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Sample records for bp010009 cambridge biotech

  1. Voices of biotech

    DEFF Research Database (Denmark)

    Amit, Ido; Baker, David; Barker, Roger; Berger, Bonnie; Bertozzi, Carolyn; Bhatia, Sangeeta; Biffi, Alessandra; Demichelis, Francesca; Doudna, Jennifer; Dowdy, Steven F.; Sommer, Morten Otto Alexander; Zhang, Tian

    2016-01-01

    What will be the most important areas of research in biotech over the coming years? Which technologies will be most important to advance knowledge and applications in these areas? Nature Biotechnology reached out to a set of investigators working in research areas representative of the journal's ...

  2. Philosophy at Cambridge

    OpenAIRE

    Lecky-Thompson, Jenni

    2012-01-01

    Newsletter of the Philosophy Faculty. Articles by: Simon Blackburn, 'From the Chair' ; Nick Treanor, 'Inaugural lecture: What is distinctive about human thought?' ; Clare Chambers, 'Political Philosophy at Cambridge' ; Alexis Papazoglou,'Aspects of philosophy at Cambridge' ; Peter Smith, 'Principia at 100' ; Nigel Crisp, 'Turning the World Upside Down' ; Cain Todd, 'Fiction, Emotion, Imagination'; Fraser MacBride, 'Philosophy, St John's, Cambridge, 1986.'

  3. Quo vadis, biotech? (Part 2).

    Science.gov (United States)

    Drews, J

    2001-01-01

    Those following the financial markets and the valuation of biotechnology companies recently might find themselves perplexed. Towards the end of 1999, during which the availability of capital for biotech initial public offerings and for private investment rounds seemingly withered, the markets suddenly turned around and gave the biotechnology industry its biggest bonanza ever. PMID:11165169

  4. NMSBA: Sandia Biotech 2016 Report

    Energy Technology Data Exchange (ETDEWEB)

    Ruffing, Anne [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-06-01

    The objective of this project is to modify the FluorAbody plasmid previously developed by Sandia Biotech to include a binding site for biotin by introducing the biotin carboxyl carrier protein (BCCP)and a gold binding protein (GBP) into a loop of the red fluorescent protein (mRFP).

  5. Buying big into biotech: scale, financing, and the industrial dynamics of UK biotech, 1980–2009

    OpenAIRE

    Hopkins, M.M.; Crane, P.A.; Nightingale, P.; Baden-Fuller, C.

    2013-01-01

    This article explores how the UK's biotech firms have evolved in response to their financial environment. As investors' expectations about the potential of biotech have changed, funding options have opened up and closed down, leading firms to develop new business models and routes of technology development. After a favorable period, new constraints on stock market funding have forced UK biotech firms to compress their life cycles, constraining their ability to generate the late-stage drug can...

  6. On Ricardo and Cambridge

    OpenAIRE

    Geoff C. Harcourt; Peter Kriesler

    2014-01-01

    David Ricardo’s key place in the history of economic thought is well established. However, both the understanding of his Principles of Political Economy and Taxation and its role in the development of economic analysis is much more controversial. Cambridge economists have contributed significantly to both of these issues. They have played an important part in two extremely divergent interpretations of Ricardo’s place in the development of economic thought. Understanding how Ricardo has been v...

  7. Cambridge IGCSE computer science

    CERN Document Server

    Watson, Dave; Konrad, Nina

    2015-01-01

    Endorsed by Cambridge International Examinations. Develop your students computational thinking and programming skills with complete coverage of the latest syllabus (0478) from experienced examiners and teachers. - Includes a Student CD-ROM with interactive tests, based on the short answer questions from both papers - Follows the order of the syllabus exactly, ensuring complete coverage - Introduces students to self-learning exercises, helping them learn how to use their knowledge in new scenarios This syllabus is for first examination from 2015.

  8. Structure, Employment and Performance in Biotech Firms

    DEFF Research Database (Denmark)

    Valentin, Finn; Dahlgren, Johan Henrich; Lund Jensen, Rasmus

    2006-01-01

    biotech firms in a relevant context we compare a Danish segment of biotech firms with a matching Swedish segment.From an overall assessment modern biotechnology, despite the three decades elapsed since the first genetic manipulation, is still in a stage of experimentation, learning how to turn its new...... segment of Drug Discovery Firms (DDFs), which almost exclusively are based on capabilities in biotech research. This delimitation gives the advantage of studying a homogenous segment of firms. At the same time, this segment of biotech research firms is an informative indicator of the ability of the Danish...... economy to perform in the transition towards knowledge and sciencebased competitiveness. That is so because DDFs to an unusual extent depend on the ability of their framework to perform as an innovation system, by which we refer to advantages growing out of interactions and complementarities between e...

  9. Business Ethics 101 for the biotech industry.

    Science.gov (United States)

    MacDonald, Chris

    2004-01-01

    Biotechnology companies face ethical challenges of two distinct types: bioethical challenges faced on account of the nature of work in the life sciences, and corporate ethical challenges on account of their nature as commercial entities. The latter set of challenges has received almost no attention at all in the academic literature or media. This paper begins to remedy that lacuna, examining ethical issues that arise specifically on account of the status of biotech companies as commercial entities. The focus here is on three representative issues: product safety, corporate social responsibility, and corporate governance. It is argued that each of these issues poses particular ethical challenges for companies in the biotech sector. In the area of product safety, it is noted that biotech companies face particular challenges in determining what counts as a "safe" product, given the contentious nature of what might count as a "harm" in the biotech field. In the area of corporate social responsibility, the adoption of a "stakeholder approach" and an attempt to manage the social consequences of products pose special challenges for biotech companies. This is due to the enormous range of groups and individuals claiming to have a stake in the doings of such companies, and the trenchant controversies over just what the social consequences of various biotechnologies might be. In the area of corporate governance, biotech companies need to seek out and follow best practices regarding the ways in which information, authority, and influence flow between a company's shareholders, managers, and Board of Directors, if they are to avoid duplicating the ethical and financial scandal that brought down ImClone. An important meta-issue, here--one that renders each of these corporate ethical challenges more vexing--is the difficulty of finding the appropriate benchmarks for ethical corporate behavior in a field as controversial, and as rapidly evolving, as biotechnology. Three

  10. Financial Risk of the Biotech Industry versus the Pharmaceutical Industry

    OpenAIRE

    Joseph Golec

    2009-01-01

    The biotech industry now accounts for a substantial and growing proportion of total R&D spending on new medicines. However, compared with the pharmaceutical industry, the biotech industry is financially fragile. This article illustrates the financial fragility of the biotech and pharmaceutical industries in the US and the implications of this fragility for the effects that government regulation could have on biotech firms. Graphical analysis and statistical tests were used to show how the bio...

  11. Neuro-oncology biotech industry progress report.

    Science.gov (United States)

    Chakraborty, Shamik; Bodhinayake, Imithri; Chiluwal, Amrit; Langer, David J; Ruggieri, Rosamaria; Symons, Marc; Boockvar, John A

    2016-05-01

    The Brain Tumor Biotech Center at the Feinstein Institute for Medical Research, in collaboration with Voices Against Brain Cancer hosted The Brain Tumor Biotech Summit at in New York City in June 2015. The focus was once again on fostering collaboration between neuro-oncologist, neurosurgeons, scientists, leaders from biotechnology and pharmaceutical industries, and members of the financial community. The summit highlighted the recent advances in the treatment of brain tumor, and specifically focused on targeting of stem cells and EGFR, use of prophage and immunostimulatory vaccines, retroviral vectors for drug delivery, biologic prodrug, Cesium brachytherapy, and use of electric field to disrupt tumor cell proliferation. This article summarizes the current progress in brain tumor research as presented at 2015 The Brain Tumor Biotech Summit. PMID:26897014

  12. International Commercial Contracts, by Giuditta Cordero Moss. (Cambridge: Cambridge University Press, 2014)

    DEFF Research Database (Denmark)

    Lando, Ole

    2015-01-01

    Review of: Giuditta Cordero Moss, International Commercial Contracts. Cambridge: Cambridge University Press, 2014. XV + 329 pages. ISBN: 9781107684713......Review of: Giuditta Cordero Moss, International Commercial Contracts. Cambridge: Cambridge University Press, 2014. XV + 329 pages. ISBN: 9781107684713...

  13. The Cambridge Structural Database.

    Science.gov (United States)

    Groom, Colin R; Bruno, Ian J; Lightfoot, Matthew P; Ward, Suzanna C

    2016-04-01

    The Cambridge Structural Database (CSD) contains a complete record of all published organic and metal-organic small-molecule crystal structures. The database has been in operation for over 50 years and continues to be the primary means of sharing structural chemistry data and knowledge across disciplines. As well as structures that are made public to support scientific articles, it includes many structures published directly as CSD Communications. All structures are processed both computationally and by expert structural chemistry editors prior to entering the database. A key component of this processing is the reliable association of the chemical identity of the structure studied with the experimental data. This important step helps ensure that data is widely discoverable and readily reusable. Content is further enriched through selective inclusion of additional experimental data. Entries are available to anyone through free CSD community web services. Linking services developed and maintained by the CCDC, combined with the use of standard identifiers, facilitate discovery from other resources. Data can also be accessed through CCDC and third party software applications and through an application programming interface. PMID:27048719

  14. Partnership between small biotech and big pharma.

    Science.gov (United States)

    Wiederrecht, Gregory J; Hill, Raymond G; Beer, Margaret S

    2006-08-01

    The process involved in the identification and development of novel breakthrough medicines at big pharma has recently undergone significant changes, in part because of the extraordinary complexity that is associated with tackling diseases of high unmet need, and also because of the increasingly demanding requirements that have been placed on the pharmaceutical industry by investors and regulatory authorities. In addition, big pharma no longer have a monopoly on the tools and enabling technologies that are required to identify and discover new drugs, as many biotech companies now also have these capabilities. As a result, researchers at biotech companies are able to identify credible drug leads, as well as compounds that have the potential to become marketed medicinal products. This diversification of companies that are involved in drug discovery and development has in turn led to increased partnering interactions between the biotech sector and big pharma. This article examines how Merck and Co Inc, which has historically relied on a combination of internal scientific research and licensed products, has poised itself to become further engaged in partnering with biotech companies, as well as academic institutions, to increase the probability of success associated with identifying novel medicines to treat unmet medical needs--particularly in areas such as central nervous system disorders, obesity/metabolic diseases, atheroma and cancer, and also to cultivate its cardiovascular, respiratory, arthritis, bone, ophthalmology and infectious disease franchises. PMID:16871465

  15. The Cambridge Experimentation Review Board

    Science.gov (United States)

    Bulletin of the Atomic Scientists, 1977

    1977-01-01

    Reproduced is the report made by a citizens' group in Cambridge, Massachusetts and presented to the city council that outlines safety regulations for the conduct of recombinant DNA research at Harvard University and the Massachusetts Institute of Technology. (CS)

  16. Clark and Prehistory at Cambridge

    OpenAIRE

    Pamela Jane Smith

    1996-01-01

    If honours and titles give measure of a man, then Professor Sir Grahame Clark was indeed important. Faculty Assistant Lecturer in the Faculty of Archaeology and Anthropology at Cambridge University from 1935-46, University Lecturer 1946-52, Disney Professor of Archaeology 1952-74, Head of the Department of Archaeol­ogy and Anthropology 1956-61 and 1968-71, Fellow of Peterhouse, Cambridge 1950-73, Master of Peterhouse 1...

  17. Communicating financials in the biotech industry

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte

    2008-01-01

    In Denmark, biotechnology and its physical product, the genetically modified organism, continues to be controversial, leading to widespread public scepticism. This paper explores the effect of such scepticism on part of the financial communication of one of Denmark's largest biotech companies......, Novozymes. Research indicates that besides accommodating a legal demand for the disclosure of company financial details, the annual report, in particular the letter to the shareholders or the CEO's letter, serves the purpose of marketing the company to its constituents (Bowman 1984; Bülow-Møller 2003......; Hyland 1998). This point is arguably of more importance to a biotech company which in its communication to the public may have to consider promoting an overly favourable and trustworthy image not only of its financial results, but also of the industry in which it is engaged, to ensure continuous...

  18. Clark and Prehistory at Cambridge

    Directory of Open Access Journals (Sweden)

    Pamela Jane Smith

    1996-05-01

    Full Text Available If honours and titles give measure of a man, then Professor Sir Grahame Clark was indeed important. Faculty Assistant Lecturer in the Faculty of Archaeology and Anthropology at Cambridge University from 1935-46, University Lecturer 1946-52, Disney Professor of Archaeology 1952-74, Head of the Department of Archaeol­ogy and Anthropology 1956-61 and 1968-71, Fellow of Peterhouse, Cambridge 1950-73, Master of Peterhouse 1973-80, he was a visiting lecturer at diverse universities; appointed CBE in 1971, he received many awards includ­ing the prestigious Erasmus Prize for 1990, presented by Prince Bernhard of the Netherlands, for his "long and inspiring devotion to prehistory" (Scarre 1991:10; and in June 1992, he was knighted. Yet well before fame and position were rewards, Clark made major contributions to the establishment of prehis­tory as an academic subject at Cambridge University. Cambridge was the first and, for many years, only British university granting an undergraduate degree which offered prehistory as a specialization. "The development of postgraduate research in prehistoric archaeology at Cambridge had to wait on the provision of undergraduate teaching;' Clark (1989b: 6 recently observed. The "faculty was the only one in Britain producing a flow of graduates in prehistoric archaeology" (Clark 1989a: 53.

  19. Cambridge IGCSE English first language

    CERN Document Server

    Reynolds, John

    2013-01-01

    Revised edition for the 2015 syllabus to help your students prepare for their examination and enhance their enjoyment of English. This title has been written for the revised Cambridge IGCSE First Language English (0500 and 0522) syllabuses, for first teaching from 2013. ? Develops the skills necessary to become a better reader and writer. ? Offers detailed advice and preparation for the examination. ? Teaches skills for successful writing of essays and coursework assignment. We are working with Cambridge International Examinations to gain endorsement for this title.

  20. Cambridge checkpoint English workbook 1

    CERN Document Server

    Reynolds, John

    2013-01-01

    This Workbook supports our bestselling Checkpoint English series, with exercises specifically matched to the Cambridge Progression tests and the Checkpoint English tests. - Offers plenty of additional questions for use in class or as homework. - Includes clearly identified questions on grammar and punctuation, comprehension, use of language and essay planning. - Follows the structure of the relevant textbook to ensure a thorough understanding of all aspects of the course. - Provides a space for Students to write their answers. This Workbook is matched to the Cambridge Secondary 1 Curriculum Fr

  1. Data sharing at the University of Cambridge - open presentation for Cambridge academics, students and research staff

    OpenAIRE

    Teperek, Marta

    2016-01-01

    Presentation about research data sharing at the University of Cambridge given by Dr Marta Teperek on 20 January at central Cambridge, University of Cambridge. Presenation was open to all academics, research students and staff members.

  2. 77 FR 35353 - Biotech Life Sciences Trade Mission to Australia

    Science.gov (United States)

    2012-06-13

    ... International Trade Administration Biotech Life Sciences Trade Mission to Australia AGENCY: International Trade... Biotech Life Sciences trade mission to Australia, October 29-November 2, 2012. The mission to Australia is... of the trade mission to Australia are to (1) increase U.S. exports to Australia, (2) introduce...

  3. 76 FR 17621 - Biotech Life Science Trade Mission to China

    Science.gov (United States)

    2011-03-30

    ... International Trade Administration Biotech Life Science Trade Mission to China AGENCY: International Trade.... biotechnology and life science firms and trade organizations. The mission will introduce mission participants to.... Commercial Setting U.S. biotech and life science firms often consider China the most important future...

  4. The Cambridge Infectious Diseases Consortium

    OpenAIRE

    Wood, James

    2010-01-01

    The Cambridge Infectious Diseases Consortium (CIDC) was established to provide a multi-institutional, world class quality environment for infectious disease research addressing important questions and for the recruitment and training of high quality veterinarians into careers in infectious disease research. The programme has been a demonstrable success in achieving these overall aims. The institutions that have played a key role in the consortium include the Department of Veterinary Medic...

  5. Financial risk of the biotech industry versus the pharmaceutical industry.

    Science.gov (United States)

    Golec, Joseph; Vernon, John A

    2009-01-01

    The biotech industry now accounts for a substantial and growing proportion of total R&D spending on new medicines. However, compared with the pharmaceutical industry, the biotech industry is financially fragile. This article illustrates the financial fragility of the biotech and pharmaceutical industries in the US and the implications of this fragility for the effects that government regulation could have on biotech firms. Graphical analysis and statistical tests were used to show how the biotech industry differs from the pharmaceutical industry. The two industries' characteristics were measured and compared, along with various measures of firms' financial risk and sensitivity to government regulation. Data from firms' financial statements provided accounting-based measures and firms' stock returns applied to a multifactor asset pricing model provided financial market measures. The biotech industry was by far the most research-intensive industry in the US, averaging 38% R&D intensity (ratio of R&D spending to total firm assets) over the past 25 years, compared with an average of 25% for the pharmaceutical industry and 3% for all other industries. Biotech firms exhibited lower and more volatile profits and higher market-related and size-related risk, and they suffered more negative stock returns in response to threatened government price regulation. Biotech firms' financial risks increase their costs of capital and make them more sensitive to government regulations that affect their financial prospects. As biotech products grow to represent a larger share of new medicines, general stock market conditions and government regulations could have a greater impact on the level of innovation of new medicines. PMID:19799470

  6. Health care biotech industry (Review Paper

    Directory of Open Access Journals (Sweden)

    G Padmanaban

    2001-10-01

    Full Text Available Modern biotechnology became possible because of the ability to clone genes and produce gene products barriers of species and sex. Potential entrepreneurs are getting interested in venturing into health care biotech industry, stimulated by the success story in information technology. Products of protein therapeutics, such as insulin, growth hormones, interferons, blood proteins, streptokinase and vaccines have received special attention. Pharmaceutical companies got into the field of diagnostics, a major thrust area being products of antigen/antibody and nucleic acid-based diagnostic kits. The ability to clone and sequence genes from a variety of organisms has culminated in the subject of genomics. High throughput screening of thousands of organic molecules against a battery of drug targets using robotic machinery is the current approach to come up with lead molecules. New drug delivery systems for slow, sustained and direct delivery to target tissues are under way. There is hope that hereditary and metabolic disorders may have a cure through replacements of defective genes by normal cloned genes and by blocking the expression of unwanted genes, respectively. This mega approach would call for the availability of DNA chips, a product of collaboration between molecular biologists and electronic engineers. The tendency now-a-days is for a marriage between biotech and pharmaceutical industries. Animal cloning, spearheaded by the birth of Dolly, has revolutionised cell biology and is of promise to generate animal bio-vectors to produce desired protein pharmaceuticals in milk. Stem cell research has assumed a lot of importance. In our country, reasonable competence has been built-up in the field of biotechnology. Around two dozen institutes carry out front-line research in medical biotechnology. Successful commercialisation of a few diagnostic kits and recombinant vaccines has provided an impetus and enthusiasm to exploit biotechnology in a big way

  7. Honorary Degree Congregation in Cambridge

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    One day in mid-June 2006 when I was on a visit to the Countryside Restoration Trust at Barton near Cambridge, Mr. Christopher Stevenson, the director of Program of Events for Newcomers & Academic Visitors, gave me a letter enclosing a notice and a ticket I booked nearly two months earlier. He told me that I was very lucky because a strictly limited number of tickets had been allocated to academic visitors. It was a ticket to admit me to the Honorary Degree Congregation and to the reception afterwards on Tuesday 27 June.

  8. Scientific knowledge dynamics and relatedness in biotech cities

    OpenAIRE

    Boschma, Ron; Heimeriks, Gaston; Balland, Pierre-Alexandre

    2014-01-01

    This paper investigates the impact of scientific relatedness on knowledge dynamics in biotech at the city level during the period 1989-2008. We assess the extent to which the emergence of new research topics and the disappearance of existing topics in cities are dependent on their degree of scientific relatedness with existing topics in those cities. We make use of the rise and fall of title words in scientific publications in biotech to identify major cognitive developments within the field....

  9. Scientific Knowledge Dynamics and Relatedness in Bio-Tech Cities

    OpenAIRE

    Ron Boschma; Gaston Heimeriks; Pierre-Alexandre Balland

    2013-01-01

    This paper investigates the impact of scientific relatedness on knowledge dynamics in biotech at the city level during the period 1989-2008. We assess the extent to which the emergence of new research topics and the disappearance of existing topics in cities are dependent on their degree of scientific relatedness with existing topics in those cities. We make use of the rise and fall of title words in scientific publications in biotech to identify major cognitive developments within the field....

  10. Cambridge physics in the thirties

    International Nuclear Information System (INIS)

    This book is a collection of reminiscences of many of the distinguished physicists who worked in Cambridge, mainly at the Cavendish Laboratory, during the early 1930s. The background to and sequence of theories and experiments which led to many important discoveries are given. Of particular interest are Chadwick's discovery of the neutron, the splitting of the atom by Cockcroft and Walton, the demonstration by Blackett and Occhialini of the existence of the positron, the fusion of deuterium nuclei by Rutherford and Oliphant and Chadwick and Goldhaber's demonstration of the nuclear photoelectric effect and derivation of the first accurate figure for the mass of the neutron. Thirteen chapters relevant to these are indexed separately. The others are more concerned with personalities and personal reminiscences. (UK)

  11. Trial access to Cambridge University Press ebooks

    CERN Multimedia

    CERN Library

    2011-01-01

    From 1 August till 31 October, CERN users are invited to enjoy a trial access to all Cambridge University Press electronic books: http://ebooks.cambridge.org/. Please don't hesitate to send feedback to library.desk@cern.ch.

  12. [Mexico recovers leadership on regulation of biosimilar biotech drugs].

    Science.gov (United States)

    López Silva, Christian

    2012-01-01

    Amid the epidemiological transition that Mexico is currently experiencing, an adequate access to biotech medicines is becoming very important. However, these medicines also involve new challenges for the sanitary authorities, given their higher complexity in structure and function than conventional chemical drugs. Consequently, it has been necessary to update the Mexican legal framework, which has placed Mexico at the forefront in this sector. This article describes briefly what biotech drugs are, why it has been necessary to regulate them differently, the evolution of the regulatory framework in Mexico, and the general features of the new system. PMID:22367313

  13. China's Biotech Policies and Their Impacts on U.S. Agricultural Exports to China

    OpenAIRE

    Song, Baohui; Marchant, Mary A.

    2006-01-01

    China is a key player in global agricultural markets, and the number one importer of U.S. soybeans and cotton, whereby soybeans and cotton are two of the main biotech commodities commercialized in the United States. As of 2005, 87% of soybeans and 79% of cotton planted in the U.S. were biotech. Thus, changes in China's biotech policies may have a significant impact on U.S. biotech commodity exports to China. An understanding of the evolution of China's biotech regulations and factors that may...

  14. Cambridge checkpoint English revision guide for the Cambridge secondary 1 test

    CERN Document Server

    Reynolds, John

    2013-01-01

    With Checkpoint English Revision Guide for the Cambridge Secondary 1 test you can aim for the best grade with the help of relevant and accessible notes, examiner advice plus questions and answers on each key topic. - Clear explanations of every topic covered in the Cambridge Secondary 1 Checkpoint English syllabus. - Builds revision skills you need for success in the test. - Exam tips wirtten by test setters and examiners giving you their expert advice. This text has not been through the Cambridge endorsement process.

  15. Cambridge checkpoint maths revision guide for the Cambridge secondary 1 test

    CERN Document Server

    Smith, Alan

    2013-01-01

    With Checkpoint Maths Revision Guide for the Cambridge Secondary 1 test you can aim for the best grade with the help of relevant and accessible notes, examiner advice plus questions and answers on each key topic. - Clear explanations of every topic covered in the Cambridge Secondary 1 Checkpoint Maths syllabus. - Builds revision skills you need for success in the test. - Exam tips wirtten by test setters and examiners giving you their expert advice. This text has not been through the Cambridge endorsement process.

  16. Combining Instructionist and Constructionist Learning in a Virtual Biotech Lab.

    Science.gov (United States)

    Dawabi, Peter; Wessner, Martin

    The background of this paper is an internal research project at the German National Research Center for Information Technology, Integrated Publication and Information Systems Institute, (GMD-IPSI) dealing with software engineering, computer-supported cooperative learning (CSCL) and practical biotech knowledge. The project goal is to develop a…

  17. MARKETING OF BIOTECH FUNCTIONAL FOODS IN THE US

    OpenAIRE

    Chema, Kambua; Marks, Leonie A.; Parcell, Joseph L.; Bredahl, Maury E.

    2004-01-01

    To date, most research in Europe and the United States has focused on eliciting consumer WTP for biotech foods without directly addressing strategies for marketing them. We use means-end theory to link consumers' knowledge about functional attributes, to their knowledge about consequences and core values, in order to gain insights into valued attributes for developing potential marketing strategies.

  18. Cambridge IGCSE mathematics core and extended

    CERN Document Server

    Pimentel, Ric

    2013-01-01

    The most cost effective and straightforward way to teach the revised syllabus, with all the core and extended content covered by a single book and accompanying free digital resources.  . This title has been written for the revised Cambridge IGCSE Mathematics (0580) syllabus, for first teaching from 2013.  . ·         Gives students the practice they require to deepen their understanding through plenty of questions. ·         Consolidates learning with unique digital resources on the CD, included free with every Student's Book.  . We are working with Cambridge International Examinations to gain

  19. The Cambridge Jet Algorithm features and applications

    CERN Document Server

    Bentvelsen, Stanislaus Cornelius Maria

    1998-01-01

    Jet clustering algorithms are widely used to analyse hadronic events in high energy collisions. Recently a new clustering method, known as `Cambridge', has been introduced. In this article we present an algorithm to determine the transition values of ycut for this clustering scheme, which allows to resolve any event to a definite number of jets in the final state. We discuss some particularities of the Cambridge clustering method and compare its performance to the Durham clustering scheme for Monte Carlo generated e+e- annihilation events.

  20. OCR Cambridge nationals in ICT student book

    CERN Document Server

    Stuart, Sonia; Cushing, Steve

    2012-01-01

    Written by experts and in partnership with OCR, the brand-new OCR Cambridge Nationals in ICT Student's Book provides invaluable guidance for your teaching of the OCR Cambridge Nationals in ICT Level 1/2 . This textbook covers the mandatory Units 1 and 2 in detail, offering your students the knowledge and practice they require. Unit 1 - Understanding Computer Systems.; Coverage of use of applications and systems.; Case studies of how they are used for different purposes.; Exam style questions and guidance. Unit 2 - Using ICT to Create Business Solutions.; Coverage of the principles of use of re

  1. Development of polymeric drug delivery systems for biotech products

    OpenAIRE

    Pasqualin, Matteo

    2013-01-01

    Since the early 80’s the forward steps in genetics and proteomics, have led a particular interest to biotech products, such as DNA and proteins. Although difficult, their large-scale production enabled the therapeutic use of this compounds. Proteins and DNA sequences can be very interesting therapeutic molecules owing to their high selectivity/affinity for the receptor or the specific site of action. Unfortunately, some issues still limit their pharmaceutical use, such as the susceptibilit...

  2. The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008

    OpenAIRE

    Gaston Heimeriks; Ron Boschma

    2012-01-01

    This study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986-2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new cognitive developments within this scientific field. Our analyses show that biotech is subject to a path- and place-dependent process of knowledge production. We observed a high degree of re-occurrences of...

  3. Weizmann ties with Cambridge in physics contest

    CERN Multimedia

    Siegel, J

    2004-01-01

    "Scientists and students from the Weizmann Institute of Science in Rehovot and Cambridge University in England have tied for first place in a physics competition aimed at simulating the future functioning of the particle accelerator being built at the European center CERN and due to open in 2007" (1/2 page)

  4. Social Network Analysis of the Irish Biotech Industry: Implications for Digital Ecosystems

    Science.gov (United States)

    van Egeraat, Chris; Curran, Declan

    This paper presents an analysis of the socio-spatial structures of innovation, collaboration and knowledge flow among SMEs in the Irish biotech sector. The study applies social network analysis to determine the structure of networks of company directors and inventors in the biotech sector. In addition, the article discusses the implications of the findings for the role and contours of a biotech digital ecosystem. To distil these lessons, the research team organised a seminar which was attended by representatives of biotech actors and experts.

  5. University of Cambridge and MIT: Exploring Strategies for Digital Preservation for DSpace@Cambridge

    OpenAIRE

    Downing, Jim; Carpenter, Grace

    2005-01-01

    Cambridge University Library and MIT Libraries submit this proposal to share the outcomes of the digital preservation research work conducted through the DSpace@Cambridge project, concentrating on two main areas: Process Automation and Preservation Planning. Automation Digital preservation activity in its current form commonly involves a high level of human effort. In mediated archiving the archivist's efforts do not scale well. In self-archiving situations this effort can be a barri...

  6. Deutsche Biotech-Unternehmen und ihre Innovationsfähigkeit im internationalen Vergleich : eine institutionentheoretische Analyse

    NARCIS (Netherlands)

    Lange, K.S.G.

    2006-01-01

    German Biotech-Companies and their Innovativeness in International Comparison – an Institutionalist Analysis 1 Introduction In the mid-1990s, legal changes and policy initiatives in Germany led to the rapid emergence of a biotechnology industry. Initially, German biotech companies focused on the mar

  7. Alchemy in Cambridge. An Annotated Catalogue of Alchemical Texts and Illustrations in Cambridge Repositories.

    Science.gov (United States)

    Timmermann, Anke

    2015-01-01

    Alchemy in Cambridge captures the alchemical content of 56 manuscripts in Cambridge, in particular the libraries of Trinity College, Corpus Christi College and St John's College, the University Library and the Fitzwilliam Museum. As such, this catalogue makes visible a large number of previously unknown or obscured alchemica. While extant bibliographies, including those by M.R. James a century ago, were compiled by polymathic bibliographers for a wide audience of researchers, Alchemy in Cambridge benefits from the substantial developments in the history of alchemy, bibliography, and related scholarship in recent decades. Many texts are here identified for the first time. Another vital feature is the incorporation of information on alchemical illustrations in the manuscripts, intended to facilitate research on the visual culture of alchemy. The catalogue is aimed at historians of alchemy and science, and of high interest to manuscript scholars, historians of art and historians of college and university libraries. PMID:26245008

  8. Cambridge IGCSE english as a second language

    CERN Document Server

    Reynolds, John

    2014-01-01

    Revised edition for the 2015 syllabus offering the easiest and most cost effective way to teach both the speaking and listening components with one set of books covering two years and free digital material. This title has been written for the revised Cambridge IGCSE English as a Second Language (0510 and 0511) syllabuses, for first teaching from 2013. ? Prepares students for their exams with a focus on assessed language features, such as inference, opinion and attitude. ? Develops language abilities at an appropriate pace with extra interactive tests on a free CD-ROM. We are working with Cambr

  9. The Cambridge Guide to the Solar System

    Science.gov (United States)

    Lang, Kenneth R.

    2003-10-01

    The Cambridge Guide to the Solar System provides a comprehensive, funamental, and up-to-date description of the solar system. It is written in a concise, light and uniform style, without being unnecessarily weighted down with specialized materials or the variable writing of multiple authors. It is filled with vital facts and information for astronomers of all types and for anyone with a scientific interest in the Earth, our Moon, all the other planets and their satellites, and related topics such as asteroids, comets, meteorites and meteors. The language, style, ideas and profuse illustrations will attract the general reader as well as professionals. A thorough report for general readers, it includes much compact reference data. Metaphors, similes and analogies will be of immense help to the lay person or non-science student, and they add to the enjoyment of the material. Vignettes containing historical, literary and even artistic material make this book unusual and interesting, and enhance its scientific content. Kenneth Lang is professor of astronomy in the Physics and Astronomy Department at Tufts University. He is the author of several astrophysics books, including The Sun from Space (Springer Verlag, 2000), Astrophysical Formulae: Radiation, Gas Processes, and High Energy Physics (Springer Verlag, 1999), Sun, Earth and Sky (Copernicus Books, 1997), Astrophysical Data: Planets and Stars (Springer Verlag, 1993), and Wanderers in Space: Exploration and Discovery in the Solar System (Cambridge, 1991),

  10. Can science be a business? Lessons from biotech.

    Science.gov (United States)

    Pisano, Gary P

    2006-10-01

    In 1976, Genentech, the first biotechnology company, was founded by a young venture capitalist and a university professor to exploit recombinant DNA technology. Thirty years and more than 300 billion dollars in investments later, only a handful of biotech firms have matched Genentech's success or even shown a profit. No avalanche of new drugs has hit the market, and the long-awaited breakthrough in R&D productivity has yet to materialize. This disappointing performance raises a question: Can organizations motivated by the need to make profits and please shareholders successfully conduct basic scientific research as a core activity? The question has largely been ignored, despite intense debate over whether business's invasion of basic science-long the domain of universities and nonprofit research institutions- is limiting access to discoveries, thereby slowing advances in science. Biotech has not lived up to its promise, says the author, because its anatomy, which has worked well in other high-tech sectors, can't handle the fundamental challenges facing drug R&D: profound, persistent uncertainty and high risks rooted in the limited knowledge of human biology; the need for the diverse disciplines involved in drug discovery to work together in an integrated fashion; and barriers to learning, including tacit knowledge and murky intellectual property rights, which can slow the pace of scientific advance. A more suitable anatomy would include increased vertical integration; a smaller number of closer, longer collaborations; an emphasis by universities on sharing rather than patenting scientific discoveries; more cross-disciplinary academic research; and more federal and private funding for translational research, which bridges basic and applied science. With such modifications, science can be a business. PMID:17040044

  11. 77 FR 10598 - BIOTECH Holdings Ltd., California Oil & Gas Corp., Central Minera Corp., Chemokine Therapeutics...

    Science.gov (United States)

    2012-02-22

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION BIOTECH Holdings Ltd., California Oil & Gas Corp., Central Minera Corp., Chemokine Therapeutics... current and accurate information concerning the securities of California Oil & Gas Corp. because it...

  12. The Whipple Museum and Cavendish Laboratory, Cambridge

    Science.gov (United States)

    Pippard, Brian

    The Whipple Museum is part of the History and Philosophy of Science Department in the University of Cambridge. It is on your right as soon as you enter Free School Lane from Pembroke Street, and is normally open between 1:30 and 4:30 P.M. on weekdays. The main room, a hall with hammer-beam roof, is a relic of Stephen Perse’s school (1624) now flourishing elsewhere in the city. It houses a large collection of mathematical, physical and astronomical instruments — abaci, Napier’s bones, slide rules; sextants and other surveying instruments; telescopes, compasses and pocket sundials (especially of ivory from Nuremberg 1500-1700); and a Grand Orrery by George Adams (1750). The gallery of a second room is used for special exhibitions, often of items from the well-stocked store. Some specialist catalogues have been compiled and are on sale.

  13. Deutsche Biotech-Unternehmen und ihre Innovationsfähigkeit im internationalen Vergleich: eine institutionentheoretische Analyse

    OpenAIRE

    Lange, K.S.G.

    2006-01-01

    German Biotech-Companies and their Innovativeness in International Comparison – an Institutionalist Analysis 1 Introduction In the mid-1990s, legal changes and policy initiatives in Germany led to the rapid emergence of a biotechnology industry. Initially, German biotech companies focused on the market segment of platform technologies, characterized by incremental innovations. In recent years however, many companies have shifted their strategic focus on the market segment of therapeutics, cha...

  14. Exploiting the business opportunities in biotech connections : The power of social networks

    OpenAIRE

    Salehi-Sangari, Esmail

    2007-01-01

    Networks have a well-established importance in business. Here network analysis, grounded in socialnetwork theory, is used to analyse two international biotech business-to-business environments. Ofadditional value, the methodology employed is described for the benefi t of academics and practitionersalike. Swedish and Australian biotech fi rms are analysed through the examination of internet networks.Once gathered and analysed following the described methodology, several features of the networks ...

  15. Cambridge Illustrated History of Archaeology, edited by Paul G. Bahn, Cambridge University Press, New York, 1996

    OpenAIRE

    Douglas R. Givens

    1997-01-01

    The Cambridge Illustrated History of Archaeology is another in a series of volumes devoted to the history of archaeology that have appeared in recent time. Paul Bahn, the editor of the volume, has broken down his coverage of the history of worldwide archaeology into the following arrangement 'The Archaeology of Archaeology", "Old Worlds and New, 1500-1760", "Antiquarians and Explorers, 1760-1820", "Science and Romantic...

  16. Teachers Learning: Professional Development and Education. Cambridge Education Research Series

    Science.gov (United States)

    McLaughlin, Colleen, Ed.

    2012-01-01

    "Teachers Learning: Professional Development and Education" is part of The Cambridge Education Research series, edited by senior colleagues at the University of Cambridge Faculty of Education, which has a longstanding tradition of involvement in high quality, innovative teacher education and continuing professional development.…

  17. Social Network Analysis of the Irish Biotech Industry: Implications for Digital Ecosystems (NIRSA) Working Paper Series No. 55.

    OpenAIRE

    Van Egeraat, Chris; Curran, Declan

    2010-01-01

    This paper presents an analysis of the socio-spatial structures of innovation, collaboration and knowledge flow among SMEs in the Irish biotech sector. The study applies social network analysis to determine the structure of networks of company directors and inventors in the biotech sector. In addition, the article discusses the implications of the findings for the role and contours of a biotech digital ecosystem. To distil these lessons, the research team organised a seminar which was attende...

  18. The Swiss biotech referendum: A case study of science communication

    International Nuclear Information System (INIS)

    On June 7 , 1998, the Swiss citizens voted on a constitutional amendment, which could have jeopardised the future of biotechnological research in Switzerland. Scientists and opinion leaders around the world expected the referendum with great anxiety. 'Nature', in an editorial, had firmly stated that the Swiss way showed 'how not to run a country', the 'Economist', a week prior to the referendum, had written that the Swiss might be the only people in the world who decided on their own to forego a world class position in scientific research. In fact, the Swiss did none of that. They rejected the constitutional amendment with an overwhelming majority of 67 per cent of the votes, and what started out as a dramatic threat to scientific research in Switzerland became a platform in favour of modern biotechnology. The presentation addresses some of the key features of the Swiss biotech campaign, analyses the success factors of the campaign, provides an insight in the most in-depth collection of data on public perception of biotechnology in the world, and draws conclusions as to what extent the Swiss experience can be of use in the way to communicate on modem science. The result of the Swiss referendum has convincingly shown that successful communication of modem science is possible if - scientists, authorities, and the industry accept the challenge to cope with the demands of communicating with the public at large, - there is a clear understanding that the public's needs may often be based on psychological rather than on logic scientific reasons, - all participants in the dialogue are willing to forego scientific jargon for clear understandable language, i.e. understand that it is hardly the public's fault if messages do not get across, - everybody accepts that dialogue, information, and education on modem science is a long-haul task. The Swiss biotech referendum was seen as a major threat to Switzerland as a leading country of scientific research. However, something which

  19. The CAMbridge Emission Line Surveyor (CAMELS)

    CERN Document Server

    Thomas, C N; Maiolino, R; Goldie, D J; Acedo, E de Lera; Wagg, J; Blundell, R; Paine, S; Zeng, L

    2014-01-01

    The CAMbridge Emission Line Surveyor (CAMELS) is a pathfinder program to demonstrate on-chip spectrometry at millimetre wavelengths. CAMELS will observe at frequencies from 103-114.7 GHz, providing 512 channels with a spectral resolution of R = 3000. In this paper we describe the science goals of CAMELS, the current system level design for the instrument and the work we are doing on the detailed designs of the individual components. In addition, we will discuss our efforts to understand the impact that the design and calibration of the filter bank on astronomical performance. The shape of the filter channels, the degree of overlap and the nature of the noise all effect how well the parameters of a spectral line can be recovered. We have developed a new and rigorous method for analysing performance, based on the concept of Fisher information. This can in be turn coupled to a detailed model of the science case, allowing design trade-offs to be properly investigated.

  20. Recent Developments in Cambridge College Libraries

    Directory of Open Access Journals (Sweden)

    Alison Wilson

    2006-07-01

    Full Text Available Cambridge University has three tiers of libraries available to students: the University Library, departmental (subject libraries and college libraries. Over the past thirty years there has been increasing pressure on the colleges to provide more books, reader places and technical resources in their libraries, with the result that a number of new library buildings, of very different styles, have been opened. Other colleges have opted for refurbishment and extension of existing libraries. These libraries are small (30-100,000 books and intimate, often open 24 hours a day and with generous provision for lending books. Great importance is placed on keeping them at the heart of the college. Challenges for architects are the sensitive sites, restrictions on changes to listed buildings, and the limited space available. The constricted sites cause difficulties for the builders too. I will consider some solutions to these problems with reference to projects in four colleges: Pembroke, Peterhouse, Corpus Christi and Newnham. At Pembroke architects Freeland Rees Roberts have built an extension to a listed building and at Peterhouse they have adapted an adjoining room. Corpus Christi is moving its library to a Victorian building which has been internally redesigned by Wright + Wright. Newnham demolished a 1960s extension in order to develop the plot more efficiently to a design by John Miller + Partners. All the architects have shown sensitivity to the needs of their clients and ingenuity in making intensive use of limited space.

  1. 3D-BioPrinting: The future of Red Biotech

    International Nuclear Information System (INIS)

    Every day Science moves little steps forward, contributing to the progress of our society. Sometimes, however, a single invention revolutionizes the world. Indeed, the invention of woodblock printing and development of industrial-scale printing-press in the 15. century have changed our society. 3D-printing is now boosting another revolution. The production of custom-made objects from a virtual model will trigger a rapid development of a more versatile, less expensive manufacturing sector for the on-demand market. The real revolution, however, is represented by 3D-printing in biomedicine. 3D-bioprinting represents the future of the Red-Biotech. This technology, indeed, will be able to build ex-novo organs using biocompatible materials and human cells; replace the allograft transplants, eliminating waiting lists that often make the difference between life and death; and provide more predictive, less expensive experimental models, replacing animal tests. The high innovation content of this technology, can make the difference between being obsolete and new

  2. Cohort profile: the Cambridge Baby Growth Study (CBGS)

    OpenAIRE

    Prentice, P.; Acerini, C. L.; Eleftheriou, A.; Hughes, I A; Ong, K K; Dunger, D B

    2015-01-01

    The Cambridge Baby Growth Study has been supported by the European Union Framework V, the World Cancer Research Foundation International, the Medical Research Council, the NIHR Cambridge Comprehensive Biomedical Research Centre, the Newlife Foundation for disabled children, the Mothercare Group Foundation, Mead Johnson Nutrition, the Evelyn Trust, the Wellbeing of Women, Diabetes UK and a collaborative research grant from the European Society for Paediatric Endocrinology.

  3. Trends in global approvals of biotech crops (1992-2014).

    Science.gov (United States)

    Aldemita, Rhodora R; Reaño, Ian Mari E; Solis, Renando O; Hautea, Randy A

    2015-01-01

    With the increasing number of genetically modified (GM) events, traits, and crops that are developed to benefit the global population, approval of these technologies for food, feed, cultivation and import in each country may vary depending on needs, demand and trade interest. ISAAA established a GMO Approval Database to document global approvals of biotech crops. GM event name, crops, traits, developer, year of approval for cultivation, food/feed, import, and relevant dossiers were sourced from credible government regulatory websites and biosafety clearinghouses. This paper investigates the trends in GM approvals for food, feed and cultivation based on the number of approving countries, GM crops, events, and traits in the last 23 y (1992-2014), rationale for approval, factors influencing approvals, and their implications in GM crop adoption. Results show that in 2014, there was an accumulative increase in the number of countries granting approvals at 29 (79% developing countries) for commercial cultivation and 31 (70% developing countries) for food and 19 (80% developing developing) for feed; 2012 had the highest number of approving countries and cultivation approvals; 2011 had the highest number of country approvals for feed, and 2014 for food approvals. Herbicide tolerance trait had the highest events approved, followed by insect tolerance traits. Approvals for food product quality increased in the second decade. Maize had the highest number of events approved (single and stacked traits), and stacked traits product gradually increased which is already 30% of the total trait approvals. These results may indicate understanding and acceptance of countries to enhance regulatory capability to be able to benefit from GM crop commercialization. Hence, the paper provided information on the trends on the growth of the GM crop industry in the last 23 y which may be vital in predicting future GM crops and traits. PMID:26039675

  4. Where is the biotech industry in China headed to?%中国生物技术产生的发展方向

    Institute of Scientific and Technical Information of China (English)

    苏慰国

    2009-01-01

    @@ 2008 was a year marked with changes and turns for biotech industry in China. 2008 began with tremendous promises riding on the waves of a history-making, exceptionally strong year in 2007. However, the biotech industry in China was not immune to the macroeconomic changes during 2008. This report will attempt to examine changes and new trends in biotech industry in China.

  5. Detection methods for biotech cotton MON 15985 and MON 88913 by PCR.

    Science.gov (United States)

    Lee, Seong-Hun; Kim, Jin-Kug; Yi, Bu-Young

    2007-05-01

    Plants derived through agricultural biotechnology, or genetically modified organisms (GMOs), may affect human health and ecological environment. A living GMO is also called a living modified organism (LMO). Biotech cotton is a GMO in food or feed and also an LMO in the environment. Recently, two varieties of biotech cotton, MON 15985 and MON 88913, were developed by Monsanto Co. The detection method is an essential element for the GMO labeling system or LMO management of biotech plants. In this paper, two primer pairs and probes were designed for specific amplification of 116 and 120 bp PCR products from MON 15985 and MON 88913, respectively, with no amplification from any other biotech cotton. Limits of detection of the qualitative method were all 0.05% for MON 15985 and MON 88913. The quantitative method was developed using a TaqMan real-time PCR. A synthetic plasmid, as a reference molecule, was constructed from a taxon-specific DNA sequence of cotton and two construct-specific DNA sequences of MON 15985 and MON 88913. The quantitative method was validated using six samples that contained levels of biotech cotton mixed with conventional cotton ranging from 0.1 to 10.0%. As a result, the biases from the true value and the relative deviations were all within the range of +/-20%. Limits of quantitation of the quantitative method were all 0.1%. Consequently, it is reported that the proposed detection methods were applicable for qualitative and quantitative analyses for biotech cotton MON 15985 and MON 88913. PMID:17402745

  6. Parameters of Regional Cooperative Behavior in the German Biotech Industry – A Quantitative Social Network Analysis

    DEFF Research Database (Denmark)

    Mitze, Timo; Strotebeck, Falk

    We analyse the determinants of network formation in Germany’s biotechnology industry using social network analysis combined with a regression approach for count data. Outcome variable of interest is the degree centrality of German regions, which is specified as a function of the region’s innovative...... and economic performance as well as biotech-related policy variables. The inclusion of the latter allows us to shed new light on the question to what extent R&D-based cluster policies are able to impact on the formation of the German biotech network. Our results show that policy indicators such as the...... the German biotechnology network....

  7. Michele Renee Salzman, Marvina A. Sweeney & William Adler (eds., The Cambridge History of Religions in the Ancient World (2 vols. (New York: Cambridge University Press, 2013

    Directory of Open Access Journals (Sweden)

    Giorgio Baruchello

    2014-03-01

    Full Text Available Review of: Michele Renee Salzman, Marvina A. Sweeney & William Adler (eds., The Cambridge History of Religions in the Ancient World (2 vols. (New York: Cambridge University Press, 2013

  8. How Is Corporate Social Responsibility Addressed by Biotech Firms? a Case Study Analysis

    Science.gov (United States)

    Pérez-Bustamante, Guillermo

    2013-01-01

    This paper explores corporate social responsibility (CSR) in the biotech high-tech sector as a way to achieve competitive advantages. After presenting the importance of science for high-tech firms, the paper focuses on the social and economic role of CSR. Next, the primary reasons for firms' engagement in CSR activities are presented,…

  9. The industrial application requirement for biotech inventions in light of recent EPO & UK case law:

    DEFF Research Database (Denmark)

    Minssen, Timo; Nilsson, David

    2012-01-01

    at the date of filing to demonstrate a credible – or to use the terminology of the EPO – a plausible industrial application. In the final section of the article we shall also discuss various policy considerations relevant for the biotech industry and briefly refer to corresponding developments in the US...

  10. Biotech/GM crops in horticulture: plum cv. HoneySweet resistant to plum pox virus

    Science.gov (United States)

    Commercialization of Biotech crops started in 1995. By 2011, genetically modified (GM) crops were grown world-wide on 160 million ha. Only 114.507 ha of GM crops were grown in Europe, of that, 114.490 ha were Bt maize and 17 ha were potato for industrial starch production. Currently, developing c...

  11. 77 FR 14852 - Advanced Growing Systems, Inc., Advantage Capital Development Corp., Amazon Biotech, Inc...

    Science.gov (United States)

    2012-03-13

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Advanced Growing Systems, Inc., Advantage Capital Development Corp., Amazon Biotech, Inc., Andover... securities of Advantage Capital Development Corp. because it has not filed any periodic reports since...

  12. 76 FR 42682 - China Biotech Life Sciences Trade Mission-Clarification and Amendment

    Science.gov (United States)

    2011-07-19

    ... publishing this supplement to the Notice of the Biotech Life Science Trade Mission to China, 76 FR 17,621... and life science firms and trade organizations. In response to various inquiries, CS is clarifying...), interested U.S. biotechnology and life science firms and trade organizations which have not already...

  13. 8th Cambridge Workshop on Universal Access and Assistive Technology

    CERN Document Server

    Lazar, Jonathan; Heylighen, Ann; Dong, Hua

    2016-01-01

    This book presents the proceedings of the 8th Cambridge Workshop on Universal Access and Assistive Technology (CWUAAT '14), incorporating the 11th Cambridge Workshop on Rehabilitation Robotics, held in Cambridge, England in March 2016. It presents novel and state-of-the-art research from an international group of leaders in the fields of universal access and assistive technology. It explores various issues including the reconciliation of usability, accessibility and inclusive design, the design of inclusive assistive and rehabilitation systems, measuring product demand and human capabilities, data mining and visualizing inclusion, legislation in inclusive design, and situational inclusive interfaces (automotive and aerospace). This book provides an invaluable resource to researchers, postgraduates, design practitioners, therapists and clinical practitioners, as well as design teachers.

  14. Cambridge international AS and A level mathematics mechanics

    CERN Document Server

    Porkess, Roger

    2012-01-01

    This brand new series has been written for the University of Cambridge International Examinations course for AS and A Level Mathematics (9709). This title covers the requirements of M1 and M2. The authors are experienced examiners and teachers who have written extensively at this level, so have ensured all mathematical concepts are explained using language and terminology that is appropriate for students across the world. Students are provded with clear and detailed worked examples and questions from Cambridge International past papers, so they have the opportunity for plenty of essential exam

  15. Cambridge international AS and A level mathematics statistics

    CERN Document Server

    Porkess, Roger; Konrad, Nina

    2012-01-01

    This brand new series has been written for the University of Cambridge International Examinations course for AS and A Level Mathematics (9709). This title covers the requirements of S1 and S2. The authors are experienced examiners and teachers who have written extensively at this level, so have ensured all mathematical concepts are explained using language and terminology that is appropriate for students across the world. Students are provded with clear and detailed worked examples and questions from Cambridge International past papers, so they have the opportunity for plenty of essenti

  16. Cambridge Illustrated History of Archaeology, edited by Paul G. Bahn, Cambridge University Press, New York, 1996

    Directory of Open Access Journals (Sweden)

    Douglas R. Givens

    1997-11-01

    Full Text Available The Cambridge Illustrated History of Archaeology is another in a series of volumes devoted to the history of archaeology that have appeared in recent time. Paul Bahn, the editor of the volume, has broken down his coverage of the history of worldwide archaeology into the following arrangement 'The Archaeology of Archaeology", "Old Worlds and New, 1500-1760", "Antiquarians and Explorers, 1760-1820", "Science and Romanticism, 1820-1860", "The Search for Human Origins, 1860-1920", "Archaeology Comes of Age, 1920-1960", "New Techniques and Competing Philosophies, 1960-1990",and "Current Controversies and Future Trends". Bahn's volume explores many of the major developments in archaeological practice from both in the classical world and was as from the practice of archaeology in the Americas. The volume even gives the reader a glimpse into the origins and growth of archaeology in New Zealand. Of particular interest is coverage of the history of early archaeological efforts having to do with early studies of human origins.

  17. Performance modelling of the Cambridge Fast Ring protocol

    NARCIS (Netherlands)

    Zafirovic-Vukotic, M.; Niemegeers, I.G.

    1988-01-01

    The Cambridge Fast Ring is high-speed slotted ring. The features that make it suitable for use at very large transmission rates are the synchronous transmission, the simplicity of the medium-access-control protocol, and the possibility of immediate retransmission of erroneous packets. A novel analyt

  18. Equipment and research outputs sharing at the University of Cambridge

    OpenAIRE

    Wilkinson, Christopher; Teperek, Marta

    2016-01-01

    Presentation delivered by Chris Wilkinson and Marta Teperek on 10 March 2016 about: The Equipment Sharing Project and the Equipment Database The importance of Open Access and of sharing publications and research data Services available to researchers at Cambridge enabling them to find and use shared equipment and to help them manage and share their research.

  19. Knowledge management in the QbD paradigm: manufacturing of biotech therapeutics.

    Science.gov (United States)

    Herwig, Christoph; Garcia-Aponte, Oscar F; Golabgir, Aydin; Rathore, Anurag S

    2015-07-01

    In the quality by design (QbD) paradigm, global regulatory agencies have introduced the concepts of quality risk management and knowledge management (KM) as enablers for an enhanced pharmaceutical quality system. Although the concept of quality risk management has been well elucidated in the literature, the topic of KM has received relatively scant attention. In this paper we present an opinion on KM in the QbD paradigm as it relates to the manufacturing of biotech therapeutic products. Both academic and industrial viewpoints have been considered and key gaps have been elucidated. The authors conclude that there is an urgent need for the biotech industry to create efficient KM approaches if they wish to be successful in QbD implementation. PMID:25980924

  20. The written description rejection as a barrier to biotech patent prosecution.

    Science.gov (United States)

    Wang, Shyh-Jen

    2011-05-01

    Biotech firms always pursue broad claims to secure new discoveries, new technologies and even as yet undiscovered results of future research. However, expansive claims without sufficient description violate the principal of granting the patentee the right to exclude others from using the technical development for a certain amount of time in return for disclosing the innovation. Based on this investigation, a written description can be a barrier to biotech patents with broad claims. To avoid a written description rejection during patent prosecution or invalidation in litigation, the patent applicant or assignee should demonstrate possession of the claimed invention by describing the claimed invention with all of its limitations using descriptive means such as words, structures, figures, diagrams, and formulas that fully set forth the claimed invention. Although the court cases analyzed in this study were not directly related to vaccines, the guideline indeed is applicable to patents of vaccine. Furthermore, a vaccine patent application is also demonstrated. PMID:21552000

  1. The Effects of Information on Consumer Demand for Biotech Foods: Evidence from Experimental Auctions

    OpenAIRE

    Tegene, Abebayehu; Huffman, Wallace E; Rousu, Matthew C.; Shogren, Jason F.

    2003-01-01

    Consumers' willingness to pay for food products decreases when the food label indicates that a food product is produced with the aid of modern biotechnology. This bulletin presents empirical evidence on consumers' willingness to pay for biotech foods based on the presence or absence of labels advising that the food was prepared with the aid of biotechnology. The authors designed and conducted an experimental auction to elicit consumers' willingness to pay for "genetically modified" (GM)-label...

  2. The Strategic Importance of M&A in the Biotech and Pharmaceutical Industry

    OpenAIRE

    Desai, Savri

    2011-01-01

    Background: The companies involved for the purpose of improving their respective market standings and income executes mergers. It is interesting how this merger & acquisition phenomena continue to attract many organizations across different sectors of the business world. The mergers & acquisition culture around the globe provides an ideal scenario to investigate into the healthcare industry which comprises of pharmaceutical and biotech companies and the impact of the mergers on the firms inv...

  3. Which Model of Technology Transfer for Nanotechnology? A Comparison with Biotech and Microelectronics

    OpenAIRE

    Genet, Corine; Errabi, Khalid; Gauthier, Caroline

    2012-01-01

    International audience Nanotechnologies are often presented as breakthrough innovations, where technology transfer and knowledge-bridging will play a pivotal role in the industrial dynamics. This article investigates the model of knowledge transfer in the nanotechnologies in depth, by comparing it with the models of two recently emerged technologies: biotech and microelectronics. Our results show that the nanotechnology transfer model is very different from that involved in biotechnology e...

  4. Simplex and duplex event-specific analytical methods for functional biotech maize.

    Science.gov (United States)

    Lee, Seong-Hun; Kim, Su-Jeong; Yi, Bu-Young

    2009-08-26

    Analytical methods are very important in the control of genetically modified organism (GMO) labeling systems or living modified organism (LMO) management for biotech crops. Event-specific primers and probes were developed for qualitative and quantitative analysis for biotech maize event 3272 and LY 038 on the basis of the 3' flanking regions, respectively. The qualitative primers confirmed the specificity by a single PCR product and sensitivity to 0.05% as a limit of detection (LOD). Simplex and duplex quantitative methods were also developed using TaqMan real-time PCR. One synthetic plasmid was constructed from two taxon-specific DNA sequences of maize and two event-specific 3' flanking DNA sequences of event 3272 and LY 038 as reference molecules. In-house validation of the quantitative methods was performed using six levels of mixing samples, from 0.1 to 10.0%. As a result, the biases from the true value and the relative deviations were all within the range of +/-30%. Limits of quantitation (LOQs) of the quantitative methods were all 0.1% for simplex real-time PCRs of event 3272 and LY 038 and 0.5% for duplex real-time PCR of LY 038. This study reports that event-specific analytical methods were applicable for qualitative and quantitative analysis for biotech maize event 3272 and LY 038. PMID:19650633

  5. Bookreview: A movable feast: ten millennia of food globalization. By Kenneth F. Kiple. Cambridge: Cambridge University Press. 2007. xvi + 364 pp. £15.99 hardback. ISBN 9780521793537

    OpenAIRE

    Hallett, Lucius

    2008-01-01

    520BookreviewAmovable feast: ten millennia of food globalization. By Kenneth F. Kiple. Cambridge:Cambridge University Press. 2007. xvi + 364 pp. £15.99 hardback. ISBN 9780521793537SAGE Publications, Inc.2008DOI: 10.1177/14744740080150040703LuciusHallettUniversity of WyomingBasedlargely upon the author's The Cambridge world history of food (2000), thisbook offers an overview of the interaction between the world and the foodswe currently consume. Reviewing the history of domestication, sedentis...

  6. New software for statistical analysis of Cambridge Structural Database data

    OpenAIRE

    Sykes, Richard A.; McCabe, Patrick; Allen, Frank H; Battle, Gary M.; Bruno, Ian J.; Wood, Peter A.

    2011-01-01

    A collection of new software tools is presented for the analysis of geometrical, chemical and crystallographic data from the Cambridge Structural Database (CSD). This software supersedes the program Vista. The new functionality is integrated into the program Mercury in order to provide statistical, charting and plotting options alongside three-dimensional structural visualization and analysis. The integration also permits immediate access to other information about specific CSD entries throug...

  7. Metaphor Analysis of Chinese Premier Wen’s Cambridge Speech

    Institute of Scientific and Technical Information of China (English)

    LUO Luo

    2014-01-01

    Metaphor is more than an ostensible decoration of language. It is an integral part of human thought of ideologized world. This article analyzes the metaphor use of Chinese Premier Wen Jiabao’s speech at Cambridge in February 2009, in an at-tempt to display how the preferred metaphors serve the purpose of this speech and reflect Premier Wen ’s construction of Chi-na’s situation.

  8. The competition for the Woodwardian Chair of Geology, Cambridge 1873.

    OpenAIRE

    O'Connor, A

    2005-01-01

    In 1873 the chair of geology at the University of Cambridge fell vacant following the death of Adam Sedgwick. Nine candidates stepped forward, hoping to fill the post. The correspondence generated in the ensuing battle illuminates two areas of particular interest. First, the strategies hidden behind bland lists of successive professors: candidates, peers and patrons manoeuvred to influence the outcome of the competition and competitors tried to reinforce their geological respectability by col...

  9. University of Cambridge deploys Procket Networks' PRO/8801

    CERN Multimedia

    2003-01-01

    Procket Networks, a provider of high performance Internet Protocol (IP) technology and products has announced that the University of Cambridge has deployed the PRO/8801(TM) router into its research network to develop industry-leading deep packet inspection applications. The major application for this deployment is to identify and understand new traffic patterns created by large scale scientific computations and downloads such as the GRID (1 page).

  10. Philosophy at Cambridge, Newsletter of the Faculty of Philosophy

    OpenAIRE

    2008-01-01

    Philosophy Newsletter. Articles by: Edward Craig - From the Chairman. Onora O'Neill - "It's the newspapers I can't stand. Serena Olsaretti - The 2004 Annual Royal Institute of Philosophy Conference. Mary Leng - Mathematical Knowledge Conference. Postgraduate Conference. Jane Heal - Facts, Fables and Funds. Hugh Mellor - Uses and Abuses of Probability. Amanda Boyle - Nobody Knows Anything: Philosophy, Film and Me. Jaime Whyte - Seven Years at Cambridge Alex Oliver...

  11. Cambridge IGCSE and international certificate French foreign language

    CERN Document Server

    Grime, Yvette; Thacker, Mike

    2013-01-01

    This brand-new Student Book provides a grammar-led approach with extensive exam preparation that will help you develop independent, culturally aware students of French ready for the exam. The book is written to the latest Cambridge International Examinations syllabus by experienced teachers. Extensive use of French reflects the style of the exams and, with specific advice and practice, it helps students use the acquired skills to their best ability. Topics on Francophone cultures are integrated throughout to ensure students gain the cultural awareness that is at the heart of this qualification

  12. WORKING WITH ARCHIVES: CAMBRIDGE ECONOMICS THROUGH THE MAGNIFYING GLASS

    Directory of Open Access Journals (Sweden)

    Maria Cristina Marcuzzo

    2012-12-01

    Full Text Available Research in economics using documentary archives provides clearer interpretations about the ideas and their development throughout time, in the context of the writing process in relation to the interlocutors and antagonists, and the nature of the problems addressed. This document presents examples of works with tough drafts, correspondence, tables of contents, notes, and related material of four economists of the "Cambridge Group": Piero Sraffa, Richard Kahn, Joan Robinson, and John Maynard Keynes. In each case the findings and importance of the research done in the files are described.

  13. Does Cluster Policy Trigger R&D Activity? – Evidence from German Biotech Contests

    DEFF Research Database (Denmark)

    Engel, Dirk; Mitze, Timo; Patuelli, Roberto; Reinkowski, Janina

    in research clusters. We apply a Difference-in-Differences estimation technique in a generalized linear model framework, which allows us to control for different initial regional conditions in R&D activity of the biotech sector. Our econometric findings support the view that winners generally...... outperform non-winning participants during the treatment period, thus indicating that exclusive funding as well as the stimulating effect of being a “winner” have positive effects on R&D activity in the short-term. Apart from this direct winner effect, for the non-winning participants no beneficial indirect...

  14. Job Opportunities in Pharma and Biotech: What Makes a Future Employee Stand Out?

    OpenAIRE

    Mische, Sheenah

    2012-01-01

    These are turbulent times. For Pharma and Biotech there is the potential of new inventions and discovery tempered by the fact that it now takes an average of 12 to 15 years and up to $1.7 billion for a drug to go from discovery to market. Despite all the time and money invested, only a handful of drugs are approved by the FDA each year. The arduous drug approval process reveals a central fact about the pharmaceutical industry: it's one of the most intensely regulated industries in the world. ...

  15. Recombinant DNA in Cambridge: lessons for nuclear energy

    International Nuclear Information System (INIS)

    The 1976 experience of Cambridge, Massachusetts, in settling the recombinant DNA research issue is unique in recent history as the first instance of essentially lay panels judging the conduct of scientific research. Furthermore, because the panel was composed of citizens who would be affected by the research, the experience suggests a model for conflict resolution in other areas of public controversy. With one of these, nuclear energy, the controversy has two important points in common: although the primary burden of any accident would be borne by the local community, benefits of the DNA research or reactor operation accrue to a much broader range of people; and in both issues there is a need to resolve the question, ''How safe is safe enough.'' It is therefore proposed that a panel similar to the Cambridge one could be established to deal with the controversy surrounding a proposed nuclear plant. In any community where there was such controversy, a panel could be convened to assess whether the plant was acceptable to that community. Such a panel would be composed of members of the community who were not affected directly by the plant. It would also have to have a restricted range of inquiry, oriented toward the specifics of the proposed plant. Such a plant review panel, under properly designed procedures, could change the licensing process to one concerned solely with safety and provide an appropriate forum for issues concerning the acceptability of nuclear power

  16. The Cambridge Structural Database in retrospect and prospect.

    Science.gov (United States)

    Groom, Colin R; Allen, Frank H

    2014-01-13

    The Cambridge Crystallographic Data Centre (CCDC) was established in 1965 to record numerical, chemical and bibliographic data relating to published organic and metal-organic crystal structures. The Cambridge Structural Database (CSD) now stores data for nearly 700,000 structures and is a comprehensive and fully retrospective historical archive of small-molecule crystallography. Nearly 40,000 new structures are added each year. As X-ray crystallography celebrates its centenary as a subject, and the CCDC approaches its own 50th year, this article traces the origins of the CCDC as a publicly funded organization and its onward development into a self-financing charitable institution. Principally, however, we describe the growth of the CSD and its extensive associated software system, and summarize its impact and value as a basis for research in structural chemistry, materials science and the life sciences, including drug discovery and drug development. Finally, the article considers the CCDC's funding model in relation to open access and open data paradigms. PMID:24382699

  17. Applications of the Cambridge Structural Database in chemical education.

    Science.gov (United States)

    Battle, Gary M; Ferrence, Gregory M; Allen, Frank H

    2010-10-01

    The Cambridge Structural Database (CSD) is a vast and ever growing compendium of accurate three-dimensional structures that has massive chemical diversity across organic and metal-organic compounds. For these reasons, the CSD is finding significant uses in chemical education, and these applications are reviewed. As part of the teaching initiative of the Cambridge Crystallographic Data Centre (CCDC), a teaching subset of more than 500 CSD structures has been created that illustrate key chemical concepts, and a number of teaching modules have been devised that make use of this subset in a teaching environment. All of this material is freely available from the CCDC website, and the subset can be freely viewed and interrogated using WebCSD, an internet application for searching and displaying CSD information content. In some cases, however, the complete CSD System is required for specific educational applications, and some examples of these more extensive teaching modules are also discussed. The educational value of visualizing real three-dimensional structures, and of handling real experimental results, is stressed throughout. PMID:20877495

  18. Differences between software retailers from cambridge and braðsov regarding online marketing strategies

    OpenAIRE

    Boitor, Axenia Bianca; Bréatucu, Gabriel

    2013-01-01

    This paper presents an analysis and a comparison of the software traders' attitude from Bras,ov and Cambridge cities regarding the online promotion and marketing strategies used on the software market. Two surveys among traders in Cambridge and Bras,ov were performed and the results of the research emphasize a consistent difference between the software traders from Cambridge and those from Bras,ov. A large orientation to the e-commerce was discovered between the software retailers from Cambri...

  19. Capturing research outputs at the University of Cambridge : experiences with DSpace

    OpenAIRE

    Morgan, Peter

    2006-01-01

    This paper will report on two research projects at Cambridge University Library, one completed and the other still in progress, investigating the role of an institutional repository - using the DSpace software platform - to capture, disseminate and preserve research outputs at the University of Cambridge. The first project, DSpace@Cambridge (www.dspace.cam.ac.uk), ran from January 2003 to August 2006, and was a collaboration with MIT Libraries. Its initial objective was to establish and popul...

  20. 7th Cambridge Workshops on Universal Access and Assistive Technology

    CERN Document Server

    Lazar, J; Heylighen, A; Dong, H; Inclusive Designing : Joining Usability, Accessibility, and Inclusion

    2014-01-01

    ‘Inclusive Designing’ presents the proceedings of the seventh Cambridge Workshop on Universal Access and Assistive Technology (CWUAAT '14). It represents a unique multi-disciplinary workshop for the Inclusive Design Research community where designers, computer scientists, engineers, architects, ergonomists, policymakers and user communities can exchange ideas. The research presented at CWUAAT '14 develops methods, technologies, tools and guidance that support product designers and architects to design for the widest possible population for a given range of capabilities, within a contemporary social and economic context. In the context of developing demographic changes leading to greater numbers of older people and people with disabilities, the general field of Inclusive Design Research strives to relate the capabilities of the population to the design of products. Inclusive populations of older people contain a greater variation in sensory, cognitive and physical user capabilities. These variations may be...

  1. Traffic Sign Recognition System based on Cambridge Correlator Image Comparator

    Directory of Open Access Journals (Sweden)

    J. Turan

    2012-06-01

    Full Text Available Paper presents basic information about application of Optical Correlator (OC, specifically Cambridge Correlator, in system to recognize of traffic sign. Traffic Sign Recognition System consists of three main blocks, Preprocessing, Optical Correlator and Traffic Sign Identification. The Region of Interest (ROI is defined and chosen in preprocessing block and then goes to Optical Correlator, where is compared with database of Traffic Sign. Output of Optical Correlation is correlation plane, which consist of highly localized intensities, know as correlation peaks. The intensity of spots provides a measure of similarity and position of spots, how images (traffic signs are relatively aligned in the input scene. Several experiments have been done with proposed system and results and conclusion are discussed.

  2. Solid lipid nanoparticles for hydrophilic biotech drugs: optimization and cell viability studies (Caco-2 & HEPG-2 cell lines)

    Czech Academy of Sciences Publication Activity Database

    Severino, P.; Andreani, T.; Jäger, Alessandro; Chaud, M. V.; Santana, M. H. A.; Silva, A. M.; Souto, E. B.

    2014-01-01

    Roč. 81, 23 June (2014), s. 28-34. ISSN 0223-5234 R&D Projects: GA ČR GAP208/10/1600 Institutional support: RVO:61389013 Keywords : lipid nanoparticles * double emulsion * hydrophilic biotech drugs Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.447, year: 2014

  3. Pengaruh Kualitas Pelayanan terhadap Kepuasan Konsumen pada Cosa Nostra Bistro Cambridge Medan ( Study Pada Cosa Nostra Bistro Cambridge City Square, Medan)

    OpenAIRE

    Sihombing, Boy Martua

    2015-01-01

    This study entitled "The Effect of Service Quality on Customer Satisfaction in the Cosa Nostra Bistro Cambridge Field". This study aims to determine the effect of service quality indicators consisting of physical evidence, reliability, responsiveness, assurance, and empathy towards customer satisfaction on Cosa Nostra Bistro Cambridge Field. The theory used in this study is the theory related to service quality and customer satisfaction. The sample in this study as many as 90 people were t...

  4. Reflections on Cambridge: University examinations - how did they begin and how do they work?

    OpenAIRE

    Macfarlane, Alan

    2012-01-01

    Standing in one of the old examination halls in Cambridge, Alan Macfarlane talks about the invention of competitive university examinations (in mathematics in the earlier C19) and the central role of Cambridge as one of the biggest exam setting boards in the world. Also what Camrbdige examinations are thought to be testing.

  5. Worries of Pregnant Women: Testing the Farsi Cambridge Worry Scale

    Science.gov (United States)

    Mortazavi, Forough; Akaberi, Arash

    2016-01-01

    Pregnancy adds many sources of concerns to women's daily life worries. Excessive worry can affect maternal physiological and psychological state that influences the pregnancy outcomes. The aim of this study was to validate the Cambridge Worry Scale (CWS) in a sample of Iranian pregnant women. After translation of the CWS, ten experts evaluated the items and added six items to the 17-item scale. In a descriptive cross-sectional study, 405 of pregnant women booked for prenatal care completed the Farsi CWS. We split the sample randomly. Exploratory factor analysis (EFA) was conducted on the first half of the sample to disclose the factorial structure of the 23-item scale. The results of the EFA on the Farsi CWS indicated four factors altogether explained 51.5% of variances. Confirmatory factor analysis (CFA) was done on the second half of the sample. The results of the CFA showed that the model fit our data (chi-square/df = 2.02, RMSEA = 0.071, SRMR = 0.071, CFI = 0.95, and NNFI = 0.94). Cronbach's alpha coefficient for the Farsi CWS was 0.883. The Farsi CWS is a reliable and valid instrument for understanding common pregnancy worries in the third trimester of pregnancy in Iranian women. PMID:27293974

  6. Science communication in policy making:A qualitative research about the motivation of academic biotech scientists to participate in policy making in Europe

    OpenAIRE

    Coumou, Hilde; van der Werf Kulichova, Z.; Wehrmann, C.; Osseweijer, P.

    2014-01-01

    Policy making regarding application of agricultural biotechnology has been controversial. This study investigates what determines the motivation of European biotech scientists to actively participate in policy making. To do this, a conceptual framework was developed based on the Theory of Planned Behavior. The framework was operationalized in semi-structured interviews with 17 European biotech scientists to collect data about their motivation to involve in GMO policy making. The results of th...

  7. 40-Godišnjica institucije Cambridge Crystallographic Data Centre posvećene pohranjivanju podataka o molekularnim i kristalnim strukturama - "Cambridge Structural Database"

    OpenAIRE

    Kojić-Prodić, B.; Molčanov, K.

    2006-01-01

    U 2005. obilježila se 40-godišnjica postojanja i rada svjetski poznatog centra Cambridge Crystallographic Data Centre (CCDC), čija je temeljna svrha prikupljanje, provjera i čuvanje kristalografskih podataka koji uz bibliografske podatke sadrže i koordinate atoma i iona koji određuju trodimenzionalnu strukturu molekula u kristalu. Cambridge Structural Database (CSD), jedna od prvih elektroničkih baza podataka, najveća je i najznačajnija baza kristalografskih podataka na svijetu s gotovo 40...

  8. 40-godišnjica institucije Cambridge Crystallographic Data Centre namijenjene pohranjivanju podataka o molekularnim i kristalnim strukturama – “Cambridge Structural Database”

    OpenAIRE

    Kojić-Prodić, Biserka; Molčanov, Krešimir

    2006-01-01

    U 2005. obilježila se 40-godišnjica postojanja i rada svjetski poznatog centra Cambridge Crystallographic Data Centre (CCDC), čija je temeljna svrha prikupljanje, provjera i čuvanje kristalografskih podataka koji uz bibliografske podatke sadrže i koordinate atoma i iona koji određuju trodimenzionalnu strukturu molekula u kristalu. Cambridge Structural Database (CSD), jedna od prvih elektroničkih baza podataka, najveća je i najznačajnija baza kristalografskih podataka na svijetu...

  9. Research Data Services at Cambridge and our motivations for the Pilot

    OpenAIRE

    Teperek, Marta

    2016-01-01

    Presentation about Research Data Services at Cambridge and our perspective on Jisc RDM shared services pilot. Presentation given by Marta Teperek at IDCC16 on 22 February 2016, Amsterdam, Netherlands.

  10. Fiftieth Anniversary of the Cambridge Structural Database and Thirty Years of Its Use in Croatia

    OpenAIRE

    Kojić-Prodić B.; Molčanov K.

    2015-01-01

    This article is dedicated to the memory of Dr. F. H. Allen and the 50th anniversary of the Cambridge Crystallographic Data Centre (CCDC); the world-renowned centre for deposition and control of crystallographic data including atomic coordinates that define the three-dimensional structures of organic molecules and metal complexes containing organic ligands. The mission exposed at the web site (http://www.ccdc.cam.ac.uk) is clearly stated: “The Cambridge Crystallographic Data Centre (CCDC) is d...

  11. Advances in Treating Metastatic Bone Cancer: Summary Statement for the First Cambridge Conference

    OpenAIRE

    Lipton, Allan; Berenson, James R; Body, Jean-Jacques; Boyce, Brendan F.; Bruland, Oyvind S.; Carducci, Michael A; Cleeland, Charles S.; Clohisy, Denis R.; Coleman, Robert E.; Cook, Richard J.; Guise, Theresa A.; Pearse, Roger N.; Powles, Trevor J; Rogers, Michael J; Roodman, G. David

    2006-01-01

    The First Cambridge Conference on Advances in Treating Metastatic Bone Cancer, a symposium held in Cambridge, Massachusetts, October 28 to 29, 2005, was convened to discuss recent advances and research related to the natural history of bone metastases and skeletal complications, bone cancer biology, treatment of myeloma and other solid tumors, and treatment-induced bone loss. The conference format combined brief presentations with extended periods of discussion. The conclusions reached during...

  12. WebCSD: the online portal to the Cambridge Structural Database

    OpenAIRE

    Thomas, Ian R.; Bruno, Ian J.; Cole, Jason C; Macrae, Clare F.; Pidcock, Elna; Wood, Peter A.

    2010-01-01

    WebCSD, a new web-based application developed by the Cambridge Crystallographic Data Centre, offers fast searching of the Cambridge Structural Database using only a standard internet browser. Search facilities include two-dimensional substructure, molecular similarity, text/numeric and reduced cell searching. Text, chemical diagrams and three-dimensional structural information can all be studied in the results browser using the efficient entry summaries and embedded three-dimensional viewer.

  13. Trait stacking for biotech crops: an essential consideration for agbiotech development projects for building trust

    Directory of Open Access Journals (Sweden)

    Ezezika Obidimma C

    2012-05-01

    Full Text Available Abstract The development of agricultural biotechnology humanitarian projects for food security in the last five years has been rapid in developing countries and is expected to rise sharply over the coming years. An extremely critical issue in these projects involves building trust with the community and farmers they aim to serve. For the first time, our social audit engagement with one of these initiatives, the Water Efficient Maize for Africa project, has revealed that a critical but unrecognized component of building trust with farmers involves publicly addressing the concerns surrounding stacked trait crops. As a result, we argue in this article that it is critical to actively anticipate the concerns that could be raised over trait stacking by incorporating them into global access plans of such initiatives early in order to facilitate adoption, provide the best value to the small-scale farmer and gain trust with the community whom these projects aim to serve. This perspective, based on an actual international social audit, should be of value to scientists, funders and partners involved in biotech development initiatives for food security.

  14. Biotech outsourcing strategies cmc--biologics stream. June 17, 2010, Copenhagen, Denmark.

    Science.gov (United States)

    Hamer, Kate

    2010-01-01

    Now in its third year, the Biotech Outsourcing Strategies (BOS) meeting organized by Bio2Business took place at the Søhuset Conference Centre in Hørsholm, Copenhagen. The focus of this year's event was the demanding and challenging area of chemistry, manufacturing and controls (CMC), and the meeting provided ample opportunity for lively discussion of the key issues surrounding this area. New for the 2010 conference, a biologics-focused lecture stream ran in parallel to the established small molecule stream. Both streams boasted a distinguished panel of keynote speakers who discussed all aspects of CMC from early stage scale-up through late stage clinical development. In addition to the keynote speakers, selected contract research organizations (CROs) gave short presentations on the solutions that they could provide to some of the challenges facing CMC. The meeting attracted more than 150 delegates from leading drug development companies and CRO service providers, and greatly facilitated the forging of new working relationships through pre-arranged one-to-one meetings. Moreover, exhibitions from event sponsors and considerable scheduled networking time over lunch and evening reception further enhanced the highly productive and interactive nature of the meeting. PMID:20716956

  15. Next biotech plants: new traits, crops, developers and technologies for addressing global challenges.

    Science.gov (United States)

    Ricroch, Agnès E; Hénard-Damave, Marie-Cécile

    2016-08-01

    Most of the genetically modified (GM) plants currently commercialized encompass a handful of crop species (soybean, corn, cotton and canola) with agronomic characters (traits) directed against some biotic stresses (pest resistance, herbicide tolerance or both) and created by multinational companies. The same crops with agronomic traits already on the market today will continue to be commercialized, but there will be also a wider range of species with combined traits. The timeframe anticipated for market release of the next biotech plants will not only depend on science progress in research and development (R&D) in laboratories and fields, but also primarily on how demanding regulatory requirements are in countries where marketing approvals are pending. Regulatory constraints, including environmental and health impact assessments, have increased significantly in the past decades, delaying approvals and increasing their costs. This has sometimes discouraged public research entities and small and medium size plant breeding companies from using biotechnology and given preference to other technologies, not as stringently regulated. Nevertheless, R&D programs are flourishing in developing countries, boosted by the necessity to meet the global challenges that are food security of a booming world population while mitigating climate change impacts. Biotechnology is an instrument at the service of these imperatives and a wide variety of plants are currently tested for their high yield despite biotic and abiotic stresses. Many plants with higher water or nitrogen use efficiency, tolerant to cold, salinity or water submergence are being developed. Food security is not only a question of quantity but also of quality of agricultural and food products, to be available and accessible for the ones who need it the most. Many biotech plants (especially staple food) are therefore being developed with nutritional traits, such as biofortification in vitamins and metals. The main

  16. 7 Leadership Blind Spots: Adult Development, Emotional Intelligence, and Leadership Effectiveness Among Biotech R&D Leaders

    OpenAIRE

    Shiner, Michael

    2015-01-01

    In this multiple-case study of 6 mid-level leaders working in biotech R&D--an archetype of a complex, uncertain, turbulent, and, multidisciplinary 21st-Century workplace--I explore the importance and interaction of mental complexity (MC), an aspect of adult development, and emotional intelligence (EI) for leadership effectiveness (LE). MC concerns the sophistication of the mindsets we use to construct stories for ourselves about the meaning of things. EI refers to one’s ability to manage one’...

  17. Explaining ICT Infrastructure and E-Commerce Uses and Benefits in Industrial Clusters-Evidence from a Biotech Cluster

    DEFF Research Database (Denmark)

    Scupola, Ada; Steinfield, Charles

    2006-01-01

    in an industrial cluster might utilize and derive benefit from a public, broadband ICT infrastructure, particularly in support of e-commerce applications. A case study of a successful biotech cluster in Denamrk and Sweden-The Medicon Valley-provides a preliminary test of these expectations. Distinctions in uses...... and benefits based upon firm size are considered. A key finding is that small firms that would not otherwise be expected to gain from global e-commerce can rely on the cluster "brand" to enable trade with unknown and distant partners....

  18. Explaining ICT Infrastructure and E-Commerce Uses and Benefits in Industrial Clusters-Evidence from a Biotech Cluster

    DEFF Research Database (Denmark)

    Scupola, Ada; Steinfield, Charles

    2006-01-01

    industrial cluster might utilize and derive benefit from a public, broadband ICT infrastructure, particularly in support of e-commerce applications. A case study of a successful biotech cluster in Denamrk and Sweden-The Medicon Valley-provides a preliminary test of these expectations. Distinctions in uses...... and benefits based upon firm size are considered. A key finding is that small firms that would not otherwise be expected to gain from global e-commerce can rely on the cluster "brand" to enable trade with unknown and distant partners....

  19. Brief history of the Cambridge STEM aberration correction project and its progeny

    International Nuclear Information System (INIS)

    We provide a brief history of the project to correct the spherical aberration of the scanning transmission electron microscope (STEM) that started in Cambridge (UK) and continued in Kirkland (WA, USA), Yorktown Heights (NY, USA), and other places. We describe the project in the full context of other aberration correction research and related work, partly in response to the incomplete context presented in the paper “In quest of perfection in electron optics: A biographical sketch of Harald Rose on the occasion of his 80th birthday”, recently published in Ultramicroscopy. - Highlights: • We provide a brief history of the Cambridge project to correct the spherical aberration of the scanning transmission electron microscope (STEM). • We describe the project in the full context of other aberration correction work and related research. • We summarize our corrector development work that followed the Cambridge project, and which was the first to reach higher spatial resolution than any non-corrected electron microscope

  20. Brief history of the Cambridge STEM aberration correction project and its progeny

    Energy Technology Data Exchange (ETDEWEB)

    Brown, L. Michael [Cavendish Laboratory, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom); Batson, Philip E. [Institute for Advanced Materials, Devices and Nanotechnology, Rutgers University, Piscataway, NJ 08854 (United States); Department of Physics, Rutgers University, Piscataway, NJ 08854 (United States); Department of Materials Science, Rutgers University, Piscataway, NJ 08854 (United States); Dellby, Niklas [Nion Company, 11515 NE 118th Street, Kirkland, WA 98034 (United States); Krivanek, Ondrej L. [Nion Company, 11515 NE 118th Street, Kirkland, WA 98034 (United States); Department of Physics, Arizona State University, Tempe, AZ 85287 (United States)

    2015-10-15

    We provide a brief history of the project to correct the spherical aberration of the scanning transmission electron microscope (STEM) that started in Cambridge (UK) and continued in Kirkland (WA, USA), Yorktown Heights (NY, USA), and other places. We describe the project in the full context of other aberration correction research and related work, partly in response to the incomplete context presented in the paper “In quest of perfection in electron optics: A biographical sketch of Harald Rose on the occasion of his 80th birthday”, recently published in Ultramicroscopy. - Highlights: • We provide a brief history of the Cambridge project to correct the spherical aberration of the scanning transmission electron microscope (STEM). • We describe the project in the full context of other aberration correction work and related research. • We summarize our corrector development work that followed the Cambridge project, and which was the first to reach higher spatial resolution than any non-corrected electron microscope.

  1. Nutrition in medical education: reflections from an initiative at the University of Cambridge

    Directory of Open Access Journals (Sweden)

    Ball L

    2014-05-01

    Full Text Available Lauren Ball,1 Jennifer Crowley,2 Celia Laur,3 Minha Rajput-Ray,3 Stephen Gillam,4 Sumantra Ray3 1Nutrition and Dietetics, School of Allied Health Sciences, Centre for Health Practice Innovation, Griffith University, Queensland, Brisbane, Australia; 2Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; 3Need for Nutrition Education/Innovation Programme, Medical Research Council Human Nutrition Research, Cambridge, UK; 4Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK Abstract: Landmark reports have confirmed that it is within the core responsibilities of doctors to address nutrition in patient care. There are ongoing concerns that doctors receive insufficient nutrition education during medical training. This paper provides an overview of a medical nutrition education initiative at the University of Cambridge, School of Clinical Medicine, including 1 the approach to medical nutrition education, 2 evaluation of the medical nutrition education initiative, and 3 areas identified for future improvement. The initiative utilizes a vertical, spiral approach during the clinically focused years of the Cambridge undergraduate and graduate medical degrees. It is facilitated by the Nutrition Education Review Group, a group associated with the UK Need for Nutrition Education/Innovation Programme, and informed by the experiences of their previous nutrition education interventions. Three factors were identified as contributing to the success of the nutrition education initiative including the leadership and advocacy skills of the nutrition academic team, the variety of teaching modes, and the multidisciplinary approach to teaching. Opportunities for continuing improvement to the medical nutrition education initiative included a review of evaluation tools, inclusion of nutrition in assessment items, and further alignment of the Cambridge curriculum with the

  2. Analysis and Assessment of Cambridge English Skills Real Reading 2 within the Scope of Communicative Approach

    Institute of Scientific and Technical Information of China (English)

    张润霞

    2015-01-01

    this essay analyzes and assesses Cambridge English Skills Real Reading 2 from the perspective of communicative approach.The first part analyzes the theoretical basis of the textbook,including the organizational,pragmatic competence.The second part analyzes the syllabus contents.The last part analyzes the material and tasks of it.In summary,Cambridge English Skills Real Reading 2 is mainly communicative textbook from several aspects based on the detailed assessment and explanation.It can be helpful to the designing of reading textbooks.

  3. The Target of the Question: A Taxonomy of Textual Features for Cambridge University "O" Levels English

    Science.gov (United States)

    Benjamin, Shanti Isabelle

    2015-01-01

    This study investigates the typical textual features that are most frequently targeted in short-answer reading comprehension questions of the Cambridge University "O" Level English Paper 2. Test writers' awareness of how textual features impact on understanding of meanings in text decisions will determine to great extent their decisions…

  4. Final Report of Cambridge Conference on School Mathematics, January 1962 - August 1970.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    The Cambridge Conference on School Mathematics (CCSM) was an association of prominent mathematicians who had a concern for mathematics education at school level, from kindergarten through grade twelve. These mathematicians organized three main conferences in three areas of mathematics education, and have carried on activities related to the…

  5. The Singapore-Cambridge General Certificate of Education Advanced-Level General Paper Examination

    Science.gov (United States)

    Hassan, Nurul Huda; Shih, Chih-Min

    2013-01-01

    This article describes and reviews the Singapore-Cambridge General Certificate of Education Advanced Level General Paper (GP) examination. As a written test that is administered to preuniversity students, the GP examination is internationally recognised and accepted by universities and employers as proof of English competence. In this article, the…

  6. Up the Garden Path: A Chemical Trail through the Cambridge University Botanic Garden

    Science.gov (United States)

    Battle, Gary M.; Kyd, Gwenda O.; Groom, Colin R.; Allen, Frank H.; Day, Juliet; Upson, Timothy

    2012-01-01

    The living world is a rich source of chemicals with many medicines, dyes, flavorings, and foodstuffs having their origins in compounds produced by plants. We describe a chemical trail through the plant holdings of the Cambridge University Botanic Gardens. Visitors to the gardens are provided with a laminated trail guide with 22 stopping points…

  7. A Computerized Three-Dimensional Program Budget and Its Implementation at Cambridge School Department.

    Science.gov (United States)

    Wong, S. Godwin

    This report describes the APL (Accountable unit, Program, and line item) budget system, a computerized three-dimensional program budget system that has been implemented in the Cambridge (Massachusetts) School Department. Various chapters discuss the differences between traditional budgeting and program budgeting, present an overview of te APL…

  8. Technology Acquisition and Knowledge Networks : Knoweldge Economy Forum VI, Cambridge, United Kingdom

    OpenAIRE

    World Bank

    2007-01-01

    The paper is a report to cover the proceedings of the Knowledge Economy Forum VI held in Cambridge, UK in 2007. This report encapsulates the end product of the conference with regard to the current state of the European knowledge economy, especially in Eastern Europe.

  9. The present status of commercialized and developed biotech (GM) crops, results of evaluation of plum 'HoneySweet" for resistance to plum pox virus in the Czech Republic

    Science.gov (United States)

    Commercialization of biotech (GM) crops started in 1996. A significant increase of 9 million hectars was realized in 1996-2009. In the years 2010-2011, it was already 12 million hectars (8 percent of total crop area). 16.7 million farmers in 29 countries planted 160 million hectars of GM crops in...

  10. Mime, Music and Drama on the Eighteenth-Century Stage. The Ballet d'Action. Edward Nye, Cambridge-New York, Cambridge University Press, 2011

    Directory of Open Access Journals (Sweden)

    Stefania Onesti

    2012-11-01

    Full Text Available Mime, Music and Drama on the Eighteenth-Century Stage by Edward Nye (Cambridge University Press, 2011 has the merit of inspiring a strong reflection on ballet d'action, connected with cultural, literaturary and philosophic environment of Eighteenth century. The author, with brilliant insight and careful historical research, explores the most debated issues of the new genre, providing an unusual interpretation. The review traces the focal points and the structure of the book, developing further consideration of some of the most challenging aspects offered by the text.

  11. VizieR Online Data Catalog: Fourth Cambridge Survey (4C) (Pilkington+ 1965; Gower+ 1967)

    Science.gov (United States)

    Pilkington, J. D. H.; Scott, P. F.

    1996-04-01

    The Fourth Cambridge Radio Survey (4C) Catalogue contains all survey data from the papers of Pilkington and Scott (1965MmRAS..69..183P) and Gower, Scott and Wills (1967MmRAS..71...49G). These data result from a survey of radio sources between declinations -07 and +80 degrees using the large Cambridge interferometer at 178 MHz. The computerized catalog contains for each source the 4C number, 1950 position, measured flux density, accuracy class, galactic coordinates, and remarks. For some sources miscellaneous brief comments such as cross identifications to the 3C catalog or remarks on contamination from nearby sources are given at the ends of the data records. A flag (*) is included if there are additional remarks in the published catalog. (1 data file).

  12. The scientific impact of the Cambridge Structural Database: a citation-based study

    OpenAIRE

    Wong, R; Allen, F. H.; Willett, P.

    2010-01-01

    Four groups of the most highly cited scientific articles (46 in total), which either describe the Cambridge Structural Database (CSD) System or report scientific research applications of the CSD, have been selected for citation analysis. The analysis has been carried out to study the scientific importance of crystal structure information made available to the international research community via the CSD or via reviews and research articles that make use of the CSD as a primary information sou...

  13. PET/MRI in the infarcted mouse heart with the Cambridge split magnet

    International Nuclear Information System (INIS)

    Chronic heart failure, as a result of acute myocardial infarction, is a leading cause of death worldwide. Combining diagnostic imaging modalities may aid the direct assessment of experimental treatments targeting heart failure in vivo. Here we present preliminary data using the Cambridge combined PET/MRI imaging system in a mouse model of acute myocardial infarction. The split-magnet design can deliver uncompromised MRI and PET performance, for better assessment of disease and treatment in a preclinical environment

  14. The art and science of consultations in bovine medicine: Use of modified Calgary - Cambridge guides

    OpenAIRE

    Petrovski, Kiro R.; Michelle Mc Arthur

    2015-01-01

    This article describes few steps of the application of the modified Calgary-Cambridge Guides (CCG) to consultations in bovine medicine. A review of pertinent clinical communication skills literature in human medicine was integrated with the burgeoning research within veterinary medicine. In particular, there are more recent studies examining companion animal veterinarian’s communication skills and outcomes which can be extrapolated to practitioners. This was integrated into a teaching example...

  15. Item Response Theory Analyses of the Cambridge Face Memory Test (CFMT)

    OpenAIRE

    Cho, Sun-Joo; Wilmer, Jeremy; Herzmann, Grit; McGugin, Rankin; Fiset, Daniel; Van Gulick, Ana E.; Ryan, Katie; Gauthier, Isabel

    2015-01-01

    We evaluated the psychometric properties of the Cambridge face memory test (CFMT; Duchaine & Nakayama, 2006). First, we assessed the dimensionality of the test with a bi-factor exploratory factor analysis (EFA). This EFA analysis revealed a general factor and three specific factors clustered by targets of CFMT. However, the three specific factors appeared to be minor factors that can be ignored. Second, we fit a unidimensional item response model. This item response model showed that the CFMT...

  16. PET/MRI in the infarcted mouse heart with the Cambridge split magnet

    Energy Technology Data Exchange (ETDEWEB)

    Buonincontri, Guido, E-mail: gb396@cam.ac.uk [Wolfson Brain Imaging Centre, University of Cambridge, Box 65, Addenbrooke' s Hospital, Hills Road, Cambridge, CB2 0QQ (United Kingdom); Sawiak, Stephen J. [Wolfson Brain Imaging Centre, University of Cambridge, Box 65, Addenbrooke' s Hospital, Hills Road, Cambridge, CB2 0QQ (United Kingdom); Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge (United Kingdom); Methner, Carmen; Krieg, Thomas [Department of Medicine, University of Cambridge, Cambridge (United Kingdom); Hawkes, Robert C.; Adrian Carpenter, T. [Wolfson Brain Imaging Centre, University of Cambridge, Box 65, Addenbrooke' s Hospital, Hills Road, Cambridge, CB2 0QQ (United Kingdom)

    2013-02-21

    Chronic heart failure, as a result of acute myocardial infarction, is a leading cause of death worldwide. Combining diagnostic imaging modalities may aid the direct assessment of experimental treatments targeting heart failure in vivo. Here we present preliminary data using the Cambridge combined PET/MRI imaging system in a mouse model of acute myocardial infarction. The split-magnet design can deliver uncompromised MRI and PET performance, for better assessment of disease and treatment in a preclinical environment.

  17. Sir Joseph Barcroft, Cambridge placental and fetal research (1933-1966) and inter-generational Science.

    Science.gov (United States)

    Boyd, Robert; Boyd, C A Richard

    2010-01-01

    The nature of Cambridge (UK) placental and fetal research in the middle third of the twentieth century is reviewed on the basis of published literature and personal recollection. Joseph Barcroft is a central figure who came to fetal research late in an extremely productive career which is briefly sketched. Contemporaneous Cambridge academics in the field included J.D. Boyd (the authors father), J. Hammond, F.H.A. Marshall, R.A. McCance, J. Needham, A.S. Parkes and Elsie Widdowson. The then current Cambridge academic geography is explained and features of its scientific life such as funding, institutional structure and ethos, teaching and clinical duties, domestic and gender roles, and political context, including war and empire, are briefly considered. The testing of research findings against general principles and use of quantitative thinking are identified as important features. Intergenerational connections, often within individual families, are identified as a striking feature. The long-term impact of Cambridge work of this period; locally, in current trophoblast and feto-placental genetic research, in Oxford in probably influencing G.S. Dawes research leadership, and internationally, especially through D.H. Barron, and through him to the Denver School, is considered. That human placental and embryological specimens collected by J.D. Boyd have received a new lease of life as the "Boyd Collection", including use by Allen Enders is noted. Mechanisms for the maintenance of scientific quality and productivity during the period, mainly through the scientist himself relying on an internalised sense of "obligation", are contrasted with those current in the UK and more widely; formal peer-review at frequent intervals, with subsequent allocation of short-term funding. The strengths and weaknesses of each are considered. PMID:19876838

  18. Nutrition in medical education: reflections from an initiative at the University of Cambridge

    OpenAIRE

    Ball L; Crowley J; Laur C; Rajput-Ray M; Gillam S; Ray S

    2014-01-01

    Lauren Ball,1 Jennifer Crowley,2 Celia Laur,3 Minha Rajput-Ray,3 Stephen Gillam,4 Sumantra Ray3 1Nutrition and Dietetics, School of Allied Health Sciences, Centre for Health Practice Innovation, Griffith University, Queensland, Brisbane, Australia; 2Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; 3Need for Nutrition Education/Innovation Programme, Medical Research Council Human Nutrition Research, Cambridge, UK; 4Department of Public Health and Primary C...

  19. Cambridge Center for Behavioral Studies Turing Test Transcript for Terminal 5

    OpenAIRE

    Weintraub, Joseph

    1992-01-01

    Can machines think? Alan Turing's decades-old question still influences artificial intelligence because of the simple test he proposed in his article in Mind. In this article, "AI Magazine collects presentations about the first round of the classic Turing Test of machine intelligence, held November 8, 1991 at The Computer Museum, Boston. Robert Epstein, Director Emeritus, Cambridge Center for Behavioral Studies, and an adjunct professor of psychology, Boston University, University of Massachu...

  20. Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq)

    OpenAIRE

    Ravi Gupta; Richard P Allan; Ashwini Pundeer; Sourav Das; Mohan Dhyani; Deepak Goel

    2015-01-01

    Background: Restless legs syndrome also known as Willis-Ekbom′s Disease (RLS/WED) is a common illness. Cambridge-Hopkins diagnostic questionnaire for RLS (CHRLSq) is a good diagnostic tool and can be used in the epidemiological studies. However, its Hindi version is not available. Thus, this study was conducted to translate and validate it in the Hindi speaking population. Materials and Methods: After obtaining the permission from the author of the CHRLSq, it was translated into Hindi languag...

  1. Accumulation and Circulation of the Knowledge Needed for Biotech Business Promotion by Engineers of R&D Section in an IT Enterprise: The Case of Hitachi Software Engineering Co., Ltd

    Directory of Open Access Journals (Sweden)

    Hirofumi Ota

    2012-01-01

    Full Text Available Much research has been carried out on the accumulation and effective use of knowledge as a company-specific form of intellectual property. However, insufficient attention has been given to research focusing on the effects of micro-level knowledge absorption and its effective use. In this paper, we try to demonstrate what should be done in order to promote new biotech business from the perspective of each engineer’s knowledge, through a micro-level investigation focusing on the life science business section of one IT enterprise. Based on the results of a questionnaire survey of engineers, interviews of several engineers, and patent data analysis, we discuss the progress of the biotech business in an IT enterprise from the aspect of accumulation and circulation of knowledge in a core technology field, the IT business, and a technology field of new entry, the biotech business. This paper reports that the positive growth cycle of biotech business promotion in an IT enterprise, using Hitachi Software Engineering Co., Ltd. as a case, attained by incorporating the latest biotech knowledge from junior engineers and utilizing IT knowledge from middle engineers leads to the recruiting of qualified students.Keywords: accumulation and circulation of the knowledge, biotech business, open innovation, patent data analysis, questionnaire survey

  2. Adaptation of the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR into French-Canadian and English-Canadian

    Directory of Open Access Journals (Sweden)

    Donna Coffin

    2008-01-01

    Full Text Available BACKGROUND: The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR is the first disease-specific instrument for assessing patient-reported symptoms, functioning and quality of life (QoL in pulmonary arterial hypertension (PAH.

  3. Test pit excavation within currently occupied rural settlements: results of the University of Cambridge CORS project in 2011

    OpenAIRE

    Lewis, Carenza

    2012-01-01

    2011 saw the seventh year of test pit excavation within currently occupied rural settlements (CORS) in East Anglia carried out under the supervision of Access Cambridge Archaeology (ACA) directed by Dr Carenza Lewis at the University of Cambridge. As in previous years, this archaeological activity combines education and university outreach (particularly within the secondary school sector) with the archaeological investigation of currently occupied rural settlements (CO...

  4. Using the Cambridge structure database of organic and organometalic compounds in structure biology

    Czech Academy of Sciences Publication Activity Database

    Hašek, Jindřich

    2010-01-01

    Roč. 17, 1a (2010), b24-b26. ISSN 1211-5894. [Discussions in Structural Molecular Biology /8./. Nové Hrady, 18.03.2010-20.03.2010] R&D Projects: GA AV ČR IAA500500701; GA ČR GA305/07/1073 Institutional research plan: CEZ:AV0Z40500505 Keywords : organic chemistry * Cambridge Structure Database * molecular structure Subject RIV: CD - Macromolecular Chemistry http://xray.cz/ms/bul2010-1a/friday2.pdf

  5. Technology Solutions Case Study: Boiler Control Replacement for Hydronically Heated Multifamily Buildings, Cambridge, Massachusetts

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-11-01

    The ARIES Collaborative, a U.S. Department of Energy Building America research team, partnered with NeighborWorks America affiliate Homeowners' Rehab Inc. (HRI) of Cambridge, Massachusetts, to study improvements to the central hydronic heating system in one of the nonprofit's housing developments. The heating controls in the three-building, 42-unit Columbia Cambridge Alliance for Spanish Tenants housing development were upgraded. Fuel use in the development was excessive compared to similar properties. A poorly insulated thermal envelope contributed to high energy bills, but adding wall insulation was not cost-effective or practical. The more cost-effective option was improving heating system efficiency, which faced several obstacles, including inflexible boiler controls and failed thermostatic radiator valves. Boiler controls were replaced with systems that offer temperature setbacks and one that controls heat based on apartment temperature in addition to outdoor temperature. Utility bill analysis shows that post-retrofit weather-normalized heating energy use was reduced by 10%-31% (average of 19%). Indoor temperature cutoff reduced boiler runtime (and therefore heating fuel consumption) by 28% in the one building in which it was implemented. Nearly all savings were obtained during night which had a lower indoor temperature cut off (68°F) than day (73° F). This implies that the outdoor reset curve was appropriately adjusted for this building for daytime operation. Nighttime setback of heating system supply water temperature had no discernable impact on boiler runtime or gas bills.

  6. Building America Case Study: Boiler Control Replacement for Hydronically Heated Multifamily Buildings, Cambridge, Massachusetts (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2014-11-01

    The ARIES Collaborative, a U.S. Department of Energy Building America research team, partnered with NeighborWorks America affiliate Homeowners' Rehab Inc. (HRI) of Cambridge, Massachusetts, to study improvements to the central hydronic heating system in one of the nonprofit's housing developments. The heating controls in the three-building, 42-unit Columbia Cambridge Alliance for Spanish Tenants housing development were upgraded. Fuel use in the development was excessive compared to similar properties. A poorly insulated thermal envelope contributed to high energy bills, but adding wall insulation was not cost-effective or practical. The more cost-effective option was improving heating system efficiency. Efficient operation of the heating system faced several obstacles, including inflexible boiler controls and failed thermostatic radiator valves. Boiler controls were replaced with systems that offer temperature setbacks and one that controls heat based on apartment temperature in addition to outdoor temperature. Utility bill analysis shows that post-retrofit weather-normalized heating energy use was reduced by 10%-31% (average of 19%). Indoor temperature cutoff reduced boiler runtime (and therefore heating fuel consumption) by 28% in the one building in which it was implemented. Nearly all savings were obtained during night which had a lower indoor temperature cut off (68 degrees F) than day (73 degrees F). This implies that the outdoor reset curve was appropriately adjusted for this building for daytime operation. Nighttime setback of heating system supply water temperature had no discernable impact on boiler runtime or gas bills.

  7. Heliospheric tomography using interplanetary scintillation observations 1. Combined Nagoya and Cambridge data

    Science.gov (United States)

    Jackson, B. V.; Hick, P. L.; Kojima, M.; Yokobe, A.

    1998-06-01

    We have produced a computer assisted tomography program that optimizes a three-dimensional model to fit observational data. We have used this program with interplanetary scintillation data from Nagoya, Japan, and Cambridge, England. The program iterates to a least squares solution fit of observed data using solar rotation and solar wind motion to provide perspective views of each point in space accessible to the observations. We plot the optimized model as Carrington maps in velocity V and density Ne for the two data sets with resolutions of 10° in heliographic longitude and latitude. We map the model to 1 AU and compare this to in situ observations from the IMP spacecraft. From this comparison we find ΔNe~Ne0.3. We plot Carrington maps extrapolated to the solar surface to compare with Yohkoh Soft X ray Telescope (SXT), Sacramento Peak green line, and Mark III K-coronameter observations. High velocities modeled at the solar surface for individual rotations trace coronal holes (including polar ones) observed in SXT data. Regions of high density modeled from the Cambridge scintillation level data generally show a high correlation with regions of high solar activity observed as bright in Yohkoh SXT and green line observations. There is also a general correspondence of the regions of high density and the areas which are bright in K-coronameter observations.

  8. Fiftieth Anniversary of the Cambridge Structural Database and Thirty Years of Its Use in Croatia

    Directory of Open Access Journals (Sweden)

    Kojić-Prodić B.

    2015-07-01

    Full Text Available This article is dedicated to the memory of Dr. F. H. Allen and the 50th anniversary of the Cambridge Crystallographic Data Centre (CCDC; the world-renowned centre for deposition and control of crystallographic data including atomic coordinates that define the three-dimensional structures of organic molecules and metal complexes containing organic ligands. The mission exposed at the web site (http://www.ccdc.cam.ac.uk is clearly stated: “The Cambridge Crystallographic Data Centre (CCDC is dedicated to the advancement of chemistry and crystallography for the public benefit through providing high quality information, software and services.” The Cambridge Structural Database (CSD, one among the first established electronic databases, nowadays is one of the most significant crystallographic databases in the world. In the International Year of Crystallography 2014, the CSD announced in December over 750,000 deposited structures. The use of the extensive and rapidly growing database needs support of sophisticated and efficient software for checking, searching, analysing, and visualising structural data. The seminal role of the CSD in researches related to crystallography, chemistry, materials science, solid state physics and chemistry, (biotechnology, life sciences, and pharmacology is widely known. The important issues of the CCDC are the accuracy of deposited data and development of software for checking the data. Therefore, the Crystallographic Information File (CIF is introduced as the standard text file format for representing crystallographic information. Among the most important software for users is ConQuest, which enables searching all the CSD information fields, and the web implementation WebCSD software. Mercury is available for visualisation of crystal structures and crystal morphology including intra- and intermolecular interactions with graph-set notations of hydrogen bonds, and analysis of geometrical parameters. The CCDC gives even

  9. Evolution de l’industrie biotech et medtech suisse et influence de l’industrie pharmaceutique sur le système d’innovation

    OpenAIRE

    Klöpper, Christof; Haisch, Tina

    2010-01-01

    Cet article traite de l’influence d’un secteur ou d’une industrie dans l’économie nationale et de la manière dont il/elle peut influencer des secteurs et des technologies connexes. L’exemple choisi est constitué par l’industrie pharmaceutique suisse. L’article suggère que cette industrie a façonné le développement et la distribution spatiale des secteurs qui lui étaient liés, tels que les biotechnologies (biotech) et les technologies médicales (medtech). Il est supposé que cette influence dif...

  10. What affects the innovation performance of small and medium-sized enterprises (SMEs) in the biotechnology industry? An empirical study on Korean biotech SMEs.

    Science.gov (United States)

    Kang, Kyung-Nam; Lee, Yoon-Sik

    2008-10-01

    Research-intensive small and medium-sized enterprises (SMEs) play a crucial role in the advancement of the biotechnology industry. This paper explored the impacts of internal and contextual variables on innovative activity in Korea and compared the results of this analysis with previous studies of other countries. Our analysis of 149 Korean biotech SMEs showed that the ratio of R&D expenditure to sales, the ratio of R&D employees to total employees, CEO characteristics, governmental support and international networking are positively correlated with a firm's innovation performance. The results may help decision makers to better foster SMEs in the Korean biotechnology industry. PMID:18506395

  11. Bericht uber den 2. Internationalen Kongress fur Angewandte Linguistik. Cambridge 8.-12. IX. 1969. [Report on the Second International Congress for Applied Linguistics, Cambridge, Dec. 8-12, 1969.

    Science.gov (United States)

    Mohr, Peter

    This paper is a summary report on the Second International Congress of Applied Linguistics held in Cambridge, England in September 1969. Because of the large number of papers delivered, only a selection of the papers delivered in any one section of the Congress are considered, and the author attempts to identify current interests and trends in…

  12. Tartu Ülikooli teadur kaitses Cambridgeì Ülikoolis doktorikraadi / Krõõt Nõges

    Index Scriptorium Estoniae

    Nõges, Krõõt

    2006-01-01

    Tartu Ülikooli filosoofia osakonna teadur ja eetikakeskuse stipendiaat Eva Piirimäe kaitses Cambridgeì Ülikoolis doktorikraadi ideede ajaloo erialal doktoritööga "Thomas Abbt (1738-1766) and the Philosophical Genesis of German Nationalism"

  13. Two new spider species of the genus Chrysso O. P.-Cambridge, 1882 (Araneae, Theridiidae) in Hainan Island, China

    OpenAIRE

    Bao-Shi Zhang; Feng Zhang

    2012-01-01

    Abstract Two new spider species of the genus Chrysso O. P.-Cambridge, 1882 are reported from Hainan Island, China, Chrysso bifurca sp. n. (male, female) and Chrysso bicuspidata sp. n. (male, female). Chrysso bimaculata Yoshida, 1998is recorded from China for the first time.

  14. Jonathan Schlefer, The Assumptions Economists Make (Cambridge, Mass., and London: Belknap Press of Harvard University Press, 2012

    Directory of Open Access Journals (Sweden)

    Stuart Winchester

    2013-03-01

    Full Text Available A review of the book by Jonathan Schlefer: The Assumptions Economists Make (Cambridge, Mass., and London: Belknap Press of Harvard University Press, 2012, €26,10 / £21.95 / US$28.95, 356pp HBK (English, ISBN: 9780674052260.

  15. Public administration and R&D localisation by pharmaceutical and biotech companies: a theoretical framework and the Italian case-study.

    Science.gov (United States)

    Jommi, Claudio; Paruzzolo, Silvia

    2007-04-01

    This article has two objectives. It firstly provides a general framework for variables that influence R&D (Research and Development) localisation by pharmaceutical and biotech companies. The analysis of R&D localization includes both in-house R&D and contracted R&D. Following a systematic literature search, these variables were classified into four distinct categories: regulatory environment, institutional framework, national systems of innovation and local development and specialisation. The authors highlight that some of these factors directly depend on the action of public administrations (e.g., patent protection, price regulation, public investments in research, and incentives to private companies); others are indirectly influenced by public policies (e.g., GDP growth rate, infrastructures). This theoretical framework was used to analyse the Italian case-study. Pros and cons of the Italian context were investigated from the point of view of multinational pharmaceutical companies and the Italian Association of Biotech Companies. Interviews were chosen as the most appropriate data gathering technique given the exploratory nature of the study of the Italian context. The paper is divided into five parts. A brief introduction provides figures showing that Europe has been loosing positions compared with other Continents and the same has occurred in Italy compared with other EU countries. The second one illustrates the methodology. The third one is focused on variables affecting R&D localisation. In the fourth section the Italian case-study is discussed. Theoretical and empirical findings are summarised and discussed in the conclusions. PMID:16824641

  16. The present state of research and exploitation of biotech (GM) crops in horticulture: results of research on plum cv. 'HoneySweet' resistant to plum pox virus (Sharka) and the deregulation of this cultivar in the CR & Europe

    Science.gov (United States)

    Gentically modified (GM) crops were grown world-wide on 160 million ha in 2011. Only 114.57 ha of GM crops were grown in Europe, of that, 114.90 ha were Bt maize and 17 ha were potato for industrial starch production. Commercialization of Biotech crops started in 1995. Currently, developing count...

  17. Characteristic Conformation of Mosher’s Amide Elucidated Using the Cambridge Structural Database

    Directory of Open Access Journals (Sweden)

    Akio Ichikawa

    2015-07-01

    Full Text Available Conformations of the crystalline 3,3,3-trifluoro-2-methoxy-2-phenylpropanamide derivatives (MTPA amides deposited in the Cambridge Structural Database (CSD were examined statistically as Racid-enantiomers. The majority of dihedral angles (48/58, ca. 83% of the amide carbonyl groups and the trifluoromethyl groups ranged from –30° to 0° with an average angle θ1 of −13°. The other conformational properties were also clarified: (1 one of the fluorine atoms was antiperiplanar (ap to the amide carbonyl group, forming a staggered conformation; (2 the MTPA amides prepared from primary amines showed a Z form in amide moieties; (3 in the case of the MTPA amide prepared from a primary amine possessing secondary alkyl groups (i.e., Mosher-type MTPA amide, the dihedral angles between the methine groups and the carbonyl groups were syn and indicative of a moderate conformational flexibility; (4 the phenyl plane was inclined from the O–Cchiral bond of the methoxy moiety with an average dihedral angle θ2 of +21°; (5 the methyl group of the methoxy moiety was ap to the ipso-carbon atom of the phenyl group.

  18. Plasma-Surface Interaction Research At The Cambridge Laboratory Of Accelerator Studies Of Surfaces

    International Nuclear Information System (INIS)

    The material requirements for plasma-facing components in a nuclear fusion reactor are some of the strictest and most challenging facing us today. These materials are simultaneously exposed to extreme heat loads (20 MW/m2 steady-state, 1 GW/m2 in millisecond transients) and particle fluxes (>1024 m-2 s-1) while also undergoing high neutron irradiation (1018 neutrons/m2 s). At the Cambridge Laboratory of Accelerator Studies of Surfaces (CLASS), many of the most important issues in plasma-surface interaction research, such as plasma-driven material erosion and deposition, material transport and irradiation and hydrogenic retention are investigated with the use of a 1.7 MV tandem ion accelerator. Ion-Beam Analysis (IBA) is used to investigate and quantify changes in materials due to plasma exposure and ion irradiation is used as a proxy for neutron irradiation to investigate plasma-surface interactions for irradiated materials. This report will outline the capabilities and current research activities at CLASS.

  19. Minimal exposure technique in the Cambridge University 600kV high resolution electron microscope

    International Nuclear Information System (INIS)

    Radiation damage due to the incident electron beam imposes a fundamental limitation on the information obtainable by electron microscopy about organic materials; it is desirable therefore that exposure of the specimen to the electron beam should be restricted to the actual period during which the image is being recorded. A description is given of methods employed in the observation of the organic aromatic hydrocarbons quaterrylene, ovalene and coronene with the Cambridge University 600kV high resolution electron microscope (HREM). In particular, the condenser-objective mode of operation of this microscope lends itself to the use of an area-defining aperture below the second condenser lens conjugate with the specimen. Furthermore, operation at the higher accelerating voltage of this instrument could be anticipated to reduce the rate of damage, depending on the dominant beam-specimen interaction, whilst the increased width of the first broad band of the contrast transfer function of this microscope at the optimum defocus may overcome the reported resolution limitation of current 100kV microscopes for the observation of related materials. (author)

  20. Biotech as 'Biothreat'?

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte

    2008-01-01

    groups. In this, the paper tries to make up for the limited focus upon the role played by metaphor and discourse in shaping public attitudes of biotechnology. The paper has two parts; a theoretical part discussing the combination of conceptual metaphor studies and critical discourse analysis to provide a...... highly influenced by attitudes expressed by societal groups, based on the notions of risk, fear and danger....

  1. John Howard Marsden (1803–1891 First Disney Professor of Archaeology at the University of Cambridge 1851–1865

    Directory of Open Access Journals (Sweden)

    Michael Leach

    2007-05-01

    Full Text Available Although there were ten chairs of archaeology at universities in Germany, and one in France, by the mid-nineteenth century, in Great Britain it was the amateur societies and museums (the British Museum in particular that encouraged the study of this subject. In 1851 John Disney established the first university chair in Great Britain at Cambridge University. His proposal was initially received with considerable caution by the governing body of the university, and was only accepted by the narrowest margin of eight votes to seven. His agreement with the University of Cambridge stipulated that six lectures a year should be given on the subject of ‘Classical, Medieval, and other Antiquities, the Fine Arts and all matters and things connected therewith’ (Clark 1904, 222–225. However university archaeology was slow to establish its academic credibility nationally, and it was more than thirty years before Oxford University established its chair of classical archaeology. The Cambridge Board of Anthropological Studies, which included instruction in prehistoric archaeology, was not created until 1915, and as late as 1945 there were still only a few university lecturers in archaeology in Great Britain. It was not until 1946 that Oxford University appointed a Professor of Prehistoric Archaeology (Wilson 2002, 153; Daniel 1976, 6–12; Smith 2004, 4–5, 53–54.

  2. A robust method of measuring other-race and other-ethnicity effects: the Cambridge Face Memory Test format.

    Science.gov (United States)

    McKone, Elinor; Stokes, Sacha; Liu, Jia; Cohan, Sarah; Fiorentini, Chiara; Pidcock, Madeleine; Yovel, Galit; Broughton, Mary; Pelleg, Michel

    2012-01-01

    Other-race and other-ethnicity effects on face memory have remained a topic of consistent research interest over several decades, across fields including face perception, social psychology, and forensic psychology (eyewitness testimony). Here we demonstrate that the Cambridge Face Memory Test format provides a robust method for measuring these effects. Testing the Cambridge Face Memory Test original version (CFMT-original; European-ancestry faces from Boston USA) and a new Cambridge Face Memory Test Chinese (CFMT-Chinese), with European and Asian observers, we report a race-of-face by race-of-observer interaction that was highly significant despite modest sample size and despite observers who had quite high exposure to the other race. We attribute this to high statistical power arising from the very high internal reliability of the tasks. This power also allows us to demonstrate a much smaller within-race other ethnicity effect, based on differences in European physiognomy between Boston faces/observers and Australian faces/observers (using the CFMT-Australian). PMID:23118912

  3. The art and science of consultations in bovine medicine: Use of modified Calgary - Cambridge guides

    Directory of Open Access Journals (Sweden)

    Kiro R. Petrovski

    2015-10-01

    Full Text Available This article describes few steps of the application of the modified Calgary-Cambridge Guides (CCG to consultations in bovine medicine. A review of pertinent clinical communication skills literature in human medicine was integrated with the burgeoning research within veterinary medicine. In particular, there are more recent studies examining companion animal veterinarian’s communication skills and outcomes which can be extrapolated to practitioners. This was integrated into a teaching example of a reproductive case consultation. The first article deals with the 1 Preparation, 2 Initiating the Session and 3 Gathering Information sections. The aim of the modified CCG is to provide a set of skills to facilitate a relationship-centred approach to consultations in bovine medicine, both at the individual animal and population level. They were initially developed for human medicine and expanded recently for use in veterinary medicine. The CCG enable the practitioner to facilitate interacting with that particular client at the time of the consultation. It is likely that the majority of practitioners do use many of the skills recommended by the modified CCG. These skills are often gained through experience. However, they may not use the skills intentionally and with purpose for a specific communication goal or outcome. Practitioners can improve their communication skills using the set of skills as recommended by the modified CCG. They allow the practitioner to gain insight into the client’s understanding of the problem, including underlying aetiology, epidemiology and pathophysiology. The guides also provide opportunity to understand client’s expectations regarding the outcome, motivation and willingness to change and adherence.

  4. Evaluation of a brief anti-stigma campaign in Cambridge: do short-term campaigns work?

    Directory of Open Access Journals (Sweden)

    Henderson Claire

    2010-06-01

    Full Text Available Abstract Background In view of the high costs of mass-media campaigns, it is important to understand whether it is possible for a media campaign to have significant population effects over a short period of time. This paper explores this question specifically in reference to stigma and discrimination against people with mental health problems using the Time to Change Cambridge anti-stigma campaign as an example. Methods 410 face-to-face interviews were performed pre, during and post campaign activity to assess campaign awareness and mental health-related knowledge, attitudes and behaviours. Results Although campaign awareness was not sustained following campaign activity, significant and sustained shifts occurred for mental health-related knowledge items. Specifically, there was a 24% (p If a friend had a mental health problem, I know what advice to give them to get professional help, following the campaign. Additionally, for the statement: Medication can be an effective treatment for people with mental health problems, there was a 10% rise (p = 0.05 in the proportion of interviewees responding 'agree' or 'strongly agree' following the campaign. These changes, however, were not evident for attitudinal or behaviour related questions. Conclusions Although these results only reflect the impact of one small scale campaign, these preliminary findings suggest several considerations for mass-media campaign development and evaluation strategies such as: (1 Aiming to influence outcomes pertaining to knowledge in the short term; (2 Planning realistic and targeted outcomes over the short, medium and long term during sustained campaigns; and (3 Monitoring indirect campaign effects such as social discourse or other social networking/contact in the evaluation.

  5. Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq

    Directory of Open Access Journals (Sweden)

    Ravi Gupta

    2015-01-01

    Full Text Available Background: Restless legs syndrome also known as Willis-Ekbom′s Disease (RLS/WED is a common illness. Cambridge-Hopkins diagnostic questionnaire for RLS (CHRLSq is a good diagnostic tool and can be used in the epidemiological studies. However, its Hindi version is not available. Thus, this study was conducted to translate and validate it in the Hindi speaking population. Materials and Methods: After obtaining the permission from the author of the CHRLSq, it was translated into Hindi language by two independent translators. After a series of forward and back translations, the finalized Hindi version was administered to two groups by one of the authors, who were blinded to the clinical diagnosis. First group consisted of RLS/WED patients, where diagnosis was made upon face to face interview and the other group - the control group included subjects with somatic symptoms disorders or exertional myalgia or chronic insomnia. Each group had 30 subjects. Diagnosis made on CHRLSq was compared with the clinical diagnosis. Statistical Analysis: Analysis was done using Statistical Package for Social Sciences (SPSS v 21.0. Descriptive statistics was calculated. Proportions were compared using chi-square test; whereas, categorical variables were compared using independent sample t-test. Sensitivity, specificity, and positive predictive value of the translated version of questionnaire were calculated. Results: Average age was comparable between the cases and control group (RLS/WED = 39.1 ± 10.1 years vs 36.2 ± 11.4 years in controls; P = 0.29. Women outnumbered men in the RLS/WED group (87% in RLS/WED group vs 57% among controls; χ2 = 6.64; P = 0.01. Both the sensitivity and specificity of the translated version was 83.3%. It had the positive predictive value of 86.6%. Conclusion: Hindi version of CHRLSq has positive predictive value of 87% and it can be used to diagnose RLS in Hindi speaking population.

  6. Judicial activism, the Biotech Directive and its institutional implications – Is the Court acting as a legislator or a court when defining the ‘human embryo’?

    DEFF Research Database (Denmark)

    Faeh, Andrea Beata

    2015-01-01

    The Court of Justice of the European Union (Court) delivered a preliminary ruling in 2011 in the case of Oliver Brüstle v Greenpeace on the interpretation of Article 6(2) of the Biotech Directive and thereby established an autonomous concept of the term ‘human embryo’. The Brüstle decision raises a...... autonomous interpretation of ‘human embryo’ and the flexibility allowed to the national courts needed further clarification. This clarification was recently given by the Court’s Grand Chamber in International Stem Cell Corporation v Comptroller General Patents where the Court concluded that a non......-fertilised human ovum, not capable of developing into a human being, is not a ‘human embryo’. Hence, ‘where a non-fertilised human ovum does not fulfil that condition [inherent capacity of developing into a human being], the mere fact that that organism commences a process of development is not sufficient for it...

  7. Cambridge-Cranfield High Performance Computing Facility (HPCF) purchases ten Sun Fire(TM) 15K servers to dramatically increase power of eScience research

    CERN Multimedia

    2002-01-01

    "The Cambridge-Cranfield High Performance Computing Facility (HPCF), a collaborative environment for data and numerical intensive computing privately run by the University of Cambridge and Cranfield University, has purchased 10 Sun Fire(TM) 15K servers from Sun Microsystems, Inc.. The total investment, which includes more than $40 million in Sun technology, will dramatically increase the computing power, reliability, availability and scalability of the HPCF" (1 page).

  8. Correlates of time spent walking and cycling to and from work: baseline results from the commuting and health in Cambridge study

    OpenAIRE

    Panter Jenna; Griffin Simon; Jones Andrew; Mackett Roger; Ogilvie David

    2011-01-01

    Abstract Purpose Environmental perceptions and psychological measures appear to be associated with walking and cycling behaviour; however, their influence is still unclear. We assessed these associations using baseline data from a quasi-experimental cohort study of the effects of major transport infrastructural developments in Cambridge, UK. Methods Postal surveys were sent to adults who travel to work in Cambridge (n = 1582). Questions asked about travel modes and time spent travelling to an...

  9. 50-Godišnjica Cambridge Structural Database i 30-godišnjica uporabe u Hrvatskoj

    OpenAIRE

    Kojić-Prodić, B.; Molčanov, K.

    2015-01-01

    Prikaz je posvećen uspomeni na dr. F. H. Allena i obilježavanju 50-godišnjice The Cambridge Crystallographic Data Centre (CCDC), svjetski poznatog centra, koji pohranjuje i provjerava kristalografske podatke, uključujući koordinate atoma koje određuju trodimenzijsku strukturu organskih molekula i metalnih kompleksa s organskim ligandima. Misija institucije istaknuta na njezinim web-stranicama je jasna: “Centar za kristalografske podatke u Cambridgeu (CCDC) potpomaže napredak kemije i kristalo...

  10. Nano Si preparation by constant cell voltage electrolysis of FFC-Cambridge Process in molten CaCl2

    Institute of Scientific and Technical Information of China (English)

    Ji; Zhao; Shengmei; Lu; Linyan; Hu; Can; Li

    2013-01-01

    Using FFC-Cambridge Process to prepare Si from SiO2 is a promising method to prepare nanostructured and highly pure silicon for solar cells.However,the method still has many problems unsolved and the controlling effect of the cell voltage on silicon product is not clear.Here we report in this article that nano cluster-like silicon product with purity of 99.95%has been prepared by complete conversion of raw material SiO2,quartz glass plate,using constant cell voltage electrolysis FFC-Cambridge Process.By analysis of XRD,EDS,TEM,HRTEM and ICP-AES as well as the discussion from the thermodynamics calculation,the morphology and components of the product based on the change of cell voltage are clarified.It is clear that pure silicon could be prepared at the cell voltage of 1.7 2.1 V in this reaction system.The silicon material have cluster-like structure which are made of silicon nanoparticles in 20 100 nm size.Interestingly,the cluster-like nano structure of the silicon can be tuned by the used cell voltage.The purity,yield and the energy cost of silicon product prepared at the optimized cell voltage are discussed.The purity of the silicon product could be further improved,hence this method is promising for the preparation of solar grade silicon in future.

  11. Diagnosis of mild chronic pancreatitis (Cambridge classification): Comparative study using secretin injection-magnetic resonance cholangiopancreatography and endoscopic retrograde pancreatography

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    AIM: To investigate the usefulness of secretin injection MRCP for the diagnosis of mild chronic pancreatitis. METHODS: Sixteen patients having mild chronic pancreatitis according to the Cambridge classification and 12 control subjects with no abnormal findings on the pancreatogram were examined for the diagnostic accuracy of secretin injection-MRCP regarding abnormal branch pancreatic ducts associated with mild chronic pancreatitis (Cambridge Classification), using endoscopic retrograde cholangiopancreatography (ERCP) for comparison. RESULTS: The sensitivity and specificity for abnormal branch pancreatic ducts determined by two reviewers were respectively 55%-63% and 75%-83% in the head, 57%-64% and 82%-83% in the body, and 44%-44%and 72%-76% in the tail of the pancreas. The sensitivity and specificity for mild chronic pancreatitis were 56%-63% and 92%-92%, respectively. Interobserver abnormal branch pancreatic duct and of mild chronic pancreatitis was good to excellent. CONCLUSION: Secretin injection-MRCP might be useful for the diagnosis of mild chronic pancreatitis.

  12. 近年来我国生物技术药物研究进展和趋势%The Research Progress and Trend of Biotech Drugs in Recent Years in China

    Institute of Scientific and Technical Information of China (English)

    王友同; 吴文俊; 李谦; 高美风

    2013-01-01

    Biological technology is the topic height at the development of economy and technology in the 21st century all over the world . The authors based on the world biotech- drugs total development trend, summarized the biotech drugs research achievements in recent five years in China. The content includes: cytokine, protein and peptide drugs, fusion protein, cell-penetrating peptides, enzymes,gene therapy,stem cells,monoclonal antibodies,therapeutic vaccine,polysaccharide drugs,etc. It is found in the survey that the development of biotech drugs has a bright future in treating complicated diseases, protecting the human health, improving the life quality, and developing the biotech drugs industry, thank to the emerging of many creative biotech drug researches within our country. This paper provides the reference for establishing the relevant research plan, deciding the research project, setting development goals for enterprise research,and choosing professional development direction,and to biological pharmaceutical researchers.%生物技术是21世纪世界各国竞相发展的经济、技术的制高点,作者站在世界生物技术药物发展总趋势的高度上,具体而微地调查和总结了我国近5年来生物技术药物研究所取得的成果,内容包括:细胞因子、其它蛋白质和多肽药物、融合蛋白、穿膜肽、酶、基因治疗、干细胞、单克隆抗体、治疗性疫苗及多糖药物等.调查发现,在攻克人类顽疾、保障人民身体健康、提高生活质量和发展我国生物技术药物产业方面,由于国内成批有创见的研究成果持续涌现,发展前景一片光明.该文可为有关部门科研规划、确定研究项目、企业锁定发展目标及生物制药人员选择专业发展方向提供参考.

  13. Identification of the factors that result in obviousness rulings for biotech patents: an updated analysis of the US Federal Circuit decisions after KSR.

    Science.gov (United States)

    Lin, Fangyu; Wang, Shyh-Jen

    2013-11-01

    To demonstrate the influence of the US Supreme Court's KSR case, our analysis has shown that the ratio of obvious ruling increased from 0.42 to 0.62 after this case, whereas the ratio of non-obvious ruling decreased from 0.47 to 0.28. Therefore, without the rigid application of a "teaching, suggestion or motivation" test, the trends of obvious and non-obvious CAFC rulings significantly increased and decreased, respectively.   Based on this analysis, biotech inventors should contemplate the factors that have resulted in ruling of obviousness, which include claims that are too broad, the lack of secondary considerations, the reasonable expectation of success, and the reason or motivation to create a structure based on structural similarity. The presence of these factors most likely would result in the rejection of the claim during patent prosecution or the invalidation of the claim in patent litigation. Two immunotherapy and vaccine cases have applied these factors to overcome the obvious rejections. PMID:23899509

  14. Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 3. The Cambridge Structural Database System: Information Content and Access Software in Educational Applications

    Science.gov (United States)

    Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

    2011-01-01

    Parts 1 and 2 of this series described the educational value of experimental three-dimensional (3D) chemical structures determined by X-ray crystallography and retrieved from the crystallographic databases. In part 1, we described the information content of the Cambridge Structural Database (CSD) and discussed a representative teaching subset of…

  15. Trajectories of Offending and Their Relation to Life Failure in Late Middle Age: Findings from the Cambridge Study in Delinquent Development

    Science.gov (United States)

    Piquero, Alex R.; Farrington, David P.; Nagin, Daniel S.; Moffitt, Terrie E.

    2010-01-01

    Researchers have hypothesized that over the life course, criminal offending varies with problems in other domains, including life failure and physical and mental health. To examine this issue, the authors use data from the Cambridge Study in Delinquent Development, a prospective longitudinal survey of 411 South London males first studied at age 8…

  16. Boone Schirmer and the Early Days of the Philippines Information Bulletin, Friends of the Filipino People, and the Philippines Program at Goddard-Cambridge

    OpenAIRE

    Gaerlan, Barbara S.

    2006-01-01

    Daniel Boone Schirmer had a lasting impact on the movement in the United States to oppose martial law in the Philippines from 1972 until his death in 2006. He was active in several AMLM institutions such as the Philippines Information Bulletin, Friends of the Filipino People, and the Philippines program of the Goddard-Cambridge Graduate Program in Social Change.

  17. Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study

    NARCIS (Netherlands)

    F.H. Allen; A.J. Cruz-Cabeza; P.A. Wood; D.A. Bardwell

    2013-01-01

    As part of a programme of work to extend central-group coverage in the Cambridge Crystallographic Data Centre's (CCDC) IsoStar knowledge base of intermolecular interactions, we have studied the hydrogen-bonding abilities of squaric acid (H(2)SQ) and its mono-and dianions (HSQ(-) and SQ(2-)) using th

  18. Applicability of the Calgary-Cambridge Guide to Dog and Cat Owners for Teaching Veterinary Clinical Communications.

    Science.gov (United States)

    Englar, Ryane E; Williams, Melanie; Weingand, Kurt

    2016-01-01

    Effective communication in health care benefits patients. Medical and veterinary schools not only have a responsibility to teach communication skills, the American Veterinary Medical Association (AVMA) Council on Education (COE) requires that communication be taught in all accredited colleges of veterinary medicine. However, the best strategy for designing a communications curriculum is unclear. The Calgary-Cambridge Guide (CCG) is one of many models developed in human medicine as an evidence-based approach to structuring the clinical consultation through 71 communication skills. The model has been revised by Radford et al. (2006) for use in veterinary curricula; however, the best approach for veterinary educators to teach communication remains to be determined. This qualitative study investigated if one adaptation of the CCG currently taught at Midwestern University College of Veterinary Medicine (MWU CVM) fulfills client expectations of what constitutes clinically effective communication. Two focus groups (cat owners and dog owners) were conducted with a total of 13 participants to identify common themes in veterinary communication. Participants compared communication skills they valued to those taught by MWU CVM. The results indicated that while the CCG skills that MWU CVM adopted are applicable to cat and dog owners, they are not comprehensive. Participants expressed the need to expand the skillset to include compassionate transparency and unconditional positive regard. Participants also expressed different communication needs that were attributed to the species of companion animal owned. PMID:27075274

  19. The use of remote temperature measurement for a bio-remediation pilot project in Cambridge Bay, Nunavut

    Energy Technology Data Exchange (ETDEWEB)

    McCullogh, R.W. [Jacques Whitford Environment Ltd., Dartmouth, NS (Canada); Burkill, R. [Transport Canada, Ottawa, ON (Canada)

    2001-07-01

    Several remote sites in Arctic Canada are contaminated with diesel fuel from leaky storage tanks. Soil remediation in these permafrost areas is expensive and time consuming. A study was conducted at the Cambridge Bay Transmitter site to develop a soil treatment method that can be used to clean-up small volumes of contaminated soils at sites across the Arctic with similar climates and geology. Bioremediation is generally an effective way to treat contaminated soils, but ambient temperature is the main limiting factor associated with bioremediation of hydrocarbon impacted soil in Arctic environments. As temperatures approach 5 degrees C, the rates of microbial activity are very much reduced. This study examined the temperature of the soil to determine the performance of bioremediation processes and to optimize heat preservation. A series of thermocouples were installed to monitor soil and ambient temperatures. The statistical data showing the temperature conditions at the site can be applied to other contaminated sites. This paper described the data logger installation, the available data and how it can be used to design and monitor remediation projects in the Arctic. 5 refs., 9 figs.

  20. Definition and Research of the Rejection Rate of Cambridge Filter%剑桥滤片截留率的定义与研究

    Institute of Scientific and Technical Information of China (English)

    马营

    2016-01-01

    The sealing performance of the seal gasket and labyrinth ring of cigarette catching device of smoking machine is not easy to find. Through studying the definition and calculation method of the rejection rate of Cambridge filter, the seal of cigarette filter is judged by the interception rate of Cambridge filter to ensure the accurate detection data of the mainstream smoke.%吸烟机卷烟捕集器密封垫片和迷宫环密封性能好坏不易直观发现,通过研究剑桥滤片截留率的定义与计算方法,依据剑桥滤片截留率数据判断卷烟捕集器密封性,保证主流烟气的检测数据准确。

  1. Development and validation of a preference based measure derived from the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for use in cost utility analyses

    OpenAIRE

    Meads David M; Ratcliffe Julie; McKenna Stephen P; Brazier John E

    2008-01-01

    Abstract Background Pulmonary Hypertension is a severe and incurable disease with poor prognosis. A suite of new disease-specific measures – the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) – was recently developed for use in this condition. The purpose of this study was to develop and validate a preference based measure from the CAMPHOR that could be used in cost-utility analyses. Methods Items were selected that covered major issues covered by the CAMPHOR QoL scale (activities,...

  2. The ADDITION-Cambridge trial protocol: a cluster – randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients

    OpenAIRE

    Kinmonth Ann; Prevost A Toby; Barling Roslyn S; Williams Kate M; Simmons Rebecca K; Echouffo-Tcheugui Justin B; Wareham Nicholas J; Griffin Simon J

    2009-01-01

    Abstract Background The increasing prevalence of type 2 diabetes poses a major public health challenge. Population-based screening and early treatment for type 2 diabetes could reduce this growing burden. However, the benefits of such a strategy remain uncertain. Methods and design The ADDITION-Cambridge study aims to evaluate the effectiveness and cost-effectiveness of (i) a stepwise screening strategy for type 2 diabetes; and (ii) intensive multifactorial treatment for people with screen-de...

  3. Comparison of the Diagnostic Accuracy of Neuropsychological Tests in Differentiating Alzheimer's Disease from Mild Cognitive Impairment: Can the Montreal Cognitive Assessment Be Better than the Cambridge Cognitive Examination?

    OpenAIRE

    Martinelli, José Eduardo; Cecato, Juliana Francisca; Bartholomeu, Daniel; Montiel, José Maria

    2014-01-01

    Objective Considering the lack of studies on measures that increase the diagnostic distinction between Alzheimer's disease (AD) and mild cognitive impairment (MCI) and on the role of the Cambridge Cognitive Examination (CAMCOG) in this, our study aims to compare the utility of the CAMCOG, Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) in helping to differentiate AD from MCI in elderly people with >4 years of schooling. Method A total of 136 elderly subjects – 39...

  4. An analysis of infection control of varicella-zoster virus infections in Addenbrooke's Hospital Cambridge over a 5-year period, 1987-92.

    OpenAIRE

    Wreghitt, T G; Whipp, J.; Redpath, C.; Hollingworth, W.

    1996-01-01

    This prospective study analyses infections with varicella-zoster virus (VZV) in Addenbrooke's Hospital, Cambridge during 1987-92 and examines the spread of infection. In total, 93 patients and staff experienced VZV infection. Twenty-one patients had varicella and 49 experienced zoster. None of 101 patients and 1 of 625 staff members in contact with varicella cases acquired infection. By contrast, 2 of 227 patients, and 5 of 1039 staff in contact with zoster cases acquired varicella. One out o...

  5. Cambridge IGCSE physics

    CERN Document Server

    Kennett, Heather; Konrad, Nina

    2014-01-01

    The bestselling title, developed by International experts - now updated to offer comprehensive coverage of the core and extended topics in the latest syllabus. - Includes a student's CD-ROM featuring interactive tests and practice for all examination papers- Covers the core and supplement sections of the updated syllabus- Supported by the most comprehensive range of additional material, including Teacher Resources, Laboratory Books, Practice Books and Revision Guides- Written by renowned, expert authors with vast experience of teaching and examining international qualifications We are working

  6. Scientific Basis for Biotech Crops

    Science.gov (United States)

    Efforts to change the genetic makeup of plants have been ongoing since the beginning of agriculture, thousands of years ago. Early plant improvements relied on simply cross-breeding cultivars with desired traits. Advancements in mutation breeding through chemicals and radiation ...

  7. Space Biotech: Hindsight, Insight, Foresight

    Science.gov (United States)

    Harper, Lynn

    2015-01-01

    Over the past forty years, microgravity has inspired and enabled applications in a wide range of sectors including medicine, materials, computers, communications, and national defense. Trends show that demand for high-tech solutions is increasing in these sectors, solutions that require higher resolution, greater precision, novel materials, innovative processes, and more sophisticated tools. These are areas where microgravity can offer unique capabilities for innovation. The Emerging Space Office (ESO) has engaged in multiple studies over the past year that have found that microgravity RD is one of the most promising technology areas for contributing to economic growth and to NASAs mission. The focus of these studies was on terrestrial markets rather than NASA applications, applied research rather than basic research, and commercial rather than academic investigators. There have been more success stories than are generally appreciated and there are significant areas of promising future potential. Many of the problems that have limited commercial microgravity development in the past are being solved. Microgravity research and development (RD) requires iteration and learning, as rapidly as possible. New technologies enable high throughput and rapid data collection in increasingly small payloads. The International Space Station is in orbit and provides a laboratory that is available 247 at least until 2024. Frequent flights by commercial space providers to and from the ISS now enable the fast learning cycles needed by high-tech industries. Launch costs are decreasing and the ability to return payloads to Earth is increasing. New commercial space laboratories, such as those being developed by SpaceX and Bigelow Aerospace, are in the final stages of development and testing. This ecosystem for microgravity RD has never been available before. These are game-changer conditions for attracting high-tech industries to space for terrestrial, as well as NASA, applications. However, few know that these capabilities are available or how to use them. In aggregate, the potential value for new applications from microgravity RD over the next ten years could add billions of dollars per year in terrestrial applications to the future economy, create new jobs, and generate a wide range of public benefits in medical advances, while broadening the customer base for the emerging space industry.

  8. Potential reductions of street solids and phosphorus in urban watersheds from street cleaning, Cambridge, Massachusetts, 2009-11

    Science.gov (United States)

    Sorenson, Jason R.

    2013-01-01

    Material accumulating and washing off urban street surfaces and ultimately into stormwater drainage systems represents a substantial nonpoint source of solids, phosphorus, and other constituent loading to waterways in urban areas. Cost and lack of usable space limit the type and number of structural stormwater source controls available to municipalities and other public managers. Non-structural source controls such as street cleaning are commonly used by cities and towns for construction, maintenance and aesthetics, and may reduce contaminant loading to waterways. Effectiveness of street cleaning is highly variable and potential improvements to water quality are not fully understood. In 2009, the U.S. Geological Survey, in cooperation with the Massachusetts Department of Environmental Protection, the U.S. Environmental Protection Agency, and the city of Cambridge, Massachusetts, and initiated a study to better understand the physical and chemical nature of the organic and inorganic solid material on street surfaces, evaluate the performance of a street cleaner at removing street solids, and make use of the Source Loading and Management Model (SLAMM) to estimate potential reductions in solid and phosphorus loading to the lower Charles River from various street-cleaning technologies and frequencies. Average yield of material on streets collected between May and December 2010, was determined to be about 740 pounds per curb-mile on streets in multifamily land use and about 522 pounds per curb-mile on commercial land-use streets. At the end-of-winter in March 2011, about 2,609 and 4,788 pounds per curb-mile on average were collected from streets in multifamily and commercial land-use types, respectively. About 86 percent of the total street-solid yield from multifamily and commercial land-use streets was greater than or equal to 0.125 millimeters in diameter (or very fine sand). Observations of street-solid distribution across the entire street width indicated that as

  9. Hydrogen-bond landscapes, geometry and energetics of squaric acid and its mono- and dianions: a Cambridge Structural Database, IsoStar and computational study.

    Science.gov (United States)

    Allen, Frank H; Cruz-Cabeza, Aurora J; Wood, Peter A; Bardwell, David A

    2013-10-01

    As part of a programme of work to extend central-group coverage in the Cambridge Crystallographic Data Centre's (CCDC) IsoStar knowledge base of intermolecular interactions, we have studied the hydrogen-bonding abilities of squaric acid (H2SQ) and its mono- and dianions (HSQ(-) and SQ(2-)) using the Cambridge Structural Database (CSD) along with dispersion-corrected density functional theory (DFT-D) calculations for a range of hydrogen-bonded dimers. The -OH and -C=O groups of H2SQ, HSQ(-) and SQ(2-) are potent donors and acceptors, as indicated by their hydrogen-bond geometries in available crystal structures in the CSD, and by the attractive energies calculated for their dimers with acetone and methanol, which were used as model acceptors and donors. The two anions have sufficient examples in the CSD for their addition as new central groups in IsoStar. It is also shown that charge- and resonance-assisted hydrogen bonds involving H2SQ and HSQ(-) are similar in strength to those made by carboxylate COO(-) acceptors, while hydrogen bonds made by the dianion SQ(2-) are somewhat stronger. The study reinforces the value of squaric acid and its anions as cocrystal formers and their actual and potential importance as isosteric replacements for carboxylic acid and carboxylate functions. PMID:24056361

  10. The ADDITION-Cambridge trial protocol: a cluster – randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients

    Directory of Open Access Journals (Sweden)

    Kinmonth Ann

    2009-05-01

    Full Text Available Abstract Background The increasing prevalence of type 2 diabetes poses a major public health challenge. Population-based screening and early treatment for type 2 diabetes could reduce this growing burden. However, the benefits of such a strategy remain uncertain. Methods and design The ADDITION-Cambridge study aims to evaluate the effectiveness and cost-effectiveness of (i a stepwise screening strategy for type 2 diabetes; and (ii intensive multifactorial treatment for people with screen-detected diabetes in primary care. 63 practices in the East Anglia region participated. Three undertook the pilot study, 33 were allocated to three groups: no screening (control, screening followed by intensive treatment (IT and screening plus routine care (RC in an unbalanced (1:3:3 randomisation. The remaining 27 practices were randomly allocated to IT and RC. A risk score incorporating routine practice data was used to identify people aged 40–69 years at high-risk of undiagnosed diabetes. In the screening practices, high-risk individuals were invited to take part in a stepwise screening programme. In the IT group, diabetes treatment is optimised through guidelines, target-led multifactorial treatment, audit, feedback, and academic detailing for practice teams, alongside provision of educational materials for newly diagnosed participants. Primary endpoints are modelled cardiovascular risk at one year, and cardiovascular mortality and morbidity at five years after diagnosis of diabetes. Secondary endpoints include all-cause mortality, development of renal and visual impairment, peripheral neuropathy, health service costs, self-reported quality of life, functional status and health utility. Impact of the screening programme at the population level is also assessed through measures of mortality, cardiovascular morbidity, health status and health service use among high-risk individuals. Discussion ADDITION-Cambridge is conducted in a defined high-risk group

  11. 40-Godišnjica institucije Cambridge Crystallographic Data Centre posvećene pohranjivanju podataka o molekularnim i kristalnim strukturama -

    Directory of Open Access Journals (Sweden)

    Molčanov, K.

    2006-06-01

    Full Text Available The article is dedicated to 40th anniversary of The Cambridge Crystallographic Data Centre (CCDC, the world-known centre (http://www.ccdc.cam.ac.uk responsible for deposition and control of crystallographic data, including atomic coordinates that define the three-dimensional structures of organic molecules and metal complexes containing organic ligands. Cambride Structural Database (CSD, one among the first established electronic databases, nowadays is the most significant crystallographic database in the world. CSD has about 400,000 deposited structures. The use of the extensive database, which is growing rapidly, needs support of efficient and sophisticated software for searching, analysing and visualising structural data. The seminal role of CSD in the research related to crystallography, chemistry, material sciences, solid state physics and chemistry, life sciences, pharmacology, and in particular in drug design, has been documented in more than 1300 scientific papers. The important issues of CCDC are the accuracy of deposited data and development of software that enables a wide variety of applications. Such demanding project requires higly competent team of experts; thus the article brings into focus the scientific approach of the team based on the long tradition in crystallography, modelling and informatics. The article is not dedicated to 40th anniversary of the centre only, but it also reveals how Cambridge Structural Database can be used in the research and teaching. The use of electronic media and computer graphics makes “data mining" very efficient and useful but also esthetically appealing due to the molecular architecture. At the Rudjer Bošković Institute, Zagreb, Croatia there is The National Affiliated Centre of Cambridge Crystallographic Data Centre responsible for communication and dissemination of CSD in Croatia, Slovenia and Macedonia. The use of CSD is illustrated by two examples performed and published by the presenting

  12. Assessment of neuropsychological function through use of the Cambridge Neuropsychological Testing Automated Battery: performance in 4- to 12-year-old children.

    Science.gov (United States)

    Luciana, Monica; Nelson, Charles A

    2002-01-01

    In this article, children's performance on subtasks from the Cambridge Neuropsychological Testing Automated Battery (CANTAB) is described. Two samples were recruited, one of which included children who spoke English as a second language. Children in this group also completed subtests from the Wechsler Intelligence Scale for Children-Third Revision (WISC-III). Despite the fact that ESL children scored over 1 SD below the norm on the WISC-III Vocabulary subtest, there were no CANTAB performance distinctions between primary versus secondary English-language speakers. In addition, several aspects of CANTAB performance were significantly correlated with verbal and nonverbal IQ. When developmental trends were examined, findings indicated that several aspects of frontal lobe function (memory span, working memory, and planning skills) are not functionally mature, by the age of 12 years. Implications for use of the CANTAB in clinical studies are discussed. PMID:12661972

  13. Documentation for the machine-readable version of the Fourth Cambridge Radio Survey Catalogue (4C) (Pilkington, Gower, Scott and Wills 1965, 1967)

    Science.gov (United States)

    Warren, W. H., Jr.

    1983-09-01

    The machine readable catalogue contains survey data from the papers of Pilkington and Scott and Gower, Scott and Wills. These data result from a survey of radio sources between declinations -07 deg and +80 deg using the large Cambridge interferometer at 178 MHz. The computerized catalog contains for each source the 4C number, 1950 position, measured flux density, and accuracy class. For some sources miscellaneous brief comments such as cross identifications to the 3C catalog or remarks on contamination from nearby sources are given at the ends of the data records. A detailed description of the machine readable catalog as it is currently being distributed by the Astronomical Data Center is given to enable users to read and process the data.

  14. More on the spider genus Xeropigo O.P.-Cambridge (Araneae, Corinnidae, Corinninae): seven new species and new records from Brazil.

    Science.gov (United States)

    Carvalho, Leonardo S; Shimano, Yulie; Candiani, David F; Bonaldo, Alexandre B

    2016-01-01

    Seven new species of the spider genus Xeropigo O. P.-Cambridge are described from Brazil, increasing the genus member list up to 16 species. X. piripiri n. sp., X. aitatu n. sp., and X. cajuina n. sp. are described from the state of Piauí. X. crispim n. sp. is described from the states of Ceará, Piauí, and Maranhão. X. oxente n. sp. is described from the state of Rio Grande do Norte. X. canga n. sp. is described from the state of Minas Gerais. X. ufo n. sp. is described from the state of Mato Grosso. The geographical distribution of X. tridentiger, X. camilae, X. pachitea, and X. perene is updated. A key to all species of Xeropigo is presented and possible relationships among all species of the genus are discussed. PMID:27395095

  15. The FFC-Cambridge process for the conversion of metal oxides to metals - history, fundamentals, potential application to spent nuclear oxide fuel

    International Nuclear Information System (INIS)

    Molten salts find use in the reprocessing of spent nuclear oxide fuel. In the common approach, the mixed metal oxides of the spent fuel are reduced chemically to the corresponding metals in a melt of LiCI in a two-step process, and the resulting metals are then separated by electro-deposition in a melt of LiCI/KCI. The FFC-Cambridge process is a relatively new metallurgical method, which allows the electrochemical reduction of metal oxides in a melt of CaCI2 in one step. This article summarises the history and fundamentals of the process, and depicts proven applications and potential benefits in spent fuel reprocessing. (author)

  16. Data-driven high-throughput prediction of the 3-D structure of small molecules: review and progress. A response to the letter by the Cambridge Crystallographic Data Centre.

    Science.gov (United States)

    Baldi, Pierre

    2011-12-27

    A response is presented to sentiments expressed in "Data-Driven High-Throughput Prediction of the 3-D Structure of Small Molecules: Review and Progress. A Response from The Cambridge Crystallographic Data Centre", recently published in the Journal of Chemical Information and Modeling, (1) which may give readers a misleading impression regarding significant impediments to scientific research posed by the CCDC. PMID:22107601

  17. Correlates of time spent walking and cycling to and from work: baseline results from the commuting and health in Cambridge study

    Directory of Open Access Journals (Sweden)

    Panter Jenna

    2011-11-01

    Full Text Available Abstract Purpose Environmental perceptions and psychological measures appear to be associated with walking and cycling behaviour; however, their influence is still unclear. We assessed these associations using baseline data from a quasi-experimental cohort study of the effects of major transport infrastructural developments in Cambridge, UK. Methods Postal surveys were sent to adults who travel to work in Cambridge (n = 1582. Questions asked about travel modes and time spent travelling to and from work in the last week, perceptions of the route, psychological measures regarding car use and socio-demographic characteristics. Participants were classified into one of two categories according to time spent walking for commuting ('no walking' or 'some walking' and one of three categories for cycling ('no cycling', '1-149 min/wk' and ' ≥ 150 min/wk'. Results Of the 1164 respondents (68% female, mean (SD age: 42.3 (11.4 years 30% reported any walking and 53% reported any cycling to or from work. In multiple regression models, short distance to work and not having access to a car showed strong positive associations with both walking and cycling. Furthermore, those who reported that it was pleasant to walk were more likely to walk to or from work (OR = 4.18, 95% CI 3.02 to 5.78 and those who reported that it was convenient to cycle on the route between home and work were more likely to do so (1-149 min/wk: OR = 4.60, 95% CI 2.88 to 7.34; ≥ 150 min/wk: OR = 3.14, 95% CI 2.11 to 4.66. Positive attitudes in favour of car use were positively associated with time spent walking to or from work but negatively associated with cycling to or from work. Strong perceived behavioural control for car use was negatively associated with walking. Conclusions In this relatively affluent sample of commuters, a range of individual and household characteristics, perceptions of the route environment and psychological measures relating to car use were associated with

  18. “In my end is my beginning”. Una discussione sul caso trascurato dei Cambridge Ritualists fra antropologia comparativa, filosofia e pensiero scientifico - “In my end is my beginning”. An argument on the Cambridge Ritualists’ neglected case, on the wave of comparative anthropology, philosophy and scientific thought

    Directory of Open Access Journals (Sweden)

    Danila Cinellu

    2015-12-01

    Full Text Available Somehow rounding off an intellectual season in which humanities strongly lament the loss of Darwinian incitements, while exploiting both Wilson’s biophilia hypothesis and Rappaport’s engaged anthropology as springboards, this article wants to cast light on how two anthropologically undervalued manifestos of the Cambridge School – Harrison’s Themis (1912 and Cornford’s From Religion to Philosophy (1912 – laid the foundation of post-modern science. It highlights, in other words, how within evolutionary anthropology, to which we owe the birth of the comparative study of religions, were surreptitiously raised significant issues against eco-systemic disfunctionalities due to the scientific pattern rooted in Atomism and modern Cartesianism itself. In order to counteract the conventional belief that evolutionary anthropology was entirely shaped by the kind of Positivism of Illuministic inspiration, the association between the “mystic” and the “savage” will be once more taken into consideration. In this regard, a quite unreleased focus on Lévi-Strauss’ paradigm “le totémism du dedans” is deemed also essential. As a consequence, the unfairly forgotten Cambridge Ritualists, Harrison and Cornford, will be especially rehearsed in the light of their adoption of the philosophical Bergsonian concept of durée as a means of probing into the monist vision enshrined in the mysteric religion of Ancient Greece. It is basically the special attention allotted to the mystic’s incorporation of a limitless cyclic time which helps us to detect the extent to which both Harrison and Cornford aimed at propounding an ethical anthropology eager to denounce the forward end because of the obdurate human projection outside the sphere of Life itself. What this essay thus propounds is not a rehearsal of the Cambridge School for the sake of it. While advocating cumulative knowledge around the very same foundation of the “scientific study of

  19. Test-retest reliability analysis of the Cambridge Neuropsychological Automated Tests for the assessment of dementia in older people living in retirement homes.

    Science.gov (United States)

    Gonçalves, Marta Matos; Pinho, Maria Salomé; Simões, Mário R

    2016-01-01

    The validity of the Cambridge Neuropsychological Automated Tests has been widely studied, but their reliability has not. This study aimed to estimate the test-retest reliability of these tests in a sample of 34 older adults, aged 69 to 90 years old, without neuropsychiatric diagnoses and living in retirement homes in the district of Lisbon, Portugal. The battery was administered twice, with a 4-week interval between sessions. The Paired Associates Learning (PAL), Spatial Working Memory (SWM), Rapid Visual Information Processing, and Reaction Time tests revealed measures with high-to-adequate test-retest correlations (.71-.89), although several PAL and SWM measures showed susceptibility to practice effects. Two estimated standardized regression-based methods were found to be more efficient at correcting for practice effects than a method of fixed correction. We also found weak test-retest correlations (.56-.68) for several measures. These results suggest that some, but not all, measures are suitable for cognitive assessment and monitoring in this population. PMID:26574661

  20. An investigation into the impact of question structure on the performance of first year physics undergraduate students at the University of Cambridge

    Science.gov (United States)

    Gibson, Valerie; Jardine-Wright, Lisa; Bateman, Elizabeth

    2015-07-01

    We describe a study of the impact of exam question structure on the performance of first year Natural Sciences physics undergraduates from the University of Cambridge. The results show conclusively that a student’s performance improves when questions are scaffolded compared with university style questions. In a group of 77 female students we observe that the average exam mark increases by 13.4% for scaffolded questions, which corresponds to a 4.9 standard deviation effect. The equivalent observation for 236 male students is 9% (5.5 standard deviations). We also observe a correlation between exam performance and A2-level marks for UK students, and that students who receive their school education overseas, in a mixed gender environment, or at an independent school are more likely to receive a first class mark in the exam. These results suggest a mis-match between the problem-solving skills and assessment procedures between school and first year university and will provide key input into the future teaching and assessment of first year undergraduate physics students.

  1. The Calgary-Cambridge Referenced Observation Guides: an aid to defining the curriculum and organizing the teaching in communication training programmes.

    Science.gov (United States)

    Kurtz, S M; Silverman, J D

    1996-03-01

    Effective communication between doctor and patient is a core clinical skill. It is increasingly recognized that it should and can be taught with the same rigour as other basic medical sciences. To validate this teaching, it is important to define the content of communication training programmes by stating clearly what is to be learnt. We therefore describe a practical teaching tool, the Calgary-Cambridge Referenced Observation Guides, that delineates and structures the skills which aid doctor-patient communication. We provide detailed references to substantiate the research and theoretical basis of these individual skills. The guides form the foundation of a sound communication curriculum and are offered as a starting point for programme directors, facilitators and learners at all levels. We describe how these guides can also be used on an everyday basis to help facilitators teach and students learn within the experiential methodology that has been shown to be central to communication training. The learner-centred and opportunistic approach used in communication teaching makes it difficult for learners to piece together their evolving understanding of communication. The guides give practical help in countering this problem by providing: an easily accessible aide-mémoire; a recording instrument that makes feedback more systematic; and an overall conceptual framework within which to organize the numerous skills that are discovered one by one as the communication curriculum unfolds. PMID:8736242

  2. La intervención del derecho penal en materia de bioseguridad: la criminalización de la actividad empresarial biotecnológica de liberación intencional en el ambiente con fines comerciales y de comercialización de productos biotech

    OpenAIRE

    Tanus Job e Meira, Bruno

    2009-01-01

    [ES] El objetivo general del presente trabajo reside en analizar el sistema de control del riesgo biotecnológico relativo a las principales actividades por las cuales se utilizan las empresas biotech en el ámbito agroalimentario, es decir, las conductas de liberación en el ambiente con fines comerciales, así como la comercialización de “organismos modificados genéticamente” (OMGs) y sus derivados. Tales actividades son consideradas como las más importantes en el ámbito mercantil y, efectivame...

  3. Plasma free fatty acids do not provide the link between obesity and insulin resistance or β-cell dysfunction: results of the Reading, Imperial, Surrey, Cambridge, Kings (RISCK) study

    OpenAIRE

    Johns, I.; Goff, L; Bluck, L. J.; Griffin, B. A.; Jebb, S. A.; Lovegrove, J. A. (Julie A.); Sanders, T A B; G. Frost; Dornhorst, A.

    2014-01-01

    Aims To investigate the relationship between adiposity and plasma free fatty acid levels and the influence of total plasma free fatty acid level on insulin sensitivity and β-cell function. Methods An insulin sensitivity index, acute insulin response to glucose and a disposition index, derived from i.v. glucose tolerance minimal model analysis and total fasting plasma free fatty acid levels were available for 533 participants in the Reading, Imperial, Surrey, Cambridge, Kings study. ...

  4. The 'Robbins Circle' of the London School of Economics and Political Science : the Liberalism group' s counterattack of Laissez-faire against Cambridge<人文・社会科学>

    OpenAIRE

    木村, 雄一

    2010-01-01

    The purpose of this paper is to describe the 'Robbins Circle' of the early 1930s at LSE-a miraculous group comprising Lionel Robbins, F. Hayek, N. Kaldor, J. Hicks, A. Lerner, and others-contrasting it with Cambridge economists and elucidating Robbins's perspective. Few reports have explored their theory and policy through Robbins's view. The 'Robbins Circle' supported LSE as the 'international stronghold of the continental economists such as Austrian economics and Lausanne economics as a riv...

  5. Reflections on Cambridge: Wittgenstein's Poker - Lost and Found in Cambridge

    OpenAIRE

    Macfarlane, Alan

    2012-01-01

    A film about the famous poker which featured in an argument between Ludwig Wittgenstein and Karl Popper in the earlier nineteenth century. It was once in the room where Alan Macfarlane (featured here) worked in King's College, and was then lost for thirty years. It has (probably) been found again. Filmed by Xu Bei and Alan Macfarlane in 2009 and 2011 [An error spotted by Youtuber - the argument took place in the earlier C20, not the C19 - apologies!

  6. The Cambridge Companion to Dewey. Cambridge Companions to Philosophy

    Science.gov (United States)

    Cochran, Molly

    2010-01-01

    John Dewey (1859-1952) was a major figure of the American cultural and intellectual landscape in the first half of the twentieth century. While not the originator of American pragmatism, he was instrumental to its articulation as a philosophy and the spread of its influence beyond philosophy to other disciplines. His prolific writings encompass…

  7. Water-quality conditions, and constituent loads and yields in the Cambridge drinking-water source area, Massachusetts, water years 2005–07

    Science.gov (United States)

    Smith, Kirk P.

    2013-01-01

    The source water area for the drinking-water supply of the city of Cambridge, Massachusetts, encompasses major transportation corridors, as well as large areas of light industrial, commercial, and residential land use. Because of ongoing development in the drinking-water source area, the Cambridge water supply has the potential to be affected by a wide variety of contaminants. The U.S. Geological Survey (USGS) has monitored surface-water quality in the Hobbs Brook and Stony Brook Basins, which compose the drinking-water source area, since 1997 (water year 1997) through continuous monitoring and discrete sample collection and, since 2004, through systematic collection of streamwater samples during base-flow and stormflow conditions at five primary sampling stations in the drinking-water source area. Four primary sampling stations are on small tributaries in the Hobbs Brook and Stony Brook Basins; the fifth primary sampling station is on the main stem of Stony Brook and drains about 93 percent of the Cambridge drinking-water source area. Water samples also were collected at six secondary sampling stations, including Fresh Pond Reservoir, the final storage reservoir for the raw water supply. Storm runoff and base-flow concentrations of calcium (Ca), chloride (Cl), sodium (Na), and sulfate (SO4) were estimated from continuous records of streamflow and specific conductance for six monitoring stations, which include the five primary sampling stations. These data were used to characterize current water-quality conditions, estimate loads and yields, and describe trends in Cl and Na in the tributaries and main-stem streams in the Hobbs Brook and Stony Brook Basins. These data also were used to describe how streamwater quality is affected by various watershed characteristics and provide information to guide future watershed management. Water samples were analyzed for physical properties and concentrations of Ca, Cl, Na, and SO4, total nitrogen (TN), total phosphorus (TP

  8. The Cambridge Double Star Atlas

    Science.gov (United States)

    MacEvoy, Bruce; Tirion, Wil

    2015-12-01

    Preface; What are double stars?; The binary orbit; Double star dynamics; Stellar mass and the binary life cycle; The double star population; Detecting double stars; Double star catalogs; Telescope optics; Preparing to observe; Helpful accessories; Viewing challenges; Next steps; Appendices: target list; Useful formulas; Double star orbits; Double star catalogs; The Greek alphabet.

  9. Why raspberries flourish in Cambridge

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Royer, Susanne; Brown, Kerry;

    The activities and role of entrepreneurial milieu in fostering novel products are examined in this research. Creative ideas that initiate disjuncture from prevailing paradigms and form from the aggregation of individuals and concentrated efforts coalescing around a common problem are the subject of...

  10. RFID solution benefits Cambridge hospital.

    Science.gov (United States)

    James, Andrew

    2013-10-01

    Keeping track of thousands of pieces of equipment in a busy hospital environment is a considerable challenge, but, according to RFID tagging and asset tracking specialist, Harland Simon, RFID technology can make the task considerably simpler. Here Andrew James, the company's RFID sales manager, describes the positive benefits the technology has brought the Medical Equipment Library (MEL) at Addenbrooke's Hospital, one of the world's most famous teaching hospitals. PMID:24341115

  11. Falls in advanced old age: recalled falls and prospective follow-up of over-90-year-olds in the Cambridge City over-75s Cohort study

    Directory of Open Access Journals (Sweden)

    Matthews Fiona E

    2008-03-01

    Full Text Available Abstract Background The "oldest old" are now the fastest growing section of most western populations, yet there are scarcely any data concerning even the common problem of falls amongst the very old. Prospective data collection is encouraged as the most reliable method for researching older people's falls, though in clinical practice guidelines advise taking a history of any recalled falls. This study set out to inform service planning by describing the epidemiology of falls in advanced old age using both retrospectively and prospectively collected falls data. Methods Design: Re-survey of over-90-year-olds in a longitudinal cohort study – cross-sectional interview and intensive 12-month follow-up. Participants and setting: 90 women and 20 men participating in a population-based cohort (aged 91–105 years, in care-homes and community-dwelling recruited from representative general practices in Cambridge, UK Measurements: Prospective falls data were collected using fall calendars and telephone follow-up for one year after cross-sectional survey including fall history. Results 58% were reported to have fallen at least once in the previous year and 60% in the 1-year follow-up. The proportion reported to have fallen more than once was lower using retrospective recall of the past year than prospective reports gathered the following year (34% versus 45%, as were fall rates (1.6 and 2.8 falls/person-year respectively. Repeated falls in the past year were more highly predictive of falls during the following year – IRR 4.7, 95% CI 2.6–8.7 – than just one – IRR 3.6, 95% CI 2.0–6.3, using negative binomial regression. Only 1/5 reportedly did not fall during either the year before or after interview. Conclusion Fall rates in this representative sample of over-90-year-olds are even higher than previous reports from octogenarians. Recalled falls last year, particularly repeated falls, strongly predicted falls during follow-up. Similar proportions

  12. Matching biotech needs and yeast physiology

    OpenAIRE

    Passolunghi,

    2009-01-01

    The research in the field of industrial biotechnology, especially regards bioproducts and bioprocesses, are aimed at developing innovative technologies that lead to obtaining compounds with the use of microorganisms, or seeking to enhance existing processes to increase yield, production and productivity, trying to ensure a higher degree of sustainability and reducing environmental impact. To pursue these goals is possible to intervene by adopting a “technologic” approach that includes the...

  13. PROTECTING BIOTECH INVENTIONS: ARE WE READY?

    OpenAIRE

    Namrata Solanki

    2014-01-01

    Biotechnology has been used in agriculture, food production and medicine since the dawn of our civilization. Biotechnology is a popular term for the generic technology of the 21st century. With the advancement in science and research, modern biotechnological inventions have brought a revolution in our lives. These inventions are protected under the Patent Law. The World Trade Organization’s TRIPS agreement sets down the minimum standards for intellectual property regulation for its member cou...

  14. Have Biotech Seeds Increased Maize Yields?

    OpenAIRE

    Xu, Zheng; David A. Hennessy; Moschini, GianCarlo

    2010-01-01

    Corn yield is determined by soils, weather, seed used and other technology choices. Global population and per capita income growth trends as well as demand from the energy sector have placed great stress on cropland use. Global cropland acres and/or yield per acre will need to increase. Whether new seed technologies have enhanced corn yield is a controversial issue. We study U.S. county corn yields 1964-2008, controlling for location effects, fertilization technologies and weather. We find ev...

  15. Genetic resources, biotech patents and gene ownership.

    Science.gov (United States)

    Lucchi, Nicola

    2014-01-01

    Human genetic resources are increasingly considered as ordinary commercial goods, but their value and utility go beyond the simple and immediate private profit. In contrast to other biological resources, commercial use does not focus upon the material itself but rather upon the genetic information it contains. Information goods are then usually subject to intellectual property rights, but in the biological and life science domains, property rights can have a negative influence upon the proper allocation of several goods, including genetic material or goods that are related to it. This scenario reflects the facts of recent litigations in the United States and Europe. In particular, these lawsuits have revived the debate over private ownership and control over genes. Within this context, the objective of the paper is to discuss how to recast the traditional right to access to and use of biochemical and human genetic material currently considered as part of the market framework. Looking beyond the protection of traditional public goods, the paper emphasizes the debate around the progressive commodification of human genetic resources facilitated by an improper use of intellectual property rights. Different scenarios are analyzed to evaluate alternative instruments and new regulatory approaches to avoid the private appropriation of human genetic resources and other natural assets. PMID:25845208

  16. How to start a biotech company.

    Science.gov (United States)

    Tajonar, Adriana

    2014-11-01

    The spirit of life science entrepreneurship is alive and well, with outstanding innovation hubs arising throughout the country and the world. Of note, many of these hubs flourish in close proximity to research universities. If universities are the engine for discovery, then startups are the vehicle for innovation. The creativity and drive of young researchers has the potential to explore novel or underserved applications and revolutionize industries. PMID:25360051

  17. Hb Cambridge-MA [β144(HC1)-β146(HC3)Lys-Tyr-His→0 (HBB c.433 A>T)]: a new high oxygen affinity variant.

    Science.gov (United States)

    Oliveira, Jennifer L; Swanson, Kenneth; Wendt, Patricia; Caughey, Thomas D; Hoyer, James D

    2010-01-01

    A new β hemoglobin (Hb) variant, Hb Cambridge-MA [β144(HC1)β146(HC3)Lys-Tyr-His→0 (AAG>TAG) (HGVS: HBB c.433 A>T] is described. The variant was characterized by high performance liquid chromatography (HPLC), alkaline, acid, globin chain and capillary electrophoresis, isoelectric focusing (IEF), heat and isopropanol stability, p50 analyses, intact globin mass spectrometry (MS) and DNA sequencing. The new variant shows high oxygen (O₂) affinity and is associated with mild polycythemia. PMID:21077764

  18. El Mercat de treball metall-mecànic a Catalunya una anàlisi des de l'Enfocament Segmentacionista de Cambridge per al cas de la comarca d'Osona/

    OpenAIRE

    Gibert, Francesc

    2011-01-01

    Descripció del recurs: La tesi estudia el mercat de treball del sector metall-mecànic a Catalunya. Aquesta anàlisi es realitza des de les aportacions de l'Enfocament Segmentacionista de Cambridge i se centra en el cas de la comarca d'Osona, el qual pot es pot entendre com a representatiu del mercat de treball metall-mecànic català. La metodologia és pluriestratègica d'orientació qualitativa. S'exploten bases de dades d'empreses i la informació documental sobre el sector i territori, i es r...

  19. 17 January 2011 - British (Cambridge) Trustee of the London Science Museum Chair of the Management Committee of the Newton Institute for Mathematical Sciences H. Covington in the LHCB underground experimental area with A. Schopper; signing the guest book with Director for Accelerators and Technology S. Myers; throughout accompanied by R. Veness.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    17 January 2011 - British (Cambridge) Trustee of the London Science Museum Chair of the Management Committee of the Newton Institute for Mathematical Sciences H. Covington in the LHCB underground experimental area with A. Schopper; signing the guest book with Director for Accelerators and Technology S. Myers; throughout accompanied by R. Veness.

  20. 24 January 2012 - British Vice-Chancellor of the University of Cambridge Sir Leszek Borysiewicz signing the guest book with CERN Director-General, visiting ATLAS experimental area with Collaboration Deputy Spokesperson D. Charlton and Sm18 with engineer R. Veness.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    24 January 2012 - British Vice-Chancellor of the University of Cambridge Sir Leszek Borysiewicz signing the guest book with CERN Director-General, visiting ATLAS experimental area with Collaboration Deputy Spokesperson D. Charlton and Sm18 with engineer R. Veness.

  1. Can they recover? An assessment of adult adjustment problems among males in the abstainer, recovery, life-course persistent, and adolescence-limited pathways followed up to age 56 in the Cambridge Study in Delinquent Development.

    Science.gov (United States)

    Jennings, Wesley G; Rocque, Michael; Fox, Bryanna Hahn; Piquero, Alex R; Farrington, David P

    2016-05-01

    Much research has examined Moffitt's developmental taxonomy, focusing almost exclusively on the distinction between life-course persistent and adolescence-limited offenders. Of interest, a handful of studies have identified a group of individuals whose early childhood years were marked by extensive antisocial behavior but who seemed to recover and desist (at least from severe offending) in adolescence and early adulthood. We use data from the Cambridge Study in Delinquent Development to examine the adult adjustment outcomes of different groups of offenders, including a recoveries group, in late middle adulthood, offering the most comprehensive investigation of this particular group to date. Findings indicate that abstainers comprise the largest group of males followed by adolescence-limited offenders, recoveries, and life-course persistent offenders. Furthermore, the results reveal that a host of adult adjustment problems measured at ages 32 and 48 in a number of life-course domains are differentially distributed across these four offender groups. In addition, the recoveries and life-course persistent offenders often show the greatest number of adult adjustment problems relative to the adolescence-limited offenders and abstainers. PMID:26027850

  2. A combined theoretical and Cambridge Structural Database study of π-hole pnicogen bonding complexes between electron rich molecules and both nitro compounds and inorganic bromides (YO2Br, Y = N, P, and As).

    Science.gov (United States)

    Bauzá, Antonio; Ramis, Rafael; Frontera, Antonio

    2014-04-17

    Quantum calculations at the DFT-D3/def2-TZVPD level of theory have been used to examine complexes between O2YBr (Y═N, P, and As) molecules and several Lewis bases, that is, NH3, H2O, and HF. The interactions of the lone pair of the ammonia, water, and hydrogen fluoride with the σ-hole and π-hole of O2YBr molecules have been considered. In general, the complexes where the Lewis base lone pair interacts with the π-hole are more favorable than those with σ-hole. The nature of the interactions has been characterized with the Bader theory of atoms in molecules (AIM). We have also studied the ability of trifluoronitromethane and nitromethane to interact with anions using their π-hole along with an analysis the Cambridge Structural Database. We have found a large number of hits that provide strong experimental support for ability of the nitryl (-NO2) group to interact with anions and Lewis bases. In some X-ray structures, the π-hole interaction is crucial in the crystal packing and has a strong influence in the solid state architecture of the complexes. Finally, due to the relevance in atmospheric chemistry, we have studied noncovalent σ/π-hole complexes of nitryl bromide with ozone. PMID:24679186

  3. The Cambridge companion to fantasy literature

    OpenAIRE

    2015-01-01

    "Fantasy is a creation of the Enlightenment and the recognition that excitement and wonder can be found in imagining impossible things. From the ghost stories of the Gothic to the zombies and vampires of twenty-first-century popular literature, from Mrs Radcliffe to Ms Rowling, the fantastic has been popular with readers. Since Tolkien and his many imitators, however, it has become a major publishing phenomenon. In this volume, critics and authors of fantasy look at the history of fantasy sin...

  4. Schools and Delinquency. Cambridge Criminology Series.

    Science.gov (United States)

    Gottfredson, Denise C.

    This book links theory and empirical evidence to derive implications for designing school-based delinquency prevention programs. It examines how school environment and behavior interact, discusses the multiple levels of influence in and around schools that combine with student characteristics to lead to delinquency, and addresses the malleability…

  5. The Cambridge handbook of physics formulas

    International Nuclear Information System (INIS)

    Full text: Writing a review of a handbook of formulas is an interesting exercise in itself. By its very nature, one cannot read a handbook through from cover to cover. In writing such a review, as in many other assessments (e.g. quality of research and of education) it is common to concentrate on those things which are easiest to quantify, even if they are not really relevant to the quality of what one is purporting to assess or, as Hamming (1997 The Art of Doing Science and Engineering (Learning to Learn) (Amsterdam: Gordon and Breach) ISBN 90 5699 501 4) puts it, 'Of the things you can choose to measure some are hard, firm measurements such as height and weight, while some are soft such as social attitudes. There is always a tendency to grab the hard, firm measurement, though it may be quite irrelevant as compared to the soft one.' Following this practice, I start by assessing in detail some points which are easily quantifiable, even if of minor relevance. Most of the book is devoted to equations, but there are some tables. The periodic table stops at element 103 lawrencium). Several heavier elements have been known for over a decade. The author provides the Greek alphabet but not the Russian nor the Hebrew. These would be more useful than tabulating the values of pi () and e to 1000 places, which most of us can generate on our desk-top computers faster than looking them up. Several pages are given to names of units and their values in SI units. It is fun to find out how large a firkin is, and that it has different values in the UK (9 gallons) and US (9.8 US gallons). However, like so many of the older units it has a number of different values. According to Stephen Dresner (1971 Units of Measurement (Aylesbury: Harvey Miller and Metcalf Ltd) ISBN 85602 036 2) a firkin of butter weighs 56 lb and a firkin of soap 64 lb. I should not be surprised to learn that firkins of other commodities had yet other values nor, indeed, that there might be regional differences. I do think that if such quantities are to be mentioned, their imperial value should be given as well as the SI value. One of my favourite metric units is not included: the glug (the cgs equivalent of the imperial unit of mass, the slug). There are tables of electron, proton, neutron and muon constants but, surprisingly, none for quarks, nor for any others in the particle physics menagerie. The formulae given for least squares are readily available in many texts. It is a pity that the author did not include formulae for fitting a straight line to data with uncertainties in both x and y values. (I must declare an interest, as co-author of two papers on this topic published in this journal: Borcherds P H and Sheth C V 1995 Least squares fitting of a straight line to a set of data points Eur. J. Phys. 16 204-10; Sheth C V, Ngwengwe A and Borcherds P H 1997 Least squares fitting of a straight line to a set of data points: II Parameter variances Eur. J. Phys. 17 322-6.) The handbook contains very few references: perhaps more will be included in a future edition. The coverage of this book is wide and, based on a random sample, accurate. It is also up to date in some areas, for example the Feigenbaum constants (of the nonlinear period doubling cascade) are specified. The advice of the author on how to use this handbook is to start by using the index rather than by flicking through the pages. I have done both, and the indexing is good. In his preface the author writes 'It is intended to be useful rather than pedagogically complete, so that students can use it for revision and for structuring their knowledge once they understand the physics.' I think the author has achieved his aim, and produced a book which should be in every physics library, and which professional physicists as well as students should think of adding to their personal libraries. (author)

  6. Fifty years ago - nuclear physics at Cambridge

    International Nuclear Information System (INIS)

    Fifty years ago, the Cavendish saw the first nuclear transformations using artificially accelerated particles, and was soon to provide confirmation of the discovery of the positron. In 1932, the Cavendish Laboratory under the guiding hand of Rutherford was a world focus for research and with these discoveries saw the birth of modern particle physics. (orig.).

  7. 以研究證據為基礎之多媒體學習理論:劍橋多媒體學習手冊之分析 Book Review: The Cambridge Handbook of Multimedia Learning

    Directory of Open Access Journals (Sweden)

    黃淑玲 Shu-Ling Huang

    2011-03-01

    Full Text Available 早期以單機、個人電腦為主的電腦輔助教學,其教學原理大多採用行為主義的概念進行設計;自1990 年代起網際網路快速發展,興起網際網路教學、遠距教學的研究,此階段適逢教育界強調建構主義教學概念,各種以建構主義為基礎的學習模式亦廣泛被應用於網路的學習環境中,如合作學習、情境學習、自我導向學習等。換言之,這時期的研究大都是借用教育心理學的理論,進行探討網路學習的成效,尚未建構數位學習的理論架構。在數位學習研究的氛圍下,認知心理學學者Mayer亦將其研究的焦點從實體課程的學習轉向多媒體學習,並將研究結果建構為多媒體學習理論,於2001 年出版Multimedia Learning 一書,之後與Clark 合著e-Learning and the Science of Instruction;2005 年整合其多年的研究結果並邀請相關多媒體研究學者,出版The Cambridge Handbook of Multimedia Learning 一書,本書可謂以研究證據為基礎(evidence-based)所建構的多媒體學習手冊,作者以實證研究為基礎,發展多媒體環境中的學習理論,以分析人類如何進行文字(包括印刷文字或口述文本)與圖像(包括插圖、圖表、照片、地圖、動畫或錄影帶)的學習,以及不同媒體呈現方式對學習的影響,同時分析了如何進行多媒體教學設計及如何運用多媒體在不同領域的學習中。

  8. The Industrial Application Requirement for Biotech Inventions in Europe

    DEFF Research Database (Denmark)

    Minssen, Timo; Nilsson, David

    2016-01-01

    New Research CollectionEuropean Intellectual Property Law. Edited by Jan Rosén, Stockholm University and former ATRIP President. This one volume collection thoroughly covers and systematically displays the three main areas of Intellectual Property (IP) Law - Patents, Trademarks and Copyright - wi...

  9. Exploring Business Models for SMEs in the Biotech Industry

    OpenAIRE

    Holm-Bergqvist, Linus; Ödmark, Victor

    2013-01-01

    The interest in business models has lately increased, which could be traced back to the dot-com burst during the 2000s. There exists no general definition of business models. Howev-er, researchers all agree that business models are used to illustrate the design and architec-ture of the value creation process of companies. Today’s research of business models has mainly been focused on e-commerce. This thesis contributes to the research of business models by extending the research to focus on S...

  10. RNA triplexes: from structural principles to biological and biotech applications.

    Science.gov (United States)

    Devi, Gitali; Zhou, Yuan; Zhong, Zhensheng; Toh, Desiree-Faye Kaixin; Chen, Gang

    2015-01-01

    The diverse biological functions of RNA are determined by the complex structures of RNA stabilized by both secondary and tertiary interactions. An RNA triplex is an important tertiary structure motif that is found in many pseudoknots and other structured RNAs. A triplex structure usually forms through tertiary interactions in the major or minor groove of a Watson-Crick base-paired stem. A major-groove RNA triplex structure is stable in isolation by forming consecutive major-groove base triples such as U·A-U and C(+) ·G-C. Minor-groove RNA triplexes, e.g., A-minor motif triplexes, are found in almost all large structured RNAs. As double-stranded RNA stem regions are often involved in biologically important tertiary triplex structure formation and protein binding, the ability to sequence specifically target any desired RNA duplexes by triplex formation would have great potential for biomedical applications. Programmable chemically modified triplex-forming oligonucleotides (TFOs) and triplex-forming peptide nucleic acids (PNAs) have been developed to form TFO·RNA2 and PNA·RNA2 triplexes, respectively, with enhanced binding affinity and sequence specificity at physiological conditions. Here, we (1) provide an overview of naturally occurring RNA triplexes, (2) summarize the experimental methods for studying triplexes, and (3) review the development of TFOs and triplex-forming PNAs for targeting an HIV-1 ribosomal frameshift-inducing RNA, a bacterial ribosomal A-site RNA, and a human microRNA hairpin precursor, and for inhibiting the RNA-protein interactions involving human RNA-dependent protein kinase and HIV-1 viral protein Rev. PMID:25146348

  11. North Carolina's Approach: Developing a Bio-Tech Workforce

    Science.gov (United States)

    Smit, Norman

    2004-01-01

    States across the country are all chasing what are becoming known as "new-age" technologies. These are technologies such as biotechnology, nanotechnology, bio-informatics and others. These technologies offer the potential for long-term economic growth and well-paid jobs to employees working in these sectors. As these technologies mature,…

  12. Hunger Fighters See Biotech Hope for Poor Nations

    Institute of Scientific and Technical Information of China (English)

    Julie; Ingwersen; 钱民徵

    2002-01-01

    基因,转基因,基因工程……与“基因”有关的这几个词,几乎成了上世纪末以来的热门词语。这似乎印证了“21世纪属于生物学世纪”这一著名预言。“genetically modified(GM)crops”也成了一个英语热门词汇。本文详细介绍了上世纪六、七十年代所谓绿色革命之父,诺贝尔奖获得者Norman Borlaug对(GM)crops这场新革命的观点。他的观点有两点值得我们关注: 1/为什么当今世界有人反对这场崭新意义的绿色革命?Borlaug的观点非常犀利: If we sit in Europe or North America and decide that because we don’t need that scientific approach for our food supply, therefore they can’t have it either, that is grossly (非常) unethical (不道德的). 2/凡是革命。那就必然会有风险:no agricultural advance is risk-free. Borlaug称,当年的绿色革命也同样遭受了人们的反对:Critics(批评家们)in the past accused the Green Revolution of popularizing (普及) chemical fertilizers, pesticides and irrigation that jeopardized (危害) the environment in developing countries.】

  13. Biotechnology regulation: limiting or contributing to biotech development?

    DEFF Research Database (Denmark)

    Hansen, Anne Grethe

    2001-01-01

    Modern biotechnology has been characterized by being surrounded by scientific and public debate and by interest conflicts. An early Danish debate and regulation has been criticized for inhibiting or retarding development and thus growth. Though much regulation and debate have been transferred to...

  14. Licensing biotech intellectual property in university-industry partnerships.

    Science.gov (United States)

    Drozdoff, Vladimir; Fairbairn, Daryl

    2015-03-01

    Appropriate negotiation and drafting of license agreements are critical to successfully establishing and managing the expansive and complex relationships that are becoming more common between industry and universities. More often than not, the resulting licensing agreements become quite lengthy and complex, and the key principles become difficult to discern among all the details. This summary provides a short, nonexhaustive introduction to some of the essential components of these licenses with the intent of providing the non-licensing professional a better appreciation of some of the key commercial and legal terms from both an academic and company perspective, keeping in mind some of the considerations that particularly apply to biotechnology deals. PMID:25605752

  15. Evaluation and Audience Acceptance in Biotech News Texts

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte; Vestergaard, Torben

    2009-01-01

    features by analysing the coverage of the biotechnology debate in one of the largest Danish newspapers, Politiken, during the first 9 months of 2004. The aim of this analysis is to uncover how seemingly objective and ‘neutral' accounts of events and state of affairs can be used by journalists to...... significantly influence the attitudes of the readership. In the analysis, it is shown that the feature Judgement (of people) is virtually absent, whereas Appreciation (of things) is quite frequent, reflecting the fact that the perceived risk factor associated with biotechnology was paramount in the said period...

  16. Religion and Culture in Medieval Islam. Cambridge UK, Cambridge University Press, 1999, 120 p.

    OpenAIRE

    Lory, Pierre,

    2010-01-01

    Il s’agit du quatorzième volume des publications d’actes des conférences données à l’occasion de l’attribution de la médaille Giorgio Levi Della Vida à un savant s’étant distingué dans le domaine des études sur la civilisation islamique, et décerné en 1993 à George Makdisi. Il inclut le texte de sept interventions portant sur le thème, très large, donné par le titre. Dans l’une d’elles, G. Makdisi résume sa théorie sur l’origine musulmane de l’enseignement scholastique en Europe médiévale d’O...

  17. (Review of) Reno, William. 2011. Warfare in Independent Africa. Cambridge: Cambridge University Press

    DEFF Research Database (Denmark)

    Hagmann, Tobias

    2013-01-01

    Warfare in Independent Africa is Reno’s bold attempt to analyze the modern history of African insurgencies. The book tackles this task through the prism of five generations of rebel, which left their mark on the continent; anti-colonial rebels, majority rule rebels, reform rebels, warlord rebels ...

  18. NewsMars: Express journey to Mars ASE 2003: Knocked out by meteorites Events: Sun-Earth Day ASE 2003: Fun Physics - popular as ever Appointments: Sykes to bring science to the people UK Science Education: The future's bright, the future's science ASE 2003: A grand finale for Catherine Teaching Resources: UK goes to the planets Cambridge Physics Update: Basement physics Conferences: Earth Science Teachers' Association Conference 2003 New Website: JESEI sets sail GIREP: Teacher education seminar Malaysia: Rewards for curriculum change Cambridge Physics Update: My boomerang will come back! Teaching Resources: Widening particiption through ideas and evidence with the University of Surrey Wales: First Ffiseg Events: Nuna: Solar car on tour Physics on Stage: Physics on Stage 3 embraces life Symposium: In what sense a nuclear 'debate'? Gifted and Talented: Able pupils experiencing challenging science Australia: ISS flies high Down Under

    Science.gov (United States)

    2003-03-01

    Mars: Express journey to Mars ASE 2003: Knocked out by meteorites Events: Sun-Earth Day ASE 2003: Fun Physics - popular as ever Appointments: Sykes to bring science to the people UK Science Education: The future's bright, the future's science ASE 2003: A grand finale for Catherine Teaching Resources: UK goes to the planets Cambridge Physics Update: Basement physics Conferences: Earth Science Teachers' Association Conference 2003 New Website: JESEI sets sail GIREP: Teacher education seminar Malaysia: Rewards for curriculum change Cambridge Physics Update: My boomerang will come back! Teaching Resources: Widening particiption through ideas and evidence with the University of Surrey Wales: First Ffiseg Events: Nuna: Solar car on tour Physics on Stage: Physics on Stage 3 embraces life Symposium: In what sense a nuclear 'debate'? Gifted and Talented: Able pupils experiencing challenging science Australia: ISS flies high Down Under

  19. "Estudiar el estado" en State in Society: Studying How States and Societies Transform and Constitute One Another, Cambridge Studies in Comparative Politics, Cambridge University Press, Cambridge, 2001.

    Directory of Open Access Journals (Sweden)

    Joe S. MIGDAL

    2008-06-01

    Full Text Available A lo largo del siglo XX los asuntos centrales para los politólogos  dedicados a la política comparada han cambiado muy poco. Desde Weber y Gramsci hasta Almond, Verba o Skocpol, sus preocupaciones se han centrado en por qué la gente obedece y qué tipo de estructuras y culturas facilitan la obediencia y el comportamiento conformista. Los elementos que los politólogos han singularizado en sus investigaciones como las claves para comprender la obediencia y la conformidad han incluido a los sospechosos habituales: los parlamentos, las burocracias, el liderazgo gubernamental, los tribunales y las leyes, y la policía y los militares. Estos forman las partes constitutivas y los parámetros de la estructura compleja y de alguna manera escurridiza a la que llamamos estado moderno —la montaña que tarde o temprano todos los politólogos tienen que escalar—. Over the course of the twentieth century, comparative political scientists’ core questions have changed very little. From Weber and Gramsci to Almond, Verba and Skocpol, their concerns have centred on why people obey and on what sorts of structures and cultures facilitates obedience and conformist behaviour. The elements that political scientists have singled out for investigation as the key to understanding obedience and conformity have included the usual suspects: parliaments, Bureaucracies, governmental leadership, courts and law, and police and military. These form the constituent part and parameters of that complex and somewhat elusive structure called the modern state —the mountain that all political scientists sooner or later must climb.

  20. Comparison of four enzyme immunoassays for detection of human T-cell lymphotropic virus type 2 antibodies.

    OpenAIRE

    Gallo, D; Yeh, E T; Moore, E S; Hanson, C V

    1996-01-01

    Four licensed enzyme immunoassay (EIA) kits for the measurement of antibody to human T-cell lymphotropic virus (HTLV) type 1, one from Organon Teknika Corp. (OTC), one from Cambridge Biotech Corp. (CBC), and two from Abbott Laboratories (the 1993 modification [Abb 93] and the 2.0 version licensed in 1995 [Abb 95]), were evaluated for sensitivity and specificity in the detection of HTLV type 2 antibody, and the results were compared with those previously obtained with earlier kit versions. The...

  1. 收编文类:中国文学史编写的体例问题--从《剑桥中国文学史》谈起%Incorporating the Literary Genres:The Issue of Stylistic Rules Regarding the Writing and Editing of Chinese Literary Histories:On The Cambridge History of Chinese Literature

    Institute of Scientific and Technical Information of China (English)

    蒋金珅

    2015-01-01

    The writing and editing of Chinese literary histories have since the twentieth century evolved from the orientation by way of literary genres to the axis of times. The tradition of“schools of writing”remains invisible with the modern concept that“each generation has its own literature”with the result that literary genres are included in literary histories focusing on times. The stylistic rules regarding the writing and editing of literary histories in the Republic of China were reconfirmed and solidified after the founding of the People’s Republic of China until The Cambridge History of Chinese Literature was published, which gave rise to a new round of thinking in regard to the stylistic rules about literary histories.%20世纪以来,中国文学史编写经历了由文体导向,转为时代为轴。“文章流别”传统在近代以来“一代有一代文学”的观念下隐匿不现,文体类别被收编在时代为主的文学史中。民国时形成的文学史编写体例在建国后又得到确认和固化,直到《剑桥文学史》出现,又重新引发对文学史体例的新一轮思考。

  2. Ira B. Nadel, ed. The Cambridge Companion to Ezra Pound.

    OpenAIRE

    Axel Nesme

    2006-01-01

    Il s’agit ici, dans l’espace de 300 pages fort denses, de proposer au public une introduction à l’œuvre poundienne dans une perspective aussi bien littéraire, esthétique, philologique que politique et idéologique. L’ouvrage ne visant pas à esquisser un panorama des lectures critiques possibles, aucune orientation théorique n’est privilégiée. L’article de G. Bornstein examine l’interaction entre Pound et Yeats, H.D., T.S. Eliot et James Joyce de 1908 à 1925, placée sous le signe de la coopérat...

  3. Michael Levenson (dir.), The Cambridge Companion to Modernism

    OpenAIRE

    Touya, Aurore

    2014-01-01

    Tous les auteurs ayant collaboré à l’ouvrage dirigé par Michael Levenson soulignent d’emblée le caractère mouvant, approximatif de la notion de modernism : l’introduction, qui fait coïncider le modernism avec les trente premières années du xxe siècle, semble démentir la chronologie qui l’a précédée, qui rappelle les dates de création des grandes œuvres modernistes sur une période allant de 1890 à 1939. Cette première contradiction apparente est bien à l’image des difficultés inhérentes à cett...

  4. Masters of Theory Cambridge and the Rise of Mathematical Physics

    CERN Document Server

    Warwick, Andrew

    2011-01-01

    Winner of the the Susan Elizabeth Abrams Prize in History of Science.When Isaac Newton published the Principia three centuries ago, only a few scholars were capable of understanding his conceptually demanding work. Yet this esoteric knowledge quickly became accessible in the nineteenth and early twentieth centuries when Britain produced many leading mathematical physicists. In this book, Andrew Warwick shows how the education of these "masters of theory" led them to transform our understanding of everything from the flight of a boomerang to the structure of the universe. Warwick focuses on Cam

  5. Mean Streets: Youth Crime and Homelessness. Cambridge Criminology Series.

    Science.gov (United States)

    Hagan, John; McCarthy, Bill

    This study explores the social worlds of homeless children in two Canadian cities, Toronto and Vancouver, comparing them with the environments of in-home and in-school children from the perspective of the children. Samples of 390 and 482 children were interviewed. The following chapters are included: (1) "Street and School Criminologies"; (2)…

  6. Heidelberg y Cambridge: historia de dos departamentos universitarios.

    Directory of Open Access Journals (Sweden)

    Germán E Berrios

    2000-01-01

    Full Text Available Discurso de aceptación del Profesor Germán E. Berrios al recibir el Título Honorario de Doctor en Medicina de la Facultad de Medicina de Ruprecht-Karls, Heidelberg, ante el Rector Magnífico y las Autoridades de la Universidad, el 15 de enero de 1998.

  7. Stephanie Lynn Budin: The Myth of Sacred Prostitution in Antiquity. Cambridge u.a.: Cambridge University Press 2008. Stephanie Lynn Budin: The Myth of Sacred Prostitution in Antiquity. Cambridge u.a.: Cambridge University Press 2008.

    Directory of Open Access Journals (Sweden)

    Julian Herbert Köck

    2010-03-01

    Full Text Available Stephanie Lynn Budin liefert mit vorliegender Studie einen wichtigen Beitrag zur Debatte um die Existenz von Tempelprostitution im Altertum. Systematisch untersucht sie die Quellen zur Tempelprostitution und kann weitgehend überzeugend darlegen, dass die betreffenden Stellen nicht für die Existenz von Tempelprostitution im Altertum sprechen, sondern nur aufgrund von tendenziösen Interpretationen so verstanden wurden. Dabei greift die Studie die Ergebnisse anderer Wissenschaftler/-innen auf, bietet aber – besonders zu Herodot und Strabon – auch neue Erkenntnisse.Stephanie Lynn Budin’s study offers up an important contribution to the debate on the existence of temple prostitution during antiquity. She systematically examines the sources on temple prostitution and can demonstrate, fairly convincingly, that the passages in question do not prove the existence of temple prostitution during antiquity, but instead have been merely understood to do so based on tendentious interpretations. In so doing, the study takes up conclusions offered by other scholars, but it also provides – especially when it comes to Herodotus and Strabo – new insights.

  8. Martyrdom in Islam. Cambridge/New York/Melbourne, Cambridge University Press, 2007, 206 p. (Themes in Islamic History, 4)

    OpenAIRE

    Feuillebois-Piérunek, Ève

    2013-01-01

    Le martyre en islam a été récemment associé aux attentats suicides. D. C. montre que ce type d’attitude est radicalement éloigné de la définition classique du martyre qui condamne le suicide et attribue le statut de martyr à toute personne morte en musulmane. La définition du martyre en Islam a évolué dans l’histoire en fonction des circonstances. Le livre s’intéresse aux premières discussions sur le martyre, aux définitions légales et aux récompenses accordées aux martyrs, aux différences de...

  9. Sundkler, Bengt & Steed, Christopher. -- A History of the Church in Africa. Cambridge, Cambridge University Press, 2000, 1 232 pages.

    OpenAIRE

    Salvaing, Bernard

    2003-01-01

    Cette monumentale étude comble une lacune. Certes il existait déjà un catalogue des missions présentes en Afrique avec l'ouvrage de C. P. Groves, The Planting of Christianity in Africa, (4 vols, London, 1948-1958) et le lecteur francophone trouvait également des données non négligeables dans les chapitres consacrés aux missions des différents volumes de l'Histoire du christianisme des origines à nos jours (Paris 1990-2000, dir. Charles & Luce Pietri, J.-M. Mayeur et al.). Mais nous avo...

  10. The reliability and validity of the Chinese version of the Cambridge Prospective Memory Test with Chinese brain injured patients%中文版剑桥前瞻性记忆测试量表的信度和标准效度研究

    Institute of Scientific and Technical Information of China (English)

    罗子芮; 窦祖林; 郑金利; 陈颖蓓

    2009-01-01

    目的 探讨中文版剑桥前瞻性记忆测试(C-CAMPROMPT)用于评估中国脑损伤患者的各种信度和标准效度.方法 按程序将英文版剑桥前瞻性记忆测试(CAMPROMPT)翻译成中文.30例"正常人"作为信度组和39例临床观察发现存在记忆功能障碍的脑损伤患者作为效度组入选本研究.采用相关分析、Cronbach α系数法分析量表的重测信度、测试者间信度、复本信度、同质性信度及标准效度.结果 信度测试的相关系数和Cronbach α系数为0.697~0.951.效度分析结果显示,C-CAMPROMPT总分和基于事件任务得分与Rivermead行为记忆测试(RBMT)各领域得分呈正相关,基于时间任务与中文版Stroop字-颜色测试(C-SCWT)回溯性记忆任务得分呈负相关.结论 C-CAMPROMPT具有良好的信度和效度,可用于临床评估中国脑损伤患者的前瞻性记忆功能.%Objective To evaluate the reliability and criteria validity of the Chinese Cambridge Prospective Memory Test (C-CAMPROMPT) for testing Chinese patients with acquired brain injury. Methods The CAMPROMPT was translated into Chinese. The translated Version was then used with 30 'normal persons' and 39 with acquired brain injury and memory problems. Correlation analysis and Cronbach's a were used to evaluate reliability and criteria validity of the C-CAMPROMPT. Results Correlation and Cronbach's a were in the range 0.697 to 0.951.The total and event-based scores were positively corrlated with all three field Chinese Version of Rivermead Behavior Memory Test scores. Time-based C-CAMPROMPT scores,however,were negatively correlated with Chinese Version of the Stroop Word-Color Test results. Conclusion The reliability and validity of the C-CAMPROMPT were high enough to be used to test the prospective memory of acquired brain injury patients in the clinic.

  11. 剑桥神经心理自动化成套测试在偏执型精神分裂症与双相躁狂患者中的应用%Preliminary application of the Cambridge Neuropsychological Test Automated Battery in patients with paranoid schizophrenia and bipolar miana in China

    Institute of Scientific and Technical Information of China (English)

    崔立谦; 陈壮飞; 蒋莉君; 邓伟; 黄朝华; 李名立; 王强; 马小红; 李涛

    2011-01-01

    Objective To detect the patterns of cognitive impairment between patients with paranoid schizophrenia and patients with bipolar mania by using the Cambridge Neuropsychological Test Automated Battery (CANTAB) ,and to explore research clues for finding of cognitive endophenotype in patients with paranoid schizophrenia or bipolar mania. Methods Six CANTAB subtests and the seven subtests of the Wechsler Abbreviated Scale of Intelligence (WAIS short form) were administered to 35 patients with paranoid schizophrenia and 33 patients with bipolar mania who were drug naive experiencing an acute episode, as well as 30 healthy controls. Results Patients with paranoid schizophrenia and bipolar mania demonstrated impairments in 13 of the 15 cognitive indicators in CANTAB. After controlling IQ, both patient groups remained as significantly different from normal controls in terms of search strategy(36. 8 ±3.56,37.24 ±4. 21,30. 33 ±6.24) ,between-search errors(40. 86 ± 19.97,40.24 ± 18.92,15.4 ±17.22) on the SWM test,the proportion of hits(0.54 ±0. 18,0.56 ±0.15,0.78 ± 0.17) on the RVIP test,total errors(45.26 ±36.36,46.61 ±33.32,14 ± 11.7) and EDS errors (12.43 ±9.96, 13.18 ±8.98,4.97 ±6.09)on the IED test. Between search error in the SWM test was positively correlation with YMRS scores ( r=0.38, P=0.039) in bipolar patients. Conclusion Both patient groups demonstrated a comparable profile of cognitive impairments during active periods of their condition. The cognitive impairment index may be a discreet cognitive endophenotype overlapping the disorders.%目的 使用剑桥神经心理自动化成套测试(CANTAB)对偏执型精神分裂症与双相躁狂患者认知功能进行比较研究,为寻找认知内表型指标提供线索.方法 采用韦氏智力测试7项简版和CANTAB中的6项分测验对35例未服药、急性期偏执型精神分裂症患者、35例双相躁狂患者和30例正常对照进行测试,通过控制或不控制IQ对认知

  12. The Evolution of the French Public Policy to Promote Biotech Innovation : The Case of Genomics

    OpenAIRE

    Branciard, Anne; Mangematin, Vincent

    2001-01-01

    Working Paper European Biotechnology companies and public policy-makers face to a number of crucial problems related to the development of Biotechnology in Europe : European industrial competitiveness, the relative under-exploitation of the European science base in Biotechnology, poor technology transfer mechanisms and difficulties in starting 'spin-off' firms. The aim of this paper on innovation in genomics and biomedical related biotechnologies is to study the relative impact of the diff...

  13. Blueprints for green biotech: development and application of standards for plant synthetic biology.

    Science.gov (United States)

    Patron, Nicola J

    2016-06-15

    Synthetic biology aims to apply engineering principles to the design and modification of biological systems and to the construction of biological parts and devices. The ability to programme cells by providing new instructions written in DNA is a foundational technology of the field. Large-scale de novo DNA synthesis has accelerated synthetic biology by offering custom-made molecules at ever decreasing costs. However, for large fragments and for experiments in which libraries of DNA sequences are assembled in different combinations, assembly in the laboratory is still desirable. Biological assembly standards allow DNA parts, even those from multiple laboratories and experiments, to be assembled together using the same reagents and protocols. The adoption of such standards for plant synthetic biology has been cohesive for the plant science community, facilitating the application of genome editing technologies to plant systems and streamlining progress in large-scale, multi-laboratory bioengineering projects. PMID:27284031

  14. Who benefits from gm crops? Feeding the biotech giants, not the world's poor

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Villar, J.; Freese, B.; Holder, H.; Chandrasekaran, K.; Rodriguez, L.

    2009-02-15

    The biotechnology industry has aggressively touted GM as a solution to hunger and the global food crisis. Their arguments have been accepted by many politicians. This Friends of the Earth International (FoEI) report looks behind the spin and exposes the reasons why GM crops cannot, and are unlikely to ever, contribute to poverty reduction, global food security or sustainable farming (authors' abstract)

  15. Research in Undergraduate Instruction: A Biotech Lab Project for Recombinant DNA Protein Expression in Bacteria

    Science.gov (United States)

    Brockman, Mark; Ordman, Alfred B.; Campbell, A. Malcolm

    1996-06-01

    In the sophomore-level Molecular Biology and Biotechnology course at Beloit College, students learn basic methods in molecular biology in the context of pursuing a semester-long original research project. We are exploring how DNA sequence affects expression levels of proteins. A DNA fragment encoding all or part of the guanylate monokinase (gmk) sequence is cloned into pSP73 and expressed in E. coli. A monoclonal antibody is made to gmk. The expression level of gmk is determined by SDS gel elctrophoresis, a Western blot, and an ELISA assay. Over four years, an increase in enrollment in the course from 9 to 34 students, the 85% of majors pursuing advanced degrees, and course evaluations all support the conclusion that involving students in research during undergraduate courses encourages them to pursue careers in science.

  16. Vers une écologie « biotech » ?

    OpenAIRE

    Delord, Julien

    2010-01-01

    Si ces dernières années, l’idée de recréer des espèces disparues à partir de leur ADN fossile a enthousiasmé les amateurs de science-fiction, la réalisation de projets de cette nature est aujourd’hui considérée avec le plus grand sérieux par certains écologistes. Ainsi, pendant que l’on séquence de l’ADN de mammouth au Muséum National d’Histoire Naturelle à Paris (Debruyne et al. 2003) ou de l’ADN d’ours des cavernes à Lyon (Orlando 2005), une équipe australienne lève plusieurs millions de do...

  17. Biotech cementitious materials : some aspects of an innovative approach for concrete with enhanced durability

    OpenAIRE

    Torgal, Fernando Pacheco; Labrincha, J. A.

    2013-01-01

    The deterioration of reinforced concrete structures is a very common problem due to the fact that this material has a high permeability which allows water and other aggressive media to enter, thus leading to corrosion problems. The use of sealers is a common way of contributing to concrete durability. However, the most common ones are based on organic polymers which have some degree of toxicity. The Regulation (EU) 305/2011 related to the Construction Products Regulation emphasize...

  18. 2012 in review - part II: overcoming the obstacles in the pharma/biotech industry.

    Science.gov (United States)

    Rabasseda, X; Dulsat, C; Navarro, D; Cruces, E; Graul, A I; Jago, C; Tracy, M

    2013-02-01

    As highlighted in the first part of this review published last month, the year 2012 saw the approval of a remarkable number of new drugs, and among the new drugs reaching the market, a significant proportion were orphan drugs developed for treating less prevalent diseases. These drugs are certainly not expected to become blockbusters, but are of high interest because of their efficacy in a narrow spectrum of patients. This trend aligns with the general tendency of staying away from fit-for-all blockbusters into personalized medicine as one of the strategies for overcoming the patent cliff that resulted in a long list of drugs going off patent and being approved as generics also during last year. The emerging scenario resulting from new developments in the form of new drugs and biosimilars and newly available generic medications paralleled by strategic movements within the pharmaceutical industry to reinforce their position in the market, as reflected by merger and acquisition deals accompanied by significant efforts into prioritization resulting in spin-off and split transactions, is reviewed in this second part. This paper includes a significant amount of data in tables for quick review and to profile the new strategic movements in drug pipelines. Further information, including details on mechanisms of action, current status, itemized pharmacology, pharmacokinetic and clinical trial research findings and updated information can be found in the proprietary databases Thomson Reuters Integrity(SM) and Thomson Reuters Cortellis™. PMID:23462626

  19. Validation of cross-contamination control in biological safety cabinet for biotech/pharmaceutical manufacturing process.

    Science.gov (United States)

    Hu, Shih-Cheng; Shiue, Angus; Tu, Jin-Xin; Liu, Han-Yang; Chiu, Rong-Ben

    2015-12-01

    For class II, type A2 biological safety cabinets (BSC), NSF/ANSI Standard 49 should be conformed in cabinet airflow velocity derivation, particle contamination, and aerodynamic flow properties. However, there exists a potential problem. It has been built that the cabinet air flow stabilize is influenced by the quantity of downflow of air and the height above the cabinet exhaust opening. Three air downflow quantities were compared as an operating apparatus was placed from 20 to 40 cm above the bench of the cabinet. The results show that the BSC air downflow velocity is a function of increased sampling height, displaying that containment is improvingly permitted over product protection as the sampling height decreases. This study investigated the concentration gradient of particles at various heights and downflow air quantity from the bench of the BSC. Experiment results indicate that performance near the bench was better than in the rest of the BSC. In terms of height, the best cleanliness was measured at a height of 10 cm over the bench; it reduced actually with add in height. The empirical curves accommodate, founded on the concentration gradient of particle created was elaborated for evaluating the particle concentration at different heights and downflow air quantity from the source of the bench of the BSC. The particle image velocimetry system applied for BSC airflow research to fix amount of airflow patterns and air distribution measurement and results of measurements show how obstructions can greatly influence the airflow and contaminant transportation in a BSC. PMID:26257118

  20. How to produce male-only progeny in pest insects for SIT: a biotech approach.

    OpenAIRE

    Petrella, Valeria

    2014-01-01

    Insects represent the most abundant group of animals on earth, comprising about 800,000 described species, and approximately 10,000 of these species can be actually destructive for human activities. Pest control interventions, alternative to pesticides, are increasingly being implemented within the concept of Integrated Pest Management, involving the biological control to eradicate a pest from the area of interest. This concept has been recently extended also to those hemathoph...

  1. Who benefits from gm crops? Feeding the biotech giants, not the world's poor

    International Nuclear Information System (INIS)

    The biotechnology industry has aggressively touted GM as a solution to hunger and the global food crisis. Their arguments have been accepted by many politicians. This Friends of the Earth International (FoEI) report looks behind the spin and exposes the reasons why GM crops cannot, and are unlikely to ever, contribute to poverty reduction, global food security or sustainable farming (authors' abstract)

  2. Coaching' small biotech companies into success: the value-adding function of VC

    OpenAIRE

    Luukkonen, Terttu; Maunula, Mari

    2006-01-01

    The paper reports an empirical study on the non-financial value-added provided by Venture Capital investors to their investee firms. This study will use a four-class grouping of the various non-financial value-adding capabilities provided by VC firms, namely, scouting, monitoring, signalling and value-adding services. The study examines biotechnology industry in Finland. Finland has a dual system with independent (partially ever-green) VC companies and public or semi-public VC organisations. ...

  3. Scientific Advances with Aspergillus Species that Are Used for Food and Biotech Applications.

    Science.gov (United States)

    Biesebeke, Rob Te; Record, Erik

    2008-01-01

    Yeast and filamentous fungi have been used for centuries in diverse biotechnological processes. Fungal fermentation technology is traditionally used in relation to food production, such as for bread, beer, cheese, sake and soy sauce. Last century, the industrial application of yeast and filamentous fungi expanded rapidly, with excellent examples such as purified enzymes and secondary metabolites (e.g. antibiotics), which are used in a wide range of food as well as non-food industries. Research on protein and/or metabolite secretion by fungal species has focused on identifying bottlenecks in (post-) transcriptional regulation of protein production, metabolic rerouting, morphology and the transit of proteins through the secretion pathway. In past years, genome sequencing of some fungi (e.g. Aspergillus oryzae, Aspergillus niger) has been completed. The available genome sequences have enabled identification of genes and functionally important regions of the genome. This has directed research to focus on a post-genomics era in which transcriptomics, proteomics and metabolomics methodologies will help to explore the scientific relevance and industrial application of fungal genome sequences. PMID:21558706

  4. Market entry and exit by biotech and device companies funded by venture capital.

    Science.gov (United States)

    Burns, Lawton R; Housman, Michael G; Robinson, Charles A

    2009-01-01

    Start-up companies in the biotechnology and medical device sectors are important sources of health care innovation. This paper describes the role of venture capital in supporting these companies and charts the growth in venture capital financial support. The paper then uses longitudinal data to describe market entry and exit by these companies. Similar factors are associated with entry and exit in the two sectors. Entries and exits in one sector also appear to influence entry in the other. These findings have important implications for developing innovative technologies and ensuring competitive markets in the life sciences. PMID:19049998

  5. Biotech Approaches to Overcome the Limitations of Using Transgenic Plants in Organic Farming

    Directory of Open Access Journals (Sweden)

    Luca Lombardo

    2016-05-01

    Full Text Available Organic farming prohibits the use of genetically modified organisms (GMOs inasmuch as their genetic material has been altered in a way that does not occur naturally. In actual fact, there is a conventional identity between GMOs and transgenic organisms, so that genetic modification methods such as somatic hybridization and mutagenesis are equalized to conventional breeding. A loophole in this system is represented by more or less innovative genetic engineering approaches under regulatory discussion, such as cisgenesis, oligonucleotide-directed mutagenesis, and antisense technologies, that are redefining the concept of GMOs and might circumvent the requirements of the GMO legislation and, indirectly, of organic farming.

  6. Auswirkungen von Medikamentengenehmigungen auf die Bewertung von Biotech- und Pharmaunternehmen: Eine Ereignisstudie. Eine empirische Untersuchung

    OpenAIRE

    Sturm, Andreas

    2007-01-01

    Die Arbeit untersucht den Einfluss der Genehmigung von Medikamenten durch die amerikanische Zulassungsbehörde FDA (Food and Drug Administration) auf den Aktienkurs der Antrag stellenden Aktiengesellschaft. Dabei werden Genehmigungen von wichtigen pharmazeutischen und biopharmazeutischen Medikamenten aus den Jahren 1985-2004 herangezogen. Als Ergebnis kann festgehalten werden, dass die Aktienmärkte die neue Information in einer effizienten Art und Weise einarbeiten. Die Existenz eines Marktes ...

  7. Biotech Approaches to Overcome the Limitations of Using Transgenic Plants in Organic Farming

    OpenAIRE

    Luca Lombardo; Samanta Zelasco

    2016-01-01

    Organic farming prohibits the use of genetically modified organisms (GMOs) inasmuch as their genetic material has been altered in a way that does not occur naturally. In actual fact, there is a conventional identity between GMOs and transgenic organisms, so that genetic modification methods such as somatic hybridization and mutagenesis are equalized to conventional breeding. A loophole in this system is represented by more or less innovative genetic engineering approaches under regulatory dis...

  8. Biotech--Who Wins? Economic Benefits and Costs of Biotechnology Innovations in Agriculture

    OpenAIRE

    Moschini, GianCarlo

    2001-01-01

    The conceptual model necessary for an assessment of biotechnology's economic benefits and costs is outlined, emphasizing the need to account for the proprietary nature of biotechnology innovations. The model is illustrated with an application to Roundup Ready soybeans. The estimated value of this innovation is sizeable, with consumers and innovators claiming the largest shares of net benefits. Also, disparities in intellectual property rights protection across countries affect the distributio...

  9. Moira Yip. 2002. Tone (Cambridge Textbooks in Linguistics). Cambridge: Cambridge University Press. pp. xxxiv + 341.%声调音系学研究的重要进展——Moira Yip《声调》评介

    Institute of Scientific and Technical Information of China (English)

    范俊军; 宫齐

    2007-01-01

    Moira Yip上世纪80年代毕业于生成音系学发源地——麻省理工学院,获博士学位,是生成音系学创始人之一Morris Halle的门生。她对汉语方言情有独钟,早年博士论文《汉语声调音系学》(The Tonal Phonologv of Chinese)几乎涉及所有具代表性的汉语方言,后来又广泛涉猎非洲和美洲声调语言,将其声调研究成果全盘“优选论”化。

  10. Rezension zu: Jacqueline Broad, Karen Green: A History of Women’s Political Thought in Europe, 1400–1700. Cambridge: Cambridge University Press 2009.

    Directory of Open Access Journals (Sweden)

    Claudia Opitz-Belakhal

    2010-01-01

    Full Text Available Im vorliegenden Sammelband werden überwiegend bekannte Autorinnen der Frühen Neuzeit – wie Christine de Pizan, Marie de Gournay oder Mary Astell – aus einem neuen Blickwinkel, dem der politischen Ideengeschichte, präsentiert. Die europäische Perspektivierung, die der Buchtitel suggeriert, fehlt indes, denn es handelt sich fast ausschließlich um englische und französische Autorinnen. Auch die Frage, welche Vorzüge eine frauen- gegenüber einer geschlechtergeschichtlichen Blickrichtung hat, wird nur unbefriedigend beantwortet. Das Buch erscheint insofern bestenfalls als eine erste Einführung in ein weiterhin dringend zu bearbeitendes Feld.

  11. "Conclusión: la seguridad y la elección moral" en Security, Identity and Interest. A Sociology of International Relations, Cambridge University Press, Cambridge, 1999.

    OpenAIRE

    Bill MCSWEENEY

    2009-01-01

    El libro Security Identity and Interests: A Sociology of International Relations analiza el problema de la seguridad en relaciones internacionales y las lecturas que de este complejo y controvertido tema se han ofrecido desde la academia. El texto traducido es el capítulo final del libro, con el que Bill McSweeney profundiza en una explicación alternativa de la seguridad y del orden social a la que ofrece el neorrealismo, entre otras, proponiendo una “teoría reflexiva del orden social” que se...

  12. Raouf Ibrahim, Liquid Sloshing Dynamics: Theory and Applications , Cambridge University Press, Cambridge (2005) ISBN 0-521-83885-1 pp. xxi+948, £160, US$275, hbk.

    Science.gov (United States)

    Ohayon, Roger

    2008-08-01

    The appearance of this book is an event. Written by Professor Raouf Ibrahim, an internationally recognized expert in nonlinear vibrations and random responses of liquid-free surface and more generally liquid sloshing dynamics, this book is particularly welcome as it appears as a monumental monograph on various phenomena occurring in sloshing problems, mostly based on analytical results and discussions resulting from various particular tank geometries. As a consequence, this book will be a useful complement to computational mechanics studies of free surface sloshing effects-linear and nonlinear, periodic and random-in earthquake engineering, civil engineering (storage tanks), aerospace engineering (such as liquid propelled launchers), nuclear engineering, naval and offshore engineering, etc.

  13. El poder de la música en la vida cotidiana : DeNora, Tia (2000). Music in Everyday Life. Cambridge: Cambridge University Press.

    OpenAIRE

    Welschinger Lascano, Nicolás

    2011-01-01

    En su libro Music in Everyday Life, Tia DeNora parte de un señalamiento crucial: "demasiado a menudo, la música es considerada un estímulo capaz de trabajar independientemente de sus circunstancias de producción, distribución y consumo". En consecuencia, el libro propone derivar una teoría de los sentidos y efectos de la música etnográfica y pragmáticamente orientada, situada en un plano abiertamente sociológico, a través de explorar las distintas situaciones y modos en que esta es apropiada ...

  14. Jacqueline Broad, Karen Green: A History of Women’s Political Thought in Europe, 1400–1700. Cambridge: Cambridge University Press 2009.

    Directory of Open Access Journals (Sweden)

    Claudia Opitz-Belakhal

    2010-03-01

    Full Text Available Im vorliegenden Sammelband werden überwiegend bekannte Autorinnen der Frühen Neuzeit – wie Christine de Pizan, Marie de Gournay oder Mary Astell – aus einem neuen Blickwinkel, dem der politischen Ideengeschichte, präsentiert. Die europäische Perspektivierung, die der Buchtitel suggeriert, fehlt indes, denn es handelt sich fast ausschließlich um englische und französische Autorinnen. Auch die Frage, welche Vorzüge eine frauen- gegenüber einer geschlechtergeschichtlichen Blickrichtung hat, wird nur unbefriedigend beantwortet. Das Buch erscheint insofern bestenfalls als eine erste Einführung in ein weiterhin dringend zu bearbeitendes Feld.The collected volume at hand introduces mostly well-known authors from the early modern era – such as Christine de Pizan, Marie de Gournay, or Mary Astell – from the new perspective of the political history of ideas. The presentation of a European perspective suggested by the book’s title is, however, missing; the volume examines only English and French authors. The question as to which advantages are offered by the approach from the perspective of women’s and not gender history is answered only unsatisfactorily. Therefore, the book serves at best as an initial introduction to a field that needs further examination.

  15. Analisis Pengaruh Customer Experience Terhadap Loyalitas Merek Breadtalk (Studi Kasus Breadtalk Cambridge City Square Medan).

    OpenAIRE

    Brahmana, Hiskia Sembiring

    2012-01-01

    In the tight business competition, the company that only relies on figure and benefit can not be competed. Therefore, more of companies apply the concept of customer experience, i.e by add the experience ingredient in it’s product. BreadTalk is one of bakery company applies customer experience by the appearance of product that provide it’s cusomer with experiences by sense, feel, think, act, and relate to build the brand loyalty of consumer with creative experience. This research aims to s...

  16. Ingestion of phosphorus-32 at Massachusetts Institute of Technology, Cambridge, Massachusetts, identified on August 19, 1995

    International Nuclear Information System (INIS)

    On Monday, October 16, 1995, the Massachussetts Institue of Technology (MIT, the licensee) notified the US Nuclear Regulatory Commission (NRC) of an incident involving ingestion of phosphorus-32 by a researcher at the MIT Center for Cancer Research. The licensee informed the NRC that a researcher had reported the incident on August 19. The licensee initially estimated the intake as 500 microcuries (19 MBq) and the dose as 4000 millirem (40 mSv) to the individual. On October 12, the licensee informed the researcher that its final intake estimate was 579 microcuries (21 MBq), just under the 600 microcuries (22 MBq) which would represent an overexposure. On October 17, the NRC established an Incident Investigation Team to investigate the case. NRC also contracted with Lawrence Livermore National Laboratory and Oak Ridge Institute for Science and Education to do independent dose assessments of the urine sample data and the whole-body data. The Team concluded that the licensee's final intake and dose estimates were in accordance with accepted scientific references and NRC guidance. However, recognizing the uncertainties involved in the use of models to simulate human characteristics, the Team determined the intake would be better characterized as likely falling within a range of 500 to 750 microcuries (19--28 NMq). An NRC medical consultant concluded that no symptoms or acute effects should be observed from an intake of this level

  17. Using the Cambridge Structural Database to Teach Molecular Geometry Concepts in Organic Chemistry

    Science.gov (United States)

    Wackerly, Jay Wm.; Janowicz, Philip A.; Ritchey, Joshua A.; Caruso, Mary M.; Elliott, Erin L.; Moore, Jeffrey S.

    2009-01-01

    This article reports a set of two homework assignments that can be used in a second-year undergraduate organic chemistry class. These assignments were designed to help reinforce concepts of molecular geometry and to give students the opportunity to use a technological database and data mining to analyze experimentally determined chemical…

  18. Developing technology intelligence strategy to access knowledge of innovation clusters. : The case of KODAK in Cambridge

    OpenAIRE

    Dang, Rani Jeanne; Mortara, Letizia; Thomson, Ruth; Minshall, Tim

    2010-01-01

    International audience Current times are characterised by a knowledge-based economy and fast technological change. In this difficult environment, companies compete to maintain a relevant position through innovation. In response to these challenges, many companies are currently adopting an open approach to innovation, pursuing innovation by combining internal and external resources. Technology intelligence (TI) activities support the implementation of open innovation with the systematic cap...

  19. The Cambridge post-mastectomy radiotherapy (C-PMRT) index: A practical tool for patient selection

    International Nuclear Information System (INIS)

    Background and purpose: Post mastectomy radiotherapy (PMRT) reduces loco-regional recurrence (LRR) and has been associated with survival benefit. It is recommended for patients with T3/T4 tumours and/or ⩾4 positive lymph nodes (LN). The role of PMRT in 1–3 positive LN and LN negative patients is contentious. The C-PMRT index has been designed for selecting PMRT patients, using independent prognostic factors for LRR. This study reports a 10 year experience using this index. Materials and methods: The C-PMRT index was constructed using the following prognostic factors (a) number of positive LN/lymphovascular invasion, (b) tumour size (c) margin status and (d) tumour grade. Patients were categorised as high (H) risk, intermediate (I) risk and low (L) risk. PMRT was recommended for H and I risk patients. The LRR, distant metastasis and overall survival (OS) rates were measured from the day of mastectomy. Results: From 1999 to 2009, 898 invasive breast cancers in 883 patients were treated by mastectomy (H: 323, I: 231 and L: 344). At a median follow up of 5.2 years, 4.7% (42/898) developed LRR. The 5-year actuarial LRR rates were 6%, 2% and 2% for the H, I and L risk groups, respectively. 1.6% (14/898) developed isolated LRR (H risk n = 4, I risk group n = 0 and L risk n = 10). The 5-year actuarial overall survival rates were 67%, 77% and 90% for H, I and L risk groups, respectively. Conclusion: Based on published literature, one would have expected a higher LRR rate in the I risk group without adjuvant RT. We hypothesise that the I risk group LRR rates have been reduced to that of the L risk group by the addition of RT. Apart from LN status and tumour size, other prognostic factors should also be considered in selecting patients for PMRT. This pragmatic tool requires further validation

  20. Prevalence of eating disorders in three Cambridge general practices: hidden and conspicuous morbidity.

    OpenAIRE

    Whitehouse, A. M.; Cooper, P. J.; Vize, C V; Hill, C.; L. Vogel

    1992-01-01

    The aims of this study were to investigate the prevalence of anorexia nervosa, bulimia nervosa and partial syndromes in women general practice attenders to establish the relative proportions of 'conspicuous' and 'hidden' morbidity. A consecutive series of 540 women patients aged 16-35 years attending their family doctor were screened using a specially devised questionnaire, the weight and dietary practices survey. A total of 115 patients were selected for further assessment and of these 101 p...

  1. Statistical Mechanics of Disordered Systems - Series: Cambridge Series in Statistical and Probabilistic Mathematics (No. 18)

    Science.gov (United States)

    Bovier, Anton

    2006-06-01

    Our mathematical understanding of the statistical mechanics of disordered systems is going through a period of stunning progress. This self-contained book is a graduate-level introduction for mathematicians and for physicists interested in the mathematical foundations of the field, and can be used as a textbook for a two-semester course on mathematical statistical mechanics. It assumes only basic knowledge of classical physics and, on the mathematics side, a good working knowledge of graduate-level probability theory. The book starts with a concise introduction to statistical mechanics, proceeds to disordered lattice spin systems, and concludes with a presentation of the latest developments in the mathematical understanding of mean-field spin glass models. In particular, recent progress towards a rigorous understanding of the replica symmetry-breaking solutions of the Sherrington-Kirkpatrick spin glass models, due to Guerra, Aizenman-Sims-Starr and Talagrand, is reviewed in some detail. Comprehensive introduction to an active and fascinating area of research Clear exposition that builds to the state of the art in the mathematics of spin glasses Written by a well-known and active researcher in the field

  2. Linear Elastic Waves - Series: Cambridge Texts in Applied Mathematics (No. 26)

    Science.gov (United States)

    Harris, John G.

    2001-10-01

    Wave propagation and scattering are among the most fundamental processes that we use to comprehend the world around us. While these processes are often very complex, one way to begin to understand them is to study wave propagation in the linear approximation. This is a book describing such propagation using, as a context, the equations of elasticity. Two unifying themes are used. The first is that an understanding of plane wave interactions is fundamental to understanding more complex wave interactions. The second is that waves are best understood in an asymptotic approximation where they are free of the complications of their excitation and are governed primarily by their propagation environments. The topics covered include reflection, refraction, the propagation of interfacial waves, integral representations, radiation and diffraction, and propagation in closed and open waveguides. Linear Elastic Waves is an advanced level textbook directed at applied mathematicians, seismologists, and engineers. Aimed at beginning graduate students Includes examples and exercises Has application in a wide range of disciplines

  3. Dogancan Özsel (ed. Reflections on Conservatism (Newcastle: Cambridge Scholars Publishing, 2011

    Directory of Open Access Journals (Sweden)

    Garrett Barden

    2012-03-01

    Full Text Available In the foreword to his The Ancien Régime and the Revolution (1856 Alexis de Tocqueville wrote that “No nation had ever before embarked on so resolute an attempt as that of the French in 1789 to break with the past, to make, as it were, a scission in their life line and to create an unbridgeable gulf between all they had hitherto been and all they now aspired to be. ...in a word, they spared no pains in their endeavour to obliterate their former selves.”

  4. Philosophy at Cambridge, Newsletter of the Faculty of Philosophy, Issue 10

    OpenAIRE

    Lecky-Thompson, Jenni

    2013-01-01

    Newsletter of the Philosophy Faculty. Articles by: Tim Crane, 'From the Chair' ; Huw Price, "Erroneously supposed to do no harm"; Arthur Gibson, 'The Wittgenstein-Skinner Archive; Emily Thomas, 'Elizabeth Anscombe'.

  5. Herman Paul. (2011. Hayden White: The Historical Imagination. Cambridge: Polity Press [204 pp.

    Directory of Open Access Journals (Sweden)

    Ariel C. Lopez

    2011-12-01

    Full Text Available Ang akdang ito ni Herman Paul ay isang kritikal na pagsasakasaysayan(historicization ng mga ideya ni Hayden White na maibibilang sapinakamahahalagang pilosopo ng kasaysayan ng kontemporaryong panahon.Si White ay tanyag bilang simbolo par excellence ng postmodernistang kasaysayan na reaksyon laban sa noo’y, at hanggang ngayo’y, namamayaning positibistang pananaw (na inuugat sa Alemang historyador ng ika-19 na dantaon na si Leopold von Ranke. Noong Dekada ’50 pa lang, masusulyapan na ang pagsalungat ni White sa tradisyong positibista nang tawagin niya si Ranke bilang “kawawang nilalang na nagkandabulag sa paghahanap ng ‘kung ano ang tunay na nangyari’”(Paul, 2011, p.105. Para kay White, ang nakaraan per se (bilang nakaraan ay isang “walang-kahulugang katotohanan” (meaningless reality lamang. Binibigyang kahulugan ng mga historyador ang nakaraan sa pamamagitan ng mga naratibo na siyang humuhugis at nagtatakda sa kahulugan. Sa magnum opus ni White na pinamagatang Metahistory: The Historical Imagination in Nineteenth-Century Europe (1973, inilalatag niya ang ibat-ibang pagbabanghay (emplotment at tropos (tropesna implisitong sinusundan at sinasandigan ng mga (positibistang historyador upang magkaroon ng makatotohanang naratibo.

  6. Chemistry of fossil fuels and biofuels (cambridge series in chemical engineering)

    CERN Document Server

    Schobert, Harold

    2013-01-01

    Focusing on today's major fuel resources - ethanol, biodiesel, wood, natural gas, petroleum products and coal - this book discusses the formation, composition and properties of the fuels, and the ways in which they are processed for commercial use. The book examines the origin of fuels through natural processes such as photosynthesis and the geological transformation of ancient plant material; the relationships between their composition, molecular structures, and physical properties; and the various processes by which they are converted or refined into the fuel products appearing on today's market. Fundamental chemical aspects such as catalysis and the behaviour of reactive intermediates are presented, and global warming and anthropogenic carbon dioxide emissions are also discussed. The book is suitable for graduate students in energy engineering, chemical engineering, mechanical engineering and chemistry, as well as professional scientists and engineers.

  7. THE USE OF PRIMARY SOURCE MATERIAL IN ACADEMIC RESEARCH: A VIEW FROM CAMBRIDGE ARCHIVE EDITIONS

    OpenAIRE

    Jessica Lagan

    2015-01-01

    The article analyses the possibility of using historical sources (and above all primary sources) in political science research. Particularly, the author provides specific examples of archive documents to prove the thesis that history is grounded in politics and governance. 

  8. Residencia del colegio de Cristo, en Cambridge - Gran Bretaña

    Directory of Open Access Journals (Sweden)

    Denys Lasdun & Partners, Arquitectos

    1973-03-01

    Full Text Available This structure rises by successive terraces, extending from within the existing college onto King's Street but keeping the traditional tone of university isolation from the rest of the city. The main floor contains utility rooms, shops, porter's lodging, sitting rooms, lecture halls, conference rooms, bar, and parking access. The upper floors house the living quarters, i.e. rooms with bath. A reinforced concrete base supports the upper, prefabricated floors.El edificio se levanta —por medio de terrazas sucesivas— desde el colegio existente hasta volar sobre la calle King, recogiendo el tradicional concepto de apertura hacia dentro y aislamiento respecto de la ciudad. La planta baja alberga: - las zonas de instalaciones; - tiendas; - vivienda del conserje; - estancias nobles, tales como salas de lectura, coloquios y bar; - acceso al aparcamiento. En las plantas altas están situadas las habitaciones con baño. La estructura de la planta baja es de hormigón armado y soporta las plantas elevadas, construidas a base de elementos prefabricados.

  9. 给你的Zen安个家——Cambridge Soundworks Zen底座

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    不知道是不是iPod卖得太好了,现在有越来越多的厂商开始为iPod制作播放底座。也许你已经注意到了JVC推出的几款产品,现在创新也有一款相似的产品面世了,不过它支持的却是自己的Zen播放器。如果你是一个Zen的忠实用户,并对Creative的产品抱有信心,这款产品应该是一个不错的选择。

  10. Cambridge academic English: an integrated skills course for EAP - B2 upper intermediate

    OpenAIRE

    Simpson, Adam John

    2012-01-01

    For those who have had the experience of preparing students for academic study using a general English course book, the notion of a series that progressively aims to develop the kinds of skills necessary for tertiary study in an English-medium institution should be immediately compelling. With a market existing for a series, Cambridge’s three-level (B1+ to C1) integrated skills course for higher education students at university or on foundation courses has an audience ready and waiting for bo...

  11. An Evaluation on Coursebook (Cambridge English for the Media):A Case Study

    Institute of Scientific and Technical Information of China (English)

    赖燕容

    2013-01-01

      Coursebook is an essential part in English language teaching. Evaluating a coursebook is very helpful task for teachers’ development. This paper reviews three methods of evaluating coursebook, which are the impressionistic method, the checklist meth⁃od, and the in-depth method. Then the author adopts the hybrid of these three methods mentioned to evaluate a coursebook-Cam⁃bridge English for the Media-used by some Chinese students in a one-year exchange programme in UK. Questionnaire and semi-structured interviews are carried out with the students to get their views about the coursebook. At the end, this paper compares teacher’s view with the learners’based on the data from the questionnaire and semi-structured interviews. The results of this study show that there are conflicts between the teacher’s views and the students’on the coursebook.

  12. R&D and knowledge dynamics in university-industry relationships in biotech and pharmaceuticals: An agent-based model

    OpenAIRE

    Triulzi, Giorgio; Scholz, Ramon; Pyka, Andreas

    2011-01-01

    In the last two decades, University-Industry Relationships have played an outstanding role in shaping innovation activities in Biotechnology and Pharmaceuticals. Despite the growing importance and the considerable scope of these relationships, there still is an intensive and open debate on their short and long term effects on the research system in life sciences. So far, the extensive literature on this topic has not been able to provide a widely accepted answer. This work introduces a new wa...

  13. Electrochemical sensor for multiplex screening of genetically modified DNA: identification of biotech crops by logic-based biomolecular analysis.

    Science.gov (United States)

    Liao, Wei-Ching; Chuang, Min-Chieh; Ho, Ja-An Annie

    2013-12-15

    Genetically modified (GM) technique, one of the modern biomolecular engineering technologies, has been deemed as profitable strategy to fight against global starvation. Yet rapid and reliable analytical method is deficient to evaluate the quality and potential risk of such resulting GM products. We herein present a biomolecular analytical system constructed with distinct biochemical activities to expedite the computational detection of genetically modified organisms (GMOs). The computational mechanism provides an alternative to the complex procedures commonly involved in the screening of GMOs. Given that the bioanalytical system is capable of processing promoter, coding and species genes, affirmative interpretations succeed to identify specified GM event in terms of both electrochemical and optical fashions. The biomolecular computational assay exhibits detection capability of genetically modified DNA below sub-nanomolar level and is found interference-free by abundant coexistence of non-GM DNA. This bioanalytical system, furthermore, sophisticates in array fashion operating multiplex screening against variable GM events. Such a biomolecular computational assay and biosensor holds great promise for rapid, cost-effective, and high-fidelity screening of GMO. PMID:23893064

  14. Analytical criteria for performance characteristics of IgE binding methods for evaluating safety of biotech food products.

    Science.gov (United States)

    Holzhauser, Thomas; Ree, Ronald van; Poulsen, Lars K; Bannon, Gary A

    2008-10-01

    There is detailed guidance on how to perform bioinformatic analyses and enzymatic degradation studies for genetically modified crops under consideration for approval by regulatory agencies; however, there is no consensus in the scientific community on the details of how to perform IgE serum studies. IgE serum studies are an important safety component to acceptance of genetically modified crops when the introduced protein is novel, the introduced protein is similar to known allergens, or the crop is allergenic. In this manuscript, we describe the characteristics of the reagents, validation of assay performance, and data analysis necessary to optimize the information obtained from serum testing of novel proteins and genetically modified (GM) crops and to make results more accurate and comparable between different investigations. PMID:18727951

  15. The value of trust in biotech crop development: a case study of Bt cotton in Burkina Faso

    Directory of Open Access Journals (Sweden)

    Ezezika Obidimma C

    2012-11-01

    Full Text Available Abstract Background Agricultural biotechnology public-private partnerships (PPPs have been recognized as having great potential in improving agricultural productivity and increasing food production in sub-Saharan Africa. However, there is much public skepticism about the use of GM (genetically modified crops and suspicion about private sector involvement in agbiotech projects. This case study sought to understand the role of trust in the Bacillus thuringiensis (Bt cotton in Burkina Faso project by exploring practices and challenges associated with trust-building, and determining what makes these practices effective from the perspective of multiple stakeholders. Methods We conducted semi-structured, face-to-face interviews to obtain stakeholders’ understanding of trust in general as well as in the context of agbiotech PPPs. Relevant documents and articles were analyzed to generate descriptions of how trust was operationalized in this evolving agbiotech PPP. Data was analyzed based on emergent themes to create a comprehensive narrative on how trust is understood and built among the partners and with the community. Results We derived four key lessons from our findings. First, strong collaboration between research, industry and farmers greatly contributes to both the success of, and fostering of trust in, the partnership. Second, this case study also revealed the important, though often unrecognized, role of researchers as players in the communication strategy of the project. Third, effective and comprehensive communication takes into account issues such as illiteracy and diversity. Fourth, follow-up at the field level and the need for a multifaceted communications strategy is important for helping push the project forward. Conclusions Burkina Faso’s well-established and effective cotton selling system laid the foundation for the implementation of the Bt cotton project – particularly, the strong dialogue and the receptivity to collaboration. Interviewees reported that establishing and maintaining trust among partners, researchers and the community in Burkina Faso greatly contributed to the success of the PPP. By addressing challenges to building trust and engaging in trust-building practices early on, improvements in the effectiveness of agbiotech PPPs are likely.

  16. Competiveness and Innovation in High-tech Companies: an Application to the Italian Biotech and Aerospace Industries

    OpenAIRE

    Armando Calabrese; Domenico Campisi; Guendalina Capece; Roberta Costa; Francesca Di Pillo

    2013-01-01

    Innovation activities are a critical factor in national and regional development. The innovative behaviour of companies is one of the main sources of competitiveness, business survival, economic growth and employment in a territory. It is therefore important to identify and understand the factors that determine innovation behaviour among enterprises. In line with this, the aim of this study is to analyse the relations between innovation‐related variables and the impact that they have on compa...

  17. Teaching and implementing autonomous robotic lab walkthroughs in a biotech laboratory through model-based visual tracking

    Science.gov (United States)

    Wojtczyk, Martin; Panin, Giorgio; Röder, Thorsten; Lenz, Claus; Nair, Suraj; Heidemann, Rüdiger; Goudar, Chetan; Knoll, Alois

    2010-01-01

    After utilizing robots for more than 30 years for classic industrial automation applications, service robots form a constantly increasing market, although the big breakthrough is still awaited. Our approach to service robots was driven by the idea of supporting lab personnel in a biotechnology laboratory. After initial development in Germany, a mobile robot platform extended with an industrial manipulator and the necessary sensors for indoor localization and object manipulation, has been shipped to Bayer HealthCare in Berkeley, CA, USA, a global player in the sector of biopharmaceutical products, located in the San Francisco bay area. The determined goal of the mobile manipulator is to support the off-shift staff to carry out completely autonomous or guided, remote controlled lab walkthroughs, which we implement utilizing a recent development of our computer vision group: OpenTL - an integrated framework for model-based visual tracking.

  18. Build your own lab: Do-it-yourself biology and the rise of citizen biotech-economies

    OpenAIRE

    Meyer, Morgan

    2012-01-01

    Most articles on garage biology and do-it-yourself (DIY) biology highlight its somewhat immaterial cultures or ideologies. The issues usually raised include: the ways in which do-it-yourself biology potentially democratizes science and fosters a citizen science, that its practitioners are a "creative proof of the hacker principle", that the field is an illustration of the open source movement, that concerns about control, security and safety need to be addressed. However, rather than focusing...

  19. BOOK REVIEW: Structures in the Universe by Exact Methods: Formation, Evolutions, Interactions (Cambridge Monographs on Mathematical Physics) Structures in the Universe by Exact Methods: Formation, Evolutions, Interactions (Cambridge Monographs on Mathematical Physics)

    Science.gov (United States)

    Coley, Alan

    2010-05-01

    In this book the use of inhomogeneous models in cosmology, both in modelling structure formation and interpreting cosmological observations, is discussed. The authors concentrate on exact solutions, and particularly the Lemaitre-Tolman (LT) and Szekeres models (the important topic of averaging is not discussed). The book serves to demonstrate that inhomogeneous metrics can generate realistic models of cosmic structure formation and nonlinear evolution and shows that general relativity has a lot more to offer to cosmology than just the standard spatially homogeneous FLRW model. I would recommend this book to people working in theoretical cosmology. In the introduction (and in the concluding chapter and throughout the book) a reasonable discussion of the potential problems with the standard FLRW cosmology is presented, and a list of examples illustrating the limitations of standard FLRW cosmology are discussed (including potential problems with perturbation methods). In particular, the authors argue that the assumptions of isotropy and spatial homogeneity (and consequently the Copernican principle) must be properly challenged and revisited. Indeed, it is possible for `good old general relativity' to be used to explain cosmological observations without introducing speculative elements. In part I of the book the necessary background is presented (readers need a background in general relativity theory at an advanced undergraduate or graduate level). There is a good (and easy to read) review of the exact spherically symmetric dust Lemaitre-Tolman model (LT) (often denoted the LTB model) and the Lemaitre and Szekeres models. Light propogation (i.e. null geodesics, for both central and off-center observers) in exact inhomogeneous (LT) models is reviewed. In part II a number of applications of exact inhomogeneous models are presented (taken mainly from the authors' own work). In chapter 4, the evolution of exact inhomogeneous models (primarily the LT model, but also the Szekeres model) is studied regarding structure formation. I thought that the authors describe the advantages and drawbacks of the idealized exact solutions used in the physical modelling in a reasonable manner (although more concise conclusions might have been useful). The authors also address the formation of a galaxy with a central black hole, the formation and evolution of rich galactic clusters and voids and other structures, and the effects of radiation in the models. The most interesting application is presented in chapter 5; namely, the effects of inhomogeneities on observations such as the luminosity distance relation and the explanation of the observed dimming of distant SN Ia (which is usually interpreted within the standard FLRW model in terms of the existence of dark energy). The main conclusion of this work is that data can be reproduced within the LT model (via inhomogeneities in general relativity, but without introducing dark energy). In particular, a number of exact LT solutions were surveyed, and a full discussion of various models in the literature (and a critique of the various assumptions) is presented. In the next chapter the possible resolution of the horizon problem without inflation, in terms of shell crossing in a LT model, is discussed. This is perhaps the most controversial chapter of the book. In the final chapter 7, the influence of inhomogeneous structures in the path of a light ray (for both center and off-center observers in a special Szekeres Swiss cheese model) on the observed temperature distribution of the CMB is discussed. This is a very important topic, but only a heuristic and qualitative study is presented here; more work on the multipole moments of higher order would be necessary for a more comprehensive analysis.

  20. Christopher Clark et Wolfram Kaiser (eds), Culture Wars. Secular-Catholic Conflicts in Nineteenth-Century Europe, Cambridge, Cambridge University Press, 2003, 368 p. ISBN: 0521793130. 50 livres sterling.

    OpenAIRE

    Pilbeam, Pamela

    2006-01-01

    Les « guerres culturelles », dont traite cet ouvrage collectif, opposait principalement les catholiques ultramontains et conservateurs aux libéraux, et étaient menées avec la plume comme arme. Dans une certaine mesure, ces affrontements font écho aux luttes entre le pape et les nations européennes. Toutefois, selon les auteurs, les forces motrices de ces querelles sont souvent à rechercher dans des conflits plus locaux. Dans leur introduction, Christopher Clark et Wolfgang Kaiser précisent la...

  1. Rezension zu: Nicole C. Karafyllis, Gotling Ulshöfer: Sexualized Brains. Cambridge u.a.: MIT Press 2008

    Directory of Open Access Journals (Sweden)

    Sigrid Schmitz

    2009-07-01

    Full Text Available In der Auseinandersetzung um geschlechtliche Normierungen spielt die moderne Hirnforschung eine wirkmächtige und inzwischen disziplinenübergreifende Rolle. Nicole Karafyllis und Gotlind Ulshöfer stellen in diesem Sammelband mit Beiträgen aus Neurowissenschaft, Psychologie, Soziologie, Kulturwissenschaft und Philosophie ein multiperspektivisches Diskursfeld zu der Frage vor, ob die Emotionale Intelligenz (EI als erstrebenswerte Fähigkeit die klassische Kodierung in männliche Rationalität bzw. weibliche Emotionalität dekonstruieren und ein emanzipatorisches Potential entgegen gesellschaftlichen Hierarchisierungen entfalten kann. Viele Aspekte, Verbindungen zwischen den Diskurssträngen und wechselseitige Beeinflussungen, aber auch disziplinäre Eingrenzungen werden sichtbar, die eine kritische Fortführung des hier angestoßenen Dialogs notwendig machen.

  2. Book Review, Ethics and the Media: An Introduction, by Stephen J. A. Ward (Cambridge U Press, 2011)

    DEFF Research Database (Denmark)

    Ess, Charles

    2013-01-01

    I highlight important elements of the volume, its context in digital ethics more broadly, and contributions to both journalism ethics as such and digital ethics as an emerging field.......I highlight important elements of the volume, its context in digital ethics more broadly, and contributions to both journalism ethics as such and digital ethics as an emerging field....

  3. DATA SONIFICATION, FROM PHYSICS TO HEALTH - Interview to Domenico Vicinanza and Genevieve Williams, Anglia Ruskin University, Cambridge.

    CERN Document Server

    2016-01-01

    In this interview, recorded during the 2016 ICTR-PHE conference organized by CERN in Geneva at the International Conference Centre (CICG) in February, Dr. Domenico Vicinanza and Genevieve Williams describe the use of music and sound as tools for scientific investigation, with specific reference to biomedical sciences and show sonifications in action in a practical demonstration carried pout on physicist musician Chiara Mariotti.

  4. The contribution of media analysis to the evaluation of environmental interventions: the commuting and health in Cambridge study

    OpenAIRE

    Kesten, JM; Cohn, S; Ogilvie, D.

    2014-01-01

    Background: Media content can increase awareness of, and shape interactions with, public health interventions. As part of a natural experimental evaluation of the travel, physical activity and health impacts of the Cambridgeshire Guided Busway, we analysed print and social media discourse and interview data to understand the nature of new transport infrastructure and how it was experienced. Methods: Newspaper articles were systematically retrieved from the LexisNexis database and tweets w...

  5. Regional collective learning processes, innovation and growth of high technology SMEs: The case of the Cambridge region

    OpenAIRE

    Keeble, David; Lawson, Clive; Moore, Barry; Wilkinson, Frank

    1998-01-01

    Recent theoretical research on the technological development of dynamic European regions has drawn attention to the supposedly key role of "untraded interdependencies" between local firms and other organisations (Storper, 1995), involving informal inter-firm networking (Yeung, 1994) and processes of "collective learning" (Camagni, 1991, Lorenz, 1992). These processes, which involve exchange and development of technological expertise, are seen as being based on relationships of trust and recip...

  6. Effect of income inequality on quality of tertiary education: Should professors from Cambridge thank to Robin Hood?

    OpenAIRE

    Jedlička, Roman

    2013-01-01

    Many factors influence quality of higher education. Current research mostly works with economic factors (GDP, higher education expenditures etc.). However, there are also publications that examine an impact of sociological aspects on quality of higher education. My research examined the impact of income inequality on quality of tertiary education. In the analysis of socioeconomic data of 76 countries I have proven that there is no linear relationship between income inequality and quality of t...

  7. EU External Relations Law: Text, Cases and Materials, Bart Van Vooren and Ramses A. Wessel, Cambridge University Press, UK, 2014

    DEFF Research Database (Denmark)

    Butler, Graham

    2014-01-01

    This latest textbook contributing to the field of EU external relations law is unique in that it is the first such book in the post-Treaty of Lisbon environment to take a wide-angled look on as many aspects of the growing area as it continues to develop within the legal parameters as set by the...... Treaties, and it is suitably placed to become the core text for teaching this expanding EU policy field. In their book, EU External Relations Law: Text, Cases and Materials, Van Vooren and Wessel seek to fill the gap in up-to-date literature from a legal standpoint in the field of external relations of the...

  8. Sensor fusion: Spatial reasoning and scene interpretation; Proceedings of the Meeting, Cambridge, MA, Nov. 7-9, 1988

    Science.gov (United States)

    Schenker, Paul S. (Editor)

    1989-01-01

    The present conference discusses topics in the fusion of active and passive sensors, object estimation and verification, three-dimensional representation and knowledge integration, three-dimensional perception from multisensor data, the representation of uncertainty in multisensor fusion, and sensor calibration and registration. Also discussed are the areas of multisensor target detection and classification, multisensor processing architectures, knowledge structures and spatial reasoning, sensory interfaces to telerobotic systems, and navigation with spatial data bases.

  9. Sweig E. Julia, Inside The Cuban Revolution, Cambridge, Massachusetts, London, England, Harvard University Press, 2002, 254 p.

    OpenAIRE

    Burgos, Elizabeth

    2005-01-01

    Sin duda se trata de un hito en la historiografía de la revolución cubana. Primeramente por tratarse de la primera investigación rigurosa sobre el periodo previo a la revolución, y por que la autora - y en ello se debe poner  énfasis -, contó con el raro privilegio de consultar los archivos oficiales cubanos, lo que le agrega a la calidad académica que de por sí ya tiene la obra, un  valor adicional. Disponer de fuentes de primera mano, - cartas, documentos emitidos por los diferentes actores...

  10. Book Review - Water Resource Economics (MIT Press, Cambridge, 2006, 402 pages (hardback), ISBN 0-262-07267-X)

    OpenAIRE

    Robinson, Jackie

    2008-01-01

    As developed countries reach a state where decisions regarding the supply and distribution of water resources are made in an environment of a ‘mature water economy’, water managers are increasingly turning towards economics to assist them to plan future supply to meet increasing demand. Griffin approaches the management of water resources from a neoclassical economics perspective. In short, economic efficiency and competitive markets dominate the rationale for resource management. Griffin has...

  11. Fiber optic and laser sensors IV; Proceedings of the Meeting, Cambridge, MA, Sept. 22-24, 1986

    Science.gov (United States)

    De Paula, Ramon P. (Editor); Udd, Eric (Editor)

    1987-01-01

    The conference presents papers on industrial uses of fiber optic sensors, point and distributed polarimetric optical fiber sensors, fiber optic electric field sensor technology, micromachined resonant structures, single-mode fibers for sensing applications, and measurement techniques for magnetic field gradient detection. Consideration is also given to electric field meter and temperature measurement techniques for the power industry, the calibration of high-temperature fiber-optic microbend pressure transducers, and interferometric sensors for dc measurands. Other topics include the recognition of colors and collision avoidance in robotics using optical fiber sensors, the loss compensation of intensity-modulating fiber-optic sensors, and an embedded optical fiber strain tensor for composite structure applications.

  12. Nicole C. Karafyllis, Gotling Ulshöfer: Sexualized Brains. Cambridge u.a.: MIT Press 2008

    OpenAIRE

    Sigrid Schmitz

    2009-01-01

    In der Auseinandersetzung um geschlechtliche Normierungen spielt die moderne Hirnforschung eine wirkmächtige und inzwischen disziplinenübergreifende Rolle. Nicole Karafyllis und Gotlind Ulshöfer stellen in diesem Sammelband mit Beiträgen aus Neurowissenschaft, Psychologie, Soziologie, Kulturwissenschaft und Philosophie ein multiperspektivisches Diskursfeld zu der Frage vor, ob die Emotionale Intelligenz (EI) als erstrebenswerte Fähigkeit die klassische Kodierung in männliche Rationalität bzw....

  13. Rezension zu: Nicole C. Karafyllis, Gotling Ulshöfer: Sexualized Brains. Cambridge u.a.: MIT Press 2008

    OpenAIRE

    Sigrid Schmitz

    2009-01-01

    In der Auseinandersetzung um geschlechtliche Normierungen spielt die moderne Hirnforschung eine wirkmächtige und inzwischen disziplinenübergreifende Rolle. Nicole Karafyllis und Gotlind Ulshöfer stellen in diesem Sammelband mit Beiträgen aus Neurowissenschaft, Psychologie, Soziologie, Kulturwissenschaft und Philosophie ein multiperspektivisches Diskursfeld zu der Frage vor, ob die Emotionale Intelligenz (EI) als erstrebenswerte F...

  14. Nicole C. Karafyllis, Gotling Ulshöfer: Sexualized Brains. Cambridge u.a.: MIT Press 2008

    Directory of Open Access Journals (Sweden)

    Sigrid Schmitz

    2009-07-01

    Full Text Available In der Auseinandersetzung um geschlechtliche Normierungen spielt die moderne Hirnforschung eine wirkmächtige und inzwischen disziplinenübergreifende Rolle. Nicole Karafyllis und Gotlind Ulshöfer stellen in diesem Sammelband mit Beiträgen aus Neurowissenschaft, Psychologie, Soziologie, Kulturwissenschaft und Philosophie ein multiperspektivisches Diskursfeld zu der Frage vor, ob die Emotionale Intelligenz (EI als erstrebenswerte Fähigkeit die klassische Kodierung in männliche Rationalität bzw. weibliche Emotionalität dekonstruieren und ein emanzipatorisches Potential entgegen gesellschaftlichen Hierarchisierungen entfalten kann. Viele Aspekte, Verbindungen zwischen den Diskurssträngen und wechselseitige Beeinflussungen, aber auch disziplinäre Eingrenzungen werden sichtbar, die eine kritische Fortführung des hier angestoßenen Dialogs notwendig machen.Modern brain research plays a powerful and by now cross-disciplinary role in the debates on gender normalization. Nicole Karafylis and Gotlind Ulshöfer present the field of discourse from diverse perspectives, including contributions from neuroscience, psychology, sociology, cultural studies, and philosophy. They question whether Emotional Intelligence (EI as a desirable ability can deconstruct the classic encoding of masculine rationality and feminine emotionality and can therefore have emancipatory potential by opposing the hierarchy of society. The authors uncover and define many aspects such as connections between strands of discourses, mutual influences, and the limits of disciplines. These aspects show that the dialogue begun here must be critically continued.

  15. Welfare, growth and environment: a sceptical review of the skeptical environmentalist (Bjørn Lomborg, Cambridge University Press, 2001)

    OpenAIRE

    FitzRoy, Felix R.; Ian Smith

    2002-01-01

    Previously in the University eprints HAIRST pilot service at http://eprints.st-andrews.ac.uk/archive/00000052/ March 2002. Forthcoming as a review article in the Scottish Journal of Political Economy In his wide ranging attempt to review the literature on economic development and welfare in relation to the environment, Lomborg claims balance and objectivity, but actually presents a thoroughly misleading picture of environmental prospects and research, global economic developmen...

  16. We cruised through a terrible storm: A Critical Evaluation of Vocabulary in Use: Intermediate (Cambridge University Press).

    OpenAIRE

    Ian, Munby

    2004-01-01

    This paper begins with a background to Vocabulary In Use Intermediate and an overview of the importance and treatment of vocabulary in the recent history of language learning. In Part One, the approach underlying the treatment, selection, organization and presentation of vocabulary in the book is discussed. In Part Two, the text is evaluated in the light of what is known about vocabulary acquisition and approaches to vocabulary acquisition, with particular emphasis on the role of memory, stra...

  17. Commuting and health in Cambridge: a study of a 'natural experiment' in the provision of new transport infrastructure

    OpenAIRE

    Cohn Simon; Jones Natalia; Panter Jenna; Mackett Roger; Guell Cornelia; Jones Andy; Griffin Simon; Ogilvie David; Yang Lin; Chapman Cheryl

    2010-01-01

    Abstract Background Modifying transport infrastructure to support active travel (walking and cycling) could help to increase population levels of physical activity. However, there is limited evidence for the effects of interventions in this field, and to the best of our knowledge no study has convincingly demonstrated an increase in physical activity directly attributable to this type of intervention. We have therefore taken the opportunity presented by a 'natural experiment' in Cambridgeshir...

  18. Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: Results from the Cambridge Breast IMRT trial

    International Nuclear Information System (INIS)

    Background: The use of intensity-modulated radiotherapy (IMRT) in breast cancer reduces clinician-assessed breast tissue toxicity including fibrosis, telangectasia and sub-optimal cosmesis. Patient reported outcome measures (PROMs) are also important as they provide the patient’s perspective. This longitudinal study reports on (a) the effect of forward planned field-in-field IMRT (∼simple IMRT) on PROMs compared to standard RT at 5 years after RT, (b) factors affecting PROMs at 5 years after RT and (c) the trend of PROMs over 5 years of follow up. Methods: PROMs were assessed at baseline (pre-RT), 6, 24 and 60 months after completion of RT using global health (EORTC QLQ C30) and 4 breast symptom questions (BR23). Also, 4 breast RT-specific questions were included at 6, 24 and 60 months: change in skin appearance, firmness to touch, reduction in breast size and overall change in breast appearance since RT. The benefits of simple IMRT over standard RT at 5 years after RT were assessed using standard t-test for global health and logistic regression analysis for breast symptom questions and breast RT-specific questions. Clinical factors affecting PROMs at 5 years were investigated using a multivariate analysis. A repeated mixed model was applied to explore the trend over time for each of PROMs. Results: (89%) 727/815, 84%, 81% and 61% patients completed questionnaires at baseline, 6, 24 and 60 months respectively. Patients reported worse toxicity for all four BR23 breast symptoms at 6 months, which then improved over time (p < 0.0001). They also reported improvement in skin appearance and breast hardness over time (p < 0.0001), with no significant change for breast shrinkage (p = 0.47) and overall breast appearance (p = 0.13). At 5 years, PROMs assessments did not demonstrate a benefit for simple IMRT over standard radiotherapy. Large breast volume, young age, baseline surgical cosmesis and post-operative infection were the most important variables to affect PROMs. Conclusions: This study was unable to demonstrate the benefits of IMRT on PROMs at 5 years. PROMs are influenced by non-radiotherapy factors and surgical factors should be optimised to improve patients’ outcome. Only a small proportion of patients report moderate–severe breast changes post radiotherapy, with most PROMs improving over time. The difference in clinician assessment and PROMs outcome requires further investigation

  19. A multi-modal approach to dementia prevention: A Report from the Institute of Public Health Cambridge

    OpenAIRE

    CFAS MRC; Olanrewaju, Olawale; Brayne, Carol; Clare, Linda; Barnes, Linda

    2015-01-01

    Background: Globally, dementia is the most frequent form of degenerative condition in the older adult population and poses a major health burden with high socioeconomic costs (1). So far, attempts to find pharmacological interventions that can change the onset or progression of dementia have been largely unsuccessful, prompting a shift to focus on interventions aimed at modifying risk factors that occur throughout the life course (2-5). Methods: The Cognitive Function and Ageing Stu...

  20. Emotional Development: The Organization of Emotional Life in the Early Years. Cambridge Studies in Social and Educational Development.

    Science.gov (United States)

    Sroufe, L. Alan

    Written for researchers and clinicians, this book integrates key perspectives in order to illuminate common beliefs about core processes of emotional development. The book is divided into three parts. Part 1 discusses the nature of emotional development. Topics covered here include: (1) questions relevant in a developmental assessment of emotions;…

  1. Reinterpreting Islamic Historiography: Hārūn al-Rashīd and the Narrative of the ‘Abbāsid Caliphate, Cambridge Studies in Islamic Civilisation, Cambridge, Cambridge University Press, 1999, x-236 p., table généalogique, index.

    OpenAIRE

    Szuppe, Maria

    2010-01-01

    Le regain d’intérêt pour l’historiographie de l’époque islamique peut-être situé dans le cadre des nouvelles approches pour l’étude de l’histoire des sociétés musulmanes, approches pluridisciplinaires mettant à profit des données nouvelles (archéologiques, numismati­ques ...), et les nouvelles interprétations des sources connues. L’ouvrage de T. el-Hibri se situe dans ce même courant auquel appartiennent aussi le livre de J. Scott Meisami, Persian Historiography to the End of the Twelth Centu...

  2. Religious Experience and Lay Society in T’ang China: A Reading of Tai Fu’s Kuang-i chi, by Glen Dudbridge. Cambridge Studies in Chinese History, Literature and Institutions. Cambridge: Cambridge University Press, 1995. ix+256 pp. Maps. ISBN: 0521482232

    Directory of Open Access Journals (Sweden)

    Amelia Ying Qin

    2014-07-01

    Full Text Available Drawing upon his knowledge and understanding of literature, book culture, and vernacular culture of pre-modern China, Glen Dudbridge offers, in his unique reading of Kuang-i chi 廣異記 (The great book of marvels, insights into the religious experiences of lay society individuals of eighth century China. However, an inquisitive reader must ask the following questions: Can Kuang-i chi, a medieval collection of tales of encounters with the other world by the minor T’ang Dynasty official Tai Fu 戴孚 (fl. 760-780, chin-shih 757, be used for the purpose of the study of religious culture? How? and to what extent? What approaches would be effective in inquiring such a text and what kinds of conclusions can be drawn? Though not explicitly setting forth these questions, Dudbridge’s work serves as answers to them through explicitly defining the nature of Kuang-i chi to his study, discarding conventional categories and establishing new ones in his analysis, and associating Kuang-i chi to the “vernacular,” instead of official, or “centralized,” religious culture (p.63-4. Using a sharp historical focus on the collection, Dudbridge concentrates on the dynamics of change in religious practices of T’ang Dynasty that is rooted and reflected in such a vernacular religious culture....

  3. Collaborative pre-competitive preclinical drug discovery with academics and pharma/biotech partners at Sanford|Burnham: infrastructure, capabilities & operational models.

    Science.gov (United States)

    Chung, Thomas D Y

    2014-03-01

    There has been increased concern that the current "blockbuster" model of drug discovery and development practiced by "Big Pharma" are unsustainable in terms of cost (> $1 billion/approved drug) and time to market (10 - 15 years). The recent mergers and acquisitions (M&A), shuttering of internal research programs, closure of "redundant" sites of operations, senior management turnover and continued workforce reductions among the top 10 major pharmaceutical companies reflect draconian responses to reduce costs. However, the resultant exodus of intellectual capital, loss in motivation and momentum, and exit from early stage discovery programs by pharmaceutical companies has contributed to an "innovation deficit". Disease advocacy groups, investment communities and the government are calling for new innovative business models to address this deficit. In particular they are looking towards academia and clinical trials centers to catalyze new innovations in translational research. Indeed over the last decade many academic institutions have launched drug discovery centers largely comprising high-throughput screening (HTS) to accelerate "translational" research. A major impetus for this "open innovation" effort has been the National Institutes of Health (NIH) "Roadmap" and Molecular Libraries Initiative/Program (MLI/MLP), which is in its last year, and will be transitioned into the National Center for the Advancement of Translational Sciences (NCATS). With the end of Roadmap funding, general reduction in Federal government funding and its recent sequestration, academic drug discovery centers are being challenged to become selfsustaining, adding financial value, while remaining aligned with the missions of their respective academic non-profit institutions. We describe herein, a brief history of our bi-coastal Conrad Prebys Center for Chemical Genomics (Prebys Center) at the Sanford|Burnham Medical Research Institute (SBMRI), the key components of its infrastructure, core competencies of its fully integrated drug discovery expertise, best practices adopted in our day-to-day operations, and finally some of our current funding and collaboration and/or strategic alliance models for pre-competitive drug discovery with other academic/clinical partners, other governmental agencies, and with pharmaceutical and biotechnology companies. PMID:24409951

  4. Current barriers, challenges and opportunities for the development of effective STI vaccines: point of view of vaccine producers, biotech companies and funding agencies.

    Science.gov (United States)

    Dodet, Betty

    2014-03-20

    Several barriers limit the development of vaccines against sexually transmitted diseases (STIs). Critical scientific information is missing that makes the feasibility and the likelihood of success of vaccines against genital herpes, chlamydia, gonorrhea and trichomonas uncertain: the immunity induced by natural infection is absent or imperfect which seriously limits the capacity to define the types of immune responses that an effective vaccine must induce. Reliable animal models are lacking and a number of crucial clinical questions are still unanswered about the goal of these vaccines and definition of endpoints for clinical trials. In the absence of a clear recognition of the need for vaccines against these diseases, there is no motivation for public or private research and industry to invest in the development of vaccines against STIs. The STI burden should be evaluated not only in terms of mortality and morbidity, but also in terms of economic and psycho-social impact. A global public-private consortium could mobilize the joint efforts of all stakeholders involved in the research, development and implementation of STI vaccines of the public and private sectors; ensure that sufficient resources are applied to R&D of vaccines against these STIs; and provide the pull-push forces that are necessary to overcome the barriers to develop safe and effective vaccines against these diseases. PMID:23994377

  5. Vývoj a optimalizace metodiky pro detekci GMO brambor

    OpenAIRE

    ČERMÁKOVÁ, Jitka

    2008-01-01

    Genetically modified (GM) or transgenic crops, now more often called "Biotech crops" they are commercially cultivated since 1996. And also since 1996, the first year of commercialization of biotech crops, GM potatoes were cultivated in USA, Mexico, Canada and later in South Africa, China and India. The global area of approved biotech crops in 2006 was 102 million hectares and 22 countries grew biotech crops, 11 developing countries and 11 industrial countries. The Czech Republic is on of the ...

  6. An investigation into the impact of question structure on the performance of first year physics undergraduate students at the University of Cambridge

    OpenAIRE

    Gibson, Valerie; Jardine-Wright, Lisa; Bateman, Elizabeth

    2015-01-01

    This is the final published version of the article. It was originally published in the European Journal of Physics (Gibson V, Jardine-Wright L, Bateman E, European Journal of Physics 2015, 36, 045014, doi:10.1088/0143-0807/36/4/045014) http://dx.doi.org/10.1088/0143-0807/36/4/045014

  7. When Psychology Went Online: Review of "Psychological Aspects of Cyberspace: Theory, Research Applications", Edited by Azy Barak (Cambridge University Press, 2008

    Directory of Open Access Journals (Sweden)

    Tom Buchanan

    2008-01-01

    Full Text Available Azy Barak is well known for his prolific contributions to several areas of the literature dealing with psychological investigation of the Internet and related technologies, and also the exploitation of the Internet as a space in which the profession of psychology may be conducted. These efforts fall within the domain of what some call "cyberpsychology" - essentially, the application of psychology to the Internet - and that is the focus of this book. In this 300-page volume he has assembled an excellent collection of contributors, all familiar names who have done much to advance their respective fields of expertise. Many of the real pioneers in the area are represented here, bringing to the project a considerable depth and breadth of knowledge and experience. They are drawn from a variety of nations, institutions, and areas of psychology, and thus bring a variety of perspectives to the work.

  8. Weiss Max, In the Shadow of Sectarianism. Law, Shi‘ism and the Making of Modern Lebanon, Cambridge, Harvard University Press, 2010, 341 p.

    OpenAIRE

    Sabrina Mervin

    2013-01-01

    Reprenant à son compte le titre d’un article fort connu des historiens du chiisme (Hodgson 1955), Max Weiss se demande, dans le prologue de cet ouvrage, « How did the Lebanese Shi‘a become Sectarian ? ». Il poursuit par une explication de ce qu’il entend par sectarianism, et s’interroge ensuite sur son lien à la modernité, en s’appuyant sur les travaux d’Ussama Makdisi et d’Ayesha Jalal. On n’entrera pas ici dans des débats sur la définition et la traduction du terme ṭâ’ifiyya utilisé par les...

  9. Weiss Max, In the Shadow of Sectarianism. Law, Shi‘ism and the Making of Modern Lebanon, Cambridge, Harvard University Press, 2010, 341 p.

    Directory of Open Access Journals (Sweden)

    Sabrina Mervin

    2012-06-01

    Full Text Available Reprenant à son compte le titre d’un article fort connu des historiens du chiisme (Hodgson 1955, Max Weiss se demande, dans le prologue de cet ouvrage, « How did the Lebanese Shi‘a become Sectarian ? ». Il poursuit par une explication de ce qu’il entend par sectarianism, et s’interroge ensuite sur son lien à la modernité, en s’appuyant sur les travaux d’Ussama Makdisi et d’Ayesha Jalal. On n’entrera pas ici dans des débats sur la définition et la traduction du terme ṭâ’ifiyya utilisé par les...

  10. Book review of Capital in the Twenty-First Century, by Thomas Piketty. Cambridge, Massachusetts, London, England: The Belknap Press of Harvard Press, 2014, 605 pages

    Directory of Open Access Journals (Sweden)

    Paul Dobrescu

    2015-04-01

    Full Text Available “Every now and then, the field of economics produces an important book; this is one of them” (Cowen, 2014. These are the opening words of Tyler Cowen’s presentation of Thomas Piketty’s work, “Capital in the Twenty-First Century” (Piketty, 2014, in Foreign Affairs. This is a book that is visibly placed in all important bookstores around the world, widely debated, acclaimed, sold (over 1 million copies have been sold so far. It has been favorably reviewed or quoted in all major journals. The assessment of “Capital in the Twenty-First Century” by Paul Krugman, Nobel Economics Prize Laureate as a “magnificent, sweeping meditation on inequality”, is highly relevant: “This is a book that will change both the way we think about society and the way we do economics” (Krugman, 2014. Finally, Piketty’s book is included in the list of the year’s best books by prestigious journals, such as The Economist, Financial Times, The Washington Post, Observer, The Independent, Daily Telegraph; Financial Times and McKinsey have hailed it as the best book of 2014.

  11. The Cambridge Mindreading Face-Voice Battery for Children (CAM-C): complex emotion recognition in children with and without autism spectrum conditions

    OpenAIRE

    Golan, Ofer; Sinai-Gavrilov, Yana; Baron-Cohen, Simon

    2015-01-01

    Background: Difficulties in recognizing emotions and mental states are central characteristics of autism spectrum conditions (ASC). However, emotion recognition (ER) studies have focused mostly on recognition of the six ?basic? emotions, usually using still pictures of faces. Methods: This study describes a new battery of tasks for testing recognition of nine complex emotions and mental states from video clips of faces and from voice recordings taken from the Mindreading DVD. This...

  12. Cool stars, stellar systems, and the sun; Proceedings of the 6th Cambridge Workshop, Seattle, WA, Sept. 18-21, 1989

    Science.gov (United States)

    Wallerstein, George (Editor)

    1990-01-01

    The present conference on cool stars, stellar systems, and the sun encompasses stellar chromospheres and coronae, binary stars, the stellar evolution of contracting stars and red giants, stellar evolution abundances of the elements, mass loss and envelopes, and stellar pulsation. Specific issues addressed include theories regarding the acoustic and magnetic heating of stellar chromospheres and coronae, stellar granulation, wave heating in magnetic flux tubes, observations of the solar Ca-II lines, longitudinal-transverse magnetic tube waves in the solar atmosphere, radio emission from rapidly rotating cool giant stars, and spot temperatures and area coverages on active dwarf stars. Also addressed are the optical and UV spectra of RS-CVn stars, emission lines from T-Tauri stars, the spectroscopy of HR1614 group stars, red giants in external galaxies, the rotation of evolved stars, the transition from red giant to planetary nebula, and radiative transfer in the dynamic atmospheres of variable stars.

  13. Reply to L.M. Brown et al. "Brief history of the Cambridge STEM aberration correction project and its progeny" in Ultramicroscopy 157, 88 (2015).

    Science.gov (United States)

    Urban, K W; Rose, H

    2016-02-01

    We comment on a Short Communication recently published in Ultramicroscopy in which Brown et al. criticize our description of the time sequence of events in the development of aberration correction systems in electron optics during the 1990s put forward in the introduction to the Ultramicroscopy April 2015 Special Issue. We present an analysis of the published literature furnishing evidence that our description is correct. PMID:26624509

  14. β/δ-PrIT1, a highly insecticidal toxin from the venom of the Brazilian spider Phoneutria reidyi (F.O. Pickard-Cambridge, 1897).

    Science.gov (United States)

    de Oliveira, Leida Calegário; Campos, Fabiana V; Figueiredo, Suely Gomes; Cordeiro, Marta N; Adaime, Beatriz R; Richardson, Michael; Pimenta, Adriano M C; Martin-Eauclaire, Marie-France; Beirão, Paulo S L; De Lima, Maria Elena

    2015-09-15

    A potent insecticidal toxin, β/δ-PrIT1, molecular mass of 5598.86 [M+H](+), was characterized from Phoneutria reidyi spider venom. Its partial amino acid sequence showed high similarity with insecticidal spider toxins from the genus Phoneutria. β/δ-PrIT1 was very toxic (LD50 = 4 nmol/g) to flies (Musca domestica), but not to mice (Mus musculus). Kinetic studies showed that (125)I-β/δ-PrIT1 binds to two distinct sites in insect sodium channels, with close affinity (Kd1 = 34.7 pM and Kd2 = 35.1 pM). Its association is rather fast (t1/2(1) = 1.4 min, t1/2(2) = 8.5 min) and its dissociation is a slower process (t1/2(1) = 5.4 min, t1/2(2) = 32.8 min). On rat brain synaptosomes β/δ-PrIT1 partially competed (∼30%) with the beta-toxin (125)I-CssIV, but did not compete with the alpha-toxin of reference (125)I-AaII, nor with the beta-toxin (125)I-TsVII. On cockroach nerve cord synaptosomes, β/δ-PrIT1 did not compete with the anti-insect toxin (125)I-LqqIT1, but it competed (IC50 = 80 pM) with the "alpha-like" toxin (125)I-BomIV. In cockroach neurons, β/δ-PrIT1 inhibited the inactivation of Nav-channels and it shifted the sodium channel activation to hyperpolarizing potentials. These results indicate two different binding sites for β/δ-PrIT1, leading to two different pharmacological responses. β/δ-PrIT1 is one of the most toxic spider toxins to insects without apparent toxicity to mammals, and provide new model for the development of insecticides. PMID:26220799

  15. When Psychology Went Online: Review of "Psychological Aspects of Cyberspace: Theory, Research Applications", Edited by Azy Barak (Cambridge University Press, 2008)

    OpenAIRE

    Tom Buchanan

    2008-01-01

    Azy Barak is well known for his prolific contributions to several areas of the literature dealing with psychological investigation of the Internet and related technologies, and also the exploitation of the Internet as a space in which the profession of psychology may be conducted. These efforts fall within the domain of what some call "cyberpsychology" - essentially, the application of psychology to the Internet - and that is the focus of this book. In this 300-page volume he has assembled an...

  16. Strategy: The Logic of War and Peace rev. and enlarged ed. by Edward N. Luttwak Cambridge, MA: The Belknap Press of Harvard University Press, 2001 / Book Review

    OpenAIRE

    Wirtz, James J.

    2003-01-01

    In the 1980s scholars in the ªelds of history and political science rediscovered the work of Carl von Clausewitz, the Prussian philosopher of war. This renewed interest sparked a brief revival of the study of war and strategy (the latter of which encompasses efforts to exploit war’s dialectic to achieve military and political victory). After relying for decades on operations research to minimize the likelihood of nuclear war by bolstering deterrence—an approach that largely eli...

  17. Review of the volume Applied Social Sciences: Sociology, edited by Patricia-Luciana Runcan, Georgeta Rata and Mihai-Bogdan Iovu, published by Cambridge Scholars Publishing, 2013

    Directory of Open Access Journals (Sweden)

    Ana CARAS

    2013-06-01

    Full Text Available The present paper aims at presenting the main ideas of the volume Applied Social Sciences: Sociology, appeared as a result of the International Conference of Applied Sciences, which emerged as a multidisciplinary forum. The volume structured in 6 chapters exposes gradually themes such as culture and identity, emigration and immigration, school organisation and educational opportunities, vulnerable people, groups and populations, communication and social relations and perceptions, attitudes, values, all those aspects being treated in a sociological context.

  18. Southern Ocean cephalopods: life cycles and populations (Proceedings of the symposium held at Kings College Cambridge, 5–9 July 1993)

    OpenAIRE

    Rodhouse, P.G; Piatkowski, U.; Lu, C. C.

    1994-01-01

    The first systematic sampling in the Southern Ocean to capture cephalopods took place 120 years ago aboard HMS Challenger. Over the next century taxonomic knowledge was advanced by expeditions including the Mission du Cap Horn (France), the Valdivia Deep Sea Expedition (Germany), the Discovery expeditions (UK) the Eltanin (USA) and Academic Knipovitch (USSR). Over the last decade Southern Ocean cephalopod research has at last progressed beyond the descriptive phase and is rapidly joining othe...

  19. David A. BELL, The Cult of the Nation in France. Inventing Nationalism, 1680-1820, Cambridge (Mas.) et Londres, Harvard University Press, 2001, 304 p.

    OpenAIRE

    Guilhaumou, Jacques

    2008-01-01

    David Bell, professeur d'histoire à la Johns Hopkins University, ne considère pas la nation comme une réalité dont l'essence aurait été définie par les Français du XVIIIe siècle. Dans la lignée de réflexions anglo-américaines (en particulier les travaux de Benedict Anderson, Ernest Gellner, Éric Hobsbawm et Anthony Smith), il l'appréhende plutôt comme un produit de la volonté politique, par le fait d'un artefact politique à construire dans un processus d'invention du nationalisme. Il donne ai...

  20. Book Review: Intellectual Property Law and Innovation by W. van Caenegem, Cambridge University Press, Melbourne, Australia , ISBN 978-0-52183-757-6

    NARCIS (Netherlands)

    Brack, Antoni

    2007-01-01

    This is in several respects an attractive publication. In over 200 pages, a wealth of insights is offered to the reader about the legal instruments to support and protect industrial innovations. The text is supplemented by a list of acronyms, tables of statutes and cases, an extensive bibliography a

  1. Review of: János Kornai, By Force of Thought: Irregular Memoirs of an Intellectual Journey. Cambridge (Mass.): The MIT Press, 2007

    OpenAIRE

    Chilosi, Alberto

    2007-01-01

    Kornai's autobiography presents an interesting perspective of the intellectual environment of a Central European country of real socialism such as Hungary, from the Stalinist after-war years to the progressively more relaxed, but still constraining, atmosphere of the sixties and later. Of specific interest for the economist is Kornai's inside witness of the actual functioning of a “real” socialist planned economy, and of the political processes related to it. In the intellectual side of the a...

  2. Review of Andrés Solimano, International Migration in the Age of Crisis and Globalisation. Historical and Recent Experiences, Cambridge University Press, 2010. 223 Pp.

    Directory of Open Access Journals (Sweden)

    Dirina Claudiu – Ciprian

    2015-12-01

    Full Text Available “International Migration in the Age of Crisis and Globalization. Historical and Recent Experiences” represents a work of major interest in the field of migration and globalization. Apparently two concepts that relate one to another, on a background of major population dynamics, the two notions are the two important pillars in what might perfectly be described as a complex analysis of migration, starting from the elements that have initiated it, and culminating with a fine comparison of positive and negative aspects of this phenomenon.

  3. [Rets. rmt. : Stefan Halper, Jonathan Clarke. America Alone : The Neo-Conservatives and the Global Order. Cambridge 2004] / Maria Mälksoo

    Index Scriptorium Estoniae

    Mälksoo, Maria, 1979-

    2005-01-01

    Traditsiooniliste konservatiivide S. Halperi ja J. Clarki raamat harutab lahti neokonservatiivse ilmavaate, selle liikumise kujunemise ja mõjuvõimu laienemise ning näitavad, kuidas uuskonservatiivid võtsid võimu USA Riigidepartemangus ja Pentagonis

  4. A new Gray’s anatomy of English grammar : review article on R. Huddleston and G. Pullum, ‘The Cambridge grammar of the English language’, 2002.

    OpenAIRE

    Leech, Geoffrey

    2004-01-01

    This article reviews Huddleston & Pullum (2002) from the viewpoint of a co-author of Quirk, Greenbaum, Leech & Svartvik (1985). (This author, however, makes no claim whatsoever to represent the views of the other authors of Quirk et al.) Particular attention is paid to some of the more controversial aspects of Huddleston & Pullum's analysis. It is argued that the two grammars, although similar in their comprehensively wide coverage of English, are not strictly comparable, in that Huddleston &...

  5. 老而弥新的剑桥大学出版社%The Press of Cambridge University Shows both Traditional and Modern

    Institute of Scientific and Technical Information of China (English)

    安华

    2002-01-01

    @@ 在英国最高学府剑桥大学城孕育和成长的剑桥大学出版社,已走过了150年的道路.今天它仍然充满活力,老而弥新,每年出版约2500种图书,150多种学术性期刊,远销世界上200个国家.我国几代学生和科学技术工作者,很多也都读过剑桥出版的教科书、学术书,用过剑桥英语词典,留有较为深刻的印象.

  6. 事实状态与Ereignis%"Facticity and Ereignis", in Daniel O.Dahlstrom ed., Interpreting Heidegger: Critical Essays,Cambridge University Press, 2011

    Institute of Scientific and Technical Information of China (English)

    T.希恩; 周炼

    2013-01-01

    “存在”这一概念极易误导人们对于海德格尔思想的理解.立足于从“存在”到“意义”的现象学还原,我们有理由认为,当海德格尔谈论存在时,他谈的是现象学意义上的意义.这一解释可以在早期海德格尔关于事实状态(Faktizit~it)和后期海德格尔关于Ereignis的论述中得到印证和理解.事实状态和Ereignis说的是一回事:保持意义-给予过程的敞开.鉴于“存在”在海德格尔研究文献中的长期使用,本文将首先澄清海德格尔在何种意义上使用“存在”一词,并根据这一澄清重新解释世界、真、Ereignis、事实状态等重要概念.

  7. Book review of 'Days on the family farm : from the Golden Age through the Great Depression' by Carrie A. Meyer, Cambridge : University of Minnesota Press, 2007.

    OpenAIRE

    Mughal, Muhammad Aurang Zeb

    2008-01-01

    Meyer, Associate Professor in Economics at George Mason University, in Days On The Family Farm recapitulates the times of the Golden Age of Agriculture, the Great Depression and the two World Wars with reference to economic setting and community life on a Midwestern family farm in America from the beginning of the twentieth century to World War II through the daily diary of a farmwife May Lyford Davis.

  8. Gérard Dumenil and Dominique Lévy, The Crisis of Neoliberalism, Harvard University Press, Cambridge, Massachussetts, London, England, 2011.

    Directory of Open Access Journals (Sweden)

    Ozgur Gün

    2011-12-01

    Full Text Available Avec leur dernier ouvrage, Gérard Duménil et Dominique Lévy font, une fois encore, la démonstration de la puissance explicative de leur économie politique marxiste. Dans la mesure où, en temps de crise, les recours aux hétérodoxies en général et à Marx en particulier, bien que souvent éphémères, sont toujours nombreux (aussi bien dans les discours économiques profanes qu’académiques, cette démonstration pourrait paraître dispensable. Or, il n’en est rien, les enjeux analytiques et politiques...

  9. Human Immunodeficiency Virus Seroprevalence among Inmates of the Penitentiary Complex of the Region of Campinas, State of São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Neusa Maria Osti

    1999-07-01

    Full Text Available Six hundred and ninety three male inmates from three penitentiaries, two (A and B maximum-security systems and one (C minimum-security facility, located in Campinas, State of São Paulo, Brazil were studied for the presence of human immunodeficiency virus (HIV antibodies, using a cross-sectional design. The search for anti-HIV antibodies in 693 samples of sera collected was carried out by two serological tests: (a the Microparticle enzyme immunoassay-HIV-1 and HIV-2 (MEIA (Abbott Laboratories and (b the Western Blot-HIV-1 (WB (Cambridge Biotech Corporation to confirm positive results with MEIA. Sera reactivity for HIV antibodies was 14.4%. The highest frequency of anti-HIV antibodies was found in the A and B maximum-security prisons: 17% and 21.5%, respectively. In prison C, the frequency of reagents was 10.9%. Seventy three inmates, initially negative in the MEIA test, were checked again five and seven months later. Three of them, all from the maximum-security facilities, became reactive in the MEIA test, with confirmation in the WB, suggesting that serological conversion had occurred after imprisonment.

  10. GMO Biosafety Management, Suggestions and Biotech Public Acceptance in China%我国转基因作物安全管理体系介绍、发展建议及生物技术舆论导向

    Institute of Scientific and Technical Information of China (English)

    康乐; 陈明

    2013-01-01

    17年间,转基因作物在全球的种植面积逐渐扩大了100倍,截止2012年已经达到1.7亿公顷,产生了巨大的经济效益、社会效益和生态效益.我国转基因作物发展迅速,目前已有7种转基因植物获得生产应用安全证书,转基因棉花占全国棉花种植面积的80%.为保障转基因生物安全,我国已建立了完整的转基因生物安全管理体系,包括安全管理机构、政策、法规,转基因生物及其产品如环境安全评价、食品安全性评价及成份测定的技术标准.另一方面,我国转基因作物安全管理及安全评价体系仍然需要完善,本文针对现阶段存在的问题提出了改进及完善的建议.同时,本文分析了我国转基因作物舆情,列举了近来国内外所谓的转基因作物安全事件并揭示了事件的真实情况,提倡理性看待转基因作物的发展,为我国转基因研发与产业化营造积极的舆论氛围.%GM crops have been commercialized for 17 years all over the world,and brought great economic,social and ecological benefits to growers and the world.China has approved 7 GM crops for planting,among which Bt cotton accounts for 80% of cotton planting area.In this article,we reviewed development and application of GM crop internationally and domestically.The policy on GM crops in China including regulations,guidelines,food and environmental safety assessment are also briefly introduced.Some existing problems and suggestions on China's biosafety management and regulator process are also described in this review.Finally,the authors advocate rational understanding of GM crops to create a positive atmosphere for public acceptance,which will benefit research,development and commercialization of GM crops in China.

  11. (Asian) Life (in Asia) - Book reviews of Margaret Sleeboom-Faulkner (Ed.): Frameworks of Choice, Amsterdam, Amsterdam Press 2010 and Aihwa Ong & Nancy Chen: Asian Biotech, Durham & London, Duke University Press 2010

    DEFF Research Database (Denmark)

    Wahlberg, Ayo

    2011-01-01

    This article is concerned with the idea of societal 'spaciousness' and its relationship to individual and collective autonomy. These issues are analyzed in the context of the eviction of a self-managed social center of left-radical activists in Copenhagen and the protests and public debate that f...

  12. Create a translational medicine knowledge repository - Research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech companies: how will they avoid relearning old lessons?

    Directory of Open Access Journals (Sweden)

    Marincola Francesco M

    2011-05-01

    Full Text Available Abstract Pharmaceutical industry consolidation and overall research downsizing threatens the ability of companies to benefit from their previous investments in translational research as key leaders with the most knowledge of the successful use of biomarkers and translational pharmacology models are laid off or accept their severance packages. Two recently published books may help to preserve this type of knowledge but much of this type of information is not in the public domain. Here we propose the creation of a translational medicine knowledge repository where companies can submit their translational research data and access similar data from other companies in a precompetitive environment. This searchable repository would become an invaluable resource for translational scientists and drug developers that could speed and reduce the cost of new drug development.

  13. Sipuleucel-T (Provenge(®))-Autopsy of an Innovative Paradigm Change in Cancer Treatment: Why a Single-Product Biotech Company Failed to Capitalize on its Breakthrough Invention.

    Science.gov (United States)

    Jarosławski, Szymon; Toumi, Mondher

    2015-10-01

    Approved by the US Food and Drug Administration (FDA) in 2010, sipuleucel-T (Provenge(®)) was the first 'personalized' cancer vaccine for the treatment of prostate cancer in a metastatic, non-symptomatic population of 30,000 men in the USA. Sipuleucel-T is prepared individually for each patient and infused in three sessions over a period of 1 month. However, in 2015, Dendreon, the owner of sipuleucel-T, filed for bankruptcy. This opinion paper reviews the probable reasons this innovative product failed to achieve commercial success. PubMed and internet searches were performed focused on pricing, reimbursement, and market access. We found that sipuleucel-T's FDA approval was delayed by 3 years, reportedly because of the vaccine's new mechanism of action. Sipuleucel-T was cleared by the European Medicines Agency 2 years later, but other national agencies were not approached. It was priced at $US93,000 for a course of treatment, and this high price combined with the company's late securement of reimbursement for the vaccine by the US Centers for Medicare and Medicaid Services (CMS) resulted in another year's delay in accessing the market. Despite a positive recommendation by the National Comprehensive Cancer Network, sipuleucel-T's complex administration, high price, and uncertainty about the reimbursement status deterred doctors from prescribing the product. Furthermore, the vaccine's supply was limited during the first year of launch due to limited manufacturing capacity. In addition, two oral metastatic prostate cancer drugs with similar survival benefits reached the US market 1 and 2 years after sipuleucel-T. Also, even though Dendreon's market capitalization topped $US7.5 billion following the FDA's approval of sipuleucel-T, this value degraded gradually until the firm's bankruptcy 5 years later. We conclude that the bankruptcy of Dendreon was largely due to the delay in securing FDA approval and CMS coverage, as well as the high cost that had to be incurred by providers up-front. Licensing sipuleucel-T to a pharmaceutical company more experienced in the market access pathway may have saved the company and the product. PMID:26403092

  14. 简评阿兰·贝克的《地理学与历史学——架起跨越鸿沟的桥》%Review:Alan Baker,Geography and History:Bridging the Divide,Cambridge University Press,Cambridge(2003)

    Institute of Scientific and Technical Information of China (English)

    段伟

    2007-01-01

    历史地理学诞生在西方,西方学者对其理论的探讨也早于我国学者。在20世纪上半叶,学者曾多次讨论历史地理学的性质问题。英国著名历史地理学家达比(H.C.Darby)先生也数次撰文阐述,其思想深刻影响了我国学界,他所认为的历史地理学属于地理学的思想至今在我国还占主流地位。与我国学界关于历史地理学理论的热烈探讨一样,论述历史地理学理论的文章在西方更是多不胜数,著作也有不少,理论层出不穷。但敢于以“地理学与历史学”作为著作题目进行宏观阐述的学者却非常少。1901年,乔治(H.B.George)先生以一个历史学家的视角出版《地理学与历史学的关系》,是第一部以之为题的著作,重版多次,广受读者喜爱。这之后,大概由于题目涵盖量太大,一直没有同类著作出现。

  15. IMPLICATIONS OF RICE BIOTECHNOLOGY ON OPTIMAL RICE CROP ROTATION IN THE MISSISSIPPI RIVER DELTA REGION

    OpenAIRE

    Annou, Mamane Malam; Thomsen, Michael R.; Hansen, James M.; Wailes, Eric J.; Cramer, Gail L.

    2001-01-01

    Availability of new herbicide-resistant biotech rice varieties may affect traditional rice rotation practices to control red rice and enhance yields. This research evaluates the adoption of biotech rice and its effects on the current practice of crop rotation in the Mississippi River Delta region. The optimal utilization of biotech rice rotation is analyzed using a nonlinear mathematical programming model with mixed integers. Optimal rotation was found to be sensitive to the technology fee, r...

  16. Random – walk model for impedance spectroscopy data analysis in ionic materials

    Czech Academy of Sciences Publication Activity Database

    Depak, P.; Wágner, T.; Zima, Vítězslav; Shimakawa, K.

    Cambridge: Trinity College Cambridge, 2014. [Doped Amorphous Chalcogenides and Devices. 27.03.2014-28.03.2014, Cambridge] Institutional support: RVO:61389013 Keywords : impedance spectroscopy * ionics conductors * chalcogenide glasses Subject RIV: CA - Inorganic Chemistry

  17. Christos C. Tsagalis The Oral Palimsest. Exploring Intertextuality in the Homeric Epics : Center for Hellenic Studies, Harvard University Press, Cambridge, Massachusetts, and London, England, 2008, ix + 325 pp.

    OpenAIRE

    Zecchin de Fasano, Graciela Cristina

    2008-01-01

    Tsagalis intenta estudiar la relación entre tradiciones poéticas reconocibles, la intertextualidad meta-tradicional, las asociaciones entre Homero y tradiciones reconstruidas de antiguos estratos indoeuropeos y,  nalmente, la combinación de partes que interactúan, cuyo sentido pleno solamente aparece cuando se las inserta dentro de un amplio intertexto.

  18. Explaining Economic Growth in China: Testing Sociological Tools for Validity A Review on Book: Nee V., Opper S. (2012) Capitalism from Below: Markets and Institutional Change in China, Cambridge, MA: Harvard University Press

    OpenAIRE

    Alexander Kurakin

    2014-01-01

    Today it makes little sense to ask a question, why social scholars are interested in China’s economy as far as the answer is obvious. The growth rate of Chinese economy and duration of its growth period are stunning. It is likely that in the nearest future China will outrun USA in terms of GDP and become the largest economy in the world. Moreover, China has made a huge progress in GDP per capita. But this is not the only reason for the great interest in China. Chinese communist party is still...

  19. La autoridad de las administraciones internacionales en la sociedad internacional en "The Authority of International Administrations in International Society", Review of International Studies, Vol.32/3., Cambridge Journals, Reino Unido, 2006.

    Directory of Open Access Journals (Sweden)

    Dominik ZAUM

    2009-02-01

    Full Text Available En este artículo se analiza cómo las administraciones internacionales que ejercen un poder gubernamental en territorios post conflicto justifican su autoridad política sin tener legitimidad democrática. En el artículo se estudia el establecimiento, los mandatos y las prácticas de gobierno de las administraciones de Bosnia, Kosovo y Timor Oriental y se identifican cinco fundamentos de la autoridad: el consentimiento, la delegación, el mantenimiento de la paz y la seguridad, el fomento de los derechos humanos y la democracia, y la disposición para gobernar. No obstante, todos estos aspectos son cuestionables. En concreto, la autoridad de las administraciones internacionales se debilita debido a sus prácticas, a que no existe la obligación rendir cuentas y a la efectividad limitada a la hora de disponer gobierno. Para concluir, en el artículo se destacan algunas posibles vías de refuerzo de la autoridad de las administraciones internacionales. In this article there is analyzed how the international administrations that exercise a governmental power in post conflict territories justify their political authority without having democratic legitimacy. In the article it is studied, both the establishment, the mandates and the practices of government of the international administrations of Bosnia, Kosovo and East Timor, and they are identified five sources for this authority: the assent, the delegation, the maintenance of the peace and the safety, the promotion of the human rights and the democracy, and the disposition to govern. Nevertheless, all these aspects are questionable. Concretely, the authority of the international administrations is weakened due to its practices, to the unexistence of any obligation for accountability and to the limited efficiency at the moment of arranging government. To conclude, in the article are outlined some possible ways for the reinforcement of the authority of the international administrations.

  20. Calculated Sunspot and Quiet-Sun Mg II Profiles Compared With IRIS DataEugene Avrett and Hui TianHarvard-Smithsonian Center for Astrophysics60 Garden Street, Cambridge, MA 02138

    Science.gov (United States)

    Avrett, Eugene H.

    2014-06-01

    A new sunpsot model has been derived, consistent with the SUMER atlas data of Curdt, et al. and Mg II profile data from IRIS. Comparisons are made with Quiet-Sun results from both sources. It is necessary to include molecules in the sunspot model not only account for the low brightness temperatures near 1850 /AA but also for the density variations higher in the atmosphere. The minimum temperature is roughly 2500 K in the sunspot model and 4500 K for the quiet Sun. The Mg II H line profile is centrally reversed in both cases, with the peak intensity originating where the temperature rises abruptly from the minimum value. The line center is formed at the top of the chromosphere where the temperature rises abruptly from 10,000 K into the chromosphere-corona transition region. The calculated Mg II line center intensity is much smaller than observed, for models constrained by the EUV continuum data.

  1. DE MIGUEL GONZÁLEZ, R. y DONERT, K. (EDITORES (2014 Innovative Learning Geography in Europe: New Challenges for the 21st Century. Cambridge Scholars Publishing. 233 pp. ISBN (13: 978-1-4438-5508-2.

    Directory of Open Access Journals (Sweden)

    María Luisa Gómez Ruiz

    2014-12-01

    Full Text Available   Este libro editado por los profesores Rafael de Miguel y Karl Donert muestra un gran abanico de posibilidades para aprender geografía desarrollando métodos y técnicas innovadoras propias de las oportunidades que ofrece el siglo XXI. El alcance de todas ellas es cada vez más amplio gracias a las nuevas y emergentes tecnologías que favorecen cada vez más el acceso a la información geográfica o geoinformación y a los recursos geo-media. 

  2. Intelligent robots; Proceedings of the Third International Conference on Robot Vision and Sensory Controls RoViSeC3, Cambridge, MA, November 7-10, 1983. Parts 1 & 2

    Science.gov (United States)

    Casasent, D. P.; Hall, E. L.

    1984-01-01

    Aspects of pattern recognition for intelligent robots are discussed, taking into account linear algebra based object recognition algorithms for computer vision, planar object recognition by the computer vision method, real time textured-image segmentation based on noncausal Markovian random field models, model driven vision to control a surface finishing robot, robotic acquisition of jumbled parts from bins by visual and tactile guidance, and imaging using eddy current sensors. Other subjects explored are related to curved object recognition for robot vision, robot image understanding, robot applications, three-dimensional measurements for robot vision, robot vision, tactile and multirobot sensors, and precision robot vision measurements. Attention is given to mode locked lasers in modulation rangefinders, advanced architectures for factory vision, hierarchical contour coding and generalization of shape, problems in three-dimensional imaging, a vision system to identify car body types for a spray painting robot, and an adaptive gas metal arc welder.

  3. Learning Outcomes Associated with Classroom Implementation of a Biotechnology-Themed Video Game

    Science.gov (United States)

    Barko, Tim; Sadler, Troy D.

    2013-01-01

    The educational video game Mission Biotech provides a virtual experience for students in learning biotechnology materials and tools. This study explores the use of Mission Biotech and the associated curriculum by three high school teachers and their students. All three classes demonstrated gains on a curriculum-aligned test of science content.…

  4. Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy

    DEFF Research Database (Denmark)

    Strange, Michael Stewart

    2009-01-01

    Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy (Cambridge: Cambridge University Press), 254pp. Udgivelsesdato: 2009......Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy (Cambridge: Cambridge University Press), 254pp. Udgivelsesdato: 2009...

  5. Big Data, Small Media

    Directory of Open Access Journals (Sweden)

    Grant Bollmer

    2014-08-01

    Andrew Dubber Radio in the Digital Age Polity, Cambridge, 2013   Charles Ess Digital Media Ethics, Second Edition Polity, Cambridge, 2014   Graeme Kirkpatrick Computer Games and the Social Imaginary Polity, Cambridge, 2013   Dhiraj Murthy Twitter: Social Communication in the Twitter Age Polity, Cambrige, 2013   Jill Walker Rettberg Blogging, Second Edition Polity, Cambridge, 2014

  6. The Role of Transgenic Crops in the Future of Global Food and Feed

    OpenAIRE

    O. Škubna; H. Řezbová

    2012-01-01

    The paper is aimed on the problematic of biotech crops planting (GM, transgenic crops). The main aim of this paper is to analyze the trends in the main biotech crops planting groups in the sense of their use for food and feed in the future. The selected groups of biotech crops analyzed in this article are soybeans, maize (corn), cotton and rapeseed (canola). The used methods are chain and basic indexes and regression analysis of times series/ trend data - for predicting on next four years (20...

  7. Scientific Opinion on the safety and efficacy of vitamin D3 (cholecalciferol as a feed additive for pigs, piglets, bovines, ovines, calves, equines, chickens for fattening, turkeys, other poultry, fish and other animal species or categories, based on a dossier submitted by Fermenta Biotech Ltd

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP

    2013-07-01

    Full Text Available The principal physiological role of vitamin D in all vertebrates is in calcium and phosphorus homeostasis. The classic clinical deficiency syndrome is rickets. The FEEDAP Panel notes that for turkeys for fattening, equines, bovines, ovines and pigs the maximum content for vitamin D3 in feed does not provide any margin of safety, and that, except for pigs, the maximum content is above the upper safe level, according to National Research Council data when animals were fed a supplemented diet for more than 60 days. No safety concern was identified for the use of vitamin D3 in chickens for fattening and fish. The FEEDAP Panel is not in a position to draw final conclusions on the safety of vitamin D for target animals but considers the current maximum contents temporarily acceptable pending a review of the recent scientific literature. Current nutritional surveys in 14 European countries showed that vitamin D intake is sufficiently below the upper safe limit. The FEEDAP Panel assumes that foodstuffs of animal origin were produced following current production practices, including vitamin D3 supplementation of feed and concludes that the use of vitamin D in animal nutrition at the currently authorised maximum dietary content has not and will not cause the tolerable upper intake level to be exceeded. Vitamin D3 should be considered as irritant to skin and eyes, and as a skin sensitiser. Inhaled vitamin D3 is highly toxic; exposure to dust is harmful. No risk to the environment resulting from the use of vitamin D3 in animal nutrition is expected. The vitamin D3 under application is regarded as an effective dietary source of the vitamin in animal nutrition.

  8. Scientific Opinion on the safety and efficacy of vitamin D3 (cholecalciferol) as a feed additive for pigs, piglets, bovines, ovines, calves, equines, chickens for fattening, turkeys, other poultry, fish and other animal species or categories, based on a dossier submitted by Fermenta Biotech Ltd

    OpenAIRE

    EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

    2013-01-01

    The principal physiological role of vitamin D in all vertebrates is in calcium and phosphorus homeostasis. The classic clinical deficiency syndrome is rickets. The FEEDAP Panel notes that for turkeys for fattening, equines, bovines, ovines and pigs the maximum content for vitamin D3 in feed does not provide any margin of safety, and that, except for pigs, the maximum content is above the upper safe level, according to National Research Council data when animals were fed a supplemented diet fo...

  9. 6th Annual European Antibody Congress 2010: November 29-December 1, 2010, Geneva, Switzerland.

    Science.gov (United States)

    Beck, Alain; Wurch, Thierry; Reichert, Janice M

    2011-01-01

    The 6th European Antibody Congress (EAC), organized by Terrapinn Ltd., was held in Geneva, Switzerland, which was also the location of the 4th and 5th EAC. As was the case in 2008 and 2009, the EAC was again the largest antibody congress held in Europe, drawing nearly 250 delegates in 2010. Numerous pharmaceutical and biopharmaceutical companies active in the field of therapeutic antibody development were represented, as were start-up and academic organizations and representatives from the US Food and Drug Administration FDA. The global trends in antibody research and development were discussed, including success stories of recent marketing authorizations of golimumab (Simponi®) and canakinumab (Ilaris®) by Johnson & Johnson and Novartis, respectively, updates on antibodies in late clinical development (obinutuzumab/GA101, farletuzumab/MORAb-003 and itolizumab/T1 h, by Glycart/Roche, Morphotek and Biocon, respectively) and success rates for this fast-expanding class of therapeutics (Tufts Center for the Study of Drug Development). Case studies covering clinical progress of girentuximab (Wilex), evaluation of panobacumab (Kenta Biotech), characterization of therapeutic antibody candidates by protein microarrays (Protagen), antibody-drug conjugates (sanofi-aventis, ImmunoGen, Seattle Genetics, Wyeth/Pfizer), radio-immunoconjugates (Bayer Schering Pharma, Université de Nantes) and new scaffolds (Ablynx, AdAlta, Domantis/GlaxoSmithKline, Fresenius, Molecular Partners, Pieris, Scil Proteins, Pfizer, University of Zurich) were presented. Major antibody structural improvements were showcased, including the latest selection engineering of the best isotypes (Abbott, Pfizer, Pierre Fabre), hinge domain (Pierre Fabre), dual antibodies (Abbott), IgG-like bispecific antibodies (Biogen Idec), antibody epitope mapping case studies (Eli Lilly), insights in FcγRII receptor (University of Cambridge), as well as novel tools for antibody fragmentation (Genovis). Improvements of

  10. 生物产业与生物经济

    Institute of Scientific and Technical Information of China (English)

    王宏广

    2004-01-01

    At the turn of 21 th century, breakthroughs have been made continuously in the biology technology. That gives a great help to the quick emergence of biotech industry. Some tendencies can be seen in the industry: 1) Biotech has become the research focus in many countries. 2)Biotech industry has been the emphasis of international high-tech and economic competition.3) Biology economy is becoming a new economic growth point after Internet.4)Biology security has become the key of the state security. The emergence of biotech industry will accelerate the formation of the 4th economy upsurge and will have great effect on the world economy and the development of human society.

  11. Estonian science breeds world-class researches / ToivoTänavsuu, Hille Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2010-01-01

    Eesti teadusfirmadest: biotehnoloogia ettevõtted Celecure AS, Protobios OÜ, Icosagen AS, Asper Biotech AS ja Solis BioDyne OÜ, geenitehnoloogia firma Genorama OÜ, keemiatehnoloogia ettevõte AS Cambrex Tallinn

  12. Eesti teadlaste HIV-vaktsiini süstitakse katseks aafriklastele / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 5. apr., lk. 2. Tartu teadlaste leiutatud ning Soome biotehnoloogiafirma FIT Biotech arendatavat vaktsiini katsetatakse Lõuna-Aafrika Vabariigis 60 surmaviirusega nakatunud inimese peal. Lisa: Eestlaste HIV-vaktsiini senine lugu

  13. A GOLDEN HANDSHAKE FOR CH NA'S B OFUEL

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Friendly policies for overseas investors to invest in China's biofuel sector have influenced partnerships between domestic and foreign companies to develop the alternative to fossil fuel. For example, Green Biologics (GBL), a British biotech company, has

  14. Experiment list: SRX029315 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available | cell type=CD34+CD133+ hematopoietic progenitor cells (HPCs) || antibody=anti-GABP-alpha || antibody manufacturer=Santa Cruz Biotech...nology http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/e

  15. Small company mergers--good for whom?

    Science.gov (United States)

    Maybeck, Vanessa; Bains, William

    2006-11-01

    An analysis of 105 mergers among small UK biotech companies over a 10-year period shows that the improvement of shareholder positions, rather than product pipelines or business opportunities, is the main motivation for such transactions. PMID:17093475

  16. Keeping enzymes kosher

    DEFF Research Database (Denmark)

    Fischer, Johan

    2015-01-01

    Biotech companies increasingly seek certification for compliance with religious and dietary requirements in order to address new consumer markets. Technology plays a crucial role in such inspections alongside centuries old traditions and practices...

  17. Life Science Forum showcases regional research, new companies

    OpenAIRE

    Trulove, Susan

    2009-01-01

    The Fourth Annual Southwest Virginia Life Science Forum on Monday, Oct. 4, will showcase New River Valley biotech companies' research and job opportunities, and be a resource for the ACC Interdisciplinary Forum for Discovery in Life Sciences.

  18. Development of carotenoid-enriched vegetables with increased nutritional quality and visual appearance

    Science.gov (United States)

    Carotenoids are a class of red, orange and yellow pigments widely distributed in nature. Biotech approach has been proved to be effective in successfully engineering of carotenoid content in food crops with better health and visual appearance....

  19. Eestis levinud HIVi erilisus jätab nakatunud vaktsiinilootuseta / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2002-01-01

    Soome biotehnoloogiafirma FIT Biotech on loobumas kavast katsetada Eesti teadlaste leiutatud vaktsiini ka siinsete HIV-positiivsete katserühmal, sest Eestis on levinud maailmas üliharuldane HI-viiruse G-alatüüp

  20. Beyond The Needle: Biotech’s Delivery Challenge

    OpenAIRE

    FELCONE, LINDA HULL

    2004-01-01

    Some biotech companies are devoting sizeable resources to finding more mainstream forms of drug delivery, including oral, transdermal, inhaled, and ocular administration. P&T committees, watch closely: Easier dosing could bring broader acceptance.

  1. New challenges and opportunities for industrial biotechnology

    OpenAIRE

    Chen Guo-Qiang

    2012-01-01

    Abstract Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate) and sand oil et al. The weaknesses of microbial or enzymatic processes compared with the chemical processing also make industrial biotech products less competitive with the chemical ones. However, many opportunities are still there if industrial biotech processes can be as similar as th...

  2. Norway – a global maritime knowledge hub

    OpenAIRE

    Reve, Torger

    2009-01-01

    Knowledge based industrial development takes place in Global Knowledge Hubs or superclusters characterized by a high concentration of innovative industrial actors interacting closely with advanced research institutions, venture capital and competent ownership. The extreme example of a global knowledge hub is the biotech and life science industry in Boston. The greater Boston area has a higher concentration of advanced universities, research labs and specialized biotech firms, than anywhere el...

  3. Channeling, Identity Preservation and the Value Chain: Lessons from the Recent Problems with Starlink Corn

    OpenAIRE

    Ginder, Roger

    2001-01-01

    Biotech grains hold great promise for both producers and consumers but a thorough understanding of the value chain will be vitally important in realizing that potential. Biotech grains with input traits not approved for all uses can pose a serious problem for the grain handling and processing industry as they move through the value chain. This problem occurs because there is no premium to cover added costs of segregation and handling input trait grains after harvest. In the case of Starlink t...

  4. Tissue Microarray A New Tool for Cancer Research

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Shanghai Outdo Biotech Co.Ltd. (Outdo Biotech) is a leading company in human/animal Tissue Microarrays (TMA) and "Clinical-Type" Gene Chip (CTGC) in China. Our shareholders are Shanghai Biochip Co., Ltd. & National Engineering Center for Biochip at Shanghai, Shanghai Cancer institute and Eastern Liver and Bladder Hospital of Second Military Medical University. TMA is a mean of combining tens to hundreds of specimens of tissue, paraffin embedded or frozen, onto a single slide for analysis at once. Our constr...

  5. The Relation between Moral and Legal Obligation: an Alternative Kantian Reading

    Czech Academy of Sciences Publication Activity Database

    Pavlakos, George

    Cambridge : Cambridge University Press, 2015 - (Pavlakos, G.; Rodriguez-Blanco, V.), s. 228-243 ISBN 978-1-107-07072-1 Institutional support: RVO:68378122 Keywords : moral obligation * legal obligation * philosophy of law Subject RIV: AG - Legal Sciences

  6. Emotional Experience and Religious Understanding: Integrating Perception, Conception and Feeling. [Reseña

    OpenAIRE

    Gallardo, F

    2008-01-01

    Reseña de Mark R. WYNN, Emotional Experience and Religious Understanding: Integrating Perception, Conception and Feeling, Cambridge University Press, Cambridge 2005, xiv+202 pp., 15 X 23, ISBN 0521549892.

  7. Psychology and Conservation Conflicts: Classified Bibliography of Special Topics

    OpenAIRE

    Blumberg, Herbert H.

    2013-01-01

    This document is ancillary to the following chapter but can also be used independently: Blumberg, Herbert H. (In press). Psychology and conflicts. In S. Redpath & J. C. Young (Eds.), Conservation conflicts. Cambridge, England: Cambridge University Press.

  8. Inverse problems in learning from data

    Czech Academy of Sciences Publication Activity Database

    Kůrková, Věra

    Cambridge: Cambridge Scientific Publishers, 2015 - (Kaslik, E.; Sivasundaram, S.), 2014 in print. (Mathematical Problems in Engineering Aerospace and Sciences. 6). ISBN 978-1-908106-16-2 Institutional support: RVO:67985807 Subject RIV: IN - Informatics, Computer Science

  9. Kant's Theory of virtue

    DEFF Research Database (Denmark)

    Nielsen, Carsten Fogh

    2012-01-01

    Anmeldelse af Anne Margaret Baxleys bog: "Kant's Thery of Virtue. The Value of Autocracy" (Cambridge University Press, 2010)......Anmeldelse af Anne Margaret Baxleys bog: "Kant's Thery of Virtue. The Value of Autocracy" (Cambridge University Press, 2010)...

  10. Effects of loud noise and loud music on brain activity in man

    Czech Academy of Sciences Publication Activity Database

    Syka, Josef; Tintěra, J.; Jilek, Milan

    Cambridge: NOPHER, 2000, s. 14. [An International Symposium on noise induced hearing loss. Cambridge (GB), 07.07.2000-10.07.2000] Institutional research plan: CEZ:AV0Z5039906 Subject RIV: FH - Neurology

  11. Cutting Back on Wine? Try a Smaller Glass

    Science.gov (United States)

    ... of Cambridge. In the study, Pechey's team tracked customers' purchases of wine in a restaurant/bar over ... a university news release. She works in Cambridge's Behavior and Health Research Unit. The findings suggest "that ...

  12. Living in the Multiverse

    OpenAIRE

    Weinberg, Steven

    2005-01-01

    This is the written version of the opening talk at the symposium "Expectations of a Final Theory," at Trinity College, Cambridge, on September 2, 2005. It is to be published in Universe or Multiverse?, ed. B. Carr (Cambridge University Press).

  13. Metapopulation dynamics in marine parasites

    Czech Academy of Sciences Publication Activity Database

    Pérez-del-Olmo, A.; Kostadinova, Aneta; Morand, S.

    Cambridge : Cambridge University Press, 2013, s. 35-48. ISBN 9781107019614 Institutional support: RVO:60077344 Keywords : metapopulation dynamics * marine parasites * human impact Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine

  14. A Ramesside Administrative Document

    DEFF Research Database (Denmark)

    Hagen, Frederik Norland

    2008-01-01

    Publikation av en ægyptisk administrativ papyrus fra Cambridge University Library, datert til c. 1100 f.Kr.......Publikation av en ægyptisk administrativ papyrus fra Cambridge University Library, datert til c. 1100 f.Kr....

  15. 77 FR 72840 - CE FLNG, LLC; Application for Long-Term Authorization To Export Liquefied Natural Gas Produced...

    Science.gov (United States)

    2012-12-06

    ... is owned by Cambridge Energy Group Limited. CE FLNG's affiliate Cambridge Energy, LLC is a marketer... other issues, including the impact on the U.S. economy (GDP), consumers, and industry, job creation,...

  16. Book Reviews

    OpenAIRE

    Redactie KITLV

    2003-01-01

    -Timothy Barnard, J.M. Gullick, A history of Selangor (1766-1939). Kuala Lumpur: Malaysian branch of the Royal Asiatic Society, 1989, vi + 220 pp. [MBRAS Monograph 28.] -Okke Braadbaart, Michael L. Ross, Timber booms and institutional breakdown in Southeast Asia. Cambridge: Cambridge University Press, 2001, xvi + 237 pp. -H.J.M. Claessen, Patrick Vinton Kirch ,Hawaiki, ancestral Polynesia; An essay in historical anthropology. Cambridge: Cambridge University Press, 2001, xvii + 375 pp., Roger ...

  17. Book Reviews

    OpenAIRE

    Redactie KITLV

    1993-01-01

    -Louis Allaire, Samuel M. Wilson, Hispaniola: Caribbean chiefdoms in the age of Columbus. Tuscaloosa: University of Alabama Press, 1990. xi + 170 pp. -Douglas Melvin Haynes, Philip D. Curtin, Death by migration: Europe's encounter with the tropical world in the nineteenth century. Cambridge: Cambridge University Press, 1989. xviii + 251 pp. -Dale Tomich, J.H. Galloway, The sugar cane industry: An historical geography from its origins to 1914. Cambridge: Cambridge University Press, 1989. xii +...

  18. Book Reviews

    OpenAIRE

    Niels Mulder; Kees Epskamp; K. Loven; David E.F. Henley; R. Z. Leirissa; Bernard Sellato; Han Knapen; Nico Schulte Nordholt; Victor T. King; Jan M. Pluvier; David Henley; Boomgaard, P.; Raymond L. Bryant; Daniel de Coppet; Coombs, H.C.

    1997-01-01

    - Peter Boomgaard, Robert L. Winzeler, Latah in Southeast Asia; The history and ethnography of a culture-bound syndrome. Cambridge: Cambridge University Press, 1995, xvi + 172 pp. [Publications of the Society for Psychological Anthropology 7.] - Ad Borsboom, H.C. Coombs, Aboriginal autonomy; Issues and strategies. Cambridge: Cambridge University Press, 1995, xvi + 251 pp. - Ad Borsboom, Daniel de Coppet, Cosmos and society in Oceania. Oxford: Berg, 1995, 416 pp. [Explorations in Anthropology ...

  19. Book Review: Training the Party: Party Adaptation and Elite Training in Reform-era China

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    2016-01-01

    Review of: Training the Party: Party Adaptation and Elite Training in Reform-era China. Charlotte P. Lee . Cambridge: Cambridge University Press, 2015. xii + 251 pp. $99.99. ISBN 978-1-107-09063-7......Review of: Training the Party: Party Adaptation and Elite Training in Reform-era China. Charlotte P. Lee . Cambridge: Cambridge University Press, 2015. xii + 251 pp. $99.99. ISBN 978-1-107-09063-7...

  20. Ateizm ve Din

    OpenAIRE

    ÜNAL, Yaşar; Martin, Michael

    2013-01-01

    The Cambridge Companion to ATHEISM, Edited by Michael Martin, Cambridge Collections Online ©Cambridge University Press, Printed in the United States of America, 2007, ss.217-232 içerisinde yer alan, “Atheism and Religion” isimli makaleden çevrilmiştir

  1. 3D Reconstruction in Magnetic Resonance Imaging

    Czech Academy of Sciences Publication Activity Database

    Mikulka, J.; Bartušek, Karel

    Cambridge : The Electromagnetics Academy, 2010, s. 1043-1046. ISBN 978-1-934142-14-1. [PIERS 2010 Cambridge. Cambridge (US), 05.07.2010-08.07.2010] R&D Projects: GA ČR GA102/09/0314 Institutional research plan: CEZ:AV0Z20650511 Keywords : 3D reconstruction * magnetic resonance imaging Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  2. Measuring strain and deflections of moving machine parts by a dual-system magnetoresistive sensor

    Czech Academy of Sciences Publication Activity Database

    Procházka, Pavel; Vaněk, František

    Cambridge: University of Cambridge, 2014. [International Conference on Experimental Mechanics /16./. 07.07.2014-11.07.2014, Cambridge] R&D Projects: GA TA ČR TA02020728 Institutional support: RVO:61388998 Keywords : turbine blade * vibration measurement * biaxial magnetoresistive sensor Subject RIV: BI - Acoustics

  3. Errors in Diffusion Coeffcients Measurement

    Czech Academy of Sciences Publication Activity Database

    Marcon, P.; Bartušek, Karel

    Cambridge : The Electromagnetics Academy, 2010, s. 1035-1039. ISBN 978-1-934142-14-1. [PIERS 2010 Cambridge. Cambridge (US), 05.07.2010-08.07.2010] Institutional research plan: CEZ:AV0Z20650511 Keywords : diffusion coefficient * MR imaging Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  4. Balloon Launched on Multiwall Carbon Nanotube Tether in Antarctica

    Czech Academy of Sciences Publication Activity Database

    Kletetschka, Günther; McKinney, E.; Kawasumiova, D.

    Cambridge: University of Cambridge, 2011. s. 1-1. [NT international Conference on the Science and Application of Nanotubes /11./. 10.07.2011-16.07.2011, Cambridge] Institutional research plan: CEZ:AV0Z30130516 Keywords : MWCNT * fibres * tether * strength * Antarctica Subject RIV: DB - Geology ; Mineralogy

  5. The Form, Mood and Musicality:A New Exploration of the Musicality of Saying Good-Bye to Cambridge Again%形式、意蕴与音乐性——《再别康桥》音乐性新探

    Institute of Scientific and Technical Information of China (English)

    李祖德

    2011-01-01

    从诗歌的情绪意蕴与形式的关系入手,分析一诗的旋律特征和旋律发展,以此探析该诗在音乐性上的独特性,并简要分析该诗形式与意蕴实现完美统一的奥秘.

  6. Promo BCA Treat A Friends “Buy One Get One Free” Terhadap Minat Beli Konsumen (Study Korelasional Hubungan Promo Kartu Kredit BCA Treat A Friends “Buy One Get One Free” terhadap minat beli konsumen Starbucks Coffee Cambridge City Square Medan)

    OpenAIRE

    Harahap, Rinaldy Effendy

    2012-01-01

    Penelitian ini berjudul Promo “BCA Treat A Friend Buy One Get One Free” dan minat beli. Beberapa teori komunikasi yang relevan dengan penelitian ini adalah Teori Komunikasi, Komunikasi Pemasaran dan Promosi Penjualan, Teori Minat Beli, Kartu Kredit dan Model AIDDA. Penelitian ini menggunakan metode korelasional dengan tujuan untuk meneliti sejauhmana variabel pada satu faktor berkaitan dengan variabel pada faktor yang lain. Variabel-variabel yang terdapat dalam penelitian ini adalah Promo kar...

  7. Benjamin A. Elman, On Their Own Terms: Science in China, 1550-1900. Cambridge,MA: Harvard University Press, 2005, xxxviii + 567pp%本杰明·艾尔曼著《以他们自己的方式:科学在中国,1550-1900》

    Institute of Scientific and Technical Information of China (English)

    原祖杰

    2006-01-01

    @@ 普林斯顿大学历史学教授本杰明·艾尔曼的新书(该书将由国家清史编委会翻译出版),是继其多部在中国思想史领域富有影响的著作之后的又一引人注目的学术成果.他在本书的序言中写道:"19世纪中叶以来的中国历史有一种一贯性,那就是无论帝制时期的改革者,还是早期的共和派,无论国民党官员,还是中国共产党人,都一如既往地重视科学技术."(p.xxxi)但他认为,尽管有李约瑟等人的重要贡献,我们对1900年以前中国自然研究的了解仍处于模糊状态.该书概述了16世纪至20世纪初耶稣会和基督教传教士影响下的本土中国科学的演变,其结论是"中国人创造了他们自己的科学."

  8. Arthur. Waldron From War to Nationalism: China's Turning, Point,1924-1925 Cambridge University Press, 1995,366p.%林霨著《从站争到民族主义:中国的转折点,1924-1925》

    Institute of Scientific and Technical Information of China (English)

    马敏

    2002-01-01

    @@ 在以往北洋军阀史研究中,1924年的直奉战争并不摆在十分重要的地位,多被视为无数次军阀混战中的一次而已;另一方面,论及20年代的剧烈政治变动,人们注目的又往往是五(一川)运动、北伐站争、民族主义、国民革命等史诗般的宏大政治叙事.而在战争硝烟与民族主义浪潮之间、在制度性崩解与国民革命的兴起之间,究竟存不存在革种历史的内在联系?在务种推动历史前进的动力之中,战争究竟扮演着什么样的历史角色?从既有的关于民国历史、关于中国大革命史的规范性历史言说中,是否还能有另一种诠释?另一路不蹈常习故的思考?这些,便是林霨新著试图回答的问题与论述中心.

  9. The Role of Transgenic Crops in the Future of Global Food and Feed

    Directory of Open Access Journals (Sweden)

    O. Škubna

    2012-06-01

    Full Text Available The paper is aimed on the problematic of biotech crops planting (GM, transgenic crops. The main aim of this paper is to analyze the trends in the main biotech crops planting groups in the sense of their use for food and feed in the future. The selected groups of biotech crops analyzed in this article are soybeans, maize (corn, cotton and rapeseed (canola. The used methods are chain and basic indexes and regression analysis of times series/ trend data - for predicting on next four years (2012-2015. The trends are able to determine the necessity of implementation the biotech crops planting into the agricultural systems everywhere (also in EU and it is without the questions if the impact are mainly positive or negative. The dependence of world agricultural commodity market on the biotech crops is undeniable and the prediction acknowledges that the importance is increasing. Pieces of knowledge introduced in this paper resulted from solution of an institutional research intention MSM 6046070906 „Economics of resources of Czech agriculture and their efficient use in frame of multifunctional agri-food systems“.

  10. Patent holdings of US biotherapeutic companies in major markets.

    Science.gov (United States)

    Sebastian, Teena E; Yerram, Chandra Bindu; Saberwal, Gayatri

    2009-05-01

    In previous studies we examined the (United States, US) patent holdings of 109 largely North American biotech companies developing therapeutics that, in particular, have an interest in discovery stage science. There appears little correlation between the number of patents and the number of products of individual companies. Here we quantified and compared the 103 US-headquartered companies' patent holdings in Australia, Canada, Europe, Japan and the US. The companies demonstrate variable and surprising patterns of patent holdings across these countries or regions. For most companies, patent holdings are not in proportion to the importance of the country as a biotech or pharma market. These results have implications for the patenting strategies of small biotech companies involved in drug discovery. PMID:19429502

  11. Research Strategies in Science-based Start-ups

    DEFF Research Database (Denmark)

    Valentin, Finn; Dahlgren, Johan Henrich; Lund Jensen, Rasmus

    Although biotech start-ups fail or succeed based on their research few attempts have been made to examine if and how they strategize in this core of their activity. Popular views on Dedicated Biotech Firms (DBFs) see the inherent uncertainty of research as defying notions of strategizing, directing...... instead the attention to the quality of their science, or the roles of boards, management, and collaborative networks etc. Using a unique comprehensive dataset on Danish and Swedish biotech start-ups in drug discovery this paper analyzes their research strategies. Adopting a Simonean point of departure we...... Shonhoovens classical argument that "strategy matters" is valid not only for the larger high-tech firms covered by her study, but also for small research-based start-ups operating at the very well springs of knowledge where science directly interacts with technologies. Even though a lot more research is...

  12. Beyond the Boundary

    DEFF Research Database (Denmark)

    Gorm Hansen, Birgitte

    2012-01-01

    . Drawing on interviews with the head of a research center in plant biology, this article argues that biology and biotech are symbionts. In order to be viable and productive, symbiosis needs to be carefully managed and given room for divergence within mutual dependence. This process does not take place as...... the negotiation of a preexisting science-industry boundary. Rather, viability is obtained through a strategy of circumventing the science-industry food chain and sequestering biotech components within the research center. Symbiosis allows academic scientists to do biology while at the same time...

  13. Beyond the Boundary

    DEFF Research Database (Denmark)

    Gorm Hansen, Birgitte

    2011-01-01

    . Drawing on interviews with the head of a research center in plant biology, this article argues that biology and biotech are "symbionts". In order to be viable and productive, symbiosis needs to be carefully managed and given room for divergence within mutual dependence. This process does not take place as...... the negotiation of a preexisting science-industry boundary. Rather, viability is obtained through a strategy of "circumventing" the science-industry food chain and "sequestering" biotech components within the research center. Symbiosis allows academic scientists to do biology while at the same time...

  14. Bioprocessing of wheat straw into nutritionally rich and digested cattle feed

    OpenAIRE

    Shrivastava, Bhuvnesh; Jain, Kavish Kumar; Kalra, Anup; Kuhad, Ramesh Chander

    2014-01-01

    Wheat straw was fermented by Crinipellis sp. RCK-1, a lignin degrading fungus, under solid state fermentation conditions. The fungus degraded 18.38% lignin at the expense of 10.37% cellulose within 9 days. However, when wheat straw fermented for different duration was evaluated in vitro, the 5 day fungal fermented wheat straw called here “Biotech Feed” was found to possess 36.74% organic matter digestibility (OMD) and 5.38 (MJ/Kg Dry matter) metabolizable energy (ME). The Biotech Feed was als...

  15. Science communication in policy making

    DEFF Research Database (Denmark)

    Coumou, Hilde; van der Werf Kulichova, Z.; Wehrmann, C.;

    2014-01-01

    Policy making regarding application of agricultural biotechnology has been controversial. This study investigates what determines the motivation of European biotech scientists to actively participate in policy making. To do this, a conceptual framework was developed based on the Theory of Planned...... Behavior. The framework was operationalized in semi-structured interviews with 17 European biotech scientists to collect data about their motivation to involve in GMO policy making. The results of this qualitative study suggest that the attitude of the scientists towards active participation in policy...

  16. Barriers to health care for undocumented immigrants: a literature review

    OpenAIRE

    Hacker K; Anies M; Folb BL; Zallman L

    2015-01-01

    Karen Hacker,1,2 Maria Anies,2 Barbara L Folb,2,3 Leah Zallman4–6 1Allegheny County Health Department, Pittsburgh, PA, USA; 2Graduate School of Public Health, 3Health Sciences Library System, University of Pittsburgh, Pittsburgh, PA, USA; 4Institute for Community Health, Cambridge, MA, USA; 5Cambridge Health Alliance, Cambridge, MA, USA; 6Harvard School of Medicine, Boston, MA, USA Abstract: With the unprecedented international migration seen in recent years, policies that limit he...

  17. On the World Wide Web: Cost Effective Solutions to Database Searching

    OpenAIRE

    Decastro, Bart

    2012-01-01

    In a recent questionnaire survey of Cambridge Scientific subscribers, over 90% expressed preference for the delivery of abstracting/indexing services through the Internet. This fact has been the rationale for Cambridge Scientific's Internet initiative. Thirty-six of Cambridge Scientific's databases, previously available in print and CD-ROM, are now searchable through the World Wide Web. More recently, these databases have been clustered into eight sets, each with a unified index, covering cri...

  18. Polarization of thermal emission from accreting black holes

    Czech Academy of Sciences Publication Activity Database

    Dovčiak, Michal; Karas, Vladimír; Goosmann, René; Matt, G.; Muleri, F.

    Cambridge: Cambridge University Press, 2010 - (Bellazzini, R.; Costa, E.; Matt, G.; Tagliaferi, G.), s. 117-121. (Cambridge Contemporary Astrophysics). ISBN 978-0-521-19184-5. [Coming age of X-ray polarimetry. Rome (IT), 27.04.2009-30.04.2009] Grant ostatní: ESA(XE) ESA-PECS project No. 98040 Institutional research plan: CEZ:AV0Z10030501 Keywords : Astrophysics * Polarimetry * X-rays Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  19. Towards Bayesian filtering on restricted support

    Czech Academy of Sciences Publication Activity Database

    Pavelková, Lenka; Kárný, Miroslav; Šmídl, Václav

    Cambridge : University of Cambridge, 2006, s. 1-4. ISBN 978-1-4244-0579-4. [Nonlinear Statistical Siganl Processing Workshop 2006. Cambridge (GB), 13.09.2006-15.09.2006] R&D Projects: GA MŠk 1M0572; GA AV ČR 1ET100750401; GA MŠk 2C06001 Institutional research plan: CEZ:AV0Z10750506 Keywords : bayesian estimation * state model * restricted support Subject RIV: BC - Control Systems Theory

  20. Round table

    DEFF Research Database (Denmark)

    Jensen, Tine Wirenfeldt

    in Academia . Qualitative Research 7(4):pp. 459-473. Holstein & Gubrium, 1995, The active Interview, Qualitative Research Method Series 37, Sage. Leech, B., 2002. “Asking Questions: Techniques for Semistructured Interviews” in Leech B. et al. ”Symposium: Interview Methods” in Political Science and...... Politics, Vol 35, no. 4, Cambridge University Press, Cambridge Journals. Aberback J. & Rockman B, 2002. “Conducting and Coding Elite Interviews” in Leech B. et al. ”Symposium: Interview Methods” in Political Science and Politics, Vol 35, no. 4, Cambridge University Press, Cambridge Journals....

  1. The Controversies over Bioenergy in Denmark

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Andersen, Bente Hessellund

    2012-01-01

    convert coal fired power plants to biomass in order to sustain the role of these power plants. Their increasing use of imported wood pellets is criticized for increasing greenhouse gas emissions because of fast logging of years of forest growth. A Danish biotech company is developing enzymes for...

  2. DTREEv2, a computer-based support system for the risk assessment of genetically modified plants

    NARCIS (Netherlands)

    Pertry, I.; Nothegger, C.; Sweet, J.; Kuiper, H.A.; Davies, H.; Iserentant, D.; Hull, R.; Mezzetti, B.; Messens, K.; Loose, De M.; Oliveira, de D.; Burssens, S.; Gheysen, G.; Tzotzos, G.

    2014-01-01

    Risk assessment of genetically modified organisms (GMOs) remains a contentious area and a major factor influencing the adoption of agricultural biotech. Methodologically, in many countries, risk assessment is conducted by expert committees with little or no recourse to databases and expert systems t

  3. The Provincial Capital's Future

    Institute of Scientific and Technical Information of China (English)

    DING WENLEI

    2010-01-01

    @@ A new city is in the making on the eastern outskirts of Guangzhou.In lieu of the average citizen,the city will be home to thousands of biotech engineers or new energy researchers.It will be a green city.It will be a hi-tech city.It will be a city of the future.

  4. Experiment list: SRX142525 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Cruz Biotech || antibody vendorid=sc-197 || control=Control_50bp || control description=This data represents a control being compare...on=Immortal cells || control=Control_50bp || control description=This data represents a control being compare

  5. Biotechnology Education in India: An Overview

    Science.gov (United States)

    Joshi, Kirti; Mehra, Kavita; Govil, Suman; Singh, Nitu

    2013-01-01

    Among the developing countries, India is one of those that recognises the importance of biotechnology. The trajectory of different policies being formulated over time is proof that the government is progressing towards achieving self-sufficiency. However, to cater to the ever-growing biotech industry, skilled manpower is required. This article…

  6. Networked Success and Failure at Hybritech

    Science.gov (United States)

    Jones, Mark Peter

    2011-01-01

    The author presents an historical account of scientific work conducted at a commercial biotech firm in San Diego called Hybritech. It tells of disruptions in research programs following the acquisition of the company by the pharmaceutical giant Eli Lilly in 1986. The story centers on responses to an organizational challenge that research managers…

  7. Global scenario on crop biotechnology: Communication setting

    Science.gov (United States)

    Various indications that research and development efforts are escalating in developing countries indicate the slight shift of such countries from just being end markets to being developers. The aggregate adoption of biotech crops in developing countries is clearly approaching that in developed count...

  8. Ryntäys Viroon jatkuu / Eeva-Riitta Seies

    Index Scriptorium Estoniae

    Seies, Eeva-Riitta

    2002-01-01

    Soome kontsern Vapo ostis ASi Tootsi Turvas enamusaktsiad. Soome ettevõte Fit Biotech ostis Tartu biotehnoloogiaettevõtte Quattromed ja Soome toiduainetetööstuse ettevõte Saarioinen Oy Eesti tütarfirma omandas üle 66-protsendilise osaluse valmistoidufirmas Meleco AS

  9. Public perceptions of farm animal cloning in Europe

    OpenAIRE

    Lassen, Jesper

    2005-01-01

    This report presents a picture of European opinion on farm animal cloning. In the report, both agricultural and biomedical applications of farm animal cloning are considered. With the arrival of Dolly, animal cloning became an integral part of the biotech debate, but this debate did not isolate animal cloning as a single issue.

  10. Innnovation and new business models for the regional development: travel and transportation

    OpenAIRE

    Tafur Segura, José Javier

    2011-01-01

    Regional development could present different strategies: •Relocation of industry clusters •Foreign Direct Investment attraction •Innovation based on new business models The Regional Government of Madrid (3rd largest GDP in the EU) selected strategic industries to compete & innovate: •Travel & Transportation •Aerospace •Nanotech. & •Biotech. •ICTs. •Energy

  11. Public perceptions of farm animal cloning in Europe

    DEFF Research Database (Denmark)

    Lassen, Jesper

    This report presents a picture of European opinion on farm animal cloning. In the report, both agricultural and biomedical applications of farm animal cloning are considered. With the arrival of Dolly, animal cloning became an integral part of the biotech debate, but this debate did not isolate...... animal cloning as a single issue....

  12. Experiment list: SRX821798 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available riment type=PPARG ChIP-seq || strain=N/A || tissue=NA || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotech...nologies http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/

  13. New insights on the relationships between geographic and institutional distance in research collaborations: a long period analysis

    OpenAIRE

    D'Amore, Rosamaria; Iorio, Roberto

    2014-01-01

    This paper analyses the relationship between institutional and geographic distance in scientific collaborations, evaluating the possible changes when a long period (sixteen years) is taken into consideration and discussing the use of some alternative measures of institutional distance. The main result, obtained by analysing the publications of the Italian biotech firms, is that international publications present an higher institutional distance than national papers, particularl...

  14. The integrated web service and genome database for agricultural plants with biotechnology information

    OpenAIRE

    Kim, ChangKug; Park, DongSuk; Seol, YoungJoo; Hahn, JangHo

    2011-01-01

    The National Agricultural Biotechnology Information Center (NABIC) constructed an agricultural biology-based infrastructure and developed a Web based relational database for agricultural plants with biotechnology information. The NABIC has concentrated on functional genomics of major agricultural plants, building an integrated biotechnology database for agro-biotech information that focuses on genomics of major agricultural resources. This genome database provides annotated genome information...

  15. Reporter-based screening and selection of enzymes

    NARCIS (Netherlands)

    Rossum, van T.; Kengen, S.W.M.; Oost, van der J.

    2013-01-01

    The biotech industry is continuously seeking for new or improved biocatalysts. The success of these efforts is often hampered by the lack of an efficient screening assay. Thus, to be able to extend the number of enzymes available for industrial applications, high-throughput screening and selection m

  16. Molecular characteristics and efficacy of 16D10 siRNAs in inhibiting root-knot nematode infection in transgenic grape hairy roots

    Science.gov (United States)

    Root-knot nematodes (RKNs) infect many annual and perennial crops and are the most devastating soil-born pests in vineyards. To develop a biotech-based solution for controlling RKNs in grapes, we evaluated the efficacy of plant-derived RNA interference (RNAi) silencing of a conserved RKN effector ge...

  17. The waves of Biotechnological Innovation in Medicine: Interfirm Cooperation Effects and a Venture Capital Perspective

    OpenAIRE

    Fernald, Kenneth

    2015-01-01

    markdownabstractAbstract Improving medicine and health is the ultimate purpose of biotechnological innovation, where basic science is used to develop new innovative diagnostics and therapeutics to significantly improve the lives of patients worldwide. Concurrently, for three stakeholder groups, the primary goal is to generate profitable business from biotechnological innovation. These stakeholders are ‘entrepreneurial’ biotech companies, venture capitalists and established pharmaceutical firm...

  18. Social Capital, ICT Use and Company Performance

    DEFF Research Database (Denmark)

    Scupola, Ada; Steinfield, Charles; Lopez-Nicolas, Carolina

    2010-01-01

    This study explores how some uses of ICTs, as well as having social capital and other means of access to knowledge resources, are related to company performance in a knowledge-intensive business cluster. Data were collected through a survey of companies in the Medicon Valley biotech region locate...

  19. Bioprocessing of wheat straw into nutritionally rich and digested cattle feed.

    Science.gov (United States)

    Shrivastava, Bhuvnesh; Jain, Kavish Kumar; Kalra, Anup; Kuhad, Ramesh Chander

    2014-01-01

    Wheat straw was fermented by Crinipellis sp. RCK-1, a lignin degrading fungus, under solid state fermentation conditions. The fungus degraded 18.38% lignin at the expense of 10.37% cellulose within 9 days. However, when wheat straw fermented for different duration was evaluated in vitro, the 5 day fungal fermented wheat straw called here "Biotech Feed" was found to possess 36.74% organic matter digestibility (OMD) and 5.38 (MJ/Kg Dry matter) metabolizable energy (ME). The Biotech Feed was also observed to be significantly enriched with essential amino acids and fungal protein by fungal fermentation, eventually increasing its nutritional value. The Biotech Feed upon in vitro analysis showed potential to replace 50% grain from concentrate mixture. Further, the calves fed on Biotech Feed based diets exhibited significantly higher (p<0.05) dry matter intake (DMI: 3.74 Kg/d), dry matter digestibility (DMD: 57.82%), total digestible nutrients (TDN: 54.76%) and comparatively gained 50 g more daily body weight. PMID:25269679

  20. Kernel compositions of glyphosate-tolerant and corn rootworm-protected MON 88017 sweet corn and insect-protected MON 89034 sweet corn are equivalent to that of conventional sweet corn (Zea mays).

    Science.gov (United States)

    Curran, Kassie L; Festa, Adam R; Goddard, Scott D; Harrigan, George G; Taylor, Mary L

    2015-03-25

    Monsanto Co. has developed two sweet corn hybrids, MON 88017 and MON 89034, that contain biotechnology-derived (biotech) traits designed to enhance sustainability and improve agronomic practices. MON 88017 confers benefits of glyphosate tolerance and protection against corn rootworm. MON 89034 provides protection against European corn borer and other lepidopteran insect pests. The purpose of this assessment was to compare the kernel compositions of MON 88017 and MON 89034 sweet corn with that of a conventional control that has a genetic background similar to the biotech sweet corn but does not express the biotechnology-derived traits. The sweet corn samples were grown at five replicated sites in the United States during the 2010 growing season and the conventional hybrid and 17 reference hybrids were grown concurrently to provide an estimate of natural variability for all assessed components. The compositional analysis included proximates, fibers, amino acids, sugars, vitamins, minerals, and selected metabolites. Results highlighted that MON 88017 and MON 89034 sweet corns were compositionally equivalent to the conventional control and that levels of the components essential to the desired properties of sweet corn, such as sugars and vitamins, were more affected by growing environment than the biotech traits. In summary, the benefits of biotech traits can be incorporated into sweet corn with no adverse effects on nutritional quality. PMID:25764285

  1. CCACB - Culture Collection of Actinomycetes of the Institute of Soil Biology České Budějovice, Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Krištůfek, Václav; Chroňáková, Alica; Petrásek, Jiří; Chrudimský, Tomáš; Elhottová, Dana

    Praha: Institute of Chemical Technology Prague, 2014. s. 157-158. ISBN 978-80-7080-887-0. [BioTech 2014 & 6 th Czech-Swiss Symposium with Exhibition. 11.06.2014-14.06.2014, Praha] Institutional support: RVO:60077344 Keywords : CCACB * soil actinomycetes * depository Subject RIV: EE - Microbiology, Virology

  2. TECHcitement: Advances in Technological Education, 2004

    Science.gov (United States)

    American Association of Community Colleges (NJ1), 2004

    2004-01-01

    This edition of "TECHcitement" contains the following articles: (1) ATE Program Leads to Student Success; (2) Doing Whatever It Takes for Aquaculture; (3) The Bridge to Biotech; (4) Girls See What They Can Do With Technology at Camp; (5) Students Advancing Solutions to Business Problems; (6) CREATE Recreates Technical Education in California; (7)…

  3. Genome sequence and annotation of Streptomyces sp. W6 - putative natural producer of annimycin antibiotic

    Czech Academy of Sciences Publication Activity Database

    Chrudimský, Tomáš; Chroňáková, Alica; Petříčková, Kateřina; Petříček, Miroslav; Krištůfek, Václav

    Praha : Institute of Chemical Technology Prague, 2014. s. 102-103. ISBN 978-80-7080-887-0. [BioTech 2014 & 6 th Czech-Swiss Symposium with Exhibition. 11.06.2014-14.06.2014, Praha] Institutional support: RVO:60077344 ; RVO:61388971 Keywords : genome sequence * annotation * Streptomyces sp. W6 * annimycin antibiotic Subject RIV: EE - Microbiology, Virology

  4. 75 FR 71078 - Citric Acid and Certain Citrate Salts From People's Republic of China: Partial Rescission of...

    Science.gov (United States)

    2010-11-22

    ... Request Administrative Review, 75 FR 23236-37 (May 3, 2010). On June 1, 2010, in accordance with 19 CFR... Countervailing Duty Administrative Reviews and Requests for Revocation in Part, 75 FR 37759 (June 30, 2010). On... Group Co., Ltd. Shanghai Henglijie Bio-Tech Co., Ltd. Shanghai Fenhe Biochemical Co., Ltd. Shanxi...

  5. Akadeemikust ettevõtja võitleb viirustega / Kaire Talviste

    Index Scriptorium Estoniae

    Talviste, Kaire, 1979-

    2012-01-01

    Molekulaarbioloog Mart Ustavi tööst bioloogiliste ravimite väljatöötamisel. HIV1/AIDS vaktsiini väljatöötamisest FIT Biotech Oy Eesti filiaalis a-tel 2000-2011. M. Ustavi biotehnoloogia firma Icosagen Grupp tehnoloogilistest arendustest

  6. Eesti HIVi alatüüp jõuab registrisse / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2005-01-01

    Ülemaailmses HIV- andmebaasis on registreerimisel HI-viiruse alatüüp, mida on seni avastatud ainult Eestis. Mosaiik-HIV on segu peamiselt Aafrikas esinevast viiruse vormist ning Ukrainas levinud tüübist, selgub biotehnoloogiafirma FIT Biotech uuringust. Kommenteerib Tartu Ülikooli tehnoloogiainstituudi direktor Mart Ustav

  7. Making the Case to Managed Care: The Science of Marketing Biologics

    OpenAIRE

    APPLEBY, CHUCK

    2004-01-01

    Making a case when biotechs market their products to their most cost-conscious customers — managed care organizations — is far different than what a traditional pharmaceutical company might do with HMO partners. It’s all about the science. Not the cost.

  8. Preliminary format design guidelines

    DEFF Research Database (Denmark)

    Tosello, Guido; Calaon, Matteo; Nørregaard, J.;

    2013-01-01

    The strategic research centre PolyNano aims at becoming the Danish competence centre for production-ready fabrication of polymer, nano-scale lab-on-a-chip (LoC) devices. In order to provide a competitive edge for Danish biotech companies launching LoC products by removal of the technology barrier...

  9. Experiment list: SRX262791 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea...IH3T3_MRTFB_LAT || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-B || chip antibody vendor=Santa Cruz Biotech

  10. The Rhetorical Helix of the Biotechnology and Pharmaceutical Industries: Strategies of Transformation through Definition, Description and Ingratiation

    Science.gov (United States)

    Gretton, Linda Burak

    2009-01-01

    The current pharmaceutical industry, whose origins date from the early 20th century, and the biotechnology industry, which emerged in the 1980s both have foundations built on the modern scientific method and share a mission to develop new drugs for humans and animals. At the same time, they are also made distinct by size (small biotechs versus…

  11. Experiment list: SRX262787 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available IH3T3_MRTFA_LAT || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-A || chip antibody vendor=Santa Cruz Biotech...nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea

  12. Pharmaceutical Economics

    OpenAIRE

    2008-01-01

    Pharmaceutical Economics begins with an investigation of the structure of the industry and its three main components: the research firms which produce innovative products; the generic drug industry and its expanding role; and the biotech industry, which is regarded as the future for pharmaceuticals. Further sections discuss topics including demand and incentives, pricing and regulation.

  13. Informational Environments: Organizational Contexts of Online Information Use.

    Science.gov (United States)

    Lamb, Roberta; King, John Leslie; Kling, Rob

    2003-01-01

    Examines sustained use and non-use of online services within organizations using an open-systems view that overcomes limitations of traditional approaches that led to over-estimates of use. Focuses on the informational environments of firms in three industries: law, real estate, and biotech/pharmaceuticals; and discusses insights from an intranets…

  14. Do-it-yourself biology

    NARCIS (Netherlands)

    Golinelli, Stefano; Ruivenkamp, Guido

    2016-01-01

    Do-it-yourself biology, or garage biology, is a set of practices through which lay people can practice biotechnology and thus also challenge the exclusive control exercised on biotech R&D by Big Bio. This article describes how garage biologists aim to radically transform biotechnological soci

  15. Eesti firma hakkab koostöös soomlastega välja töötama Ebola viiruse ravimit / Joosep Värk

    Index Scriptorium Estoniae

    Värk, Joosep

    2014-01-01

    Eesti biotehnoloogiafirma Icosagen hakkab koos Soome ettevõtte FIT Biotech Oy'ga välja töötama Ebola viiruse vastast vaktsiini, arendustöös osaleb professor Andres Meritsa juhtimisel ka Tartu Ülikooli Tehnoloogiainstituudi rakendusviroloogia labor. Vestlusest Tartu Ülikooli biomeditsiinitehnoloogia professori Mart Ustaviga

  16. Tartu teadlased aitavad välja mõelda Ebola-vastast vaktsiini / Aime Jõgi

    Index Scriptorium Estoniae

    Jõgi, Aime, 1958-

    2014-01-01

    Eesti biotehnoloogiafirma Icosagen hakkab koos Soome ettevõtte FIT Biotech Oy'ga välja töötama Ebola viiruse vastast vaktsiini, arendustöös osaleb ka Tartu Ülikooli Tehnoloogiainstituudi rakendusviroloogia labor

  17. Technology and international strategies in born global firms: evidence from The Netherlands

    NARCIS (Netherlands)

    Kundu, Sumit; Roelfsema, Hein; Delft, Anne van

    2010-01-01

    This paper analyzes the internationalization strategies of biotech firms in the Netherlands. We find that many of these firms are born internationals in the sense that from their inception they are actively engaged in international cooperation. However, we find that the nature of potential intellect

  18. How to get exogenous DNA to cross the cell membrane of plants. Comment on “Physical methods for genetic transformation in plants” by Rivera et al.

    Science.gov (United States)

    Cruz Hernández, Andrés; Campos Guillén, Juan

    2012-09-01

    Physical methods for genetic transformation in plants. The most commonly applied methods in plant transformation include Agrobacterium infection and protoplast or microprojectile bombardment. A plant transformation system is a prerequisite for the development of a plant improvement program. The global area utilized for biotech crops increases every year.

  19. Uninformed and disinformed society and the GMO market.

    Science.gov (United States)

    Twardowski, Tomasz; Małyska, Aleksandra

    2015-01-01

    The EU has a complicated regulatory framework, and this is slowing down the approval process of new genetically modified (GM) crops. Currently, labeling of GM organisms (GMOs) is mandatory in all Member States. However, the USA, in which GMO labeling is not mandatory, continues to lead the production of biotech crops, biopharmaceuticals, biomaterials, and bioenergy. PMID:25528967

  20. Identification and characterisation of probiotic lactic acid bacteria

    Czech Academy of Sciences Publication Activity Database

    Španová, A.; Rittich, B.; Horák, Daniel; Dráb, V.; Drbohlav, J.

    Hydebarad : Osmania University, 2008. s. 17. [International Congress on Bioprocesses in Food Industries /3./ & Convention of the Biotech Research Society India /5./. 06.11.2008-08.11.2008, Hyderabad] Institutional research plan: CEZ:AV0Z40500505 Keywords : probiotic lactic acid bacteria Subject RIV: CE - Biochemistry

  1. Final Report: Northern Virginia Community College Training for Biotechnology Workers

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, Johanna V

    2010-05-31

    The intent of this project was to expand Northern Virginia Community College's capability to offer training to support the Biotechnology Industry in the northern Virginia region. The general goal of this project was to create a College Biotechnology Program; specific goals of the project were to a) design curricula/courses to prepare students to become entry-level lab technicians, b) redesign and equip lab space to better suit the needs of the program, c) develop partnerships with the local industry through outreach and the formation on an advisory board, d) recruit students into the program, and e) provide instructional support for local high school teachers. At the end of the grant period, NOVA has successfully created two new curricula in biotechnology: an Associate of Applied Science (A.A.S.) in Biotechnology (initiated in Fall 2008) and a Career Studies Certificate for Biotechnology Lab Technicians (to be initiated in Fall 2010). These curricula were designed with advice from an external advisory committee which is comprised of representatives from industry, transfer institutions and high school administrators. To date, almost all courses have been designed and piloted; the equipment needed for the courses and the initial supplies were paid for by the grant as was the re-modeling of some lab space to be used for the biotech courses. In order to market the program, the NOVA Biotech Program has also established relationships with the local high schools. Presentations were given at several local high schools and on-site workshops were held for high school students and teachers. As a result, close to 1000 students have attended program open houses, presentations within the high schools, or workshops held in the summer. Over 100 teachers have received information and/or training in biotechnology. These outreach efforts as well as high quality curricula have started to attract a number of students to the program – for example, there are currently 70 students

  2. The Measurement of Temperature Characteristics of Cu Bulk Resistivity

    Czech Academy of Sciences Publication Activity Database

    Bartušek, Karel; Fiala, P.; Dohnal, P.

    Cambridge : The Electromagnetics Academy, 2008, s. 827-831. ISBN 978-1-934142-06-6. ISSN 1559-9450. [Progress In Electromagnetics Research Symposium - PIERS 2008. Cambridge (GB), 02.07.2008-06.07.2008] Institutional research plan: CEZ:AV0Z20650511 Keywords : resistivity * temperature dependence of resistivity * Kelvins probe * cryotechnics Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  3. Spilteorien og (et par af) dens fædre

    DEFF Research Database (Denmark)

    Hansen, Sune Welling

    2011-01-01

    Boganmeldelse af Robert Leonard's "Von Neumann, Morgenstern, and the Creation of Game Theory: From Chess to Social Science, 1900-1960". Cambridge University Press.......Boganmeldelse af Robert Leonard's "Von Neumann, Morgenstern, and the Creation of Game Theory: From Chess to Social Science, 1900-1960". Cambridge University Press....

  4. The normative dimension of discourse

    Czech Academy of Sciences Publication Activity Database

    Peregrin, Jaroslav

    Cambridge : Cambridge University Press, 2012 - (Allan, K.; Jaszczolt, K.), s. 209-225 ISBN 978-0-521-19207-1 R&D Projects: GA ČR(CZ) GAP401/10/0146 Institutional research plan: CEZ:AV0Z90090514 Institutional support: RVO:67985955 Keywords : speech acts * normativity * pragmatism * normative pragmatics Subject RIV: AA - Philosophy ; Religion

  5. Commission 20: Positions and Motions of Minor Planets, Comets and Satellites

    Czech Academy of Sciences Publication Activity Database

    Fernandez, J. A.; Yoshikawa, M.; Valsecchi, G. B.; Chesley, S.; Chernetenko, Y.; Gilmore, A.; Lazzaro, D.; Muinonen, K.; Pravec, Petr; Spahr, T. B.; Tholen, D.; Tichá, J.; Zhu, J.

    Cambridge : Cambridge University Press, 2010 - (Corbett, I.), s. 175-176 ISBN 978-0-521-76831-3. - (Proceedings of the International Astronomical Union. IAU Transactions. 27B) Institutional research plan: CEZ:AV0Z10030501 Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  6. Regional-scale modeling of greenhouse gas fluxes

    Czech Academy of Sciences Publication Activity Database

    Juruš, Pavel; Musílek, P.; Li, Y.; Rodway, J.

    Cambridge: Cambridge University Press, 2012 - (Vitt, D.; Bhatti, J.), s. 23-55 ISBN 978-1-107-01571-5 Institutional research plan: CEZ:AV0Z10300504 Keywords : CO2 modelling * carbon cycle * boreal forest Subject RIV: DG - Athmosphere Sciences, Meteorology

  7. Extracellular space diffusion parameters in the frog spinal cord and filum terminale: Effect of elevated potassium and hypotonic stress

    Czech Academy of Sciences Publication Activity Database

    Prokopová, Šárka; Šimonová, Zuzana; Syková, Eva

    Cambridge : Cambridge University Press, 1998. s. 15P. ISSN 0022-3751. [Joint Meeting with the Czech Physiological Society. 22.06.1998-24.06.1998, Praha] R&D Projects: GA ČR GV309/97/K048; GA MZd IZ3423

  8. V379 Cep: A Quadruple System of Two Binaries

    Czech Academy of Sciences Publication Activity Database

    Harmanec, P.; Mayer, P.; Božic, H.; Eenens, P.; Guinan, E. F.; Guinan, E. F.; McCook, G.; Koubský, Pavel; Ruždjak, D.; Sudar, D.; Šlechta, Miroslav; Wolf, M.; Yang, S.

    Cambridge : Cambridge University Press, 2007 - (Hartkopf, W.; Guinan, E.; Harmanec, P.). s. 64 ISBN 978-0-521-86348-3. ISSN 1743-9213. [Symposium of the International Astronomical Union /240./. 22.08.2006-25.08.2006, Praha] Institutional research plan: CEZ:AV0Z10030501 Keywords : V379 Cep * quadruple systems

  9. Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntingtons disease

    DEFF Research Database (Denmark)

    Wyttenbach, A.; Swartz, J.; Kita, H.;

    2001-01-01

    Wellcome Trust Centre for Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK, 1Taisho Laboratory of Functional Genomics, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma...

  10. Commission 22: Meteors, Meteorites and Interplanetary Dust

    Czech Academy of Sciences Publication Activity Database

    Watanabe, J.; Jenniskens, P.; Spurný, Pavel; Borovička, Jiří; Campbell-Brown, M.; Consolmagno, G.; Jopek, T.; Vaubaillon, J.; Williams, I.P.; Zhu, J.

    Cambridge: Cambridge University Press, 2010 - (Corbett, I.), s. 177-179. (Proceedings of the International Astronomical Union. IAU Transactions. 27B). ISBN 978-0-521-76831-3 Institutional research plan: CEZ:AV0Z10030501 Keywords : meteors * meteorites * interplanetary dust Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  11. Temperature Induced Changes of Spontaneous Photon Emission from Human Hands

    Czech Academy of Sciences Publication Activity Database

    Cifra, Michal; Van Wijk, E.; Van Wijk, R.

    Cambridge : The Electromagnetics Academy, 2008, s. 907-911. ISBN 978-1-934142-06-6. ISSN 1559-9450. [Progress In Electromagnetics Research Symposium - PIERS 2008. Cambridge (GB), 02.07.2008-06.07.2008] Institutional research plan: CEZ:AV0Z20670512 Keywords : photon * temperature * skin Subject RIV: BO - Biophysics

  12. Translating Greek Drama: Three Czech Electras

    Czech Academy of Sciences Publication Activity Database

    Sarkissian, Alena

    Cambridge : Cambridge Scholars Press, 2007 - (Šípová, P.; Sarkissian, A.), s. 183-195 ISBN 978-1-84718-318-7 Institutional research plan: CEZ:AV0Z90090514 Keywords : drama * translation * theatre Subject RIV: AB - History

  13. Proteomes and Neural Stem Cells: cellular signalling during differentiation

    Czech Academy of Sciences Publication Activity Database

    Skalníková, Helena; Halada, Petr; Vodička, Petr; Motlík, Jan; Horning, O.; Jensen, O. N.; Gadher, S. J.; Pelech, S.; Kovářová, Hana

    Cambridge : -, 2007, s. 1-1. [BSPR-EBI Meeting: Integrative Proteomics: From Molecules to Systems,. Cambridge (GB), 25.07.2007-27.07.2007] Institutional research plan: CEZ:AV0Z50450515; CEZ:AV0Z50200510 Keywords : neural stem cells * differentiation * signalling * proteome Subject RIV: EB - Genetics ; Molecular Biology

  14. Principles of Constraint Programming and Constraint Processing: A Review

    OpenAIRE

    Van Der Beek, Peter; Walsh, Toby

    2004-01-01

    Review of Apt, Krzysztof. "Principles of Constraint Programming. Cambridge, England: Cambridge University Press. ISBN: 0- 521-825830. 420 pages, $50.00. Publication Date: August 2003. Review also of Dechter, Rina. "Constraint Processing. San Francisco: Morgan Kaufmann Publishers. ISBN 1-55860-890-7. 481 pages, $65.95. Publication Date: May 2003.

  15. Räägi, mälupoliitika / Maria Mälksoo

    Index Scriptorium Estoniae

    Mälksoo, Maria, 1979-

    2010-01-01

    Arvustus: Memory and Power in Post-War Europe. Studies in the Presence of the Past. Cambridge University Press, Cambridge, 2002 ; The Politics of Memory in Postwar Europe. Duke University Press, Durham and London, 2006 ; Memory, Trauma and World Politics. Reflections on the Relationship Between Past and Present. Palgrave Macmillan. Houndmills, Basingstoke, Hampshire, 2006

  16. Gödel's Ontological Proof and its Variants

    Czech Academy of Sciences Publication Activity Database

    Hájek, Petr

    Cambridge : Cambridge University Press, 2011 - (Baaz, M.; Papadimitriou, C.; V, H.; Scott, D.; Harper, C.), s. 307-321 ISBN 978-0-521-76144-4 R&D Projects: GA AV ČR IAA100300503 Institutional research plan: CEZ:AV0Z10300504 Keywords : ontological proof * Gödel Subject RIV: BA - General Mathematics

  17. RBS/channelling study of Er+ ion-implanted lithium niobate structure after an annealing procedure

    Czech Academy of Sciences Publication Activity Database

    Macková, Anna; Malinský, Petr; Švecová, B.; Nekvindová, P.; Grotzschel, R.

    Cambridge: IOP, Institute of physics, 2009. [19th International conference on Ion beam analysis . 07.09.2009-11.09.2009, Cambridge] R&D Projects: GA MŠk(CZ) LC06041 Institutional research plan: CEZ:AV0Z10480505 Keywords : Lithium niobate * Erbium * Ion implantation * RBS/channelling Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  18. Argon plasma irradiation of polypropylene

    Czech Academy of Sciences Publication Activity Database

    Vasina, A.; Malinský, Petr; Slepička, P.; Macková, Anna; Švorčík, V.

    Cambridge: IOP, Institute of physics, 2009. s. 83-83. [19th International conference on Ion beam analysis . 07.09.2009-11.09.2009, Cambridge] R&D Projects: GA MŠk(CZ) LC06041 Institutional research plan: CEZ:AV0Z10480505 Keywords : polypropylene * plasma treatment * RBS * XPS * zeta potential Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  19. 76 FR 14379 - Advanced Placement Incentive Program; Office of Elementary and Secondary Education; Overview...

    Science.gov (United States)

    2011-03-16

    ... Cambridge International A and AS Levels administered by Cambridge University International Examinations. As... placement courses and tests. The program expands opportunities for low-income students to take college-level...: Promoting Science, Technology, Engineering, and Mathematics (STEM) Education and the competitive...

  20. Migrating Art History

    DEFF Research Database (Denmark)

    Ørum, Tania

    2012-01-01

    Review of Hiroko Ikegami, The Great Migrator. Robert Rauschenberg and the Global Rise of American Art. Cambridge Mass., The MIT Press, 2010. 277 pages. ISBN 978-0-262-01425-0.......Review of Hiroko Ikegami, The Great Migrator. Robert Rauschenberg and the Global Rise of American Art. Cambridge Mass., The MIT Press, 2010. 277 pages. ISBN 978-0-262-01425-0....

  1. Critique of Fault-Tolerant Quantum Information Processing

    OpenAIRE

    Alicki, Robert

    2013-01-01

    This is a chapter in a book \\emph{Quantum Error Correction} edited by D. A. Lidar and T. A. Brun, and published by Cambridge University Press (2013)\\\\ (http://www.cambridge.org/us/academic/subjects/physics/quantum-physics-quantum-information-and-quantum-computation/quantum-error-correction)\\\\ presenting the author's view on feasibility of fault-tolerant quantum information processing.

  2. An Introduction to Topological Quantum Codes

    OpenAIRE

    Bombin, H.

    2013-01-01

    This is the chapter \\emph{Topological Codes} of the book \\emph{Quantum Error Correction}, edited by Daniel A. Lidar and Todd A. Brun, Cambridge University Press, New York, 2013. http://www.cambridge.org/us/academic/subjects/physics/quantum-physics-quantum-information-and-quantum-computation/quantum-error-correction

  3. The Best That Has Been Thought and Said?

    Science.gov (United States)

    Alexander, Robin

    2014-01-01

    "FORUM" has marked the progress of the Cambridge Primary Review by three previous articles from Robin Alexander, the Review's director, and by critiques and responses from several others, notably "FORUM"'s Michael Armstrong. In 2013 the Review was superseded by the Cambridge Primary Review Trust, and this article is…

  4. Improved chronology of magmatic and hydrothermal events in the Příbram ore region, Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Žák, Karel; Svojtka, Martin; Ackerman, Lukáš; Breiter, Karel; Haluzová, Eva; Ďurišová, Jana; Pašava, J.; Veselovský, F.

    Cambridge : Cambridge, 2015. s. 3562-3562. [Goldschmidt Conference /25./. 16.08.2015-21.08.2015, Prague] Institutional support: RVO:67985831 Keywords : Příbram ore region * magmatic events * Hydrothermal events Subject RIV: DB - Geology ; Mineralogy http://goldschmidt.info/2015/uploads/abstracts/finalPDFs/3562.pdf

  5. On the approximation of a nonlinear aeroelastic problem by finite elment method

    Czech Academy of Sciences Publication Activity Database

    Sváček, P.; Horáček, Jaromír

    Cambridge, USA : Massachusetts Institute of Technology, 2007. s. 39-39. [Fourth M.I.T. Conference on Computational Fluid and Solid Mechanics. 13.06.2007-15.06.2007, Cambridge] R&D Projects: GA AV ČR IAA200760613 Institutional research plan: CEZ:AV0Z20760514 Keywords : numerical simulations * aeroelastic instability * ALE method Subject RIV: BI - Acoustics

  6. The interaction of an Hii region with a fractal molecular cloud

    Czech Academy of Sciences Publication Activity Database

    Walch, S.; Whitworth, A.; Bisbas, Thomas G.; Wünsch, Richard; Hubber, D.A.

    Cambridge : Cambridge University Press, 2011 - (Alves, J.), s. 323-326 ISBN 9780521766432. ISSN 1743-9213. - (IAU Symposium Proceedings Series. S270). [Symposium of the International Astronomical Union /270./. Barcelona (ES), 31.05.2010-04.06.2010] Institutional research plan: CEZ:AV0Z10030501 Keywords : hydrodynamics * numerical methods * stars formation Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  7. Seedlings Finally Get Their Due: Book Review of Seedling Ecology and Evolution

    Science.gov (United States)

    Book Review of: Seedling Ecology and Evolution. Ed. Leck, Mary Allessio, Parker, V. Thomas and Simpson, Robert L. Cambridge University Press, Cambridge, UK. 2008. Many plant demographers find themselves, at some point, staring at a dataset full of detailed information on juvenile and adult plants,...

  8. Social protection in the enterprises: the case of Slovakia

    Czech Academy of Sciences Publication Activity Database

    Plánovský, Ján; Wörgötter, A.

    Cambridge [u.a.] : Cambridge University Press, 1997 - (Rein, M.; Friedman , B.; Wörgötter, A.), s. 227-260 ISBN 0521584035. [Enterprise and social benefits after communism. Wien (AT), 25.03.1994-26.03.1994] Keywords : social protection * enterprises * Slovakia Subject RIV: AH - Economics

  9. Wage and non-wage labour costs in the Czech Republic - the impact of fringe benefits

    Czech Academy of Sciences Publication Activity Database

    Filer, R. K.; Schneider, O.; Švejnar, Jan

    Cambridge : Cambridge University Press, 1997 - (Rein, M.; Friedman , B.; Wörgötter, A.), s. 75-94 ISBN 0-521-58403-5 Institutional research plan: CEZ:AV0Z7085904 Keywords : Wage and non-wage labour costs * Czech Republic * fringe benefits Subject RIV: AH - Economics

  10. The analysis of stratosphere using MERRA reanalysis and CCM SOCOL v3.0

    Czech Academy of Sciences Publication Activity Database

    Kozubek, Michal; Križan, Peter; Rozanov, E.

    Cambridge : British Antarctic Survey, 2014. s. 31-31. [Workshop on Long-Term Changes and Trends in the Atmosphere 2014 /8./. 28.07.2014 - 31.07.2014, Cambridge] Institutional support: RVO:68378289 Subject RIV: DG - Athmosphere Sciences, Meteorology ftp://ftp.bas.ac.uk/andkav/Trends_Presentations/Trends_Delegates_Abstract_Book.pdf

  11. Development and validity of the Emotion and Motivation Self-Regulation Questionnaire (EMSR-Q)

    OpenAIRE

    Alonso Tapia, Jesús; Panadero Calderón, Pedro Ernesto; Díaz Ruiz, Miguel Ángel

    2014-01-01

    Subject to file availability and provided the posting includes a prominent statement of the full bibliographical details, a copyright notice in the name of the copyright holder (Cambridge University Press or the sponsoring Society, as appropriate), and a link to the online edition of the journal at Cambridge Journals Online.

  12. Gravitating Disks Around Black Holes

    Czech Academy of Sciences Publication Activity Database

    Karas, Vladimír; Šubr, Ladislav

    Cambridge : Cambridge University Press, 2010 - (Peterson, B.), s. 332-332 ISBN 978-0-521-76502-2. - (IAU Symposium Proceedings Series. 267). [Symposium of the International Astronomical Union /267./. Rio de Janeiro (BR), 10.08.2009-14.08.2009] Institutional research plan: CEZ:AV0Z10030501 Keywords : accretion disks * gravitation * black hole physics Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  13. Commission 7: Celestial Mechanics and Dynamical Astronomy. Triennial Report 2006-2009

    Czech Academy of Sciences Publication Activity Database

    Burns, J.A.; Kneževic, Z.; Milani, A.; Vokrouhlický, D.; Athanassoula, E.; Beaugé, C.; Erdi, B.; Lemaitre, A.; Maciejewski, A.; Malhotra, R.; Morbidelli, A.; Peale, S.J.; Šidlichovský, Miloš; Zhou, J.-L.

    Cambridge: Cambridge University Press, 2009 - (van der Hucht, K.), s. 12-22. (Proceedings of the IAU. IAU Transactions. 27A). ISBN 978-0-521-85605-8 Institutional research plan: CEZ:AV0Z10030501 Keywords : celestial mechanics * resonances * exoplanets Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  14. COMMISSION 7: Celestial Mechanics and Dynamical Astronomy

    Czech Academy of Sciences Publication Activity Database

    Milani, A.; Burns, J.A.; Hadjidemetriou, J.; Kneževic, Z.; Beaugé, C.; Erdi, B.; Fukushima, T.; Heggie, D. C.; Lemaitre, A.; Maciejewski, A.; Morbidelli, A.; Šidlichovský, Miloš; Vokrouhlický, D.; Zhou, J.-L.

    Cambridge: Cambridge University Press, 2007 - (Engvold, O.), s. 7-16. (Proceedings of the IAU. IAU Transactions. 26A). ISBN 978-0-521-85604-1 Institutional research plan: CEZ:AV0Z10030501 Keywords : celestial mechanics * resonances * exoplanets Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  15. Modeling of the Be Stars

    Czech Academy of Sciences Publication Activity Database

    Šejnová, Klára; Votruba, Viktor; Koubský, Pavel

    Cambridge: Cambridge University Press, 2012 - (Richards, M.), s. 261-262. (Proceedings of the International Astronomical Union. IAU S282). ISBN 9781107019829. ISSN 1743-9213. [Symposium of the International Astronomical Union /282./. Tatranská Lomnica (SK), 18.07.2011-22.07. 2011] Institutional support: RVO:67985815 Keywords : Be stars * shellspec * genetic algorithms Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  16. Summary of Observational Techniques

    Czech Academy of Sciences Publication Activity Database

    Koubský, Pavel

    Cambridge: Cambridge University Press, 2012 - (Richards, M.), s. 557-561. (Proceedings of the International Astronomical Union. IAU S282). ISBN 9781107019829. ISSN 1743-9213. [Symposium of the International Astronomical Union /282./. Tatranská Lomnica (SK), 18.07.2011-22.07. 2011] Institutional support: RVO:67985815 Keywords : observational techniques * binary stars Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  17. Commission 7: Celestial Mechanics and Dynamical Astronomy

    Czech Academy of Sciences Publication Activity Database

    Burns, J.A.; Kneževic, Z.; Milani, A.; Athanassoula, E.; Beaugé, C.; Bálint, E.; Lematre, A.; Maciejewski, A.; Malhotra, R.; Morbidelli, A.; Peale, S.J.; Šidlichovský, Miloš; Vokrouhlický, D.; Zhou, J.

    Cambridge: Cambridge University Press, 2010 - (Corbett, I.), s. 120-122. (Proceedings of the International Astronomical Union. IAU Transactions. 27B). ISBN 978-0-521-76831-3 Institutional research plan: CEZ:AV0Z10030501 Keywords : celestial mechanics * resonances * exoplanets Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

  18. İstanbul Üniversitesi Fen Fakültesi’nde Parçacık Hızlandırıcıları

    OpenAIRE

    Ata, Kaan

    2014-01-01

    Bilim Kitapları 161, İkinci Basım, Ankara 2002, s.122. Jeff Hughes, “Radioactivity and Nuclear Physics,” The Cambridge History of Science Volume 5: The Modern Physical and Mathematical Sciences, Ed. Mary Jo Nye, Cambridge University Press, 2003, s.365-366

  19. Environmental Social Sciences: Methods and Research Design

    OpenAIRE

    Jeremy Spoon

    2012-01-01

    Review of Environmental Social Sciences: Methods and Research Design. Ismael Vaccaro, Eric Alden Smith, and Shankar Aswani, eds. 2010. Cambridge University Press, Cambridge. Pp. 396, 41 b/w illustrations, 20 tables. US$49.99 (paperback). ISBN 9780521125710.

  20. Capital in the Twenty-First Century

    DEFF Research Database (Denmark)

    Hansen, Per H.

    2014-01-01

    Review essay on: Capital in the Twenty-First Century. By Thomas Piketty . Translated by Arthur Goldhammer . Cambridge, Mass.: The Belknap Press of Harvard University Press, 2014. viii + 685 pp......Review essay on: Capital in the Twenty-First Century. By Thomas Piketty . Translated by Arthur Goldhammer . Cambridge, Mass.: The Belknap Press of Harvard University Press, 2014. viii + 685 pp...