WorldWideScience

Sample records for bp010009 cambridge biotech

  1. Cambridge Analytica

    OpenAIRE

    ANTOR Md Ahsan Habib

    2018-01-01

    10 mintures presentation slides for Cambridge Analytica...... You will get a glimpse idea about the biggest data scandal of 2018. If your are preparing for IT security presentation , I believe this would help you to understand about the basic idea & reason of the CA.

  2. Profiles of four projects in Biotech Business

    DEFF Research Database (Denmark)

    Valentin, Finn

    2004-01-01

    In April 2004, Copenhagen Business School opens a centre for research on biotech business. Biotech Business includes a number of senior and junior researchers from CBS. Initially the centre takes its point of departure in four projects included in the research program on Competence, Organisation...... and Management in Biotech Industries (COMBI). Starting in March 2004, COMBI is funded jointly by The Danish Social Research Council, firms and organisations in the Danish biotech industry and CBS. This presentation refers exclusively to four COMBI projects....

  3. A global need for women's biotech leadership

    DEFF Research Database (Denmark)

    Smith-Doerr, L.; Kemekliene, G.; Teutonico, R.

    2011-01-01

    Increasing women's participation in leadership of biotech policy making, funding, research and implementation will strengthen the race to solve global problems......Increasing women's participation in leadership of biotech policy making, funding, research and implementation will strengthen the race to solve global problems...

  4. Does medical mystery threaten biotech

    Energy Technology Data Exchange (ETDEWEB)

    Raphals, P.

    1990-11-02

    A puzzling medical syndrome caused by substances grown in a genetically engineered bacterium could have profound consequences for the entire biotechnology industry-if Jeremy Rifkin has his way. Rifkin, the controversial biotech critic, has filed a petition based on the eosinophilia-myalgia syndrome (EMS) with the Food and Drug Administration. In it, he asks that the FDA's review of all products made by genetic engineering techniques be suspended until strict new rules are in place to protect the public. The problem is that no one yet knows whether the specific contaminant that has caused up to 5000 EMS cases and 27 deaths was actually the result of genetic engineering. It might well have been the result of problems with chemical purification steps that have little to do with molecular genetics. Until now there has been no way to resolve that uncertainty. But help is on the way-in the form of a recently published animal model of the disease that should eventually enable researchers to pinpoint the precise cause of the syndrome.

  5. Business Ethics 101 for the biotech industry.

    Science.gov (United States)

    MacDonald, Chris

    2004-01-01

    Biotechnology companies face ethical challenges of two distinct types: bioethical challenges faced on account of the nature of work in the life sciences, and corporate ethical challenges on account of their nature as commercial entities. The latter set of challenges has received almost no attention at all in the academic literature or media. This paper begins to remedy that lacuna, examining ethical issues that arise specifically on account of the status of biotech companies as commercial entities. The focus here is on three representative issues: product safety, corporate social responsibility, and corporate governance. It is argued that each of these issues poses particular ethical challenges for companies in the biotech sector. In the area of product safety, it is noted that biotech companies face particular challenges in determining what counts as a "safe" product, given the contentious nature of what might count as a "harm" in the biotech field. In the area of corporate social responsibility, the adoption of a "stakeholder approach" and an attempt to manage the social consequences of products pose special challenges for biotech companies. This is due to the enormous range of groups and individuals claiming to have a stake in the doings of such companies, and the trenchant controversies over just what the social consequences of various biotechnologies might be. In the area of corporate governance, biotech companies need to seek out and follow best practices regarding the ways in which information, authority, and influence flow between a company's shareholders, managers, and Board of Directors, if they are to avoid duplicating the ethical and financial scandal that brought down ImClone. An important meta-issue, here--one that renders each of these corporate ethical challenges more vexing--is the difficulty of finding the appropriate benchmarks for ethical corporate behavior in a field as controversial, and as rapidly evolving, as biotechnology. Three

  6. Entrepreneurial culture in innovative biotech clusters.

    NARCIS (Netherlands)

    Ruel, Hubertus Johannes Maria; Frolova, P.; Groen, Arend J.

    2012-01-01

    This paper presents a study on the determinants of entrepreneurial culture in innovative biotech clusters. A literature review led to the identification of nine determinants. For the empirical study four clusters in Western Europe with a high entrepreneurial culture were selected. Cluster

  7. Investor Outlook: After the Biotech Bubble Popped.

    Science.gov (United States)

    Schimmer, Joshua; Breazzano, Steven; Yang, Jerry

    2016-03-01

    After a few torrid years of value appreciation, the biotech "bubble" has precipitously popped over the past few months. In this report, we take a look at some of the factors that drove the run-up in valuations, the triggers that led to their substantial pullback, and where the industry may be headed from here. Gene therapy/editing companies have been particularly affected by these dynamics, raising a new set of questions and challenges for the group.

  8. Biotech Business Lessons for Defense Acquisition

    Science.gov (United States)

    2016-01-01

    repudiates what func- tional personnel hold dear—that their hurdles are vital to some moral or ethical responsibility to protect or safeguard...94 Strategic Studies Quarterly ♦ Summer 2016 Biotech Business Lessons for Defense Acquisition Col David L. Peeler Jr., USAF Abstract The desire to...examples and lessons from private business sectors would serve DOD interests well. ✵ ✵ ✵ ✵ ✵ Acquisition reform! No other two words so stress or trouble

  9. 77 FR 35353 - Biotech Life Sciences Trade Mission to Australia

    Science.gov (United States)

    2012-06-13

    ... DEPARTMENT OF COMMERCE International Trade Administration Biotech Life Sciences Trade Mission to... Commercial Service (CS) is organizing a Biotech Life Sciences trade mission to Australia, October 29-November.... biotechnology and life science firms. The goals of the trade mission to Australia are to (1) increase U.S...

  10. International Commercial Contracts, by Giuditta Cordero Moss. (Cambridge: Cambridge University Press, 2014)

    DEFF Research Database (Denmark)

    Lando, Ole

    2015-01-01

    Review of: Giuditta Cordero Moss, International Commercial Contracts. Cambridge: Cambridge University Press, 2014. XV + 329 pages. ISBN: 9781107684713......Review of: Giuditta Cordero Moss, International Commercial Contracts. Cambridge: Cambridge University Press, 2014. XV + 329 pages. ISBN: 9781107684713...

  11. Indian Biotech Bazaar: a swot analysis.

    Science.gov (United States)

    Kumar, Abhishek

    2007-05-01

    Biotechnology is a life science-based technique especially used in agriculture, medicine and food sciences. It is generally defined as the manipulation in organisms to generate products for the welfare of the world. Biotechnology combines disciplines such as genetics, biochemistry, microbiology, and cell biology along with information technology, chemical engineering, robotics etc. It includes basic industries such as food processing, tissue culture, plant development and other sophisticated ones such as recombinant therapeutics and diagnostics. Biotechnology, globally recognized as a rapidly emerging and far-reaching technology, is aptly described as the "technology of hope" for its promise of food, health and environmental sustainability. In India, biotechnology employs more than 10 000 people and generates roughly US$ 500 million in revenue annually. The biotechnology market has increased its sales from Rs. 50 billion in 1997 to Rs.70 billion in 2000, and is expected to cross Rs. 240 billion by the year 2010. In India, the human health biotech products account for 60% of the total market; agribiotech and veterinary 25%, medical devices, contract research and development (R&D), reagents and supplies constitute the remaining 15% Moreover, to facilitate foreign investment, capital and government policies are being revised. Other important industries include industrial enzyme manufacture, bioinformatics, and medical devices. Biotechnology has had limited appeal so far on our capital markets, and we have less then a dozen biotech companies listed on the public markets.

  12. Reflections on Cambridge: John Maynard Keynes at King's College Cambridge

    OpenAIRE

    Macfarlane, Alan

    2012-01-01

    .mp4 video file The economist John Maynard Keynes spent much of his life in Cambridge, connected to King's College. Alan Macfarlane reflects on a few aspects of his life and work. Filmed by Xu Bei in 2010

  13. Financial risk of the biotech industry versus the pharmaceutical industry.

    Science.gov (United States)

    Golec, Joseph; Vernon, John A

    2009-01-01

    The biotech industry now accounts for a substantial and growing proportion of total R&D spending on new medicines. However, compared with the pharmaceutical industry, the biotech industry is financially fragile. This article illustrates the financial fragility of the biotech and pharmaceutical industries in the US and the implications of this fragility for the effects that government regulation could have on biotech firms. Graphical analysis and statistical tests were used to show how the biotech industry differs from the pharmaceutical industry. The two industries' characteristics were measured and compared, along with various measures of firms' financial risk and sensitivity to government regulation. Data from firms' financial statements provided accounting-based measures and firms' stock returns applied to a multifactor asset pricing model provided financial market measures. The biotech industry was by far the most research-intensive industry in the US, averaging 38% R&D intensity (ratio of R&D spending to total firm assets) over the past 25 years, compared with an average of 25% for the pharmaceutical industry and 3% for all other industries. Biotech firms exhibited lower and more volatile profits and higher market-related and size-related risk, and they suffered more negative stock returns in response to threatened government price regulation. Biotech firms' financial risks increase their costs of capital and make them more sensitive to government regulations that affect their financial prospects. As biotech products grow to represent a larger share of new medicines, general stock market conditions and government regulations could have a greater impact on the level of innovation of new medicines.

  14. Clark and Prehistory at Cambridge

    Directory of Open Access Journals (Sweden)

    Pamela Jane Smith

    1996-05-01

    Full Text Available If honours and titles give measure of a man, then Professor Sir Grahame Clark was indeed important. Faculty Assistant Lecturer in the Faculty of Archaeology and Anthropology at Cambridge University from 1935-46, University Lecturer 1946-52, Disney Professor of Archaeology 1952-74, Head of the Department of Archaeol­ogy and Anthropology 1956-61 and 1968-71, Fellow of Peterhouse, Cambridge 1950-73, Master of Peterhouse 1973-80, he was a visiting lecturer at diverse universities; appointed CBE in 1971, he received many awards includ­ing the prestigious Erasmus Prize for 1990, presented by Prince Bernhard of the Netherlands, for his "long and inspiring devotion to prehistory" (Scarre 1991:10; and in June 1992, he was knighted. Yet well before fame and position were rewards, Clark made major contributions to the establishment of prehis­tory as an academic subject at Cambridge University. Cambridge was the first and, for many years, only British university granting an undergraduate degree which offered prehistory as a specialization. "The development of postgraduate research in prehistoric archaeology at Cambridge had to wait on the provision of undergraduate teaching;' Clark (1989b: 6 recently observed. The "faculty was the only one in Britain producing a flow of graduates in prehistoric archaeology" (Clark 1989a: 53.

  15. Cambridge IGCSE English first language

    CERN Document Server

    Reynolds, John

    2013-01-01

    Revised edition for the 2015 syllabus to help your students prepare for their examination and enhance their enjoyment of English. This title has been written for the revised Cambridge IGCSE First Language English (0500 and 0522) syllabuses, for first teaching from 2013. ? Develops the skills necessary to become a better reader and writer. ? Offers detailed advice and preparation for the examination. ? Teaches skills for successful writing of essays and coursework assignment. We are working with Cambridge International Examinations to gain endorsement for this title.

  16. The Cambridge encyclopaedia of astronomy

    CERN Document Server

    1977-01-01

    Astronomy has been transformed in the last two decades by a series of dramatic discoveries that have left most reference books completely out of date. The Cambridge Encyclopaedia of Astronomy presents a broadly based survey of the whole of astronomy which places emphasis on these critical new findings.

  17. The Cambridge crystallography subroutine library

    International Nuclear Information System (INIS)

    Brown, P.J.; Matthewman, J.C.

    1981-06-01

    This manual is an amalgamation of the original Cambridge Crystallography Subroutine Library Mark II manual and its supplement No I. The original Mark II system, a set of FORTRAN Subroutines which can be used for standard crystallographic calculations, has been extended to include facilities for conventional least squares refinement. Several new routines have also been added. (U.K.)

  18. 76 FR 17621 - Biotech Life Science Trade Mission to China

    Science.gov (United States)

    2011-03-30

    ... DEPARTMENT OF COMMERCE International Trade Administration Biotech Life Science Trade Mission to... Commercial Service (CS) is organizing a Biotechnology Life Sciences trade mission to China on October 17-20... representatives from a variety of U.S. biotechnology and life science firms and trade organizations. The mission...

  19. China's Biotech Policies and Their Impacts on U.S. Agricultural Exports to China

    OpenAIRE

    Song, Baohui; Marchant, Mary A.

    2006-01-01

    China is a key player in global agricultural markets, and the number one importer of U.S. soybeans and cotton, whereby soybeans and cotton are two of the main biotech commodities commercialized in the United States. As of 2005, 87% of soybeans and 79% of cotton planted in the U.S. were biotech. Thus, changes in China's biotech policies may have a significant impact on U.S. biotech commodity exports to China. An understanding of the evolution of China's biotech regulations and factors that may...

  20. The Cambridge Behavioural Inventory revised.

    Science.gov (United States)

    Wear, Helen J; Wedderburn, Catherine J; Mioshi, Eneida; Williams-Gray, Caroline H; Mason, Sarah L; Barker, Roger A; Hodges, John R

    2008-01-01

    Neurobehavioural and psychiatric symptoms are common in a range of neurodegenerative disorders with distinct profiles which are helpful in the diagnosis and monitoring of these disorders. The Cambridge Behavioural Inventory (CBI) has been shown to distinguish frontotemporal dementia (FTD), Alzheimer's disease (AD), Huntington's disease (HD) and Parkinson's disease (PD), but it is lengthy. To develop a shorter version of the 81 item CBI. CBI data from 450 participants with behavioural variant frontotemporal dementia (bv-FTD) (64), AD (96), PD (215) and HD (75) were analysed using Principal Components Analysis and measures of internal consistency (Cronbach alpha). A reduced 45-item questionnaire was developed. The instrument identified distinct behavioural profiles and performed as well as the original version. A shorter (45 item) version of the CBI is capable of differentiating bv-FTD and AD from PD and HD. It may be useful in delineating the type and extent of problems in these disorders as well as monitoring therapeutic interventions.

  1. How quantum physics came to Cambridge

    International Nuclear Information System (INIS)

    McCrea, William

    1985-01-01

    The paper traces the early stages of quantum physics, in Cambridge, in the 1920's. The mathematicians who inspired a generation of quantum physicists are briefly described, as well as the work of Dirac on quantum mechanics. The author's own contribution to quantum mechanics is outlined, along with other work in physics carried out at that time in Cambridge. (U.K.)

  2. Trial access to Cambridge University Press ebooks

    CERN Multimedia

    CERN Library

    2011-01-01

    From 1 August till 31 October, CERN users are invited to enjoy a trial access to all Cambridge University Press electronic books: http://ebooks.cambridge.org/. Please don't hesitate to send feedback to library.desk@cern.ch.

  3. Cambridge community Optometry Glaucoma Scheme.

    Science.gov (United States)

    Keenan, Jonathan; Shahid, Humma; Bourne, Rupert R; White, Andrew J; Martin, Keith R

    2015-04-01

    With a higher life expectancy, there is an increased demand for hospital glaucoma services in the United Kingdom. The Cambridge community Optometry Glaucoma Scheme (COGS) was initiated in 2010, where new referrals for suspected glaucoma are evaluated by community optometrists with a special interest in glaucoma, with virtual electronic review and validation by a consultant ophthalmologist with special interest in glaucoma. 1733 patients were evaluated by this scheme between 2010 and 2013. Clinical assessment is performed by the optometrist at a remote site. Goldmann applanation tonometry, pachymetry, monoscopic colour optic disc photographs and automated Humphrey visual field testing are performed. A clinical decision is made as to whether a patient has glaucoma or is a suspect, and referred on or discharged as a false positive referral. The clinical findings, optic disc photographs and visual field test results are transmitted electronically for virtual review by a consultant ophthalmologist. The number of false positive referrals from initial referral into the scheme. Of the patients, 46.6% were discharged at assessment and a further 5.7% were discharged following virtual review. Of the patients initially discharged, 2.8% were recalled following virtual review. Following assessment at the hospital, a further 10.5% were discharged after a single visit. The COGS community-based glaucoma screening programme is a safe and effective way of evaluating glaucoma referrals in the community and reducing false-positive referrals for glaucoma into the hospital system. © 2014 Royal Australian and New Zealand College of Ophthalmologists.

  4. Cambridge Bay: Six years later

    International Nuclear Information System (INIS)

    Edworthy, J.

    1992-01-01

    The story of a wind energy project in Cambridge Bay, Northwest Territories, is presented from the perspective of the company that supplied the equipment and supported the project through its life. The project was intended to demonstrate the technical, economic, institutional, and operational issues and barriers to the use of wind power in remote communities. The system, involving four Carter Model 25 units each rated at 25 kW, was installed in 1987 and commissioned in January 1988. Shortly thereafter, the Northern Canada Power Commission (which requested the project in the first place) was taken over by the territorial administration, and employee continuity was disrupted. At about the same time, Federal support for the project decreased. Technical problems included a transformer failure, a generator failure, and a failed yaw tube which turned out to be lightly designed and poorly made. The Carter turbine company also went out of business, making spare parts difficult to obtain. The utility organization changed abruptly in summer 1991 with the arrival of a new area superintendent who did not support the project. The wind farm was shut down in 1992. The project generated a total of 160,982 kWh with over 71% availability. The positive and negative results from the project are summarized and recommendations are made for future Arctic wind power projects. 2 figs., 1 tab

  5. Implementation of the resource recovery concept in the biotech industry

    DEFF Research Database (Denmark)

    Mitic, Aleksandar; Mansouri, Seyed Soheil; S.B.A. Udugama, Isuru

    The concept of circular economy is attracting significant attention in modern biotech industry. Downstream processing plants are usually focused on the removal of impurities instead of their recovery in the form of value-added products for additional revenues. For example, carboxylic acids......, carbohydrates, proteins, lipids, inorganic ions and water itself are amongst various resources that are found in wastewater streams coming from bio-based production processes. Such compounds have a high value at the global market and could potentially be used as raw materials for the manufacturing feed and food...

  6. Deutsche Biotech-Unternehmen und ihre Innovationsfähigkeit im internationalen Vergleich : eine institutionentheoretische Analyse

    NARCIS (Netherlands)

    Lange, K.S.G.

    2006-01-01

    German Biotech-Companies and their Innovativeness in International Comparison – an Institutionalist Analysis 1 Introduction In the mid-1990s, legal changes and policy initiatives in Germany led to the rapid emergence of a biotechnology industry. Initially, German biotech companies focused on the

  7. The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008

    NARCIS (Netherlands)

    Heimeriks, Gaston; Boschma, Ron

    2014-01-01

    This study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986-2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new

  8. The path- and place-dependent nature of scientific knowledge production in biotech 1986-2008

    NARCIS (Netherlands)

    Heimeriks, G.J.; Boschma, R.

    2013-01-01

    This study explores the worldwide spatial evolution of scientific knowledge production in biotechnology in the period 1986–2008. We employ new methodology that identifies new key topics in biotech on the basis of frequent use of title worlds in major biotech journals as an indication of new

  9. A global overview of biotech (GM) crops: adoption, impact and future prospects.

    Science.gov (United States)

    James, Clive

    2010-01-01

    In the early 1990s, some were skeptical that genetically modified (GM) crops, now referred to as biotech crops, could deliver improved products and make an impact at the farm level. There was even more skepticism that developing countries would adopt biotech crops. The adoption of and commercialization of biotech crops in 2008 is reviewed. The impact of biotech crops are summarized including their contribution to: global food, feed and fiber security; a safer environment; a more sustainable agriculture; and the alleviation of poverty, and hunger in the developing countries of the world. Future prospects are discussed. Notably, Egypt planted Bt maize for the first time in 2008 thereby becoming the first country in the Arab world to commercialize biotech crops.

  10. State Incentives for Innovation, Star Scientists, and Jobs: Evidence from Biotech. Upjohn Institute Working Paper No. 14-203

    Science.gov (United States)

    Moretti, Enrico; Wilson, Daniel J.

    2013-01-01

    We evaluate the effects of state-provided financial incentives for biotech companies, which are part of a growing trend of placed-based policies designed to spur innovation clusters. We estimate that the adoption of subsidies for biotech employers by a state raises the number of star biotech scientists in that state by about 15 percent over a…

  11. Cambridge IGCSE mathematics core and extended

    CERN Document Server

    Pimentel, Ric

    2013-01-01

    The most cost effective and straightforward way to teach the revised syllabus, with all the core and extended content covered by a single book and accompanying free digital resources.  . This title has been written for the revised Cambridge IGCSE Mathematics (0580) syllabus, for first teaching from 2013.  . ·         Gives students the practice they require to deepen their understanding through plenty of questions. ·         Consolidates learning with unique digital resources on the CD, included free with every Student's Book.  . We are working with Cambridge International Examinations to gain

  12. Biotech pilgrims and the transnational quest for stem cell cures.

    Science.gov (United States)

    Song, Priscilla

    2010-10-01

    Thousands of patients with incurable neurodegenerative conditions from more than 60 countries have sought fetal cell transplants in China since 2001. Drawing on 24 months of ethnographic fieldwork, I investigate these transnational encounters occurring in the realm of experimental medicine. Critiquing popular notions of "medical tourism," I develop the alternative concept of "biotech pilgrimage" to reveal how faith intertwines with technology, travel, and the political economies of health care and medical research in a global era. Insights from pilgrimage theory enable us to question assumptions of leisure embedded in claims of tourism while also exploring new biopolitical practices that extend beyond the borders of the nation-state. I also demonstrate how materialist visions of salvation underlie medical practice and contribute to China's rising influence as a global technological leader.

  13. Shaking Up Biotech/Pharma: Can Cues Be Taken from the Tech Industry?

    Science.gov (United States)

    Wang, C Katherine

    2017-06-01

    The biotech and pharma (biotech/pharma) industry is in dire need of finding ways to increase efficacy, efficiency, and affordability of its products. The information and technology industry ("tech") industry, which is an industry similarly founded on inventions and innovation, may provide some food for thought. This perspective will demonstrate the shift that biotech/pharma is already making and will propose that the industry has an opportunity to compel change by adopting some aspects of the tech industry with regards to models for technology/product development and leadership attributes.

  14. The development of China's medical biotech industry needs to be driven by innovation.

    Science.gov (United States)

    Yu, Zailin; Dai, Yuehan

    2006-11-01

    The Chinese biotech industry is going through a period of fast growth, and with its huge population, China is predicted to be the biggest single-country market in the world. However, the Chinese biotech industry has to tackle the critical issue of innovation, which should be the driving force for China's development into an advanced and responsible country. Here, in this article, the authors review the history of the Chinese biotech industry, exemplified by the development of genetically engineered drugs during the last 20 years, and also point out its the future.

  15. Weizmann ties with Cambridge in physics contest

    CERN Multimedia

    Siegel, J

    2004-01-01

    "Scientists and students from the Weizmann Institute of Science in Rehovot and Cambridge University in England have tied for first place in a physics competition aimed at simulating the future functioning of the particle accelerator being built at the European center CERN and due to open in 2007" (1/2 page)

  16. 77 FR 14852 - Advanced Growing Systems, Inc., Advantage Capital Development Corp., Amazon Biotech, Inc...

    Science.gov (United States)

    2012-03-13

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Advanced Growing Systems, Inc., Advantage Capital Development Corp., Amazon Biotech, Inc., Andover Holdings, Inc. a/k/a Andover Energy Holdings, Inc... securities of Amazon [[Page 14853

  17. Mathematics, Science and the Cambridge Tradition

    OpenAIRE

    Nuno Ornelas Martins

    2012-01-01

    Copyright © 2012 World Economics Association. In this paper the use of mathematics in economics will be discussed, by comparing two approaches to mathematics, a Cartesian approach, and a Newtonian approach. I will argue that while mainstream economics is underpinned by a Cartesian approach which led to a divorce between mathematics and reality, the contributions of key authors of the Cambridge tradition, like Marshall, Keynes and Sraffa, are characterised by a Newtonian approach to mathema...

  18. The Swiss biotech referendum: A case study of science communication

    International Nuclear Information System (INIS)

    Cueni, Thomas B.

    1999-01-01

    On June 7 , 1998, the Swiss citizens voted on a constitutional amendment, which could have jeopardised the future of biotechnological research in Switzerland. Scientists and opinion leaders around the world expected the referendum with great anxiety. 'Nature', in an editorial, had firmly stated that the Swiss way showed 'how not to run a country', the 'Economist', a week prior to the referendum, had written that the Swiss might be the only people in the world who decided on their own to forego a world class position in scientific research. In fact, the Swiss did none of that. They rejected the constitutional amendment with an overwhelming majority of 67 per cent of the votes, and what started out as a dramatic threat to scientific research in Switzerland became a platform in favour of modern biotechnology. The presentation addresses some of the key features of the Swiss biotech campaign, analyses the success factors of the campaign, provides an insight in the most in-depth collection of data on public perception of biotechnology in the world, and draws conclusions as to what extent the Swiss experience can be of use in the way to communicate on modem science. The result of the Swiss referendum has convincingly shown that successful communication of modem science is possible if - scientists, authorities, and the industry accept the challenge to cope with the demands of communicating with the public at large, - there is a clear understanding that the public's needs may often be based on psychological rather than on logic scientific reasons, - all participants in the dialogue are willing to forego scientific jargon for clear understandable language, i.e. understand that it is hardly the public's fault if messages do not get across, - everybody accepts that dialogue, information, and education on modem science is a long-haul task. The Swiss biotech referendum was seen as a major threat to Switzerland as a leading country of scientific research. However, something which

  19. 3D-BioPrinting: The future of Red Biotech

    International Nuclear Information System (INIS)

    Crupi, Annunziata; Teodori, Laura

    2015-01-01

    Every day Science moves little steps forward, contributing to the progress of our society. Sometimes, however, a single invention revolutionizes the world. Indeed, the invention of woodblock printing and development of industrial-scale printing-press in the 15. century have changed our society. 3D-printing is now boosting another revolution. The production of custom-made objects from a virtual model will trigger a rapid development of a more versatile, less expensive manufacturing sector for the on-demand market. The real revolution, however, is represented by 3D-printing in biomedicine. 3D-bioprinting represents the future of the Red-Biotech. This technology, indeed, will be able to build ex-novo organs using biocompatible materials and human cells; replace the allograft transplants, eliminating waiting lists that often make the difference between life and death; and provide more predictive, less expensive experimental models, replacing animal tests. The high innovation content of this technology, can make the difference between being obsolete and new [it

  20. 76 FR 13665 - Cambridge Tool & Die, Including On-Site Leased Workers From Action Total Staffing, Cambridge, OH...

    Science.gov (United States)

    2011-03-14

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-74,605] Cambridge Tool & Die... Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of the Trade Act of 1974... of Cambridge Tool & Die, Cambridge, Ohio. The workers are engaged in the production of plastic...

  1. Cambridge IGCSE english as a second language

    CERN Document Server

    Reynolds, John

    2014-01-01

    Revised edition for the 2015 syllabus offering the easiest and most cost effective way to teach both the speaking and listening components with one set of books covering two years and free digital material. This title has been written for the revised Cambridge IGCSE English as a Second Language (0510 and 0511) syllabuses, for first teaching from 2013. ? Prepares students for their exams with a focus on assessed language features, such as inference, opinion and attitude. ? Develops language abilities at an appropriate pace with extra interactive tests on a free CD-ROM. We are working with Cambr

  2. The new Cambridge English course student 1

    CERN Document Server

    Swan, Michael

    1991-01-01

    The New Cambridge English Course is a course teachers and students can rely on to cover the complete range and depth of language and skills needed from beginner to upper-intermediate level. Each level is designed to provide at least 72 hours of class work using the Student's Book, with additional self-study material provided in the Practice Book. The course has a proven multi-syllabus approach which integrates work on all the vital aspects of language study: grammar, vocabulary, pronunciation, skills, notions and functions.

  3. Trends in global approvals of biotech crops (1992–2014)

    Science.gov (United States)

    Aldemita, Rhodora R; Reaño, Ian Mari E; Solis, Renando O; Hautea, Randy A

    2015-01-01

    ABSTRACT With the increasing number of genetically modified (GM) events, traits, and crops that are developed to benefit the global population, approval of these technologies for food, feed, cultivation and import in each country may vary depending on needs, demand and trade interest. ISAAA established a GMO Approval Database to document global approvals of biotech crops. GM event name, crops, traits, developer, year of approval for cultivation, food/feed, import, and relevant dossiers were sourced from credible government regulatory websites and biosafety clearinghouses. This paper investigates the trends in GM approvals for food, feed and cultivation based on the number of approving countries, GM crops, events, and traits in the last 23 y (1992–2014), rationale for approval, factors influencing approvals, and their implications in GM crop adoption. Results show that in 2014, there was an accumulative increase in the number of countries granting approvals at 29 (79% developing countries) for commercial cultivation and 31 (70% developing countries) for food and 19 (80% developing developing) for feed; 2012 had the highest number of approving countries and cultivation approvals; 2011 had the highest number of country approvals for feed, and 2014 for food approvals. Herbicide tolerance trait had the highest events approved, followed by insect tolerance traits. Approvals for food product quality increased in the second decade. Maize had the highest number of events approved (single and stacked traits), and stacked traits product gradually increased which is already 30% of the total trait approvals. These results may indicate understanding and acceptance of countries to enhance regulatory capability to be able to benefit from GM crop commercialization. Hence, the paper provided information on the trends on the growth of the GM crop industry in the last 23 y which may be vital in predicting future GM crops and traits. PMID:26039675

  4. Trends in global approvals of biotech crops (1992-2014).

    Science.gov (United States)

    Aldemita, Rhodora R; Reaño, Ian Mari E; Solis, Renando O; Hautea, Randy A

    2015-01-01

    With the increasing number of genetically modified (GM) events, traits, and crops that are developed to benefit the global population, approval of these technologies for food, feed, cultivation and import in each country may vary depending on needs, demand and trade interest. ISAAA established a GMO Approval Database to document global approvals of biotech crops. GM event name, crops, traits, developer, year of approval for cultivation, food/feed, import, and relevant dossiers were sourced from credible government regulatory websites and biosafety clearinghouses. This paper investigates the trends in GM approvals for food, feed and cultivation based on the number of approving countries, GM crops, events, and traits in the last 23 y (1992-2014), rationale for approval, factors influencing approvals, and their implications in GM crop adoption. Results show that in 2014, there was an accumulative increase in the number of countries granting approvals at 29 (79% developing countries) for commercial cultivation and 31 (70% developing countries) for food and 19 (80% developing developing) for feed; 2012 had the highest number of approving countries and cultivation approvals; 2011 had the highest number of country approvals for feed, and 2014 for food approvals. Herbicide tolerance trait had the highest events approved, followed by insect tolerance traits. Approvals for food product quality increased in the second decade. Maize had the highest number of events approved (single and stacked traits), and stacked traits product gradually increased which is already 30% of the total trait approvals. These results may indicate understanding and acceptance of countries to enhance regulatory capability to be able to benefit from GM crop commercialization. Hence, the paper provided information on the trends on the growth of the GM crop industry in the last 23 y which may be vital in predicting future GM crops and traits.

  5. The Cambridge Guide to the Solar System

    Science.gov (United States)

    Lang, Kenneth R.

    2003-10-01

    The Cambridge Guide to the Solar System provides a comprehensive, funamental, and up-to-date description of the solar system. It is written in a concise, light and uniform style, without being unnecessarily weighted down with specialized materials or the variable writing of multiple authors. It is filled with vital facts and information for astronomers of all types and for anyone with a scientific interest in the Earth, our Moon, all the other planets and their satellites, and related topics such as asteroids, comets, meteorites and meteors. The language, style, ideas and profuse illustrations will attract the general reader as well as professionals. A thorough report for general readers, it includes much compact reference data. Metaphors, similes and analogies will be of immense help to the lay person or non-science student, and they add to the enjoyment of the material. Vignettes containing historical, literary and even artistic material make this book unusual and interesting, and enhance its scientific content. Kenneth Lang is professor of astronomy in the Physics and Astronomy Department at Tufts University. He is the author of several astrophysics books, including The Sun from Space (Springer Verlag, 2000), Astrophysical Formulae: Radiation, Gas Processes, and High Energy Physics (Springer Verlag, 1999), Sun, Earth and Sky (Copernicus Books, 1997), Astrophysical Data: Planets and Stars (Springer Verlag, 1993), and Wanderers in Space: Exploration and Discovery in the Solar System (Cambridge, 1991),

  6. Firm Strategy and the Asian Advantage : The Case of the Emerging Biotech Industry

    OpenAIRE

    Umali, Celia L.

    2006-01-01

    Asia is considered by many to be the next biotech hub of the world as countries in the region are striving to develop the sector to be the next engine of growth of their respective economies. Recently many pharmacentical firms derive new products from the biotech sector. This paper on one hand examines the strategies pharmaceutical firms adopt to compete in the domestic and global market place and on the other hand evaluates the Asian advantages in terms of market and globalization drivers. F...

  7. Cambridge English First 2 audio CDs : authentic examination papers

    CERN Document Server

    2016-01-01

    Four authentic Cambridge English Language Assessment examination papers for the Cambridge English: First (FCE) exam. These examination papers for the Cambridge English: First (FCE) exam provide the most authentic exam preparation available, allowing candidates to familiarise themselves with the content and format of the exam and to practise useful exam techniques. The Audio CDs contain the recorded material to allow thorough preparation for the Listening paper and are designed to be used with the Student's Book. A Student's Book with or without answers and a Student's Book with answers and downloadable Audio are available separately. These tests are also available as Cambridge English: First Tests 5-8 on Testbank.org.uk

  8. Cambridge English First 2 with answers : authentic examination papers

    CERN Document Server

    2016-01-01

    Four authentic Cambridge English Language Assessment examination papers for the Cambridge English: First (FCE) exam. These examination papers for the Cambridge English: First (FCE) exam provide the most authentic exam preparation available, allowing candidates to familiarise themselves with the content and format of the exam and to practise useful exam techniques. The Student's Book is also available in a 'without answers' edition. Audio CDs (2) containing the exam Listening material and a Student's Book with answers and downloadable Audio are available separately. These tests are also available as Cambridge English: First Tests 5-8 on Testbank.org.uk

  9. The Whipple Museum and Cavendish Laboratory, Cambridge

    Science.gov (United States)

    Pippard, Brian

    The Whipple Museum is part of the History and Philosophy of Science Department in the University of Cambridge. It is on your right as soon as you enter Free School Lane from Pembroke Street, and is normally open between 1:30 and 4:30 P.M. on weekdays. The main room, a hall with hammer-beam roof, is a relic of Stephen Perse’s school (1624) now flourishing elsewhere in the city. It houses a large collection of mathematical, physical and astronomical instruments — abaci, Napier’s bones, slide rules; sextants and other surveying instruments; telescopes, compasses and pocket sundials (especially of ivory from Nuremberg 1500-1700); and a Grand Orrery by George Adams (1750). The gallery of a second room is used for special exhibitions, often of items from the well-stocked store. Some specialist catalogues have been compiled and are on sale.

  10. The Cambridge Illustrated History of Astronomy

    Science.gov (United States)

    Hoskin, Michael

    Expertly written and lavishly illustrated, The Cambridge Illustrated History of Astronomy offers a unique account of astronomical theory and practice from antiquity to the present day. How did Moslems of the Middle Ages use astronomy to calculate the direction of Mecca from far-flung corners of the Islamic world? Who was the only ancient Greek to suspect that the earth might revolve around the sun? How did Christopher Columbus abuse his knowledge of a lunar eclipse predicted by an astronomical almanac? Packed with anecdotes and intriguing detail, this book describes how we observed the sky and interpreted what we saw at different periods of history; how this influenced our beliefs and mythology; and how great astronomers contributed to what we now know. The result is a lively and highly visual history of astronomy - a compelling read for specialists and non-specialists alike.

  11. Cambridge Illustrated History of Archaeology, edited by Paul G. Bahn, Cambridge University Press, New York, 1996

    OpenAIRE

    Givens, Douglas R.

    1997-01-01

    The Cambridge Illustrated History of Archaeology is another in a series of volumes devoted to the history of archaeology that have appeared in recent time. Paul Bahn, the editor of the volume, has broken down his coverage of the history of worldwide archaeology into the following arrangement 'The Archaeology of Archaeology", "Old Worlds and New, 1500-1760", "Antiquarians and Explorers, 1760-1820", "Science and Romantic...

  12. Biotech/GM crops in horticulture: plum cv. HoneySweet resistant to plum pox virus

    Science.gov (United States)

    Commercialization of Biotech crops started in 1995. By 2011, genetically modified (GM) crops were grown world-wide on 160 million ha. Only 114.507 ha of GM crops were grown in Europe, of that, 114.490 ha were Bt maize and 17 ha were potato for industrial starch production. Currently, developing c...

  13. How Is Corporate Social Responsibility Addressed by Biotech Firms? a Case Study Analysis

    Science.gov (United States)

    Pérez-Bustamante, Guillermo

    2013-01-01

    This paper explores corporate social responsibility (CSR) in the biotech high-tech sector as a way to achieve competitive advantages. After presenting the importance of science for high-tech firms, the paper focuses on the social and economic role of CSR. Next, the primary reasons for firms' engagement in CSR activities are presented, followed by…

  14. 76 FR 42682 - China Biotech Life Sciences Trade Mission-Clarification and Amendment

    Science.gov (United States)

    2011-07-19

    ... DEPARTMENT OF COMMERCE International Trade Administration China Biotech Life Sciences Trade... Life Science Trade Mission to China, 76 FR 17,621, Mar. 30, 2011, to clarify eligibility and amend the... representatives from a variety of U.S. biotechnology and life science firms and trade organizations. In response...

  15. Screening DNA chip and event-specific multiplex PCR detection methods for biotech crops.

    Science.gov (United States)

    Lee, Seong-Hun

    2014-11-01

    There are about 80 biotech crop events that have been approved by safety assessment in Korea. They have been controlled by genetically modified organism (GMO) and living modified organism (LMO) labeling systems. The DNA-based detection method has been used as an efficient scientific management tool. Recently, the multiplex polymerase chain reaction (PCR) and DNA chip have been developed as simultaneous detection methods for several biotech crops' events. The event-specific multiplex PCR method was developed to detect five biotech maize events: MIR604, Event 3272, LY 038, MON 88017 and DAS-59122-7. The specificity was confirmed and the sensitivity was 0.5%. The screening DNA chip was developed from four endogenous genes of soybean, maize, cotton and canola respectively along with two regulatory elements and seven genes: P35S, tNOS, pat, bar, epsps1, epsps2, pmi, cry1Ac and cry3B. The specificity was confirmed and the sensitivity was 0.5% for four crops' 12 events: one soybean, six maize, three cotton and two canola events. The multiplex PCR and DNA chip can be available for screening, gene-specific and event-specific analysis of biotech crops as efficient detection methods by saving on workload and time. © 2014 Society of Chemical Industry. © 2014 Society of Chemical Industry.

  16. Recent Developments in Cambridge College Libraries

    Directory of Open Access Journals (Sweden)

    Alison Wilson

    2006-07-01

    Full Text Available Cambridge University has three tiers of libraries available to students: the University Library, departmental (subject libraries and college libraries. Over the past thirty years there has been increasing pressure on the colleges to provide more books, reader places and technical resources in their libraries, with the result that a number of new library buildings, of very different styles, have been opened. Other colleges have opted for refurbishment and extension of existing libraries. These libraries are small (30-100,000 books and intimate, often open 24 hours a day and with generous provision for lending books. Great importance is placed on keeping them at the heart of the college. Challenges for architects are the sensitive sites, restrictions on changes to listed buildings, and the limited space available. The constricted sites cause difficulties for the builders too. I will consider some solutions to these problems with reference to projects in four colleges: Pembroke, Peterhouse, Corpus Christi and Newnham. At Pembroke architects Freeland Rees Roberts have built an extension to a listed building and at Peterhouse they have adapted an adjoining room. Corpus Christi is moving its library to a Victorian building which has been internally redesigned by Wright + Wright. Newnham demolished a 1960s extension in order to develop the plot more efficiently to a design by John Miller + Partners. All the architects have shown sensitivity to the needs of their clients and ingenuity in making intensive use of limited space.

  17. Cambridge Marketing College - interview about e-commerce

    OpenAIRE

    Paa-Kerner, Greta; Cambridge Marketing College

    2015-01-01

    Interview about e-commerce.\\ud \\ud The Cambridge Marketing College interviews Greta Paa-Kerner to learn about the dynamic world of e-commerce. She discusses online retail trends and shopping influencers.

  18. Parameters of Regional Cooperative Behavior in the German Biotech Industry – A Quantitative Social Network Analysis

    DEFF Research Database (Denmark)

    Mitze, Timo; Strotebeck, Falk

    We analyse the determinants of network formation in Germany’s biotechnology industry using social network analysis combined with a regression approach for count data. Outcome variable of interest is the degree centrality of German regions, which is specified as a function of the region’s innovative...... and economic performance as well as biotech-related policy variables. The inclusion of the latter allows us to shed new light on the question to what extent R&D-based cluster policies are able to impact on the formation of the German biotech network. Our results show that policy indicators such as the volume...... of public funding for collaborative R&D activity are positively correlated with the region’s overall and interregional degree centrality. However, besides this direct funding effect, we do not observe any further (non-pecuniary) advantages such as prestige or image effects. Regarding the role played...

  19. Knowledge management in the QbD paradigm: manufacturing of biotech therapeutics.

    Science.gov (United States)

    Herwig, Christoph; Garcia-Aponte, Oscar F; Golabgir, Aydin; Rathore, Anurag S

    2015-07-01

    In the quality by design (QbD) paradigm, global regulatory agencies have introduced the concepts of quality risk management and knowledge management (KM) as enablers for an enhanced pharmaceutical quality system. Although the concept of quality risk management has been well elucidated in the literature, the topic of KM has received relatively scant attention. In this paper we present an opinion on KM in the QbD paradigm as it relates to the manufacturing of biotech therapeutic products. Both academic and industrial viewpoints have been considered and key gaps have been elucidated. The authors conclude that there is an urgent need for the biotech industry to create efficient KM approaches if they wish to be successful in QbD implementation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Open Data for Research and Strategic Monitoring in the Pharmaceutical and Biotech Industry

    Directory of Open Access Journals (Sweden)

    Baldissera Giovani

    2017-04-01

    Full Text Available Open data is considered the new oil. As oil can be used to produce fertilisers, pesticides, lubricants, plastics and many other derivatives, so data is considered the commodity to use and re-use to create value. The number of initiatives supporting free access to data has increased in the last years and open data is becoming the norm in the public sector; the approach empowers stakeholders and nurtures the economy. Even if at early stage, private companies also are adapting to the open data market. A survey was conducted to which thirteen companies of different size (from micro enterprises to world-leading pharmas in the pharmaceutical and biotech sector and representing four business models archetypes of companies exploiting open data (aggregators, developers, enrichers and enablers participated. The information collected provides a snapshot of the use of open data by the pharmaceutical and biotech industry in 2015–2016. The companies interviewed use open data to complement proprietary data for research purposes, to implement licensing-in/licensing-out strategies, to map partnerships and connections among players or to identify key expertise and hire staff. Pharmaceutical and biotech companies have made of the protection of knowledge a dogma at the foundation of their business models, but using and contributing to the open data movement may change their approach to intellectual property and innovation.

  1. Michele Renee Salzman, Marvina A. Sweeney & William Adler (eds., The Cambridge History of Religions in the Ancient World (2 vols. (New York: Cambridge University Press, 2013

    Directory of Open Access Journals (Sweden)

    Giorgio Baruchello

    2014-03-01

    Full Text Available Review of: Michele Renee Salzman, Marvina A. Sweeney & William Adler (eds., The Cambridge History of Religions in the Ancient World (2 vols. (New York: Cambridge University Press, 2013

  2. 8th Cambridge Workshop on Universal Access and Assistive Technology

    CERN Document Server

    Lazar, Jonathan; Heylighen, Ann; Dong, Hua

    2016-01-01

    This book presents the proceedings of the 8th Cambridge Workshop on Universal Access and Assistive Technology (CWUAAT '14), incorporating the 11th Cambridge Workshop on Rehabilitation Robotics, held in Cambridge, England in March 2016. It presents novel and state-of-the-art research from an international group of leaders in the fields of universal access and assistive technology. It explores various issues including the reconciliation of usability, accessibility and inclusive design, the design of inclusive assistive and rehabilitation systems, measuring product demand and human capabilities, data mining and visualizing inclusion, legislation in inclusive design, and situational inclusive interfaces (automotive and aerospace). This book provides an invaluable resource to researchers, postgraduates, design practitioners, therapists and clinical practitioners, as well as design teachers.

  3. Cambridge Illustrated History of Archaeology, edited by Paul G. Bahn, Cambridge University Press, New York, 1996

    Directory of Open Access Journals (Sweden)

    Douglas R. Givens

    1997-11-01

    Full Text Available The Cambridge Illustrated History of Archaeology is another in a series of volumes devoted to the history of archaeology that have appeared in recent time. Paul Bahn, the editor of the volume, has broken down his coverage of the history of worldwide archaeology into the following arrangement 'The Archaeology of Archaeology", "Old Worlds and New, 1500-1760", "Antiquarians and Explorers, 1760-1820", "Science and Romanticism, 1820-1860", "The Search for Human Origins, 1860-1920", "Archaeology Comes of Age, 1920-1960", "New Techniques and Competing Philosophies, 1960-1990",and "Current Controversies and Future Trends". Bahn's volume explores many of the major developments in archaeological practice from both in the classical world and was as from the practice of archaeology in the Americas. The volume even gives the reader a glimpse into the origins and growth of archaeology in New Zealand. Of particular interest is coverage of the history of early archaeological efforts having to do with early studies of human origins.

  4. Biotech crops: imperative for achieving the millenium development goals and sustainability of agriculture in the climate change era.

    Science.gov (United States)

    Husaini, Amjad M; Tuteja, Narendra

    2013-01-01

    Biotechnological intervention in the development of crops has opened new vistas in agriculture. Central to the accomplishment of the Millennium Development Goals (MDGs), biotech-agriculture is essential in meeting these targets. Biotech crops have already made modest contributions toward ensuring food and nutrition security by reducing losses and increasing productivity, with less pesticide input. These crops could help address some of the major challenges in agriculture-based economies created by climate change. Projections of global climate change expect the concentration of greenhouse gases to increase, aridization of the environment to increase, temperature fluctuations to occur sharply and frequently, and spatial and temporal distribution of rainfall to be disturbed-all of which will increase abiotic stress-related challenges to crops. Countering these challenges and to meet the food requirement of the ever-increasing world population (expected to reach 9 billion by 2030) we need to (1) develop and use biotech crops for mitigating adverse climatic changes; (2) develop biotech crops resilient to adverse environmental conditions; and (3) address the issues/non-issues raised by NGO's and educate the masses about the benefits of biotech crops.

  5. Growth and profitability in small privately held biotech firms: preliminary findings.

    Science.gov (United States)

    Brännback, Malin; Carsrud, Alan; Renko, Maija; Ostermark, Ralf; Aaltonen, Jaana; Kiviluoto, Niklas

    2009-06-01

    This paper reports on preliminary findings on a study of the relationship of growth and profitability among small privately held Finnish Life Science firms. Previous research results concerning growth and profitability are mixed, ranging from strongly positive to a negative relationship. The conventional wisdom states that growth is a prerequisite for profitability. Our results suggest that the reverse is the case. A high profitability-low growth biotech firm is more probably to make the transition to high profitability-high growth than a firm that starts off with low profitability and high growth.

  6. [Probability, Cambridge Conference on School Mathematics Feasibility Study No. 7.

    Science.gov (United States)

    Davis, R.

    These materials were written with the aim of reflecting the thinking of the Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics. They represent a practical response to a proposal by CCSM that some elements of probability be introduced in the elementary grades. These materials provide children…

  7. [Cambridge Conference on School Mathematics Feasibility Studies 9-13.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    These materials are a part of a series of studies sponsored by the Cambridge Conference on School Mathematics which reflects the ideas of CCSM regarding the goals and objectives for school mathematics K-12. Feasibility Studies 9-13 contain a wide range of topics. The following are the titles and brief descriptions of these studies. Number…

  8. 76 FR 12729 - Cambridge Environmental Inc; Transfer of Data

    Science.gov (United States)

    2011-03-08

    ... number, [EP-W-11-020], Cambridge Environmental Inc., will review, evaluate a portion of a risk assessment... assessment, and the soundness of the conclusions. Develop and enhance risk assessment methods and tools which... recommending improvements to existing tools and methods, or investigating issues related to the risk assessment...

  9. Evolution of physics examining 1940-2000 at Cambridge

    Science.gov (United States)

    Roberts, A.; Brown, L. M.

    2001-07-01

    Much controversy exists about the supposed changing examination standards. Emphasis has been placed on the standards of GCSE and A-level examinations. However, many large employers recruit graduates, and so university examination standards also deserve attention. Here, Cambridge University Part II (third year undergraduate) examinations in Physics are studied since 1940. Trends in prescriptiveness, choice of questions, and other variables were found.

  10. Solid lipid nanoparticles for hydrophilic biotech drugs: optimization and cell viability studies (Caco-2 & HEPG-2 cell lines)

    Czech Academy of Sciences Publication Activity Database

    Severino, P.; Andreani, T.; Jäger, Alessandro; Chaud, M. V.; Santana, M. H. A.; Silva, A. M.; Souto, E. B.

    2014-01-01

    Roč. 81, 23 June (2014), s. 28-34 ISSN 0223-5234 R&D Projects: GA ČR GAP208/10/1600 Institutional support: RVO:61389013 Keywords : lipid nanoparticles * double emulsion * hydrophilic biotech drugs Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.447, year: 2014

  11. University of Cambridge deploys Procket Networks' PRO/8801

    CERN Multimedia

    2003-01-01

    Procket Networks, a provider of high performance Internet Protocol (IP) technology and products has announced that the University of Cambridge has deployed the PRO/8801(TM) router into its research network to develop industry-leading deep packet inspection applications. The major application for this deployment is to identify and understand new traffic patterns created by large scale scientific computations and downloads such as the GRID (1 page).

  12. Philosophy at Cambridge, Newsletter of the Faculty of Philosophy

    OpenAIRE

    Lecky-Thompson, Jenni

    2009-01-01

    Philosophy Newsletter. Articles by: Edward Craig - From the Chairman. Onora O'Neill - "It's the newspapers I can't stand. Serena Olsaretti - The 2004 Annual Royal Institute of Philosophy Conference. Mary Leng - Mathematical Knowledge Conference. Postgraduate Conference. Jane Heal - Facts, Fables and Funds. Hugh Mellor - Uses and Abuses of Probability. Amanda Boyle - Nobody Knows Anything: Philosophy, Film and Me. Jaime Whyte - Seven Years at Cambridge Alex Oliver...

  13. Capacity optimization and scheduling of a multiproduct manufacturing facility for biotech products.

    Science.gov (United States)

    Shaik, Munawar A; Dhakre, Ankita; Rathore, Anurag S; Patil, Nitin

    2014-01-01

    A general mathematical framework has been proposed in this work for scheduling of a multiproduct and multipurpose facility involving manufacturing of biotech products. The specific problem involves several batch operations occurring in multiple units involving fixed processing time, unlimited storage policy, transition times, shared units, and deterministic and fixed data in the given time horizon. The different batch operations are modeled using state-task network representation. Two different mathematical formulations are proposed based on discrete- and continuous-time representations leading to a mixed-integer linear programming model which is solved using General Algebraic Modeling System software. A case study based on a real facility is presented to illustrate the potential and applicability of the proposed models. The continuous-time model required less number of events and has a smaller problem size compared to the discrete-time model. © 2014 American Institute of Chemical Engineers.

  14. Cambridge IGCSE and international certificate French foreign language

    CERN Document Server

    Grime, Yvette; Thacker, Mike

    2013-01-01

    This brand-new Student Book provides a grammar-led approach with extensive exam preparation that will help you develop independent, culturally aware students of French ready for the exam. The book is written to the latest Cambridge International Examinations syllabus by experienced teachers. Extensive use of French reflects the style of the exams and, with specific advice and practice, it helps students use the acquired skills to their best ability. Topics on Francophone cultures are integrated throughout to ensure students gain the cultural awareness that is at the heart of this qualification

  15. Applications of the Cambridge Structural Database in chemical education1

    Science.gov (United States)

    Battle, Gary M.; Ferrence, Gregory M.; Allen, Frank H.

    2010-01-01

    The Cambridge Structural Database (CSD) is a vast and ever growing compendium of accurate three-dimensional structures that has massive chemical diversity across organic and metal–organic compounds. For these reasons, the CSD is finding significant uses in chemical education, and these applications are reviewed. As part of the teaching initiative of the Cambridge Crystallographic Data Centre (CCDC), a teaching subset of more than 500 CSD structures has been created that illustrate key chemical concepts, and a number of teaching modules have been devised that make use of this subset in a teaching environment. All of this material is freely available from the CCDC website, and the subset can be freely viewed and interrogated using WebCSD, an internet application for searching and displaying CSD information content. In some cases, however, the complete CSD System is required for specific educational applications, and some examples of these more extensive teaching modules are also discussed. The educational value of visualizing real three-dimensional structures, and of handling real experimental results, is stressed throughout. PMID:20877495

  16. The Cambridge Structural Database in retrospect and prospect.

    Science.gov (United States)

    Groom, Colin R; Allen, Frank H

    2014-01-13

    The Cambridge Crystallographic Data Centre (CCDC) was established in 1965 to record numerical, chemical and bibliographic data relating to published organic and metal-organic crystal structures. The Cambridge Structural Database (CSD) now stores data for nearly 700,000 structures and is a comprehensive and fully retrospective historical archive of small-molecule crystallography. Nearly 40,000 new structures are added each year. As X-ray crystallography celebrates its centenary as a subject, and the CCDC approaches its own 50th year, this article traces the origins of the CCDC as a publicly funded organization and its onward development into a self-financing charitable institution. Principally, however, we describe the growth of the CSD and its extensive associated software system, and summarize its impact and value as a basis for research in structural chemistry, materials science and the life sciences, including drug discovery and drug development. Finally, the article considers the CCDC's funding model in relation to open access and open data paradigms. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Recombinant DNA in Cambridge: lessons for nuclear energy

    International Nuclear Information System (INIS)

    Federow, H.

    1977-09-01

    The 1976 experience of Cambridge, Massachusetts, in settling the recombinant DNA research issue is unique in recent history as the first instance of essentially lay panels judging the conduct of scientific research. Furthermore, because the panel was composed of citizens who would be affected by the research, the experience suggests a model for conflict resolution in other areas of public controversy. With one of these, nuclear energy, the controversy has two important points in common: although the primary burden of any accident would be borne by the local community, benefits of the DNA research or reactor operation accrue to a much broader range of people; and in both issues there is a need to resolve the question, ''How safe is safe enough.'' It is therefore proposed that a panel similar to the Cambridge one could be established to deal with the controversy surrounding a proposed nuclear plant. In any community where there was such controversy, a panel could be convened to assess whether the plant was acceptable to that community. Such a panel would be composed of members of the community who were not affected directly by the plant. It would also have to have a restricted range of inquiry, oriented toward the specifics of the proposed plant. Such a plant review panel, under properly designed procedures, could change the licensing process to one concerned solely with safety and provide an appropriate forum for issues concerning the acceptability of nuclear power

  18. Sediment remediation of the Hespeler Mill Pond, Cambridge, Ontario

    Energy Technology Data Exchange (ETDEWEB)

    Angeloni, D.; Eby, M.; Jarvis, S.; Martin, P. [Univ. of Guelph, School of Engineering, Guelph, Ontario (Canada)]. E-mail: danielle.angeloni@earthtech.ca

    2002-06-15

    'Full text:' Low dissolved oxygen levels and large accumulated sediment remediation alternatives were examined to assemble the Hespeler Mill Pond, Cambridge (HMP) into a healthier and more desirable recreational area in the City of Cambridge. The theory that a large amount of sediment has been deposited into the HMP from the Speed River upstream over a number of years predicts the depressed oxygen levels, high nutrient-loading rates and the odour problems in the summer months. The initial phase in the remediation plan for this project involved extensive background research and investigation. The focus was on determining the characteristics of the sediment and the history of the pond, to ultimately decide if the sediment was the source of the issues. Dissolved oxygen field tests and sediment sampling were conducted to get information on the magnitude of the problem and the environmental hazards potentially present in the pond. The pond was modelled utilising the Streeter-Phelps oxygen-sag model to predict the oxygen deficit. Biochemical Oxygen Demand (BOD{sub 5}) testing was completed to determine the oxygen demand in the pond. These tests were conducted by using water samples obtained from various sample points at the pond. The proposed solution is a combined dredging and aeration approach. Mechanical dredging using a clamshell bucket and the installation of aerators is expected to solve the dissolved oxygen and water quality issues. (author)

  19. Exzellenz in der Bildung für eine innovative Schweiz: Die Position des Wirtschaftsdachverbandes Chemie Pharma Biotech.

    Science.gov (United States)

    Sennhauser, Marcel

    2018-02-01

    In Switzerland, the chemical, pharma and biotech industries make a substantial and sustained contribution to the Swiss economy. The company members of scienceindustries employ around 70,000 people in Switzerland. Since 1980 value creation and productivity have increased markedly. As a result the share of the Swiss gross value added has grown continually to reach 5.6% in 2015. Exports have also increased. Today the chemical, pharma and biotech industry contributes around 45% of all Swiss exports and is therefore the largest Swiss export industry. This article describes the key requirements from the viewpoint of the chemical-pharma industry in order that Switzerland can continue to compete as an innovative location in global competition.

  20. What Will Be the Benefits of Biotech Wheat for European Agriculture?

    Science.gov (United States)

    Ricroch, Agnès E

    2017-01-01

    In European countries, wheat occupies the largest crop area with high yielding production. France, a major producer and exporter in Europe, ranks the fifth producer worldwide. Biotic stresses are European farmers' major challenges (fungal and viral diseases, and insect pests) followed by abiotic ones such as drought and grain protein composition. During the last 40 years, 1136 scientific articles on biotech wheat were published by USA followed by China, Australia, Canada, and European Union with the UK. European research focuses on pests and diseases resistances using widely marker-assisted selection (MAS). Transgenesis is used in basic research to develop resistance against some fungi (Fusarium head blight) while RNA interference (RNAi) silencing is used against some fungi and virus. Transgenic plants were also transformed with genes from various species for drought tolerance. The UK (mostly with transgenesis and site-specific nucleases) and France (with no transgenic tools but with MAS and site-specific nucleases) are the main countries carrying out research programs for both biotic stress and drought tolerance. Thus, few European countries used transgenesis for gluten protein composition and RNAi-mediated silencing in celiac disease. Because of vandalism field trials of transgenics dropped since 2000. No transgenic wheat is cultivated in Europe for political reasons.

  1. Trait stacking for biotech crops: an essential consideration for agbiotech development projects for building trust

    Directory of Open Access Journals (Sweden)

    Ezezika Obidimma C

    2012-05-01

    Full Text Available Abstract The development of agricultural biotechnology humanitarian projects for food security in the last five years has been rapid in developing countries and is expected to rise sharply over the coming years. An extremely critical issue in these projects involves building trust with the community and farmers they aim to serve. For the first time, our social audit engagement with one of these initiatives, the Water Efficient Maize for Africa project, has revealed that a critical but unrecognized component of building trust with farmers involves publicly addressing the concerns surrounding stacked trait crops. As a result, we argue in this article that it is critical to actively anticipate the concerns that could be raised over trait stacking by incorporating them into global access plans of such initiatives early in order to facilitate adoption, provide the best value to the small-scale farmer and gain trust with the community whom these projects aim to serve. This perspective, based on an actual international social audit, should be of value to scientists, funders and partners involved in biotech development initiatives for food security.

  2. A history of plant biotechnology: from the Cell Theory of Schleiden and Schwann to biotech crops.

    Science.gov (United States)

    Vasil, Indra K

    2008-09-01

    Plant biotechnology is founded on the principles of cellular totipotency and genetic transformation, which can be traced back to the Cell Theory of Matthias Jakob Schleiden and Theodor Schwann, and the discovery of genetic transformation in bacteria by Frederick Griffith, respectively. On the 25th anniversary of the genetic transformation of plants, this review provides a historical account of the evolution of the theoretical concepts and experimental strategies that led to the production and commercialization of biotech (transformed or transgenic) plants expressing many useful genes, and emphasizes the beneficial effects of plant biotechnology on food security, human health, the environment, and conservation of biodiversity. In so doing, it celebrates and pays tribute to the contributions of scores of scientists who laid the foundation of modern plant biotechnology by their bold and unconventional thinking and experimentation. It highlights also the many important lessons to be learnt from the fascinating history of plant biotechnology, the significance of history in science teaching and research, and warns against the danger of the growing trends of ignoring history and historical illiteracy.

  3. 7th Cambridge Workshops on Universal Access and Assistive Technology

    CERN Document Server

    Lazar, J; Heylighen, A; Dong, H; Inclusive Designing : Joining Usability, Accessibility, and Inclusion

    2014-01-01

    ‘Inclusive Designing’ presents the proceedings of the seventh Cambridge Workshop on Universal Access and Assistive Technology (CWUAAT '14). It represents a unique multi-disciplinary workshop for the Inclusive Design Research community where designers, computer scientists, engineers, architects, ergonomists, policymakers and user communities can exchange ideas. The research presented at CWUAAT '14 develops methods, technologies, tools and guidance that support product designers and architects to design for the widest possible population for a given range of capabilities, within a contemporary social and economic context. In the context of developing demographic changes leading to greater numbers of older people and people with disabilities, the general field of Inclusive Design Research strives to relate the capabilities of the population to the design of products. Inclusive populations of older people contain a greater variation in sensory, cognitive and physical user capabilities. These variations may be...

  4. Next biotech plants: new traits, crops, developers and technologies for addressing global challenges.

    Science.gov (United States)

    Ricroch, Agnès E; Hénard-Damave, Marie-Cécile

    2016-08-01

    Most of the genetically modified (GM) plants currently commercialized encompass a handful of crop species (soybean, corn, cotton and canola) with agronomic characters (traits) directed against some biotic stresses (pest resistance, herbicide tolerance or both) and created by multinational companies. The same crops with agronomic traits already on the market today will continue to be commercialized, but there will be also a wider range of species with combined traits. The timeframe anticipated for market release of the next biotech plants will not only depend on science progress in research and development (R&D) in laboratories and fields, but also primarily on how demanding regulatory requirements are in countries where marketing approvals are pending. Regulatory constraints, including environmental and health impact assessments, have increased significantly in the past decades, delaying approvals and increasing their costs. This has sometimes discouraged public research entities and small and medium size plant breeding companies from using biotechnology and given preference to other technologies, not as stringently regulated. Nevertheless, R&D programs are flourishing in developing countries, boosted by the necessity to meet the global challenges that are food security of a booming world population while mitigating climate change impacts. Biotechnology is an instrument at the service of these imperatives and a wide variety of plants are currently tested for their high yield despite biotic and abiotic stresses. Many plants with higher water or nitrogen use efficiency, tolerant to cold, salinity or water submergence are being developed. Food security is not only a question of quantity but also of quality of agricultural and food products, to be available and accessible for the ones who need it the most. Many biotech plants (especially staple food) are therefore being developed with nutritional traits, such as biofortification in vitamins and metals. The main

  5. Insect-resistant biotech crops and their impacts on beneficial arthropods

    Science.gov (United States)

    Gatehouse, A. M. R.; Ferry, N.; Edwards, M. G.; Bell, H. A.

    2011-01-01

    With a projected population of 10 billion by 2050, an immediate priority for agriculture is to achieve increased crop yields in a sustainable and cost-effective way. The concept of using a transgenic approach was realized in the mid-1990s with the commercial introduction of genetically modified (GM) crops. By 2010, the global value of the seed alone was US $11.2 billion, with commercial biotech maize, soya bean grain and cotton valued at approximately US $150 billion. In recent years, it has become evident that insect-resistant crops expressing δ-endotoxin genes from Bacillus thuringiensis have made a significant beneficial impact on global agriculture, not least in terms of pest reduction and improved quality. However, because of the potential for pest populations to evolve resistance, and owing to lack of effective control of homopteran pests, alternative strategies are being developed. Some of these are based on Bacillus spp. or other insect pathogens, while others are based on the use of plant- and animal-derived genes. However, if such approaches are to play a useful role in crop protection, it is desirable that they do not have a negative impact on beneficial organisms at higher trophic levels thus affecting the functioning of the agro-ecosystem. This widely held concern over the ecological impacts of GM crops has led to the extensive examination of the potential effects of a range of transgene proteins on non-target and beneficial insects. The findings to date with respect to both commercial and experimental GM crops expressing anti-insect genes are discussed here, with particular emphasis on insect predators and parasitoids. PMID:21444317

  6. Insect-resistant biotech crops and their impacts on beneficial arthropods.

    Science.gov (United States)

    Gatehouse, A M R; Ferry, N; Edwards, M G; Bell, H A

    2011-05-12

    With a projected population of 10 billion by 2050, an immediate priority for agriculture is to achieve increased crop yields in a sustainable and cost-effective way. The concept of using a transgenic approach was realized in the mid-1990s with the commercial introduction of genetically modified (GM) crops. By 2010, the global value of the seed alone was US $11.2 billion, with commercial biotech maize, soya bean grain and cotton valued at approximately US $150 billion. In recent years, it has become evident that insect-resistant crops expressing δ-endotoxin genes from Bacillus thuringiensis have made a significant beneficial impact on global agriculture, not least in terms of pest reduction and improved quality. However, because of the potential for pest populations to evolve resistance, and owing to lack of effective control of homopteran pests, alternative strategies are being developed. Some of these are based on Bacillus spp. or other insect pathogens, while others are based on the use of plant- and animal-derived genes. However, if such approaches are to play a useful role in crop protection, it is desirable that they do not have a negative impact on beneficial organisms at higher trophic levels thus affecting the functioning of the agro-ecosystem. This widely held concern over the ecological impacts of GM crops has led to the extensive examination of the potential effects of a range of transgene proteins on non-target and beneficial insects. The findings to date with respect to both commercial and experimental GM crops expressing anti-insect genes are discussed here, with particular emphasis on insect predators and parasitoids.

  7. Investigating the Impact of Cambridge International Assessments on U.S. Stakeholders: Student and Teacher Perceptions

    Science.gov (United States)

    Shaw, Stuart

    2011-01-01

    As part of the continuing program to study the impact of its international assessments, the University of Cambridge International Examinations ("Cambridge") has undertaken a series of studies investigating the impact on a range of US stakeholders. This paper reports on research designed to respond to a series of washback and impact…

  8. Assessing the Impact of Arts and Humanities Research at the University of Cambridge. Technical Report

    Science.gov (United States)

    Levitt, Ruth; Celia, Claire; Diepeveen, Stephanie; Chonaill, Siobhan Ni; Rabinovich, Lila; Tiessen, Jan

    2010-01-01

    This project for the University of Cambridge and the Arts and Humanities Research Council (AHRC) assesses the impacts of arts and humanities research at the University of Cambridge. Evidence from interviews, a survey of research staff and detailed case studies indicates that these disciplines already have a broad range of impacts. Many of these…

  9. Geometry Report; Cambridge Conference on School Mathematics Feasibility Study No. 39.

    Science.gov (United States)

    Stolzenberg, Gabriel

    These materials were written with the aim of reflecting the thinking of the Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics. This report deals with some seventh grade mathematical concepts taught at Cambridge Friends' School. The discovery approach was utilized by the teacher in order to…

  10. The 'Naturals' and Victorian Cambridge: Reflections on the Anatomy of an Elite, 1851-1914.

    Science.gov (United States)

    MacLeod, Roy; Moseley, Russell

    1980-01-01

    Explores how graduates of Cambridge University from 1851-1914 contributed expertise gained during their university years to British society, particularly the public sector in which they occupied many important positions. The term 'Naturals' refers to those who passed final exams in natural sciences and mathematics at Cambridge. (Author/DB)

  11. Anneli Randla kaitses doktorikraadi Cambridge'is / Anneli Randla ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Randla, Anneli, 1970-

    1999-01-01

    5. mail kaitses Cambridge'is esimese eesti kunstiteadlasena doktorikraadi Anneli Randla. Töö teema: kerjusmungaordukloostrite arhitektuur Põhja-Euroopas. Juhendaja dr. Deborah Howard. Doktorikraadile esitatavatest nõudmistest, doktoritöö kaitsmisest, magistrikraadi kaitsnu õppimisvõimalustest Cambridge's.

  12. Cambridge Polytrauma Pathway: Are we making appropriately guided decisions?

    Science.gov (United States)

    Wynell-Mayow, William; Guevel, Borna; Quansah, Benjamin; O'Leary, Ronan; Carrothers, Andrew D

    2016-10-01

    Addenbrooke's Hospital, the Major Trauma Centre for the East of England Trauma Network, received 1070 major trauma patients between 1st January and 31st December 2014. In order to improve care, an audit was performed of 59 patients meeting our own selection criteria for orthopaedic polytrauma between 1st January 2013 and 31st December 2013. The Cambridge Polytrauma Pathway was devised through NCEPOD guidelines, literature review, internal and external discussion. It facilitates provision of best practice Early Appropriate Care, encompassing - multidisciplinary consultant decisions around the patient in our Neurological and Trauma Critical Care Unit, early full body trauma CT scans, serial measurements of lactate and fibrinogen levels, and out-of-hours orthopaedic theatre reserved for life-and-limb threatening injuries. Re-audit was conducted of 15 patients meeting selection criteria, admitted between 1st October 2014 and 31st March 2015. Significant improvements in recording of lactate and fibrinogen were demonstrated, both on admission (lactate - ppolytrauma patients and it is recommended that either the GOS-E, or the EQ-5D scoring systems be introduced to assess this. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  13. Findings from the Harvard Medical School Cambridge Integrated Clerkship, a Year-Long Longitudinal Psychiatry Experience.

    Science.gov (United States)

    Cheng, Elisa; Hirsh, David; Gaufberg, Elizabeth; Griswold, Todd; Wesley Boyd, J

    2018-06-01

    The Harvard Medical School Cambridge Integrated Clerkship is a longitudinal integrated clerkship that has provided an alternative clinical model for medical education in psychiatry since its inception in 2004. This study was undertaken in an effort to better understand the student experience of the Cambridge Integrated Clerkship and how it may have impacted students' perceptions of and interest in psychiatry, as well as performance. Qualitative surveys were sent via e-mail to the first 11 student cohorts who had completed the Cambridge Integrated Clerkship (from 2004 to 2014) and for whom we had e-mail addresses (N = 100), and the free-text responses were coded thematically. All available standardized scoring data and residency match data for Cambridge Integrated Clerkship graduates were obtained. From 2006 to 2014, 12 out of 73 Cambridge Integrated Clerkship students who entered the match chose a psychiatry residency (16.4%), four times more than students in traditional clerkships at Harvard Medical School (3.8% of 1355 students) or the national average (4.1% of 146,066 US applicants). Thirty of the 100 surveyed Cambridge Integrated Clerkship graduates (30%) responded to the qualitative survey with free-text remarks on a number of themes. Cambridge Integrated Clerkship students compared positively to their classmates in terms of standardized test performance. Their fourfold higher match rate into psychiatry compared to other students raises intriguing questions as to what role a longitudinal clerkship might have played in developing interest in psychiatry as a career.

  14. Judicial activism, the Biotech Directive and its institutional implications – Is the Court acting as a legislator or a court when defining the ‘human embryo’?

    DEFF Research Database (Denmark)

    Faeh, Andrea Beata

    2015-01-01

    The Court of Justice of the European Union (Court) delivered a preliminary ruling in 2011 in the case of Oliver Brüstle v Greenpeace on the interpretation of Article 6(2) of the Biotech Directive and thereby established an autonomous concept of the term ‘human embryo’. The Brüstle decision raises...

  15. Explaining ICT Infrastructure and E-Commerce Uses and Benefits in Industrial Clusters-Evidence from a Biotech Cluster

    DEFF Research Database (Denmark)

    Scupola, Ada; Steinfield, Charles

    2006-01-01

    in an industrial cluster might utilize and derive benefit from a public, broadband ICT infrastructure, particularly in support of e-commerce applications. A case study of a successful biotech cluster in Denamrk and Sweden-The Medicon Valley-provides a preliminary test of these expectations. Distinctions in uses...... and benefits based upon firm size are considered. A key finding is that small firms that would not otherwise be expected to gain from global e-commerce can rely on the cluster "brand" to enable trade with unknown and distant partners.......The literature on Industrial Clusters has not focused heavely on the role of the ICT infrastructure, nor on the potentail implications of electronic commerce. In this paper, we examine the theoretical bases for bringing these research streams together, and develop expectations for how firms...

  16. An Improved Cambridge Filter Pad Extraction Methodology to Obtain More Accurate Water and “Tar” Values: In Situ Cambridge Filter Pad Extraction Methodology

    OpenAIRE

    Ghosh David; Jeannet Cyril

    2014-01-01

    Previous investigations by others and internal investigations at Philip Morris International (PMI) have shown that the standard trapping and extraction procedure used for conventional cigarettes, defined in the International Standard ISO 4387 (Cigarettes -- Determination of total and nicotine-free dry particulate matter using a routine analytical smoking machine), is not suitable for high-water content aerosols. Errors occur because of water losses during the opening of the Cambridge filter p...

  17. Brief history of the Cambridge STEM aberration correction project and its progeny

    Energy Technology Data Exchange (ETDEWEB)

    Brown, L. Michael [Cavendish Laboratory, University of Cambridge, J.J. Thomson Avenue, Cambridge CB3 0HE (United Kingdom); Batson, Philip E. [Institute for Advanced Materials, Devices and Nanotechnology, Rutgers University, Piscataway, NJ 08854 (United States); Department of Physics, Rutgers University, Piscataway, NJ 08854 (United States); Department of Materials Science, Rutgers University, Piscataway, NJ 08854 (United States); Dellby, Niklas [Nion Company, 11515 NE 118th Street, Kirkland, WA 98034 (United States); Krivanek, Ondrej L. [Nion Company, 11515 NE 118th Street, Kirkland, WA 98034 (United States); Department of Physics, Arizona State University, Tempe, AZ 85287 (United States)

    2015-10-15

    We provide a brief history of the project to correct the spherical aberration of the scanning transmission electron microscope (STEM) that started in Cambridge (UK) and continued in Kirkland (WA, USA), Yorktown Heights (NY, USA), and other places. We describe the project in the full context of other aberration correction research and related work, partly in response to the incomplete context presented in the paper “In quest of perfection in electron optics: A biographical sketch of Harald Rose on the occasion of his 80th birthday”, recently published in Ultramicroscopy. - Highlights: • We provide a brief history of the Cambridge project to correct the spherical aberration of the scanning transmission electron microscope (STEM). • We describe the project in the full context of other aberration correction work and related research. • We summarize our corrector development work that followed the Cambridge project, and which was the first to reach higher spatial resolution than any non-corrected electron microscope.

  18. Brief history of the Cambridge STEM aberration correction project and its progeny

    International Nuclear Information System (INIS)

    Brown, L. Michael; Batson, Philip E.; Dellby, Niklas; Krivanek, Ondrej L.

    2015-01-01

    We provide a brief history of the project to correct the spherical aberration of the scanning transmission electron microscope (STEM) that started in Cambridge (UK) and continued in Kirkland (WA, USA), Yorktown Heights (NY, USA), and other places. We describe the project in the full context of other aberration correction research and related work, partly in response to the incomplete context presented in the paper “In quest of perfection in electron optics: A biographical sketch of Harald Rose on the occasion of his 80th birthday”, recently published in Ultramicroscopy. - Highlights: • We provide a brief history of the Cambridge project to correct the spherical aberration of the scanning transmission electron microscope (STEM). • We describe the project in the full context of other aberration correction work and related research. • We summarize our corrector development work that followed the Cambridge project, and which was the first to reach higher spatial resolution than any non-corrected electron microscope

  19. Nutrition in medical education: reflections from an initiative at the University of Cambridge

    Directory of Open Access Journals (Sweden)

    Ball L

    2014-05-01

    Full Text Available Lauren Ball,1 Jennifer Crowley,2 Celia Laur,3 Minha Rajput-Ray,3 Stephen Gillam,4 Sumantra Ray3 1Nutrition and Dietetics, School of Allied Health Sciences, Centre for Health Practice Innovation, Griffith University, Queensland, Brisbane, Australia; 2Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; 3Need for Nutrition Education/Innovation Programme, Medical Research Council Human Nutrition Research, Cambridge, UK; 4Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK Abstract: Landmark reports have confirmed that it is within the core responsibilities of doctors to address nutrition in patient care. There are ongoing concerns that doctors receive insufficient nutrition education during medical training. This paper provides an overview of a medical nutrition education initiative at the University of Cambridge, School of Clinical Medicine, including 1 the approach to medical nutrition education, 2 evaluation of the medical nutrition education initiative, and 3 areas identified for future improvement. The initiative utilizes a vertical, spiral approach during the clinically focused years of the Cambridge undergraduate and graduate medical degrees. It is facilitated by the Nutrition Education Review Group, a group associated with the UK Need for Nutrition Education/Innovation Programme, and informed by the experiences of their previous nutrition education interventions. Three factors were identified as contributing to the success of the nutrition education initiative including the leadership and advocacy skills of the nutrition academic team, the variety of teaching modes, and the multidisciplinary approach to teaching. Opportunities for continuing improvement to the medical nutrition education initiative included a review of evaluation tools, inclusion of nutrition in assessment items, and further alignment of the Cambridge curriculum with the

  20. Accumulation and Circulation of the Knowledge Needed for Biotech Business Promotion by Engineers of R&D Section in an IT Enterprise: The Case of Hitachi Software Engineering Co., Ltd

    Directory of Open Access Journals (Sweden)

    Hirofumi Ota

    2012-01-01

    Full Text Available Much research has been carried out on the accumulation and effective use of knowledge as a company-specific form of intellectual property. However, insufficient attention has been given to research focusing on the effects of micro-level knowledge absorption and its effective use. In this paper, we try to demonstrate what should be done in order to promote new biotech business from the perspective of each engineer’s knowledge, through a micro-level investigation focusing on the life science business section of one IT enterprise. Based on the results of a questionnaire survey of engineers, interviews of several engineers, and patent data analysis, we discuss the progress of the biotech business in an IT enterprise from the aspect of accumulation and circulation of knowledge in a core technology field, the IT business, and a technology field of new entry, the biotech business. This paper reports that the positive growth cycle of biotech business promotion in an IT enterprise, using Hitachi Software Engineering Co., Ltd. as a case, attained by incorporating the latest biotech knowledge from junior engineers and utilizing IT knowledge from middle engineers leads to the recruiting of qualified students.Keywords: accumulation and circulation of the knowledge, biotech business, open innovation, patent data analysis, questionnaire survey

  1. Linguistic Turn and Gendering Language in the Cambridge Advanced Learner's Dictionary

    Science.gov (United States)

    Arimbi, Diah A.; Kwary, Deny A.

    2016-01-01

    Language constructs how humans perceive things. Since language is a human construction, it tends to be biased as it is mainly men's construction. Using gender perspectives, this paper attempts to discuss the imbalance in gender representations found in the examples given in an English learner's dictionary, that is, the "Cambridge Advanced…

  2. The Target of the Question: A Taxonomy of Textual Features for Cambridge University "O" Levels English

    Science.gov (United States)

    Benjamin, Shanti Isabelle

    2015-01-01

    This study investigates the typical textual features that are most frequently targeted in short-answer reading comprehension questions of the Cambridge University "O" Level English Paper 2. Test writers' awareness of how textual features impact on understanding of meanings in text decisions will determine to great extent their decisions…

  3. Probability Lessons at Hancock School, Lexington; Cambridge Conference on School Mathematics Feasibility Study No. 41.

    Science.gov (United States)

    McLane, Lyn

    These materials were written with the aim of reflecting the thinking of Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics. Presented are plans for teaching 23 probability lessons in the elementary grades at Hancock School, Lexington, Massachusetts. The discovery approach was utilized by the…

  4. Inequality Lessons at Adams School, Lexington; Cambridge Conference on School Mathematics Feasibility Study No. 42.

    Science.gov (United States)

    Fitzgerald, B.

    These materials were written with the aim of reflecting the thinking of The Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics. Presented are plans for teaching 15 inequality lessons for above average first grade students. The discovery approach is utilized by the teacher in order to involve…

  5. Informal Geometry for Young Children; Cambridge Conference on School Mathematics; Feasibility Study No. 34b.

    Science.gov (United States)

    Walter, Marion

    These materials were written with the aim of reflecting the thinking of The Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics. These materials are intended to provide children with a variety of informal activities in intuitive geometry in the elementary school. Opportunities are provided…

  6. Provisional Approaches to Goals for School Mathematics; Cambridge Conference on School Mathematics Feasibility Study No. 37.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    These materials were written with the aim of reflecting the thinking of Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics K-6. In view of the experiences of other curriculum groups and of the general discussions since 1963, the present report initiates the next step in evolving the "Goals".…

  7. [Geometry Through Symmetry, Cambridge Conference on School Mathematics Feasibility Study No. 32.

    Science.gov (United States)

    Friedman, Bernard

    These materials were written for the use of a class of eighth grade high ability students in a four week course sponsored by Educational Services Incorporated on the Stanford campus. They represent a practical response to the proposal by the Cambridge Conference of 1963 that geometry be taught by vector space methods. Instead of using vector…

  8. Final Report of Cambridge Conference on School Mathematics, January 1962 - August 1970.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    The Cambridge Conference on School Mathematics (CCSM) was an association of prominent mathematicians who had a concern for mathematics education at school level, from kindergarten through grade twelve. These mathematicians organized three main conferences in three areas of mathematics education, and have carried on activities related to the…

  9. Symmetry Motion Classes; Cambridge Conference on School Mathematics Feasibility Study No. 40.

    Science.gov (United States)

    McLane, Lyn

    These materials were written with the aim of reflecting the thinking of The Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for school mathematics. This document details the planning and response for each of ten lessons involving symmetry motions. The problems focused on (1) combining motions in a given order,…

  10. Factors Affecting Applications to Oxford and Cambridge--Repeat Survey. Executive Summary with Statistics

    Science.gov (United States)

    Ridley, Kate; White, Kerensa; Styles, Ben; Morrison, Jo

    2005-01-01

    This research follows up a study conducted in 1998 by the National Foundation for Educational Research (NFER) to investigate teachers' and students' views on the factors affecting students' choices of whether or not to apply to Oxford and Cambridge universities. It identifies what has changed since 1998 and areas in which the universities could…

  11. The Singapore-Cambridge General Certificate of Education Advanced-Level General Paper Examination

    Science.gov (United States)

    Hassan, Nurul Huda; Shih, Chih-Min

    2013-01-01

    This article describes and reviews the Singapore-Cambridge General Certificate of Education Advanced Level General Paper (GP) examination. As a written test that is administered to preuniversity students, the GP examination is internationally recognised and accepted by universities and employers as proof of English competence. In this article, the…

  12. Early detection of Alzheimer's disease using the Cambridge Cognitive Examination (CAMCOG)

    NARCIS (Netherlands)

    Schmand, B.; Walstra, G.; Lindeboom, J.; Teunisse, S.; Jonker, C.

    2000-01-01

    Dementia screening instruments, such as the Cambridge Cognitive Examination (CAMCOG), measure a variety of cognitive functions. However, memory impairment generally is the first sign of Alzheimer's disease (AD). It seems logical, therefore, to use only memory-related items for the early detection of

  13. What To Look for in ESL Admission Tests: Cambridge Certificate Exams, IELTS, and TOEFL.

    Science.gov (United States)

    Chalhoub-Deville, Micheline; Turner, Carolyn E.

    2000-01-01

    Familiarizes test users with issues to consider when employing assessments for screening and admission purposes. Examines the purpose, content, and scoring methods of three English-as-a-Second-Language admissions tests--the Cambridge certificate exams, International English Language Teaching System, and Test of English as a Foreign…

  14. Using the Concordancer in Vocabulary Development for the Cambridge Advanced English (CAE) Course.

    Science.gov (United States)

    Somogyi, Emma

    1996-01-01

    Discusses concordancing activities tailored for use with English-as-a-Second-Language (ESL) students in the Cambridge Advanced English course in Australia. The article focuses on students selecting appropriate vocabulary to complete gapped text. Findings indicate that these activities benefit ESL students by providing authentic examples of…

  15. Psychiatry in the Harvard Medical School-Cambridge Integrated Clerkship: An Innovative, Year-Long Program

    Science.gov (United States)

    Griswold, Todd; Bullock, Christopher; Gaufberg, Elizabeth; Albanese, Mark; Bonilla, Pedro; Dvorak, Ramona; Epelbaum, Claudia; Givon, Lior; Kueppenbender, Karsten; Joseph, Robert; Boyd, J. Wesley; Shtasel, Derri

    2012-01-01

    Objective: The authors present what is to their knowledge the first description of a model for longitudinal third-year medical student psychiatry education. Method: A longitudinal, integrated psychiatric curriculum was developed, implemented, and sustained within the Harvard Medical School-Cambridge Integrated Clerkship. Curriculum elements…

  16. An Improved Cambridge Filter Pad Extraction Methodology to Obtain More Accurate Water and “Tar” Values: In Situ Cambridge Filter Pad Extraction Methodology

    Directory of Open Access Journals (Sweden)

    Ghosh David

    2014-07-01

    Full Text Available Previous investigations by others and internal investigations at Philip Morris International (PMI have shown that the standard trapping and extraction procedure used for conventional cigarettes, defined in the International Standard ISO 4387 (Cigarettes -- Determination of total and nicotine-free dry particulate matter using a routine analytical smoking machine, is not suitable for high-water content aerosols. Errors occur because of water losses during the opening of the Cambridge filter pad holder to remove the filter pad as well as during the manual handling of the filter pad, and because the commercially available filter pad holder, which is constructed out of plastic, may adsorb water. This results in inaccurate values for the water content, and erroneous and overestimated values for Nicotine Free Dry Particulate Matter (NFDPM. A modified 44 mm Cambridge filter pad holder and extraction equipment which supports in situ extraction methodology has been developed and tested. The principle of the in situ extraction methodology is to avoid any of the above mentioned water losses by extracting the loaded filter pad while kept in the Cambridge filter pad holder which is hermetically sealed by two caps. This is achieved by flushing the extraction solvent numerous times through the hermetically sealed Cambridge filter pad holder by means of an in situ extractor. The in situ methodology showed a significantly more complete water recovery, resulting in more accurate NFDPM values for high-water content aerosols compared to the standard ISO methodology. The work presented in this publication demonstrates that the in situ extraction methodology applies to a wider range of smoking products and smoking regimens, whereas the standard ISO methodology only applies to a limited range of smoking products and smoking regimens, e.g., conventional cigarettes smoked under ISO smoking regimen. In cases where a comparison of yields between the PMI HTP and

  17. Mime, Music and Drama on the Eighteenth-Century Stage. The Ballet d'Action. Edward Nye, Cambridge-New York, Cambridge University Press, 2011

    Directory of Open Access Journals (Sweden)

    Stefania Onesti

    2012-11-01

    Full Text Available Mime, Music and Drama on the Eighteenth-Century Stage by Edward Nye (Cambridge University Press, 2011 has the merit of inspiring a strong reflection on ballet d'action, connected with cultural, literaturary and philosophic environment of Eighteenth century. The author, with brilliant insight and careful historical research, explores the most debated issues of the new genre, providing an unusual interpretation. The review traces the focal points and the structure of the book, developing further consideration of some of the most challenging aspects offered by the text.

  18. The Cambridge Car Memory Test: a task matched in format to the Cambridge Face Memory Test, with norms, reliability, sex differences, dissociations from face memory, and expertise effects.

    Science.gov (United States)

    Dennett, Hugh W; McKone, Elinor; Tavashmi, Raka; Hall, Ashleigh; Pidcock, Madeleine; Edwards, Mark; Duchaine, Bradley

    2012-06-01

    Many research questions require a within-class object recognition task matched for general cognitive requirements with a face recognition task. If the object task also has high internal reliability, it can improve accuracy and power in group analyses (e.g., mean inversion effects for faces vs. objects), individual-difference studies (e.g., correlations between certain perceptual abilities and face/object recognition), and case studies in neuropsychology (e.g., whether a prosopagnosic shows a face-specific or object-general deficit). Here, we present such a task. Our Cambridge Car Memory Test (CCMT) was matched in format to the established Cambridge Face Memory Test, requiring recognition of exemplars across view and lighting change. We tested 153 young adults (93 female). Results showed high reliability (Cronbach's alpha = .84) and a range of scores suitable both for normal-range individual-difference studies and, potentially, for diagnosis of impairment. The mean for males was much higher than the mean for females. We demonstrate independence between face memory and car memory (dissociation based on sex, plus a modest correlation between the two), including where participants have high relative expertise with cars. We also show that expertise with real car makes and models of the era used in the test significantly predicts CCMT performance. Surprisingly, however, regression analyses imply that there is an effect of sex per se on the CCMT that is not attributable to a stereotypical male advantage in car expertise.

  19. Psychometric properties of the Calgary Cambridge guides to assess communication skills of undergraduate medical students.

    OpenAIRE

    Simmenroth-Nayda, Anne; Heinemann, Stephanie; Nolte, Catharina; Fischer, Thomas; Himmel, Wolfgang

    2014-01-01

    OBJECTIVE: The aim of this study was to analyse the psychometric properties of the short version of the Calgary Cambridge Guides and to decide whether it can be recommended for use in the assessment of communications skills in young undergraduate medical students. METHODS: Using a translated version of the Guide, 30 members from the Department of General Practice rated 5 videotaped encounters between students and simulated patients twice. Item analysis should detect possible floor and/or...

  20. PET/MRI in the infarcted mouse heart with the Cambridge split magnet

    International Nuclear Information System (INIS)

    Buonincontri, Guido; Sawiak, Stephen J.; Methner, Carmen; Krieg, Thomas; Hawkes, Robert C.; Adrian Carpenter, T.

    2013-01-01

    Chronic heart failure, as a result of acute myocardial infarction, is a leading cause of death worldwide. Combining diagnostic imaging modalities may aid the direct assessment of experimental treatments targeting heart failure in vivo. Here we present preliminary data using the Cambridge combined PET/MRI imaging system in a mouse model of acute myocardial infarction. The split-magnet design can deliver uncompromised MRI and PET performance, for better assessment of disease and treatment in a preclinical environment

  1. Inequality and growth in neo-Kaleckian and Cambridge growth theory

    OpenAIRE

    Palley, Thomas I.

    2016-01-01

    This paper examines the relationship between inequality and growth in the neo-Kaleckian and Cambridge growth models. The paper explores the channels whereby functional and personal income distribution impact growth. The growth - inequality relationship can be negative or positive, depending on the economy's characteristics. Contrary to widespread claims, inequality per se does not impact growth through macroeconomic channels. Instead, both growth and inequality are impacted by changes in the ...

  2. Cambridge Homes Increases Energy Efficiency in a Mix of Housing Types

    International Nuclear Information System (INIS)

    Poole, L.; Anderson, R.

    2001-01-01

    New houses designed by Cambridge Homes in Crest Hill, Illinois, with technical support from the U.S. Department of Energy's Building America Program, save their homeowners money by applying the principles of ''whole-building'' design to the entire home product line. Regardless of the model chosen, home buyers can enjoy consistently high levels of comfort and performance with the added benefit of reduced operating costs

  3. Hamming's "open doors" and group creativity as keys to scientific excellence: the example of Cambridge.

    Science.gov (United States)

    Erren, Thomas C

    2008-01-01

    Dr. Charlton used diverse approaches to identify research institutions which provided home to outstanding scientists and work. One intriguing example of long-lasting scientific excellence is Cambridge with 19 Nobel laureates who worked at the University or at the MRC Molecular Biology Unit when they received the prize between 1947 and 2006. With specific reference to Cambridge, I would like to complement the primarily quantitative assessment and offer considerations as to why and how research achievements may have clustered in space and time. Indeed, observations voiced by the mathematician Richard Hamming as to how great research can be pursued offer explanations for the series of great science in the UK. In my view, the most important determinant of the clustering may be illustrated by Hamming's fitting picture of "open doors": working in environments with the doors open allows constant interactions with peers with various disciplinary backgrounds, and thus fast avoidance of detours or dead ends in science and, ultimately, a focus on and the solution of problems of paramount, rather than of tangential, importance. Narrative insights into a strong argumentative tradition at Cambridge provided by Drs. Watson and Magueijo between 1968 and 2003 are in line with Hamming's suggestion and the value of group creativity. In the internet age with abundant interactions beyond home institutions we should not be surprised if clusters of great science were no longer confined to the usual suspect institutions which were awarded disproportionally with Nobel prizes in the past.

  4. Analysis of pharmacist-patient communication using the Calgary-Cambridge guide.

    Science.gov (United States)

    Greenhill, Nicola; Anderson, Claire; Avery, Anthony; Pilnick, Alison

    2011-06-01

    This study explored communication between pharmacists and patients through application of the Calgary-Cambridge guide [1] to appointment-based pharmacist-patient consultations and considers use of the guide in pharmacy education. Eighteen patients attending appointment-based consultations with five pharmacists were recruited to this qualitative study. Consultations were audio-recorded and observed. Transcripts were coded according to the use of skills within the guide and analysed thematically. The results showed good use of many skills by pharmacists, particularly signposting and closing the session. Some skills were poorly represented such as listening effectively, eliciting the patient's perspective, effective use of computers and creating patient-centred consultations. A key theme of social conversation was present in the data but this skill was not defined in the guide. The Calgary-Cambridge guide was developed for use in medical consultations but its application to pharmacist-patient consultations showed that the guide could be successfully used in pharmacy with some minor alterations. Pharmacists may need more training to improve the use of specific communication skills including how to conduct a patient-centred consultation. The Calgary-Cambridge guide is well aligned with many aspects of pharmacist-patient consultations and could help pharmacists to improve their consultation skills. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  5. What affects the innovation performance of small and medium-sized enterprises (SMEs) in the biotechnology industry? An empirical study on Korean biotech SMEs.

    Science.gov (United States)

    Kang, Kyung-Nam; Lee, Yoon-Sik

    2008-10-01

    Research-intensive small and medium-sized enterprises (SMEs) play a crucial role in the advancement of the biotechnology industry. This paper explored the impacts of internal and contextual variables on innovative activity in Korea and compared the results of this analysis with previous studies of other countries. Our analysis of 149 Korean biotech SMEs showed that the ratio of R&D expenditure to sales, the ratio of R&D employees to total employees, CEO characteristics, governmental support and international networking are positively correlated with a firm's innovation performance. The results may help decision makers to better foster SMEs in the Korean biotechnology industry.

  6. Adaptation of the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR into French-Canadian and English-Canadian

    Directory of Open Access Journals (Sweden)

    Donna Coffin

    2008-01-01

    Full Text Available BACKGROUND: The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR is the first disease-specific instrument for assessing patient-reported symptoms, functioning and quality of life (QoL in pulmonary arterial hypertension (PAH.

  7. Public administration and R&D localisation by pharmaceutical and biotech companies: a theoretical framework and the Italian case-study.

    Science.gov (United States)

    Jommi, Claudio; Paruzzolo, Silvia

    2007-04-01

    This article has two objectives. It firstly provides a general framework for variables that influence R&D (Research and Development) localisation by pharmaceutical and biotech companies. The analysis of R&D localization includes both in-house R&D and contracted R&D. Following a systematic literature search, these variables were classified into four distinct categories: regulatory environment, institutional framework, national systems of innovation and local development and specialisation. The authors highlight that some of these factors directly depend on the action of public administrations (e.g., patent protection, price regulation, public investments in research, and incentives to private companies); others are indirectly influenced by public policies (e.g., GDP growth rate, infrastructures). This theoretical framework was used to analyse the Italian case-study. Pros and cons of the Italian context were investigated from the point of view of multinational pharmaceutical companies and the Italian Association of Biotech Companies. Interviews were chosen as the most appropriate data gathering technique given the exploratory nature of the study of the Italian context. The paper is divided into five parts. A brief introduction provides figures showing that Europe has been loosing positions compared with other Continents and the same has occurred in Italy compared with other EU countries. The second one illustrates the methodology. The third one is focused on variables affecting R&D localisation. In the fourth section the Italian case-study is discussed. Theoretical and empirical findings are summarised and discussed in the conclusions.

  8. Cambridge Rocketry Simulator – A Stochastic Six-Degrees-of-Freedom Rocket Flight Simulator

    OpenAIRE

    Eerland, Willem J.; Box, Simon; Sóbester, András

    2017-01-01

    The Cambridge Rocketry Simulator can be used to simulate the flight of unguided rockets for both design and operational applications. The software consists of three parts: The first part is a GUI that enables the user to design a rocket. The second part is a verified and peer-reviewed physics model that simulates the rocket flight. This includes a Monte Carlo wrapper to model the uncertainty in the rocket’s dynamics and the atmospheric conditions. The third part generates visualizations of th...

  9. Using the Cambridge structure database of organic and organometalic compounds in structure biology

    Czech Academy of Sciences Publication Activity Database

    Hašek, Jindřich

    2010-01-01

    Roč. 17, 1a (2010), b24-b26 ISSN 1211-5894. [Discussions in Structural Molecular Biology /8./. Nové Hrady, 18.03.2010-20.03.2010] R&D Projects: GA AV ČR IAA500500701; GA ČR GA305/07/1073 Institutional research plan: CEZ:AV0Z40500505 Keywords : organic chemistry * Cambridge Structure Data base * molecular structure Subject RIV: CD - Macromolecular Chemistry http://xray.cz/ms/bul2010-1a/friday2.pdf

  10. Cambridge observations at 38-115 MHz and their implications for space astronomy

    International Nuclear Information System (INIS)

    Saunders, R.

    1987-01-01

    The design and performance of the Cambridge LF telescopes are reviewed. Consideration is given to the 151-MHz 6C telescope, the 38-MHz and 151-MHz LF synthesis telescopes, 81.5-MHz interplanetary scintillation observations with the 3.6-hectare array, long-baseline interferometry at 81.5 MHz, and the use of the Jodrell Bank MERLIN for 151-MHz closure-phase observations of bright sources. The strict limitation on the field mappable at a given resolution in ground-based observations at these frequencies is pointed out, and some outstanding astronomical problems requiring 0.3-30-MHz space observations are listed. 7 references

  11. De Cambridge a Brighton: Poesia Concreta na Grã-Bretanha, uma entrevista com Stephen Bann

    OpenAIRE

    Montero - University of the Arts, Gustavo Grandal; Albertoni (trad.) - University of the Arts London, Fernanda

    2016-01-01

    Extensa entrevista com o historiador da arte, curador e poeta concreto Stephen Bann, realizada por Gustavo Grandal Montero, concentrando-se em seu trabalho curatorial, crítico e artístico da década de 1960, em que esteve intimamente envolvido com o desenvolvimento da poesia concreta no Reino Unido. Bann associou-se precocemente com Ian Hamilton Finlay, co-organizou a Primeira exposição internacional de poesia concreta e cinética (Cambridge, 1964) e foi o curador da Exposição de Poesia Concret...

  12. Plant Biotech Lab Manual.

    Science.gov (United States)

    Tant, Carl

    This book provides laboratory experiments to enhance any food science/botany curriculum. Chapter 1, "Introduction," presents a survey of the techniques used in plant biotechnology laboratory procedures. Chapter 2, "Micronutrition," discusses media and nutritional requirements for tissue culture studies. Chapter 3, "Sterile Seeds," focuses on the…

  13. Using Item Analysis to Assess Objectively the Quality of the Calgary-Cambridge OSCE Checklist

    Directory of Open Access Journals (Sweden)

    Tyrone Donnon

    2011-06-01

    Full Text Available Background:  The purpose of this study was to investigate the use of item analysis to assess objectively the quality of items on the Calgary-Cambridge Communications OSCE checklist. Methods:  A total of 150 first year medical students were provided with extensive teaching on the use of the Calgary-Cambridge Guidelines for interviewing patients and participated in a final year end 20 minute communication OSCE station.  Grouped into either the upper half (50% or lower half (50% communication skills performance groups, discrimination, difficulty and point biserial values were calculated for each checklist item. Results:  The mean score on the 33 item communication checklist was 24.09 (SD = 4.46 and the internal reliability coefficient was ? = 0.77. Although most of the items were found to have moderate (k = 12, 36% or excellent (k = 10, 30% discrimination values, there were 6 (18% identified as ‘fair’ and 3 (9% as ‘poor’. A post-examination review focused on item analysis findings resulted in an increase in checklist reliability (? = 0.80. Conclusions:  Item analysis has been used with MCQ exams extensively. In this study, it was also found to be an objective and practical approach to use in evaluating the quality of a standardized OSCE checklist.

  14. The present state of research and exploitation of biotech (GM) crops in horticulture: results of research on plum cv. 'HoneySweet' resistant to plum pox virus (Sharka) and the deregulation of this cultivar in the CR & Europe

    Science.gov (United States)

    Gentically modified (GM) crops were grown world-wide on 160 million ha in 2011. Only 114.57 ha of GM crops were grown in Europe, of that, 114.90 ha were Bt maize and 17 ha were potato for industrial starch production. Commercialization of Biotech crops started in 1995. Currently, developing count...

  15. Two new species of the genus Paramitraceras Pickard-Cambridge, 1905 (Opiliones: Laniatores: Stygnopsidae) from Chiapas, Mexico.

    Science.gov (United States)

    Cruz-López, Jesús A; Francke, Oscar F

    2013-01-01

    Parainitraceras pickardcanibridgei sp. nov. and Paramitraceras tzotzil sp. nov. from Chiapas, Mexico are described based on specimens previously determined as Paramitraceras granulatum Pickard-Cambridge, 1905 by Goodnight and Goodnight. The male genitalia of the new species and P. granulatum are illustrated with scanning electronic micrographs (SEMs) or drawings derived from them. The importance of the ocular tubercle, cheliceral dentition and sexual dimorphism, pedipalpal armature and male genitalia as taxonomic characters within the genus is discussed as well as differences and similarities between Paramitraceras Pickard-Cambridge, 1905 and its most similar genus, Sbordonia Šilhavý, 1977.

  16. Cambridge Rocketry Simulator – A Stochastic Six-Degrees-of-Freedom Rocket Flight Simulator

    Directory of Open Access Journals (Sweden)

    Willem J. Eerland

    2017-02-01

    Full Text Available The Cambridge Rocketry Simulator can be used to simulate the flight of unguided rockets for both design and operational applications. The software consists of three parts: The first part is a GUI that enables the user to design a rocket. The second part is a verified and peer-reviewed physics model that simulates the rocket flight. This includes a Monte Carlo wrapper to model the uncertainty in the rocket’s dynamics and the atmospheric conditions. The third part generates visualizations of the resulting trajectories, including nominal performance and uncertainty analysis, e.g. a splash-down region with confidence bounds. The project is available on SourceForge, and is written in Java (GUI, C++ (simulation core, and Python (visualization. While all parts can be executed from the GUI, the three components share information via XML, accommodating modifications, and re-use of individual components.

  17. Fiftieth Anniversary of the Cambridge Structural Database and Thirty Years of Its Use in Croatia

    Directory of Open Access Journals (Sweden)

    Kojić-Prodić B.

    2015-07-01

    Full Text Available This article is dedicated to the memory of Dr. F. H. Allen and the 50th anniversary of the Cambridge Crystallographic Data Centre (CCDC; the world-renowned centre for deposition and control of crystallographic data including atomic coordinates that define the three-dimensional structures of organic molecules and metal complexes containing organic ligands. The mission exposed at the web site (http://www.ccdc.cam.ac.uk is clearly stated: “The Cambridge Crystallographic Data Centre (CCDC is dedicated to the advancement of chemistry and crystallography for the public benefit through providing high quality information, software and services.” The Cambridge Structural Database (CSD, one among the first established electronic databases, nowadays is one of the most significant crystallographic databases in the world. In the International Year of Crystallography 2014, the CSD announced in December over 750,000 deposited structures. The use of the extensive and rapidly growing database needs support of sophisticated and efficient software for checking, searching, analysing, and visualising structural data. The seminal role of the CSD in researches related to crystallography, chemistry, materials science, solid state physics and chemistry, (biotechnology, life sciences, and pharmacology is widely known. The important issues of the CCDC are the accuracy of deposited data and development of software for checking the data. Therefore, the Crystallographic Information File (CIF is introduced as the standard text file format for representing crystallographic information. Among the most important software for users is ConQuest, which enables searching all the CSD information fields, and the web implementation WebCSD software. Mercury is available for visualisation of crystal structures and crystal morphology including intra- and intermolecular interactions with graph-set notations of hydrogen bonds, and analysis of geometrical parameters. The CCDC gives even

  18. Reginald Crundall Punnett: first Arthur Balfour Professor of Genetics, Cambridge, 1912.

    Science.gov (United States)

    Edwards, A W F

    2012-09-01

    R. C. Punnett, the codiscoverer of linkage with W. Bateson in 1904, had the good fortune to be invited to be the first Arthur Balfour Professor of Genetics at Cambridge University, United Kingdom, in 1912 when Bateson, for whom it had been intended, declined to leave his new appointment as first Director of the John Innes Horticultural Institute. We here celebrate the centenary of the first professorship dedicated to genetics, outlining Punnett's career and his scientific contributions, with special reference to the discovery of "partial coupling" in the sweet pea (later "linkage") and to the diagram known as Punnett's square. His seeming reluctance as coauthor with Bateson to promote the reduplication hypothesis to explain the statistical evidence for linkage is stressed, as is his relationship with his successor as Arthur Balfour Professor, R. A. Fisher. The background to the establishment of the Professorship is also described.

  19. Psychiatry in the Harvard Medical School-Cambridge Integrated Clerkship: an innovative, year-long program.

    Science.gov (United States)

    Griswold, Todd; Bullock, Christopher; Gaufberg, Elizabeth; Albanese, Mark; Bonilla, Pedro; Dvorak, Ramona; Epelbaum, Claudia; Givon, Lior; Kueppenbender, Karsten; Joseph, Robert; Boyd, J Wesley; Shtasel, Derri

    2012-09-01

    The authors present what is to their knowledge the first description of a model for longitudinal third-year medical student psychiatry education. A longitudinal, integrated psychiatric curriculum was developed, implemented, and sustained within the Harvard Medical School-Cambridge Integrated Clerkship. Curriculum elements include longitudinal mentoring by attending physicians in an outpatient psychiatry clinic, exposure to the major psychotherapies, psychopharmacology training, acute psychiatry "immersion" experiences, and a variety of clinical and didactic teaching sessions. The longitudinal psychiatry curriculum has been sustained for 8 years to-date, providing effective learning as demonstrated by OSCE scores, NBME shelf exam scores, written work, and observed clinical work. The percentage of students in this clerkship choosing psychiatry as a residency specialty is significantly greater than those in traditional clerkships at Harvard Medical School and greater than the U.S. average. Longitudinal integrated clerkship experiences are effective and sustainable; they offer particular strengths and opportunities for psychiatry education, and may influence student choice of specialty.

  20. Floodplain management: Land acquisition versus preservation of historic buildings in Cambridge, Ontario, Canada

    Science.gov (United States)

    Bennett, Wendy J.; Mitchell, Bruce

    1983-07-01

    Non-structural adjustments in floodplain management are often avoided because they are seen to infringe on personal rights, adversely affect property values and restrict local tax bases. Land acquisition programs in urban areas encounter a further problem when they lead to demolition of buildings and other structures considered to have historical or architectural value. An experience in Cambridge, Ontario demonstrates that the potential conflict between flood damage reduction and historical preservation objectives can be exacerbated as a result of uncoordinated planning efforts, inflexibility in interpreting mandates, unclear roles for participating agencies, and lack of cooperation Many of these dilemmas can be resolved through consultation and discussion early in the planning process as well as through a willingness to be flexible and to search for a compromise

  1. Cheminformatics Research at the Unilever Centre for Molecular Science Informatics Cambridge.

    Science.gov (United States)

    Fuchs, Julian E; Bender, Andreas; Glen, Robert C

    2015-09-01

    The Centre for Molecular Informatics, formerly Unilever Centre for Molecular Science Informatics (UCMSI), at the University of Cambridge is a world-leading driving force in the field of cheminformatics. Since its opening in 2000 more than 300 scientific articles have fundamentally changed the field of molecular informatics. The Centre has been a key player in promoting open chemical data and semantic access. Though mainly focussing on basic research, close collaborations with industrial partners ensured real world feedback and access to high quality molecular data. A variety of tools and standard protocols have been developed and are ubiquitous in the daily practice of cheminformatics. Here, we present a retrospective of cheminformatics research performed at the UCMSI, thereby highlighting historical and recent trends in the field as well as indicating future directions.

  2. Oxford and Cambridge Boat Race: Performance, Pacing and Tactics Between 1890 and 2014.

    Science.gov (United States)

    Edwards, Andrew M; Guy, Joshua H; Hettinga, Florentina J

    2016-10-01

    Currently no studies have examined the historical performances of Oxford and Cambridge Boat Race crews in the context of performance, pacing and tactics which is surprising as the event has routinely taken place annually for over 150 years on the same course. The purpose of this study was twofold, to firstly examine the historical development of performances and physical characteristics of crews over 124 years of the Oxford and Cambridge Boat Race between 1890 and 2014 and secondly to investigate the pacing and tactics employed by crews over that period. Linear regression modelling was applied to investigate the development of performance and body size for crews of eight male individuals over time from Boat Race archive data. Performance change over time was further assessed in 10-year clusters while four intra-race checkpoints were used to examine pacing and tactics. Significant correlations were observed between performance and time (1890-2014) for both Oxford (r = -0.67; p tactical advantage from commencing on either the Surrey or Middlesex station beyond chance alone; however, all crews (n = 228) adopted a fast-start strategy, with 81 % of victories achieved by the crew leading the race at the first intra-race checkpoint (24 % of total distance). Crews leading the race at the final checkpoint (83 % of total distance; 1143 m) achieved victory on 94 % of occasions. Performances and physical characteristics of the crews have changed markedly since 1890, with faster heavier crews now common. Tactically, gaining the early lead position with a fast-start strategy seems particularly meaningful to success in the Boat Race throughout the years, and has been of greater importance to race outcome than factors such as the starting station.

  3. Bericht uber den 2. Internationalen Kongress fur Angewandte Linguistik. Cambridge 8.-12. IX. 1969. [Report on the Second International Congress for Applied Linguistics, Cambridge, Dec. 8-12, 1969.

    Science.gov (United States)

    Mohr, Peter

    This paper is a summary report on the Second International Congress of Applied Linguistics held in Cambridge, England in September 1969. Because of the large number of papers delivered, only a selection of the papers delivered in any one section of the Congress are considered, and the author attempts to identify current interests and trends in…

  4. First record of Centromerus arcanus (O. P.-Cambridge, 1873) from Greenland (Araneae, Linyphiidae)

    DEFF Research Database (Denmark)

    Lissner, Jørgen; Gravesen, Eigil Vestergaard

    2017-01-01

    The linyphiid spider Centromerus arcanus (O. P.-Cambridge, 1873) is reported new to Greenland. A single female was pitfall trapped in South-West Greenland at Kobbefjord in the summer of 2016 constituting the first record of this species in the Nearctic ecozone. The habitat in which the Greenland...

  5. A FIRST STEP TOWARDS THE IMPLEMENTATION OF THE CAMBRIDGE MATHEMATICS CURRICULUM IN A K-12 UNGRADED SCHOOL.

    Science.gov (United States)

    FOSTER, GARRETT R.

    A SERIES OF THREE CONFERENCES WAS HELD TO EXPLORE THE FEASIBILITY OF IMPLEMENTING A LONG-RANGE CURRICULUM DEVELOPMENT PROJECT FOR AN UNGRADED, K-12 SCHOOL, BASED ON RECOMMENDATIONS OF THE CAMBRIDGE CONFERENCE ON SCHOOL MATHEMATICS. OVER 50 MATHEMATICIANS, MATHEMATICS EDUCATORS, AND PERSONS INVOLVED IN THEORETICAL AND APPLIED PSYCHOLOGICAL…

  6. Inequalities and Real Numbers as a Basis for School Mathematics, Cambridge Conference on School Mathematics Feasibility Study No. 38.

    Science.gov (United States)

    Lomon, Earle

    These materials were developed as a practical response to some of the recommendations of the 1963 Cambridge Conference on School Mathematics (CCSM). Experimental sessions are described in detail in this report. In the Estabrook Elementary School, Lexington, Massachusetts, first grade children (1964-65 Academic Year) concentrated on material…

  7. An Experimental Text in Transformational Geometry, Student Text; Cambridge Conference on School Mathematics Feasibility Study No. 43a.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    This is part of a student text which was written with the aim of reflecting the thinking of The Cambridge Conference on School Mathematics (CCSM) regarding the goals and objectives for mathematics. The instructional materials were developed for teaching geometry in the secondary schools. This document is chapter six and titled Motions and…

  8. Goals for Mathematical Education of Elementary School Teachers: A Report of the Cambridge Conference on Teacher Training.

    Science.gov (United States)

    Education Development Center, Inc., Newton, MA.

    This report is intended to provide attention to issues that the Cambridge Conference feels are related to the mathematical training of elementary school teachers. The document is divided into three parts. Part I, titled "The Problems and Proposals Towards the Solution," contains the following chapters: (1) Introduction to the Report; (2)…

  9. Tartu Ülikooli teadur kaitses Cambridgeì Ülikoolis doktorikraadi / Krõõt Nõges

    Index Scriptorium Estoniae

    Nõges, Krõõt

    2006-01-01

    Tartu Ülikooli filosoofia osakonna teadur ja eetikakeskuse stipendiaat Eva Piirimäe kaitses Cambridgeì Ülikoolis doktorikraadi ideede ajaloo erialal doktoritööga "Thomas Abbt (1738-1766) and the Philosophical Genesis of German Nationalism"

  10. BOOK REVIEW - The Experience of Face Veil Wearers in Europe and the Law (Cambridge University Press United Kingdom 2014. ISBN 978-1-107-05830-9.

    Directory of Open Access Journals (Sweden)

    Jacques L Matthee

    2017-03-01

    Full Text Available This contribution published by Cambridge University Press provides a short overview of the book by Eva Brems "The Experience of Face Veil Wearers in Europe and the Law" published by Cambridge University Press, United Kingdom, in 2014. See ISBN 978-1-107-05830-9.

  11. Diagnosing prosopagnosia in East Asian individuals: Norms for the Cambridge Face Memory Test-Chinese.

    Science.gov (United States)

    McKone, Elinor; Wan, Lulu; Robbins, Rachel; Crookes, Kate; Liu, Jia

    2017-07-01

    The Cambridge Face Memory Test (CFMT) is widely accepted as providing a valid and reliable tool in diagnosing prosopagnosia (inability to recognize people's faces). Previously, large-sample norms have been available only for Caucasian-face versions, suitable for diagnosis in Caucasian observers. These are invalid for observers of different races due to potentially severe other-race effects. Here, we provide large-sample norms (N = 306) for East Asian observers on an Asian-face version (CFMT-Chinese). We also demonstrate methodological suitability of the CFMT-Chinese for prosopagnosia diagnosis (high internal reliability, approximately normal distribution, norm-score range sufficiently far above chance). Additional findings were a female advantage on mean performance, plus a difference between participants living in the East (China) or the West (international students, second-generation children of immigrants), which we suggest might reflect personality differences associated with willingness to emigrate. Finally, we demonstrate suitability of the CFMT-Chinese for individual differences studies that use correlations within the normal range.

  12. Hydrocephalus shunt technology: 20 years of experience from the Cambridge Shunt Evaluation Laboratory.

    Science.gov (United States)

    Chari, Aswin; Czosnyka, Marek; Richards, Hugh K; Pickard, John D; Czosnyka, Zofia H

    2014-03-01

    The Cambridge Shunt Evaluation Laboratory was established 20 years ago. This paper summarizes the findings of that laboratory for the clinician. Twenty-six models of valves have been tested long-term in the shunt laboratory according to the expanded International Organization for Standardization 7197 standard protocol. The majority of the valves had a nonphysiologically low hydrodynamic resistance (from 1.5 to 3 mm Hg/[ml/min]), which may result in overdrainage related to posture and during nocturnal cerebral vasogenic waves. A long distal catheter increases the resistance of these valves by 100%-200%. Drainage through valves without a siphon-preventing mechanism is very sensitive to body posture, which may result in grossly negative intracranial pressure. Siphon-preventing accessories offer a reasonable resistance to negative outlet pressure; however, accessories with membrane devices may be blocked by raised subcutaneous pressure. In adjustable valves, the settings may be changed by external magnetic fields of intensity above 40 mT (exceptions: ProGAV, Polaris, and Certas). Most of the magnetically adjustable valves produce large distortions on MRI studies. The behavior of a valve revealed during testing is of relevance to the surgeon and may not be adequately described in the manufacturer's product information. The results of shunt testing are helpful in many circumstances, such as the initial choice of shunt and the evaluation of the shunt when its dysfunction is suspected.

  13. Psychometric properties of the Calgary Cambridge guides to assess communication skills of undergraduate medical students.

    Science.gov (United States)

    Simmenroth-Nayda, Anne; Heinemann, Stephanie; Nolte, Catharina; Fischer, Thomas; Himmel, Wolfgang

    2014-12-06

    The aim of this study was to analyse the psychometric properties of the short version of the Calgary Cambridge Guides and to decide whether it can be recommended for use in the assessment of communications skills in young undergraduate medical students. Using a translated version of the Guide, 30 members from the Department of General Practice rated 5 videotaped encounters between students and simulated patients twice. Item analysis should detect possible floor and/or ceiling effects. The construct validity was investigated using exploratory factor analysis. Intra-rater reliability was measured in an interval of 3 months, inter-rater reliability was assessed by the intraclass correlation coefficient. The score distribution of the items showed no ceiling or floor effects. Four of the five factors extracted from the factor analysis represented important constructs of doctor-patient communication The ratings for the first and second round of assessing the videos correlated at 0.75 (p<0.0001). Intraclass correlation coefficients for each item ranged were moderate and ranged from 0.05 to 0.57. Reasonable score distributions of most items without ceiling or floor effects as well as a good test-retest reliability and construct validity recommend the C-CG as an instrument for assessing communication skills in undergraduate medical students. Some deficiencies in inter-rater reliability are a clear indication that raters need a thorough instruction before using the C-CG.

  14. Minimal exposure technique in the Cambridge University 600kV high resolution electron microscope

    International Nuclear Information System (INIS)

    Fryer, J.R.; Cleaver, J.R.A.; Smith, D.J.

    1980-01-01

    Radiation damage due to the incident electron beam imposes a fundamental limitation on the information obtainable by electron microscopy about organic materials; it is desirable therefore that exposure of the specimen to the electron beam should be restricted to the actual period during which the image is being recorded. A description is given of methods employed in the observation of the organic aromatic hydrocarbons quaterrylene, ovalene and coronene with the Cambridge University 600kV high resolution electron microscope (HREM). In particular, the condenser-objective mode of operation of this microscope lends itself to the use of an area-defining aperture below the second condenser lens conjugate with the specimen. Furthermore, operation at the higher accelerating voltage of this instrument could be anticipated to reduce the rate of damage, depending on the dominant beam-specimen interaction, whilst the increased width of the first broad band of the contrast transfer function of this microscope at the optimum defocus may overcome the reported resolution limitation of current 100kV microscopes for the observation of related materials. (author)

  15. Characteristic conformation of Mosher's amide elucidated using the cambridge structural database.

    Science.gov (United States)

    Ichikawa, Akio; Ono, Hiroshi; Mikata, Yuji

    2015-07-16

    Conformations of the crystalline 3,3,3-trifluoro-2-methoxy-2-phenylpropanamide derivatives (MTPA amides) deposited in the Cambridge Structural Database (CSD) were examined statistically as Racid-enantiomers. The majority of dihedral angles (48/58, ca. 83%) of the amide carbonyl groups and the trifluoromethyl groups ranged from -30° to 0° with an average angle θ1 of -13°. The other conformational properties were also clarified: (1) one of the fluorine atoms was antiperiplanar (ap) to the amide carbonyl group, forming a staggered conformation; (2) the MTPA amides prepared from primary amines showed a Z form in amide moieties; (3) in the case of the MTPA amide prepared from a primary amine possessing secondary alkyl groups (i.e., Mosher-type MTPA amide), the dihedral angles between the methine groups and the carbonyl groups were syn and indicative of a moderate conformational flexibility; (4) the phenyl plane was inclined from the O-Cchiral bond of the methoxy moiety with an average dihedral angle θ2 of +21°; (5) the methyl group of the methoxy moiety was ap to the ipso-carbon atom of the phenyl group.

  16. Item Response Theory Analyses of the Cambridge Face Memory Test (CFMT)

    Science.gov (United States)

    Cho, Sun-Joo; Wilmer, Jeremy; Herzmann, Grit; McGugin, Rankin; Fiset, Daniel; Van Gulick, Ana E.; Ryan, Katie; Gauthier, Isabel

    2014-01-01

    We evaluated the psychometric properties of the Cambridge face memory test (CFMT; Duchaine & Nakayama, 2006). First, we assessed the dimensionality of the test with a bi-factor exploratory factor analysis (EFA). This EFA analysis revealed a general factor and three specific factors clustered by targets of CFMT. However, the three specific factors appeared to be minor factors that can be ignored. Second, we fit a unidimensional item response model. This item response model showed that the CFMT items could discriminate individuals at different ability levels and covered a wide range of the ability continuum. We found the CFMT to be particularly precise for a wide range of ability levels. Third, we implemented item response theory (IRT) differential item functioning (DIF) analyses for each gender group and two age groups (Age ≤ 20 versus Age > 21). This DIF analysis suggested little evidence of consequential differential functioning on the CFMT for these groups, supporting the use of the test to compare older to younger, or male to female, individuals. Fourth, we tested for a gender difference on the latent facial recognition ability with an explanatory item response model. We found a significant but small gender difference on the latent ability for face recognition, which was higher for women than men by 0.184, at age mean 23.2, controlling for linear and quadratic age effects. Finally, we discuss the practical considerations of the use of total scores versus IRT scale scores in applications of the CFMT. PMID:25642930

  17. ICRS1, Proceedings of the First Radiation Shielding Symposium, Cambridge, UK 1958

    International Nuclear Information System (INIS)

    Goebelbecker, Hans-Juergen

    2008-01-01

    Description: The papers of the European Atomic Energy Society Symposium VI-58 on radiation shielding (ICRS1) held at Caius College, Cambridge England from 26 to 29 August 1958 are collected here for the first time in electronic form. This symposium was organised in connection with the Second Atoms for Peace Conference held in Geneva Held in Geneva from 1 to 13 September 1958. The Topics discussed covered gamma rays and neutron radiation; the Methods discussed were analytical approaches, semi-empirical Methods, simple computer codes, Monte Carlo method. Little quality nuclear data for shielding calculations was available and the presentations would concentrate on removal cross-sections and build-up factors. Experimental techniques in support to estimate the effective shielding properties of materials were discussed such as general experimental shielding techniques and experiments on neutron attenuation in different materials and on concrete as shield. Foil detectors for spectra measurements and determination of dose rates were mainly used. The typical issues addressed were gamma-heating, gamma spectra, neutron induced gammas, fission products gamma spectra, skyshine radiation and neutron ducts - streaming. Most participants were researchers from the naval and aeronautics sector

  18. Face recognition performance of individuals with Asperger syndrome on the Cambridge Face Memory Test.

    Science.gov (United States)

    Hedley, Darren; Brewer, Neil; Young, Robyn

    2011-12-01

    Although face recognition deficits in individuals with Autism Spectrum Disorder (ASD), including Asperger syndrome (AS), are widely acknowledged, the empirical evidence is mixed. This in part reflects the failure to use standardized and psychometrically sound tests. We contrasted standardized face recognition scores on the Cambridge Face Memory Test (CFMT) for 34 individuals with AS with those for 42, IQ-matched non-ASD individuals, and age-standardized scores from a large Australian cohort. We also examined the influence of IQ, autistic traits, and negative affect on face recognition performance. Overall, participants with AS performed significantly worse on the CFMT than the non-ASD participants and when evaluated against standardized test norms. However, while 24% of participants with AS presented with severe face recognition impairment (>2 SDs below the mean), many individuals performed at or above the typical level for their age: 53% scored within +/- 1 SD of the mean and 9% demonstrated superior performance (>1 SD above the mean). Regression analysis provided no evidence that IQ, autistic traits, or negative affect significantly influenced face recognition: diagnostic group membership was the only significant predictor of face recognition performance. In sum, face recognition performance in ASD is on a continuum, but with average levels significantly below non-ASD levels of performance. Copyright © 2011, International Society for Autism Research, Wiley-Liss, Inc.

  19. A Workshop on Environmental Technology Assessment Held at the University of Cambridge, England Held on 24-26 April, 1985,

    Science.gov (United States)

    1985-01-01

    for Air Pollutants J J Stukel Economic Issues in the Control of Air Pollution I M Torrens Theme 2 Water Treatment Megatrends in Water Treatment...Hahn Waste Water Treatment by Fixed Films in Biological Aerated Filters J Sibony Theme 4 Hazardous and Toxic Waste Management Technologies for...TECHNOLOGY ASSESSMENTS -c -e ne>±- a- University of Cambridge, England April 24-26, 1985 MEGATRENDS IN NATER TREATMENT TECHNOLOGIES F’. Fiessinaer, J

  20. Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq).

    Science.gov (United States)

    Gupta, Ravi; Allan, Richard P; Pundeer, Ashwini; Das, Sourav; Dhyani, Mohan; Goel, Deepak

    2015-01-01

    Restless legs syndrome also known as Willis-Ekbom's Disease (RLS/WED) is a common illness. Cambridge-Hopkins diagnostic questionnaire for RLS (CHRLSq) is a good diagnostic tool and can be used in the epidemiological studies. However, its Hindi version is not available. Thus, this study was conducted to translate and validate it in the Hindi speaking population. After obtaining the permission from the author of the CHRLSq, it was translated into Hindi language by two independent translators. After a series of forward and back translations, the finalized Hindi version was administered to two groups by one of the authors, who were blinded to the clinical diagnosis. First group consisted of RLS/WED patients, where diagnosis was made upon face to face interview and the other group - the control group included subjects with somatic symptoms disorders or exertional myalgia or chronic insomnia. Each group had 30 subjects. Diagnosis made on CHRLSq was compared with the clinical diagnosis. Analysis was done using Statistical Package for Social Sciences (SPSS) v 21.0. Descriptive statistics was calculated. Proportions were compared using chi-square test; whereas, categorical variables were compared using independent sample t-test. Sensitivity, specificity, and positive predictive value of the translated version of questionnaire were calculated. Average age was comparable between the cases and control group (RLS/WED = 39.1 ± 10.1 years vs 36.2 ± 11.4 years in controls; P = 0.29). Women outnumbered men in the RLS/WED group (87% in RLS/WED group vs 57% among controls; χ(2) = 6.64; P = 0.01). Both the sensitivity and specificity of the translated version was 83.3%. It had the positive predictive value of 86.6%. Hindi version of CHRLSq has positive predictive value of 87% and it can be used to diagnose RLS in Hindi speaking population.

  1. Hindi translation and validation of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq

    Directory of Open Access Journals (Sweden)

    Ravi Gupta

    2015-01-01

    Full Text Available Background: Restless legs syndrome also known as Willis-Ekbom′s Disease (RLS/WED is a common illness. Cambridge-Hopkins diagnostic questionnaire for RLS (CHRLSq is a good diagnostic tool and can be used in the epidemiological studies. However, its Hindi version is not available. Thus, this study was conducted to translate and validate it in the Hindi speaking population. Materials and Methods: After obtaining the permission from the author of the CHRLSq, it was translated into Hindi language by two independent translators. After a series of forward and back translations, the finalized Hindi version was administered to two groups by one of the authors, who were blinded to the clinical diagnosis. First group consisted of RLS/WED patients, where diagnosis was made upon face to face interview and the other group - the control group included subjects with somatic symptoms disorders or exertional myalgia or chronic insomnia. Each group had 30 subjects. Diagnosis made on CHRLSq was compared with the clinical diagnosis. Statistical Analysis: Analysis was done using Statistical Package for Social Sciences (SPSS v 21.0. Descriptive statistics was calculated. Proportions were compared using chi-square test; whereas, categorical variables were compared using independent sample t-test. Sensitivity, specificity, and positive predictive value of the translated version of questionnaire were calculated. Results: Average age was comparable between the cases and control group (RLS/WED = 39.1 ± 10.1 years vs 36.2 ± 11.4 years in controls; P = 0.29. Women outnumbered men in the RLS/WED group (87% in RLS/WED group vs 57% among controls; χ2 = 6.64; P = 0.01. Both the sensitivity and specificity of the translated version was 83.3%. It had the positive predictive value of 86.6%. Conclusion: Hindi version of CHRLSq has positive predictive value of 87% and it can be used to diagnose RLS in Hindi speaking population.

  2. Evaluation of a brief anti-stigma campaign in Cambridge: do short-term campaigns work?

    Directory of Open Access Journals (Sweden)

    Henderson Claire

    2010-06-01

    Full Text Available Abstract Background In view of the high costs of mass-media campaigns, it is important to understand whether it is possible for a media campaign to have significant population effects over a short period of time. This paper explores this question specifically in reference to stigma and discrimination against people with mental health problems using the Time to Change Cambridge anti-stigma campaign as an example. Methods 410 face-to-face interviews were performed pre, during and post campaign activity to assess campaign awareness and mental health-related knowledge, attitudes and behaviours. Results Although campaign awareness was not sustained following campaign activity, significant and sustained shifts occurred for mental health-related knowledge items. Specifically, there was a 24% (p If a friend had a mental health problem, I know what advice to give them to get professional help, following the campaign. Additionally, for the statement: Medication can be an effective treatment for people with mental health problems, there was a 10% rise (p = 0.05 in the proportion of interviewees responding 'agree' or 'strongly agree' following the campaign. These changes, however, were not evident for attitudinal or behaviour related questions. Conclusions Although these results only reflect the impact of one small scale campaign, these preliminary findings suggest several considerations for mass-media campaign development and evaluation strategies such as: (1 Aiming to influence outcomes pertaining to knowledge in the short term; (2 Planning realistic and targeted outcomes over the short, medium and long term during sustained campaigns; and (3 Monitoring indirect campaign effects such as social discourse or other social networking/contact in the evaluation.

  3. Depersonalization: An exploratory factor analysis of the Italian version of the Cambridge Depersonalization Scale.

    Science.gov (United States)

    Fagioli, F; Telesforo, L; Dell'Erba, A; Consolazione, M; Migliorini, V; Patanè, M; Boldrini, T; Graziani, R; Nicoletti, F; Fiori-Nastro, P

    2015-07-01

    "Depersonalization" (DP) is a common symptom in the general population and psychiatric patients (Michal et al., 2011 [1]). DP is characterized by an alteration in the experience of the self, so that one feels detached from his or her own mental processes or body (or from the world), feeling as being an outside observer of his or her own self, and loosing the experience of unity and identity (American Psychiatric Association, 2013 [2]). We performed an exploratory factor analysis of the Cambridge Depersonalization Scale Italian version (CDS-IV). We enrolled 149 inpatients and outpatients of psychiatric services located in two Italian regions, Lazio and Campania. Patients were aged between 15 and 65 and diagnosed with schizophrenic, depressive or anxiety disorders. Four factors accounted for 97.4% of the variance. Factor 1 (10, 24, 26, 1, 13, 23, 9, 2, 5, and 11), called "Detachment from the Self", captures experiences of detachment from actions and thoughts. Factor 2 (19, 20, 27, 3, 12, 23, 22, and 11), called "Anomalous bodily experiences", refers to unusual bodily experiences. Factor 3 (7, 28, 25, 6, 9, and 2), named "Numbing", describes the dampening of affects. Factor 4 (14, 17, and 16), named "Temporal blunting", refers to the subjective experience of time. We did not find any specific factor that refers to derealization; this suggests that the constructs of depersonalization/derealization (DP/DR) were strongly related to each other. Our results show that the constructs of DP/DR subsume several psychopathological dimensions; moreover, the above mentioned factors were broadly consistent with prior literature. Copyright © 2015. Published by Elsevier Inc.

  4. Evaluation of a brief anti-stigma campaign in Cambridge: do short-term campaigns work?

    Science.gov (United States)

    Evans-Lacko, Sara; London, Jillian; Little, Kirsty; Henderson, Claire; Thornicroft, Graham

    2010-06-14

    In view of the high costs of mass-media campaigns, it is important to understand whether it is possible for a media campaign to have significant population effects over a short period of time. This paper explores this question specifically in reference to stigma and discrimination against people with mental health problems using the Time to Change Cambridge anti-stigma campaign as an example. 410 face-to-face interviews were performed pre, during and post campaign activity to assess campaign awareness and mental health-related knowledge, attitudes and behaviours. Although campaign awareness was not sustained following campaign activity, significant and sustained shifts occurred for mental health-related knowledge items. Specifically, there was a 24% (p mental health problem, I know what advice to give them to get professional help, following the campaign. Additionally, for the statement: Medication can be an effective treatment for people with mental health problems, there was a 10% rise (p = 0.05) in the proportion of interviewees responding 'agree' or 'strongly agree' following the campaign. These changes, however, were not evident for attitudinal or behaviour related questions. Although these results only reflect the impact of one small scale campaign, these preliminary findings suggest several considerations for mass-media campaign development and evaluation strategies such as: (1) Aiming to influence outcomes pertaining to knowledge in the short term; (2) Planning realistic and targeted outcomes over the short, medium and long term during sustained campaigns; and (3) Monitoring indirect campaign effects such as social discourse or other social networking/contact in the evaluation.

  5. John Howard Marsden (1803–1891 First Disney Professor of Archaeology at the University of Cambridge 1851–1865

    Directory of Open Access Journals (Sweden)

    Michael Leach

    2007-05-01

    Full Text Available Although there were ten chairs of archaeology at universities in Germany, and one in France, by the mid-nineteenth century, in Great Britain it was the amateur societies and museums (the British Museum in particular that encouraged the study of this subject. In 1851 John Disney established the first university chair in Great Britain at Cambridge University. His proposal was initially received with considerable caution by the governing body of the university, and was only accepted by the narrowest margin of eight votes to seven. His agreement with the University of Cambridge stipulated that six lectures a year should be given on the subject of ‘Classical, Medieval, and other Antiquities, the Fine Arts and all matters and things connected therewith’ (Clark 1904, 222–225. However university archaeology was slow to establish its academic credibility nationally, and it was more than thirty years before Oxford University established its chair of classical archaeology. The Cambridge Board of Anthropological Studies, which included instruction in prehistoric archaeology, was not created until 1915, and as late as 1945 there were still only a few university lecturers in archaeology in Great Britain. It was not until 1946 that Oxford University appointed a Professor of Prehistoric Archaeology (Wilson 2002, 153; Daniel 1976, 6–12; Smith 2004, 4–5, 53–54.

  6. Crawford, Elisabeth: "Arrhenius: From Ionic Theory to the Greenhouse Effect" (Canton 1996); and Diana Barkan: "Walther Nernst and the Transition to Modern Physical Science" (Cambridge 1999) (book review)

    OpenAIRE

    Peter J. Ramberg

    2000-01-01

    book review of Crawford, Elisabeth: "Arrhenius: From Ionic Theory to the Greenhouse Effect" (Canton 1996); and Diana Barkan: "Walther Nernst and the Transition to Modern Physical Science" (Cambridge 1999)

  7. Mental health workshops delivered by medical students in Cambridge secondary schools: an evaluation of learning.

    Science.gov (United States)

    Bentham, Chloe; Daunt, Anna; Taylor, Stephanie; Simmons, Meinou

    2013-09-01

    For a group of medical students to design and deliver a mental health workshop in Cambridge secondary schools. Subsequently, to evaluate any improvements in pupils' knowledge of mental health issues, including knowledge of common mental illnesses, stigma and where to access help with mental health problems. A group of three medical students undertook a five week Student Selected Component to develop a mental health workshop in Spring 2013. The workshop was designed to include interactive components, such as role play, models and video. It was delivered to eight classes of 12-13 year old pupils across two local secondary schools, a total of 230 students. Questionnaires were completed before and after each workshop to test knowledge acquisition of mental health issues, stigma and where pupils could get help with mental health problems. Comparisons between data from the pre- and post-workshop questionnaires were made to assess learning. The responses from the questionnaires showed a global improvement in knowledge of mental health. This is highlighted by the increase in awareness of the prevalence of mental health problems amongst young people from 47.0% before the workshops to 97.8% after the workshops. The ability to identify symptoms of anxiety rose from 21.7% to 44.8% and the ability to identify depression rose from 29.0% to 53.5% respectively. Whilst only 15.2% pupils disagreed with a stigmatising statement about mental illness before the workshops, 61.3% pupils disagreed afterwards. The students were also better informed about how to access help and identified areas that they found useful to learn about. Comparison of the pre- and post-workshop questionnaires indicate that medical student-led workshops are an effective method for improving knowledge of mental health topics amongst 12-13 year old school pupils, as well as encouraging positive attitudes towards mental health. The project highlights a demand for mental health education in schools and brings to

  8. Hydrologic, Water-Quality, and Meteorological Data for the Cambridge, Massachusetts, Drinking-Water Source Area, Water Year 2006

    Science.gov (United States)

    Smith, Kirk P.

    2008-01-01

    Records of water quantity, water quality, and meteorological parameters were continuously collected from three reservoirs, two primary streams, and four subbasin tributaries in the Cambridge, Massachusetts, drinking-water source area during water year 2006 (October 2005 through September 2006). Water samples were collected during base-flow conditions and storms in the subbasins of the Cambridge Reservoir and Stony Brook Reservoir drainage areas and analyzed for dissolved calcium, sodium, chloride, and sulfate; total nitrogen and phosphorus; and polar pesticides and metabolites. These data were collected to assist watershed administrators in managing the drinking-water source area and to identify potential sources of contaminants and trends in contaminant loading to the water supply. Monthly reservoir contents for the Cambridge Reservoir varied from about 59 to 98 percent of capacity during water year 2006, while monthly reservoir contents for the Stony Brook Reservoir and the Fresh Pond Reservoir was maintained at greater than 83 and 94 percent of capacity, respectively. If water demand is assumed to be 15 million gallons per day by the city of Cambridge, the volume of water released from the Stony Brook Reservoir to the Charles River during the 2006 water year is equivalent to an annual water surplus of about 127 percent. Recorded precipitation in the source area was about 16 percent greater for the 2006 water year than for the previous water year and was between 12 and 73 percent greater than for any recorded amount since water year 2002. The monthly mean specific-conductance values for all continuously monitored stations within the drinking-water source area were generally within the range of historical data collected since water year 1997, and in many cases were less than the historical medians. The annual mean specific conductance of 738 uS/cm (microsiemens per centimeter) for water discharged from the Cambridge Reservoir was nearly identical to the annual

  9. Diagnosis of mild chronic pancreatitis (Cambridge classification): comparative study using secretin injection-magnetic resonance cholangiopancreatography and endoscopic retrograde pancreatography.

    Science.gov (United States)

    Sai, Jin-Kan; Suyama, Masafumi; Kubokawa, Yoshihiro; Watanabe, Sumio

    2008-02-28

    To investigate the usefulness of secretin injection-MRCP for the diagnosis of mild chronic pancreatitis. Sixteen patients having mild chronic pancreatitis according to the Cambridge classification and 12 control subjects with no abnormal findings on the pancreatogram were examined for the diagnostic accuracy of secretin injection-MRCP regarding abnormal branch pancreatic ducts associated with mild chronic pancreatitis (Cambridge Classification), using endoscopic retrograde cholangiopancreatography (ERCP) for comparison. The sensitivity and specificity for abnormal branch pancreatic ducts determined by two reviewers were respectively 55%-63% and 75%-83% in the head, 57%-64% and 82%-83% in the body, and 44%-44% and 72%-76% in the tail of the pancreas. The sensitivity and specificity for mild chronic pancreatitis were 56%-63% and 92%-92%, respectively. Interobserver agreement (kappa statistics) concerning the diagnosis of an abnormal branch pancreatic duct and of mild chronic pancreatitis was good to excellent. Secretin injection-MRCP might be useful for the diagnosis of mild chronic pancreatitis.

  10. The Cambridge Face Memory Test for Children (CFMT-C): a new tool for measuring face recognition skills in childhood.

    Science.gov (United States)

    Croydon, Abigail; Pimperton, Hannah; Ewing, Louise; Duchaine, Brad C; Pellicano, Elizabeth

    2014-09-01

    Face recognition ability follows a lengthy developmental course, not reaching maturity until well into adulthood. Valid and reliable assessments of face recognition memory ability are necessary to examine patterns of ability and disability in face processing, yet there is a dearth of such assessments for children. We modified a well-known test of face memory in adults, the Cambridge Face Memory Test (Duchaine & Nakayama, 2006, Neuropsychologia, 44, 576-585), to make it developmentally appropriate for children. To establish its utility, we administered either the upright or inverted versions of the computerised Cambridge Face Memory Test - Children (CFMT-C) to 401 children aged between 5 and 12 years. Our results show that the CFMT-C is sufficiently sensitive to demonstrate age-related gains in the recognition of unfamiliar upright and inverted faces, does not suffer from ceiling or floor effects, generates robust inversion effects, and is capable of detecting difficulties in face memory in children diagnosed with autism. Together, these findings indicate that the CFMT-C constitutes a new valid assessment tool for children's face recognition skills. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Hydrologic, Water-Quality, and Meteorological Data for the Cambridge, Massachusetts, Drinking-Water Source Area, Water Year 2005

    Science.gov (United States)

    Smith, Kirk P.

    2007-01-01

    Records of water quantity, water quality, and meteorological parameters were continuously collected from three reservoirs, two primary streams, and four subbasin tributaries in the Cambridge, Massachusetts, drinking-water source area during water year 2005 (October 2004 through September 2005). Water samples were collected during base-flow conditions and storms in the subbasins of the Cambridge Reservoir and Stony Brook Reservoir drainage areas and analyzed for selected elements, organic constituents, suspended sediment, and Escherichia coli bacteria. These data were collected to assist watershed administrators in managing the drinking-water source area and to identify potential sources of contaminants and trends in contaminant loading to the water supply. Monthly reservoir capacities for the Cambridge Reservoir varied from about 59 to 98 percent during water year 2005, while monthly reservoir capacities for the Stony Brook Reservoir and the Fresh Pond Reservoir were maintained at capacities greater than 84 and 96 percent, respectively. Assuming a water demand of 15 million gallons per day by the city of Cambridge, the volume of water released from the Stony Brook Reservoir to the Charles River during the 2005 water year is equivalent to an annual water surplus of about 119 percent. Recorded precipitation in the source area for the 2005 water year was within 2 inches of the total annual precipitation for the previous 2 water years. The monthly mean specific conductances for the outflow of the Cambridge Reservoir were similar to historical monthly mean values. However, monthly mean specific conductances for Stony Brook near Route 20, in Waltham (U.S. Geological Survey station 01104460), which is the principal tributary feeding the Stony Brook Reservoir, were generally higher than the medians of the monthly mean specific conductances for the period of record. Similarly, monthly mean specific conductances for a small tributary to Stony Brook (U.S. Geological Survey

  12. Healthy travel and the socio-economic structure of car commuting in Cambridge, UK: a mixed-methods analysis.

    Science.gov (United States)

    Goodman, Anna; Guell, Cornelia; Panter, Jenna; Jones, Natalia R; Ogilvie, David

    2012-06-01

    Car use is associated with substantial health and environmental costs but research in deprived populations indicates that car access may also promote psychosocial well-being within car-oriented environments. This mixed-method (quantitative and qualitative) study examined this issue in a more affluent setting, investigating the socio-economic structure of car commuting in Cambridge, UK. Our analyses involved integrating self-reported questionnaire data from 1142 participants in the Commuting and Health in Cambridge study (collected in 2009) and in-depth interviews with 50 participants (collected 2009-2010). Even in Britain's leading 'cycling city', cars were a key resource in bridging the gap between individuals' desires and their circumstances. This applied both to long-term life goals such as home ownership and to shorter-term challenges such as illness. Yet car commuting was also subject to constraints, with rush hour traffic pushing drivers to start work earlier and with restrictions on, or charges for, workplace parking pushing drivers towards multimodal journeys (e.g. driving to a 'park-and-ride' site then walking). These patterns of car commuting were socio-economically structured in several ways. First, the gradient of housing costs made living near Cambridge more expensive, affecting who could 'afford' to cycle and perhaps making cycling the more salient local marker of Bourdieu's class distinction. Nevertheless, cars were generally affordable in this relatively affluent, highly-educated population, reducing the barrier which distance posed to labour-force participation. Finally, having the option of starting work early required flexible hours, a form of job control which in Britain is more common among higher occupational classes. Following a social model of disability, we conclude that socio-economic advantage can make car-oriented environments less disabling via both greater affluence and greater job control, and in ways manifested across the full socio

  13. Rifkin broadens challenge in biotech.

    Science.gov (United States)

    Sun, M

    1984-07-20

    Jeremy Rifkin has petitioned a U.S. district court, the National Institutes of Health, and the Environmental Protection Agency in a campaign to prevent private companies, as well as universities, from releasing genetically modified organisms into the environment until the possible environmental impact of these experiments has been analyzed. Rifkin is seeking to stop Advanced Genetic Sciences and Cetus Corporation from conducting field tests respectively of modified frost-resistant bacteria and disease-resistant plants. His efforts have already led scientists at Stanford University to postpone voluntarily the planting of corn seed containing recombinant DNA.

  14. Space Biotech: Hindsight, Insight, Foresight

    Science.gov (United States)

    Harper, Lynn

    2015-01-01

    Over the past forty years, microgravity has inspired and enabled applications in a wide range of sectors including medicine, materials, computers, communications, and national defense. Trends show that demand for high-tech solutions is increasing in these sectors, solutions that require higher resolution, greater precision, novel materials, innovative processes, and more sophisticated tools. These are areas where microgravity can offer unique capabilities for innovation. The Emerging Space Office (ESO) has engaged in multiple studies over the past year that have found that microgravity RD is one of the most promising technology areas for contributing to economic growth and to NASAs mission. The focus of these studies was on terrestrial markets rather than NASA applications, applied research rather than basic research, and commercial rather than academic investigators. There have been more success stories than are generally appreciated and there are significant areas of promising future potential. Many of the problems that have limited commercial microgravity development in the past are being solved. Microgravity research and development (RD) requires iteration and learning, as rapidly as possible. New technologies enable high throughput and rapid data collection in increasingly small payloads. The International Space Station is in orbit and provides a laboratory that is available 247 at least until 2024. Frequent flights by commercial space providers to and from the ISS now enable the fast learning cycles needed by high-tech industries. Launch costs are decreasing and the ability to return payloads to Earth is increasing. New commercial space laboratories, such as those being developed by SpaceX and Bigelow Aerospace, are in the final stages of development and testing. This ecosystem for microgravity RD has never been available before. These are game-changer conditions for attracting high-tech industries to space for terrestrial, as well as NASA, applications. However, few know that these capabilities are available or how to use them. In aggregate, the potential value for new applications from microgravity RD over the next ten years could add billions of dollars per year in terrestrial applications to the future economy, create new jobs, and generate a wide range of public benefits in medical advances, while broadening the customer base for the emerging space industry.

  15. Superpartner Mass Measurement Technique using 1D Orthogonal Decompositions of the Cambridge Transverse Mass Variable MT2

    Science.gov (United States)

    Konar, Partha; Kong, Kyoungchul; Matchev, Konstantin T.; Park, Myeonghun

    2010-07-01

    We propose a new model-independent technique for mass measurements in missing energy events at hadron colliders. We illustrate our method with the most challenging case of a single-step decay chain. We consider inclusive same-sign chargino pair production in supersymmetry, followed by leptonic decays to sneutrinos χ+χ+→ℓ+ℓ'+ν˜ℓν˜ℓ' and invisible decays ν˜ℓ→νℓχ˜10. We introduce two one-dimensional decompositions of the Cambridge MT2 variable: MT2∥ and MT2⊥, on the direction of the upstream transverse momentum P→T and the direction orthogonal to it, respectively. We show that the sneutrino mass Mc can be measured directly by minimizing the number of events N(M˜c) in which MT2 exceeds a certain threshold, conveniently measured from the end point MT2⊥max⁡(M˜c).

  16. A teaching skills assessment tool inspired by the Calgary-Cambridge model and the patient-centered approach.

    Science.gov (United States)

    Sommer, Johanna; Lanier, Cédric; Perron, Noelle Junod; Nendaz, Mathieu; Clavet, Diane; Audétat, Marie-Claude

    2016-04-01

    The aim of this study was to develop a descriptive tool for peer review of clinical teaching skills. Two analogies framed our research: (1) between the patient-centered and the learner-centered approach; (2) between the structures of clinical encounters (Calgary-Cambridge communication model) and teaching sessions. During the course of one year, each step of the action research was carried out in collaboration with twelve clinical teachers from an outpatient general internal medicine clinic and with three experts in medical education. The content validation consisted of a literature review, expert opinion and the participatory research process. Interrater reliability was evaluated by three clinical teachers coding thirty audiotaped standardized learner-teacher interactions. This tool contains sixteen items covering the process and content of clinical supervisions. Descriptors define the expected teaching behaviors for three levels of competence. Interrater reliability was significant for eleven items (Kendall's coefficient pteaching skills. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  17. Correlation of 0.67um scatter with local stress in Ge impacted with the modified Cambridge liquid jet device

    Science.gov (United States)

    Wilson, Michael; Price, D.; Strohecker, Steve

    1994-09-01

    Germanium witness samples were impacted with the NAWCADWAR modified Cambridge liquid jet device introducing varying levels of damage about the center of each sample. Surface damage statistics were collected, scatter measurements were made at 0.67 micrometers and the samples were failed in tension using a bi-axial flexure test setup. The level and character of the damage was correlated with the reflected scatter measurements as a function of local stress and flaw size distribution. Bi-axial flexure data was analyzed to predict fracture stress and the probability of failure of the germanium samples. The mechanical data were then correlated with the scatter data in order to correlate the BRDF with the material failure. The BRDF measurements were taken in several different orientations in order to study the differences in scatter character for the in-plane and out-of-plane conditions.

  18. Money Now, Money Later: Linking Time Discounting and Criminal Convictions in the Cambridge Study in Delinquent Development.

    Science.gov (United States)

    Piquero, Alex R; Farrington, David P; Jennings, Wesley G

    2018-04-01

    Two prominent criminological theories offer time discounting, or the preference for an immediate reward over a later one, as a central part of understanding involvement in criminal activity. Yet, there exist only a few studies investigating this issue, and they are limited in a few respects. The current study extends prior work in this area by using multiple measures of time discounting collected at three different periods of the life course to examine the link to criminal offending into late middle adulthood in the Cambridge Study in Delinquent Development. Results show that greater time discounting is positively related to a higher number of criminal convictions by late middle adulthood, and this effect remains after controlling for early life-course individual and environmental risk in a multivariate framework. Study limitations and implications are also discussed.

  19. International Organization of Standardization (ISO) and Cambridge Filter Test (CFT) Smoking Regimen Data Comparisons in Tobacco Product Marketing Applications.

    Science.gov (United States)

    Chae, Changyu; Walters, Matthew J; Holman, Matthew R

    2017-07-01

    We investigated the differences in TNCO (tar, nicotine, and carbon monoxide) smoke yields generated under the International Organization of Standardization (ISO) and Federal Trade Commission (FTC) Cambridge Filter Test (CFT) smoking regimens. Twenty-nine commercial cigarette products from the US marketplace were acquired in 2015 and tested by measuring the TNCO smoke yields generated under these 2 nonintense smoking regimens. Data obtained demonstrated a linear relationship between the TNCO yields produced under the 2 smoking regimens (R 2 > 0.99). TNCO yields produced by each product were higher under the CFT smoking regimen than the ISO smoking regimen. We found that tar, nicotine, and carbon monoxide yields were consistently 10% to 13% higher under the CFT smoking regimen than under the ISO smoking regimen. This strong correlation indicates that the 2 smoking regimens can be used to apply a correlation correction to CFT TNCO data and allow its comparison to ISO TNCO data in tobacco product marketing applications.

  20. Goals for the Correlation of Elementary Science and Mathematics; The Report of the Cambridge Conference on the Correlation of Science and Mathematics in Schools.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    This is The Report of the 1967 Cambridge Conference on the Correlation of Science and Mathematics in the Schools. It is addressed to professionals in education, and is designed to stimulate dialogue among them concerning the mathematics-science curriculum. The report is organized in five chapters, each dealing respectively with (1) educational…

  1. Particle Size Distribution of E-Cigarette Aerosols and the Relationship to Cambridge Filter Pad Collection Efficiency

    Directory of Open Access Journals (Sweden)

    Alderman Steven L.

    2015-01-01

    Full Text Available The relatively volatile nature of the particulate matter fraction of e-cigarette aerosols presents an experimental challenge with regard to particle size distribution measure-ments. This is particularly true for instruments requiring a high degree of aerosol dilution. This was illustrated in a previous study, where average particle diameters in the 10-50 nm range were determined by a high-dilution, electrical mobility method. Total particulate matter (TPM masses calculated based on those diameters were orders of magnitude smaller than gravimetrically determined TPM. This discrepancy was believed to result from almost complete particle evaporation at the dilution levels of the electrical mobility analysis. The same study described a spectral transmission measurement of e-cigarette particle size in an undiluted state, and reported particles from 210-380 nm count median diameter. Observed particle number concentrations were in the 109 particles/cm3 range. Additional particle size measurements described here also found e-cigarette particle size to be in the 260-320 nm count median diameter range. Cambridge filter pads have been used for decades to determine TPM yields of tobacco burning cigarettes, and collection of e-cigarette TPM by fibrous filters is predicted to be a highly efficient process over a wide range of filtration flow rates. The results presented in this work provide support for this hypothesis.

  2. Applicability of the Calgary-Cambridge Guide to Dog and Cat Owners for Teaching Veterinary Clinical Communications.

    Science.gov (United States)

    Englar, Ryane E; Williams, Melanie; Weingand, Kurt

    2016-01-01

    Effective communication in health care benefits patients. Medical and veterinary schools not only have a responsibility to teach communication skills, the American Veterinary Medical Association (AVMA) Council on Education (COE) requires that communication be taught in all accredited colleges of veterinary medicine. However, the best strategy for designing a communications curriculum is unclear. The Calgary-Cambridge Guide (CCG) is one of many models developed in human medicine as an evidence-based approach to structuring the clinical consultation through 71 communication skills. The model has been revised by Radford et al. (2006) for use in veterinary curricula; however, the best approach for veterinary educators to teach communication remains to be determined. This qualitative study investigated if one adaptation of the CCG currently taught at Midwestern University College of Veterinary Medicine (MWU CVM) fulfills client expectations of what constitutes clinically effective communication. Two focus groups (cat owners and dog owners) were conducted with a total of 13 participants to identify common themes in veterinary communication. Participants compared communication skills they valued to those taught by MWU CVM. The results indicated that while the CCG skills that MWU CVM adopted are applicable to cat and dog owners, they are not comprehensive. Participants expressed the need to expand the skillset to include compassionate transparency and unconditional positive regard. Participants also expressed different communication needs that were attributed to the species of companion animal owned.

  3. Hukum Lingkungan dan Pertanggungjawaban Strict Liability dalam Sistem Hukum Common Law (Studi Kasus Cambridge Water Co. Ltd v. Eastern Countries Leather Plc

    Directory of Open Access Journals (Sweden)

    Mahfud Mahfud

    2010-12-01

    Full Text Available ABSTRACT: The possibilities for pollution control still offered today Blackburn J.’s celebrated rule of strict liability, now almost 130 years old, has ensured its continuing popularity. There can be few tort lawyers, however, who have not increasingly wondered how much time should be devoted to a case which has received little judicial attention in recent years, and which was last subjected to detailed consideration by the House of Lords nearly 50 years ago, until, that is, the much-published decision of the House of Lords in Cambridge Water Co. Ltd v. Eastern Countries Leather Plc.   (Environmental Law and The Strict Liability Application In the Common Law System (The Case Study of Cambridge Water Co. Ltd V. Eastern Countries Leather Plc

  4. Reply to L.M. Brown et al. “Brief history of the Cambridge STEM aberration correction project and its progeny” in Ultramicroscopy 157, 88 (2015)

    Energy Technology Data Exchange (ETDEWEB)

    Urban, K.W., E-mail: k.urban@fz-juelich.de [Peter Grünberg Institute, Forschungszentrum Jülich, Jülich-Aachen Research Alliance (JARA), and Ernst Ruska Centre for Microscopy and Spectroscopy with Electrons, 52425 Jülich (Germany); Rose, H. [Materialwissenschaftliche Elektronenmikroskopie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm (Germany)

    2016-02-15

    We comment on a Short Communication recently published in Ultramicroscopy in which Brown et al. criticize our description of the time sequence of events in the development of aberration correction systems in electron optics during the 1990s put forward in the introduction to the Ultramicroscopy April 2015 Special Issue. We present an analysis of the published literature furnishing evidence that our description is correct. - Highlights: • We scrutinize assertions made on the evolution of Cambridge Cs corrector project. • References [22-24] do not demonstrate improvement of resolution by Cs correction. • According to literature such improvement is only shown in reference [10] in 2001. • Corresponding evidence was published by Heidelberg project already in 1998. • The Heidelberg Cs corrector project antedates the Cambridge project by 3 years.

  5. Reply to L.M. Brown et al. “Brief history of the Cambridge STEM aberration correction project and its progeny” in Ultramicroscopy 157, 88 (2015)

    International Nuclear Information System (INIS)

    Urban, K.W.; Rose, H.

    2016-01-01

    We comment on a Short Communication recently published in Ultramicroscopy in which Brown et al. criticize our description of the time sequence of events in the development of aberration correction systems in electron optics during the 1990s put forward in the introduction to the Ultramicroscopy April 2015 Special Issue. We present an analysis of the published literature furnishing evidence that our description is correct. - Highlights: • We scrutinize assertions made on the evolution of Cambridge Cs corrector project. • References [22-24] do not demonstrate improvement of resolution by Cs correction. • According to literature such improvement is only shown in reference [10] in 2001. • Corresponding evidence was published by Heidelberg project already in 1998. • The Heidelberg Cs corrector project antedates the Cambridge project by 3 years.

  6. Surface-water, water-quality, and meteorological data for the Cambridge, Massachusetts, drinking-water source area, water years 2007-08

    Science.gov (United States)

    Smith, Kirk P.

    2011-01-01

    Records of water quantity, water quality, and meteorological parameters were continuously collected from three reservoirs, two primary streams, and five subbasin tributaries in the Cambridge, Massachusetts, drinking-water source area during water years 2007-08 (October 2006 through September 2008). Water samples were collected during base-flow conditions and storms in the Cambridge Reservoir and Stony Brook Reservoir drainage areas and analyzed for dissolved calcium, sodium, chloride, and sulfate; total nitrogen and phosphorus; and polar pesticides and metabolites. Composite samples of stormwater also were analyzed for concentrations of total petroleum hydrocarbons and suspended sediment in one subbasin in the Stony Brook Reservoir drainage basin. These data were collected to assist watershed administrators in managing the drinking-water source area and to identify potential sources of contaminants and trends in contaminant loading to the water supply.

  7. EDITORIAL: Proceedings of the 12th Gravitational Wave Data Analysis Workshop (GWDAW 12), Cambridge, MA, USA, 13 16 December 2007

    Science.gov (United States)

    Hughes, S.; Katsavounidis, E.

    2008-09-01

    It was a great pleasure and an honor for us to host the 12th Gravitational Wave Data Analysis Workshop (GWDAW) at MIT and the LIGO Laboratory in Cambridge, Massachusetts, the place where this workshop series started in 1996. This time the conference was held at the conference facilities of the Royal Sonesta Hotel in Cambridge from 13 16 December, 2007. This 12th GWDAW found us with the ground interferometers having just completed their most sensitive search for gravitational waves and as they were starting their preparation to bring online and/or propose more sensitive instruments. Resonant mass detectors continued to observe the gravitational wave sky with instruments that have been operating now for many years. LISA, the Laser Interferometer Space Antenna, was recently reviewed by NASA's Beyond Einstein Program Assessment Committee (BEPAC) convened by the National Research Council (NRC) and found that 'on purely scientific grounds LISA is the mission that is the most promising and least scientifically risky…thus, the committee gave LISA its highest scientific ranking'. Even so, JDEM, the Joint Dark Energy Mission, was identified to go first, with LISA following a few years after. New methods, analysis ideas, results from the analysis of data collected by the instruments, as well as Mock Data Challenges for LISA were reported in this conference. While data from the most recent runs of the instruments are still being analyzed, the first upper limit results show how even non-detection statements can be interesting astrophysics. Beyond these traditional aspects of GWDAW though, for the first time in this workshop we tried to bring the non-gravitational wave physics and astronomy community on board in order to present, discuss and propose ways to work together as we pursue the first detection of gravitational waves and as we hope to transition to gravitational wave astronomy in the near future. Overview talks by colleagues leading observations in the electromagnetic

  8. Neuwirth RJ, Svetlicinii A and De Castro Halis D (eds) The BRICS-Lawyers' Guide to Global Cooperation (Cambridge University Press 2017)

    OpenAIRE

    Sucker, F

    2018-01-01

    This contribution reviews the book The BRICS-Lawyers' Guide to Global Cooperation edited by Rostam J Neuwirth, Alexandr Svetlicinii and Denis De Castro Halis. It was published by Cambridge University Press in 2017, and deals with aspects of international trade and development involving the BRICS area -Brazil, Russia, India, China and South Africa. It is described as a unique reference book for academics, governmental officials, legal professionals, business executives, researchers and students.

  9. Learning lessons from the past: A historical exploration of a century of business education at Oxford and Cambridge (1900s-2000s)

    OpenAIRE

    Arena , Lise; Dang , Rani Jeanne

    2010-01-01

    This research aims to identify a set of generative mechanisms which are shared by business schools' process of development in their search for strategic comparative advantage. We use a processual approach (Pettigrew, 1997) based on two detailed historical studies supported by unexplored archival data and interviews: the case of the Saïd Business School at the University of Oxford and the case of the Judge Business School at the University of Cambridge (1990s - 2000s). Preliminary results indi...

  10. Multiphase composition changes and reactive oxygen species formation during limonene oxidation in the new Cambridge Atmospheric Simulation Chamber (CASC)

    Science.gov (United States)

    Gallimore, Peter J.; Mahon, Brendan M.; Wragg, Francis P. H.; Fuller, Stephen J.; Giorio, Chiara; Kourtchev, Ivan; Kalberer, Markus

    2017-08-01

    The chemical composition of organic aerosols influences their impacts on human health and the climate system. Aerosol formation from gas-to-particle conversion and in-particle reaction was studied for the oxidation of limonene in a new facility, the Cambridge Atmospheric Simulation Chamber (CASC). Health-relevant oxidising organic species produced during secondary organic aerosol (SOA) formation were quantified in real time using an Online Particle-bound Reactive Oxygen Species Instrument (OPROSI). Two categories of reactive oxygen species (ROS) were identified based on time series analysis: a short-lived component produced during precursor ozonolysis with a lifetime of the order of minutes, and a stable component that was long-lived on the experiment timescale (˜ 4 h). Individual organic species were monitored continuously over this time using Extractive Electrospray Ionisation (EESI) Mass Spectrometry (MS) for the particle phase and Proton Transfer Reaction (PTR) MS for the gas phase. Many first-generation oxidation products are unsaturated, and we observed multiphase aging via further ozonolysis reactions. Volatile products such as C9H14O (limonaketone) and C10H16O2 (limonaldehyde) were observed in the gas phase early in the experiment, before reacting again with ozone. Loss of C10H16O4 (7-hydroxy limononic acid) from the particle phase was surprisingly slow. A combination of reduced C = C reactivity and viscous particle formation (relative to other SOA systems) may explain this, and both scenarios were tested in the Pretty Good Aerosol Model (PG-AM). A range of characterisation measurements were also carried out to benchmark the chamber against existing facilities. This work demonstrates the utility of CASC, particularly for understanding the reactivity and health-relevant properties of organic aerosols using novel, highly time-resolved techniques.

  11. Educational outcomes of the Harvard Medical School-Cambridge integrated clerkship: a way forward for medical education.

    Science.gov (United States)

    Hirsh, David; Gaufberg, Elizabeth; Ogur, Barbara; Cohen, Pieter; Krupat, Edward; Cox, Malcolm; Pelletier, Stephen; Bor, David

    2012-05-01

    The authors report data from the Harvard Medical School-Cambridge Integrated Clerkship (CIC), a model of medical education in which students' entire third year consists of a longitudinal, integrated curriculum. The authors compare the knowledge, skills, and attitudes of students completing the CIC with those of students completing traditional third-year clerkships. The authors compared 27 students completing the first three years of the CIC (2004-2007) with 45 students completing clerkships at other Harvard teaching hospitals during the same period. At baseline, no significant between-group differences existed (Medical College Admission Test and Step 1 scores, second-year objective structured clinical examination [OSCE] performance, attitudes toward patient-centered care, and plans for future practice) in any year. The authors compared students' National Board of Medical Examiners Subject and Step 2 Clinical Knowledge scores, OSCE performance, perceptions of the learning environment, and attitudes toward patient-centeredness. CIC students performed as well as or better than their traditionally trained peers on measures of content knowledge and clinical skills. CIC students expressed higher satisfaction with the learning environment, more confidence in dealing with numerous domains of patient care, and a stronger sense of patient-centeredness. CIC students are at least as well as and in several ways better prepared than their peers. CIC students also demonstrate richer perspectives on the course of illness, more insight into social determinants of illness and recovery, and increased commitment to patients. These data suggest that longitudinal integrated clerkships offer students important intellectual, professional, and personal benefits.

  12. Risk factors for dating violence versus cohabiting violence: Results from the third generation of the Cambridge Study in Delinquent Development.

    Science.gov (United States)

    Theobald, Delphine; Farrington, David P; Ttofi, Maria M; Crago, Rebecca V

    2016-10-01

    Dating violence is an important problem. Evidence suggests that women are more likely to perpetrate dating violence. The present study investigates the prevalence of dating violence compared with cohabiting violence in a community sample of men and women and assesses to what extent child and adolescent explanatory factors predict this behaviour. A secondary aim is to construct a risk score for dating violence based on the strongest risk factors. The Cambridge Study in Delinquent Development is a prospective longitudinal survey of 411 men (generation 2) born in the 1950s in an inner London area. Most recently, their sons and daughters [generation 3 (G3)] have been interviewed regarding their perpetration of dating and cohabiting violence, utilising the Conflict Tactics Scale. Risk factors were measured in four domains (family, parental, socio-economic and individual). A larger proportion of women than men perpetrated at least one act of violence towards their dating partner (36.4 vs 21.7%). There was a similar pattern for cohabiting violence (39.6 vs 21.4%). A number of risk factors were significantly associated with the perpetration of dating violence. For G3 women, these included a convicted father, parental conflict, large family size and poor housing. For G3 men, these included having a young father or mother, separation from the father before age 16, early school leaving, frequent truancy and having a criminal conviction. A risk score for both men and women, based on 10 risk factors, significantly predicted dating violence. Risk factors from four domains were important in predicting dating violence, but they were different for G3 men and women. It may be important to consider different risk factors and different risk assessments for male compared with female perpetration of dating violence. Early identification and interventions are recommended. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  13. Potential reductions of street solids and phosphorus in urban watersheds from street cleaning, Cambridge, Massachusetts, 2009-11

    Science.gov (United States)

    Sorenson, Jason R.

    2013-01-01

    Material accumulating and washing off urban street surfaces and ultimately into stormwater drainage systems represents a substantial nonpoint source of solids, phosphorus, and other constituent loading to waterways in urban areas. Cost and lack of usable space limit the type and number of structural stormwater source controls available to municipalities and other public managers. Non-structural source controls such as street cleaning are commonly used by cities and towns for construction, maintenance and aesthetics, and may reduce contaminant loading to waterways. Effectiveness of street cleaning is highly variable and potential improvements to water quality are not fully understood. In 2009, the U.S. Geological Survey, in cooperation with the Massachusetts Department of Environmental Protection, the U.S. Environmental Protection Agency, and the city of Cambridge, Massachusetts, and initiated a study to better understand the physical and chemical nature of the organic and inorganic solid material on street surfaces, evaluate the performance of a street cleaner at removing street solids, and make use of the Source Loading and Management Model (SLAMM) to estimate potential reductions in solid and phosphorus loading to the lower Charles River from various street-cleaning technologies and frequencies. Average yield of material on streets collected between May and December 2010, was determined to be about 740 pounds per curb-mile on streets in multifamily land use and about 522 pounds per curb-mile on commercial land-use streets. At the end-of-winter in March 2011, about 2,609 and 4,788 pounds per curb-mile on average were collected from streets in multifamily and commercial land-use types, respectively. About 86 percent of the total street-solid yield from multifamily and commercial land-use streets was greater than or equal to 0.125 millimeters in diameter (or very fine sand). Observations of street-solid distribution across the entire street width indicated that as

  14. Nitroxide stable radicals interacting as Lewis bases in hydrogen bonds: A search in the Cambridge structural data base for intermolecular contacts

    Science.gov (United States)

    Alkorta, Ibon; Elguero, José; Elguero, Eric

    2017-11-01

    1125 X-ray structures of nitroxide free radicals presenting intermolecular hydrogen bonds have been reported in the Cambridge Structural Database. We will report in this paper a qualitative and quantitative analysis of these bonds. The observation in some plots of an excluded region was statistically analyzed using convex hull and kernel smooting methodologies. A theoretical study at the MP2 level with different basis has been carried out indicating that the nitronyl nitroxide radicals (five electrons) lie just in between nitroso compounds (four electrons) and amine N-oxides (six electrons) as far as hydrogen-bond basicity is concerned.

  15. Loads and yields of deicing compounds and total phosphorus in the Cambridge drinking-water source area, Massachusetts, water years 2009–15

    Science.gov (United States)

    Smith, Kirk P.

    2017-09-12

    The source water area for the drinking-water supply of the city of Cambridge, Massachusetts, encompasses major transportation corridors, as well as large areas of light industrial, commercial, and residential land use. Because of the large amount of roadway in the drinking-water source area, the Cambridge water supply is affected by the usage of deicing compounds and by other constituents that are flushed from such impervious areas. The U.S. Geological Survey (USGS) has monitored surface-water quality in the Cambridge Reservoir and Stony Brook Reservoir Basins, which compose the drinking-water source area, since 1997 (water year 1998) through continuous monitoring and the collection of stream-flow samples.In a study conducted by the USGS, in cooperation with the City of Cambridge Water Department, concentrations and loads of calcium (Ca), chloride (Cl), magnesium (Mg), sodium (Na), and sulfate (SO4) were estimated from continuous records of specific conductance and streamflow for streams and tributaries at 10 continuous water-quality monitoring stations. These data were used to characterize current (2015) water-quality conditions, estimate loads and yields, and describe trends in Cl and Na in the tributaries and main-stem streams in the Cambridge Reservoir and Stony Brook Reservoir Basins. These data also were used to describe how stream-water quality is related to various basin characteristics and provide information to guide future management of the drinking-water source area.Water samples from 2009–15 were analyzed for physical properties and concentrations of Ca, Cl, Mg, Na, potassium (K), SO4, and total phosphorus (TP). Values of physical properties and constituent concentrations varied widely, particularly in composite samples of stormflow from tributaries that have high percentages of constructed impervious areas. Median concentrations of Ca, Cl, Mg, Na, and K in samples collected from the tributaries in the Cambridge Reservoir Basin (27.2, 273, 4.7, 154

  16. The ADDITION-Cambridge trial protocol: a cluster – randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients

    Directory of Open Access Journals (Sweden)

    Kinmonth Ann

    2009-05-01

    Full Text Available Abstract Background The increasing prevalence of type 2 diabetes poses a major public health challenge. Population-based screening and early treatment for type 2 diabetes could reduce this growing burden. However, the benefits of such a strategy remain uncertain. Methods and design The ADDITION-Cambridge study aims to evaluate the effectiveness and cost-effectiveness of (i a stepwise screening strategy for type 2 diabetes; and (ii intensive multifactorial treatment for people with screen-detected diabetes in primary care. 63 practices in the East Anglia region participated. Three undertook the pilot study, 33 were allocated to three groups: no screening (control, screening followed by intensive treatment (IT and screening plus routine care (RC in an unbalanced (1:3:3 randomisation. The remaining 27 practices were randomly allocated to IT and RC. A risk score incorporating routine practice data was used to identify people aged 40–69 years at high-risk of undiagnosed diabetes. In the screening practices, high-risk individuals were invited to take part in a stepwise screening programme. In the IT group, diabetes treatment is optimised through guidelines, target-led multifactorial treatment, audit, feedback, and academic detailing for practice teams, alongside provision of educational materials for newly diagnosed participants. Primary endpoints are modelled cardiovascular risk at one year, and cardiovascular mortality and morbidity at five years after diagnosis of diabetes. Secondary endpoints include all-cause mortality, development of renal and visual impairment, peripheral neuropathy, health service costs, self-reported quality of life, functional status and health utility. Impact of the screening programme at the population level is also assessed through measures of mortality, cardiovascular morbidity, health status and health service use among high-risk individuals. Discussion ADDITION-Cambridge is conducted in a defined high-risk group

  17. 40-Godišnjica institucije Cambridge Crystallographic Data Centre posvećene pohranjivanju podataka o molekularnim i kristalnim strukturama -

    Directory of Open Access Journals (Sweden)

    Molčanov, K.

    2006-06-01

    Full Text Available The article is dedicated to 40th anniversary of The Cambridge Crystallographic Data Centre (CCDC, the world-known centre (http://www.ccdc.cam.ac.uk responsible for deposition and control of crystallographic data, including atomic coordinates that define the three-dimensional structures of organic molecules and metal complexes containing organic ligands. Cambride Structural Database (CSD, one among the first established electronic databases, nowadays is the most significant crystallographic database in the world. CSD has about 400,000 deposited structures. The use of the extensive database, which is growing rapidly, needs support of efficient and sophisticated software for searching, analysing and visualising structural data. The seminal role of CSD in the research related to crystallography, chemistry, material sciences, solid state physics and chemistry, life sciences, pharmacology, and in particular in drug design, has been documented in more than 1300 scientific papers. The important issues of CCDC are the accuracy of deposited data and development of software that enables a wide variety of applications. Such demanding project requires higly competent team of experts; thus the article brings into focus the scientific approach of the team based on the long tradition in crystallography, modelling and informatics. The article is not dedicated to 40th anniversary of the centre only, but it also reveals how Cambridge Structural Database can be used in the research and teaching. The use of electronic media and computer graphics makes “data mining" very efficient and useful but also esthetically appealing due to the molecular architecture. At the Rudjer Bošković Institute, Zagreb, Croatia there is The National Affiliated Centre of Cambridge Crystallographic Data Centre responsible for communication and dissemination of CSD in Croatia, Slovenia and Macedonia. The use of CSD is illustrated by two examples performed and published by the presenting

  18. Factors affecting reservoir and stream-water quality in the Cambridge, Massachusetts, drinking-water source area and implications for source-water protection

    Science.gov (United States)

    Waldron, Marcus C.; Bent, Gardner C.

    2001-01-01

    This report presents the results of a study conducted by the U.S. Geological Survey, in cooperation with the city of Cambridge, Massachusetts, Water Department, to assess reservoir and tributary-stream quality in the Cambridge drinking-water source area, and to use the information gained to help guide the design of a comprehensive water-quality monitoring program for the source area. Assessments of the quality and trophic state of the three primary storage reservoirs, Hobbs Brook Reservoir, Stony Brook Reservoir, and Fresh Pond, were conducted (September 1997-November 1998) to provide baseline information on the state of these resources and to determine the vulnerability of the reservoirs to increased loads of nutrients and other contaminants. The effects of land use, land cover, and other drainage-basin characteristics on sources, transport, and fate of fecal-indicator bacteria, highway deicing chemicals, nutrients, selected metals, and naturally occurring organic compounds in 11 subbasins that contribute water to the reservoirs also was investigated, and the data used to select sampling stations for incorporation into a water-quality monitoring network for the source area. All three reservoirs exhibited thermal and chemical stratification, despite artificial mixing by air hoses in Stony Brook Reservoir and Fresh Pond. The stratification produced anoxic or hypoxic conditions in the deepest parts of the reservoirs and these conditions resulted in the release of ammonia nitrogen orthophosphate phosphorus, and dissolved iron and manganese from the reservoir bed sediments. Concentrations of sodium and chloride in the reservoirs usually were higher than the amounts recommended by the U.S. Environmental Protection agency for drinking-water sources (20 milligrams per liter for sodium and 250 milligrams per liter for chloride). Maximum measured sodium concentrations were highest in Hobbs Brook Reservoir (113 milligrams per liter), intermediate in Stony Brook Reservoir (62

  19. PHP-HT (VitaResc Biotech).

    Science.gov (United States)

    Baldwin, A; Wiley, E

    2001-04-01

    VitaResc (formerly Apex) is developing PHP-HT, pyridoxalated hemoglobin polyoxyethylene conjugate, for the potential treatment of nitric oxide-induced shock (characterized by hypotension), associated with various etiologies, initially in septic shock. A phase I safety study and an initial phase I/II patient trial for NO-induced shock have been completed, and VitaResc has enrolled patients in three of five planned cohorts in a continuation of these trials to include a protocol of continuous infusion and dose escalation [330680,349187,390918]. The results from the dose escalation trials are expected to provide the basis for a randomized, controlled phase II/III pivotal trial of PHP-HT [390918]. VitaResc has licensed PHP-HT exclusively from Ajinomoto for all indications, worldwide, except Japan [275263]. Ajinomoto originally developed the human derived and chemically modified hemoglobin preparation as a blood substitute, but no development has been reported by the company since 1997 [275277,303577]. The other potential indications of PHP-HT include shock associated with burns, pancreatitis, hemodialysis and cytokine therapies [275277]. VitaResc expects the annual market potential of PHP-HT to exceed 1 billion dollars [330680].

  20. Communicating financials in the biotech industry

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte

    2008-01-01

    , Novozymes. Research indicates that besides accommodating a legal demand for the disclosure of company financial details, the annual report, in particular the letter to the shareholders or the CEO's letter, serves the purpose of marketing the company to its constituents (Bowman 1984; Bülow-Møller 2003...... discourse. In this context, the rhetorical appeals of rationality, credibility and affect play an important role. Further, the New Rhetorical focus on audience, involving the concept of ‘presence', as well Conceptual Metaphor Theory's focus on metaphor's cognitive and functional qualities yields useful...

  1. Structure, Employment and Performance in Biotech Firms

    DEFF Research Database (Denmark)

    Valentin, Finn; Dahlgren, Johan Henrich; Lund Jensen, Rasmus

    2006-01-01

    This report studies employment effects associated with the adoption of modern biotechnology in Danish industry. In this context we also examine industry structure, patterns of job creation, key outputs such as patents and the pipeline of projects in clinical trials. To see the development of Danish...... economy to perform in the transition towards knowledge and sciencebased competitiveness. That is so because DDFs to an unusual extent depend on the ability of their framework to perform as an innovation system, by which we refer to advantages growing out of interactions and complementarities between e.......g. universities, firms and venture capital. That makes DDFs a sensitive "seismograph" for the ability of the Danish innovation system to foster new science-based technologies.Key words: Employment, Biotechnology, Firm size distribution, Industry structure,Firm performanceJEL Codes: J21, L11, L22, L25, L65, O57...

  2. IDC perspectives on biotech SMME development

    CSIR Research Space (South Africa)

    Fourie, Christo

    2017-10-01

    Full Text Available This presentation discusses the focus areas of the Industrial Development Corporation (IDC), and what the IDC has achieved in terms of technology development and commercialization, especially in Biotechnology. It also focuses on future technology...

  3. agri-biotech applications' biosafety initiative

    African Journals Online (AJOL)

    these workshops are: Mexico, Costa Rica, in Mexico being the recipient, Monsanto (USA). Argentina, Uruguay, Paraguay, Brazil, technology donor, and Rockefeller Foundation. Malaysia, Thailand, the People's Republic of financial donor; (4) training of a Mexican. China, Indonesia and the Philippines. scientist in the USA in ...

  4. Biotech Information-Sharing Memorandum of Understanding

    Science.gov (United States)

    EPA, FDA, and the U.S. Department of Agriculture's Animal and Plant Health Inspection Service/Biotechnology Regulatory Services share the regulatory oversight over genetically engineered plants and the foods derived from such plants.

  5. Communicating Biotech Advances: Fiction versus Reality.

    Science.gov (United States)

    Małyska, Aleksandra; Bolla, Robert; Twardowski, Tomasz

    2018-02-01

    Bioscience novels use selected technologies of genetic engineering and synthetic biology to create entertaining stories. These novels are usually based on scientific knowledge, but they may arouse public concerns about technology and drive public reluctance to accept innovative technologies. The scientific community must adopt more efficient communication and transparency. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. The new era of biotech insulin analogues.

    Science.gov (United States)

    Brange, J

    1997-07-01

    Many of the structural properties of insulin have evolved in response to the requirements of biosynthesis, processing, transport and storage in the pancreatic beta cells, properties that are not necessary for the biological action of the hormone. It is therefore not surprising that wild-type insulin has far from optimal characteristics for replacement therapy. For example, native human insulin self-associates to hexameric units, which limits the possibilities for the absorption of the molecule by various routes. During the last decade new techniques of molecular design have emerged and recombinant DNA technology offers new and exciting opportunities for rational protein drug design. This review describes examples of recent advances in insulin engineering aimed at optimizing the hormone for therapy. Such approaches focus on improvements in the pharmacokinetic properties, storage stability, and feasibility for less intrusive routes of administration.

  7. Correlates of time spent walking and cycling to and from work: baseline results from the commuting and health in Cambridge study

    Directory of Open Access Journals (Sweden)

    Panter Jenna

    2011-11-01

    Full Text Available Abstract Purpose Environmental perceptions and psychological measures appear to be associated with walking and cycling behaviour; however, their influence is still unclear. We assessed these associations using baseline data from a quasi-experimental cohort study of the effects of major transport infrastructural developments in Cambridge, UK. Methods Postal surveys were sent to adults who travel to work in Cambridge (n = 1582. Questions asked about travel modes and time spent travelling to and from work in the last week, perceptions of the route, psychological measures regarding car use and socio-demographic characteristics. Participants were classified into one of two categories according to time spent walking for commuting ('no walking' or 'some walking' and one of three categories for cycling ('no cycling', '1-149 min/wk' and ' ≥ 150 min/wk'. Results Of the 1164 respondents (68% female, mean (SD age: 42.3 (11.4 years 30% reported any walking and 53% reported any cycling to or from work. In multiple regression models, short distance to work and not having access to a car showed strong positive associations with both walking and cycling. Furthermore, those who reported that it was pleasant to walk were more likely to walk to or from work (OR = 4.18, 95% CI 3.02 to 5.78 and those who reported that it was convenient to cycle on the route between home and work were more likely to do so (1-149 min/wk: OR = 4.60, 95% CI 2.88 to 7.34; ≥ 150 min/wk: OR = 3.14, 95% CI 2.11 to 4.66. Positive attitudes in favour of car use were positively associated with time spent walking to or from work but negatively associated with cycling to or from work. Strong perceived behavioural control for car use was negatively associated with walking. Conclusions In this relatively affluent sample of commuters, a range of individual and household characteristics, perceptions of the route environment and psychological measures relating to car use were associated with

  8. “In my end is my beginning”. Una discussione sul caso trascurato dei Cambridge Ritualists fra antropologia comparativa, filosofia e pensiero scientifico - “In my end is my beginning”. An argument on the Cambridge Ritualists’ neglected case, on the wave of comparative anthropology, philosophy and scientific thought

    Directory of Open Access Journals (Sweden)

    Danila Cinellu

    2015-12-01

    Full Text Available Somehow rounding off an intellectual season in which humanities strongly lament the loss of Darwinian incitements, while exploiting both Wilson’s biophilia hypothesis and Rappaport’s engaged anthropology as springboards, this article wants to cast light on how two anthropologically undervalued manifestos of the Cambridge School – Harrison’s Themis (1912 and Cornford’s From Religion to Philosophy (1912 – laid the foundation of post-modern science. It highlights, in other words, how within evolutionary anthropology, to which we owe the birth of the comparative study of religions, were surreptitiously raised significant issues against eco-systemic disfunctionalities due to the scientific pattern rooted in Atomism and modern Cartesianism itself. In order to counteract the conventional belief that evolutionary anthropology was entirely shaped by the kind of Positivism of Illuministic inspiration, the association between the “mystic” and the “savage” will be once more taken into consideration. In this regard, a quite unreleased focus on Lévi-Strauss’ paradigm “le totémism du dedans” is deemed also essential. As a consequence, the unfairly forgotten Cambridge Ritualists, Harrison and Cornford, will be especially rehearsed in the light of their adoption of the philosophical Bergsonian concept of durée as a means of probing into the monist vision enshrined in the mysteric religion of Ancient Greece. It is basically the special attention allotted to the mystic’s incorporation of a limitless cyclic time which helps us to detect the extent to which both Harrison and Cornford aimed at propounding an ethical anthropology eager to denounce the forward end because of the obdurate human projection outside the sphere of Life itself. What this essay thus propounds is not a rehearsal of the Cambridge School for the sake of it. While advocating cumulative knowledge around the very same foundation of the “scientific study of

  9. An investigation into the impact of question structure on the performance of first year physics undergraduate students at the University of Cambridge

    Science.gov (United States)

    Gibson, Valerie; Jardine-Wright, Lisa; Bateman, Elizabeth

    2015-07-01

    We describe a study of the impact of exam question structure on the performance of first year Natural Sciences physics undergraduates from the University of Cambridge. The results show conclusively that a student’s performance improves when questions are scaffolded compared with university style questions. In a group of 77 female students we observe that the average exam mark increases by 13.4% for scaffolded questions, which corresponds to a 4.9 standard deviation effect. The equivalent observation for 236 male students is 9% (5.5 standard deviations). We also observe a correlation between exam performance and A2-level marks for UK students, and that students who receive their school education overseas, in a mixed gender environment, or at an independent school are more likely to receive a first class mark in the exam. These results suggest a mis-match between the problem-solving skills and assessment procedures between school and first year university and will provide key input into the future teaching and assessment of first year undergraduate physics students.

  10. The Cambridge Prognostic Groups for improved prediction of disease mortality at diagnosis in primary non-metastatic prostate cancer: a validation study.

    Science.gov (United States)

    Gnanapragasam, V J; Bratt, O; Muir, K; Lee, L S; Huang, H H; Stattin, P; Lophatananon, A

    2018-02-28

    The purpose of this study is to validate a new five-tiered prognostic classification system to better discriminate cancer-specific mortality in men diagnosed with primary non-metastatic prostate cancer. We applied a recently described five-strata model, the Cambridge Prognostic Groups (CPGs 1-5), in two international cohorts and tested prognostic performance against the current standard three-strata classification of low-, intermediate- or high-risk disease. Diagnostic clinico-pathological data for men obtained from the Prostate Cancer data Base Sweden (PCBaSe) and the Singapore Health Study were used. The main outcome measure was prostate cancer mortality (PCM) stratified by age group and treatment modality. The PCBaSe cohort included 72,337 men, of whom 7162 died of prostate cancer. The CPG model successfully classified men with different risks of PCM with competing risk regression confirming significant intergroup distinction (p study of nearly 75,000 men confirms that the CPG five-tiered prognostic model has superior discrimination compared to the three-tiered model in predicting prostate cancer death across different age and treatment groups. Crucially, it identifies distinct sub-groups of men within the old intermediate-risk and high-risk criteria who have very different prognostic outcomes. We therefore propose adoption of the CPG model as a simple-to-use but more accurate prognostic stratification tool to help guide management for men with newly diagnosed prostate cancer.

  11. Italian normative data and validation of two neuropsychological tests of face recognition: Benton Facial Recognition Test and Cambridge Face Memory Test.

    Science.gov (United States)

    Albonico, Andrea; Malaspina, Manuela; Daini, Roberta

    2017-09-01

    The Benton Facial Recognition Test (BFRT) and Cambridge Face Memory Test (CFMT) are two of the most common tests used to assess face discrimination and recognition abilities and to identify individuals with prosopagnosia. However, recent studies highlighted that participant-stimulus match ethnicity, as much as gender, has to be taken into account in interpreting results from these tests. Here, in order to obtain more appropriate normative data for an Italian sample, the CFMT and BFRT were administered to a large cohort of young adults. We found that scores from the BFRT are not affected by participants' gender and are only slightly affected by participant-stimulus ethnicity match, whereas both these factors seem to influence the scores of the CFMT. Moreover, the inclusion of a sample of individuals with suspected face recognition impairment allowed us to show that the use of more appropriate normative data can increase the BFRT efficacy in identifying individuals with face discrimination impairments; by contrast, the efficacy of the CFMT in classifying individuals with a face recognition deficit was confirmed. Finally, our data show that the lack of inversion effect (the difference between the total score of the upright and inverted versions of the CFMT) could be used as further index to assess congenital prosopagnosia. Overall, our results confirm the importance of having norms derived from controls with a similar experience of faces as the "potential" prosopagnosic individuals when assessing face recognition abilities.

  12. Face ethnicity and measurement reliability affect face recognition performance in developmental prosopagnosia: evidence from the Cambridge Face Memory Test-Australian.

    Science.gov (United States)

    McKone, Elinor; Hall, Ashleigh; Pidcock, Madeleine; Palermo, Romina; Wilkinson, Ross B; Rivolta, Davide; Yovel, Galit; Davis, Joshua M; O'Connor, Kirsty B

    2011-03-01

    The Cambridge Face Memory Test (CFMT, Duchaine & Nakayama, 2006) provides a validated format for testing novel face learning and has been a crucial instrument in the diagnosis of developmental prosopagnosia. Yet, some individuals who report everyday face recognition symptoms consistent with prosopagnosia, and are impaired on famous face tasks, perform normally on the CFMT. Possible reasons include measurement error, CFMT assessment of memory only at short delays, and a face set whose ethnicity is matched to only some Caucasian groups. We develop the "CFMT-Australian" (CFMT-Aus), which complements the CFMT-original by using ethnicity better matched to a different European subpopulation. Results confirm reliability (.88) and validity (convergent, divergent using cars, inversion effects). We show that face ethnicity within a race has subtle but clear effects on face processing even in normal participants (includes cross-over interaction for face ethnicity by perceiver country of origin in distinctiveness ratings). We show that CFMT-Aus clarifies diagnosis of prosopagnosia in 6 previously ambiguous cases. In 3 cases, this appears due to the better ethnic match to prosopagnosics. We also show that face memory at short (<3-min), 20-min, and 24-hr delays taps overlapping processes in normal participants. There is some suggestion that a form of prosopagnosia may exist that is long delay only and/or reflects failure to benefit from face repetition. © 2011 Psychology Press, an imprint of the Taylor & Francis Group, an Informa business

  13. Decision-making deficits in patients diagnosed with disordered gambling using the Cambridge Gambling task: the effects of substance use disorder comorbidity.

    Science.gov (United States)

    Zois, Evangelos; Kortlang, Noreen; Vollstädt-Klein, Sabine; Lemenager, Tagrid; Beutel, Martin; Mann, Karl; Fauth-Bühler, Mira

    2014-07-01

    Disordered gambling (DG) has often been associated with impaired decision-making abilities, suggesting a dysfunction in the ventromedial prefrontal cortex (vmPFC). To our knowledge, no previous study has accurately considered the effect of substance use disorder (SUD) comorbidity (including nicotine dependence) on decision-making impairments in DG. We employed the Cambridge Gambling Task (CGT) to assess a big cohort of patients diagnosed with DG (N = 80) against matched healthy controls (HCs) (N = 108). The cohort included DG patients with nicotine and alcohol dependence, alcohol dependence only and 12 "pure" nonsmokers with only DG diagnosis. Pure nonsmoking, nicotine dependent as well as alcoholic DGs with current nicotine dependence, demonstrated a decision making profile, characterized by poor decision-making abilities and failure to make right choices (rational), closely resembling that of patients with vmPFC damage. This suggests that DGs with and without SUD comorbidity are equally affected in that domain of decision making abilities. Additionally, gambling diagnosis combined with alcohol and nicotine dependence involves a group of gambling patients with a relatively riskier decision making profile, showing that these patients apart from making irrational decisions take also more risks. Our findings highlight the importance of accounting for SUD comorbidities with useful implications for future research and therapy. Limitations of the current investigation are discussed.

  14. Construct and concurrent validity of the Cambridge neuropsychological automated tests in Portuguese older adults without neuropsychiatric diagnoses and with Alzheimer's disease dementia.

    Science.gov (United States)

    Matos Gonçalves, Marta; Pinho, Maria Salomé; Simões, Mário R

    2018-03-01

    We aimed to analyze the construct and concurrent validity of the Rapid Visual Information Processing (RVP), Paired Associates Learning (PAL), Reaction Time (RTI), and Spatial Working Memory (SWM) tests from the Cambridge Neuropsychological Test Automated Battery (CANTAB®). Inclusion criteria were checked in a first session. The CANTAB and additional pencil-and-paper tests were administered within 1 week. The participants (aged 69-96 years) were 137 Portuguese adults without neuropsychiatric diagnoses and 37 adults with mild-to-moderate Alzheimer's disease dementia. Comparisons were made between the CANTAB tests and between these tests and the Rey Complex Figure Test (RCFT), Verbal Fluency (VF) test, and some Wechsler Memory Scale-III and Wechsler Adult Intelligence Scale-III subtests. Most intra-test correlations were stronger than the CANTAB inter-test correlations. The RVP correlated more with VF animals (.44), the PAL with RCFT immediate recall (-.52), the RTI with RVP mean latency (.42), and the SWM with Spatial Span backward (-.39).

  15. The Cambridge Companion to Dewey. Cambridge Companions to Philosophy

    Science.gov (United States)

    Cochran, Molly

    2010-01-01

    John Dewey (1859-1952) was a major figure of the American cultural and intellectual landscape in the first half of the twentieth century. While not the originator of American pragmatism, he was instrumental to its articulation as a philosophy and the spread of its influence beyond philosophy to other disciplines. His prolific writings encompass…

  16. Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the Calgary-Cambridge Guide to the Medical Interview.

    Science.gov (United States)

    Burt, Jenni; Abel, Gary; Elmore, Natasha; Campbell, John; Roland, Martin; Benson, John; Silverman, Jonathan

    2014-03-06

    To investigate initial reliability of the Global Consultation Rating Scale (GCRS: an instrument to assess the effectiveness of communication across an entire doctor-patient consultation, based on the Calgary-Cambridge guide to the medical interview), in simulated patient consultations. Multiple ratings of simulated general practitioner (GP)-patient consultations by trained GP evaluators. UK primary care. 21 GPs and six trained GP evaluators. GCRS score. 6 GP raters used GCRS to rate randomly assigned video recordings of GP consultations with simulated patients. Each of the 42 consultations was rated separately by four raters. We considered whether a fixed difference between scores had the same meaning at all levels of performance. We then examined the reliability of GCRS using mixed linear regression models. We augmented our regression model to also examine whether there were systematic biases between the scores given by different raters and to look for possible order effects. Assessing the communication quality of individual consultations, GCRS achieved a reliability of 0.73 (95% CI 0.44 to 0.79) for two raters, 0.80 (0.54 to 0.85) for three and 0.85 (0.61 to 0.88) for four. We found an average difference of 1.65 (on a 0-10 scale) in the scores given by the least and most generous raters: adjusting for this evaluator bias increased reliability to 0.78 (0.53 to 0.83) for two raters; 0.85 (0.63 to 0.88) for three and 0.88 (0.69 to 0.91) for four. There were considerable order effects, with later consultations (after 15-20 ratings) receiving, on average, scores more than one point higher on a 0-10 scale. GCRS shows good reliability with three raters assessing each consultation. We are currently developing the scale further by assessing a large sample of real-world consultations.

  17. Specific Features of Executive Dysfunction in Alzheimer-Type Mild Dementia Based on Computerized Cambridge Neuropsychological Test Automated Battery (CANTAB) Test Results.

    Science.gov (United States)

    Kuzmickienė, Jurgita; Kaubrys, Gintaras

    2016-10-08

    BACKGROUND The primary manifestation of Alzheimer's disease (AD) is decline in memory. Dysexecutive symptoms have tremendous impact on functional activities and quality of life. Data regarding frontal-executive dysfunction in mild AD are controversial. The aim of this study was to assess the presence and specific features of executive dysfunction in mild AD based on Cambridge Neuropsychological Test Automated Battery (CANTAB) results. MATERIAL AND METHODS Fifty newly diagnosed, treatment-naïve, mild, late-onset AD patients (MMSE ≥20, AD group) and 25 control subjects (CG group) were recruited in this prospective, cross-sectional study. The CANTAB tests CRT, SOC, PAL, SWM were used for in-depth cognitive assessment. Comparisons were performed using the t test or Mann-Whitney U test, as appropriate. Correlations were evaluated by Pearson r or Spearman R. Statistical significance was set at p<0.05. RESULTS AD and CG groups did not differ according to age, education, gender, or depression. Few differences were found between groups in the SOC test for performance measures: Mean moves (minimum 3 moves): AD (Rank Sum=2227), CG (Rank Sum=623), p<0.001. However, all SOC test time measures differed significantly between groups: SOC Mean subsequent thinking time (4 moves): AD (Rank Sum=2406), CG (Rank Sum=444), p<0.001. Correlations were weak between executive function (SOC) and episodic/working memory (PAL, SWM) (R=0.01-0.38) or attention/psychomotor speed (CRT) (R=0.02-0.37). CONCLUSIONS Frontal-executive functions are impaired in mild AD patients. Executive dysfunction is highly prominent in time measures, but minimal in performance measures. Executive disorders do not correlate with a decline in episodic and working memory or psychomotor speed in mild AD.

  18. Changes in diet, cardiovascular risk factors and modelled cardiovascular risk following diagnosis of diabetes: 1-year results from the ADDITION-Cambridge trial cohort.

    Science.gov (United States)

    Savory, L A; Griffin, S J; Williams, K M; Prevost, A T; Kinmonth, A-L; Wareham, N J; Simmons, R K

    2014-02-01

    To describe change in self-reported diet and plasma vitamin C, and to examine associations between change in diet and cardiovascular disease risk factors and modelled 10-year cardiovascular disease risk in the year following diagnosis of Type 2 diabetes. Eight hundred and sixty-seven individuals with screen-detected diabetes underwent assessment of self-reported diet, plasma vitamin C, cardiovascular disease risk factors and modelled cardiovascular disease risk at baseline and 1 year (n = 736) in the ADDITION-Cambridge trial. Multivariable linear regression was used to quantify the association between change in diet and cardiovascular disease risk at 1 year, adjusting for change in physical activity and cardio-protective medication. Participants reported significant reductions in energy, fat and sodium intake, and increases in fruit, vegetable and fibre intake over 1 year. The reduction in energy was equivalent to an average-sized chocolate bar; the increase in fruit was equal to one plum per day. There was a small increase in plasma vitamin C levels. Increases in fruit intake and plasma vitamin C were associated with small reductions in anthropometric and metabolic risk factors. Increased vegetable intake was associated with an increase in BMI and waist circumference. Reductions in fat, energy and sodium intake were associated with reduction in HbA1c , waist circumference and total cholesterol/modelled cardiovascular disease risk, respectively. Improvements in dietary behaviour in this screen-detected population were associated with small reductions in cardiovascular disease risk, independently of change in cardio-protective medication and physical activity. Dietary change may have a role to play in the reduction of cardiovascular disease risk following diagnosis of diabetes. © 2013 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.

  19. The Cambridge companion to Galileo

    CERN Document Server

    1998-01-01

    This collection of essays is unparalleled in the depth of its coverage of all facets of Galileo's work. A particular feature of the volume is the treatment of Galileo's relationship with the Church. It will be of particular interest to philosophers, historians of science, cultural historians and those in religious studies. New readers and nonspecialists will find this the most convenient, accessible guide to Galileo available. Advanced students and specialists will find a conspectus of recent developments in the interpretation of Galileo.

  20. Why raspberries flourish in Cambridge

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Royer, Susanne; Brown, Kerry

    The activities and role of entrepreneurial milieu in fostering novel products are examined in this research. Creative ideas that initiate disjuncture from prevailing paradigms and form from the aggregation of individuals and concentrated efforts coalescing around a common problem are the subject...

  1. RFID solution benefits Cambridge hospital.

    Science.gov (United States)

    James, Andrew

    2013-10-01

    Keeping track of thousands of pieces of equipment in a busy hospital environment is a considerable challenge, but, according to RFID tagging and asset tracking specialist, Harland Simon, RFID technology can make the task considerably simpler. Here Andrew James, the company's RFID sales manager, describes the positive benefits the technology has brought the Medical Equipment Library (MEL) at Addenbrooke's Hospital, one of the world's most famous teaching hospitals.

  2. Sea Consultants Inc, Cambridge, MA

    International Nuclear Information System (INIS)

    Reed, D.F.

    1989-01-01

    The EPA is currently developing regulations to limit the radon concentration in public water supplies. Based on the latest scientific evaluations, it appears that the health impact of radon is larger than suggested by guidelines used at the state level. The radon maximum contaminant level being discussed would impact over half of the groundwater supplies in the country and a larger percentage in the New England States. In Friendship, Maine, a public water system was recently placed into operation that uses a bedrock well as a source. High radon levels are treated using granulated activated carbon contactors. Performance testing was completed that provides insight into process effectiveness and the flexibility of GAC to respond to varying loading rates. 17 refs., 5 figs., 1 tab

  3. Falls in advanced old age: recalled falls and prospective follow-up of over-90-year-olds in the Cambridge City over-75s Cohort study

    Directory of Open Access Journals (Sweden)

    Matthews Fiona E

    2008-03-01

    Full Text Available Abstract Background The "oldest old" are now the fastest growing section of most western populations, yet there are scarcely any data concerning even the common problem of falls amongst the very old. Prospective data collection is encouraged as the most reliable method for researching older people's falls, though in clinical practice guidelines advise taking a history of any recalled falls. This study set out to inform service planning by describing the epidemiology of falls in advanced old age using both retrospectively and prospectively collected falls data. Methods Design: Re-survey of over-90-year-olds in a longitudinal cohort study – cross-sectional interview and intensive 12-month follow-up. Participants and setting: 90 women and 20 men participating in a population-based cohort (aged 91–105 years, in care-homes and community-dwelling recruited from representative general practices in Cambridge, UK Measurements: Prospective falls data were collected using fall calendars and telephone follow-up for one year after cross-sectional survey including fall history. Results 58% were reported to have fallen at least once in the previous year and 60% in the 1-year follow-up. The proportion reported to have fallen more than once was lower using retrospective recall of the past year than prospective reports gathered the following year (34% versus 45%, as were fall rates (1.6 and 2.8 falls/person-year respectively. Repeated falls in the past year were more highly predictive of falls during the following year – IRR 4.7, 95% CI 2.6–8.7 – than just one – IRR 3.6, 95% CI 2.0–6.3, using negative binomial regression. Only 1/5 reportedly did not fall during either the year before or after interview. Conclusion Fall rates in this representative sample of over-90-year-olds are even higher than previous reports from octogenarians. Recalled falls last year, particularly repeated falls, strongly predicted falls during follow-up. Similar proportions

  4. Assessing communication quality of consultations in primary care: initial reliability of the Global Consultation Rating Scale, based on the Calgary-Cambridge Guide to the Medical Interview

    Science.gov (United States)

    Burt, Jenni; Abel, Gary; Elmore, Natasha; Campbell, John; Roland, Martin; Benson, John; Silverman, Jonathan

    2014-01-01

    Objectives To investigate initial reliability of the Global Consultation Rating Scale (GCRS: an instrument to assess the effectiveness of communication across an entire doctor–patient consultation, based on the Calgary-Cambridge guide to the medical interview), in simulated patient consultations. Design Multiple ratings of simulated general practitioner (GP)–patient consultations by trained GP evaluators. Setting UK primary care. Participants 21 GPs and six trained GP evaluators. Outcome measures GCRS score. Methods 6 GP raters used GCRS to rate randomly assigned video recordings of GP consultations with simulated patients. Each of the 42 consultations was rated separately by four raters. We considered whether a fixed difference between scores had the same meaning at all levels of performance. We then examined the reliability of GCRS using mixed linear regression models. We augmented our regression model to also examine whether there were systematic biases between the scores given by different raters and to look for possible order effects. Results Assessing the communication quality of individual consultations, GCRS achieved a reliability of 0.73 (95% CI 0.44 to 0.79) for two raters, 0.80 (0.54 to 0.85) for three and 0.85 (0.61 to 0.88) for four. We found an average difference of 1.65 (on a 0–10 scale) in the scores given by the least and most generous raters: adjusting for this evaluator bias increased reliability to 0.78 (0.53 to 0.83) for two raters; 0.85 (0.63 to 0.88) for three and 0.88 (0.69 to 0.91) for four. There were considerable order effects, with later consultations (after 15–20 ratings) receiving, on average, scores more than one point higher on a 0–10 scale. Conclusions GCRS shows good reliability with three raters assessing each consultation. We are currently developing the scale further by assessing a large sample of real-world consultations. PMID:24604483

  5. On the type species of the genus Aetius O. Pickard-Cambridge, 1896: The first description of male with notes on cymbial notch and mating plug (Araneae: Corinnidae: Castianeirinae).

    Science.gov (United States)

    Sudhin, Puthoor Pattammal; Nafin, Karunnappilli Shamsudheen; Simmons, Zoë; Sudhikumar, Ambalaparambil Vasu

    2016-08-23

    The rare ant mimicking sac spider genus Aetius was erected by O. Pickard-Cambridge in 1896 based on an unspecified number of female specimen(s) collected from Sri Lanka. The type species of the genus, A. decollatus O. Pickard-Cambridge, 1896, has been redescribed twice based on the holotype (Majumder & Tikader 1991; Deeleman-Reinhold 2001). Reimoser (1934) recorded the genus for the first time from India, who collected a male specimen from Mudumalai Tiger Reserve in Tamil Nadu State of southern India. This specimen was identified as A. decollatus, but it was never formally described and was later recognised to be a penultimate male (Dankittipakul & Singtripop 2013). Deeleman-Reinhold (2001) described the second representative of the genus, A. nocturnus, based on a single female specimen from Borneo, 105 years after the establishment of the genus. Dankittipakul & Singtripop (2013) described the male of A. nocturnus, thereby revealing the male genitalia of the genus, but the type species was still known only from the female sex.

  6. 17 January 2011 - British (Cambridge) Trustee of the London Science Museum Chair of the Management Committee of the Newton Institute for Mathematical Sciences H. Covington in the LHCB underground experimental area with A. Schopper; signing the guest book with Director for Accelerators and Technology S. Myers; throughout accompanied by R. Veness.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    17 January 2011 - British (Cambridge) Trustee of the London Science Museum Chair of the Management Committee of the Newton Institute for Mathematical Sciences H. Covington in the LHCB underground experimental area with A. Schopper; signing the guest book with Director for Accelerators and Technology S. Myers; throughout accompanied by R. Veness.

  7. Can they recover? An assessment of adult adjustment problems among males in the abstainer, recovery, life-course persistent, and adolescence-limited pathways followed up to age 56 in the Cambridge Study in Delinquent Development.

    Science.gov (United States)

    Jennings, Wesley G; Rocque, Michael; Fox, Bryanna Hahn; Piquero, Alex R; Farrington, David P

    2016-05-01

    Much research has examined Moffitt's developmental taxonomy, focusing almost exclusively on the distinction between life-course persistent and adolescence-limited offenders. Of interest, a handful of studies have identified a group of individuals whose early childhood years were marked by extensive antisocial behavior but who seemed to recover and desist (at least from severe offending) in adolescence and early adulthood. We use data from the Cambridge Study in Delinquent Development to examine the adult adjustment outcomes of different groups of offenders, including a recoveries group, in late middle adulthood, offering the most comprehensive investigation of this particular group to date. Findings indicate that abstainers comprise the largest group of males followed by adolescence-limited offenders, recoveries, and life-course persistent offenders. Furthermore, the results reveal that a host of adult adjustment problems measured at ages 32 and 48 in a number of life-course domains are differentially distributed across these four offender groups. In addition, the recoveries and life-course persistent offenders often show the greatest number of adult adjustment problems relative to the adolescence-limited offenders and abstainers.

  8. Outlook: directed development: catalysing a global biotech industry.

    Science.gov (United States)

    Sun, Anthony; Perkins, Tom

    2005-09-01

    Governments are increasingly relying on directed development tools or proactive public-policy approaches to stimulate scientific and economic development for their biotechnology industries. This article will discuss the four main tools of directed development in biotechnology and the lessons learned from current global efforts utilizing these tools.

  9. Careers at Biotech Start-Ups and in Entrepreneurship.

    Science.gov (United States)

    Froshauer, Susan

    2017-11-01

    The world of biotechnology "start-ups" and entrepreneurship offers exciting new avenues for driving state-of-the-art research using an arsenal of multidisciplinary skills, whether your role is as part of a team or as a leader. Although traditionally these positions may not be as secure as those offered by some of the larger companies, the small start-up culture provides opportunities for contributing at many levels to a wide range of responsibilities: from scientific discovery to delivery of proof of concept and intellectual property; from analysis of market opportunities and competitive intelligence to creation of time lines and business plans for a first product. Often, if you get in on the ground level, you get to validate your own concept, pitch to potential investors, argue value, build a team, engage advisors, and then, with funding in hand, launch an entirely new research and development (R&D) enterprise. Many of the skills and much of the experience gained while pursuing a graduate degree can be put to good use in these arenas as well. This path, however, is not for the faint of heart; it requires not only a strong scientific background and organizational skills, but also the ability to work well on a team, excellent communication skills, and persistence when faced with delays or disappointment. With increasing responsibilities in the small company come the requirements for aptitudes for leadership, strategic and financial planning, networking, negotiating, and managing both projects and personnel. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.

  10. Licensing biotech intellectual property in university-industry partnerships.

    Science.gov (United States)

    Drozdoff, Vladimir; Fairbairn, Daryl

    2015-01-20

    Appropriate negotiation and drafting of license agreements are critical to successfully establishing and managing the expansive and complex relationships that are becoming more common between industry and universities. More often than not, the resulting licensing agreements become quite lengthy and complex, and the key principles become difficult to discern among all the details. This summary provides a short, nonexhaustive introduction to some of the essential components of these licenses with the intent of providing the non-licensing professional a better appreciation of some of the key commercial and legal terms from both an academic and company perspective, keeping in mind some of the considerations that particularly apply to biotechnology deals. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

  11. THE ROLE OF BIOTECH:'\\OLOGY IN CROP IMPROVEMENT ...

    African Journals Online (AJOL)

    BSN

    The isolation of cell or protoplast. culture media and regeneration of plants under each kind ... with 3% sucrose and agar was used to germinate embryos of several .'vfc111ihot .... Should invest in m J.:m b "':echnology research in agriculture such ... R ibon~1cle1c acid-Aids in protein synthesis of transrer and mcssen;cr Ri\\.

  12. Nig J. Biotech. Vol. 21 (2010) 35 – 40

    African Journals Online (AJOL)

    BSN

    Available online at ... and the beverage has been drunk there for the past 2000 – 3000 ... market is embracing other types of tea that are made ... The mineral contents of the .... after the birth of a child (Swerdlow, 2000). ... In: Analysis of Foods.

  13. Establishing a biotech-modern-agriculture for China | Zhengbin ...

    African Journals Online (AJOL)

    China, with a large population and small amount of arable land, is a populous as well as a large agricultural country. In order to ensure food security, agricultural sustainable development and prosperity of agriculture economy, modern agriculture based on biotechnology combined with modern equipment must be ...

  14. Evaluation and Audience Acceptance in Biotech News Texts

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte; Vestergaard, Torben

    2009-01-01

    It is well known that news texts are not value neutral and that in these texts even genuinely factual statements can function as evaluations. Hence, only an analysis of the types of evaluation used will reveal the true picture of the attitudinal import of reporting texts. The paper explores...... these features by analysing the coverage of the biotechnology debate in one of the largest Danish newspapers, Politiken, during the first 9 months of 2004. The aim of this analysis is to uncover how seemingly objective and ‘neutral' accounts of events and state of affairs can be used by journalists...

  15. Frugal Biotech Applications of Low-Temperature Plasma.

    Science.gov (United States)

    Machala, Zdenko; Graves, David B

    2017-09-01

    Gas discharge low-temperature air plasma can be utilized for a variety of applications, including biomedical, at low cost. We term these applications 'frugal plasma' - an example of frugal innovation. We demonstrate how simple, robust, low-cost frugal plasma devices can be used to safely disinfect instruments, surfaces, and water. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Cleanroom energy benchmarking in high-tech and biotech industries

    International Nuclear Information System (INIS)

    Tschudi, William; Benschine, Kathleen; Fok, Stephen; Rumsey, Peter

    2001-01-01

    Cleanrooms, critical to a wide range of industries, universities, and government facilities, are extremely energy intensive. Consequently, energy represents a significant operating cost for these facilities. Improving energy efficiency in cleanrooms will yield dramatic productivity improvement. But more importantly to the industries which rely on cleanrooms, base load reduction will also improve reliability. The number of cleanrooms in the US is growing and the cleanroom environmental systems' energy use is increasing due to increases in total square footage and trends toward more energy intensive, higher cleanliness applications. In California, many industries important to the State's economy utilize cleanrooms. In California these industries utilize over 150 cleanrooms with a total of 4.2 million sq. ft. (McIlvaine). Energy intensive high tech buildings offer an attractive incentive for large base load energy reduction. Opportunities for energy efficiency improvement exist in virtually all operating cleanrooms as well as in new designs. To understand the opportunities and their potential impact, Pacific Gas and Electric Company sponsored a project to benchmark energy use in cleanrooms in the electronics (high-tech) and biotechnology industries. Both of these industries are heavily dependent intensive cleanroom environments for research and manufacturing. In California these two industries account for approximately 3.6 million sq. ft. of cleanroom (McIlvaine, 1996) and 4349 GWh/yr. (Sartor et al. 1999). Little comparative energy information on cleanroom environmental systems was previously available. Benchmarking energy use allows direct comparisons leading to identification of best practices, efficiency innovations, and highlighting previously masked design or operational problems

  17. Biotechnology regulation: limiting or contributing to biotech development?

    DEFF Research Database (Denmark)

    Hansen, Anne Grethe

    2001-01-01

    to the European arena, their role and extension are still an issue. In this paper, the often anticipated innovation-inhibiting effects of regulation are questioned by giving an account of regulations and debates in Denmark. An account which includes the shifting positions of industry, the research community......Modern biotechnology has been characterized by being surrounded by scientific and public debate and by interest conflicts. An early Danish debate and regulation has been criticized for inhibiting or retarding development and thus growth. Though much regulation and debate have been transferred...

  18. What Hold us Together? Analyzing Biotech Field Formation

    Directory of Open Access Journals (Sweden)

    Jackeline Amantino de Andrade

    2011-03-01

    Full Text Available This article proposes to analyze the formation of biotechnological field bringing actor-network theory’s lens as contribution. Based on conclusions of studies developed by Walter Powell and colleagues it was held a research to analyze the diversity of institutional relations that are active by hemophilia therapies, the principle of generalized symmetry adopted for actor-network theory is highlight to identify how socio-technical associations are assembled. Besides the interorganizational relations, research’s findings indicate the scientific and technological contents have a significant mediating role to create and sustain those connections of knowledge. So, it is emphasized the need of a boarder theoretical discussion to enlarge explanations about the dynamics of organizational fields as well as innovation processes.

  19. A Lagrangian model of air-mass photochemistry and mixing using a trajectory ensemble: the Cambridge Tropospheric Trajectory model of Chemistry And Transport (CiTTyCAT version 4.2

    Directory of Open Access Journals (Sweden)

    T. A. M. Pugh

    2012-01-01

    Full Text Available A Lagrangian model of photochemistry and mixing is described (CiTTyCAT, stemming from the Cambridge Tropospheric Trajectory model of Chemistry And Transport, which is suitable for transport and chemistry studies throughout the troposphere. Over the last five years, the model has been developed in parallel at several different institutions and here those developments have been incorporated into one "community" model and documented for the first time. The key photochemical developments include a new scheme for biogenic volatile organic compounds and updated emissions schemes. The key physical development is to evolve composition following an ensemble of trajectories within neighbouring air-masses, including a simple scheme for mixing between them via an evolving "background profile", both within the boundary layer and free troposphere. The model runs along trajectories pre-calculated using winds and temperature from meteorological analyses. In addition, boundary layer height and precipitation rates, output from the analysis model, are interpolated to trajectory points and used as inputs to the mixing and wet deposition schemes. The model is most suitable in regimes when the effects of small-scale turbulent mixing are slow relative to advection by the resolved winds so that coherent air-masses form with distinct composition and strong gradients between them. Such air-masses can persist for many days while stretching, folding and thinning. Lagrangian models offer a useful framework for picking apart the processes of air-mass evolution over inter-continental distances, without being hindered by the numerical diffusion inherent to global Eulerian models. The model, including different box and trajectory modes, is described and some output for each of the modes is presented for evaluation. The model is available for download from a Subversion-controlled repository by contacting the corresponding authors.

  20. The Cambridge Otology Quality of Life Questionnaire: an otology-specific patient-recorded outcome measure. A paper describing the instrument design and a report of preliminary reliability and validity.

    Science.gov (United States)

    Martin, T P C; Moualed, D; Paul, A; Ronan, N; Tysome, J R; Donnelly, N P; Cook, R; Axon, P R

    2015-04-01

    The Cambridge Otology Quality of Life Questionnaire (COQOL) is a patient-recorded outcome measurement (PROM) designed to quantify the quality of life of patients attending otology clinics. Item-reduction model. A systematically designed long-form version (74 items) was tested with patient focus groups before being presented to adult otology patients (n. 137). Preliminary item analysis tested reliability, reducing the COQOL to 24 questions. This was then presented in conjunction with the SF-36 (V1) questionnaire to a total of 203 patients. Subsequently, these were re-presented at T + 3 months, and patients recorded whether they felt their condition had improved, deteriorated or remained the same. Non-responders were contacted by post. A correlation between COQOL scores and patient perception of change was examined to analyse content validity. Teaching hospital and university psychology department. Adult patients attending otology clinics with a wide range of otological conditions. Item reliability measured by item–total correlation, internal consistency and test– retest reliability. Validity measured by correlation between COQOL scores and patient-reported symptom change. Reliability: the COQOL showed excellent internal consistency at both initial presentation (a = 0.90) and 3 months later (a = 0.93). Validity: One-way analysis of variance showed a significant difference between groups reporting change and those reporting no change in quality of life (F(2, 80) = 5.866, P < 0.01). The COQOL is the first otology-specific PROM. Initial studies demonstrate excellent reliability and encouraging preliminary criterion validity: further studies will allow a deeper validation of the instrument.

  1. The Cambridge encyclopedia of space (revised edition)

    Science.gov (United States)

    D'Allest, Frederic; Arets, Jean; Baker, Phillip J.; Balmino, Georges; Barth, Hans; Benson, Robert H.

    1990-01-01

    A comprehensive and intensively illustrated development history is presented for spaceflight, ranging over its basic concepts' speculative and fictional origins, the historical roots of rocket-related technologies, and the scientific accomplishments of earth orbit and interplanetary missions to date. Attention is given to propulsion systems, spaceflight launch centers, satellite systems, and solar system exploration by the U.S. and the Soviet Union. Current space-related activities encompass the meteorology, remote sensing, telecommunications and direct broadcasting, and navigation functions of unmanned satellites, as well as such manned spacecraft roles as medical and materials science research. The military uses of space, and increasingly important space industrialization concepts, are discussed as well.

  2. The Cambridge Companion to International Law

    Directory of Open Access Journals (Sweden)

    Achmad Gusman Siswandi

    2014-08-01

    Full Text Available ABSTRAK This book provides a thorough introduction to international law in a way that is rather unique compared to similar references. The subject matteris divided in a more concise way, while still giving rich perspective as it covers not only theories but also case studies and practices. This book consists of four parts, namely: the contexts of international law; international law and the state; techniques and arenas; and projects of international law.

  3. Copy-Editing: The Cambridge Handbook.

    Science.gov (United States)

    Butcher, Judith

    This handbook is designed as a reference manual for copy editors who prepare typescript for printing. It deals with the following topics: the copy editor's function; the work to be done at each stage in the production process; some difficult points of spelling, capitalization, and other features collectively known as "house style"; the parts of a…

  4. The Cambridge guide to the solar system

    National Research Council Canada - National Science Library

    Lang, Kenneth R

    2011-01-01

    ...; the encounter with asteroid Itokawa; and an encounter and sample return from comet Wild 2. The book is further enhanced by hundreds of striking new images of the planets and moons. Written at an introductory level appropriate for high-school and undergraduate students, it provides fresh insights that appeal to anyone with an interest in planetar...

  5. Quantum Gravity (Cambridge Monographs on Mathematical Physics)

    International Nuclear Information System (INIS)

    Kiefer, C

    2005-01-01

    The most difficult unsolved problem in fundamental theoretical physics is the consistent implementation of the gravitational interaction into a quantum framework, which would lead to a theory of quantum gravity. Although a final answer is still pending, several promising attempts do exist. Despite the general title, this book is about one of them - loop quantum gravity. This approach proceeds from the idea that a direct quantization of Einstein's theory of general relativity is possible. In contrast to string theory, it presupposes that the unification of all interactions is not needed as a prerequisite for quantum gravity. Usually one divides theories of quantum general relativity into covariant and canonical approaches. Covariant theories employ four-dimensional concepts in its formulation, one example being the path integral approach. Canonical theories start from a classical Hamiltonian version of the theory in which spacetime is foliated into spacelike hypersurfaces. Loop quantum gravity is a variant of the canonical approach, the oldest being quantum geometrodynamics where the fundamental configuration variable is the three-metric. Loop quantum gravity has developed from a new choice of canonical variables introduced by Abhay Ashtekar in 1986, the new configuration variable being a connection defined on a three-manifold. Instead of the connection itself, the loop approach employs a non-local version in which the connection is integrated over closed loops. This is similar to the Wilson loops used in gauge theories. Carlo Rovelli is one of the pioneers of loop quantum gravity which he started to develop with Lee Smolin in two papers written in 1988 and 1990. In his book, he presents a comprehensive and competent overview of this approach and provides at the same time the necessary technical background in order to make the treatment self-contained. In fact, half of the book is devoted to 'preparations' giving a detailed account of Hamiltonian mechanics, quantum mechanics, general relativity and other topics. According to the level of the reader, this part can be skipped or studied as interesting material on its own. The penetrating theme of the whole book (its leitmotiv) is background independence. In non-gravitational theories, dynamical fields are formulated on a fixed background spacetime that plays the role of an absolute structure in the theory. In general relativity, on the other hand, there is no background structure - all fields are dynamical. This was a confusing point already during the development of general relativity and led Albert Einstein in 1913 erroneously to give up general covariance before recognizing his error and presenting his final correct field equations that are of course covariant. This story is instructive, circling around the famous 'hole problem', and is told in detail in Rovelli's book. Its solution is that points on a bare manifold do not make sense in physics; everything, including the gravitational field, is dragged around by a diffeomorphism - there is just no background available, only the fields exist. In loop quantum gravity, physical space (called 'quantum geometry') itself is formed by loop-like quantum states: a suitable orthonormal basis is provided by spin-network states (a spin-network is a graph with edges and nodes, where spins are assigned to the edges), and the quantum geometry is a superposition of such states. Time and space in the usual sense have disappeared. In the second half of his book, Rovelli discusses at length the major successes of this approach. First of all, the formalism yields a unique kinematical Hilbert space for the quantum states obeying the Gauss and diffeomorphism constraints. Secondly, there exist two important operators that are connected, respectively, with area and volume in the classical limit. These operators have a discrete spectrum and thus provide elementary 'quanta' of area and volume. This gives a vague hint of a discrete structure at the Planck scale, about which there were speculations for many decades. In spite of these promising results, loop quantum gravity is still far away from a physical theory. This is also reflected in this volume where the technical treatment prevails and where physical applications are relegated to about 20 pages. These applications deal with quantum cosmology and black holes. The part on loop quantum cosmology summarizes briefly recent results about a possible singularity avoidance and a new mechanism for inflation. These results are not derived from loop quantum gravity but from imposing the discrete structure of the full theory directly on the quantum cosmological models. The part on black holes discusses the derivation of the Bekenstein-Hawking entropy from counting the number of relevant spin-network states. Since the theory contains a free parameter (the 'Barbero-Immirzi parameter'), the best one can do is to determine this parameter by demanding that the result be the Bekenstein-Hawking entropy. The book does not yet contain the results of recent papers, published in 2004, that correct the earlier entropy calculations presented here. From the new value of the Barbero-Immirzi parameter, the appealing connection with quasi-normal modes, as discussed in the book, may be lost. The book concludes with a brief discussion of the major open issues. The present volume gives both an introduction and a review of this approach, making it suitable for advanced students as well as experts. It is certainly of interest for the readers of Classical and Quantum Gravity. (book review)

  6. The Cambridge photographic atlas of galaxies

    CERN Document Server

    König, Michael

    2017-01-01

    Galaxies - the Milky Way's siblings - offer a surprising variety of forms and colours. Displaying symmetrical spiral arms, glowing red nebulae or diffuse halos, even the image of a galaxy can reveal much about its construction. All galaxies consist of gas, dust and stars, but the effects of gravity, dark matter and the interaction of star formation and stellar explosions all influence their appearances. This volume showcases more than 250 of the most beautiful galaxies within an amateur's reach and uses them to explain current astrophysical research. It features fantastic photographs, unique insights into our knowledge, tips on astrophotography and essential facts and figures based on the latest science. From the Andromeda Galaxy to galaxy clusters and gravitational lenses, the nature of galaxies is revealed through these stunning amateur photographs. This well illustrated reference atlas deserves a place on the bookshelves of astronomical imagers, observers and armchair enthusiasts.

  7. The Cambridge Handbook of Multimedia Learning

    Directory of Open Access Journals (Sweden)

    Malbrán, María del Carmen

    2007-01-01

    Full Text Available Durante la última década el campo del aprendizaje multimediado ha emergido como una disciplina coherente basada en la investigación. El Manual presenta un panorama actualizado y comprensivo de ambos. Este tipo de aprendizaje tiene lugar a través de palabras (textos orales e impresos e imágenes (ilustraciones, fotografías, mapas, animaciones, video. El Manual se centra en el modo en que se aprende con estos recursos en contextos mediados por la computadora.

  8. Fifty years ago - nuclear physics at Cambridge

    International Nuclear Information System (INIS)

    Burcham, W.E.

    1982-01-01

    Fifty years ago, the Cavendish saw the first nuclear transformations using artificially accelerated particles, and was soon to provide confirmation of the discovery of the positron. In 1932, the Cavendish Laboratory under the guiding hand of Rutherford was a world focus for research and with these discoveries saw the birth of modern particle physics. (orig.).

  9. The new Cambridge companion to Shakespeare

    OpenAIRE

    2015-01-01

    Written by a team of leading international scholars, this Companion is designed to illuminate Shakespeare's works through discussion of the key topics of Shakespeare studies. Twenty-one brand new essays provide lively and authoritative approaches to recent scholarship and criticism for readers keen to expand their knowledge and appreciation of Shakespeare. The book contains stimulating chapters on traditional topics such as Shakespeare's biography and the transmission of his texts. Individual...

  10. (Review of) Reno, William. 2011. Warfare in Independent Africa. Cambridge: Cambridge University Press

    DEFF Research Database (Denmark)

    Hagmann, Tobias

    2013-01-01

    Warfare in Independent Africa is Reno’s bold attempt to analyze the modern history of African insurgencies. The book tackles this task through the prism of five generations of rebel, which left their mark on the continent; anti-colonial rebels, majority rule rebels, reform rebels, warlord rebels ...... and parochial rebels....

  11. Characterising non-covalent interactions with the Cambridge Structural Database.

    Science.gov (United States)

    Lommerse, J P; Taylor, R

    1997-02-01

    This review describes how the CSD can be used to study non-covalent interactions. Several different types of information may be obtained. First, the relative frequencies of various interactions can be studied; for example, we have shown that the terminal oxygen atoms of phosphate groups accept hydrogen bonds far more often than the linkage oxygens. Secondly, information can be obtained about the geometries of nonbonded contacts; for example, hydrogen bonds to P-O groups rarely form along the extension of the P-O bond, whereas short contacts between oxygen and carbon-bound iodine show a strong preference for linear C-I ... O angles. Thirdly, the CSD can be searched for novel interactions which may be exploited in inhibitor design; for example, the I ... O contacts just mentioned, and N-H ... pi hydrogen bonds. Finally, the CSD can suggest synthetic targets for medicinal chemistry; for example, molecules containing delocalised electron deficient groups such as trimethylammonium, pyridinium, thaizolium and dinitrophenyl have a good chance of binding to an active-site tryptophan. Although the CSD contains small-molecule crystal structures, not protein-ligand complexes, there is considerable evidence that the contacts seen in the two types of structures are similar. We have illustrated this a number of times in the present review and additional evidence has been given previously by Klebe. The major advantages of the CSD are its size, diversity and experimental accuracy. For these reasons, it is a useful tool for modellers engaged in rational inhibitor design.

  12. Residencia para enfermeras en Cambridge Gran Bretaña

    Directory of Open Access Journals (Sweden)

    Thurlow, David

    1977-12-01

    Full Text Available This residence, consisting of two floors and a l-shaped layout with wings of equal length, houses two independent apartments on the lower level and twelve dormitory type rooms equipped with bathrooms and kitchens common to every two rooms on the ground floor and to every four on the upper level. The project is characterized by its simplicity of design, which strives to harmonize the new structure, both in the materials and in the formal approach, with the traditional architecture present in the surroundings. In this direction, fundamentally, the solution adopted for the roof —covered with slate— stands out, which are interrupted for window openings and to provide abundant lighting for the central distributing corridor on the first floor which is distant from the perimeter. The achievements in the functional design are integrated into a pleasant and attractive solution which can be appreciated from both the inside and the outside.Esta Residencia, de dos niveles de altura y planta configurada como una «L» de brazos iguales, alberga dos apartamentos independientes en el nivel inferior, y doce salones-dormitorio, dotados de servicios de baño y cocina comunes a cada dos dormitorios, en planta baja, y a cada cuatro, en el nivel superior. El proyecto se caracteriza por su sencillez de diseño, que procura armonizar la nueva construcción, tanto en los materiales como en el planteamiento formal, con la arquitectura tradicional existente en el entorno. En este sentido se destaca, fundamentalmente, la solución adoptada para la cubierta, revestida de pizarra, que se interrumpe para abrir huecos de ventana y para iluminar abundantemente el corredor central de distribución en la planta primera, alejado del perímetro. Los logros en la solución funcional se integran en un diseño agradable y atractivo, apreciable tanto interior como exteriormente.

  13. Masters of Theory Cambridge and the Rise of Mathematical Physics

    CERN Document Server

    Warwick, Andrew

    2011-01-01

    Winner of the the Susan Elizabeth Abrams Prize in History of Science.When Isaac Newton published the Principia three centuries ago, only a few scholars were capable of understanding his conceptually demanding work. Yet this esoteric knowledge quickly became accessible in the nineteenth and early twentieth centuries when Britain produced many leading mathematical physicists. In this book, Andrew Warwick shows how the education of these "masters of theory" led them to transform our understanding of everything from the flight of a boomerang to the structure of the universe. Warwick focuses on Cam

  14. Stephanie Lynn Budin: The Myth of Sacred Prostitution in Antiquity. Cambridge u.a.: Cambridge University Press 2008. Stephanie Lynn Budin: The Myth of Sacred Prostitution in Antiquity. Cambridge u.a.: Cambridge University Press 2008.

    Directory of Open Access Journals (Sweden)

    Julian Herbert Köck

    2010-03-01

    Full Text Available Stephanie Lynn Budin liefert mit vorliegender Studie einen wichtigen Beitrag zur Debatte um die Existenz von Tempelprostitution im Altertum. Systematisch untersucht sie die Quellen zur Tempelprostitution und kann weitgehend überzeugend darlegen, dass die betreffenden Stellen nicht für die Existenz von Tempelprostitution im Altertum sprechen, sondern nur aufgrund von tendenziösen Interpretationen so verstanden wurden. Dabei greift die Studie die Ergebnisse anderer Wissenschaftler/-innen auf, bietet aber – besonders zu Herodot und Strabon – auch neue Erkenntnisse.Stephanie Lynn Budin’s study offers up an important contribution to the debate on the existence of temple prostitution during antiquity. She systematically examines the sources on temple prostitution and can demonstrate, fairly convincingly, that the passages in question do not prove the existence of temple prostitution during antiquity, but instead have been merely understood to do so based on tendentious interpretations. In so doing, the study takes up conclusions offered by other scholars, but it also provides – especially when it comes to Herodotus and Strabo – new insights.

  15. Asian Pacific Americans in Cambridge. Community Profiles in Massachusetts.

    Science.gov (United States)

    Massachusetts Univ., Boston. Inst. for Asian American Studies.

    The Community Profiles Project uses data from the 1990 U.S. Census to describe some of the population characteristics of Asian Pacific Americans in selected Massachusetts cities and towns. The profiles include basic statistics relating to income, employment, education, and housing. This information can assist policy makers and practitioners in…

  16. Esther Schor, ed. The Cambridge Companion to Mary Shelley

    Directory of Open Access Journals (Sweden)

    Anne BERTON

    2006-06-01

    Full Text Available “Today, whether she is found between staid cloth covers, in paperback, on the screen or in cyberspace, Mary Shelley is everywhere,” writes Esther Schor in her Introduction to this collection of essays (2. Interest in “the Author of Frankenstein” and of other works has grown steadily over the last twenty years, thanks notably to the publication of her Journals (The Journals of Mary Shelley, 1814-1844, ed. Paula R. Feldman and Diana Scott-Kilvert, 2 vols, Oxford: Clarendon, 1987, of her Lette...

  17. Cambridge journals blog: Improving feed efficiency in dairy production

    Science.gov (United States)

    Because the cost of feeding animals is one of the greatest expenses in dairy production (40-60% of production costs), research focused on ways to identify and select for animals that are the most efficient at converting feed into milk has greatly expanded during the last decade. The animal Article o...

  18. Language and the Brain. Cambridge Approaches to Linguistics.

    Science.gov (United States)

    Obler, Loraine K.; Gjerlow, Kris

    This book examines how the brain enables people to speak creatively and build up an understanding of language. The discussion looks at the linguistic and neuro-anatomical underpinnings of language and considers how language skills can systematically break down in individuals with different types of brain damage. By studying children with language…

  19. Joint Services Electronics Program (Harvard University. Cambridge, Massachusetts)

    Science.gov (United States)

    1988-09-30

    34Band Structures of Semimagnetic Compounds," Acta Physica Polonica bf A73 (6), 933-941 (1988). (Partially supported by N00014-86-K-0760). c. Books...Journals K.L. Babcock and R.M. Westervelt, "Dynamics of Simple Electronic neural Net- works," Physica 28D, 305 (1987). C.M. Marcus and R.M. Westervelt

  20. book review the cambridge guide to african ano caribbean theatre.

    African Journals Online (AJOL)

    looks good, and feels good. A question immediately presents itself: it this a ploy to divide up and profit from World Theatre, or is it a serious extension of an unfinished ... to redress the tendency to adopt a Eurocentric view the volume tolerates dated and slipshod work of a kind that. Journal ef.H1;1manities, Nos 819, 1994195.

  1. Book Review "Cambridge handbook of experimental political science"

    NARCIS (Netherlands)

    Grimmelikhuijsen, Stephan

    2014-01-01

    Experimentation has formed the basis for modern scientific discovery. Francis Bacon (1561– 1626), “the father of empiricism,” was one of the first to propose a method of science based on experimentation that results in new theories that can again be tested by experimentation. At first, experiments

  2. The industrial application requirement for biotech inventions in light of recent EPO & UK case law:

    DEFF Research Database (Denmark)

    Minssen, Timo; Nilsson, David

    2012-01-01

    In this study we illuminate and discuss the most recent developments in respect of the interpretation of the “industrial application” requirement with respect to gene and protein related inventions in Europe. The analysis will focus on the relevant provisions of the EPC and decisional practice from...... the European Patent Organisation (“EPO”), particularly decisions from the Technical Board of Appeal 3.3.08 (the “Board”). To get a glimpse of the national dimension, we will also look at the first patent judgment from the "new" UK Supreme Court, i.e. the groundbreaking decision in HGS v Eli Lilly, In the final...... discussion, we will elaborate on two issues in particular; (i) determine which types of qualities an invention should have in order to meet the industrial application requirement in the first place; and (ii) what type of evidence an applicant is expected to present in respect of (potential) applications...

  3. Validation of cross-contamination control in biological safety cabinet for biotech/pharmaceutical manufacturing process.

    Science.gov (United States)

    Hu, Shih-Cheng; Shiue, Angus; Tu, Jin-Xin; Liu, Han-Yang; Chiu, Rong-Ben

    2015-12-01

    For class II, type A2 biological safety cabinets (BSC), NSF/ANSI Standard 49 should be conformed in cabinet airflow velocity derivation, particle contamination, and aerodynamic flow properties. However, there exists a potential problem. It has been built that the cabinet air flow stabilize is influenced by the quantity of downflow of air and the height above the cabinet exhaust opening. Three air downflow quantities were compared as an operating apparatus was placed from 20 to 40 cm above the bench of the cabinet. The results show that the BSC air downflow velocity is a function of increased sampling height, displaying that containment is improvingly permitted over product protection as the sampling height decreases. This study investigated the concentration gradient of particles at various heights and downflow air quantity from the bench of the BSC. Experiment results indicate that performance near the bench was better than in the rest of the BSC. In terms of height, the best cleanliness was measured at a height of 10 cm over the bench; it reduced actually with add in height. The empirical curves accommodate, founded on the concentration gradient of particle created was elaborated for evaluating the particle concentration at different heights and downflow air quantity from the source of the bench of the BSC. The particle image velocimetry system applied for BSC airflow research to fix amount of airflow patterns and air distribution measurement and results of measurements show how obstructions can greatly influence the airflow and contaminant transportation in a BSC.

  4. Process-driven information management system at a biotech company: concept and implementation.

    Science.gov (United States)

    Gobbi, Alberto; Funeriu, Sandra; Ioannou, John; Wang, Jinyi; Lee, Man-Ling; Palmer, Chris; Bamford, Bob; Hewitt, Robin

    2004-01-01

    While established pharmaceutical companies have chemical information systems in place to manage their compounds and the associated data, new startup companies need to implement these systems from scratch. Decisions made early in the design phase usually have long lasting effects on the expandability, maintenance effort, and costs associated with the information management system. Careful analysis of work and data flows, both inter- and intradepartmental, and identification of existing dependencies between activities are important. This knowledge is required to implement an information management system, which enables the research community to work efficiently by avoiding redundant registration and processing of data and by timely provision of the data whenever needed. This paper first presents the workflows existing at Anadys, then ARISE, the research information management system developed in-house at Anadys. ARISE was designed to support the preclinical drug discovery process and covers compound registration, analytical quality control, inventory management, high-throughput screening, lower throughput screening, and data reporting.

  5. The Sociology of the Gene: Genetics and Education on the Eve of the Biotech Century.

    Science.gov (United States)

    Rifkin, Jeremy

    1998-01-01

    Researchers in molecular biology are discovering an increasing genetic basis for a wide range of mental diseases, moods, behaviors, and personality traits. Findings are creating the context for a new sociobiology favoring a genetic interpretation of human motivations and drives. Genetic engineering will give some people unprecedented power over…

  6. 2012 in review - part II: overcoming the obstacles in the pharma/biotech industry.

    Science.gov (United States)

    Rabasseda, X; Dulsat, C; Navarro, D; Cruces, E; Graul, A I; Jago, C; Tracy, M

    2013-02-01

    As highlighted in the first part of this review published last month, the year 2012 saw the approval of a remarkable number of new drugs, and among the new drugs reaching the market, a significant proportion were orphan drugs developed for treating less prevalent diseases. These drugs are certainly not expected to become blockbusters, but are of high interest because of their efficacy in a narrow spectrum of patients. This trend aligns with the general tendency of staying away from fit-for-all blockbusters into personalized medicine as one of the strategies for overcoming the patent cliff that resulted in a long list of drugs going off patent and being approved as generics also during last year. The emerging scenario resulting from new developments in the form of new drugs and biosimilars and newly available generic medications paralleled by strategic movements within the pharmaceutical industry to reinforce their position in the market, as reflected by merger and acquisition deals accompanied by significant efforts into prioritization resulting in spin-off and split transactions, is reviewed in this second part. This paper includes a significant amount of data in tables for quick review and to profile the new strategic movements in drug pipelines. Further information, including details on mechanisms of action, current status, itemized pharmacology, pharmacokinetic and clinical trial research findings and updated information can be found in the proprietary databases Thomson Reuters Integrity(SM) and Thomson Reuters Cortellis™. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

  7. Who benefits from gm crops? Feeding the biotech giants, not the world's poor

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Villar, J.; Freese, B.; Holder, H.; Chandrasekaran, K.; Rodriguez, L.

    2009-02-15

    The biotechnology industry has aggressively touted GM as a solution to hunger and the global food crisis. Their arguments have been accepted by many politicians. This Friends of the Earth International (FoEI) report looks behind the spin and exposes the reasons why GM crops cannot, and are unlikely to ever, contribute to poverty reduction, global food security or sustainable farming (authors' abstract)

  8. Blueprints for green biotech: development and application of standards for plant synthetic biology.

    Science.gov (United States)

    Patron, Nicola J

    2016-06-15

    Synthetic biology aims to apply engineering principles to the design and modification of biological systems and to the construction of biological parts and devices. The ability to programme cells by providing new instructions written in DNA is a foundational technology of the field. Large-scale de novo DNA synthesis has accelerated synthetic biology by offering custom-made molecules at ever decreasing costs. However, for large fragments and for experiments in which libraries of DNA sequences are assembled in different combinations, assembly in the laboratory is still desirable. Biological assembly standards allow DNA parts, even those from multiple laboratories and experiments, to be assembled together using the same reagents and protocols. The adoption of such standards for plant synthetic biology has been cohesive for the plant science community, facilitating the application of genome editing technologies to plant systems and streamlining progress in large-scale, multi-laboratory bioengineering projects. © 2016 The Author(s). published by Portland Press Limited on behalf of the Biochemical Society.

  9. Research in Undergraduate Instruction: A Biotech Lab Project for Recombinant DNA Protein Expression in Bacteria

    Science.gov (United States)

    Brockman, Mark; Ordman, Alfred B.; Campbell, A. Malcolm

    1996-06-01

    In the sophomore-level Molecular Biology and Biotechnology course at Beloit College, students learn basic methods in molecular biology in the context of pursuing a semester-long original research project. We are exploring how DNA sequence affects expression levels of proteins. A DNA fragment encoding all or part of the guanylate monokinase (gmk) sequence is cloned into pSP73 and expressed in E. coli. A monoclonal antibody is made to gmk. The expression level of gmk is determined by SDS gel elctrophoresis, a Western blot, and an ELISA assay. Over four years, an increase in enrollment in the course from 9 to 34 students, the 85% of majors pursuing advanced degrees, and course evaluations all support the conclusion that involving students in research during undergraduate courses encourages them to pursue careers in science.

  10. Additive Biotech-Chances, challenges, and recent applications of additive manufacturing technologies in biotechnology.

    Science.gov (United States)

    Krujatz, Felix; Lode, Anja; Seidel, Julia; Bley, Thomas; Gelinsky, Michael; Steingroewer, Juliane

    2017-10-25

    The diversity and complexity of biotechnological applications are constantly increasing, with ever expanding ranges of production hosts, cultivation conditions and measurement tasks. Consequently, many analytical and cultivation systems for biotechnology and bioprocess engineering, such as microfluidic devices or bioreactors, are tailor-made to precisely satisfy the requirements of specific measurements or cultivation tasks. Additive manufacturing (AM) technologies offer the possibility of fabricating tailor-made 3D laboratory equipment directly from CAD designs with previously inaccessible levels of freedom in terms of structural complexity. This review discusses the historical background of these technologies, their most promising current implementations and the associated workflows, fabrication processes and material specifications, together with some of the major challenges associated with using AM in biotechnology/bioprocess engineering. To illustrate the great potential of AM, selected examples in microfluidic devices, 3D-bioprinting/biofabrication and bioprocess engineering are highlighted. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Scientific Advances with Aspergillus Species that Are Used for Food and Biotech Applications.

    Science.gov (United States)

    Biesebeke, Rob Te; Record, Erik

    2008-01-01

    Yeast and filamentous fungi have been used for centuries in diverse biotechnological processes. Fungal fermentation technology is traditionally used in relation to food production, such as for bread, beer, cheese, sake and soy sauce. Last century, the industrial application of yeast and filamentous fungi expanded rapidly, with excellent examples such as purified enzymes and secondary metabolites (e.g. antibiotics), which are used in a wide range of food as well as non-food industries. Research on protein and/or metabolite secretion by fungal species has focused on identifying bottlenecks in (post-) transcriptional regulation of protein production, metabolic rerouting, morphology and the transit of proteins through the secretion pathway. In past years, genome sequencing of some fungi (e.g. Aspergillus oryzae, Aspergillus niger) has been completed. The available genome sequences have enabled identification of genes and functionally important regions of the genome. This has directed research to focus on a post-genomics era in which transcriptomics, proteomics and metabolomics methodologies will help to explore the scientific relevance and industrial application of fungal genome sequences.

  12. The global competition for talent: Life science and biotech careers, international mobility, and competitiveness

    NARCIS (Netherlands)

    Kuvik, A.N.

    2015-01-01

    This study argues that skilled human mobility and specifically that for occupations linked to innovation, such as for science and technology, has undergone a rapid and continuing internationalization. This change has theoretical implications and requires a greater merging of theories in diverse

  13. Coaching Small Biotech Companies into Success: The Value-adding Function of VC

    OpenAIRE

    Terttu Luukkonen,; Mari Maunula,

    2006-01-01

    The paper reports an empirical study on the non-financial value-added provided by Venture Capital investors to their investee firms. This study will use a four-class grouping of the various non-financial value-adding capabilities provided by VC firms, namely, scouting, monitoring, signalling and value-adding services. The study examines biotechnology industry in Finland. Finland has a dual system with independent (partially ever-green) VC companies and public or semi-public VC organisations. ...

  14. [European Marketing Authorisation: a long process. Experiences of small biotech companies with the ATMP regulation].

    Science.gov (United States)

    Buljovčić, Z

    2011-07-01

    On 30 December 2008, the Regulation (EC) 1394/2007 on advanced therapy medicinal products (ATMPs) entered into force. Herewith the first EU-wide regulatory framework for ATMPs was established. It requires a central marketing authorisation application to the EMA (European Medicinal Agency). This new framework especially changes the code of regulatory practice for tissue engineered products (TEPs), as no registration procedure had been previously required for autologous TEPs. This also meant that no clinical proof of efficacy achieved by a pivotal clinical trial was necessary. Difficulties and their background as well as the vast requirements for product development that have to be addressed by small companies within a very short time frame are presented. Hereby, it is obvious that regulatory experience which is required to identify and implement the resulting implications was not in place yet and still had to be established. The lack of regulatory experience also resulted in difficulties with scientific advice preparation, expectations toward regulatory agencies, consultants, and transformation of regulatory requirements. Addressing the regulatory requirements within the transition period is even more difficult for entrepreneurs with products which are assigned for indications resulting in complex challenges to the trial design. Due to the enormous time pressure to generate data and due to the implied financial pressure, different adaptation strategies are evolving. In Germany the "hospital exemption" according to §4b AMG (German Medicinal Products Law) is of major importance. A reorientation toward acellular products and a slow down in development of new ATMP products is expected.

  15. Who benefits from gm crops? Feeding the biotech giants, not the world's poor

    International Nuclear Information System (INIS)

    Lopez Villar, J.; Freese, B.; Holder, H.; Chandrasekaran, K.; Rodriguez, L.

    2009-02-01

    The biotechnology industry has aggressively touted GM as a solution to hunger and the global food crisis. Their arguments have been accepted by many politicians. This Friends of the Earth International (FoEI) report looks behind the spin and exposes the reasons why GM crops cannot, and are unlikely to ever, contribute to poverty reduction, global food security or sustainable farming (authors' abstract)

  16. How to practice creative thinking skills through scaffolding on biotech content?

    Science.gov (United States)

    Natadiwijaya, I. F.; Rahmat, A.; Redjeki, S.; Anggraeni, S.

    2018-05-01

    Biotechnology content is a more applicative field of science, so learners should be able to have creative thinking skills in applying concepts to problem solving. In this research, Scaffolding learning has been conducted, which is student form of concept development based on constructivism learning paradigm and students build creative thinking skill through the creation of biotechnology product ideas. The research design was R & D method. The subject of this research is a semester V biology education student at Wiralodra University. The instruments used are biotechnology creative thinking tests and program implementation observations. The data of creative thinking test was analyzed using inferential statistic, while the observation sheet used descriptive analysis. The result of this research is the result of students’ creative thinking skill as well as description of the recommended shape and characteristics of the program, with the following results. The scaffolding learning program has a significant influence on students’ creative thinking skill, and the program that trains creative thinking skill is built through two phases, namely phase 1 in concept building where students build their own knowledge, and phase 2 where students build thinking skills creatively through the creation of biotechnology product ideas.

  17. Market entry and exit by biotech and device companies funded by venture capital.

    Science.gov (United States)

    Burns, Lawton R; Housman, Michael G; Robinson, Charles A

    2009-01-01

    Start-up companies in the biotechnology and medical device sectors are important sources of health care innovation. This paper describes the role of venture capital in supporting these companies and charts the growth in venture capital financial support. The paper then uses longitudinal data to describe market entry and exit by these companies. Similar factors are associated with entry and exit in the two sectors. Entries and exits in one sector also appear to influence entry in the other. These findings have important implications for developing innovative technologies and ensuring competitive markets in the life sciences.

  18. A Quantitative PCR-Electrochemical Genosensor Test for the Screening of Biotech Crops

    Directory of Open Access Journals (Sweden)

    Suely Moura-Melo

    2017-04-01

    Full Text Available The design of screening methods for the detection of genetically modified organisms (GMOs in food would improve the efficiency in their control. We report here a PCR amplification method combined with a sequence-specific electrochemical genosensor for the quantification of a DNA sequence characteristic of the 35S promoter derived from the cauliflower mosaic virus (CaMV. Specifically, we employ a genosensor constructed by chemisorption of a thiolated capture probe and p-aminothiophenol gold surfaces to entrap on the sensing layer the unpurified PCR amplicons, together with a signaling probe labeled with fluorescein. The proposed test allows for the determination of a transgene copy number in both hemizygous (maize MON810 trait and homozygous (soybean GTS40-3-2 transformed plants, and exhibits a limit of quantification of at least 0.25% for both kinds of GMO lines.

  19. Ross, Robert. – A Concise History of South Africa. Cambridge, Cambridge University Press, 1999, 219 p., index, bibl. (« Cambridge Concise Histories »).

    OpenAIRE

    Creusat, Laurence

    2003-01-01

    Robert Ross, maître de conférence à l'université de Leiden, écrit et publie depuis vingt ans des ouvrages sur l'histoire de l'Afrique du Sud. Son dernier livre qui prend comme point de départ l'introduction de l'agriculture dans ce pays, il y a de cela 1 500 ans, et le conclut avec l'arrivée à la présidence de N. Mandela, est un bel exemple d'étude synthétique réussie sur l'histoire de ce pays. Le mérite de ce livre est de montrer clairement comment le passé explique le présent, commen...

  20. International conference on the photochemical conversion and storage of solar energy, 2nd, Cambridge University, Cambridge, England, August 10-12, 1978, Lectures

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    Articles are presented on energy storage in organic photoisomers, light induced electron transfer reactions, photogalvanic cells, as well as on photoelectrochemistry and heterogeneous photocatalysis at semiconductors. Other subjects include the physics and chemistry of solar cells and synthetic molecular organizates.

  1. 2012 AAPS National Biotech Conference Open Forum: a perspective on the current state of immunogenicity prediction and risk management.

    Science.gov (United States)

    Rajadhyaksha, Manoj; Subramanyam, Meena; Rup, Bonnie

    2013-10-01

    The immunogenicity profile of a biotherapeutic is determined by multiple product-, process- or manufacturing-, patient- and treatment-related factors and the bioanalytical methodology used to monitor for immunogenicity. This creates a complex situation that limits direct correlation of individual factors to observed immunogenicity rates. Therefore, mechanistic understanding of how these factors individually or in concert could influence the overall incidence and clinical risk of immunogenicity is crucial to provide the best benefit/risk profile for a given biotherapeutic in a given indication and to inform risk mitigation strategies. Advances in the field of immunogenicity have included development of best practices for monitoring anti-drug antibody development, categorization of risk factors contributing to immunogenicity, development of predictive tools, and development of effective strategies for risk management and mitigation. Thus, the opportunity to ask "where we are now and where we would like to go from here?" was the main driver for organizing an Open Forum on Improving Immunogenicity Risk Prediction and Management, conducted at the 2012 American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference in San Diego. The main objectives of the Forum include the following: to understand the nature of immunogenicity risk factors, to identify analytical tools used and animal models and management strategies needed to improve their predictive value, and finally to identify collaboration opportunities to improve the reliability of risk prediction, mitigation, and management. This meeting report provides the Forum participant's and author's perspectives on the barriers to advancing this field and recommendations for overcoming these barriers through collaborative efforts.

  2. Teaching and implementing autonomous robotic lab walkthroughs in a biotech laboratory through model-based visual tracking

    Science.gov (United States)

    Wojtczyk, Martin; Panin, Giorgio; Röder, Thorsten; Lenz, Claus; Nair, Suraj; Heidemann, Rüdiger; Goudar, Chetan; Knoll, Alois

    2010-01-01

    After utilizing robots for more than 30 years for classic industrial automation applications, service robots form a constantly increasing market, although the big breakthrough is still awaited. Our approach to service robots was driven by the idea of supporting lab personnel in a biotechnology laboratory. After initial development in Germany, a mobile robot platform extended with an industrial manipulator and the necessary sensors for indoor localization and object manipulation, has been shipped to Bayer HealthCare in Berkeley, CA, USA, a global player in the sector of biopharmaceutical products, located in the San Francisco bay area. The determined goal of the mobile manipulator is to support the off-shift staff to carry out completely autonomous or guided, remote controlled lab walkthroughs, which we implement utilizing a recent development of our computer vision group: OpenTL - an integrated framework for model-based visual tracking.

  3. The value of trust in biotech crop development: a case study of Bt cotton in Burkina Faso

    Directory of Open Access Journals (Sweden)

    Ezezika Obidimma C

    2012-11-01

    Full Text Available Abstract Background Agricultural biotechnology public-private partnerships (PPPs have been recognized as having great potential in improving agricultural productivity and increasing food production in sub-Saharan Africa. However, there is much public skepticism about the use of GM (genetically modified crops and suspicion about private sector involvement in agbiotech projects. This case study sought to understand the role of trust in the Bacillus thuringiensis (Bt cotton in Burkina Faso project by exploring practices and challenges associated with trust-building, and determining what makes these practices effective from the perspective of multiple stakeholders. Methods We conducted semi-structured, face-to-face interviews to obtain stakeholders’ understanding of trust in general as well as in the context of agbiotech PPPs. Relevant documents and articles were analyzed to generate descriptions of how trust was operationalized in this evolving agbiotech PPP. Data was analyzed based on emergent themes to create a comprehensive narrative on how trust is understood and built among the partners and with the community. Results We derived four key lessons from our findings. First, strong collaboration between research, industry and farmers greatly contributes to both the success of, and fostering of trust in, the partnership. Second, this case study also revealed the important, though often unrecognized, role of researchers as players in the communication strategy of the project. Third, effective and comprehensive communication takes into account issues such as illiteracy and diversity. Fourth, follow-up at the field level and the need for a multifaceted communications strategy is important for helping push the project forward. Conclusions Burkina Faso’s well-established and effective cotton selling system laid the foundation for the implementation of the Bt cotton project – particularly, the strong dialogue and the receptivity to collaboration. Interviewees reported that establishing and maintaining trust among partners, researchers and the community in Burkina Faso greatly contributed to the success of the PPP. By addressing challenges to building trust and engaging in trust-building practices early on, improvements in the effectiveness of agbiotech PPPs are likely.

  4. R&D INTENSITY AND IPO UNDERPRICING: CASE STUDY ON PHARMACEUTICAL AND BIOTECH INDUSTRIES IN THE US

    Directory of Open Access Journals (Sweden)

    Tommy C. Efrata

    2016-02-01

    Full Text Available Asymmetric information between the issuer to potential investors believed by some academics in finance as one of the main causes of the phenomenon of underpricing at the time of the initial public offering (IPO. On science and technology-based company main problem lies in how to conduct assessments on the future value of a product that is still in the development stage. The issue became more prominent on pharmaceutical companies and biotechnology, due to the characteristics of this industry is the high expense, complex process, and the lengthy process of research and development (R & D of a product. This study describes the characteristics above is associated with the phenomenon of underpricing when companies conduct IPO. The samples are 82 pharmaceutical companies and biotechnology conduct IPO in the United States stock market in 1998-2005. The results of this study revealed a negative correlation between the intensity of R & D and IPO underpricing phenomenon in this industry. These studies have identified R & D as the main source of information asymmetry that led to the phenomenon of underpricing for pharmaceutical companies and biotechnology.

  5. Analytical criteria for performance characteristics of IgE binding methods for evaluating safety of biotech food products

    NARCIS (Netherlands)

    Holzhauser, Thomas; van Ree, Ronald; Poulsen, Lars K.; Bannon, Gary A.

    2008-01-01

    There is detailed guidance on how to perform bioinformatic analyses and enzymatic degradation studies for genetically modified crops under consideration for approval by regulatory agencies; however, there is no consensus in the scientific community on the details of how to perform IgE serum studies.

  6. Electrochemical sensor for multiplex screening of genetically modified DNA: identification of biotech crops by logic-based biomolecular analysis.

    Science.gov (United States)

    Liao, Wei-Ching; Chuang, Min-Chieh; Ho, Ja-An Annie

    2013-12-15

    Genetically modified (GM) technique, one of the modern biomolecular engineering technologies, has been deemed as profitable strategy to fight against global starvation. Yet rapid and reliable analytical method is deficient to evaluate the quality and potential risk of such resulting GM products. We herein present a biomolecular analytical system constructed with distinct biochemical activities to expedite the computational detection of genetically modified organisms (GMOs). The computational mechanism provides an alternative to the complex procedures commonly involved in the screening of GMOs. Given that the bioanalytical system is capable of processing promoter, coding and species genes, affirmative interpretations succeed to identify specified GM event in terms of both electrochemical and optical fashions. The biomolecular computational assay exhibits detection capability of genetically modified DNA below sub-nanomolar level and is found interference-free by abundant coexistence of non-GM DNA. This bioanalytical system, furthermore, sophisticates in array fashion operating multiplex screening against variable GM events. Such a biomolecular computational assay and biosensor holds great promise for rapid, cost-effective, and high-fidelity screening of GMO. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Chemistry of fossil fuels and biofuels (cambridge series in chemical engineering)

    CERN Document Server

    Schobert, Harold

    2013-01-01

    Focusing on today's major fuel resources - ethanol, biodiesel, wood, natural gas, petroleum products and coal - this book discusses the formation, composition and properties of the fuels, and the ways in which they are processed for commercial use. The book examines the origin of fuels through natural processes such as photosynthesis and the geological transformation of ancient plant material; the relationships between their composition, molecular structures, and physical properties; and the various processes by which they are converted or refined into the fuel products appearing on today's market. Fundamental chemical aspects such as catalysis and the behaviour of reactive intermediates are presented, and global warming and anthropogenic carbon dioxide emissions are also discussed. The book is suitable for graduate students in energy engineering, chemical engineering, mechanical engineering and chemistry, as well as professional scientists and engineers.

  8. GPS Antenna Data Needed : GPS Adjacent Band Compatibility Workshop Volpe Center, Cambridge MA

    Science.gov (United States)

    2014-09-18

    Topics. 1. Technical Objective: Receiver Antenna Mask and Electronics Data. 2. Definition of Receiver Antenna Mask. 3. Use of Receiver Antenna Mask. 4. Approaches to Generate the Antenna Mask. 5. Request for Receiver Antenna Data. 6. Next Steps.

  9. Executive Functions as Endophenotypes in ADHD: Evidence from the Cambridge Neuropsychological Test Battery (CANTAB)

    Science.gov (United States)

    Gau, Susan Shur-Fen; Shang, Chi-Yung

    2010-01-01

    Background: Little is known about executive functions among unaffected siblings of children with attention deficit/hyperactivity disorder (ADHD), and there is lack of such information from non-Western countries. We examined verbal and nonverbal executive functions in adolescents with ADHD, unaffected siblings and controls to test whether executive…

  10. International Symposium on Wind Energy Systems, Held at Cambridge University, on 7-9 September 1976

    Science.gov (United States)

    1976-12-07

    Darrieus turbine design. B.F. Blackwell, Sandia Laboratories, USA. Some design aspects of high-speed vertical- axis wind turbines . R.J. Templin and P...Energy, Energy Conversion, Power Systems, Windmills, Wind Turbines . 20. §6PAT(Cin~hW. "" aid. it 00e096 suf id""App hr 6Řb nwe) This report of qs brief...large wind turbines ocerating in lare arrays, and the output (with and without storage) of several such arrwef awhen geographically dispersed, has yet to

  11. Biotechnology Conference: Diagnostics 󈨛 Held in Cambridge, England on 10 and 11 December 1987.

    Science.gov (United States)

    1988-05-25

    instrumentation *such as applications in horticulture , agriculture and stable color end-point veterinary practise. Markdt forces responsible for this...and to evaulate the effectiveness of newly fixed with appropriate reagent. The DNA probe, which developed therapeutic treatments. has already been

  12. Dogancan Özsel (ed. Reflections on Conservatism (Newcastle: Cambridge Scholars Publishing, 2011

    Directory of Open Access Journals (Sweden)

    Garrett Barden

    2012-03-01

    Full Text Available In the foreword to his The Ancien Régime and the Revolution (1856 Alexis de Tocqueville wrote that “No nation had ever before embarked on so resolute an attempt as that of the French in 1789 to break with the past, to make, as it were, a scission in their life line and to create an unbridgeable gulf between all they had hitherto been and all they now aspired to be. ...in a word, they spared no pains in their endeavour to obliterate their former selves.”

  13. In search of low cost titanium: the Fray Farthing Chen (FFC) Cambridge process

    CSIR Research Space (South Africa)

    Oosthuizen, SJ

    2010-10-01

    Full Text Available delivering a sponge product, aimed at replacing Kroll sponge alone, does not have potential for large reduction in overall titanium cost. Significant cost savings can only be achieved by also reducing the large number of process steps required to process... the sponge to mill product, including sponge purification, comminution, electrode forming, Vacuum Arc Re-melting, Hot and cold rolling. Presently, economy of scale in the production of titanium dictates that it is most cost effective to cast the largest...

  14. In search of low cost titanium: the fray farthing chen (FFC) cambridge process

    CSIR Research Space (South Africa)

    Oosthuizen, SJ

    2011-03-01

    Full Text Available delivering a sponge product, aimed at replacing Kroll sponge alone, does not have potential for large reduction in overall titanium cost. Significant cost savings can be achieved only by also reducing the large number of process steps required... to process the sponge to mill product, including sponge purification, comminution, electrode forming, vacuum arc re-melting, and hot and cold rolling. Presently, economy of scale in the production of titanium dictates that it is most cost...

  15. Address by William J. Bennett, United States Secretary of Education. (Harvard University, Cambridge, Massachusetts).

    Science.gov (United States)

    Bennett, William J.

    The extent to which U.S. colleges and universities contribute to the fulfillment of students' lives is discussed by Secretary of Education William Bennett in an address to Harvard University. Secretary Bennett's observations are based on his experiences as a law student, freshman proctor, and tutor at Harvard University, as well as his subsequent…

  16. Cambridge Healthtech Institute's 5th Annual Conference: impact of genomics on medicine.

    Science.gov (United States)

    Zanders, E D

    2001-08-01

    The recent publications in Nature and Science by the Human Genome Consortium and Celera Genomics, respectively, while being landmark achievements in themselves, have also given pause for thought. A definitive catalogue of human genes is still not available but the broad picture of how humans compare with lower organisms at the genomic level is becoming clearer. The full impact of these findings on the practice of medicine is hard to predict, but research being conducted now, in the early years of the 21st century, will form the basis of future advances in the diagnosis and treatment of disease. Exactly what this will entail is the subject of intense debate, but there are some common starting points that were discussed at this meeting in Munich. The main theme to emerge was the need to move beyond the human genome sequence towards an understanding of proteins and their interactions in complex biological pathways, thereby increasing opportunities for drug discovery through the identification of new targets. The majority of the talks were therefore devoted to the description of technological advances in the analysis of gene and protein expression (and interaction) and in the use of various methods of gene deletion in order to validate individual proteins as drug targets. Perhaps it will still be a few years before it will be possible to report on the application of genomic analyses to routine medical practice at the first point of care for patients but when that happens, the research efforts described here will have been worthwhile.

  17. Ingestion of phosphorus-32 at Massachusetts Institute of Technology, Cambridge, Massachusetts, identified on August 19, 1995

    International Nuclear Information System (INIS)

    1995-12-01

    On Monday, October 16, 1995, the Massachussetts Institue of Technology (MIT, the licensee) notified the US Nuclear Regulatory Commission (NRC) of an incident involving ingestion of phosphorus-32 by a researcher at the MIT Center for Cancer Research. The licensee informed the NRC that a researcher had reported the incident on August 19. The licensee initially estimated the intake as 500 microcuries (19 MBq) and the dose as 4000 millirem (40 mSv) to the individual. On October 12, the licensee informed the researcher that its final intake estimate was 579 microcuries (21 MBq), just under the 600 microcuries (22 MBq) which would represent an overexposure. On October 17, the NRC established an Incident Investigation Team to investigate the case. NRC also contracted with Lawrence Livermore National Laboratory and Oak Ridge Institute for Science and Education to do independent dose assessments of the urine sample data and the whole-body data. The Team concluded that the licensee's final intake and dose estimates were in accordance with accepted scientific references and NRC guidance. However, recognizing the uncertainties involved in the use of models to simulate human characteristics, the Team determined the intake would be better characterized as likely falling within a range of 500 to 750 microcuries (19--28 NMq). An NRC medical consultant concluded that no symptoms or acute effects should be observed from an intake of this level

  18. [Experimental Course in Elementary Number Theory, Cambridge Conference on School Mathematics Feasibility Study No. 35.

    Science.gov (United States)

    Hatch, Mary Jacqueline

    In the winter of 1965, an experimental course in Elementary Number Theory was presented to a 6th grade class in the Hosmer School, Watertown, Massachusetts. Prior to the introduction of the present material, students had been exposed in class to such topics from the University of Illinois Arithmetic Project as lattices, number lines, frame…

  19. Averages, Areas and Volumes; Cambridge Conference on School Mathematics Feasibility Study No. 45.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    Presented is an elementary approach to areas, columns and other mathematical concepts usually treated in calculus. The approach is based on the idea of average and this concept is utilized throughout the report. In the beginning the average (arithmetic mean) of a set of numbers is considered and two properties of the average which often simplify…

  20. GOALS FOR SCHOOL MATHEMATICS, THE REPORT OF THE CONFERENCE ON SCHOOL MATHEMATICS (CAMBRIDGE, MASSACHUSETTS, 1963).

    Science.gov (United States)

    Educational Services, Inc., Watertown, MA.

    REPORTED ARE THE TENTATIVE VIEWS OF A GROUP OF MATHEMATICIANS ON THE CONTENT OF A PRE-COLLEGE MATHEMATICS CURRICULUM THAT MIGHT CONCEIVABLY REPRESENT THE TYPE OF PROGRAM WHICH WILL BE OPERATING IN A FEW DECADES. THE COMMITTEE PRESENTS ITS VIEWS, NOT AS A CURRICULUM GUIDE FOR ADMINISTRATORS AND MATHEMATICS EDUCATORS, BUT AS A BASIS FOR DISCUSSION,…

  1. Progress Report for March, 1964; Cambridge Conference on School Mathematics; Feasibility Study No. 33.

    Science.gov (United States)

    Lomon, Earle

    This report gives information regarding the mathematical classroom activities for the first six grades at Estabrook School from March 1964 to June 1965. A brief progress report is given regarding the instruction provided to teach such concepts as addition and subtraction, symmetry transformations of squares, open sentences and graphing,…

  2. Linear Elastic Waves - Series: Cambridge Texts in Applied Mathematics (No. 26)

    Science.gov (United States)

    Harris, John G.

    2001-10-01

    Wave propagation and scattering are among the most fundamental processes that we use to comprehend the world around us. While these processes are often very complex, one way to begin to understand them is to study wave propagation in the linear approximation. This is a book describing such propagation using, as a context, the equations of elasticity. Two unifying themes are used. The first is that an understanding of plane wave interactions is fundamental to understanding more complex wave interactions. The second is that waves are best understood in an asymptotic approximation where they are free of the complications of their excitation and are governed primarily by their propagation environments. The topics covered include reflection, refraction, the propagation of interfacial waves, integral representations, radiation and diffraction, and propagation in closed and open waveguides. Linear Elastic Waves is an advanced level textbook directed at applied mathematicians, seismologists, and engineers. Aimed at beginning graduate students Includes examples and exercises Has application in a wide range of disciplines

  3. Statistical Mechanics of Disordered Systems - Series: Cambridge Series in Statistical and Probabilistic Mathematics (No. 18)

    Science.gov (United States)

    Bovier, Anton

    2006-06-01

    Our mathematical understanding of the statistical mechanics of disordered systems is going through a period of stunning progress. This self-contained book is a graduate-level introduction for mathematicians and for physicists interested in the mathematical foundations of the field, and can be used as a textbook for a two-semester course on mathematical statistical mechanics. It assumes only basic knowledge of classical physics and, on the mathematics side, a good working knowledge of graduate-level probability theory. The book starts with a concise introduction to statistical mechanics, proceeds to disordered lattice spin systems, and concludes with a presentation of the latest developments in the mathematical understanding of mean-field spin glass models. In particular, recent progress towards a rigorous understanding of the replica symmetry-breaking solutions of the Sherrington-Kirkpatrick spin glass models, due to Guerra, Aizenman-Sims-Starr and Talagrand, is reviewed in some detail. Comprehensive introduction to an active and fascinating area of research Clear exposition that builds to the state of the art in the mathematics of spin glasses Written by a well-known and active researcher in the field

  4. Developing technology intelligence strategy to access knowledge of innovation clusters. : The case of KODAK in Cambridge

    OpenAIRE

    Dang , Rani Jeanne; Mortara , Letizia; Thomson , Ruth; Minshall , Tim

    2010-01-01

    International audience; Current times are characterised by a knowledge-based economy and fast technological change. In this difficult environment, companies compete to maintain a relevant position through innovation. In response to these challenges, many companies are currently adopting an open approach to innovation, pursuing innovation by combining internal and external resources. Technology intelligence (TI) activities support the implementation of open innovation with the systematic captu...

  5. Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies

    International Nuclear Information System (INIS)

    Bleehen, N.M.

    1980-01-01

    Fifty-five patients with grade 3 and 4 supratentorial astrocytomas, were randomized into a three-limb study. At 9 months after the last treatment there were no differences in survival between the treatment groups. No cases of peripheral neuropathy were seen. Investigations into the possible cause of this are presented. It is thought that microsomal enzyme induction by the anticonvulsants phenobarbitone and phenytoin resulted in increased 0-demethylation of the misonidazole. Clinical data to confirm this view are presented. Current MRC protocols of misonidazole studies on gliomas and carcinomas of the cervix and head and neck are summarized

  6. Ingestion of phosphorus-32 at Massachusetts Institute of Technology, Cambridge, Massachusetts, identified on August 19, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    On Monday, October 16, 1995, the Massachussetts Institue of Technology (MIT, the licensee) notified the US Nuclear Regulatory Commission (NRC) of an incident involving ingestion of phosphorus-32 by a researcher at the MIT Center for Cancer Research. The licensee informed the NRC that a researcher had reported the incident on August 19. The licensee initially estimated the intake as 500 microcuries (19 MBq) and the dose as 4000 millirem (40 mSv) to the individual. On October 12, the licensee informed the researcher that its final intake estimate was 579 microcuries (21 MBq), just under the 600 microcuries (22 MBq) which would represent an overexposure. On October 17, the NRC established an Incident Investigation Team to investigate the case. NRC also contracted with Lawrence Livermore National Laboratory and Oak Ridge Institute for Science and Education to do independent dose assessments of the urine sample data and the whole-body data. The Team concluded that the licensee`s final intake and dose estimates were in accordance with accepted scientific references and NRC guidance. However, recognizing the uncertainties involved in the use of models to simulate human characteristics, the Team determined the intake would be better characterized as likely falling within a range of 500 to 750 microcuries (19--28 NMq). An NRC medical consultant concluded that no symptoms or acute effects should be observed from an intake of this level.

  7. The sound of moving bodies. Ph.D. Thesis - Cambridge Univ.

    Science.gov (United States)

    Brentner, Kenneth Steven

    1990-01-01

    The importance of the quadrupole source term in the Ffowcs, Williams, and Hawkings (FWH) equation was addressed. The quadrupole source contains fundamental components of the complete fluid mechanics problem, which are ignored only at the risk of error. The results made it clear that any application of the acoustic analogy should begin with all of the source terms in the FWH theory. The direct calculation of the acoustic field as part of the complete unsteady fluid mechanics problem using CFD is considered. It was shown that aeroelastic calculation can indeed be made with CFD codes. The results indicate that the acoustic field is the most susceptible component of the computation to numerical error. Therefore, the ability to measure the damping of acoustic waves is absolutely essential both to develop acoustic computations. Essential groundwork for a new approach to the problem of sound generation by moving bodies is presented. This new computational acoustic approach holds the promise of solving many problems hitherto pushed aside.

  8. What Is a Child? Children's Perceptions, the Cambridge Primary Review and Implications for Education

    Science.gov (United States)

    Adams, Kate

    2014-01-01

    Debate about the definition of a "child" occurs in multi-disciplinary contexts, most recently located in the new sociology of childhood where social constructionism is the dominant discourse. Given that the child's voice has become an increasingly valued component of research, this paper reports on one aspect of a study which explored…

  9. Residencia del colegio de Cristo, en Cambridge - Gran Bretaña

    Directory of Open Access Journals (Sweden)

    Denys Lasdun & Partners, Arquitectos

    1973-03-01

    Full Text Available This structure rises by successive terraces, extending from within the existing college onto King's Street but keeping the traditional tone of university isolation from the rest of the city. The main floor contains utility rooms, shops, porter's lodging, sitting rooms, lecture halls, conference rooms, bar, and parking access. The upper floors house the living quarters, i.e. rooms with bath. A reinforced concrete base supports the upper, prefabricated floors.El edificio se levanta —por medio de terrazas sucesivas— desde el colegio existente hasta volar sobre la calle King, recogiendo el tradicional concepto de apertura hacia dentro y aislamiento respecto de la ciudad. La planta baja alberga: - las zonas de instalaciones; - tiendas; - vivienda del conserje; - estancias nobles, tales como salas de lectura, coloquios y bar; - acceso al aparcamiento. En las plantas altas están situadas las habitaciones con baño. La estructura de la planta baja es de hormigón armado y soporta las plantas elevadas, construidas a base de elementos prefabricados.

  10. Integrated optical circuit engineering IV; Proceedings of the Meeting, Cambridge, MA, Sept. 16, 17, 1986

    Science.gov (United States)

    Mentzer, Mark A.; Sriram, S.

    The design and implementation of integrated optical circuits are discussed in reviews and reports. Topics addressed include lithium niobate devices, silicon integrated optics, waveguide phenomena, coupling considerations, processing technology, nonlinear guided-wave optics, integrated optics for fiber systems, and systems considerations and applications. Also included are eight papers and a panel discussion from an SPIE conference on the processing of guided-wave optoelectronic materials (held in Los Angeles, CA, on January 21-22, 1986).

  11. RESENHA DESCRITIVA - Cambridge Handbook of Strategy-as-Practice v.1

    Directory of Open Access Journals (Sweden)

    Marcio Luiz Marietto

    2016-12-01

    Full Text Available Desde o artigo seminal de Whittington (1996 propondo que os estudos em Estratégia Organizacional levassem em consideração a estratégia do ponto de vista sociológico, em detrimento somente ao ponto de vista econômico, a abordagem da Estratégia como Prática (S-as-P, no exterior, parece estar se consolidado. A prova da robustez destes estudos encontra-se no primeiro volume do Handbook de Estratégia como Prática lançado em 2010. O livro, mais do que detalhar estudos passados forneceu (além das direções ontológicas, teóricas e metodológicas perspectivas alternativas para a expansão e o desenvolvimento futuro da área. Todavia, os estudos da S-as-P na América Latina e, em especial, no Brasil parecem, ainda, encontrar dificuldades de compreensão das propostas da abordagem. Desta forma, com o objetivo de contribuir para uma melhor compreensão dos pressupostos ontológicos, teóricos e metodológicos para o aumento da qualidade das futuras pesquisas Brasileiras e Latino Americanas na S-as-P, devido ao alcance internacional da RIAE, optou-se pela realização de uma resenha descritiva, também conhecida como resenha resumo, do conteúdo do Handbook. Para melhor direcionar este objetivo não foi realizada a resenha da última parte (Parte IV do livro. Esta seção mostra exemplos de estudos empíricos realizados na área da S-as-P. Também, existe a intenção futura de se realizar a resenha descritiva do segundo volume do Handbook de Estratégia como Prática publicado em 2015.

  12. Walking and Mapping: Artists as Cartographers. By Karen O’Rourke. Cambridge, MA. MIT Press, 2013.

    Directory of Open Access Journals (Sweden)

    Joel Weishaus

    2014-06-01

    Full Text Available While there is a long well-documented tradition of poets walking and writing about the landscape, for at least the past fifty years visual artists have been laying out walks as various kinds of artwork. More recently, with the technology of mapping morphing into electronic devices, artists have begun using these tools to develop entirely new genres.

  13. BORTONI-Ricardo, Stella M. The urbanization of rural dialect speakers: a sociolinguistic study in Brazil. Cambridge: Cambridge University Press, 1985. 265p. BORTONI-Ricardo, Stella M. The urbanization of rural dialect speakers: a sociolinguistic study in Brazil. Cambridge: Cambridge University Press, 1985. 265p.

    Directory of Open Access Journals (Sweden)

    Maria Jandyra Cunha

    2008-04-01

    Full Text Available Quais são os principais fatores em ação na preservção das variedades linguisticas rurais e/ou não padrão no Brasil? Seria a sua manutenção simplesmente o resultado do analfabetismo ou da marginalização social ou geografica? Os dialetos retrocedem a medida que a população ganha acesso a educação formal? Até que ponto há uma ideologia de prestigio operando entre a chamada população marginal? Até que ponto a tendência homogeneizadora da sociedade urbana oscila entre duas forças contrarias: de um lado as pressões de uma padronização, de outro a manutengao das formas não-padrão como baluartes de identidades grupais?

  14. Air Force Cambridge Research Laboratories Report on Research, July 1972 - June 1974

    Science.gov (United States)

    1975-05-01

    run only during-the.optical and amplitude are both recorded with the observing season - that is, when the sun is GEOPOLE SENSORS VLF GBR Rugby , England...j. S., and SCIIUltji, B1 . D. Mtesospheric Posutive Ion Concentrations, Mobilities an(l hIrared Observations if the Earth’s Upper Atmosphere Loss...Inst. ofI’echnol.) Calif. (17-20 October 1972) and SACKErr, 1). B1 . Vlibration-t’,bration Tratsfer Rate Out ofthue Thi~d M~i.~m, ID., ScinmossuiEi

  15. Das Weibchen von Erigonoplus justus (O. P.-Cambridge, 1875 (Araneae: Linyphiidae

    Directory of Open Access Journals (Sweden)

    Thaler, Konrad

    2001-04-01

    Full Text Available The rare erigonine Erigonoplus justus was recently discovered at a xerothermic site in Rheinland-Pfalz. Its female is described for the first time. The species is new for Germany. Habitat preference, phenology and distribution area of E. justus are briefly discussed.

  16. Validating Score Interpretations and Uses: Messick Lecture, Language Testing Research Colloquium, Cambridge, April 2010

    Science.gov (United States)

    Kane, Michael

    2012-01-01

    The argument-based approach to validation involves two steps; specification of the proposed interpretations and uses of the test scores as an interpretive argument, and the evaluation of the plausibility of the proposed interpretive argument. More ambitious interpretations and uses tend to involve an extended network of inferences and assumptions…

  17. How Do Different Types of Schools Prepare Students for Life at Cambridge?

    Science.gov (United States)

    Perez-Adamson, Clara; Mercer, Neil

    2016-01-01

    Twenty students from different educational backgrounds within the UK were interviewed to investigate how well they considered their secondary school education had prepared them for the educational and social demands of an "elite" university and life within its most traditional colleges. The study asked them how they perceived students…

  18. Art, Science and the Invention of Things That Last

    KAUST Repository

    Edwards, David

    2018-01-14

    Aesthetic creation involves a close collaboration between discovery, invention and cultural exhibition, as well as between learning and producing value. It is typified by the patterns of creative behavior in highly innovative communities like Silicon Valley (for IT) or Boston (for biotech) where cultures of learning, experimentation, and production or commercialization coexist, and where a high degree of interdisciplinary collaboration occurs. In this lecture, David Edwards will highlight the growing movement of aesthetic creation in the arts, sciences and engineering as a path for sustaining and improving the human condition in the longest term. He will highlight aesthetic creation in the light of the culture lab model of Le Laboratoire (Paris, Cambridge) and the new World Frontiers Forum with examples of learning, pubic experimentation and value creation particularly related to the future of sensory experience.

  19. Where to implement local biotech innovations? A framework for multi-scale socio-economic and environmental impact assessment of Green Bio-Refineries

    DEFF Research Database (Denmark)

    Cong, Ronggang; Stefaniak, Irena; Madsen, Bjarne

    2017-01-01

    Green Bio-Refineries (GBRs) have economic and environmental potentials through changing land use from cereals to grass production and provision of grass-based protein feed for livestock production and other valuable byproducts. However, the potentials are dependent on local conditions of the GBRs...

  20. Current barriers, challenges and opportunities for the development of effective STI vaccines: point of view of vaccine producers, biotech companies and funding agencies.

    Science.gov (United States)

    Dodet, Betty

    2014-03-20

    Several barriers limit the development of vaccines against sexually transmitted diseases (STIs). Critical scientific information is missing that makes the feasibility and the likelihood of success of vaccines against genital herpes, chlamydia, gonorrhea and trichomonas uncertain: the immunity induced by natural infection is absent or imperfect which seriously limits the capacity to define the types of immune responses that an effective vaccine must induce. Reliable animal models are lacking and a number of crucial clinical questions are still unanswered about the goal of these vaccines and definition of endpoints for clinical trials. In the absence of a clear recognition of the need for vaccines against these diseases, there is no motivation for public or private research and industry to invest in the development of vaccines against STIs. The STI burden should be evaluated not only in terms of mortality and morbidity, but also in terms of economic and psycho-social impact. A global public-private consortium could mobilize the joint efforts of all stakeholders involved in the research, development and implementation of STI vaccines of the public and private sectors; ensure that sufficient resources are applied to R&D of vaccines against these STIs; and provide the pull-push forces that are necessary to overcome the barriers to develop safe and effective vaccines against these diseases. Copyright © 2014. Published by Elsevier Ltd.

  1. Sectoral Innovatiohn Performance in the Biotechnology Sector. Final Report. Task 1

    NARCIS (Netherlands)

    Enzing, C.M.; Valk, T. van der

    2010-01-01

    In general the biotechnology sector can be qualified as a science driven and high tech sector. This applies for both the group of biotech start-ups that are present in each of the three sub-sectors (red biotech: health/pharma, green biotech: agrifood and white biotech: chemicals) as for the red

  2. BOOK REVIEW: Structures in the Universe by Exact Methods: Formation, Evolutions, Interactions (Cambridge Monographs on Mathematical Physics) Structures in the Universe by Exact Methods: Formation, Evolutions, Interactions (Cambridge Monographs on Mathematical Physics)

    Science.gov (United States)

    Coley, Alan

    2010-05-01

    In this book the use of inhomogeneous models in cosmology, both in modelling structure formation and interpreting cosmological observations, is discussed. The authors concentrate on exact solutions, and particularly the Lemaitre-Tolman (LT) and Szekeres models (the important topic of averaging is not discussed). The book serves to demonstrate that inhomogeneous metrics can generate realistic models of cosmic structure formation and nonlinear evolution and shows that general relativity has a lot more to offer to cosmology than just the standard spatially homogeneous FLRW model. I would recommend this book to people working in theoretical cosmology. In the introduction (and in the concluding chapter and throughout the book) a reasonable discussion of the potential problems with the standard FLRW cosmology is presented, and a list of examples illustrating the limitations of standard FLRW cosmology are discussed (including potential problems with perturbation methods). In particular, the authors argue that the assumptions of isotropy and spatial homogeneity (and consequently the Copernican principle) must be properly challenged and revisited. Indeed, it is possible for `good old general relativity' to be used to explain cosmological observations without introducing speculative elements. In part I of the book the necessary background is presented (readers need a background in general relativity theory at an advanced undergraduate or graduate level). There is a good (and easy to read) review of the exact spherically symmetric dust Lemaitre-Tolman model (LT) (often denoted the LTB model) and the Lemaitre and Szekeres models. Light propogation (i.e. null geodesics, for both central and off-center observers) in exact inhomogeneous (LT) models is reviewed. In part II a number of applications of exact inhomogeneous models are presented (taken mainly from the authors' own work). In chapter 4, the evolution of exact inhomogeneous models (primarily the LT model, but also the Szekeres model) is studied regarding structure formation. I thought that the authors describe the advantages and drawbacks of the idealized exact solutions used in the physical modelling in a reasonable manner (although more concise conclusions might have been useful). The authors also address the formation of a galaxy with a central black hole, the formation and evolution of rich galactic clusters and voids and other structures, and the effects of radiation in the models. The most interesting application is presented in chapter 5; namely, the effects of inhomogeneities on observations such as the luminosity distance relation and the explanation of the observed dimming of distant SN Ia (which is usually interpreted within the standard FLRW model in terms of the existence of dark energy). The main conclusion of this work is that data can be reproduced within the LT model (via inhomogeneities in general relativity, but without introducing dark energy). In particular, a number of exact LT solutions were surveyed, and a full discussion of various models in the literature (and a critique of the various assumptions) is presented. In the next chapter the possible resolution of the horizon problem without inflation, in terms of shell crossing in a LT model, is discussed. This is perhaps the most controversial chapter of the book. In the final chapter 7, the influence of inhomogeneous structures in the path of a light ray (for both center and off-center observers in a special Szekeres Swiss cheese model) on the observed temperature distribution of the CMB is discussed. This is a very important topic, but only a heuristic and qualitative study is presented here; more work on the multipole moments of higher order would be necessary for a more comprehensive analysis.

  3. Book Review: Unifying scientific theories: physical concepts and mathematical structures. Margaret Morrison, Cambridge University Press, Cambridge, 2000, pp. 280, US 65.00, ISBN 0-521-65216-2 hardback

    Science.gov (United States)

    Debs, Talel A.

    In addition to being a thorough and timely treatment of unity in science, Morrison's book is particularly noteworthy for the kind of inquiry it represents. In the context of current debates in the history and philosophy of science, Morrison has managed to chart a very persuasive middle path through potentially contentious extreme positions. Also, by taking an approach that is at once conceptual and historical, she has produced a book that truly addresses both the history and philosophy of modern science; it allows the reader to interact with key philosophical questions in addition to well researched and well documented historical accounts. These accounts, which function as case studies, are provided in Chapters 3-6. They are valuable both in-and-of themselves, and as examples which illustrate Morrison's main philosophical thesis.

  4. David Schimmelpenninck van der Oye and Bruce W. Menning, eds., Reforming the Tsar's Army: Military Innovation in Imperial Russia from Peter the Great to the Revolution, Washington, DC: Woodrow Wilson Center and Cambridge: Cambridge UP, 2004.

    Directory of Open Access Journals (Sweden)

    David Stone

    2006-11-01

    Full Text Available David Schimmelpenninck and Bruce Menning have produced an excellent volume collecting contributions of a number of both well-established and junior scholars on the history and development of the tsarist military, grouped together around the general theme of reform. In some ways, it is comparable to Eric Lohr and Marshall Poe's complementary The Military and Society in Russia, 1450-1917 (Leiden, 2002. Schimmelpenninck and Menning's contributors, however, focus more on political and institutio...

  5. The Volpe Center GPS Adjacent Band Compatibility Program Plan : GPS Adjacent Band Compatibility Workshop, Volpe Center, Cambridge MA

    Science.gov (United States)

    2014-09-18

    Approach to DOT GPS Adjacent Band Compatibility Assessment. Identify forums and provide public outreach to make sure the progress and work are as open and transparent as possible. Develop an implementation plan that incorporates aspects from the DOT ...

  6. Collaborative Academic Library Digital Collections Post-Cambridge University Press, HathiTrust and Google Decisions on Fair Use

    Directory of Open Access Journals (Sweden)

    Michelle M. Wu

    2016-09-01

    Full Text Available Academic libraries face numerous stressors as they seek to meet the needs of their users through technological advances while adhering to copyright laws. This paper seeks to explore one specific proposal to balance these interests, the impact of recent decisions on its viability, and the copyright challenges that remain after these decisions

  7. Book Review - V Pogoretskyy, Freedom of Transit and Access to Gas Pipeline Networks Under WTO Law (Cambridge University Press, 2017)

    NARCIS (Netherlands)

    Marhold, Anna

    2017-01-01

    In Freedom of Transit and Access to Pipeline Networks under WTO Law, the author appropriately introduces the topic by stating that energy is featuring increasingly prominently as a topic in international trade law. Indeed, while being a dormant issue in the World Trade Organization (“WTO” forum for

  8. Fiber optic and laser sensors IV; Proceedings of the Meeting, Cambridge, MA, Sept. 22-24, 1986

    Science.gov (United States)

    De Paula, Ramon P. (Editor); Udd, Eric (Editor)

    1987-01-01

    The conference presents papers on industrial uses of fiber optic sensors, point and distributed polarimetric optical fiber sensors, fiber optic electric field sensor technology, micromachined resonant structures, single-mode fibers for sensing applications, and measurement techniques for magnetic field gradient detection. Consideration is also given to electric field meter and temperature measurement techniques for the power industry, the calibration of high-temperature fiber-optic microbend pressure transducers, and interferometric sensors for dc measurands. Other topics include the recognition of colors and collision avoidance in robotics using optical fiber sensors, the loss compensation of intensity-modulating fiber-optic sensors, and an embedded optical fiber strain tensor for composite structure applications.

  9. An Experimental Text in Transformational Geometry; Teachers' Guide; Cambridge Conference on School Mathematics Feasibility Study No. 43b.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    This teachers' guide was written to be used in conjunction with the student text, An Experimental Text in Transformational Geometry. The guide is intended to help teachers who have responsibility for teaching the topics Motions and Transformations in the Plane. Each section commences with a general discussion concerning the major ideas which are…

  10. Steven E. Miller and Dmitri V. Trenin, eds., The Russian Military: Power and Policy, Cambridge, MA: MIT Press, 2004.

    Directory of Open Access Journals (Sweden)

    Mikhail Tsypkin

    2005-10-01

    Full Text Available The Russian military largely went below the radar of Western interest after the disintegration of the Soviet Union.  More than a decade after the creation of the Armed Forces of the Russian Federation, they have become again the object of interest for scholars – this time, both Western and Russian, as demonstrated by the reviewed volume, whose editors assembled a group of extraordinarily knowledgeable experts from Russia and the West.  In his introduction, Steven Miller explains that the purp...

  11. Seeing It through: Advanced Strategies "for" Influencing Education Policy. Education Grantmakers Institute (Cambridge, Massachusetts, May 19-21, 2009)

    Science.gov (United States)

    Mackinnon, Anne

    2009-01-01

    "No education grantmaker can afford to ignore public policy. Local, state and federal policies shape the context in which we work by establishing education standards, allocating resources and setting priorities for people working in education." So begins the report on Grantmakers for Educations' 2005 Grantmakers Institute, Foundation…

  12. Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial.

    Science.gov (United States)

    Simmons, Rebecca K; Echouffo-Tcheugui, Justin B; Sharp, Stephen J; Sargeant, Lincoln A; Williams, Kate M; Prevost, A Toby; Kinmonth, Ann Louise; Wareham, Nicholas J; Griffin, Simon J

    2012-11-17

    The increasing prevalence of type 2 diabetes poses a major public health challenge. Population-based screening and early treatment for type 2 diabetes could reduce this growing burden. However, uncertainty persists around the benefits of screening for type 2 diabetes. We assessed the effect of a population-based stepwise screening programme on mortality. In a pragmatic parallel group, cluster-randomised trial, 33 general practices in eastern England were randomly assigned by the method of minimisation in an unbalanced design to: screening followed by intensive multifactorial treatment for people diagnosed with diabetes (n=15); screening plus routine care of diabetes according to national guidelines (n=13); and a no-screening control group (n=5). The study population consisted of 20,184 individuals aged 40-69 years (mean 58 years), at high risk of prevalent undiagnosed diabetes, on the basis of a previously validated risk score. In screening practices, individuals were invited to a stepwise programme including random capillary blood glucose and glycated haemoglobin (HbA(1c)) tests, a fasting capillary blood glucose test, and a confirmatory oral glucose tolerance test. The primary outcome was all-cause mortality. All participants were flagged for mortality surveillance by the England and Wales Office of National Statistics. Analysis was by intention-to-screen and compared all-cause mortality rates between screening and control groups. This study is registered, number ISRCTN86769081. Of 16,047 high-risk individuals in screening practices, 15,089 (94%) were invited for screening during 2001-06, 11,737 (73%) attended, and 466 (3%) were diagnosed with diabetes. 4137 control individuals were followed up. During 184,057 person-years of follow up (median duration 9·6 years [IQR 8·9-9·9]), there were 1532 deaths in the screening practices and 377 in control practices (mortality hazard ratio [HR] 1·06, 95% CI 0·90-1·25). We noted no significant reduction in cardiovascular (HR 1·02, 95% CI 0·75-1·38), cancer (1·08, 0·90-1·30), or diabetes-related mortality (1·26, 0·75-2·10) associated with invitation to screening. In this large UK sample, screening for type 2 diabetes in patients at increased risk was not associated with a reduction in all-cause, cardiovascular, or diabetes-related mortality within 10 years. The benefits of screening might be smaller than expected and restricted to individuals with detectable disease. Wellcome Trust; UK Medical Research Council; National Health Service research and development support; UK National Institute for Health Research; University of Aarhus, Denmark; Bio-Rad. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Joint Services Electronics Program: Annual Progress Report Number 103, 1 October 1988 - 31 July 1989 (Harvard University, Cambridge, Massachusetts)

    Science.gov (United States)

    1989-07-31

    tion energy. We therefore attempted to perform femtosecond time-resolved Raman * spectroscopy on Si, and other homopolar semiconductors, to probe in real...have started examining integrated sensor/neural network circuitry for use in sensori- motor control systems. In these systems the sig- nals from an...array of sensors (typically tactile or optical sensors) are processed to provide a set of motor commands which execute a sensory-data-dependent action

  14. International Conference on Integrated Optical Circuit Engineering, 1st, Cambridge, MA, October 23-25, 1984, Proceedings

    Science.gov (United States)

    Ostrowsky, D. B.; Sriram, S.

    Aspects of waveguide technology are explored, taking into account waveguide fabrication techniques in GaAs/GaAlAs, the design and fabrication of AlGaAs/GaAs phase couplers for optical integrated circuit applications, ion implanted GaAs integrated optics fabrication technology, a direct writing electron beam lithography based process for the realization of optoelectronic integrated circuits, and advances in the development of semiconductor integrated optical circuits for telecommunications. Other subjects examined are related to optical signal processing, optical switching, and questions of optical bistability and logic. Attention is given to acousto-optic techniques in integrated optics, acousto-optic Bragg diffraction in proton exchanged waveguides, optical threshold logic architectures for hybrid binary/residue processors, integrated optical modulation and switching, all-optic logic devices for waveguide optics, optoelectronic switching, high-speed photodetector switching, and a mechanical optical switch.

  15. Rezension zu: Nicole C. Karafyllis, Gotling Ulshöfer: Sexualized Brains. Cambridge u.a.: MIT Press 2008

    Directory of Open Access Journals (Sweden)

    Sigrid Schmitz

    2009-07-01

    Full Text Available In der Auseinandersetzung um geschlechtliche Normierungen spielt die moderne Hirnforschung eine wirkmächtige und inzwischen disziplinenübergreifende Rolle. Nicole Karafyllis und Gotlind Ulshöfer stellen in diesem Sammelband mit Beiträgen aus Neurowissenschaft, Psychologie, Soziologie, Kulturwissenschaft und Philosophie ein multiperspektivisches Diskursfeld zu der Frage vor, ob die Emotionale Intelligenz (EI als erstrebenswerte Fähigkeit die klassische Kodierung in männliche Rationalität bzw. weibliche Emotionalität dekonstruieren und ein emanzipatorisches Potential entgegen gesellschaftlichen Hierarchisierungen entfalten kann. Viele Aspekte, Verbindungen zwischen den Diskurssträngen und wechselseitige Beeinflussungen, aber auch disziplinäre Eingrenzungen werden sichtbar, die eine kritische Fortführung des hier angestoßenen Dialogs notwendig machen.

  16. H. VAN RIEMSDIJK AND EDWIN WILLIAMS, /ntroduction to the Theory of Grammar, Cambridge. (The MIT Press 1986, xvi + 366 pp.

    Directory of Open Access Journals (Sweden)

    Mario Montalbetti

    1987-06-01

    Full Text Available Con la publicación en 1981 de sus Lectures on Government and Binding (Dordrecht, Foris Noam Chomsky inauguró (al menos editorialmente ya que las ideas se venían discutiendo hacía dos o tres años el nuevo modelo generativo.Este nuevo modelo (denominado GB, las iniciales de los dos procesos aludidos en el título del libro de Chomsky supone un cambio fundamental de enfoques y concepción de la teoría gramatical respecto de los modelos generativos anteriores.

  17. Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: Results from the Cambridge Breast IMRT trial

    International Nuclear Information System (INIS)

    Mukesh, Mukesh B.; Qian, Wendi; Wilkinson, Jennifer S.; Dorling, Leila; Barnett, Gillian C.; Moody, Anne M.; Wilson, Charles; Twyman, Nicola; Burnet, Neil G.; Wishart, Gordon C.; Coles, Charlotte E.

    2014-01-01

    Background: The use of intensity-modulated radiotherapy (IMRT) in breast cancer reduces clinician-assessed breast tissue toxicity including fibrosis, telangectasia and sub-optimal cosmesis. Patient reported outcome measures (PROMs) are also important as they provide the patient’s perspective. This longitudinal study reports on (a) the effect of forward planned field-in-field IMRT (∼simple IMRT) on PROMs compared to standard RT at 5 years after RT, (b) factors affecting PROMs at 5 years after RT and (c) the trend of PROMs over 5 years of follow up. Methods: PROMs were assessed at baseline (pre-RT), 6, 24 and 60 months after completion of RT using global health (EORTC QLQ C30) and 4 breast symptom questions (BR23). Also, 4 breast RT-specific questions were included at 6, 24 and 60 months: change in skin appearance, firmness to touch, reduction in breast size and overall change in breast appearance since RT. The benefits of simple IMRT over standard RT at 5 years after RT were assessed using standard t-test for global health and logistic regression analysis for breast symptom questions and breast RT-specific questions. Clinical factors affecting PROMs at 5 years were investigated using a multivariate analysis. A repeated mixed model was applied to explore the trend over time for each of PROMs. Results: (89%) 727/815, 84%, 81% and 61% patients completed questionnaires at baseline, 6, 24 and 60 months respectively. Patients reported worse toxicity for all four BR23 breast symptoms at 6 months, which then improved over time (p < 0.0001). They also reported improvement in skin appearance and breast hardness over time (p < 0.0001), with no significant change for breast shrinkage (p = 0.47) and overall breast appearance (p = 0.13). At 5 years, PROMs assessments did not demonstrate a benefit for simple IMRT over standard radiotherapy. Large breast volume, young age, baseline surgical cosmesis and post-operative infection were the most important variables to affect PROMs. Conclusions: This study was unable to demonstrate the benefits of IMRT on PROMs at 5 years. PROMs are influenced by non-radiotherapy factors and surgical factors should be optimised to improve patients’ outcome. Only a small proportion of patients report moderate–severe breast changes post radiotherapy, with most PROMs improving over time. The difference in clinician assessment and PROMs outcome requires further investigation

  18. Proceedings of the Image Understanding Workshop (18th) Held in Cambridge, Massachusetts on 6-8 April 1988. Volume 1

    Science.gov (United States)

    1988-04-01

    types of image information, the Hough transform, and ( BPP ) was upgraded with the floating point platform texture modeling [Aloimonos et al. 1987...Aloimonos , kit, to provide much faster scientific computation. Our and Swain 1987a; 1987b; Bandopadhay 1986; 3-node BPP was upgraded to a Butterfly PlusO...September, 1976. There are many avenues for future work. First and foremost we [2) Fau , P., and Hanson, A.J. n hp are investigating the use of an

  19. Book Review, Ethics and the Media: An Introduction, by Stephen J. A. Ward (Cambridge U Press, 2011)

    DEFF Research Database (Denmark)

    Ess, Charles

    2013-01-01

    I highlight important elements of the volume, its context in digital ethics more broadly, and contributions to both journalism ethics as such and digital ethics as an emerging field.......I highlight important elements of the volume, its context in digital ethics more broadly, and contributions to both journalism ethics as such and digital ethics as an emerging field....

  20. Applications of GIS for highway safety : peer exchange summary report, Cambridge, MA, September 14-15, 2011

    Science.gov (United States)

    2011-09-30

    On September 14-15, 2011, the FHWA's Office of Planning and its Office of Safety sponsored a 1.5-day peer exchange to promote the use of GIS and mapping for highway safety applications. This report offers overviews of the presentations given at the p...

  1. Metamorphoses of Visualisation: Experiences of Interpreting Stained-Glass Artworks of Anglican Emmanuel College Chapel of Cambridge University

    Science.gov (United States)

    Sofronova, Lidia V.; Chugunova, Tatiana G.; Khazina, Anna V.; Babayeva, Anastasiya V.; Shmeleva, Natalia V.

    2016-01-01

    This research was caused by an accidental discovery of a photo reproduction of one unknown in Russia masterpiece of British stained glass art of the Victorian age found on open spaces of the Internet: a full-height portrait of John Colet, a famous member of clergy of the pre-reform period, Erasmus' and Thomas More's friend and mentor. Exquisite…

  2. Highlights from the Faraday Discussion on Ionic Liquids: From Fundamental Properties to Practical Applications, Cambridge, UK, September 2017.

    Science.gov (United States)

    Aldous, Leigh; Bendova, Magdalena; Gonzalez-Miquel, Maria; Swadźba-Kwaśny, Małgorzata

    2018-05-22

    For the third time, a Faraday Discussion addressed ionic liquids. Encompassing the wealth of research in this field, the contributions ranged from fundamental insights to the diverse applications of ionic liquids. Lively discussions initiated in the lecture hall and during poster sessions then seamlessly continued during the social program.

  3. Catching the Wave. Summary of discussions during workshop in Cambridge 9th and 10th February 2009

    International Nuclear Information System (INIS)

    Neuhoff, K.; Lester, S.; Laing, T.; Cust, J.; De Coninck, H.C.

    2009-03-01

    Domestic action will be the key to shift developing countries onto low-carbon development trajectories. At the workshop in February 2009 we identified three sets of open questions that have emerged in the international discussion on climate cooperation with developing countries. (A) International support for domestic action and enabling environments. Technology action plans, sustainable development policies and measures and nationally appropriate mitigation actions (NAMAs) are all concepts that rely on domestic policies and actions to shift economies on a low-carbon growth path. We are interested to better understand what are the domestic barriers and drivers for such actions, how international support could unlock some of the domestic discussions, and what type of support would be helpful in the specific circumstances of a country and sector. (B) Indicators to manage implementation of domestic action. While theoretical analysis and initial concepts for policies are often promising, their successful implementation repeatedly turned out to be more challenging. Experience in recent years points to the value of intermediate indicators to monitor, quantify and manage the implementation, to learn from comparison with other countries, and to make governments accountable for their actions or inactions. We are interested to explore the specific indicators that could support the implementation of policies with climate co-benefits, and discuss with stakeholders criteria for their evaluation, and to find categories to allow for the use of such indicators under UNFCCC reporting frameworks. (C) International technology cooperation as basis for domestic action. New technologies and the adoption of technologies from other countries and sectors play a central role in many decarbonisation strategies. This has been recognised and is reflected in a variety of proposals for international technology cooperation. We will explore frameworks to categorise the proposed mechanisms; although such an analysis will focus on a limited number of mechanisms, this should be sufficient to address the needs of different countries, sectors and technologies. A repeated feature of programs to enhance technology innovation, adoption and use is the concept of a conducive environment (enabling environment), that requires domestic action and points to the interactions between international support for domestic action and international technology cooperation. This report summarises some of the ideas that have emerged in the discussion, and provides the basis for research that will be pursued in the coming months

  4. Assessment of Biotechnology Policies and International Trade in Key Markets for U.S. Agriculture

    OpenAIRE

    Marchant, Mary A.; Song, Baohui

    2005-01-01

    The United States leads the world in agricultural biotechnology research, adoption, commercialization, and exports. Our biotech commodities are highly dependent on international markets. Thus, any biotech policy changes by key importing countries may affect U.S. agricultural biotech product exports. This article identifies key markets for U.S. agricultural exports including biotech commodities and discusses current and proposed biotech policies in key markets for U.S. agricultural exports foc...

  5. Religious Experience and Lay Society in T’ang China: A Reading of Tai Fu’s Kuang-i chi, by Glen Dudbridge. Cambridge Studies in Chinese History, Literature and Institutions. Cambridge: Cambridge University Press, 1995. ix+256 pp. Maps. ISBN: 0521482232

    Directory of Open Access Journals (Sweden)

    Amelia Ying Qin

    2014-07-01

    Full Text Available Drawing upon his knowledge and understanding of literature, book culture, and vernacular culture of pre-modern China, Glen Dudbridge offers, in his unique reading of Kuang-i chi 廣異記 (The great book of marvels, insights into the religious experiences of lay society individuals of eighth century China. However, an inquisitive reader must ask the following questions: Can Kuang-i chi, a medieval collection of tales of encounters with the other world by the minor T’ang Dynasty official Tai Fu 戴孚 (fl. 760-780, chin-shih 757, be used for the purpose of the study of religious culture? How? and to what extent? What approaches would be effective in inquiring such a text and what kinds of conclusions can be drawn? Though not explicitly setting forth these questions, Dudbridge’s work serves as answers to them through explicitly defining the nature of Kuang-i chi to his study, discarding conventional categories and establishing new ones in his analysis, and associating Kuang-i chi to the “vernacular,” instead of official, or “centralized,” religious culture (p.63-4. Using a sharp historical focus on the collection, Dudbridge concentrates on the dynamics of change in religious practices of T’ang Dynasty that is rooted and reflected in such a vernacular religious culture....

  6. Create a translational medicine knowledge repository--research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech companies: how will they avoid relearning old lessons?

    Science.gov (United States)

    Littman, Bruce H; Marincola, Francesco M

    2011-05-10

    Pharmaceutical industry consolidation and overall research downsizing threatens the ability of companies to benefit from their previous investments in translational research as key leaders with the most knowledge of the successful use of biomarkers and translational pharmacology models are laid off or accept their severance packages. Two recently published books may help to preserve this type of knowledge but much of this type of information is not in the public domain. Here we propose the creation of a translational medicine knowledge repository where companies can submit their translational research data and access similar data from other companies in a precompetitive environment. This searchable repository would become an invaluable resource for translational scientists and drug developers that could speed and reduce the cost of new drug development.

  7. Create a translational medicine knowledge repository - Research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech companies: how will they avoid relearning old lessons?

    Directory of Open Access Journals (Sweden)

    Marincola Francesco M

    2011-05-01

    Full Text Available Abstract Pharmaceutical industry consolidation and overall research downsizing threatens the ability of companies to benefit from their previous investments in translational research as key leaders with the most knowledge of the successful use of biomarkers and translational pharmacology models are laid off or accept their severance packages. Two recently published books may help to preserve this type of knowledge but much of this type of information is not in the public domain. Here we propose the creation of a translational medicine knowledge repository where companies can submit their translational research data and access similar data from other companies in a precompetitive environment. This searchable repository would become an invaluable resource for translational scientists and drug developers that could speed and reduce the cost of new drug development.

  8. Educational Implications of Psychopathology for Brain-Injured Children; Lesley College Annual Graduate Symposium (3rd, Cambridge, Massachusetts, May 13, 1967).

    Science.gov (United States)

    Gertz, Boris, Ed.

    The symposium report includes the text of an illustrated lecture given by William M. Cruickshank on "Psychopathology and Implications for Educating Brain-Injured Children." Considered in the lecture are hyperactivity, the needs of hyperative children, and educational setting and curriculum. Panel reactions are provided by E.F. Rabe, a pediatric…

  9. [Rets. rmt. : Stefan Halper, Jonathan Clarke. America Alone : The Neo-Conservatives and the Global Order. Cambridge 2004] / Maria Mälksoo

    Index Scriptorium Estoniae

    Mälksoo, Maria, 1979-

    2005-01-01

    Traditsiooniliste konservatiivide S. Halperi ja J. Clarki raamat harutab lahti neokonservatiivse ilmavaate, selle liikumise kujunemise ja mõjuvõimu laienemise ning näitavad, kuidas uuskonservatiivid võtsid võimu USA Riigidepartemangus ja Pentagonis

  10. Book review of Capital in the Twenty-First Century, by Thomas Piketty. Cambridge, Massachusetts, London, England: The Belknap Press of Harvard Press, 2014, 605 pages

    OpenAIRE

    Paul Dobrescu; Mălina Ciocea

    2015-01-01

    “Every now and then, the field of economics produces an important book; this is one of them” (Cowen, 2014). These are the opening words of Tyler Cowen’s presentation of Thomas Piketty’s work, “Capital in the Twenty-First Century” (Piketty, 2014), in Foreign Affairs. This is a book that is visibly placed in all important bookstores around the world, widely debated, acclaimed, sold (over 1 million copies have been sold so far). It has been favorably reviewed or quoted in all major journals. The...

  11. Book review of Capital in the Twenty-First Century, by Thomas Piketty. Cambridge, Massachusetts, London, England: The Belknap Press of Harvard Press, 2014, 605 pages

    Directory of Open Access Journals (Sweden)

    Paul Dobrescu

    2015-04-01

    Full Text Available “Every now and then, the field of economics produces an important book; this is one of them” (Cowen, 2014. These are the opening words of Tyler Cowen’s presentation of Thomas Piketty’s work, “Capital in the Twenty-First Century” (Piketty, 2014, in Foreign Affairs. This is a book that is visibly placed in all important bookstores around the world, widely debated, acclaimed, sold (over 1 million copies have been sold so far. It has been favorably reviewed or quoted in all major journals. The assessment of “Capital in the Twenty-First Century” by Paul Krugman, Nobel Economics Prize Laureate as a “magnificent, sweeping meditation on inequality”, is highly relevant: “This is a book that will change both the way we think about society and the way we do economics” (Krugman, 2014. Finally, Piketty’s book is included in the list of the year’s best books by prestigious journals, such as The Economist, Financial Times, The Washington Post, Observer, The Independent, Daily Telegraph; Financial Times and McKinsey have hailed it as the best book of 2014.

  12. Book Review: Strategy: The Logic of War and Peace rev. and enlarged ed. by Edward N. Luttwak Cambridge, MA: The Belknap Press of Harvard University Press, 2001

    OpenAIRE

    Wirtz, James J.

    2003-01-01

    In the 1980s scholars in the ªelds of history and political science rediscovered the work of Carl von Clausewitz, the Prussian philosopher of war. This renewed interest sparked a brief revival of the study of war and strategy (the latter of which encompasses efforts to exploit war’s dialectic to achieve military and political victory). After relying for decades on operations research to minimize the likelihood of nuclear war by bolstering deterrence—an approach that largely eli...

  13. Task Force on Women, Minorities and the Handicapped in Science and Technology: Executive Session. Report of the Proceedings (Cambridge, Massachusetts, April 8, 1988).

    Science.gov (United States)

    Task Force on Women, Minorities, and the Handicapped in Science and Technology, Washington, DC.

    The Task Force on Women, Minorities, and the Handicapped in Science and Technology was established by the U.S. Congress in Public Law 99-383 with the purpose of developing a long-range plan for broadening participation in science and engineering. Public hearings were held in Albuquerque (New Mexico), Atlanta (Georgia), Baltimore (Maryland), Boston…

  14. Task Force on Women, Minorities and the Handicapped in Science and Technology: Public Hearing. Report of the Proceedings (Cambridge, Massachusetts, April 7, 1988).

    Science.gov (United States)

    Task Force on Women, Minorities, and the Handicapped in Science and Technology, Washington, DC.

    The Task Force on Women, Minorities, and the Handicapped in Science and Technology was established by the U.S. Congress in Public Law 99-383 with the purpose of developing a long-range plan for broadening participation in science and engineering. Public hearings were held in Albuquerque (New Mexico), Atlanta (Georgia), Baltimore (Maryland), Boston…

  15. IECON '87: Industrial applications of control and simulation; Proceedings of the 1987 International Conference on Industrial Electronics, Control, and Instrumentation, Cambridge, MA, Nov. 3, 4, 1987

    Science.gov (United States)

    Hartley, Tom T. (Editor)

    1987-01-01

    Recent advances in control-system design and simulation are discussed in reviews and reports. Among the topics considered are fast algorithms for generating near-optimal binary decision programs, trajectory control of robot manipulators with compensation of load effects via a six-axis force sensor, matrix integrators for real-time simulation, a high-level control language for an autonomous land vehicle, and a practical engineering design method for stable model-reference adaptive systems. Also addressed are the identification and control of flexible-limb robots with unknown loads, adaptive control and robust adaptive control for manipulators with feedforward compensation, adaptive pole-placement controllers with predictive action, variable-structure strategies for motion control, and digital signal-processor-based variable-structure controls.

  16. International Laser Radar Conference (16th) held at the Massachusetts Institute of Technology, Cambridge, Massachusetts on 20-24 July 1992. Part 1

    Science.gov (United States)

    1993-07-24

    The Oscillator Module is an efficient crossed- porro multi-mode resonator . The module passed a lOg sine sweep vibration test. A Faraday isolator...Nd:Yag laser. Unstable resonator optics are used to limit the divergence to ’ " mrad. The emitted energy is 200 mJ per pulse and the laser repetition...align the laser output to the center of the quad detector. The steering of the laser beam is accomplished via a two-axis gimballed turning prism

  17. Black Scientists and Inventors in the United States: 1731-1980. Curriculum Guide: Department of Science, Cambridge Rindge and Latin School.

    Science.gov (United States)

    Walcott, Phyllis B.

    Four units focusing on 16 different Black scientists or inventors who have contributed to American life and research are presented. As part of an interdisciplinary high school science course, the units are designed to help students develop an understanding of and appreciation for the talents of the individuals studied, motivate minority students…

  18. Donatella della Porta, Social Movements in Times of Austerity: Bringing Capitalism Back into Protest Analysis, Cambridge: Polity Press, 2015, 248 pages, ISBN-13: 9780745688589 (hbk

    Directory of Open Access Journals (Sweden)

    Marius Ioan TĂTAR

    2016-11-01

    Full Text Available The global economic crisis had major social and political impact on European societies. The political consequences of the crisis mainly stem from rising unemployment, the freezing or cuts of public sector pay, declining purchasing power, pessimism about future developments and perceptions of bad governance. In this context, a new wave of protest has spread across Europe as a reaction to the austerity measures adopted during the economic crisis. Governments’ inability to deal with the crisis has generated in many places anxiety, which then turned into popular anger. People who have been hard hit by the crisis placed most of the blame with incumbent governments and condemned the corruption and lack of political responsibility of the political class in general.

  19. International Conference on Deformation, Yield and Fracture of Polymers (9th) Held in Cambridge, UK on 11-14 April, 1994. Conference Papers

    Science.gov (United States)

    1994-01-01

    follows through the formation of cavitated shear bands (dilatation bands). A theory of yielding in porous media , first advanced by Berg, and later developed...and polymers that are end-tethered on to a solid surface. We find that there are generally three stages to the approach to the equilibrium, " mushroom ...flexible strip U, = Ud = 0. The load P moves a(1 - cos9) for a peel,’d length a (see fig. 1) so we have, G = dU.t = -ý( _cosO) bda b

  20. Changes in physical activity and modelled cardiovascular risk following diagnosis of diabetes: 1-year results from the ADDITION-Cambridge trial cohort

    NARCIS (Netherlands)

    Barakat, A.; Williams, K.M.; Prevost, A.T.; Kinmonth, A.L.; Wareham, N.J.; Griffin, S.J.; Simmons, R.K.

    2013-01-01

    Aims To describe change in physical activity over 1year and associations with change in cardiovascular disease risk factors in a population with screen-detected Type2 diabetes. Methods Eight hundred and sixty-seven individuals with screen-detected diabetes underwent measurement of self-reported

  1. AA.VV., Musical Networks. Parallel Distributed Perception and Performance, a cura di Niall Griffith e Peter M. Todd, MA: MIT Press, Cambridge, 1999

    Directory of Open Access Journals (Sweden)

    Maurizio Gabrieli

    2013-12-01

    Full Text Available In un periodo in cui le nuove tecnologie stanno trovando una sempre più vasta diffusione nella quasi totalità degli ambiti della produzione e della ricerca musicale, anche il settore dell'analisi musicale sembra essere coinvolto in questo lento ma inesorabile processo. Una delle ricerche più interessanti è quella che ha portato ad utilizzare, per scopi analitici, tecnologie legate alla cosiddetta Intelligenza Artificiale (IA, una disciplina nata verso la fine degli anni Cinquanta con lo scopo di simulare l'intelligenza mediante un sistema computerizzato. In mancanza di una definizione univoca di intelligenza, un primo gruppo di ricercatori del MIT (Massachusetts Institute of Tecnology, diretti da Marvin Minsksy, assunse come paradigma di riferimento l'intelligenza umana e, in una delle ricerche più avanzate nel campo, le cosiddette reti neurali (neural networks.

  2. Sustainable Materials Management (SMM) Web Academy Webinar: Cupertino CA and Cambridge MA: Tips for How Communities Can Successfully Engage Businesses to Divert Food Scraps

    Science.gov (United States)

    This is a webinar page for the Sustainable Management of Materials (SMM) Web Academy webinar titled Let’s WRAP (Wrap Recycling Action Program): Best Practices to Boost Plastic Film Recycling in Your Community

  3. Fundamentals of Tribology; Proceedings of the International Conference on the Fundamentals of Tribology held at The Massachusetts Institute of Technology, Cambridge, MA

    Science.gov (United States)

    1978-06-01

    of mankind is being chal- lenged by the aspirations of people everywhere for higher standards of living in the face of diminishing availability of...natural resources. In order to meet these aspirations without violating the natural bounds of human habitat, we need to use materials and energy...tS/S = -2.50 OsP (7) where as is the isentropic secant compressibility (AV/ VAP ). With these tools, it is easy to put together an expression for the

  4. Neural Networks for Signal Processing 5. Proceedings of the 1995 IEEE Workshop (5th) Held in Cambridge, MA on 31 Aug-2 Sep 95.

    Science.gov (United States)

    1995-01-01

    dlatabase and 40 x 4 patterns from stranger .0 1 ats at.osirom, known person database but is rejectedl by cxthe-n t-he pattecrn is fFa ;s~e!Y -rpelot-ea...Results with edge preservation We used codebooks with 512 entries and coded 4 by 4 pixel subimages, which gave a 0.5625 bpp (bits per pixel) raw bit...algo- rithm. The raw bpp rate for the coding is 0.5625, but some improvement can already be gained if the frequency of occurrence of each codeword is

  5. Review of Andrés Solimano, International Migration in the Age of Crisis and Globalisation. Historical and Recent Experiences, Cambridge University Press, 2010. 223 Pp.

    Directory of Open Access Journals (Sweden)

    Dirina Claudiu – Ciprian

    2015-12-01

    Full Text Available “International Migration in the Age of Crisis and Globalization. Historical and Recent Experiences” represents a work of major interest in the field of migration and globalization. Apparently two concepts that relate one to another, on a background of major population dynamics, the two notions are the two important pillars in what might perfectly be described as a complex analysis of migration, starting from the elements that have initiated it, and culminating with a fine comparison of positive and negative aspects of this phenomenon.

  6. OSA Proceedings of the Topical Meeting on Nonlinear Guided-Wave Phenomena Held in Cambridge, England (United Kingdom) on 2-4 September 1991. Volume 15

    Science.gov (United States)

    1992-05-22

    spatial soliton dynamics in the framwork of equation (I) is reduced to the investigation of a particle of unit mass in a field of effective anharmonic...looses their relative symmetry as seen in Fig. 3 134 / MF4-3 Retaining this higher gain (G=0.2) and increasing the velocity, v= 0.65, conceptually new

  7. Computer Graphics Special Issue on 1992 Symposium on Interactive 3D graphics Held in Cambridge, Massachusetts on 29 March-1 April 1992

    Science.gov (United States)

    1992-01-01

    it * five representations of a desk: 1) a highly detailed desk with ,m ~ ~ ~ ~ Dlla L.._ ’ ,,,e ".. l, faces subdivided along gradients of radiosity , 2...created by our implementation, including timings and polygon using radiosity approaches [9, 61, by summing the counts. contributions of an approximating...and Winget, J. Improving Radiosity Solutions Through the Use of Analytically Determined Form-Factors. Proc. SIGGRAPH 󈨝 Plate 4, illuminated by both

  8. Peptides. Chemistry and Biology: Proceedings of the American Peptide Symposium (12th) Held in Cambridge, Massachusetts on 16-21 June 1991.

    Science.gov (United States)

    1992-01-01

    the aspartimide-containing peptides with aqueous base (0.1 M NH 4OH, I h, 23QC) completely hydrolyzed the aspartimide to yield both the a and...C8, 127.4 and 7-nitro: C5, 130.5: C8 121.8) [4]. The N-acetvl group in each isomer was hydrolyzed (conc. HCI) and each of the free amine was...were transporters of Ca in vesicles made of DMPC, or egg lecithin . The method used in the binding studies was mainly CD which showed substantial

  9. Rediscovering Antiquity: Karl Weber and the Excavation of Herculaneum, Pompeii, and Stabiae, by C.C. Parslow. Cambridge University Press, 1995

    Directory of Open Access Journals (Sweden)

    James E. Snead

    1997-11-01

    Full Text Available Rediscovering Antiquity is an example of the genre of historical writing which seeks to recast the careers of little-known figures who have fallen into obscurity. This is typically intended to move them and their work into the proper "lineage," that is, the select group of ancestral figures from which modern practices are derived. Parslow is interested in the 18th century excavations of the Vesuvian cities, which, he argues, have been misunderstood by historians of archaeology. Indeed, common sources, such as Daniel (1981:55, describe the initial explorations of Pompeii, Herculaneum, and Stabiae, sponsored by the Bourbon kings of Naples as "...treasure hunts and not serious excavations." While the Roman artifacts removed from the sites are credited with spurring interest in antiquity in Enlightenment Europe, modern scholars have until now devoted little attention to the means through which they were recovered.

  10. Modernity and Loss [in:] Flatey John. 2008. Affective mapping. Melancholia and the politics of modernizm, Cambridge, Massachusetts – London Harvard University Press.

    Directory of Open Access Journals (Sweden)

    Johnatan Flatley

    2014-01-01

    Full Text Available The following text is a translation of fragment of Jonathan Flatley’s book Affective Mapping Melancholia and the Politics of Modernism. The suprising claim of Affective Mapping is that dwelling on loss and melancholia is not necessarily depressing. Flatley argues that melancholy can lead people and writers to productively re-map their relationship to the world. Modernism is an accurate portrait of these processes and related consequences.

  11. A Review: R. Baldwin, “The Great Convergence: Information Technology and the New Globalization” (Cambridge: Belknap Press of Harvard University Press, 2016

    Directory of Open Access Journals (Sweden)

    Nicola Montagna

    2017-05-01

    Full Text Available In the introduction of his book, Richard Baldwin ambitiously says that its reading will “change our way to look at globalisation”. While the aim may sound too pretentious and in some respect misplaced, The Great Convergence: Information Technology and the New Globalization is certainly timely. While it is hard to say whether or not globalisation has entered a terminal crisis, it is true that we are witnessing to processes of de-globalisation and relative attempts of national governments to regain some sovreignty. Against the view that globalisation has reached its terminus, this book states that on the contary it is entering a new phase. Its central assertion is that the radical changes in communication technology around 1990s have transformed the nature of globalization, reducing the costs of production and transferring massive north-to-south flows of know-how. What Baldwin calls “New Globalisation” not only has produced a great convergence of profit shares between the most industrialized and some industrializing countries as a consequence of shifting production to the latter, but it also set the basis for a “Third Wave” of globalisation.

  12. Human Immunodeficiency Virus Seroprevalence among Inmates of the Penitentiary Complex of the Region of Campinas, State of São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Neusa Maria Osti

    1999-07-01

    Full Text Available Six hundred and ninety three male inmates from three penitentiaries, two (A and B maximum-security systems and one (C minimum-security facility, located in Campinas, State of São Paulo, Brazil were studied for the presence of human immunodeficiency virus (HIV antibodies, using a cross-sectional design. The search for anti-HIV antibodies in 693 samples of sera collected was carried out by two serological tests: (a the Microparticle enzyme immunoassay-HIV-1 and HIV-2 (MEIA (Abbott Laboratories and (b the Western Blot-HIV-1 (WB (Cambridge Biotech Corporation to confirm positive results with MEIA. Sera reactivity for HIV antibodies was 14.4%. The highest frequency of anti-HIV antibodies was found in the A and B maximum-security prisons: 17% and 21.5%, respectively. In prison C, the frequency of reagents was 10.9%. Seventy three inmates, initially negative in the MEIA test, were checked again five and seven months later. Three of them, all from the maximum-security facilities, became reactive in the MEIA test, with confirmation in the WB, suggesting that serological conversion had occurred after imprisonment.

  13. Book Review: Conceptual mathematics: a first introduction to categories. F. William Lawvere and Stephen H. Schanuel, Cambridge University Press, Cambridge, 1997 (reprinted with corrections 1998), xvi+358 pp., index, hbk, ISBN 0-521-47249-0, pbk, ISBN 0-521-47817-0

    Science.gov (United States)

    Corfield, David

    Casting scientific or mathematical research activity in the form of programmes with a view to gauging its progressiveness is no straightforward business, as Imre Lakatos discovered. The category theory "programme", now over half a century old, has certainly become too large to be judged as a united enterprise whose members share a common mission. Speaking about Bayesian statistics, Edwin Jaynes could imagine a time when its methods had become so pervasive that its practitioners found their common interests insufficiently extensive to cause them to gather together for conferences, just as the time when researchers could meet up to discuss the uses of Fourier transforms is long past. Well, category theory has already progressed a certain way towards this stage. Its penetration into the various branches of mathematics has been uneven, but in some cases it has been profound. For instance, any algebraic topologist or algebraic geometer just must use a considerable amount of category theory as part of their job. It has also made inroads into logic and, from there, to theoretical computer science (see e.g., Taylor, 1999). Its reach even extends to mathematical physics where, for example, we find topological quantum field theories defined in terms of functors between categories (Atiyah, 1988), and the intriguing prospect that higher-dimensional categories will feature in subsequent developments.

  14. The challenges and future of oral drug delivery: An interview with David Brayden.

    Science.gov (United States)

    Brayden, David J

    2016-12-01

    David Brayden speaks to Hannah Makin, Commissioning Editor: David Brayden is a Full Professor (Advanced Drug Delivery) at the School of Veterinary Medicine, University College Dublin (UCD) and also a Fellow of the UCD Conway Institute. Following a PhD in Pharmacology at the University of Cambridge, UK (1989), and a postdoctoral research fellowship at Stanford University, CA, USA, he set up Elan Biotechnology Research's in vitro pharmacology laboratory in Dublin (1991). At Elan, he became a senior scientist and project manager of several of Elan's joint-venture drug delivery research collaborations with US biotech companies. In 2001, he joined UCD as a lecturer in veterinary pharmacology and was appointed Associate Professor in 2006 and Full Professor in 2014. He was a Director of the Science Foundation Ireland Research Cluster (The Irish Drug Delivery Research Network) from 2007 to 2013, is a Deputy Coordinator of an FP7 Consortium on oral peptides in nanoparticles ('TRANS-INT', 2012-2017), and is a Co-Principal Investigator in 'CURAM', Science Foundation Ireland's new Centre for Medical Devices (2014-2020 [ 1 ]). He was made a Fellow of the Controlled Release Society in 2012. He is the author or co-author of >200 research publications and patents. D Brayden serves on the Editorial Advisory Boards of Drug Discovery Today, European Journal of Pharmaceutical Sciences, Advanced Drug Delivery Reviews and the Journal of Veterinary Pharmacology and Therapeutics, and is an Associate Editor of Therapeutic Delivery. D Brayden works as an independent consultant for drug delivery companies.

  15. Innovative Tools for Scientific and Technological Education in Italian Secondary Schools

    Science.gov (United States)

    Santucci, Annalisa; Mini, Roberta; Ferro, Elisa; Martelli, Paola; Trabalzini, Lorenza

    2004-01-01

    This paper describes the project "Biotech a Scuola" ("Biotech at School"), financed by the Italian Ministry of Education within the SeT program (Special Project for Scientific-Technological Education). The project involved the University of Siena, five senior and junior secondary schools in the Siena area, and a private…

  16. Valuation in life sciences: a practical guide

    National Research Council Canada - National Science Library

    Bogdan, Boris; Villiger, Ralph

    2010-01-01

    ... apply valuation methodologies in life sciences. One of the complicating factors is that, compared to other industries, valuation of biotech innovation is much more demanding. The long 10-15-year development and clinical trials process still represents the main risks faced by any biotech company. Added to that is the fact that getting a drug across the regulato...

  17. Book reviews - Catalogue of Meteorites, 5th ed., revised and enlarged, by Monica M. Grady. Cambridge University Press, 2000, 689 pp., US $150.00 (ISBN 0521-66303-2)

    Science.gov (United States)

    Ivanova, Marina A.

    2002-02-01

    The Catalogue of Meteorites has a long tradition and is one of the most important reference publications for meteorite researchers and cosmochemists. The first Guide to the Catalogue of Meteorites was published in 1881 by Lazarus Fletcher, Keeper of Minerals at the British Museum (Natural History), and contained a description of the nature of meteorites and a list of the 361 samples then in the museum's collection. Over the past century, this list was expanded to include more than just the meteorites that were in the possession of the British Museum; an attempt was made to include names, location, and other information on all meteorites known at the time. Thus, the first Catalogue of Meteorites was published in 1923 by G. T. Prior. His successor at the British Museum was Max H. Hey, who published appendixes to Prior's Catalogue, as well as the second and third editions of the Catalogue of Meteoritesin 1953 and 1966. An appendix to the third edition was published in 1977. Traditionally, the Catalogue contained a listing of all the specimens in any of the world's meteorite collections, in museums or otherwise. With the discovery of large numbers of meteorites in Antarctica, starting in 1969, the publishers of the Catalogue encountered some problems, as hundreds-even thousands-of specimens, many of which may be paired, were brought back from Antarctica from the 1970s onward. The fourth edition of the Catalogue, published in 1985 by Andrew Graham, Alex Bevan, and Robert Hutchison, was the first to deal with this sudden inflation of the number of meteorites. Because most of the thousands of Antarctic meteorites (except the obviously more unusual types, such as irons and certain achondrites) had not been studied in any detail, the fourth edition of the Catalogue wisely limited the entries of these meteorites (in some cases, only those with masses larger than 500 g were included in the Catalogue). The fourth edition of the Catalogue was a handsome and handy reference book that provided a quick introduction and a wealth of information (or, often, the only information) on a large number of meteorites.

  18. James L.W. West III, ed. The Cambridge Edition of the Works of F. Scott Fitzgerald : « Trimalchio » : an Early Version of The Great Gatsby.

    Directory of Open Access Journals (Sweden)

    Jean-Loup Bourget

    2006-04-01

    Full Text Available Présenté comme « an early version of The Great Gatsby », “Trimalchio” est une tentative de reconstitution du manuscrit dactylographié envoyé par Fitzgerald à son éditeur, Scribner’s, en octobre 1924. Ce tapuscrit étant perdu, le texte a été établi à partir des épreuves avant correction, elles-mêmes composées à partir du tapuscrit. Il représente donc un stade intermédiaire entre le manuscrit holographe conservé à Princeton (fac-similé publié par les soins de Matthew J. Bruccoli en 1973 et le ...

  19. Proceedings of the International Conference on the Performance of Off-Road Vehicles and Machines (8th). Volume 3. Held at Cambridge England, on August 5-11, 1984.

    Science.gov (United States)

    1984-08-01

    doppe has been made I* appl the thee ad M etlu ia~ Mdie prblm mowvenng rsu *I wM"eqasm then ~ ~ 1 Of cotP MnUMb~ wn Wi pbusha u iutoW i essity ii of...to that iepoee byth vsicle on the soil. in Mhe vnr lfae of Wei soil It wsIspoeiblo to afply the required swot of mnl paseem ian ring shbar testa bemse...idals plasticiLy. Quart. Appl . Nbtb.. Vol.7. No.4. 411-40. IG 4) Hmahiuchi K. ad H. Umn: Elasto-plastic ontitutive laws of arsomlar iterials. Proc. of

  20. Proceedings of the MIT/ONR (Massachusetts Institute of Technology/Office of Naval Research) Workshop on C3 (Command, Control, and Communications) Systems (6th) Held at Cambridge, Massachusetts on 25-29 July 1983

    Science.gov (United States)

    1983-12-01

    the moment, we are "** This has management implications because within a few months of automating the most recent Sit suggests that we should invest ... fundemental is shown in Fig. 3-2. There is a set of information flow pattern SO-Sl-S2-C2-Cl-CO equations representing the surveillance side is fixed. (Looking... investments , respectivcly, and xi represents We now analyze these three cases separately. the armament level of DMi, i-1,2, which further satisfies "Case

  1. Proceedings of the International Conference on The Performance of Off-Road Vehicles and Machines (8th). Volume 2. Held at Cambridge England, on August 5-11, 1984.

    Science.gov (United States)

    1984-08-01

    soft and slippery ground such as that of paddy fields, the vehicle is often unable to turn smoothly, due to the lack of adequate turning torque...eumv SIndets the lidtlag aeewl slepe me tbe zespeetive slip* 607 elm *.m of the sum ite 12 3 fall 2om silty loin lomw am am sufae Meadow maim mad...covered by grass surfaces, which can be very slippery , and with heavy trailed 7 equipment such as forage harvesting equipment . Slurry tankers introduce

  2. Gene cuisine or Frankenfood? The theory of reasoned action as an audience segmentation strategy for messages about genetically modified foods.

    Science.gov (United States)

    Silk, Kami J; Weiner, Judith; Parrott, Roxanne L

    2005-12-01

    Genetically modified (GM) foods are currently a controversial topic about which the lay public in the United States knows little. Formative research has demonstrated that the lay public is uncertain and concerned about GM foods. This study (N = 858) extends focus group research by using the Theory of Reasoned Action (TRA) to examine attitudes and subjective norms related to GM foods as a theoretical strategy for audience segmentation. A hierarchical cluster analysis revealed four unique audiences based on their attitude and subjective norm toward GM foods (ambivalent-biotech, antibiotech, biotech-normer, and biotech individual). Results are discussed in terms of the theoretical and practical significance for audience segmentation.

  3. The Role of Transgenic Crops in the Future of Global Food and Feed

    OpenAIRE

    O. Škubna; H. Řezbová

    2012-01-01

    The paper is aimed on the problematic of biotech crops planting (GM, transgenic crops). The main aim of this paper is to analyze the trends in the main biotech crops planting groups in the sense of their use for food and feed in the future. The selected groups of biotech crops analyzed in this article are soybeans, maize (corn), cotton and rapeseed (canola). The used methods are chain and basic indexes and regression analysis of times series/ trend data - for predicting on next four years (20...

  4. Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy

    DEFF Research Database (Denmark)

    Strange, Michael Stewart

    2009-01-01

    Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy (Cambridge: Cambridge University Press), 254pp. Udgivelsesdato: 2009......Book Review: John M. Hobson and Leonard Seabrooke (2007) (eds) Everyday Politics of the World Economy (Cambridge: Cambridge University Press), 254pp. Udgivelsesdato: 2009...

  5. Never at rest: a biography of Isaac Newton

    National Research Council Canada - National Science Library

    Westfall, Richard S

    1980-01-01

    ... Paulo, Delhi, Dubai, Tokyo, Mexico City Cambridge University Press 32 Avenue of the Americas, New York, NY 10013-2473, © Cambridge University Press 1980 USA www.cambridge.org Information on this title: www.cambridge.org/9780521231435 This publication is in copyright. Subject to statutory exception and to the provisions of relevant...

  6. Big Data, Small Media

    Directory of Open Access Journals (Sweden)

    Grant Bollmer

    2014-08-01

    Andrew Dubber Radio in the Digital Age Polity, Cambridge, 2013   Charles Ess Digital Media Ethics, Second Edition Polity, Cambridge, 2014   Graeme Kirkpatrick Computer Games and the Social Imaginary Polity, Cambridge, 2013   Dhiraj Murthy Twitter: Social Communication in the Twitter Age Polity, Cambrige, 2013   Jill Walker Rettberg Blogging, Second Edition Polity, Cambridge, 2014

  7. Co-transfer of gfp, CHS and hptII genes into Oncidium Sharry Baby ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-08-04

    Aug 4, 2008 ... 3Malaysian Institute for Nuclear Technology Research (MINT), Bangi, 43000, ... Key words: Biolistic gun, co-transformation, orchidaceae, protocorm-like-body. ... *Corresponding author: E-mail: janna@biotech.upm.edu.my.

  8. Search Results | Page 13 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 121 - 130 of 9175 ... Lessons learned from PAN Asia projects on ICTs in rural areas ... INDIGENOUS POPULATION ETHNIC MINORITIES TRADITIONAL CULTURE FOOD CONSUMPTION DIET NUTRITIVE ... Sharing environmental responsibility in Southeast Mexico ... Indian Biotech Industry and Patent Pooling.

  9. Biodegradation of Polyethylene by Bacillus sp. Indigenous to the ...

    African Journals Online (AJOL)

    Prof. Ogunji

    Nig J. Biotech. Vol. 26 (2013) 68-79 .... determining the formation of new functional groups or disappearance of groups in the polymer ((Milstein et al., 1994). .... This is evident by the various degradation products revealed by the. FTIR spectra.

  10. Democratization of Science and Biotechnological Development ...

    African Journals Online (AJOL)

    sulaiman.adebowale

    Council for the Development of Social Science Research in Africa, 2008 ... tendant ideas of Science Communication and Public Understanding of Biotech- .... human development in the new South Africa – no matter how development.

  11. Search Results | Page 2 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 11 - 20 of 8491 ... India Emerging: The Reality Checks supplies a modern ... Food and Agriculture HERDING VACCINES BIOTECH INDUSTRY ... IDRC funds research that supports gender equality and facilitates women's empowerment.

  12. Eesti teadlaste HIV-vaktsiini süstitakse katseks aafriklastele / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 5. apr., lk. 2. Tartu teadlaste leiutatud ning Soome biotehnoloogiafirma FIT Biotech arendatavat vaktsiini katsetatakse Lõuna-Aafrika Vabariigis 60 surmaviirusega nakatunud inimese peal. Lisa: Eestlaste HIV-vaktsiini senine lugu

  13. Search Results | Page 24 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 231 - 240 of 869 ... Regional patterns and controls of ecosystem salinization with grassland ... Water subsidies from mountains to deserts : their role in sustaining ... biotech firms in developing countries reveals a surprisingly high level of ...

  14. Predicting allergenicity of proteins using Physical–Chemical Property (PCP) motifs

    Science.gov (United States)

    Motivation: Quantitative guidelines to distinguish allergenic proteins from related, but non-allergenic ones are urgently needed for regulatory agencies, biotech companies and physicians. Cataloguing the SDAP database has indicated that allergenic proteins populate a relatively small number of prote...

  15. RET gene mutations and polymorphisms in medullary thyroid ...

    Indian Academy of Sciences (India)

    51 clinically diagnosed MTC patients, 39 family members of patients and 50 normal individuals. The method of .... Documentation system (Amersham Pharmacia Biotech,. Uppsala ... direct nucleotide sequencing to identify the mutations, using.

  16. Active pharmaceutical ingredient (api) from an estuarine fungus, Microdochium nivale (Fr.)

    Digital Repository Service at National Institute of Oceanography (India)

    Bhosale, S.H.; Patil, K.B.; Parameswaran, P.S.; Jagtap, T.G.

    Various marine habitats sustain variety of bio-sources of ecological and biotech potentials. Pharmaceutical potential compound Cyclosporine A was reported from marine fungus Microdochium nivale associated with Porteresia coarctata, a marine salt...

  17. Notes on Commercialization of Biotechnology Research

    DEFF Research Database (Denmark)

    Høy Jakobsen, Palle

    This book introduces aspects of commercialization of biomedical & biotech research including pharmaceutical drug and medical device development, innovation concepts, patent protection & commercialisation of research by securing investments in new companies and by licensing of the commersialisatio...

  18. Experiment list: SRX032893 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Adipocyte Culture || strain=3T3-L1 || cell type=Cultured Adipocytes || chip antibody=PPARgamma || antibody vendor=Santa Cruz Biotech...nology || antibody catalog number=sc-7196X http://dbarch

  19. Experiment list: SRX029315 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available | cell type=CD34+CD133+ hematopoietic progenitor cells (HPCs) || antibody=anti-GABP-alpha || antibody manufacturer=Santa Cruz Biotech...nology http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/e

  20. Ganguly, Dr Nirmal Kumar

    Indian Academy of Sciences (India)

    Date of birth: 11 November 1941. Specialization: Microbiology, Immunology, Biotechnology and Public Health Address: Visiting Professor of Eminence, Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad-Gurgaon Expressway, Faridabad 121 001, Haryana Contact: Office: (011) ...

  1. Estonian science breeds world-class researches / ToivoTänavsuu, Hille Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2010-01-01

    Eesti teadusfirmadest: biotehnoloogia ettevõtted Celecure AS, Protobios OÜ, Icosagen AS, Asper Biotech AS ja Solis BioDyne OÜ, geenitehnoloogia firma Genorama OÜ, keemiatehnoloogia ettevõte AS Cambrex Tallinn

  2. Search Results | Page 51 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 501 - 510 of 9603 ... Lessons learned from PAN Asia projects on ICTs in rural areas ... INDIGENOUS POPULATION ETHNIC MINORITIES TRADITIONAL CULTURE FOOD CONSUMPTION DIET NUTRITIVE ... Sharing environmental responsibility in Southeast Mexico ... Indian Biotech Industry and Patent Pooling.

  3. Brief communication

    Indian Academy of Sciences (India)

    PRAKASH KUMAR

    Keywords. Infection frequency; insects; pests; polymerase chain reaction; Wolbachia ... management of uzifly, a parasitoid of silkworn (Puttaraju and. Prakash 2005a ... supply unit EP S200V/400 mA (Amersham Pharmacia. Biotech USA).

  4. Eestis levinud HIVi erilisus jätab nakatunud vaktsiinilootuseta / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2002-01-01

    Soome biotehnoloogiafirma FIT Biotech on loobumas kavast katsetada Eesti teadlaste leiutatud vaktsiini ka siinsete HIV-positiivsete katserühmal, sest Eestis on levinud maailmas üliharuldane HI-viiruse G-alatüüp

  5. In vivo activities of Baicalin against Chlamydia trachomatis

    African Journals Online (AJOL)

    USER

    2010-03-15

    Rasmussen et al., 1997). The infectivity of the chlamydia was expressed as the number of inclusion forming units. Baicalin (HPLC Content > 98.0%) from Chongqing Green Valley. Bio-tech Co. LTD. (Chongqing, China).

  6. Traditional knowledge and patient protection: conflicting views on ...

    African Journals Online (AJOL)

    ... and biotech companies continue to search for new and better drugs to treat them. ... And yet, even though the importance of these biological resources to global ... as international legal regulations on patent law and traditional knowledge.

  7. Pharmacological effects of two cytolysins isolated from the sea ...

    Indian Academy of Sciences (India)

    Prakash

    2009-12-07

    Email, cebimar@infomed.sld.cu) ... (Amersham Pharmacia Biotech, Uppsala, Sweden) and ionic exchange chromatography on CM-cellulose 52 (Whatman, ... In each well, a fixed concentration of toxin was present at a.

  8. Art, Science and the Invention of Things That Last

    KAUST Repository

    Edwards, David

    2018-01-01

    Silicon Valley (for IT) or Boston (for biotech) where cultures of learning, experimentation, and production or commercialization coexist, and where a high degree of interdisciplinary collaboration occurs. In this lecture, David Edwards will highlight

  9. Isolation and characterization of a new Pseudomonas- related strain ...

    African Journals Online (AJOL)

    SAM

    2014-04-02

    Apr 2, 2014 ... with TIANamp Bacteria DNA DP302 Kit (Beijing Tiangen Biotech) ... Bootstrap analysis was performed 1000 times using the ... MSM media were shown in Figure 1. ..... Publishing Associates/Wiley Interscience, New York.

  10. Adejumo et al., Afr., J. Infect. Dis.

    African Journals Online (AJOL)

    dr adejumo

    1/2 Alere Determine™, Japan 2012) and Uni-Gold™ (Trinity Biotech PLC, Wicklow, Ireland. 2013) were used in parallel algorithm. However, STAT-PAK® was used as tie breaker when there was discordant result. Definition of outcome variable.

  11. Medical Illustration

    Science.gov (United States)

    ... as medical books, journals, magazines, pharma or biotech marketing, films, online video, exhibits, posters, wall charts, educational ... of the health career profession with strong communication skills, medical illustrators work closely with clients to interpret ...

  12. 76 FR 52670 - 2011 Technology Transfer Summit North America Conference

    Science.gov (United States)

    2011-08-23

    ... conference will be further enhanced by the TTS Initiative Business Social Network, an online business... leading universities and research institutes together with biotech & pharma licensing & business... relating to partnering, licensing & business development. Conference speakers for the 2011 include: --Kathy...

  13. NJB VOL.34 Original Lower.cdr

    African Journals Online (AJOL)

    important sources of renewable biological ... The plantain (Musa paradisiaca) and banana chemicals (Nowak et ... fermentable sugars available for bio-ethanol ..... peels. Afr. J. Biochem. Res. 9(9): 104 - 109. 70. Osho et al./ Nig. J. Biotech. Vol.

  14. Experiment list: SRX543048 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea...CID.adh murine thymic lymphoma || development stage=DN3 || chip antibody=rabbit anti-Miz-1 || chip antibody vendor=Santa Cruz Biotech

  15. Between Precautionary Principle and "Sound Science": Distributing the Burdens of Proof

    NARCIS (Netherlands)

    Belt, v.d. H.; Gremmen, B.

    2002-01-01

    Opponents of biotechnology ofteninvoke the Precautionary Principle to advancetheir cause, whereas biotech enthusiasts preferto appeal to ``sound science.'' Publicauthorities are still groping for a usefuldefinition. A crucial issue in this debate isthe distribution of the burden of proof amongthe

  16. Developing South Africa's biomanufacturing industry through a hub for open innovation: Experiences from the Biomanufacturing Industry Development Centre

    CSIR Research Space (South Africa)

    Visser, Daniel F

    2017-10-01

    Full Text Available -Human Moringa fortified foods Sliek Nutrition-Human Lactose free products ConnectMe Speciality chemical Biopolymer Abxtracts Speciality chemical Hydroxytyrosol Biomoringa Agroprocessing Processed moringa leaves/seeds Lighthouse Biotech Probiotics Grapeseed...

  17. Development of carotenoid-enriched vegetables with increased nutritional quality and visual appearance

    Science.gov (United States)

    Carotenoids are a class of red, orange and yellow pigments widely distributed in nature. Biotech approach has been proved to be effective in successfully engineering of carotenoid content in food crops with better health and visual appearance....

  18. SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL ...

    Indian Academy of Sciences (India)

    SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL APPROACH TO EXPLORE UNTAPPED BACTERIAL DIVERSITY. MILIND WATVE; Dept of Microbiology, Abasaheb Garware College, Pune. www.culturematters.org; * Life Research Foundation, Pune; * Evolvus Biotech Pvt. Ltd.,Pune ...

  19. Keeping enzymes kosher

    DEFF Research Database (Denmark)

    Fischer, Johan

    2015-01-01

    Biotech companies increasingly seek certification for compliance with religious and dietary requirements in order to address new consumer markets. Technology plays a crucial role in such inspections alongside centuries old traditions and practices......Biotech companies increasingly seek certification for compliance with religious and dietary requirements in order to address new consumer markets. Technology plays a crucial role in such inspections alongside centuries old traditions and practices...

  20. Greater Philadelphia Bioinformatics Alliance (GPBA) 3rd Annual Retreat 2005

    Science.gov (United States)

    2005-11-01

    Biotech in recent days. The start of Biotech from the Agriculture ie rural side will be discussed and advancement will be discussed in detail towards...such advances in the food and Agricultural aspect. The significant results which not only makes the advancements of the understanding the public but...authored journal publications in human genetics, bioethics for industry and genetics education. Karl V. Steiner, Dr. Ing., Associate Director, Delaware

  1. A CADD-alog of strategies in pharma

    Science.gov (United States)

    Warr, Wendy A.

    2017-03-01

    A special issue on computer-aided drug design (CADD) strategies in pharma discusses how CADD groups in different environments work. Perspectives were collected from authors in 11 organizations: four big pharmaceutical companies, one major biotechnology company, one smaller biotech, one private pharmaceutical company, two contract research organizations (CROs), one university, and one that spans the breadth of big pharmaceutical companies and one smaller biotech.

  2. Editorial: Latest methods and advances in biotechnology.

    Science.gov (United States)

    Lee, Sang Yup; Jungbauer, Alois

    2014-01-01

    The latest "Biotech Methods and Advances" special issue of Biotechnology Journal continues the BTJ tradition of featuring the latest breakthroughs in biotechnology. The special issue is edited by our Editors-in-Chief, Prof. Sang Yup Lee and Prof. Alois Jungbauer and covers a wide array of topics in biotechnology, including the perennial favorite workhorses of the biotech industry, Chinese hamster ovary (CHO) cell and Escherichia coli. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. The technological, economic and institutional aspects behind the development of biotechnology industry in Turku region, Finland

    OpenAIRE

    Viljamaa, Kimmo

    2003-01-01

    This paper examines the recent development of biotechnology related industry in the Finnish city of Turku, where especially pharmaceutical industry has adopted the use of post-1970s molecular biology breakthroughs in ?biotechnology?. Finland is now listed in numbers of biotech firms as the 10th largest in Europe and Turku is the only Finnish city mentioned in the European Commission report among the 20 most significant European biotech centres (2000). The interest of study is to scrutinise th...

  4. Network embeddedness in the internationalization of biotechnology entrepreneurs

    OpenAIRE

    Leppäaho, Tanja; Chetty, Sylvie; Dimitratos, Pavlos

    2018-01-01

    This study investigates how entrepreneurs of biotech enterprises embed in domestic and international networks so as to internationalize. We advance a contextual framework of embeddedness of internationalizing entrepreneurs, providing a contribution (i) by synthesizing and applying existing conceptual insights from the networking literature to provide a more culturally sensitive view of getting embedded for international entrepreneurship in the biotech industry and (ii) by adding insights into...

  5. Syphilis and HIV infections among pregnant women attending antenatal clinics in Republic of Congo.

    Science.gov (United States)

    Niama, Roch Fabien; Loukabou Bongolo, Nadia Claricelle; Bayonne Kombo, Edith Sophie; Yengo, Ruth; Mayengue, Pembe Issamou; Mandingha Kosso, Etoka-Beka; Louzolo, Igor; Macosso, Lucette; Dzeret, Ghislain; Dzabatou Babeaux, Angélie Serge Patrick; Puruehnce, Marie-Francke; Parra, Henri Joseph

    2017-01-01

    HIV and syphilis during pregnancy remain a public health concern especially in developing countries. Pregnant women attending antenatal clinics sites for the first time between September and December 2011 and who accepted to participate in the study were enrolled. The objective was to estimate the syphilis and HIV infection rate in this population. A study was conducted in 44 selected ANCs from 12 departments (5 urban and 7 rural). Pregnant women who accepted to participate in the study, attending selected sentinel ANCs sites for the first time between September and December 2011 were enrolled. To detect HIV antibodies, two consecutive ELISA assays were used (Genscreen Ultra HIV Ag/Ac, (BioRad, France) and Enzygnostic Intergral II (Siemens, GMBH, Marbug-Germany). In case of discordant results, the Western blot test II, HIV1 and 2 (Bio-Rad, Marne la Coquette, France) was used as the reference method. The RPR (Bio-Scan, Karnataka, India) test was performed to detect syphilis infection. The RPR positive results were confirmed using the TPHA test (Biotech, Cambridge, UK). Data were analyzed using SPSS 17.0 software. A total of 2979 pregnant women attending ANCs were enrolled. The global HIV infection rate was estimated to be 3.6% (CI: 95%; 3.0-4.4). As expected, HIV prevalence was significantly higher in women aged above 25 years (4.4% (3.4-5.6), p = 0.026) and those attending urban ANCs (5.04%, p pregnant women (3.92%). The risk for syphilis occurrence was significantly higher among the single women compared to the married ones (4.4% VS 2.7%; p HIV and syphilis coinfection occurred in 22 cases (0.73%). The prevalence's of syphilis and HIV were relatively low. Marital status and sentinel site location were a risk factor associated with HIV and syphilis infections respectively. Therefore, substantial effort is needed to reinforce prevention strategies in this population to prevent mother-to-child and further horizontal transmissions of these infections.

  6. Risk mitigation strategies for viral contamination of biotechnology products: consideration of best practices.

    Science.gov (United States)

    Rosenberg, Amy S; Cherney, Barry; Brorson, Kurt; Clouse, Kathleen; Kozlowski, Steven; Hughes, Patricia; Friedman, Rick

    2011-01-01

    CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December 1-3, 2010 Guest Editors: Arifa Khan (Bethesda, MD), Patricia Hughes (Bethesda, MD) and Michael Wiebe (San Francisco, CA) Viral contamination of biotech product facilities is a potentially devastating manufacturing risk and, unfortunately, is more common than is generally reported or previously appreciated. Although viral contaminants of biotech products are thought to originate principally from biological raw materials, all potential process risks merit evaluation. Limitations to existing methods for virus detection are becoming evident as emerging viruses have contaminated facilities and disrupted supplies of critical products. New technologies, such as broad-based polymerase chain reaction screens for multiple virus types, are increasingly becoming available to detect adventitious viral contamination and thus, mitigate risks to biotech products and processes. Further, the industry embrace of quality risk management that promotes improvements in testing stratagems, enhanced viral inactivation methods for raw materials, implementation and standardization of robust viral clearance procedures, and efforts to learn from both epidemiologic screening of raw material sources and from the experience of other manufacturers with regard to this problem will serve to enhance the safety of biotech products available to patients. Based on this evolving landscape, we propose a set of principles for manufacturers of biotech products: Pillars of Risk Mitigation for Viral Contamination of Biotech Products.

  7. Early Life Histories of Fishes: New Developmental, Ecological and ...

    African Journals Online (AJOL)

    ontogeny and life history models revisited' which is an unabridged .... Hamburg, Germany, in August 1984. The papers are ..... Cambridge University Press, Cambridge, New York and ... lessons to be learnt from the well-illustrated keys and for.

  8. Planktonic algae and cyanoprokaryotes as indicators of ecosystem ...

    African Journals Online (AJOL)

    2013-10-07

    Oct 7, 2013 ... ment favours the presence of this species, as illustrated by its .... water history of Potchefstroom region and the local management of it. ... Cambridge University Press, Cambridge. ... Akademischer Verlag, Jena, Germany.

  9. The Language Policy Practice in Mathematics Education in the ...

    African Journals Online (AJOL)

    kofimereku

    mathematics lesson periods in English at the lower primary level. Efforts to use the native language for meaningful mathematics instructions are constrained by teachers' inability to speak the ..... Cambridge: Cambridge Univ. Press, 9-33.

  10. Status of African baobab (Adansonia digitata) across Gonarezhou ...

    African Journals Online (AJOL)

    MICHAEL HORSFALL

    Tropical Resource Ecology Programme, University of Zimbabwe, P.O. Box MP 167, Mt Pleasant, Harare, Zimbabwe, ... baobab (Adansonia digitata) across Gonarezhou National Park, Zimbabwe. ..... Cambridge University Press, Cambridge.

  11. Status of Lion (Panthera leo) and Spotted Hyena (Crocuta crocuta ...

    African Journals Online (AJOL)

    Bheema

    Wildlife Conservation Research Unit, Zoology, University of Oxford. ... account for the low density of lion and hyena in the park, and perhaps might result in local ..... Carnivore conservation, Cambridge, Cambridge University Press, pp.61–92.

  12. 76 FR 61269 - Protection of Stratospheric Ozone: acceptability Determination 26 for Significant New...

    Science.gov (United States)

    2011-10-04

    .... Miller (eds.)). Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA. This... Park Service, Water Resources Division, Fort Collins, Colorado. \\10\\ Material Safety Data Sheet for 3M...

  13. Short-channel drain current model for asymmetric heavily / lightly ...

    Indian Academy of Sciences (India)

    PRADIPTA DUTTA

    2017-07-29

    Jul 29, 2017 ... (2017) 89:33 ... MS received 25 August 2015; revised 6 March 2017; accepted 6 April 2017; published ..... [18] J P Colinge, J W Park and W Xiong, IEEE Electron. ... devices(Cambridge University Press, Cambridge, 1998).

  14. Unverrichteter Sache

    Directory of Open Access Journals (Sweden)

    Jani Kirov

    2007-01-01

    Full Text Available Rezensiertes Werk: Adriaan Lanni, Law and Justice in the Courts of Classical Athens, Cambridge: Cambridge University Press 2006, 210 S., ISBN-13 978-0-521-85759-8; ISBN-10 0-521-85759-7

  15. Nicht nur böse Christen

    Directory of Open Access Journals (Sweden)

    Andreas Thier

    2003-01-01

    Full Text Available Rezensiertes Werk: John Witte jr., Law and Protestantism. The Legal Teachings of the Lutheran Reformation, New York, Cambridge: Cambridge University Press 2002, XX, 337 S., ISBN 0-521-78132-9

  16. 75 FR 42172 - Agenda and Notice of Partially Closed Meeting of the Recovery Independent Advisory Panel

    Science.gov (United States)

    2010-07-20

    ... Act of 2009, Public Law 111-5 (Recovery Act), and the Federal Advisory Committee Act of 1972 (FACA...: Hyatt Regency Cambridge, 575 Memorial Drive, Cambridge, MA 02139. FOR FURTHER INFORMATION CONTACT: Glen...

  17. Recht autonom

    Directory of Open Access Journals (Sweden)

    Robert von Friedeburg

    2010-01-01

    Full Text Available Rezensiertes Werk: Christopher W. Brooks, Law, Politics and Society in Early Modern England, Cambridge [u. a.]: Cambridge University Press 2008, XII, 456 S., ISBN 978-0-521-32391-8

  18. Eine zu Recht vergessene Vergangenheit?

    Directory of Open Access Journals (Sweden)

    Oliver Lepsius

    2013-01-01

    Full Text Available Review of: David M. Rabban, Law’s History. American Legal Thought and the Transatlantic Turn to History, Cambridge: Cambridge University Press 2013, XVI, 564 S., ISBN 978-0-521-76191-8

  19. Between Despair and Parody

    Directory of Open Access Journals (Sweden)

    Anthony Carty

    2003-01-01

    Full Text Available Review of:Martti Koskenniemi, The Gentle Civilizer of Nations. The Rise and Fall of International Law 1870–1960, Cambridge: Cambridge University Press 2001, xiv, 569 p., ISBN 0-521-6231-11

  20. Fulltext PDF

    Indian Academy of Sciences (India)

    Unknown

    ranging from paleontology (Crônier et al 1998) to developmental biology .... i.e. those that equally integrate different techniques and levels of investigation, are ... P A 1997 Extreme environmental change and evolution (Cambridge: Cambridge.

  1. Stanislav Markus. Property, Predation, and Protection: Piranha Capitalism in Russia and Ukraine

    Directory of Open Access Journals (Sweden)

    Paul Babie

    2016-09-01

    Full Text Available Stanislav Markus. Property, Predation, and Protection: Piranha Capitalism in Russia and Ukraine. Cambridge: Cambridge UP, 2015. xii, 244 pp. Illustrations. Tables. Bibliography. Index. $95.00, cloth.

  2. The practice of teaching mathematics

    OpenAIRE

    Hefendehl-Hebeker, Lisa

    1998-01-01

    The practice of teaching mathematics : experimental conditions of change. - In: The culture of the mathematics classroom / ed. by Falk Seeger .... - Cambridge u.a. : Cambridge Univ. Press, 1998. - S. 104-124

  3. Double-diffusive convection of compressible rotating Walters' (B ...

    African Journals Online (AJOL)

    user

    Mathematical Formulation of the Problem and Perturbation Equations ...... Rayleigh number for the onset of instability via a state of pure oscillations, it suffices to find conditions for which ..... Cambridge University Press, Cambridge, UK.

  4. 77 FR 46120 - Notice of Inventory Completion: Peabody Museum of Archaeology and Ethnology, Harvard University...

    Science.gov (United States)

    2012-08-02

    ... Inventory Completion: Peabody Museum of Archaeology and Ethnology, Harvard University, Cambridge, MA... Museum of Archaeology and Ethnology, Harvard University, Cambridge, MA. The human remains and associated..., Repatriation Coordinator, Peabody Museum of Archaeology and Ethnology, Harvard University, 11 Divinity Avenue...

  5. 75 FR 33328 - Notice of Inventory Completion: Peabody Museum of Archaeology and Ethnology, Harvard University...

    Science.gov (United States)

    2010-06-11

    ... Archaeology and Ethnology, Harvard University, Cambridge, MA; Correction AGENCY: National Park Service..., Harvard University, Cambridge, MA. The human remains and associated funerary objects were removed from... Archaeology and Ethnology, Harvard [[Page 33329

  6. 75 FR 49555 - EPA's Denial of the Petitions To Reconsider the Endangerment and Cause or Contribute Findings for...

    Science.gov (United States)

    2010-08-13

    ... Change 2007. Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA. As discussed in...-mail communications out of context and assert they are ``smoking gun'' evidence of wrongdoing and...

  7. Fatigue crack growth retardation in spot heated mild steel sheet

    Indian Academy of Sciences (India)

    Unknown

    Department of Metallurgical Engineering, *Department of Applied Mechanics and Hydraulics, ... growth retardation increases with increasing level of overload as well as with ..... Suresh S 1996 Fatigue of materials (Cambridge: Cambridge.

  8. Microbiological And Physicochemical Analyses Of Oil Contaminated ...

    African Journals Online (AJOL)

    Michael Horsfall

    mechanic workshops in Benin City metropolis as sole source of carbon and ... collected from the three major mechanic workshops at Igun, Evbareke and ..... safe and acceptable level. ... Cambridge University Press, Cambridge, England.

  9. Kant's Theory of virtue

    DEFF Research Database (Denmark)

    Nielsen, Carsten Fogh

    2012-01-01

    Anmeldelse af Anne Margaret Baxleys bog: "Kant's Thery of Virtue. The Value of Autocracy" (Cambridge University Press, 2010)......Anmeldelse af Anne Margaret Baxleys bog: "Kant's Thery of Virtue. The Value of Autocracy" (Cambridge University Press, 2010)...

  10. Rise and Fall of a Coalition: The Supreme War Council and Marshal Foch, 1917-1919

    Science.gov (United States)

    2017-05-26

    Britain and France During the First World War ( Cambridge : Cambridge University Press, 2009), 169. 5 World Peace Foundation, “The Supreme War Council...Second World War conflict. It illustrated how unified policies as a coalition from the First World War served a reminder for strategists and operational...France During the First World War ( Cambridge : Cambridge University Press, 2009); Elizabeth Greenhalgh, Foch in Command: The Forging of a First World

  11. Book Review: Training the Party: Party Adaptation and Elite Training in Reform-era China

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    2016-01-01

    Review of: Training the Party: Party Adaptation and Elite Training in Reform-era China. Charlotte P. Lee . Cambridge: Cambridge University Press, 2015. xii + 251 pp. $99.99. ISBN 978-1-107-09063-7......Review of: Training the Party: Party Adaptation and Elite Training in Reform-era China. Charlotte P. Lee . Cambridge: Cambridge University Press, 2015. xii + 251 pp. $99.99. ISBN 978-1-107-09063-7...

  12. Complexity Theory and Network Centric Warfare

    Science.gov (United States)

    2003-09-01

    in Surface Growth. Cambridge University Press. Cambridge, UK. 10 MANDELBROT B (1997). Fractals and Scaling in Finance . Springer-Verlag. 11 TURNER A...to Econophysics; Correlations and Complexity in Finance . Cambridge University Press. Cambridge, UK. ADDITIONAL REFERENCE 14 PEITGEN H-O, JURGENS H...realms of the unknown. Defence thinkers everywhere are searching forward for the science and alchemy that will deliver operational success. CCRP

  13. Book Reviews

    OpenAIRE

    Redactie KITLV

    2003-01-01

    -Timothy Barnard, J.M. Gullick, A history of Selangor (1766-1939). Kuala Lumpur: Malaysian branch of the Royal Asiatic Society, 1989, vi + 220 pp. [MBRAS Monograph 28.] -Okke Braadbaart, Michael L. Ross, Timber booms and institutional breakdown in Southeast Asia. Cambridge: Cambridge University Press, 2001, xvi + 237 pp. -H.J.M. Claessen, Patrick Vinton Kirch ,Hawaiki, ancestral Polynesia; An essay in historical anthropology. Cambridge: Cambridge University Press, 2001, xvii + 375 pp., Roger ...

  14. Field Research in Political Science Practices and Principles

    DEFF Research Database (Denmark)

    Gravier, Magali

    2017-01-01

    Book review of: Kapiszewski (Diana), Maclean (Lauren M.), Read (Benjamin L.) ­ Field Research in Political Science. Practices and Principles. ­ Cambridge, Cambridge University Press, 2015 (Strategies for Social Inquiry). XIV + 456 p. Figures. Annexe. Bibliogr. Index.......Book review of: Kapiszewski (Diana), Maclean (Lauren M.), Read (Benjamin L.) ­ Field Research in Political Science. Practices and Principles. ­ Cambridge, Cambridge University Press, 2015 (Strategies for Social Inquiry). XIV + 456 p. Figures. Annexe. Bibliogr. Index....

  15. Elevated Ratio of Maternal Plasma ApoCIII to ApoCII in Preeclampsia

    Science.gov (United States)

    2011-05-01

    disease. Given the similarities in pathology, etiology , and clinical presentation between cardiovascular disease and preeclampsia , we hypothesized that...directed fetal/placental signals? In: Lyall F, Belfort M, eds. Preeclampsia : Etiology and Clinical Practice. Cambridge, UK: Cambridge University Press...2007:183-194. 3. Hubel C. Dyslipidemia and preeclampsia . In: Lyall F, Belfort M, eds. Preeclampsia : Etiology and Clinical Practice. Cambridge, UK

  16. 75 FR 15742 - NASA Advisory Council; Ad-Hoc Task Force on Planetary Defense; Meeting

    Science.gov (United States)

    2010-03-30

    ...: Notice of meeting. SUMMARY: In accordance with the Federal Advisory Committee Act, Public Law 92-463, as... Friday, April 16, 2010, 9 a.m.-1 p.m. (times are EDT). ADDRESSES: Boston Marriott Cambridge Hotel; Two Cambridge Center, 50 Broadway; Cambridge, Massachusetts 02142; (617) 494-6600. FOR FURTHER INFORMATION...

  17. Superior-subordinate relations as organizational processes

    DEFF Research Database (Denmark)

    Asmuss, Birte; Aggerholm, Helle Kryger; Oshima, Sae

    , E. (Eds) (2010): Cambridge Handbook of Strategy as Practice. Cambridge: Cambridge University Press. Maynard, D. (2003). Bad news, good news: Conversational order in everyday talk and clinical settings. Chicago: The University of Chicago Press. Mondada, L. (2009) ‘The embodied and negotiated...

  18. Last / Late Shakespeare? | Pearce | Shakespeare in Southern Africa

    African Journals Online (AJOL)

    Catherine M.S. Alexander (ed). The Cambridge Companion to Shakespeare's Last Plays. Cambridge: Cambridge University Press, 2009. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · http://dx.doi.org/10.4314/sisa.v24i1.11 · AJOL African Journals Online. HOW TO ...

  19. Patent holdings of US biotherapeutic companies in major markets.

    Science.gov (United States)

    Sebastian, Teena E; Yerram, Chandra Bindu; Saberwal, Gayatri

    2009-05-01

    In previous studies we examined the (United States, US) patent holdings of 109 largely North American biotech companies developing therapeutics that, in particular, have an interest in discovery stage science. There appears little correlation between the number of patents and the number of products of individual companies. Here we quantified and compared the 103 US-headquartered companies' patent holdings in Australia, Canada, Europe, Japan and the US. The companies demonstrate variable and surprising patterns of patent holdings across these countries or regions. For most companies, patent holdings are not in proportion to the importance of the country as a biotech or pharma market. These results have implications for the patenting strategies of small biotech companies involved in drug discovery.

  20. Nanobiotech in big pharma: a business perspective.

    Science.gov (United States)

    Würmseher, Martin; Firmin, Lea

    2017-03-01

    Since the early 2000s, numerous publications have presented major scientific opportunities that can be achieved through integrating insights from the area of nanotech into biotech (nanobiotech). This paper aims to explore the economic significance that nanobiotech has gained in the established pharmaceutical industry (big pharma). The empirical investigation draws on patent data as well as product revenue data; and to put the results into perspective, the amounts are compared with the established/traditional biotech sector. The results indicate that the new technology still plays only a minor role - at least from a commercial perspective.

  1. Biotecnologie in Europa. Rilevazione dei caratteri delle imprese in alcuni paesi

    OpenAIRE

    Frigero Piercarlo

    2003-01-01

    This is an attempt to survey the characteristics of firms in the European biotech industry. Databases of biotech firms on the web are reviewed to prepare a set of names useful for subsequent analysis. More than 650 firms are then chosen, through their patent applications to the European Patent Office and the US Patent and Trademark Office. Counting the number of patents is the first step in evaluating the role of national industry in 11 countries. To avoid unusable cases of patents not strict...

  2. Industry Responsibilities in Tackling Direct-to-Consumer Marketing of Unproven Stem Cell Treatments.

    Science.gov (United States)

    Master, Z; Fu, W; Paciulli, D; Sipp, D

    2017-08-01

    The direct-to-consumer marketing of unproven stem cell interventions (SCIs) is a serious public health concern. Regulations and education have had modest impact, indicating that different actors must play a role to stop this unfettered market. We consider the role of the biotech industry in tackling unproven SCIs. Grounded in the concept of corporate social responsibility, we argue that biotech companies should screen consumers to ensure that products and services are being used appropriately and educate employees about unproven SCIs. © 2017 ASCPT.

  3. New challenges and opportunities for industrial biotechnology.

    Science.gov (United States)

    Chen, Guo-Qiang

    2012-08-20

    Industrial biotechnology has not developed as fast as expected due to some challenges including the emergences of alternative energy sources, especially shale gas, natural gas hydrate (or gas hydrate) and sand oil et al. The weaknesses of microbial or enzymatic processes compared with the chemical processing also make industrial biotech products less competitive with the chemical ones. However, many opportunities are still there if industrial biotech processes can be as similar as the chemical ones. Taking advantages of the molecular biology and synthetic biology methods as well as changing process patterns, we can develop bioprocesses as competitive as chemical ones, these including the minimized cells, open and continuous fermentation processes et al.

  4. Financial Times Global Pharmaceutical & Biotechnology Conference 2009.

    Science.gov (United States)

    Scattereggia, Jennifer

    2010-01-01

    The Financial Times Global Pharmaceutical & Biotechnology conference, held in London, included topics covering the current and future challenges confronting the pharma and biotech industry, and presented possible solutions to those challenges. This conference report highlights selected presentations on the industry challenges for big pharma companies, diversification as a solution to industry problems, overcoming challenges with collaborations and M&As, and the role of emerging markets in the pharma industry. Other subjects discussed included the expected impact of personalized medicine on the industry, the entry of big pharma into the generics market and the problems that are confronting the small pharma and biotech industry.

  5. Research Strategies in Science-based Start-ups

    DEFF Research Database (Denmark)

    Valentin, Finn; Dahlgren, Johan Henrich; Lund Jensen, Rasmus

    develop a contingency view on complex problem solving which structures the argument into three steps:1) Characterising the problem architectures addressed by different types of DBFs;2) Testing and confirming that DBFs form requisite research strategies, by which we refer to problem solving approaches......Although biotech start-ups fail or succeed based on their research few attempts have been made to examine if and how they strategize in this core of their activity. Popular views on Dedicated Biotech Firms (DBFs) see the inherent uncertainty of research as defying notions of strategizing, directing...

  6. Offshoring of Innovation

    DEFF Research Database (Denmark)

    Haakonsson, Stine

    2013-01-01

    This chapter is an investigation into the internationalization of innovation in the Danish food-related biotech industry. The process of the internationalization of innovation in food and ingredients into new markets has followed a similar path: first, the companies enter new markets with their p......This chapter is an investigation into the internationalization of innovation in the Danish food-related biotech industry. The process of the internationalization of innovation in food and ingredients into new markets has followed a similar path: first, the companies enter new markets...

  7. Engineering insect-resistant crops: A review

    African Journals Online (AJOL)

    dgeorge

    African Journal of Biotechnology ... Transgenic crops engineered for enhanced levels of resistance to insect ... this background that research work targeting other candidate genes such as ... nisms, and potential deleterious environmental effects. ... The global market value of biotech crops was esti- .... located in repeat 11.

  8. Ethical perception of modern biotechnology

    African Journals Online (AJOL)

    Jane

    2011-09-30

    Sep 30, 2011 ... 1Social Impact of Biotechnology Development in Malaysia Research ... purpose of this paper is to examine the ethical perception of modern ... and social benefits of modern biotechnology, consumer .... Company or organisation directly involved in the production of ...... Food safety battle: organic vs. biotech.

  9. Kernel compositions of glyphosate-tolerant and corn rootworm-protected MON 88017 sweet corn and insect-protected MON 89034 sweet corn are equivalent to that of conventional sweet corn (Zea mays).

    Science.gov (United States)

    Curran, Kassie L; Festa, Adam R; Goddard, Scott D; Harrigan, George G; Taylor, Mary L

    2015-03-25

    Monsanto Co. has developed two sweet corn hybrids, MON 88017 and MON 89034, that contain biotechnology-derived (biotech) traits designed to enhance sustainability and improve agronomic practices. MON 88017 confers benefits of glyphosate tolerance and protection against corn rootworm. MON 89034 provides protection against European corn borer and other lepidopteran insect pests. The purpose of this assessment was to compare the kernel compositions of MON 88017 and MON 89034 sweet corn with that of a conventional control that has a genetic background similar to the biotech sweet corn but does not express the biotechnology-derived traits. The sweet corn samples were grown at five replicated sites in the United States during the 2010 growing season and the conventional hybrid and 17 reference hybrids were grown concurrently to provide an estimate of natural variability for all assessed components. The compositional analysis included proximates, fibers, amino acids, sugars, vitamins, minerals, and selected metabolites. Results highlighted that MON 88017 and MON 89034 sweet corns were compositionally equivalent to the conventional control and that levels of the components essential to the desired properties of sweet corn, such as sugars and vitamins, were more affected by growing environment than the biotech traits. In summary, the benefits of biotech traits can be incorporated into sweet corn with no adverse effects on nutritional quality.

  10. Taming Living Logic using Formal Methods

    DEFF Research Database (Denmark)

    Baig, Hasan; Madsen, Jan

    2017-01-01

    One of the goals of synthetic biology is to build genetic circuits to control the behavior of a cell for different application domains, such as medical, environmental, and biotech. During the design process of genetic circuits, biologists are often interested in the probability of a system to work...

  11. CYTOKINE - The Official Journal of the International Cytokine Society. Volume 11, Number 11

    Science.gov (United States)

    1999-12-09

    using the contour-clamped homogeneous electric field ( CHEF ) system (Pulsaphor Plus; Pharmacia LKB Biotech- nology, Uppsala, Sweden). The conditions...reactive oxygen intermediates (ROI) are frequent companions at sites of acute inflammation. We have previously shown that in human monocytes LPS, IL-1 and

  12. Advances in Protein Precipitation

    NARCIS (Netherlands)

    Golubovic, M.

    2009-01-01

    Proteins are biological macromolecules, which are among the key components of all living organisms. Proteins are nowadays present in all fields of biotech industry, such as food and feed, synthetic and pharmaceutical industry. They are isolated from their natural sources or produced in different

  13. Networked Success and Failure at Hybritech

    Science.gov (United States)

    Jones, Mark Peter

    2011-01-01

    The author presents an historical account of scientific work conducted at a commercial biotech firm in San Diego called Hybritech. It tells of disruptions in research programs following the acquisition of the company by the pharmaceutical giant Eli Lilly in 1986. The story centers on responses to an organizational challenge that research managers…

  14. Akadeemikust ettevõtja võitleb viirustega / Kaire Talviste

    Index Scriptorium Estoniae

    Talviste, Kaire, 1979-

    2012-01-01

    Molekulaarbioloog Mart Ustavi tööst bioloogiliste ravimite väljatöötamisel. HIV1/AIDS vaktsiini väljatöötamisest FIT Biotech Oy Eesti filiaalis a-tel 2000-2011. M. Ustavi biotehnoloogia firma Icosagen Grupp tehnoloogilistest arendustest

  15. Reduction of Exudates (Browning) in Sugarcane Micro Propagation ...

    African Journals Online (AJOL)

    ... of this variety, ascorbic acid and citric acid was added as constituent of the media using MS and stock at different concentrations. The browning was reduced drastically at the addition of 0.1g/litre ascorbic acid and 0.15g/litre citric acid. Keywords: reduction, exudates browning, micro propagation, sugarcane. Nig J. Biotech.

  16. Eesti HIVi alatüüp jõuab registrisse / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2005-01-01

    Ülemaailmses HIV- andmebaasis on registreerimisel HI-viiruse alatüüp, mida on seni avastatud ainult Eestis. Mosaiik-HIV on segu peamiselt Aafrikas esinevast viiruse vormist ning Ukrainas levinud tüübist, selgub biotehnoloogiafirma FIT Biotech uuringust. Kommenteerib Tartu Ülikooli tehnoloogiainstituudi direktor Mart Ustav

  17. American Farm Bureau Foundation for Agriculture - Homepage

    Science.gov (United States)

    Literacy? What We Do Resources Sustainable Agriculture Food and Farm Facts Free Resources & Lesson Agriculture Food and Farm Facts Free Resources & Lesson Plans Bringing Biotech to Life Learn About Beef and their families about agriculture at the USA Science & Engineering Festival in April. Read More

  18. Eesti firma hakkab koostöös soomlastega välja töötama Ebola viiruse ravimit / Joosep Värk

    Index Scriptorium Estoniae

    Värk, Joosep

    2014-01-01

    Eesti biotehnoloogiafirma Icosagen hakkab koos Soome ettevõtte FIT Biotech Oy'ga välja töötama Ebola viiruse vastast vaktsiini, arendustöös osaleb professor Andres Meritsa juhtimisel ka Tartu Ülikooli Tehnoloogiainstituudi rakendusviroloogia labor. Vestlusest Tartu Ülikooli biomeditsiinitehnoloogia professori Mart Ustaviga

  19. Tartu teadlased aitavad välja mõelda Ebola-vastast vaktsiini / Aime Jõgi

    Index Scriptorium Estoniae

    Jõgi, Aime, 1958-

    2014-01-01

    Eesti biotehnoloogiafirma Icosagen hakkab koos Soome ettevõtte FIT Biotech Oy'ga välja töötama Ebola viiruse vastast vaktsiini, arendustöös osaleb ka Tartu Ülikooli Tehnoloogiainstituudi rakendusviroloogia labor

  20. Yathindra, Prof. Narayanarao

    Indian Academy of Sciences (India)

    Narayanarao Ph.D. (Madras). Date of birth: 12 March 1944. Specialization: Computational Structural Biology Address: Director, Institute of Bioinformatics and Applied Biotechnology, Biotech Park (Next to Arvind Mills), Electronic City, Phase 1 (Behind 3M), Bengaluru 560 100, Karnataka Contact: Office: (080) 2852 8900-03

  1. INNOVATIVE AND INDUSTRIAL-PERFORMANCE IN PHARMACEUTICAL RESEARCH-AND-DEVELOPMENT, A MANAGEMENT CONTROL PERSPECTIVE

    NARCIS (Netherlands)

    OMTA, SWF; BOUTER, LM; VANENGELEN, JML

    In this paper management control is related to innovative and industrial performance in 14 non-biotech pharmaceutical companies. The study consisted of questionnaires, sent to the heads of the different research departments of European research laboratories of leading pharmaceutical companies,

  2. Academic Centers and/as Industrial Consortia: US Microelectronics Research 1976-2016

    NARCIS (Netherlands)

    Mody, Cyrus C.M.

    2017-01-01

    In the U.S., in the late 1970s and early 1980s, academic research centers that were tightly linked to the semiconductor industry began to proliferate – at exactly the same time as the first academic start-up companies in biotech, and slightly before the first U.S. industrial semiconductor research

  3. Development of somaclones in sugarcane genotype BF-162 and ...

    African Journals Online (AJOL)

    pris

    2012-02-21

    Feb 21, 2012 ... Baksha R, Alam R, Karim MZ, Paul SK, Hossain MA, Miah MAS,. Rahman ABMM (2002). In vitro Shoot Tip Culture of Sugarcane. (Saccharum officinarum) Variety Isd 28. Int. Quarterly J. Biotech. 1: 67-72. Brisibe E, Miyake AH, Taniguchi T, Maeda E (1994). Regulation of somatic embryogenesis in long-term ...

  4. Technology and international strategies in born global firms: evidence from The Netherlands

    NARCIS (Netherlands)

    Anne van Delft; Sumit Kundu; Hein Roelfsema

    2010-01-01

    This paper analyzes the internationalization strategies of biotech firms in the Netherlands. We find that many of these firms are born internationals in the sense that from their inception they are actively engaged in international cooperation. However, we find that the nature of potential

  5. Pages 522 - 529.pmd

    African Journals Online (AJOL)

    Administrator

    Objective: To compare the ANGPTL3 mRNA and protein expression, exon mutation and promoter district CpG island methylation state ... tissue samples (the liver, muscle (lean meat, lean) and ... ice-cold Trizol reagent (Changsha Axybio bio-tech ... To synthesize single- .... normalized, temperature-shifted, difference curves.

  6. Hepatitis B virus surface antigen and anti-hepatitis C virus rapid tests underestimate hepatitis prevalence among HIV-infected patients

    DEFF Research Database (Denmark)

    Hønge, Bo Langhoff; Jespersen, S; Medina, C

    2014-01-01

    . RESULTS: Two rapid tests were used in Guinea-Bissau: HBsAg Strip Ref 2034 (VEDA.LAB, Alençon, France; sensitivity 62.3%; specificity 99.2%) and HEPA-SCAN (Bhat Bio-Tech, Bangalore, India; sensitivity 57.1%; specificity 99.7%). In the two tests the ability to obtain the correct outcome depended...

  7. Biotechnology Education in India: An Overview

    Science.gov (United States)

    Joshi, Kirti; Mehra, Kavita; Govil, Suman; Singh, Nitu

    2013-01-01

    Among the developing countries, India is one of those that recognises the importance of biotechnology. The trajectory of different policies being formulated over time is proof that the government is progressing towards achieving self-sufficiency. However, to cater to the ever-growing biotech industry, skilled manpower is required. This article…

  8. Recent advances in smart biotechnology

    DEFF Research Database (Denmark)

    Milcovich, Gesmi; Lettieri, Stefania; Antunes, Filipe E.

    2017-01-01

    Over the past ten years, the global biopharmaceutical market has remarkably grown, with ten over the top twenty worldwide high performance medical treatment sales being biologics. Thus, biotech R&D (research and development) sector is becoming a key leading branch, with expanding revenues. Biotec...

  9. Experiment list: SRX262791 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available IH3T3_MRTFB_LAT || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-B || chip antibody vendor=Santa Cruz Biotech...nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea

  10. Experiment list: SRX262787 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available IH3T3_MRTFA_LAT || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-A || chip antibody vendor=Santa Cruz Biotech...nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea

  11. Preliminary format design guidelines

    DEFF Research Database (Denmark)

    Tosello, Guido; Calaon, Matteo; Nørregaard, J.

    2013-01-01

    The strategic research centre PolyNano aims at becoming the Danish competence centre for production-ready fabrication of polymer, nano-scale lab-on-a-chip (LoC) devices. In order to provide a competitive edge for Danish biotech companies launching LoC products by removal of the technology barrier...

  12. Smallholder adoption and economic impacts of tissue culture ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-01

    Dec 1, 2009 ... ISSN 1684–5315 © 2009 Academic Journals. Full Length ... Key words: Biotechnology, adoption, tissue culture bananas, Kenya. INTRODUCTION ... Recent studies about the agronomic and economic impacts of biotech- ..... accused scientist for 'playing God', others have supported biotechnologies.

  13. 76 FR 44924 - Cardinal Health, Inc.; Analysis of Agreement Containing Consent Order to Aid Public Comment

    Science.gov (United States)

    2011-07-27

    ... Nuclear pharmacies provide radiopharmaceuticals to local hospitals and cardiology clinics, which use the... prohibiting unfair or deceptive acts or practices or unfair methods of competition. The attached Analysis to... Cardinal's acquisition of Biotech's nuclear pharmacies in the Southwestern United States. Under the terms...

  14. Ryntäys Viroon jatkuu / Eeva-Riitta Seies

    Index Scriptorium Estoniae

    Seies, Eeva-Riitta

    2002-01-01

    Soome kontsern Vapo ostis ASi Tootsi Turvas enamusaktsiad. Soome ettevõte Fit Biotech ostis Tartu biotehnoloogiaettevõtte Quattromed ja Soome toiduainetetööstuse ettevõte Saarioinen Oy Eesti tütarfirma omandas üle 66-protsendilise osaluse valmistoidufirmas Meleco AS

  15. Pikkani osalusega ettevõte jahib rahamahukat geenianalüüsi / Väinu Rozental

    Index Scriptorium Estoniae

    Rozental, Väinu, 1957-

    2002-01-01

    Geenivaramu lepingusüsteem mängib geenianalüüsi tegemisel suured trumbid kätte geenivaramu eestvedajate Jaanus Pikani ja Andres Metspalu osalusega Tartus geenianalüüsiga tegelevale AS-ile Asper Biotech

  16. Xiao et al., Afr J Tradit Complement Altern Med. (2013) 10(6):444 ...

    African Journals Online (AJOL)

    cadewumi

    in Lewis lung carcinoma-bearing mice and determination of the number of NK cells ... included Mouse CD4+, CD8+, antibody, Lianke Biotech Co., Ltd., Shanghai; .... The growth of transplanted lung tumours in mice of Solanum lyratum Thunb ...

  17. Production of Microbial Protease from Selected Soil Fungal Isolates ...

    African Journals Online (AJOL)

    Production of Microbial Protease from Selected Soil Fungal Isolates. ... Nigerian Journal of Biotechnology ... and 500C. The optimal pH on the enzyme production was observed to be between pH 3.5 and 5.5 for the organisms. Keywords: Soil microorganism, fungal isolate, incubation period, microbial enzyme. Nig J. Biotech.

  18. Unlocking the full potential of Open Innovation in the Life Sciences through a classification system

    DEFF Research Database (Denmark)

    Nilsson, Niclas; Minssen, Timo

    2018-01-01

    Open Innovation (OI) holds much promise as a new business model for collaborative value creation in life science. From a corporate perspective, benefits include faster access to new relevant technology; the opportunity for Biotechs and Small to Medium-sized Enterprises (SMEs) to explore new marke...

  19. A universal, rapid, and inexpensive method for genomic DNA ...

    Indian Academy of Sciences (India)

    MOHAMMED BAQUR SAHIB A. AL-SHUHAIB

    gels, containing 7% glycerol, and 1×TBE buffer. The gels were run under 200 .... Inc. Germany, GeneaidTM DNA Isolation Kit, Geneaid. Biotech., New Taipei City, .... C. L. and Arsenos G. 2015 Comparison of eleven methods for genomic DNA ...

  20. Soybean Peptide as Additive on Yellow Feather Broiler Chicks ...

    African Journals Online (AJOL)

    GM soybean and sold on the Chinese market by China CF Duqing (Heze) Biotech Co. Ltd, Shandong Prov-ince, China. For the purpose of this study, the peptide was designated marketed soybean peptide (MSBP). In order to show its efficacy ...