WorldWideScience

Sample records for brain architecture knowledge

  1. Architecture and Workflow of Medical Knowledge Repository

    Science.gov (United States)

    Choi, Hyunsook; Kim, Jeong Ah; Cho, Insook

    Recently, clinical field builds various forms of computerized medical knowledge and tries to use it efficiently. In general, to build and reuse knowledge easily, it is needed to build a knowledge repository. Especially, the credibility of knowledge is important in clinical domain. This paper proposes methods for supporting it. To perform it systematically, we propose the method of the knowledge management processes. The methods for knowledge management can serve equal quality, usability and credibility of knowledge. Knowledge management methods consist of 2 methods. They are the knowledge management processes and the specification of the management targets. And this paper proposes the requirement of a knowledge repository and the architecture of the knowledge repository.

  2. Brain architecture: a design for natural computation.

    Science.gov (United States)

    Kaiser, Marcus

    2007-12-15

    Fifty years ago, John von Neumann compared the architecture of the brain with that of the computers he invented and which are still in use today. In those days, the organization of computers was based on concepts of brain organization. Here, we give an update on current results on the global organization of neural systems. For neural systems, we outline how the spatial and topological architecture of neuronal and cortical networks facilitates robustness against failures, fast processing and balanced network activation. Finally, we discuss mechanisms of self-organization for such architectures. After all, the organization of the brain might again inspire computer architecture. PMID:17855223

  3. Knowledge Building in Landscape Architecture

    OpenAIRE

    Fetzer, Ellen

    2014-01-01

    The objective of this study was to develop an internet-based seminar framework applicable for landscape architecture education. This process was accompanied by various aims. The basic expectation was to keep the main characteristics of landscape architecture education also in the online format. On top of that, four further objectives were anticipated: (1) training of competences for virtual team work, (2) fostering intercultural competence, (3) creation of equal opportunities for education th...

  4. Architectural Knowledge. Transformations, transpositions and variations

    OpenAIRE

    Pacheco, Mónica

    2013-01-01

    The challenge of architecture is to focus on architecture itself — buildings, drawings, and models— as its locus of knowledge and, specifically, on how that knowledge can became a tool of the design process. One of the first attempts to do so, Précis and Recueil, appeared in the early nineteenth century elaborated by Durand. They represented the hinge for an epistemological validation of the discipline, taking further the Vitruvian axiom architectura est sciencia, and answering Enlightenme...

  5. How architecture students gain and apply knowledge of sustainable architecture

    DEFF Research Database (Denmark)

    Donovan, Elizabeth; Holder, Anna

    2016-01-01

    This paper will reflect on understandings of architectural pedagogy and the integration of sustainability into architectural design education. This is framed within an understanding of the construction industry’s role in the production of waste. Despite the complexity of global environmental crises......, architectural educators have the opportunity to do more to address this. We begin with a discussion of contemporary literature and policy concerning education for sustainability in architecture, articulating the particular approaches in development within higher education. This is then compared with critical...... understandings of how architects synthesise different types of knowledge while designing, raising questions about the ‘match’ between educational experiences and subsequent behaviours in practice. Taking an example from Denmark, we outline the approach of Aarhus School of Architecture, where sustainability...

  6. Knowledge Framework Implementation with Multiple Architectures - 13090

    International Nuclear Information System (INIS)

    Multiple kinds of knowledge management systems are operational in public and private enterprises, large and small organizations with a variety of business models that make the design, implementation and operation of integrated knowledge systems very difficult. In recent days, there has been a sweeping advancement in the information technology area, leading to the development of sophisticated frameworks and architectures. These platforms need to be used for the development of integrated knowledge management systems which provides a common platform for sharing knowledge across the enterprise, thereby reducing the operational inefficiencies and delivering cost savings. This paper discusses the knowledge framework and architecture that can be used for the system development and its application to real life need of nuclear industry. A case study of deactivation and decommissioning (D and D) is discussed with the Knowledge Management Information Tool platform and framework. D and D work is a high priority activity across the Department of Energy (DOE) complex. Subject matter specialists (SMS) associated with DOE sites, the Energy Facility Contractors Group (EFCOG) and the D and D community have gained extensive knowledge and experience over the years in the cleanup of the legacy waste from the Manhattan Project. To prevent the D and D knowledge and expertise from being lost over time from the evolving and aging workforce, DOE and the Applied Research Center (ARC) at Florida International University (FIU) proposed to capture and maintain this valuable information in a universally available and easily usable system. (authors)

  7. Architectural Design and the Brain

    DEFF Research Database (Denmark)

    Vartanian, Oshin; Navarrete, Gorka; Chatterjee, Anjan;

    2015-01-01

    We examined the effects of ceiling height and perceived enclosure—defined as perceived visual and locomotive permeability—on aesthetic judgments and approach-avoidance decisions in architectural design. Furthermore, to gain traction on the mechanisms driving the observed effects, we employed func...

  8. Knowledge of Traumatic Brain Injury among Educators

    Science.gov (United States)

    Ernst, William J.; Gallo, Adrienne B.; Sellers, Amanda L.; Mulrine, Jessica; MacNamara, Luciana; Abrahamson, Allison; Kneavel, Meredith

    2016-01-01

    The purpose of this study is to determine knowledge of traumatic brain injury among educators. Few studies have examined knowledge of traumatic brain injury in this population and fewer still have included a substantial proportion of general education teachers. Examining knowledge of traumatic brain injury in educators is important as the vast…

  9. Workshop on SHAring and Reusing architectural Knowledge (SHARK 2011)

    NARCIS (Netherlands)

    Avgeriou, Paris; Lago, Patricia; Kruchten, Philippe

    2011-01-01

    Architectural Knowledge (AK) is defined as the integrated representation of the software architecture of a software-intensive system or family of systems along with architectural decisions and their rationale, external influence and the development environment. The SHARK workshop series focuses on c

  10. SW Architecture for Access to Medical Information for Knowledge Execution

    Science.gov (United States)

    Kim, Suntae; Shim, Bingu; Kim, Jeong Ah; Cho, Insook

    Recently, many approaches have been studied to author medical knowledge and verify doctor's diagnosis based on the specified knowledge. During the verification, intensive access to medical information is unavoidable. Also, the access approach should consider modifiability in order to cover diverse medical information from the variety of hospitals. This paper presents an approach to generating query language from medical knowledge, and shows software architecture for accessing medical information from hospitals by executing generated query languages. Implementation of this architecture has been deployed in a hospital of South Korea so that it shows the feasibility of the architecture.

  11. Bridging: The Spatial Construction of Knowledge in Architectural Research

    Directory of Open Access Journals (Sweden)

    Klaske Havik

    2014-08-01

    Full Text Available This contribution proposes an interdisciplinary approach to architectural research, and states that composition is a methodological act of research. It will first argue that architectural research and practice can gain from a multi-perspectival approach, bringing in knowledge from different fields – in this case the field of literature.Referring to the author’s recently finished dissertation, it proposes a literary approach to architecture and the city, and explains how the ambiguities of architecture (subject-object, author-user and reality-fiction can be addressed by literary means. Then, it makes clear that bringing together knowledge from different fields requires an act of composition. It argues that knowledge can be seen as a spatial construction rather than a linear one, and that the mediating capacity of the architect offers researchers with a background in architecture the possibility to develop such spatial research compositions.

  12. Bridging: The Spatial Construction of Knowledge in Architectural Research

    OpenAIRE

    Klaske Havik

    2012-01-01

    This contribution proposes an interdisciplinary approach to architectural research, and states that composition is a methodological act of research. It will first argue that architectural research and practice can gain from a multi-perspectival approach, bringing in knowledge from different fields – in this case the field of literature.Referring to the author’s recently finished dissertation, it proposes a literary approach to architecture and the city, and explains how the ambiguities of arc...

  13. Versus. Heritage for tomorrow. Vernacular Knowledge for Sustainable Architecture

    OpenAIRE

    Correia, Mariana; Dipasquale, Letizia; Mecca, Saverio

    2014-01-01

    Vernacular architecture represents a great resource that has considerable potential to define principles for sustainable design and contemporary architecture. Traditional architecture and its methods and strategies are undervalued and unemployed in new construction. Nevertheless, very important princi- ples and components can be learned from this heritage, to be applied nowadays, in sustainable archi- tecture. The project’sVerSus main aim is to gain knowledge from the fundamental lessons ...

  14. An Architecture for Context-Aware Knowledge Flow Management Systems

    CERN Document Server

    Jarrahi, Ali

    2012-01-01

    The organizational knowledge is one of the most important and valuable assets of organizations. In such environment, organizations with broad, specialized and up-to-date knowledge, adequately using knowledge resources, will be more successful than their competitors. For effective use of knowledge, dynamic knowledge flow from the sources to destinations is essential. In this regard, a novel complex concept in knowledge management is the analysis, design and implementation of knowledge flow management systems. One of the major challenges in such systems is to explore the knowledge flow from the source to the recipient and control the flow for quality improvements concerning the users' needs as possible. Therefore, the purpose of this paper is to provide an architecture in order to solve this challenge. For this purpose, in addition to the architecture for knowledge flow management systems, a new node selection strategy is provided with higher success rate compared to previous strategies.

  15. A New Architecture for Email Knowledge Extraction

    Directory of Open Access Journals (Sweden)

    Majdi Beseiso

    2012-08-01

    Full Text Available The Semantic Web was designed to represent the enormous data that is existing on the World Wide Web ina machine readable format. The research shows the long period of time that was spent on the Emails forcommunication and information exchange. Adding the semantics to the existing Email systems could not only provide for the valuable usage of time and resources, but also refreshes the meaning of Email communication. The presented research work examines the ontology extraction process from the Email systems adopting scalable pattern rules that is based on the extracted techniques. The proposed architecture is designed to handle the unstructured Emails and the ontologies that are extracted from the Email which is divided into four main components as follows: the Ontology Learning Component, the Management Component, the Semantic Email Component and the Client Side Plugin.

  16. Knowledge Base Grid: A Generic Grid Architecture for Semantic Web

    Institute of Scientific and Technical Information of China (English)

    WU ZhaoHui(吴朝晖); CHEN HuaJun(陈华钧); XU JieFeng(徐杰锋)

    2003-01-01

    The emergence of semantic web will result in an enormous amount of knowledge base resources on the web. In this paper, a generic Knowledge Base Grid Architecture (KB-Grid)for building large-scale knowledge systems on the semantic web is presented. KB-Grid suggests a paradigm that emphasizes how to organize, discover, utilize, and manage web knowledge base resources. Four principal components are under development: a semantic browser for retrieving and browsing semantically enriched information, a knowledge server acting as the web container for knowledge, an ontology server for managing web ontologies, and a knowledge base directory server acting as the registry and catalog of KBs. Also a referential model of knowledge service and the mechanisms required for semantic communication within KB-Grid are defined. To verify the design rationale underlying the KB-Grid, an implementation of Traditional Chinese Medicine(TCM) is described.

  17. Introducing tool support for managing architectural knowledge: an experienced report, engineering computer based systems

    OpenAIRE

    Ali Babar, Muhammad; Northway, Andrew; Gorton, Ian; Heuer, Paul; Nguyen, Thong

    2008-01-01

    Management of software architecture knowledge is vital for improving an organisation???s architectural capabilities. Despite the recognition of the importance of capturing and reusing software architecture knowledge, there is currently no suitable support mechanism available. To address this issue, we have developed a conceptual framework for managing architecture design knowledge. A web-based knowledge management tool, Process-based Architecture Knowledge Management Environment (PAKME), has ...

  18. When Open Architecture Beats Closed: The Entrepreneurial Use of Architectural Knowledge

    OpenAIRE

    Baldwin, Carliss Y.

    2010-01-01

    This paper describes how entrepreneurial firms can use superior architectural knowledge to open up a technical system to gain strategic advantage. The strategy involves, first, identifying "bottlenecks" in the existing system, and then creating a new open architecture that isolates the bottlenecks in modules and allows others to connect to the system at key interfaces. An entrepreneurial firm with limited financial resources can then focus on supplying superior bottleneck modules, and while o...

  19. Ontology management in a service-oriented architecture: Architecture of an knowledge base access service

    OpenAIRE

    Moßgraber, Jürgen; Rospocher, M.

    2012-01-01

    An increasing number of information systems integrate semantic data stores for managing ontologies. To access these knowledge bases most of the available implementations provide application programming interfaces (APIs). The implementations of these APIs normally do not support any kind of network protocol or service interface. This works fine as long as a monolithic system is developed. If the need arises to integrate such a knowledge base into a service-oriented architecture a different app...

  20. Balanced Neural Architecture and the Idling Brain

    Directory of Open Access Journals (Sweden)

    Brent eDoiron

    2014-05-01

    Full Text Available A signature feature of cortical spike trains is their trial-to-trial variability. This variability is large in spontaneous conditions and is reduced when cortex is driven by a stimulus or task. Models of recurrent cortical networks with unstructured, yet balanced, excitation and inhibition generate variability consistent with evoked conditions. However, these models lack the long timescale fluctuations and large variability present in spontaneous conditions. We propose that global network architectures which support a large number of stable states (attractor networks allow balanced networks to capture key features of neural variability in both spontaneous and evoked conditions. We illustrate this using balanced spiking networks with clustered assembly, feedforward chain, and ring structures. By assuming that global network structure is related to stimulus preference, we show that signal correlations are related to the magnitude of correlations in the spontaneous state. In our models, the dynamics of spontaneous activity encompasses much of the possible evoked states, consistent with many experimental reports. Finally, we contrast the impact of stimulation on the trial-to-trial variability in attractor networks with that of strongly coupled spiking networks with chaotic firing rate instabilities, recently investigated by Ostojic (2014. We find that only attractor networks replicate an experimentally observed stimulus-induced quenching of trial-to-trial variability. In total, the comparison of the trial-variable dynamics of single neurons or neuron pairs during spontaneous and evoked activity can be a window into the global structure of balanced cortical networks.

  1. The AI Bus architecture for distributed knowledge-based systems

    Science.gov (United States)

    Schultz, Roger D.; Stobie, Iain

    1991-01-01

    The AI Bus architecture is layered, distributed object oriented framework developed to support the requirements of advanced technology programs for an order of magnitude improvement in software costs. The consequent need for highly autonomous computer systems, adaptable to new technology advances over a long lifespan, led to the design of an open architecture and toolbox for building large scale, robust, production quality systems. The AI Bus accommodates a mix of knowledge based and conventional components, running on heterogeneous, distributed real world and testbed environment. The concepts and design is described of the AI Bus architecture and its current implementation status as a Unix C++ library or reusable objects. Each high level semiautonomous agent process consists of a number of knowledge sources together with interagent communication mechanisms based on shared blackboards and message passing acquaintances. Standard interfaces and protocols are followed for combining and validating subsystems. Dynamic probes or demons provide an event driven means for providing active objects with shared access to resources, and each other, while not violating their security.

  2. The Circuit Architecture of Whole Brains at the Mesoscopic Scale

    OpenAIRE

    Mitra, Partha P.

    2014-01-01

    Vertebrate brains of even moderate size are composed of astronomically large numbers of neurons and show a great degree of individual variability at the microscopic scale. This variation is presumably the result of phenotypic plasticity and individual experience. At a larger scale, however, relatively stable species-typical spatial patterns are observed in neuronal architecture, e.g., the spatial distributions of somata and axonal projection patterns, probably the result of a genetically enco...

  3. The modular and integrative functional architecture of the human brain.

    Science.gov (United States)

    Bertolero, Maxwell A; Yeo, B T Thomas; D'Esposito, Mark

    2015-12-01

    Network-based analyses of brain imaging data consistently reveal distinct modules and connector nodes with diverse global connectivity across the modules. How discrete the functions of modules are, how dependent the computational load of each module is to the other modules' processing, and what the precise role of connector nodes is for between-module communication remains underspecified. Here, we use a network model of the brain derived from resting-state functional MRI (rs-fMRI) data and investigate the modular functional architecture of the human brain by analyzing activity at different types of nodes in the network across 9,208 experiments of 77 cognitive tasks in the BrainMap database. Using an author-topic model of cognitive functions, we find a strong spatial correspondence between the cognitive functions and the network's modules, suggesting that each module performs a discrete cognitive function. Crucially, activity at local nodes within the modules does not increase in tasks that require more cognitive functions, demonstrating the autonomy of modules' functions. However, connector nodes do exhibit increased activity when more cognitive functions are engaged in a task. Moreover, connector nodes are located where brain activity is associated with many different cognitive functions. Connector nodes potentially play a role in between-module communication that maintains the modular function of the brain. Together, these findings provide a network account of the brain's modular yet integrated implementation of cognitive functions. PMID:26598686

  4. Primate brain architecture and selection in relation to sex

    Directory of Open Access Journals (Sweden)

    Nunn Charles L

    2007-05-01

    Full Text Available Abstract Background Social and competitive demands often differ between the sexes in mammals. These differing demands should be expected to produce variation in the relative sizes of various brain structures. Sexual selection on males can be predicted to influence brain components handling sensory-motor skills that are important for physical competition or neural pathways involving aggression. Conversely, because female fitness is more closely linked to ecological factors and social interactions that enable better acquisition of resources, social selection on females should select for brain components important for navigating social networks. Sexual and social selection acting on one sex could produce sexual dimorphism in brain structures, which would result in larger species averages for those same brain structures. Alternatively, sex-specific selection pressures could produce correlated effects in the other sex, resulting in larger brain structures for both males and females of a species. Data are presently unavailable for the sex-specific sizes of brain structures for anthropoid primates, but under either scenario, the effects of sexual and social selection should leave a detectable signal in average sizes of brain structures for different species. Results The degree of male intra-sexual selection was positively correlated with several structures involved in autonomic functions and sensory-motor skills, and in pathways relating to aggression and aggression control. The degree of male intra-sexual selection was not correlated with relative neocortex size, which instead was significantly positively correlated with female social group size, but negatively correlated with male group size. Conclusion Sexual selection on males and social selection on females have exerted different effects on primate brain architecture. Species with a higher degree of male intra-sexual selection carry a neural signature of an evolutionary history centered on

  5. Personality is reflected in the brain's intrinsic functional architecture.

    Directory of Open Access Journals (Sweden)

    Jonathan S Adelstein

    Full Text Available Personality describes persistent human behavioral responses to broad classes of environmental stimuli. Investigating how personality traits are reflected in the brain's functional architecture is challenging, in part due to the difficulty of designing appropriate task probes. Resting-state functional connectivity (RSFC can detect intrinsic activation patterns without relying on any specific task. Here we use RSFC to investigate the neural correlates of the five-factor personality domains. Based on seed regions placed within two cognitive and affective 'hubs' in the brain--the anterior cingulate and precuneus--each domain of personality predicted RSFC with a unique pattern of brain regions. These patterns corresponded with functional subdivisions responsible for cognitive and affective processing such as motivation, empathy and future-oriented thinking. Neuroticism and Extraversion, the two most widely studied of the five constructs, predicted connectivity between seed regions and the dorsomedial prefrontal cortex and lateral paralimbic regions, respectively. These areas are associated with emotional regulation, self-evaluation and reward, consistent with the trait qualities. Personality traits were mostly associated with functional connections that were inconsistently present across participants. This suggests that although a fundamental, core functional architecture is preserved across individuals, variable connections outside of that core encompass the inter-individual differences in personality that motivate diverse responses.

  6. A development architecture for serious games using BCI (brain computer interface) sensors.

    Science.gov (United States)

    Sung, Yunsick; Cho, Kyungeun; Um, Kyhyun

    2012-01-01

    Games that use brainwaves via brain-computer interface (BCI) devices, to improve brain functions are known as BCI serious games. Due to the difficulty of developing BCI serious games, various BCI engines and authoring tools are required, and these reduce the development time and cost. However, it is desirable to reduce the amount of technical knowledge of brain functions and BCI devices needed by game developers. Moreover, a systematic BCI serious game development process is required. In this paper, we present a methodology for the development of BCI serious games. We describe an architecture, authoring tools, and development process of the proposed methodology, and apply it to a game development approach for patients with mild cognitive impairment as an example. This application demonstrates that BCI serious games can be developed on the basis of expert-verified theories. PMID:23202227

  7. The brain's functional network architecture reveals human motives.

    Science.gov (United States)

    Hein, Grit; Morishima, Yosuke; Leiberg, Susanne; Sul, Sunhae; Fehr, Ernst

    2016-03-01

    Goal-directed human behaviors are driven by motives. Motives are, however, purely mental constructs that are not directly observable. Here, we show that the brain's functional network architecture captures information that predicts different motives behind the same altruistic act with high accuracy. In contrast, mere activity in these regions contains no information about motives. Empathy-based altruism is primarily characterized by a positive connectivity from the anterior cingulate cortex (ACC) to the anterior insula (AI), whereas reciprocity-based altruism additionally invokes strong positive connectivity from the AI to the ACC and even stronger positive connectivity from the AI to the ventral striatum. Moreover, predominantly selfish individuals show distinct functional architectures compared to altruists, and they only increase altruistic behavior in response to empathy inductions, but not reciprocity inductions. PMID:26941317

  8. Disrupted Brain Functional Network Architecture in Chronic Tinnitus Patients

    Science.gov (United States)

    Chen, Yu-Chen; Feng, Yuan; Xu, Jin-Jing; Mao, Cun-Nan; Xia, Wenqing; Ren, Jun; Yin, Xindao

    2016-01-01

    Purpose: Resting-state functional magnetic resonance imaging (fMRI) studies have demonstrated the disruptions of multiple brain networks in tinnitus patients. Nonetheless, several studies found no differences in network processing between tinnitus patients and healthy controls (HCs). Its neural bases are poorly understood. To identify aberrant brain network architecture involved in chronic tinnitus, we compared the resting-state fMRI (rs-fMRI) patterns of tinnitus patients and HCs. Materials and Methods: Chronic tinnitus patients (n = 24) with normal hearing thresholds and age-, sex-, education- and hearing threshold-matched HCs (n = 22) participated in the current study and underwent the rs-fMRI scanning. We used degree centrality (DC) to investigate functional connectivity (FC) strength of the whole-brain network and Granger causality to analyze effective connectivity in order to explore directional aspects involved in tinnitus. Results: Compared to HCs, we found significantly increased network centrality in bilateral superior frontal gyrus (SFG). Unidirectionally, the left SFG revealed increased effective connectivity to the left middle orbitofrontal cortex (OFC), left posterior lobe of cerebellum (PLC), left postcentral gyrus, and right middle occipital gyrus (MOG) while the right SFG exhibited enhanced effective connectivity to the right supplementary motor area (SMA). In addition, the effective connectivity from the bilateral SFG to the OFC and SMA showed positive correlations with tinnitus distress. Conclusions: Rs-fMRI provides a new and novel method for identifying aberrant brain network architecture. Chronic tinnitus patients have disrupted FC strength and causal connectivity mostly in non-auditory regions, especially the prefrontal cortex (PFC). The current findings will provide a new perspective for understanding the neuropathophysiological mechanisms in chronic tinnitus. PMID:27458377

  9. Fifth International Workshop on Sharing and Reusing Architectural Knowledge (SHARK 2010)

    NARCIS (Netherlands)

    Lago, Patricia; Avgeriou, Paris; Kruchten, Philippe

    2010-01-01

    Architectural Knowledge (AK) is defined as the integrated representation of the software architecture of a software-intensive system or family of systems along with architectural decisions and their rationale, external influence and the development environment. The SHARK workshop series focuses on c

  10. Application of knowledge-based approaches in software architecture : A systematic mapping study

    NARCIS (Netherlands)

    Li, Zengyang; Liang, Peng; Avgeriou, Paris

    2013-01-01

    Context: Knowledge management technologies have been employed across software engineering activities for more than two decades. Knowledge-based approaches can be used to facilitate software architecting activities (e.g., architectural evaluation). However, there is no comprehensive understanding on

  11. A Development Architecture for Serious Games Using BCI (Brain Computer Interface Sensors

    Directory of Open Access Journals (Sweden)

    Kyhyun Um

    2012-11-01

    Full Text Available Games that use brainwaves via brain–computer interface (BCI devices, to improve brain functions are known as BCI serious games. Due to the difficulty of developing BCI serious games, various BCI engines and authoring tools are required, and these reduce the development time and cost. However, it is desirable to reduce the amount of technical knowledge of brain functions and BCI devices needed by game developers. Moreover, a systematic BCI serious game development process is required. In this paper, we present a methodology for the development of BCI serious games. We describe an architecture, authoring tools, and development process of the proposed methodology, and apply it to a game development approach for patients with mild cognitive impairment as an example. This application demonstrates that BCI serious games can be developed on the basis of expert-verified theories.

  12. An Object-Oriented Software Architecture for the Explorer-2 Knowledge Management Environment

    OpenAIRE

    Tarabar, David B.; Greenes, Robert A; Slosser, Eric T.

    1989-01-01

    Explorer-2 is a workstation based environment to facilitate knowledge management. It provides consistent access to a broad range of knowledge on the basis of purpose, not type. We have developed a software architecture based on Object-Oriented programming for Explorer-2. We have defined three classes of program objects: Knowledge ViewFrames, Knowledge Resources, and Knowledge Bases. This results in knowledge management at three levels: the screen level, the disk level and the meta-knowledge l...

  13. Intelligent open-architecture controller using knowledge server

    Science.gov (United States)

    Nacsa, Janos; Kovacs, George L.; Haidegger, Geza

    2001-12-01

    In an ideal scenario of intelligent machine tools [22] the human mechanist was almost replaced by the controller. During the last decade many efforts have been made to get closer to this ideal scenario, but the way of information processing within the CNC did not change too much. The paper summarizes the requirements of an intelligent CNC evaluating the different research efforts done in this field using different artificial intelligence (AI) methods. The need for open CNC architecture was emerging at many places around the world. The second part of the paper introduces and shortly compares these efforts. In the third part a low cost concept for intelligent and open systems named Knowledge Server for Controllers (KSC) is introduced. It allows more devices to solve their intelligent processing needs using the same server that is capable to process intelligent data. In the final part the KSC concept is used in an open CNC environment to build up some elements of an intelligent CNC. The preliminary results of the implementation are also introduced.

  14. Capturing Tacit Architectural Knowledge Using the Repertory Grid Technique (NIER Track)

    NARCIS (Netherlands)

    Tofan, Dan; Galster, Matthias; Avgeriou, Paris

    2011-01-01

    Knowledge about the architecture of a software-intensive system tends to vaporize easily. This leads to increased maintenance costs. We explore a new idea: utilizing the repertory grid technique to capture tacit architectural knowledge. Particularly, we investigate the elicitation of design decision

  15. Documentation of Software Architecture from a Knowledge Management Perspective - Design Representation

    Science.gov (United States)

    Kruchten, Philippe

    In this chapter we survey how architects have represented architectural knowledge and in particular architectural design. This has evolved over the last 3 decades, from very intuitive and informal, to very structured, abstract and formal, from simple diagrams and metaphors, design notations, and specific languages. As our understanding of architectural knowledge evolved, the importance of design rationale and the decision process became more and more prominent. There is however a constant through this evolution: the systematic use of metaphors.

  16. Cortical network architecture for context processing in primate brain.

    Science.gov (United States)

    Chao, Zenas C; Nagasaka, Yasuo; Fujii, Naotaka

    2015-01-01

    Context is information linked to a situation that can guide behavior. In the brain, context is encoded by sensory processing and can later be retrieved from memory. How context is communicated within the cortical network in sensory and mnemonic forms is unknown due to the lack of methods for high-resolution, brain-wide neuronal recording and analysis. Here, we report the comprehensive architecture of a cortical network for context processing. Using hemisphere-wide, high-density electrocorticography, we measured large-scale neuronal activity from monkeys observing videos of agents interacting in situations with different contexts. We extracted five context-related network structures including a bottom-up network during encoding and, seconds later, cue-dependent retrieval of the same network with the opposite top-down connectivity. These findings show that context is represented in the cortical network as distributed communication structures with dynamic information flows. This study provides a general methodology for recording and analyzing cortical network neuronal communication during cognition. PMID:26416139

  17. A "Knowledge Trading Game" for Collaborative Design Learning in an Architectural Design Studio

    Science.gov (United States)

    Wang, Wan-Ling; Shih, Shen-Guan; Chien, Sheng-Fen

    2010-01-01

    Knowledge-sharing and resource exchange are the key to the success of collaborative design learning. In an architectural design studio, design knowledge entails learning efforts that need to accumulate and recombine dispersed and complementary pieces of knowledge. In this research, firstly, "Knowledge Trading Game" is proposed to be a way for…

  18. An agent architecture with on-line learning of both procedural and declarative knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Sun, R.; Peterson, T.; Merrill, E. [Univ. of Alabama, Tuscaloosa, AL (United States)

    1996-12-31

    In order to develop versatile cognitive agents that learn in situated contexts and generalize resulting knowledge to different environments, we explore the possibility of learning both declarative and procedural knowledge in a hybrid connectionist architecture. The architecture is based on the two-level idea proposed earlier by the author. Declarative knowledge is represented symbolically, while procedural knowledge is represented subsymbolically. The architecture integrates reactive procedures, rules, learning, and decision-making in a unified framework, and structures different learning components (including Q-learning and rule induction) in a synergistic way to perform on-line and integrated learning.

  19. Architecture as Material Discourse : On the spatial formulation of knowledge and ideals in four library extensions

    OpenAIRE

    Koch, Daniel

    2015-01-01

    In recent decades libraries have been challenged in many ways, perhaps most pointedly by the digital revolution. This is, however, not the first time – a series of booms in library architecture emerging rather when knowledge ideals are chal- lenged than established allows us to discuss library architecture more clearly as investigations into what knowledge, learning and literature could be rather than as expressions of what knowledge, learning and literature is. These questions are complex an...

  20. 论知识管理和信息构建%On Knowledge Management & Information Architecture

    Institute of Scientific and Technical Information of China (English)

    张新民; 梁战平

    2003-01-01

    The paper outlines the concept and implementation process of knowledge management, introduces a new domain of study in information science, that is, the concept, composition and process of information architecture, and explores the relationship between knowledge aumagement and information architecture.

  1. Evaluation Research as a Mechanism for Critical Inquiry and Knowledge Construction in Architectural and Urban Education

    OpenAIRE

    Salama, Ashraf M.

    2012-01-01

    This article responds to the misconceptions that continue to characterize the delivery of knowledge content in architectural courses. Based on reviewing the literature on pedagogy the paper explores the value and benefits of introducing evaluation research as a mechanism for critical inquiry and knowledge construction in theory courses in architecture and urbanism. A framework is developed and employed to demonstrate the way in which this type of learning can be incorporated.   The developmen...

  2. "Science" and "Art" in landscape architecture knowledge production

    NARCIS (Netherlands)

    Lenzholzer, S.

    2013-01-01

    Within landscape architecture, two main approaches exist in the discipline- one art and one science related approach. Much criticism arose on outdoor space design that relies on either ‘art’ or ‘science’ approaches. This caused avoidance and underuse of many outdoor spaces. At the basis are two prob

  3. Knowledge Management System Architecture for the Industry Cluster

    OpenAIRE

    Sureephong, Pradorn; Chakpitak, Nopasit; Ouzrout, Yacine; Neubert, Gilles; BOURAS, Abdelaziz

    2007-01-01

    Since the concept of the industry cluster was popularized by Porter in 1990, many countries try to improve the competitiveness through industry sector. Not only companies who take part in the cluster but also academic institutes, government agencies, associations, and supportive industries. The more actors involved in the cluster the more knowledge were distributed among the member of cluster. Although, many literatures about cluster explained how knowledge is important for the cluster develo...

  4. MAS architecture and knowledge model for vehicles data communication

    Directory of Open Access Journals (Sweden)

    René MANDIAU

    2013-07-01

    Full Text Available Normal 0 21 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-ansi-language:EN-US;} Completely autonomous vehicles in traffic should allow to decrease the number of road accident victims greatly, and should allow gains in terms of performance and economy. Modelling the vehicles interaction, and especially knowledge sharing, is one of the main challenges to optimize traffic flow with autonomous vehicles. We propose in this paper a model of knowledge communication between mobile agents on a traffic network. The model of knowledge and of interaction enables to propagate new knowledge without overloading the system with a too large number of communications. For that, only the new knowledge is communicated, and two agents communicate the same knowledge only once. Moreover, in order to allow agents to update their knowledge (perceived or created, a notion of degradation is used. A simulator has been built to evaluate the proposal, before to implement it in mobile robots. Some results of the simulator are proposed in this article.

  5. MAS architecture and knowledge model for vehicles data communication

    Directory of Open Access Journals (Sweden)

    Emmanuel ADAM

    2012-07-01

    Full Text Available Normal 0 21 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Cambria; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-ansi-language:EN-US;} Completely autonomous vehicles in traffic should allow to decrease the number of road accident victims greatly, and should allow gains in terms of performance and economy. Modelling the vehicles interaction, and especially knowledge sharing, is one of the main challenges to optimize traffic flow with autonomous vehicles. We propose in this paper a model of knowledge communication between mobile agents on a traffic network. The model of knowledge and of interaction enables to propagate new knowledge without overloading the system with a too large number of communications. For that, only the new knowledge is communicated, and two agents communicate the same knowledge only once. Moreover, in order to allow agents to update their knowledge (perceived or created, a notion of degradation is used. A simulator has been built to evaluate the proposal, before to implement it in mobile robots. Some results of the simulator are proposed in this article.

  6. Meme media and meme market architectures knowledge media for editing distributing and managing intellectual resources

    CERN Document Server

    Tanaka, Y

    2003-01-01

    "In this book, Yuzuru Tanaka proposes a powerful new paradigm: that knowledge media, or "memes," operate in a way that closely resembles the biological function of genes, with their network publishing repository working as a gene pool to accelerate the evolution of knowledge shared in our societies. In Meme Media and Meme Market Architectures: Knowledge Media for Editing, Distributing, and Managing Intellectual Resources, Tanaka outlines a ready-to-use knowledge media system, supplemented with sample media objects, which allows readers to experience the knowledge media paradigm."--Jacket.

  7. Inquiry and the social : an empirical study of the construction of knowledge in architectural designing

    OpenAIRE

    Berthold, Henning Alexander

    2013-01-01

    This thesis is a study of inquiry. Drawing upon the work of American pragmatist John Dewey, this work seeks to contribute to our understanding of the construction of knowledge within the social system of communities of inquiry. The process of inquiry that is traced in this work is one effected in the course of architectural designing. An ethnographically informed study of an architectural masterplan project is used to illustrate Dewey’s ideas and how they are played out in design practice. Th...

  8. Pattern-based Knowledge Architecture for Information Logistics

    OpenAIRE

    Sandkuhl, Kurt

    2015-01-01

    Accurate and readily available information is a crucial basis for decision making, problem solving, or performing knowledge-intensive work. In networked organizations with geographically distributed work force and processes, like logistics networks or SME-clusters, quickly finding the right information for a given purpose often is a challenge. An improved information supply would contribute significantly to saving time and most likely to improving productivity. The paper aims at contributing ...

  9. When Neuroscience 'Touches' Architecture: From Hapticity to a Supramodal Functioning of the Human Brain.

    Science.gov (United States)

    Papale, Paolo; Chiesi, Leonardo; Rampinini, Alessandra C; Pietrini, Pietro; Ricciardi, Emiliano

    2016-01-01

    In the last decades, the rapid growth of functional brain imaging methodologies allowed cognitive neuroscience to address open questions in philosophy and social sciences. At the same time, novel insights from cognitive neuroscience research have begun to influence various disciplines, leading to a turn to cognition and emotion in the fields of planning and architectural design. Since 2003, the Academy of Neuroscience for Architecture has been supporting 'neuro-architecture' as a way to connect neuroscience and the study of behavioral responses to the built environment. Among the many topics related to multisensory perceptual integration and embodiment, the concept of hapticity was recently introduced, suggesting a pivotal role of tactile perception and haptic imagery in architectural appraisal. Arguments have thus risen in favor of the existence of shared cognitive foundations between hapticity and the supramodal functional architecture of the human brain. Precisely, supramodality refers to the functional feature of defined brain regions to process and represent specific information content in a more abstract way, independently of the sensory modality conveying such information to the brain. Here, we highlight some commonalities and differences between the concepts of hapticity and supramodality according to the distinctive perspectives of architecture and cognitive neuroscience. This comparison and connection between these two different approaches may lead to novel observations in regard to people-environment relationships, and even provide empirical foundations for a renewed evidence-based design theory. PMID:27375542

  10. Knowledge Network Architecture in Support of International Science

    Science.gov (United States)

    Hugo, Wim

    2015-04-01

    ICSU (The International Council for Science) created the World Data System (WDS) as an interdisciplinary body at its General Assembly in Maputo in 2008, and since then the membership of the WDS has grown to include 86 members, of whom 56 are institutions or data centres focused on providing quality-assured data and services to the scientific community. In addition to its objective of providing universal and equitable access to such data and services, WDS is also active in promoting stewardship, standards and conventions, and improved access to products derived from data and services. Whereas WDS is in process of aggregating and harmonizing the meta-data collections of its membership, it is clear that additional benefits can be obtained by supplementing such traditional meta-data sources with information about members, authors, and the coverages of the data, as well as metrics such as citation indices, quality indicators, and usability. Moreover, the relationships between the actors and systems that populate this meta-data landscape can be seen as a knowledge network that describes a sub-set of global scientific endeavor. Such a knowledge network is useful in many ways, supporting both machine-based and human requests for contextual information related to a specific data set, institution, author, topic, or other entities in the network. Specific use cases that can be realised include decision and policy support for funding agencies, identification of collaborators, ranking of data sources, availability of data for specific coverages, and many more. The paper defines the scope of and conceptual background to such a knowledge network, discusses some initial work done by WDS to establish the network, and proposes an implementation model for rapid operationalisation. In this model, established interests such as DataCITE, ORCID, and CrossRef have well-defined roles, and the standards, services, and registries required to build a community-maintained, scalable knowledge

  11. WDS Knowledge Network Architecture in Support of International Science

    Science.gov (United States)

    Mokrane, M.; Minster, J. B. H.; Hugo, W.

    2014-12-01

    ICSU (International Council for Science) created the World Data System (WDS) as an interdisciplinary body at its General Assembly in Maputo in 2008, and since then the membership of the WDS has grown to include 86 members, of whom 56 are institutions or data centers focused on providing quality-assured data and services to the scientific community, and 10 more are entire networks of such data facilities and services. In addition to its objective of providing universal and equitable access to scientific data and services, WDS is also active in promoting stewardship, standards and conventions, and improved access to products derived from data and services. Whereas WDS is in process of aggregating and harmonizing the metadata collections of its membership, it is clear that additional benefits can be obtained by supplementing such traditional metadata sources with information about members, authors, and the coverages of the data, as well as metrics such as citation indices, quality indicators, and usability. Moreover, the relationships between the actors and systems that populate this metadata landscape can be seen as a knowledge network that describes a subset of global scientific endeavor. Such a knowledge network is useful in many ways, supporting both machine-based and human requests for contextual information related to a specific data set, institution, author, topic, or other entities in the network. Specific use cases that can be realized include decision and policy support for funding agencies, identification of collaborators, ranking of data sources, availability of data for specific coverages, and many more. The paper defines the scope of and conceptual background to such a knowledge network, discusses some initial work done by WDS to establish the network, and proposes an implementation model for rapid operationalization. In this model, established interests such as DataCite, ORCID, and CrossRef have well-defined roles, and the standards, services, and

  12. Evaluation Research as a Mechanism for Critical Inquiry and Knowledge Construction in Architectural and Urban Education

    Directory of Open Access Journals (Sweden)

    Ashraf M. Salama

    2012-12-01

    Full Text Available This article responds to the misconceptions that continue to characterize the delivery of knowledge content in architectural courses. Based on reviewing the literature on pedagogy the paper explores the value and benefits of introducing evaluation research as a mechanism for critical inquiry and knowledge construction in theory courses in architecture and urbanism. A framework is developed and employed to demonstrate the way in which this type of learning can be incorporated.   The development and implementation of a series of in-class and off campus exercises in two different contexts reveal that structured actions and experiences help students to be in control over their learning while invigorating their understanding of the body of knowledge delivered in a typical lecture format. It firmly believed that this would offer students multiple learning opportunities while fostering their capabilities to shift from passive listeners to active learners and from knowledge consumers to knowledge producers.

  13. When Neuroscience ‘Touches’ Architecture: From Hapticity to a Supramodal Functioning of the Human Brain

    OpenAIRE

    Papale, Paolo; Chiesi, Leonardo; Rampinini, Alessandra C.; Pietrini, Pietro; Ricciardi, Emiliano

    2016-01-01

    In the last decades, the rapid growth of functional brain imaging methodologies allowed cognitive neuroscience to address open questions in philosophy and social sciences. At the same time, novel insights from cognitive neuroscience research have begun to influence various disciplines, leading to a turn to cognition and emotion in the fields of planning and architectural design. Since 2003, the Academy of Neuroscience for Architecture has been supporting ‘neuro-architecture’ as a way to conne...

  14. BrainFrame: a knowledge visualization system for the neurosciences

    Science.gov (United States)

    Barnes, Steven J.; Shaw, Chris D.

    2009-01-01

    Neuroscience has benefited from an explosion of new experimental techniques; many have only become feasible in the wake of improvements in computing speed and data storage. At the same time, these new computation-intensive techniques have led to a growing gulf between the data and the knowledge extracted from those data. That is, in the neurosciences there is a paucity of effective knowledge management techniques and an accelerating accumulation of experimental data. The purpose of the project described in the present paper is to create a visualization of the knowledge base of the neurosciences. At run-time, this 'BrainFrame' project accesses several web-based ontologies and generates a semantically zoomable representation of any one of many levels of the human nervous system.

  15. When Neuroscience ‘Touches’ Architecture: From Hapticity to a Supramodal Functioning of the Human Brain

    Science.gov (United States)

    Papale, Paolo; Chiesi, Leonardo; Rampinini, Alessandra C.; Pietrini, Pietro; Ricciardi, Emiliano

    2016-01-01

    In the last decades, the rapid growth of functional brain imaging methodologies allowed cognitive neuroscience to address open questions in philosophy and social sciences. At the same time, novel insights from cognitive neuroscience research have begun to influence various disciplines, leading to a turn to cognition and emotion in the fields of planning and architectural design. Since 2003, the Academy of Neuroscience for Architecture has been supporting ‘neuro-architecture’ as a way to connect neuroscience and the study of behavioral responses to the built environment. Among the many topics related to multisensory perceptual integration and embodiment, the concept of hapticity was recently introduced, suggesting a pivotal role of tactile perception and haptic imagery in architectural appraisal. Arguments have thus risen in favor of the existence of shared cognitive foundations between hapticity and the supramodal functional architecture of the human brain. Precisely, supramodality refers to the functional feature of defined brain regions to process and represent specific information content in a more abstract way, independently of the sensory modality conveying such information to the brain. Here, we highlight some commonalities and differences between the concepts of hapticity and supramodality according to the distinctive perspectives of architecture and cognitive neuroscience. This comparison and connection between these two different approaches may lead to novel observations in regard to people–environment relationships, and even provide empirical foundations for a renewed evidence-based design theory.

  16. Involvement of Service Knowledge Management System in Integration of ITIL V3 and Enterprise Architecture

    Directory of Open Access Journals (Sweden)

    Akbar Nabiollahi

    2011-01-01

    Full Text Available Problem statement: This study attempts to investigate and clarify the relationship of Service Knowledge Management System (SKMS with our primary study regard to using enterprise architecture through ITIL V3. Approach: SKMS concepts are introduced by ITIL V3 as a set of tools and databases that are used to manage knowledge and information of IT services. Results: The SKMS stores, retrieves, updates and presents all information that is expected for management of whole lifecycle of IT Services. Primary goal of our research is to provide a comprehensive integrated framework to determine and address IT Service Architecture requirements and related issues in ITIL V3 through using Enterprise Architecture. Conclusion/Recommendations: Through the main process of our study we realized that ITIL Knowledge Management process and its model for SKMS might be good candidates for storing and retrieving architectures of IT services. In other word, SKMS can be used as a set of tools and databases for management of architecture components of our target framework. For next step, the concern is how to develop proposed SKMS.

  17. An Equivalent Architecture of Learner's and Instructor's Knowledge through the Matching of Intended Learning Outcome

    OpenAIRE

    Tangworakitthaworn, Preecha; Gilbert, Lester; Wills, Gary

    2012-01-01

    Constructivism and instructionism, two grounded theories of learning and teaching, are contradiction in terms of practitioner's perspective. This leads to an attempt to bridge the gap between these two theories by designing the balanced approach. In this paper an equivalent architecture of learner’s and instructor’s knowledge is introduced via a matching strategy through the intended learning outcome.

  18. PHENOMENOLOGICAL ARCHITECTURE OF A MIND AND OPERATIONAL ARCHITECTONICS OF THE BRAIN: THE UNIFIED METASTABLE CONTINUUM

    OpenAIRE

    ANDREW A. FINGELKURTS; Fingelkurts, Alexander A.; CARLOS F. H. NEVES

    2009-01-01

    In our contribution we will observe phenomenal architecture of a mind and operational architectonics of the brain and will show their intimate connectedness within a single integrated metastable continuum. The notion of operation of different complexity is the fundamental and central one in bridging the gap between brain and mind: it is precisely by means of this notion that it is possible to identify what at the same time belongs to the phenomenal conscious level and to the neurophysiologica...

  19. Design for a Darwinian Brain: Part 2. Cognitive Architecture

    OpenAIRE

    Fernando, Chrisantha; Vasas, Vera

    2013-01-01

    The accumulation of adaptations in an open-ended manner during lifetime learning is a holy grail in reinforcement learning, intrinsic motivation, artificial curiosity, and developmental robotics. We present a specification for a cognitive architecture that is capable of specifying an unlimited range of behaviors. We then give examples of how it can stochastically explore an interesting space of adjacent possible behaviors. There are two main novelties; the first is a proper definition of the ...

  20. The Study on the Architecture of Public knowledge Service Platform Based on Collaborative Innovation

    Science.gov (United States)

    Hu, Chang Ping; Zhang, Min; Xiang, Fei

    The knowledge service platform is seen as the vital intermediaries in innovation cycle, and for users to locate, exchange and acquire knowledge in a systematic way. It is increasingly recognizing the powerful role that knowledge service platform provide in building a national innovation capacity. The knowledge service platforms in the China's national innovation system, mostly based on the digital libraries, are supported and constructed by diverse departments and systems. These platforms disperse in construction, have respective division and orientation. However, along with the development of information technology and the revolution of innovation model, the requirements for the reconstruction of knowledge service platform in innovation system are brought forward. In this paper, we analyze the resources integration framework of the existing public service platform, and put forward the architecture of the public knowledge service platform based on collaborative innovation; we also discuss its concrete implementation.

  1. A Knowledge-Based System Approach for Extracting Abstractions from Service Oriented Architecture Artifacts

    Directory of Open Access Journals (Sweden)

    George Goehring

    2013-03-01

    Full Text Available Rule-based methods have traditionally been applied to develop knowledge-based systems that replicate expert performance on a deep but narrow problem domain. Knowledge engineers capture expert knowledge and encode it as a set of rules for automating the expert’s reasoning process to solve problems in a variety of domains. We describe the development of a knowledge-based system approach to enhance program comprehension of Service Oriented Architecture (SOA software. Our approach uses rule-based methods to automate the analysis of the set of artifacts involved in building and deploying a SOA composite application. The rules codify expert knowledge to abstract information from these artifacts to facilitate program comprehension and thus assist Software Engineers as they perform system maintenance activities. A main advantage of the knowledge-based approach is its adaptability to the heterogeneous and dynamically evolving nature of SOA environments.

  2. Novel theory of the human brain: information-commutation basis of architecture and principles of operation

    Directory of Open Access Journals (Sweden)

    Bryukhovetskiy AS

    2015-02-01

    Full Text Available Andrey S Bryukhovetskiy Center for Biomedical Technologies, Federal Research and Clinical Center for Specialized Types of Medical Assistance and Medical Technologies of the Federal Medical Biological Agency, NeuroVita Clinic of Interventional and Restorative Neurology and Therapy, Moscow, Russia Abstract: Based on the methodology of the informational approach and research of the genome, proteome, and complete transcriptome profiles of different cells in the nervous tissue of the human brain, the author proposes a new theory of information-commutation organization and architecture of the human brain which is an alternative to the conventional systemic connective morphofunctional paradigm of the brain framework. Informational principles of brain operation are defined: the modular principle, holographic principle, principle of systematicity of vertical commutative connection and complexity of horizontal commutative connection, regulatory principle, relay principle, modulation principle, “illumination” principle, principle of personalized memory and intellect, and principle of low energy consumption. The author demonstrates that the cortex functions only as a switchboard and router of information, while information is processed outside the nervous tissue of the brain in the intermeningeal space. The main structural element of information-commutation in the brain is not the neuron, but information-commutation modules that are subdivided into receiver modules, transmitter modules, and subscriber modules, forming a vertical architecture of nervous tissue in the brain as information lines and information channels, and a horizontal architecture as central, intermediate, and peripheral information-commutation platforms. Information in information-commutation modules is transferred by means of the carriers that are characteristic to the specific information level from inductome to genome, transcriptome, proteome, metabolome, secretome, and magnetome

  3. How the Timing and Quality of Early Experiences Influence the Development of Brain Architecture

    Science.gov (United States)

    Fox, Sharon E.; Levitt, Pat; Nelson, Charles A., III.

    2010-01-01

    Early life events can exert a powerful influence on both the pattern of brain architecture and behavioral development. In this study a conceptual framework is provided for considering how the structure of early experience gets "under the skin." The study begins with a description of the genetic framework that lays the foundation for brain…

  4. Public School Teachers' Knowledge, Perception, and Implementation of Brain-Based Learning Practices

    Science.gov (United States)

    Wachob, David A.

    2012-01-01

    The purpose of this study was to determine K-12 teachers' knowledge, beliefs, and practices of brain-based learning strategies in western Pennsylvania schools. The following five research questions were explored: (a) What is the extent of knowledge K-12 public school teachers have about the indicators of brain-based learning and Brain Gym?;…

  5. Operator support architecture for monitoring abnormal symptoms of nuclear power plant based on knowledge engineering

    International Nuclear Information System (INIS)

    An architecture to support nuclear power plant operators for monitoring abnormal symptoms has been proposed based on the techniques of knowledge engineering, and the feasibility of a plant monitoring support system was investigated. The purpose of the support system is to present the operators with useful information so that they can make correct judgment at an early and subtle stage of abnormal plant conditions. In the architecture proposed, abductive reasoning is performed to search for causal events and deductive one to predict consequential events using the knowledge representing plant components as frames and those representing causal relations as production rules. A method to deal with uncertainties in each types of reasoning has been adopted, and it is used to rank several hypotheses of causal events and to assess the importance of plant parameters for monitoring. A prototype system was developed, and its usefulness was tested using a case of failure in a recirculation pump of a BWR plant. (author)

  6. Non-stationarity in the "resting brain's" modular architecture.

    Directory of Open Access Journals (Sweden)

    David T Jones

    Full Text Available Task-free functional magnetic resonance imaging (TF-fMRI has great potential for advancing the understanding and treatment of neurologic illness. However, as with all measures of neural activity, variability is a hallmark of intrinsic connectivity networks (ICNs identified by TF-fMRI. This variability has hampered efforts to define a robust metric of connectivity suitable as a biomarker for neurologic illness. We hypothesized that some of this variability rather than representing noise in the measurement process, is related to a fundamental feature of connectivity within ICNs, which is their non-stationary nature. To test this hypothesis, we used a large (n = 892 population-based sample of older subjects to construct a well characterized atlas of 68 functional regions, which were categorized based on independent component analysis network of origin, anatomical locations, and a functional meta-analysis. These regions were then used to construct dynamic graphical representations of brain connectivity within a sliding time window for each subject. This allowed us to demonstrate the non-stationary nature of the brain's modular organization and assign each region to a "meta-modular" group. Using this grouping, we then compared dwell time in strong sub-network configurations of the default mode network (DMN between 28 subjects with Alzheimer's dementia and 56 cognitively normal elderly subjects matched 1:2 on age, gender, and education. We found that differences in connectivity we and others have previously observed in Alzheimer's disease can be explained by differences in dwell time in DMN sub-network configurations, rather than steady state connectivity magnitude. DMN dwell time in specific modular configurations may also underlie the TF-fMRI findings that have been described in mild cognitive impairment and cognitively normal subjects who are at risk for Alzheimer's dementia.

  7. Architectural Knowledge: key flows and processes in designing an inter-organizational technological platform

    OpenAIRE

    Amel Attour; Maelle Della-Peruta

    2014-01-01

    The main objective is to identify which knowledge flows are key elements for designing an inter-organisational technological platform. It mobilizes two theories: the literature of platform strategies and the architectural innovation theory. In the literature, the technological platform is already existing, is the property of only one firm and it is the starting point for an inter-organisational innovation process because it is enhanced and enriched by niche players. This paper considers the c...

  8. E-learning networked environments and architectures a knowledge processing perspective

    CERN Document Server

    Wu, Xindong; Pierre, Samuel

    2010-01-01

    This book provides state-of-the-art e-learning networked environments and architectures carried out over the last few years from a knowledge management perspective. It contains a comprehensive discussion of e-learning concepts, models, experiments and best practices. Presenting a wide-ranging survey of methods and applications from contributors from around the world, this book will be a valuable resource for researchers, practitioners and graduates.

  9. The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture.

    Science.gov (United States)

    Fan, Lingzhong; Li, Hai; Zhuo, Junjie; Zhang, Yu; Wang, Jiaojian; Chen, Liangfu; Yang, Zhengyi; Chu, Congying; Xie, Sangma; Laird, Angela R; Fox, Peter T; Eickhoff, Simon B; Yu, Chunshui; Jiang, Tianzi

    2016-08-01

    The human brain atlases that allow correlating brain anatomy with psychological and cognitive functions are in transition from ex vivo histology-based printed atlases to digital brain maps providing multimodal in vivo information. Many current human brain atlases cover only specific structures, lack fine-grained parcellations, and fail to provide functionally important connectivity information. Using noninvasive multimodal neuroimaging techniques, we designed a connectivity-based parcellation framework that identifies the subdivisions of the entire human brain, revealing the in vivo connectivity architecture. The resulting human Brainnetome Atlas, with 210 cortical and 36 subcortical subregions, provides a fine-grained, cross-validated atlas and contains information on both anatomical and functional connections. Additionally, we further mapped the delineated structures to mental processes by reference to the BrainMap database. It thus provides an objective and stable starting point from which to explore the complex relationships between structure, connectivity, and function, and eventually improves understanding of how the human brain works. The human Brainnetome Atlas will be made freely available for download at http://atlas.brainnetome.org, so that whole brain parcellations, connections, and functional data will be readily available for researchers to use in their investigations into healthy and pathological states. PMID:27230218

  10. Tai Chi Chuan Optimizes the Functional Organization of the Intrinsic Human Brain Architecture in Older Adults

    OpenAIRE

    Jing Luo; Xi-Nian Zuo

    2014-01-01

    Whether Tai Chi Chuan (TCC) can influence the intrinsic functional architecture of the human brain remains unclear. To examine TCC-associated changes in functional connectomes, resting-state functional magnetic resonance images were acquired from 40 older individuals including 22 experienced TCC practitioners (experts) and 18 demographically matched TCC-naïve healthy controls, and their local functional homogeneities across the cortical mantle were compared. Compared to the controls, the TCC ...

  11. Tai Chi Chuan optimizes the functional organization of the intrinsic human brain architecture in older adults

    OpenAIRE

    Wei, Gao-Xia; Dong, Hao-Ming; Yang, Zhi; Luo, Jing; Zuo, Xi-Nian

    2014-01-01

    Whether Tai Chi Chuan (TCC) can influence the intrinsic functional architecture of the human brain remains unclear. To examine TCC-associated changes in functional connectomes, resting-state functional magnetic resonance images were acquired from 40 older individuals including 22 experienced TCC practitioners (experts) and 18 demographically matched TCC-naïve healthy controls, and their local functional homogeneities across the cortical mantle were compared. Compared to the controls, the TCC ...

  12. A Development Architecture for Serious Games Using BCI (Brain Computer Interface) Sensors

    OpenAIRE

    Kyhyun Um; Yunsick Sung; Kyungeun Cho

    2012-01-01

    Games that use brainwaves via brain–computer interface (BCI) devices, to improve brain functions are known as BCI serious games. Due to the difficulty of developing BCI serious games, various BCI engines and authoring tools are required, and these reduce the development time and cost. However, it is desirable to reduce the amount of technical knowledge of brain functions and BCI devices needed by game developers. Moreover, a systematic BCI serious game development process is required. In this...

  13. Preservation vs Innovation. Sustainable rehabilitation in architectural preservation contexts: knowledge, techniques, languages

    Directory of Open Access Journals (Sweden)

    Riccardo Gulli

    2012-12-01

    Full Text Available The theme of the preservation of the characteristics of protected architectural heritage must nowadays be correlated to new requirements for the adaptation of existing buildings to performance standards. This subject raises new questions about the theoretical assumptions and tools to be adopted to coherently answer that request. Focusing on the theme of energy requalification of heritage buildings - the primary focus of interest for the reduction of pollution emissions, according to Horizon 2020 objectives - the preservation of the meanings of an architecture work and of its linguistic, typological and material characteristics proofs to be essential for protection interventions on buildings. However this can’t be considered exhaustive, as the raised issue necessarily requires to be further addressed within the speculative domain of Technique, or rather to open out to the contribution that innovation processes and methods belonging to the field of scientific knowledge could offer.

  14. Connecting Learning: Brain-Based Strategies for Linking Prior Knowledge in the Library Media Center

    Science.gov (United States)

    Vanderbilt, Kathi L.

    2005-01-01

    The brain is a complex organ and learning is a complex process. While there is not complete agreement among researchers about brain-based learning and its direct connection to neuroscience, knowledge about the brain as well as the examination of cognitive psychology, anthropology, professional experience, and educational research can provide…

  15. Disrutpted resting-state functional architecture of the brain after 45-day simulated microgravity

    Directory of Open Access Journals (Sweden)

    Yuan eZhou

    2014-06-01

    Full Text Available Long-term spaceflight induces both physiological and psychological changes in astronauts. To understand the neural mechanisms underlying these physiological and psychological changes, it is critical to investigate the effects of microgravity on the functional architecture of the brain. In this study, we used resting-state functional MRI (rs-fMRI to study whether the functional architecture of the brain is altered after 45 days of -6° head-down tilt (HDT bed rest, which is a reliable model for the simulation of microgravity. Sixteen healthy male volunteers underwent rs-fMRI scans before and after 45 days of -6° HDT bed rest. Specifically, we used a commonly employed graph-based measure of network organization, i.e., degree centrality (DC, to perform a full-brain exploration of the regions that were influenced by simulated microgravity. We subsequently examined the functional connectivities of these regions using a seed-based resting-state functional connectivity (RSFC analysis. We found decreased DC in two regions, the left anterior insula (aINS and the anterior part of the middle cingulate cortex (MCC; also called the dorsal anterior cingulate cortex in many studies, in the male volunteers after 45 days of -6° HDT bed rest. Furthermore, seed-based RSFC analyses revealed that a functional network anchored in the aINS and MCC was particularly influenced by simulated microgravity. These results provide evidence that simulated microgravity alters the resting-state functional architecture of the brains of males and suggest that the processing of salience information, which is primarily subserved by the aINS–MCC functional network, is particularly influenced by spaceflight. The current findings provide a new perspective for understanding the relationships between microgravity, cognitive function, autonomic neural function and central neural activity.

  16. Building the Knowledge Base to Support the Automatic Animation Generation of Chinese Traditional Architecture

    Science.gov (United States)

    Wei, Gongjin; Bai, Weijing; Yin, Meifang; Zhang, Songmao

    We present a practice of applying the Semantic Web technologies in the domain of Chinese traditional architecture. A knowledge base consisting of one ontology and four rule bases is built to support the automatic generation of animations that demonstrate the construction of various Chinese timber structures based on the user's input. Different Semantic Web formalisms are used, e.g., OWL DL, SWRL and Jess, to capture the domain knowledge, including the wooden components needed for a given building, construction sequence, and the 3D size and position of every piece of wood. Our experience in exploiting the current Semantic Web technologies in real-world application systems indicates their prominent advantages (such as the reasoning facilities and modeling tools) as well as the limitations (such as low efficiency).

  17. An architecture for integrating distributed and cooperating knowledge-based Air Force decision aids

    Science.gov (United States)

    Nugent, Richard O.; Tucker, Richard W.

    1988-01-01

    MITRE has been developing a Knowledge-Based Battle Management Testbed for evaluating the viability of integrating independently-developed knowledge-based decision aids in the Air Force tactical domain. The primary goal for the testbed architecture is to permit a new system to be added to a testbed with little change to the system's software. Each system that connects to the testbed network declares that it can provide a number of services to other systems. When a system wants to use another system's service, it does not address the server system by name, but instead transmits a request to the testbed network asking for a particular service to be performed. A key component of the testbed architecture is a common database which uses a relational database management system (RDBMS). The RDBMS provides a database update notification service to requesting systems. Normally, each system is expected to monitor data relations of interest to it. Alternatively, a system may broadcast an announcement message to inform other systems that an event of potential interest has occurred. Current research is aimed at dealing with issues resulting from integration efforts, such as dealing with potential mismatches of each system's assumptions about the common database, decentralizing network control, and coordinating multiple agents.

  18. Aberrant Functional Whole-Brain Network Architecture in Patients With Schizophrenia: A Meta-analysis.

    Science.gov (United States)

    Kambeitz, Joseph; Kambeitz-Ilankovic, Lana; Cabral, Carlos; Dwyer, Dominic B; Calhoun, Vince D; van den Heuvel, Martijn P; Falkai, Peter; Koutsouleris, Nikolaos; Malchow, Berend

    2016-07-01

    Findings from multiple lines of research provide evidence of aberrant functional brain connectivity in schizophrenia. By using graph-analytical measures, recent studies indicate that patients with schizophrenia exhibit changes in the organizational principles of whole-brain networks and that these changes relate to cognitive symptoms. However, there has not been a systematic investigation of functional brain network changes in schizophrenia to test the consistency of these changes across multiple studies. A comprehensive literature search was conducted to identify all available functional graph-analytical studies in patients with schizophrenia. Effect size measures were derived from each study and entered in a random-effects meta-analytical model. All models were tested for effects of potential moderator variables as well as for the presence of publication bias. The results of a total of n = 13 functional neuroimaging studies indicated that brain networks in patients with schizophrenia exhibit significant decreases in measures of local organization (g = -0.56, P = .02) and significant decreases in small-worldness (g = -0.65, P = .01) whereas global short communication paths seemed to be preserved (g = 0.26, P = .32). There was no evidence for a publication bias or moderator effects. The present meta- analysis demonstrates significant changes in whole brain network architecture associated with schizophrenia across studies. PMID:27460615

  19. Knowledge Management Practice in Two Australian Architecture-Engineering-Construction (AEC Companies

    Directory of Open Access Journals (Sweden)

    Patrick Zou

    2012-11-01

    Full Text Available Knowledge management (KM could be described as a management system that supports the creation, sharing and retrieving of valued information, expertise and insight within and across communities of people and related organizations using information and communication technologies and hence it is a combination of the effective application of information technlogy and management of human resources. KM is becoming a core competitive factor in construction operations. This paper presents the results of two case studies of KM practices in large AEC (architecture, engineering and construction companies through desk-top study and semi-structured interviews. The results indicate that implementing KM in AEC companies leads to competitive advantages and improved decision-making, problem solving and business performance. The results also indicateed that while technology plays an important role, top management commitment, total employee involvement, performance assessment and the culture of knowledge-learning and sharing must be considered when implementing KM. Therefore it is suggested that the implementation of KM should incorporate the company's vision, work processes, technology and culture, to improve the ability of knowledge creating, capturing, sharing, retrieving and ultimately, to improve the company's competitive advantage, decision making, problem solving and innovation.

  20. Knowledge base and sensor bus messaging service architecture for critical tsunami warning and decision-support

    Science.gov (United States)

    Sabeur, Z. A.; Wächter, J.; Middleton, S. E.; Zlatev, Z.; Häner, R.; Hammitzsch, M.; Loewe, P.

    2012-04-01

    The intelligent management of large volumes of environmental monitoring data for early tsunami warning requires the deployment of robust and scalable service oriented infrastructure that is supported by an agile knowledge-base for critical decision-support In the TRIDEC project (TRIDEC 2010-2013), a sensor observation service bus of the TRIDEC system is being developed for the advancement of complex tsunami event processing and management. Further, a dedicated TRIDEC system knowledge-base is being implemented to enable on-demand access to semantically rich OGC SWE compliant hydrodynamic observations and operationally oriented meta-information to multiple subscribers. TRIDEC decision support requires a scalable and agile real-time processing architecture which enables fast response to evolving subscribers requirements as the tsunami crisis develops. This is also achieved with the support of intelligent processing services which specialise in multi-level fusion methods with relevance feedback and deep learning. The TRIDEC knowledge base development work coupled with that of the generic sensor bus platform shall be presented to demonstrate advanced decision-support with situation awareness in context of tsunami early warning and crisis management.

  1. A multi-agent architecture for sharing knowledge and experimental data about waste water treatment plants through the Internet

    International Nuclear Information System (INIS)

    In this paper, we present a first prototype of a local multi-agent architecture for the sharing of knowledge and experimental data about waste water treatment plants through the Internet, or more specifically the WWW. Applying a net browser such as nets cape, a user can have access to a CLIPS expert system (advising on waste water cleaning technologies) and experimental data files. The discussed local prototype is part of proposed global agent architecture. (authors)

  2. MR Image Segmentation of Patients’ Brain Using Disease Specific a Priori Knowledge

    Directory of Open Access Journals (Sweden)

    Hassan Tavakkoli & Ali Sadeqi

    2012-02-01

    Full Text Available Segmentation of high quality brain MR images using a priori knowledge about brain structuresenables a more accurate and comprehensive interpretation. Benefits of applying a prioriknowledge about the brain structures may also be employed for image segmentation of specificbrain and neural patients. Such procedure may be performed to determine the disease stage ormonitor its gradual progression over time. However segmenting brain images of patients usinggeneral a priori knowledge which corresponds to healthy subjects would result in inaccurate andunreliable interpretation in the regions which are affected by the disease. In this paper, atechnique is proposed for extracting a priori knowledge about structural distribution of differentbrain tissues affected by a specific disease to be applied for accurate segmentation of thepatients’ brain images. For this purpose, extracted a priori knowledge is gradually represented asdisease specific probability maps throughout an iterative process, and then is utilized in astatistical approach for segmentation of new patients’ images. Experiments conducted on a largeset of images acquired from patients with a similar neurodegenerative disease implied success ofthe proposed technique for representing meaningful a priori knowledge as disease specificprobability maps. Promising results obtained also indicated an accurate segmentation of brainMR images of the new patients using the represented a priori knowledge, into three tissueclasses of gray matter, white matter, and cerebrospinal fluid. This enables an accurate estimationof tissues’ thickness and volumes and can be counted as a substantial forward step for morereliable monitoring and interpretation of progression in specific brain and neural diseases.

  3. An Actor-Critic architecture and simulator for goal-directed Brain-Machine Interfaces.

    Science.gov (United States)

    Mahmoudi, Babak; Principe, Jose C; Sanchez, Justin C

    2009-01-01

    The Perception-Action Cycle (PAC) is a central component of goal-directed behavior because it links internal percepts with external outcomes in the environment. Using inspiration from the PAC, we are developing a Brain-Machine Interface control architecture that utilizes both motor commands and goal information directly from the brain to navigate to novel targets in an environment. An Actor-Critic algorithm was selected for decoding the neural motor commands because it is a PAC-based computational framework where the perception component is implemented in the critic structure and the actor is responsible for taking actions. We develop in this work a biologically realistic simulator to analyze the performance of the decoder in terms of convergence and target acquisition. Experience from the simulator will guide parameter selection and assist in understanding the architecture before animal experiments. By varying the signal to noise ratio of the neural input and error signal, we were able to demonstrate how the learning rate and initial conditions affect a motor control target selection task. In this framework, the naïve decoder was able to reach targets in the presence of noise in the error signal and neural motor command with 98% accuracy. PMID:19963795

  4. Integration of Structural Knowledge in Design Studio Project: Assessment Study of Curriculum In Architecture Course in University Of Malaya

    Directory of Open Access Journals (Sweden)

    Aniza Abdul Aziz

    2010-12-01

    Full Text Available Architectural education should advance in parallel with the industrial growth of building technology. Universities as producers of future architects have yet to develop curriculums for building technology to suit the growth of the building industry. This gap between education and industrial growth has been a topic of debate for many researchers who are concerned about architectural pedagogy. Architectural instruction further aggravated the problem whereby in most architectural schools worldwide, teaching is divided between the design studio, where the design projects are taught and lecture classes where the technical parts are taught. The latter should be integrated with design studio to enhance design levels. Students face difficulty integrating and applying the structural knowledge gained from structure classes into their design. One explanation for this deficiency is because the current architectural structure subject's content is borrowed from an engineering syllabus. This study will examine the course content, instruction styles and method of teaching structure subjects and will investigate the learning outcomes of design studio through students' performance and perception in integrating structural knowledge in their design projects. Respondents were students from Year 1 to Year 5 doing their Bachelor of Science in Architecture and Bachelor of Architecture degrees in University of Malaya. Semi-structured interviews were conducted with the design studio coordinators and structure lecturers. This study aims to find the ideal course content/method of teaching to facilitate more integration between structure and design studio.

  5. RoboBrain: Large-Scale Knowledge Engine for Robots

    OpenAIRE

    Saxena, Ashutosh; Jain, Ashesh; Sener, Ozan; Jami, Aditya; Misra, Dipendra K.; Koppula, Hema S.

    2014-01-01

    In this paper we introduce a knowledge engine, which learns and shares knowledge representations, for robots to carry out a variety of tasks. Building such an engine brings with it the challenge of dealing with multiple data modalities including symbols, natural language, haptic senses, robot trajectories, visual features and many others. The \\textit{knowledge} stored in the engine comes from multiple sources including physical interactions that robots have while performing tasks (perception,...

  6. How to avoid brain drain? Knowledge management as a competitive advantage. Case: Finnish SME growth companies

    OpenAIRE

    Ahlbäck, Markus

    2015-01-01

    INTRODUCTION: The objective of this study is to examine ways of controlling brain drain in growth SMEs and finding competitive edge from knowledge management. The study starts with a pre-examination of growth factors that would explain company growth. As literature and a preliminary research that was conducted go to show it is difficult to find factors which unambiguously would explain a firm's growth. Thus, knowledge management and brain drain were chosen to be looked into more deepl...

  7. Patterns of regional brain hypometabolism associated with knowledge of semantic features and categories in alzheimer's disease

    DEFF Research Database (Denmark)

    Zahn, R.; Garrard, P.; Talazko, J.;

    2006-01-01

    The study of semantic memory in patients with Alzheimer's disease (AD) has raised important questions about the representation of conceptual knowledge in the human brain. It is still unknown whether semantic memory impairments are caused by localized damage to specialized regions or by diffuse...... and nonliving concepts, as well as visual feature knowledge of living objects, and against distributed accounts of semantic memory that view visual and functional features of living and nonliving objects as distributed across a common set of brain areas....

  8. Architecture and Knowledge-Driven Self-Adaptive Security in Smart Space

    Directory of Open Access Journals (Sweden)

    Antti Evesti

    2013-03-01

    Full Text Available Dynamic and heterogeneous smart spaces cause challenges for security because it is impossible to anticipate all the possible changes at design-time. Self-adaptive security is an applicable solution for this challenge. This paper presents an architectural approach for security adaptation in smart spaces. The approach combines an adaptation loop, Information Security Measuring Ontology (ISMO and a smart space security-control model. The adaptation loop includes phases to monitor, analyze, plan and execute changes in the smart space. The ISMO offers input knowledge for the adaptation loop and the security-control model enforces dynamic access control policies. The approach is novel because it defines the whole adaptation loop and knowledge required in each phase of the adaptation. The contributions are validated as a part of the smart space pilot implementation. The approach offers reusable and extensible means to achieve adaptive security in smart spaces and up-to-date access control for devices that appear in the space. Hence, the approach supports the work of smart space application developers.

  9. Macroscopic brain architecture changes and white matter pathology in acromegaly: a clinicoradiological study.

    Science.gov (United States)

    Sievers, C; Sämann, P G; Dose, T; Dimopoulou, C; Spieler, D; Roemmler, J; Schopohl, J; Mueller, M; Schneider, H J; Czisch, M; Pfister, H; Stalla, G K

    2009-01-01

    Although long-term exposure of the brain to increased GH/IGF-1 likely influences cerebral functions, no in vivo studies have been directed towards changes of the brain structure in acromegaly. Here, we used high resolution magnetic resonance images to compare volumes of gray matter (GM), white matter (WM) and cerebrospinal fluid (CSF) of forty-four patients with acromegaly to an age and gender matched, healthy control group (n = 44). In addition, white matter lesions (WMLs) were quantified and graded. Patients exhibited larger GM (+3.7% compared with controls, P = 0.018) and WM volumes (+5.1%, P = 0.035) at the expense of CSF. Differences of WML counts between patients and controls were subtle, however, showing more patients in the 21-40 lesions category (P = 0.044). In conclusion, this MRI study provides first evidence that acromegalic patients exhibit disturbances of the macroscopic brain tissue architecture. Furthermore, acromegalic patients may have an increased risk of neurovascular pathology, likely due to secondary metabolic and vascular comorbidities. PMID:18836838

  10. Reconfiguration of brain network architecture to support executive control in aging.

    Science.gov (United States)

    Gallen, Courtney L; Turner, Gary R; Adnan, Areeba; D'Esposito, Mark

    2016-08-01

    Aging is accompanied by declines in executive control abilities and changes in underlying brain network architecture. Here, we examined brain networks in young and older adults during a task-free resting state and an N-back task and investigated age-related changes in the modular network organization of the brain. Compared with young adults, older adults showed larger changes in network organization between resting state and task. Although young adults exhibited increased connectivity between lateral frontal regions and other network modules during the most difficult task condition, older adults also exhibited this pattern of increased connectivity during less-demanding task conditions. Moreover, the increase in between-module connectivity in older adults was related to faster task performance and greater fractional anisotropy of the superior longitudinal fasciculus. These results demonstrate that older adults who exhibit more pronounced network changes between a resting state and task have better executive control performance and greater structural connectivity of a core frontal-posterior white matter pathway. PMID:27318132

  11. "Do octopuses have a brain?" Knowledge, perceptions and attitudes towards neuroscience at school.

    Science.gov (United States)

    Sperduti, Alessandra; Crivellaro, Federica; Rossi, Paola Francesca; Bondioli, Luca

    2012-01-01

    The present study contributes to the question of school literacy about the brain, with an original survey conducted on Italian students from the 3(rd) to 10(th) grades (n=508). The main goal was to test student's knowledge, attitudes, and interests about neuroscience, to assess needs, prospects, and difficulties in teaching about the brain from elementary to high school. A written questionnaire, maintaining anonymity, asked 12 close-ended multiple choice questions on topics related to human and animal brains, plus one facultative open-ended question about interests and curiosities on brain topics. The results show that respondents have a fragmentary level of basic knowledge about the brain, with aspects related to brain functions and consciousness the most challenging. As expected, degrees of performance improve with school level; elementary school students answered correctly an average number of 5.3 questions, middle school 6.5, and high school 7.4. Overall, students show great interest in the brain, as shown by the large number of questions gathered through the open-ended question (n=384). Other topics are addressed, mostly related to brain structure/functions and the role of the brain in the everyday life. The survey indicates the need of more thorough school programs on this subject, reinforced by interdisciplinary teaching where comparative anatomy and evolutionary aspects of brain development are covered. PMID:23082231

  12. "Do octopuses have a brain?" Knowledge, perceptions and attitudes towards neuroscience at school.

    Directory of Open Access Journals (Sweden)

    Alessandra Sperduti

    Full Text Available The present study contributes to the question of school literacy about the brain, with an original survey conducted on Italian students from the 3(rd to 10(th grades (n=508. The main goal was to test student's knowledge, attitudes, and interests about neuroscience, to assess needs, prospects, and difficulties in teaching about the brain from elementary to high school. A written questionnaire, maintaining anonymity, asked 12 close-ended multiple choice questions on topics related to human and animal brains, plus one facultative open-ended question about interests and curiosities on brain topics. The results show that respondents have a fragmentary level of basic knowledge about the brain, with aspects related to brain functions and consciousness the most challenging. As expected, degrees of performance improve with school level; elementary school students answered correctly an average number of 5.3 questions, middle school 6.5, and high school 7.4. Overall, students show great interest in the brain, as shown by the large number of questions gathered through the open-ended question (n=384. Other topics are addressed, mostly related to brain structure/functions and the role of the brain in the everyday life. The survey indicates the need of more thorough school programs on this subject, reinforced by interdisciplinary teaching where comparative anatomy and evolutionary aspects of brain development are covered.

  13. Traumatic Brain Injury: Persistent Misconceptions and Knowledge Gaps among Educators

    Science.gov (United States)

    Ettel, Deborah; Glang, Ann E.; Todis, Bonnie; Davies, Susan C.

    2016-01-01

    Each year approximately 700,000 U.S. children aged 0-19 years sustain a traumatic brain injury (TBI) placing them at risk for academic, cognitive, and behavioural challenges. Although TBI has been a special education disability category for 25 years, prevalence studies show that of the 145,000 students each year who sustain long-term injury from…

  14. Spatial and Functional Architecture of the Mammalian Brain Stem Respiratory Network: A Hierarchy of Three Oscillatory Mechanisms

    OpenAIRE

    Smith, J C; Abdala, A. P. L.; Koizumi, H.; Rybak, I. A.; Paton, J. F. R.

    2007-01-01

    Mammalian central pattern generators (CPGs) producing rhythmic movements exhibit extremely robust and flexible behavior. Network architectures that enable these features are not well understood. Here we studied organization of the brain stem respiratory CPG. By sequential rostral to caudal transections through the pontine-medullary respiratory network within an in situ perfused rat brain stem–spinal cord preparation, we showed that network dynamics reorganized and new rhythmogenic mechanisms ...

  15. Implementation of a metadata architecture and knowledge collection to support semantic interoperability in an enterprise data warehouse.

    Science.gov (United States)

    Dhaval, Rakesh; Borlawsky, Tara; Ostrander, Michael; Santangelo, Jennifer; Kamal, Jyoti; Payne, Philip R O

    2008-01-01

    In order to enhance interoperability between enterprise systems, and improve data validity and reliability throughout The Ohio State University Medical Center (OSUMC), we have initiated the development of an ontology-anchored metadata architecture and knowledge collection for our enterprise data warehouse. The metadata and corresponding semantic relationships stored in the OSUMC knowledge collection are intended to promote consistency and interoperability across the heterogeneous clinical, research, business and education information managed within the data warehouse. PMID:18999040

  16. The Perceptions of Teachers Regarding Their Knowledge, Beliefs, and Practices of Brain-Based Learning Strategies

    Science.gov (United States)

    Ridley, Janice Rebecca Becky

    2012-01-01

    The purpose of this dissertation was to assess K-12 teachers' perceptions of knowledge, beliefs, and practices toward brain-based learning strategies, how their knowledge relates to their beliefs and practices, and how their beliefs relate to their classroom practices. This research also investigated relationships between teachers'…

  17. Transcriptional profiles of supragranular-enriched genes associate with corticocortical network architecture in the human brain.

    Science.gov (United States)

    Krienen, Fenna M; Yeo, B T Thomas; Ge, Tian; Buckner, Randy L; Sherwood, Chet C

    2016-01-26

    The human brain is patterned with disproportionately large, distributed cerebral networks that connect multiple association zones in the frontal, temporal, and parietal lobes. The expansion of the cortical surface, along with the emergence of long-range connectivity networks, may be reflected in changes to the underlying molecular architecture. Using the Allen Institute's human brain transcriptional atlas, we demonstrate that genes particularly enriched in supragranular layers of the human cerebral cortex relative to mouse distinguish major cortical classes. The topography of transcriptional expression reflects large-scale brain network organization consistent with estimates from functional connectivity MRI and anatomical tracing in nonhuman primates. Microarray expression data for genes preferentially expressed in human upper layers (II/III), but enriched only in lower layers (V/VI) of mouse, were cross-correlated to identify molecular profiles across the cerebral cortex of postmortem human brains (n = 6). Unimodal sensory and motor zones have similar molecular profiles, despite being distributed across the cortical mantle. Sensory/motor profiles were anticorrelated with paralimbic and certain distributed association network profiles. Tests of alternative gene sets did not consistently distinguish sensory and motor regions from paralimbic and association regions: (i) genes enriched in supragranular layers in both humans and mice, (ii) genes cortically enriched in humans relative to nonhuman primates, (iii) genes related to connectivity in rodents, (iv) genes associated with human and mouse connectivity, and (v) 1,454 gene sets curated from known gene ontologies. Molecular innovations of upper cortical layers may be an important component in the evolution of long-range corticocortical projections. PMID:26739559

  18. Tai Chi Chuan Optimizes the Functional Organization of the Intrinsic Human Brain Architecture in Older Adults

    Directory of Open Access Journals (Sweden)

    Gao-Xia eWei

    2014-04-01

    Full Text Available Whether Tai Chi Chuan (TCC can influence the intrinsic functional architecture of the human brain remains unclear. To examine TCC-associated changes in functional connectomes, resting-state functional magnetic resonance images were acquired from 40 older individuals including 22 experienced TCC practitioners (experts and 18 demographically matched TCC-naïve healthy controls, and their local functional homogeneities across the cortical mantle were compared. Compared to the controls, the TCC experts had significantly greater and more experience-dependent functional homogeneity in the right postcentral gyrus (PosCG and less functional homogeneity in the left anterior cingulate cortex (ACC and the right dorsal lateral prefrontal cortex (DLPFC. Increased functional homogeneity in the PosCG was correlated with TCC experience. Intriguingly, decreases in functional homogeneity (improved functional specialization in the left ACC and increases in functional homogeneity (improved functional integration in the right PosCG both predicted performance gains on attention network behavior tests. These findings provide evidence for the functional plasticity of the brain’s intrinsic architecture toward optimizing locally functional organization, with great implications for understanding the effects of TCC on cognition, behavior and health in aging population.

  19. Mind, Brain, and Literacy: Biomarkers as Usable Knowledge for Education

    Science.gov (United States)

    Goswami, Usha

    2009-01-01

    Neuroscience has the potential to make some very exciting contributions to education and pedagogy. However, it is important to ask whether the insights from neuroscience studies can provide "usable knowledge" for educators. With respect to literacy, for example, current neuroimaging methods allow us to ask research questions about how the brain…

  20. Harnessing the Risk-Related Data Supply Chain: An Information Architecture Approach to Enriching Human System Research and Operations Knowledge

    Science.gov (United States)

    Buquo, Lynn E.; Johnson-Throop, Kathy A.

    2011-01-01

    An Information Architecture facilitates the understanding and, hence, harnessing of the human system risk-related data supply chain which enhances the ability to securely collect, integrate, and share data assets that improve human system research and operations. By mapping the risk-related data flow from raw data to useable information and knowledge (think of it as a data supply chain), the Human Research Program (HRP) and Space Life Science Directorate (SLSD) are building an information architecture plan to leverage their existing, and often shared, IT infrastructure.

  1. A framework for acquisition and application of software architecture evolution knowledge

    OpenAIRE

    Ahmad, Aakash; Jamshidi, Pooyan; Pahl, Claus

    2013-01-01

    Software systems continuously evolve as a consequence of frequent changes in their functional requirements and the environment surrounding them. Architecture-centric software evolution (ACSE) enables changes in software structure and behaviour while abstracting the complex implementation-specific details. However, due to recurring evolution there is a need for solutions that enable a systematic reuse of frequent changes in software architectures. In recent years, architecture change patterns ...

  2. Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation

    Directory of Open Access Journals (Sweden)

    Luissint Anny-Claude

    2012-11-01

    Full Text Available Abstract The Blood–brain barrier (BBB, present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and proper neuronal function. The barrier properties of these specialized endothelial cells notably depend on tight junctions (TJs between adjacent cells: TJs are dynamic structures consisting of a number of transmembrane and membrane-associated cytoplasmic proteins, which are assembled in a multimolecular complex and acting as a platform for intracellular signaling. Although the structural composition of these complexes has been well described in the recent years, our knowledge about their functional regulation still remains fragmentary. Importantly, pericytes, embedded in the vascular basement membrane, and perivascular microglial cells, astrocytes and neurons contribute to the regulation of endothelial TJs and BBB function, altogether constituting the so-called neurovascular unit. The present review summarizes our current understanding of the structure and functional regulation of endothelial TJs at the BBB. Accumulating evidence points to a correlation between BBB dysfunction, alteration of TJ complexes and progression of a variety of CNS diseases, such as stroke, multiple sclerosis and brain tumors, as well as neurodegenerative diseases like Parkinson’s and Alzheimer’s diseases. Understanding how TJ integrity is controlled may thus help improve drug delivery across the BBB and the design of therapeutic strategies for neurological disorders.

  3. A hybrid system using symbolic and numeric knowledge for the semantic annotation of sulco-gyral anatomy in brain MRI images.

    Science.gov (United States)

    Mechouche, Ammar; Morandi, Xavier; Golbreich, Christine; Gibaud, Bernard

    2009-08-01

    This paper describes an interactive system for the semantic annotation of brain magnetic resonance images. The system uses both a numerical atlas and symbolic knowledge of brain anatomical structures depicted using the Semantic Web standards. This knowledge is combined with graphical data, automatically extracted from the images by imaging tools. The annotations of parts of gyri and sulci, in a region of interest, rely on constraint satisfaction problem solving and description logics inferences. The system is run on a client-server architecture, using Web services and including a sophisticated visualization tool. An evaluation of the system was done using normal (healthy) and pathological cases. The results obtained so far demonstrate that the system produces annotations with high precision and quality. PMID:19622437

  4. Architecture on Architecture

    DEFF Research Database (Denmark)

    Olesen, Karen

    2016-01-01

    This paper will discuss the challenges faced by architectural education today. It takes as its starting point the double commitment of any school of architecture: on the one hand the task of preserving the particular knowledge that belongs to the discipline of architecture, and on the other hand...... the obligation to prepare students to perform in a profession that is largely defined by forces outside that discipline. It will be proposed that the autonomy of architecture can be understood as a unique kind of information: as architecture’s self-reliance or knowledge-about itself. A knowledge that...... is not scientific or academic but is more like a latent body of data that we find embedded in existing works of architecture. This information, it is argued, is not limited by the historical context of the work. It can be thought of as a virtual capacity – a reservoir of spatial configurations that...

  5. An Architecture for Performance Optimization in a Collaborative Knowledge-Based Approach for  Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Juan Ramon Velasco

    2011-09-01

    Full Text Available Over the past few years, Intelligent Spaces (ISs have received the attention of many Wireless Sensor Network researchers. Recently, several studies have been devoted to identify their common capacities and to set up ISs over these networks. However, little attention has been paid to integrating Fuzzy Rule-Based Systems into collaborative Wireless Sensor Networks for the purpose of implementing ISs. This work presents a distributed architecture proposal for collaborative Fuzzy Rule-Based Systems embedded in Wireless Sensor Networks, which has been designed to optimize the implementation of ISs. This architecture includes the following: (a an optimized design for the inference engine; (b a visual interface; (c a module to reduce the redundancy and complexity of the knowledge bases; (d a module to evaluate the accuracy of the new knowledge base; (e a module to adapt the format of the rules to the structure used by the inference engine; and (f a communications protocol. As a real-world application of this architecture and the proposed methodologies, we show an application to the problem of modeling two plagues of the olive tree: prays (olive moth, Prays oleae Bern. and repilo (caused by the fungus Spilocaea oleagina. The results show that the architecture presented in this paper significantly decreases the consumption of resources (memory, CPU and battery without a substantial decrease in the accuracy of the inferred values.

  6. The HealthAgents ontology: knowledge representation in a distributed decision support system for brain tumours

    OpenAIRE

    Martínez Miranda, Juan Crisóforo; Sáez Silvestre, Carlos; Hu, B.; Croitoru, M; Roset, R; Dupplaw, D.; Lurgi, M.; Dasmahapatra, S.; Lewis, P

    2011-01-01

    In this paper we present our experience of representing the knowledge behind HealthAgents (HA), a distributed decision support system for brain tumour diagnosis. Our initial motivation came from the distributed nature of the information involved in the system and has been enriched by clinicians' requirements and data access restrictions. We present in detail the steps we have taken towards building our ontology starting from knowledge acquisition to data access and reasoning. We motivate our ...

  7. Brain-grounded theory of temporal and spatial design in architecture and the environment

    CERN Document Server

    Ando, Yoichi

    2016-01-01

    In this book, brain-grounded theory of temporal and spatial design in architecture and the environment is discussed. The author believes that it is a key to solving such global problems as environmental disorders and severe climate change as well as conflicts that are caused by the ill-conceived notion of “time is money”. There are three phases or aspects of a person’s life: the physical life, the spiritual or mental life, and the third stage of life, when a person moves from middle age into old age and can choose what he or she wishes to do instead of simply what must be done. This book describes the temporal design of the environment based on the theory of subjective preference, which could make it possible for an individual to realize a healthy life in all three phases. In his previously published work, the present author wrote that the theory of subjective preference has been established for the sound and visual fields based on neural evidence, and that subjective preference is an overall response o...

  8. Cis-regulatory architecture of a brain signaling center predates the origin of chordates.

    Science.gov (United States)

    Yao, Yao; Minor, Paul J; Zhao, Ying-Tao; Jeong, Yongsu; Pani, Ariel M; King, Anna N; Symmons, Orsolya; Gan, Lin; Cardoso, Wellington V; Spitz, François; Lowe, Christopher J; Epstein, Douglas J

    2016-05-01

    Genomic approaches have predicted hundreds of thousands of tissue-specific cis-regulatory sequences, but the determinants critical to their function and evolutionary history are mostly unknown. Here we systematically decode a set of brain enhancers active in the zona limitans intrathalamica (zli), a signaling center essential for vertebrate forebrain development via the secreted morphogen Sonic hedgehog (Shh). We apply a de novo motif analysis tool to identify six position-independent sequence motifs together with their cognate transcription factors that are essential for zli enhancer activity and Shh expression in the mouse embryo. Using knowledge of this regulatory lexicon, we discover new Shh zli enhancers in mice and a functionally equivalent element in hemichordates, indicating an ancient origin of the Shh zli regulatory network that predates the chordate phylum. These findings support a strategy for delineating functionally conserved enhancers in the absence of overt sequence homologies and over extensive evolutionary distances. PMID:27064252

  9. Virtual neurorobotics (VNR to accelerate development of plausible neuromorphic brain architectures

    Directory of Open Access Journals (Sweden)

    Philip H Goodman

    2007-11-01

    Full Text Available Traditional research in artificial intelligence and machine learning has viewed the brain as a specially adapted information-processing system. More recently the field of social robotics has been advanced to capture the important dynamics of human cognition and interaction. An overarching societal goal of this research is to incorporate the resultant knowledge about intelligence into technology for prosthetic, assistive, security, and decision support applications. However, despite many decades of investment in learning and classification systems, this paradigm has yet to yield truly “intelligent” systems. For this reason, many investigators are now attempting to incorporate more realistic neuromorphic properties into machine learning systems, encouraged by over two decades of neuroscience research that has provided parameters that characterize the brain’s interdependent genomic, proteomic, metabolomic, anatomic, and electrophysiological networks. Given the complexity of neural systems, developing tenable models to capture the essence of natural intelligence for real-time application requires that we discriminate features underlying information processing and intrinsic motivation from those reflecting biological constraints (such as maintaining structural integrity and transporting metabolic products. We propose herein a conceptual framework and an iterative method of virtual neurorobotics (VNR intended to rapidly forward-engineer and test progressively more complex putative neuromorphic brain prototypes for their ability to support intrinsically intelligent, intentional interaction with humans. The VNR system is based on the viewpoint that a truly intelligent system must be driven by emotion rather than programmed tasking, incorporating intrinsic motivation and intentionality. We report pilot results of a closed-loop, real-time interactive VNR system with a spiking neural brain, and provide a video demonstration as online supplemental

  10. Perceptions, Knowledge, Incentives, and Barriers of Brain Donation among African American Elders Enrolled in an Alzheimer's Research Program

    Science.gov (United States)

    Lambe, Susan; Cantwell, Nicole; Islam, Fareesa; Horvath, Kathy; Jefferson, Angela L.

    2011-01-01

    Purpose: To learn about African American older adults' knowledge and perceptions of brain donation, factors that relate to participating or not participating in a brain donation research program, and methods to increase African American brain donation commitment rates in the context of an Alzheimer's disease (AD) research program. Design and…

  11. A Knowledge Management Technology Architecture for Educational Research Organisations: Scaffolding Research Projects and Workflow Processing

    Science.gov (United States)

    Muthukumar; Hedberg, John G.

    2005-01-01

    There is growing recognition that the economic climate of the world is shifting towards a knowledge-based economy where knowledge will be cherished as the most prized asset. In this regard, technology can be leveraged as a useful tool in effectually managing the knowledge capital of an organisation. Although several research studies have advanced…

  12. Dialogic e-learning2learn: creating global digital networks and educational knowledge building architectures across diversity

    DEFF Research Database (Denmark)

    Sorensen, Elsebeth Korsgaard

    2007-01-01

    Abstract: Purpose – The purpose of this paper is to address the challenge and potential of online higher and continuing education, of fostering and promoting, in a global perspective across time and space, democratic values working for a better world. Design/methodology/approach – The paper...... presents a generalized dialogic learning architecture of networked collaborative learning and makes a plea for a theory-informed networked collaborative learning architecture and methodology appropriate for adult learners in higher and continuing education. Findings – Values include mutual political and...... intercultural understanding, collaboration, and tolerance to cultural and ethical diversity, and they are mediated through collaborative dialogue and knowledge-building processes between learners. While embedded, empirically, in a networked distance learning context, established through synchronous and...

  13. Classification and Comparison of Architecture Evolution Reuse Knowledge - A Systematic Review

    DEFF Research Database (Denmark)

    Ahmad, Aakash; Jamshidi, Pooyan; Pahl, Claus

    2014-01-01

    Context: Architecture-centric software evolution (ACSE) enables changes in system's structure and behaviour while maintaining a global view of the software to address evolution-centric trade-offs. The existing research and practices for ACSE primarily focus on design-time evolution and runtime...

  14. An architecture of knowledge management system based on agent and ontology

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    To solve the problems in knowledge management system (KMS), such as information sharing, the ability to extend and re-engineer, and the reusable ability of legacy systems in distributed and heterogeneous environments. This article presents a method based on agent and ontology of designing KMS. This method consists of two agencies. One is knowledge agency with three agents supporting knowledge management process. The other is application agency with three agents supporting knowledge application. In this method, ontology is used to represent the knowledge in knowledge base and the content in the message exchanged among agents. To demonstrate the advantages of this method, experiments have been carried out and the results imply that this method is efficient and effective for small and medium-size enterprises to design KMS.

  15. Architectural Reconstruction of 3D Building Objects through Semantic Knowledge Management

    OpenAIRE

    Yucong, Duan; Cruz, Christophe; Nicolle, Christophe

    2010-01-01

    International audience This paper presents an ongoing research which aims at combining geometrical analysis of point clouds and semantic rules to detect 3D building objects. Firstly by applying a previous semantic formalization investigation, we propose a classification of related knowledge as definition, partial knowledge and ambiguous knowledge to facilitate the understanding and design. Secondly an empirical implementation is conducted on a simplified building prototype complying with t...

  16. A Proposed Architecture for Implementing a Knowledge Management System in the Brazilian National Cancer Institute

    OpenAIRE

    José Geraldo Pereira Barbosa; Antônio Augusto Gonçalves; Vera Simonetti; Altino Ribeiro Leitão

    2009-01-01

    Because their services are based decisively on the collection, analysis and exchange of clinical information or knowledge, within and across organizational boundaries, knowledge management has exceptional application and importance to health care organizations. This article proposes a conceptual framework for a knowledge management system, which is expected to support both hospitals and the oncology network in Brazil. Under this holistic single-case study, triangulation of multiple sources of...

  17. PRESENTATION: ARCHITECTURE, ARCHAEOLOGY AND CONTEMPORARY CITY PLANNING “State of knowledge in the digital age”

    OpenAIRE

    Giorgio VERDIANI; Cornell, Per; Rodriguez-Navarro, Pablo

    2015-01-01

    In discussions on urbanism, the need to involve new actors has been a major theme of recent debate. In this field, throughout Europe, various ways of allowing citizens to take a more direct part in planning is stressed. It is also important to look at the role or lack of role played by particular research fields. Architecture plays a major role in city planning. While archaeology has become increasingly involved in field projects in urban environments, the discipline seldom plays an important...

  18. Dynamic brain architectures in local brain activity and functional network efficiency associate with efficient reading in bilinguals.

    Science.gov (United States)

    Feng, Gangyi; Chen, Hsuan-Chih; Zhu, Zude; He, Yong; Wang, Suiping

    2015-10-01

    The human brain is organized as a dynamic network, in which both regional brain activity and inter-regional connectivity support high-level cognitive processes, such as reading. However, it is still largely unknown how the functional brain network organizes to enable fast and effortless reading processing in the native language (L1) but not in a non-proficient second language (L2), and whether the mechanisms underlying local activity are associated with connectivity dynamics in large-scale brain networks. In the present study, we combined activation-based and multivariate graph-theory analysis with functional magnetic resonance imaging data to address these questions. Chinese-English unbalanced bilinguals read narratives for comprehension in Chinese (L1) and in English (L2). Compared with L2, reading in L1 evoked greater brain activation and recruited a more globally efficient but less clustered network organization. Regions with both increased network efficiency and enhanced brain activation in L1 reading were mostly located in the fronto-temporal reading-related network (RN), whereas regions with decreased global network efficiency, increased clustering, and more deactivation in L2 reading were identified in the default mode network (DMN). Moreover, functional network efficiency was closely associated with local brain activation, and such associations were also modulated by reading efficiency in the two languages. Our results demonstrate that an economical and integrative brain network topology is associated with efficient reading, and further reveal a dynamic association between network efficiency and local activation for both RN and DMN. These findings underscore the importance of considering interregional connectivity when interpreting local BOLD signal changes in bilingual reading. PMID:26095088

  19. An Integrated Knowledge Base System Architecture for Histopathological Diagnosis of Breast Diseases

    OpenAIRE

    Aderonke A Kayode; Babajide S.Afolabi; Adelusola, Kayode A

    2012-01-01

    The histopathological diagnosis of breast diseases requires highly trained and experienced experts, and often strains pathologists’ cognitive capabilities. Accurate and timely diagnosis of breast diseases is essential for the appropriate management of the patients. The paper presents a knowledge base system that uses a combination of rule-based and case-based techniques to achieve the diagnosis. Rule-based systems handle problems with well-defined knowledge bases this limits the flexibility o...

  20. Architectural Design Decisions For A Knowledge-Based Distributed Systems Manager

    Science.gov (United States)

    Pasquale, Joseph

    1987-05-01

    A major fundamental problem in decentralized resource control in distributed systems is that in general, no decision-making node knows with complete certainty the current global state of the system. We present an architecture for an Expert Manager which provides a framework for dealing with this problem. Expert system techniques are used to infer the global system state using whatever partial state information is at hand, along with mechanisms for reasoning. Decision-making is enhanced by taking into account the uncertainty of observations, and that concurrent decisions made by many Expert Managers may conflict.

  1. The Application of Integrated Knowledge-based Systems for the Biomedical Risk Assessment Intelligent Network (BRAIN)

    Science.gov (United States)

    Loftin, Karin C.; Ly, Bebe; Webster, Laurie; Verlander, James; Taylor, Gerald R.; Riley, Gary; Culbert, Chris; Holden, Tina; Rudisill, Marianne

    1993-01-01

    One of NASA's goals for long duration space flight is to maintain acceptable levels of crew health, safety, and performance. One way of meeting this goal is through the Biomedical Risk Assessment Intelligent Network (BRAIN), an integrated network of both human and computer elements. The BRAIN will function as an advisor to flight surgeons by assessing the risk of in-flight biomedical problems and recommending appropriate countermeasures. This paper describes the joint effort among various NASA elements to develop BRAIN and an Infectious Disease Risk Assessment (IDRA) prototype. The implementation of this effort addresses the technological aspects of the following: (1) knowledge acquisition; (2) integration of IDRA components; (3) use of expert systems to automate the biomedical prediction process; (4) development of a user-friendly interface; and (5) integration of the IDRA prototype and Exercise Countermeasures Intelligent System (ExerCISys). Because the C Language, CLIPS (the C Language Integrated Production System), and the X-Window System were portable and easily integrated, they were chosen as the tools for the initial IDRA prototype. The feasibility was tested by developing an IDRA prototype that predicts the individual risk of influenza. The application of knowledge-based systems to risk assessment is of great market value to the medical technology industry.

  2. "The architecture of access to scientific knowledge: just how badly we have messed this up"

    CERN Document Server

    CERN. Geneva

    2011-01-01

    In this talk, Professor Lessig will review the evolution of access to scientific scholarship, and evaluate the success of this system of access against a background norm of universal access.While copyright battles involving artists has gotten most of the public's attention, the real battle should be over access to knowledge, not culture. That battle we are losing.

  3. The adult brain tissue response to hollow fiber membranes of varying surface architecture with or without cotransplanted cells

    Science.gov (United States)

    Zhang, Ning

    A variety of biomaterials have been chronically implanted into the central nervous system (CNS) for repair or therapeutic purposes. Regardless of the application, chronic implantation of materials into the CNS induces injury and elicits a wound healing response, eventually leading to the formation of a dense extracellular matrix (ECM)-rich scar tissue that is associated with the segregation of implanted materials from the surrounding normal tissue. Often this reaction results in impaired performance of indwelling CNS devices. In order to enhance the performance of biomaterial-based implantable devices in the CNS, this thesis investigated whether adult brain tissue response to implanted biomaterials could be manipulated by changing biomaterial surface properties or further by utilizing the biology of co-transplanted cells. Specifically, the adult rat brain tissue response to chronically implanted poly(acrylonitrile-vinylchloride) (PAN-PVC) hollow fiber membranes (HFMs) of varying surface architecture were examined temporally at 2, 4, and 12 weeks postimplantation. Significant differences were discovered in the brain tissue response to the PAN-PVC HFMs of varying surface architecture at 4 and 12 weeks. To extend this work, whether the soluble factors derived from a co-transplanted cellular component further affect the brain tissue response to an implanted HFM in a significant way was critically exploited. The cells used were astrocytes, whose ability to influence scar formation process following CNS injury by physical contact with the host tissue had been documented in the literature. Data indicated for the first time that astrocyte-derived soluble factors ameliorate the adult brain tissue reactivity toward HFM implants in an age-dependent manner. While immature astrocytes secreted soluble factors that suppressed the brain tissue reactivity around the implants, mature astrocytes secreted factors that enhanced the gliotic response. These findings prove the feasibility

  4. A Semantic-Oriented Architecture of a Functional Module for Personalized and Adaptive Access to the Knowledge in a Multimedia Digital Library

    OpenAIRE

    Paneva-Marinova, Desislava

    2008-01-01

    This article presents the principal results of the doctoral thesis “Semantic-oriented Architecture and Models for Personalized and Adaptive Access to the Knowledge in Multimedia Digital Library” by Desislava Ivanova Paneva-Marinova (Institute of Mathematics and Informatics), successfully defended before the Specialised Academic Council for Informatics and Mathematical Modelling on 27 October, 2008. This paper presents dissertation work on semantic-oriented architectures and...

  5. DESIGNING A KNOWLEDGE MANAGEMENT ARCHITECTURE TO SUPPORT SELF-ORGANIZATION IN A HOTEL CHAIN

    OpenAIRE

    Kaldis, Emmanuel

    2012-01-01

    Models are incredibly insidious; they slide undetected into discussions and then dominate the way people think. Since Information Systems (ISs) and particularly Knowledge Management Systems (KMSs) are socio-technical systems, they unconsciously embrace the characteristics of the dominant models of management thinking. Thus, their limitations can often be attributed to the deficiencies of the organizational models they aim to support. Through the case study of a hotel chain, this research sugg...

  6. An Integrated Knowledge Base System Architecture for Histopathological Diagnosis of Breast Diseases

    Directory of Open Access Journals (Sweden)

    Aderonke A. Kayode

    2012-12-01

    Full Text Available The histopathological diagnosis of breast diseases requires highly trained and experienced experts, and often strains pathologists’ cognitive capabilities. Accurate and timely diagnosis of breast diseases is essential for the appropriate management of the patients. The paper presents a knowledge base system that uses a combination of rule-based and case-based techniques to achieve the diagnosis. Rule-based systems handle problems with well-defined knowledge bases this limits the flexibility of such system. Case-based reasoning has been adopted to overcome this inherent weakness of rule-based systems by incorporating previous cases in the generation of new cases to improve the performance of the system. The result of this research shows that the system is capable of assisting pathologists in making accurate, consistent and timely diagnoses. The system also aid in eliminating errors of omission that have been viewed as a prominent cause of medical errors. In conclusion this paper investigated the histological features used in the diagnosis of breast diseases and proposed an integrated knowledge base system based on the features.

  7. Fragmentation: loss of global coherence or breakdown of modularity in functional brain architecture?

    OpenAIRE

    Daan van den Berg; Pulin Gong; Michael Breakspear; Cees van Leeuwen

    2012-01-01

    Psychiatric illnesses characterised by disorganized cognition, such as schizophrenia, have been described in terms of fragmentation and hence understood as reduction in functional brain connectivity, particularly in prefrontal and parietal areas. However, as graph-theory shows, relatively small numbers of nonlocal connections are sufficient to ensure global coherence in the modular small world network structure of the brain. We reconsider fragmentation in this perspective. Computational studi...

  8. ASSESSING THE FUNCTIONAL ARCHITECTURE OF THE BRAIN WITH DIFFUSION MRI IN PAEDIATRIC PATIENTS

    OpenAIRE

    AMINOV KHABIBULLA

    2015-01-01

    The paper presents the results of the evaluation with MRI diffusion in the diagnosis of structural brain damage in children with symptomatic epilepsy in the background of developmental abnormalities of the brain and comparison of changes detected with routine MRI parameters. We studied parameters of MR diffusion weighted imaging in symptomatic epilepsy paediatric patients and determined the quantitative standards of numerical values of diffusion of white matter in children with symptomatic ep...

  9. A functional architecture of the human brain: Emerging insights from the science of emotion

    OpenAIRE

    Lindquist, Kristen A; Barrett, Lisa Feldman

    2012-01-01

    The ‘faculty psychology’ approach to the mind, which attempts to explain mental function in terms of categories that reflect modular ‘faculties’, such as emotions, cognitions, and perceptions, has dominated research into the mind and its physical correlates. In this paper, we argue that brain organization does not respect the commonsense categories belonging to the faculty psychology approach. We review recent research from the science of emotion demonstrating that the human brain contains br...

  10. Linking human brain local activity fluctuations to structural and functional network architectures

    OpenAIRE

    Baria, A.T.; Mansour, A; Huang, L.; Baliki, M. N.; Cecchi, G. A.; Mesulam, M M; A. V. Apkarian

    2013-01-01

    Activity of cortical local neuronal populations fluctuates continuously, and a large proportion of these fluctuations are shared across populations of neurons. Here we seek organizational rules that link these two phenomena. Using neuronal activity, as identified by functional MRI (fMRI) and for a given voxel or brain region, we derive a single measure of full bandwidth brain-oxygenation-level-dependent (BOLD) fluctuations by calculating the slope, α, for the log-linear power spectrum. For th...

  11. Combined Cognitive-Psychological-Physical Intervention Induces Reorganization of Intrinsic Functional Brain Architecture in Older Adults

    Directory of Open Access Journals (Sweden)

    Zhiwei Zheng

    2015-01-01

    Full Text Available Mounting evidence suggests that enriched mental, physical, and socially stimulating activities are beneficial for counteracting age-related decreases in brain function and cognition in older adults. Here, we used functional magnetic resonance imaging (fMRI to demonstrate the functional plasticity of brain activity in response to a combined cognitive-psychological-physical intervention and investigated the contribution of the intervention-related brain changes to individual performance in healthy older adults. The intervention was composed of a 6-week program of combined activities including cognitive training, Tai Chi exercise, and group counseling. The results showed improved cognitive performance and reorganized regional homogeneity of spontaneous fluctuations in the blood oxygen level-dependent (BOLD signals in the superior and middle temporal gyri, and the posterior lobe of the cerebellum, in the participants who attended the intervention. Intriguingly, the intervention-induced changes in the coherence of local spontaneous activity correlated with the improvements in individual cognitive performance. Taken together with our previous findings of enhanced resting-state functional connectivity between the medial prefrontal cortex and medial temporal lobe regions following a combined intervention program in older adults, we conclude that the functional plasticity of the aging brain is a rather complex process, and an effective cognitive-psychological-physical intervention is helpful for maintaining a healthy brain and comprehensive cognition during old age.

  12. Investigating dynamical information transfer in the brain following a TMS pulse: Insights from structural architecture.

    Science.gov (United States)

    Amico, Enrico; Van Mierlo, Pieter; Marinazzo, Daniele; Laureys, Steven

    2015-01-01

    Transcranial magnetic stimulation (TMS) has been used for more than 20 years to investigate connectivity and plasticity in the human cortex. By combining TMS with high-density electroencephalography (hd-EEG), one can stimulate any cortical area and measure the effects produced by this perturbation in the rest of the cerebral cortex. The purpose of this paper is to investigate changes of information flow in the brain after TMS from a functional and structural perspective, using multimodal modeling of source reconstructed TMS/hd-EEG recordings and DTI tractography. We prove how brain dynamics induced by TMS is constrained and driven by its structure, at different spatial and temporal scales, especially when considering cross-frequency interactions. These results shed light on the function-structure organization of the brain network at the global level, and on the huge variety of information contained in it. PMID:26737511

  13. Macroscopic brain architecture changes and white matter pathology in acromegaly: a clinicoradiological study

    OpenAIRE

    Sievers, C.; Sämann, P. G.; T. Dose; Dimopoulou, C.; Spieler, D.; Roemmler, J.; Schopohl, J.; Mueller, M.; Schneider, H. J.; Czisch, M.; Pfister, H; Stalla, G K

    2008-01-01

    Although long-term exposure of the brain to increased GH/IGF-1 likely influences cerebral functions, no in vivo studies have been directed towards changes of the brain structure in acromegaly. Here, we used high resolution magnetic resonance images to compare volumes of gray matter (GM), white matter (WM) and cerebrospinal fluid (CSF) of forty-four patients with acromegaly to an age and gender matched, healthy control group (n = 44). In addition, white matter lesions (WMLs) were quantified an...

  14. Brain architecture in the terrestrial hermit crab Coenobita clypeatus (Anomura, Coenobitidae, a crustacean with a good aerial sense of smell

    Directory of Open Access Journals (Sweden)

    Hansson Bill S

    2008-06-01

    Full Text Available Abstract Background During the evolutionary radiation of Crustacea, several lineages in this taxon convergently succeeded in meeting the physiological challenges connected to establishing a fully terrestrial life style. These physiological adaptations include the need for sensory organs of terrestrial species to function in air rather than in water. Previous behavioral and neuroethological studies have provided solid evidence that the land hermit crabs (Coenobitidae, Anomura are a group of crustaceans that have evolved a good sense of aerial olfaction during the conquest of land. We wanted to study the central olfactory processing areas in the brains of these organisms and to that end analyzed the brain of Coenobita clypeatus (Herbst, 1791; Anomura, Coenobitidae, a fully terrestrial tropical hermit crab, by immunohistochemistry against synaptic proteins, serotonin, FMRFamide-related peptides, and glutamine synthetase. Results The primary olfactory centers in this species dominate the brain and are composed of many elongate olfactory glomeruli. The secondary olfactory centers that receive an input from olfactory projection neurons are almost equally large as the olfactory lobes and are organized into parallel neuropil lamellae. The architecture of the optic neuropils and those areas associated with antenna two suggest that C. clypeatus has visual and mechanosensory skills that are comparable to those of marine Crustacea. Conclusion In parallel to previous behavioral findings of a good sense of aerial olfaction in C. clypeatus, our results indicate that in fact their central olfactory pathway is most prominent, indicating that olfaction is a major sensory modality that these brains process. Interestingly, the secondary olfactory neuropils of insects, the mushroom bodies, also display a layered structure (vertical and medial lobes, superficially similar to the lamellae in the secondary olfactory centers of C. clypeatus. More detailed analyses with

  15. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen

    This PhD thesis is motived by a personal interest in the theoretical, practical and creative qualities of architecture. But also a wonder and curiosity about the cultural and social relations architecture represents through its occupation with both the sciences and the arts. Inspired by present...... initiatives in Aalborg Hospital to overcome patient undernutrition by refurbishing eating environments, this thesis engages in an investigation of the interior architectural qualities of patient eating environments. The relevance for this holistic perspective, synthesizing health, food and architecture, is...... the current building of a series of Danish ‘super hospitals’ and an increased focus among architectural practices on research-based knowledge produced with the architectural sub-disciplines Healing Architecture and Evidence-Based Design. The problem is that this research does not focus on patient...

  16. Integration of Structural Knowledge in Design Studio Project: Assessment Study of Curriculum In Architecture Course in University Of Malaya

    OpenAIRE

    Aniza Abdul Aziz; Maha Mohani Fahmi; Lim Take Bane

    2010-01-01

    Architectural education should advance in parallel with the industrial growth of building technology. Universities as producers of future architects have yet to develop curriculums for building technology to suit the growth of the building industry. This gap between education and industrial growth has been a topic of debate for many researchers who are concerned about architectural pedagogy. Architectural instruction further aggravated the problem whereby in most architectural schools worldwi...

  17. Novel theory of the human brain: information-commutation basis of architecture and principles of operation

    OpenAIRE

    Bryukhovetskiy AS

    2015-01-01

    Andrey S Bryukhovetskiy Center for Biomedical Technologies, Federal Research and Clinical Center for Specialized Types of Medical Assistance and Medical Technologies of the Federal Medical Biological Agency, NeuroVita Clinic of Interventional and Restorative Neurology and Therapy, Moscow, Russia Abstract: Based on the methodology of the informational approach and research of the genome, proteome, and complete transcriptome profiles of different cells in the nervous tissue of the human brain,...

  18. Functional Genomic Architecture of Predisposition to Voluntary Exercise in Mice: Expression QTL in the Brain

    OpenAIRE

    Kelly, Scott A.; Nehrenberg, Derrick L.; Hua, Kunjie; Garland, Theodore; Pomp, Daniel

    2012-01-01

    The biological basis of voluntary exercise is complex and simultaneously controlled by peripheral (ability) and central (motivation) mechanisms. The accompanying natural reward, potential addiction, and the motivation associated with exercise are hypothesized to be regulated by multiple brain regions, neurotransmitters, peptides, and hormones. We generated a large (n = 815) advanced intercross line of mice (G4) derived from a line selectively bred for increased wheel running (high runner) and...

  19. “Do Octopuses Have a Brain?” Knowledge, Perceptions and Attitudes towards Neuroscience at School

    OpenAIRE

    Alessandra Sperduti; Federica Crivellaro; Paola Francesca Rossi; Luca Bondioli

    2012-01-01

    The present study contributes to the question of school literacy about the brain, with an original survey conducted on Italian students from the 3(rd) to 10(th) grades (n=508). The main goal was to test student's knowledge, attitudes, and interests about neuroscience, to assess needs, prospects, and difficulties in teaching about the brain from elementary to high school. A written questionnaire, maintaining anonymity, asked 12 close-ended multiple choice questions on topics related to human a...

  20. Harnessing the Risk-Related Data Supply Chain: An Information Architecture Approach to Enriching Human System Research and Operations Knowledge

    Science.gov (United States)

    Buquo, Lynn; Johnson-Throop, Kathy

    2010-01-01

    NASA's Human Research Program (HRP) and Space Life Sciences Directorate (SLSD), not unlike many NASA organizations today, struggle with the inherent inefficiencies caused by dependencies on heterogeneous data systems and silos of data and information spread across decentralized discipline domains. The capture of operational and research-based data/information (both in-flight and ground-based) in disparate IT systems impedes the extent to which that data/information can be efficiently and securely shared, analyzed, and enriched into knowledge that directly and more rapidly supports HRP's research-focused human system risk mitigation efforts and SLSD s operationally oriented risk management efforts. As a result, an integrated effort is underway to more fully understand and document how specific sets of risk-related data/information are generated and used and in what IT systems that data/information currently resides. By mapping the risk-related data flow from raw data to useable information and knowledge (think of it as the data supply chain), HRP and SLSD are building an information architecture plan to leverage their existing, shared IT infrastructure. In addition, it is important to create a centralized structured tool to represent risks including attributes such as likelihood, consequence, contributing factors, and the evidence supporting the information in all these fields. Representing the risks in this way enables reasoning about the risks, e.g. revisiting a risk assessment when a mitigation strategy is unavailable, updating a risk assessment when new information becomes available, etc. Such a system also provides a concise way to communicate the risks both within the organization as well as with collaborators. Understanding and, hence, harnessing the human system risk-related data supply chain enhances both organizations' abilities to securely collect, integrate, and share data assets that improve human system research and operations.

  1. Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms.

    Science.gov (United States)

    Smith, J C; Abdala, A P L; Koizumi, H; Rybak, I A; Paton, J F R

    2007-12-01

    Mammalian central pattern generators (CPGs) producing rhythmic movements exhibit extremely robust and flexible behavior. Network architectures that enable these features are not well understood. Here we studied organization of the brain stem respiratory CPG. By sequential rostral to caudal transections through the pontine-medullary respiratory network within an in situ perfused rat brain stem-spinal cord preparation, we showed that network dynamics reorganized and new rhythmogenic mechanisms emerged. The normal three-phase respiratory rhythm transformed to a two-phase and then to a one-phase rhythm as the network was reduced. Expression of the three-phase rhythm required the presence of the pons, generation of the two-phase rhythm depended on the integrity of Bötzinger and pre-Bötzinger complexes and interactions between them, and the one-phase rhythm was generated within the pre-Bötzinger complex. Transformation from the three-phase to a two-phase pattern also occurred in intact preparations when chloride-mediated synaptic inhibition was reduced. In contrast to the three-phase and two-phase rhythms, the one-phase rhythm was abolished by blockade of persistent sodium current (I(NaP)). A model of the respiratory network was developed to reproduce and explain these observations. The model incorporated interacting populations of respiratory neurons within spatially organized brain stem compartments. Our simulations reproduced the respiratory patterns recorded from intact and sequentially reduced preparations. Our results suggest that the three-phase and two-phase rhythms involve inhibitory network interactions, whereas the one-phase rhythm depends on I(NaP). We conclude that the respiratory network has rhythmogenic capabilities at multiple levels of network organization, allowing expression of motor patterns specific for various physiological and pathophysiological respiratory behaviors. PMID:17913982

  2. Software architecture

    CERN Document Server

    Vogel, Oliver; Chughtai, Arif

    2011-01-01

    As a software architect you work in a wide-ranging and dynamic environment. You have to understand the needs of your customer, design architectures that satisfy both functional and non-functional requirements, and lead development teams in implementing the architecture. And it is an environment that is constantly changing: trends such as cloud computing, service orientation, and model-driven procedures open up new architectural possibilities. This book will help you to develop a holistic architectural awareness and knowledge base that extends beyond concrete methods, techniques, and technologi

  3. Functional specificity in the human brain: A window into the functional architecture of the mind

    OpenAIRE

    Kanwisher, Nancy

    2010-01-01

    Is the human mind/brain composed of a set of highly specialized components, each carrying out a specific aspect of human cognition, or is it more of a general-purpose device, in which each component participates in a wide variety of cognitive processes? For nearly two centuries, proponents of specialized organs or modules of the mind and brain—from the phrenologists to Broca to Chomsky and Fodor—have jousted with the proponents of distributed cognitive and neural processing—from Flourens to L...

  4. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen

    initiatives in Aalborg Hospital to overcome patient undernutrition by refurbishing eating environments, this thesis engages in an investigation of the interior architectural qualities of patient eating environments. The relevance for this holistic perspective, synthesizing health, food and architecture...... environments and a knowledge gap therefore exists in present hospital designs. Consequently, the purpose of this thesis has been to investigate if any research-based knowledge exist supporting the hypothesis that the interior architectural qualities of eating environments influence patient food intake, health...... such as a literature review, timeline and historical outline to create a “knowledge map”, which in an eclectic manner merges the positive, normative and polemical knowledge rooted in research, objects and writings. The results of these investigations show that sparse researchbased knowledge exist directly taking...

  5. Fragmentation: Loss of global coherence or breakdown of modularity in functional brain architecture?

    Directory of Open Access Journals (Sweden)

    Daan van den Berg

    2012-03-01

    Full Text Available Psychiatric illnesses characterised by disorganized cognition, such as schizophrenia, have been described in terms of fragmentation and hence understood as reduction in functional brain connectivity, particularly in prefrontal and parietal areas. However, as graph-theory shows, relatively small numbers of nonlocal connections are sufficient to ensure global coherence in the modular small world network structure of the brain. We reconsider fragmentation in this perspective. Computational studies have shown that for a given level of connectivity in a model of coupled nonlinear oscillators, modular small-world networks evolve from an initially random organization. Here we demonstrate that with decreasing connectivity, the probability of evolving into a modular small-world network breaks down at a critical point, which scales to the percolation function of random networks with a universal exponent of α=1.17. Thus, according to the model, local modularity systematically breaks down before there is loss of global coherence in network connectivity. We therefore propose that fragmentation may involve, at least in its initial stages, the inability of a dynamically evolving network to sustain a modular small-world structure. The result is in a shift in the balance in schizophrenia from local to global functional connectivity.

  6. The HealthAgents Ontology: How to Represent the Knowledge behind a Brain Tumour Distributed Decision System

    OpenAIRE

    Hu, Bo; Croitoru, Madalina; Roset, Roman; David, Dupplaw; Miguel, Lurgi; Srinandan, Dasmahapatra; Lewis, Paul; Martinez-Miranda, Juan; Saez, Carlos

    2011-01-01

    In this paper we present our experience of representing the knowledge behind HealthAgents, a distributed decision support system for brain tumour diagnosis. Our initial motivation came from the distributed nature of the information involved in the system and has been enriched by clinicians' requirements and data access restrictions. We present in detail the steps we have taken towards building our ontology starting from knowledge acquisition to data access and reasoning. We motivate our repre...

  7. Intersecting Knowledge Fields and Integrating Data-Driven Computational Design en Route to Performance-Oriented and Intensely Local Architectures

    OpenAIRE

    Hensel, Michael U.; Sørensen, Søren S.

    2014-01-01

    This paper discusses research by design efforts in architectural education, focused on developing concepts and methods for the design of performance-oriented and intensely local architectures. The pursued notion of performance foregrounds the interaction between a given architecture and its local setting, with consequences not only for the design product but also for the related processes by which it is generated. Integrated approaches to data-driven computational design serve to generate suc...

  8. Researching the Practice, Practicing the Research, and Promoting Responsible Policy: Usable Knowledge in Mind, Brain, and Education

    Science.gov (United States)

    Christodoulou, Joanna A.; Daley, Samantha G.; Katzir, Tami

    2009-01-01

    The theme of Usable Knowledge in Mind, Brain, and Education will be a special section that will appear regularly in the journal. The section will focus on the synergistic connections between biology, cognitive science, and human development on the one hand and educational thought, policy, and practice on the other. Efforts to create usable…

  9. Object recognition in brain CT-scans: Knowledge-based fusion of data from multiple feature extractors

    International Nuclear Information System (INIS)

    This paper describes a knowledge-based image interpretation system for the segmentation and labeling of a series of 2-D brain X-ray CT-scans, parallel to the orbito-metal plane. The system combines the image primitive information produced by different low level vision techniques in order to improve the reliability of the segmentation and the image interpretation. It is implemented in a blackboard environment that is holding various types of prior information and which controls the interpretation process. The scoring model is applied for the fusion of information derived from three types of image primitives (points, edges, and regions). A model, containing both analogical and propositional knowledge on the brain objects, is used to direct the interpretation process. The linguistic variables, introduced to describe the propositional features of the brain model, are defined by fuzzy membership functions. Constraint functions are applied to evaluate the plausibility of the mapping between image primitives and brain model data objects. Procedural knowledge has been integrated into different knowledge sources. Experimental results illustrate the reliability and robustness of the system against small variations in slice orientation and interpatient variability in the images

  10. Teaching History of Architecture--Moving from a Knowledge Transfer to a Multi-Participative Methodology Based on IT Tools

    Science.gov (United States)

    Cimadomo, Guido

    2014-01-01

    The changes that the European Higher Education Area (EHEA) framework obliged the School of Architecture of Malaga, University of Malaga. to make to its "History of Architecture" course are discussed in this paper. It was taken up as an opportunity to modify the whole course, introducing creative teaching and "imaginative…

  11. Intersecting Knowledge Fields and Integrating Data-Driven Computational Design en Route to Performance-Oriented and Intensely Local Architectures

    Directory of Open Access Journals (Sweden)

    Michael U Hensel

    2014-11-01

    Full Text Available This paper discusses research by design efforts in architectural education, focused on developing concepts and methods for the design of performance-oriented and intensely local architectures. The pursued notion of performance foregrounds the interaction between a given architecture and its local setting, with consequences not only for the design product but also for the related processes by which it is generated. Integrated approaches to data-driven computational design serve to generate such designs. The outlined approach shifts the focus of design attention away from the delivery of finite architectural objects and towards an expanded range of architecture-environment interactions that are registered, instrumentalised and modulated over time. This paper examines ongoing efforts in integrating specific architectural goals and approaches, computational data-driven design methods and generative design processes, based on a range of context-specific and often real-time data sets. The work discussed is produced in the context of the Research Centre for Architecture and Tectonics (RCAT and the Advanced Computational Design Laboratory (ACDL at the Oslo School of Architecture and Design.

  12. Brain

    Science.gov (United States)

    ... will return after updating. Resources Archived Modules Updates Brain Cerebrum The cerebrum is the part of the ... the outside of the brain and spinal cord. Brain Stem The brain stem is the part of ...

  13. Programming the brain: Common outcomes and gaps in knowledge from animal studies of IUGR.

    Science.gov (United States)

    Hunter, Damien S; Hazel, Susan J; Kind, Karen L; Owens, Julie A; Pitcher, Julia B; Gatford, Kathryn L

    2016-10-01

    IUGR in humans is associated with impaired pre- and postnatal neurodevelopment, and subsequent postnatal cognition, resulting in lower IQ, poorer memory, visuomotor and executive function skills, as well as behavioural and attentional problems. Experimental models of IUGR are needed to allow direct testing of causality and interventions, and have benefits in reducing both confounding by comorbidities such as prematurity, and variation due to environment and genetics. This review describes and discusses experimental models of IUGR in which neurodevelopmental and cognitive outcomes of IUGR have been reported. We consider the timing of neurodevelopment relative to birth and to the period of restriction, as well as the effects of each experimental perturbation on the fetal environment and development, before discussing neurodevelopmental and cognitive outcomes for progeny as fetuses, neonates and into adolescent and adult life. Experimental IUGR induces broadly similar outcomes to human IUGR, with altered brain morphology, in particular grey matter loss and discordant trajectory of white matter development, and poorer cognition and memory reported in various studies. Nevertheless, there remain gaps in knowledge of neurodevelopment in experimental models. We end the review with recommendations for the design of future studies to further investigate the mechanisms underlying adverse neurodevelopmental consequences of IUGR, and to evaluate interventions that may subsequently improve outcomes of IUGR in humans. PMID:27288225

  14. Handbook of Brain Connectivity

    CERN Document Server

    Jirsa, Viktor K

    2007-01-01

    Our contemporary understanding of brain function is deeply rooted in the ideas of the nonlinear dynamics of distributed networks. Cognition and motor coordination seem to arise from the interactions of local neuronal networks, which themselves are connected in large scales across the entire brain. The spatial architectures between various scales inevitably influence the dynamics of the brain and thereby its function. But how can we integrate brain connectivity amongst these structural and functional domains? Our Handbook provides an account of the current knowledge on the measurement, analysis and theory of the anatomical and functional connectivity of the brain. All contributors are leading experts in various fields concerning structural and functional brain connectivity. In the first part of the Handbook, the chapters focus on an introduction and discussion of the principles underlying connected neural systems. The second part introduces the currently available non-invasive technologies for measuring struct...

  15. Neurally and Mathematically Motivated Architecture for Language and Thought

    OpenAIRE

    Perlovsky, L.I; Ilin, R

    2010-01-01

    Neural structures of interaction between thinking and language are unknown. This paper suggests a possible architecture motivated by neural and mathematical considerations. A mathematical requirement of computability imposes significant constraints on possible architectures consistent with brain neural structure and with a wealth of psychological knowledge. How language interacts with cognition. Do we think with words, or is thinking independent from language with words being just labels for ...

  16. On Using Knowledge about Our Brain: A Conversation with Bob Sylwester.

    Science.gov (United States)

    Brandt, Ron

    1997-01-01

    Today, researchers can learn about blood flow, electromagnetic fields, and chemical composition of the brain by using functional MRI (magnetic resonance imaging). As biologists, medical researchers, and cognitive scientists learn more about brain functions, educators must keep informed, study, and apply what they have learned in the classroom.…

  17. Knowledges

    DEFF Research Database (Denmark)

    Berling, Trine Villumsen

    2012-01-01

    Scientific knowledge in international relations has generally focused on an epistemological distinction between rationalism and reflectivism over the last 25 years. This chapter argues that this distinction has created a double distinction between theory/reality and theory/practice, which works as...... a ghost distinction structuring IR research. While reflectivist studies have emphasised the impossibility of detached, objective knowledge production through a dissolution of the theory/reality distinction, the theory/practice distinction has been left largely untouched by both rationalism and...... reflectivism. Bourdieu, on the contrary, lets the challenge to the theory/reality distinction spill over into a challenge to the theory/practice distinction by thrusting the scientist in the foreground as not just a factor (discourse/genre) but as an actor. In this way, studies of IR need to include a focus on...

  18. From Data towards Knowledge: Revealing the Architecture of Signaling Systems by Unifying Knowledge Mining and Data Mining of Systematic Perturbation Data

    OpenAIRE

    Songjian Lu; Bo Jin; L Ashley Cowart; Xinghua Lu

    2013-01-01

    Genetic and pharmacological perturbation experiments, such as deleting a gene and monitoring gene expression responses, are powerful tools for studying cellular signal transduction pathways. However, it remains a challenge to automatically derive knowledge of a cellular signaling system at a conceptual level from systematic perturbation-response data. In this study, we explored a framework that unifies knowledge mining and data mining approaches towards the goal. The framework consists of the...

  19. DeSyGNER: A Building Block Architecture Fostering Independent Cooperative Development of Multimedia Knowledge Management Applications

    OpenAIRE

    Deibel, Stephan R.A.; Greenes, Robert A.; Snydr-Michal, Jan T.

    1990-01-01

    Multimedia knowledge management requires generalized sharing, composition and inter-relation of disparate data and knowledge elements. Since traditional computer operating systems treat programs as bodies of isolated functionality, inter-program connections can be made only by considerable effort on the part of each program author. We have been developing a multimedia kernel called DeSyGNER (the Decision Systems Group Nucleus of Extensible Resources) that provides basic multimedia knowledge m...

  20. Research on ontology-based architectural knowledge management for software-intensive systems%基于本体的软件密集型系统架构知识管理研究

    Institute of Scientific and Technical Information of China (English)

    张纯; 张敬周; 宋俊典

    2011-01-01

    To solve the vaporization of architectural knowledge, an ontology-based management framework is brought forward. First,the classification of architectural knowledge is analyzed. Based on the analysis, an ontology model of architectural knowledge is proposed,which elaborates the meaning of and interrelationship among architectural problems, architectural design decisions and architecture design. In addition, a management framework covering the acquisition, documentation, assessment, repository and reuse of the architectural knowledge is brought forward to achieve the full management, sharing and reuse of them.%为了解决架构知识蒸发的问题,提出了一种基于本体的架构知识管理框架.分析了该架构知识的分类,在此基础上从架构问题、架构设计决策和软件架构等3方面构建一个架构知识本体模型,并且描述了这3类架构知识的内涵及其相互关系,进而提出一个架构知识管理框架,能覆盖架构知识获取、编档、评价、存储和复用等过程,实现了架构知识的全面管理、共享和复用.

  1. How concepts are encoded in the human brain: A modality independent, category-based cortical organization of semantic knowledge.

    Science.gov (United States)

    Handjaras, Giacomo; Ricciardi, Emiliano; Leo, Andrea; Lenci, Alessandro; Cecchetti, Luca; Cosottini, Mirco; Marotta, Giovanna; Pietrini, Pietro

    2016-07-15

    How conceptual knowledge is represented in the human brain remains to be determined. To address the differential role of low-level sensory-based and high-level abstract features in semantic processing, we combined behavioral studies of linguistic production and brain activity measures by functional magnetic resonance imaging in sighted and congenitally blind individuals while they performed a property-generation task with concrete nouns from eight categories, presented through visual and/or auditory modalities. Patterns of neural activity within a large semantic cortical network that comprised parahippocampal, lateral occipital, temporo-parieto-occipital and inferior parietal cortices correlated with linguistic production and were independent both from the modality of stimulus presentation (either visual or auditory) and the (lack of) visual experience. In contrast, selected modality-dependent differences were observed only when the analysis was limited to the individual regions within the semantic cortical network. We conclude that conceptual knowledge in the human brain relies on a distributed, modality-independent cortical representation that integrates the partial category and modality specific information retained at a regional level. PMID:27132545

  2. A hybrid system using symbolic and numeric knowledge for the semantic annotation of sulco-gyral anatomy in brain MRI images.

    OpenAIRE

    Mechouche, Ammar; Morandi, Xavier; Golbreich, Christine; Gibaud, Bernard

    2009-01-01

    This paper describes an interactive system for the semantic annotation of brain magnetic resonance images. The system uses both a numerical atlas and symbolic knowledge of brain anatomical structures depicted using the Semantic Web standards. This knowledge is combined with graphical data, automatically extracted from the images by imaging tools. The annotations of parts of gyri and sulci, in a region of interest, rely on constraint satisfaction problem solving and description logics inferenc...

  3. On the Design of an Architecture for Partitioned Knowledge Management in Autonomic Multimedia Access and Aggregation Networks

    Science.gov (United States)

    Latré, Steven; Verstichel, Stijn; de Vleeschauwer, Bart; de Turck, Filip; Demeester, Piet

    The recent emergence of multimedia services, such as Network Based Personal Video Recording and Broadcast TV over traditional DSL based access networks, has introduced stringent Quality of Experience (QoE) requirements. It is generally assumed that the wide variety of services and user profiles introduces the need for a per-user or per-subscriber QoE management. Such a complex QoE management requires real-time knowledge about the managed services, which is available amongst the different nodes in the network. However, even for managing a few services, a relatively large amount of, constantly updated, knowledge is needed. Propagating all the knowledge to all nodes is therefore not feasible. As not all knowledge is relevant to all nodes, it is important to perform an intelligent knowledge distribution and management. In this position paper, we introduce the concept of a cognitive model that describes the knowledge requirements of each node. Based on the information stated in this cognitive model, we discuss how filter queries, that typically describe what needs to be queried from other nodes, can be automatically generated leading to an efficient partitioning of the knowledge through the distributed nodes.

  4. Awareness of deficits in traumatic brain injury: a multidimensional approach to assessing metacognitive knowledge and online-awareness.

    LENUS (Irish Health Repository)

    O'Keeffe, Fiadhnait

    2007-01-01

    Recent models of impaired awareness in brain injury draw a distinction between metacognitive knowledge of difficulties and online awareness of errors (emergent and anticipatory). We examined performance of 31 Traumatic Brain Injury (TBI) participants and 31 healthy controls using a three-strand approach to assessing awareness. Metacognitive knowledge was assessed with an awareness interview and discrepancy scores on three questionnaires--Patient Competency Rating Scale, Frontal Systems Behavioral Scale and the Cognitive Failures Questionnaire. Online Emergent Awareness was assessed using an online error-monitoring task while participants performed tasks of sustained attention. Online anticipatory awareness was examined using prediction performance on two cognitive tasks. Results indicated that the TBI Low Self-Awareness (SA) group and High SA group did not differ in terms of severity, chronicity or standard neuropsychological tasks but those with Low SA were more likely to exhibit disinhibition, interpersonal problems and more difficulties in total competency. Sustained attention abilities were associated with both types of online awareness (emergent and anticipatory). There was a strong relationship between online emergent and online anticipatory awareness. Metacognitive knowledge did not correlate with the other two measures. This study highlights the necessity in adopting a multidimensional approach to assessing the multifaceted phenomenon of awareness of deficits.

  5. Basicranial architecture and relative brain size of Sts 5 (Australopithecus africanus) and other Plio-Pleistocene hominids

    OpenAIRE

    Spoor, F.

    1997-01-01

    The cranial base has long been recognised as a complex morphological region where major structural changes have occurred during hominid evolution. Here the relationship between relative brain size and basicranial shape in modern humans, fossil hominids, Sts 5 in particular, and other primates is investigated. The results reveal that basicranial shape is well correlated with relative brain size among non-hominid primates, supporting the notion that brain size is a prime factor underlying bosic...

  6. Architecture - re-Construction - Geometry: a knowledge path applied to the study of Plantery's vaults in Turin

    Directory of Open Access Journals (Sweden)

    Roberta Spallone

    2012-06-01

    Full Text Available Plantery's vaults, by the name of the architect working in Turin since first years of '700, are composed by a main vault intersected by some axial and angular secondary vaults. Plantery's vaults allow to roof over unitary spaces obtaining effects of lightness also by small rises. Their diffusion, up to the '80s of the century, in boardrooms as palaces halls, and the richness of variations on the theme, justifies a research, that makes use of survey and digital modeling. This research is focused on the relationships between geometric models and built architecture, connected by use of materials, construction techniques and decorative styles.

  7. Territorial Innovation Dynamics: a Knowledge Based Perspective : A cross-analys of the I-space model and the architectural knowledge concept

    OpenAIRE

    Dang, Rani Jeanne; Roux, Karine; Longhi, Christian; Damien TALBOT (GREThA); Thomas, Catherine

    2014-01-01

    Many studies have focused on the role played by geographical location in the emergence and building of localised learning capacities (Maskell and Malmberg, 1999). In this perspective, empirical studies have demonstrated that the innovation dynamics of clusters result from the quality of interactions and coordination inside the cluster as well as interactions with external, often global, networks. In this context, knowledge exchange between firms and institutions are claimed to be the main dri...

  8. My brain knows numbers! - An ERP study of preschoolers’ numerical knowledge

    Directory of Open Access Journals (Sweden)

    TamarBen-Shalom

    2013-10-01

    Full Text Available This study investigated brain activity in numerical processing at early stages of development. Brain activity of preschoolers was obtained while they performed a numerical Stroop task. Participants were asked to decide which of two digits was numerically or physically larger. Behavioral distance and size congruity effects were found. However, a reverse facilitation was observed, where responses to neutral trials were faster than to congruent ones. Brain activity showed that 6-year-old children activate frontal areas related to conflict, as well as parietal areas related to mature numerical processing. Moreover, there was a difference between the timing of the interference compared to the facilitation components in the size congruity effect. In parietal areas, facilitation was significant in an early time window and interference was significant at a later time window. This is consistent with the idea that facilitation and interference are separate processes. Our findings indicate that children as young as 5-6 years old can automatically process the numerical meaning of numerals. In addition, brain activity during the numerical Stroop task showed that at this age, children use both frontal and parietal areas in order to process irrelevant numerical information.

  9. Images Are Not the (Only) Truth: Brain Mapping, Visual Knowledge, and Iconoclasm.

    Science.gov (United States)

    Beaulieu, Anne

    2002-01-01

    Debates the paradoxical nature of claims about the emerging contributions of functional brain mapping. Examines the various ways that images are deployed and rejected and highlights an approach that provides insight into the current demarcation of imaging. (Contains 68 references.) (DDR)

  10. Tacit Knowledge Capture and the Brain-Drain at Electrical Utilities

    Science.gov (United States)

    Perjanik, Nicholas Steven

    As a consequence of an aging workforce, electric utilities are at risk of losing their most experienced and knowledgeable electrical engineers. In this research, the problem was a lack of understanding of what electric utilities were doing to capture the tacit knowledge or know-how of these engineers. The purpose of this qualitative research study was to explore the tacit knowledge capture strategies currently used in the industry by conducting a case study of 7 U.S. electrical utilities that have demonstrated an industry commitment to improving operational standards. The research question addressed the implemented strategies to capture the tacit knowledge of retiring electrical engineers and technical personnel. The research methodology involved a qualitative embedded case study. The theories used in this study included knowledge creation theory, resource-based theory, and organizational learning theory. Data were collected through one time interviews of a senior electrical engineer or technician within each utility and a workforce planning or training professional within 2 of the 7 utilities. The analysis included the use of triangulation and content analysis strategies. Ten tacit knowledge capture strategies were identified: (a) formal and informal on-boarding mentorship and apprenticeship programs, (b) formal and informal off-boarding mentorship programs, (c) formal and informal training programs, (d) using lessons learned during training sessions, (e) communities of practice, (f) technology enabled tools, (g) storytelling, (h) exit interviews, (i) rehiring of retirees as consultants, and (j) knowledge risk assessments. This research contributes to social change by offering strategies to capture the know-how needed to ensure operational continuity in the delivery of safe, reliable, and sustainable power.

  11. Exposure to sublethal concentrations of a pesticide or predator cues induces changes in brain architecture in larval amphibians.

    Science.gov (United States)

    Woodley, Sarah K; Mattes, Brian M; Yates, Erika K; Relyea, Rick A

    2015-11-01

    Naturally occurring environmental factors shape developmental trajectories to produce variable phenotypes. Such developmental phenotypic plasticity can have important effects on fitness, and has been demonstrated for numerous behavioral and morphological traits. However, surprisingly few studies have examined developmental plasticity of the nervous system in response to naturally occurring environmental variation, despite accumulating evidence for neuroplasticity in a variety of organisms. Here, we asked whether the brain is developmentally plastic by exposing larval amphibians to natural and anthropogenic factors. Leopard frog tadpoles were exposed to predator cues, reduced food availability, or sublethal concentrations of the pesticide chlorpyrifos in semi-natural enclosures. Mass, growth, survival, activity, larval period, external morphology, brain mass, and brain morphology were measured in tadpoles and after metamorphosis. Tadpoles in the experimental treatments had lower masses than controls, although developmental rates and survival were similar. Tadpoles exposed to predator cues or a high dose of chlorpyrifos had altered body shapes compared to controls. In addition, brains from tadpoles exposed to predator cues or a low dose of chlorpyrifos were narrower and shorter in several dimensions compared to control tadpoles and tadpoles with low food availability. Interestingly, the changes in brain morphology present at the tadpole stage did not persist in the metamorphs. Our results show that brain morphology is a developmentally plastic trait that is responsive to ecologically relevant natural and anthropogenic factors. Whether these effects on brain morphology are linked to performance or fitness is unknown. PMID:26169394

  12. Self organization of understanding, consciousness, emotions and knowledge: Cell, brain, mind, sex, life

    OpenAIRE

    Souček, Branko

    2008-01-01

    Background and Purpose: This work develops the new intelligence Self Organization, SO; theory and practice. Materials and Methods: The experimental data and the theoretical results come from the animal and human cell, brain, mind and sex: firefly, katydid, frog, bird, rodent, human prefrontal cortex. Results: SO is a never ending, chaotic process that grows from the bottom up, without the leader or central control. It combines the inherited instructions and rules into complex processes ...

  13. Methodology for the specification of communication activities within the framework of a multi-layered architecture: Toward the definition of a knowledge base

    Science.gov (United States)

    Amyay, Omar

    A method defined in terms of synthesis and verification steps is presented. The specification of the services and protocols of communication within a multilayered architecture of the Open Systems Interconnection (OSI) type is an essential issue for the design of computer networks. The aim is to obtain an operational specification of the protocol service couple of a given layer. Planning synthesis and verification steps constitute a specification trajectory. The latter is based on the progressive integration of the 'initial data' constraints and verification of the specification originating from each synthesis step, through validity constraints that characterize an admissible solution. Two types of trajectories are proposed according to the style of the initial specification of the service protocol couple: operational type and service supplier viewpoint; knowledge property oriented type and service viewpoint. Synthesis and verification activities were developed and formalized in terms of labeled transition systems, temporal logic and epistemic logic. The originality of the second specification trajectory and the use of the epistemic logic are shown. An 'artificial intelligence' approach enables a conceptual model to be defined for a knowledge base system for implementing the method proposed. It is structured in three levels of representation of the knowledge relating to the domain, the reasoning characterizing synthesis and verification activities and the planning of the steps of a specification trajectory.

  14. Software Architecture: Architecture Constraints

    OpenAIRE

    Tibermacine, Chouki

    2014-01-01

    International audience In this chapter, we introduce an additional, yet essential, concept in describing software architectures : architecture constraints. We explain the precise role of these entities and their importance in object-oriented, component-based or service-oriented software engi-neering. We then describe the way in which they are specified and interpreted. An architect can define architecture constraints and then associate them to architectural descriptions to limit their stru...

  15. A distributed agent architecture for real-time knowledge-based systems: Real-time expert systems project, phase 1

    Science.gov (United States)

    Lee, S. Daniel

    1990-01-01

    We propose a distributed agent architecture (DAA) that can support a variety of paradigms based on both traditional real-time computing and artificial intelligence. DAA consists of distributed agents that are classified into two categories: reactive and cognitive. Reactive agents can be implemented directly in Ada to meet hard real-time requirements and be deployed on on-board embedded processors. A traditional real-time computing methodology under consideration is the rate monotonic theory that can guarantee schedulability based on analytical methods. AI techniques under consideration for reactive agents are approximate or anytime reasoning that can be implemented using Bayesian belief networks as in Guardian. Cognitive agents are traditional expert systems that can be implemented in ART-Ada to meet soft real-time requirements. During the initial design of cognitive agents, it is critical to consider the migration path that would allow initial deployment on ground-based workstations with eventual deployment on on-board processors. ART-Ada technology enables this migration while Lisp-based technologies make it difficult if not impossible. In addition to reactive and cognitive agents, a meta-level agent would be needed to coordinate multiple agents and to provide meta-level control.

  16. Architecture on Architecture

    DEFF Research Database (Denmark)

    Olesen, Karen

    2016-01-01

    how recognising the autonomy of architecture, not as an esoteric concept but as a valid source of information in a pragmatic design practice, may help us overcome the often-proclaimed dichotomy between formal autonomy and a societally committed architecture. It follows that in architectural education...

  17. The Truth Before and After: Brain Potentials Reveal Automatic Activation of Event Knowledge during Sentence Comprehension.

    Science.gov (United States)

    Nieuwland, Mante S

    2015-11-01

    How does knowledge of real-world events shape our understanding of incoming language? Do temporal terms like "before" and "after" impact the online recruitment of real-world event knowledge? These questions were addressed in two ERP experiments, wherein participants read sentences that started with "before" or "after" and contained a critical word that rendered each sentence true or false (e.g., "Before/After the global economic crisis, securing a mortgage was easy/harder"). The critical words were matched on predictability, rated truth value, and semantic relatedness to the words in the sentence. Regardless of whether participants explicitly verified the sentences or not, false-after-sentences elicited larger N400s than true-after-sentences, consistent with the well-established finding that semantic retrieval of concepts is facilitated when they are consistent with real-world knowledge. However, although the truth judgments did not differ between before- and after-sentences, no such sentence N400 truth value effect occurred in before-sentences, whereas false-before-sentences elicited an enhanced subsequent positive ERPs. The temporal term "before" itself elicited more negative ERPs at central electrode channels than "after." These patterns of results show that, irrespective of ultimate sentence truth value judgments, semantic retrieval of concepts is momentarily facilitated when they are consistent with the known event outcome compared to when they are not. However, this inappropriate facilitation incurs later processing costs as reflected in the subsequent positive ERP deflections. The results suggest that automatic activation of event knowledge can impede the incremental semantic processes required to establish sentence truth value. PMID:26244719

  18. The Three-Dimensional Architecture of the Internal Capsule of the Human Brain Demonstrated by Fiber Dissection Technique

    Directory of Open Access Journals (Sweden)

    Cristina Goga

    2015-01-01

    Full Text Available The fiber dissection technique involves peeling away white matter fiber tracts of the brain to display its three-dimensional anatomic arrangement. The intricate three-dimensional configuration and structure of the internal capsule (IC is not well defined. By using the fiber dissection technique, our aim was to expose and study the IC to achieve a clearer conception of its configuration and relationships with neighboring white matter fibers and central nuclei. The lateral and medial aspects of the temporal lobes of twenty, previously frozen, formalin-fixed human brains were dissected under the operating microscope using the fiber dissection technique.

  19. Review of the current knowledge of brain-/mind-based learning to present the optimum climate for, and the guided experience approach to teaching

    OpenAIRE

    Ronald Jean Degen

    2011-01-01

    The purpose of this paper is to review the current knowledge on brain-/mind-based learning, by drawing on the recent advances in cognitive science (particularly neuroscience) that have changed traditional education practices. The findings and theories that have influenced current understanding of learning are reviewed, without inclusion of the detailed descriptions of anatomical functioning of the human brain on with they are based (these descriptions can be found in the reference material). ...

  20. Application of fractal and grey level co-occurrence matrix analysis in evaluation of brain corpus callosum and cingulum architecture.

    Science.gov (United States)

    Pantic, Igor; Dacic, Sanja; Brkic, Predrag; Lavrnja, Irena; Pantic, Senka; Jovanovic, Tomislav; Pekovic, Sanja

    2014-10-01

    This aim of this study was to assess the discriminatory value of fractal and grey level co-occurrence matrix (GLCM) analysis methods in standard microscopy analysis of two histologically similar brain white mass regions that have different nerve fiber orientation. A total of 160 digital micrographs of thionine-stained rat brain white mass were acquired using a Pro-MicroScan DEM-200 instrument. Eighty micrographs from the anterior corpus callosum and eighty from the anterior cingulum areas of the brain were analyzed. The micrographs were evaluated using the National Institutes of Health ImageJ software and its plugins. For each micrograph, seven parameters were calculated: angular second moment, inverse difference moment, GLCM contrast, GLCM correlation, GLCM variance, fractal dimension, and lacunarity. Using the Receiver operating characteristic analysis, the highest discriminatory value was determined for inverse difference moment (IDM) (area under the receiver operating characteristic (ROC) curve equaled 0.925, and for the criterion IDM≤0.610 the sensitivity and specificity were 82.5 and 87.5%, respectively). Most of the other parameters also showed good sensitivity and specificity. The results indicate that GLCM and fractal analysis methods, when applied together in brain histology analysis, are highly capable of discriminating white mass structures that have different axonal orientation. PMID:24967845

  1. Knowledge of Mild Traumatic Brain Injury: Effects of age, locality, occupation, media and sports participation

    Directory of Open Access Journals (Sweden)

    2015-09-01

    Results: Misconceptions about TBI were reported by participants, irrespective of gender, locality, occupation, or history of sports participation. There were no significant differences in knowledge scores across these demographic groups. In particular, healthcare and education workers did not score any higher than other occupations. At least 40% of respondents answered either incorrectly or “I don’t know” on items related to gender differences, the utility of neuroimaging, and patient insight into their impairments. For those in non-medical, professional occupations, the older they were the less they knew about TBI (r = -.299, p = 0.009. In contrast, a positive correlation (r = 0.268, p = 0.018 was found between age and TBI knowledge for workers in healthcare or education. Conclusions: Misconceptions about TBI are present in Australia and are consistent across genders, localities, occupations and sport participation groups. A concern is that risk for misconceptions is not lower in healthcare or education professions. This suggests that professional development for groups most likely to be the frontline referral resources and supports for head injured children and adults may require further training.

  2. A building characterization-based method for the advancement of knowledge on external architectural features of traditional rural buildings

    Directory of Open Access Journals (Sweden)

    Porto, S. M. C.

    2013-12-01

    Full Text Available The significant role that traditional rural buildings have with regard to environmental conservation and rural development is widely acknowledged by the scientific community. These buildings must be protected from inappropriate building interventions that may stem from their rather superficial knowledge. Therefore, this study was directed towards overcoming such a limitation by developing a method based on traditional rural buildings’ characterization. In particular, the study aimed at the characterization of building materials and techniques used for the construction of a number of building components that make up the external envelope of traditional rural buildings. The application of the method to a homogeneous area of the Etna Regional Park (Italy highlighted the need to improve the technical norms of the park’s Territorial Coordination Plan to respect the building characteristics of the traditional rural buildings located in the protected area.La comunidad científica le atribuye a las construcciones rurales tradicionales un papel fundamental en términos de conservación del medioambiente y de evolución rural. Dichos edificios deben ser protegidos contra obras inapropiadas debidas a un conocimiento más bien superficial. Por lo tanto, el objetivo de este estudio fue el de eliminar dichas limitaciones desarrollando un método basado en la caracterización de las construcciones rurales tradicionales, que puede ser aplicado para mejorar el conocimiento de estas últimas. En particular, el susodicho estudio tiene la finalidad de caracterizar los materiales y las técnicas constructivas a emplear para la construcción de algunos componentes del envoltorio externo de las construcciones rurales tradicionales. La aplicación del método propuesto a una zona homogénea del Parque Regional del Etna (Italia puso de relieve la necesidad de mejorar las normas técnicas del Plan de Coordinación Territorial del parque para respetar las caracter

  3. Experiential and Doctrinal Religious Knowledge Categorization in Parkinson's Disease: Behavioral and Brain Correlates.

    Science.gov (United States)

    Modestino, Edward J; O'Toole, Partrick; Reinhofer, AnnaMarie

    2016-01-01

    Recent studies suggest changes in religious cognition in a subgroup of patients with Parkinson's disease (PD e.g., Butler et al., 2011). It is unclear whether this deficit extends to both doctrinal and experiential categorization forms of religious cognition. Kapogiannis et al. (2009b) dissociated experiential and doctrinal religious knowledge to different neural networks using fMRI. We examined Kapogiannis' dissociation against the background of PD side of onset (LOPD, ROPD), assessing performance both On- and Off-medication. In the behavioral portion of the study, we used a statement classification task in combination with scholar derived test sets for experiential and doctrinal religious knowledge categorization in conjunction with neuropsychological measures. In the neuroimaging portion of the study, we expanded on Kapogiannis' study by examining the same networks in PD. The behavioral data revealed that all groups rated (categorized) the scholar derived tests of experiential and doctrinal significantly differently than the scholars. All groups, including the scholars, classified more phrases as doctrinal than experiential. Religious cognition differed in the PD groups: those with PD Off-medication and LOPD Off-medication comprehended scholar defined experiential phrases with more difficulty, making them more likely to be classified as mixed or doctrinal. This was in contrast to the subjective frequency of classification of phrases as experiential paired with a cognitive decline in PD Off-medication; whereas PD On-medication showed a positive correlation with cognitive state and subjective doctrinal classification. For ROPD, cognitive state was associated with subjective experiential and doctrinal frequency of classification. With more intact intellect, there was a greater likelihood of classifying phrases subjectively as mixed, and the converse for experiential. Furthermore, religiosity negatively predicted subjective doctrinal frequency in LOPD, with the

  4. Teaching About “Brain and Learning” in High School Biology Classes: Effects on Teachers' Knowledge and Students' Theory of Intelligence

    Science.gov (United States)

    Dekker, Sanne; Jolles, Jelle

    2015-01-01

    This study evaluated a new teaching module about “Brain and Learning” using a controlled design. The module was implemented in high school biology classes and comprised three lessons: (1) brain processes underlying learning; (2) neuropsychological development during adolescence; and (3) lifestyle factors that influence learning performance. Participants were 32 biology teachers who were interested in “Brain and Learning” and 1241 students in grades 8–9. Teachers' knowledge and students' beliefs about learning potential were examined using online questionnaires. Results indicated that before intervention, biology teachers were significantly less familiar with how the brain functions and develops than with its structure and with basic neuroscientific concepts (46 vs. 75% correct answers). After intervention, teachers' knowledge of “Brain and Learning” had significantly increased (64%), and more students believed that intelligence is malleable (incremental theory). This emphasizes the potential value of a short teaching module, both for improving biology teachers' insights into “Brain and Learning,” and for changing students' beliefs about intelligence. PMID:26648900

  5. A multidisciplinary approach to understanding developmental dyslexia within working-memory architecture: genotypes, phenotypes, brain, and instruction.

    Science.gov (United States)

    Berninger, Virginia W; Raskind, Wendy; Richards, Todd; Abbott, Robert; Stock, Pat

    2008-01-01

    A unifying theoretical framework of three working memory components provides a systems perspective for discussing past and new findings in a 12-year research program that point to heterogeneity in the genetic and brain basis and behavioral expression of dyslexia: (a) codes for word-form storage and processing, (b) time-sensitive phonological and orthographic loops for maintaining information in working memory or outputting it, and (c) executive functions for language (e.g., rapid automatic switching of attention). Results, which span the genetic to neurological to behavioral levels of analysis, point to possible impairment in any one or combination of these working memory components in individuals with dyslexia. A DNA variation on chromosome 15 may be linked with the phonological word-form in the first working-memory component. A DNA variation on chromosome 6 may be linked with slow rapid automatic switching, inattention ratings, and impaired goal-directed activity ratings in the third working-memory component. Brain and behavioral findings support (a) Triple Word Form Theory: phonological, orthographic, and morphological word-forms and their parts contribute to learning to read and spell words; and (b) Cross-Word Form Mapping: in the process of learning to read and spell words children compute the inter-relationships among the three word-forms and their parts. However, children with dyslexia may require more focus on the morphological word-form and its parts and their relationships with the other two word-forms and their parts than do normal readers. Also, children with dyslexia have unusual difficulties in sustaining phonological loop function in working memory over time; their impaired orthographic loop function may interfere with learning to write alphabet letters and spell, which may be as impaired as word decoding and reading. Impaired executive functions may interfere with the efficiency of working memory in processing oral and written language. PMID

  6. ARCHITECTURE IN THE ISLAMIC CIVILIZATION: MUSLIM BUILDING OR ISLAMIC ARCHITECTURE

    Directory of Open Access Journals (Sweden)

    Ayat Ali Yassin

    2012-12-01

    Full Text Available The main problem of the theory in the arena of islamic architecture is affected by some of its Westernthoughts, and stereotyping the islamic architecture according to Western thoughts; this leads to the breakdownof the foundations in the islamic architecture. It is a myth that islamic architecture is subjected to theinfluence from foreign architectures. This paper will highlight the dialectical concept of islamic architecture ormuslim buildings and the areas of recognition in islamic architecture. It will also widen the knowledge in thecharacteristics of each point in time according to the stages of islamic architecture from the prophetic agemoving through the architecture outside the city of Medina, the Caliphs, the Umayyad, Abbasid, andarchitectural models by spatial and time periods, taking Iraq as the example to explain how the Islam influentson architecture and vice versa.

  7. Artificial cognition architectures

    CERN Document Server

    Crowder, James A; Friess, Shelli A

    2013-01-01

    The goal of this book is to establish the foundation, principles, theory, and concepts that are the backbone of real, autonomous Artificial Intelligence. Presented here are some basic human intelligence concepts framed for Artificial Intelligence systems. These include concepts like Metacognition and Metamemory, along with architectural constructs for Artificial Intelligence versions of human brain functions like the prefrontal cortex. Also presented are possible hardware and software architectures that lend themselves to learning, reasoning, and self-evolution

  8. Temporal evolution of brain reorganization under cross-modal training: insights into the functional architecture of encoding and retrieval networks

    Science.gov (United States)

    Likova, Lora T.

    2015-03-01

    This study is based on the recent discovery of massive and well-structured cross-modal memory activation generated in the primary visual cortex (V1) of totally blind people as a result of novel training in drawing without any vision (Likova, 2012). This unexpected functional reorganization of primary visual cortex was obtained after undergoing only a week of training by the novel Cognitive-Kinesthetic Method, and was consistent across pilot groups of different categories of visual deprivation: congenitally blind, late-onset blind and blindfolded (Likova, 2014). These findings led us to implicate V1 as the implementation of the theoretical visuo-spatial 'sketchpad' for working memory in the human brain. Since neither the source nor the subsequent 'recipient' of this non-visual memory information in V1 is known, these results raise a number of important questions about the underlying functional organization of the respective encoding and retrieval networks in the brain. To address these questions, an individual totally blind from birth was given a week of Cognitive-Kinesthetic training, accompanied by functional magnetic resonance imaging (fMRI) both before and just after training, and again after a two-month consolidation period. The results revealed a remarkable temporal sequence of training-based response reorganization in both the hippocampal complex and the temporal-lobe object processing hierarchy over the prolonged consolidation period. In particular, a pattern of profound learning-based transformations in the hippocampus was strongly reflected in V1, with the retrieval function showing massive growth as result of the Cognitive-Kinesthetic memory training and consolidation, while the initially strong hippocampal response during tactile exploration and encoding became non-existent. Furthermore, after training, an alternating patch structure in the form of a cascade of discrete ventral regions underwent radical transformations to reach complete functional

  9. Software architecture as a set of architectural design decisions

    NARCIS (Netherlands)

    Jansen, Anton; Bosch, Jan; Nord, R; Medvidovic, N; Krikhaar, R; Khrhaar, R; Stafford, J; Bosch, J

    2006-01-01

    Software architectures have high costs for change, are complex, and erode during evolution. We believe these problems are partially due to knowledge vaporization. Currently, almost all the knowledge and information about the design decisions the architecture is based on are implicitly embedded in th

  10. Brain architecture of the largest living land arthropod, the Giant Robber Crab Birgus latro (Crustacea, Anomura, Coenobitidae: evidence for a prominent central olfactory pathway?

    Directory of Open Access Journals (Sweden)

    Krieger Jakob

    2010-09-01

    Full Text Available Abstract Background Several lineages within the Crustacea conquered land independently during evolution, thereby requiring physiological adaptations for a semi-terrestrial or even a fully terrestrial lifestyle. Birgus latro Linnaeus, 1767, the giant robber crab or coconut crab (Anomura, Coenobitidae, is the largest land-living arthropod and inhabits Indo-Pacific islands such as Christmas Island. B. latro has served as a model in numerous studies of physiological aspects related to the conquest of land by crustaceans. From an olfactory point of view, a transition from sea to land means that molecules need to be detected in gas phase instead of in water solution. Previous studies have provided physiological evidence that terrestrial hermit crabs (Coenobitidae such as B. latro have a sensitive and well differentiated sense of smell. Here we analyze the brain, in particular the olfactory processing areas of B. latro, by morphological analysis followed by 3 D reconstruction and immunocytochemical studies of synaptic proteins and a neuropeptide. Results The primary and secondary olfactory centers dominate the brain of B. latro and together account for ca. 40% of the neuropil volume in its brain. The paired olfactory neuropils are tripartite and composed of more than 1,000 columnar olfactory glomeruli, which are radially arranged around the periphery of the olfactory neuropils. The glomeruli are innervated ca. 90,000 local interneurons and ca. 160,000 projection neurons per side. The secondary olfactory centers, the paired hemiellipsoid neuropils, are targeted by the axons of these olfactory projection neurons. The projection neuron axonal branches make contact to ca. 250.000 interneurons (per side associated with the hemiellipsoid neuropils. The hemiellipsoid body neuropil is organized into parallel neuropil lamellae, a design that is quite unusual for decapod crustaceans. The architecture of the optic neuropils and areas associated with antenna two

  11. Invasive brain-machine interfaces: a survey of paralyzed patients’ attitudes, knowledge and methods of information retrieval

    Science.gov (United States)

    Lahr, Jacob; Schwartz, Christina; Heimbach, Bernhard; Aertsen, Ad; Rickert, Jörn; Ball, Tonio

    2015-08-01

    Objective. Brain-machine interfaces (BMI) are an emerging therapeutic option that can allow paralyzed patients to gain control over assistive technology devices (ATDs). BMI approaches can be broadly classified into invasive (based on intracranially implanted electrodes) and noninvasive (based on skin electrodes or extracorporeal sensors). Invasive BMIs have a favorable signal-to-noise ratio, and thus allow for the extraction of more information than noninvasive BMIs, but they are also associated with the risks related to neurosurgical device implantation. Current noninvasive BMI approaches are typically concerned, among other issues, with long setup times and/or intensive training. Recent studies have investigated the attitudes of paralyzed patients eligible for BMIs, particularly patients affected by amyotrophic lateral sclerosis (ALS). These studies indicate that paralyzed patients are indeed interested in BMIs. Little is known, however, about the degree of knowledge among paralyzed patients concerning BMI approaches or about how patients retrieve information on ATDs. Furthermore, it is not yet clear if paralyzed patients would accept intracranial implantation of BMI electrodes with the premise of decoding improvements, and what the attitudes of a broader range of patients with diseases such as stroke or spinal cord injury are towards this new kind of treatment. Approach. Using a questionnaire, we surveyed 131 paralyzed patients for their opinions on invasive BMIs and their attitude toward invasive BMI treatment options. Main results. The majority of the patients knew about and had a positive attitude toward invasive BMI approaches. The group of ALS patients was especially open to the concept of BMIs. The acceptance of invasive BMI technology depended on the improvements expected from the technology. Furthermore, the survey revealed that for paralyzed patients, the Internet is an important source of information on ATDs. Significance. Websites tailored to

  12. Economics-driven software architecture

    CERN Document Server

    Mistrik, Ivan; Kazman, Rick; Zhang, Yuanyuan

    2014-01-01

    Economics-driven Software Architecture presents a guide for engineers and architects who need to understand the economic impact of architecture design decisions: the long term and strategic viability, cost-effectiveness, and sustainability of applications and systems. Economics-driven software development can increase quality, productivity, and profitability, but comprehensive knowledge is needed to understand the architectural challenges involved in dealing with the development of large, architecturally challenging systems in an economic way. This book covers how to apply economic consider

  13. Architecture in the network society

    DEFF Research Database (Denmark)

    2004-01-01

    Under the theme Architecture in the Network Society, participants were invited to focus on the dialog and sharing of knowledge between architects and other disciplines and to reflect on, and propose, new methods in the design process, to enhance and improve the impact of information technology...... on architecture. This conference and the past history of eCAADe is an example on establishing a social network for the sharing of knowledge regarding the use of computers in architectural education and research....

  14. Brain-mind dyad, human experience, the consciousness tetrad and lattice of mental operations: And further, The need to integrate knowledge from diverse disciplines

    Directory of Open Access Journals (Sweden)

    Ajai R Singh

    2011-03-01

    Full Text Available Brain, Mind and Consciousness are the research concerns of psychiatrists, psychologists, neurologists, cognitive neuroscientists and philosophers. All of them are working in different and important ways to understand the workings of the brain, the mysteries of the mind and to grasp that elusive concept called consciousness. Although they are all justified in forwarding their respective researches, it is also necessary to integrate these diverse appearing understandings and try and get a comprehensive perspective that is, hopefully, more than the sum of their parts. There is also the need to understand what each one is doing, and by the other, to understand each other's basic and fundamental ideological and foundational underpinnings. This must be followed by a comprehensive and critical dialogue between the respective disciplines. Moreover, the concept of mind and consciousness in Indian thought needs careful delineation and critical/evidential enquiry to make it internationally relevant. The brain-mind dyad must be understood, with brain as the structural correlate of the mind, and mind as the functional correlate of the brain. To understand human experience, we need a triad of external environment, internal environment and a consciousness that makes sense of both. We need to evolve a consensus on the definition of consciousness, for which a working definition in the form of a Consciousness Tetrad of Default, Aware, Operational and Evolved Consciousness is presented. It is equally necessary to understand the connection between physical changes in the brain and mental operations, and thereby untangle and comprehend the lattice of mental operations. Interdisciplinary work and knowledge sharing, in an atmosphere of healthy give and take of ideas, and with a view to understand the significance of each other's work, and also to critically evaluate the present corpus of knowledge from these diverse appearing fields, and then carry forward from there

  15. Brain-Mind Dyad, Human Experience, the Consciousness Tetrad and Lattice of Mental Operations: And Further, The Need to Integrate Knowledge from Diverse Disciplines

    Science.gov (United States)

    Singh, Ajai R.; Singh, Shakuntala A.

    2011-01-01

    Brain, Mind and Consciousness are the research concerns of psychiatrists, psychologists, neurologists, cognitive neuroscientists and philosophers. All of them are working in different and important ways to understand the workings of the brain, the mysteries of the mind and to grasp that elusive concept called consciousness. Although they are all justified in forwarding their respective researches, it is also necessary to integrate these diverse appearing understandings and try and get a comprehensive perspective that is, hopefully, more than the sum of their parts. There is also the need to understand what each one is doing, and by the other, to understand each other’s basic and fundamental ideological and foundational underpinnings. This must be followed by a comprehensive and critical dialogue between the respective disciplines. Moreover, the concept of mind and consciousness in Indian thought needs careful delineation and critical/evidential enquiry to make it internationally relevant. The brain-mind dyad must be understood, with brain as the structural correlate of the mind, and mind as the functional correlate of the brain. To understand human experience, we need a triad of external environment, internal environment and a consciousness that makes sense of both. We need to evolve a consensus on the definition of consciousness, for which a working definition in the form of a Consciousness Tetrad of Default, Aware, Operational and Evolved Consciousness is presented. It is equally necessary to understand the connection between physical changes in the brain and mental operations, and thereby untangle and comprehend the lattice of mental operations. Interdisciplinary work and knowledge sharing, in an atmosphere of healthy give and take of ideas, and with a view to understand the significance of each other’s work, and also to critically evaluate the present corpus of knowledge from these diverse appearing fields, and then carry forward from there in a spirit of

  16. Individual 3D region-of-interest atlas of the human brain: knowledge-based class image analysis for extraction of anatomical objects

    Science.gov (United States)

    Wagenknecht, Gudrun; Kaiser, Hans-Juergen; Sabri, Osama; Buell, Udalrich

    2000-06-01

    After neural network-based classification of tissue types, the second step of atlas extraction is knowledge-based class image analysis to get anatomically meaningful objects. Basic algorithms are region growing, mathematical morphology operations, and template matching. A special algorithm was designed for each object. The class label of each voxel and the knowledge about the relative position of anatomical objects to each other and to the sagittal midplane of the brain can be utilized for object extraction. User interaction is only necessary to define starting, mid- and end planes for most object extractions and to determine the number of iterations for erosion and dilation operations. Extraction can be done for the following anatomical brain regions: cerebrum; cerebral hemispheres; cerebellum; brain stem; white matter (e.g., centrum semiovale); gray matter [cortex, frontal, parietal, occipital, temporal lobes, cingulum, insula, basal ganglia (nuclei caudati, putamen, thalami)]. For atlas- based quantification of functional data, anatomical objects can be convoluted with the point spread function of functional data to take into account the different resolutions of morphological and functional modalities. This method allows individual atlas extraction from MRI image data of a patient without the need of warping individual data to an anatomical or statistical MRI brain atlas.

  17. Architectural Slicing

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2013-01-01

    Architectural prototyping is a widely used practice, con- cerned with taking architectural decisions through experiments with light- weight implementations. However, many architectural decisions are only taken when systems are already (partially) implemented. This is prob- lematic in the context of...... architectural prototyping since experiments with full systems are complex and expensive and thus architectural learn- ing is hindered. In this paper, we propose a novel technique for harvest- ing architectural prototypes from existing systems, \\architectural slic- ing", based on dynamic program slicing. Given a...... system and a slicing criterion, architectural slicing produces an architectural prototype that contain the elements in the architecture that are dependent on the ele- ments in the slicing criterion. Furthermore, we present an initial design and implementation of an architectural slicer for Java....

  18. Architectural Prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders......' concerns with respect to a system under development. An architectural prototype is primarily a learning and communication vehicle used to explore and experiment with alternative architectural styles, features, and patterns in order to balance different architectural qualities. The use of architectural...... prototypes in the development process is discussed, and we argue that such prototypes can play a role throughout the entire process. The use of architectural prototypes is illustrated by three distinct cases of creating software systems. We argue that architectural prototyping can provide key insights that...

  19. Architectural prototyping

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2004-01-01

    A major part of software architecture design is learning how specific architectural designs balance the concerns of stakeholders. We explore the notion of "architectural prototypes", correspondingly architectural prototyping, as a means of using executable prototypes to investigate stakeholders......' concerns with respect to a system under development. An architectural prototype is primarily a learning and communication vehicle used to explore and experiment with alternative architectural styles, features, and patterns in order to balance different architectural qualities. The use of architectural...... prototypes in the development process is discussed, and we argue that such prototypes can play a role throughout the entire process. The use of architectural prototypes is illustrated by three distinct cases of creating software systems. We argue that architectural prototyping can provide key insights that...

  20. Essential software architecture

    CERN Document Server

    Gorton, Ian

    2011-01-01

    Job titles like ""Technical Architect"" and ""Chief Architect"" nowadays abound in software industry, yet many people suspect that ""architecture"" is one of the most overused and least understood terms in professional software development. Gorton's book tries to resolve this dilemma. It concisely describes the essential elements of knowledge and key skills required to be a software architect. The explanations encompass the essentials of architecture thinking, practices, and supporting technologies. They range from a general understanding of structure and quality attributes through technical i

  1. RECONSTRUCTING DECONSTRUCTION IN ARCHITECTURE

    Directory of Open Access Journals (Sweden)

    IDHAM Noor Cholis

    2013-01-01

    Full Text Available This paper examines deconstruction in architecture and forms used, which triggered by dispute of form and its scientification claimed by deconstructivists. Deconstruction terminologyis studied in the first part related to architecture field as a base knowledge. Some sample works of known deconstructionist architects are assessed in order to understand how their building is deconstructed and what forms they used. Discussion about form and its relation to other fields is then pursued by discussing the involvement of terminology of science, aesthetic pattern, and human life. The results of this discussion give clear understanding how form related to deconstruction in architecture are used.

  2. Solid knowledge

    DEFF Research Database (Denmark)

    Brix, Anders

    2008-01-01

    The great icons of industrial and architectural design are cornerstones of our material culture. They are referred to again and again in education, research and cultural debate, and as such they have become nodal points of human discourse. The knowledge embedded in such artefacts has often been...... referred to as ‘silent knowledge’....

  3. Software synthesis using generic architectures

    Science.gov (United States)

    Bhansali, Sanjay

    1993-01-01

    A framework for synthesizing software systems based on abstracting software system designs and the design process is described. The result of such an abstraction process is a generic architecture and the process knowledge for customizing the architecture. The customization process knowledge is used to assist a designer in customizing the architecture as opposed to completely automating the design of systems. Our approach using an implemented example of a generic tracking architecture which was customized in two different domains is illustrated. How the designs produced using KASE compare to the original designs of the two systems, and current work and plans for extending KASE to other application areas are described.

  4. Dyslexia: An Altered Brain Architecture

    Directory of Open Access Journals (Sweden)

    Felice Corona

    2012-01-01

    Full Text Available Problem statement: Dyslexia is defined as a syndrome belonging to Specific Learning Disorders, DSA code F81.0. Its most visible manifestation is the difficulty that subjects have to correctly read out loud and quickly. These impediments are not due to lack of linguistic intellectual abilities, not education, or properly to external causes sensory deficits. Approach: The objective was oriented in the verification, in the construction and examination of courses and projects likely to involve the recognition and social relationships, education of dyslexic children in relation to which still struggles to make a path of inclusion, integration and full acceptance in any context and priority in school. Results: Following a Memorandum of Understanding between the Ministry of Education, the Foundation Telecom Italy and the Italian Dyslexia signed in Italy, has been pursued for the purpose of promoting research-action on the DSA from the local school. Conclusion: The main parameters that we propose pay attention to cognitive factors, emotional and relational processes that underlie learning designed.

  5. Special Education Teachers' Knowledge and Use of Brain-Based Teaching, Common Core State Standards, Formative Feedback Practices and Instructional Efficacy for the Diverse Learning Needs of Students in High and Low Proficiency Groups

    Science.gov (United States)

    Walker-Thompson, Malasia

    2014-01-01

    This study examined special education teachers' knowledge and use of: brain-based teaching strategies, Common Core State Standards, formative feedback, and instructional efficacy for diverse students. The study identified the differences amongst special education teachers' responses on the dimensions of brain-based teaching strategies, Common Core…

  6. Digitally-Driven Architecture

    Directory of Open Access Journals (Sweden)

    Henriette Bier

    2010-06-01

    Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisa­tion focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means. In this context, this sixth Footprint issue examines the influence of digital means as prag­matic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

  7. Digitally-Driven Architecture

    Directory of Open Access Journals (Sweden)

    Henriette Bier

    2014-07-01

    Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisation focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means.In this context, this sixth Footprint issue examines the influence of digital means as pragmatic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

  8. Architectural Contestation

    OpenAIRE

    Merle, J.

    2012-01-01

    This dissertation addresses the reductive reading of Georges Bataille's work done within the field of architectural criticism and theory which tends to set aside the fundamental ‘broken’ totality of Bataille's oeuvre and also to narrowly interpret it as a mere critique of architectural form, consequently presenting it either as the negation of all form of architecture or as the critique of 'classical' architectural forms. Against this ‘appropriation’, i.e. this reductive reading and the subse...

  9. Architectural Theatricality

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen; Fisker, Anna Marie; Kirkegaard, Poul Henning

    2013-01-01

    and recovery through the architecture framing eating experiences, this article examines, from a theoretical perspective, two less debated concepts relating to hospitality called food design and architectural theatricality. In architectural theory the nineteenth century German architect Gottfried...... Semper is known for his writings on theatricality, understood as a holistic design approach emphasizing the contextual, cultural, ritual and social meanings rooted in architecture. Relative hereto, the International Food Design Society recently argued, in a similar holistic manner, that the methodology...

  10. VLSI architecture

    Energy Technology Data Exchange (ETDEWEB)

    Randell, B.; Treleaven, P.C.

    1983-01-01

    This book is a collection of course papers which discusses the latest (1982) milestone of electronic building blocks and its effect on computer architecture. Contributions range from selecting a VLSI process technology to Japan's Fifth Generation Computer Architecture. Contents, abridged: VLSI and machine architecture. Graphic design aids: HED and FATFREDDY. On the LUCIFER system. Clocking of VLSI circuits. Decentralised computer architectures for VLSI. Index.

  11. Architecture & Environment

    Science.gov (United States)

    Erickson, Mary; Delahunt, Michael

    2010-01-01

    Most art teachers would agree that architecture is an important form of visual art, but they do not always include it in their curriculums. In this article, the authors share core ideas from "Architecture and Environment," a teaching resource that they developed out of a long-term interest in teaching architecture and their fascination with the…

  12. How Many Brains Does It Take to Build a New Light: Knowledge Management Challenges of a Transdisciplinary Project

    Science.gov (United States)

    della Chiesa, Bruno; Christoph, Vanessa; Hinton, Christina

    2009-01-01

    The Organization for Economic Cooperation and Development's (OECD) Center for Educational Research and Innovation (CERI) carried out the "Learning Sciences and Brain Research" project (1999-2007) to investigate how neuroscience research can inform education policy and practice. This transdisciplinary project brought many challenges. Within the…

  13. Federation Agreements - Observations, Considerations and Proposals out of the NATO MSG-052 Working Group - Knowledge Network for Federation Architecture and Design

    NARCIS (Netherlands)

    Huiskamp, W.; Loper, M.; Cutts, D.E.

    2007-01-01

    Designing and managing distributed simulation systems is a complex process requiring extensive experience, in-depth knowledge, and unique skills to construct a federation which meets a myriad of operational, functional and technical requirements. Unfortunately, the practical knowledge gained in the

  14. Design theory versus architectural design

    OpenAIRE

    W R Spillers

    1986-01-01

    This paper is an attempt to track the path of architectural design both on design-theoretical and on practical (computer-aided design) planes. It begins with the practical problems of design which can be couched in terms of mathematical programming problems. The potential for applications of artificial intelligence and knowledge-based systems in architectural design is then considered. Last the place of architectural design within design theory is discussed.

  15. Architectural Prototyping in Industrial Practice

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2008-01-01

    Architectural prototyping is the process of using executable code to investigate stakeholders’ software architecture concerns with respect to a system under development. Previous work has established this as a useful and cost-effective way of exploration and learning of the design space of a system......, in addressing issues regarding quality attributes, in addressing architectural risks, and in addressing the problem of knowledge transfer and conformance. Little work has been reported so far on the actual industrial use of architectural prototyping. In this paper, we report from an ethnographical...... study and focus group involving architects from four companies in which we have focused on architectural prototypes. Our findings conclude that architectural prototypes play an important role in resolving problems experimentally, but less so in exploring alternative solutions. Furthermore, architectural...

  16. Architecture and Energy

    DEFF Research Database (Denmark)

    Lauring, Michael; Marsh, Rob

    2009-01-01

    , and where the transition from an industrial to an information- or knowledge-based society is well-developed. The last three decades of the 20th century show many conscientious - both governmental and architectural - Danish attempts at creating buildings with lower heat consumption. The lower U...

  17. Architectural Engineering to Super-Light Structures

    DEFF Research Database (Denmark)

    Castberg, Niels Andreas

    concept still has a considerable unexploited potential. The thesis contributes with new knowledge on architectural engineering in a Danish context, and how it can positively influence the design process. Furthermore, new knowledge are presented via examples of how Super-Light Structures support...... with architectural engineering as a starting point. The thesis is based on a two stringed hypothesis: Architectural engineering gives rise to better architecture and Super-Light Structures support and enables a static, challenging architecture. The aim of the thesis is to clarify architectural...... engineering's impact on the work process between architects and engineers in the design development. Using architectural engineering, Super-Light Structures are examined in an architectural context, and it is explained how digital tools can support architectural engineering and design of Super...

  18. Architectural freedom and industrialised architecture

    DEFF Research Database (Denmark)

    Vestergaard, Inge

    2012-01-01

    Architectural freedom and industrialized architecture. Inge Vestergaard, Associate Professor, Cand. Arch. Aarhus School of Architecture, Denmark Noerreport 20, 8000 Aarhus C Telephone +45 89 36 0000 E-mai l inge.vestergaard@aarch.dk Based on the repetitive architecture from the "building boom" 1960...... to 1973 it is discussed how architects can handle these Danish element and montage buildings through the transformation to upgraded aesthetical, functional and energy efficient architecture. The method used is analysis of cases, parallels to literature studies and producer interviews. This analysis...... compares "best practice" in Denmark and "best practice" in Austria. The modern architects accepted the fact that industrialized architecture told the storey of repetition and monotonous as basic condition. This article aims to explain that architecture can be thought as a complex and diverse design through...

  19. Brain Basics

    Medline Plus

    Full Text Available ... the understanding of how the brain grows and works and the effects of genes and environment on mental health. This knowledge is allowing scientists to make important discoveries that ...

  20. NeuroArch: A Graph dB for Querying and Executing Fruit Fly Brain Circuits

    OpenAIRE

    Givon, Lev E.; Lazar, Aurel A; Ukani, Nikul H

    2015-01-01

    NeuroArch is a database for codifying knowledge about fruit fly brain circuits. It is designed with two user communities in mind: (i) neurobiologists interested in querying the database to address questions regarding neu- roanatomy, neural circuits, neurons, synapses, neurotransmitters, and gene expression, and (ii) computational neuroscientists interested in the instantiation of models of neural circuits and architectures, their program execution, and validation of hypotheses regarding brain...

  1. Architecture Sustainability

    OpenAIRE

    Avgeriou, Paris; Stal, Michael; Hilliard, Rich

    2013-01-01

    Software architecture is the foundation of software system development, encompassing a system's architects' and stakeholders' strategic decisions. A special issue of IEEE Software is intended to raise awareness of architecture sustainability issues and increase interest and work in the area. The first Web extra at http://youtu.be/wUGHvocfix0 is an audio interview in which Davide Falessi speaks with guest editors Paris Avgeriou and Rich Hilliard about the importance of architecture sustainabil...

  2. Catalyst Architecture

    DEFF Research Database (Denmark)

    Kiib, Hans; Marling, Gitte; Hansen, Peter Mandal

    2014-01-01

    How can architecture promote the enriching experiences of the tolerant, the democratic, and the learning city - a city worth living in, worth supporting and worth investing in? Catalyst Architecture comprises architectural projects, which, by virtue of their location, context and their combination...... of programs, have a role in mediating positive social and/or cultural development. In this sense, we talk about architecture as a catalyst for: sustainable adaptation of the city’s infrastructure appropriate renovation of dilapidated urban districts strengthening of social cohesiveness in the city...

  3. Systemic Architecture

    DEFF Research Database (Denmark)

    Poletto, Marco; Pasquero, Claudia

    2012-01-01

    This is a manual investigating the subject of urban ecology and systemic development from the perspective of architectural design. It sets out to explore two main goals: to discuss the contemporary relevance of a systemic practice to architectural design, and to share a toolbox of informational...... design protocols developed to describe the city as a territory of self-organization. Collecting together nearly a decade of design experiments by the authors and their practice, ecoLogicStudio, the book discusses key disciplinary definitions such as ecologic urbanism, algorithmic architecture, bottom......-up or tactical design, behavioural space and the boundary of the natural and the artificial realms within the city and architecture. A new kind of "real-time world-city" is illustrated in the form of an operational design manual for the assemblage of proto-architectures, the incubation of proto...

  4. Debate as Methodology to Learn Architectural Critics

    OpenAIRE

    Mileto, Camilla; Vegas López-Manzanares, Fernando; Cristini, Valentina; La Spina, Vincenzina; García Soriano, Lidia

    2012-01-01

    Proceedings of INTED2012 Conference. 5th-7th March 2012, Valencia, Spain. Among the capabilities distributed by knowledge areas belonging to the studies of Architecture, the capability of being able to express architectural critics is a specific one assigned completely to the Composition area, both by the Ministery and by the different curricula of the some thirty schools of architecture existing in Spain. Learning how to make an architectural critic is a complex process based ...

  5. Software Architecture Design Reasoning

    Science.gov (United States)

    Tang, Antony; van Vliet, Hans

    Despite recent advancements in software architecture knowledge management and design rationale modeling, industrial practice is behind in adopting these methods. The lack of empirical proofs and the lack of a practical process that can be easily incorporated by practitioners are some of the hindrance for adoptions. In particular, the process to support systematic design reasoning is not available. To rectify this issue, we propose a design reasoning process to help architects cope with an architectural design environment where design concerns are cross-cutting and diversified.We use an industrial case study to validate that the design reasoning process can help improve the quality of software architecture design. The results have indicated that associating design concerns and identifying design options are important steps in design reasoning.

  6. Humanizing Architecture

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    2015-01-01

    The article proposes the urban digital gallery as an opportunity to explore the relationship between ‘human’ and ‘technology,’ through the programming of media architecture. It takes a curatorial perspective when proposing an ontological shift from considering media facades as visual spectacles to...... agency and a sense of being by way of dematerializing architecture. This is achieved by way of programming the symbolic to provide new emotional realizations and situations of enlightenment in the public audience. This reflects a greater potential to humanize the digital in media architecture....

  7. Architectural technology

    DEFF Research Database (Denmark)

    2005-01-01

    The booklet offers an overall introduction to the Institute of Architectural Technology and its projects and activities, and an invitation to the reader to contact the institute or the individual researcher for further information. The research, which takes place at the Institute of Architectural...... Technology at the Roayl Danish Academy of Fine Arts, School of Architecture, reflects a spread between strategic, goal-oriented pilot projects, commissioned by a ministry, a fund or a private company, and on the other hand projects which originate from strong personal interests and enthusiasm of individual...

  8. 3D Reconstructed Cyto-, Muscarinic M2 Receptor, and Fiber Architecture of the Rat Brain Registered to the Waxholm Space Atlas

    Science.gov (United States)

    Schubert, Nicole; Axer, Markus; Schober, Martin; Huynh, Anh-Minh; Huysegoms, Marcel; Palomero-Gallagher, Nicola; Bjaalie, Jan G.; Leergaard, Trygve B.; Kirlangic, Mehmet E.; Amunts, Katrin; Zilles, Karl

    2016-01-01

    High-resolution multiscale and multimodal 3D models of the brain are essential tools to understand its complex structural and functional organization. Neuroimaging techniques addressing different aspects of brain organization should be integrated in a reference space to enable topographically correct alignment and subsequent analysis of the various datasets and their modalities. The Waxholm Space (http://software.incf.org/software/waxholm-space) is a publicly available 3D coordinate-based standard reference space for the mapping and registration of neuroanatomical data in rodent brains. This paper provides a newly developed pipeline combining imaging and reconstruction steps with a novel registration strategy to integrate new neuroimaging modalities into the Waxholm Space atlas. As a proof of principle, we incorporated large scale high-resolution cyto-, muscarinic M2 receptor, and fiber architectonic images of rat brains into the 3D digital MRI based atlas of the Sprague Dawley rat in Waxholm Space. We describe the whole workflow, from image acquisition to reconstruction and registration of these three modalities into the Waxholm Space rat atlas. The registration of the brain sections into the atlas is performed by using both linear and non-linear transformations. The validity of the procedure is qualitatively demonstrated by visual inspection, and a quantitative evaluation is performed by measurement of the concordance between representative atlas-delineated regions and the same regions based on receptor or fiber architectonic data. This novel approach enables for the first time the generation of 3D reconstructed volumes of nerve fibers and fiber tracts, or of muscarinic M2 receptor density distributions, in an entire rat brain. Additionally, our pipeline facilitates the inclusion of further neuroimaging datasets, e.g., 3D reconstructed volumes of histochemical stainings or of the regional distributions of multiple other receptor types, into the Waxholm Space

  9. Architectural Mealscapes

    DEFF Research Database (Denmark)

    Tvedebrink, Tenna Doktor Olsen; Fisker, Anna Marie; Kirkegaard, Poul Henning

    2012-01-01

    German architect Gottfried Semper developed a theory on the “four elements of Architecture” tracing the origin of architecture back to the rise of the early human settlement and the creation of fire. With the notion ‘hearth’ as the first motive in architecture and the definition of three enclosing...... motives; mounding, enclosure and roof, Semper linked the cultural and social values of the primordial fireplace with the order and shape of architecture. He claimed that any building ever made was nothing but a variation of the first primitive shelters erected around the fireplace, and that the three...... enclosing motives existed only as defenders of the “sacred flame”. In that way Semper developed the idea that any architectural scenery can be described, analyzed and explained by understanding the contextual, symbolic and social values of how the four basic motives of hearth, mounding, enclosure, and roof...

  10. Framing Architecture

    OpenAIRE

    Shirey, David E.

    2002-01-01

    The following thesis is comprised of a pair of projects focused on the making of architecture through the concept of framing. The work was conducted at the Academia dà ­Architettura in Mendrisio, Switzerland, under the direction of Peter Zumthor, Miguel Kreisler and Myriam Sterling, emphasizing the relationship between ordered structures and contextual propriety. The making of architecture is inherently most pure when approached as the subtraction of unnecessary elements and a distillation ...

  11. Textile Architecture

    OpenAIRE

    Maurin, Bernard; Motro, René

    2013-01-01

    The basic idea for a textile architecture project originates during early meetings between the architect and the engineer. The morphologic richness of such projects is provided by the varying curvatures of shapes, in contradiction with a classical straight line and orthogonal architecture. However the rules of construction are quite different in terms of realisation and of mechanical behaviour: textile membranes are subjected to a pre-stress conferring them their rigidity, and a major objecti...

  12. Fractal Architecture

    OpenAIRE

    Rumież, Agnieszka

    2013-01-01

    Research focuses on the recognition of the disposition of natural environment, which serves as an inspiration for cultural creation as it has always been in the history of architecture. Modern mathematical model of fractal geometry has been used to understand patterns occurring in the surrounding. The comparative analysis has been conducted between the abstract mathematical model and architectural composition in the view of contemporary cognitive paradigms. In conclusion, a hypothesis of a ne...

  13. IAIMS Architecture

    OpenAIRE

    Hripcsak, George

    1997-01-01

    An information system architecture defines the components of a system and the interfaces among the components. A good architecture is essential for creating an Integrated Advanced Information Management System (IAIMS) that works as an integrated whole yet is flexible enough to accommodate many users and roles, multiple applications, changing vendors, evolving user needs, and advancing technology. Modularity and layering promote flexibility by reducing the complexity of...

  14. Software Architecture in Depth

    OpenAIRE

    Lars Heinemann; Christian Neumann; Birgit Penzenstadler; Wassiou Sitou

    2016-01-01

    The quality of software architecture is one of the crucial success factors for the development of large and/or complex systems. Therefore, a good software architect plays a key role in every demanding project: She or he has the overview of the overall system and sets the framework for the implementation. In order to be successful in this task, software architects need well-founded and encompassing knowledge about design, which exceeds pure programming and specific spe- cialization a...

  15. Educación e integración de saberes en la carrera de Arquitectura / Educating and integrating knowledge in Architecture studies

    Directory of Open Access Journals (Sweden)

    Chaos, Mabel Teresa

    2016-04-01

    Full Text Available El artículo muestra cómo es posible lograr un mayor impacto educativo mediante la integración de las disciplinas en el año a partir de la disciplina principal integradora. El objetivo del mismo es describir la experiencia alcanzada por el colectivo del segundo año de la carrera de Arquitectura en la integración de los saberes y las acciones educativas. A través de la investigación-acción se procuró integrar de manera armónica las acciones del colectivo de año y los estudiantes, recogidas en la Estrategia Educativa, las actividades del plan metodológico y los contenidos de las disciplinas del año que se integran para favorecer el desarrollo del pensamiento interdisciplinario de los estudiantes. Con la propuesta la disciplina principal integradora logra cumplimentar objetivos referentes a la formación integral, incluido el trabajo político ideológico con el estudiante, así como la formación en valores desde el contenido, al considerar un enfoque dialéctico del proceso docente-educativo y una conducción consciente y en forma óptima del mismo que permite alcanzar la preparación del profesional que necesita la sociedad. The paper argues how it is possible to achieve a larger impact of education by means of a comprehensive interdisciplinary approach. The objective is to describe the experience of a staff of professor that has been working with architecture sophomores in integrating contents and educative tasks. By means of a research-and-acting methodology, the authors engage in a process of harmonizing tasks included in the Education Strategy, teacher development project, and curricular contents. The author’s thesis was that integrating tasks would develop students’ comprehensive thinking. The proposal favors the accomplishment of the objective of education, particularly in achieving an all-around education and relating professional contents to morale by means of developing students’ sensitiveness and awareness as a

  16. Flexible and transparent silicon-on-polymer based sub-20 nm non-planar 3D FinFET for brain-architecture inspired computation

    KAUST Repository

    Sevilla, Galo T.

    2014-02-22

    An industry standard 8′′ silicon-on-insulator wafer based ultra-thin (1 μm), ultra-light-weight, fully flexible and remarkably transparent state-of-the-art non-planar three dimensional (3D) FinFET is shown. Introduced by Intel Corporation in 2011 as the most advanced transistor architecture, it reveals sub-20 nm features and the highest performance ever reported for a flexible transistor. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Architectural geometry

    KAUST Repository

    Pottmann, Helmut

    2014-11-26

    Around 2005 it became apparent in the geometry processing community that freeform architecture contains many problems of a geometric nature to be solved, and many opportunities for optimization which however require geometric understanding. This area of research, which has been called architectural geometry, meanwhile contains a great wealth of individual contributions which are relevant in various fields. For mathematicians, the relation to discrete differential geometry is significant, in particular the integrable system viewpoint. Besides, new application contexts have become available for quite some old-established concepts. Regarding graphics and geometry processing, architectural geometry yields interesting new questions but also new objects, e.g. replacing meshes by other combinatorial arrangements. Numerical optimization plays a major role but in itself would be powerless without geometric understanding. Summing up, architectural geometry has become a rewarding field of study. We here survey the main directions which have been pursued, we show real projects where geometric considerations have played a role, and we outline open problems which we think are significant for the future development of both theory and practice of architectural geometry.

  18. IAIMS architecture.

    Science.gov (United States)

    Hripcsak, G

    1997-01-01

    An information system architecture defines the components of a system and the interfaces among the components. A good architecture is essential for creating an Integrated Advanced Information Management System (IAIMS) that works as an integrated whole yet is flexible enough to accommodate many users and roles, multiple applications, changing vendors, evolving user needs, and advancing technology. Modularity and layering promote flexibility by reducing the complexity of a system and by restricting the ways in which components may interact. Enterprise-wide mediation promotes integration by providing message routing, support for standards, dictionary-based code translation, a centralized conceptual data schema, business rule implementation, and consistent access to databases. Several IAIMS sites have adopted a client-server architecture, and some have adopted a three-tiered approach, separating user interface functions, application logic, and repositories. PMID:9067884

  19. Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    Architecture and anthropology have always had a common focus on dwelling, housing, urban life and spatial organisation. Current developments in both disciplines make it even more relevant to explore their boundaries and overlaps. Architects are inspired by anthropological insights and methods......, while recent material and spatial turns in anthropology have also brought an increasing interest in design, architecture and the built environment. Understanding the relationship between the social and the physical is at the heart of both disciplines, and they can obviously benefit from further...... collaboration: How can qualitative anthropological approaches contribute to contemporary architecture? And just as importantly: What can anthropologists learn from architects’ understanding of spatial and material surroundings? Recent theoretical developments in anthropology stress the role of materials and...

  20. Architectural Narratives

    DEFF Research Database (Denmark)

    Kiib, Hans

    2010-01-01

    In this essay, I focus on the combination of programs and the architecture of cultural projects that have emerged within the last few years. These projects are characterized as “hybrid cultural projects,” because they intend to combine experience with entertainment, play, and learning. This essay...... identifies new rationales related to this development, and it argues that “cultural planning” has increasingly shifted its focus from a cultural institutional approach to a more market-oriented strategy that integrates art and business. The role of architecture has changed, too. It not only provides a...... functional framework for these concepts, but tries increasingly to endow the main idea of the cultural project with a spatially aesthetic expression - a shift towards “experience architecture.” A great number of these projects typically recycle and reinterpret narratives related to historical buildings and...

  1. Architectural Engineers

    DEFF Research Database (Denmark)

    Petersen, Rikke Premer

    engineering is addresses from two perspectives – as an educational response and an occupational constellation. Architecture and engineering are two of the traditional design professions and they frequently meet in the occupational setting, but at educational institutions they remain largely estranged. The...... paper builds on a multi-sited study of an architectural engineering program at the Technical University of Denmark and an architectural engineering team within an international engineering consultancy based on Denmark. They are both responding to new tendencies within the building industry where the...... role of engineers and architects increasingly overlap during the design process, but their approaches reflect different perceptions of the consequences. The paper discusses some of the challenges that design education, not only within engineering, is facing today: young designers must be equipped with...

  2. Mind and Language Architecture

    OpenAIRE

    Robert K. Logan

    2010-01-01

    A distinction is made between the brain and the mind. The architecture of the mind and language is then described within a neo-dualistic framework. A model for the origin of language based on emergence theory is presented. The complexity of hominid existence due to tool making, the control of fire and the social cooperation that fire required gave rise to a new level of order in mental activity and triggered the simultaneous emergence of language and conceptual thought. The mind is shown to h...

  3. Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    and other spaces that architects are preoccupied with. On the other hand, the distinction between architecture and design is not merely one of scale. Design and architecture represent – at least in Denmark – also quite different disciplinary traditions and methods. Where designers develop prototypes......, architects tend to work with models and plans that are not easily understood by lay people. Further, many architects are themselves sceptical towards notions of user-involvement and collaborative design. They fear that the imagination of citizens and users is restricted to what they are already familiar with...

  4. Reframing Architecture

    DEFF Research Database (Denmark)

    Riis, Søren

    2013-01-01

    I would like to thank Prof. Stephen Read (2011) and Prof. Andrew Benjamin (2011) for both giving inspiring and elaborate comments on my article “Dwelling in-between walls: the architectural surround”. As I will try to demonstrate below, their two different responses not only supplement my article...... focuses on how the absence of an initial distinction might threaten the endeavour of my paper. In my reply to Read and Benjamin, I will discuss their suggestions and arguments, while at the same time hopefully clarifying the postphenomenological approach to architecture....

  5. Multithreading architecture

    CERN Document Server

    Nemirovsky, Mario

    2013-01-01

    Multithreaded architectures now appear across the entire range of computing devices, from the highest-performing general purpose devices to low-end embedded processors. Multithreading enables a processor core to more effectively utilize its computational resources, as a stall in one thread need not cause execution resources to be idle. This enables the computer architect to maximize performance within area constraints, power constraints, or energy constraints. However, the architectural options for the processor designer or architect looking to implement multithreading are quite extensive and

  6. Microprocessor architectures RISC, CISC and DSP

    CERN Document Server

    Heath, Steve

    1995-01-01

    'Why are there all these different processor architectures and what do they all mean? Which processor will I use? How should I choose it?' Given the task of selecting an architecture or design approach, both engineers and managers require a knowledge of the whole system and an explanation of the design tradeoffs and their effects. This is information that rarely appears in data sheets or user manuals. This book fills that knowledge gap.Section 1 provides a primer and history of the three basic microprocessor architectures. Section 2 describes the ways in which the architectures react with the

  7. Architecture and Stages of the Experience City

    DEFF Research Database (Denmark)

    This book presents more than 41 articles on ‘Architecture and Stages of the Experience City'. The aim of the book is to investigate current challenges related to architecture, art and city life in the ‘Experience City' and it is presenting cutting edge knowledge and experiences within the following...... themes: Experience City Making Digital Architecture Stages in the Experience City The City as a Learning Lab Experience City Architecture Performative Architecture Art and Performance Urban Catalyst and Temporary Use...

  8. From green architecture to architectural green

    DEFF Research Database (Denmark)

    Earon, Ofri

    2011-01-01

    The paper investigates the topic of green architecture from an architectural point of view and not an energy point of view. The purpose of the paper is to establish a debate about the architectural language and spatial characteristics of green architecture. In this light, green becomes an adjective...... that describes the architectural exclusivity of this particular architecture genre. The adjective green expresses architectural qualities differentiating green architecture from none-green architecture. Currently, adding trees and vegetation to the building’s facade is the main architectural characteristics...... of green architecture. The paper argues that this greenification of facades is insufficient. The green is only a skin cladding the exterior envelope without having a spatial significance. Through the paper it is proposed to flip the order of words from green architecture to architectural green...

  9. Religious Architecture

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The main religions of ancient China were Buddhism,Taoism and Islam, of which Buddhism was the most widespread. As a result, Buddhist temples and towers are found all over China, and have become important components of the country's ancient architecture.

  10. Avaliação do conhecimento de estudantes de medicina sobre morte encefálica Evaluation of medical students knowledge on brain death

    Directory of Open Access Journals (Sweden)

    Almir Galvão Vieira Bitencourt

    2007-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Por ser um conceito relativamente novo e pouco divulgado na sociedade, o diagnóstico de morte encefálica (ME ainda não é bem aceito pela população em geral, inclusive entre médicos e estudantes de Medicina. O objetivo deste estudo foi avaliar o conhecimento de uma amostra de estudantes de Medicina sobre o protocolo diagnóstico de ME. MÉTODO: Estudo descritivo de corte transversal, avaliando acadêmicos de duas faculdades de Medicina de Salvador-BA. Foi distribuído um questionário auto-aplicável composto por questões referentes à conhecimento, técnico e ético, contidos na Resolução nº 1.480/97 do Conselho Federal de Medicina, que dispõe sobre os critérios para caracterização de ME. RESULTADOS: Foram avaliados 115 estudantes. A média de acertos nas 14 questões sobre o conhecimento dos critérios da ME foi de 6,7 ± 1,8; sendo maior entre os estudantes que haviam assistido alguma apresentação sobre ME. A maioria dos estudantes (87,4% soube identificar os pacientes candidatos ao protocolo de ME. No entanto, apenas 5,2% e 16,1% dos estudantes acertaram, respectivamente, os testes clínicos e complementares que devem ser realizados durante o protocolo. Frente a um paciente não-doador com diagnóstico confirmado de ME, 66,4% referiram que o suporte artificial de vida deve ser suspenso. Apenas 15% dos estudantes entrevistados já avaliaram um paciente com ME, sendo este percentual maior entre os que já haviam realizado estágio em UTI (38,2% versus 5,1%; p BACKGROUND AND OBJECTIVES: Because brain death (BD is a new concept and little divulged, it’s not well accepted in general population, including doctors and Medical students. This study aims to evaluate the knowledge of a sample of Medical students on the Brazilian BD diagnosis protocol. METHODS: Descriptive cross-sectional survey that evaluated students from two medical schools in Salvador-BA. We used a questionnaire composed by questions

  11. Kosmos = architecture

    Directory of Open Access Journals (Sweden)

    Tine Kurent

    2015-10-01

    Full Text Available The old Greek word "kosmos" means not only "cosmos", but also "the beautiful order", "the way of building", "building", "scenography", "mankind", and, in the time of the New Testament, also "pagans". The word "arhitekton", meaning first the "master of theatrical scenography", acquired the meaning of "builder", when the words "kosmos" and ~kosmetes" became pejorative. The fear that architecture was not considered one of the arts before Renaissance, since none of the Muses supervised the art of building, results from the misunderstanding of the word "kosmos". Urania was the Goddes of the activity implied in the verb "kosmein", meaning "to put in the beautiful order" - everything, from the universe to the man-made space, i. e. the architecture.

  12. MUF architecture /art London

    DEFF Research Database (Denmark)

    Svenningsen Kajita, Heidi

    2009-01-01

    Om MUF architecture samt interview med Liza Fior og Katherine Clarke, partnere i muf architecture/art......Om MUF architecture samt interview med Liza Fior og Katherine Clarke, partnere i muf architecture/art...

  13. Architectural Qualities in Passive Houses

    DEFF Research Database (Denmark)

    Brunsgaard, Camilla

    2012-01-01

    In recent years in Denmark there has been an increasing focus on implementing passive and active strategies in buildings to fulfil low energy demands like for example the Passive House Standard. From a technical rational perspective, plenty of pilot projects and commercial projects have shown that...... it is possible to build this type of houses, but the knowledge and discussion about the architectural quality in the buildings is hardly present. The question is if the strategies for optimising energy use and indoor environment collide with the architectural qualities of buildings. This paper brings...... forth this discussion based in literature and four case studies. The paper highlights cases on how passive strategies for optimising energy use and indoor environment affect, restrict, inspire or create possibilities for the architectural expression and there through the architectural quality of the...

  14. Executable Architecture Research at Old Dominion University

    Science.gov (United States)

    Tolk, Andreas; Shuman, Edwin A.; Garcia, Johnny J.

    2011-01-01

    Executable Architectures allow the evaluation of system architectures not only regarding their static, but also their dynamic behavior. However, the systems engineering community do not agree on a common formal specification of executable architectures. To close this gap and identify necessary elements of an executable architecture, a modeling language, and a modeling formalism is topic of ongoing PhD research. In addition, systems are generally defined and applied in an operational context to provide capabilities and enable missions. To maximize the benefits of executable architectures, a second PhD effort introduces the idea of creating an executable context in addition to the executable architecture. The results move the validation of architectures from the current information domain into the knowledge domain and improve the reliability of such validation efforts. The paper presents research and results of both doctoral research efforts and puts them into a common context of state-of-the-art of systems engineering methods supporting more agility.

  15. Haptic architecture becomes architectural hap

    OpenAIRE

    Herssens, Jasmien; Heylighen, Ann

    2007-01-01

    Universal Design is a recent design paradigm which aims at handicap elimination in the physical environment and strives for a more humanized architecture. After pointing out the value of Universal Design, the paper advances human centred design as a possible methodology to make this paradigm operational. Key to this methodology is the explicit attention for cognitive human factors in experiencing space and—the focus of this paper—for the role played by the sense of tou...

  16. Leading research on brain functional information processing; No kino joho shori no sendo kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This research aims at searching the concept of an information processing device with a fully different architecture from a previous ones based on the study on human brain function, sense and perception, and developing the basic fabrication technology for such system, and realizing the human-like information processing mechanism of memorization, learning, association, perception, intuition and value judgement. As an approach deriving biological and technological models from experimental brain studies, the model was derived from the brain functional information processing based on brain development/differentiation mechanism, the control mechanism/material of brain activities, and the knowledge obtained from brain measurement and study. In addition, for understanding a brain oscillation phenomenon by computational neuroscience, the cerebral cortex neural network model composed of realistic neuron models was proposed. Evaluation of the previous large-scale neural network chip system showed its ability of learning and fast processing, however, the next-generation brain computer requires further R and D of some novel architecture, device and system. 184 refs., 41 figs., 2 tabs.

  17. Textile Architecture

    DEFF Research Database (Denmark)

    Heimdal, Elisabeth Jacobsen

    2010-01-01

    Textiles can be used as building skins, adding new aesthetic and functional qualities to architecture. Just like we as humans can put on a coat, buildings can also get dressed. Depending on our mood, or on the weather, we can change coat, and so can the building. But the idea of using textiles...... to create human habitation is not new. As Diether S. Hope phrases it, referring to tents: The history of development of humanity would be barely conceivable without free spanning textile membrane structures....

  18. A conceptual architecture for interactive educational multimedia

    OpenAIRE

    Pahl, Claus

    2007-01-01

    Learning is more than knowledge acquisition; it often involves the active participation of the learner in a variety of knowledge- and skills-based learning and training activities. Interactive multimedia technology can support the variety of interaction channels and languages required to facilitate interactive learning and teaching. A conceptual architecture for interactive educational multimedia can support the development of such multimedia systems. Such an architecture needs to embed m...

  19. Knowledge about knowledge

    International Nuclear Information System (INIS)

    Technology and knowledge make up the knowledge capital that has been so essential to the oil and gas industry's value creation, competitiveness and internationalization. Report prepared for the Norwegian Oil Industry Association (OLF) and The Norwegian Society of Chartered Technical and Scientific Professionals (Tekna), on the Norwegian petroleum cluster as an environment for creating knowledge capital from human capital, how fiscal and other framework conditions may influence the building of knowledge capital, the long-term perspectives for the petroleum cluster, what Norwegian society can learn from the experiences in the petroleum cluster, and the importance of gaining more knowledge about the functionality of knowledge for increased value creation (author) (ml)

  20. Exploring brain function from anatomical connectivity

    Directory of Open Access Journals (Sweden)

    Gorka Zamora-López

    2011-06-01

    Full Text Available The intrinsic relationship between the architecture of the brain and the range of sensory and behavioral phenomena it produces is a relevant question in neuroscience. Here, we review recent knowledge gained on the architecture of the anatomical connectivity by means of complex network analysis. It has been found that corticocortical networks display a few prominent characteristics: (i modular organization, (ii abundant alternative processing paths and (iii the presence of highly connected hubs. Additionally, we present a novel classification of cortical areas of the cat according to the role they play in multisensory connectivity. All these properties represent an ideal anatomical substrate supporting rich dynamical behaviors, as-well-as facilitating the capacity of the brain to process sensory information of different modalities segregated and to integrate them towards a comprehensive perception of the real world. The result here exposed are mainly based in anatomical data of cats’ brain, but we show how further observations suggest that, from worms to humans, the nervous system of all animals might share fundamental principles of organization.

  1. Software design by reusing architectures

    Science.gov (United States)

    Bhansali, Sanjay; Nii, H. Penny

    1992-01-01

    Abstraction fosters reuse by providing a class of artifacts that can be instantiated or customized to produce a set of artifacts meeting different specific requirements. It is proposed that significant leverage can be obtained by abstracting software system designs and the design process. The result of such an abstraction is a generic architecture and a set of knowledge-based, customization tools that can be used to instantiate the generic architecture. An approach for designing software systems based on the above idea are described. The approach is illustrated through an implemented example, and the advantages and limitations of the approach are discussed.

  2. Neurocomputational models of brain disorders

    NARCIS (Netherlands)

    Cutsuridis, Vassilis; Heida, Tjitske; Duch, Wlodek; Doya, Kenji

    2011-01-01

    Recent decades have witnessed dramatic accumulation of knowledge about the genetic, molecular, pharmacological, neurophysiological, anatomical, imaging and psychological characteristics of brain disorders. Despite these advances, however, experimental brain science has offered very little insight in

  3. Decoding the architectural theory

    Institute of Scientific and Technical Information of China (English)

    Gu Mengchao

    2008-01-01

    Starting from the illustration of the definition and concept of the architectural theory, the author established his unique understanding about the framework of the architectural theory and the innovation of the architectural theory underlined by Chinese characteristics.

  4. A computational architecture for social agents

    Energy Technology Data Exchange (ETDEWEB)

    Bond, A.H. [California Institute of Technology, Pasadena, CA (United States)

    1996-12-31

    This article describes a new class of information-processing models for social agents. They axe derived from primate brain architecture, the processing in brain regions, the interactions among brain regions, and the social behavior of primates. In another paper, we have reviewed the neuroanatomical connections and functional involvements of cortical regions. We reviewed the evidence for a hierarchical architecture in the primate brain. By examining neuroanatomical evidence for connections among neural areas, we were able to establish anatomical regions and connections. We then examined evidence for specific functional involvements of the different neural axeas and found some support for hierarchical functioning, not only for the perception hierarchies but also for the planning and action hierarchy in the frontal lobes.

  5. Preserving Architectural Decisions through Architectural Patterns

    OpenAIRE

    Thon That, Minh Tu; Sadou, Salah; Oquendo, F.; Fleurquin, R

    2014-01-01

    International audience Architectural decisions have emerged as a means to maintain the quality of the architecture during its evolution. One of the most important de-cisions made by architects are those about the design approach such as the use of patterns or styles in the architecture. The structural nature of this type of decisions give them the potential to be controlled systematically. In the litera-ture, there are some works on the automation of architectural decision violation checki...

  6. Software Architecture Simulation

    OpenAIRE

    Mårtensson, Frans; Jönsson, Per

    2002-01-01

    A software architecture is one of the first steps towards a software system. A software architecture can be designed in different ways. During the design phase, it is important to select the most suitable design of the architecture, in order to create a good foundation for the system. The selection process is performed by evaluating architecture alternatives against each other. We investigate the use of continuous simulation of a software architecture as a support tool for architecture evalua...

  7. Critical Factors in the Effective of Service-Oriented Architecture

    OpenAIRE

    Sima Emadi; Raziye Hatami Hanza

    2013-01-01

    Service oriented architecture is a style of architecture, design and develop service more flexible and reusable. Service-oriented architecture is a great challenge in the scientific and practical, and has done a lot of research in this field. But some studies have also shown that it has failed to implement the project. A major reason for failure is lack of knowledge about critical factor in the success of service-oriented architecture. This paper, Provided critical factors in the successful i...

  8. Architectures of prototypes and architectural prototyping

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Christensen, Michael; Sandvad, Elmer;

    1998-01-01

    sessions with users, - evolve over a long period of time to contain more functionality - allow for 6-7 developers working intensively in parallel. Explicit focus on the software architecture and letting the architecture evolve with the prototype played a major role in resolving these conflicting...... constraints. Specifically allowing explicit restructuring phases when the architecture became problematic showed to be crucial.  ...

  9. Software architecture 2

    CERN Document Server

    Oussalah, Mourad Chabanne

    2014-01-01

    Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural templa

  10. Lightweight enterprise architectures

    CERN Document Server

    Theuerkorn, Fenix

    2004-01-01

    STATE OF ARCHITECTUREArchitectural ChaosRelation of Technology and Architecture The Many Faces of Architecture The Scope of Enterprise Architecture The Need for Enterprise ArchitectureThe History of Architecture The Current Environment Standardization Barriers The Need for Lightweight Architecture in the EnterpriseThe Cost of TechnologyThe Benefits of Enterprise Architecture The Domains of Architecture The Gap between Business and ITWhere Does LEA Fit? LEA's FrameworkFrameworks, Methodologies, and Approaches The Framework of LEATypes of Methodologies Types of ApproachesActual System Environmen

  11. Software architecture 1

    CERN Document Server

    Oussalah , Mourad Chabane

    2014-01-01

    Over the past 20 years, software architectures have significantly contributed to the development of complex and distributed systems. Nowadays, it is recognized that one of the critical problems in the design and development of any complex software system is its architecture, i.e. the organization of its architectural elements. Software Architecture presents the software architecture paradigms based on objects, components, services and models, as well as the various architectural techniques and methods, the analysis of architectural qualities, models of representation of architectural template

  12. Healing Architecture

    DEFF Research Database (Denmark)

    Folmer, Mette Blicher; Mullins, Michael; Frandsen, Anne Kathrine

    2012-01-01

    ’s backstage-frontstage theory and Lawsons ‘Language of Space’ is used. Data is analyzed in accordance with principles describes in Robert Yin’s ‘Case Study Research’. The goal of the project is to create new knowledge which can contribute to new ways to design, plan and organize the hospital and qualify....... The project is an explorative case study and consists of systematic observations, interviews and photo documentation. The aim is to collect different kinds of data on: 1. Relatives’ behavior 2. Relatives’ experience and 3. Environment. In order to guide the collection of data and the analysis of them Goffman...

  13. The Changes in Architecture Terminology

    Directory of Open Access Journals (Sweden)

    Francois Tran

    2012-10-01

    Full Text Available The intention of this research is to inspire a discussion about the changes in architecture terminologywith the revolution in communication and representation forms as a result of digitalisation.The blurred boundary between the virtual and the analogue worlds, the misunderstandings andthe confusion that appear with the interaction of these two worlds nowadays form the major problems facing architectural design, education and research. The researchers in this field arefocused on the interface, the meeting and the transformation point between the digital and analogue worlds in order to prevent those problems and confusions. One of the main reasonsof this ambiguity is the architectural terminology that changes according to the changing status of architectural representation i.e. new forms of representation; new forms of communicationi.e. the new role of the architect and the researcher.Whenever and wherever information and knowledge specialised is created, communicated ortransformed terminology is involved in a way or another. An absence of terminology is combined with an absence of an understanding of concepts. Therefore with the new information and communication technologies; new and developing subject areas the existence of terminology and its update is indispensable. Thus the changing status of the terminology must be analysed. As architecture terminology is essential to improve today’s challenging, multidisciplinary communication in order to clarify the problems of ambiguity and unawareness (as a result of shift of specific architectural vocabulary it is necessary to analyse the changes in the architectural terminology which will form the discussion point of the following paper.As this paper is the beginning step of a research project which started on the occasion of the conference proposed by EAAE/ARCC we will here present only the objectives of this research,its general problematics, the methods that we wish to develop and some provisional

  14. Lunar Navigation Architecture Design Considerations

    Science.gov (United States)

    D'Souza, Christopher; Getchius, Joel; Holt, Greg; Moreau, Michael

    2009-01-01

    The NASA Constellation Program is aiming to establish a long-term presence on the lunar surface. The Constellation elements (Orion, Altair, Earth Departure Stage, and Ares launch vehicles) will require a lunar navigation architecture for navigation state updates during lunar-class missions. Orion in particular has baselined earth-based ground direct tracking as the primary source for much of its absolute navigation needs. However, due to the uncertainty in the lunar navigation architecture, the Orion program has had to make certain assumptions on the capabilities of such architectures in order to adequately scale the vehicle design trade space. The following paper outlines lunar navigation requirements, the Orion program assumptions, and the impacts of these assumptions to the lunar navigation architecture design. The selection of potential sites was based upon geometric baselines, logistical feasibility, redundancy, and abort support capability. Simulated navigation covariances mapped to entry interface flightpath- angle uncertainties were used to evaluate knowledge errors. A minimum ground station architecture was identified consisting of Goldstone, Madrid, Canberra, Santiago, Hartebeeshoek, Dongora, Hawaii, Guam, and Ascension Island (or the geometric equivalent).

  15. Knowledge management

    OpenAIRE

    Jarošová, Milena

    2010-01-01

    Theoretical part: Basic terms of knowledge management, knowledge worker, knowledge creation and conversion process, prerequisites and benefits of knowledge management. Knowledge management and it's connection to organizational culture and structure, result measurements of knowledge management, learning organization and it's connection to knowledge management. Tacit knowledge management tools -- stories -- types, how to create, practical use, communities, coaching. Value Based Organization. Pr...

  16. “What” and “how”: Evidence for the dissociation of object knowledge and mechanical problem-solving skills in the human brain

    OpenAIRE

    Hodges, John R; Spatt, Josef; Patterson, Karalyn

    1999-01-01

    Patients with profound semantic deterioration resulting from temporal lobe atrophy have been reported to use many real objects appropriately. Does this preserved ability reflect (i) a separate component of the conceptual knowledge system (“action semantics”) or (ii) the operation of a system that is independent of conceptual knowledge of specific objects, and rather is responsible for general mechanical problem-solving skills, triggered by object affordances? We contrast the performance of th...

  17. Cluster-level Architectural Knowledge and Its Creation Mechanisms Analysis---Case Studies Based on Dalian Software Park%集群体系知识及其创造机制分析*--基于大连软件园的案例研究

    Institute of Scientific and Technical Information of China (English)

    李浩; 黄剑; 张红杰

    2016-01-01

    [Purpose / Significance] The cluster-level architectural knowledge is the source to maintain sustainable competitive advantage of clusters, but it's content and dimension lack authority definition, and it's creation mechanisms are in the black box. Revealing the characteristics of cluster-level architectural knowledge and creation mechanisms for each elements of cluster-level architectural knowledge in favor of the enrich and improvement to the knowledge-based theory of clusters, and promote the development of cluster innovation and competitive advantage theory. [Method / Process] This article uses the research method of the single case, chose Dalian Software Park as the research object. By collecting interview data, archival data and documents, we cross validate the second-hand information and firsthand information, and use grounded theory to finish data coding and analysis. [Results / Conclusions] We extract the institution, industrial atmosphere, convention and universal mutual benefit as the constituent elements of cluster-level architectural knowledge, and the cluster -level architectural knowledge is divided into three dimensions, namely the dominant dimension, spontaneous dimension and interdependent dimensions. It reveals the cluster system has partial tacit knowledge, rooted, integration, path dependence and knowledge barriers of five properties, further elaborated system of knowledge creation mechanism.%[目的/意义]集群体系知识为集群及其成员带来可持续的整体竞争优势,但其内容维度和特性尚缺乏权威阐释,体系知识的创造机制还处于黑箱状态,揭示体系知识的内容维度及创造机制有利于丰富和完善集群知识理论,并推动集群创新和集群竞争优势理论的发展。[方法/过程]采用单案例的研究方法,选择了大连软件园作为研究对象,通过收集访谈数据、档案数据和文件资料,将所获得的二手资料与一手资料交叉验证,并运

  18. Research of IDSS Architecture Based on Hybrid Systems

    Institute of Scientific and Technical Information of China (English)

    MA Biao; YANG Bao-an

    2005-01-01

    This paper discusses the necessity of building IDSS on hybrid systems, and adopts XML technology to manage isomeric knowledge in hybrid systems. The paper proposes a new architecture of hybrid systems based IDSS whose core system is isomeric knowledge system. The architecture is composed of knowledge component, problems processing system, data component and intelligent user interface. This new architecture aims to enhance the capability of integrating hybrid systems, to improve the supporting effectiveness of decision-making and the intelligent level of IDSS, and tries a new way to elevate the system's ability of handling and learning knowledge.

  19. Knowledge Uncertainty and Composed Classifier

    Czech Academy of Sciences Publication Activity Database

    Klimešová, Dana; Ocelíková, E.

    2007-01-01

    Roč. 1, č. 2 (2007), s. 101-105. ISSN 1998-0140 Institutional research plan: CEZ:AV0Z10750506 Keywords : Boosting architecture * contextual modelling * composed classifier * knowledge management , * knowledge * uncertainty Subject RIV: IN - Informatics, Computer Science

  20. Preindustrial versus postindustrial Architecture and Building Techniques

    DEFF Research Database (Denmark)

    Vestergaard, Inge

    2014-01-01

    How can preindustrial architecture inspire sustainable thinking in postindustrial architectural design? How can we learn from experience and how can social, economic and environmental conditions give perspectives and guide a knowledge based evolution of basic experience towards modern industriali......How can preindustrial architecture inspire sustainable thinking in postindustrial architectural design? How can we learn from experience and how can social, economic and environmental conditions give perspectives and guide a knowledge based evolution of basic experience towards modern...... industrialized building processes? Identification of sustainable parameters related to change in society, to building technique and to comfort are illustrated through two Danish building types, which are different in time, but similar in function. One representing evolution and experience based countryside...

  1. Legionella micdadei Brain Abscess

    OpenAIRE

    Charles, Marthe; Johnson, Edward; Macyk-Davey, Andrea; Henry, Monica; Nilsson, Jan-Erik; Miedzinski, Lil; Zahariadis, George

    2013-01-01

    We describe an immunocompromised patient who developed a large frontal brain abscess caused by Legionella micdadei. This is, to our knowledge, a rare case of culture-proven Legionella central nervous system infection.

  2. Knowledge-guided robust MRI brain extraction for diverse large-scale neuroimaging studies on humans and non-human primates.

    Directory of Open Access Journals (Sweden)

    Yaping Wang

    Full Text Available Accurate and robust brain extraction is a critical step in most neuroimaging analysis pipelines. In particular, for the large-scale multi-site neuroimaging studies involving a significant number of subjects with diverse age and diagnostic groups, accurate and robust extraction of the brain automatically and consistently is highly desirable. In this paper, we introduce population-specific probability maps to guide the brain extraction of diverse subject groups, including both healthy and diseased adult human populations, both developing and aging human populations, as well as non-human primates. Specifically, the proposed method combines an atlas-based approach, for coarse skull-stripping, with a deformable-surface-based approach that is guided by local intensity information and population-specific prior information learned from a set of real brain images for more localized refinement. Comprehensive quantitative evaluations were performed on the diverse large-scale populations of ADNI dataset with over 800 subjects (55 ∼ 90 years of age, multi-site, various diagnosis groups, OASIS dataset with over 400 subjects (18 ∼ 96 years of age, wide age range, various diagnosis groups, and NIH pediatrics dataset with 150 subjects (5 ∼ 18 years of age, multi-site, wide age range as a complementary age group to the adult dataset. The results demonstrate that our method consistently yields the best overall results across almost the entire human life span, with only a single set of parameters. To demonstrate its capability to work on non-human primates, the proposed method is further evaluated using a rhesus macaque dataset with 20 subjects. Quantitative comparisons with popularly used state-of-the-art methods, including BET, Two-pass BET, BET-B, BSE, HWA, ROBEX and AFNI, demonstrate that the proposed method performs favorably with superior performance on all testing datasets, indicating its robustness and effectiveness.

  3. Creating product line architectures

    OpenAIRE

    Bayer, J.; Flege, O.; Gacek, C.

    2000-01-01

    The creation and validation of product line software architectures are inherently more complex than those of software architectures for single systems. This paper compares a process for creating and evaluating a traditional, one-of-a- kind software architecture with one for a reference software architecture. The comparison is done in the context of PuLSE-DSSA, a customizable process that integrates both product line architecture creation and evaluation.

  4. ESA: Enterprise Service Architecture

    OpenAIRE

    2010-01-01

    The Service oriented perspective is emerging as an important view both for business architecture and IT architecture in the overall context of enterprise architectures. Many existing enterprise architecture frameworks like DODAF, MODAF and NAF have lately been extended with service-oriented views. The UPDM UML Profile and Metamodel for DODAF and MODAF has thus included various service-oriented views. This thesis proposes a new enterprise architecture framework ESA Enterprise Service Arch...

  5. In pursuit of resilience: stress, epigenetics, and brain plasticity.

    Science.gov (United States)

    McEwen, Bruce S

    2016-06-01

    The brain is the central organ for adaptation to experiences, including stressors, which are capable of changing brain architecture as well as altering systemic function through neuroendocrine, autonomic, immune, and metabolic systems. Because the brain is the master regulator of these systems, as well as of behavior, alterations in brain function by chronic stress can have direct and indirect effects on cumulative allostatic overload, which refers to the cost of adaptation. There is much new knowledge on the neural control of systemic physiology and the feedback actions of physiologic mediators on brain regions regulating higher cognitive function, emotional regulation, and self-regulation. The healthy brain has a considerable capacity for resilience, based upon its ability to respond to interventions designed to open "windows of plasticity" and redirect its function toward better health. As a result, plasticity-facilitating treatments should be given within the framework of a positive behavioral intervention; negative experiences during this window may even make matters worse. Indeed, there are no magic bullets and drugs cannot substitute for targeted interventions that help an individual become resilient, of which mindfulness-based stress reduction and meditation are emerging as useful tools. PMID:26919273

  6. Marshall Application Realignment System (MARS) Architecture

    Science.gov (United States)

    Belshe, Andrea; Sutton, Mandy

    2010-01-01

    The Marshall Application Realignment System (MARS) Architecture project was established to meet the certification requirements of the Department of Defense Architecture Framework (DoDAF) V2.0 Federal Enterprise Architecture Certification (FEAC) Institute program and to provide added value to the Marshall Space Flight Center (MSFC) Application Portfolio Management process. The MARS Architecture aims to: (1) address the NASA MSFC Chief Information Officer (CIO) strategic initiative to improve Application Portfolio Management (APM) by optimizing investments and improving portfolio performance, and (2) develop a decision-aiding capability by which applications registered within the MSFC application portfolio can be analyzed and considered for retirement or decommission. The MARS Architecture describes a to-be target capability that supports application portfolio analysis against scoring measures (based on value) and overall portfolio performance objectives (based on enterprise needs and policies). This scoring and decision-aiding capability supports the process by which MSFC application investments are realigned or retired from the application portfolio. The MARS Architecture is a multi-phase effort to: (1) conduct strategic architecture planning and knowledge development based on the DoDAF V2.0 six-step methodology, (2) describe one architecture through multiple viewpoints, (3) conduct portfolio analyses based on a defined operational concept, and (4) enable a new capability to support the MSFC enterprise IT management mission, vision, and goals. This report documents Phase 1 (Strategy and Design), which includes discovery, planning, and development of initial architecture viewpoints. Phase 2 will move forward the process of building the architecture, widening the scope to include application realignment (in addition to application retirement), and validating the underlying architecture logic before moving into Phase 3. The MARS Architecture key stakeholders are most

  7. Software engineering architecture-driven software development

    CERN Document Server

    Schmidt, Richard F

    2013-01-01

    Software Engineering: Architecture-driven Software Development is the first comprehensive guide to the underlying skills embodied in the IEEE's Software Engineering Body of Knowledge (SWEBOK) standard. Standards expert Richard Schmidt explains the traditional software engineering practices recognized for developing projects for government or corporate systems. Software engineering education often lacks standardization, with many institutions focusing on implementation rather than design as it impacts product architecture. Many graduates join the workforce with incomplete skil

  8. Building science of indian temple architecture

    OpenAIRE

    Vardia, Shweta

    2008-01-01

    Master’s Thesis Structural Analysis of Monuments and Historical Constructions Every style of building construction reflects a clearly distinctive basic principle that represents a particular culture and era. In this context the Indian Hindu temple architecture are not only the abode of God and place of worship, but they are also the cradle of knowledge, art, architecture and culture. The practices and traditions of temples exist not only in history but also in present time which g...

  9. ARQUITECTURAS INVISIBLES / Invisible Architecture

    Directory of Open Access Journals (Sweden)

    Francisco Javier Montero Fernández

    2012-11-01

    Full Text Available RESUMEN El concurso siempre ha sido una herramienta de investigación necesitada de una puesta al día de los conocimientos: difundiendo los logros alcanzados se muestra también la exigente actualización del arquitecto de una manera integral. No todos los concursos son iguales, ni pretenden los mismos objetivos y en un gran número, desgraciadamente, han servido de camuflaje a cuestiones que van más allá de la calidad. Intereses políticos o comerciales tienden a confundir la oportunidad de la difusión con la bondad del proyecto. Sería posible enumerar numerosos concursos que en el último siglo han supuesto un avance significativo en la arquitectura; una cierta añoranza de aquellos tiempos de debate -bienales y trienales- o de otras fórmulas, como las exposiciones internaciones, que eran capaces de llevar la investigación empírica desde la práctica directa. Hoy, por el contrario, a menudo, la definición del marco de actuación del proyecto arquitectónico se define de una manera ajena a la propia arquitectura, administrativamente dominado por un proceso que prima el cumplimiento legal y técnico frente a la calidad del propio proyecto, confundiendo el medio con el fin. La crítica apunta siempre al autor; se olvidan los excelentes procedimientos que armaron a un jurado exonerado de responsabilidad de manera gratuita o ese marco legal que tanto asfixia a la arquitectura en contra del espíritu investigador que siempre debiera prevalecer.Este numero se plantea como la asimilación del concurso a un proceso de investigación paralelo a una arquitectura unida a la calidad y el progreso, una arquitectura avanzada.SUMMARY The competition has always been a research tool in need of a knowledge update: the broadcasting of achievements also demonstrates the need for an integrated update of the architect. Not all competitions are equal or set the same objectives, and, unfortunately, to a large extent, they have served as camouflage for

  10. Brain Basics

    Medline Plus

    Full Text Available ... News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The Working Brain ... to mental disorders, such as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are ...

  11. Brain Basics

    Science.gov (United States)

    ... News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The Working Brain ... to mental disorders, such as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are ...

  12. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... learning more about how the brain grows and works in healthy people, and how normal brain development ...

  13. "Tacit Knowledge" versus "Explicit Knowledge"

    OpenAIRE

    Sanchez, Ron

    2004-01-01

    This paper explains two fundamental approaches to knowledge management. The tacit knowledge approach emphasizes understanding the kinds of knowledge that individuals in an organization have, moving people to transfer knowledge within an organization, and managing key individuals as knowledge creators and carriers. By contrast, the explicit knowledge approach emphasizes processes for articulating knowledge held by individuals, the design of organizational approaches for creating...

  14. Critical Factors in the Effective of Service-Oriented Architecture

    Directory of Open Access Journals (Sweden)

    Sima Emadi

    2013-07-01

    Full Text Available Service oriented architecture is a style of architecture, design and develop service more flexible and reusable. Service-oriented architecture is a great challenge in the scientific and practical, and has done a lot of research in this field. But some studies have also shown that it has failed to implement the project. A major reason for failure is lack of knowledge about critical factor in the success of service-oriented architecture. This paper, Provided critical factors in the successful implementation of service oriented architecture and has reviewed Papers in this subject.

  15. Readout Architecture for Hybrid Pixel Readout Chips

    CERN Document Server

    AUTHOR|(SzGeCERN)694170; Westerlund, Tomi; Wyllie, Ken

    The original contribution of this thesis to knowledge are novel digital readout architectures for hybrid pixel readout chips. The thesis presents asynchronous bus-based architecture, a data-node based column architecture and a network-based pixel matrix architecture for data transportation. It is shown that the data-node architecture achieves readout efficiency 99 % with half the output rate as a bus-based system. The network-based solution avoids ``broken'' columns due to some manufacturing errors, and it distributes internal data traffic more evenly across the pixel matrix than column-based architectures. An improvement of $>$ 10 % to the efficiency is achieved with uniform and non-uniform hit occupancies. Architectural design has been done using transaction level modeling ($TLM$) and sequential high-level design techniques for reducing the design and simulation time. It has been possible to simulate tens of column and full chip architectures using the high-level techniques. A decrease of $>$ 10 in run-time...

  16. Rhein-Ruhr architecture

    DEFF Research Database (Denmark)

    2002-01-01

    katalog til udstillingen 'Rhein - Ruhr architecture' Meldahls smedie, 15. marts - 28. april 2002. 99 sider......katalog til udstillingen 'Rhein - Ruhr architecture' Meldahls smedie, 15. marts - 28. april 2002. 99 sider...

  17. Bioclimatism in vernacular architecture

    OpenAIRE

    Coch Roura, Helena

    1998-01-01

    Any analysis of the role played by energy in architecture is faced with serious limitations due to the lack of studies in the architectural bibliography, especially studies of popular architecture. An awareness of these limitations will allow us to understand better why architects have paid little attention to the interaction of form and energy, and to the bioclimatic approach in contemporary architecture in general. The first limitation stems from the very essence of bioclimatic analysis; en...

  18. Controller Architectures for Switching

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Poulsen, Niels Kjølstad

    2009-01-01

    This paper investigate different controller architectures in connection with controller switching. The controller switching is derived by using the Youla-Jabr-Bongiorno-Kucera (YJBK) parameterization. A number of different architectures for the implementation of the YJBK parameterization are...... described and applied in connection with controller switching. An architecture that does not include inversion of the coprime factors is introduced. This architecture will make controller switching particular simple....

  19. School of Architecture + Design establishes Virginia Tech architecture publications

    OpenAIRE

    Chadwick, Heather Riley

    2007-01-01

    Virginia Tech's School of Architecture + Design, in the College of Architecture and Urban Studies, with the initiative of Markus Breitschmid, assistant professor of architecture, has established Virginia Tech Architecture Publications.

  20. Rapid method for fetal brain fixation.

    OpenAIRE

    Nicholls, J. M.

    1988-01-01

    A quicker alternative to the standard removal and fixation of brain tissue was sought. Whole fetal brains were fixed in situ using a mercuric based fixative. The subarachnoid space was perfused overnight with Heidenhain's Susa fixative. The following day the brains were removed from the cranium in the standard manner. After storage for three days in Susa's fixative the brain was sliced and processed, with excellent preservation of gross and microscopic architecture. The cost is only marginall...

  1. Optimal Trajectories of Brain State Transitions

    OpenAIRE

    Gu, Shi; Betzel, Richard F.; Cieslak, Matthew; Delio, Philip R; Grafton, Scott T; Pasqualetti, Fabio; Danielle S Bassett

    2016-01-01

    The complexity of neural dynamics stems in part from the complexity of the underlying anatomy. Yet how the organization of white matter architecture constrains how the brain transitions from one cognitive state to another remains unknown. Here we address this question from a computational perspective by defining a brain state as a pattern of activity across brain regions. Drawing on recent advances in network control theory, we model the underlying mechanisms of brain state transitions as eli...

  2. Knowledge crash and knowledge management

    OpenAIRE

    Ermine, Jean-Louis

    2010-01-01

    This article, by including the problem of “Knowledge Crash” in the more general framework of “Knowledge Management”, enlarges the concepts of knowledge, generation and knowledge transfer. It proposes a global approach, starting from a strategic analysis of a knowledge capital and ending in the implementation of socio-technical devices for inter-generational knowledge transfer.

  3. Architectural Knitted Surfaces

    DEFF Research Database (Denmark)

    Mossé, Aurélie

    2010-01-01

    WGSN reports from the Architectural Knitted Surfaces workshop recently held at ShenkarCollege of Engineering and Design, Tel Aviv, which offered a cutting-edge insight into interactive knitted surfaces. With the increasing role of smart textiles in architecture, the Architectural Knitted Surfaces...

  4. Brain herniation

    Science.gov (United States)

    ... herniation; Uncal herniation; Subfalcine herniation; Tonsillar herniation; Herniation - brain ... Brain herniation occurs when something inside the skull produces pressure that moves brain tissues. This is most ...

  5. As We May Think and Be: Brain-computer interfaces to expand the substrate of mind

    Directory of Open Access Journals (Sweden)

    Mijail Demian Serruya

    2015-04-01

    Full Text Available Over a half-century ago, the scientist Vannevar Bush explored the conundrum of how to tap the exponentially rising sea of human knowledge for the betterment of humanity. In his description of a hypothetical electronic library he dubbed the memex, he anticipated internet search and online encyclopedias (Bush, 1945. By blurring the boundary between brain and computer, brain-computer interfaces (BCI could lead to more efficient use of electronic resources (Schalk, 2008. We could expand the substrate of the mind itself rather than merely interfacing it to external computers. Components of brain-computer interfaces could be re-arranged to create brain-brain interfaces, or tightly interconnected links between a person’s brain and ectopic neural modules. Such modules – whether sitting in a bubbling Petri dish, rendered in reciprocally linked integrated circuits, or implanted in our belly – would mark the first step on to a path of breaking out of the limitations imposed by our phylogenetic past Novel BCI architectures could generate novel abilities to navigate and access information that might speed translational science efforts and push the boundaries of human knowledge in an unprecedented manner.

  6. The application of graph theoretical analysis to complex networks in the brain.

    Science.gov (United States)

    Reijneveld, Jaap C; Ponten, Sophie C; Berendse, Henk W; Stam, Cornelis J

    2007-11-01

    Considering the brain as a complex network of interacting dynamical systems offers new insights into higher level brain processes such as memory, planning, and abstract reasoning as well as various types of brain pathophysiology. This viewpoint provides the opportunity to apply new insights in network sciences, such as the discovery of small world and scale free networks, to data on anatomical and functional connectivity in the brain. In this review we start with some background knowledge on the history and recent advances in network theories in general. We emphasize the correlation between the structural properties of networks and the dynamics of these networks. We subsequently demonstrate through evidence from computational studies, in vivo experiments, and functional MRI, EEG and MEG studies in humans, that both the functional and anatomical connectivity of the healthy brain have many features of a small world network, but only to a limited extent of a scale free network. The small world structure of neural networks is hypothesized to reflect an optimal configuration associated with rapid synchronization and information transfer, minimal wiring costs, resilience to certain types of damage, as well as a balance between local processing and global integration. Eventually, we review the current knowledge on the effects of focal and diffuse brain disease on neural network characteristics, and demonstrate increasing evidence that both cognitive and psychiatric disturbances, as well as risk of epileptic seizures, are correlated with (changes in) functional network architectural features. PMID:17900977

  7. World Ships - Architectures & Feasibility Revisited

    Science.gov (United States)

    Hein, A. M.; Pak, M.; Putz, D.; Buhler, C.; Reiss, P.

    A world ship is a concept for manned interstellar flight. It is a huge, self-contained and self-sustained interstellar vehicle. It travels at a fraction of a per cent of the speed of light and needs several centuries to reach its target star system. The well- known world ship concept by Alan Bond and Anthony Martin was intended to show its principal feasibility. However, several important issues haven't been addressed so far: the relationship between crew size and robustness of knowledge transfer, reliability, and alternative mission architectures. This paper addresses these gaps. Furthermore, it gives an update on target star system choice, and develops possible mission architectures. The derived conclusions are: a large population size leads to robust knowledge transfer and cultural adaptation. These processes can be improved by new technologies. World ship reliability depends on the availability of an automatic repair system, as in the case of the Daedalus probe. Star systems with habitable planets are probably farther away than systems with enough resources to construct space colonies. Therefore, missions to habitable planets have longer trip times and have a higher risk of mission failure. On the other hand, the risk of constructing colonies is higher than to establish an initial settlement on a habitable planet. Mission architectures with precursor probes have the potential to significantly reduce trip and colonization risk without being significantly more costly than architectures without. In summary world ships remain an interesting concept, although they require a space colony-based civilization within our own solar system before becoming feasible.

  8. Vital architecture, slow momentum policy

    DEFF Research Database (Denmark)

    Braae, Ellen Marie

    2010-01-01

    A reflection on the relation between Danish landscape architecture policy and the statements made through current landscape architectural project.......A reflection on the relation between Danish landscape architecture policy and the statements made through current landscape architectural project....

  9. The effects of stress on brain and adrenal stem cells.

    Science.gov (United States)

    de Celis, M F R; Bornstein, S R; Androutsellis-Theotokis, A; Andoniadou, C L; Licinio, J; Wong, M-L; Ehrhart-Bornstein, M

    2016-05-01

    The brain and adrenal are critical control centers that maintain body homeostasis under basal and stress conditions, and orchestrate the body's response to stress. It is noteworthy that patients with stress-related disorders exhibit increased vulnerability to mental illness, even years after the stress experience, which is able to generate long-term changes in the brain's architecture and function. High levels of glucocorticoids produced by the adrenal cortex of the stressed subject reduce neurogenesis, which contributes to the development of depression. In support of the brain-adrenal connection in stress, many (but not all) depressed patients have alterations in the components of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis, with enlarged adrenal cortex and increased glucocorticoid levels. Other psychiatric disorders, such as post-traumatic stress disorder, bipolar disorder and depression, are also associated with abnormalities in hippocampal volume and hippocampal function. In addition, hippocampal lesions impair the regulation of the LHPA axis in stress response. Our knowledge of the functional connection between stress, brain function and adrenal has been further expanded by two recent, independent papers that elucidate the effects of stress on brain and adrenal stem cells, showing similarities in the way that the progenitor populations of these organs behave under stress, and shedding more light into the potential cellular and molecular mechanisms involved in the adaptation of tissues to stress. PMID:26809844

  10. Knowledge intensive natural language generation with revision

    OpenAIRE

    Cline, Ben E.

    1994-01-01

    Traditional natural language generation systems use a pipelined architecture. Two problems with this architecture are poor task decomposition and the lack of interaction between conceptual and stylistic decisions making. A revision architecture operating in a knowledge intensive environment is proposed as a means to deal with these two problems. In a revision system. text is produced and refined iteratively. A text production cycle consists of two steps. First, the text generator...

  11. Role of expression techniques in interior architecture education

    OpenAIRE

    Özker, Serpil

    2014-01-01

    The Interior Architecture education is examined based on "sketching and presentation" within the framework of "design" by looking into the application patterns, materials used, education, processes and results of these two methods and by providing relevant examples. In the study discusses the knowledge of design, universities providing education, interior architecture presentation process, perspective and focuses on the role of expression techniques in the interior Architecture education. In ...

  12. Open Source Software: How Can Design Metrics Facilitate Architecture Recovery?

    OpenAIRE

    Constantinou, Eleni; Kakarontzas, George; Stamelos, Ioannis

    2011-01-01

    Modern software development methodologies include reuse of open source code. Reuse can be facilitated by architectural knowledge of the software, not necessarily provided in the documentation of open source software. The effort required to comprehend the system's source code and discover its architecture can be considered a major drawback in reuse. In a recent study we examined the correlations between design metrics and classes' architecture layer. In this paper, we apply our methodology in ...

  13. Brain morphometry and the neurobiology of levodopa-induced dyskinesias: current knowledge and future potential for translational pre-clinical neuroimaging studies.

    Directory of Open Access Journals (Sweden)

    Clare eFinlay

    2014-06-01

    Full Text Available Dopamine replacement therapy in the form of levodopa results in a significant proportion of patients with Parkinson's disease (PD developing debilitating dyskinesia. This significantly complicates further treatment and negatively impacts patient quality of life. A greater understanding of the neurobiological mechanisms underlying levodopa-induced dyskinesia (LID is therefore crucial to develop new treatments to prevent or mitigate LID. Such investigations in humans are largely confined to assessment of neurochemical and cerebrovascular blood flow changes using positron emission tomography (PET and functional magnetic resonance imaging (fMRI. However, recent evidence suggests that LID is associated with specific morphological changes in the frontal cortex and midbrain, detectable by structural MRI and voxel-based morphometry (VBM. Current human neuroimaging methods however lack sufficient resolution to reveal the biological mechanism driving these morphological changes at the cellular level. In contrast, there is a wealth of literature from well-established rodent models of LID documenting detailed post-mortem cellular and molecular measurements. The combination therefore of advanced neuroimaging methods and rodent LID models offers an exciting opportunity to bridge these currently disparate areas of research. To highlight this opportunity, in this mini-review, we provide an overview of the current clinical evidence for morphological changes in the brain associated with LID and identify potential cellular mechanisms as suggested from human and animal studies. We then suggest a framework for combining small animal MRI imaging with rodent models of LID, which may provide important mechanistic insights into the neurobiology of LID.

  14. Software architecture evolution

    DEFF Research Database (Denmark)

    Barais, Olivier; Le Meur, Anne-Francoise; Duchien, Laurence;

    2008-01-01

    Software architectures must frequently evolve to cope with changing requirements, and this evolution often implies integrating new concerns. Unfortunately, when the new concerns are crosscutting, existing architecture description languages provide little or no support for this kind of evolution....... The software architect must modify multiple elements of the architecture manually, which risks introducing inconsistencies. This chapter provides an overview, comparison and detailed treatment of the various state-of-the-art approaches to describing and evolving software architectures. Furthermore, we...... discuss one particular framework named Tran SAT, which addresses the above problems of software architecture evolution. Tran SAT provides a new element in the software architecture descriptions language, called an architectural aspect, for describing new concerns and their integration into an existing...

  15. Integrating planning and learning: the prodigy architecture

    OpenAIRE

    Veloso, Manuela; Carbonel, Jaime; PÉREZ, Alicia; Borrajo, Daniel; Fink, Eugene; Blythe, Jim

    1995-01-01

    Planning is a complex reasoning task that is well suited for the study of improving performance and knowledge by learning, i.e. by accumulation and interpretation of planning experience. PRODIGY is an architecture that integrates planning with multiple learning mechanisms. Learning occurs at the planner’s decision points and integration in PRODIGY is achieved via mutually interpretable knowledge structures. This article describes the PRODIGY planner, briefly reports on several learning module...

  16. A Novel Architecture for Collaborative Environments

    OpenAIRE

    Sahar Saberi; Mehdi N. Fesharaki

    2012-01-01

    A novel architecture, called Cognitive Social Knowledge Grid, is introduced as a solution for collaborative environments. The CSKG performs information and knowledge operations through collaboration of agents and services in a service-oriented context. Its services and mechanisms have been described and relationship models of its components and services have been presented using UML. Utilizing capabilities of social network services, user profiles information, social characteristics of human ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... Brain Imaging Using brain imaging technologies such as magnetic resonance imaging (MRI), which uses magnetic fields to take pictures of the brain's structure, studies show that brain growth in children with autism ...

  18. Materials Driven Architectural Design and Representation

    DEFF Research Database (Denmark)

    Kruse Aagaard, Anders

    2015-01-01

    often quite technical and oriented towards the field of engineering. Often cost, efficiency, optimisation and specific functional properties are the driving forces in material research. While this is extremely relevant in relation to new building strategies, material research can potentially also play......This paper aims to outline a framework for a deeper connection between experimentally obtained material knowledge and architectural design. While materials and architecture in the process of realisation are tightly connected, architectural design and representation are often distanced from the...... material domain in which the construction eventually will happen. In many cases, it can seem that materials play the role of a selection of building blocks from which a determined architectural vision or representation are tried to be build. Research in materials, materials behaviour and new materials are...

  19. Module Architecture for in Situ Space Laboratories

    Science.gov (United States)

    Sherwood, Brent

    2010-01-01

    The paper analyzes internal outfitting architectures for space exploration laboratory modules. ISS laboratory architecture is examined as a baseline for comparison; applicable insights are derived. Laboratory functional programs are defined for seven planet-surface knowledge domains. Necessary and value-added departures from the ISS architecture standard are defined, and three sectional interior architecture options are assessed for practicality and potential performance. Contemporary guidelines for terrestrial analytical laboratory design are found to be applicable to the in-space functional program. Densepacked racks of system equipment, and high module volume packing ratios, should not be assumed as the default solution for exploration laboratories whose primary activities include un-scriptable investigations and experimentation on the system equipment itself.

  20. Evolution of brain elaboration.

    Science.gov (United States)

    Farris, Sarah M

    2015-12-19

    Large, complex brains have evolved independently in several lineages of protostomes and deuterostomes. Sensory centres in the brain increase in size and complexity in proportion to the importance of a particular sensory modality, yet often share circuit architecture because of constraints in processing sensory inputs. The selective pressures driving enlargement of higher, integrative brain centres has been more difficult to determine, and may differ across taxa. The capacity for flexible, innovative behaviours, including learning and memory and other cognitive abilities, is commonly observed in animals with large higher brain centres. Other factors, such as social grouping and interaction, appear to be important in a more limited range of taxa, while the importance of spatial learning may be a common feature in insects with large higher brain centres. Despite differences in the exact behaviours under selection, evolutionary increases in brain size tend to derive from common modifications in development and generate common architectural features, even when comparing widely divergent groups such as vertebrates and insects. These similarities may in part be influenced by the deep homology of the brains of all Bilateria, in which shared patterns of developmental gene expression give rise to positionally, and perhaps functionally, homologous domains. Other shared modifications of development appear to be the result of homoplasy, such as the repeated, independent expansion of neuroblast numbers through changes in genes regulating cell division. The common features of large brains in so many groups of animals suggest that given their common ancestry, a limited set of mechanisms exist for increasing structural and functional diversity, resulting in many instances of homoplasy in bilaterian nervous systems. PMID:26554044

  1. Frances: A Tool for Understanding Computer Architecture and Assembly Language

    Science.gov (United States)

    Sondag, Tyler; Pokorny, Kian L.; Rajan, Hridesh

    2012-01-01

    Students in all areas of computing require knowledge of the computing device including software implementation at the machine level. Several courses in computer science curricula address these low-level details such as computer architecture and assembly languages. For such courses, there are advantages to studying real architectures instead of…

  2. Geometric Computing for Freeform Architecture

    KAUST Repository

    Wallner, J.

    2011-06-03

    Geometric computing has recently found a new field of applications, namely the various geometric problems which lie at the heart of rationalization and construction-aware design processes of freeform architecture. We report on our work in this area, dealing with meshes with planar faces and meshes which allow multilayer constructions (which is related to discrete surfaces and their curvatures), triangles meshes with circle-packing properties (which is related to conformal uniformization), and with the paneling problem. We emphasize the combination of numerical optimization and geometric knowledge.

  3. Knowledge management

    OpenAIRE

    Lubojacký, Roman

    2012-01-01

    Knowledge management is a way to effectively manage corporate knowledge. Goal of the thesis is to analyze tasks and ways of knowledge management and technological means to support it and test chosen software tools for creation of knowledge base of business terms. First part of the work is dealing with analysis of knowledge management, technics and tools, which are used and technologies for its support. Second part is focused on testing tools for creation of business terms knowledge base for n...

  4. Meta-tool support for knowledge acquisition

    International Nuclear Information System (INIS)

    Knowledge acquisition is a major bottleneck in expert system development. Specialized, or domain-oriented, knowledge acquisition tools can provide efficient support in restricted domains. However, the principal drawback with specialized knowledge acquisition tools is that the tool cost per expert system developed is typically high. Meta-level environments is an approach to support knowledge engineers in developing such knowledge acquisition tools. Meta-tools, i.e. tools for creating knowledge acquisition tools, can be used to specify and automatically generate knowledge acquisition tools for single domains and even single applications. This thesis presents an abstract architecture approach to the specification of knowledge acquisition tools. In this framework knowledge acquisition tools can be specified according to an abstract model of the target tool architecture. DOTS is a meta-tool that supports the abstract-architecture specification scheme. Knowledge engineers can use DOTS to specify and generate domain-oriented knowledge acquisition tools that can be used by domain experts directly. Two implementations of knowledge acquisition tools for different domains are presented in this thesis. These tools are representatives of knowledge acquisition tools that are desirable to generate form meta-tools. One of them was hand-crafted and specialized to the domain of protein purification planning. The other emerged form an evaluation of DOTS by developing a knowledge acquisition tool in a different domain (troubleshooting laboratory equipment). Results from this evaluation are also reported. (144 refs.) (au)

  5. Landscape Architectural Design as Scientific Inquiry?

    NARCIS (Netherlands)

    Lenzholzer, S.

    2011-01-01

    This presentation discusses ‘landscape architectural design as scientific inquiry’ and exemplifies this with the description of a design process within climate-responsive design leading to new design knowledge. ‘Research and design’ are issues that need increasing attention within landscape architec

  6. Printing in three dimensions: Architectural designers manual

    NARCIS (Netherlands)

    Costa, S.; Mirtsopoulos, I.; Papathanasiou, I.

    2014-01-01

    This "designers' manual" is made during the TIDO-course AR0531 Innovation and Sutainability This guide has been written for architecture students with no or limited knowledge on 3D printing with the purpose of providing them with useful information prior to actually printing. This manual is separa

  7. Developing a New Framework for Integration and Teaching of Computer Aided Architectural Design (CAAD) in Nigerian Schools of Architecture

    Science.gov (United States)

    Uwakonye, Obioha; Alagbe, Oluwole; Oluwatayo, Adedapo; Alagbe, Taiye; Alalade, Gbenga

    2015-01-01

    As a result of globalization of digital technology, intellectual discourse on what constitutes the basic body of architectural knowledge to be imparted to future professionals has been on the increase. This digital revolution has brought to the fore the need to review the already overloaded architectural education curriculum of Nigerian schools of…

  8. The Role of Research in Landscape Architecture Practice

    OpenAIRE

    Chen, Zheng

    2013-01-01

    The profession of landscape architecture has not managed to sufficiently build a  body of solid knowledge through research, which weakens the profession in terms of justifying its practice. In order to investigate why the profession has not built its knowledge-base sufficiently, this dissertation collected first-hand empirical data on the use and need of research in current landscape architecture practice, as well as the perceptions about research among landscape architects. Four questions we...

  9. Knowledge Sharing is Knowledge Creation

    DEFF Research Database (Denmark)

    Greve, Linda

    2015-01-01

    Knowledge sharing and knowledge transfer are important to knowledge communication. However when groups of knowledge workers engage in knowledge communication activities, it easily turns into mere mechanical information processing despite other ambitions. This article relates literature of knowledge...... communication and knowledge creation to an intervention study in a large Danish food production company. For some time a specific group of employees uttered a wish for knowledge sharing, but it never really happened. The group was observed and submitted to metaphor analysis as well as analysis of co...... reducing complexity and dividing knowledge into to dichotomies or hierarchies, knowledge workers should be enabled to use different strategies for knowledge sharing, -transfer and –creation depending on the task and the nature of the knowledge. However if the ambition is to have a strategy for sharing...

  10. Architecture and Stages

    DEFF Research Database (Denmark)

    Kiib, Hans

    2009-01-01

    future. But this is not enough. The agenda is to develop architectural spaces, where social interaction and learning are enhanced by art and fun. How can we develop new architectural designs in our inner cities and waterfronts where eventscapes, learning labs and temporal use are merged with everyday......Architecture and Art as Fuel New development zones for shopping and entertainment and space for festivals inside the city CAN be coupled with art and architecture and become ‘open minded' public domains based on cultural exchange and mutual learning. This type of space could be labelled as...... "experiencescape" - a space between tourism, culture, learning and economy. Strategies related to these challenges involve new architectural concepts and art as ‘engines' for a change. New expressive architecture and old industrial buildings are often combined into hybrid narratives, linking the past with the...

  11. Digital Architecture Planning Model

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna Helene [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Al Rashdan, Ahmad Yahya Mohammad [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Bly, Aaron Douglas [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Rice, Brandon Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Fitzgerald, Kirk [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS); Wilson, Keith Leon [Idaho National Lab. (INL), Idaho Falls, ID (United States). Light Water Reactor Sustainability Program (LWRS)

    2016-03-01

    As part of the U.S. Department of Energy’s Light Water Reactor Sustainability Program, the Digital Architecture (DA) Project focuses on providing a model that nuclear utilities can refer to when planning deployment of advanced technologies. The digital architecture planning model (DAPM) is the methodology for mapping power plant operational and support activities into a DA that unifies all data sources needed by the utilities to operate their plants. The DA is defined as a collection of information technology capabilities needed to support and integrate a wide spectrum of real-time digital capabilities for performance improvements of nuclear power plants. DA can be thought of as integration of the separate instrumentation and control and information systems already in place in nuclear power plants, which are brought together for the purpose of creating new levels of automation in plant work activities. A major objective in DAPM development was to survey all key areas that needed to be reviewed in order for a utility to make knowledgeable decisions regarding needs and plans to implement a DA at the plant. The development was done in two steps. First, researchers surveyed the nuclear industry in order to learn their near-term plans for adopting new advanced capabilities and implementing a network (i.e., wireless and wire) infrastructure throughout the plant, including the power block. Secondly, a literature review covering regulatory documents, industry standards, and technical research reports and articles was conducted. The objective of the review was to identify key areas to be covered by the DAPM, which included the following: 1. The need for a DA and its benefits to the plant 2. Resources required to implement the DA 3. Challenges that need to be addressed and resolved to implement the DA 4. Roles and responsibilities of the DA implementation plan. The DAPM was developed based on results from the survey and the literature review. Model development, including

  12. Knowledge Management.

    Science.gov (United States)

    1999

    The first of the four papers in this symposium, "Knowledge Management and Knowledge Dissemination" (Wim J. Nijhof), presents two case studies exploring the strategies companies use in sharing and disseminating knowledge and expertise among employees. "A Theory of Knowledge Management" (Richard J. Torraco), develops a conceptual framework for…

  13. Knowledge Management

    CERN Document Server

    Gerami, Mohsen

    2010-01-01

    This paper discusses the important process of knowledge and its management, and differences between tacit and explicit knowledge and understanding the culture as a key issue for the successful implementation of knowledge management, in addition to, this paper is concerned with the four-stage model for the evolution of information technology (IT) support for knowledge management in law firms.

  14. Architecture humanitarian emergencies

    DEFF Research Database (Denmark)

    Gomez-Guillamon, Maria; Eskemose Andersen, Jørgen; Contreras, Jorge Lobos;

    2013-01-01

    Introduced by scientific articles conserning architecture and human rights in light of cultures, emergencies, social equality and sustainability, democracy, economy, artistic development and science into architecture. Concluding in definition of needs for new roles, processes and education of...... architecture. Followed by articles focusing on interdisciplinary research and design of emergency shelters as well as educational environments. Finally concretized in 35 studies from international workshops arranged globally on and by different architect schools: Royal Danish Academy of Fine Arts in Denmark...

  15. Discovery Food - Culinary Architecture

    OpenAIRE

    Buettner-Graefenhain, Christine

    2005-01-01

    What keeps places unique in times of globalization? If information, goods, food, architecture are the same everywhere, what`s the difference between places? What are people identifying with? Eating habits are a main factor of cultural identification. How can architecture contribute to these feelings of belonging, self awareness and joy? How can it teach something about the place and the people living there? What if a new kind of culinary architecture can help opening people`s e...

  16. An Architecture for Autonomy

    OpenAIRE

    Alami, Rachid; Chatila, Raja; Fleury, Sara; Ghallab, Malik; Ingrand, Félix

    1998-01-01

    International audience An autonomous robot offers a challenging and ideal field for the study of intelligent architectures. Autonomy within a rational behavior could be evaluated by the robot's effectiveness and robustness in carrying out tasks in different and ill-known environments_ It raises major requirements on the control architecture. Furthermore, a robot as a programmable machine brings up other architectural needs, such as the ease and quality of its speci_cation and programming. ...

  17. Architecture Criticism Blindfolded

    OpenAIRE

    Ann Heylighen; Jasmien Herssens; Hubert Froyen

    2009-01-01

    The paper reports on a recent Belgian initiative targeting architectural practice through the professional press. Architecture critics were invited to revisit an exemplary public building while being blindfolded and guided by persons who are visually impaired. Afterwards, they were asked to report on this visit in an article for an architectural magazine. The initiative aimed at drawing the attention of the critics—and, by extension, the readers of their articles—to the need for accessibil...

  18. The Leadership Brain for Dummies

    CERN Document Server

    Sprenger, Marilee B

    2010-01-01

    Discover how scientific knowledge of the brain can make you a better leader. Based upon the latest breakthroughs in neuroscience and advances in brain-based education, Leadership Brain For Dummies gives you the edge to influence, lead, and transform any team or organization. Drawing concrete connections between the growing scientific knowledge of the brain and leadership, this book gives you the skills to assess your strengths and weaknesses as a leader, adopt a style of leadership that suits your characteristics, determine the learning styles of individual employees, and conduct training sess

  19. Urban Knowledge Arena

    Directory of Open Access Journals (Sweden)

    Karel Schmeidler

    2008-01-01

    Full Text Available COST Action C20 – Urban Knowledge Arena is research programme supported by European Co-operation in the Field of Scientific and Technical Research. It is co-ordinated by COST Office and European Science Foundation. The main objective of this Action is to explore and develop a European Arena for cross boundary, integrated knowledge and Know-how on complex urban problems, which is termed Urban Knowledge Arena. The COST Domain Transport and Urban Development aims at fostering international research networking activities of scientist and experts dealing with transport systems and infrastructures, spatial planning, urban land use and development, urban design, architecture and design and civil engineering issues. The focus is on multi and interdisciplinary approaches and the aim is to cover both basic and applied research activities and their changeovers that are relevant to policy and decision making processes. A significant concern is devoted to activities exploring new research needs and developments.

  20. Architecture of Network Systems

    CERN Document Server

    Serpanos, Dimitrios

    2011-01-01

    Network systems require technical skills in computer architecture, design methodologies, algorithm design, and networking. Architecture of Network Systems explains the practice and methodologies that will allow you to solve a broad range of problems in system design, including problems related to security, quality of service, performance, manageability, and more. Leading researchers Dimitrios Serpanos and Tilman Wolf develop architectures for all network sub-systems, bridging the gap between operation and VLSI. Discussing the major challenges in the design of networks and the architectures tha

  1. IT Architecture For Dummies

    CERN Document Server

    Hausman, Kalani Kirk

    2010-01-01

    A solid introduction to the practices, plans, and skills required for developing a smart system architecture. Information architecture combines IT skills with business skills in order to align the IT structure of an organization with the mission, goals, and objectives of its business. This friendly introduction to IT architecture walks you through the myriad issues and complex decisions that many organizations face when setting up IT systems to work in sync with business procedures. Veteran IT professional and author Kirk Hausman explains the business value behind IT architecture and provides

  2. Grid Architecture 2

    Energy Technology Data Exchange (ETDEWEB)

    Taft, Jeffrey D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-01-01

    The report describes work done on Grid Architecture under the auspices of the Department of Electricity Office of Electricity Delivery and Reliability in 2015. As described in the first Grid Architecture report, the primary purpose of this work is to provide stakeholder insight about grid issues so as to enable superior decision making on their part. Doing this requires the creation of various work products, including oft-times complex diagrams, analyses, and explanations. This report provides architectural insights into several important grid topics and also describes work done to advance the science of Grid Architecture as well.

  3. Open Source Software: How Can Design Metrics Facilitate Architecture Recovery?

    CERN Document Server

    Constantinou, Eleni; Stamelos, Ioannis

    2011-01-01

    Modern software development methodologies include reuse of open source code. Reuse can be facilitated by architectural knowledge of the software, not necessarily provided in the documentation of open source software. The effort required to comprehend the system's source code and discover its architecture can be considered a major drawback in reuse. In a recent study we examined the correlations between design metrics and classes' architecture layer. In this paper, we apply our methodology in more open source projects to verify the applicability of our method. Keywords: system understanding; program comprehension; object-oriented; reuse; architecture layer; design metrics;

  4. A Novel Architecture for Collaborative Environments

    Directory of Open Access Journals (Sweden)

    Sahar Saberi

    2012-03-01

    Full Text Available A novel architecture, called Cognitive Social Knowledge Grid, is introduced as a solution for collaborative environments. The CSKG performs information and knowledge operations through collaboration of agents and services in a service-oriented context. Its services and mechanisms have been described and relationship models of its components and services have been presented using UML. Utilizing capabilities of social network services, user profiles information, social characteristics of human and operational environment, CSKG collaboration management services form communities to perform an activity submitted by a user or an application program. We believe that our proposed architecture supports collaborative knowledge societies. Ultimately, CSKG performance and execution capabilities in large-scale collaboration networks have been evaluated. Furthermore, community formation based on user profiles similarities and social parameters like trust and commitment is argued using weighted cosine similarity function.

  5. Knowledge Sharing

    DEFF Research Database (Denmark)

    Holdt Christensen, Peter

    The concept of knowledge management has, indeed, become a buzzword that every single organization is expected to practice and live by. Knowledge management is about managing the organization's knowledge for the common good of the organization -but practicing knowledge management is not as simple as...... that. This article focuses on knowledge sharing as the process seeking to reduce the resources spent on reinventing the wheel.The article introduces the concept of time sensitiveness; i.e. that knowledge is either urgently needed, or not that urgently needed. Furthermore, knowledge sharing is...... considered as either a push or pull system. Four strategies for sharing knowledge - help, post-it, manuals and meeting, and advice are introduced. Each strategy requires different channels for sharing knowledge. An empirical analysis in a production facility highlights how the strategies can be practiced....

  6. Knowledge Technologies

    CERN Document Server

    Milton, Nick

    2008-01-01

    Several technologies are emerging that provide new ways to capture, store, present and use knowledge. This book is the first to provide a comprehensive introduction to five of the most important of these technologies: Knowledge Engineering, Knowledge Based Engineering, Knowledge Webs, Ontologies and Semantic Webs. For each of these, answers are given to a number of key questions (What is it? How does it operate? How is a system developed? What can it be used for? What tools are available? What are the main issues?). The book is aimed at students, researchers and practitioners interested in Knowledge Management, Artificial Intelligence, Design Engineering and Web Technologies. During the 1990s, Nick worked at the University of Nottingham on the application of AI techniques to knowledge management and on various knowledge acquisition projects to develop expert systems for military applications. In 1999, he joined Epistemics where he worked on numerous knowledge projects and helped establish knowledge management...

  7. Prefrontal Cortex Motivated Cognitive Architecture for Multiple Robots

    OpenAIRE

    Mishra, Amit Kumar; Kumar, Abhishek; Deb, Dipankar

    2014-01-01

    In this paper, we introduce a cerebral cortex inspired architecture for robots in which we have mapped hierarchical cortical representation of human brain to logic flow and decision making process. Our work focuses on the two major features of human cognitive process, viz. the perception action cycle and its hierarchical organization, and the decision making process. To prove the effectiveness of our proposed method, we incorporated this architecture in our robot which we named as Cognitive I...

  8. Brain Tumors

    Science.gov (United States)

    A brain tumor is a growth of abnormal cells in the tissues of the brain. Brain tumors can be benign, with no cancer cells, or ... cancer cells that grow quickly. Some are primary brain tumors, which start in the brain. Others are metastatic, ...

  9. Brain Basics

    Medline Plus

    Full Text Available ... Basics will introduce you to some of this science, such as: How the brain develops How genes and the environment affect the brain The basic structure of the brain How different parts of the brain communicate and work with each other How changes in the brain ...

  10. Brain Tumors

    Science.gov (United States)

    A brain tumor is a growth of abnormal cells in the tissues of the brain. Brain tumors can be benign, with no cancer cells, ... cancer cells that grow quickly. Some are primary brain tumors, which start in the brain. Others are ...

  11. Brain Fingerprinting

    Directory of Open Access Journals (Sweden)

    ravi kumar

    2012-12-01

    Full Text Available Brain Fingerprinting is a scientific technique to determine whether or not specific information is stored in an individual's brain by measuring a electrical brain wave response to Word, phrases, or picture that are presented on computer screen. Brain Fingerprinting is a controversial forensic science technique that uses electroencephalograph y (EEG to determine whether specific information is stored in a subject's brain

  12. "Tacit Knowledge" versus "Explicit Knowledge"

    DEFF Research Database (Denmark)

    Sanchez, Ron

    2004-01-01

    This paper explains two fundamental approaches to knowledge management. The tacitknowledge approach emphasizes understanding the kinds of knowledge that individualsin an organization have, moving people to transfer knowledge within an organization,and managing key individuals as knowledge creator...... organization. The relative advantages and disadvantages of bothapproaches to knowledge management are summarized. A synthesis of tacit andknowledge management approaches is recommended to create a hybrid design for theknowledge management practices in a given organization....

  13. Formalization and visualization of domain-specific software architectures

    Science.gov (United States)

    Bailor, Paul D.; Luginbuhl, David R.; Robinson, John S.

    1992-01-01

    This paper describes a domain-specific software design system based on the concepts of software architectures engineering and domain-specific models and languages. In this system, software architectures are used as high level abstractions to formulate a domain-specific software design. The software architecture serves as a framework for composing architectural fragments (e.g., domain objects, system components, and hardware interfaces) that make up the knowledge (or model) base for solving a problem in a particular application area. A corresponding software design is generated by analyzing and describing a system in the context of the software architecture. While the software architecture serves as the framework for the design, this concept is insufficient by itself for supplying the additional details required for a specific design. Additional domain knowledge is still needed to instantiate components of the architecture and develop optimized algorithms for the problem domain. One possible way to obtain the additional details is through the use of domain-specific languages. Thus, the general concept of a software architecture and the specific design details provided by domain-specific languages are combined to create what can be termed a domain-specific software architecture (DSSA).

  14. Knowledge management

    DEFF Research Database (Denmark)

    Foss, Nicolai Juul; Mahnke, Volker

    2003-01-01

    Knowledge management has emerged as a very successful organization practice and has beenextensively treated in a large body of academic work. Surprisingly, however, organizationaleconomics (i.e., transaction cost economics, agency theory, team theory and property rightstheory) has played no role in...... the development of knowledge management. We argue thatorganizational economics insights can further the theory and practice of knowledge managementin several ways. Specifically, we apply notions of contracting, team production,complementaries, hold-up, etc. to knowledge management issues (i.......e., creating and integrationknowledge, rewarding knowledge workers, etc.) , and derive refutable implications that are novelto the knowledge management field from our discussion....

  15. Knowledge Management

    International Nuclear Information System (INIS)

    In 2001, SCK-CEN decided to adopt and implement a practical knowledge management approach. Knowledge management activities were identified within the organisation and a co-ordinated approach to knowledge management was applied. Such an approach requires an efficient reuse of recorded knowledge and an effective transfer of the available knowledge. This approach ensures an added value to our research work and guarantees the long-term preservation of the institutional memory. Principle results and future developments regarding knowledge management at SCK-CEN are summarised

  16. Neural simulations on multi-core architectures

    Directory of Open Access Journals (Sweden)

    Hubert Eichner

    2009-07-01

    Full Text Available Neuroscience is witnessing increasing knowledge about the anatomy and electrophysiological properties of neurons and their connectivity, leading to an ever increasing computational complexity of neural simulations. At the same time, a rather radical change in personal computer technology emerges with the establishment of multi-cores: high-density, explicitly parallel processor architectures for both high performance as well as standard desktop computers. This work introduces strategies for the parallelization of biophysically realistic neural simulations based on the compartmental modeling technique and results of such an implementation, with a strong focus on multi-core architectures and automation, i. e. user-transparent load balancing.

  17. Advanced control architecture for autonomous vehicles

    Science.gov (United States)

    Maurer, Markus; Dickmanns, Ernst D.

    1997-06-01

    An advanced control architecture for autonomous vehicles is presented. The hierarchical architecture consists of four levels: a vehicle level, a control level, a rule-based level and a knowledge-based level. A special focus is on forms of internal representation, which have to be chosen adequately for each level. The control scheme is applied to VaMP, a Mercedes passenger car which autonomously performs missions on German freeways. VaMP perceives the environment with its sense of vision and conventional sensors. It controls its actuators for locomotion and attention focusing. Modules for perception, cognition and action are discussed.

  18. Clinical document architecture.

    Science.gov (United States)

    Heitmann, Kai

    2003-01-01

    The Clinical Document Architecture (CDA), a standard developed by the Health Level Seven organisation (HL7), is an ANSI approved document architecture for exchange of clinical information using XML. A CDA document is comprised of a header with associated vocabularies and a body containing the structural clinical information. PMID:15061557

  19. Software Architecture Evolution

    Science.gov (United States)

    Barnes, Jeffrey M.

    2013-01-01

    Many software systems eventually undergo changes to their basic architectural structure. Such changes may be prompted by new feature requests, new quality attribute requirements, changing technology, or other reasons. Whatever the causes, architecture evolution is commonplace in real-world software projects. Today's software architects, however,…

  20. Towards a Media Architecture

    DEFF Research Database (Denmark)

    Ebsen, Tobias

    2010-01-01

    This text explores the concept of media architecture as a phenomenon of visual culture that describes the use of screen-technology in new spatial configurations in practices of architecture and art. I shall argue that this phenomenon is not necessarily a revolutionary new approach, but rather...

  1. Workflow automation architecture standard

    Energy Technology Data Exchange (ETDEWEB)

    Moshofsky, R.P.; Rohen, W.T. [Boeing Computer Services Co., Richland, WA (United States)

    1994-11-14

    This document presents an architectural standard for application of workflow automation technology. The standard includes a functional architecture, process for developing an automated workflow system for a work group, functional and collateral specifications for workflow automation, and results of a proof of concept prototype.

  2. Architecture or Sculpture?

    DEFF Research Database (Denmark)

    Baumeister, Ruth

    Jørn Utzon´s museum design for Asger Jorn´s collection in Silkeborg contextualized in the postwar context of an organic architecture.......Jørn Utzon´s museum design for Asger Jorn´s collection in Silkeborg contextualized in the postwar context of an organic architecture....

  3. Architecture and energy

    DEFF Research Database (Denmark)

    Marsh, Rob; Lauring, Michael

    2011-01-01

    Traditional low-energy architecture has not necessarily led to reduced energy consumption. A paradigm shift is proposed promoting pluralistic energy-saving strategies.......Traditional low-energy architecture has not necessarily led to reduced energy consumption. A paradigm shift is proposed promoting pluralistic energy-saving strategies....

  4. A catalog of architectural primitives for modeling architectural patterns

    NARCIS (Netherlands)

    Zdun, Uwe; Avgeriou, Paris

    2008-01-01

    Architectural patterns are a fundamental aspect of the architecting process and subsequently the architectural documentation. Unfortunately, there is only poor support for modeling architectural patterns for two reasons. First, patterns describe recurring design solutions and hence do not directly m

  5. Knowledge Management

    International Nuclear Information System (INIS)

    Knowledge management is an evolving subject area based on two notions: - That knowledge is a fundamental aspect of effective organizational performance; - That specific steps need to be actively taken to promote knowledge creation and use. Two common approaches to knowledge management that are often used in combination include: - Knowledge management focused on the capture of explicit knowledge and sharing this via technology; - Knowledge management focused on managing tacit knowledge without necessarily making it explicit, and creating new knowledge as well as sharing existing knowledge. In the context of human resources development, knowledge management is strongly tied to strategy and is activity oriented. Properly applied knowledge management improves organizational efficiency and productivity through reducing process times, introducing technology to assist finding relevant information and instituting techniques to remedy poor quality outputs. Knowledge management also promotes innovations, which can result from initiatives such as developing social networks for knowledge exchange, providing leadership to encourage risk taking and capturing the lessons learned from past activities. Both of these benefits require openness to change and a drive for continual improvement. Other benefits of knowledge management include improved decision making, retaining organizational memory and organizational learning, as well as improving morale. Knowledge management can be used on its own or in collaboration with other management disciplines and tools to establish an environment that will enable the organization to realize these benefits. Summarizing the effective management of nuclear knowledge includes ensuring the continued availability of qualified personnel. As the nuclear workforce ages and retires, and with support uncertain for university programmes in nuclear science and engineering, this issue has become critical to ensuring safety and security, encouraging innovation

  6. Architecture as Ars Combinatoria

    Directory of Open Access Journals (Sweden)

    Francesco Cacciatore

    2015-11-01

    Full Text Available Architecture today, no longer reflects the limits of experimentation and innovation. An extremely low-tech art whose field of possibilities consists of choosing and using that which has already been done in the past. It is because of this that the key skill a designer should have is the ability to recognize the complexity in forms around them: cities have the widest programming opportunities for architecture, in the two-way relationship that is established from the city that takes form in architecture and an architecture that finds its place in the contemporary city. Thus, architecture has its foundation in hospitality, an element that differentiates it significantly from the design.

  7. Product Architecture Modularity Strategies

    DEFF Research Database (Denmark)

    Mikkola, Juliana Hsuan

    2003-01-01

    The focus of this paper is to integrate various perspectives on product architecture modularity into a general framework, and also to propose a way to measure the degree of modularization embedded in product architectures. Various trade-offs between modular and integral product architectures and...... how components and interfaces influence the degree of modularization are considered. In order to gain a better understanding of product architecture modularity as a strategy, a theoretical framework and propositions are drawn from various academic literature sources. Based on the literature review......, the following key elements of product architecture are identified: components (standard and new-to-the-firm), interfaces (standardization and specification), degree of coupling, and substitutability. A mathematical function, termed modularization function, is introduced to measure the degree of...

  8. Geometrical objects architecture and the mathematical sciences 1400-1800

    CERN Document Server

    2014-01-01

    This volume explores the mathematical character of architectural practice in diverse pre- and early modern contexts. It takes an explicitly interdisciplinary approach, which unites scholarship in early modern architecture with recent work in the history of science, in particular, on the role of practice in the scientific revolution. As a contribution to architectural history, the volume contextualizes design and construction in terms of contemporary mathematical knowledge, attendant forms of mathematical practice, and relevant social distinctions between the mathematical professions. As a contribution to the history of science, the volume presents a series of micro-historical studies that highlight issues of process, materiality, and knowledge production in specific, situated, practical contexts. Our approach sees the designer’s studio, the stone-yard, the drawing floor, and construction site not merely as places where the architectural object takes shape, but where mathematical knowledge itself is depl...

  9. ARCHITECTURE IN THE ISLAMIC CIVILIZATION: MUSLIM BUILDING OR ISLAMIC ARCHITECTURE

    OpenAIRE

    Ayat Ali Yassin; Dr. Nangkula Utaberta

    2012-01-01

    The main problem of the theory in the arena of islamic architecture is affected by some of its Westernthoughts, and stereotyping the islamic architecture according to Western thoughts; this leads to the breakdownof the foundations in the islamic architecture. It is a myth that islamic architecture is subjected to theinfluence from foreign architectures. This paper will highlight the dialectical concept of islamic architecture ormuslim buildings and the areas of recognition in islamic architec...

  10. Analysis of Architecture Pattern Usage in Legacy System Architecture Documentation

    OpenAIRE

    Harrison, Neil B.; Avgeriou, Paris

    2008-01-01

    Architecture patterns are an important tool in architectural design. However, while many architecture patterns have been identified, there is little in-depth understanding of their actual use in software architectures. For instance, there is no overview of how many patterns are used per system or which patterns are the most common or most important for particular domains. In addition, little is known of how architecture patterns may interact with each other. We studied architecture documentat...

  11. Accessible Knowledge - Knowledge on Accessibility

    DEFF Research Database (Denmark)

    Kirkeby, Inge Mette

    2015-01-01

    Although serious efforts are made internationally and nationally, it is a slow process to make our physical environment accessible. In the actual design process, architects play a major role. But what kinds of knowledge, including research-based knowledge, do practicing architects make use of when...... designing accessible environments? The answer to the question is crucially important since it affects how knowledge is distributed and how accessibility can be ensured. In order to get first-hand knowledge about the design process and the sources from which they gain knowledge, 11 qualitative interviews...... were conducted with architects with experience of designing for accessibility. The analysis draws on two theoretical distinctions. The first is research-based knowledge versus knowledge used by architects. The second is context-independent knowledge versus context-dependent knowledge. The practitioners...

  12. Brain Basics

    Medline Plus

    Full Text Available ... The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are the basic working unit of the ... distant nerve cells (via axons) to form brain circuits. These circuits control specific body functions such as ...

  13. Brain Basics

    Medline Plus

    Full Text Available ... than ever before. Brain Imaging Using brain imaging technologies such as magnetic resonance imaging (MRI), which uses magnetic fields to take pictures of the brain's structure, studies ...

  14. Brain Basics

    Medline Plus

    Full Text Available ... Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... others live with symptoms of mental illness every day. They can be moderate, or serious and cause ...

  15. Brain Basics

    Medline Plus

    Full Text Available ... helps Sarah to better cope with her feelings. Brain Research Modern research tools and techniques are giving scientists ... the treatment for a person's specific conditions. Such brain research help increase the understanding of how the brain ...

  16. Brain Basics

    Medline Plus

    Full Text Available ... little dopamine or problems using dopamine in the thinking and feeling regions of the brain may play ... than ever before. Brain Imaging Using brain imaging technologies such as magnetic resonance imaging (MRI), which uses ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... as depression. The Growing Brain Inside the Brain: Neurons & Neural Circuits Neurons are the basic working unit of the brain ... specialized for the function of conducting messages. A neuron has three basic parts: Cell body which includes ...

  18. Brain Malformations

    Science.gov (United States)

    Most brain malformations begin long before a baby is born. Something damages the developing nervous system or causes it ... medicines, infections, or radiation during pregnancy interferes with brain development. Parts of the brain may be missing, ...

  19. Brain Basics

    Medline Plus

    Full Text Available ... brain's structure, studies show that brain growth in children with autism appears to peak early. And as ... grow there are differences in brain development in children who develop bipolar disorder than children who do ...

  20. Brain Basics

    Medline Plus

    Full Text Available ... Basics will introduce you to some of this science, such as: How the brain develops How genes and the environment affect the brain The basic structure of the brain How different parts of ...

  1. Brain Basics

    Medline Plus

    Full Text Available ... understanding of the brain than ever before. Brain Imaging Using brain imaging technologies such as magnetic resonance imaging (MRI), which uses magnetic fields to take pictures ...

  2. Brain Basics

    Medline Plus

    Full Text Available ... science, such as: How the brain develops How genes and the environment affect the brain The basic ... that with brain development in people mental disorders. Genes and environmental cues both help to direct this ...

  3. Brain surgery

    Science.gov (United States)

    Craniotomy; Surgery - brain; Neurosurgery; Craniectomy; Stereotactic craniotomy; Stereotactic brain biopsy; Endoscopic craniotomy ... cut depends on where the problem in the brain is located. The surgeon creates a hole in ...

  4. Knowledge Technologies

    OpenAIRE

    Milton, Nick

    2008-01-01

    Several technologies are emerging that provide new ways to capture, store, present and use knowledge. This book is the first to provide a comprehensive introduction to five of the most important of these technologies: Knowledge Engineering, Knowledge Based Engineering, Knowledge Webs, Ontologies and Semantic Webs. For each of these, answers are given to a number of key questions (What is it? How does it operate? How is a system developed? What can it be used for? What tools are available? Wha...

  5. Knowledge management

    OpenAIRE

    Nádvorník, Pavel

    2011-01-01

    The main goal of this thesis is to describe implementation of the information system that will support knowledge management using KM-Beat-it methodology in Helpdesk department of the Wincor Nixdorf, Ltd. company. Due to lack of knowledge management principles usage this system will support procedures and processes of knowledge management. Setup and implementation of this system was performed using and combining of two methodologies, methodology for knowledge management implementation KM-Beat-...

  6. Brain mapping

    OpenAIRE

    Blaž Koritnik

    2004-01-01

    Cartography of the brain ("brain mapping") aims to represent the complexities of the working brain in an understandable and usable way. There are four crucial steps in brain mapping: (1) acquiring data about brain structure and function, (2) transformation of data into a common reference, (3) visualization and interpretation of results, and (4) databasing and archiving. Electrophysiological and functional imaging methods provide information about function of the human brain. A prere...

  7. Architecture in the Experience City

    DEFF Research Database (Denmark)

    Kiib, Hans

    narratives related to historical buildings and architectural heritage; another group tries to embed new performative technologies in expressive architectural representation. The article provides a theoretical framework for the analysis of the political rationales of these projects and for the architectural...

  8. Evolution of contemporary museum architecture

    OpenAIRE

    Bilous, Yulia

    2013-01-01

    This article deals with the development of museum architecture from the formation of the classic building architecture to the establishment of the contemporary museum architecture. Changes in the museum building architecture and displaying principles have been analysed. The 19th century was defined by the emergence of a vast number of museums serving through present as examples of the contemporary museum architecture. New styles are tried in the museum architecture alo...

  9. Hybrid architecture: object, landscape, infrastructure

    OpenAIRE

    Pinto de Freitas, Rita

    2011-01-01

    The concept of "hybrid architecture" developed in this study considers hybrid all architecture that is at once object, landscape and infrastructure. Hybrid architecture, pushed by the fact that it concentrates in a single architectural intervention a triple object-, landscape- and infrastructure-related nature, generates architectural answers with very specific features, and its study achieves following goals: 1: Clarify the term hybrid related to architectural intervention; 2: Tran...

  10. Business Capabilities Centric Enterprise Architecture

    OpenAIRE

    Barroero, Thiago; Motta, Gianmario; Pignatelli, Giovanni

    2010-01-01

    In the field of Enterprise Architecture, The Open Group Architecture Framework (TOGAF) is a well known framework, that links Business Architecture, Data Architecture, Application Architecture, Technology. A key concept within Business Architecture domain is Business Capabilities, that are delivered by Business Component (BC). A BC is a business unit that encompasses a coherent set of activities, supported by assets including people, processes and technology. Current TOGAF version recognizes t...

  11. Data-Centric Enterprise Architecture

    OpenAIRE

    Zeinab Rajabi; Maryam Nooraei Abade

    2012-01-01

    Enterprises choose Enterprise Architecture (EA) solution, in order to overcome dynamic business challenges and in coordinate various enterprise elements. In this article, a solution is suggested for the Enterprise Architecture development. The solution focuses on architecture data in the Enterprise Architecture development process. Data-centric architecture approach is preferred product-centric architecture approach. We suggest using Enterprise Ontology (EO) as context for collecting architec...

  12. Knowledge spaces

    CERN Document Server

    Doignon, Jean-Paul

    1999-01-01

    Knowledge spaces offer a rigorous mathematical foundation for various practical systems of knowledge assessment. An example is offered by the ALEKS system (Assessment and LEarning in Knowledge Spaces), a software for the assessment of mathematical knowledge. From a mathematical standpoint, knowledge spaces generalize partially ordered sets. They are investigated both from a combinatorial and a stochastic viewpoint. The results are applied to real and simulated data. The book gives a systematic presentation of research and extends the results to new situations. It is of interest to mathematically oriented readers in education, computer science and combinatorics at research and graduate levels. The text contains numerous examples and exercises and an extensive bibliography.

  13. Development of a computerized handbook of architectural plans: Ontwikkeling van een gecomputeriseerd handboek van architectonische plattegronden

    OpenAIRE

    Koutamanis, A.

    1990-01-01

    The dissertation investigates an approach to the development of visual / spatial computer representations for architectural purposes through the development of the computerized handbook of architectural plans (chap), a knowledge-based computer system capable of recognizing the metric properties of architectural plans. This investigation can be summarized as an introduction of computer vision to the computerization of architectural representations: chap represents an attempt to automate recogn...

  14. The NAi Effect: Museological Institutions and the Construction of Architectural Discourse

    OpenAIRE

    Figueiredo, Sergio Miguel

    2014-01-01

    While historically, institutions shaping architectural discourse have been primarily academic, recently, architecture museums and institutes have emerged as increasingly influential platforms in furthering architectural debate. As nexus of architectural knowledge, these institutions have become particularly operative in contemporary society, primarily by involving a wide audience. By not only engaging the concerns of a broad audience, but allowing a broad audience to engage with the stakes, p...

  15. Knowledge Management

    Science.gov (United States)

    Shariq, Syed Z.; Kutler, Paul (Technical Monitor)

    1997-01-01

    The emergence of rapidly expanding technologies for distribution and dissemination of information and knowledge has brought to focus the opportunities for development of knowledge-based networks, knowledge dissemination and knowledge management technologies and their potential applications for enhancing productivity of knowledge work. The challenging and complex problems of the future can be best addressed by developing the knowledge management as a new discipline based on an integrative synthesis of hard and soft sciences. A knowledge management professional society can provide a framework for catalyzing the development of proposed synthesis as well as serve as a focal point for coordination of professional activities in the strategic areas of education, research and technology development. Preliminary concepts for the development of the knowledge management discipline and the professional society are explored. Within this context of knowledge management discipline and the professional society, potential opportunities for application of information technologies for more effectively delivering or transferring information and knowledge (i.e., resulting from the NASA's Mission to Planet Earth) for the development of policy options in critical areas of national and global importance (i.e., policy decisions in economic and environmental areas) can be explored, particularly for those policy areas where a global collaborative knowledge network is likely to be critical to the acceptance of the policies.

  16. Knowledge Services for Distributed Service Integration

    OpenAIRE

    Chen, Liming; Cox, Simon J.; Goble, Carole; Roberts, A; Shadbolt, Nigel; Smart, Paul; Tao, Feng

    2002-01-01

    Key Objectives: Introduce a service-oriented approach for the provision of knowledge-based support for distributed computing, develop a generic knowledge service architecture to realise this approach, and apply this approach to design search and optimisation in order to enhance the design development process.

  17. KNOWLEDGE MANAGEMENT PRINCIPLES

    Directory of Open Access Journals (Sweden)

    Marlize Breedt

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Business drivers such as digitisation, globalisation, customer intimacy and the emergence of the Information Age initiate the need to manage the organisation's knowledge asset. Knowledge management aims at leveraging this explicit and tacit knowledge asset to the collective benefit of the organisation by developing an infrastructure to facilitate the knowledge process and by making information readily available. The implementation of such an initiative requires integration of the strategic, process, human resource, and technology architecture components as the company's competitive advantage depends on the quality of the organisation's knowledge asset and successful exploitation of it.

    AFRIKAANSE OPSOMMING: Veranderingsdrywers soos digitalisering, globalisering, klienteverhoudings en die ontstaan van die inligtingsera inisieer die behoefte om organisasiekennishulpbronne te bestuur. Kennisbestuur het ten doel om die eksplisiete en nie-eksplisiete kennishulpbron tot die gesamentlike voordeel van die organisasie aan te wend deur 'n infrastruktuur daar te stel om die kennisproses te fasiliteer en inligting beskikbaar te stel. Die implementering van 'n kennisbestuursinisiatief vereis integrasie van die strategiese-, proses-, menslikehulpbron-, en tegnologieargitektuur komponente ten einde die kompeterende voordeel van die organisasie te behou. Onderliggend tot die sukses is die vermoe en kwaliteit van die organisasie se kennishulpbronne.

  18. On Detailing in Contemporary Architecture

    DEFF Research Database (Denmark)

    Kristensen, Claus; Kirkegaard, Poul Henning

    Details in architecture have a significant influence on how architecture is experienced. One can touch the materials and analyse the detailing - thus details give valuable information about the architectural scheme as a whole. The absence of perceptual stimulation like details and materiality...... / tactility can blur the meaning of the architecture and turn it into an empty statement. The present paper will outline detailing in contemporary architecture and discuss the issue with respect to architectural quality. Architectural cases considered as sublime piece of architecture will be presented and...... discussed with respect to the meaning of detailing....

  19. Integrated Data Assimilation Architecture Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Integrated Data Assimilation Architecture (IDAA) is a middleware architecture that facilitates the incorporation of heterogeneous sensing and control devices...

  20. Avionics Architecture for Exploration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Avionics Architectures for Exploration Project team will develop a system level environment and architecture that will accommodate equipment from multiple...

  1. Computer architecture technology trends

    CERN Document Server

    1991-01-01

    Please note this is a Short Discount publication. This year's edition of Computer Architecture Technology Trends analyses the trends which are taking place in the architecture of computing systems today. Due to the sheer number of different applications to which computers are being applied, there seems no end to the different adoptions which proliferate. There are, however, some underlying trends which appear. Decision makers should be aware of these trends when specifying architectures, particularly for future applications. This report is fully revised and updated and provides insight in

  2. Architecture, energy and climate

    DEFF Research Database (Denmark)

    Lauring, Michael

    2010-01-01

    Architecture has always had to relate to climatic conditions while providing shelter from the sun, the rain, the winds or the cold. This is a main purpose of buildings: To establish an indoor climate different from the outdoor. In the Nordic countries fuels for heating buildings has been a vital...... cases been to search for traditional and pre-industrialized ways of building and settlement. The idea of this theme number is not to flee from modern life and approaches, but instead to face modern conditions relevant in achieving sustainable urban development and sustainable architecture, the only...... truly modern architecture that exists....

  3. Architecture for Verifiable Software

    Science.gov (United States)

    Reinholtz, William; Dvorak, Daniel

    2005-01-01

    Verifiable MDS Architecture (VMA) is a software architecture that facilitates the construction of highly verifiable flight software for NASA s Mission Data System (MDS), especially for smaller missions subject to cost constraints. More specifically, the purpose served by VMA is to facilitate aggressive verification and validation of flight software while imposing a minimum of constraints on overall functionality. VMA exploits the state-based architecture of the MDS and partitions verification issues into elements susceptible to independent verification and validation, in such a manner that scaling issues are minimized, so that relatively large software systems can be aggressively verified in a cost-effective manner.

  4. Statistics of genome architecture

    International Nuclear Information System (INIS)

    The main statistical distributions applicable to the analysis of genome architecture and genome tracks are briefly discussed and critically assessed. Although the observed features in distributions of element lengths can be equally well fitted by the different statistical approximations, the interpretation of observed regularities may strongly depend on the chosen scheme. We discuss the possible evolution scenarios and describe the main characteristics obtained with different distributions. The expression for the assessment of levels in hierarchical chromatin folding is derived and the quantitative measure of genome architecture inhomogeneity is suggested. This theory provides the ground for the regular statistical study of genome architecture and genome tracks.

  5. Knowledge transfer

    DEFF Research Database (Denmark)

    Andersen, Simon; Hardahl, Nicolai; Hvid, Daniel;

    2012-01-01

    From 2001 to 2007 Arla Foods, one of the largest dairy companies in the world has undergone a major Enterprise Architecture transformation involving organizational and technological changes. While the changes have been successful and the organization is enjoying a period of unprecedented success,...

  6. Knowledge cycle and strategic knowledge within company

    OpenAIRE

    Ovidiu NICOLESCU

    2007-01-01

    In the knowledge-based economy, a company performs a set of activities focused on knowledge: identifying necessary knowledge, buying knowledge, learning, acquiring knowledge, creating knowledge, storing knowledge, sharing knowledge, using knowledge, protection of knowledge, capitalizing knowledge. As a result, a new function emerge: the knowledge function. In the knowledge-based companies, not every knowledge has the same impact. The analysis of the actual situations in the most developed an...

  7. Mixed Reality Architecture: a dynamic architectural topology

    OpenAIRE

    Schnädelbach, H.; A Penn; Steadman, P.

    2007-01-01

    Architecture can be shown to structure patterns of co-presence and in turn to be structured itself by the rules and norms of the society present within it. This two-way relationship exists in a surprisingly stable framework, as fundamental changes to buildings are slow and costly. At the same time, change within organisations is increasingly rapid and buildings are used to accommodate some of that change. This adaptation can be supported by the use of telecommunication technolo...

  8. Robot Electronics Architecture

    Science.gov (United States)

    Garrett, Michael; Magnone, Lee; Aghazarian, Hrand; Baumgartner, Eric; Kennedy, Brett

    2008-01-01

    An electronics architecture has been developed to enable the rapid construction and testing of prototypes of robotic systems. This architecture is designed to be a research vehicle of great stability, reliability, and versatility. A system according to this architecture can easily be reconfigured (including expanded or contracted) to satisfy a variety of needs with respect to input, output, processing of data, sensing, actuation, and power. The architecture affords a variety of expandable input/output options that enable ready integration of instruments, actuators, sensors, and other devices as independent modular units. The separation of different electrical functions onto independent circuit boards facilitates the development of corresponding simple and modular software interfaces. As a result, both hardware and software can be made to expand or contract in modular fashion while expending a minimum of time and effort.

  9. DSP Architecture Design Essentials

    CERN Document Server

    Marković, Dejan

    2012-01-01

    In DSP Architecture Design Essentials, authors Dejan Marković and Robert W. Brodersen cover a key subject for the successful realization of DSP algorithms for communications, multimedia, and healthcare applications. The book addresses the need for DSP architecture design that maps advanced DSP algorithms to hardware in the most power- and area-efficient way. The key feature of this text is a design methodology based on a high-level design model that leads to hardware implementation with minimum power and area. The methodology includes algorithm-level considerations such as automated word-length reduction and intrinsic data properties that can be leveraged to reduce hardware complexity. From a high-level data-flow graph model, an architecture exploration methodology based on linear programming is used to create an array of architectural solutions tailored to the underlying hardware technology. The book is supplemented with online material: bibliography, design examples, CAD tutorials and custom software.

  10. Greek architecture now

    DEFF Research Database (Denmark)

    Skousbøll, Karin Merete

    2006-01-01

    With the author's Scandinavian viewpoint the aim of this book has been an investigation into contemporary Greek architecture and at the same time providing an understanding for its essential characteristics based on the historic, cultural heritage of Hellas....

  11. Analyzing architecture articles

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In the present study, we express the quality, function, and characteristics of architecture to help people comprehensively understand what architecture is. We also reveal the problems and conflict found in population, land, water resources, pollution, energy, and the organization systems in construction. China’s economy is transforming. We should focus on the cities, architectural environment, energy conservation, emission-reduction, and low-carbon output that will result in successful green development. We should macroscopically and microscopically analyze the development, from the natural environment to the artificial environment; from the relationship between human beings and nature to the combination of social ecology in cities, and farmlands. We must learn to develop and control them harmoniously and scientifically to provide a foundation for the methods used in architecture research.

  12. Adaptive Architectural Envelope

    DEFF Research Database (Denmark)

    Foged, Isak Worre; Kirkegaard, Poul Henning

    2010-01-01

    Recent years have seen an increasing variety of applications of adaptive architectural structures for improvement of structural performance by recognizing changes in their environments and loads, adapting to meet goals, and using past events to improve future performance or maintain serviceability....... The general scopes of this paper are to develop a new adaptive kinetic architectural structure, particularly a reconfigurable architectural structure which can transform body shape from planar geometries to hyper-surfaces using different control strategies, i.e. a transformation into more than one or...... two different shape alternatives. The adaptive structure is a proposal for a responsive building envelope which is an idea of a first level operational framework for present and future investigations towards performance based responsive architectures through a set of responsive typologies. A mock- up...

  13. Architectural Competition and BIM

    DEFF Research Database (Denmark)

    Sørensen, Nils Lykke; Frandsen, Anne Kathrine; Øien, Turid Borgestrand

    2015-01-01

    on architecturalcompetitions, a series of interviews was conducted with building clients as well as architects, focusing on the impact of the above-mentioned changes within the building sector on architectural competitions as an institution. In the interviews, ICT and notleast BIM was a recurring...... clients, architects and client consultants) and the applied technologies (competition forms, ICT tools, directives) in architectural competitions in a theoretical actor-network perspective. The diverging understandings of the role of BIM are demonstrating one of many negotiations in progress in the...... network of architectural competitions. BIM is transformed from an inscription device visually representing the competition proposals to form an actant that challenges the very concept of architectural competition. The objective of the paper is to contribute to theunderstanding of BIM used in the kind of...

  14. An OER Architecture Framework: Need and Design

    Directory of Open Access Journals (Sweden)

    Pankaj Khanna

    2013-03-01

    Full Text Available This paper describes an open educational resources (OER architecture framework that would bring significant improvements in a well-structured and systematic way to the educational practices of distance education institutions of India. The OER architecture framework is articulated with six dimensions: pedagogical, technological, managerial, academic, financial, and ethical. These dimensions are structured with the component areas of relevance: IT infrastructure services, management support systems, open content development and maintenance, online teaching-learning, and learner assessment and evaluation of the OER architecture framework. An OER knowledge and information base, including a web portal, is proposed in the form of a series of knowledge repositories. This system would not only streamline the delivery of distance education but also would enhance the quality of distance learning through the development of high quality e-content, instructional processes, course/programme content development, IT infrastructure, and network systems. Thus the proposed OER architecture framework when implemented in the distance education system (DES of India would improve the quality of distance education and also increase its accessibility in a well-organised and structured way.

  15. Analysis of Architecture Pattern Usage in Legacy System Architecture Documentation

    NARCIS (Netherlands)

    Harrison, Neil B.; Avgeriou, Paris

    2008-01-01

    Architecture patterns are an important tool in architectural design. However, while many architecture patterns have been identified, there is little in-depth understanding of their actual use in software architectures. For instance, there is no overview of how many patterns are used per system or wh

  16. Brain Basics

    Medline Plus

    Full Text Available ... in Real Life Brain Research Glossary Brain Basics (PDF, 10 pages) Introduction Watch the Brain Basics video ... early brain development, and may also assist in learning and memory. ... rise to disabilities or diseases. neural circuit —A network of neurons ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... than ever before. Brain Imaging Using brain imaging technologies such as magnetic resonance imaging (MRI), which uses magnetic fields to take pictures of the brain's structure, studies show that brain growth in children with autism appears to peak early. And as ...

  18. Brain Basics

    Medline Plus

    Full Text Available ... Research Modern research tools and techniques are giving scientists a more detailed understanding of the brain than ever before. Brain Imaging Using brain imaging technologies such as magnetic resonance imaging (MRI), which uses magnetic fields to take pictures of the brain's structure, studies ...

  19. Brain Basics

    Medline Plus

    Full Text Available ... Welcome. Brain Basics provides information on how the brain works, how mental illnesses are disorders of the brain, ... highly developed area at the front of the brain that, in humans, plays a role in executive functions such as ...

  20. Redesigning architecture through photography

    OpenAIRE

    Germen, Murat

    2008-01-01

    Abstract – This paper focuses on the possibility of (re)designing architecture virtually with the help of one of the most important representation tools: Photography. Various digital processes like stitching multiple photos together and mirroring images in image editing software like Photoshop, allow this virtual architecture to take place in virtual environments. Photography can be utilized in the process of ‘constructing’ a new space --that we can call ‘narrative space’-- from an existing s...

  1. Generic Distributed Simulation Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Booker, C.P.

    1999-05-14

    A Generic Distributed Simulation Architecture is described that allows a simulation to be automatically distributed over a heterogeneous network of computers and executed with very little human direction. A prototype Framework is presented that implements the elements of the Architecture and demonstrates the feasibility of the concepts. It provides a basis for a future, improved Framework that will support legacy models. Because the Framework is implemented in Java, it may be installed on almost any modern computer system.

  2. Pushing architectural quality further

    OpenAIRE

    Laverge, Jelle; Van Den Bossche, Nathan; Janssens, Arnold

    2008-01-01

    In this paper, the intentions thriving the implementation of computational modeling of building physics as it is approached in the Architectural engineering courses at Ghent University are discussed. During the bachelor degree, courses focus mainly on integration of basic building physics feasibility in the architectural conceptualization. During the final bachelor year, students program their own simplified 2D models for internal condensation and thermal bridges in a spreadsheet, based on...

  3. Climate and architecture

    DEFF Research Database (Denmark)

    Tind Kristensen, Eva; Friis Møller, Winnie; Rotne, Georg;

    2010-01-01

    Climate and Architecture analyserer klimaets rolle i arkitekturen. Intentionen med bogen er at pege på nogle af de mange muligheder for bygningers klimaregulering, som et mere detaljeret studie af de lokale klimatiske forhold og den stedlige byggeskik tilbyder.......Climate and Architecture analyserer klimaets rolle i arkitekturen. Intentionen med bogen er at pege på nogle af de mange muligheder for bygningers klimaregulering, som et mere detaljeret studie af de lokale klimatiske forhold og den stedlige byggeskik tilbyder....

  4. Digitally-Driven Architecture

    OpenAIRE

    Henriette Bier; Terry Knight

    2014-01-01

    The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While stan...

  5. Models of Architecture

    OpenAIRE

    Pelcat, Maxime; Desnos, Karol; Maggiani, Luca; Liu, Yanzhou; Heulot, Julien; Nezan, Jean-François; Bhattacharyya, Shuvra S.

    2015-01-01

    The current trend in high performance and embedded computing consists of designing increasingly complex heterogeneous hardware architectures with non-uniform communication resources. In order to take hardware and software design decisions, early evaluations of the system non-functional properties are needed. These evaluations of system efficiency require high-level information on both the algorithms and the architecture. In state of the art Model Driven Engineering (MDE) methods, different co...

  6. Aesthetics of sustainable architecture

    OpenAIRE

    Lee, S.

    2011-01-01

    The purpose of this book is to reveal, explore and further the debate on the aesthetic potentials of sustainable architecture and its practice. This book opens a new area of scholarship and discourse in the design and production of sustainable architecture, one that is based in aesthetics. The chapters in this book have been compiled from architects and scholars working in diverse research and practice areas in North America, Europe, the Middle East and Asia. While they approach the subject m...

  7. Governing Knowledge

    OpenAIRE

    Nicolai J Foss; Dana B Minbaeva

    2009-01-01

    SHRM increasingly emphasizes HRM practices as means to build strategic knowledge resources such as superior capabilities. While the knowledge-based view increasingly pays attention to micro-foundations, the SHRM field neglects these and emphasizes collective constructs such as “human capital pools,” “HRM architectures”, etc. As a result, causal links between HRM practices, knowledge and organizational performance are black-boxed. We propose a program for research and identify s...

  8. Brain mapping

    Directory of Open Access Journals (Sweden)

    Blaž Koritnik

    2004-08-01

    Full Text Available Cartography of the brain ("brain mapping" aims to represent the complexities of the working brain in an understandable and usable way. There are four crucial steps in brain mapping: (1 acquiring data about brain structure and function, (2 transformation of data into a common reference, (3 visualization and interpretation of results, and (4 databasing and archiving. Electrophysiological and functional imaging methods provide information about function of the human brain. A prerequisite for multisubject, multidimensional and multimodal mapping is transformation of individual images to match a standard brain template. To produce brain maps, color, contours, and other visual cues are used to differentiate metabolic rates, electrical field potentials, receptor densities, and other attributes of structure or function. Databases are used to organize and archive data records. By relating the maps to cognitive functions and psychological models, brain mapping offers a prerequisite for the understanding of organizational principles of the human brain.

  9. An Object-Oriented Architecture for Intelligent Tutoring Systems. Technical Report No. LSP-3.

    Science.gov (United States)

    Bonar, Jeffrey; And Others

    This technical report describes a generic architecture for building intelligent tutoring systems which is developed around objects that represent the knowledge elements to be taught by the tutor. Each of these knowledge elements, called "bites," inherits both a knowledge organization describing the kind of knowledge represented and tutoring…

  10. Knowledge Economy

    OpenAIRE

    Kerr, Aphra; O'riain, Sean

    2009-01-01

    We examine a number of key questions regarding this knowledge economy. First, we look at the origin of the concept as well as early attempts to define and map the knowledge economy empirically. Second, we examine a variety of perspectives on the socio-spatial organisation of the knowledge economy and approaches which link techno-economic change and social-spatial organisation. Building on a critique of these perspectives, we then go on to develop a view of a knowledge economy that is conteste...

  11. Placing knowledge

    DEFF Research Database (Denmark)

    Adriansen, Hanne Kirstine; Valentin, Karen; Nielsen, Gritt B.

    Internationalisation of higher education is premised by a seeming paradox: On the one hand, academic knowledge strives to be universal in the sense that it claims to produce generalizable, valid and reliable knowledge that can be used, critiqued, and redeveloped by academics from all over the world......; on the other hand, the rationale for strengthening mobility through internationalisation is based on an imagination of the potentials of particular locations (academic institutions). Intrigued by this tension between universality and particularity in academic knowledge production, this paper presents...... for studying what comes to count as e.g. relevant, good, true knowledge, to whom, where and why....

  12. Spatial normalization of brain images and beyond.

    Science.gov (United States)

    Mangin, J-F; Lebenberg, J; Lefranc, S; Labra, N; Auzias, G; Labit, M; Guevara, M; Mohlberg, H; Roca, P; Guevara, P; Dubois, J; Leroy, F; Dehaene-Lambertz, G; Cachia, A; Dickscheid, T; Coulon, O; Poupon, C; Rivière, D; Amunts, K; Sun, Z Y

    2016-10-01

    The deformable atlas paradigm has been at the core of computational anatomy during the last two decades. Spatial normalization is the variant endowing the atlas with a coordinate system used for voxel-based aggregation of images across subjects and studies. This framework has largely contributed to the success of brain mapping. Brain spatial normalization, however, is still ill-posed because of the complexity of the human brain architecture and the lack of architectural landmarks in standard morphological MRI. Multi-atlas strategies have been developed during the last decade to overcome some difficulties in the context of segmentation. A new generation of registration algorithms embedding architectural features inferred for instance from diffusion or functional MRI is on the verge to improve the architectural value of spatial normalization. A better understanding of the architectural meaning of the cortical folding pattern will lead to use some sulci as complementary constraints. Improving the architectural compliance of spatial normalization may impose to relax the diffeomorphic constraint usually underlying atlas warping. A two-level strategy could be designed: in each region, a dictionary of templates of incompatible folding patterns would be collected and matched in a way or another using rare architectural information, while individual subjects would be aligned using diffeomorphisms to the closest template. Manifold learning could help to aggregate subjects according to their morphology. Connectivity-based strategies could emerge as an alternative to deformation-based alignment leading to match the connectomes of the subjects rather than images. PMID:27344104

  13. Neural Simulations on Multi-Core Architectures

    OpenAIRE

    Hubert Eichner; Tobias Klug

    2009-01-01

    Neuroscience is witnessing increasing knowledge about the anatomy and electrophysiological properties of neurons and their connectivity, leading to an ever increasing computational complexity of neural simulations. At the same time, a rather radical change in personal computer technology emerges with the establishment of multi-cores: high-density, explicitly parallel processor architectures for both high performance as well as standard desktop computers. This work introduces strategies for th...

  14. Data Warehouse Architecture for DSS Applciations

    OpenAIRE

    V. J. Anand; Himawan Gunadhi

    1996-01-01

    A data warehouse facilitates the integration of disparate operational databases in an enterprise into a single store. The warehouse then provides knowledge workers with easy access to historical, summarized and other forms of aggregated data. A major flaw in present warehouse architectures is the de-coupling of the warehouse database from its underlying operational databases. This creates two problems: the difficulty in updating the warehouse and the inability to provide users with a drill-do...

  15. Utilizing the Central Courtyard of Traditional Architecture in Modern Architecture

    OpenAIRE

    Javad Samadi

    2014-01-01

    The purpose of this study is utilizing the central courtyard of traditional architecture in modern architecture. Since the nineteenth century, the traditional architecture has been more taken into account. From this time period, the sixties century is significantly important. The studies on the traditional architecture were conducted and followed in this period with the new objective and attitude. Until the early sixties century, most of the studies on the traditional architecture were briefl...

  16. Advances in Brain Research: Implications for Educators

    Science.gov (United States)

    Stickel, Sue A.

    2005-01-01

    Cognitive neuroscience will provide theoretical foundations for areas of educational policy and practice. Educators will benefit from knowledge in the basic sciences related to brain development and function. Brain development begins at birth and the brain remains capable of complex changes throughout the lifespan. Educators will want to be aware…

  17. Learning and Knowledge Depreciation in Professional Services

    OpenAIRE

    Tonya Boone; Ram Ganeshan; Hicks, Robert L.

    2008-01-01

    Organizational knowledge is a critical source of competitive advantage for professional service firms. Learning from experience and sustaining past knowledge are critical to the success of such knowledge-driven firms. We use learning curve theory to evaluate learning and depreciation in professional services. Our results, based on seven years of project data collected from an architectural engineering (A/E) firm, show that (a) professional services exhibit learning curves, (b) there is virtua...

  18. Multimedia Distributed Knowledge Management in MIAKT

    OpenAIRE

    Dupplaw, David; Dasmahapatra, Srinandan; Hu, Bo; Lewis, Paul; Shadbolt, Nigel

    2004-01-01

    Digital media facilitates tight integration of multi-modal information and networking allows this richly textured knowledge to be shared. We present the system we have developed in the MIAKT (Medical Imaging with Advanced Knowledge Technologies) project that provides knowledge management, and facilities for semantic annotations on mammographic images in the context of clinical and histopathological information. This paper also describes the novel generic architecture we have built on semantic...

  19. Brains on video games.

    Science.gov (United States)

    Bavelier, Daphne; Green, C Shawn; Han, Doug Hyun; Renshaw, Perry F; Merzenich, Michael M; Gentile, Douglas A

    2011-12-01

    The popular press is replete with stories about the effects of video and computer games on the brain. Sensationalist headlines claiming that video games 'damage the brain' or 'boost brain power' do not do justice to the complexities and limitations of the studies involved, and create a confusing overall picture about the effects of gaming on the brain. Here, six experts in the field shed light on our current understanding of the positive and negative ways in which playing video games can affect cognition and behaviour, and explain how this knowledge can be harnessed for educational and rehabilitation purposes. As research in this area is still in its early days, the contributors of this Viewpoint also discuss several issues and challenges that should be addressed to move the field forward. PMID:22095065

  20. New Energy Architecture. Myanmar

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-15

    A global transition towards a new energy architecture is under way, driven by countries' need to respond to the changing dynamics of economic growth, environmental sustainability and energy security. The World Economic Forum, in collaboration with Accenture, has created the New Energy Architecture Initiative to address and accelerate this transition. The Initiative supports the development of national strategies and policy frameworks as countries seek to achieve the combined goals of energy security and access, sustainability, and economic growth and development. The World Economic Forum has formed a partnership with the Ministry of Energy of Myanmar to help apply the Initiative's approach to this developing and resource-rich nation. The Asian Development Bank and the World Economic Forum's Project Adviser, Accenture, have collaborated with the Forum on this consultation process, and have been supported by relevant government, industry and civil society stakeholders. The consultation process aims to understand the nation's current energy architecture challenges and provide an overview of a path to a New Energy Architecture through a series of insights. These insights could form the basis for a long-term multistakeholder roadmap to build Myanmar's energy sector in a way that is secure and sustainable, and promotes economic growth as the country makes its democratic transition. While not all recommendations can be implemented in the near term, they do provide options for creating a prioritized roadmap for Myanmar's energy transition. This report is the culmination of a nine-month multistakeholder process investigating Myanmar's energy architecture. Over the course of many visits to the country, the team has conducted numerous interviews, multistakeholder workshops, and learning and data-gathering exercises to ensure a comprehensive range of information and views. The team has also engaged with a variety of stakeholders to better

  1. Time · Space · Architecture

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In the 20th century a Swiss writer wrote a book titled Time, Space and Architecture, in which he discussed the relationship between architecture and the times. Fifty years after that, this paper adopts the same title, hoping to deepen the understanding of the space-time structure in architecture and contribute to the new exploration of architectural forms.

  2. A Cognitive Neural Architecture Able to Learn and Communicate through Natural Language.

    Directory of Open Access Journals (Sweden)

    Bruno Golosio

    Full Text Available Communicative interactions involve a kind of procedural knowledge that is used by the human brain for processing verbal and nonverbal inputs and for language production. Although considerable work has been done on modeling human language abilities, it has been difficult to bring them together to a comprehensive tabula rasa system compatible with current knowledge of how verbal information is processed in the brain. This work presents a cognitive system, entirely based on a large-scale neural architecture, which was developed to shed light on the procedural knowledge involved in language elaboration. The main component of this system is the central executive, which is a supervising system that coordinates the other components of the working memory. In our model, the central executive is a neural network that takes as input the neural activation states of the short-term memory and yields as output mental actions, which control the flow of information among the working memory components through neural gating mechanisms. The proposed system is capable of learning to communicate through natural language starting from tabula rasa, without any a priori knowledge of the structure of phrases, meaning of words, role of the different classes of words, only by interacting with a human through a text-based interface, using an open-ended incremental learning process. It is able to learn nouns, verbs, adjectives, pronouns and other word classes, and to use them in expressive language. The model was validated on a corpus of 1587 input sentences, based on literature on early language assessment, at the level of about 4-years old child, and produced 521 output sentences, expressing a broad range of language processing functionalities.

  3. Quantitative Architectural Analysis: A New Approach to Cortical Mapping

    Science.gov (United States)

    Schleicher, Axel; Morosan, Patricia; Amunts, Katrin; Zilles, Karl

    2009-01-01

    Results from functional imaging studies are often still interpreted using the classical architectonic brain maps of Brodmann and his successors. One obvious weakness in traditional, architectural mapping is the subjective nature of localizing borders between cortical areas by means of a purely visual, microscopical examination of histological…

  4. National Knowledge Commission

    Science.gov (United States)

    Pitroda, Sam

    2007-04-01

    India's National Knowledge Commission (NKC) established by the prime minister is focused on building institutions and infrastructure in Education, Science and Technology, Innovation etc. to meet the challenges of the knowledge economy in the 21st century and increase India's competitive advantage in the global market. India today stands poised to reap the benefits of a rapidly growing economy and a major demographic advantage, with 550 million young people below the age of 25 years, the largest in the world. The NKC is focused on five critical areas of knowledge related to access, concepts, creation, applications and services. This includes a variety of subject areas such as language, translations, libraries, networks, portals, affirmative action, distance learning, intellectual property, Entrepreneurship, application in Agriculture, health, small and medium scale industries, e-governance etc. One of the keys to this effort is to build a national broadband gigabit of networks of 500 nodes to connect universities, Libraries, Laboratories, Hospitals, Agriculture institutions etc. to share resources and collaborate on multidisciplinary activities. This presentation will introduce the NKC, discuss methodology, subject areas, specific recommendation and outline a plan to build knowledge networks and specifics on network architecture, applications, and utilities.

  5. Knowledge Management

    Science.gov (United States)

    Deepak

    2005-01-01

    Knowledge Management (KM) is the process through which organizations generate value from their intellectual and knowledge-based assets. Frequently generating value from such assets means sharing them among employees, divisions and even with other companies in order to develop best practices. This article discusses three basic aspects of…

  6. Data-Centric Enterprise Architecture

    Directory of Open Access Journals (Sweden)

    Zeinab Rajabi

    2012-08-01

    Full Text Available Enterprises choose Enterprise Architecture (EA solution, in order to overcome dynamic business challenges and in coordinate various enterprise elements. In this article, a solution is suggested for the Enterprise Architecture development. The solution focuses on architecture data in the Enterprise Architecture development process. Data-centric architecture approach is preferred product-centric architecture approach. We suggest using Enterprise Ontology (EO as context for collecting architecture data; Enterprise Ontology enhances quality of architecture data and lead to effective architecture results for decision-making. First, Enterprise is modeled using the ontology. Then how collecting Enterprise Architecture data based on the Enterprise Ontology is explained. Finally, the results and advantages of the solution are demonstrated.

  7. KNOWLEDGE MANAGEMENT AND KNOWLEDGE WORKERS

    OpenAIRE

    POPESCU, Dan; Geanina CUCU-CIUHAN,; Iulia CHIVU; Manuela CIUCUREL

    2009-01-01

    The last decade has witnessed an exponential growth of interest in organizational learning and Knowledge Management. This comes as a natural consequence of the ever more widespread understanding of the knowledge-based economy as a revolutionary change in the global economy. The rise of the service economy, the increasingly flow of global information, and the growing recognition of the importance of intellectual capital are turning knowledge into a key critical resource and a source of competi...

  8. Sound knowledge

    DEFF Research Database (Denmark)

    Kauffmann, Lene Teglhus

    The thesis is about the conceptualisation of knowledge associated with ‘evidence’. In the Danish society, there is a proliferating demand for ‘evidence’, which started as the basis of practices in medicine and has spread into social work, education and most policymaking arenas. The aim of the...... research is to investigate what is considered to ‘work as evidence’ in health promotion and how the ‘evidence discourse’ influences social practices in policymaking and in research. From investigating knowledge practices in the field of health promotion, I develop the concept of sound knowledge as...... knowledge based on reflexive practices. I chose ‘health promotion’ as the field for my research as it utilises knowledge produced in several research disciplines, among these both quantitative and qualitative. I mapped out the institutions, actors, events, and documents that constituted the field of health...

  9. Cannabinoids on the Brain

    Directory of Open Access Journals (Sweden)

    Andrew J. Irving

    2002-01-01

    Full Text Available Cannabis has a long history of consumption both for recreational and medicinal uses. Recently there have been significant advances in our understanding of how cannabis and related compounds (cannabinoids affect the brain and this review addresses the current state of knowledge of these effects. Cannabinoids act primarily via two types of receptor, CB1 and CB2, with CB1 receptors mediating most of the central actions of cannabinoids. The presence of a new type of brain cannabinoid receptor is also indicated. Important advances have been made in our understanding of cannabinoid receptor signaling pathways, their modulation of synaptic transmission and plasticity, the cellular targets of cannabinoids in different central nervous system (CNS regions and, in particular, the role of the endogenous brain cannabinoid (endocannabinoid system. Cannabinoids have widespread actions in the brain: in the hippocampus they influence learning and memory; in the basal ganglia they modulate locomotor activity and reward pathways; in the hypothalamus they have a role in the control of appetite. Cannabinoids may also be protective against neurodegeneration and brain damage and exhibit anticonvulsant activity. Some of the analgesic effects of cannabinoids also appear to involve sites within the brain. These advances in our understanding of the actions of cannabinoids and the brain endocannabinoid system have led to important new insights into neuronal function which are likely to result in the development of new therapeutic strategies for the treatment of a number of key CNS disorders.

  10. Educating ecological architecture – ecological educational architecture

    OpenAIRE

    Costa Santos, Sandra; Klein, Gerald; Despang, Martin

    2010-01-01

    “Sustainability,” being the buzzword of the 21st century, is particularly challenging to the current generation, now in their early teens, which grew up with a childhood of lackadaisical use of fossil energy. This generation, which will soon be leading the world, has been inappropriately labeled the “generation me” and is expected to prove its successful transitioning into “generation p[ostfossil].” If the young emerging architectural professionals choose, they can be the mission group in hel...

  11. Virtual architecture: reconstructing architecture through photography

    OpenAIRE

    Germen, Murat

    2007-01-01

    The concept of construction in architectural design process is a temporary action that exists for a while and transforms itself into another product; i.e. the final building to be inhabited. Construction site can be taken as a podium where a play-to-remain-incomplete is being staged. The incompleteness causes us to dream, due to the fact that a complete building loses its narrative potential as it informs us about all the necessary pieces that constitute the whole: There is no puzzle to solve...

  12. Knowledge transfer - Acquiring implicit knowledge

    International Nuclear Information System (INIS)

    Many organisations have recognised the problem of experts taking home a huge amount of specific knowledge, which they have gathered in their department, when they leave. The successor is capable only of acquiring explicit expertise because implicit experiences are not documented and therefore no more available. That is why we have started this pilot study in order to try to conserve the above mentioned tacit and implicit knowledge and to make it available to other colleagues. Using a semi-standardised interview we elicit tacit knowledge from the expert and summarise it in a report. This interview-guideline forms the basis of in-depth investigation for implicit knowledge. (author)

  13. Perceived benefits from enterprise architecture

    OpenAIRE

    Plessius, Henk; Steenbergen, Marlies van; Slot, Raymond

    2014-01-01

    Enterprise Architecture has been developed in order to optimize the alignment between business needs and the (rapidly changing) possibilities of information technology. But do organizations indeed benefit from the application of Enterprise Architecture according to those who are in any way involved in architecture? To answer this question, a model has been developed (the Enterprise Architecture Value Framework) to organize the benefits of Enterprise Architecture. Based on this model, a survey...

  14. The architecture of information architecture, interaction design and the patterning of digital information

    CERN Document Server

    Dade-Robertson, Martyn

    2011-01-01

    This book looks at relationships between the organization of physical objects in space and the organization of ideas. Historical, philosophical, psychological and architectural knowledge are united to develop an understanding of the relationship between information and its representation.Despite its potential to break the mould, digital information has relied on metaphors from a pre-digital era. In particular, architectural ideas have pervaded discussions of digital information, from the urbanization of cyberspace in science fiction, through to the adoption of spatial visualiz

  15. Phenomenology of perception and memorizing contemporary architectural forms

    Directory of Open Access Journals (Sweden)

    Alihodžić Rifat

    2010-01-01

    Full Text Available Perception of an architectural form is not a unilateral act which has been often and unduly identified with mechanicistic captures of a camera. In understanding architectural composition and the way it influences our perception and memory, the knowledge regarding the field of psychology of perception and the analysis of principles of its use in architecture proved to be highly important. Instinctive understanding of perceptual processes and of laws according which our visual apparatus and memory are influenced by the architectural form and space is something that cannot be avoided. These are the operating principles of the so called "ordinary" observer; and this is an important insight for architecture as a visual discipline, which has been often neglected. As a significant addition to intuition and experience, the creative work of architects is supported by the insights on perceptual and cognitive processes which have been revealed by the psychology of perception.

  16. FASHION AND ARCHITECTURE

    Directory of Open Access Journals (Sweden)

    Hatice Harmankaya

    2014-04-01

    Full Text Available Fashion and architecture fields as non-verbal expression languages are affected by social, cultural, economic and historical factors and shaped around creativity. In both disciplines, based on human scales, employed material is brought dimension in the scope of math. Hue, texture, material, rate-ratio, line, form and shape are common design components of both fashion and architecture. Especially it is possible to see the accrued interactions in terms of pattern, form and decoration throughout the history. The aim of this survey is determining the common grounds, similarities, and interactions of clothing and architectural design that cover to protect the human body based on housing instinct. Descriptive method is used in the survey that examines the subject in depth. In the survey, that structural constitutions constructed on human body are studied in both fields in extent of art, status of fashion designers are affected from architecture is examined. New approaches are exhibited by giving examples of clothing designs in accordance with architectural principles.

  17. The Simulation Intranet Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, V.P.; Linebarger, J.M.; Miller, D.J.; Vandewart, R.L.

    1998-12-02

    The Simdarion Infranet (S1) is a term which is being used to dcscribc one element of a multidisciplinary distributed and distance computing initiative known as DisCom2 at Sandia National Laboratory (http ct al. 1998). The Simulation Intranet is an architecture for satisfying Sandia's long term goal of providing an end- to-end set of scrviccs for high fidelity full physics simu- lations in a high performance, distributed, and distance computing environment. The Intranet Architecture group was formed to apply current distributed object technologies to this problcm. For the hardware architec- tures and software models involved with the current simulation process, a CORBA-based architecture is best suited to meet Sandia's needs. This paper presents the initial desi-a and implementation of this Intranct based on a three-tier Network Computing Architecture(NCA). The major parts of the architecture include: the Web Cli- ent, the Business Objects, and Data Persistence.

  18. Grid Approach with Metadata of Messages in Service Oriented Architecture

    OpenAIRE

    Jamal S. M. Khalid; Asif M

    2014-01-01

    Service Orientation Architecture is playing a vital role in the middleware and enterprise organizations through its key design principles and there are many benefits of it as well. Loose Coupling between services is one of its design principles that help system or architecture to maintain its efficiency because services are less dependent on each other. Stopping of one service could not affect other service and system but there is a fact that services have less knowledge of other services tha...

  19. The Architecture and Datasets of Docear's Research Paper Recommender System

    OpenAIRE

    Beel, Joeran; Langer, Stefan; Gipp, Bela; Nürnberger, Andreas

    2014-01-01

    In the past few years, we have developed a research paper recommender system for our reference management software Docear. In this paper, we introduce the architecture of the recommender system and four datasets. The architecture comprises of multiple components, e.g. for crawling PDFs, generating user models, and calculating content-based recommendations. It supports researchers and developers in building their own research paper recommender systems, and is, to the best of our knowledge, the...

  20. Development of a permeability-limited model of the human brain and cerebrospinal fluid (CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data.

    Science.gov (United States)

    Gaohua, Lu; Neuhoff, Sibylle; Johnson, Trevor N; Rostami-Hodjegan, Amin; Jamei, Masoud

    2016-06-01

    A 4-compartment permeability-limited brain (4Brain) model consisting of brain blood, brain mass, cranial and spinal cerebrospinal fluid (CSF) compartments has been developed and incorporated into a whole body physiologically-based pharmacokinetic (PBPK) model within the Simcyp Simulator. The model assumptions, structure, governing equations and system parameters are described. The model in particular considers the anatomy and physiology of the brain and CSF, including CSF secretion, circulation and absorption, as well as the function of various efflux and uptake transporters existing on the blood-brain barrier (BBB) and blood-CSF barrier (BCSFB), together with the known parameter variability. The model performance was verified using in vitro data and clinical observations for paracetamol and phenytoin. The simulated paracetamol spinal CSF concentration is comparable with clinical lumbar CSF data for both intravenous and oral doses. Phenytoin CSF concentration-time profiles in epileptic patients were simulated after accounting for disease-induced over-expression of efflux transporters within the BBB. Various 'what-if' scenarios, involving variation of specific drug and system parameters of the model, demonstrated that the 4Brain model is able to simulate the possible impact of transporter-mediated drug-drug interactions, the lumbar puncture process and the age-dependent change in the CSF turnover rate on the local PK within the brain. PMID:27236639

  1. Brain tumors: Special characters for research and banking

    OpenAIRE

    Majid Kheirollahi; Sepideh Dashti; Zahra Khalaj; Fatemeh Nazemroaia; Parvin Mahzouni

    2015-01-01

    A brain tumor is an intracranial neoplasm within the brain or in the central spinal canal. Primary malignant brain tumors affect about 200,000 people worldwide every year. Brain cells have special characters. Due to the specific properties of brain tumors, including epidemiology, growth, and division, investigation of brain tumors and the interpretation of results is not simple. Research to identify the genetic alterations of human tumors improves our knowledge of tumor biology, genetic inter...

  2. Knowledge Blogging

    DEFF Research Database (Denmark)

    Agerdal-Hjermind, Annette

    The rise of social media and web 2.0 technologies over the last few years has impacted many communication functions. One influence is organizational bloggers as knowledge mediators on government agency practices. The ways in which these organizational bloggers in their roles as experts are able to...... change, facilitate, and enable communication about a broad range of specialized knowledge areas, in a more open interactional institutional communication environment than traditional media typically offer, give rise to a set of new implications as regards the mediation of expert knowledge to the target...

  3. Avionics System Architecture Tool

    Science.gov (United States)

    Chau, Savio; Hall, Ronald; Traylor, marcus; Whitfield, Adrian

    2005-01-01

    Avionics System Architecture Tool (ASAT) is a computer program intended for use during the avionics-system-architecture- design phase of the process of designing a spacecraft for a specific mission. ASAT enables simulation of the dynamics of the command-and-data-handling functions of the spacecraft avionics in the scenarios in which the spacecraft is expected to operate. ASAT is built upon I-Logix Statemate MAGNUM, providing a complement of dynamic system modeling tools, including a graphical user interface (GUI), modeling checking capabilities, and a simulation engine. ASAT augments this with a library of predefined avionics components and additional software to support building and analyzing avionics hardware architectures using these components.

  4. Persian architecture and mathematics

    CERN Document Server

    2012-01-01

    This volulme features eight original papers dedicated to the theme “Persian Architecture and Mathematics,” guest edited by Reza Sarhangi. All papers were approved through a rigorous process of blind peer review and edited by an interdisciplinary scientific editorial committee. Topics range from symmetry in ancient Persian architecture to the elaborate geometric patterns and complex three-dimensional structures of standing monuments of historical periods, from the expression of mathematical ideas to architectonic structures, and from decorative ornament to the representation of modern group theory and quasi-crystalline patterns. The articles discuss unique monuments Persia, including domed structures and two-dimensional patterns, which have received significant scholarly attention in recent years. This book is a unique contribution to studies of Persian architecture in relation to mathematics.

  5. Architecture of Environmental Engineering

    DEFF Research Database (Denmark)

    Wenzel, Henrik; Alting, Leo

    2006-01-01

    An architecture of Environmental Engineering has been developed comprising the various disciplines and tools involved. It identifies industry as the major actor and target group, and it builds on the concept of Eco-efficiency. To improve Eco-efficiency, there is a limited number of intervention......-efficiency is the aim of Environmental Engineering, the discipline of synthesis – design and creation of solutions – will form a core pillar of the architecture. Other disciplines of Environmental Engineering exist forming the necessary background and frame for the synthesis. Environmental Engineering, thus, in...... essence comprise the disciplines of: management, system description & inventory, analysis & assessment, prioritisation, synthesis, and communication, each existing at all levels of intervention. The developed architecture of Environmental Engineering, thus, consists of thirty individual disciplines...

  6. Architecture of Environmental Engineering

    DEFF Research Database (Denmark)

    Wenzel, Henrik; Alting, Leo

    2004-01-01

    An architecture of Environmental Engineering has been developed comprising the various disciplines and tools involved. It identifies industry as the major actor and target group, and it builds on the concept of Eco-efficiency. To improve Eco-efficiency, there is a limited number of intervention...... of Eco-efficiency is the aim of Environmental Engineering, the discipline of synthesis – design and creation of solutions – will form a core pillar of the architecture. Other disciplines of Environmental Engineering exist forming the necessary background and frame for the synthesis. Environmental...... Engineering, thus, in essence comprise the disciplines of: management, system description & inventory, analysis & assessment, prioritisation, synthesis, and communication, each existing at all levels of intervention. The developed architecture of Environmental Engineering, thus, consists of thirty individual...

  7. Knowledge Work and Knowledge Creation

    DEFF Research Database (Denmark)

    Dau, Susanne

    2016-01-01

    instructions in respectively teacher and radiographyundergraduate educations influences the student’s creativity and knowledge creation in the use of virtualmedia?The paper is based on a longitudinal case study of two classes of teacher and radiography students’wayfinding within blended learning environments......The purpose of this paper is to address how instruction influences the creative knowledge work.Based on different perspectives on instructions and the actions followed, this paper reveal how educators,having different competencies of ICT-instructions,influence students’ creative knowledge work......, andstudents’ knowledge creation.The paper's contribution to the existing knowledge is founded in a metaphorical phenomenologicalecologicalapproach to learning as wayfinding inspired by Ahmeds´ (2006) phenomenological theory oforientation and Ingold´s (2000) ecological concept of wayfinding. According...

  8. Clustering-based support for software architecture restructuring

    CERN Document Server

    Streekmann, Niels

    2011-01-01

    The maintenance of long-living software systems is an essential topic in today's software engineering practice and research. Software Architecture Restructuring is an important task to adjust these systems to current requirements and to keep them maintainable. Niels Streekmann introduces an approach to Software Architecture Restructuring that semi-automates this task by introducing graph clustering. The approach provides an iterative process that systematically incorporates human architectural knowledge for the improvement of the restructuring result. Thus, it supports the task of planning the

  9. Climatic architecture: Situation, principles, establishment of technical policies

    International Nuclear Information System (INIS)

    Climatic architecture, despite the efforts of its protagonists, remains nearly marginal. Nevertheless, environmental awareness is gaining ground, whether through concern for the depletion of natural resources, for global warming or for CO2 emissions. It is only by establishing technical policies, making an effort in terms of training and research and distributing knowledge to all those in the business that the principles of climatic architecture will actually be applied in the field. Resources are available to make climatic architecture a fundamental concern in the design of environmentally friendly buildings. (author). 6 refs, 3 tabs

  10. Towards an Architectural Anthropology

    DEFF Research Database (Denmark)

    Stender, Marie

    2016-01-01

    Architecture and anthropology have always had overlapping interests regarding issues such as spatial organisation, forms of human dwellings and the interplay between social life and physical surroundings. Recent developments in both disciplines make it even more relevant to explore and evolve their...... overlaps and collaboration. However, there are also challenging differences to take into account regarding disciplinary traditions of e.g. communication, temporality and normativity. This article explores the potentials and challenges of architectural anthropology as a distinct sub-discipline, and outlines...

  11. Synergetics and architecture

    Science.gov (United States)

    Maslov, V. P.; Maslova, T. V.

    2008-03-01

    A series of phenomena pertaining to economics, quantum physics, language, literary criticism, and especially architecture is studied from the standpoint of synergetics (the study of self-organizing complex systems). It turns out that a whole series of concrete formulas describing these phenomena is identical in these different situations. This is the case of formulas relating to the Bose-Einstein distribution of particles and the distribution of words from a frequency dictionary. This also allows to apply a "quantized" from of the Zipf law to the problem of the authorship of Quiet Flows the Don and to the "blending in" of new architectural structures in an existing environment.

  12. Reframing information architecture

    CERN Document Server

    Resmini, Andrea

    2014-01-01

    Information architecture has changed dramatically since the mid-1990s and earlier conceptions of the world and the internet being different and separate have given way to a much more complex scenario in the present day. In the post-digital world that we now inhabit the digital and the physical blend easily and our activities and usage of information takes place through multiple contexts and via multiple devices and unstable, emergent choreographies. Information architecture now is steadily growing into a channel- or medium-specific multi-disciplinary framework, with contributions coming from a

  13. Interactive Architecture #1

    OpenAIRE

    Oosterhuis, K.; X. Xia

    2007-01-01

    The iA bookzine series will consist of twelve issues, bi-annually published over a period of six years under the supervision of Prof. ir. Kas Oosterhuis, director of the Hperbody at the Delft University of Technology. Interactive Architecture - from here on abbreviated as iA - is NOT simply architecture that is responsive or adaptive to changing circumstances. On the contrary, iA is based on the concept of bi-directional communication, which requires two active parties. Naturally, communicati...

  14. Radio-Communications Architectures

    OpenAIRE

    Diet, Antoine; Villegas, Martine; Baudoin, Genevieve; Robert, Fabien

    2010-01-01

    The goal of this chapter is to demonstrate the absolute need of matching the architecture design and the signal carrying the information. In section 1 and 2, considerations about current users' needs helped to identify three types of carrier signals in the context of radio-communications: NB-CW, WB-CW and IR. A separation between CW and IR signals is unavoidable because it drives us to a different technological design. Basic blocks of transmitter architecture are optimized in function with th...

  15. Conventionalized knowledge

    DEFF Research Database (Denmark)

    Buus, Niels

    2006-01-01

    Mental health nurses routinely hand over clinical knowledge at intershift reports. In the present study, field descriptions from prolonged fieldwork and transcripts of audio recordings of handovers were analysed discursively drawing on ethnomethodology and conversation analysis. The analysis iden...

  16. Knowledge Gaps

    DEFF Research Database (Denmark)

    Lyles, Marjorie; Pedersen, Torben; Petersen, Bent

    2003-01-01

    , assimilating, and utilizing knowledge - are crucial determinants ofknowledge gap elimination. In contrast, the two factors deemed essential in traditionalinternationalization process theory - elapsed time of operations and experientiallearning - are found to have no or limited effect.Key words...

  17. Knowledge Test

    DEFF Research Database (Denmark)

    Sørensen, Ole Henning

    1998-01-01

    The knowledge test is about competing temporal and spatial expressions of the politics of technological development and national prosperity in contemporary society. The discussion is based on literature of national systems of innovation and industrial networks of various sorts. Similarities...

  18. Knowledge brokering

    DEFF Research Database (Denmark)

    Bergenholtz, Carsten

    2011-01-01

    implications – An organization that can span both technological boundaries and weak ties is in a unique knowledge brokering position. The findings indicate how the barriers of an open transfer of complex knowledge across weak ties can be partially overcome by letting an R&D department be the networking......Purpose – The purpose of this paper is to examine how the spanning of inter-organizational weak ties and technological boundaries influences knowledge brokering. Design/methodology/approach – The paper is based on original fieldwork and employs a case study research design, investigating a Danish...... HTSF’s inter-organizational activities. Findings – The findings show how an inter-organizational search that crosses technological boundaries and is based on a network structure of weak ties can imply a reduced risk of unwanted knowledge spill-over. Research limitations/implications – By not engaging...

  19. Information architecture. Volume 3: Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The purpose of this document, as presented in Volume 1, The Foundations, is to assist the Department of Energy (DOE) in developing and promulgating information architecture guidance. This guidance is aimed at increasing the development of information architecture as a Departmentwide management best practice. This document describes departmental information architecture principles and minimum design characteristics for systems and infrastructures within the DOE Information Architecture Conceptual Model, and establishes a Departmentwide standards-based architecture program. The publication of this document fulfills the commitment to address guiding principles, promote standard architectural practices, and provide technical guidance. This document guides the transition from the baseline or defacto Departmental architecture through approved information management program plans and budgets to the future vision architecture. This document also represents another major step toward establishing a well-organized, logical foundation for the DOE information architecture.

  20. Hybrid Neural Network Architecture for On-Line Learning

    CERN Document Server

    Chen, Yuhua; Wang, Lei

    2008-01-01

    Approaches to machine intelligence based on brain models have stressed the use of neural networks for generalization. Here we propose the use of a hybrid neural network architecture that uses two kind of neural networks simultaneously: (i) a surface learning agent that quickly adapt to new modes of operation; and, (ii) a deep learning agent that is very accurate within a specific regime of operation. The two networks of the hybrid architecture perform complementary functions that improve the overall performance. The performance of the hybrid architecture has been compared with that of back-propagation perceptrons and the CC and FC networks for chaotic time-series prediction, the CATS benchmark test, and smooth function approximation. It has been shown that the hybrid architecture provides a superior performance based on the RMS error criterion.

  1. Brain Basics

    Medline Plus

    Full Text Available ... the anatomy, physiology, and chemistry of the nervous system. When the brain cannot effectively coordinate the billions ... basic working unit of the brain and nervous system. These cells are highly specialized for the function ...

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    Medline Plus

    Full Text Available ... the brain cannot effectively coordinate the billions of cells in the body, the results can affect many ... unit of the brain and nervous system. These cells are highly specialized for the function of conducting ...

  3. Brain Basics

    Medline Plus

    Full Text Available ... Neurons & Neural Circuits Neurons are the basic working unit of the brain and nervous system. These cells ... A nerve cell that is the basic, working unit of the brain and nervous system, which processes ...

  4. Brain Basics

    Medline Plus

    Full Text Available ... Trials — Participants Statistics Help for Mental Illnesses Outreach Research Priorities Funding Labs at NIMH News About Us Home > Health & Education > Educational Resources Brain Basics Introduction The Growing Brain The ...

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    Full Text Available ... brain may play a role in disorders like schizophrenia or attention deficit hyperactivity disorder (ADHD) . Glutamate —the ... mental disorders, including autism , obsessive compulsive disorder (OCD) , schizophrenia , and depression . Brain Regions Just as many neurons ...

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    Full Text Available ... medical professionals who can diagnose mental disorders are psychologists or clinical social workers. The psychiatrist asked Sarah ... important research tool in understanding how the brain functions. Another type of brain scan called magnetoencephalography, or ...

  7. Brain Basics

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  11. Brain Basics

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    Full Text Available ... problems using dopamine in the thinking and feeling regions of the brain may play a role in ... obsessive compulsive disorder (OCD) , schizophrenia , and depression . Brain Regions Just as many neurons working together form a ...

  12. Brain Basics

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    Full Text Available ... medications could reduce the amount of trial and error and frustration that many people with depression experience ... early brain development, and may also assist in learning and memory. hippocampus —A portion of the brain ...

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    Full Text Available ... Life Brain Basics in Real Life—How Depression affects the Brain Meet Sarah Sarah is a middle- ... However, recent research points to a possible new class of antidepressants that can relieve symptoms of the ...

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    Full Text Available ... have been linked to many mental disorders, including autism , obsessive compulsive disorder (OCD) , schizophrenia , and depression . Brain ... studies show that brain growth in children with autism appears to peak early. And as they grow ...

  17. Brain Basics

    Medline Plus

    Full Text Available ... body, the results can affect many aspects of life. Scientists are continually learning more about how the brain grows and works in healthy people, and how normal brain development ...

  18. Brain Diseases

    Science.gov (United States)

    The brain is the control center of the body. It controls thoughts, memory, speech, and movement. It regulates the function of many organs. When the brain is healthy, it works quickly and automatically. However, ...

  19. Brain Basics

    Medline Plus

    Full Text Available ... working unit of the brain and nervous system. These cells are highly specialized for the function of ... nerve cells (via axons) to form brain circuits. These circuits control specific body functions such as sleep ...

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