de origen epiclástico. En la sección superior, en cambio, se encuentran pequeñas mineralizaciones vetiformes de escasa importancia económica. Durante el emplazamiento y la acumulación de estas volcanitas y sedimentitas pérmicas prevalecieron dos regímenes de esfuerzo diferentes: transpresional (fase orogénica San Rafael y transtensional (etapa postorogénica, los cuales condicionaron los sistemas mineralizantes. Mediante un estudio de fábrica deformacional se evaluó el grado de control ejercido por las estructuras sobre la distribución de las mineralizaciones de uranio durante estas dos etapas de deformación. De esta forma, se intenta aportar nuevos conocimientos sobre la génesis de estos depósitos en la provincia magmática Choiyoi y generar nuevas guías de exploración. A través de este análisis se pudieron definir tres órdenes de magnitud en el control estructural sobre los depósitos asociados al ciclo Choiyoi inferior, cuyo desarrollo fue condicionado por la fábrica de la fase orogénica sanrafaélica. En el caso de las mineralizaciones alojadas en rocas de la sección superior del ciclo Choiyoi, el campo transtensional post-sanrafaélico ejerció un control, directo o indirecto, durante el proceso mineralizante.The main mineralizations of the Sierra Pintada uranium district, San Rafael Massif, Mendoza, are associated with the Choiyoi volcanic province. In the lower section of this magmatic cycle uranium deposits hosted by epiclastic sandstones are predominant. In the upper section, small vein-type deposits of low economic significance are found instead. During the emplacement of these Permian volcanic and sedimentary sequences two different stress regimes, which

  1. Inserciones laborales tempranas: Los jóvenes trabajadores agrícolas en el Valle de Uco, Mendoza, Argentina Early labor markets incorporations: Agricultural young workers in the Uco Valley, Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Gabriel I Bober

    2011-06-01

    Full Text Available Este artículo presenta las diferentes formas de inserción laboral de trabajadores jóvenes en el Valle de Uco, en la provincia de Mendoza. Durante las últimas décadas, el Valle de Uco basó su patrón de desarrollo agrícola en un modelo intensivo y empresarial de sus tres principales cultivos: los viñedos, los frutales y las hortalizas. En la actualidad, atraviesa un proceso de profunda reconversión productiva, orientada mayoritariamente hacia el mercado externo, que entre otras consecuencias pasó a modificar el funcionamiento del mercado de trabajo local. En este artículo, se contemplan las diferentes situaciones que llevan al ingreso laboral de los jóvenes en este contexto, según el momento etáreo que atraviesen. Se analiza la relación que este proceso guarda con el tamaño y la estructura de las familias y la situación socio-económica del hogar al que pertenecen. También, se examina el vínculo entre las características de los hogares y la forma de inserción de los jóvenes en el mercado de trabajo, de acuerdo al tipo de ocupación en la que se desempeñan y al destino que le dan a sus ingresos. A partir de la realización de entrevistas en profundidad a trabajadores jóvenes y a informantes clave se pudo dar cuenta de las preferencias de los jóvenes con respecto a distintos tipos de trabajos, con particular énfasis en ciertos trabajos agrícolas y, también en relación a su futuro laboral.This article deals with the different ways that young workers in the Uco Valley, at the province of Mendoza, enter to the agrarian local labour market. During the last decadas, the Uco Valley based its pattern of agricultural development in an intensive business model of its three main crops: vineyards, orchards, and vegetables. Currently, it is undergoing a process of profound restructuring of production, mainly oriented towards foreign markets, which among different consequences has modified the functioning of local labour markets. In

  2. Analysis of the GM-CSF and GM-CSF/IL-3/IL-5 receptor common beta chain in a patient with pulmonary alveolar proteinosis

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Objective To investigate the expression of the granulocyte-macrophage colony-stimulating factor (GM-CSF) and GM-CSF/IL-3/IL-5 receptor common beta chain (βc receptor) in an adult patient with idiopathic pulmonary alveolar proteinosis (PAP), so as to demonstrate the possible association of the GM-CSF and βc receptor with the pathogenesis of human PAP. Methods The GM-CSF levels were measured with a commercial ELISA kit (sensitivity 5?pg/ml) and the βc receptor expression on the cell surface was detected by flow cytometry analysis. Reverse transcription-polymerase chain reaction (RT-PCR) analysis was employed to detect the expression of the GM-CSF mRNA and the βc receptor mRNA in peripheral blood mononuclear cells and alveolar macrophages. The entire coding regions of the GM-CSF cDNA and the βc receptor cDNA were sequenced by the Sanger dideoxy-mediated chain termination method to detect possible mutations. Results The patient with PAP failed to release the GM-CSF protein either from circulating mononuclear cells or from alveolar macrophages. The expression of the GM-CSF mRNA was normal after the stimulation of lipopolysaccharide, whereas a point mutation at position 382 of the GM-CSF cDNA from “T" to “C" was revealed by cDNA sequencing, which caused a change in amino acid 117 of the protein from isoleucine to threonine. The βc receptor expression on the cell surface was normal, and the βc receptor mRNA expression and the sequence of the entire coding region of the βc receptor were also normal. Conclusions The decreased GM-CSF production is associated with the pathogenesis of human PAP. A point mutation of the GM-CSF cDNA may contribute to the decreased GM-CSF production in our adult PAP patient. The mutation of the βc receptor in some of paediatric patients with PAP may not be a common problem in adult patients.

  3. 基于ARMA-GM-BP组合预测模型及应用

    Institute of Scientific and Technical Information of China (English)

    彭乃驰; 党婷

    2016-01-01

    文章介绍了ARMA、GM(1,1)模型并建立了ARMA-GM-BP组合预测模型;通过对中国2005~2013年(DP的预测和检验,表明该组合预测模型的拟合及测试效果比单独利用ARMA、GM(1,1)模型的效果有很大改善;最后运用ARMA-GM-BP组合预测模型,对中国2014年、2015年的GDP作出了预测.

  4. Functional properties and expression quantitative trait loci for phosphate transporter GmPT1 in soybean.

    Science.gov (United States)

    Song, Haina; Yin, Zhitong; Chao, Maoni; Ning, Lihua; Zhang, Dan; Yu, Deyue

    2014-02-01

    Phosphate (Pi) remobilization within a plant is critical for plant survival under Pi-limiting conditions. In this paper, a soybean Pi transporter gene, GmPT1, was characterized. A marked induction of GmPT1 transcript was observed in young leaves, mature leaves and lateral roots during long-term Pi starvation. Transgenic tobacco plants containing the GmPT1 gene were obtained using an Agrobacterium-mediated transformation system. Compared with wild-type plants, transgenic plants showed significant increases in phosphorus-use efficiency (PUE), photosystem II (PSII) function, total dry weight and seed weight under Pi-deficient conditions. GmPT1 expression levels and PUE were determined in a soybean recombinant inbred line population during a pot experiment that was conducted to measure chlorophyll fluorescence parameters, photosynthetic rate (PN ) and seed yield. Correlation analysis revealed that GmPT1 expression levels had significantly positive correlations with seed yield, PUE, PN and the quantum yield of PSII primary photochemistry (ΦPSII ). Expression quantitative trait loci (eQTL) mapping for GmPT1 revealed two eQTLs, one of which coincided with both the physical location of GmPT1 and a QTL associated with seed yield. These results suggest that GmPT1 plays a role in Pi remobilization, and it may be possible to improve soybean seed yields under Pi-limiting conditions by modulating GmPT1 expression levels.

  5. Long-chain GM1 gangliosides alter transmembrane domain registration through interdigitation

    DEFF Research Database (Denmark)

    Manna, Moutusi; Javanainen, Matti; Monne, Hector Martinez Seara

    2017-01-01

    together. Based on atomistic molecular dynamics simulations, we find that long-chain GM1 in the extracellular leaflet exhibits a strong tendency to protrude into the opposing bilayer leaflet. This interdigitation modulates the order in the cytosolic monolayer and thereby strengthens the interaction...... effect, the situation is altered with long-chain GM1. Here, the significant interdigitation induced by long-chain GM1 modulates the behavior in the cytosolic GM1-free leaflet, weakening and slowing down the membrane registration process. The observed physical interaction mechanism provides a possible...

  6. Ganglioside GM1 mimicry in Campylobacter strains from sporadic infections in the United States.

    Science.gov (United States)

    Nachamkin, I; Ung, H; Moran, A P; Yoo, D; Prendergast, M M; Nicholson, M A; Sheikh, K; Ho, T; Asbury, A K; McKhann, G M; Griffin, J W

    1999-05-01

    To determine whether GM1-like epitopes in Campylobacter species are specific to O serotypes associated with Guillain-Barré syndrome (GBS) or whether they are frequent among random Campylobacter isolates causing enteritis, 275 random enteritis-associated isolates of Campylobacter jejuni were analyzed. To determine whether GM1-like epitopes in Campylobacter species are specific to O serotypes associated with Guillan-Barre syndrome (GBS) or whether they are frequent among random Campylobacter isolates causing enteritis, 275 enteritis-associated isolates, randomly collected in the United States, were analyzed using a cholera-toxin binding assay [corrected]. Overall, 26.2% of the isolates were positive for the GM1-like epitope. Of the 36 different O serotypes in the sample, 21 (58.3%) contained no strains positive for GM1, whereas in 6 serotypes (16.7%), >50% of isolates were positive for GM1. GBS-associated serotypes were more likely to contain strains positive for GM1 than were non-GBS-associated serotypes (37.8% vs. 15.1%, P=.0116). The results suggest that humans are frequently exposed to strains exhibiting GM1-like mimicry and, while certain serotypes may be more likely to possess GM1-like epitopes, the presence of GM1-like epitopes on Campylobacter strains does not itself trigger GBS.

  7. GM crops in Ethiopia: a realistic way to increase agricultural performance?

    Science.gov (United States)

    Azadi, Hossein; Talsma, Nanda; Ho, Peter; Zarafshani, Kiumars

    2011-01-01

    Much has been published on the application of genetically modified (GM) crops in Africa, but agricultural performance has hardly been addressed. This paper discusses the main consequences of GM crops on agricultural performance in Ethiopia. Three main criteria of performance - productivity, equitability and sustainability - are evaluated in the context of the Ethiopian agricultural sector. We conclude that the application of GM crops can improve the agricultural productivity and sustainability, whereas equitability cannot be stimulated and might even exacerbate the gap between socioeconomic classes. Before introducing GM crops to Ethiopian agriculture, regulatory issues should be addressed, public research should be fostered, and more ex ante values and socioeconomic studies should be included.

  8. Construction and characterization of hGM-CSF-expressing K-562 cell line

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Objective The whole process of vaccine preparation is time-consuming and technically challenging. Here the hGM-CSF-engineered K-562 cell line was constructed to simplify tumor vaccine preparation process. Methods The eukaryocyte expressing plasmid pcDNA3.1/GM-CSF was first constructed and its accuracy was verified through sequencing. The pcDNA3.1/GM-CSF was transfected into COS-7 cells to verify GM-CSF expression and cytokine activity using TF-1 cell line. Then the plasmid was transfected into K-562 cell li...

  9. LG GM730e 智者的较量

    Institute of Scientific and Technical Information of China (English)

    Decision

    2009-01-01

    正当我们还在叹息拥有绚丽S-Class 3D界面的LG GC900e缺少一个智能操作系统支持时,驾驭着Windows Mobile 6.1的LG GM730就迈着矫健的步伐“轻轻的我来了”,携着S-Class的清新界面和胜过iPhone 3G的苗条身材,以及可升级Windows Mobile 6.5的微软承诺,当然还有好兄弟“中国联通”的坚强后盾。

  10. EDIBLE VACCINES FROM GM CROPS: CURRENT STATUS AND FUTURE SCOPE

    Directory of Open Access Journals (Sweden)

    Doshi V

    2013-06-01

    Full Text Available The idea of an edible vaccine is coming closer to reality as scientists have found a way to incorporate the protein gene with some antigen in some plants. The major hurdles in the path of an emerging vaccine technology are being overcome. In this context, genetically modified (GM plants are being investigated for the production of vaccines, antibodies and therapeutic proteins. The development of GM crops to produce drugs and vaccines has received considerable investment and is relatively well advanced. The myth surrounding edible vaccines and 'food as pill' is the difficulty to control their intake and distribution, particularly in developing countries where education levels and literacy may be low. However, this concept suffers from the fact that the potency of this class of vaccines and drugs remains unmasked to the majority of the population, which has to be publicized and campaigned in a scientific manner, to make it realistic and useful for the common man. Creating edible vaccines involves introduction of selected desired genes into plants and then inducing these altered plants to manufacture the encoded proteins. This process is known as "transformation," and the altered plants are called "transgenic plants." Like conventional subunit vaccines, edible vaccines are composed of antigenic proteins and are devoid of pathogenic genes. Thus, they have no way of establishing infection, assuring its safety, especially in immuno-compromised patients. Conventional subunit vaccines are expensive and technology-intensive, need purification, require refrigeration and produce poor mucosal response. In contrast, edible vaccines would enhance compliance, especially in children and because of oral administration, would eliminate the need for trained medical personnel. Their production is highly efficient and can be easily scaled up. If the technology is properly nurtured and given the right direction, it may usher into a new era where we will be asked to

  11. Ethical arguments relevant to the use of GM crops.

    Science.gov (United States)

    Weale, Albert

    2010-11-30

    The Nuffield Council on Bioethics (NCOB) has published two reports (1999 and 2004) on the social and ethical issues involved in the use of genetically modified crops. This presentation summarises their core ethical arguments. Five sets of ethical concerns have been raised about GM crops: potential harm to human health; potential damage to the environment; negative impact on traditional farming practice; excessive corporate dominance; and the 'unnaturalness' of the technology. The NCOB examined these claims in the light of the principle of general human welfare, the maintenance of human rights and the principle of justice. It concluded in relation to the issue of 'unnaturalness' that GM modification did not differ to such an extent from conventional breeding that it is in itself morally objectionable. In making an assessment of possible costs, benefits and risks, it was necessary to proceed on a case-by-case basis. However, the potential to bring about significant benefits in developing countries (improved nutrition, enhanced pest resistance, increased yields and new products) meant that there was an ethical obligation to explore these potential benefits responsibly, to contribute to the reduction of poverty, and improve food security and profitable agriculture in developing countries. NCOB held that these conclusions were consistent with any practical precautionary approach. In particular, in applying a precautionary approach the risks associated with the status quo need to be considered, as well as any risks inherent in the technology. These ethical requirements have implications for the governance of the technology, in particular mechanisms for enabling small-scale farmers to express their preferences for traits selected by plant breeders and mechanisms for the diffusion of risk-based evaluations.

  12. Dental status and dental treatment demands in preschoolers from urban and underprivileged urban areas in Mendoza city, Argentina.

    Science.gov (United States)

    Fernández, Claudia N; Squassi, Aldo; Bordoni, Noemí

    2015-04-01

    The aim of this study was to establish the association between dental status and demand for dental care in preschoolers at urban and underprivileged urban schools in the city of Mendoza. Dental status was diagnosed in a purposive sample of preschoolers at urban schools (Group U: n = 148) and underprivileged urban schools (Group UnU: n = 155) in Greater Mendoza city, by determining the following indicators: (a) caries-free children (%), and (b) dmft/DMFT and its discriminated components, including active non-cavitated enamel caries. The characteristics of demand for care were determined using an ad hoc structured questionnaire. The following were determined: frequency distributions and confidence intervals for categorical variables, measures of central tendency and dispersion, tests for differences in means (Student's t test), association (chi squared) and correlation among variables (Pearson's r), at a significance level p<0.05. Comparison of dental status variables between groups showed significantly higher values in group UnU for: d+D tooth (ẋ = 5.4} 3.8; t = 2.887; p = 0.004); dmft+DMFT (ẋ = 5.7}4.1; t = 0.466; p = 0.020); d+D surface (ẋ = 7.62} 6.2; t = 0.956; p = 0.014); f+F surface (ẋ = 0.12}4.5; t = 2.71; p = 0.007) and percentage of caries-free children (x2= 25.377; p= 0.018). The following trends were found in this group: higher demand on the government subsystem, fewer visits to the dentist (x2 = 7.02, p = 0.008) and greater difficulty in getting appointments (x2 = 19.91, pẋ0.001). Frequency of visits was associated to the severity of dental status (x2 = 19.412; pẋ0.001), but no correlation was found between frequency of visits during the past year and dmft+DMFT (Pearson's r coefficient = 0.091; p = 0.0426) Group U showed preferential demand for the private or "obra social" (trade union managed health insurance) systems (x2 = 78.85 p = 0.00) and there was no statistically significant association between visits to the dentist and dmft

  13. The bright optical flash from GRB 060117

    CERN Document Server

    Jel'inek, M; Kubánek, P; Hudec, R; Nekola, M; Grygar, J; Castro-Tirado, A J; Gorosabel, J; Hrabovsk'y, M; Mandat, D; Nosek, D; Palatka, M; Pandey, S B; Pech, M; Schovanek, P; De Postigo, A U; Vítek, S; Jel\\'inek, Martin; Prouza, Michael; Kub\\'anek, Petr; Hudec, Ren\\'e; Nekola, Martin; R}\\'idk\\'y, Jan {; Grygar, Ji{r}\\'i; Castro-Tirado, Alberto J.; Gorosabel, Javier; Hrabovsk\\'y, Miroslav; Mand\\'at, Du{s}an; Nosek, Dalibor; Palatka, Miroslav; Pandey, Shashi B.; Pech, Miroslav; Schov\\'anek, Petr; S}m\\'ida, Radom\\'ir {; Postigo, Antonio de Ugarte; V\\'itek, Stanislav

    2006-01-01

    We present a discovery and observation of an extraordinarily bright prompt optical emission of the GRB 060117 obtained by a wide-field camera atop the robotic telescope FRAM of the Pierre Auger Observatory from 2 to 10 minutes after the GRB. We found rapid average temporal flux decay of alpha = -1.7 +- 0.1 and a peak brightness R = 10.1 mag. Later observations by other instruments set a strong limit on the optical and radio transient fluxes, unveiling an unexpectedly rapid further decay. We present an interpretation featuring a relatively steep electron-distribution parameter p ~ 3.0 and providing a straightforward solution for the overall fast decay of this optical transient as a transition between reverse and forward shock.

  14. Emittance measurement of high-brightness microbeams

    Energy Technology Data Exchange (ETDEWEB)

    Ishizuka, Hiroshi; Nakahara, Yuriko (Fukuoka Inst. of Tech. (Japan)); Kawasaki, Sunao; Musyoki, S.; Shimizu, Hiroshi; Watanabe, Akihiko; Shiho, Makoto

    1994-09-01

    Arrays of microtriodes have recently become available due to the development of microfabricated field-emission electron sources. Computer simulation has shown that the brightness of beams emitted by them is significantly higher than that of the common microbeams, and possible application of the accelerated beam to free electron lasers has been discussed. Experimentation on beam generation has started, but methods for diagnosing the beam have not yet been established. Difficulty is predicted, because of the high brightness, in applying the conventional methods of emittance measurement. In this paper we propose a new method that determines the emittance without using apertures. The cross section of a converging beam is elongated by a quadrupole lens, and parameters of the emittance ellipse are obtained from the beam size on a screen when changing either the strength or the axial position of the quadrupole lens. (author).

  15. Modular Zero Energy. BrightBuilt Home

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, Robb [Steven Winter Associates, Inc., Norwalk, CT (United States); Butterfield, Karla [Steven Winter Associates, Inc., Norwalk, CT (United States)

    2016-03-01

    With funding from the Building America Program, part of the U.S. Department of Energy Building Technologies Office, the Consortium for Advanced Residential Buildings (CARB) worked with BrightBuilt Home (BBH) to evaluate and optimize building systems. CARB’s work focused on a home built by Black Bros. Builders in Lincolnville, Maine (International Energy Conservation Code Climate Zone 6). As with most BBH projects to date, modular boxes were built by Keiser Homes in Oxford, Maine.

  16. Extreme Ultraviolet Explorer Bright Source List

    Science.gov (United States)

    Malina, Roger F.; Marshall, Herman L.; Antia, Behram; Christian, Carol A.; Dobson, Carl A.; Finley, David S.; Fruscione, Antonella; Girouard, Forrest R.; Hawkins, Isabel; Jelinsky, Patrick

    1994-01-01

    Initial results from the analysis of the Extreme Ultraviolet Explorer (EUVE) all-sky survey (58-740 A) and deep survey (67-364 A) are presented through the EUVE Bright Source List (BSL). The BSL contains 356 confirmed extreme ultraviolet (EUV) point sources with supporting information, including positions, observed EUV count rates, and the identification of possible optical counterparts. One-hundred twenty-six sources have been detected longward of 200 A.

  17. Municipio, identidad cultural y comunidades indígenas. El caso huarpe en el noreste de Mendoza

    Directory of Open Access Journals (Sweden)

    Leticia Saldi

    2013-06-01

    Full Text Available En el presente artículo analizamos cómo funcionarios de la Municipalidad de Lavalle representan e interpelan a las comunidades indígenas huarpe situadas en el área no irrigada del noreste de Mendoza, área situada en el departamento de Lavalle. Éste se encuentra dividido socioterritorialmente en dos espacios. Uno irrigado, caracterizado como área de progreso, de producción agrícola y de herencia europea y el otro no irrigado, representado como área de atraso, de producción ganadera y de herencia precolonial. A partir de un análisis etnográfico, analizamos cómo el municipio gestiona local y cotidianamente la diversidad étnica, cultural, económica y política. Concluimos que las formas con que los funcionarios interpelan a las comunidades indígenas y a sus integrantes son en base a un doble movimiento, uno de reconocimiento explícito y el otro de individualización, invisibilización y deslegitimación hacia las mismas. Al invisibilizar a las comunidades como sujetos colectivos, funcionarios municipales intentan dar una identidad común que incorpore a los espacios irrigados y no irrigados y a sus poblaciones como pertenecientes a un mismo territorio, el departamental, a la vez que mantenga la jerarquización entre ambos. Al realizar este movimiento, el municipio se erige como el unificador y contenedor de ambos espacios y de los distintos grupos socio-étnicos que los integran.

  18. Evaluation of summer thermal conditions and the environmental efficiency of different urban square designs in Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Susana Stocco

    2015-03-01

    Full Text Available El objetivo de este trabajo es evaluar las consecuencias de las decisiones de diseño sobre el comportamiento térmico y la eficiencia ambiental de las plazas de la ciudad de Mendoza. A tal fin se seleccionaron tres casos de estudio, donde se evaluó el comportamiento de distintas estructuras presentes en las plazas. Para ello se desarrollaron mediciones de temperatura del aire mediante sensores fijos, durante un periodo de 40 días en la estación verano de 2012, los sensores fueron ubicados en las diferentes estructuras (bosque, prado y centro de la plaza y en su entorno urbano, siguiendo un eje en sentido norte-sur. Además se determinó el valor del factor de visión de cielo (SVF y la digitalización hemisférica de la trayectoria solar para todos los puntos evaluados. Los resultados ponen de manifiesto la necesidad de reflexionar y revisar las estructuras de plazas existentes, en cuanto a sus esquemas de diseño, dado que el esquema tradicional que plantea una distribución de espacios en forma simétrica, parece no ser el que combina en forma más eficiente las distintas variables involucradas en el comportamiento térmico de la plaza: materialidad, distribución de la vegetación y exposición solar. Además se observa que a menor densidad edilicia del entorno urbano en el cual se inserta la plaza, sus condiciones térmicas y su eficiencia ambiental pueden mejorarse, casi con independencia de otros factores, mediante un diseño apropiado del espacio.

  19. Detection of Slope Instabilities Along the National Road 7, Mendoza Province, Argentina, Using Multi-Temporal InSAR

    Science.gov (United States)

    Michoud, Clément; Derron, Marc-Henri; Baumann, Valérie; Jaboyedoff, Michel; Rune Lauknes, Tom

    2013-04-01

    About 2'230 vehicles per day pass through the National Road 7 that link Buenos Aires to Santiago de Chile, crossing Andes Cordillera. This extremely important corridor, being the most important land pass between Argentina and Chile, is exposed to numerous natural hazards, such as snow avalanches, rockfalls and debris flows and remains closed by natural hazards several days per year. This goal of this study is to perform a regional mapping of geohazard susceptibilities along the Road 7 corridor, as started by Baumann et al. (2005), using modern remote sensing and numerical approaches with field checking. The area of interest is located in the Mendoza Province, between the villages Potrerillos and Las Cuevas near the Chilean border. The diversity of soil and rock conditions, the active geomorphological processes associated to post-glacial decompression, seasonal freeze and thaw and severe storms along the road corridor, increase the risk to natural hazard. With the support of the European Space Agency (ESA Category-1 Project 7154), we have in this study processed a large number of ERS and Envisat ASAR scenes, covering the period from 1995 to 2000. We applied both the small-baseline (SB) and the persistent scatterer (PSI) multi-temporal interferometric SAR (InSAR) techniques. The study area contains sparse vegetation, and the SB InSAR method is therefore well suited to map the area containing mainly distributed scatterers. Furthermore, PSI algorithms are also used for comparison for selected landslides in the inventory. Both approaches show a relatively good coherence within mountain areas, which is a good point for the landslide detections along the road. Indeed, the authors identified several large slope instabilities even active scree deposits. This inventory is finally compared with field observations and with existing susceptibility maps regarding snow avalanches, debris-flows and rockfalls. The final objective of this project is to develop a risk strategy that

  20. Quaternary volcanic-sedimentary sequences and evolution of the Llancanelo Lake region (Southern Mendoza, Western Argentina) evidenced from geoelectric methods

    Science.gov (United States)

    de la Vega, Matias; Lopez, Ernesto; Osella, Ana; Rovere, Elizabeth I.; Violante, Roberto A.

    2012-12-01

    Llancanelo Lake region (Southern Mendoza Province, Western Argentina) is a key area for investigating the regional evolution of a tectonic basin affected by intense arc- and back-arc volcanism. However, the lack of enough outcrops makes it difficult to perform such reconstructions. In order to solve this problem, and with the aim of depicting the subsurface stratigraphy, 22 geoelectric surveys reaching more than 100 m depth were performed. The applied methodology, that combined geoelectrical measurements and field observations, is a continuation of previous works carried out in the region, and allowed for the first time to establish a near-surface stratigraphy that records the last evolutive stages of the lake. The studied region is mainly composed of Quaternary volcanic and sedimentary sequences. Four units were recognized on the basis of the geoelectrical differences (resistivity signal) supported by field observations where they crop out. Two of them have very high resistivity and are composed of basaltic lava flows, hence indicating the volcanic influence in the region. The other two have very low resistivity and correspond to sedimentary deposits, being the uppermost one composed of lacustrine sediments. The units were named according to the well-known stratigraphic scheme valid for the region. The studied stratigraphic sequence encompasses the time-span from the Pliocene to the present, and its interpretation allowed to establish the main evolutive stages, characterized by a complex interaction among tectonic, volcanic and climatic factors. The damming of the lake by basaltic flows and the consequent reduction of the lake's extension at times of intensive volcanic activity is one of the most significant events in its evolution.

  1. First Late Triassic Record of a Paleoentomofauna from South America(Malargüe Basin,Mendoza Province,Argentina)

    Institute of Scientific and Technical Information of China (English)

    Carsten BRAUCKMANN; Oscar F.GALLEGO; Norbert HAUSCHKE; Rafael G.MARTINS-NETO; Elke GROENING; Jan-M.ILGER; María B.LARA

    2010-01-01

    Late Middle Triassic to early Late Triassic insects from Argentina have been previously described from the Bermejo and Cuyana Basins where they have been recovered from the Ischichuca-Los Rastros and Potrerillos-Cacheuta Formations,respectively.The insect fauna discussed herein was collected during field studies in 1986/1987 from the Llantenes section(Norian to Rhaetian? Late Triassic),which is situated in the Malargtie Basin in southern Mendoza province.The insect remains were found in the upper part of the Llantenes section(Llantenes Formation),which is built up of two coarsening-upwards cycles reflecting a deltaic progradation of a fluvial into a lacustrine environment(lower part),succeeded by repeated progradations into a floodplaindominated environment(upper part; with finds of insects,conchostracans,fish remains,plant fragments,and drifted logs).The new finds represent the youngest Triassic insect records described from Argentina and even from South America in its entirety.There is only one contemporaneous fossil assemblage in Gondwana:in the Clarence/Moreton Basin(Aberdare Conglomerate; Late Norian)in Australia.The new Triassic insects include an impression of an isolated Mecopterida-like wing(Mendozachorista volkheimeri gen.et sp.nov.;Mendozachoristidae fam.nov.),coleopteran elytra of the Permosynidae(Ademosyne rosenfeldi sp.nov.and Ademosyne llantenesensis sp.nov.)and other isolated body fragments.This new Late Triassic entomofauna from Argentina is of considerable importance in the reconstruction of the biotic recovery of continental environments in Gondwana after the catastrophic mass extinction at the P/T boundary.

  2. On the origin of facular brightness

    CERN Document Server

    Kostik, R

    2016-01-01

    This paper studies the dependence of the CaIIH line core brightness on the strength and inclination of photospheric magnetic field, and on the parameters of convective and wave motions in a facular region at the solar disc center. We use three simultaneous datasets obtained at the German Vacuum Tower Telescope (Observatorio del Teide, Tenerife): (1) spectra of BaII 4554 A line registered with the instrument TESOS to measure the variations of intensity and velocity through the photosphere up to the temperature minimum; (2) spectropolarimetric data in FeI 1.56 $\\mu$m lines (registered with the instrument TIP II) to measure photospheric magnetic fields; (3) filtergrams in CaIIH that give information about brightness fluctuations in the chromosphere. The results show that the CaIIH brightness in the facula strongly depends on the power of waves with periods in the 5-min range, that propagate upwards, and also on the phase shift between velocity oscillations at the bottom photosphere and around the temperature min...

  3. The Bright SHARC Survey The Cluster Catalog

    CERN Document Server

    Romer, A K; Holden, B P; Ulmer, M P; Pildis, R A; Merrelli, A J; Adami, C; Burke, D J; Collins, C A; Metevier, A J; Kron, Richard G; Commons, K

    1999-01-01

    We present the Bright SHARC (Serendipitous High-Redshift Archival ROSAT Cluster) Survey, which is an objective search for serendipitously detected extended X-ray sources in 460 deep ROSAT PSPC pointings. The Bright SHARC Survey covers an area of 178.6 sq.deg and has yielded 374 extended sources. We discuss the X-ray data reduction, the candidate selection and present results from our on-going optical follow-up campaign. The optical follow-up concentrates on the brightest 94 of the 374 extended sources and is now 97% complete. We have identified thirty-seven clusters of galaxies, for which we present redshifts and luminosities. The clusters span a redshift range of 0.0696Bright SHARC clusters have not been listed in any previously ...

  4. Brightness illusion in the guppy (Poecilia reticulata).

    Science.gov (United States)

    Agrillo, Christian; Miletto Petrazzini, Maria Elena; Bisazza, Angelo

    2016-02-01

    A long-standing debate surrounds the issue of whether human and nonhuman species share similar perceptual mechanisms. One experimental strategy to compare visual perception of vertebrates consists in assessing how animals react in the presence of visual illusions. To date, this methodological approach has been widely used with mammals and birds, while few studies have been reported in distantly related species, such as fish. In the present study we investigated whether fish perceive the brightness illusion, a well-known illusion occurring when 2 objects, identical in physical features, appear to be different in brightness. Twelve guppies (Poecilia reticulata) were initially trained to discriminate which rectangle was darker or lighter between 2 otherwise identical rectangles. Three different conditions were set up: neutral condition between rectangle and background (same background used for both darker and lighter rectangle); congruent condition (darker rectangle in a darker background and lighter rectangle in a lighter background); and incongruent condition (darker rectangle in a lighter background and lighter rectangle in a darker background). After reaching the learning criterion, guppies were presented with the illusory pattern: 2 identical rectangles inserted in 2 different backgrounds. Guppies previously trained to select the darker rectangle showed a significant choice of the rectangle that appears to be darker by human observers (and vice versa). The human-like performance exhibited in the presence of the illusory pattern suggests the existence of similar perceptual mechanisms between humans and fish to elaborate the brightness of objects.

  5. GM allotypes in Native Americans: evidence for three distinct migrations across the Bering land bridge.

    Science.gov (United States)

    Williams, R C; Steinberg, A G; Gershowitz, H; Bennett, P H; Knowler, W C; Pettitt, D J; Butler, W; Baird, R; Dowda-Rea, L; Burch, T A

    1985-01-01

    We report the results of typings, for immunoglobulin G allotypes, of 5392 Native Americans from ten samples, the typings having been performed over the last 20 years. Four cultural groups are represented: the Pimans-Pima and Papago; the Puebloans-Zuni and Hopi; the Pai-Walapai; and the Athabascans-Apache and Navajo. The haplotype Gm1;21 has the highest frequency in each population while Gm1,2;21 is polymorphic in all except the Hopi. The Mongoloid marker Gm1;11,13 is found primarily in the Athabascans. The Caucasian haplotype Gm3;5,11,13 is found at polymorphic frequencies in several of the populations but its frequency is very low or absent among nonadmixed individuals. Although Nei's standard genetic distance analysis demonstrates genetic similarity at the Gm and Km loci, the heterogeneity that does exist is consistent both with what is known about the prehistory of Native Americans and traditional cultural categories. When the current Gm distributions are analyzed with respect to the three-migration hypothesis, there are three distinct Gm distributions for the postulated migrants: Gm1;21 and Gm1,2;21 for the Paleo-Indians 16,000 to 40,000 years ago; Gm1;21, Gm1,2;21, and Gm1;11,13 for the second wave of Na-Dene hunters 12,000 to 14,000 years ago; and Gm1;21 and Gm1;11,13 for the Eskimo-Aleut migration 9,000 years ago. The Pimans, Puebloans, and the Pai are descendents of the Paleo-Indians while the Apache and Navajo are the contemporary populations related to the Na-Dene. Finally, the Gm distribution in Amerindians is found to be consistent with a hypothesis of one migration of Paleo-Indians to South American, while the most likely homeland for the three ancestral populations is found to be in northeastern Asia.

  6. 14-3-3 proteins act as scaffolds for GmMYB62 and GmMYB176 and regulate their intracellular localization in soybean

    OpenAIRE

    2012-01-01

    Isoflavonoids are plant natural compounds predominantly found in leguminous plant. They play important functions in both nitrogen fixation and stress resistance. Many clinical studies have linked dietary intake of isoflavonoids to human health benefits. Binding of 14-3-3 proteins to GmMYB176, an isoflavonoid regulator, modulates expression of key isoflavonoids gene expression and its biosynthesis. We have recently demonstrated that the interaction of 14-3-3 proteins with GmMYB176 regulates nu...

  7. Sustainability of current GM crop cultivation : Review of people, planet, profit effects of agricultural production of GM crops, based on the cases of soybean, maize, and cotton

    OpenAIRE

    2011-01-01

    This report adresses the question whether the cultivation of genetically modified (GM) crops abroad for import in the Netherlands, as compared to the cultivation of their conventional (non-GM) counterparts, is in line with Dutch policy and societal aims striving after more sustainable forms of agriculture worldwide and the utilization of the benefits offered by biotechnology in a responsible manner. Three crops were selected as case study objects: sybean, maize and cotton. The sustainability ...

  8. Vida y muerte de doña Melchora Lemos, empresaria vitivinícola y terciaria de la Orden de Predicadores (Mendoza, Reino de Chile, 1691-1741

    Directory of Open Access Journals (Sweden)

    Lacoste, Pablo

    2006-08-01

    Full Text Available This paper studies the life and death of doña Melchora Lemos, «pulpera», miller and wine maker in Mendoza, in Chile’s Kingdom. She was the only woman who owned a «pulperia» in the province; she built the only mill of the city; and she leaded one of better winery of Mendoza. Her life and death developed under catholic church influence. The sources of the paper are unpublished documents taken from the historical Archives in Mendoza (Argentine and Santiago (Chile.

    El artículo examina la historia de vida y muerte de doña Melchora Lemos, singular empresaria del siglo XVIII. Ella era la única mujer que poseía una pulpería; levantó el entonces único molino harinero de la ciudad; y administró la bodega más moderna de la región desde el punto de vista de la tecnología. Estos hechos se produjeron en el contexto de una intensa vida religiosa como terciaria de la orden de Santo Domingo. El estudio se ha realizado a través de fuentes originales inéditas del Archivo Nacional de Chile y el Archivo Histórico de Mendoza.

  9. El problema de los robos: de los temores de la élite a las prácticas de subsistencia de los sectores subalternos. Mendoza (Río de la Plata, 1820-1831

    Directory of Open Access Journals (Sweden)

    Molina, Eugenia

    2014-04-01

    Full Text Available This essay focuses on a specific study of thefts that occurred in the jurisdiction of Mendoza at the time of the formation of the provincial state. To do this, we will analyze judicial cases and government documents preserved in the Historical Archive of Mendoza. The aim of the study is to determine if the fears of the local elite, in the face of what they interpreted as growing post-revolutionary social conflict, were borne out by the information given in the sources; furthermore, we also aim to detect on which offenses against property they prioritized surveillance and punishment.En este trabajo nos centramos en un estudio específico de los robos ocurridos en la jurisdicción de Mendoza en el momento de conformación del estado provincial. Para ello analizaremos expedientes judiciales y documentos gubernamentales conservados en el Archivo Histórico de Mendoza. El objetivo del estudio apunta a determinar si los temores de la élite local, ante lo que ella interpretaba como una creciente conflictividad social pos revolucionaria, se correspondieron con lo planteado en las fuentes; no obstante, también buscamos detectar sobre qué atentados contra la propiedad focalizaron la vigilancia y punición.

  10. Comparative Proteomic Analysis of Two Varieties of Genetically Modified (GM) Embrapa 5.1 Common Bean (Phaseolus vulgaris L.) and Their Non-GM Counterparts.

    Science.gov (United States)

    Balsamo, Geisi M; Valentim-Neto, Pedro A; Mello, Carla S; Arisi, Ana C M

    2015-12-01

    The genetically modified (GM) common bean event Embrapa 5.1 was commercially approved in Brazil in 2011; it is resistant to golden mosaic virus infection. In the present work grain proteome profiles of two Embrapa 5.1 common bean varieties, Pérola and Pontal, and their non-GM counterparts were compared by two-dimensional gel electrophoresis (2-DE) followed by mass spectrometry (MS). Analyses detected 23 spots differentially accumulated between GM Pérola and non-GM Pérola and 21 spots between GM Pontal and non-GM Pontal, although they were not the same proteins in Pérola and Pontal varieties, indicating that the variability observed may not be due to the genetic transformation. Among them, eight proteins were identified in Pérola varieties, and four proteins were identified in Pontal. Moreover, we applied principal component analysis (PCA) on 2-DE data, and variation between varieties was explained in the first two principal components. This work provides a first 2-DE-MS/MS-based analysis of Embrapa 5.1 common bean grains.

  11. LA PROFUNDIZACIÓN DE LA RACIONALIDAD INSTRUMENTAL COMO ESTRATEGIA DE LOS PODEROSOS FRENTE AL CAMBIO AMBIENTAL GLOBAL EN MENDOZA – ARGENTINA

    Directory of Open Access Journals (Sweden)

    Jorge Daniel Ivars

    2012-12-01

    Full Text Available En el presente artículo nos proponemos describir la racionalidad subyacente a las estrategias de adaptación al cambio ambiental global de los agentes poderosos de la vitivinicultura en Mendoza, Argentina. En términos estrictamente físicos, el Cambio Ambiental Global se presenta como un aumento de las temperaturas promedio a nivel global, las repercusiones de este cambio serán diferentes según sea la zona geográfica del planeta que se considere. En el oasis norte de la Provincia de Mendoza se espera una reducción en los caudales del Río que lo alimenta. Frente a esta situación, los actores poderosos de la vitivinicultura mendocina han optado por estrategias de adaptación tendientes a profundizar la racionalidad instrumental, característica de estos grupos, para hacer frente al cambio ambiental global: obtener aguas en mayor cantidad y calidad a través del traslado de sus explotaciones a zonas de montaña ubicadas aguas arriba del río  y búsqueda de mercados internacionales, entre otras.

  12. La colección de armas de Íñigo López de Mendoza, V duque del Infantado

    Directory of Open Access Journals (Sweden)

    González Ramos, Roberto

    2014-12-01

    Full Text Available Don Íñigo López de Mendoza, 5th Duke of the Infantado, was one of the major arms collectors of his day. This essay deals with the content of his armoury, as well as the reasons and mechanism of its creation in the 16th Century. Further more, the text focuses on the uses of the arms of Don Iñigo and with the degree of knowledge Infantado had of what today we understand as modern collectionism.Don Íñigo López de Mendoza, V duque del Infantado, fue uno de los coleccionistas de armas más importantes de la Europa del Siglo XVI. Este artículo se centra en el estudio de su armería analizando su contenido y explicándolo para entender los mecanismos y las razones de su creación, así como de su uso y adecuación a lo que hoy entendemos como coleccionismo moderno.

  13. Resistencias al orden formalizado por la Constitución de Mendoza de 1854 en el ámbito de la campaña

    Directory of Open Access Journals (Sweden)

    Inés Sanjurjo de Driollet

    2004-01-01

    Full Text Available The work analyzes the effective application of the principles of the modern constitutionalism in Mendoza after it was formalized the liberal order by means of the Constitution of 1854. The investigation tries to quarrel if in the period of this constitution life (1854-1895, nevertheless the bigger complexity of the state mechanisms and the politics of strengthening the legal authority on the territory, there were spaces that escaped to this power, or practices resistant to the principles in vogue. The work has put on particular attention to the rural localities, which for the distances or small accessibility, is estimated they were less inclined to the changes and less exposed to the state control.El trabajo analiza la efectiva aplicación de los principios del moderno constitucionalismo en Mendoza luego de formalizado el orden liberal mediante la carta magna provincial de 1854. Trata de averiguar, si en el período de su vigencia (1854-1895, no obstante el proceso de complejización del aparato estatal y la política de afianzamiento de su potestad sobre el territorio, quedaron espacios que escaparon a ese poder, o se dieron prácticas resistentes a los principios en boga. Se ha puesto particular atención a las localidades de la campaña, que por las distancias o la poca accesibilidad, se estima eran poco proclives a los cambios y estaban menos expuestas al control estatal.

  14. Les variations récentes (1975-2000 de l’englacement dans le Massif de l’Aconcagua (Mendoza, Argentine

    Directory of Open Access Journals (Sweden)

    Julie Le Gall

    2008-03-01

    Full Text Available La région de Mendoza est particulièrement vulnérable au réchauffement climatique. Les glaciers du massif de l’Aconcagua ont amorcé un important retrait depuis la fin du Petit Âge de Glace. Or la disparition de ces glaciers risque d’entraîner une modification des régimes hydrologiques qui, jusqu’à présent, se caractérisaient par de hautes eaux estivales. Ce pic estival pourrait à l’avenir être atténué et remettre en cause les stratégies de gestion de la ressource en eau. Nous faisons ici le point sur les variations récentes de l’englacement et tentons de dessiner un scénario prospectif.Mendoza area is highly vulnerable to the global warming. The glaciers of the Aconcagua massif are currently shrinking, this trend of retreat began at the end of the Little Ice Age. The disappearance of glaciers may modify hydrological regimes. The discharge is currently at maximum during summer (related to glacier melt, but the peak discharge may occur during spring (related to snow melt in the next future. In this paper we synthesize the recent variations of the glaciers and propose a pattern of future variations.

  15. ALGUNAS CONCEPTUALIZACIONES Y ENFOQUES DOMINANTES EN LA GESTIÓN HÍDRICA DEL OASIS NORTE DE LA PROVINCIA DE MENDOZA, ARGENTINA

    Directory of Open Access Journals (Sweden)

    Virgínia Grosso

    2012-08-01

    Full Text Available  Mendoza, provincia árida del centro oeste de la República Argentina, ha vivenciado en los últimos tiempos la profundización del debate sobre la problemática de la escasez de agua. Este trabajo tiene por objetivo aproximarse a las respuestas de las siguientes preguntas: ¿qué factores han construido y construyen la denominada escasez hídrica en la provincia? ¿Se presenta de manera homogénea en todo el territorio mendocino? Para abordarlas, primeramente, se analizarán y correlacionarán los aportes teóricos de la nueva economía y cultura del agua y de la teoría y problación-recursos en torno a la noción de escasez. Y en segundo lugar, se identificarán las problemáticas hídricas (de apropiación, gestión y uso que se observan a lo largo de la cuenca del río Mendoza.

  16. Mineralización de talco asociada a los cuerpos ultramáficos de la Faja del Río de Las Tunas, Cordillera Frontal de Mendoza

    Directory of Open Access Journals (Sweden)

    Gargiulo, María Florencia

    2011-12-01

    Full Text Available Talc mineralization related to the ultramafic bodies of the Río de Las Tunas belt, Frontal Cordillera of Mendoza province. This contribution shows the main characteristics of the talc mineralization related to the Río de Las Tunas ultramafic bodies in the Salamanca Mining District, Frontal Cordillera of Mendoza province. According to the parageneses defined on the studied samples, three generations of talc were established: 1º crystallized in metaperidotites and related to the prograde stage of the regional metamorphism; 2º crystallized inreaction zones (mostly in the talc zone developed at the boundary between metaperidotites and their country-rocks.These reaction zones evidence a metasomatic process due to geochemical gradient between the ultramafic body and their country-rocks. This process was developed during the retrogression of the regional metamorphic cycle. 3º Talc present in shear-zones that cut across the ultramafic bodies. The extreme serpentinization of the ultramaficbodies is concentrated in shear-zones where the serpentine is subsequently replaced by talc ± carbonates related with a hydrothermal stage. Aqueous fluids relatively enriched in CO2 flowed through these shear-zones causing the cease of serpentine formation favoring the talc and/or carbonates. Mined talc deposits are those in shear zones and reaction zones. They are mostly industrial-, asbestine- or talcschist-type. The talc related to the hydrothermal stage can locally reach first and extra qualities.

  17. Estimation of the space density of low surface brightness galaxies

    NARCIS (Netherlands)

    Briggs, FH

    1997-01-01

    The space density of low surface brightness and tiny gas-rich dwarf galaxies are estimated for two recent catalogs: the Arecibo Survey of Northern Dwarf and Low Surface Brightness Galaxies and the Catalog of Low Surface Brightness Galaxies, List II. The goals are (1) to evaluate the additions to the

  18. Evolution of European GM-free standards: Reasoning of consumers and strategic adoption by companies

    NARCIS (Netherlands)

    Venus, T.J.; Wesseler, J.H.H.

    2015-01-01

    In this article, we discuss reasoning of consumers and strategic adoption behavior of producers and retailers with respect to genetically modified-free (GM-free) quality standards in Europe. We argue that there are three major reasons why a mandatory GM labeling scheme differs from a voluntary proce

  19. Consumer choice: Linking consumer intentions to actual purchase of GM labeled food products.

    Science.gov (United States)

    Sleenhoff, Susanne; Osseweijer, Patricia

    2013-01-01

    With a mandatory labeling scheme for GM food in Europe since 2004 measuring actual consumer choice in practice has become possible. Anticipating Europeans negative attitude toward GM food, the labeling was enforced to allow consumers to make an informed choice. We studied consumers actual purchase behavior of GM food products and compared this with their attitude and behavioral intention for buying GM food. We found that despite a majority of consumers voicing a negative attitude toward GM food over 50% of our European respondents stated that they did not actively avoid the purchase of GM food and 6% actually purchased one of the few available GM labeled food products in the period between September 2006 and October 2007. Our results imply that a voiced negative attitude of consumers in responses to questionnaires about their intentions is not a reliable guide for what they actually do in supermarkets. We conclude that the assumption of a negative attitude with regard to GM food is at least in part construed.

  20. Consumer choice: Linking consumer intentions to actual purchase of GM labeled food products

    NARCIS (Netherlands)

    Sleenhoff, S.; Osseweijer, P.

    2013-01-01

    With a mandatory labeling scheme for GM food in Europe since 2004 measuring actual consumer choice in practice has become possible. Anticipating Europeans negative attitude toward GM food, the labeling was enforced to allow consumers to make an informed choice. We studied consumers actual purchase b

  1. Does insect netting affect the containment of airborne pollen from (GM-) plants in greenhouses?

    NARCIS (Netherlands)

    van Hengstum, T.; Hooftman, D.A.P.; den Nijs, H.C.M.; van Tienderen, P.H.

    2012-01-01

    Greenhouses are a well-accepted containment strategy to grow and study genetically modified plants (GM) before release into the environment. Various containment levels are requested by national regulations to minimize GM pollen escape. We tested the amount of pollen escaping from a standard greenhou

  2. Biotech/GM crops in horticulture: plum cv. HoneySweet resistant to plum pox virus

    Science.gov (United States)

    Commercialization of Biotech crops started in 1995. By 2011, genetically modified (GM) crops were grown world-wide on 160 million ha. Only 114.507 ha of GM crops were grown in Europe, of that, 114.490 ha were Bt maize and 17 ha were potato for industrial starch production. Currently, developing c...

  3. Determination of dose rates in beta radiation fields using extrapolation chamber and GM counter

    DEFF Research Database (Denmark)

    Borg, J.; Christensen, P.

    1995-01-01

    of depth-dose profiles from different beta radiation fields with E(max) values down to 156 keV. Results are also presented from studies of GM counters for use as survey instruments for monitoring beta dose rates at the workplace. Advantages of GM counters are a simple measurement technique and high...

  4. Non-target effects of GM potato : an eco-metabolomics approach

    NARCIS (Netherlands)

    Plischke, Andreas

    2013-01-01

    In this thesis, patterns of variation in plant metabolomes and insect communities were described in GM and non-GM potato plants in both laboratory and field experiments. Differences between plant genotypes in insect abundances were small when compared to year-to-year differences, location effects an

  5. Arabidopsis KLU homologue GmCYP78A72 regulates seed size in soybean.

    Science.gov (United States)

    Zhao, Baotian; Dai, Aihua; Wei, Haichao; Yang, Suxin; Wang, Baoshan; Jiang, Ning; Feng, Xianzhong

    2016-01-01

    Soybean (Glycine max) is one of the most important crops in the world, and its yield is largely determined by grain weight and grain size. However, the genes that regulate soybean seed size have not been identified. CYP78A, which is highly conserved within terrestrial plants, regulates organ development. In Arabidopsis, AtCYP78A5/KLU has been shown to determine seed size. In the present study, soybean CYP78A72 (GmCYP78A72), one of the orthologs of KLU, was over-expressed in both Arabidopsis and soybean to examine its function in plant development. GmCYP78A72 heterologous expression in Arabidopsis resulted in enlarged sepals, petals, seeds and carpel. Over-expression of GmCYP78A72 in soybean resulted in increased pea size, which is an extremely desirable trait for enhancing productivity. Moreover, knock-down of GmCYP78A72 does not reduce grain size. However, silencing of GmCYP78A57, GmCYP78A70 and GmCYP78A72 genes in triplet reduces the seed size significantly indicating functional redundancy of these three GmCYP78A genes. In conclusion, we investigated the role of CYP78A in soybean seed regulation, and our strategy can be effectively used to engineer large seed traits in soybean varieties as well as other crops.

  6. The corporate shaping of GM crops as a technology for the poor

    NARCIS (Netherlands)

    Glover, D.

    2010-01-01

    Genetically modified (GM, transgenic) crops are often invoked in debates about poverty, hunger, and agricultural development. The framing of GM crops as a 'pro-poor' and environmentally sustainable technology was partly a creation of the biotechnology industry, but cannot be explained as merely a cy

  7. Spectroscopic Characterization of Intermolecular Interaction of Amyloid β Promoted on GM1 Micelles

    Directory of Open Access Journals (Sweden)

    Maho Yagi-Utsumi

    2011-01-01

    Full Text Available Clusters of GM1 gangliosides act as platforms for conformational transition of monomeric, unstructured amyloid β (Aβ to its toxic β-structured aggregates. We have previously shown that Aβ(1–40 accommodated on the hydrophobic/hydrophilic interface of lyso-GM1 or GM1 micelles assumes α-helical structures under ganglioside-excess conditions. For better understanding of the mechanisms underlying the α-to-β conformational transition of Aβ on GM1 clusters, we performed spectroscopic characterization of Aβ(1–40 titrated with GM1. It was revealed that the thioflavin T- (ThT- reactive β-structure is more populated in Aβ(1–40 under conditions where the Aβ(1–40 density on GM1 micelles is high. Under this circumstance, the C-terminal hydrophobic anchor Val39-Val40 shows two distinct conformational states that are reactive with ThT, while such Aβ species were not generated by smaller lyso-GM1 micelles. These findings suggest that GM1 clusters promote specific Aβ-Aβ interactions through their C-termini coupled with formation of the ThT-reactive β-structure depending on sizes and curvatures of the clusters.

  8. GM crops in Ethiopia : a realistic way to increase agricultural performance?

    NARCIS (Netherlands)

    Azadi, Hossein; Taisma, Nanda; Ho, Peter; Zarafshani, Kiumars

    2011-01-01

    Much has been published on the application of genetically modified (GM) crops in Africa, but agricultural performance has hardly been addressed. This paper discusses the main consequences of GM crops on agricultural performance in Ethiopia. Three main criteria of performance productivity, equitabili

  9. LONG-DISTANCE GM POLLEN MOVEMENT OF CREEPING BENTGRASS USING MODELED WIND TRAJECTORY ANALYSIS

    Science.gov (United States)

    The importance of understanding the role of atmospheric conditions in pollen dispersal has grown in recent years with increased field-testing of genetically modified (GM) crop plants. An atmospheric model was used to characterize wind trajectories at 10 m and 100 m above GM polle...

  10. Nanomolar cholera toxin inhibitors based on symmetrical pentavalent ganglioside GM1os-sym-corannulenes

    NARCIS (Netherlands)

    Mattarella, M.; Garcia-Hartjes, J.; Wennekes, T.; Zuilhof, H.; Siegel, J.S.

    2013-01-01

    Eight symmetric and pentavalent corannulene derivatives were functionalized with galactose and the ganglioside GM1-oligosaccharide (GM1os) via copper-catalyzed alkyne-azide cycloaddition (CuAAC) reactions. The compounds were evaluated for their ability to inhibit the binding of the pentavalent chole

  11. "It just goes against the grain." Public understandings of genetically modified (GM) food in the UK.

    Science.gov (United States)

    Shaw, Alison

    2002-07-01

    This paper reports on one aspect of qualitative research on public understandings of food risks, focusing on lay understandings of genetically modified (GM) food in the UK context. A range of theoretical, conceptual, and empirical literature on food, risk, and the public understanding of science are reviewed. The fieldwork methods are outlined and empirical data from a range of lay groups are presented. Major themes include: varying "technical" knowledge of science, the relationship between knowledge and acceptance of genetic modification, the uncertainty of scientific knowledge, genetic modification as inappropriate scientific intervention in "nature", the acceptability of animal and human applications of genetic modification, the appropriate boundaries of scientific innovation, the necessity for GM foods, the uncertainty of risks in GM food, fatalism about avoiding risks, and trust in "experts" to manage potential risks in GM food. Key discussion points relating to a sociological understanding of public attitudes to GM food are raised and some policy implications are highlighted.

  12. EVOLUTION OF EUROPEAN GM-FREE STANDARDS: REASONING OF CONSUMERS AND STRATEGIC ADOPTION BY COMPANIES

    Directory of Open Access Journals (Sweden)

    Thomas J. VENUS

    2015-11-01

    Full Text Available In this article, we discuss reasoning of consumers and strategic adoption behavior of producers and retailers with respect to genetically modified-free (GM-free quality standards in Europe. We argue that there are three major reasons why a mandatory GM labeling scheme differs from a voluntary process-based GM-free labeling scheme regarding the effect on consumer demand: (1 while both mandatory and voluntary labels signal that products containing, or produced with genetically modified organisms (GMOs are of lower quality, experiments show that the signaling effect is stronger in the case of mandatory labels; (2 some consumers care more about the effects of consuming GMOs directly (i.e., labeled GMO compared to consuming only products derived from GMOs (i.e., non-labeled GM-free; and (3 mandatory labeling shifts some of the labeling burden to the GM producer making the GM product relatively more expensive compared to the case of voluntary GM-free labeling. We discuss reasons why producers or retailers set or implement a voluntary GM-free production standard. To illustrate how the firm adoption theory can be extended, we use a real option game framework in a duopolistic setting and show that it can be beneficial to offer a GM-free product without labeling it. We show that this can be the case if investing without labeling works as a pre-investment or option to extend to reduce the investment cost of implementing a label in the case of an increase in demand. Finally, we provide a list of important events that have affected the evolution of the GM-free market in Europe.

  13. A Meta Analysis on Farm-Level Costs and Benefits of GM Crops

    Directory of Open Access Journals (Sweden)

    Nataliya Stupak

    2011-05-01

    Full Text Available This paper reviews the evidence on the socio-economic impacts of GM crops and analyzes whether there are patterns across space and time. To this end, we investigate the effect of GM crops on farm-level costs and benefits using global data from more than one decade of field trials and surveys. More specifically, we analyze the effects of GM-crops on crop yields, seed costs, pesticide costs, and management and labor costs and finally gross margins. Based on collected data from studies on Bt cotton and Bt maize, statistical analyses are conducted to estimate the effect of GM crop adoption on these parameters. Our results show that, compared to conventional crops, GM crops can lead to yield increases and can lead to reductions in the costs of pesticide application, whereas seed costs are usually substantially higher. Thus, the results presented here do support the contention that the adoption of GM crops leads on average to a higher economic performance, which is also underlined by the high adoption rates for GM crops in a number of countries. However, the kind and magnitude of benefits from GM crops are very heterogeneous between countries and regions, particularly due to differences in pest pressure and pest management practices. Countries with poor pest management practices benefited most from a reduction in yield losses, whereas other countries benefited from cost reductions. However, our study also reveals limitations for meta-analyses on farm-level costs and benefits of GM crops. In particular, published data are skewed towards some countries and the employed individual studies rely on different assumptions, purposes and methodologies (e.g., surveys and field trials. Furthermore, a summary of several (often short-term individual studies may not necessarily capture long-term effects of GM crop adoption.

  14. Análisis del campo de esfuerzos en una secuencia lacustre de Precordillera oriental, San Juan-Mendoza Analysis of the stress field in a lacustrine sequence of eastern Precordillera, San Juan-Mendoza

    Directory of Open Access Journals (Sweden)

    Laura P. Perucca

    2008-06-01

    Full Text Available En la quebrada del río Acequión, ubicada en el sur de la provincia de San Juan y norte de Mendoza (32º 10' S, en el centrooeste argentino, se efectuó el análisis de las fallas que afectan depósitos lacustres de edad holocena. Estas fallas se encuentran asociadas a estructuras de licuefacción y avalanchas de roca indicadoras de paleoterremotos, lo que permite extender el registro sísmico de la región hasta el Holoceno temprano. Al comparar el campo de esfuerzos regional actual (determinado por sismicidad instrumental, con el cálculo del mecanismo focal de los terremotos recientes ocurridos en la región con el campo de esfuerzos local, se observó que mientras el primero se caracteriza por la compresión, el campo local de la secuencia lacustre es extensional. Esto indicaría que aunque el esfuerzo regional actual es compresivo y de dirección NE-SO debido a la convergencia entre las placas de Nazca y Sudamérica, el antiguo lago adosado a las sierras de Pedernal y Los Pozos, está afectado por fallas normales, principalmente debido a esfuerzos locales distensivos originados por el reacomodamiento de estos depósitos durante el levantamiento de las zonas montañosas aledañas.An analysis of faults affecting Late Neogene lacustrine deposits was made in Acequión area, placed in the south of the province of San Juan. These faults are associated with liquefaction structures and rock avalanche deposits originated by paleoearthquakes, extending the earthquake records until the early Holocene in this region. By comparing the present regional stress field (determined by instrumental seismicity, with the focal mechanism analysis of recent earthquakes occurred in the region with the local stress field, it was observed that whereas the first one is characterized by compression, the local field on the lacustrine sequence is normal. The current regional stress field is compressive due to the subduction of Nazca plate under South America plate. The

  15. Flora y vegetación del valle superior del Rió Atuel (Mendoza-Argentina Flora and vegetation of the Upper Valley of the Atuel River (Mendoza-Argentina

    Directory of Open Access Journals (Sweden)

    Ernesto A Morici

    2010-06-01

    Full Text Available El valle superior del Río Atuel presenta variaciones altitudinales y topográficas, siendo un territorio de confluencia de elementos propios de las provincias fitogeográficas Andina, del Monte, de la estepa Patagónica y de la Payunia. En este trabajo se estudia su flora y vegetación, a través de censos florísticos siguiendo la metodología de Braun-Blanquet (1979. A partir de la matriz de especies por censos se determinó el espectro biológico ponderado y la diversidad florística. Además, se estimó la cobertura basal registrándose los porcentajes de vegetación, broza, suelo desnudo, roca y fragmentos de roca. El estudio se desarrolló en un área restringida a la vertiente norte del Río Atuel entre su intersección con la Ruta Nacional 40 y las inmediaciones de la Planta de Azufre. En los censos se registraron un total de 89 especies pertenecientes a 36 familias, siendo las más numerosas Asteraceae, Poaceae, Verbenaceae, Fabaceae y Solanaceae. El 96% de las especies son nativas y sólo el 4% exóticas. Se diferenciaron 15 comunidades: 12 matorrales, 1 pastizal, 1 herbazal y 1 estepa de cojines.In this study we present a description of the flora and vegetation of the upper valley of Rio Atuel, Mendoza Province. In this area, characteristic taxa fron the Andina, Monte, Payunia and Patagonia Phytogeographical Provinces overlap their ranges. Considering that Atuel river high valley shows relevant altitudinal and topographical variations and a confluence of typical components from Andina, Monte, Patagonia and Payunia phytogeographic provinces, we plained to study, flora and vegetation. Floristic censuses were performed according to Braun-Blanquet (1979 and the matrix at coverage species was used to obtain cover data, weighted biological spectrum and floristic diversity. Furthermore, basal cover was estimated and vegetation, litter, bare soil, stones and stone pieces were recorded. This research was developed in an area restricted to the

  16. Evolution of bulgeless low surface brightness galaxies

    Science.gov (United States)

    Shao, X.; Hammer, F.; Yang, Y. B.; Liang, Y. C.

    Based on the Sloan Digital Sky Survey DR 7, we investigate the environment, morphology, and stellar population of bulgeless low surface-brightness (LSB) galaxies in a volume-limited sample with redshift ranging from 0.024 to 0.04 and M r LSB galaxies have more young stars and are more metal-poor than regular LSB galaxies. These results suggest that the evolution of LSB galaxies may be driven by their dynamics, including mergers rather than by their large-scale environment.

  17. The radio properties of bright Seyfert galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Giuricin, G.; Mardirossian, F.; Mezzetti, M.; Bertotti, G. (Centro Interuniversitario Regionale per l' Astrofisica e la Cosmologia (Italy) Centre for Advanced Research in Space Optics (Italy))

    1990-03-01

    The radio properties of a sample of 69 bright spectroscopically selected Seyfert galaxies, which suffers from little bias toward Markarian galaxies with strong UV excess. At variance with most of the earlier results, generally based on galaxy samples which are strongly biased toward the inclusion of Markarian objects, there is no clear evidence of a significant difference in the major radio properties (radio power, radio-to-optical luminosity ratio, radio spectral index and radio size) of type 1 and type 2 Seyferts. The resulting observational scenario appears now to be more consistent than before with the idea that Seyfert 2 galaxies are simply Seyfert 1 obscured objects. 70 refs.

  18. Effects of GM-CSF, IL-3, and GM-CSF/IL-3 fusion protein on apoptosis of human myeloid leukemic cell line Tf-1 induced by irradiation

    Institute of Scientific and Technical Information of China (English)

    Su-rongYANG; LiWEN; Ying-qingLU; Qin-yanGONG; RongYU; Ming-huiYAO

    2004-01-01

    AIM: To observe the effects of three cytokines on the apoptosis of Tf-1 cells induced by γ irradiation and investigate the relationship between apoptosis and caspase-3 activity. METHODS: Different cytokines GM-CSF, IL-3 and GM-CS/IL-3 fusion protein were added into the irradiated Tf-1 cells. MTT assay, morphology, flow cytometry,and DNA fragmentation assay were used to observe the effects of cytokines on apoptosis. The caspase-3 activity was determined with a fluorocytometer. RESULTS: Irradiated Tf-1 cells showed typical morphological characteristic of apoptosis demonstrated by transmission electron microscopy and were accumulated in G0/G1 phase. In the groups treated with growth factors after irradiation, three cytokines significantly increased the viability rate, distinctly decreased the apoptosis rate and the proportion of DNA fragmentation. When Tf-1 cells were irradiated by γ irradiation, caspase-3 activity was increased at different time points. In comparison with the control group in which no growth factor was added after the cells were irradiated, the caspase-3 activity of irradiated Tf-1 cells was significantly inhibited by addition of the above cytokines. Thirty-six hours after irradiation, in the control group,GM-CSF, IL-3, GM-CSF and IL-3 in combination, and two GM-CSF/IL-3 fusion protein groups, the apoptosis ratewas 73 %, 11%, 15 %, 13 %, 12 %, and 13 %. The percent of fragmented DNA was 36 %, 19 %, 18 %, 14 %,13 %, and 14 %. The fluorescence intensity was 16923, 5529, 6581, 5322, 5426, and 5485. CONCLUSION:GM-CSF, IL-3, and GM-CSF/IL-3 fusion protein could protect Tf-1 cells from apoptosis induced by γ irradiation.After Tf-1 cells were irradiated, the caspase-3 activity was significantly increased but was dramatically decreased by the above cytokines. The remarkable inhibition of caspase-3 activity may be one of the mechanisms of these hematopoietic growth factors exerting their anti-apoptotic effects.

  19. TNF alpha acts in synergy with GM-CSF to induce proliferation of acute myeloid leukemia cells by up-regulating the GM-CSF receptor and GM-CSF gene expression.

    Science.gov (United States)

    Brailly, H; Pebusque, M J; Tabilio, A; Mannoni, P

    1993-10-01

    Acute myeloid leukemia (AML) cells are dependent for their survival and proliferation on hematopoietic growth factors. As tumor necrosis factor alpha (TNF alpha) can increase the proliferation of primary cultures of AML cells, we have investigated the effect of TNF alpha on the autocrine and/or paracrine growth control by one of the major AML growth factor, granulocyte-macrophage colony-stimulating factor (GM-CSF). First, a panel of AML cells were analysed with respect to their proliferative response to TNF alpha. We provide experimental evidence that TNF alpha induces both GM-CSF gene expression and up-regulation of high-affinity GM-CSF membrane receptor in TNF alpha-responsive cells. This effect is not restricted to the malignant phenotype, although it could account for the selective growth advantage of the leukemic clone over the normal cells upon TNF alpha stimulation.

  20. The role of the Fraunhofer lines in solar brightness variability

    CERN Document Server

    Shapiro, A I; Krivova, N A; Tagirov, R V; Schmutz, W K

    2015-01-01

    The solar brightness varies on timescales from minutes to decades. A clear identification of the physical processes behind such variations is needed for developing and improving physics-based models of solar brightness variability and reconstructing solar brightness in the past. This is, in turn, important for better understanding the solar-terrestrial and solar-stellar connections. We estimate the relative contributions of the continuum, molecular, and atomic lines to the solar brightness variations on different timescales. Our approach is based on the assumption that variability of the solar brightness on timescales greater than a day is driven by the evolution of the solar surface magnetic field. We calculated the solar brightness variations employing the solar disc area coverage of magnetic features deduced from the MDI/SOHO observations. The brightness contrasts of magnetic features relative to the quiet Sun were calculated with a non-LTE radiative transfer code as functions of disc position and waveleng...

  1. Helium compressor for GM and pulse-tube expanders

    Science.gov (United States)

    Longsworth, R. C.

    2002-05-01

    A new compressor system has been developed for cooling MRI magnets which has more displacement than the present compressor. By increasing the displacement from 2.9 L/s to 5.2 L/s at 60 Hz it is possible to provide more refrigeration at lower temperatures with both GM and Pulse-tube expanders. The 2.9 L/s compressor is a rolling piston type, which is cooled by water circulating through tubes bonded to the outside of the compressor shell. The 5.2 L/s compressor is a scroll type that is cooled by circulating oil to an external heat exchanger. One of the key features of the design is an oil removal system that enables the adsorber replacement interval to be increased to 5 years. A diagnostic module is incorporated in the control circuit to alert the user to an abnormal condition and show the reason for a shut down if it occurs. This paper describes essential design features and the extensive testing that has been done to characterize the compressor over a wide range of operating conditions including extremes that it might experience.

  2. Imaging the photoevaporating disk and radio jet of GM Aur

    CERN Document Server

    Macias, Enrique; Osorio, Mayra; Calvet, Nuria; Torrelles, Jose M; Gomez, Jose F; Espaillat, Catherine; Lizano, Susana; Rodriguez, Luis F; Carrasco-Gonzalez, Carlos; Zapata, Luis

    2016-01-01

    Photoevaporation is probably the main agent for gas dispersal during the last stages of protoplanetary disk evolution. However, the overall mass loss rate in the photoevaporative wind and its driving mechanism are still not well understood. Here we report multi-configuration Very Large Array observations at 0.7, 3, and 5 cm towards the transitional disk of GM Aur. Our radio continuum observations allow us to image and spatially resolve, for the first time, the three main components at work in this stage of the disk evolution: the disk of dust, the ionized radio jet perpendicular to it, and the photoevaporative wind arising from the disk. The mass loss rate inferred from the flux density of the radio jet is consistent with the ratio between ejection and accretion rates found in younger objects, suggesting that transitional disks can power collimated ejections of material apparently following the same physical mechanisms as much younger protostars. Our results indicate that extreme-UV (EUV) radiation is the mai...

  3. GM crops, the environment and sustainable food production.

    Science.gov (United States)

    Raven, Peter H

    2014-12-01

    Today, over 7.1 billion people rely on the earth's resources for sustenance, and nearly a billion people are malnourished, their minds and bodies unable to develop properly. Globally, population is expected to rise to more than 9 billion by 2050. Given the combined pressures of human population growth, the rapidly growing desire for increased levels of consumption, and the continued use of inappropriate technologies, it is not surprising that humans are driving organisms to extinction at an unprecedented rate. Many aspects of the sustainable functioning of the natural world are breaking down in the face of human-induced pressures including our individual and collective levels of consumption and our widespread and stubborn use of destructive technologies. Clearly, agriculture must undergo a redesign and be better and more effectively managed so as to contribute as well as possible to feeding people, while at the same time we strive to lessen the tragic loss of biodiversity and damage to all of its productive systems that the world is experiencing. For GM crops to be part of the solution, biosafety assessments should not be overly politically-driven or a burdensome impedance to delivering this technology broadly. Biosafety scientists and policy makers need to recognize the undeniable truth that inappropriate actions resulting in indecision also have negative consequences. It is no longer acceptable to delay the use of any strategy that is safe and will help us achieve the ability to feed the world's people.

  4. ESTRATEGIAS ALIMENTARIAS Y DE SUBSISTENCIA PREHISPÁNICA EN EL CENTRO-OESTE DE MENDOZA: CONSUMO Y DESCARTE EN EL SITIO ARQUEOLÓGICO AGUA AMARGA / Food and subsistence strategies in the prehispanic Mendoza Midwest: Consumption and discard at Agua Amarga

    Directory of Open Access Journals (Sweden)

    María José Ots

    2011-12-01

    Full Text Available Se presenta el análisis de un depósito de desechos asociados a la alimentación en Agua Amarga (departamento de Tupungato, en el Centro Oeste de la provincia de Mendoza. Agua Amarga es un sitio residencial de actividades múltiples ubicado en el piedemonte del Valle de Uco, a 1000 msnm. Los fechados obtenidos sobre cerámica y restos vegetales del contexto lo ubican en el período tardío y de dominación incaica regional. El propósito del trabajo es estudiar estrategias de procesamiento, consumo y descarte de alimentos que asimismo contribuyan a la discusión sobre las estrategias de subsistencia prehispánicas en el Norte y Centro de Mendoza. Se aplican métodos y técnicas específicos para la identificación y el análisis de los restos, y se proponen hipótesis alternativas sobre dicho contexto. Los materiales recuperados, la mayoría de ellos termoalterados y muy fragmentados, incluyen macrorrestos arqueobotánicos (principalmente Zea mays y Phaseulus vulgaris, restos óseos (algunos elementos identificados como Lama sp., fragmentos de distintos recipientes cerámicos y de artefactos de molienda.  Finalmente, se discuten prácticas asociadas con la alimentación y la subsistencia, con especial referencia a la producción y consumo de maíz en el área.   Palabras clave: alimentación, subsistencia, maíz, Mendoza   Abstract We present the study of a refuse deposit associated with feeding activities in the archaeological site Agua Amarga (Tupungato department, Middle West of Mendoza province. This is a residencial site of multiple activities located in the foothill in Valle de Uco, to 1000 masl. We dated ceramics and vegetal remains that locate the context in the late period and during regional inca domination. Our goal is to study strategies of processing, consumption and discarding of foods that also contribute in the discussion on the prehispanic strategies of subsistence in the North and Center of Mendoza province. In this paper

  5. Panchromatic Imaging of a Transitional Disk: The Disk of GM Aur in Optical and FUV Scattered Light

    CERN Document Server

    Hornbeck, Jeremy; Grady, Carol; Williger, G; Broan, A; Sitko, M; Wisniewski, J; Perrin, M; Lauroesch, J; Schneider, G; Apai, D; Brittain, S; Brown, J; Champnew, E; Hamaguchi, K; Henning, T; Lynch, D; Petre, R; Russell, R; Walter, F; Woodgate, B

    2016-01-01

    We have imaged GM Aur with HST, detected its disk in scattered light at 1400A and 1650A, and compared these with observations at 3300A, 5550A, 1.1 microns, and 1.6 microns. The scattered light increases at shorter wavelengths. The radial surface brightness profile at 3300A shows no evidence of the 24AU radius cavity that has been previously observed in sub-mm observations. Comparison with dust grain opacity models indicates the surface of the entire disk is populated with sub-micron grains. We have compiled an SED from 0.1 microns to 1 mm, and used it to constrain a model of the star+disk system that includes the sub-mm cavity using the Monte Carlo Radiative Transfer code by Barbara Whitney. The best-fit model image indicates that the cavity should be detectable in the F330W bandpass if the cavity has been cleared of both large and small dust grains, but we do not detect it. The lack of an observed cavity can be explained by the presence of sub-microns grains interior to the sub-mm cavity wall. We suggest one...

  6. La dinámica de la sustentabilidad fiscal en los municipios urbanos de la Provincia de Mendoza

    Directory of Open Access Journals (Sweden)

    Raúl Molina

    2016-11-01

    Full Text Available La finalidad del trabajo es revisar el comportamiento fiscal comparado de los departamentos urbanos que forman parte del “Gran Mendoza” (Capital, Guaymallén, Godoy Cruz y Las Heras, así como analizar distintos indicadores de sustentabilidad fiscal y su aplicación a la situación actual y futura de los mismos. A partir del análisis de la deuda pública consolidada y su relación con los resultados financieros de los respectivos municipios, se analizan las perspectivas de solvencia de cada uno de ellos, para determinar, en su caso, los esfuerzos fiscales necesarios para retomar la senda de la sustentabilidad. Sin duda, la efectividad de la política presupuestaria y tributaria, y el nivel del gasto público, repercuten claramente en los resultados de la gestión, pero hay también otros aspectos, como la selección de formas alternativas para financiar el gasto público y el manejo del endeudamiento, que impactan en los resultados financieros de los municipios. Clasificación JEL: H7.Palabras clave: Finanzas Públicas Intergubernamentales; Estados sub-nacionales; Solvencia fiscal; Sustentabilidad; Déficits. The dynamics of fiscal sustainability in the urban municipalities of the Province of MendozaAbstractThe purpose of this paper is to review the fiscal performance compared to urban municipalities of “Gran Mendoza” (Capital, Guaymallén, Godoy Cruz and Las Heras and to analyze different indicators of fiscal sustainability and its application to the current and future situation of them. From the analysis of the consolidated public debt and its relationship to the financial performance of the respective municipalities, the prospects solvency of each of them are analyzed to determine the necessary fiscal efforts to resume the path of sustainability. Certainly the effectiveness of budgetaryl and tax policy, and the level of public spending clearly affect the results of management, but there are also other aspects such as the selection

  7. Early Callovian ingression in southwestern Gondwana. Palaeoenvironmental evolution of the carbonate ramp (Calabozo Formation) in southwestern Mendoza, Neuquen basin, Argentina

    Science.gov (United States)

    Armella, Claudia; Cabaleri, Nora G.; Cagnoni, Mariana C.; Panarello, Héctor O.

    2013-08-01

    The carbonatic sequence of the Calabozo Formation (Lower Callovian) developed in southwestern Gondwana, within the northern area of the Neuquén basin, and is widespread in thin isolated outcrops in southwestern Mendoza province, Argentina. This paper describes the facies, microfacies and geochemical-isotopic analysis carried out in five studied localities, which allowed to define the paleoenvironmental conditions of a homoclinal shallow ramp model, highly influenced by sea level fluctuations, where outer, mid and inner ramp subenvironments were identified. The outer ramp subenvironment was only recognized in the south of the depocenter and is characterized by proximal outer ramp facies with shale levels and interbedded mudstone and packstone layers. The mid ramp subenvironment is formed by low energy facies (wackestone) affected by storms (packstones, grainstones and floatstones). The inner ramp subenvironment is the most predominant and is characterized by tidal flat facies (wackestones, packstones and grainstones) over which a complex of shoals (grainstones and packstones) dissected by tidal channels (packstone, grainstones and floatstones) developed. In the north area, protected environment facies were recorded (bioturbated wackestones and packstones). The vertical distribution of facies indicates that the paleoenvironmental evolution of the Calabozo Formation results from a highstand stage in the depocenter, culminating in a supratidal environment, with stromatolitic levels interbedded with anhydrite originated under restricted water circulation conditions due to a progressive isolation of the basin. δ13C and δ18O values of the carbonates of the Calabozo Formation suggest an isotopic signature influenced by local palaeoenvironmental parameters and diagenetic overprints. The δ13C and δ18O oscillations between the carbonates of the different studied sections are related with lateral facies variations within the carbonate ramp accompanied with dissimilar

  8. Radial patterns of bitumen dykes around Quaternary volcanoes, provinces of northern Neuquén and southernmost Mendoza, Argentina

    Science.gov (United States)

    Cobbold, Peter R.; Ruffet, Gilles; Leith, Leslie; Loseth, Helge; Rodrigues, Nuno; Leanza, Hector A.; Zanella, Alain

    2014-12-01

    Where the Neuquén Basin of Argentina abuts the Andes, hundreds of veins of solid hydrocarbon (bitumen) are visible at the surface. Many of these veins became mines, especially in the last century. By consensus, the bitumen has resulted from maturation of organic-rich shales, especially the Vaca Muerta Fm of Late Jurassic age, but also the Agrio Fm of Early Cretaceous age. To account for their maturation, recent authors have invoked regional subsidence, whereas early geologists invoked magmatic activity. During 12 field seasons (since 1998), we have tracked down the bitumen localities, mapped the veins and host rocks, sampled them, studied their compositions, and dated some of them. In the provinces of northern Neuquén and southernmost Mendoza, the bitumen veins are mostly sub-vertical dykes. They tend to be straight and continuous, crosscutting regional structures and strata of all ages, from Jurassic to Palaeocene. Most of the localities lie within 70 km of Tromen volcano, although four are along the Rio Colorado fault zone and another two are at the base of Auca Mahuida volcano. On both volcanic edifices, lavas are of late Pliocene to Pleistocene age. Although regionally many of the bitumen dykes tend to track the current direction of maximum horizontal tectonic stress (ENE), others do not. However, most of the dykes radiate outward from the volcanoes, especially Tromen. Thicknesses of dykes tend to be greatest close to Tromen and where the host rocks are the most resistant to fracturing. Many of the dykes occur in the exhumed hanging walls of deep thrusts, especially at the foot of Tromen. Here the bitumen is in places of high grade (impsonite), whereas further out it tends to be of medium grade (grahamite). A few bitumen dykes contain fragments of Vaca Muerta shale, so that we infer forceful expulsion of source rock. At Curacó Mine, some shale fragments contain bedding-parallel veins of fibrous calcite (beef) and these contain some bitumen, which is

  9. Spectral evolution of bright NS LMXBs

    CERN Document Server

    Paizis, A; Mainardi, L I; Titarchuk, L

    2010-01-01

    Theoretical and observational support suggests that the spectral evolution of neutron-star LMXBs, including transient hard X-ray tails, may be explained by the interplay between thermal and bulk motion Comptonization. In this framework, we developed a new model for the X-ray spectral fitting XSPEC package which takes into account the effects of both thermal and dynamical (i.e. bulk) Comptonization, CompTB. Using data from the INTEGRAL satellite, we tested our model on broad band spectra of a sample of persistently low magnetic field bright neutron star Low Mass X-ray Binaries, covering different spectral states. The case of the bright source GX 5-1 is presented here. Particular attention is given to the transient powerlaw-like hard X-ray (above 30 keV) tail that we interpret in the framework of the bulk motion Comptonization process, qualitatively describing the physical conditions of the environment in the innermost part of the system.

  10. Sublimation in bright spots on (1) Ceres.

    Science.gov (United States)

    Nathues, A; Hoffmann, M; Schaefer, M; Le Corre, L; Reddy, V; Platz, T; Cloutis, E A; Christensen, U; Kneissl, T; Li, J-Y; Mengel, K; Schmedemann, N; Schaefer, T; Russell, C T; Applin, D M; Buczkowski, D L; Izawa, M R M; Keller, H U; O'Brien, D P; Pieters, C M; Raymond, C A; Ripken, J; Schenk, P M; Schmidt, B E; Sierks, H; Sykes, M V; Thangjam, G S; Vincent, J-B

    2015-12-10

    The dwarf planet (1) Ceres, the largest object in the main asteroid belt with a mean diameter of about 950 kilometres, is located at a mean distance from the Sun of about 2.8 astronomical units (one astronomical unit is the Earth-Sun distance). Thermal evolution models suggest that it is a differentiated body with potential geological activity. Unlike on the icy satellites of Jupiter and Saturn, where tidal forces are responsible for spewing briny water into space, no tidal forces are acting on Ceres. In the absence of such forces, most objects in the main asteroid belt are expected to be geologically inert. The recent discovery of water vapour absorption near Ceres and previous detection of bound water and OH near and on Ceres (refs 5-7) have raised interest in the possible presence of surface ice. Here we report the presence of localized bright areas on Ceres from an orbiting imager. These unusual areas are consistent with hydrated magnesium sulfates mixed with dark background material, although other compositions are possible. Of particular interest is a bright pit on the floor of crater Occator that exhibits probable sublimation of water ice, producing haze clouds inside the crater that appear and disappear with a diurnal rhythm. Slow-moving condensed-ice or dust particles may explain this haze. We conclude that Ceres must have accreted material from beyond the 'snow line', which is the distance from the Sun at which water molecules condense.

  11. Internetwork chromospheric bright grains observed with IRIS

    CERN Document Server

    Martínez-Sykora, Juan; Carlsson, Mats; De Pontieu, Bart; Pereira, Tiago M D; Boerner, Paul; Hurlburt, Neal; Kleint, Lucia; Lemen, James; Tarbell, Ted D; Title, Alan; Wuelser, Jean-Pierre; Hansteen, Viggo H; Golub, Leon; McKillop, Sean; Reeves, Kathy K; Saar, Steven; Testa, Paola; Tian, Hui; Jaeggli, Sarah; Kankelborg, Charles

    2015-01-01

    The Interface Region Imaging Spectrograph (IRIS) reveals small-scale rapid brightenings in the form of bright grains all over coronal holes and the quiet sun. These bright grains are seen with the IRIS 1330 \\AA, 1400 \\AA\\ and 2796 \\AA\\ slit-jaw filters. We combine coordinated observations with IRIS and from the ground with the Swedish 1-m Solar Telescope (SST) which allows us to have chromospheric (Ca II 8542 \\AA, Ca II H 3968 \\AA, H\\alpha, and Mg II k 2796 \\AA), and transition region (C II 1334 \\AA, Si IV 1402) spectral imaging, and single-wavelength Stokes maps in Fe I 6302 \\AA at high spatial (0.33"), temporal and spectral resolution. We conclude that the IRIS slit-jaw grains are the counterpart of so-called acoustic grains, i.e., resulting from chromospheric acoustic waves in a non-magnetic environment. We compare slit-jaw images with spectra from the IRIS spectrograph. We conclude that the grain intensity in the 2796 \\AA\\ slit-jaw filter comes from both the Mg II k core and wings. The signal in the C II ...

  12. Coronal bright points associated with minifilament eruptions

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Junchao; Jiang, Yunchun; Yang, Jiayan; Bi, Yi; Li, Haidong [Yunnan Observatories, Chinese Academy of Sciences, Kunming 650011 (China); Yang, Bo; Yang, Dan, E-mail: hjcsolar@ynao.ac.cn [Also at Graduate School of Chinese Academy of Sciences, Beijing, China. (China)

    2014-12-01

    Coronal bright points (CBPs) are small-scale, long-lived coronal brightenings that always correspond to photospheric network magnetic features of opposite polarity. In this paper, we subjectively adopt 30 CBPs in a coronal hole to study their eruptive behavior using data from the Atmospheric Imaging Assembly (AIA) and the Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamics Observatory. About one-quarter to one-third of the CBPs in the coronal hole go through one or more minifilament eruption(s) (MFE(s)) throughout their lifetimes. The MFEs occur in temporal association with the brightness maxima of CBPs and possibly result from the convergence and cancellation of underlying magnetic dipoles. Two examples of CBPs with MFEs are analyzed in detail, where minifilaments appear as dark features of a cool channel that divide the CBPs along the neutral lines of the dipoles beneath. The MFEs show the typical rising movements of filaments and mass ejections with brightenings at CBPs, similar to large-scale filament eruptions. Via differential emission measure analysis, it is found that CBPs are heated dramatically by their MFEs and the ejected plasmas in the MFEs have average temperatures close to the pre-eruption BP plasmas and electron densities typically near 10{sup 9} cm{sup –3}. These new observational results indicate that CBPs are more complex in dynamical evolution and magnetic structure than previously thought.

  13. Mechanical electrodeposition of bright nanocrystalline nickel

    Institute of Scientific and Technical Information of China (English)

    ZHU ZengWei; ZHU Di; QU NingSong

    2008-01-01

    A new mechanical electrodeposition technology was proposed,and nanocrystal-line nickel deposit with bright and smooth surface was prepared in the bath without any additive agents.Unlike traditional methods,the novel technology employed dynamical hard particles to continuously polish the cathode surface and disturb the nearby solution during electrodepositing.Experimental results showed that the polishing effect of hard particles can effectively prevent the hydrogen bubbles and impurities from adhering on the deposit surface and avoid the production of pits,pinholes and nodules.Furthermore,comparing with the deposit prepared by tradi-tional methods,the one prepared by the novel technology was substantially refined with grain size ranging from 30 to 80 nm.Every diffraction peak's intensity of the deposit was reduced,the preferential orientation degree of (200) decreased and those of (111) and (220) increased.The microhardness notably increased.The magnetic properties were also changed with decreased saturation magnetization and increased coercive force.It was also found that variation of current density and cathode rotational speed could affect the structure and properties of the nickel deposits prepared by this technology.Key.words:electrodeposition,electroforming,hard particle,nanocrystalline,bright nickel deposits prepared by this technology.

  14. Metasomatismo en ortoanfibolitas de la Faja máfica-ultramáfica del río de las tunas, Mendoza Metasomatism in orthoamphibolites from the Río de Las Tunas mafic-ultramafic belt, Mendoza

    Directory of Open Access Journals (Sweden)

    M. Florencia Gargiulo

    2012-06-01

    Full Text Available Se identificaron claras evidencias petro-mineralógicas y químicas de metasomatismo en ortoanfibolitas de la faja máficaultramáfica del Río de Las Tunas, Cordillera Frontal de Mendoza. Estas ortoanfibolitas integran el basamento metamórfico de la Cordillera Frontal y pertenecen al Complejo Guarguaráz. La peculiaridad que poseen, es el desarrollo de asociaciones de minerales calcosilicáticos vinculados a texturas que indican condiciones de desequilibrio. Los cristaloblastos de anfíbol están reemplazados en los bordes por clinopiroxeno (diópsido ferroso y los individuos de plagioclasa se encuentran casi completamente reemplazados por un agregado muy fino de granate-epidotos.l -prehnita-pumpellyita-albita, que actúa a modo de matriz de la roca. Los cristales de anfíbol y clinopiroxeno están, a su vez, parcialmente reemplazados por pumpellyita y/o clorita, mientras que la matriz se encuentra alterada débilmente por muscovita y calcita. Los cristales de granate corresponden a la serie grosularia-andradita y su composición promedio es Alm05Adr53Prp01Sps04Grs36Uv01. Cristales con mayor contenido de Cr2O3 (11,69-13,17% en peso y sutil zonalidad composicional, determinada por un núcleo más rico en el componente uvarovítico: Alm03Adr13Prp00Sps02Grs35Uv47, y borde con incremento de la proporción del componente grosulárico: Alm03Adr12Prp00Sps01Grs44Uv40, suelen estar en contacto con cristales de magnetita con hasta un 20% de componente cromítico. La zonalidad composicional presente también en los cristales de anfíbol permitió estimar valores de presión entre 2,5 y 4,2 kbar. Las asociaciones minerales junto con sus características texturales y químicas distinguen a estas rocas del resto de las ortoanfibolitas que afloran en el área de estudio y se las interpreta y clasifica como rodingitas clinopiroxénicas con granate y clinozoisita. Las condiciones de presión obtenidas, junto con el desarrollo de los minerales calcosilic

  15. Scientific development and modern wine industry: the origins and consolidation of Enology Station of Mendoza (Argentina, 1904-1920 Desarrollo científico e industria vitivinícola moderna: orígenes y consolidación de la Estación Enológica de Mendoza (Argentina, 1904- 1920

    Directory of Open Access Journals (Sweden)

    Florencia Rodríguez Vázquez

    2009-01-01

    Full Text Available In this article we propose to undertake a reconstruction of the development of the 'Estación Enológica', next to 'Escuela Nacional de Vitivinicultura', between 1904 to 1920 in Mendoza province. This study is of vital importance as we consider this place was a pioneer center in the achievement of scientific and technical studies. These were the basis for the consolidation of quality wine industry , which had many shortcomings by then, and they triggered changes in Mendoza's agroindustry. Besides, Estación Enológica became a meeting place for people who graduated from that school to share experiences and concerns. Apart from carrying out the reconstruction of the development, we will also investigate possibilities of applying these studies to vineyardsEn el presente artículo nos proponemos realizar una reconstrucción de la trayectoria de la Estación Enológica de Mendoza, anexa a la Escuela Nacional de Vitivinicultura, desde 1904 a 1920. El mismo cobra vital importancia en tanto la consideramos un centro pionero en la realización de estudios científicos y técnicos que sirvieron de base a la consolidación de una vitivinicultura de calidad -y que por entonces contaba con múltiples deficiencias- y un impulsor de cambios técnicos en la agroindustria local. A su vez, su importancia radicaría en que fue un espacio aglutinador de las experiencias e inquietudes de los enólogos graduados de la mencionada Escuela. Por último, nos referiremos a las posibilidades de recepción y divulgación de los estudios entre los vitivinicultores

  16. Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice

    OpenAIRE

    Menichella, Daniela M; Jayaraj, Nirupa D; Wilson, Heather M; Ren, Dongjun; Flood, Kelsey; Wang, Xiao-Qi; Shum, Andrew; Miller, Richard J.; Paller, Amy S.

    2016-01-01

    Background Small fiber neuropathy is a well-recognized complication of type 2 diabetes and has been shown to be responsible for both neuropathic pain and impaired wound healing. In previous studies, we have demonstrated that ganglioside GM3 depletion by knockdown of GM3 synthase fully reverses impaired wound healing in diabetic mice. However, the role of GM3 in neuropathic pain and small fiber neuropathy in diabetes is unknown. Purpose Determine whether GM3 depletion is able to reverse neurop...

  17. Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway.

    Science.gov (United States)

    Kundu, Manjari; Mahata, Barun; Banerjee, Avisek; Chakraborty, Sohini; Debnath, Shibjyoti; Ray, Sougata Sinha; Ghosh, Zhumur; Biswas, Kaushik

    2016-07-01

    The definitive role of ganglioside GM2 in mediating tumor-induced growth and progression is still unknown. Here we report a novel role of ganglioside GM2 in mediating tumor cell migration and uncovered its mechanism. Data shows differential expression levels of GM2-synthase as well as GM2 in different human cancer cells. siRNA mediated knockdown of GM2-synthase in CCF52, A549 and SK-RC-26B cells resulted in significant inhibition of tumor cell migration as well as invasion in vitro without affecting cellular proliferation. Over-expression of GM2-synthase in low-GM2 expressing SK-RC-45 cells resulted in a consequent increase in migration thus confirming the potential role GM2 and its downstream partners play in tumor cell migration and motility. Further, treatment of SK-RC-45 cells with exogenous GM2 resulted in a dramatic increase in migratory and invasive capacity with no change in proliferative capacity, thereby confirming the role of GM2 in tumorigenesis specifically by mediating tumor migration and invasion. Gene expression profiling of GM2-synthase silenced cells revealed altered expression of several genes involved in cell migration primarily those controlling the integrin mediated signaling. GM2-synthase knockdown resulted in decreased phosphorylation of FAK, Src as well as Erk, while over-expression and/or exogenous GM2 treatment caused increased FAK and Erk phosphorylation respectively. Again, GM2 mediated invasion and Erk phosphorylation is blocked in integrin knockdown SK-RC-45 cells, thus confirming that GM2 mediated migration and phosphorylation of Erk is integrin dependent. Finally, confocal microscopy suggested co-localization while co-immunoprecipitation and surface plasmon resonance (SPR) confirmed direct interaction of membrane bound ganglioside, GM2 with the integrin receptor.

  18. The Role of Monosialoganglioside GM1 in LTP-Induction in Rat Hippocampal Slices

    Institute of Scientific and Technical Information of China (English)

    李永新; 梅镇彤

    1994-01-01

    The effect of monosialoganglioside GM1 of different doses on the long-term potentiation (LTP) of synaptic transmission has been studied in the CA1 region of rat hippocampal slices, and the possible role that calcium ion and NMDA receptor play has also been investigated. The results reveal that larger magnitude of LTP is induced in hippocampal slices pre-incubated with GM1. The dose-response curve appears in diphase, and the largest magnitude of LTP has been obtained at the GM1 concentration of 50 mg/L in incubation ACSF. Moreover, the magnitude of LTP induced from the slices pre-incubated with GM1 at lower calcium ion concentration is similar to that obtained from the control slices at normal calcium ion concentration. Under higher calcium ion concentration, the enhancing effect of GM1 on LTP seems relatively feeble. After NMDA receptors were blocked, no enhancing effect of GM1 was observed. The mechanism of GM1 action on LTP is discussed.

  19. Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease.

    Directory of Open Access Journals (Sweden)

    Takashi Kodama

    Full Text Available To find a new biomarker of Tay-Sachs disease and Sandhoff disease. The lyso-GM2 ganglioside (lyso-GM2 levels in the brain and plasma in Sandhoff mice were measured by means of high performance liquid chromatography and the effect of a modified hexosaminidase (Hex B exhibiting Hex A-like activity was examined. Then, the lyso-GM2 concentrations in human plasma samples were determined. The lyso-GM2 levels in the brain and plasma in Sandhoff mice were apparently increased compared with those in wild-type mice, and they decreased on intracerebroventricular administration of the modified Hex B. The lyso-GM2 levels in plasma of patients with Tay-Sachs disease and Sandhoff disease were increased, and the increase in lyso-GM2 was associated with a decrease in Hex A activity. Lyso-GM2 is expected to be a potential biomarker of Tay-Sachs disease and Sandhoff disease.

  20. RISK MANAGEMENT AND EXPERTISE: UK: Strategies for Precautionary Commercialization of GM Crops

    Directory of Open Access Journals (Sweden)

    Levidow Les

    2000-07-01

    Full Text Available As genetically modified (GM products approach the market stage, the UK government and agro-food industry have faced a suspicious or hostile public. Since 1998 many retail chains have undertaken to exclude any GM-derived ingredients from their own-brand lines. This commercial blockage has intensified pressures for greater precaution, even for a moratorium on cultivating GM crops. Political protest has led to strategies for precautionary commercialization. Government and industry have cooperated to plan a “managed development” of GM crops. Across the agricultural supply chain, industry has devised voluntary guidelines to ensure segregation of GM crops and to limit the spread of GM herbicide-tolerance. In particular UK regulators seek to test the risk that broad-spectrum herbicide sprays could damage wildlife habitats; they have broadened the advisory expertise accordingly. These measures open up the precautionary content to further debate, at both national and EU levels. Market-stage precautions establish a means to test claims that GM crops are environmentally-friendly products. By translating public concerns into broader risk-assessment criteria, the UK procedure involves critics in potentially influencing standards of scientific evidence and environmental harm. This social process has become a prerequisite for legitimizing commercial use.

  1. Responses to GM food content in context with food integrity issues: results from Australian population surveys.

    Science.gov (United States)

    Mohr, Philip; Golley, Sinéad

    2016-01-25

    This study examined community responses to use of genetically modified (GM) content in food in the context of responses to familiar food additives by testing an empirically and theoretically derived model of the predictors of responses to both GM content and food integrity issues generally. A nationwide sample of 849 adults, selected at random from the Australian Electoral Roll, responded to a postal Food and Health Survey. Structural equation modelling analyses confirmed that ratings of general concern about food integrity (related to the presence of preservatives and other additives) strongly predicted negativity towards GM content. Concern about food integrity was, in turn, predicted by environmental concern and health engagement. In addition, both concern about food integrity generally and responses to GM content specifically were weakly predicted by attitudes to benefits of science and an intuitive (i.e., emotionally-based) reasoning style. Data from a follow-up survey conducted under the same conditions (N=1184) revealed that ratings of concern were significantly lower for use of genetic engineering in food than for four other common food integrity issues examined. Whereas the question of community responses to GM is often treated as a special issue, these findings support the conclusion that responses to the concept of GM content in food in Australia are substantially a specific instance of a general sensitivity towards the integrity of the food supply. They indicate that the origins of responses to GM content may be largely indistinguishable from those of general responses to preservatives and other common food additives.

  2. Genetically modified food in the news: media representations of the GM debate in the UK.

    Science.gov (United States)

    Augoustinos, Martha; Crabb, Shona; Shepherd, Richard

    2010-01-01

    This paper analyses a corpus of articles on GM crops and food which appeared in six UK newspapers in the first three months of 2004, the year following the GM Nation? debate (2003). Using the methods of critical discourse analysis we focus on how specific and pervasive representations of the major stakeholders in the national debate on GM--the British public, the British government, the science of GM, and biotechnology companies--served significant rhetorical functions in the controversy. Of particular significance was the pervasive representation of the British public as uniformly opposed to GM crops and food which served rhetorically to position the British government as undemocratic and as being beholden to powerful political and economic interests. Of significance also in our analysis, is how the science of GM farming itself became a highly contested arena. In short, our analysis demonstrates how the GM debate was represented in the newsprint media as a "battleground" of competing interests. We conclude by considering the possible implications of this representation given the increasing emphasis placed on the importance of deliberative and inclusive forms of science policy decision-making.

  3. Don Juan de Palafox y Mendoza, promotor del libre acceso a la información en el siglo XVII novo-hispano Don Juan de Palafox y Mendoza promoter of free access to information in the eighteenth century in New Spain

    OpenAIRE

    Rosa María Fernández de Zamora

    2011-01-01

    Don Juan de Palafox y Mendoza, arzobispo y virrey de la Nueva España y obispo de Puebla en el siglo XVII, ha sido motivo de numerosos estudios, pero lo que se desea resaltar en este escrito es su labor como fundador de la primera biblioteca pública de México y del continente americano, misma que hoy conocemos como Biblioteca Palafoxiana, y como promotor del libre acceso a la información. En el siglo XVIII, el obispo de Puebla, Francisco Fabián y Fuero, seguidor de las ideas de Palafox, enriqu...

  4. La producción y función de la cerámica indígena durante la dominación incaica y la colonia en Mendoza (Argentina The production and function of indigenous ceramic during the inca domination and the colony in Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Cristina Prieto Olavarría

    2012-07-01

    Full Text Available A partir del análisis tecnológico de las elecciones de manufactura tomadas para confeccionar la cerámica Viluco (provincia de Mendoza, Argentina, evaluamos aspectos vinculados a los contextos producción, uso y consumo de las vasijas, los que estuvieron influenciados por la dominación que ejercieron incas y espanoles sobre la población local huarpe entre los siglos XV y XVII. Los resultados obtenidos permiten sostener que la cerámica Viluco surgió y se desarrolló bajo presiones sociales, políticas, económicas y simbólicas impuestas por los incas y que, si bien su producción fue descentralizada en los contextos del valle de Mendoza, refleja las relaciones sostenidas entre esta población y los dominadores. Por otra parte, su función estuvo ligada al estatus e identidad, ya que se usó como mediador visual entre las jefaturas locales y entre éstas y los dominadores. Este desempeno se proyectó al período colonial, cuando este conjunto permitió a los grupos huarpe mantener un nexo de identidad con la anterior dominación inca, si bien existen indicadores de que la producción alfarera pudo estar bajo control espanol.Aspects related to production environments, use and consumption of Viluco ceramics from Mendoza province, Argentina, are evaluated on the basis of the technological analysis of manufacturing choices, which were influenced by the Inca and Spanish domination of the local Huarpe population between the fifteenth and sixteenth centuries AD. The results show that Viluco pottery emerged and developed under social, political, economic and symbolic pressure imposed by the Incas, and while its production was decentralized in the Mendoza valley contexts, it reflects sustained relationships among this population and the dominant power. The function of the pottery was linked to status and identity, and was used as a visual mediator among local leaders and between these and their Inca rulers. This performance was continued into the

  5. Decoupling polarization of the Golgi apparatus and GM1 in the plasma membrane.

    Science.gov (United States)

    Bisel, Blaine; Calamai, Martino; Vanzi, Francesco; Pavone, Francesco Saverio

    2013-01-01

    Cell polarization is a process of coordinated cellular rearrangements that prepare the cell for migration. GM1 is synthesized in the Golgi apparatus and localized in membrane microdomains that appear at the leading edge of polarized cells, but the mechanism by which GM1 accumulates asymmetrically is unknown. The Golgi apparatus itself becomes oriented toward the leading edge during cell polarization, which is thought to contribute to plasma membrane asymmetry. Using quantitative image analysis techniques, we measure the extent of polarization of the Golgi apparatus and GM1 in the plasma membrane simultaneously in individual cells subject to a wound assay. We find that GM1 polarization starts just 10 min after stimulation with growth factors, while Golgi apparatus polarization takes 30 min. Drugs that block Golgi polarization or function have no effect on GM1 polarization, and, conversely, inhibiting GM1 polarization does not affect Golgi apparatus polarization. Evaluation of Golgi apparatus and GM1 polarization in single cells reveals no correlation between the two events. Our results indicate that Golgi apparatus and GM1 polarization are controlled by distinct intracellular cascades involving the Ras/Raf/MEK/ERK and the PI3K/Akt/mTOR pathways, respectively. Analysis of cell migration and invasion suggest that MEK/ERK activation is crucial for two dimensional migration, while PI3K activation drives three dimensional invasion, and no cumulative effect is observed from blocking both simultaneously. The independent biochemical control of GM1 polarity by PI3K and Golgi apparatus polarity by MEK/ERK may act synergistically to regulate and reinforce directional selection in cell migration.

  6. Response to issues on GM agriculture in Africa: Are transgenic crops safe?

    Directory of Open Access Journals (Sweden)

    Adenle Ademola A

    2011-10-01

    Full Text Available Abstract The controversies surrounding transgenic crops, often called Genetically Modified Organisms (GMOs, call for a need to raise the level of public awareness of Genetic Modification (GM technology in Africa. This should be accomplished by educating the public about the potential benefits and risks that may be associated with this new technology. In the last 15 years, GM crop producing countries have benefited from adoption of this new technology in the form of improved crop productivity, food security, and quality of life. The increased income to resource-poor farmers is a key benefit at the individual level especially as most countries using this technology are in the developing world, including three African countries (South Africa, Burkina Faso and Egypt. Despite clear benefits to countries and farmers who grow GMOs, many people are concerned about suspected potential risks associated with GMOs. This sparks debate as to whether GM technology should be adopted or not. Given the concerns regarding the safety of GMO products, thorough scientific investigation of safe application of GMOs is required. The objective of this paper is to respond to the issues of GM agriculture in Africa and some of the issues surrounding the adoption of GM crops between developed and developing countries. In this article, I analyse relevant papers relating to the adoption of GM technology particularly in developing countries including the few African countries that have adopted GM crops. The issues discussed span a wide range including: safety; potential benefits and risks; disputes between the United States of America (USA and the European Union (EU over adoption of GM crops with a focus on Africa continent. This article is concluded by summarising the issues raised and how GM technology can be adopted for agricultural development in Africa.

  7. Granulocyte macrophage colony stimulating factor (GM-CSF biological actions on human dermal fibroblasts

    Directory of Open Access Journals (Sweden)

    S Montagnani

    2009-12-01

    Full Text Available Fibroblasts are involved in all pathologies characterized by increased ExtraCellularMatrix synthesis, from wound healing to fibrosis. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF is a cytokine isolated as an hemopoietic growth factor but recently indicated as a differentiative agent on endothelial cells. In this work we demonstrated the expression of the receptor for GM-CSF (GMCSFR on human normal skin fibroblasts from healthy subjects (NFPC and on a human normal fibroblast cell line (NHDF and we try to investigate the biological effects of this cytokine. Human normal fibroblasts were cultured with different doses of GM-CSF to study the effects of this factor on GMCSFR expression, on cell proliferation and adhesion structures. In addition we studied the production of some Extra-Cellular Matrix (ECM components such as Fibronectin, Tenascin and Collagen I. The growth rate of fibroblasts from healthy donors (NFPC is not augmented by GM-CSF stimulation in spite of increased expression of the GM-CSFR. On the contrary, the proliferation of normal human dermal fibroblasts (NHDF cell line seems more influenced by high concentration of GM-CSF in the culture medium. The adhesion structures and the ECM components appear variously influenced by GM-CSF treatment as compared to fibroblasts cultured in basal condition, but newly only NHDF cells are really induced to increase their synthesis activity. We suggest that the in vitro treatment with GM-CSF can shift human normal fibroblasts towards a more differentiated state, due or accompanied by an increased expression of GM-CSFR and that such “differentiation” is an important event induced by such cytokine.

  8. The cytokine network of wallerian degeneration: IL-10 and GM-CSF.

    Science.gov (United States)

    Be'eri, H; Reichert, F; Saada, A; Rotshenker, S

    1998-08-01

    Wallerian degeneration (WD) is the inflammatory response of peripheral nerves to injury. Evidence is provided that granulocyte macrophage colony stimulating factor (GM-CSF) contributes to the initiation and progression of WD by activating macrophages and Schwann, whereas IL-10 down-regulates WD by inhibiting GM-CSF production. A significant role of activated macrophages and Schwann for future regeneration is myelin removal by phagocytosis and degradation. We studied the timing and magnitude of GM-CSF and IL-10 production, macrophage and Schwann activation, and myelin degradation in C57BL/6NHSD and C57BL/6-WLD/OLA/NHSD mice that display normal rapid-WD and abnormal slow-WD, respectively. We observed the following events in rapid-WD. The onset of GM-CSF production is within 5 h after injury. Production is steadily augmented during the first 3 days, but is attenuated thereafter. The onset of production of the macrophage and Schwann activation marker Galectin-3/MAC-2 succeeds that of GM-CSF. Galectin-3/MAC-2 production is up-regulated during the first 6 days, but is down-regulated thereafter. The onset of myelin degradation succeeds that of Galectin-3/MAC-2, and is almost complete within 1 week. IL-10 production displays two phases. An immediate low followed by a high that begins on the fourth day, reaching highest levels on the seventh. The timing and magnitude of GM-CSF production thus enable the rapid activation of macrophages and Schwann that consequently phagocytose and degrade myelin. The timing and magnitude of IL-10 production suggest a role in down-regulating WD after myelin is removed. In contrast, slow-WD nerves produce low inefficient levels of GM-CSF and IL-10 throughout. Therefore, deficient IL-10 levels cannot account for inefficient GM-CSF production, whereas deficient GM-CSF levels may account, in part, for slow-WD.

  9. MafB antagonizes phenotypic alteration induced by GM-CSF in microglia

    Energy Technology Data Exchange (ETDEWEB)

    Koshida, Ryusuke, E-mail: rkoshida-myz@umin.ac.jp; Oishi, Hisashi, E-mail: hoishi@md.tsukuba.ac.jp; Hamada, Michito; Takahashi, Satoru

    2015-07-17

    Microglia are tissue-resident macrophages which are distributed throughout the central nervous system (CNS). Recent studies suggest that microglia are a unique myeloid population distinct from peripheral macrophages in terms of origin and gene expression signature. Granulocyte-macrophage colony-stimulating factor (GM-CSF), a pleiotropic cytokine regulating myeloid development, has been shown to stimulate proliferation and alter phenotype of microglia in vitro. However, how its signaling is modulated in microglia is poorly characterized. MafB, a bZip transcriptional factor, is highly expressed in monocyte-macrophage lineage cells including microglia, although its role in microglia is largely unknown. We investigated the crosstalk between GM-CSF signaling and MafB by analyzing primary microglia. We found that Mafb-deficient microglia grew more rapidly than wild-type microglia in response to GM-CSF. Moreover, the expression of genes associated with microglial differentiation was more downregulated in Mafb-deficient microglia cultured with GM-CSF. Notably, such differences between the genotypes were not observed in the presence of M-CSF. In addition, we found that Mafb-deficient microglia cultured with GM-CSF barely extended their membrane protrusions, probably due to abnormal activation of RhoA, a key regulator of cytoskeletal remodeling. Altogether, our study reveals that MafB is a negative regulator of GM-CSF signaling in microglia. These findings could provide new insight into the modulation of cytokine signaling by transcription factors in microglia. - Highlights: • GM-CSF alters the phenotype of microglia in vitro more potently than M-CSF. • Transcription factor MafB antagonizes the effect of GM-CSF on microglia in vitro. • MafB deficiency leads to RhoA activation in microglia in response to GM-CSF. • We show for the first time the function of MafB in microglia.

  10. Historical Glacier Variations in Southern South America since the Little Ice Age: Examples from Lago Viedma (Southern Patagonia) and Mendoza (Central Andes), Argentina

    Science.gov (United States)

    Nussbaumer, S. U.; Masiokas, M.; Pitte, P.; Berthier, E.; Guerrido, C.; Luckman, B. H.; Villalba, R.

    2013-12-01

    The evaluation of historical information can give valuable insight into past glacier dynamics, especially before the onset of modern measurements. Early photographs and maps depict changes for selected glaciers in southern South America. Within this study, written documents and pictorial historical records (drawings, sketches, engravings, photographs, chronicles, topographic maps) are analysed critically, with a particular focus on two regions: Lago Viedma (El Chaltén, southern Patagonia, 49.5°S, 73.0°W) and the Río Mendoza basin (Mendoza, central Andes, 33.1°S, 69.9°W). For the Lago Viedma area, early historical data for the end of the 19th century stem from the expedition of the Chilean-Argentinean border commission. In addition, the expedition by the German Scientific Society, conducted between 1910 and 1916, and the later photographs by Alberto M. de Agostini give an excellent depiction of the glaciers. Glaciar Viedma is a calving glacier which shows distinct retreat from 1896 until the present (though with a stationary or possibly advancing glacier front between 1930/31 and 1951/52), similar to the neighbouring glaciers. On the contrary, nearby Glaciar Perito Moreno shows an exceptional behaviour: the glacier front has been advancing during the first half of the 20th century, staying in an advanced position until the present. At the beginning of the 20th century, Robert Helbling explored the Argentinean-Chilean Andes together with his friend Friedrich Reichert. In the summer of 1909/10, they started a detailed survey of the highly glacierized Juncal-Tupungato mountains (Río Mendoza basin), leading to the first accurate topographic map of the area published in 1914. Its outstanding quality allows a comparison with contemporary satellite imagery. The area received attention in 1934, when the sudden drainage of a glacier-dammed lake in the upper Río del Plomo valley caused fatalities and considerable damage to constructions and the Transandine Railway. A

  11. File list: NoD.Epd.20.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Epd.20.AllAg.Fibrobl_GM03348 hg19 No description Epidermis Fibrobl GM03348 http...://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Epd.20.AllAg.Fibrobl_GM03348.bed ...

  12. File list: NoD.Epd.10.AllAg.Fibrobl_GM03348 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Epd.10.AllAg.Fibrobl_GM03348 hg19 No description Epidermis Fibrobl GM03348 http...://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Epd.10.AllAg.Fibrobl_GM03348.bed ...

  13. GM338电台在VE432可控震源上的应用

    Institute of Scientific and Technical Information of China (English)

    马立宗

    2011-01-01

    VE432可控震源控制系统原配电台为GM300,因使用环境恶劣、使用年限长,电台性能下降,故障率上升。因此,决定用性能稳定、抗振动、耐高温的同系列的新型电台GM338代替GM300。但GM338电台直接代替GM300电台与VE432可控震源控制系统匹配使用,必须进行相应的改进。本文详细地分析了GM338电台的电路特点,介绍了具体的改进方法。%The original radio type for VE432 control system is GM300. The poor conditions and long service life resulted in increasing failure rates. Another new type radio, GM338 with stable performance and anti-vibration function as well as high working temperature, is often adopted to replace GM300. To match with VE432 well, some transfor- mation should be done to GM338 and GM300. This paper analyzes the circuit characteristics of GM338 radio and in- troduces the detailed method for transformation.

  14. INVESTIGATION ON THE CAUSES OF EUCALYPTUS KRAFT PULP BRIGHTNESS REVERSION

    Directory of Open Access Journals (Sweden)

    Kátia M. M. Eiras

    2005-12-01

    Full Text Available Some high brightness eucalyptus Kraft pulps have shown poor brightness stability. In most cases, the causes have notbeen identified and permanent solutions have not been found. This work focused on evaluating the brightness stability profile of pulpsbleached by in sequences such as O(DC(PODD, O(DC(PODP, OD(PODD, OD(PODP, ODHT(PODD, ODHT(PODP, OA/D(PODD, OA/D(PODP, OAD(PODD and O(ZeD(PO. Brightness stability tests induced by according to Tappi UM200 procedureon samples bleached to 90±0.5% ISO. Brightness stability was measured after each bleaching stage of the various sequences andexpressed as brightness loss in % ISO. The results indicate that pulps bleached with sequences ending with a peroxide stage havehigher brightness stability compared to those ending with a chlorine dioxide stage. Pulps bleached with a standard sequence, initiatingwith a (DC stage, show brightness stability similar to that of pulp bleached by an ECF (Elementary chlorine free sequence initiatingwith a regular D0 stage. ECF sequences, initiated with hot stages produce pulps with higher brightness stability than sequencesinitiating with a regular D0 stage. The profile across the bleaching sequences shows a tendency of increased brightness stability inalkaline stages containing peroxide and decreased stability in those stages containing chlorine and/or chlorine dioxide, parallelingpulp carbonyl group content.

  15. Soybean GmPHD-Type Transcription Regulators Improve Stress Tolerance in Transgenic Arabidopsis Plants

    OpenAIRE

    Wei Wei; Jian Huang; Yu-Jun Hao; Hong-Feng Zou; Hui-Wen Wang; Jing-Yun Zhao; Xue-Yi Liu; Wan-Ke Zhang; Biao Ma; Jin-Song Zhang; Shou-Yi Chen

    2009-01-01

    BACKGROUND: Soybean [Glycine max (L.) Merr.] is one of the most important crops for oil and protein resource. Improvement of stress tolerance will be beneficial for soybean seed production. PRINCIPAL FINDINGS: Six GmPHD genes encoding Alfin1-type PHD finger protein were identified and their expressions differentially responded to drought, salt, cold and ABA treatments. The six GmPHDs were nuclear proteins and showed ability to bind the cis-element "GTGGAG". The N-terminal domain of GmPHD play...

  16. Coupling Bright and Dark Plasmonic Lattice Resonances

    CERN Document Server

    Rodriguez, S R K; Maes, B; Janssen, O T A; Vecchi, G; Rivas, J Gomez

    2011-01-01

    We demonstrate the coupling of bright and dark Surface Lattice Resonances (SLRs), which are collective Fano resonances in 2D plasmonic crystals. As a result of this coupling, a frequency stop-gap in the dispersion relation of SLRs is observed. The different field symmetries of the low and high frequency SLR bands lead to pronounced differences in their coupling to free space radiation. Standing waves of very narrow spectral width compared to localized surface plasmon resonances are formed at the high frequency band edge, while subradiant damping onsets at the low frequency band edge leading the resonance into darkness. We introduce a coupled oscillator analog to the plasmonic crystal, which serves to elucidate the physics of the coupled plasmonic resonances and to estimate very high quality factors (Q>700) for SLRs, which are the highest known for any 2D plasmonic crystal.

  17. Hybrid quantum repeater using bright coherent light.

    Science.gov (United States)

    van Loock, P; Ladd, T D; Sanaka, K; Yamaguchi, F; Nemoto, Kae; Munro, W J; Yamamoto, Y

    2006-06-23

    We describe a quantum repeater protocol for long-distance quantum communication. In this scheme, entanglement is created between qubits at intermediate stations of the channel by using a weak dispersive light-matter interaction and distributing the outgoing bright coherent-light pulses among the stations. Noisy entangled pairs of electronic spin are then prepared with high success probability via homodyne detection and postselection. The local gates for entanglement purification and swapping are deterministic and measurement-free, based upon the same coherent-light resources and weak interactions as for the initial entanglement distribution. Finally, the entanglement is stored in a nuclear-spin-based quantum memory. With our system, qubit-communication rates approaching 100 Hz over 1280 km with fidelities near 99% are possible for reasonable local gate errors.

  18. Brightness temperature for 166 radio sources

    Institute of Scientific and Technical Information of China (English)

    Jun-Hui Fan; Yong Huang; Yu-Hai Yuan; Jiang-He Yang; Yi Liu; Jun Tao; Ying Gao; Tong-Xu Hua; Rui-Guang Lin; Jiang-Shui Zhang; Jing-Yi Zhang; Yi-Ping Qin

    2009-01-01

    Using the database of the University of Michigan Radio Astronomy Observatory (UMRAO) at three radio frequencies (4.8, 8 and 14.5 GHz), we determined the short-term variability timescales for 166 radio sources. The timescales are 0.15d (2007+777) to 176.17d (0528-250) with an average timescale of △tobs=17.1±16.5d for the whole sample. The timescales are used to calculate the brightness temperatures, TB. The value of log TB is in the range of log TB = 10.47 to 19.06 K. In addition, we also estimated the boosting factor for the sources. The correlation between the polarization and the Doppler factor is also discussed.

  19. Substructure of Quiet Sun Bright Points

    CERN Document Server

    Andic, Aleksandra; Goode, Phillip R

    2010-01-01

    Since photospheric bright points (BPs) were first observed, there has been a question as to how are they structured. Are they just single flux tubes or a bundle of the flux-tubes? Surface photometry of the quiet Sun (QS) has achieved resolution close to 0.1" with the New Solar Telescope at Big Bear Solar Observatory. This resolution allowed us to detect a richer spectrum of BPs in the QS. The smallest BPs we observed with TiO 705.68 nm were 0.13", and we were able to resolve individual components in some of the BPs clusters and ribbons observed in the QS, showing that they are composed of the individual BPs. Average size of observed BPs was 0.22".

  20. Dark Skies, Bright Kids Year 8

    Science.gov (United States)

    Bittle, Lauren E.; Wenger, Trey; Johnson, Kelsey E.; Angell, Dylan; Burkhardt, Andrew; Davis, Blair; Firebaugh, Ariel; Hancock, Danielle; Richardson, Whitney; Rochford Hayes, Christian; Linden, Sean; Liss, Sandra; Matthews, Allison; McNair, Shunlante; Prager, Brian; Pryal, Matthew; Troup, Nicholas William

    2017-01-01

    We present activities from the eighth year of Dark Skies Bright Kids (DSBK), an entirely volunteer-run outreach organization based out of the Department of Astronomy at the University of Virginia. Our core mission is to enhance elementary science education and literacy in Central Virginia through fun, hands-on activities that introduce basic Astronomy concepts. Over the past seven years, our primary focus has been hosting an 8-10 week after-school astronomy club at underserved elementary and middle schools, and over the past several years, we have partnered with local businesses to host our Annual Central Virginia Star Party, a free event open to the community featuring star-gazing and planetarium shows. This past summer we expanded our reach through a new initiative to bring week-long summer day camps to south and southwest Virginia, home to some of the most underserved communities in the commonwealth.

  1. Tunneling Dynamics Between Atomic Bright Solitons

    CERN Document Server

    Zhao, Li-Chen; Yang, Zhan-Ying; Yang, Wen-Li

    2016-01-01

    We investigate tunneling behavior between two bright solitons in a Bose-Einstein condensate with attractive contact interactions between atoms. The explicit tunneling properties including tunneling particles and oscillation period are described analytically, which indicates that the periodic tunneling form is a nonlinear Josephson type oscillation. The results suggest that the breathing behavior of solitons comes from the tunneling mechanism in an effective double-well potential, which is quite different from the modulational instability mechanism for Akhmediev breather and K-M breather. Furthermore, we obtain a phase diagram for two soliton interaction which admits tunneling property, particle-like property, interference property, and a resonant interaction case. The explicit conditions for them are clarified based on the defined critical distance $d_c$ and spatial interference period $D$.

  2. RECOMPOSICIÓN ECONÓMICA DE LAS BURGUESÍAS REGIONALES: LA BURGUESÍA VITIVINÍCOLA EN LA PROVINCIA DE MENDOZA, ARGENTINA (1990-2011

    Directory of Open Access Journals (Sweden)

    ADRIANA CHAZARRETA

    2014-01-01

    Full Text Available Este artículo se propone comprender la recomposición de la burguesía vitivinícola en Mendoza a partir de la reestructuración de la actividad que comienza a principios de los `90. Este trabajo permite mostrar el peso relevante que en la estructura económica, aún conservan los sectores ligados a capitales locales y/o nacionales, pese al considerable ingreso de empresas transnacionales y extranjeras. El diseño de investigación se basa en una estrategia de triangulación metodológica, combinando técnicas de recolección de datos cuantitativos y cualitativos, y el uso de distintas fuentes de datos secundarias y primarias.

  3. Necesidad de transparencia y legalidad en la gestión y uso de las aguas subterráneas (El reciente caso de la Provincia de Mendoza

    Directory of Open Access Journals (Sweden)

    María Valentina Erice

    2013-12-01

    Full Text Available En Mendoza las aguas subterráneas son un recurso natural indispensable para la subsistencia y de gran importancia para el desarrollo provincial, ya que tienen un valor no solo económico y estratégico, sino también social y ambiental. La prevención de la sobreexplotación de los acuíferos y de la contaminación de estas aguas constituye una de las preocupaciones más serias a la que se enfrentan los encargados de gestionar su uso eficiente. Para ello resulta necesario aplicar políticas de ahorro y conservación, contar con un moderno Derecho de aguas preciso, claro, coherente y conservacionista, encaminado a dar soluciones eficaces a los problemas que hoy se nos presentan y que la gestión se realice con rectitud, transparencia y respetando la Constitución y la leyes.

  4. Justicia de proximidad y gobierno político-militar en la frontera. Equipamiento institucional del Valle de Uco (Mendoza durante el proceso revolucionario (1810-1820

    Directory of Open Access Journals (Sweden)

    Eugenia Molina

    2014-12-01

    Full Text Available El trabajo reconstruye el proceso de equipamiento institucional de la campaña sur de Mendoza durante el proceso revolucionario. Focaliza la atención en la trama de funcionarios designados para la villa de San Carlos y el Valle de Uco, con el objetivo de  mostrar las articulaciones entre justicia de proximidad, gobierno político-militar y construcción de la legitimidad. La hipótesis es que las propias características de un espacio de frontera se complejizaron en el contexto de guerra, atravesaron la territorialización de este ámbito de la jurisdicción mendocina al hacer que la solución de la cuestión de la distancia tuviera un rol clave en las estrategias para gobernarlo.

  5. Conflictos sociales en Mendoza entre dos crisis, 1890-1916: Una larga lucha de los trabajadores por la conquista de sus derechos laborales

    Directory of Open Access Journals (Sweden)

    Rodolfo Richard-Jorba

    2010-06-01

    Full Text Available Este artículo contribuye a la reconstrucción de la historia del mundo de los trabajadores en Mendoza. Las fuentes revisadas y la sistematización de información dispersa han permitido profundizar en los conocimientos hasta ahora generados, sacando a luz una parte significativa del desarrollo capitalista centrado en la agroindustria vitivinícola. Las fuentes principales para seguir los conflictos han sido los diarios mendocinos, por lo que nuestro abordaje constituye una aproximación que esperamos poder ampliar en el futuro. En este artículo presentamos los conflictos sociales en el contexto de períodos de crisis y de auge económico. Comenzamos por la crisis de 1890 y concluimos con la crisis provocada por la Primera Guerra Mundial y los cambios políticos que sobrevendrían a partir de 1916-1918

  6. 顾及模型误差补偿的GM(1,1)变形预测建模%OPTIMAL METHOD FOR GM (1,1) MODELING FOR PREDICTION OF DEFORMATION TAKING COMPENSATION FOR MODEL ERRORS INTO ACOUNT

    Institute of Scientific and Technical Information of China (English)

    高宁; 崔希民; 高彩云

    2012-01-01

    By analyzing the main error source in the GM (1,1) modeling, the GM (1,1) model taking the compensation for model error was proposed and then, through an example, compared the model ( with compensation for error) with the results predicted with conventional models GM(1,1), PGM(1,1) and time-varying GM (1,1). The results show that the prediction accuracy with the model GM (1,1) of error compensation is the highest.%分析GM(1,1)建模过程中模型误差的主要来源,建立顾及模型误差补偿的GM(1,1)模型,并通过实例将模型误差补偿后的GM(1,1)模型与传统GM(1,1)、PGM(1,1)和时变GM(1,1)模型的预测结果进行比较,结果表明,模型误差补偿后的GM(1,1)模型预测精度最高.

  7. Stability of Bright Solitons in Bose-Einstein Condensates

    Institute of Scientific and Technical Information of China (English)

    YU Hui-You; YAN Jia-Ren; XIE Qiong-Tao

    2004-01-01

    We investigate the stability of bright solitons in Bose-Einstein condensates by including a feeding term and a loss one in the Gross-Pitaevskii equation. Based on the direct approach of perturbation theory for the nonlinear Schrodinger equation, we give the explicit dependence of the height and other related quantities of bright solitons on the feeding and loss term. It is found that the three-body recombination loss plays a crucial role in stabilizing bright solitons.

  8. Research on Brightness Measurement of Intense Electron Beam

    CERN Document Server

    Wang, Yuan; Zhang, Huang; Yang, GuoJun; Li, YiDing; Li, Jin

    2015-01-01

    The mostly research fasten on high emission density of injector to study electron beam's brightness in LIA. Using the injector(2MeV) was built to research brightness of multi-pulsed high current(KA) electron beam, and researchs three measurement method (the pepper-pot method, beam collimator without magnetic field, beam collimator with magnetic field method) to detect beam's brightness with time-resolved measurement system.

  9. Mendoza, Argentina. El terremoto de 1861 como disparador del cambio de representación social de la identidad de una ciudad al pie de los Andes

    Directory of Open Access Journals (Sweden)

    Jorge Ricardo Ponte

    2007-12-01

    Full Text Available The definition of a town´s identity is a contemporary problematic. The process of economic globalization, far from devastating with the regional or national particularities seems to have exacerbated them. For that reason, to look for the bases of the national or regional identity in the present forces to be dig in our own history to try to find out the real or mythical origins of the same one. But the identity is not an easy or univocal concept or of an immediate apprehension. It was neither in the past nor in the present. For that reason, this article aims to introduce the problematic of the identity form the theory of the social representations and as a case applied to the City of Mendoza, Argentina.//La definición de la identidad de los pueblos es una problemática de absoluta vigencia contemporánea. El proceso de globalización económica vigente, lejos de arrasar con las particularidades regionales o nacionales parece que, en cambio, las ha exacerbado.Por ello, buscar las bases de la identidad nacional o regional en el presente, obliga a remitirse a la propia historia para tratar de escudriñar los orígenes reales o míticos de la misma. Pero la identidad no es un concepto unívoco o de fácil e inmediata aprehensión, ni el presente, ni el pasado. Por ello, este artículo apunta a presentar la problemática de la identidad vista desde la teoría de las representaciones sociales y como caso aplicado a la Ciudad de Mendoza, Argentina.

  10. Morfometría de la escarpa de falla histórica identificada al norte del cerro La Cal, zona de falla La Cal, Mendoza

    Directory of Open Access Journals (Sweden)

    F. Mingorance

    2006-12-01

    Full Text Available Investigación morfométrica y paleosísmica histórica fue llevada a cabo en el Norte de Mendoza con el objeto de caracterizar y cuantificar a las evidencias geomorfológicas de ruptura superficial histórica identificadas en el sector septentrional de la zona de falla La Cal. Integración e interpretación de datos e información científica multidisciplinaria, sugieren fuertemente que la ruptura superficial histórica identificada estuvo asociada al terremoto destructivo de Mendoza ocurrido en 1861. La deformación superficial histórica ocurrió casi en su totalidad a lo largo de una escarpa prehistórica previa, mediante una combinación de fallamiento de corrimiento y plegamiento cercano a la superficie. Dos elementos de pendiente históricos de bajo relieve fueron reconocidos en la escarpa compuesta Villavicencio Sur, los cuales se diferencian de la típica secuencia de formas desarrollada en escarpas de falla normal históricas. El "remanente de cara libre", el elemento de pendiente superior, y la "pendiente de colapso", el elemento inferior, son controlados por la fricción interna y por la gravedad y la fricción de deslizamiento del material aluvial, respectivamente. La metodología paleosísmica histórica discutida en este trabajo, parece ser particularmente útil en el período de tiempo que cubre la mayor parte del registro histórico de terremotos destructivos en Argentina, los pasados 350 años, lapso en el cual la mayoría de los métodos de datación absoluta no son muy efectivos.

  11. Solar energy use feasibility and foreseeable impacts of the recent reforms to the urban and building code: Proposals for the city of Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    Mariela Edith Arboit

    2012-06-01

    Full Text Available El objetivo del trabajo es generar conocimientos que permitan realizar propuestas conducentes a una mayor sostenibilidad energético-ambiental de los sistemas urbanos regionales, en función de sus características morfológicas y del recurso solar disponible. En una primera etapa se ha realizado un análisis de las zonas de alta densidad edilicia a partir de los resultados de indicadores relevantes y su análisis estadístico. Los indicadores expresan relaciones entre morfología urbana y acceso al recurso solar en el Área Metropolitana de Mendoza (AMM, e incluyen: Factor de Asoleamiento Efectivo (FAE y el Factor de Asoleamiento Volumétrico (FAV. Los resultados del análisis estadístico han permitido evaluar las correlaciones de cada variable morfológica sobre cada indicador, según distintas alternativas morfológicas y combinaciones de las mismas, lo que constituye la parte sustancial de este trabajo. En una segunda etapa se presentan los resultados parciales de un estudio que tiene como objetivo determinar los impactos energéticos ambientales de las recientes reformas del Código Urbano y de Edificación de la ciudad en estudio, en función del FAV y estimar la reducción del acceso al recurso solar respecto a la situación de referencia (actual, sin cambios y situación futura, en una ciudad con el carácter único de Mendoza como “ciudad-oasis”. Los resultados obtenidos hasta el momento indican que la reducción de la energía solar disponible por unidad de volumen construido sería sustancial: 46,32% para muros al norte y 60,38% techos.

  12. Africa's inevitable walk to genetically modified (GM) crops: opportunities and challenges for commercialization.

    Science.gov (United States)

    Okeno, James A; Wolt, Jeffrey D; Misra, Manjit K; Rodriguez, Lulu

    2013-01-25

    High relative poverty levels in Africa are attributed to the continent's under performing agriculture. Drought, low-yielding crop varieties, pests and diseases, poor soils, low fertilizer use, limited irrigation and lack of modern technologies are among the problems that plague African agriculture. Genetically modified (GM) crops may possess attributes that can help overcome some of these constraints, but have yet to be fully embraced in the mix of technology solutions for African agriculture. Cognizant of this, South Africa, Burkina Faso and Egypt are steadily growing GM crops on a commercial scale. Countries like Kenya, Nigeria, and Uganda are increasingly field-testing these crops with the view to commercialize them. These countries show strong government support for GM technology. Progress by these first adopter nations provides an insight as to how GM crops are increasingly being viewed as one of the ways in which the continent can invigorate the agriculture sector and achieve food security.

  13. Stability of GM(1,1) power model on vector transformation

    Institute of Scientific and Technical Information of China (English)

    Jinhai Guo; Xinping Xiao; Jun Liu; Shu hua Mao

    2015-01-01

    The morbidity problem of the GM(1,1) power model in parameter identification is discussed by using multiple and rota-tion transformation of vectors. Firstly we consider the morbidity problem of the special matrix and prove that the condition num-ber of the coefficient matrix is determined by the ratio of lengths and the included angle of the column vector, which could be ad-justed by multiple and rotation transformation to turn the matrix to a wel-conditioned one. Then partition the corresponding matrix of the GM(1,1) power model in accordance with the column vector and regulate the matrix to a wel-conditioned one by multiple and rotation transformation of vectors, which completely solve the in-stability problem of the GM(1,1) power model. Numerical results show that vector transformation is a new method in studying the stability problem of the GM(1,1) power model.

  14. Assessment of the safety of foods derived from genetically modified (GM) crops

    DEFF Research Database (Denmark)

    Konig, A.; Cockburn, A.; Crewel, R. W. R.

    2004-01-01

    This paper provides guidance on how to assess the safety of foods derived from genetically modified crops (GM crops); it summarises conclusions and recommendations of Working Group I of the ENTRANSFOOD project. The paper provides an approach for adapting the test strategy to the characteristics...... of the modified crop and the introduced trait, and assessing potential unintended effects from the genetic modification. The proposed approach to safety assessment starts with the comparison of the new GM crop with a traditional counterpart that is generally accepted as safe based on a history of human food use...... (the concept of substantial equivalence). This case-focused approach ensures that foods derived from GM crops that have passed this extensive test-regime are as safe and nutritious as currently consumed plant-derived foods. The approach is suitable for current and future GM crops with more complex...

  15. Study of Three-Dimensional Image Brightness Loss in Stereoscopy

    Directory of Open Access Journals (Sweden)

    Hsing-Cheng Yu

    2015-10-01

    Full Text Available When viewing three-dimensional (3D images, whether in cinemas or on stereoscopic televisions, viewers experience the same problem of image brightness loss. This study aims to investigate image brightness loss in 3D displays, with the primary aim being to quantify the image brightness degradation in the 3D mode. A further aim is to determine the image brightness relationship to the corresponding two-dimensional (2D images in order to adjust the 3D-image brightness values. In addition, the photographic principle is used in this study to measure metering values by capturing 2D and 3D images on television screens. By analyzing these images with statistical product and service solutions (SPSS software, the image brightness values can be estimated using the statistical regression model, which can also indicate the impact of various environmental factors or hardware on the image brightness. In analysis of the experimental results, comparison of the image brightness between 2D and 3D images indicates 60.8% degradation in the 3D image brightness amplitude. The experimental values, from 52.4% to 69.2%, are within the 95% confidence interval

  16. Who benefits from gm crops? Feeding the biotech giants, not the world's poor

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Villar, J.; Freese, B.; Holder, H.; Chandrasekaran, K.; Rodriguez, L.

    2009-02-15

    The biotechnology industry has aggressively touted GM as a solution to hunger and the global food crisis. Their arguments have been accepted by many politicians. This Friends of the Earth International (FoEI) report looks behind the spin and exposes the reasons why GM crops cannot, and are unlikely to ever, contribute to poverty reduction, global food security or sustainable farming (authors' abstract)

  17. Development of a dry linear compressor for GM and pulse tube cryocoolers

    Science.gov (United States)

    Hoehne, J.

    2015-12-01

    Pressure Wave Systems GmbH has developed a dry compressor for GM and pulse tube cryocoolers. The concept is based on hydraulically driven metal bellows in which the Helium working gas is compressed. The system is operated in the region of 1 kW of electrical input power and has been successfully tested with a SHI RDK-101D GM cryocooler cold head. Set-up, performance and reliability of the compressor system will be discussed.

  18. Development of a dry linear compressor for GM and pulse tube cryocoolers

    CERN Document Server

    Höhne, Jens

    2015-01-01

    Pressure Wave Systems GmbH has developed a dry compressor for GM and pulse tube cryocoolers. The concept is based on hydraulically driven metal bellows in which the Helium working gas is compressed. The system is operated in the region of 1 kW of electrical input power and has been successfully tested with a SHI RDK-101D GM cryocooler cold head. Set-up, performance and reliability of the compressor system will be discussed.

  19. Irish public perceptions and attitudes to modern biotechnology: an overview with a focus on GM foods.

    Science.gov (United States)

    Morris, S H; Adley, C C

    2001-02-01

    This article summarizes the current situation pertaining to modern biotechnology in Ireland, with a particular focus on genetically modified (GM) crops. It briefly examines some important results of the major national surveys carried out in Ireland since 1989, highlights the recent upsurge in media (newspaper) coverage of GM related stories in three Irish opinion leader publications and it allows for an insight into the Irish public's relationship with modern biotechnology.

  20. The current state of GMO governance: are we ready for GM animals?

    Science.gov (United States)

    Vàzquez-Salat, Núria; Salter, Brian; Smets, Greet; Houdebine, Louis-Marie

    2012-01-01

    Given the history of GMO conflict and debate, the GM animal future is dependent on the response of the regulatory landscape and its associated range of interest groups at national, regional and international levels. Focusing on the EU and the USA, this article examines the likely form of that multi-level response, the increased role of cultural values, the contribution of new and existing interest groups and the consequent implications for the commercialization of both green and red GM animal biotechnology.

  1. GM-CSF Differentially Regulates Eosinophil and Neutrophil Adhesive Interactions with Vascular Endothelium in Vivo

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    Nooshin Sheikh Bahaie

    2010-12-01

    Full Text Available Allergic airway inflammation is characterized by elaboration of cytokines and chemokines leading to recruitment of inflammatory leukocytes, predominantly eosinophils, to the airways. Granulocyte macrophage colony stimulating factor (GM-CSF is generated in the lungs of human subjects with asthma in response to allergen challenge and is necessary for the development of allergen-induced bronchial eosinophilia in mice. The effect of GM-CSF on human eosinophil and neutrophil interactions with the vascular endothelium under conditions of blood flow was investigated in post-capillary venules of the rabbit mesentery by intravital microscopy.While GM-CSF significantly reduced the rolling fraction of neutrophils in vivo and induced consistent shedding of neutrophil L-selectin in vitro, its effect on eosinophil rolling was variable. Eosinophils from 57% of the donors demonstrated inhibition of rolling, while eosinophils from the remaining 43% of donors demonstrated no inhibition or increased rolling. The variable effect of GM-CSF on inhibition of eosinophil rolling was associated with variable shedding of L-selectin in vitro. In contrast to the differential effect of GM-CSF on neutrophils versus eosinophils, stimulation with phorbol myristate acetate demonstrated a similar degree of inhibition of rolling and L-selectin shedding by neutrophils and eosinophils suggesting that there was no defect in L-selectin shedding in the eosinophil donors who did not respond to GM-CSF. Overall, these studies demonstrate that GM-CSF consistently inhibits interaction of neutrophils with endothelium in vivo, whereas its effect on eosinophil-endothelial interactions is variable. GM-CSF may thus be one factor accounting for the varying percentage of eosinophils and neutrophils recruited to sites of allergic inflammation in different individuals.

  2. Silencing of GM3 synthase suppresses lung metastasis of murine breast cancer cells

    OpenAIRE

    Gu, Yuchao; ZHANG, JUNHUA; Mi, Wenyi; Yang, Jing; Han, Feng; Lu, Xinzhi; Yu, Wengong

    2008-01-01

    Background Gangliosides are sialic acid containing glycosphingolipids that are ubiquitously distributed on vertebrate plasma membranes. GM3, a precursor for most of the more complex ganglioside species, is synthesized by GM3 synthase. Although total ganglioside levels are significantly higher in breast tumor tissue than in normal mammary tissue, the roles played by gangliosides in breast cancer formation and metastasis are not clear. Methods To investigate the roles of gangliosides in breast ...

  3. Market Power of the Japanese Non-GM Soybean Import Market: The U.S. Exporters VS. Japanese Importers

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    Koichi Yamaura

    2011-12-01

    Full Text Available Genetically modified (GM soybean acreage has rapidly increased in the world in the past decade and globally the majority of countries now use GM soybeans to produce oil and meal for livestock and human consumption. Japan, however, uses only Non-GM soybeans as widely recognized high quality goods in vertically differentiated import soybeans in Japan, for direct human consumption of which more than 80% are imported from the U.S., Canada, and China. This research used the inverse residual demand model to estimate a U.S.-Japan partial equilibrium trade model to test the existence of market power in the Japanese Non-GM soybean import market. The U.S.-Japan partial equilibrium trade model incorporated the U.S. residual Non-GM soybean supply for Japan, the Japanese residual demand for U.S. Non-GM soybeans, and the equilibrium condition, where the U.S. residual Non-GM soybean supply equals the Japanese residual Non-GM soybean demand. Monthly data from January 2003 to December 2007 were used for the analysis. Empirical results indicated that U.S. Non-GM soybean exporters have stronger market power than Japanese Non-GM soybean importers. The results are different from other countries empirical studies and indicate that Japanese consumers are willing to pay higher prices for soybeans, tofu, natto, miso, and other all soy food products using Non-GM soybeans.

  4. Market Power of The Japanese Non-GM Soybean Import Market: The U.S. Exporters vs. Japanese Importers

    Directory of Open Access Journals (Sweden)

    Koichi Yamaura

    2011-12-01

    Full Text Available Genetically modified (GM soybean acreage has rapidly increased in the world in the past decade and globally the majority of countries now use GM soybeans to produce oil and meal for livestock and human consumption. Japan,however, uses only Non-GM soybeans as widely recognized high quality goods in vertically differentiated import soybeans in Japan, for direct human consumption of which more than 80% are imported from the U.S., Canada, and China. This research used the inverse residual demand model to estimate a U.S.-Japan partial equilibrium trade model to test the existence of market power in the Japanese Non-GM soybean import market. The U.S.-Japan partial equilibrium trade model incorporated the U.S. residual Non-GM soybeansupply for Japan, the Japanese residual demand for U.S. Non-GM soybeans, and the equilibrium condition, where the U.S. residual Non-GM soybean supply equals the Japanese residual Non-GM soybean demand. Monthly data from January 2003 to December 2007 were used for the analysis. Empirical results indicated that U.S. Non-GM soybean exporters have stronger market power than Japanese Non-GM soybean importers. The results are different from other countries empirical studies and indicate that Japanese consumers are willing to pay higher prices for soybeans, tofu, natto, miso, and other all soy food products using Non-GM soybeans.

  5. Comparative approaches on the shops metallurgists for the modern viniculture. The pioneer Antonio Baldé, Gil Miret and Carlos Berri in Mendoza Aproximaciones comparativas sobre los talleres metalúrgicos para la vitivinicultura moderna. Los pioneros Antonio Baldé, Gil Miret y Carlos Berri en Mendoza

    Directory of Open Access Journals (Sweden)

    Eduardo Pérez Romagnoli

    2007-01-01

    Full Text Available This paper proposes a comparison among the main characteristics of the two shops pioneer metallurgists in the production of instruments and equipment for wineries and industrial stills, in the beginnings of the modern viniculture in Mendoza . The Catalan partners Antonio Baldé and Gil Miret began in 1885 and the Italian Carlos Berri in 1888. A general panorama is presented on the equipment of the shops and the objects produced, the characteristics of the labor, the formation in metallurgy of the proprietors, the insert of the two firms in the region, a reference to other economic activities developed by the managers and some complementary questions.Este trabajo propone una comparación entre las características principales de los dos talleres metalúrgicos pioneros en la producción de instrumentos y equipamiento para bodegas y destilerías industriales, en los comienzos de la vitivinicultura moderna en Mendoza. Los socios catalanes Antonio Baldé y Gil Miret comenzaron en 1885 y el italiano Carlos Berri en 1888. Se presenta un panorama general sobre el equipamiento de los talleres y los objetos que producían, las características de la mano de obra, la formación metalúrgica de los propietarios, la inserción de las dos firmas en la región, una referencia a otras actividades económicas desarrolladas por los empresarios y algunas cuestiones complementarias.

  6. Don Juan de Palafox y Mendoza, promotor del libre acceso a la información en el siglo XVII novo-hispano Don Juan de Palafox y Mendoza promoter of free access to information in the eighteenth century in New Spain

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    Rosa María Fernández de Zamora

    2011-08-01

    Full Text Available Don Juan de Palafox y Mendoza, arzobispo y virrey de la Nueva España y obispo de Puebla en el siglo XVII, ha sido motivo de numerosos estudios, pero lo que se desea resaltar en este escrito es su labor como fundador de la primera biblioteca pública de México y del continente americano, misma que hoy conocemos como Biblioteca Palafoxiana, y como promotor del libre acceso a la información. En el siglo XVIII, el obispo de Puebla, Francisco Fabián y Fuero, seguidor de las ideas de Palafox, enriqueció y embelleció la biblioteca y continuó con el espíritu de apertura propuesto por el fundador. También se menciona el reconocimiento que el ilustre jesuita Clavijero hizo de las obras de Palafox.Don Juan de Palafox y Mendoza, Viceroy and Archbishop of New Spain, and Bishop of Puebla in the XVII century, has been studied by many specialists. However, the purpose of this paper is to highlight his role as founder of the first public library in Mexico and in the American Continent and promoter of free acces to information. In the XVIII Century Francisco Fabián y Fuero, Bishop of Puebla, enriched and embellished the Palafoxiana library and continued the policies of its founder. Attention is also drawn to the recognition that the renowned Jesuit Clavijero made of the work of Palafox.

  7. Tecnología cerámica y estrategias de movilidad entre cazadores-recolectores de altura: El caso del sitio Valle Hermoso 1 (Malargüe, Mendoza Ceramic technology and mobility strategies among high altitude hunter-gatherers: the case of Valle Hermoso 1 site, Malargue, Mendoza

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    Nuria Sugrañes

    2011-12-01

    Full Text Available En este trabajo presentamos los resultados del análisis cerámico de los tiestos recuperados en el sitio Valle Hermoso 1 (Malargüe, Mendoza. A través de estos se discuten las estrategias de movilidad de cazadores-recolectores con cerámica en ambientes de altura. El sitio muestra una ocupación inicial de ca. 1900 años AP, y los resultados obtenidos sugieren la presencia de dos conjuntos con materiales cerámicos diversos, que corresponderían a grupos con una alta movilidad con reocupación estacional del valle.This paper draws on the results of analyses of ceramics recovered from the Valle Hermoso 1 site, Malargüe, Mendoza. The mobility strategies of hunter-gatherers with pottery in a high altitude environment are discussed on the basis of these data. The site was initially occupied ca. 1900 BP, and evidence suggests that there are two assemblages with different ceramic materials associated with highly mobile groups that reoccupied the valley seasonally.

  8. GM trees with increased resistance to herbivores: trait efficiency and their potential to promote tree growth.

    Science.gov (United States)

    Hjältén, Joakim; Axelsson, E Petter

    2015-01-01

    Climate change, as well as a more intensive forestry, is expected to increase the risk of damage by pests and pathogens on trees, which can already be a severe problem in tree plantations. Recent development of biotechnology theoretically allows for resistance enhancement that could help reduce these risks but we still lack a comprehensive understanding of benefits and tradeoffs with pest resistant GM (genetically modified) trees. We synthesized the current knowledge on the effectiveness of GM forest trees with increased resistance to herbivores. There is ample evidence that induction of exogenous Bacillus thuringiensis genes reduce performance of target pests whereas upregulation of endogenous resistance traits e.g., phenolics, generates variable results. Our review identified very few studies estimating the realized benefits in tree growth of GM trees in the field. This is concerning as the realized benefit with insect resistant GM plants seems to be context-dependent and likely manifested only if herbivore pressure is sufficiently high. Future studies of secondary pest species and resistance evolution in pest to GM trees should be prioritized. But most importantly we need more long-term field tests to evaluate the benefits and risks with pest resistant GM trees.

  9. GM-CSF GENE OR B7-1 GENE MODIFIED MURINE EL-4 CELLS VACCINE

    Institute of Scientific and Technical Information of China (English)

    张清媛; 李殿俊; 王志华

    2001-01-01

    Objective: To study the vaccine potency of gene-modified tumor cells. Methods: The EL-4 lymphoma was transduced with recombinant retrovirus containing the murine GM-CSF gene or B7-1 gene. The effect of gene transduction on antitumor immunity was investigated. Results: Flow cytometry analysis showed that expression of their surface marker between wild-type EL-4 cells and gene transduced tumor cells was the same except for CD80 positive in B7-1 gene transduced cells. GM-CSF gene or B7-1 gene transduced EL-4 cells resulted in remarkable loss of tumorigenicity in syngenetic mice. The systemic protective immunity was induced against the challenge with EL-4/wt cells. Therapeutic vaccine with EL-4/GM-CSF or EL/7-1 cells could retard the growth of established early-stage EL-4/wt tumor significantly, but not retard the growth of late-stage EL-4/wt tumor. Irradiated GM-CSF gene transduced EL-4 cells showed strong vaccine effect against EL-4 cell challenge, but irradiated B7-1 gene transduced EL-4 cells showed weak vaccine effect. Remarkable cooperative antitumor effect against EL-4 cell challenge was observed when both irradiated EL-4/GM-CSF and EL-4/B7-1 were inoculated together. Conclusion: GM-CSF gene or B7-1 gene transduced combination of the two kinds of vaccine may have potential application value in human cancer treatment.

  10. Incorporating the use of GM-CSF in the treatment of chronic lymphocytic leukemia.

    Science.gov (United States)

    Ferrajoli, Alessandra

    2009-03-01

    We evaluated the clinical activity of GM-CSF in combination with standard dose rituximab in patients with chronic lymphocytic leukemia (CLL). The rationale for exploring this combination is provided by the ability of GM-CSF to increase surface expression of CD20 in CLL cells and potentially render them a better target for rituximab. GM-CSF also enhances antibody-dependent cellular cytotoxicity against CLL cells. The combination of GM-CSF and rituximab was evaluated as initial treatment in elderly patients with indication for treatment and in patients at high risk for progression identified by elevated beta(2) microglobulin. This combination was also evaluated in patients with recurrent CLL. On the basis of the results of 118 patients, we observed an overall response rate of 65 and 9% complete remission and these results compare favourably with the results obtained with rituximab single agent. This combination was well tolerated with the most common toxicity consisting in mild GM-CSF injection site erythema. On the basis of this experience, we are currently evaluating the use of GM-CSF in combination with the chemoimmunotherapy regimen fludarabine, cyclophosphamide and rituximab.

  11. Health effect of agricultural pesticide use in China: implications for the development of GM crops

    Science.gov (United States)

    Zhang, Chao; Hu, Ruifa; Huang, Jikun; Huang, Xusheng; Shi, Guanming; Li, Yifan; Yin, Yanhong; Chen, Zhaohui

    2016-01-01

    It is notable that the adoption of GM glyphosate-tolerant crops increases glyphosate use but reduces non-glyphosate herbicide use; and adoption of GM insect-resistant crops significantly reduces insecticide use. While the health hazard of pesticide use has been well documented, little literature evaluates the health effects of different pesticides related to GM crops in an integrated framework. This study aims to associate the uses of different pesticides related to GM crops with the blood chemistry panel and peripheral nerve conduction of Chinese farmers. Pesticides used by farmers were recorded and classified as glyphosate, non-glyphosate herbicides, chemical lepidopteran insecticides, biological lepidopteran insecticides, non-lepidopteran insecticides and fungicides. The multivariate regression results show that none of the examined 35 health indicators was associated with glyphosate use, while the use of non-glyphosate herbicides was likely to induce renal dysfunction and decrease of serum folic acid. The use of chemical lepidopteran insecticides might be associated with hepatic dysfunction, serum glucose elevation, inflammation and even severe nerve damage. In this context, if GM crops are adopted, the alterations in pesticide use may benefit farmer health in China and globe, which has positive implications for the development of GM crops. PMID:27721390

  12. MafB antagonizes phenotypic alteration induced by GM-CSF in microglia.

    Science.gov (United States)

    Koshida, Ryusuke; Oishi, Hisashi; Hamada, Michito; Takahashi, Satoru

    Microglia are tissue-resident macrophages which are distributed throughout the central nervous system (CNS). Recent studies suggest that microglia are a unique myeloid population distinct from peripheral macrophages in terms of origin and gene expression signature. Granulocyte-macrophage colony-stimulating factor (GM-CSF), a pleiotropic cytokine regulating myeloid development, has been shown to stimulate proliferation and alter phenotype of microglia in vitro. However, how its signaling is modulated in microglia is poorly characterized. MafB, a bZip transcriptional factor, is highly expressed in monocyte-macrophage lineage cells including microglia, although its role in microglia is largely unknown. We investigated the crosstalk between GM-CSF signaling and MafB by analyzing primary microglia. We found that Mafb-deficient microglia grew more rapidly than wild-type microglia in response to GM-CSF. Moreover, the expression of genes associated with microglial differentiation was more downregulated in Mafb-deficient microglia cultured with GM-CSF. Notably, such differences between the genotypes were not observed in the presence of M-CSF. In addition, we found that Mafb-deficient microglia cultured with GM-CSF barely extended their membrane protrusions, probably due to abnormal activation of RhoA, a key regulator of cytoskeletal remodeling. Altogether, our study reveals that MafB is a negative regulator of GM-CSF signaling in microglia. These findings could provide new insight into the modulation of cytokine signaling by transcription factors in microglia.

  13. The soybean GmSNAP18 gene underlies two types of resistance to soybean cyst nematode

    Science.gov (United States)

    Liu, Shiming; Kandoth, Pramod K.; Lakhssassi, Naoufal; Kang, Jingwen; Colantonio, Vincent; Heinz, Robert; Yeckel, Greg; Zhou, Zhou; Bekal, Sadia; Dapprich, Johannes; Rotter, Bjorn; Cianzio, Silvia; Mitchum, Melissa G.; Meksem, Khalid

    2017-01-01

    Two types of resistant soybean (Glycine max (L.) Merr.) sources are widely used against soybean cyst nematode (SCN, Heterodera glycines Ichinohe). These include Peking-type soybean, whose resistance requires both the rhg1-a and Rhg4 alleles, and PI 88788-type soybean, whose resistance requires only the rhg1-b allele. Multiple copy number of PI 88788-type GmSNAP18, GmAAT, and GmWI12 in one genomic segment simultaneously contribute to rhg1-b resistance. Using an integrated set of genetic and genomic approaches, we demonstrate that the rhg1-a Peking-type GmSNAP18 is sufficient for resistance to SCN in combination with Rhg4. The two SNAPs (soluble NSF attachment proteins) differ by only five amino acids. Our findings suggest that Peking-type GmSNAP18 is performing a different role in SCN resistance than PI 88788-type GmSNAP18. As such, this is an example of a pathogen resistance gene that has evolved to underlie two types of resistance, yet ensure the same function within a single plant species. PMID:28345654

  14. Overexpression of soybean isoflavone reductase (GmIFR enhances resistance to Phytophthora sojae in soybean

    Directory of Open Access Journals (Sweden)

    Qun eCheng

    2015-11-01

    Full Text Available Isoflavone reductase (IFR is an enzyme involved in the biosynthetic pathway of isoflavonoid phytoalexin in plants. IFRs are unique to the plant kingdom and are considered to have crucial roles in plant response to various biotic and abiotic environmental stresses. Here, we report the characterization of a novel member of the soybean isoflavone reductase gene family GmIFR. The cDNA of GmIFR was 1199 bp containing a 939 bp open reading frame encoding a polypeptide of 312 amino acids. Sequence analysis suggested that GmIFR contained a NAD(P domain of 107 amino acids. Overexpression of GmIFR transgenic soybean exhibited enhanced resistance to Phytophthora sojae. Following stress treatments, GmIFR was significantly induced by P. sojae, ethephon (ET, abscisic acid (ABA, salicylic acid (SA. It is located in the cytoplasmic when transiently expressed in Arabidopsis protoplasts. The daidzein levels reduced greatly for the seeds of transgenic plants, while levels of genistein and glycitein had little change compared to that of control plants. Furthermore, we also found that the reactive oxygen species (ROS content of transgenic soybean plants was significantly lower than that of control plants, suggesting an important role of GmIFR might function as an antioxidant to reduce ROS in soybean.

  15. Acquirement and characterization of a carotenoid mutant (GM309) of Rhodobacter sphaeroides 601

    Institute of Scientific and Technical Information of China (English)

    LIU Yuan; ZHANG Wei; WU Yongqiang; XU Chunhe

    2004-01-01

    A green mutant was obtained among the chemically induced mutants of Rhodobacter sphaeroides 601 (RS601) and named GM309. A blue shift of 20 nm of the carotenoid absorption spectrum was found in the light-harvesting complex II (LH2) of GM309. Different from LH2 of RS601, it was found that the carotenoids in GM309-LH2 changed to be neurosporene by mutation. Neurosporene lacks a conjugate double bond, compared with the spheroidene in RS601-LH2 which has ten conjugate double bonds. As shown by absorption and circular dichroism spectroscopy, the overall structure of GM309-LH2 is little affected by this change. From fluorescence emission spectra, it is found that GM309-LH2 can transfer energy from carotenoids to Bchl-B850 without any change in efficiency. But the efficiency of energy transfer from B800 to B850 in GM309-LH2 is decreased to be 42% of that of the native. This work would provide a novel method to investigate the mechanism of excitation energy transfer in LH2.

  16. Social Impacts of GM Crops in Agriculture: A Systematic Literature Review

    Directory of Open Access Journals (Sweden)

    Klara Fischer

    2015-07-01

    Full Text Available It has recently been argued that the fragmented knowledge on the social impacts of genetically modified (GM crops is contributing to the polarised debate on the matter. This paper addresses this issue by systematically reviewing 99 peer-reviewed journal articles published since 2004 on the social impacts of GM crops in agriculture; summarising current knowledge, and identifying research gaps. Economic impact studies currently dominate the literature and mainly report that GM crops provide economic benefits for farmers. Other social impacts are less well studied, but present a more complex picture. Studies on access to and benefits of GM crops show that these vary significantly depending on the political and regulatory setting. Substantial evidence indicates that intellectual property rights (IPR and the private industry’s dominance limit the access and utility of available GM crops to many farmers. Wellbeing is frequently discussed in the literature, but rarely investigated empirically. Existing evidence is contradictory and inconclusive. Impact studies from the Global North are virtually non-existent. Moreover, two-thirds of publications are based on previously published empirical evidence, indicating a need for new empirical investigations into the social impacts of GM crops in agriculture.

  17. Larger Planet Radii Inferred from Stellar "Flicker" Brightness Variations of Bright Planet Host Stars

    CERN Document Server

    Bastien, Fabienne A; Pepper, Joshua

    2014-01-01

    Most extrasolar planets have been detected by their influence on their parent star, typically either gravitationally (the Doppler method) or by the small dip in brightness as the planet blocks a portion of the star (the transit method). Therefore, the accuracy with which we know the masses and radii of extrasolar planets depends directly on how well we know those of the stars, the latter usually determined from the measured stellar surface gravity, logg. Recent work has demonstrated that the short-timescale brightness variations ("flicker") of stars can be used to measure logg to a high accuracy of ~0.1-0.2 dex (Bastien et al. 2013). Here, we use flicker measurements of 289 bright (Kepmag<13) candidate planet-hosting stars with Teff=4500-6650 K to re-assess the stellar parameters and determine the resulting impact on derived planet properties. This re-assessment reveals that for the brightest planet-host stars, an astrophysical bias exists that contaminates the stellar sample with evolved stars: nearly 50%...

  18. Geología de la región del Cerro Guanaquero, Río Diamante, Mendoza

    Directory of Open Access Journals (Sweden)

    Federico Fuentes

    2008-03-01

    Full Text Available El estudio realizado presenta nuevos datos sobre un sector poco conocido de la Cordillera Principal de Mendoza, en la alta cuenca del río Diamante en las adyacencias del cerro Guanaquero, y los primeros datos geocronológicos de sus rocas volcánicas. Las unidades geológicas presentes en el área se dividen en cuatro grupos principales: secuencias sedimentarias mesozoicas marinas y continentales intensamente plegadas y falladas; intrusivos y volcanitas intermedias de edad neógena; rocas volcánicas pliocenas a recientes de composición intermedia a básica, y depósitos cuaternarios inconsolidados. El cerro Guanaquero, un estratovolcán pliocuaternario intensamente erosionado por glaciares pleistocenos, con sus 4.841 metros es el rasgo orográfico más prominente. Está constituido esencialmente por andesitas grises porfíricas, piroxénicas a biotíticas. Intercaladas con las coladas andesíticas se presentan depósitos piroclásticos, aglomerados volcánicos, ignimbritas y basaltos. La datación de una andesita por el método K-Ar en roca total arrojó una edad de 1,4 ± 0,1 Ma. La deformación ándica comenzó en forma de una faja plegada y corrida de piel fina, con pliegues por despegue en el sector occidental y por propagación de falla en el oriental. La compresión al oeste de los 69º47´O terminó por invertir la fallas normales del rift mesozoico. A lo largo de este meridiano se encuentra la falla más importante de la región, la que se ha correlacionado con la falla Malargüe, bien desarrollada en latitudes más australes. Esta falla limita la faja plegada y corrida del Aconcagua, de naturaleza epidérmica, y la faja plegada y corrida de Malargüe, controlada por la inversión tectónica del basamento. El volcanismo fue muy intenso en el Plioceno y el Cuaternario, correspondiendo a un período de empinamiento de la placa oceánica subducida, en el que la región ha sido levantada pasivamente. La alta resistencia a la erosión de

  19. Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF activity.

    Directory of Open Access Journals (Sweden)

    Gözde Isik

    Full Text Available HIV-1 acquisition can be prevented by broadly neutralizing antibodies (BrNAbs that target the envelope glycoprotein complex (Env. An ideal vaccine should therefore be able to induce BrNAbs that can provide immunity over a prolonged period of time, but the low intrinsic immunogenicity of HIV-1 Env makes the elicitation of such BrNAbs challenging. Co-stimulatory molecules can increase the immunogenicity of Env and we have engineered a soluble chimeric Env trimer with an embedded granulocyte-macrophage colony-stimulating factor (GM-CSF domain. This chimeric molecule induced enhanced B and helper T cell responses in mice compared to Env without GM-CSF. We studied whether we could optimize the activity of the embedded GM-CSF as well as the antigenic structure of the Env component of the chimeric molecule. We assessed the effect of truncating GM-CSF, removing glycosylation-sites in GM-CSF, and adjusting the linker length between GM-CSF and Env. One of our designed Env(GM-CSF chimeras improved GM-CSF-dependent cell proliferation by 6-fold, reaching the same activity as soluble recombinant GM-CSF. In addition, we incorporated GM-CSF into a cleavable Env trimer and found that insertion of GM-CSF did not compromise Env cleavage, while Env cleavage did not compromise GM-CSF activity. Importantly, these optimized Env(GM-CSF proteins were able to differentiate human monocytes into cells with a macrophage-like phenotype. Chimeric Env(GM-CSF should be useful for improving humoral immunity against HIV-1 and these studies should inform the design of other chimeric proteins.

  20. High Brightness Neutron Source for Radiography

    Energy Technology Data Exchange (ETDEWEB)

    Cremer, J. T.; Piestrup, Melvin, A.; Gary, Charles, K.; Harris, Jack, L. Williams, David, J.; Jones, Glenn, E.; Vainionpaa, J. , H.; Fuller, Michael, J.; Rothbart, George, H.; Kwan, J., W.; Ludewigt, B., A.; Gough, R.., A..; Reijonen, Jani; Leung, Ka-Ngo

    2008-12-08

    This research and development program was designed to improve nondestructive evaluation of large mechanical objects by providing both fast and thermal neutron sources for radiography. Neutron radiography permits inspection inside objects that x-rays cannot penetrate and permits imaging of corrosion and cracks in low-density materials. Discovering of fatigue cracks and corrosion in piping without the necessity of insulation removal is possible. Neutron radiography sources can provide for the nondestructive testing interests of commercial and military aircraft, public utilities and petrochemical organizations. Three neutron prototype neutron generators were designed and fabricated based on original research done at the Lawrence Berkeley National Laboratory (LBNL). The research and development of these generators was successfully continued by LBNL and Adelphi Technology Inc. under this STTR. The original design goals of high neutron yield and generator robustness have been achieved, using new technology developed under this grant. In one prototype generator, the fast neutron yield and brightness was roughly 10 times larger than previously marketed neutron generators using the same deuterium-deuterium reaction. In another generator, we integrate a moderator with a fast neutron source, resulting in a high brightness thermal neutron generator. The moderator acts as both conventional moderator and mechanical and electrical support structure for the generator and effectively mimics a nuclear reactor. In addition to the new prototype generators, an entirely new plasma ion source for neutron production was developed. First developed by LBNL, this source uses a spiral antenna to more efficiently couple the RF radiation into the plasma, reducing the required gas pressure so that the generator head can be completely sealed, permitting the possible use of tritium gas. This also permits the generator to use the deuterium-tritium reaction to produce 14-MeV neutrons with increases

  1. New Insights on Non-Enzymatic Oxidation of Ganglioside GM1 Using Mass Spectrometry

    Science.gov (United States)

    Couto, Daniela; Melo, Tânia; Maciel, Elisabete; Campos, Ana; Alves, Eliana; Guedes, Sofia; Domingues, M. Rosário M.; Domingues, Pedro

    2016-12-01

    Gangliosides are acidic glycosphingolipids that are present in cell membranes and lipid raft domains, being particularly abundant in central nervous systems. They participate in modulating cell membrane properties, cell-cell recognition, cell regulation, and signaling. Disturbance in ganglioside metabolism has been correlated with the development of diseases, such as neurodegenerative diseases, and in inflammation. Both conditions are associated with an increased production of reactive oxidation species (ROS) that can induce changes in the structure of biomolecules, including lipids, leading to the loss or modification of their function. Oxidized phospholipids are usually involved in chronic diseases and inflammation. However, knowledge regarding oxidation of gangliosides is scarce. In order to evaluate the effect of ROS in gangliosides, an in vitro biomimetic model system was used to study the susceptibility of GM1 (Neu5Ac α2-3(Gal β1-3GalNAc β1-4)Gal β1-4Glc β1Cer) to undergo oxidative modifications. Oxidation of GM1 under Fenton reaction conditions was monitored using high resolution electrospray ionization-mass spectrometry (ESI-MS) and tandem mass spectrometry (ESI-MS/MS). Upon oxidation, GM1 underwent oxidative cleavages in the carbohydrate chain, leading to the formation of other gangliosides GM2 (GalNAcβ1-4Gal(Neu5Acα2-3)1-4Glcβ1Cer), GM3 (Neu5Acα2-3Galβ1-4Glcβ1Cer), asialo-GM1 (Gal β1-3GalNAc β1-4Gal β1-4Glc β1Cer), asialo-GM2 (GalNAc β1-4Gal β1-4Glc β1Cer), of the small glycolipids lactosylceramide (LacCer), glucosylceramide (GlcCer), and of ceramide (Cer). In addition, oxygenated GM1 and GM2 (as keto and hydroxy derivatives), glycans, oxidized glycans, and oxidized ceramides were also identified. Nonenzymatic oxidation of GM1 under oxidative stress contributes to the generation of other gangliosides that may participate in the imbalance of gangliosides metabolism in vivo, through uncontrolled enzymatic pathways and, consequently, play

  2. New Insights on Non-Enzymatic Oxidation of Ganglioside GM1 Using Mass Spectrometry

    Science.gov (United States)

    Couto, Daniela; Melo, Tânia; Maciel, Elisabete; Campos, Ana; Alves, Eliana; Guedes, Sofia; Domingues, M. Rosário M.; Domingues, Pedro

    2016-08-01

    Gangliosides are acidic glycosphingolipids that are present in cell membranes and lipid raft domains, being particularly abundant in central nervous systems. They participate in modulating cell membrane properties, cell-cell recognition, cell regulation, and signaling. Disturbance in ganglioside metabolism has been correlated with the development of diseases, such as neurodegenerative diseases, and in inflammation. Both conditions are associated with an increased production of reactive oxidation species (ROS) that can induce changes in the structure of biomolecules, including lipids, leading to the loss or modification of their function. Oxidized phospholipids are usually involved in chronic diseases and inflammation. However, knowledge regarding oxidation of gangliosides is scarce. In order to evaluate the effect of ROS in gangliosides, an in vitro biomimetic model system was used to study the susceptibility of GM1 (Neu5Acα2-3(Galβ1-3GalNAcβ1-4)Galβ1-4Glcβ1Cer) to undergo oxidative modifications. Oxidation of GM1 under Fenton reaction conditions was monitored using high resolution electrospray ionization-mass spectrometry (ESI-MS) and tandem mass spectrometry (ESI-MS/MS). Upon oxidation, GM1 underwent oxidative cleavages in the carbohydrate chain, leading to the formation of other gangliosides GM2 (GalNAcβ1-4Gal(Neu5Acα2-3)1-4Glcβ1Cer), GM3 (Neu5Acα2-3Galβ1-4Glcβ1Cer), asialo-GM1 (Galβ1-3GalNAcβ1-4Galβ1-4Glcβ1Cer), asialo-GM2 (GalNAcβ1-4Galβ1-4Glcβ1Cer), of the small glycolipids lactosylceramide (LacCer), glucosylceramide (GlcCer), and of ceramide (Cer). In addition, oxygenated GM1 and GM2 (as keto and hydroxy derivatives), glycans, oxidized glycans, and oxidized ceramides were also identified. Nonenzymatic oxidation of GM1 under oxidative stress contributes to the generation of other gangliosides that may participate in the imbalance of gangliosides metabolism in vivo, through uncontrolled enzymatic pathways and, consequently, play some role in

  3. Modular Zero Energy. BrightBuilt Home

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, Robb [Consortium for Advanced Residential Buildings (CARB), Norwalk, CT (United States). Steven Winters Associates, Inc.; Butterfield, Karla [Consortium for Advanced Residential Buildings (CARB), Norwalk, CT (United States). Steven Winters Associates, Inc.

    2016-03-01

    Kaplan Thompson Architects (KTA) has specialized in sustainable, energy-efficient buildings, and they have designed several custom, zero-energy homes in New England. These zero-energy projects have generally been high-end, custom homes with budgets that could accommodate advanced energy systems. In an attempt to make zero energy homes more affordable and accessible to a larger demographic, KTA explored modular construction as way to provide high-quality homes at lower costs. In the mid-2013, KTA formalized this concept when they launched BrightBuilt Home (BBH). The BBH mission is to offer a line of architect-designed, high-performance homes that are priced to offer substantial savings off the lifetime cost of a typical home and can be delivered in less time. For the past two years, CARB has worked with BBH and Keiser Homes (the primary modular manufacturer for BBH) to discuss challenges related to wall systems, HVAC, and quality control. In Spring of 2014, CARB and BBH began looking in detail on a home to be built in Lincolnville, ME by Black Bros. Builders. This report details the solution package specified for this modular plan and the challenges that arose during the project.

  4. GOMOS bright limb ozone data set

    Directory of Open Access Journals (Sweden)

    S. Tukiainen

    2015-01-01

    Full Text Available We have created a daytime ozone profile data set from the measurements of the Global Ozone Monitoring by Occultation of Stars (GOMOS instrument on board the Envisat satellite. This so-called GOMOS bright limb (GBL data set contains ~ 358 000 stratospheric daytime ozone profiles measured by GOMOS in 2002–2012. The GBL data set complements the widely used GOMOS night-time data based on stellar occultation measurements. The GBL data set is based on the GOMOS daytime occultations but instead of the transmitted star light, we use limb scattered solar light. The ozone profiles retrieved from these radiance spectra cover 18–60 km tangent height range and have approximately 2–3 km vertical resolution. We show that these profiles are generally in better than 10% agreement with the NDACC (Network for the Detection of Atmospheric Composition Change ozone sounding profiles and with the GOMOS night-time, MLS (Microwave Limb Sounder, and OSIRIS (Optical Spectrograph, and InfraRed Imaging System satellite measurements. However, there is a 10–13% negative bias at 40 km tangent height and a 10–50% positive bias at 50 km when the solar zenith angle > 75°. These biases are most likely caused by stray light which is difficult to characterize and remove entirely from the measured spectra. Nevertheless, the GBL data set approximately doubles the amount of useful GOMOS ozone profiles and improves coverage of the summer pole.

  5. Mechanical electrodeposition of bright nanocrystalline nickel

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new mechanical electrodeposition technology was proposed, and nanocrystalline nickel deposit with bright and smooth surface was prepared in the bath without any additive agents. Unlike traditional methods, the novel technology employed dynamical hard particles to continuously polish the cathode surface and disturb the nearby solution during electrodepositing. Experimental results showed that the polishing effect of hard particles can effectively prevent the hydrogen bubbles and impurities from adhering on the deposit surface and avoid the production of pits, pinholes and nodules. Furthermore, comparing with the deposit prepared by traditional methods, the one prepared by the novel technology was substantially refined with grain size ranging from 30 to 80 nm. Every diffraction peak’s intensity of the deposit was reduced, the preferential orientation degree of (200) decreased and those of (111) and (220) increased. The microhardness notably increased. The magnetic properties were also changed with decreased saturation magnetization and increased coercive force. It was also found that variation of current density and cathode rotational speed could affect the structure and properties of the nickel deposits prepared by this technology.

  6. The Los Alamos high-brightness photoinjector

    Energy Technology Data Exchange (ETDEWEB)

    O' Shea, P.G.

    1991-01-01

    For a number of years Los Alamos National Laboratory has been developing photocathode RF guns for high-brightness electron beam applications such as free-electron lasers (FELs). Previously thermionic high-voltage guns have been the source of choice for the electron accelerators used to drive FELs. The performance of such FELs is severely limited by the emittance growth produced by the subharmonic bunching process and also by the low peak current of the source. In a photoinjector, a laser driven photocathode is placed directly in a high-gradient RF accelerating cavity. A photocathode allows unsurpassed control over the current, and the spatial and temporal profile of the beam. In addition the electrodeless emission'' avoids many of the difficulties associated with multi-electrode guns, i.e. the electrons are accelerated very rapidly to relativistic energies, and there are no electrodes to distort the accelerating fields. For the past two years we have been integrating a photocathode into our existing FEL facility by replacing our thermionic gun and subharmonic bunchers with a high-gradient 1.3 GHz photoinjector. The photoinjector, which is approximately 0.6 m in length, produces 6 MeV, 300 A, 15 ps linac, and accelerated to a final energy of 40 MeV. We have recently begun lasing at wavelengths near 3 {mu}m. 16 refs., 2 figs., 5 tabs.

  7. Spatial Model of Sky Brightness Magnitude in Langkawi Island, Malaysia

    Science.gov (United States)

    Redzuan Tahar, Mohammad; Kamarudin, Farahana; Umar, Roslan; Khairul Amri Kamarudin, Mohd; Hazmin Sabri, Nor; Ahmad, Karzaman; Rahim, Sobri Abdul; Sharul Aikal Baharim, Mohd

    2017-03-01

    Sky brightness is an essential topic in the field of astronomy, especially for optical astronomical observations that need very clear and dark sky conditions. This study presents the spatial model of sky brightness magnitude in Langkawi Island, Malaysia. Two types of Sky Quality Meter (SQM) manufactured by Unihedron are used to measure the sky brightness on a moonless night (or when the Moon is below the horizon), when the sky is cloudless and the locations are at least 100 m from the nearest light source. The selected locations are marked by their GPS coordinates. The sky brightness data obtained in this study were interpolated and analyzed using a Geographic Information System (GIS), thus producing a spatial model of sky brightness that clearly shows the dark and bright sky areas in Langkawi Island. Surprisingly, our results show the existence of a few dark sites nearby areas of high human activity. The sky brightness of 21.45 mag arcsec{}-2 in the Johnson-Cousins V-band, as the average of sky brightness equivalent to 2.8 × {10}-4{cd} {{{m}}}-2 over the entire island, is an indication that the island is, overall, still relatively dark. However, the amount of development taking place might reduce the number in the near future as the island is famous as a holiday destination.

  8. Brightness limitations of cold field emitters caused by Coulomb interactions

    NARCIS (Netherlands)

    Cook, B.J.; Verduin, T.; Hagen, C.W.; Kruit, P.

    2010-01-01

    Emission theory predicts that high brightness cold field emitters can enhance imaging in the electron microscope. This (neglecting chromatic aberration) is because of the large (coherent) probe current available from a high brightness source and is based on theoretically determined values of reduced

  9. Surface photometry of bulge dominated low surface brightness galaxies

    NARCIS (Netherlands)

    Beijersbergen, M; de Blok, WJG; van der Hulst, JM

    1999-01-01

    We present results of broad band BVRI observations of a sample of galaxies with a low surface brightness (LSB) disk and a bulge. These galaxies are well described as exponential disks and exponential bulges with no preferred value for either scale length or central surface brightness. The median B b

  10. Lamp spectrum and spatial brightness at photopic levels

    DEFF Research Database (Denmark)

    Fotios, Steve; Atli, Deniz; Cheal, Chris

    2015-01-01

    Light sources are available in a variety of spectral power distributions (SPDs) and this affects spatial brightness in a manner not predicted by quantities such as illuminance. Tuning light source SPD to better match the sensitivity of visual perception may allow the same spatial brightness but a...

  11. Analysis of Bright Harvest Remote Analysis for Residential Solar Installations

    Energy Technology Data Exchange (ETDEWEB)

    Nangle, John [National Renewable Energy Lab. (NREL), Golden, CO (United States); Simon, Joseph [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-06-17

    Bright Harvest provides remote shading analysis and design products for residential PV system installers. The National Renewable Energy Laboratory (NREL) through the NREL Commercialization Assistance Program, completed comparative assessments between on-site measurements and remotely calculated values to validate the accuracy of Bright Harvest’s remote shading and power generation.

  12. SDF-1γ/rhGM-CSF融合蛋白的制备及其趋化作用%Preparation of SDF-1γ/rhGM-CSF fusion protein and its chemotactic effect

    Institute of Scientific and Technical Information of China (English)

    居小萍; 徐新颜; 张晓青; 刘永明; 于春山; 曹洋森; 卢明智; 陈樱

    2011-01-01

    Objective:To prepare the fusion protein of SDF-1 and rhGM-CSF (SDF-17/rhGM-CSF) by genetic engineering technology, and investigate its hematopoietic and immune promotion functions in tumor patients. Methods; The expression vector for SDF-1γ/rhGM-CSF fusion protein, pPIC9k-SDFl-rhGM-CSFl, was constructed and the protein expression was induced by yeast transfection. SDF-1γ/rhGM-CSF fusion protein was further identified by Western blotting analysis. Colony-formation assay and chemoattract assay were used to study the roles of the prepared fusion protein in stimulating bone marrow cell colony-formation and in chemoattracting immature dendritic cells. Results; SDF-1 y/ rhGM-CSF fusion gene vector, pPIC9k-SDF1-rhGM-CSF1, was successfully constructed and expressed high level of SDF-1 y/rhGM-CSF fusion gene. The molecular weight of the expressed protein was about 25 000 and was recognized by GM-CSF specific antibody. The fusion protein had a stronger effect in stimulating bone marrow cell colony-formation than GM-CSF ( P < 0.05) and in chemoattracting immature dendritic cells than SDF-1 (P<0.05). Conclusion; SDF-1 -γ/rhGM-CSF fusion protein can promote bone marrow cell colony-formation and chemoattraction of immature dendritic cells, which might be used for promoting hematopoiesis and immune function of tumor patients after chemotherapy.%目的:利用基因工程技术制备SDF-1与hGM-CSF的融合蛋白(SDF-1γ/rhGM-CSF),研究该融合蛋白对肿瘤患者造血和免疫功能的增强作用.方法:构建表达SDF-1 γ/rhGM-CSF融合蛋白的pPIC9k-SDF1-rhGM-CSF1质粒,转染酵母菌,诱导SDF-1γ/rhGM-CSF融合蛋白的表达,Western blotting鉴定SDF-1γ/rhGM-CSF融合蛋白的表达.集落形成实验观察SDF-1γ/rhGM -CSF对骨髓细胞集落形成的影响,趋化实验检测其对未成熟树突状细胞(dendritic cell,DC)的趋化作用.结果:成功构建pPIC9k-SDF1 -rhGM-CSF1质粒,高表达SDF-1γ/rhGM-CSF融合蛋白,分子量约为25000,并可被GM

  13. Interpreting Central Surface Brightness and Color Profiles in Elliptical Galaxies

    Science.gov (United States)

    Silva, David R.; Wise, Michael W.

    1996-01-01

    Hubble Space Telescope imagery has revealed dust features in the central regions of many (50%--80%) nearby bright elliptical galaxies. If these features are an indication of an underlying smooth diffuse dust distribution, then the interpretation of central surface brightness and color profiles in elliptical galaxies becomes significantly more difficult. In this Letter, diagnostics for constraining the presence of such an underlying central dust distribution are presented. We show that easily detectable central color gradients and flattened central surface brightness profiles can be induced by even small amounts of smoothly distributed dust (~100 M⊙). Conversely, combinations of flat surface brightness profiles and flat color gradients or steep surface brightness profiles and steep color gradients are unlikely to be caused by dust. Taken as a whole, these results provide a simple observational tautology for constraining the existence of smooth diffuse dust distributions in the central regions of elliptical galaxies.

  14. Explaining the present GM business strategy on the EU food market: the gatekeepers' perspective.

    Science.gov (United States)

    Inghelbrecht, Linde; Dessein, Joost; Van Huylenbroeck, Guido

    2015-01-25

    The use of genetically modified (GM) crops and their applications is partially suppressed in European Union (EU) agriculture, even if one would expect otherwise given their complementarity with the neoliberal and industrialised EU agricultural regime in place. By applying a qualitative content analysis, this paper analyses how food manufacturers and retailers (referred to as gatekeepers in the food industry) explain and defend the exclusion of GM-labelled food products on the EU market. The study design places emphasis on the role of perceptions in the strategic behaviour of gatekeepers and on the role of interaction in this regard, as we assume that the way in which gatekeepers perceive the 'rules of the game' for commercialising GM crop applications on the EU food market will be influenced by their interaction with other agribusiness actors. In a first stage, the analysis determines thematic congruence in the (types of) perceptions that explain an agribusiness actor's overall interpretation of the EU business environment for GM crop applications. This perceived 'structuring arena' (SA) for GM crop applications - as conceptualised within our framework - contains areas of either internal and external tensions, that have a compelling or non-committal influence on the agribusiness actor's interpretation. In a second stage, the analysis particularly defines how gatekeepers in the food industry perceive and experience the SA for GM crop applications on the EU market, and how these perceptual tensions subsequently influence their strategic behaviour for GM-labelled products on the EU market. Finally, we highlight how these perceptions and actions (or inaction) suppress the main changes in practice that are necessary to manage this wicked problem.

  15. Ganglioside GM3 participates in the pathological conditions of insulin resistance.

    Science.gov (United States)

    Tagami, Seiichi; Inokuchi Ji, Jin-ichi; Kabayama, Kazuya; Yoshimura, Haruhiko; Kitamura, Futoshi; Uemura, Satoshi; Ogawa, Chie; Ishii, Atsushi; Saito, Masaki; Ohtsuka, Yoshinori; Sakaue, Shinji; Igarashi, Yasuyuki

    2002-02-01

    Gangliosides are known as modulators of transmembrane signaling by regulating various receptor functions. We have found that insulin resistance induced by tumor necrosis factor-alpha (TNF-alpha) in 3T3-L1 adipocytes was accompanied by increased GM3 ganglioside expression caused by elevating GM3 synthase activity and its mRNA. We also demonstrated that TNF-alpha simultaneously produced insulin resistance by uncoupling insulin receptor activity toward insulin receptor substrate-1 (IRS-1) and suppressing insulin-sensitive glucose transport. Pharmacological depletion of GM3 in adipocytes by an inhibitor of glucosylceramide synthase prevented the TNF-alpha-induced defect in insulin-dependent tyrosine phosphorylation of IRS-1 and also counteracted the TNF-alpha-induced serine phosphorylation of IRS-1. Moreover, when the adipocytes were incubated with exogenous GM3, suppression of tyrosine phosphorylation of insulin receptor and IRS-1 and glucose uptake in response to insulin stimulation was observed, demonstrating that GM3 itself is able to mimic the effects of TNF on insulin signaling. We used the obese Zucker fa/fa rat and ob/ob mouse, which are known to overproduce TNF-alpha mRNA in adipose tissues, as typical models of insulin resistance. We found that the levels of GM3 synthase mRNA in adipose tissues of these animals were significantly higher than in their lean counterparts. Taken together, the increased synthesis of cellular GM3 by TNF may participate in the pathological conditions of insulin resistance in type 2 diabetes.

  16. Differential expression of HLA-DR antigens in subsets of human CFU-GM.

    Science.gov (United States)

    Griffin, J D; Sabbath, K D; Herrmann, F; Larcom, P; Nichols, K; Kornacki, M; Levine, H; Cannistra, S A

    1985-10-01

    Expression of HLA-DR surface antigens by granulocyte/monocyte colony-forming cells (CFU-GM) may be important in the regulation of proliferation of these cells. Using immunological techniques to enrich for progenitor cells, we investigated the expression of HLA-DR in subsets of CFU-GM. "Early" (day 14) CFU-GM express higher levels of HLA-DR than do "late" (day 7) CFU-GM. Among late CFU-GM, cells destined to form monocyte (alpha-naphthyl acetate esterase-positive) colonies express higher levels of HLA-DR than do CFU-GM destined to form granulocyte (chloroacetate esterase-positive) colonies. Because high-level expression of DR antigen was a marker for monocyte differentiation, we examined several lymphokines for their effects on both DR expression and in vitro commitment to monocyte differentiation by myeloid precursor cells. DR antigen density could be increased by more than twofold over 48 hours upon exposure to gamma-interferon (gamma-IFN), whereas colony-stimulating factors had no effect. This was associated with a dose-dependent inhibition of total CFU-GM number, and a relative, but not absolute, increase in the ratio of monocyte colonies to granulocyte colonies. Similarly, in day 7 suspension cultures of purified myeloid precursor cells, gamma-IFN inhibited cell proliferation and increased the ratio of monocytes to granulocytes. Thus, despite the induction of high levels of HLA-DR antigen on precursor cells (a marker of monocyte commitment), the dominant in vitro effect of gamma-IFN was inhibition of granulocyte differentiation.

  17. Lower motor neuron syndrome associated with anti-GM1 antibodies.

    Science.gov (United States)

    Villa, A; Molina, H; Sanz, O P; Garreto, N; Kholer, G; Sica, R E

    1997-01-01

    It has been recently recognized that increased titers of serum anti-GM1 antibodies may be associated with motoneurone diseases or with multiple motor neuropathy with or without conduction block and also with chronic sensorimotor neuropathy and Guillain-Barré syndrome. Santoro et al. were the first to note that anti-GM1 antibodies were able to bind to the nodes of Ranvier of the sural nerve of a patient with clinical signs and symptoms mostly resembling amyotrophic lateral sclerosis who also showed, in nerve conduction studies, multifocal motor nerve fibers conduction block and serum IGM anti-GM1 antibodies. The two patients presented in this report had asymetrical motor neurone disease with signs and symptoms of lower motoneurone involvement, and other signs, in the first patient, which suggested the existence of upper motoneurone damage. Besides, the second patient also had clinical sensory impairment in the lower limbs. Electrophysiologically, none of them had nerve conduction block but both showed inexcitable median and sural nerve sensory fibers. Both had high titers of anti-GM1. A sural biopsy of both patients showed immunoglobulins into the sensory fibers. However, we do not know whether the anti-GM1 antibodies bind to a cross-reactive glycolipid other than the GM1 itself. In any case, it seems that the presence of anti-GM1 antibodies might be a marker signalling a potentially treatable immune disorder which may have signs of lower and upper motor neurone disease and, also, clinical and electrophysiological evidences of peripheral sensory involvement.

  18. GmFT2a polymorphism and maturity diversity in soybeans.

    Directory of Open Access Journals (Sweden)

    Bingjun Jiang

    Full Text Available BACKGROUND: Soybean is a short-day crop of agricultural, ecological, and economic importance. The sensitive photoperiod responses significantly limit its breeding and adaptation. GmFT2a, a putative florigen gene with different transcription profiles in two cultivars (late-maturing Zigongdongdou and early-maturing Heihe 27 with different maturity profiles, is key to flowering and maturation. However, up to now, its role in the diverse patterns of maturation in soybeans has been poorly understood. METHODS: Eighty varieties, including 19 wild accessions, covering 11 of all 13 maturity groups, were collected. They were planted in pots and maintained under different photoperiodicity conditions (SD, short day; LD, long day; and ND, natural day. The day to first flowering was recorded and the sensitivity to photoperiod was investigated. Polymorphisms in the GmFT2a coding sequence were explored by searching the known SNP database (NCBI dbSNP. The GmFT2a promoter regions were then cloned from these varieties and sequenced. Further polymorphism and association analyses were conducted. RESULTS: These varieties varied greatly in time to first flowering under ND and exhibited a consecutive distribution of photoperiod sensitivity, which suggested that there is rich diversity in flowering time. Furthermore, although GmFT2a had only one known synonymous SNP in the coding sequence, there were 17 haplotypes of the GmFT2a promoter region, HT06 of which was extremely abundant. Further association analysis found some SNPs that might be associated with day to first flowering and photoperiod sensitivity. CONCLUSION: Although GmFT2a is a key flowering gene, GmFT2a polymorphism does not appear to be responsible for maturity diversity in soybean.

  19. GmFT2a, a soybean homolog of FLOWERING LOCUS T, is involved in flowering transition and maintenance.

    Directory of Open Access Journals (Sweden)

    Hongbo Sun

    Full Text Available BACKGROUND: Flowering reversion can be induced in soybean (Glycine max L. Merr., a typical short-day (SD dicot, by switching from SD to long-day (LD photoperiods. This process may involve florigen, putatively encoded by FLOWERING LOCUS T (FT in Arabidopsis thaliana. However, little is known about the potential function of soybean FT homologs in flowering reversion. METHODS: A photoperiod-responsive FT homologue GmFT (renamed as GmFT2a hereafter was cloned from the photoperiod-sensitive cultivar Zigongdongdou. GmFT2a gene expression under different photoperiods was analyzed by real-time quantitative PCR. In situ hybridization showed direct evidence for its expression during flowering-related processes. GmFT2a was shown to promote flowering using transgenic studies in Arabidopsis and soybean. The effects of photoperiod and temperature on GmFT2a expression were also analyzed in two cultivars with different photoperiod-sensitivities. RESULTS: GmFT2a expression is regulated by photoperiod. Analyses of GmFT2a transcripts revealed a strong correlation between GmFT2a expression and flowering maintenance. GmFT2a transcripts were observed continuously within the vascular tissue up to the shoot apex during flowering. By contrast, transcripts decreased to undetectable levels during flowering reversion. In grafting experiments, the early-flowering, photoperiod-insensitive stock Heihe27 promotes the appearance of GmFT2a transcripts in the shoot apex of scion Zigongdongdou under noninductive LD conditions. The photothermal effects of GmFT2a expression diversity in cultivars with different photoperiod-sensitivities and a hypothesis is proposed. CONCLUSION: GmFT2a expression is associated with flowering induction and maintenance. Therefore, GmFT2a is a potential target gene for soybean breeding, with the aim of increasing geographic adaptation of this crop.

  20. Dark Skies, Bright Kids! Year 4

    Science.gov (United States)

    Sokal, Kimberly R.; Johnson, K. E.; Barcos-Munoz, L. D.; Beaton, R.; Borish, J.; Crawford, S. B.; Corby, J.; Damke, G.; Dean, J.; Dorsey, G.; Jackson, L.; Liss, S.; Oza, A.; Peacock, S.; Prager, B.; Romero, C.; Sivakoff, G. R.; Walker, L.; Whelan, D. G.; Zucker, C.

    2013-01-01

    Aiming to engage young children's natural excitement and curiosity, the outreach group Dark Skies, Bright Kids (DSBK) brings a hands-on approach to astronomy to elementary schools in Virginia. We hope to enhance children's view and understanding of science while exploring the Universe using fun activities. DSBK focuses on rural and underserved schools in Albemarle County and offers a semester-long astronomy club for third through fifth grade students. We believe regular interactions foster personal relationships between students and volunteers that encourage a life-long interest in science. In our fourth year of hosting clubs, we returned to Ivy Creek Elementary School, where we saw wonderful responses from a special group of students with `low-incidence' disabilities. DSBK has grown to realize a broader reach beyond local astronomy clubs; we hope to ignite a spark of interest in astronomy and science more widely- in more children, their families, and their teachers. We also hosted the Second Annual Central Virginia Star Party with an open invitation to the community to encourage families to enjoy astronomy together. Throughout the year, DSBK now holds 'one-off' programs (akin to astronomy field days) for elementary schools and children's groups throughout Virginia. Furthermore, we are in the final stages of a project to create two bilingual astronomy books called "Snapshots of the Universe", in Spanish and French with English translations. This art book will be made available online and we are working to get a copy in every elementary school in the state. DSBK has begun to reach out to elementary school teachers in order to provide them with useful and engaging classroom material. We have adapted our volunteer-created activities into useful and ready-to-use lessons, available online. After improvements based on research through interactions and feedback from teachers, we have explicitly identified the learning goals in terms of Virginia's Standards of Learning

  1. Dark Skies, Bright Kids: Year 2

    Science.gov (United States)

    Carlberg, Joleen K.; Johnson, K.; Lynch, R.; Walker, L.; Beaton, R.; Corby, J.; de Messieres, G.; Drosback, M.; Gugliucci, N.; Jackson, L.; Kingery, A.; Layman, S.; Murphy, E.; Richardson, W.; Ries, P.; Romero, C.; Sivakoff, G.; Sokal, K.; Trammell, G.; Whelan, D.; Yang, A.; Zasowski, G.

    2011-01-01

    The Dark Skies, Bright Kids (DSBK) outreach program brings astronomy education into local elementary schools in central Virginia's Southern Albemarle County through an after-school club. Taking advantage of the unusually dark night skies in the rural countryside, DSBK targets economically disadvantaged schools that tend to be underserved due to their rural locale. The goals of DSBK are to foster children's natural curiosity, demonstrate that science is a fun and creative process, challenge students' conceptions of what a scientist is and does, and teach some basic astronomy. Furthermore, DSBK works to assimilate families into students' education by holding family observing nights at the school. Now in its third semester, DSBK has successfully run programs at two schools with very diverse student populations. Working with these students has helped us to revise our activities and to create new ones. A by-product of our work has been the development of lesson plans, complete with learning goals and detailed instructions, that we make publically available on our website. This year we are expanding our repertoire with our new planetarium, which allows us to visualize topics in novel ways and supplements family observing on cloudy nights. The DSBK volunteers have also created a bilingual astronomy artbook --- designed, written, and illustrated by UVa students --- that we will publish and distribute to elementary schools in Virginia. Our book debuted at the last AAS winter meeting, and since then it has been extensively revised and updated with input from many individuals, including parents, professional educators, and a children's book author. Because the club is currently limited to serving a few elementary schools, this book will be part of our efforts to broaden our impact by bringing astronomy to schools we cannot go to ourselves and reaching out to Spanish-speaking communities at the same time.

  2. Dark Skies, Bright Kids! Year 3

    Science.gov (United States)

    Whelan, David G.; Johnson, K. E.; Barcos-Munoz, L. D.; Beaton, R. L.; Borish, J.; Corby, J. F.; Dorsey, G.; Gugliucci, N. E.; Prager, B. J.; Ries, P. A.; Romero, C. E.; Sokal, K. R.; Tang, X.; Walker, L. M.; Yang, A. J.; Zasowski, G.

    2012-01-01

    Dark Skies, Bright Kids! (DSBK) is a program that brings astronomy education to elementary schools throughout central Virginia. In a relaxed, out-of-classroom atmosphere, we are able to foster the innate curiosity that young students have about science and the world around them. We target schools that are under-served due to their rural locale or special needs students, demonstrating that science is a fun and creative process to a segment of the population that might not otherwise be exposed to astronomy. Families are included in the learning experience during semi-annual `star parties'. Since last January, we have expanded the breadth and depth of our educational capabilities. We have developed new programs for use in our digital planetarium. We held the first Central Virginia Star Party, providing an atmosphere where local children from multiple schools were able to share their love for astronomy. Local government and University officials were also invited so that they could experience our focused science outreach. Most recently, we have become part of Ivy Creek School's Club Day activities, bringing our program to a new segment of the elementary school system in Albemarle County: those that have `low-incidence' disabilities, requiring special attention. We continue to develop a curriculum for after-school programs that functions as either a series of one-time activities or several months of focused outreach at one school. Many of these activities are provided on our website, http://www.astro.virginia.edu/dsbk/, for the wider astronomical community, including the new planetarium work. We have extended our book project to include two bilingual astronomy books called `Snapshots of the Universe,' one in Spanish and English, the other in French and English. These books introduce young people to some of the many wonders of the Universe through art and captions developed by DSBK volunteers.

  3. Bright Times for an Ancient Star

    Science.gov (United States)

    Fuhrmann, K.; Chini, R.

    2017-01-01

    Field stars of Population II are among the oldest sources in the Galaxy. Most of their solar-type dwarfs are non-single and, given their extreme age, a significant fraction is accompanied by stellar remnants. Here we report the discovery of the bright F7V star 49 Lib as a massive and very metal-rich Population II field blue straggler, along with evidence for a white dwarf as its dark and unseen companion. 49 Lib is known as a relatively fast-rotating, single-lined spectroscopic binary in a 3 year orbit and with an apparent age of about τ ≃ 2.3 Gyr. Its chemistry and kinematics, however, both consistently imply that 49 Lib must be an ancient Population II star at τ ≃ 12 Gyr. With reference to the inclination from the astrometric orbit, leading to a {M}{WD}={0.50}-0.04+0.03 M⊙ low-mass white dwarf, and in view of the {M}{BS}={1.55}-0.13+0.07 M⊙ massive, evolved F-type blue straggler star, we demonstrate that 49 Lib must have been the subject of a mostly conservative mass transfer with a near-equal-mass M ≃ 1.06 + 1.00 M⊙ G-type binary at birth. For its future evolution, we point to the possibility as a progenitor system toward a type Ia supernova. Most importantly, however, we note that the remarkable metal enrichment of 49 Lib at [Mg/H] = +0.23 and [Fe/H] = ‑0.11 has principally very relevant implications for the early epoch when the Milky Way came into being.

  4. MAGNETIC FLUX SUPPLEMENT TO CORONAL BRIGHT POINTS

    Energy Technology Data Exchange (ETDEWEB)

    Mou, Chaozhou; Huang, Zhenghua; Xia, Lidong; Li, Bo; Fu, Hui; Jiao, Fangran; Hou, Zhenyong [Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial Environment, Institute of Space Sciences, Shandong University, Weihai, 264209 Shandong (China); Madjarska, Maria S., E-mail: z.huang@sdu.edu.cn [Armagh Observatory, College Hill, Armagh BT61 9DG (United Kingdom)

    2016-02-10

    Coronal bright points (BPs) are associated with magnetic bipolar features (MBFs) and magnetic cancellation. Here we investigate how BP-associated MBFs form and how the consequent magnetic cancellation occurs. We analyze longitudinal magnetograms from the Helioseismic and Magnetic Imager to investigate the photospheric magnetic flux evolution of 70 BPs. From images taken in the 193 Å passband of the Atmospheric Imaging Assembly (AIA) we dermine that the BPs’ lifetimes vary from 2.7 to 58.8 hr. The formation of the BP MBFs is found to involve three processes, namely, emergence, convergence, and local coalescence of the magnetic fluxes. The formation of an MBF can involve more than one of these processes. Out of the 70 cases, flux emergence is the main process of an MBF buildup of 52 BPs, mainly convergence is seen in 28, and 14 cases are associated with local coalescence. For MBFs formed by bipolar emergence, the time difference between the flux emergence and the BP appearance in the AIA 193 Å passband varies from 0.1 to 3.2 hr with an average of 1.3 hr. While magnetic cancellation is found in all 70 BPs, it can occur in three different ways: (I) between an MBF and small weak magnetic features (in 33 BPs); (II) within an MBF with the two polarities moving toward each other from a large distance (34 BPs); (III) within an MBF whose two main polarities emerge in the same place simultaneously (3 BPs). While an MBF builds up the skeleton of a BP, we find that the magnetic activities responsible for the BP heating may involve small weak fields.

  5. Geographical distribution of GmTfl1 alleles in Chinese soybean varieties

    Institute of Scientific and Technical Information of China (English)

    Guifeng; Liu; Lin; Zhao; Benjamin; J.Averitt; Ying; Liu; Bo; Zhang; Ruzhen; Chang; Yansong; Ma; Xiaoyan; Luan; Rongxia; Guan; Lijuan; Qiu

    2015-01-01

    Stem growth habit is an important agronomic trait in soybean and is subject to artificial selection. This study aimed to provide a theory for genotypic selection of stem growth habit for breeding purposes by analyzing the alleles of Gm Tfl1 gene in Chinese soybean varieties and establishing a database of Gm Tfl1 variation. Using knowledge of insertion and deletion(Indel) in the non-coding region and four single-nucleotide polymorphisms(SNPs) in the coding sequences of the Gm Tfl1 gene, four CAPS and one Indel markers were developed and used to test 1120 Chinese soybean varieties. We found that the dominant Gm Tfl1 allele was prevalent in accessions from the Northern ecoregion, whereas the recessive allele, Gmtfl1, was more common in the Southern ecoregion, and the proportions of Gm Tfl1 and recessive alleles were respectively 40.1% and 59.9% in the Huang-Huai ecoregion. The proportion of Gm Tfl1 decreased and that of Gmtfl1 increased, gradually from north to south. Allele Gm Tfl1-a was present in higher proportions in the Huang-Huai spring, Huang-Huai summer, and Northern spring sub-ecoregions than that in the other sub-ecoregions. Gm Tfl1-b was common in the Northeast spring, Northern spring and Southern summer sub-ecoregions. Gmtfl1-ta was found mainly in the Huang-Huai spring,Huang-Huai summer and Southern spring sub-ecoregions. The Gmtfl1-ab allele was distributed in all six soybean sub-ecoregions. The Gmtfl1-bb allele was distributed mainly in the Huang-Huai spring and summer and Southern spring and summer sub-ecoregions,but the Gmtfl1-tb allele was detected only in the Huang-Huai summer sub-ecoregion. The distributions of Gm Tfl1 and Gmtfl1 have shown no large changes in nearly 60 years of breeding, but the frequency of the recessive genotype Gmtfl1 has shown a rising trend in the last 20 years. This study provides a theoretical foundation for breeding new soybean varieties for different ecoregions.

  6. Isolation and Characterization of the Brassinosteroid Receptor Gene (GmBRI1 from Glycine max

    Directory of Open Access Journals (Sweden)

    Miao Wang

    2014-03-01

    Full Text Available Brassinosteroids (BRs constitute a group of steroidal phytohormones that contribute to a wide range of plant growth and development functions. The genetic modulation of BR receptor genes, which play major roles in the BR signaling pathway, can create semi-dwarf plants that have great advantages in crop production. In this study, a brassinosteroid insensitive gene homologous with AtBRI1 and other BRIs was isolated from Glycine max and designated as GmBRI1. A bioinformatic analysis revealed that GmBRI1 shares a conserved kinase domain and 25 tandem leucine-rich repeats (LRRs that are characteristic of a BR receptor for BR reception and reaction and bear a striking similarity in protein tertiary structure to AtBRI1. GmBRI1 transcripts were more abundant in soybean hypocotyls and could be upregulated in response to exogenous BR treatment. The transformation of GmBRI1 into the Arabidopsis dwarf mutant bri1-5 restored the phenotype, especially regarding pod size and plant height. Additionally, this complementation is a consequence of a restored BR signaling pathway demonstrated in the light/dark analysis, root inhibition assay and BR-response gene expression. Therefore, GmBRI1 functions as a BR receptor to alter BR-mediated signaling and is valuable for improving plant architecture and enhancing the yield of soybean.

  7. Overexpression of Soybean Isoflavone Reductase (GmIFR) Enhances Resistance to Phytophthora sojae in Soybean.

    Science.gov (United States)

    Cheng, Qun; Li, Ninghui; Dong, Lidong; Zhang, Dayong; Fan, Sujie; Jiang, Liangyu; Wang, Xin; Xu, Pengfei; Zhang, Shuzhen

    2015-01-01

    Isoflavone reductase (IFR) is an enzyme involved in the biosynthetic pathway of isoflavonoid phytoalexin in plants. IFRs are unique to the plant kingdom and are considered to have crucial roles in plant response to various biotic and abiotic environmental stresses. Here, we report the characterization of a novel member of the soybean isoflavone reductase gene family GmIFR. Overexpression of GmIFR transgenic soybean exhibited enhanced resistance to Phytophthora sojae. Following stress treatments, GmIFR was significantly induced by P. sojae, ethephon (ET), abscisic acid (placeCityABA), salicylic acid (SA). It is located in the cytoplasm when transiently expressed in soybean protoplasts. The daidzein levels reduced greatly for the seeds of transgenic plants, while the relative content of glyceollins in transgenic plants was significantly higher than that of non-transgenic plants. Furthermore, we found that the relative expression levels of reactive oxygen species (ROS) of transgenic soybean plants were significantly lower than those of non-transgenic plants after incubation with P. sojae, suggesting an important role of GmIFR might function as an antioxidant to reduce ROS in soybean. The enzyme activity assay suggested that GmIFR has isoflavone reductase activity.

  8. Conflicts of Interest in GM Bt Crop Efficacy and Durability Studies

    Science.gov (United States)

    Lombaert, Eric

    2016-01-01

    Public confidence in genetically modified (GM) crop studies is tenuous at best in many countries, including those of the European Union in particular. A lack of information about the effects of ties between academic research and industry might stretch this confidence to the breaking point. We therefore performed an analysis on a large set of research articles (n = 672) focusing on the efficacy or durability of GM Bt crops and ties between the researchers carrying out these studies and the GM crop industry. We found that ties between researchers and the GM crop industry were common, with 40% of the articles considered displaying conflicts of interest (COI). In particular, we found that, compared to the absence of COI, the presence of a COI was associated with a 50% higher frequency of outcomes favorable to the interests of the GM crop company. Using our large dataset, we were able to propose possible direct and indirect mechanisms behind this statistical association. They might notably include changes of authorship or funding statements after the results of a study have been obtained and a choice in the topics studied driven by industrial priorities. PMID:27977705

  9. Phase I dose intensification study of 2-weekly epirubicin with GM-CSF in advanced cancer.

    Science.gov (United States)

    Michael, M; Toner, G C; Olver, I N; Fenessy, A; Bishop, J F

    1997-06-01

    This study investigated dose intensification of epirubicin administered as a 2-weekly regimen with granulocyte-macrophage colony-stimulating factor (GM-CSF) support. The aim was to define the maximally tolerated dose of epirubicin and to assess the efficacy of GM-CSF to ameliorate its toxicity. Patients with anthracycline-responsive advanced malignancies were eligible. Six dose levels, commencing at 90 mg/m2, of epirubicin administered every 2 weeks for four courses were planned with GM-CSF 10 micrograms/kg/day administered for 10 days from the second day of each course. Six patients were to be entered at each dose level, and escalation to the next level was based upon toxicity criteria. Twelve patients were entered, six at dose level 1 (90 mg/m2) and six at dose level 2 (120 mg/m2). Prospectively defined haematological dose-limiting toxicities were noted in one patient at dose level 1 and in five patients at dose level 2. Further dose escalation was not attempted. Significant nonhaematological toxicities included febrile neutropenia in two and four patients at dose levels 1 and 2, respectively. This study has demonstrated that epirubicin can be safely administered at 2 week intervals with GM-CSF at a dose of 90 mg/m2, equivalent to the previously reported maximum tolerated dose intensity of 45 mg/m2/week. Neutropenia was dose-limiting despite the use of GM-CSF.

  10. New serum markers for small-cell lung cancer. I. The ganglioside fucosyl-GM1

    DEFF Research Database (Denmark)

    Vangsted, A; Drivsholm, L; Andersen, E;

    1994-01-01

    The ganglioside fucosyl-GM1 (FucGM1) has been suggested as a marker for small-cell lung cancer (SCLC). Immunohistochemical analyses have shown the expression of the ganglioside in tumors in 75 to 90% of patients with SCLC. We have demonstrated that the ganglioside is shedded from SCLC cells both...... an immunoassay based on the scintillation proximity assay to analyze the concentrations of FucGM1 in sera from 112 SCLC patients, 21 patients with non-SCLC, 4 patients with other cancer forms, and 20 healthy controls. Sera were collected at the time of diagnosis before initiation of chemotherapy. The expression...... of FucGM1 was related to age, sex, blood group of the patient, and to the stage of disease and organ site involvement of metastases. The sera of 50% of the patients with SCLC were positive for FucGM1, and 12 of 21 sera from non-SCLC patients were markedly elevated. In SCLC sera, the concentration of Fuc...

  11. Coexistence between conventional, organic and GM crops production: the Portuguese system.

    Science.gov (United States)

    Chiarabolli, Alessandro

    2011-01-01

    The objective of this paper is to analyze the way of Portugal is addressing the issue of the coexistence between conventional, organic and Genetically Modified (GM) crops production. In the EU, no form of agriculture, be it conventional, organic or transgenic, should be excluded. Farmers are free to choose the production type they prefer, without being forced to change patterns already established in the area and without spending more resources. Farmers' choice of growing GM or non-GM crops depends not only on technical aspects related to the productivity gains and agronomic benefits to be gained from adopting this technology, but also on consumers' preferences. Today only few Member States have adopted specific legislation on coexistence. Portugal was one of the first European Country that, in 2005, adopted a coexistence law and it has implemented one of the most complete systems of coexistence regulation. Today Portugal has a well-balanced regime based on free choice for consumers and growers. It has a coexistence system complete regulation and farmers who wish to cultivate GM maize must fulfill with national coexistence legislation that includes the following compulsory rules: participate in specific coexistence training courses, register the cultivation area, inform by written notification about their intent to cultivate GM, apply measures of coexistence, among others.

  12. GM1 ganglioside is involved in epigenetic activation loci of neuronal cells

    Science.gov (United States)

    Tsai, Yi-Tzang; Itokazu, Yutaka; Yu, Robert K.

    2015-01-01

    Gangliosides are sialic acid-containing glycosphingolipids that are most abundant in the nerve tissues. The quantity and expression pattern of gangliosides in brain change drastically throughout development and are mainly regulated through stage-specific expression of glycosyltransferase (ganglioside synthase) genes. We previously demonstrated that acetylation of histones H3 and H4 on the N-acetylgalactosaminyltransferase I (GalNAcT, GA2/GM2/GD2/GT2-synthase) gene promoter resulted in recruitment of trans-activation factors. In addition, we reported that epigenetic activation of the GalNAcT gene was also detected as accompanied by an apparent induction of neuronal differentiation in neural stem cells responding to an exogenous supplement of ganglioside GM1. Here, we present evidence supporting the concept that nuclear GM1 is associated with gene regulation in neuronal cells. We found that nuclear GM1 binds acetylated histones on the promoters of the GalNAcT and NeuroD1 genes in differentiated neurons. Our study demonstrates for the first time that GM1 interacts with chromatin via acetylated histones at the nuclear periphery of neuronal cells. PMID:26498762

  13. Quantitative Brightness Analysis of Fluorescence Intensity Fluctuations in E. Coli.

    Science.gov (United States)

    Hur, Kwang-Ho; Mueller, Joachim D

    2015-01-01

    The brightness measured by fluorescence fluctuation spectroscopy specifies the average stoichiometry of a labeled protein in a sample. Here we extended brightness analysis, which has been mainly applied in eukaryotic cells, to prokaryotic cells with E. coli serving as a model system. The small size of the E. coli cell introduces unique challenges for applying brightness analysis that are addressed in this work. Photobleaching leads to a depletion of fluorophores and a reduction of the brightness of protein complexes. In addition, the E. coli cell and the point spread function of the instrument only partially overlap, which influences intensity fluctuations. To address these challenges we developed MSQ analysis, which is based on the mean Q-value of segmented photon count data, and combined it with the analysis of axial scans through the E. coli cell. The MSQ method recovers brightness, concentration, and diffusion time of soluble proteins in E. coli. We applied MSQ to measure the brightness of EGFP in E. coli and compared it to solution measurements. We further used MSQ analysis to determine the oligomeric state of nuclear transport factor 2 labeled with EGFP expressed in E. coli cells. The results obtained demonstrate the feasibility of quantifying the stoichiometry of proteins by brightness analysis in a prokaryotic cell.

  14. Quantitative Brightness Analysis of Fluorescence Intensity Fluctuations in E. Coli.

    Directory of Open Access Journals (Sweden)

    Kwang-Ho Hur

    Full Text Available The brightness measured by fluorescence fluctuation spectroscopy specifies the average stoichiometry of a labeled protein in a sample. Here we extended brightness analysis, which has been mainly applied in eukaryotic cells, to prokaryotic cells with E. coli serving as a model system. The small size of the E. coli cell introduces unique challenges for applying brightness analysis that are addressed in this work. Photobleaching leads to a depletion of fluorophores and a reduction of the brightness of protein complexes. In addition, the E. coli cell and the point spread function of the instrument only partially overlap, which influences intensity fluctuations. To address these challenges we developed MSQ analysis, which is based on the mean Q-value of segmented photon count data, and combined it with the analysis of axial scans through the E. coli cell. The MSQ method recovers brightness, concentration, and diffusion time of soluble proteins in E. coli. We applied MSQ to measure the brightness of EGFP in E. coli and compared it to solution measurements. We further used MSQ analysis to determine the oligomeric state of nuclear transport factor 2 labeled with EGFP expressed in E. coli cells. The results obtained demonstrate the feasibility of quantifying the stoichiometry of proteins by brightness analysis in a prokaryotic cell.

  15. Knowledge, attitudes and behavioral intentions of agricultural professionals toward genetically modified (GM) foods: a case study in Southwest Iran

    OpenAIRE

    Ghasemi, Sedigheh; Karami, Ezatollah; AZADI, Hossein

    2013-01-01

    While there has been a number of consumers' studies looking at factors that influence individuals' attitudes and behavior toward GM foods, few studies have considered agricultural professionals' intentions in this regard. This study illuminates agricultural professionals' insights toward GM foods in Southwest Iran. A random sample of 262 respondents was studied. The results indicated that the majority of the respondents had little knowledge about GM foods. They perceived few benefits or risks...

  16. Variations in the Bivariate Brightness Distribution with different galaxy types

    CERN Document Server

    Cross, N; Lemon, D; Liske, J; Cross, Nicholas; Driver, Simon; Lemon, David; Liske, Jochen

    2002-01-01

    We present Bivariate Brightness Distributions (BBDs) for four spectral types discriminated by the 2dFGRS. We discuss the photometry and completeness of the 2dFGRS using a deep, wide-field CCD imaging survey. We find that there is a strong luminosity-surface brightness correlation amongst galaxies with medium to strong emission features, with gradient $\\beta_{\\mu}=0.25\\pm0.05$ and width $\\sigma_{\\mu}=0.56\\pm0.01$. Strong absorption line galaxies, show a bimodal distribution, with no correlation between luminosity and surface brightness.

  17. Low dimensional neutron moderators for enhanced source brightness

    DEFF Research Database (Denmark)

    Mezei, Ferenc; Zanini, Luca; Takibayev, Alan;

    2014-01-01

    In a recent numerical optimization study we have found that liquid para-hydrogen coupled cold neutron moderators deliver 3–5 times higher cold neutron brightness at a spallation neutron source if they take the form of a flat, quasi 2-dimensional disc, in contrast to the conventional more voluminous...... for cold neutrons. This model leads to the conclusions that the optimal shape for high brightness para-hydrogen neutron moderators is the quasi 1-dimensional tube and these low dimensional moderators can also deliver much enhanced cold neutron brightness in fission reactor neutron sources, compared...

  18. Insulation co-ordination and the enlargement law for the GM counter tube

    Directory of Open Access Journals (Sweden)

    Dolićanin Edin Ć.

    2016-01-01

    Full Text Available In this paper we analyze application of contemporary methods of insulation co-ordination and the enlargement law in designing a GM counting tube. It has been shown that by applying insulation co-ordination methods the counting tube can be optimally dimensioned. The application of the enlargement law was demonstrated in generalizing the results of test obtained by the GM tube to those obtained by the counting tube with m-times greater dimensions. The investigations were conducted both theoretically and by experiment. Using theoretical analysis, we derived the expressions that may be applied if a performance function of a random variable breakdown voltage is known. The experiments were conducted on a GM counter model under well controlled laboratory conditions.

  19. GM-PHD Filter Combined with Track-Estimate Association and Numerical Interpolation

    Directory of Open Access Journals (Sweden)

    Jinguang Chen

    2015-01-01

    Full Text Available For the standard Gaussian mixture probability hypothesis density (GM-PHD filter, the number of targets can be overestimated if the clutter rate is too high or underestimated if the detection rate is too low. These problems seriously affect the accuracy of multitarget tracking for the number and the value of measurements and clutters cannot be distinguished and recognized. Therefore, we proposed an improved GM-PHD filter to tackle these problems. Firstly, a track-estimate association was implemented in the filtering process to detect and remove false-alarm targets. Secondly, a numerical interpolation technique was used to compensate the missing targets caused by low detection rate. At the end of this paper, simulation results were presented to demonstrate the proposed GM-PHD algorithm is more effective in estimating the number and state of targets than the previous ones.

  20. Using environmental bonds to regulate the risks of GM crops: problems and prospects.

    Science.gov (United States)

    Mooney, Siân; Gerard, David

    2003-01-01

    We examine the characteristics and limitations of the existing system of tort liability for addressing potential environmental damages from GM crops and consider whether environmental bonding could be used to address these risks. We find that in the case of GM crops, a bonding mechanism would complement some of the strengths of tort liability. Specifically, the bonding mechanism provides some protection against bankruptcy, and also shifts the burden of risk toward life science companies that develop the technology. These factors could encourage additional early research by life science firms. However, a bonding mechanism adds to the regulatory apparatus, and would likely increase administrative costs, over tort liability, for public and private parties. Nevertheless, an attractive possibility is that the cumulative outcomes of bonding, e.g., shifting the risk burden, providing a measure of bankruptcy protection, and introducing an additional regulatory component, would mitigate some of the political and social objections to the environmental release of GM crops.

  1. Improved NN-GM(1,1 for Postgraduates’ Employment Confidence Index Forecasting

    Directory of Open Access Journals (Sweden)

    Lu Wang

    2014-01-01

    Full Text Available Postgraduates’ employment confidence index (ECI forecasting can help the university to predict the future trend of postgraduates’ employment. However, the common forecast method based on the grey model (GM has unsatisfactory performance to a certain extent. In order to forecast postgraduates’ ECI efficiently, this paper discusses a novel hybrid forecast model using limited raw samples. Different from previous work, the residual modified GM(1,1 model is combined with the improved neural network (NN in this work. In particullar, the hybrid model reduces the residue of the standard GM(1,1 model as well as accelerating the convergence rate of the standard NN. After numerical studies, the illustrative results are provided to demonstrate the forecast performance of the proposed model. In addition, some strategies for improving the postgraduates’ employment confidence have been discussed.

  2. GmNAC5, a NAC Transcription Factor, Is a Transient Response Regulator Induced by Abiotic Stress in Soybean

    OpenAIRE

    2013-01-01

    GmNAC5 is a member of NAM subfamily belonging to NAC transcription factors in soybean (Glycine max (L.) Merr.). Studies on NAC transcription factors have shown that this family functioned in the regulation of shoot apical meristem (SAM), hormone signalling, and stress responses. In this study, we examined the expression levels of GmNAC5. GmNAC5 was highly expressed in the roots and immature seeds, especially strongly in immature seeds of 40 days after flowering. In addition, we found that Gm...

  3. Isolation and characterization of "GmScream" promoters that regulate highly expressing soybean (Glycine max Merr.) genes.

    Science.gov (United States)

    Zhang, Ning; McHale, Leah K; Finer, John J

    2015-12-01

    To increase our understanding of the regulatory components that control gene expression, it is important to identify, isolate and characterize new promoters. In this study, a group of highly expressed soybean (Glycine max Merr.) genes, which we have named "GmScream", were first identified from RNA-Seq data. The promoter regions were then identified, cloned and fused with the coding region of the green fluorescent protein (gfp) gene, for introduction and analysis in different tissues using 3 tools for validation. Approximately half of the GmScream promoters identified showed levels of GFP expression comparable to or higher than the Cauliflower Mosaic Virus 35S (35S) promoter. Using transient expression in lima bean cotyledonary tissues, the strongest GmScream promoters gave over 6-fold higher expression than the 35S promoter while several other GmScream promoters showed 2- to 3-fold higher expression. The two highest expressing promoters, GmScreamM4 and GmScreamM8, regulated two different elongation factor 1A genes in soybean. In stably transformed soybean tissues, GFP driven by the GmScreamM4 or GmScreamM8 promoter exhibited constitutive high expression in most tissues with preferentially higher expression in proliferative embryogenic tissues, procambium, vascular tissues, root tips and young embryos. Using deletion analysis of the promoter, two proximal regions of the GmScreamM8 promoter were identified as contributing significantly to high levels of gene expression.

  4. Implicit attitudes towards genetically modified (GM) foods: a comparison of context-free and context-dependent evaluations.

    Science.gov (United States)

    Spence, Alexa; Townsend, Ellen

    2006-01-01

    Past research on attitudes towards GM food has focused on measuring explicit attitudes. Here we compared implicit attitudes towards GM foods with explicit attitudes towards GM foods. We used the Go No-Go task to investigate context-free implicit evaluations of GM foods and compared these with evaluations made in the context of ordinary and organic foods. Semantic differential scales were used to evaluate explicit attitudes towards GM foods. As expected, explicit attitudes towards GM foods were found to be neutral. However, contrary to our hypotheses, participants were found to hold positive, rather than neutral, implicit attitudes towards GM foods when these were assessed in a context free manner. In addition, neutral implicit attitudes were found when attitudes were assessed in the context of ordinary or organic foods, again contrasting with our hypotheses. These results imply that implicit attitudes towards GM food are more positive than anticipated and may lead to approach behaviour towards such products. Thus, given the choice, consumers are likely to accept GM food although other incentives may be needed if alternative foods are available.

  5. Using GM (1,1 Optimized by MFO with Rolling Mechanism to Forecast the Electricity Consumption of Inner Mongolia

    Directory of Open Access Journals (Sweden)

    Huiru Zhao

    2016-01-01

    Full Text Available Accurate and reliable forecasting on annual electricity consumption will be valuable for social projectors and power grid operators. With the acceleration of electricity market reformation and the development of smart grid and the energy Internet, the modern electric power system is becoming increasingly complex in terms of structure and function. Therefore, electricity consumption forecasting has become a more difficult and challenging task. In this paper, a new hybrid electricity consumption forecasting method, namely grey model (1,1 (GM (1,1, optimized by moth-flame optimization (MFO algorithm with rolling mechanism (Rolling-MFO-GM (1,1, was put forward. The parameters a and b of GM (1,1 were optimized by employing moth-flame optimization algorithm (MFO, which is the latest natured-inspired meta-heuristic algorithm proposed in 2015. Furthermore, the rolling mechanism was also introduced to improve the precision of prediction. The Inner Mongolia case discussion shows the superiority of proposed Rolling-MFO-GM (1,1 for annual electricity consumption prediction when compared with least square regression (LSR, GM (1,1, FOA (fruit fly optimization-GM (1,1, MFO-GM (1,1, Rolling-LSR, Rolling-GM (1,1 and Rolling-FOA-GM (1,1. The grey forecasting model optimized by MFO with rolling mechanism can improve the forecasting performance of annual electricity consumption significantly.

  6. A Novel Soybean ERF Transcription Factor, GmERF113, Increases Resistance to Phytophthora sojae Infection in Soybean

    Science.gov (United States)

    Zhao, Yuanling; Chang, Xin; Qi, Dongyue; Dong, Lidong; Wang, Guangjin; Fan, Sujie; Jiang, Liangyu; Cheng, Qun; Chen, Xi; Han, Dan; Xu, Pengfei; Zhang, Shuzhen

    2017-01-01

    Phytophthora root and stem rot of soybean caused by the oomycete Phytophthora sojae, is a destructive disease worldwide. Ethylene response factors (ERFs) play important roles in regulating plant biotic and abiotic stress tolerance. In this study, a new ERF gene, GmERF113, was isolated from the highly resistant soybean ‘Suinong 10.’ Sequence analysis suggested that the protein encoded by GmERF113 contained a conserved AP2/ERF domain of 58 amino acid and belonged to the B-4 subgroup of the ERF subfamily. Expression of GmERF113 was significantly induced by P. sojae, ethylene, and methyl jasmonate. GmERF113 protein localized to the nucleus when transiently expressed in Arabidopsis protoplasts, could bind to the GCC-box, and acted as a transcription activator. In addition, a region of the full-length GmERF113, GmERF113-II, interacted with a basic helix-loop-helix transcription factor (GmbHLH) in yeast cells. Full-length GmERF113 also interacted with GmbHLH in planta. GmERF113-overexpressing transgenic plants in susceptible cultivar ‘Dongnong 50’ soybean exhibited increased resistance to P. sojae and positively regulated the expression of the pathogenesis-related genes, PR1 and PR10-1. These results indicate that GmERF113 may play a crucial role in the defense of soybean against P. sojae infection. PMID:28326092

  7. Investigating factors influencing consumer willingness to buy GM food and nano-food

    Science.gov (United States)

    Yue, Chengyan; Zhao, Shuoli; Cummings, Christopher; Kuzma, Jennifer

    2015-07-01

    Emerging technologies applied to food products often evoke controversy about their safety and whether to label foods resulting from their use. As such, it is important to understand the factors that influence consumer desires for labeling and their willingness-to-buy (WTB) these food products. Using data from a national survey with US consumers, this study employs structural equation modeling to explore relationships between potential influences such as trust in government to manage technologies, views on restrictive government policies, perceptions about risks and benefits, and preferences for labeling on consumer's WTB genetically modified (GM) and nano-food products. Some interesting similarities and differences between GM- and nano-food emerged. For both technologies, trust in governing agencies to manage technologies did not influence labeling preferences, but it did influence attitudes about the food technologies themselves. Attitudes toward the two technologies, as measured by risk-benefit comparisons and comfort with consumption, also greatly influenced views of government restrictive policies, labeling preferences, and WTB GM or nano-food products. For differences, labeling preferences were found to influence WTB nano-foods, but not WTB GM foods. Gender and religiosity also had varying effects on WTB and labeling preferences: while gender and religiosity influenced labeling preferences and WTB for GM foods, they did not have a significant influence for nano-foods. We propose some reasons for these differences, such as greater media attention and other heuristics such as value-based concerns about "modifying life" with GM foods. The results of this study can help to inform policies and communication about the application of these new technologies in food products.

  8. Investigating factors influencing consumer willingness to buy GM food and nano-food

    Energy Technology Data Exchange (ETDEWEB)

    Yue, Chengyan [University of Minnesota-Twin Cities, Departments of Applied Economics and Horticultural Science, Bachman Endowed Chair in Horticultural Marketing (United States); Zhao, Shuoli [University of Minnesota-Twin Cities, Department of Applied Economics (United States); Cummings, Christopher [Nanyang Technological University, Division of Communication Research, Wee Kim Wee School of Communication and Information (Singapore); Kuzma, Jennifer, E-mail: jkuzma@ncsu.edu [North Carolina State University, Genetic Engineering & Society Center (United States)

    2015-07-15

    Emerging technologies applied to food products often evoke controversy about their safety and whether to label foods resulting from their use. As such, it is important to understand the factors that influence consumer desires for labeling and their willingness-to-buy (WTB) these food products. Using data from a national survey with US consumers, this study employs structural equation modeling to explore relationships between potential influences such as trust in government to manage technologies, views on restrictive government policies, perceptions about risks and benefits, and preferences for labeling on consumer’s WTB genetically modified (GM) and nano-food products. Some interesting similarities and differences between GM- and nano-food emerged. For both technologies, trust in governing agencies to manage technologies did not influence labeling preferences, but it did influence attitudes about the food technologies themselves. Attitudes toward the two technologies, as measured by risk–benefit comparisons and comfort with consumption, also greatly influenced views of government restrictive policies, labeling preferences, and WTB GM or nano-food products. For differences, labeling preferences were found to influence WTB nano-foods, but not WTB GM foods. Gender and religiosity also had varying effects on WTB and labeling preferences: while gender and religiosity influenced labeling preferences and WTB for GM foods, they did not have a significant influence for nano-foods. We propose some reasons for these differences, such as greater media attention and other heuristics such as value-based concerns about “modifying life” with GM foods. The results of this study can help to inform policies and communication about the application of these new technologies in food products.

  9. A Comparison of the Effects of Three GM Corn Varieties on Mammalian Health

    Directory of Open Access Journals (Sweden)

    Joël Spiroux de Vendômois, François Roullier, Dominique Cellier, Gilles-Eric Séralini

    2009-01-01

    Full Text Available We present for the first time a comparative analysis of blood and organ system data from trials with rats fed three main commercialized genetically modified (GM maize (NK 603, MON 810, MON 863, which are present in food and feed in the world. NK 603 has been modified to be tolerant to the broad spectrum herbicide Roundup and thus contains residues of this formulation. MON 810 and MON 863 are engineered to synthesize two different Bt toxins used as insecticides. Approximately 60 different biochemical parameters were classified per organ and measured in serum and urine after 5 and 14 weeks of feeding. GM maize-fed rats were compared first to their respective isogenic or parental non-GM equivalent control groups. This was followed by comparison to six reference groups, which had consumed various other non-GM maize varieties. We applied nonparametric methods, including multiple pairwise comparisons with a False Discovery Rate approach. Principal Component Analysis allowed the investigation of scattering of different factors (sex, weeks of feeding, diet, dose and group. Our analysis clearly reveals for the 3 GMOs new side effects linked with GM maize consumption, which were sex- and often dose-dependent. Effects were mostly associated with the kidney and liver, the dietary detoxifying organs, although different between the 3 GMOs. Other effects were also noticed in the heart, adrenal glands, spleen and haematopoietic system. We conclude that these data highlight signs of hepatorenal toxicity, possibly due to the new pesticides specific to each GM corn. In addition, unintended direct or indirect metabolic consequences of the genetic modification cannot be excluded.

  10. 大豆GmNAC73-like基因的克隆和表达及其对GmIFS2基因的影响%Cloning and expression of GmNAC73-like gene from Glycine max and its effect on GmIFS2 gene

    Institute of Scientific and Technical Information of China (English)

    万群; 刘晓庆; 张大勇; 何晓兰; 徐照龙; 宁丽华; 黄益洪; 邵宏波

    2016-01-01

    为研究NAC转录因子对大豆﹝Glycine max ( Linn.) Merr.〕异黄酮合成的影响,根据大豆基因组序列设计引物,从豆荚中克隆获得GmNAC73-like基因,并对该基因序列进行生物信息学分析。结果显示:GmNAC73-like基因包含1个长度981 bp的完整开放阅读框,编码326个氨基酸。 GmNAC73-like蛋白的理论相对分子质量37000,理论等电点pI 6.4,为亲水性蛋白,无信号肽,并被定位在细胞核上,包含核定位信号“PKRRK”。同源性比对结果显示:GmNAC73-like蛋白与野大豆( Glycine soja Sieb. et Zucc.)、蒺藜苜蓿( Medicago truncatula Gaertn.)、可可( Theobroma cacao Linn.)、葡萄( Vitis vinifera Linn.)及拟南芥﹝Arabidopsis thaliana ( Linn.) Heynh.〕的NAC蛋白具有较高的相似性,相似度分别为93%、69%、73%、75%和58%。在NJ系统树上,GmNAC73-like蛋白与野大豆的GsNAC8蛋白和木豆﹝Cajanus cajan ( Linn.) Millsp.〕的CcNAC8蛋白聚在一起,显示出较近的亲缘关系。半定量RT-PCR分析结果显示:在大豆的三叶期、开花期和结荚期,GmNAC73-like基因在根中均不表达,在茎和叶中可不同程度表达且茎中表达量较高;而在开花期或结荚期,该基因在花或豆荚中也可表达,且豆荚中表达量较高。酵母单杂交实验结果显示:GmNAC73-like可与异黄酮生物合成关键酶基因GmIFS2启动子中的CGTG基序结合;在大豆转基因发状根系中过表达GmNAC73-like基因后,除查尔酮异构酶基因的表达量无变化外,其他异黄酮生物合成相关基因的表达量均不同程度提高,其中,肉桂酸-4-羟化酶基因和查尔酮合酶基因的表达量明显提高。此外,在GmNAC73-like基因过表达的大豆转基因发状根系中总异黄酮含量显著降低。综合分析结果表明:GmNAC73-like可能通过与MYB转录因子的互作调控GmIFS2基因的表达,并在大豆异黄酮的生物合成过程中起负调控作用。%In order to study the effect of

  11. THE PROCESS OF ADMINISTRATION OF THE UNIVERSITY EXTENSION OF THE UNIVERSITY INSTITUTE OF TECHNOLOGY DR. DOLPHIN MENDOZA IN THE MUNICIPALITY TUCUPITA, STATE DELTA AMACURO / EL PROCESO DE GESTIÓN DE LA EXTENSIÓN UNIVERSITARIA DEL INSTITUTO UNIVERSITARIO DE TECNOLOGÍA DR. DELFÍN MENDOZA EN EL MUNICIPIO TUCUPITA, ESTADO DELTA AMACURO

    Directory of Open Access Journals (Sweden)

    Wilman del Valle Gómez

    2013-06-01

    Full Text Available The university extension as essential function of the university is sustained in its relationships with the community intra and extrauniversity, contributing to its transformation and to improve the quality of life of its members. In the University Institute of Technology Dr. Defín Mendoza, a problem is presented in the administration of this process for what intends to elaborate a strategy for he to strengthen the process of university extension, like part of fomenting a wider cultural system. In this way it will put on the institution to the service of the non alone community from inside its but also using the approaches that the university institutions are to the service of the Venezuelan population's economic, social and cultural development.

  12. Patrones fenológicos de la Provincia de Mendoza, Argentina, mediante serie temporal de imágenes NOAA-AVHRR NDVI GAC Phenological patterns of the province of Mendoza, Argentina, through a temporal series of NOAA-AVHRR NDVI GAC images

    Directory of Open Access Journals (Sweden)

    M. M González Loyarte

    2010-12-01

    Full Text Available Se describe la dinámica temporal de la vegetación de Mendoza mediante análisis de la fenología foliar regional con una serie de 108 imágenes mensuales de índice de vegetación NOAA-AVHRR NDVI GAC. La serie se descompone aplicando la Transformada Rápida de Fourier en parámetros dinámicos: NDVI medio, amplitudes (máxima variabilidad del NDVI y fases (tiempo entre inicio del ciclo y máximo NDVI para diferentes períodos. Con los parámetros con mayor información (variablilidad inter e intraanual se hace una clasificación y se obtiene un mapa de 18 áreas de comportamiento fenológico. Éste se vincula con los ecosistemas y con las unidades de vegetación. Se modela el patrón fenológico (curva NDVI mensual para 17 unidades de vegetación. El mapa aporta elementos dinámicos al estudio regional de la vegetación generando una zonificación nueva explicada por variables que determinan la actividad vegetativa. El patrón fenológico describe el funcionamiento de la vegetación y permite comprender sus variaciones geográficas. El conjunto de la vegetación de Mendoza responde a un ciclo anual con matices localizados de ligera bimodalidad. Los patrones de bajo contraste invierno-verano corresponden a condiciones climáticas xéricas expresando su máximo vegetativo al final del verano; la disponibilidad hídrica incrementa este contraste acortando el tiempo de máxima expresión vegetativa.The temporal dynamics of vegetation in Mendoza is described through analysis of regional foliar phenology using a series of 108 monthly NOAA-AVHRR NDVI GAC images. A Fast Fourier Transform was used to decompose the series into dynamic parameters: mean NDVI, amplitudes (maximum NDVI variability and phases (time from start of cycle to maximum NDVI for different time periods. A classification is made based on those parameters with larger information content (inter- and intra-annual variability, achieving a map of 18 areas of phenological behaviour. This

  13. Morfometría de la escarpa de falla histórica identificada al norte del cerro La Cal, zona de falla La Cal, Mendoza Morphometry of the historic fault scarp identfied north of Cerro La Cal, La Cal Fault Zone, Mendoza

    Directory of Open Access Journals (Sweden)

    F. Mingorance

    2006-12-01

    Full Text Available Investigación morfométrica y paleosísmica histórica fue llevada a cabo en el Norte de Mendoza con el objeto de caracterizar y cuantificar a las evidencias geomorfológicas de ruptura superficial histórica identificadas en el sector septentrional de la zona de falla La Cal. Integración e interpretación de datos e información científica multidisciplinaria, sugieren fuertemente que la ruptura superficial histórica identificada estuvo asociada al terremoto destructivo de Mendoza ocurrido en 1861. La deformación superficial histórica ocurrió casi en su totalidad a lo largo de una escarpa prehistórica previa, mediante una combinación de fallamiento de corrimiento y plegamiento cercano a la superficie. Dos elementos de pendiente históricos de bajo relieve fueron reconocidos en la escarpa compuesta Villavicencio Sur, los cuales se diferencian de la típica secuencia de formas desarrollada en escarpas de falla normal históricas. El "remanente de cara libre", el elemento de pendiente superior, y la "pendiente de colapso", el elemento inferior, son controlados por la fricción interna y por la gravedad y la fricción de deslizamiento del material aluvial, respectivamente. La metodología paleosísmica histórica discutida en este trabajo, parece ser particularmente útil en el período de tiempo que cubre la mayor parte del registro histórico de terremotos destructivos en Argentina, los pasados 350 años, lapso en el cual la mayoría de los métodos de datación absoluta no son muy efectivos.Morphometric and historic paleoseismic research was conducted in northern Mendoza in order to characterize and quantify the geomorphic evidences of historic surface rupture identified on the northern part of the La Cal fault zone. Integration and interpretation of multidisciplinary data and information strongly suggest that the identified historic surface rupture was associated with the devastating Mendoza Earthquake occurred in 1861. The historic

  14. Effect of G/M ratio on the radiation-induced degradation of sodium alginate

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Murat, E-mail: msen@hacettepe.edu.t [Hacettepe University, Department of Chemistry, Beytepe 06800, Ankara (Turkey); Rendevski, Stojan [Institute of Physics, Faculty of Natural Sciences and Mathematics, University ' Ss. Cyril and Methodius' , Gazi Baba, bb., Skopje (Macedonia, The Former Yugoslav Republic of); Kavakli, Pinar Akkas; Sepehrianazar, Amir [Hacettepe University, Department of Chemistry, Beytepe 06800, Ankara (Turkey)

    2010-03-15

    Radiation-induced degradation of sodium alginate (NaAlg) having different G/M ratios was investigated. NaAlg samples were irradiated with gamma rays in air at ambient temperature in the solid state at low dose rate. Change in their molecular weights was followed by size exclusion chromatography (SEC). Changes in their rheological properties and viscosity values as a function of temperature, shear rate and irradiation dose were also determined. Chain scission yields, G(S), and degradation rates were calculated. It was observed that G/M ratio was an important factor controlling the G(S) and degradation rate of sodium alginate.

  15. Effect of G/M ratio on the radiation-induced degradation of sodium alginate

    Science.gov (United States)

    Şen, Murat; Rendevski, Stojan; Kavaklı, Pınar Akkaş; Sepehrianazar, Amir

    2010-03-01

    Radiation-induced degradation of sodium alginate (NaAlg) having different G/M ratios was investigated. NaAlg samples were irradiated with gamma rays in air at ambient temperature in the solid state at low dose rate. Change in their molecular weights was followed by size exclusion chromatography (SEC). Changes in their rheological properties and viscosity values as a function of temperature, shear rate and irradiation dose were also determined. Chain scission yields, G( S), and degradation rates were calculated. It was observed that G/M ratio was an important factor controlling the G( S) and degradation rate of sodium alginate.

  16. Design of an improved high cooling power 4 K GM cryocooler and helium compressor

    Science.gov (United States)

    Hao, X. H.

    2015-12-01

    High cooling power 4 K cryocoolers are in high demand given their broad applications in such fields as magnetic resonance imaging (MRI) and low temperature superconductors. ARS has recently designed and developed a high cooling power 4 K pneumatic-drive GM cryocooler which achieves a typical cooling power of 1.75 W/4.2 K. Steady input power of our newly developed helium compressor supplied to the cold head is 11.8 kW at 60 Hz. The operational speed of the cold head is 30 RPM. The effects of geometries and operational conditions on the cooling performance of this 4 K GM cryocooler are also experimentally tested.

  17. Responding to Expert Arguments. Emerging Lay Topoi in Focus Group Interviews on GM-Crops

    DEFF Research Database (Denmark)

    Horsbøl, Anders

    2009-01-01

    interaction (Myers 2004), in casu in focus groups interviews with both GM-experts and lay persons without specific knowledge on GM-crops. The paper analyses the lay persons' responses to persuasive expert utterances as inventive contributions to the discussion, not just as reactions showing either support...... or rejection. That is, the paper analyses the topoi, the argumentative ‘places', realized by the lay persons in dealing with and making sense of the new knowledge presented by the experts. Finally, the paper identifies the social identities as participants in a public debate, which are enacted by the lay...

  18. Continents divided: Understanding differences between Europe and North America in acceptance of GM crops.

    Science.gov (United States)

    Zilberman, David; Kaplan, Scott; Kim, Eunice; Hochman, Gal; Graff, Gregory

    2013-01-01

    The differences between GM policies in the US and Europe have several causes. GM technology holds a home court advantage in the US and European chemical companies did not support its introduction. The technology did not seem to provide benefits to consumers, and the crops it applied to were not so significant in Europe. The technology was introduced during a time when the political influence of green parties in Europe was especially significant, and European trust of government capacity to enter food security issues was at its lowest.

  19. Pathogen-induced binding of the soybean zinc finger homeodomain proteins GmZF-HD1 and GmZF-HD2 to two repeats of ATTA homeodomain binding site in the calmodulin isoform 4 (GmCaM4) promoter.

    Science.gov (United States)

    Park, Hyeong Cheol; Kim, Man Lyang; Lee, Sang Min; Bahk, Jeong Dong; Yun, Dae-Jin; Lim, Chae Oh; Hong, Jong Chan; Lee, Sang Yeol; Cho, Moo Je; Chung, Woo Sik

    2007-01-01

    Calmodulin (CaM) is involved in defense responses in plants. In soybean (Glycine max), transcription of calmodulin isoform 4 (GmCaM4) is rapidly induced within 30 min after pathogen stimulation, but regulation of the GmCaM4 gene in response to pathogen is poorly understood. Here, we used the yeast one-hybrid system to isolate two cDNA clones encoding proteins that bind to a 30-nt A/T-rich sequence in the GmCaM4 promoter, a region that contains two repeats of a conserved homeodomain binding site, ATTA. The two proteins, GmZF-HD1 and GmZF-HD2, belong to the zinc finger homeodomain (ZF-HD) transcription factor family. Domain deletion analysis showed that a homeodomain motif can bind to the 30-nt GmCaM4 promoter sequence, whereas the two zinc finger domains cannot. Critically, the formation of super-shifted complexes by an anti-GmZF-HD1 antibody incubated with nuclear extracts from pathogen-treated cells suggests that the interaction between GmZF-HD1 and two homeodomain binding site repeats is regulated by pathogen stimulation. Finally, a transient expression assay with Arabidopsis protoplasts confirmed that GmZF-HD1 can activate the expression of GmCaM4 by specifically interacting with the two repeats. These results suggest that the GmZF-HD1 and -2 proteins function as ZF-HD transcription factors to activate GmCaM4 gene expression in response to pathogen.

  20. 小鼠GM-CSF基因的扩增及在HEK293T细胞中的分泌表达%Amplification of mouse GM-CSF gene and its expression in HEK293T cells

    Institute of Scientific and Technical Information of China (English)

    李楠; 张峰; 仲飞

    2012-01-01

    粒细胞-巨噬细胞集落刺激因子( GM-CSF)是机体免疫系统的重要细胞因子,具有生物佐剂作用,为研究GM-CSF的生物佐剂作用,本试验通过RT-PCR方法从小鼠脾脏细胞中扩增小鼠GM-CSF的cDNA,并将其插入到pcDNA3.1质粒中,构建成GM-CSF真核表达载体pcDNA3.1-GMCSF,并在真核细胞进行了瞬时表达.结果表明,本研究扩增的小鼠GM-CSF基因序列与GenBank序列完全一致,表达载体经脂质体介导转染HEK293T细胞,表达产物经western-blot检测,证明GM-CSF能够在HEK293T细胞中进行分泌表达.这为今后研究GM-CSF在动物疫苗,特别是DNA疫苗中的生物佐剂作用创造了必要的条件.%Granulocyte and macrophage colony-stimulating factor (GM-CSF) is an important cy-tokine in animal immune system and is also a biological adjuvant. To express GM-CSF in a secretory manner in eukaryotic cells, the mouse GM-CSF cDNA was amplified with RT-PCR from mouse spleen and was inserted into pcDNA3. 1A expression vector to construct its eukaryotic expression vector, pcDNA3. 1-GMCSF. The transient expression of GM-CSF was performed in HEK293T cells transfected via liposome mediation. The results showed that the amplified GM-CSF gene sequence was consistent with that published in GenBank. The recombi-nant mouse GM-CSF was detected by Western-blot in the culture medium of the transfected HEK293T cells, which indicates that the GM-CSF gene could be expressed and secreted in the cells. Those results provide the necessary conditions for further study on the GM-CSF adjuvant functions in animal vaccine, especially in animal DNA vaccine.