WorldWideScience

Sample records for box planting

  1. Regulating the ethylene response of a plant by modulation of F-box proteins

    Science.gov (United States)

    Guo, Hongwei [Beijing, CN; Ecker, Joseph R [Carlsbad, CA

    2014-01-07

    The relationship between F-box proteins and proteins invovled in the ethylene response in plants is described. In particular, F-box proteins may bind to proteins involved in the ethylene response and target them for degradation by the ubiquitin/proteasome pathway. The transcription factor EIN3 is a key transcription factor mediating ethylne-regulated gene expression and morphological responses. EIN3 is degraded through a ubiquitin/proteasome pathway mediated by F-box proteins EBF1 and EBF2. The link between F-box proteins and the ethylene response is a key step in modulating or regulating the response of a plant to ethylene. Described herein are transgenic plants having an altered sensitivity to ethylene, and methods for making transgenic plant haing an althered sensitivity to ethylene by modulating the level of activity of F-box proteins. Methods of altering the ethylene response in a plant by modulating the activity or expression of an F-box protein are described. Also described are methods of identifying compounds that modulate the ethylene response in plants by modulating the level of F-box protein expression or activity.

  2. MADS-box genes in plant ontogeny and phylogeny: Haeckel's 'biogenetic law' revisited.

    Science.gov (United States)

    Theissen, G; Saedler, H

    1995-10-01

    Data currently accumulating with impressive speed indicate that the molecular evolution of MADS-box genes was a decisive aspect of the morphological evolution of plants. Studies on MADS-box genes in diverse plant species thus help us to understand the emergence of morphological novelties, such as the flower, in evolution. This furthers our understanding of the relationship between ontogeny and phylogeny, which has been a controversial issue since Ernst Haeckel published his 'biogenetic law' more than a century ago.

  3. The F-box gene family is expanded in herbaceous annual plants relative to woody perennial plants.

    Science.gov (United States)

    Yang, Xiaohan; Kalluri, Udaya C; Jawdy, Sara; Gunter, Lee E; Yin, Tongming; Tschaplinski, Timothy J; Weston, David J; Ranjan, Priya; Tuskan, Gerald A

    2008-11-01

    F-box proteins are generally responsible for substrate recognition in the Skp1-Cullin-F-box complexes that are involved in protein degradation via the ubiquitin-26S proteasome pathway. In plants, F-box genes influence a variety of biological processes, such as leaf senescence, branching, self-incompatibility, and responses to biotic and abiotic stresses. The number of F-box genes in Populus (Populus trichocarpa; approximately 320) is less than half that found in Arabidopsis (Arabidopsis thaliana; approximately 660) or Oryza (Oryza sativa; approximately 680), even though the total number of genes in Populus is equivalent to that in Oryza and 1.5 times that in Arabidopsis. We performed comparative genomics analysis between the woody perennial plant Populus and the herbaceous annual plants Arabidopsis and Oryza in order to explicate the functional implications of this large gene family. Our analyses reveal interspecific differences in genomic distribution, orthologous relationship, intron evolution, protein domain structure, and gene expression. The set of F-box genes shared by these species appear to be involved in core biological processes essential for plant growth and development; lineage-specific differences primarily occurred because of an expansion of the F-box genes via tandem duplications in Arabidopsis and Oryza. The number of F-box genes in the newly sequenced woody species Vitis (Vitis vinifera; 156) and Carica (Carica papaya; 139) is similar to that in Populus, supporting the hypothesis that the F-box gene family is expanded in herbaceous annual plants relative to woody perennial plants. This study provides insights into the relationship between the structure and composition of the F-box gene family in herbaceous and woody species and their associated developmental and physiological features.

  4. Efficient ASK-assisted system for expression and purification of plant F-box proteins.

    Science.gov (United States)

    Li, Haiou; Yao, Ruifeng; Ma, Sui; Hu, Shuai; Li, Suhua; Wang, Yupei; Yan, Chun; Xie, Daoxin; Yan, Jianbin

    2017-09-05

    Ubiquitin-mediated protein degradation plays an essential role in plant growth and development as well as responses to environmental and endogenous signals. F-box protein is one of the key components of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which recruit specific substrate proteins for subsequent ubiquitination and 26S proteasome-mediated degradation to regulate developmental processes and signaling networks. However, it is not easy to obtain purified F-box proteins with high activity due to their unstable protein structures. Here, we found that Arabidopsis SKP-like proteins (ASKs) can significantly improve soluble expression of F-box proteins and maintain their bioactivity. We established an efficient ASK-assisted method to express and purify plant F-box proteins. The method meets a broad range of criteria required for the biochemical analysis or protein crystallization of plant F-box proteins. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

  5. The use of light-proof boxes for the measurements of plant vigour in ...

    African Journals Online (AJOL)

    The light-proof box method was used to measure the potential vigour of cocksfoot and lucerne plants which had previously been subjected to different cutting frequencies. The yields of etiolated regrowth in cocksfoot plants that were well supplied with soil moisture declined with each successive harvest. In the lucerne trial ...

  6. MADS goes genomic in conifers: towards determining the ancestral set of MADS-box genes in seed plants.

    Science.gov (United States)

    Gramzow, Lydia; Weilandt, Lisa; Theißen, Günter

    2014-11-01

    MADS-box genes comprise a gene family coding for transcription factors. This gene family expanded greatly during land plant evolution such that the number of MADS-box genes ranges from one or two in green algae to around 100 in angiosperms. Given the crucial functions of MADS-box genes for nearly all aspects of plant development, the expansion of this gene family probably contributed to the increasing complexity of plants. However, the expansion of MADS-box genes during one important step of land plant evolution, namely the origin of seed plants, remains poorly understood due to the previous lack of whole-genome data for gymnosperms. The newly available genome sequences of Picea abies, Picea glauca and Pinus taeda were used to identify the complete set of MADS-box genes in these conifers. In addition, MADS-box genes were identified in the growing number of transcriptomes available for gymnosperms. With these datasets, phylogenies were constructed to determine the ancestral set of MADS-box genes of seed plants and to infer the ancestral functions of these genes. Type I MADS-box genes are under-represented in gymnosperms and only a minimum of two Type I MADS-box genes have been present in the most recent common ancestor (MRCA) of seed plants. In contrast, a large number of Type II MADS-box genes were found in gymnosperms. The MRCA of extant seed plants probably possessed at least 11-14 Type II MADS-box genes. In gymnosperms two duplications of Type II MADS-box genes were found, such that the MRCA of extant gymnosperms had at least 14-16 Type II MADS-box genes. The implied ancestral set of MADS-box genes for seed plants shows simplicity for Type I MADS-box genes and remarkable complexity for Type II MADS-box genes in terms of phylogeny and putative functions. The analysis of transcriptome data reveals that gymnosperm MADS-box genes are expressed in a great variety of tissues, indicating diverse roles of MADS-box genes for the development of gymnosperms. This study is

  7. A Role for the F-Box Protein HAWAIIAN SKIRT in Plant microRNA Function.

    Science.gov (United States)

    Lang, Patricia L M; Christie, Michael D; Dogan, Ezgi S; Schwab, Rebecca; Hagmann, Jörg; van de Weyer, Anna-Lena; Scacchi, Emanuele; Weigel, Detlef

    2018-01-01

    As regulators of gene expression in multicellular organisms, microRNAs (miRNAs) are crucial for growth and development. Although a plethora of factors involved in their biogenesis and action in Arabidopsis (Arabidopsis thaliana) has been described, these processes and their fine-tuning are not fully understood. Here, we used plants expressing an artificial miRNA target mimic (MIM) to screen for negative regulators of miR156. We identified a new mutant allele of the F-box gene HAWAIIAN SKIRT (HWS; At3G61590), hws-5, as a suppressor of the MIM156-induced developmental and molecular phenotypes. In hws plants, levels of some endogenous miRNAs are increased and their mRNA targets decreased. Plants constitutively expressing full-length HWS-but not a truncated version lacking the F-box domain-display morphological and molecular phenotypes resembling those of mutants defective in miRNA biogenesis and activity. In combination with such mutants, hws loses its delayed floral organ abscission ("skirt") phenotype, suggesting epistasis. Also, the hws transcriptome profile partially resembles those of well-known miRNA mutants hyl1-2, se-3, and ago1-27, pointing to a role in a common pathway. We thus propose HWS as a novel, F-box dependent factor involved in miRNA function. © 2018 American Society of Plant Biologists. All Rights Reserved.

  8. The MADS-box gene SlMBP11 regulates plant architecture and affects reproductive development in tomato plants.

    Science.gov (United States)

    Guo, Xuhu; Chen, Guoping; Naeem, Muhammad; Yu, Xiaohu; Tang, Boyan; Li, Anzhou; Hu, Zongli

    2017-05-01

    MADS-domain proteins are important transcription factors that are involved in many biological processes of plants. In the present study, SlMBP11, a member of the AGL15 subfamily, was cloned in tomato plants (Solanum lycopersicon M.). SlMBP11 is ubiquitously expressed in all of the tissues we examined, whereas the SlMBP11 transcription levels were significantly higher in reproductive tissues than in vegetative tissues. Plants exhibiting increased SlMBP11 levels displayed reduced plant height, leaf size, and internode length as well as a loss of dominance in young seedlings, highly branched growth from each leaf axil, and increased number of nodes and leaves. Moreover, overexpression lines also exhibited reproductive phenotypes, such as those having a shorter style and split ovary, leading to polycarpous fruits, while the wild type showed normal floral organization. In addition, delayed perianth senescence was observed in transgenic tomatoes. These phenotypes were further confirmed by analyzing the morphological, anatomical and molecular features of lines exhibiting overexpression. These results suggest that SlMBP11 plays an important role in regulating plant architecture and reproductive development in tomato plants. These findings add a new class of transcription factors to the group of genes controlling axillary bud growth and illuminate a previously uncharacterized function of MADS-box genes in tomato plants. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Gene expression profiling--Opening the black box of plant ecosystem responses to global change

    Energy Technology Data Exchange (ETDEWEB)

    Leakey, A.D.B.; Ainsworth, E.A.; Bernard, S.M.; Markelz, R.J.C.; Ort, D.R.; Placella, S.A.P.; Rogers, A.; Smith, M.D.; Sudderth, E.A.; Weston, D.J.; Wullschleger, S.D.; Yuan, S.

    2009-11-01

    The use of genomic techniques to address ecological questions is emerging as the field of genomic ecology. Experimentation under environmentally realistic conditions to investigate the molecular response of plants to meaningful changes in growth conditions and ecological interactions is the defining feature of genomic ecology. Since the impact of global change factors on plant performance are mediated by direct effects at the molecular, biochemical and physiological scales, gene expression analysis promises important advances in understanding factors that have previously been consigned to the 'black box' of unknown mechanism. Various tools and approaches are available for assessing gene expression in model and non-model species as part of global change biology studies. Each approach has its own unique advantages and constraints. A first generation of genomic ecology studies in managed ecosystems and mesocosms have provided a testbed for the approach and have begun to reveal how the experimental design and data analysis of gene expression studies can be tailored for use in an ecological context.

  10. Gene Expression Profiling - Opening the Black Box of Plant Ecosystem Responses to Global Change

    Energy Technology Data Exchange (ETDEWEB)

    Ainsworth, Elizabeth A. [USDA-ARS, Urbana, IL; Bernard, Stephanie M. [University of California, Berkeley; Markelz, R.J. Cody [University of Illinois; Ort, Donald R. [USDA-ARS, Urbana, IL; Placella, Sarah A. [University of California, Berkeley; Rogers, Alistair [ORNL; Smith, Melinda D [Yale University; Sudderth, Erika A. [University of California, Berkeley; Weston, David [ORNL; Wullschleger, Stan D [ORNL; Yuan, Shenghua [Yale University

    2009-01-01

    The use of genomic techniques to address ecological questions is emerging as the field of genomic ecology. Experimentation under environmentally realistic conditions to investigate the molecular response of plants to meaningful changes in growth conditions and ecological interactions is the defining feature of genomic ecology. Since the impact of global change factors on plant performance are mediated by direct effects at the molecular, biochemical and physiological scales, gene expression analysis promises important advances in understanding factors that have previously been consigned to the black box of unknown mechanism. Various tools and approaches are available for assessing gene expression in model and non-model species as part of global change biology studies. Each approach has its own unique advantages and constraints. A first generation of genomic ecology studies in managed ecosystems and mesocosms have provided a testbed for the approach and have begun to reveal how the experimental design and data analysis of gene expression studies can be tailored for use in an ecological context.

  11. News from the PUB: plant U-box type E3 ubiquitin ligases.

    Science.gov (United States)

    Trujillo, Marco

    2018-01-23

    Plant U-box type E3 ubiquitin ligases (PUBs) are well known for their functions in a variety of stress responses, including immune responses and the adaptation to abiotic stresses. First linked to pollen self-incompatibility, their repertoire of roles has grown to encompass also the regulation of developmental processes. Notably, new studies provide clues to their mode of action, underline the existence of conserved PUB-kinase modules, and suggest new links to G-protein signalling, placing PUBs at the crossroads of major signalling hubs. The frequent association with membranes, by interacting and/or targeting membrane proteins, as well as through a recently reported direct interaction with phospholipids, indicates a general function in the control of vesicle transport and their cargoes. This review aims to give an overview of the most significant advances in the field, while also trying to identify common themes of PUB function. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  12. Arrival of the cold box for the cryogenic refrigeration plant and installation in building SHL5.

    CERN Multimedia

    Goran Perinic

    2002-01-01

    The pictures show the arrival of the cold box and the installation of both the cold box and the valve panel in building SHL5. The installation was achieved by lowering the components through an opening in the roof which had been specially forseen for this operation.

  13. A Role for the F-Box Protein HAWAIIAN SKIRT in Plant microRNA Function1[OPEN

    Science.gov (United States)

    Christie, Michael D.; Dogan, Ezgi S.; Schwab, Rebecca; Hagmann, Jörg; van de Weyer, Anna-Lena; Scacchi, Emanuele

    2018-01-01

    As regulators of gene expression in multicellular organisms, microRNAs (miRNAs) are crucial for growth and development. Although a plethora of factors involved in their biogenesis and action in Arabidopsis (Arabidopsis thaliana) has been described, these processes and their fine-tuning are not fully understood. Here, we used plants expressing an artificial miRNA target mimic (MIM) to screen for negative regulators of miR156. We identified a new mutant allele of the F-box gene HAWAIIAN SKIRT (HWS; At3G61590), hws-5, as a suppressor of the MIM156-induced developmental and molecular phenotypes. In hws plants, levels of some endogenous miRNAs are increased and their mRNA targets decreased. Plants constitutively expressing full-length HWS—but not a truncated version lacking the F-box domain—display morphological and molecular phenotypes resembling those of mutants defective in miRNA biogenesis and activity. In combination with such mutants, hws loses its delayed floral organ abscission (“skirt”) phenotype, suggesting epistasis. Also, the hws transcriptome profile partially resembles those of well-known miRNA mutants hyl1-2, se-3, and ago1-27, pointing to a role in a common pathway. We thus propose HWS as a novel, F-box dependent factor involved in miRNA function. PMID:29114080

  14. A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature.

    Science.gov (United States)

    Liu, Yuelin; Tabata, Daisuke; Imai, Ryozo

    2016-01-01

    DEAD-box RNA helicases comprise a large family and are involved in a range of RNA processing events. Here, we identified one of the Arabidopsis thaliana DEAD-box RNA helicases, AtRH7, as an interactor of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 (AtCSP3), which is an RNA chaperone involved in cold adaptation. Promoter:GUS transgenic plants revealed that AtRH7 is expressed ubiquitously and that its levels of the expression are higher in rapidly growing tissues. Knockout mutant lines displayed several morphological alterations such as disturbed vein pattern, pointed first true leaves, and short roots, which resemble ribosome-related mutants of Arabidopsis. In addition, aberrant floral development was also observed in rh7 mutants. When the mutants were germinated at low temperature (12°C), both radicle and first leaf emergence were severely delayed; after exposure of seedlings to a long period of cold, the mutants developed aberrant, fewer, and smaller leaves. RNA blots and circular RT-PCR revealed that 35S and 18S rRNA precursors accumulated to higher levels in the mutants than in WT under both normal and cold conditions, suggesting the mutants are partially impaired in pre-rRNA processing. Taken together, the results suggest that AtRH7 affects rRNA biogenesis and plays an important role in plant growth under cold.

  15. A Cold-Inducible DEAD-Box RNA Helicase from Arabidopsis thaliana Regulates Plant Growth and Development under Low Temperature.

    Directory of Open Access Journals (Sweden)

    Yuelin Liu

    Full Text Available DEAD-box RNA helicases comprise a large family and are involved in a range of RNA processing events. Here, we identified one of the Arabidopsis thaliana DEAD-box RNA helicases, AtRH7, as an interactor of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 (AtCSP3, which is an RNA chaperone involved in cold adaptation. Promoter:GUS transgenic plants revealed that AtRH7 is expressed ubiquitously and that its levels of the expression are higher in rapidly growing tissues. Knockout mutant lines displayed several morphological alterations such as disturbed vein pattern, pointed first true leaves, and short roots, which resemble ribosome-related mutants of Arabidopsis. In addition, aberrant floral development was also observed in rh7 mutants. When the mutants were germinated at low temperature (12°C, both radicle and first leaf emergence were severely delayed; after exposure of seedlings to a long period of cold, the mutants developed aberrant, fewer, and smaller leaves. RNA blots and circular RT-PCR revealed that 35S and 18S rRNA precursors accumulated to higher levels in the mutants than in WT under both normal and cold conditions, suggesting the mutants are partially impaired in pre-rRNA processing. Taken together, the results suggest that AtRH7 affects rRNA biogenesis and plays an important role in plant growth under cold.

  16. Peeking into the black box: A trait-based approach to predicting plant-soil feedback

    NARCIS (Netherlands)

    Kardol, P.; Veen, G.F.; Teste, F.P.; Perring, M.P.

    2015-01-01

    Feedbacks between plants and soil communities may be elusive, yet they have far-reaching consequences for plant physiology, competition and community structure. Plant–soil feedbacks (PSFs) are plant-mediated changes to soil properties that ultimately influence the performance of the same or other

  17. EG & G Mount Plant, December 1990 and January 1991, D & D soil box sampling

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-04-01

    Six hundred eighty-two (682) containers of soil were generated at Mound Plant between April 1 and October 31, 1990 as a result of the excavation of soils containing plutonium-238 at two ongoing Decontamination and Decommissioning (D&D) Program sites; these areas are known as Area 14, the waste transfer system (WTS) hillside, and Area 17, the Special Metallurgical (SM) Building Area. The soils from these areas are part of the Mound Plant waste stream number AMDM-000000010, Contaminated Soil, and are proposed for shipment to the Nevada Test Site (NTS) for disposal as low-level radioactive waste. These containers of soil are currently in storage at Mound Plant. The purpose of this sampling and analysis was to demonstrate that the D&D soils comply with the waste acceptance requirements of the NTS, as presented In Nevada Test Site Defense Waste Acceptance Criteria, Certification, and Transfer Requirements (DOE 1988). The sealed waste packages, constructed of wood or metal, are currently being stored In Building 31 and at other locations throughout the Mound Plant. For additional historical information concerning the D&D soils, Including waste stream evaluations and past sampling data see the Sampling and Analysis Plan for Mound Plant D&D Soils Packages (EG&G 1991).

  18. Monte Carlo simulation of a clearance box monitor used for nuclear power plant decommissioning.

    Science.gov (United States)

    Bochud, François O; Laedermann, Jean-Pascal; Bailat, Claude J; Schuler, Christoph

    2009-05-01

    When decommissioning a nuclear facility it is important to be able to estimate activity levels of potentially radioactive samples and compare with clearance values defined by regulatory authorities. This paper presents a method of calibrating a clearance box monitor based on practical experimental measurements and Monte Carlo simulations. Adjusting the simulation for experimental data obtained using a simple point source permits the computation of absolute calibration factors for more complex geometries with an accuracy of a bit more than 20%. The uncertainty of the calibration factor can be improved to about 10% when the simulation is used relatively, in direct comparison with a measurement performed in the same geometry but with another nuclide. The simulation can also be used to validate the experimental calibration procedure when the sample is supposed to be homogeneous but the calibration factor is derived from a plate phantom. For more realistic geometries, like a small gravel dumpster, Monte Carlo simulation shows that the calibration factor obtained with a larger homogeneous phantom is correct within about 20%, if sample density is taken as the influencing parameter. Finally, simulation can be used to estimate the effect of a contamination hotspot. The research supporting this paper shows that activity could be largely underestimated in the event of a centrally-located hotspot and overestimated for a peripherally-located hotspot if the sample is assumed to be homogeneously contaminated. This demonstrates the usefulness of being able to complement experimental methods with Monte Carlo simulations in order to estimate calibration factors that cannot be directly measured because of a lack of available material or specific geometries.

  19. TC-motifs at the TATA-box expected position in plant genes: a novel class of motifs involved in the transcription regulation

    Directory of Open Access Journals (Sweden)

    Lecharny Alain

    2010-03-01

    Full Text Available Abstract Background The TATA-box and TATA-variants are regulatory elements involved in the formation of a transcription initiation complex. Both have been conserved throughout evolution in a restricted region close to the Transcription Start Site (TSS. However, less than half of the genes in model organisms studied so far have been found to contain either one of these elements. Indeed different core-promoter elements are involved in the recruitment of the TATA-box-binding protein. Here we assessed the possibility of identifying novel functional motifs in plant genes, sharing the TATA-box topological constraints. Results We developed an ab-initio approach considering the preferential location of motifs relative to the TSS. We identified motifs observed at the TATA-box expected location and conserved in both Arabidopsis thaliana and Oryza sativa promoters. We identified TC-elements within non-TA-rich promoters 30 bases upstream of the TSS. As with the TATA-box and TATA-variant sequences, it was possible to construct a unique distance graph with the TC-element sequences. The structural and functional features of TC-element-containing genes were distinct from those of TATA-box- or TATA-variant-containing genes. Arabidopsis thaliana transcriptome analysis revealed that TATA-box-containing genes were generally those showing relatively high levels of expression and that TC-element-containing genes were generally those expressed in specific conditions. Conclusions Our observations suggest that the TC-elements might constitute a class of novel regulatory elements participating towards the complex modulation of gene expression in plants.

  20. Activation of Plant Innate Immunity by Extracellular High Mobility Group Box 3 and Its Inhibition by Salicylic Acid.

    Directory of Open Access Journals (Sweden)

    Hyong Woo Choi

    2016-03-01

    Full Text Available Damage-associated molecular pattern molecules (DAMPs signal the presence of tissue damage to induce immune responses in plants and animals. Here, we report that High Mobility Group Box 3 (HMGB3 is a novel plant DAMP. Extracellular HMGB3, through receptor-like kinases BAK1 and BKK1, induced hallmark innate immune responses, including i MAPK activation, ii defense-related gene expression, iii callose deposition, and iv enhanced resistance to Botrytis cinerea. Infection by necrotrophic B. cinerea released HMGB3 into the extracellular space (apoplast. Silencing HMGBs enhanced susceptibility to B. cinerea, while HMGB3 injection into apoplast restored resistance. Like its human counterpart, HMGB3 binds salicylic acid (SA, which results in inhibition of its DAMP activity. An SA-binding site mutant of HMGB3 retained its DAMP activity, which was no longer inhibited by SA, consistent with its reduced SA-binding activity. These results provide cross-kingdom evidence that HMGB proteins function as DAMPs and that SA is their conserved inhibitor.

  1. ASTROCULTURE(tm) Commercial Plant Growth Unit and Glove Box Insert

    Science.gov (United States)

    Zhou, Wei-Jia; Lambing, Steve (Technical Monitor)

    2002-01-01

    Two commercial plant investigations will be conducted during the STS-107 mission: living flower essential oil production and gene transfer. The research will be done using the ASTROCULTURE (trademark) hardware, which builds on similar experiments flown in the past on the space shuttle. This research will investigate how microgravity might affect the formation of the volatile chemical compounds - the essential oils - produced by two different types of living flowers. The flowers will be cultured in the ASTROCULTURE (trademark) plant chamber, which provides an enclosed and controlled environment. As the flowers bloom in space, they will produce essential oils, and these volatile compounds will be collected using International Flavors and Fragrance's proprietary Solid Phase Micro Extraction (SPME) technology. The gene transfer experiment examines a newly developed transformation system to see if it operates efficiently in the microgravity environment. This research is important for the development of genetically engineered crops, also known as transgenic crops.

  2. Virtual box

    DEFF Research Database (Denmark)

    Stougaard, Malthe Kirkhoff

    2007-01-01

    . This paper reports on the design, implementation and initial evaluation of Virtual Box. Virtual Box attempts to create a physical and engaging context in order to support reciprocal interactions with expressive content. An implemented version of Virtual Box is evaluated in a location-aware environment...

  3. Fear and loathing at a combined cycle power plant - ion chromatography in a box

    Energy Technology Data Exchange (ETDEWEB)

    Newton, B.; Doyle, M. [Dionex Corporation, Sunnyvale, CA (United States); Carvalho, L.; Scarth, I. [GE Water and Process Technologies, Mississauga, ON (Canada); Lindau, P.

    2005-06-01

    The use of ion chromatography for monitoring corrosive ions in water has been implemented at several new combined cycle gas-fired power plants. Due to stringent requirements for clean water to prevent corrosion and plugging of turbine components, this methodology is predicted to have a significant impact in extending useful operating lifetimes and to measurably increase the availability of components in contact with water. Ion chromatography, due to its ability to identify individual anion and cation species, to achieve parts-per-trillion detection limits, and to operate on-line, has played a central role in the effectiveness of these water chemistry monitoring programs. Combined cycle power plants are faced with tough choices for water monitoring. The lack of trained chemists to run low level analyses results in uncertainty as to the quality of the water used for steam going to the turbine and in some cases to the generator. This paper presents a report on a recent study of a low cost, hands-off ion chromatography solution to provide on-line monitoring at the water panel for chloride and sulfate ions at 1 part per billion or below. (orig.)

  4. Ovule-specific MADS box proteins have conserved protein-protein interactions in monocots and dicot plants

    NARCIS (Netherlands)

    Favaro, R.; Immink, R.G.H.; Ferioli, V.; Bernasconi, B.; Byzova, M.; Angenent, G.C.; Kater, M.; Colombo, L.

    2002-01-01

    OsMADS13 is a rice MADS-box gene that is specifically expressed in developing ovules. The amino acid sequence of OsMADS13 shows 74␜imilarity to those of FLORAL BINDING PROTEIN 7 (FBP7) and FBP11, the products of two MADS-box genes that are necessary and sufficient to determine ovule identity in

  5. The VirD2 pilot protein of Agrobacterium-transferred DNA interacts with the TATA box-binding protein and a nuclear protein kinase in plants.

    Science.gov (United States)

    Bakó, László; Umeda, Masaaki; Tiburcio, Antonio F; Schell, Jeff; Koncz, Csaba

    2003-08-19

    The bacterial virulence protein VirD2 plays an important role in nuclear import and chromosomal integration of Agrobacterium-transferred DNA in fungal, plant, animal, and human cells. Here we show that in nuclei of alfalfa cells, VirD2 interacts with and is phosphorylated by CAK2Ms, a conserved plant ortholog of cyclin-dependent kinase-activating kinases. CAK2Ms binds to and phosphorylates the C-terminal regulatory domain of RNA polymerase II largest subunit, which can recruit the TATA box-binding protein. VirD2 is found in tight association with the TATA box-binding protein in vivo. These results indicate that recognition of VirD2 is mediated by widely conserved nuclear factors in eukaryotes.

  6. Bento Boxes

    Science.gov (United States)

    Hasio, Cindy

    2010-01-01

    Bento boxes are common objects in Japanese culture, designed to hold enough lunch for one person. They have individual compartments and sometimes multiple tiers for rice, vegetables, and other side dishes. They are made of materials ranging from wood, cloth, aluminum, or plastic. In general, the greater the number of foods, the better the box is…

  7. Synchronization of cytoplasmic and transferred mitochondrial ribosomal protein gene expression in land plants is linked to Telo-box motif enrichment

    Directory of Open Access Journals (Sweden)

    Zhu Xin-Guang

    2011-06-01

    Full Text Available Abstract Background Chloroplasts and mitochondria evolved from the endosymbionts of once free-living eubacteria, and they transferred most of their genes to the host nuclear genome during evolution. The mechanisms used by plants to coordinate the expression of such transferred genes, as well as other genes in the host nuclear genome, are still poorly understood. Results In this paper, we use nuclear-encoded chloroplast (cpRPGs, as well as mitochondrial (mtRPGs and cytoplasmic (euRPGs ribosomal protein genes to study the coordination of gene expression between organelles and the host. Results show that the mtRPGs, but not the cpRPGs, exhibit strongly synchronized expression with euRPGs in all investigated land plants and that this phenomenon is linked to the presence of a telo-box DNA motif in the promoter regions of mtRPGs and euRPGs. This motif is also enriched in the promoter regions of genes involved in DNA replication. Sequence analysis further indicates that mtRPGs, in contrast to cpRPGs, acquired telo-box from the host nuclear genome. Conclusions Based on our results, we propose a model of plant nuclear genome evolution where coordination of activities in mitochondria and chloroplast and other cellular functions, including cell cycle, might have served as a strong selection pressure for the differential acquisition of telo-box between mtRPGs and cpRPGs. This research also highlights the significance of physiological needs in shaping transcriptional regulatory evolution.

  8. Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins.

    Science.gov (United States)

    Li, Man-Wah; Zhou, Liang; Lam, Hon-Ming

    2015-01-01

    Arabidopsis High Mobility Group Box (HMBG) proteins were previously found associated with the interphase chromatin but not the metaphase chromosome. However, these studies are usually based on immunolocalization analysis involving paraformaldehyde fixation. Paraformaldehyde fixation has been widely adapted to preserved cell morphology before immunofluorescence staining. On one hand, the processed cells are no longer living. On the other hand, the processing may lead to misinterpretation of localization. HMGBs from Arabidopsis were fused with enhanced green fluorescence protein (EGFP) and transformed into tobacco BY-2 cells. Basically, the localization of these HMGB proteins detected with EGFP fluorescence in interphase agreed with previous publications. Upon 4% paraformaldehyde fixation, AtHMGB1 was found associated with interphase but not the metaphase chromosomes as previously reported. However, when EGFP fluorescence signal was directly observed under confocal microscope without fixation, association of AtHMGB1 with metaphase chromosomes can be detected. Paraformaldehyde fixation led to dissociation of EGFP tagged AtHMBG1 protein from metaphase chromosomes. This kind of pre-processing of live specimen may lead to dissociation of protein-protein or protein-nucleic acid interaction. Therefore, using of EGFP fusion proteins in live specimen is a better way to determine the correct localization and interaction of proteins.

  9. Arabidopsis root initiation defective1, a DEAH-box RNA helicase involved in pre-mRNA splicing, is essential for plant development.

    Science.gov (United States)

    Ohtani, Misato; Demura, Taku; Sugiyama, Munetaka

    2013-06-01

    Pre-mRNA splicing is a critical process in gene expression in eukaryotic cells. A multitude of proteins are known to be involved in pre-mRNA splicing in plants; however, the physiological roles of only some of these have been examined. Here, we investigated the developmental roles of a pre-mRNA splicing factor by analyzing root initiation defective1-1 (rid1-1), an Arabidopsis thaliana mutant previously shown to have severe defects in hypocotyl dedifferentiation and de novo meristem formation in tissue culture under high-temperature conditions. Phenotypic analysis in planta indicated that RID1 is differentially required during development and has roles in processes such as meristem maintenance, leaf morphogenesis, and root morphogenesis. RID1 was identified as encoding a DEAH-box RNA helicase implicated in pre-mRNA splicing. Transient expression analysis using intron-containing reporter genes showed that pre-mRNA splicing efficiency was affected by the rid1 mutation, which supported the presumed function of RID1 in pre-mRNA splicing. Our results collectively suggest that robust levels of pre-mRNA splicing are critical for several specific aspects of plant development.

  10. A black-box model for generation of site-specific WWTP influent quality data based on plant routine data.

    Science.gov (United States)

    Ahnert, Markus; Marx, Conrad; Krebs, Peter; Kuehn, Volker

    2016-12-01

    This paper presents a simple method for the generation of continuous influent quality datasets for wastewater treatment plants (WWTPs) that is based on incomplete available routine data, only, without referring to any further measurement. In the approach, Weibull-distributed random data are fitted to the available routine data, such that the resulting distribution of influent quality data shows the identical statistical characteristics. Beside the description of the method, this paper contains a comprehensive analysis of robustness and universality of the approach. It is shown that incomplete datasets with only 10% remaining influent quality data can be filled with this method with nearly the same statistical parameters as the original data. In addition, the use with datasets of different WWTP plants sizes results always in a good agreement between original and filled datasets.

  11. BjMYB1, a transcription factor implicated in plant defence through activating BjCHI1 chitinase expression by binding to a W-box-like element.

    Science.gov (United States)

    Gao, Ying; Jia, Shuangwei; Wang, Chunlian; Wang, Fujun; Wang, Fajun; Zhao, Kaijun

    2016-08-01

    We previously identified the W-box-like-4 (Wbl-4) element (GTAGTGACTCAT), one of six Wbl elements in the BjC-P promoter of the unusual chitinase gene BjCHI1 from Brassica juncea, as the core element responsive to fungal infection. Here, we report the isolation and characterization of the cognate transcription factor interacting with the Wbl-4 element. Using Wbl-4 as a target, we performed yeast one-hybrid screening of a B. juncea cDNA library and isolated an R2R3-MYB transcription factor designated as BjMYB1. BjMYB1 was localized in the nucleus of plant cells. EMSA assays confirmed that BjMYB1 binds to the Wbl-4 element. Transiently expressed BjMYB1 up-regulated the activity of the BjC-P promoter through its binding to the Wbl-4 element in tobacco (Nicotiana benthamiana) leaves. In B. juncea, BjMYB1 displayed a similar induced expression pattern as that of BjCHI1 upon infection by the fungus Botrytis cinerea Moreover, heterogeneous overexpression of BjMYB1 significantly elevated the resistance of transgenic Arabidopsis thaliana to the fungus B. cinerea These results suggest that BjMYB1 is potentially involved in host defence against fungal attack through activating the expression of BjCHI1 by binding to the Wbl-4 element in the BjC-P promoter. This finding demonstrates a novel DNA target of plant MYB transcription factors. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  12. Stress-inducible expression of an F-box gene TaFBA1 from wheat enhanced the drought tolerance in transgenic tobacco plants without impacting growth and development

    Directory of Open Access Journals (Sweden)

    Xiangzhu Kong

    2016-09-01

    Full Text Available E3 ligase plays an important role in the response to many environment stresses in plants. In our previous study, constitutive overexpression of an F-box protein gene TaFBA1 driven by 35S promoter improved the drought tolerance in transgenic tobacco plants, but the growth and development in transgenic plants was altered in normal conditions. In this study, we used stress-inducible promoter RD29A instead of 35S promoter, as a results, the stress-inducible transgenic tobacco plants exhibit a similar phenotype with WT plants. However, the drought tolerance of the transgenic plants with stress-inducible expressed TaFBA1 was enhanced. The improved drought tolerance of transgenic plants was indicated by their higher seed germination rate and survival rate, greater biomass and photosynthesis than those of WT under water stress, which may be related to their greater water retention capability and osmotic adjustment. Moreover, the transgenic plants accumulated less reactive oxygen species (ROS, kept lower MDA content and membrane leakage under water stress, which may be related to their higher levels of antioxidant enzyme activity and upregulated gene expression of some antioxidant enzymes. These results suggest that stress induced expression of TaFBA1 confers drought tolerance via the improved water retention and antioxidative compete abilibty. Meanwhile, this stress-inducible expression strategy by RD29A promoter can minimize the unexpectable effects by 35S constitutive promoter on phenotypes of the transgenic plants.

  13. Shaping 3-D boxes

    DEFF Research Database (Denmark)

    Stenholt, Rasmus; Madsen, Claus B.

    2011-01-01

    Enabling users to shape 3-D boxes in immersive virtual environments is a non-trivial problem. In this paper, a new family of techniques for creating rectangular boxes of arbitrary position, orientation, and size is presented and evaluated. These new techniques are based solely on position data......F) docking experiment against an existing technique, which requires the user to perform the rotation and scaling of the box explicitly. The precision of the users' box construction is evaluated by a novel error metric measuring the difference between two boxes. The results of the experiment strongly indicate...... that for precision docking of 9 DoF boxes, some of the proposed techniques are significantly better than ones with explicit rotation and scaling. Another interesting result is that the number of DoF simultaneously controlled by the user significantly influences the precision of the docking....

  14. Math in the Box

    Science.gov (United States)

    DeYoung, Mary J.

    2009-01-01

    This article describes how to make an origami paper box and explores the algebra, geometry, and other mathematics that unfolds. A set of origami steps that transforms the paper into an open box can hold mathematical surprises for both students and teachers. An origami lesson can engage students in an open-ended exploration of the relationship…

  15. ALUMINUM BOX BUNDLING PRESS

    Directory of Open Access Journals (Sweden)

    Iosif DUMITRESCU

    2015-05-01

    Full Text Available In municipal solid waste, aluminum is the main nonferrous metal, approximately 80- 85% of the total nonferrous metals. The income per ton gained from aluminum recuperation is 20 times higher than from glass, steel boxes or paper recuperation. The object of this paper is the design of a 300 kN press for aluminum box bundling.

  16. BoxPlot++

    OpenAIRE

    Azmeh, Zeina; Hamoui, Fady; Huchard, Marianne

    2011-01-01

    We propose the BoxPlot++ as an extension of Tukey's boxplot. We improve the resulting data values distribution by removing the repeated values and by calculating distances between the points and the nearest median.

  17. Boxes and Shelves

    OpenAIRE

    Hughes, Dean

    2008-01-01

    The Boxes and Shelves series from 2008 are are all made from the backing card from discarded writing pads. Boxes and Shelves extended my investigation of quotidian materials and their relationship to the origins of creative toil. Since 1996 my research has sought to identify and locate instances where the 'unmeasurable' meets the measurable. I have consistently employed a range of utilitarian materials such as bus seats, bus tickets, puddles, A4 writing paper, to present a series of 'problem ...

  18. Freedom to box.

    Science.gov (United States)

    Warburton, N

    1998-02-01

    The british Medical Association wants to criminalise all boxing. This article examines the logic of the arguments it uses and finds them wanting. The move from medical evidence about the risk of brain damage to the conclusion that boxing should be banned is not warranted. The BMA's arguments are a combination of inconsistent paternalism and legal moralism. Consistent application of the principles implicit in the BMA's arguments would lead to absurd consequences and to severe limitations being put on individual freedom.

  19. Analysis of the petunia MADS-box transcription factor family

    NARCIS (Netherlands)

    Immink, R.G.H.; Ferrario, S.I.T.; Busscher-Lange, J.; Kooiker, M.; Busscher, M.; Angenent, G.C.

    2003-01-01

    Transcription factors are key regulators of plant development. One of the major groups of transcription factors is the MADS-box family, of which at least 80 members are encoded in the Arabidopsis genome. In this study, 23 members of the petunia MADS-box transcription factor family were investigated

  20. Cable Tester Box

    Science.gov (United States)

    Lee, Jason H.

    2011-01-01

    Cables are very important electrical devices that carry power and signals across multiple instruments. Any fault in a cable can easily result in a catastrophic outcome. Therefore, verifying that all cables are built to spec is a very important part of Electrical Integration Procedures. Currently, there are two methods used in lab for verifying cable connectivity. (1) Using a Break-Out Box and an ohmmeter this method is time-consuming but effective for custom cables and (2) Commercial Automated Cable Tester Boxes this method is fast, but to test custom cables often requires pre-programmed configuration files, and cables used on spacecraft are often uniquely designed for specific purposes. The idea is to develop a semi-automatic continuity tester that reduces human effort in cable testing, speeds up the electrical integration process, and ensures system safety. The JPL-Cable Tester Box is developed to check every single possible electrical connection in a cable in parallel. This system indicates connectivity through LED (light emitting diode) circuits. Users can choose to test any pin/shell (test node) with a single push of a button, and any other nodes that are shorted to the test node, even if they are in the same connector, will light up with the test node. The JPL-Cable Tester Boxes offers the following advantages: 1. Easy to use: The architecture is simple enough that it only takes 5 minutes for anyone to learn how operate the Cable Tester Box. No pre-programming and calibration are required, since this box only checks continuity. 2. Fast: The cable tester box checks all the possible electrical connections in parallel at a push of a button. If a cable normally takes half an hour to test, using the Cable Tester Box will improve the speed to as little as 60 seconds to complete. 3. Versatile: Multiple cable tester boxes can be used together. As long as all the boxes share the same electrical potential, any number of connectors can be tested together.

  1. Phytoplasma Effector SAP54 Hijacks Plant Reproduction by Degrading MADS-box Proteins and Promotes Insect Colonization in a RAD23-Dependent Manner

    Science.gov (United States)

    MacLean, Allyson M.; Orlovskis, Zigmunds; Kowitwanich, Krissana; Zdziarska, Anna M.; Angenent, Gerco C.; Immink, Richard G. H.; Hogenhout, Saskia A.

    2014-01-01

    Pathogens that rely upon multiple hosts to complete their life cycles often modify behavior and development of these hosts to coerce them into improving pathogen fitness. However, few studies describe mechanisms underlying host coercion. In this study, we elucidate the mechanism by which an insect-transmitted pathogen of plants alters floral development to convert flowers into vegetative tissues. We find that phytoplasma produce a novel effector protein (SAP54) that interacts with members of the MADS-domain transcription factor (MTF) family, including key regulators SEPALLATA3 and APETALA1, that occupy central positions in the regulation of floral development. SAP54 mediates degradation of MTFs by interacting with proteins of the RADIATION SENSITIVE23 (RAD23) family, eukaryotic proteins that shuttle substrates to the proteasome. Arabidopsis rad23 mutants do not show conversion of flowers into leaf-like tissues in the presence of SAP54 and during phytoplasma infection, emphasizing the importance of RAD23 to the activity of SAP54. Remarkably, plants with SAP54-induced leaf-like flowers are more attractive for colonization by phytoplasma leafhopper vectors and this colonization preference is dependent on RAD23. An effector that targets and suppresses flowering while simultaneously promoting insect herbivore colonization is unprecedented. Moreover, RAD23 proteins have, to our knowledge, no known roles in flower development, nor plant defence mechanisms against insects. Thus SAP54 generates a short circuit between two key pathways of the host to alter development, resulting in sterile plants, and promotes attractiveness of these plants to leafhopper vectors helping the obligate phytoplasmas reproduce and propagate (zombie plants). PMID:24714165

  2. Phytoplasma effector SAP54 hijacks plant reproduction by degrading MADS-box proteins and promotes insect colonization in a RAD23-dependent manner.

    Directory of Open Access Journals (Sweden)

    Allyson M MacLean

    2014-04-01

    Full Text Available Pathogens that rely upon multiple hosts to complete their life cycles often modify behavior and development of these hosts to coerce them into improving pathogen fitness. However, few studies describe mechanisms underlying host coercion. In this study, we elucidate the mechanism by which an insect-transmitted pathogen of plants alters floral development to convert flowers into vegetative tissues. We find that phytoplasma produce a novel effector protein (SAP54 that interacts with members of the MADS-domain transcription factor (MTF family, including key regulators SEPALLATA3 and APETALA1, that occupy central positions in the regulation of floral development. SAP54 mediates degradation of MTFs by interacting with proteins of the RADIATION SENSITIVE23 (RAD23 family, eukaryotic proteins that shuttle substrates to the proteasome. Arabidopsis rad23 mutants do not show conversion of flowers into leaf-like tissues in the presence of SAP54 and during phytoplasma infection, emphasizing the importance of RAD23 to the activity of SAP54. Remarkably, plants with SAP54-induced leaf-like flowers are more attractive for colonization by phytoplasma leafhopper vectors and this colonization preference is dependent on RAD23. An effector that targets and suppresses flowering while simultaneously promoting insect herbivore colonization is unprecedented. Moreover, RAD23 proteins have, to our knowledge, no known roles in flower development, nor plant defence mechanisms against insects. Thus SAP54 generates a short circuit between two key pathways of the host to alter development, resulting in sterile plants, and promotes attractiveness of these plants to leafhopper vectors helping the obligate phytoplasmas reproduce and propagate (zombie plants.

  3. The BOXES Methodology Black Box Dynamic Control

    CERN Document Server

    Russell, David W

    2012-01-01

    Robust control mechanisms customarily require knowledge of the system’s describing equations which may be of the high order differential type.  In order to produce these equations, mathematical models can often be derived and correlated with measured dynamic behavior.  There are two flaws in this approach one is the level of inexactness introduced by linearizations and the other when no model is apparent.  Several years ago a new genre of control systems came to light that are much less dependent on differential models such as fuzzy logic and genetic algorithms. Both of these soft computing solutions require quite considerable a priori system knowledge to create a control scheme and sometimes complicated training program before they can be implemented in a real world dynamic system. Michie and Chambers’ BOXES methodology created a black box system that was designed to control a mechanically unstable system with very little a priori system knowledge, linearization or approximation.  All the method need...

  4. Opto-Box

    CERN Document Server

    Bertsche, David; The ATLAS collaboration; Welch, Steven; Smith, Dale Shane; Che, Siinn; Gan, K.K.; Boyd, George Russell Jr

    2015-01-01

    The opto-box is a custom mini-crate for housing optical modules, which process and transfer optoelectronic data. The system tightly integrates electrical, mechanical, and thermal functionality into a small package of size 35x10x8 cm^3. Special attention was given to ensure proper shielding, grounding, cooling, high reliability, and environmental tolerance. The custom modules, which incorporate Application Specific Integrated Circuits (ASICs), were developed through a cycle of rigorous testing and redesign. In total, fourteen opto-boxes have been installed and loaded with modules on the ATLAS detector. They are currently in operation as part of the LHC run 2 data read-out chain.

  5. Phytoplasma Effector SAP54 Hijacks Plant Reproduction by Degrading MADS-box Proteins and Promotes Insect Colonization in a RAD23-Dependent Manner

    OpenAIRE

    Allyson M MacLean; Zigmunds Orlovskis; Krissana Kowitwanich; Zdziarska, Anna M.; Angenent, Gerco C.; Immink, Richard G. H.; Hogenhout, Saskia A.

    2014-01-01

    Pathogens that rely upon multiple hosts to complete their life cycles often modify behavior and development of these hosts to coerce them into improving pathogen fitness. However, few studies describe mechanisms underlying host coercion. In this study, we elucidate the mechanism by which an insect-transmitted pathogen of plants alters floral development to convert flowers into vegetative tissues. We find that phytoplasma produce a novel effector protein (SAP54) that interacts with members of ...

  6. Teaching with Box Tops.

    Science.gov (United States)

    Raiser, Lynne; D'Zamko, Mary Elizabeth

    1984-01-01

    Using environmental materials (such as the phone book and placemats from fast food restaurants) can be a motivating way to teach learning disabled students skills and concepts, as shown in an approach to reading, math, science and nutrition, and social studies instruction using a JELL-O brand gelatin box. (CL)

  7. Many-box locality

    Science.gov (United States)

    Zhou, Yuqian; Cai, Yu; Bancal, Jean-Daniel; Gao, Fei; Scarani, Valerio

    2017-11-01

    There is an ongoing search for a physical or operational definition for quantum mechanics. Several informational principles have been proposed which are satisfied by a theory less restrictive than quantum mechanics. Here, we introduce the principle of "many-box locality," which is a refined version of the previously proposed "macroscopic locality." These principles are based on coarse graining the statistics of several copies of a given box. The set of behaviors satisfying many-box locality for N boxes is denoted LNM B. We study these sets in the bipartite scenario with two binary measurements, in relation with the sets Q and Q1 +A B of quantum and "almost quantum" correlations, respectively. We find that the LNM B sets are, in general, not convex. For unbiased marginals, by working in the Fourier space we can prove analytically that LNM B⊈Q for any finite N , while L∞M B=Q . Then, with suitably developed numerical tools, we find an example of a point that belongs to L16M B but not to Q1 +A B. Among the problems that remain open is whether Q ⊂L∞M B .

  8. IN-A-BOX

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 2. Claude Elwood Shannon. Priti Shankar. Article-in-a-Box Volume 7 Issue 2 February 2002 pp 2-3. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/007/02/0002-0003. Author Affiliations.

  9. Mystery Box Marvels

    Science.gov (United States)

    Santos, Joel; Centurio, Tina

    2012-01-01

    What happens in the first week of school could very well set the stage for the rest of the school year. Setting high standards for science activities based in inquiry can start on the first day of science class and develop as the year unfolds. With the use of simple, readily available, inexpensive materials, an efficient mystery box lesson can be…

  10. Operant-Box Sociology

    Science.gov (United States)

    Dimond, Stuart J.

    1971-01-01

    Sketches a model which considers society a teacher which instructs like an operant box..." The author contends that the family, the school, the play group, the adolescent gang, the office, the prison, the mental hospital, each reward, instruct and control the individual who learns by operant means what the institution teaches." (Author/AL)

  11. Hermit Points on a Box

    Science.gov (United States)

    Hess, Richard; Grinstead, Charles; Grindstead, Marshall; Bergstrand, Deborah

    2008-01-01

    Suppose that we are given a rectangular box in 3-space. Given any two points on the surface of this box, we can define the surface distance between them to be the length of the shortest path between them on the surface of the box. This paper determines the pairs of points of maximum surface distance for all boxes. It is often the case that these…

  12. Opto-Box

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00377159; The ATLAS collaboration

    2015-01-01

    The opto-box is a custom mini-crate for housing optical modules, which process and transfer optoelectronic data. Many novel solutions were developed for the custom design and manufacturing. The system tightly integrates electrical, mechanical, and thermal functionality into a small package of size 35x10x8 cm$^{3}$. Special attention was given to ensure proper shielding, grounding, cooling, high reliability, and environmental tolerance. The custom modules, which incorporate Application Specific Integrated Circuits (ASICs), were developed through a cycle of rigorous testing and redesign. In total, fourteen opto-boxes have been installed and loaded with modules on the ATLAS detector. They are currently in operation as part of the LHC run 2 data read-out chain.

  13. Boxed Permutation Pattern Matching

    DEFF Research Database (Denmark)

    Amit, Mika; Bille, Philip; Cording, Patrick Hagge

    2016-01-01

    the goal is to only find the boxed subsequences of T that are order-isomorphic to P. This problem was introduced by Bruner and Lackner who showed that it can be solved in O(n3) time. Cho et al. [CPM 2015] gave an O(n2m) time algorithm and improved it to O(n2 logm). In this paper we present a solution...

  14. Small, Lightweight, Collapsible Glove Box

    Science.gov (United States)

    James, Jerry

    2009-01-01

    A small, lightweight, collapsible glove box enables its user to perform small experiments and other tasks. Originally intended for use aboard a space shuttle or the International Space Station (ISS), this glove box could also be attractive for use on Earth in settings in which work space or storage space is severely limited and, possibly, in which it is desirable to minimize weight. The development of this glove box was prompted by the findings that in the original space-shuttle or ISS setting, (1) it was necessary to perform small experiments in a large general-purpose work station, so that, in effect, they occupied excessive space; and it took excessive amounts of time to set up small experiments. The design of the glove box reflects the need to minimize the space occupied by experiments and the time needed to set up experiments, plus the requirement to limit the launch weight of the box and the space needed to store the box during transport into orbit. To prepare the glove box for use, the astronaut or other user has merely to insert hands through the two fabric glove ports in the side walls of the box and move two hinges to a locking vertical position (see figure). The user could do this while seated with the glove box on the user fs lap. When stowed, the glove box is flat and has approximately the thickness of two pieces of 8-in. (.20 cm) polycarbonate.

  15. Functional and evolutionary studies of type I MADS box genes in Petunia hybrida and arabidopsis thaliana

    NARCIS (Netherlands)

    Bemer, Marian

    2008-01-01

    MADS-box genes are very important for plant development and especially for the formation of the flower. The MADS box family of transcription factors in plants can be subdivided into two classes: the MIKC-type genes, which play essential roles in flower formation, and the type I genes, which are

  16. The G-Box Transcriptional Regulatory Code in Arabidopsis.

    Science.gov (United States)

    Ezer, Daphne; Shepherd, Samuel J K; Brestovitsky, Anna; Dickinson, Patrick; Cortijo, Sandra; Charoensawan, Varodom; Box, Mathew S; Biswas, Surojit; Jaeger, Katja E; Wigge, Philip A

    2017-10-01

    Plants have significantly more transcription factor (TF) families than animals and fungi, and plant TF families tend to contain more genes; these expansions are linked to adaptation to environmental stressors. Many TF family members bind to similar or identical sequence motifs, such as G-boxes (CACGTG), so it is difficult to predict regulatory relationships. We determined that the flanking sequences near G-boxes help determine in vitro specificity but that this is insufficient to predict the transcription pattern of genes near G-boxes. Therefore, we constructed a gene regulatory network that identifies the set of bZIPs and bHLHs that are most predictive of the expression of genes downstream of perfect G-boxes. This network accurately predicts transcriptional patterns and reconstructs known regulatory subnetworks. Finally, we present Ara-BOX-cis (araboxcis.org), a Web site that provides interactive visualizations of the G-box regulatory network, a useful resource for generating predictions for gene regulatory relations. © 2017 American Society of Plant Biologists. All Rights Reserved.

  17. Spirit Boxes: Expressions of Culture.

    Science.gov (United States)

    DeMuro, Ted

    1984-01-01

    After studying the culture and art of the ancient civilizations of South America, Mesopotamia, Greece, and Egypt, secondary level art students made spirit boxes as expressions of the various cultures. How to make the boxes and how to prepare the face molds are described. (RM)

  18. Being Creative "Inside the Box"

    Science.gov (United States)

    Tomascoff, Rocky

    2011-01-01

    Artist Joseph Cornell (1903-1972) created wonderful environments inside boxes using mostly found objects. They were often Surrealistic in nature. Some boxes were designed with glass fronts, and others were meant to be interactive with the viewer, wherein the objects could be handled. With Joseph Cornell in mind, the author introduces an art…

  19. Box-and-Whisker Plots.

    Science.gov (United States)

    Larsen, Russell D.

    1985-01-01

    Box-and-whisker plots (which give rapid visualization of batches of data) can be effectively used to present diverse collections of data used in traditional first-year chemistry courses. Construction of box-and-whisker plots and their use with bond energy data and data on heats of formation and solution are discussed. (JN)

  20. Do Biomimetic Students Think Outside the Box?

    DEFF Research Database (Denmark)

    Lenau, Torben Anker

    2017-01-01

    Biomimetics is a recognized method in ideation for getting access to new and – for the designer – novel knowledge, which hopefully will result in more novel and useful products. But do designers actually find new knowledge, i.e. think outside the box or do they stick to well-known biological...... phenomena? If they concentrate on animals and plants, which they beforehand have knowledge about, it could be expected that solutions will remind of what they would have found without using biomimetics. To investigate this question, the empirical results from a university course in biomimetics have been...

  1. Microclimate boxes for panel paintings

    DEFF Research Database (Denmark)

    Wadum, Jørgen

    1998-01-01

    The use of microclimate boxes to protect vulnerable panel paintings is, therefore, not a new phenomenon of the past two or three decades. Rather, it has been a concern for conservators and curators to protect these objects of art at home and in transit since the end of the nineteenth century....... The increased number of travelling exhibitions in recent years has heightened the need to protect paintings during circulation (Thomson 1961; Mecklenburg 1991). The use and design of microclimate boxes have been evolving since 1892. These boxes may be divided into three broad groups: those using an active...

  2. Two-dimensional box plot

    OpenAIRE

    Phattrawan Tongkumchum

    2005-01-01

    In this paper we propose a two-dimensional box plot, a simple bivariate extension of the box plot and the scatter plot. This plot comprises a pair of trapeziums oriented in the direction of a fitted straight line, with symbols denoting extreme values. The choice for the fitted straight resistant line showing the relationship between the two variables is Tukey’s resistance line. The main components of the plot are an inner box containing 50% of the projection points of the observations on the ...

  3. DIRECT KICKS IN BOXING

    Directory of Open Access Journals (Sweden)

    Izet Kahrović

    2009-11-01

    Full Text Available Hit directly, giving any impact maximum muscle strength is skill, and it is neces- sary to the exercise and learning to make it perfect. Training begins with oral statement, so that students get to know with the techni- que that works. After oral exposure, it is necessary to create a good notion on technology that is adopted. The best way for the creation of good notion is a good demonstration. In direct training kicks in the box, you need patience and gradualness and there- fore uses a large number of additional exercises. In their work with beginners, in the first class, individual elements of technology, and also direct blow, it is necessary to separate the parts and run them on multiple commands, to later come to the confluence in one command. Direct wounds, with left and right hand, can be run from the towns, on the head and body, from the movement, to step forward, step back and step aside, the remedy to the left and right side. Left direct is taking out from a running protrusion hands, but kick, which is a pro- duct of the system, ankle-knee-pelvis and shoulder forward horizontaly. Set at the time of stripes, body weight over the left leg. Right direct from the place, starting ekscentrical reflecsive impuls of a extensor muscle in ankle, knee and joint of a hip.This kind of a sud- den movement is running simultaneously with the rotation of the body around vertical (longitudinal axis, with the transfer body weight on the left leg. Further movement to the hand which serves as a lever, which is transmitted through the power stroke

  4. Box Plots: Basic and Advanced.

    Science.gov (United States)

    Mullenex, James L.

    1990-01-01

    Describes a five-number summary which is a display of the minimum value, lower quartile, median, upper quartile, and maximum value. Indicates how to draw box plots as graphical representations of a five-number summary. (YP)

  5. Implementace hry Dots and Boxes

    OpenAIRE

    Balko, Martin

    2010-01-01

    Title: Dots and Boxes implementation Author: Martin Balko Department: Department of Applied Mathematics Supervisor: RNDr. Ondřej Pangrác, Ph.D. Supervisor's email address: Abstract: The presented thesis deals with the analysis of a popular logical game Dots and Boxes and its generalized versions. It focuses on the different methods and algorithms of opponent's artificial intelligence. The result of the work is implementation of the generalized version of this game in w...

  6. Cloning and expression analysis of an E-class MADS-box gene from ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-05

    Oct 5, 2009 ... 38: 484-489. Sung SK, Yu GH, Nam J, Jeong DH, An G (2000). Developmentally regulated expression of two MADS-box genes, MdMADS3 and. MdMADS4, in the morphogenesis of flower buds and fruits in apple. Planta, 210: 519-528. Theissen G, Saedler H (1995). MADS-box genes in plant ontogeny and.

  7. Thinking Outside the Box

    Energy Technology Data Exchange (ETDEWEB)

    Green, Lorne [World Nuclear Transport Institute, Remo House, 310-312 Regent Street, London, W1B 3AX (United Kingdom)

    2009-06-15

    The World Nuclear Transport Institute was formed to fill a need to provide a dedicated vehicle for the radioactive transport and packaging industry sectors worldwide, to exchange information and ideas, all with a view to working toward consolidated industry positions on the key issues affecting safe, efficient and reliable transport. WNTI was also intended to be a strong voice for industry in those international and national bodies where deliberations on such transport safety issues take place. The very fact that companies, sometimes in competition with each other, were prepared to come together in this way, reflects two important points: firstly, it represents an acknowledgement on industry's part that safe, effective and reliable transport is the sine qua non, the absolute essential. And second, it is a recognition that it is enhanced to the extent that industry is able to collaborate to this end. This is thinking outside the box. Another important attribute of safety is 'stability'. Everyone likes to know where he or she stands. The radioactive materials packaging and transport industry thrives within a stable regulatory framework for safety. For a stable regulatory regime allows operators to be properly trained; it allows operators to become familiar with safety requirements, and to be at ease with them. Stability is conducive to safety and efficiency. Stability is good for business too - for stability in package and transport requirements allows sufficient time for a fair return on investment in expensive package design, manufacture, licensing and use over time. Stability should not, however, be opposed to creativity. From experience we can develop new thinking to improve efficiency as illustrated in examples of work related to the packaging and transport of Uranium Concentrates for instance.. Another example is work within WNTI on the thermal test requirements for the packaging of uranium hexafluoride. The robustness of packages is based on the

  8. Comparison of black-box, glass-box and open-box software for aiding conceptual understanding

    OpenAIRE

    Hosein, Anesa; Aczel, James; Clow, Doug; Richardson, John T E

    2008-01-01

    Three mathematical software types: black-box (no steps shown), glass-box (steps shown) and open-box (interactive steps) were used by 32 students to solve conceptual and procedural tasks on the computer via remote observation. Comparison of the three software types suggests that there is no difference in the scores that students receive for conceptual understanding tasks. Students using the black-box are more likely to explore answers than students using the glass and open-box software.

  9. 30 CFR 56.12006 - Distribution boxes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Distribution boxes. 56.12006 Section 56.12006... Distribution boxes. Distribution boxes shall be provided with a disconnecting device for each branch circuit... visual observation when such a device is open and that the circuit is deenergized, the distribution box...

  10. 30 CFR 57.12006 - Distribution boxes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Distribution boxes. 57.12006 Section 57.12006... and Underground § 57.12006 Distribution boxes. Distribution boxes shall be provided with a... deenergized, and the distribution box shall be labeled to show which circuit each device controls. ...

  11. Genome-wide identification and analysis of the MADS-box gene family in sesame.

    Science.gov (United States)

    Wei, Xin; Wang, Linhai; Yu, Jingyin; Zhang, Yanxin; Li, Donghua; Zhang, Xiurong

    2015-09-10

    MADS-box genes encode transcription factors that play crucial roles in plant growth and development. Sesame (Sesamum indicum L.) is an oil crop that contributes to the daily oil and protein requirements of almost half of the world's population; therefore, a genome-wide analysis of the MADS-box gene family is needed. Fifty-seven MADS-box genes were identified from 14 linkage groups of the sesame genome. Analysis of phylogenetic relationships with Arabidopsis thaliana, Utricularia gibba and Solanum lycopersicum MADS-box genes was performed. Sesame MADS-box genes were clustered into four groups: 28 MIKC(c)-type, 5 MIKC(⁎)-type, 14 Mα-type and 10 Mγ-type. Gene structure analysis revealed from 1 to 22 exons of sesame MADS-box genes. The number of exons in type II MADS-box genes greatly exceeded the number in type I genes. Motif distribution analysis of sesame MADS-box genes also indicated that type II MADS-box genes contained more motifs than type I genes. These results suggested that type II sesame MADS-box genes had more complex structures. By analyzing expression profiles of MADS-box genes in seven sesame transcriptomes, we determined that MIKC(C)-type MADS-box genes played significant roles in sesame flower and seed development. Although most MADS-box genes in the same clade showed similar expression features, some gene functions were diversified from the orthologous Arabidopsis genes. This research will contribute to uncovering the role of MADS-box genes in sesame development. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. Genome-wide analysis of the SBP-box gene family in Chinese cabbage (Brassica rapa subsp. pekinensis).

    Science.gov (United States)

    Tan, Hua-Wei; Song, Xiao-Ming; Duan, Wei-Ke; Wang, Yan; Hou, Xi-Lin

    2015-11-01

    The SQUAMOSA PROMOTER BINDING PROTEIN (SBP)-box gene family contains highly conserved plant-specific transcription factors that play an important role in plant development, especially in flowering. Chinese cabbage (Brassica rapa subsp. pekinensis) is a leafy vegetable grown worldwide and is used as a model crop for research in genome duplication. The present study aimed to characterize the SBP-box transcription factor genes in Chinese cabbage. Twenty-nine SBP-box genes were identified in the Chinese cabbage genome and classified into six groups. We identified 23 orthologous and 5 co-orthologous SBP-box gene pairs between Chinese cabbage and Arabidopsis. An interaction network among these genes was constructed. Sixteen SBP-box genes were expressed more abundantly in flowers than in other tissues, suggesting their involvement in flowering. We show that the MiR156/157 family members may regulate the coding regions or 3'-UTR regions of Chinese cabbage SBP-box genes. As SBP-box genes were found to potentially participate in some plant development pathways, quantitative real-time PCR analysis was performed and showed that Chinese cabbage SBP-box genes were also sensitive to the exogenous hormones methyl jasmonic acid and salicylic acid. The SBP-box genes have undergone gene duplication and loss, evolving a more refined regulation for diverse stimulation in plant tissues. Our comprehensive genome-wide analysis provides insights into the SBP-box gene family of Chinese cabbage.

  13. First-aid boxes - Reminder

    CERN Multimedia

    GS Department

    2010-01-01

    With a view to ensuring optimum use of the first-aid boxes on the CERN site, we should like to remind you of various changes introduced in March 2009: The TSO of the buildings concerned is responsible for the first-aid boxes, including checking their contents.   First-aid boxes may be restocked ONLY at the CERN stores (SCEM No. 54.99.80). This is no longer possible at the Infirmary. The associated cost is charged to the Departments.   First-aid boxes should be used only for mild injuries. All other cases should be referred to the Medical Service Infirmary (Bldg. 57 – ground-floor, tel. 73802) between 8.00 a.m. and 5.30 p.m. or to the Fire and Rescue Service (tel. 74444). N.B.: This information does not apply to the red emergency first-aid boxes in the underground areas or to the emergency kits for use in the event of being splashed with hydrofluoric acid.

  14. Identifying competencies of boxing coaches

    Directory of Open Access Journals (Sweden)

    Ioannis Tasiopoulos

    2014-10-01

    Full Text Available The purpose of this study was to find out the management skills required by boxing coaches to administrate their clubs. For the purposes of this study a scale was constructed which was answered by 98 boxing coaches. Explanatory factor analysis revealed seven factors: Communication-public relations (5 items, event management (4 items, management techniques (4 items, new technologies (4 items, prevention-safety (2 items, sport (5 items and sports facilities (2 items. The Cronbach of the scale was 0.85. The five competencies that rated by the coaches were: Supervisors of the area of training, maintaining excellent communication with athletes, using new technologies (e-mail, internet, handling disciplinary matters, accidents, complaints and reports on some sporting games and promoted harmony among athletes. We concluded that boxing coaches understand that the competencies required for meeting their obligations, were related to sports, prevention, safety and communications-public relations.

  15. Software sensors based on the grey-box modelling approach

    DEFF Research Database (Denmark)

    Carstensen, J.; Harremoës, P.; Strube, Rune

    1996-01-01

    -box model for the specific dynamics is identified. Similarly, an on-line software sensor for detecting the occurrence of backwater phenomena can be developed by comparing the dynamics of a flow measurement with a nearby level measurement. For treatment plants it is found that grey-box models applied to on......-line measurements. With respect to the development of software sensors, the grey-box models possess two important features. Firstly, the on-line measurements can be filtered according to the grey-box model in order to remove noise deriving from the measuring equipment and controlling devices. Secondly, the grey......-box models may contain terms which can be estimated on-line by use of the models and measurements. In this paper, it is demonstrated that many storage basins in sewer systems can be used as an on-line flow measurement provided that the basin is monitored on-line with a level transmitter and that a grey...

  16. Expo-Box Contact Us

    Science.gov (United States)

    EPA-Expo-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases, mode

  17. On the Dirichlet's Box Principle

    Science.gov (United States)

    Poon, Kin-Keung; Shiu, Wai-Chee

    2008-01-01

    In this note, we will focus on several applications on the Dirichlet's box principle in Discrete Mathematics lesson and number theory lesson. In addition, the main result is an innovative game on a triangular board developed by the authors. The game has been used in teaching and learning mathematics in Discrete Mathematics and some high schools in…

  18. The Bird Box Survey Project

    Science.gov (United States)

    Willis, Patrick

    2014-01-01

    When high school students are asked what's the best part of science class, many will say it's the field trips. Students enjoy engaging in authentic, community-based science outside the classroom. To capitalize on this, Patrick Willis created the Bird Box Survey Project for his introductory field biology class. The project takes students…

  19. Light Therapy Boxes for Seasonal Affective Disorder

    Science.gov (United States)

    Seasonal affective disorder treatment: Choosing a light therapy box Light therapy boxes can offer an effective treatment for seasonal affective disorder. Features such as light intensity, safety, cost and ...

  20. Main: BOX2PSGS2 [PLACE

    Lifescience Database Archive (English)

    Full Text Available BOX2PSGS2 S000204 17-May-1998 (last modified) kehi Box 2 in glutamine synthetase (G...S2) gene in pea (P.s.); Repeated in tandem with a partial palindrome located between the repeats; Located at ca. -300 of pea GS2; Box

  1. The Heuristic Interpretation of Box Plots

    Science.gov (United States)

    Lem, Stephanie; Onghena, Patrick; Verschaffel, Lieven; Van Dooren, Wim

    2013-01-01

    Box plots are frequently used, but are often misinterpreted by students. Especially the area of the box in box plots is often misinterpreted as representing number or proportion of observations, while it actually represents their density. In a first study, reaction time evidence was used to test whether heuristic reasoning underlies this…

  2. F-box genes: Genome-wide expansion, evolution and their contribution to pollen growth in pear (Pyrus bretschneideri).

    Science.gov (United States)

    Wang, Guo-Ming; Yin, Hao; Qiao, Xin; Tan, Xu; Gu, Chao; Wang, Bao-Hua; Cheng, Rui; Wang, Ying-Zhen; Zhang, Shao-Ling

    2016-12-01

    F-box gene family, as one of the largest gene families in plants, plays crucial roles in regulating plant development, reproduction, cellular protein degradation and responses to biotic and abiotic stresses. However, comprehensive analysis of the F-box gene family in pear (Pyrus bretschneideri Rehd.) and other Rosaceae species has not been reported yet. Herein, we identified a total of 226 full-length F-box genes in pear for the first time. And these genes were further divided into various subgroups based on specific domains and phylogenetic analysis. Intriguingly, we observed that whole-genome duplication and dispersed duplication have a major contribution to F-box family expansion. Furthermore, the dynamic evolution for different modes of gene duplication was dissected. Interestingly, we found that dispersed and tandem duplicate have been evolving at a high rate. In addition, we found that F-box genes exhibited functional specificity based on GO analysis, and most of the F-box genes were significantly enriched in the protein binding (GO: 0005515) term, supporting that F-box genes might play a critical role for gene regulation in pear. Transcriptome and digital expression profiles revealed that F-box genes are involved in the development of multiple pear tissues. Overall, these results will set stage for elaborating the biological role of F-box genes in pear and other plants. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  3. MADS-box gene family in rice: genome-wide identification, organization and expression profiling during reproductive development and stress

    National Research Council Canada - National Science Library

    Arora, Rita; Agarwal, Pinky; Ray, Swatismita; Singh, Ashok Kumar; Singh, Vijay Pal; Tyagi, Akhilesh K; Kapoor, Sanjay

    2007-01-01

    .... In recent years, there have been reports on genomic localization, protein motif structure, phylogenetic relationships, gene structure and expression of the entire MADS-box family in the model plant system, Arabidopsis...

  4. Lessons from the light-cone box

    CERN Document Server

    Leibbrandt, G

    2000-01-01

    Working in the noncovariant light-cone gauge, we discuss the explicit computation of the 1PI four-point function ("box diagram") in Yang- Mills theory. The complete box diagram which consists of 16 box subdiagrams, 8 lynx subdiagrams and 4 fish subdiagrams, yields both local and nonlocal UV divergent terms. The nonlocal terms are consistent with gauge symmetry and correspond to a nonlocal renormalization of the wave function. (14 refs).

  5. Identification and expression analysis of the SQUAMOSA promoter-binding protein (SBP)-box gene family in Prunus mume.

    Science.gov (United States)

    Xu, Zongda; Sun, Lidan; Zhou, Yuzhen; Yang, Weiru; Cheng, Tangren; Wang, Jia; Zhang, Qixiang

    2015-10-01

    SQUAMOSA promoter-binding protein (SBP)-box family genes encode plant-specific transcription factors that play crucial roles in plant development, especially flower and fruit development. However, little information on this gene family is available for Prunus mume, an ornamental and fruit tree widely cultivated in East Asia. To explore the evolution of SBP-box genes in Prunus and explore their functions in flower and fruit development, we performed a genome-wide analysis of the SBP-box gene family in P. mume. Fifteen SBP-box genes were identified, and 11 of them contained an miR156 target site. Phylogenetic and comprehensive bioinformatics analyses revealed that different groups of SBP-box genes have undergone different evolutionary processes and varied in their length, structure, and motif composition. Purifying selection has been the main selective constraint on both paralogous and orthologous SBP-box genes. In addition, the sequences of orthologous SBP-box genes did not diverge widely after the split of P. mume and Prunus persica. Expression analysis of P. mume SBP-box genes revealed their diverse spatiotemporal expression patterns. Three duplicated SBP-box genes may have undergone subfunctionalization in Prunus. Most of the SBP-box genes showed high transcript levels in flower buds and young fruit. The four miR156-nontargeted genes were upregulated during fruit ripening. Together, these results provide information about the evolution of SBP-box genes in Prunus. The expression analysis lays the foundation for further research on the functions of SBP-box genes in P. mume and other Prunus species, especially during flower and fruit development.

  6. IMPROVED, FAVORABLE FOR ENVIRONMENT POLYURETHANE COLD-BOX-PROCESS (COLD BOX «HUTTENES-ALBERTUS» .

    Directory of Open Access Journals (Sweden)

    A. Sergini

    2005-01-01

    Full Text Available The results of the laboratory and industrial investigations, the purpose of which is improvement of the classical Cold-box-process, i.e. the process of the slugs hardening in cold boxes, are presented.

  7. 36 CFR 1192.33 - Fare box.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Fare box. 1192.33 Section 1192.33 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD... Systems § 1192.33 Fare box. Where provided, the farebox shall be located as far forward as practicable and...

  8. Magnetorotational dynamo action in the shearing box

    Science.gov (United States)

    Walker, Justin; Boldyrev, Stanislav

    2017-09-01

    Magnetic dynamo action caused by the magnetorotational instability is studied in the shearing-box approximation with no imposed net magnetic flux. Consistent with recent studies, the dynamo action is found to be sensitive to the aspect ratio of the box: it is much easier to obtain in tall boxes (stretched in the direction normal to the disc plane) than in long boxes (stretched in the radial direction). Our direct numerical simulations indicate that the dynamo is possible in both cases, given a large enough magnetic Reynolds number. To explain the relatively larger effort required to obtain the dynamo action in a long box, we propose that the turbulent eddies caused by the instability most efficiently fold and mix the magnetic field lines in the radial direction. As a result, in the long box the scale of the generated strong azimuthal (stream-wise directed) magnetic field is always comparable to the scale of the turbulent eddies. In contrast, in the tall box the azimuthal magnetic flux spreads in the vertical direction over a distance exceeding the scale of the turbulent eddies. As a result, different vertical sections of the tall box are permeated by large-scale non-zero azimuthal magnetic fluxes, facilitating the instability. In agreement with this picture, the cases when the dynamo is efficient are characterized by a strong intermittency of the local azimuthal magnetic fluxes.

  9. Unification of box shapes in molecular simulations

    NARCIS (Netherlands)

    Bekker, H.

    1997-01-01

    In molecular simulations with periodic boundary conditions the computational box may have five different shapes: triclinic; the hexagonal prism; two types of dodecahedrons; and the truncated octahedron. In this article, we show that every molecular simulation, formulated in one of these boxes, can

  10. An effective box trap for capturing lynx

    Science.gov (United States)

    Jay A. Kolbe; John R. Squires; Thomas W. Parker

    2003-01-01

    We designed a box trap for capturing lynx (Lynx lynx) that is lightweight, safe, effective, and less expensive than many commercial models. It can be constructed in approximately 3-4 hours from readily available materials. We used this trap to capture 40 lynx 89 times (96% of lynx entering traps) and observed no trapping related injuries. We compare our box...

  11. Modern biotechnology Panacea or new Pandora's box?

    NARCIS (Netherlands)

    Tramper, J.; Yang Zhu, Yang

    2011-01-01

    According to Greek mythology Pandora was sent down to earth upon the orders of Zeus. She was given a mysterious box which she was not allowed to open. However, Pandora was very curious and when she arrived on earth she couldn?t help taking a peek inside the box. She saw that it was filled with gifts

  12. Cosmetic Foot Surgery: Fashion's Pandora's Box

    Science.gov (United States)

    ... Fashion’s Pandora’s Box? A A A | Print | Share Cosmetic Foot Surgery: Fashion’s Pandora’s Box? Foot and ankle ... extreme and imprudent as it may sound, the cosmetic surgery craze is not just for faces anymore— ...

  13. Box Plots in the Australian Curriculum

    Science.gov (United States)

    Watson, Jane M.

    2012-01-01

    This article compares the definition of "box plot" as used in the "Australian Curriculum: Mathematics" with other definitions used in the education community; describes the difficulties students experience when dealing with box plots; and discusses the elaboration that is necessary to enable teachers to develop the knowledge…

  14. 49 CFR 38.33 - Fare box.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Fare box. 38.33 Section 38.33 Transportation Office of the Secretary of Transportation AMERICANS WITH DISABILITIES ACT (ADA) ACCESSIBILITY SPECIFICATIONS FOR TRANSPORTATION VEHICLES Buses, Vans and Systems § 38.33 Fare box. Where provided, the farebox...

  15. The G-Box Transcriptional Regulatory Code in Arabidopsis1[OPEN

    Science.gov (United States)

    Shepherd, Samuel J.K.; Brestovitsky, Anna; Dickinson, Patrick; Biswas, Surojit

    2017-01-01

    Plants have significantly more transcription factor (TF) families than animals and fungi, and plant TF families tend to contain more genes; these expansions are linked to adaptation to environmental stressors. Many TF family members bind to similar or identical sequence motifs, such as G-boxes (CACGTG), so it is difficult to predict regulatory relationships. We determined that the flanking sequences near G-boxes help determine in vitro specificity but that this is insufficient to predict the transcription pattern of genes near G-boxes. Therefore, we constructed a gene regulatory network that identifies the set of bZIPs and bHLHs that are most predictive of the expression of genes downstream of perfect G-boxes. This network accurately predicts transcriptional patterns and reconstructs known regulatory subnetworks. Finally, we present Ara-BOX-cis (araboxcis.org), a Web site that provides interactive visualizations of the G-box regulatory network, a useful resource for generating predictions for gene regulatory relations. PMID:28864470

  16. North American box turtles: A natural history

    Science.gov (United States)

    Dodd, C. Kenneth

    2002-01-01

    Once a familiar backyard visitor in many parts of the United States and Mexico, the box turtle is losing the battle against extinction. In North American Box Turtles, C. Kenneth Dodd, Jr., has written the first book-length natural history of the twelve species and subspecies of this endangered animal. This volume includes comprehensive information on the species’ evolution, behavior, courtship and reproduction, habitat use, diet, population structure, systematics, and disease. Special features include color photos of all species, subspecies, and their habitats; a simple identification guide to both living and fossil species; and a summary of information on fossil Terrapene and Native uses of box turtles. End-of-chapter sections highlight future research directions, including the need for long-term monitoring and observation of box turtles within their natural habitat and conservation applications. A glossary and a bibliography of literature on box turtles accompany the text.

  17. Thermo-mechanical Design Methodology for ITER Cryodistribution cold boxes

    Science.gov (United States)

    Shukla, Vinit; Patel, Pratik; Das, Jotirmoy; Vaghela, Hitensinh; Bhattacharya, Ritendra; Shah, Nitin; Choukekar, Ketan; Chang, Hyun-Sik; Sarkar, Biswanath

    2017-04-01

    The ITER cryo-distribution (CD) system is in charge of proper distribution of the cryogen at required mass flow rate, pressure and temperature level to the users; namely the superconducting (SC) magnets and cryopumps (CPs). The CD system is also capable to use the magnet structures as a thermal buffer in order to operate the cryo-plant as much as possible at a steady state condition. A typical CD cold box is equipped with mainly liquid helium (LHe) bath, heat exchangers (HX’s), cryogenic valves, filter, heaters, cold circulator, cold compressor and process piping. The various load combinations which are likely to occur during the life cycle of the CD cold boxes are imposed on the representative model and impacts on the system are analyzed. This study shows that break of insulation vacuum during nominal operation (NO) along with seismic event (Seismic Level-2) is the most stringent load combination having maximum stress of 224 MPa. However, NO+SMHV (Séismes Maximaux Historiquement Vraisemblables = Maximum Historically Probable Earthquakes) load combination is having the least safety margin and will lead the basis of the design of the CD system and its sub components. This paper presents and compares the results of different load combinations which are likely to occur on a typical CD cold box.

  18. Hydro-Balanced Stuffing Box field test

    Energy Technology Data Exchange (ETDEWEB)

    Giangiacomo, L.A.

    1999-05-28

    The Hydro-Balanced Stuffing Box is a seal assembly for polished rod pumping installations commonly used in oil and gas pumping well installations to contain produced well fluids. The improved stuffing box was developed and patented by Harold H. Palmour of The Palmour Group of Livingston, TX. The stuffing box is designed to reduce the incidence of seal leakage and to utilize an environmentally safe fluid, so that if there is any leakage, environmental damage is reduced or eliminated. The unit was tested on two wells at the Rocky Mountain Oilfield Testing Center. During the test period, the performance of the stuffing box was measured by monitoring the pressure on the tubing and the inner chamber with a Barton Two-pen recorder. The amount of safe fluid consumed, fluid leakage at the top of the stuffing box, pressure supplied from the nitrogen bottle, ambient temperature, and polish rod temperature was recorded. The stuffing box is capable of providing a better seal between well fluids an d the environment than conventional stuffing boxes. It allows the polished rod to operate cooler and with lubrication, extending the life of the packing elements, and reducing the amount of attention required to prevent leakage.

  19. [Present views on boxing--Henner's legacy].

    Science.gov (United States)

    Tichý, J

    1997-05-29

    Fifty years ago academician Henner formulated clearly the negative view of neurologists on boxing as practised in his time. It was his merit that a protective helmet was introduced, many of his demands concerning the regime after a KO and the importance of medical examinations were no yet adequately appreciated. At the opportunity of the 100th anniversary of Henner's birth and the fiftieth anniversary of the Clinic he founded in the premises of saint Catherine the author discusses contemporary views on boxing, the risk of repeated injuries for the development of encephalopathia pugilistica and their relationship to Alzheimer's disease. Contemporary boxing is a spectacle which is a continuation of historical fights of gladiators. If the main objective is to hurt the adversary, this activity does not deserve the name of "sport" Sport should promote and maintain physical and mental health which is not the case in professional boxing.

  20. Grey Box Modelling of Hydrological Systems

    DEFF Research Database (Denmark)

    Thordarson, Fannar Ørn

    The main topic of the thesis is grey box modelling of hydrologic systems, as well as formulation and assessment of their embedded uncertainties. Grey box model is a combination of a white box model, a physically-based model that is traditionally formulated using deterministic ordinary differential...... represent a stochastic state space model. In the grey box model the total noise is divided into a measurement noise and a process noise. The process noise is due to model approximations, undiscovered input and uncertainties in the input series. Estimates of the process noise can be used to highlight...... in the model, or formulation of process noise can be considered so that it meets the physical limits of the hydrological system and give an adequate description of the embedded uncertainty in model structure. The thesis consists of two parts: a summary report and a part which contains six scientific papers...

  1. Black-Box Search by Unbiased Variation

    DEFF Research Database (Denmark)

    Lehre, Per Kristian; Witt, Carsten

    2012-01-01

    The complexity theory for black-box algorithms, introduced by Droste, Jansen, and Wegener (Theory Comput. Syst. 39:525–544, 2006), describes common limits on the efficiency of a broad class of randomised search heuristics. There is an obvious trade-off between the generality of the black-box model...... and the strength of the bounds that can be proven in such a model. In particular, the original black-box model provides for well-known benchmark problems relatively small lower bounds, which seem unrealistic in certain cases and are typically not met by popular search heuristics.In this paper, we introduce a more...... restricted black-box model for optimisation of pseudo-Boolean functions which we claim captures the working principles of many randomised search heuristics including simulated annealing, evolutionary algorithms, randomised local search, and others. The key concept worked out is an unbiased variation operator...

  2. EPA EcoBox Tools by Stressors

    Science.gov (United States)

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  3. Packing a cake into a box

    KAUST Repository

    Skopenkov, Mikhail

    2011-05-01

    Given a triangular cake and a box in the shape of its mirror image, how can the cake be cut into a minimal number of pieces so that it can be put into the box? The cake has icing, so we are not allowed to put it into the box upside down. V. G. Boltyansky asked this question in 1977 and showed that three pieces always suffice. In this paper we provide examples of cakes that cannot be cut into two pieces to be put into the box. This shows that three is the answer to Boltyansky\\'s question. We also give examples of cakes which can be cut into two pieces. © THE MATHEMATICAL ASSOCIATION OF AMERICA.

  4. ENERGY STAR Certified Set Top Boxes

    Data.gov (United States)

    U.S. Environmental Protection Agency — Certified models meet all ENERGY STAR requirements as listed in the Version 5.1 ENERGY STAR Program Requirements for Set-top Boxes that are effective as of January...

  5. A Lithium Vapor Box Divertor Similarity Experiment

    Science.gov (United States)

    Cohen, Robert A.; Emdee, Eric D.; Goldston, Robert J.; Jaworski, Michael A.; Schwartz, Jacob A.

    2017-10-01

    A lithium vapor box divertor offers an alternate means of managing the extreme power density of divertor plasmas by leveraging gaseous lithium to volumetrically extract power. The vapor box divertor is a baffled slot with liquid lithium coated walls held at temperatures which increase toward the divertor floor. The resulting vapor pressure differential drives gaseous lithium from hotter chambers into cooler ones, where the lithium condenses and returns. A similarity experiment was devised to investigate the advantages offered by a vapor box divertor design. We discuss the design, construction, and early findings of the vapor box divertor experiment including vapor can construction, power transfer calculations, joint integrity tests, and thermocouple data logging. Heat redistribution of an incident plasma-based heat flux from a typical linear plasma device is also presented. This work supported by DOE Contract No. DE-AC02-09CH11466 and The Princeton Environmental Institute.

  6. Random Young diagrams in a Rectangular Box

    DEFF Research Database (Denmark)

    Beltoft, Dan; Boutillier, Cédric; Enriquez, Nathanaël

    We exhibit the limit shape of random Young diagrams having a distribution proportional to the exponential of their area, and confined in a rectangular box. The Ornstein-Uhlenbeck bridge arises from the fluctuations around the limit shape.......We exhibit the limit shape of random Young diagrams having a distribution proportional to the exponential of their area, and confined in a rectangular box. The Ornstein-Uhlenbeck bridge arises from the fluctuations around the limit shape....

  7. Tracking the Motion of Box Jellyfish

    OpenAIRE

    Kjellberg, Tobias; Palmér, Tobias; Oskarsson, Magnus; Åström, Karl

    2014-01-01

    In this paper we investigate a system for tracking the motion of box jellyfish tripedalia cystophora in a special test setup. The goal is to measure the motor response of the animal given certain visual stimuli. The approach is based on tracking the special sensory structures – the rhopalia – of the box jellyfish from high-speed video sequences. We have focused on a realtime system with simple building blocks in our system. However, using a combination of simple intensity...

  8. Box Lesion with Single Radiofrequency Clamp.

    Science.gov (United States)

    Shaikhrezai, Kasra; Spadaccio, Cristiano; Hunter, Steven

    2017-04-12

    We introduce a maneuver to perform the box lesion as a part of Cox maze IV procedure with single radiofrequency clamp. The maneuver entails engaging the right pulmonary veins with the clamp, then advancing the clamp jaws underneath the superior vena cava through the transverse sinus to include the roof and the left pulmonary veins in the clamp. We regularly use this technique for box lesion with desirable transmurality. Georg Thieme Verlag KG Stuttgart · New York.

  9. Autoantibodies to box A of high mobility group box 1 in systemic lupus erythematosus.

    Science.gov (United States)

    Schaper, F; de Leeuw, K; Horst, G; Maas, F; Bootsma, H; Heeringa, P; Limburg, P C; Westra, J

    2017-06-01

    Autoantibodies to nuclear structures are a hallmark of systemic lupus erythematosus (SLE), including autoantibodies to nuclear protein high mobility group box 1 (HMGB1). HMGB1 consists of three separate domains: box A, box B and an acidic tail. Recombinant box A acts as a competitive antagonist for HMGB1 and might be an interesting treatment option in SLE. However, antibodies to box A might interfere. Therefore, levels of anti-box A were examined in SLE patients in association with disease activity and clinical parameters. Serum anti-box A was measured in 86 SLE patients and 44 age- and sex-matched healthy controls (HC). Serum samples of 28 patients with primary Sjögren's syndrome and 32 patients with rheumatoid arthritis were included as disease controls. Anti-HMGB1 and anti-box B levels were also measured by enzyme-linked immunosorbent assay during quiescent disease [SLE Disease Activity Index (SLEDAI) ≤ 4, n = 47] and active disease (SLEDAI ≥ 5, n = 39). Anti-box A levels in active SLE patients were higher compared to quiescent patients, and were increased significantly compared to HC and disease controls. Anti-box A levels correlated positively with SLEDAI and anti-dsDNA levels and negatively with complement C3 levels. Increased levels of anti-box A antibodies were present in the majority of patients with nephritic (73%) and non-nephritic exacerbations (71%). Antibodies to the box A domain of HMGB1 might be an interesting new biomarker, as these had a high specificity for SLE and were associated with disease activity. Longitudinal studies should be performed to evaluate whether these antibodies perform better in predicting an exacerbation, especially non-nephritic exacerbations. © 2017 British Society for Immunology.

  10. HYDROGEN AND VOC RETENTION IN WASTE BOXES

    Energy Technology Data Exchange (ETDEWEB)

    PACE ME; MARUSICH RM

    2008-11-21

    The Hanford Waste Management Project Master Documented Safety Analysis (MDSA) (HNF-14741, 2003) identifies derived safety controls to prevent or mitigate the risks of a single-container deflagration during operations requiring moving, venting or opening transuranic (TRU)-waste containers. The issue is whether these safety controls are necessary for operations involving TRU-waste boxes that are being retrieved from burial at the Hanford Site. This paper investigates the potential for a deflagration hazard within these boxes and whether safety controls identified for drum deflagration hazards should be applied to operations involving these boxes. The study evaluates the accumulation of hydrogen and VOCs within the waste box and the transport of these gases and vapors out of the waste box. To perform the analysis, there were numerous and major assumptions made regarding the generation rate and the transport pathway dimensions and their number. Since there is little actual data with regards to these assumptions, analyses of three potential configurations were performed to obtain some indication of the bounds of the issue (the concentration of hydrogen or flammable VOCs within a waste box). A brief description of each of the three cases along with the results of the analysis is summarized.

  11. Box-Cox transformation for QTL mapping.

    Science.gov (United States)

    Yang, Runqing; Yi, Nengjun; Xu, Shizhong

    2006-01-01

    The maximum likelihood method of QTL mapping assumes that the phenotypic values of a quantitative trait follow a normal distribution. If the assumption is violated, some forms of transformation should be taken to make the assumption approximately true. The Box-Cox transformation is a general transformation method which can be applied to many different types of data. The flexibility of the Box-Cox transformation is due to a variable, called transformation factor, appearing in the Box-Cox formula. We developed a maximum likelihood method that treats the transformation factor as an unknown parameter, which is estimated from the data simultaneously along with the QTL parameters. The method makes an objective choice of data transformation and thus can be applied to QTL analysis for many different types of data. Simulation studies show that (1) Box-Cox transformation can substantially increase the power of QTL detection; (2) Box-Cox transformation can replace some specialized transformation methods that are commonly used in QTL mapping; and (3) applying the Box-Cox transformation to data already normally distributed does not harm the result.

  12. MYC2 differentially regulates GATA-box containing promoters during seedling development in Arabidopsis.

    Science.gov (United States)

    Gangappa, Sreeramaiah N; Chattopadhyay, Sudip

    2013-10-01

    MY C2 is an important transcription factor, which modulates transcription by directly binding to Z-, G- and E-box elements present in the promoters of light and different stress responsive genes. Very recently, we have shown that MY C2 plays a role in the regulation of Z- and/or G-box containing promoters during both seedling and adult plant growth. Although, MY C2 does not bind to the GATA box light responsive element (LRE ) in vitro as shown in DNA binding assays, its involvement in the regulation of GATA -box containing promoter in planta, if any, is not known. Here, we report that the promoter activity of GATA-NOS101 in atmyc2 mutant was found to be similar to wild-type in BL and dark grown seedlings, whereas it was found to be lower compared with wild-type as revealed from GUS staining results. Further, we will discuss the consequences of MY C2 regulating GATA -box containing promoter in combination with G-box containing promoters.

  13. Divergence of Recently Duplicated Mg-Type MADS-Box Genes in Petunia

    NARCIS (Netherlands)

    Bemer, M.; Gordon, J.; Weterings, K.; Angenent, G.C.

    2010-01-01

    The MADS-box transcription factor family has expanded considerably in plants via gene and genome duplications and can be subdivided into type I and MIKC-type genes. The two gene classes show a different evolutionary history. Whereas the MIKC-type genes originated during ancient genome duplications,

  14. Factors affecting microcuttings of Stevia using a mist-chamber propagation box.

    Science.gov (United States)

    Osman, Mohamad; Samsudin, Nur Syamimi; Faruq, Golam; Nezhadahmadi, Arash

    2013-01-01

    Stevia rebaudiana Bertoni is a member of Compositae family. Stevia plant has zero calorie content and its leaves are estimated to be 300 times sweeter than sugar. This plant is believed to be the most ideal substitute for sugar and important to assist in medicinal value especially for diabetic patients. In this study, microcutting techniques using a mist-chamber propagation box were used as it was beneficial for propagation of Stevia and gave genetic uniformity to the plant. The effects of different treatments on root stimulation of Stevia in microcuttings technique were evaluated. Treatments studied were different sizes of shoot cuttings, plant growth regulators, lights, and shades. Data logger was used to record the mean value of humidity (>90% RH), light intensity (673-2045 lx), and temperature (28.6-30.1°C) inside the mist-chamber propagation box. From analysis of variance, there were significant differences between varieties and treatments in parameters studied (P Stevia.

  15. Genomic identification, characterization and differential expression analysis of SBP-box gene family in Brassica napus.

    Science.gov (United States)

    Cheng, Hongtao; Hao, Mengyu; Wang, Wenxiang; Mei, Desheng; Tong, Chaobo; Wang, Hui; Liu, Jia; Fu, Li; Hu, Qiong

    2016-09-08

    SBP-box genes belong to one of the largest families of transcription factors. Though members of this family have been characterized to be important regulators of diverse biological processes, information of SBP-box genes in the third most important oilseed crop Brassica napus is largely undefined. In the present study, by whole genome bioinformatics analysis and transcriptional profiling, 58 putative members of SBP-box gene family in oilseed rape (Brassica napus L.) were identified and their expression pattern in different tissues as well as possible interaction with miRNAs were analyzed. In addition, B. napus lines with contrasting branch angle were used for investigating the involvement of SBP-box genes in plant architecture regulation. Detailed gene information, including genomic organization, structural feature, conserved domain and phylogenetic relationship of the genes were systematically characterized. By phylogenetic analysis, BnaSBP proteins were classified into eight distinct groups representing the clear orthologous relationships to their family members in Arabidopsis and rice. Expression analysis in twelve tissues including vegetative and reproductive organs showed different expression patterns among the SBP-box genes and a number of the genes exhibit tissue specific expression, indicating their diverse functions involved in the developmental process. Forty-four SBP-box genes were ascertained to contain the putative miR156 binding site, with 30 and 14 of the genes targeted by miR156 at the coding and 3'UTR region, respectively. Relative expression level of miR156 is varied across tissues. Different expression pattern of some BnaSBP genes and the negative correlation of transcription levels between miR156 and its target BnaSBP gene were observed in lines with different branch angle. Taken together, this study represents the first systematic analysis of the SBP-box gene family in Brassica napus. The data presented here provides base foundation for

  16. The U-box family genes in Medicago truncatula: Key elements in response to salt, cold, and drought stresses.

    Science.gov (United States)

    Song, Jianbo; Mo, Xiaowei; Yang, Haiqi; Yue, Luming; Song, Jun; Mo, Beixin

    2017-01-01

    The ubiquitination pathway regulates growth, development, and stress responses in plants, and the U-box protein family of ubiquitin ligases has important roles in this pathway. Here, 64 putative U-box proteins were identified in the Medicago truncatula genome. In addition to the conserved U-box motif, other functional domains, such as the ARM, kinase, KAP, and WD40 domains, were also detected. Phylogenetic analysis of the M. truncatula U-box proteins grouped them into six subfamilies, and chromosomal mapping and synteny analyses indicated that tandem and segmental duplications may have contributed to the expansion and evolution of the U-box gene family in this species. Using RNA-seq data from M. truncatula seedlings subjected to three different abiotic stresses, we identified 33 stress-inducible plant U-box genes (MtPUBs). Specifically, 25 salinity-, 15 drought-, and 16 cold-regulated MtPUBs were detected. Among them, MtPUB10, MtPUB17, MtPUB18, MtPUB35, MtPUB42, and MtPUB44 responded to all three stress conditions. Expression profiling by qRT-PCR was consistent with the RNA-seq data, and stress-related elements were identified in the promoter regions. The present findings strongly indicate that U-box proteins play critical roles in abiotic stress response in M. truncatula.

  17. Complementarity in the Einstein-Bohr photon box

    NARCIS (Netherlands)

    Dieks, D.G.B.J.; Lam, S

    2008-01-01

    The Bohr-Einstein photon box thought experiment is a forerunner of the EPR experiment: a packet of radiation escapes from a box, and the box-plus-radiation state remains entangled. Hence, a measurement on the box makes a difference for the state of the far-away radiation long after its escape. This

  18. Changes in position and quality of preferred nest box: effects on nest box use by laying hens

    DEFF Research Database (Denmark)

    Riber, Anja Brinch; Nielsen, Birte L.

    2013-01-01

    hens were housed in pens, each with five identical nest boxes in different positions: Two single (in a corner or not) and a triplet of nest boxes (one of which in a corner). The use of nest boxes was determined by the number of eggs laid daily in each box. Three experiments, each lasting 10 days, were...

  19. A Grey-Box Model for Spray Drying Plants

    DEFF Research Database (Denmark)

    Petersen, Lars Norbert; Poulsen, Niels Kjølstad; Niemann, Hans Henrik

    2013-01-01

    Multi-stage spray drying is an important and widely used unit operation in the production of food powders. In this paper we develop and present a dynamic model of the complete drying process in a multi-stage spray dryer. The dryer is divided into three stages: The spray stage and two fluid bed...

  20. Advances in the theory of box integrals

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, J.M.; Crandall, R.E.

    2009-06-25

    Box integrals - expectations <|{rvec r}|{sup s}> or <|{rvec r}-{rvec q}|{sup s}> over the unit n-cube (or n-box) - have over three decades been occasionally given closed forms for isolated n,s. By employing experimental mathematics together with a new, global analytic strategy, we prove that for n {le} 4 dimensions the box integrals are for any integer s hypergeometrically closed in a sense we clarify herein. For n = 5 dimensions, we show that a single unresolved integral we call K{sub 5} stands in the way of such hyperclosure proofs. We supply a compendium of exemplary closed forms that naturally arise algorithmically from this theory.

  1. Reassessment of the nonlocality of correlation boxes

    Energy Technology Data Exchange (ETDEWEB)

    Costa, A.P.; Parisio, Fernando, E-mail: parisio@df.ufpe.br

    2017-01-15

    Correlation boxes are hypothetical systems usually designed to produce the maximal algebraic violation of a Bell inequality, beyond the quantum bound and without superluminal signalling. The fact that these systems show stronger correlations than those presented by maximally entangled quantum states, as the spin singlet, has been regarded as a demonstration that the former are more nonlocal than the latter. By applying an alternative, consistent measure of nonlocality to a family of correlation boxes, we show that this conclusion is not necessarily true. Complementarily, we define a class of systems displaying subquantum correlations which, nevertheless, are more nonlocal than the singlet state, showing that the extent of the numeric violation of an inequality may have little to do with the degree of nonlocality, especially in the case of correlation boxes.

  2. A white box perspective on behavioural adaptation

    DEFF Research Database (Denmark)

    Bruni, Roberto; Corradini, Andrea; Gadducci, Fabio

    2015-01-01

    We present a white-box conceptual framework for adaptation developed in the context of the EU Project ASCENS coordinated by Martin Wirsing. We called it CoDA, for Control Data Adaptation, since it is based on the notion of control data. CoDA promotes a neat separation between application and adap......We present a white-box conceptual framework for adaptation developed in the context of the EU Project ASCENS coordinated by Martin Wirsing. We called it CoDA, for Control Data Adaptation, since it is based on the notion of control data. CoDA promotes a neat separation between application...

  3. Virtualisointi VirtualBox-ohjelman avulla

    OpenAIRE

    Pakka, Markku

    2011-01-01

    Tutkielmassani käsittelen aluksi palvelimia ja niiden tietoturvaa yleisesti, koska palvelinten tietoturva on tärkeää virtualisoitujen käyttöjärjestelmien turvallisuuden ja toimivuuden kannalta. Sen jälkeen siirryn käsittelemään virtualisointia ja sen tulevaisuutta. Seuraavaksi tutkin VirtualBox-ohjelmaa. Aluksi asennan VirtualBox-ohjelman Windows Vista-koneelle. Sen jälkeen käsittelen VirtualBoxin käyttöliittymää ja asennan Ubuntun virtuaalikäyttöjärjestelmäksi VirtualBoxin avulla. ...

  4. CASAS: A Smart Home in a Box.

    Science.gov (United States)

    Cook, Diane J; Crandall, Aaron S; Thomas, Brian L; Krishnan, Narayanan C

    2013-07-01

    While the potential benefits of smart home technology are widely recognized, a lightweight design is needed for the benefits to be realized at a large scale. We introduce the CASAS "smart home in a box", a lightweight smart home design that is easy to install and provides smart home capabilities out of the box with no customization or training. We discuss types of data analysis that have been performed by the CASAS group and can be pursued in the future by using this approach to designing and implementing smart home technologies.

  5. Plant planting

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes planting activities on Neal Smith National Wildlife Refuge (formerly Walnut Creek National Wildlife Refuge) between 1995 and 2009.

  6. Genome-Wide Analyses of the Soybean F-Box Gene Family in Response to Salt Stress.

    Science.gov (United States)

    Jia, Qi; Xiao, Zhi-Xia; Wong, Fuk-Ling; Sun, Song; Liang, Kang-Jing; Lam, Hon-Ming

    2017-04-12

    The F-box family is one of the largest gene families in plants that regulate diverse life processes, including salt responses. However, the knowledge of the soybean F-box genes and their roles in salt tolerance remains limited. Here, we conducted a genome-wide survey of the soybean F-box family, and their expression analysis in response to salinity via in silico analysis of online RNA-sequencing (RNA-seq) data and quantitative reverse-transcription polymerase chain reaction (qRT-PCR) to predict their potential functions. A total of 725 potential F-box proteins encoded by 509 genes were identified and classified into 9 subfamilies. The gene structures, conserved domains and chromosomal distributions were characterized. There are 76 pairs of duplicate genes identified, including genome-wide segmental and tandem duplication events, which lead to the expansion of the number of F-box genes. The in silico expression analysis showed that these genes would be involved in diverse developmental functions and play an important role in salt response. Our qRT-PCR analysis confirmed 12 salt-responding F-box genes. Overall, our results provide useful information on soybean F-box genes, especially their potential roles in salt tolerance.

  7. Study of WATCH GRB error boxes

    DEFF Research Database (Denmark)

    Gorosabel, J.; Castro-Tirado, A. J.; Lund, Niels

    1995-01-01

    We have studied the first WATCH GRB Catalogue ofγ-ray Bursts in order to find correlations between WATCH GRB error boxes and a great variety of celestial objects present in 33 different catalogues. No particular class of objects has been found to be significantly correlated with the WATCH GRBs....

  8. Expo-Box: Submit Tool Information

    Science.gov (United States)

    EPA-Expo-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases, mode

  9. Nest Boxes Artificial Homes for Woodland Mammals.

    Science.gov (United States)

    Decker, Daniel J.; Kelley, John W.

    1983-01-01

    Provides instructions for constructing artificial "homes" for squirrels, raccoons, and rabbits. These include squirrel dens constructed from discarded automobile tires and squirrel nest boxes, raccoon dens, and rabbit burrows constructed from wood. Includes a chart giving dimensions of materials needed and suggestions on where to place the…

  10. Cereal Box Design: An Interdisciplinary Graphics Activity

    Science.gov (United States)

    Fitzgerald, Mike; Tsosie, Teri

    2012-01-01

    The cereal box design activity is intriguing both for its simplicity and the resourcefulness that it can generate in young people. Also, it lends itself to a variety of curriculums. It covers both consumerism and Design for the Environment (DfE) concepts broadly and in depth. The activity introduces a wide range of topics. They include graphic…

  11. Comparing Box Plot Distributions: A Teacher's Reasoning

    Science.gov (United States)

    Pfannkuch, Maxine

    2006-01-01

    Drawing conclusions from the comparison of datasets using informal statistical inference is a challenging task since the nature and type of reasoning expected is not fully understood. In this paper a secondary teacher's reasoning from the comparison of box plot distributions during the teaching of a Year 11 (15-year-old) class is analyzed. From…

  12. Activities: Exploring Data with Box Plots.

    Science.gov (United States)

    Bryan, Elizabeth H.

    1988-01-01

    This set of activity sheets requires students to organize and display data with a box-and-whiskers graph. Students use the plot as a summary display to detect patterns and to highlight the important features of the data for purposes of comparison. (PK)

  13. Choreographies with Secure Boxes and Compromised Principals

    DEFF Research Database (Denmark)

    Carbone, Marco; Guttman, Joshua

    2009-01-01

      We equip choreography-level session descriptions with a simple abstraction of a security infrastruc- ture. Message components may be enclosed within (possibly nested) ”boxes” annotated with the intended source and destination of those components. The boxes are to be implemented with cryp...

  14. One-dimensional oscillator in a box

    Energy Technology Data Exchange (ETDEWEB)

    Amore, Paolo [Facultad de Ciencias, Universidad de Colima, Bernal DIaz del Castillo 340, Colima, Colima (Mexico); Fernandez, Francisco M [INIFTA (UNLP, CCT La Plata-CONICET), Division Quimica Teorica, Blvd 113 S/N, Sucursal 4, Casilla de Correo 16, 1900 La Plata (Argentina)], E-mail: paolo@ucol.mx, E-mail: fernande@quimica.unlp.edu.ar

    2010-01-15

    We discuss a quantum-mechanical model of two particles that interact by means of a harmonic potential and are confined to a one-dimensional box with impenetrable walls. We apply perturbation theory to the cases of different and equal masses and analyse the symmetry of the states in the latter case. We compare the approximate perturbation results with accurate numerical ones.

  15. The black box of a mysterious disorder

    NARCIS (Netherlands)

    Van der Helm, F.; Schouten, A.; De Vlugt, E.; Van der Sanden, M.

    2005-01-01

    Red and swollen limbs that feel hot or cold, a numb feeling, lack of mobility, and worst of all, pain. These are symptoms of post-traumatic dystrophy (PD). Researchers from various disciplines are working together in the TREND research consortium to open the black box of this mysterious disorder.

  16. Minimal Solutions to the Box Problem

    Science.gov (United States)

    Chuang, Jer-Chin

    2009-01-01

    The "box problem" from introductory calculus seeks to maximize the volume of a tray formed by folding a strictly rectangular sheet from which identical squares have been cut from each corner. In posing such questions, one would like to choose integral side-lengths for the sheet so that the excised squares have rational or integral side-length.…

  17. Reflective Cracking between Precast Prestressed Box Girders

    Science.gov (United States)

    2017-06-30

    The adjacent precast prestressed concrete box-beam bridge is the bridge of choice for short and short-to-medium span bridges. This choice is because of the ease of construction, favorable span-to-depth ratios, aesthetic appeal, and high torsional sti...

  18. The clinicopathological significance of forkhead box P1 and forkhead box O3a in pancreatic ductal adenocarcinomas.

    Science.gov (United States)

    Luo, Xin; Yang, Zhulin; Liu, Xiao; Liu, Ziru; Miao, Xiongying; Li, Daiqiang; Zou, Qiong; Yuan, Yuan

    2017-05-01

    Pancreatic ductal adenocarcinoma is a highly malignant tumor with poor prognosis, and the biomarkers for the early diagnosis, targeting therapy, and prognosis are still not clinically available. This study investigated the expression of forkhead box P1 and forkhead box O3a proteins in human pancreatic ductal adenocarcinoma tumor tissues and pancreatic tissues with and without benign lesions using immunohistochemical staining. Results showed that the positive rates of forkhead box P1 and forkhead box O3a protein expression were significantly lower in pancreatic ductal adenocarcinoma tumors compared to peritumoral tissues, benign pancreatic tissues, and normal pancreatic tissues (p box P1 and forkhead box O3a protein expression exhibited dysplasia or intraepithelial neoplasia. The positive rates of forkhead box P1 and forkhead box O3a expression were significantly lower in cases with tumor mass >5 cm, lymph node metastasis, invasion to surrounding tissues and organs, and tumor-node-metastasis III + IV stage disease compared to cases with tumor mass ⩽5 cm (p box P1 and forkhead box O3a expression survived significantly shorter than patients with positive forkhead box P1 and forkhead box O3a expression (p = 0.000). Cox multivariate analysis revealed that negative forkhead box P1 and forkhead box O3a expression was an independent poor prognosis factor in pancreatic ductal adenocarcinoma patients. The area under the curve of a receiver operating characteristic curve was 0.642 for forkhead box P1 (95% confidence interval: 0.553-0.730) and 0.655 for forkhead box O3a (95% confidence interval: 0.6568-0.742). Loss of forkhead box P1 and forkhead box O3a protein expression is associated with carcinogenesis, progression, and poor prognosis in patients with pancreatic ductal adenocarcinomas.

  19. Can the design of glove dispensing boxes influence glove contamination?

    Science.gov (United States)

    Assadian, O; Leaper, D J; Kramer, A; Ousey, K J

    2016-11-01

    Few studies have explored the microbial contamination of glove boxes in clinical settings. The objective of this observational study was to investigate whether a new glove packaging system in which single gloves are dispensed vertically, cuff end first, has lower levels of contamination on the gloves and on the surface around the box aperture compared with conventional glove boxes. Seven participating sites were provided with vertical glove dispensing systems (modified boxes) and conventional boxes. Before opening glove boxes, the surface around the aperture was sampled microbiologically to establish baseline levels of superficial contamination. Once the glove boxes were opened, the first pair of gloves in each box was sampled for viable bacteria. Thereafter, testing sites were visited on a weekly basis over a period of six weeks and the same microbiological assessments were made. The surface near the aperture of the modified boxes became significantly less contaminated over time compared with the conventional boxes (Pcontamination around the aperture. Overall, gloves from modified boxes showed significantly less colony-forming unit contamination than gloves from conventional boxes (Pcontamination. This simple improvement to glove box design reduces contamination of unused gloves. Such modifications could decrease the risk of microbial cross-transmission in settings that use gloves. However, such advantages do not substitute for strict hand hygiene compliance and appropriate use of non-sterile, single-use gloves. Copyright © 2016 The Healthcare Infection Society. All rights reserved.

  20. Biochemical function of typical and variant Arabidopsis thaliana U-box E3 ubiquitin-protein ligases

    DEFF Research Database (Denmark)

    Wiborg, Jakob; O'Shea, Charlotte; Skriver, Karen

    2008-01-01

    respectively, but no productive interaction was observed with the UBC15 E2 tested. The activity of AtPUB54 [Arabidopsis thaliana (thale cress) plant U-box 54 protein] was dependent on Trp(266) in the E2-binding cleft, and the E2 selectivity was changed by substitution of this position. The function...... of the distant U-box protein, AtPUB49, representing a large family of eukaryotic proteins containing a U-box linked to a cyclophilin-like peptidyl-prolyl cis-trans isomerase domain, was characterized biochemically. AtPUB49 functioned both as a prolyl isomerase and a chaperone by catalysing cis.......g. co-existence or interactions with additional domains. The biochemical functions of AtPUB49 suggest that the protein can be involved in folding or degradation of protein substrates. Similar functions can also be retained within a protein complex with separate chaperone and U-box proteins....

  1. Elasticity of cores manufactured in cold box technology

    Directory of Open Access Journals (Sweden)

    Dobosz St. M.

    2017-03-01

    Full Text Available In the foundry industry, as in many other fields we seek to achieve the best quality with the least losses and the lowest cost. To meet these demands numerous plants increased automatization of their manufacturing processes. However, with changes in the production process it is necessary to change also the materials used. Not only casting alloys that are used in production, but also applied moulding and core sands are important. Proper selection and evaluation of the properties of used moulding mixtures is crucial in order to achieve a highly efficient production. In this article a new issue concerning the use of flexibility in foundry molding and core was mentioned. It explains the principles of measurement and interpretation of the obtained results for the cold-box moulding sands.

  2. HMG-box sequences from microbats homologous to the human SOX30 HMG-box.

    Science.gov (United States)

    Bullejos, M; Díaz de la Guardia, R; Barragán, M J; Sánchez, A

    2000-01-01

    SOX genes are a family of genes that encode for proteins which are characterised by the presence of a HMG-domain related to that of the mammalian sex-determining gene (SRY). By definition, the DNA binding domain of SOX genes is at least 50% identical to the 79 amino acid HMG domain of the SRY gene. We report here two HMG-box sequences from two microbat species (R. ferrumequinum and P. Pipistrellus) which were PCR amplified using a primer pair specific to the mouse Sry HMG-box. The high percentage of identity of this sequences with the human and mouse SOX30 HMG-box suggests that they are the SOX30 HMG-box for these two bat species.

  3. Reconciling White-Box and Black-Box Perspectives on Behavioral Self-adaptation

    OpenAIRE

    Bruni, Roberto; Corradini, Andrea; Gadducci, Fabio; Hölzl, Matthias; Lluch Lafuente, Alberto; Vandin, Andrea; Wirsing, Martin

    2015-01-01

    This paper proposes to reconcile two perspectives on behavioral adaptation commonly taken at different stages of the engineering of autonomic computing systems. Requirements engineering activities often take a black-box perspective: A system is considered to be adaptive with respect to an environment whenever the system is able to satisfy its goals irrespectively of the environment perturbations. Modeling and programming engineering activities often take a white-box perspective: A system is e...

  4. SOME MEDICINAL PLANTS USED IN

    African Journals Online (AJOL)

    VHADA

    knowledge of traditional healers on commonly used medicinal plants in Jimma. METHODS: An ethnobotanical survey was ... plants used for treatment of common diseases. The study was conducted during 20. January to 30 ... Department of Biology, Faculty of Education, Jimma University, P.O. Box 378, Jimma, Ethiopia.

  5. Structural and functional annotation of the MADS-box transcription factor family in grapevine.

    Science.gov (United States)

    Grimplet, Jérôme; Martínez-Zapater, José Miguel; Carmona, María José

    2016-01-27

    MADS-box genes encode transcription factors that are involved in developmental control and signal transduction in eukaryotes. In plants, they are associated to numerous development processes most notably those related to reproductive development: flowering induction, specification of inflorescence and flower meristems, establishment of flower organ identity, as well as regulation of fruit, seed and embryo development. Genomic analyses of MADS-box genes in different plant species are providing new relevant information on the function and evolution of this transcriptional factor family. We have performed a true genome-wide analysis of the complete set of MADS-box genes in grapevine (Vitis vinifera), analyzed their expression pattern and establish their phylogenetic relationships (including MIKC* and type I MADS-box) with genes from 16 other plant species. This study was integrated to previous works on the family in grapevine. A total of 90 MADS-box genes were detected in the grapevine reference genome by completing current gene annotations with a genome-wide analysis based on sequence similarity. We performed a thorough in-depth curation of all gene models and combined the results with gene expression information including RNAseq data to clarifying the expression of newly identified genes and improve their functional characterization. Curated data were uploaded to the ORCAE database for grapevine in the frame of the grapevine genome curation effort. This approach resulted in the identification of 30 additional MADS box genes. Among them, ten new MIKC(C) genes were identified, including a potential new group of short proteins similar to the SVP protein subfamily. The MIKC* subgroup contains six genes in grapevine that can be grouped in the S (4 genes) and P (2 genes) clades, showing less redundancy than that observed in Arabidopsis thaliana. Expression pattern of these genes in grapevine is compatible with a role in male gametophyte development. Most of the identified

  6. Experts’ Misinterpretation of Box Plots – a Dual Processing Approach

    National Research Council Canada - National Science Library

    Stephanie Lem; Patrick Onghena; Lieven Verschaffel; Wim Van Dooren

    2014-01-01

    Recent studies have shown that students often misinterpret the area of the box in box plots as representing the frequency or proportion of observations in that interval, while it actually represents density...

  7. Genome-wide identification and analysis of the MADS-box gene family in bread wheat (Triticum aestivum L.).

    Science.gov (United States)

    Ma, Jian; Yang, Yujie; Luo, Wei; Yang, Congcong; Ding, Puyang; Liu, Yaxi; Qiao, Linyi; Chang, Zhijian; Geng, Hongwei; Wang, Penghao; Jiang, Qiantao; Wang, Jirui; Chen, Guoyue; Wei, Yuming; Zheng, Youliang; Lan, Xiujin

    2017-01-01

    The MADS-box genes encode transcription factors with key roles in plant growth and development. A comprehensive analysis of the MADS-box gene family in bread wheat (Triticum aestivum) has not yet been conducted, and our understanding of their roles in stress is rather limited. Here, we report the identification and characterization of the MADS-box gene family in wheat. A total of 180 MADS-box genes classified as 32 Mα, 5 Mγ, 5 Mδ, and 138 MIKC types were identified. Evolutionary analysis of the orthologs among T. urartu, Aegilops tauschii and wheat as well as homeologous sequences analysis among the three sub-genomes in wheat revealed that gene loss and chromosomal rearrangements occurred during and/or after the origin of bread wheat. Forty wheat MADS-box genes that were expressed throughout the investigated tissues and development stages were identified. The genes that were regulated in response to both abiotic stresses (i.e., phosphorus deficiency, drought, heat, and combined drought and heat) and biotic stresses (i.e., Fusarium graminearum, Septoria tritici, stripe rust and powdery mildew) were detected as well. A few notable MADS-box genes were specifically expressed in a single tissue and those showed relatively higher expression differences between the stress and control treatment. The expression patterns of considerable MADS-box genes differed from those of their orthologs in Brachypodium, rice, and Arabidopsis. Collectively, the present study provides new insights into the possible roles of MADS-box genes in response to stresses and will be valuable for further functional studies of important candidate MADS-box genes.

  8. Conceptual design and optimization methodology for box wing aircraft

    OpenAIRE

    Jemitola, Paul Olugbeji

    2012-01-01

    A conceptual design optimization methodology was developed for a medium range box wing aircraft. A baseline conventional cantilever wing aircraft designed for the same mis- sion and payload was also optimized alongside a baseline box wing aircraft. An empirical formula for the mass estimation of the fore and aft wings of the box wing aircraft was derived by relating conventional cantilever wings to box wing aircraft wings. The results indicate that the fore and aft wings would ...

  9. Box-Cox symmetric distributions and applications to nutritional data

    OpenAIRE

    Ferrari, Silvia L. P.; Fumes, Giovana

    2016-01-01

    We introduce the Box-Cox symmetric class of distributions, which is useful for modeling positively skewed, possibly heavy-tailed, data. The new class of distributions includes the Box-Cox t, Box-Cox Cole-Gree, Box-Cox power exponential distributions, and the class of the log-symmetric distributions as special cases. It provides easy parameter interpretation, which makes it convenient for regression modeling purposes. Additionally, it provides enough flexibility to handle outliers. The usefuln...

  10. Transformative Environmental Education: Stepping Outside the Curriculum Box

    Science.gov (United States)

    Johnston, Julie

    2009-01-01

    Environmental education has become trapped in the curriculum box. At a time when our students' generation is becoming trapped in a global warming box, their education needs to be rapidly adaptable to the changing state of their planet. Venturing outside the curriculum box takes courage, creativity, and a willingness to let nature serve as the…

  11. 76 FR 41411 - Group E Post Office Box Service

    Science.gov (United States)

    2011-07-14

    ... 111 Group E Post Office Box Service AGENCY: Postal Service\\TM\\. ACTION: Final rule. SUMMARY: The... administration for Group E (free) Post Office\\TM\\ (PO) box service. DATES: Effective Date: September 6, 2011. FOR... facilitate uniform administration for Group E (free) PO Box\\TM\\ service. The Postal Service received several...

  12. 75 FR 71642 - Group E Post Office Box Service

    Science.gov (United States)

    2010-11-24

    ... 111 Group E Post Office Box Service AGENCY: Postal Service\\TM\\. ACTION: Proposed rule. SUMMARY: The... administration for Group E (free) Post Office\\TM\\ (PO) Box service. DATES: We must receive your comments on or..., Washington, DC between 9 a.m. and 4 p.m., Monday through Friday. E-mail comments concerning the proposed box...

  13. 21 CFR 864.9185 - Blood grouping view box.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Blood grouping view box. 864.9185 Section 864.9185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... and Blood Products § 864.9185 Blood grouping view box. (a) Identification. A blood grouping view box...

  14. 31 CFR 515.326 - Custody of safe deposit boxes.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Custody of safe deposit boxes. 515... Definitions § 515.326 Custody of safe deposit boxes. Safe deposit boxes shall be deemed to be in the custody... upon the meaning of the term custody. ...

  15. 31 CFR 500.326 - Custody of safe deposit boxes.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Custody of safe deposit boxes. 500... Definitions § 500.326 Custody of safe deposit boxes. Safe deposit boxes shall be deemed to be in the custody... upon the meaning of the term custody. ...

  16. 30 CFR 18.49 - Connection boxes on machines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Connection boxes on machines. 18.49 Section 18..., AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES Construction and Design Requirements § 18.49 Connection boxes on machines. Connection boxes used to facilitate replacement...

  17. Using Origami Boxes to Explore Concepts of Geometry and Calculus

    Science.gov (United States)

    Wares, Arsalan

    2011-01-01

    The purpose of this classroom note is to provide an example of how a simple origami box can be used to explore important concepts of geometry and calculus. This article describes how an origami box can be folded, then it goes on to describe how its volume and surface area can be calculated. Finally, it describes how the box could be folded to…

  18. 49 CFR 230.102 - Tender plain bearing journal boxes.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Tender plain bearing journal boxes. 230.102... Locomotives and Tenders Running Gear § 230.102 Tender plain bearing journal boxes. Plain bearing journal boxes... expected to damage the bearing; or have a detrimental effect on the lubrication of the journal and bearing...

  19. 49 CFR 230.103 - Tender roller bearing journal boxes.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Tender roller bearing journal boxes. 230.103... Locomotives and Tenders Running Gear § 230.103 Tender roller bearing journal boxes. Tender roller bearing journal boxes shall be maintained in a safe and suitable condition. ...

  20. The Central Nervous System of Box Jellyfish

    DEFF Research Database (Denmark)

    Garm, Anders Lydik; Ekström, Peter

    2008-01-01

    of behaviors in the box jellyfish such as obstacle avoidance and navigation. The need to process the visual information and turn it into the appropriate behavior puts strong demands on the nervous system of box jellyfish, which appears more elaborate than in other cnidarians. Here, the central part...... of this nervous system is described. Each rhopalium holds a separate part of the CNS with 1,000 nerve cells and a large amount of neuropil. The rhopalial nervous system has several subsystems defined by the anatomy, location, and immunocytochemistry of the cells. Most of the subsystems connect to one or more...... of the eye types, and it is likely that the rhopalial nervous system accounts for most of the visual processing. The major part of the CNS is made up of a ring nerve encircling the bell shaped body. The ring nerve holds around 10,000 cells and is directly connected to all four rhopalial nervous systems...

  1. Fatal exit the automotive black box debate

    CERN Document Server

    Kowalick, Tom

    2005-01-01

    "Fatal Exit: The Automotive Black Box Debate cuts through thirty years of political wrangling and institutional biases to provide an argument for the Motor Vehicle Event Data Recorder (MVEDR). This automotive equivalent of an airplane's flight recorder or black box is intended to solve the mysteries of car crashes and improve the safety of our roads. The reader is taken inside the automotive industry and the government highway safety establishment to foster an understanding of the politics and the positions on all sides of this safety debate. The author takes an unbiased approach, chronologically presenting each argument and uncovering the agendas and mandates of each of the stakeholders." "This publication is essential reading for all consumers who need to have their voices heard on this critical issue, as well as for attorneys, public safety advocates, public policy administrators, engineers, automotive professionals, journalists, and insurance executives."--Jacket.

  2. Design and Optimize an Automatic Medicine Box

    OpenAIRE

    Lai, Lin; Wu, Shengmin

    2010-01-01

    Our work is to design an automatic and intelligent medicine box to help most people to take the medicine easily, especially for the arthritis, the elderly, the forgetful people and the kids. First, five different structures have been designed by CAD Inventor software. One of them, which can be carried out the most easily in reality, has been chosen to complete with a dynamic system. Considering the characteristic of medicine, there are two schemes in the structure designs are ideal. Several c...

  3. Can the box plot be improved?

    OpenAIRE

    Chamnein Choonpradub; Don McNeil

    2005-01-01

    Invented by Spear in 1952 and popularized by Tukey in 1977, the box plot is widely used for displaying and comparing samples of continuous observations. Despite its popularity, it is less effective for showing shape behaviour of distributions, particularly bimodality. Using robust estimators of data skewness and kurtosis to classify the distribution into categories, we suggest a simple enhancement for indicating bimodality, central peakedness, and skewness. We also suggest a new graphical met...

  4. The Spectra of Des S-Boxes

    Science.gov (United States)

    2014-06-01

    Properties of Cayley Graphs Associated with S-Box 8 BFs. . . . . 132 Table 6.51 The DES Functions with Ramanujan Cayley Graphs. . . . . . . . 136 Table...interesting case occurs when this inequality is not satisfied. Alexander Lubotzky et al. [89] coined the term Ramanujan graph for an r-regular graph in which...the largest eigenvalue other than λn = r is less than or equal to the Alon-Boppana bound. Ramanujan graphs are named after Indian mathematician

  5. Avionics Box Cold Plate Damage Prevention

    Science.gov (United States)

    Stambolian, Damon; Larcher, Steven; Henderson, Gena; Tran, Donald

    2011-01-01

    Over the years there have been several occurrences of damage to Space Shuttle Orbiter cold plates during removal and replacement of avionics boxes. Thus a process improvement team was put together to determine ways to prevent these kinds of damage. From this effort there were many solutions including, protective covers, training, and improved operations instructions. The focus of this paper is to explain the cold plate damage problem and the corrective actions for preventing future damage to aerospace avionics cold plate designs.

  6. Interferometric investigation of convection in plexiglas boxes

    Science.gov (United States)

    Koster, J. N.

    1983-09-01

    Real-time holographic interferometry is used to study free convection in cavities heated from below and bounded by Plexiglas windows. Advantages and shortcomings of this visualization technique applied to such Plexiglas boxes are discussed. As Plexiglas has a high temperature-dependent refractive index, temperature fields in the windows and the fluid layer are visualized. These visualizations furnished proof of a pronounced thermal influence of the walls on the flow pattern based on what we call “thermal memory” of Plexiglas.

  7. Monitoring Instrument for X-Ray Box

    CERN Document Server

    Cifuentes Ospina, Alberto; Kuehn, Susanne; Schaepe, Steffen; CERN. Geneva. EP Department

    2017-01-01

    A humidity and temperature readout instrument has been designed and implemented in order to monitor the X-Ray Box used for testing the silicon detectors prototypes of the ITk. The sensors are connected to an Arduino Mega board equipped with 16 analog inputs and a serial port to a computer. A user-friendly software has been also designed in order to give an easy access to all measurements.

  8. PCB-Based Break-Out Box

    Science.gov (United States)

    Lee, Jason H.

    2011-01-01

    Break-out boxes (BOBs) are necessary for all electrical integration/cable checkouts and troubleshooting. Because the price of a BOB is high, and no work can be done without one, often the procedure stops, simply waiting for a BOB. A less expensive BOB would take less time in the integration, testing, and troubleshooting process. The PCB-based BOB works and looks the same as a standard JPL BOB, called Gold Boxes. The only differences between the old BOB and the new PCB-based BOB is that the new one has 80 percent of its circuitry in a printed circuit board. This process reduces the time for fabrication, thus making the BOBs less expensive. Moreover, because of its unique design, the new BOBs can be easily assembled and fixed. About 80 percent of the new PCB-based BOB is in a $22 (at the time of this reporting) custom-designed, yet commercially available PCB. This device has been used successfully to verify that BOB cables were properly made. Also, upon completion, the BOB was beeped out via a multimeter to ensure that all sockets on the connectors were properly connected to the respective banana jack. When compared to the Gold Box BOBs, the new BOB has many advantages. It is much more cost efficient, it delivers equal usability at substantially lower cost of the BOB, and the Gold Box is much heavier when compared to the new BOB. The new BOB is also a bit longer and much more versatile in that connectors are easily changeable and if a banana jack is broken, it can be replaced instead of throwing away an entire BOB.

  9. Box fractal dimension in speckle images

    Science.gov (United States)

    Rabal, Héctor; Grumel, Eduardo; Cap, Nelly; Buffarini, Leandro; Trivi, Marcelo

    2017-06-01

    In this paper, we propose a generalization of the box fractal dimension in images by considering the curve obtained from its value as a function of the binarization threshold. This curve can be used to describe speckle patterns. We show some examples of both objective simulated and experimental and subjective speckle in some cases of interest. The concept can be extended for all types of images.

  10. Prohibiting Headgear for Safety in Amateur Boxing? Opinion of the Canadian Boxing Community: an Online Poll.

    Science.gov (United States)

    Dickinson, Philip; Rempel, Philip

    In 2013, the Amateur International Boxing Association (AIBA) introduced a rule banning headgear for male-senior open class boxers during competition. The AIBA has defended the rule change as motivated by safety and supported by internal unpublished studies. As a result, in 2018, the AIBA plans to universally prohibit headgear in competition: for all competitors (male and female), all ages and all levels. Within Canada, this ruling has generated controversy in the boxing community, yet there has been no overall measure of opinion. To address this, we instituted a voluntary, anonymous, online open-access poll to allow members of the boxing community to express their stance on headgear use in competition. In total, 636 responses were received. A total of 71.5 % of Canadian respondents believed headgear should be mandatory at all levels. Only 5.8 % agreed that headgear should be prohibited, as planned for 2018. Estimating results on a representative breakdown of boxing membership in Canada, a similar pattern emerged, whereby 68.2 % concurred with mandatory headgear while only 4.95 % supported its prohibition. Parents of boxers were almost unanimously against banning headgear, stating they would change sports as a result. Similarly, only 1.7 % of women believed headgear should be prohibited. The consensus of the Canadian boxing community largely opposes the rule changes that the AIBA has implemented. The results highlight risks posed to the long-term viability of the sport, if significant grassroots safety concerns are disregarded.

  11. The FRP1 F-box gene has different functions in sexuality, pathogenicity and metabolism in three fungal pathogens

    NARCIS (Netherlands)

    Jonkers, W.; Kan, van J.A.L.; Tijm, P.; Lee, Y.W.; Tudzynski, P.; Rep, M.; Michielse, C.B.

    2011-01-01

    Plant-pathogenic fungi employ a variety of infection strategies; as a result, fungi probably rely on different sets of proteins for successful infection. The F-box protein Frp1, only present in filamentous fungi belonging to the Sordariomycetes, Leotiomycetes and Dothideomycetes, is required for

  12. 49 CFR 178.512 - Standards for steel or aluminum boxes.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Standards for steel or aluminum boxes. 178.512... aluminum boxes. (a) The following are identification codes for steel or aluminum boxes: (1) 4A for a steel box; and (2) 4B for an aluminum box. (b) Construction requirements for steel or aluminum boxes are as...

  13. A white-box model of S-shaped and double S-shaped single-species population growth

    Directory of Open Access Journals (Sweden)

    Lev V. Kalmykov

    2015-05-01

    Full Text Available Complex systems may be mechanistically modelled by white-box modeling with using logical deterministic individual-based cellular automata. Mathematical models of complex systems are of three types: black-box (phenomenological, white-box (mechanistic, based on the first principles and grey-box (mixtures of phenomenological and mechanistic models. Most basic ecological models are of black-box type, including Malthusian, Verhulst, Lotka–Volterra models. In black-box models, the individual-based (mechanistic mechanisms of population dynamics remain hidden. Here we mechanistically model the S-shaped and double S-shaped population growth of vegetatively propagated rhizomatous lawn grasses. Using purely logical deterministic individual-based cellular automata we create a white-box model. From a general physical standpoint, the vegetative propagation of plants is an analogue of excitation propagation in excitable media. Using the Monte Carlo method, we investigate a role of different initial positioning of an individual in the habitat. We have investigated mechanisms of the single-species population growth limited by habitat size, intraspecific competition, regeneration time and fecundity of individuals in two types of boundary conditions and at two types of fecundity. Besides that, we have compared the S-shaped and J-shaped population growth. We consider this white-box modeling approach as a method of artificial intelligence which works as automatic hyper-logical inference from the first principles of the studied subject. This approach is perspective for direct mechanistic insights into nature of any complex systems.

  14. Nopaline-type Ti plasmid of Agrobacterium encodes a VirF-like functional F-box protein.

    Science.gov (United States)

    Lacroix, Benoît; Citovsky, Vitaly

    2015-11-20

    During Agrobacterium-mediated genetic transformation of plants, several bacterial virulence (Vir) proteins are translocated into the host cell to facilitate infection. One of the most important of such translocated factors is VirF, an F-box protein produced by octopine strains of Agrobacterium, which presumably facilitates proteasomal uncoating of the invading T-DNA from its associated proteins. The presence of VirF also is thought to be involved in differences in host specificity between octopine and nopaline strains of Agrobacterium, with the current dogma being that no functional VirF is encoded by nopaline strains. Here, we show that a protein with homology to octopine VirF is encoded by the Ti plasmid of the nopaline C58 strain of Agrobacterium. This protein, C58VirF, possesses the hallmarks of functional F-box proteins: it contains an active F-box domain and specifically interacts, via its F-box domain, with SKP1-like (ASK) protein components of the plant ubiquitin/proteasome system. Thus, our data suggest that nopaline strains of Agrobacterium have evolved to encode a functional F-box protein VirF.

  15. Reconciling White-Box and Black-Box Perspectives on Behavioral Self-adaptation

    DEFF Research Database (Denmark)

    Bruni, Roberto; Corradini, Andrea; Gadducci, Fabio

    2015-01-01

    This paper proposes to reconcile two perspectives on behavioral adaptation commonly taken at different stages of the engineering of autonomic computing systems. Requirements engineering activities often take a black-box perspective: A system is considered to be adaptive with respect...... to an environment whenever the system is able to satisfy its goals irrespectively of the environment perturbations. Modeling and programming engineering activities often take a white-box perspective: A system is equipped with suitable adaptation mechanisms and its behavior is classified as adaptive depending...... and possibly modify the adaptation requirements, models and programs of an autonomic system....

  16. Box codes of lengths 48 and 72

    Science.gov (United States)

    Solomon, G.; Jin, Y.

    1993-01-01

    A self-dual code length 48, dimension 24, with Hamming distance essentially equal to 12 is constructed here. There are only six code words of weight eight. All the other code words have weights that are multiples of four and have a minimum weight equal to 12. This code may be encoded systematically and arises from a strict binary representation of the (8,4;5) Reed-Solomon (RS) code over GF (64). The code may be considered as six interrelated (8,7;2) codes. The Mattson-Solomon representation of the cyclic decomposition of these codes and their parity sums are used to detect an odd number of errors in any of the six codes. These may then be used in a correction algorithm for hard or soft decision decoding. A (72,36;15) box code was constructed from a (63,35;8) cyclic code. The theoretical justification is presented herein. A second (72,36;15) code is constructed from an inner (63,27;16) Bose Chaudhuri Hocquenghem (BCH) code and expanded to length 72 using box code algorithms for extension. This code was simulated and verified to have a minimum distance of 15 with even weight words congruent to zero modulo four. The decoding for hard and soft decision is still more complex than the first code constructed above. Finally, an (8,4;5) RS code over GF (512) in the binary representation of the (72,36;15) box code gives rise to a (72,36;16*) code with nine words of weight eight, and all the rest have weights greater than or equal to 16.

  17. MADS-Box Transcription Factor VdMcm1 Regulates Conidiation, Microsclerotia Formation, Pathogenicity, and Secondary Metabolism of Verticillium dahliae

    OpenAIRE

    Xiong, Dianguang; Wang, Yonglin; Tian, Longyan; Tian, Chengming

    2016-01-01

    Verticillium dahliae, a notorious phytopathogenic fungus, causes vascular wilt diseases in many plant species resulting in devastating yield losses worldwide. Due to its ability to colonize plant xylem and form microsclerotia, V. dahliae is highly persistent and difficult to control. In this study, we show that the MADS-box transcription factor VdMcm1 is a key regulator of conidiation, microsclerotia formation, virulence, and secondary metabolism of V. dahliae. In addition, our findings sugge...

  18. Can the box plot be improved?

    Directory of Open Access Journals (Sweden)

    Chamnein Choonpradub

    2005-05-01

    Full Text Available Invented by Spear in 1952 and popularized by Tukey in 1977, the box plot is widely used for displaying and comparing samples of continuous observations. Despite its popularity, it is less effective for showing shape behaviour of distributions, particularly bimodality. Using robust estimators of data skewness and kurtosis to classify the distribution into categories, we suggest a simple enhancement for indicating bimodality, central peakedness, and skewness. We also suggest a new graphical method for displaying confidence intervals when comparing several samples of continuous data.

  19. Smart Distribution Boxes, Complete Energy Management

    Energy Technology Data Exchange (ETDEWEB)

    Platise, Uros

    2010-09-15

    Present households demand side management implementations are turning conventional appliances into smart ones to support auto demand (AutoDR) response function. Present concept features a direct link between the power meters and appliances. In this paper new concept and example of implementation of a so-called Smart Distribution Box (SmartDB) is represented for complete energy and power management. SmartDBs, as an intermediate layer, are extending smart grid power meter functionality to support AutoDR with fast and guaranteed response times, distributed power sources, and besides provide full control over energy management and extra safety functions to the consumers.

  20. Keller-box method and its application

    CERN Document Server

    Prasad, Kerehalli V

    2014-01-01

    Most of the problems arising in science and engineering are nonlinear. They are inherently difficult to solve. Traditional analytical approximations are valid only for weakly nonlinear problems, and often break down for problems with strong nonlinearity. This book presents the current theoretical developments and applications of Keller-Box method to nonlinear problems. The first half of the bookaddresses basic concepts to understand the theoretical framework for the method. In the second half of the book, the authorsgive a number of examples of coupled nonlinear problems that have been solved

  1. LHC Crab Cavity Coupler Test Boxes

    CERN Document Server

    Mitchell, James; Burt, Graeme; Calaga, Rama; Macpherson, Alick; Montesinos, Eric; Silva, Subashini; Tutte, Adam; Xiao, Binping

    2016-01-01

    The LHC double quarter wave (DQW) crab cavities have two different types of Higher Order Mode (HOM) couplers in addition to a fundamental power coupler (FPC). The FPC requires conditioning, so to achieve this we have designed a radio-frequency (RF) quarter wave resonator to provide high transmission between two opposing FPCs. For the HOM couplers we must ensure that the stop-band filter is positioned at the cavity frequency and that peak transmission occurs at the same frequencies as the strongest HOMs. We have designed two test boxes which preserve the cavity spectral response in order to test the couplers.

  2. A (72, 36; 15) box code

    Science.gov (United States)

    Solomon, G.

    1993-01-01

    A (72,36;15) box code is constructed as a 9 x 8 matrix whose columns add to form an extended BCH-Hamming (8,4;4) code and whose rows sum to odd or even parity. The newly constructed code, due to its matrix form, is easily decodable for all seven-error and many eight-error patterns. The code comes from a slight modification in the parity (eighth) dimension of the Reed-Solomon (8,4;5) code over GF(512). Error correction uses the row sum parity information to detect errors, which then become erasures in a Reed-Solomon correction algorithm.

  3. Teaching Outside the Box: ARL Librarians' Integration of the "One- Box" into Student Instruction

    Science.gov (United States)

    Kulp, Christina; McCain, Cheryl; Scrivener, Laurie

    2014-01-01

    This article reports the results of a survey that targeted reference and instruction librarians who work at libraries that are members of the Asso- ciation of Research Libraries (ARL). Respondents were asked to indicate whether or not they teach students to use the one-box tool, and why or why not. Based on the responses of the 352 librarians who…

  4. The Design of the Orthogonal Box Cavity

    Energy Technology Data Exchange (ETDEWEB)

    Moretti, Alfred; /Fermilab

    2010-09-15

    The muon collider and/or the neutrino factory require large accelerating electric field gradients immersed in large (3 to 6 T) solenoidal magnetic fields for ionization cooling of muon beams. Our original vacuum breakdown study demonstrated a loss of achievable peak accelerating gradient in solenoidal magnetic fields by a factor 2 or greater. The Muon Collaboration has developed a theory of a method to suppress high electric field breakdown in vacuum cavities needed for a Muon collider or neutrino factory. It has been shown in our studies and by others that high gradient electric field emitted electrons (dark current) are the primary cause of breakdown. A DC magnetic field orthogonal to the RF electric accelerating field prevents dark current high field emitted electrons from traveling across the accelerating gap and then will prevent breakdown. We have decided to test this theory by building a special cavity in the shape of vacuum box. Figure 1 is a simplified view of the cavity design. The design is based on an 805 MHz WR975 waveguide cavity resonating in the TE{sub 101} mode. For the TE{sub 101} mode the resonant frequency f{sub 0} is given by the relationship f{sub 0} = c[(I/a){sup 2} + (m/b){sup 2} + (n/d){sup 2}]{sup 0.5}/2 where a and d are the lengths of the base sides and b is the height of the box in MKS units and c is the velocity of light.

  5. Research of intelligent bus coin box

    Science.gov (United States)

    Xin, Shihao

    2017-03-01

    In the energy-saving emission reduction of the social context, in response to low-carbon travel, buses become the majority of people choose. We have designed this sorting machine for the present situation that the bus company has received a large amount of mixed zero coins and employed a large amount of manpower to sort out and lower the efficiency. Its function is to separate the coins and notes mixed, and the coins sort storage, the display shows the value of the received coins, so that the whole mechanized inventory classification, reduce the cost of clearing up and improve the efficiency of zero cash recycling, use Simple mechanical principles for classification, to be efficient, accurate and practical. Really meet the current city bus companies, commerce and banking and other industries in order to zero notes, zero coins in the actual demand. The size and specification of this machine are designed according to the size of the bus coin box. It is suitable for almost all buses. It can be installed in the coin box directly, real-time sorting and real-time counting. The difficulty of clearing change.

  6. Hairy black holes in a box

    Energy Technology Data Exchange (ETDEWEB)

    Basu, Pallab [International Center for Theoretical Sciences,IISc Campus, Bangalore 560012 (India); Krishnan, Chethan; Subramanian, P.N. Bala [Center for High Energy Physics, Indian Institute of Science,Bangalore 560012 (India)

    2016-11-08

    We do a systematic study of the phases of gravity coupled to an electromagnetic field and charged scalar in flat space, with box boundary conditions. The scalar-less box has previously been investigated by Braden, Brown, Whiting and York (and others) before AdS/CFT and we elaborate and extend their results in a language more familiar from holography. The phase diagram of the system is analogous to that of AdS black holes, but we emphasize the differences and explain their origin. Once the scalar is added, we show that the system admits both boson stars as well as hairy black holes as solutions, providing yet another way to evade flat space no-hair theorems. Furthermore both these solutions can exist as stable phases in regions of the phase diagram. The final picture of the phases that emerges is strikingly similar to that found recently for holographic superconductors in global AdS, http://arxiv.org/abs/1602.07211. Our construction lays bare certain previously unnoticed subtleties associated to the definition quasi-local charges for gravitating scalar fields in finite regions.

  7. Flexible bulb large storage box hydrogen maser

    Science.gov (United States)

    Reinhardt, V.

    1973-01-01

    The principal limitation on the accuracy of the hydrogen maser as a primary frequency standard has been the irreproducibility of the frequency shift caused by collisions of the radiating atoms with the walls of the vessel containing them. The flexible bulb-large storage box hydrogen maser allows correction for this wall shift within a single device, sidestepping the reproducibility problem, and reducing the frequency error from the wall shift to the level imposed by the device's stability. The principles of the device are discussed including the flexible bulb technique and the complications caused by a multiple region storage bulb. The stability of the device is discussed including a comparison with an ordinary hydrogen maser. Data is presented from a working flexible bulb-large storage box hydrogen maser demonstrating the feasibility of the device and showing some of its operating characteristics. The flexibility of the device is demonstrated by showing how the device's added degrees of freedom allow measurement of parameters unmeasurable in an ordinary hydrogen maser.

  8. A Group Action Method for Construction of Strong Substitution Box

    Science.gov (United States)

    Jamal, Sajjad Shaukat; Shah, Tariq; Attaullah, Atta

    2017-06-01

    In this paper, the method to develop cryptographically strong substitution box is presented which can be used in multimedia security and data hiding techniques. The algorithm of construction depends on the action of a projective general linear group over the set of units of the finite commutative ring. The strength of substitution box and ability to create confusion is assessed with different available analyses. Moreover, the ability of resistance against malicious attacks is also evaluated. The substitution box is examined by bit independent criterion, strict avalanche criterion, nonlinearity test, linear approximation probability test and differential approximation probability test. This substitution box is equated with well-recognized substitution boxes such as AES, Gray, APA, S8, prime of residue, Xyi and Skipjack. The comparison shows encouraging results about the strength of the proposed box. The majority logic criterion is also calculated to analyze the strength and its practical implementation.

  9. Visual pigments of the box jellyfish species Chiropsella bronzie

    DEFF Research Database (Denmark)

    O*Connor, Megan; Garm, Anders Lydik; Marshall, Justin

    2010-01-01

    Box jellyfish (Cubomedusae) possess a unique visual system comprising 24 eyes of four morphological types. Moreover, box jellyfish display several visually guided behaviours, including obstacle avoidance and light-shaft attractance. It is largely unknown what kind of visual information box...... jellyfish use for carrying out these behaviours. Brightness contrast is almost certainly involved, but it is also possible that box jellyfish extract colour information from their surroundings. The possible presence of colour vision in box jellyfish has previously been investigated using behavioural......, electrophysiological and immunohistochemical methods. However, the results from these studies are to some degree conflicting and inconclusive. Here, we present results from an investigation into the visual system of the box jellyfish Chiropsella bronzie, using microspectrophotometry and immunohistochemistry. Our...

  10. Deep Cropping via Attention Box Prediction and Aesthetics Assessment

    OpenAIRE

    Wang, Wenguan; Shen, Jianbing

    2017-01-01

    We model the photo cropping problem as a cascade of attention box regression and aesthetic quality classification, based on deep learning. A neural network is designed that has two branches for predicting attention bounding box and analyzing aesthetics, respectively. The predicted attention box is treated as an initial crop window where a set of cropping candidates are generated around it, without missing important information. Then, aesthetics assessment is employed to select the final crop ...

  11. Prospective Assessment of Inpatient Boxed Warning Prescriber Adherence.

    Science.gov (United States)

    Kloet, Megan A; Lohr, Brian R; Smithburger, Pamela L; Seybert, Amy L; Kane-Gill, Sandra L

    2017-03-01

    To evaluate medication boxed warning nonadherence in the inpatient setting. This was a prospective cohort quality improvement project approved by our institution's Total Quality Council. General medicine and ICU patients 18 years and older were included if they were cared for by a prescriber-led multidisciplinary team that included a pharmacist. Patients were evaluated for medication orders with an actionable boxed warning; if boxed warning nonadherence occurred, the physician's reason was determined. Patients with boxed warning nonadherence were monitored for adverse drug reactions until discharge. A total of 393 patients (224 general medicine and 169 ICU) were evaluated for nonadherence to 149 actionable boxed warnings. There were 293 drugs (175 general medicine and 118 ICU) with boxed warnings prescribed, and more than 50% of these were medications restarted from home. A total of 23 boxed warning nonadherences occurred in general medicine patients, and NSAIDs accounted for 81% of these events. ICU patients experienced 11 boxed warning nonadherences, with nearly 54% from anti-infectives and immunosuppressants. Antipsychotics were the most commonly ordered boxed warning medication class in ICU patients. Reasons for nonadherence included knowledge deficit and an acceptable risk-to-benefit ratio. Two adverse drug reactions occurred from boxed warning nonadherences, both because of a drug-drug interaction. Boxed warning nonadherence is a concern in the inpatient setting, specifically with NSAID use in general medicine patients and antipsychotic use in ICU patients. More than half of boxed warning nonadherence occurred in medications restarted from home, which emphasizes the need for medication evaluation during transitions of care.

  12. Grey-box modelling of pharmacokinetic/pharmacodynamic systems

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Jacobsen, Judith L; Pedersen, Oluf

    2004-01-01

    Grey-box pharmacokinetic/pharmacodynamic (PK/PD) modelling is presented as a promising way of modelling PK/PD systems. The concept behind grey-box modelling is based on combining physiological knowledge along with information from data in the estimation of model parameters. Grey-box modelling con...... in order to describe the complicated in vivo system of insulin and glucose following an IVGTT....

  13. An Improved Method of Manufacturing Corrugated Boxes: Lateral Corrugator

    Energy Technology Data Exchange (ETDEWEB)

    Frank C. Murray Ph.D.; , Roman Popil Ph.D.; Michael Shaepe (formerly with IPST, now at Cargill. Inc)

    2008-12-18

    Paper physicists have known that a corrugated box constructed from outer liner sheets having a predominant fiber orientation aligned with the corrugating flute direction would have higher stiffness and crush resistance (per unit of fiber weight) than the conventional box construction. Such increased performance per unit of fiber weight could result in fiber reduction and energy savings for boxes having equivalent performance specifications. The goal of this project was to develop and demonstrate a commercially viable lateral corrugating process. This included designing and building a pilot lateral corrugator, testing and evaluating pilot machine made boxes, and developing a strategy for commercialization.

  14. Cyclin-like F-box protein plays a role in growth and development of the three model species Medicago truncatula, Lotus japonicus, and Arabidopsis thaliana

    Directory of Open Access Journals (Sweden)

    Boycheva I

    2015-08-01

    Full Text Available Irina Boycheva,1 Valya Vassileva,2 Miglena Revalska,1 Grigor Zehirov,2 Anelia Iantcheva1 1Department of Functional Genetics Legumes, 2AgroBioInstitute, Department of Plant Stress Molecular Biology, Institute of Plant Physiology and Genetics, Sofia, Bulgaria Abstract: In eukaryotes, F-box proteins are one of the main components of the SCF complex that belongs to the family of ubiquitin E3 ligases, which catalyze protein ubiquitination and maintain the balance between protein synthesis and degradation. In the present study, we clarified the role and function of the gene encoding cyclin-like F-box protein from Medicago truncatula using transgenic plants of the model species M. truncatula, Lotus japonicas, and Arabidopsis thaliana generated by Agrobacterium-mediated transformation. Morphological and transcriptional analyses combined with flow cytometry and histochemistry demonstrated the participation of this protein in many aspects of plant growth and development, including processes of indirect somatic embryogenesis and symbiotic nodulation. The cyclin-like F-box gene showed expression in all plant organs and tissues comprised of actively dividing cells. The observed variations in root and hypocotyl growth, leaf and silique development, ploidy levels, and leaf parameters in the obtained transgenic lines demonstrated the effects of this gene on organ development. Furthermore, knockdown of cyclin-like F-box led to accumulation of higher levels of the G2/M transition-specific gene cyclin B1:1 (CYCB1:1, suggesting its possible role in cell cycle control. Together, the collected data suggest a similar role of the cyclin-like F-box protein in the three model species, providing evidence for the functional conservation of the studied gene. Keywords: cyclin-like F-box, model legumes, Arabidopsis thaliana, plant growth, plant development, cell cycle

  15. Factors Affecting Microcuttings of Stevia Using a Mist-Chamber Propagation Box

    Directory of Open Access Journals (Sweden)

    Mohamad Osman

    2013-01-01

    Full Text Available Stevia rebaudiana Bertoni is a member of Compositae family. Stevia plant has zero calorie content and its leaves are estimated to be 300 times sweeter than sugar. This plant is believed to be the most ideal substitute for sugar and important to assist in medicinal value especially for diabetic patients. In this study, microcutting techniques using a mist-chamber propagation box were used as it was beneficial for propagation of Stevia and gave genetic uniformity to the plant. The effects of different treatments on root stimulation of Stevia in microcuttings technique were evaluated. Treatments studied were different sizes of shoot cuttings, plant growth regulators, lights, and shades. Data logger was used to record the mean value of humidity (>90% RH, light intensity (673–2045 lx, and temperature (28.6–30.1°C inside the mist-chamber propagation box. From analysis of variance, there were significant differences between varieties and treatments in parameters studied (P<0.05. For the size of shoot cuttings treatment, 6 nodes cuttings were observed to increase root number. As compared to control, shoot cuttings treated with indole butyric acid (IBA had better performance regarding root length. Yellow light and 50% shade treatments showed higher root and leaf number and these conditions can be considered as crucial for potential propagation of Stevia.

  16. Factors Affecting Microcuttings of Stevia Using a Mist-Chamber Propagation Box

    Science.gov (United States)

    Osman, Mohamad; Samsudin, Nur Syamimi; Faruq, Golam

    2013-01-01

    Stevia rebaudiana Bertoni is a member of Compositae family. Stevia plant has zero calorie content and its leaves are estimated to be 300 times sweeter than sugar. This plant is believed to be the most ideal substitute for sugar and important to assist in medicinal value especially for diabetic patients. In this study, microcutting techniques using a mist-chamber propagation box were used as it was beneficial for propagation of Stevia and gave genetic uniformity to the plant. The effects of different treatments on root stimulation of Stevia in microcuttings technique were evaluated. Treatments studied were different sizes of shoot cuttings, plant growth regulators, lights, and shades. Data logger was used to record the mean value of humidity (>90% RH), light intensity (673–2045 lx), and temperature (28.6–30.1°C) inside the mist-chamber propagation box. From analysis of variance, there were significant differences between varieties and treatments in parameters studied (P Stevia. PMID:24470797

  17. Design Research: Six Views in a Box

    DEFF Research Database (Denmark)

    2011-01-01

    This book is a report from a class on design research at the Danish Design School. Ten students had ten weeks to conduct design research based on approaches, methods and techniques from co-design focusing on the Alzheimer’s disease as experienced by people with Alzheimer’s, their relatives...... and close relations, and professional caretakers. Alzheimer's destroys brain cells, causing memory loss and problems with thinking and behavior severe enough to affect work, lifelong hobbies and social life. As Alzheimer’s is a fatal disease that affects many people, there is a strong interest in finding...... professional organizations in a user-driven approach to explore and learn what it means to identify and admit that a person has Alzheimer’s. Apart from making contributions to the common box, the students have written reports in which they reflect on their work both in relation to the design research process...

  18. Box ladders in a noninteger dimension

    Science.gov (United States)

    Gonzalez, I.; Kondrashuk, I. N.

    2013-11-01

    We construct a family of triangle-ladder diagrams that can be calculated using the Belokurov-Usyukina loop reduction technique in d= 4-2ɛ dimensions. The main idea of the approach we propose is to generalize this loop reduction technique existing in d= 4 dimensions. We derive a recurrence relation between the result for an L-loop triangle-ladder diagram of this family and the result for an (L- 1)-loop triangleladder diagram of the same family. Because the proposed method combines analytic and dimensional regularizations, we must remove the analytic regularization at the end of the calculation by taking the double uniform limit in which the parameters of the analytic regularization vanish. In the position space, we obtain a diagram in the left-hand side of the recurrence relations in which the rung indices are 1 and all other indices are 1 - ɛ in this limit. Fourier transforms of diagrams of this type give momentum space diagrams with rung indices 1 - ɛ and all other indices 1. By a conformal transformation of the dual space image of this momentum space representation, we relate such a family of triangle-ladder momentum diagrams to a family of box-ladder momentum diagrams with rung indices 1 - ɛ and all other indices 1. Because any diagram from this family is reducible to a one-loop diagram, the proposed generalization of the Belokurov-Usyukina loop reduction technique to a noninteger number of dimensions allows calculating this family of box-ladder diagrams in the momentum space explicitly in terms of Appell's hypergeometric function F 4 without expanding in powers of the parameter ɛ in an arbitrary kinematic region in the momentum space.

  19. Chironex fleckeri (Box Jellyfish) Venom Proteins

    Science.gov (United States)

    Brinkman, Diane L.; Konstantakopoulos, Nicki; McInerney, Bernie V.; Mulvenna, Jason; Seymour, Jamie E.; Isbister, Geoffrey K.; Hodgson, Wayne C.

    2014-01-01

    The box jellyfish Chironex fleckeri produces extremely potent and rapid-acting venom that is harmful to humans and lethal to prey. Here, we describe the characterization of two C. fleckeri venom proteins, CfTX-A (∼40 kDa) and CfTX-B (∼42 kDa), which were isolated from C. fleckeri venom using size exclusion chromatography and cation exchange chromatography. Full-length cDNA sequences encoding CfTX-A and -B and a third putative toxin, CfTX-Bt, were subsequently retrieved from a C. fleckeri tentacle cDNA library. Bioinformatic analyses revealed that the new toxins belong to a small family of potent cnidarian pore-forming toxins that includes two other C. fleckeri toxins, CfTX-1 and CfTX-2. Phylogenetic inferences from amino acid sequences of the toxin family grouped CfTX-A, -B, and -Bt in a separate clade from CfTX-1 and -2, suggesting that the C. fleckeri toxins have diversified structurally and functionally during evolution. Comparative bioactivity assays revealed that CfTX-1/2 (25 μg kg−1) caused profound effects on the cardiovascular system of anesthetized rats, whereas CfTX-A/B elicited only minor effects at the same dose. Conversely, the hemolytic activity of CfTX-A/B (HU50 = 5 ng ml−1) was at least 30 times greater than that of CfTX-1/2. Structural homology between the cubozoan toxins and insecticidal three-domain Cry toxins (δ-endotoxins) suggests that the toxins have a similar pore-forming mechanism of action involving α-helices of the N-terminal domain, whereas structural diversification among toxin members may modulate target specificity. Expansion of the cnidarian toxin family therefore provides new insights into the evolutionary diversification of box jellyfish toxins from a structural and functional perspective. PMID:24403082

  20. Sound radiation characteristics of a box-type structure

    Science.gov (United States)

    Ran Lin, Tian; Pan, Jie

    2009-09-01

    The finite element and boundary element methods are employed in this study to investigate the sound radiation characteristics of a box-type structure. It has been shown [T.R. Lin, J. Pan, Vibration characteristics of a box-type structure, Journal of Vibration and Acoustics, Transactions of ASME 131 (2009) 031004-1-031004-9] that modes of natural vibration of a box-type structure can be classified into six groups according to the symmetry properties of the three panel pairs forming the box. In this paper, we demonstrate that such properties also reveal information about sound radiation effectiveness of each group of modes. The changes of radiation efficiencies and directivity patterns with the wavenumber ratio (the ratio between the acoustic and the plate bending wavenumbers) are examined for typical modes from each group. Similar characteristics of modal radiation efficiencies between a box structure and a corresponding simply supported panel are observed. The change of sound radiation patterns as a function of the wavenumber ratio is also illustrated. It is found that the sound radiation directivity of each box mode can be correlated to that of elementary sound sources (monopole, dipole, etc.) at frequencies well below the critical frequency of the plates of the box. The sound radiation pattern on the box surface also closely related to the vibration amplitude distribution of the box structure at frequencies above the critical frequency. In the medium frequency range, the radiated sound field is dominated by the edge vibration pattern of the box. The radiation efficiency of all box modes reaches a peak at frequencies above the critical frequency, and gradually approaches unity at higher frequencies.

  1. A W-box is required for full expression of the SA-responsive gene SFR2.

    Science.gov (United States)

    Rocher, Anne; Dumas, Christian; Cock, J Mark

    2005-01-03

    Transcripts of SFR2, a member of the S family of receptor kinase genes, accumulate rapidly in Brassica oleracea leaves in response to wounding, bacterial infection and following treatment with salicylic acid (SA). Expression of a chimeric gene consisting of the SFR2 5' flanking sequence fused to the gusA reporter gene is also induced in wounded and SA-treated Arabidopsis plants indicating that the observed response is conferred by the SFR2 promoter. We show here that, in Arabidopsis plants carrying the salicylate hydroxylase (NahG) transgene, wound induction of the SFR2 promoter-gusA reporter fusion was abolished, indicating that, as has previously been shown for the response to bacterial infection, SA is required for the response to wounding. Deletion analysis of the SFR2 promoter identified a region necessary for full expression following SA treatment. This region, which includes two putative W-boxes, is conserved in the promoter of the Arabidopsis SFR2 homologue, ARK3. Deletion of a 12 bp region containing the two W-box motifs reduced the response to SA treatment. Tandem repeats of the W-box-containing element fused upstream of a CaMV 35S minimal promoter enhanced reporter gene expression in transgenic Arabidopsis both in the absence and presence of SA. Gel-mobility shift assays showed that Arabidopsis leaf extracts contained factors that bound to a fragment of the promoter spanning the putative W-boxes and that a fragment in which these motifs were mutated was unable to compete for binding. In summary, induction of the SFR2 promoter in response to bacterial infection and wounding requires SA, and full expression of the induced gene requires the presence of a functional element containing W-box motifs in the SFR2 promoter. The involvement of two W-boxes indicates that transcription factors of the WRKY family may play a key role in mediating these responses.

  2. A Comparison of Energy Expenditure During "Wii Boxing" Versus Heavy Bag Boxing in Young Adults.

    Science.gov (United States)

    Perusek, Kristen; Sparks, Kenneth; Little, Kathleen; Motley, Mary; Patterson, Sheila; Wieand, Jennifer

    2014-02-01

    Traditional computer videogames are sedentary, whereas new computer videogames, such as the Nintendo(®) (Redmond, WA) "Wii™ Sports" games, allow users to physically interact while playing the sport. Energy expenditure (EE), heart rate (HR), and rating of perceived exertion (RPE) during heavy bag boxing versus the Nintendo "Wii Boxing" game were compared. Fifteen males and 14 females (mean age, 25.6 years; height, 171.3 cm; weight, 71.8 kg) randomly selected (by a coin toss) heavy bag boxing or "Wii Boxing" for their first test session and completed the other protocol at their second session at least 2 days later. Each session lasted for a total duration of 30 minutes and consisted of 10 3-minute exercise bouts with measurements of HR, RPE, and EE obtained from indirect calorimetry. A paired-samples t test was used to analyze the results. Significant differences were found for HR (bag, 156 beats per minute; Wii, 138 beats per minute; P=0.001) and RPE (bag, 13.8; Wii, 11.4; P=0.0001) but not for EE (bag, 8.0 kcal/minute; Wii, 7.1 kcal/minute; bag, 241 total kcal; Wii, 213 total kcal; P=0.078). The results suggest that computer active videogames, such as the Nintendo Wii, have the potential to provide similar EE as their traditional forms of exercise and may be a sufficient replacement for traditional target HR zone activities, especially in less fit individuals. Further research is needed to compare EE for different "Wii Sports" games with those for their traditional forms of exercise.

  3. Dream Box Learning. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2013

    2013-01-01

    "DreamBox Learning" is a supplemental online mathematics program that provides adaptive instruction for students in grades K-5 and focuses on number and operations, place value, and number sense. The What Works Clearinghouse (WWC) identified one study of "DreamBox Learning" that both falls within the scope of the Elementary…

  4. 49 CFR 230.101 - Steam locomotive driving journal boxes.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Steam locomotive driving journal boxes. 230.101... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders Running Gear § 230.101 Steam locomotive driving journal boxes. (a) Driving journal...

  5. Creative Underachievers: Children Who Are Too out of the Box

    Science.gov (United States)

    Rimm, Sylvia

    2015-01-01

    Educators in the field of gifted education attempt to not only accelerate curriculum for their students, but also to encourage and expand their critical and creative thinking. They often explain this creative approach to students as "out-of-the-box" thinking. "The box" is an effective analogy to help children understand how to…

  6. A System for Cooling inside a Glove Box

    Science.gov (United States)

    Sanz, Martial

    2010-01-01

    An easy, efficient, reliable, and low-cost method of constructing a cooling system using a simple circulating pump is described. The system is employed in conjunction with an inert atmosphere glove box to achieve the synthesis of air- and moisture-sensitive compounds inside the glove box at controlled, low temperatures without contaminating the…

  7. Using Willie's Acid-Base Box for Blood Gas Analysis

    Science.gov (United States)

    Dietz, John R.

    2011-01-01

    In this article, the author describes a method developed by Dr. William T. Lipscomb for teaching blood gas analysis of acid-base status and provides three examples using Willie's acid-base box. Willie's acid-base box is constructed using three of the parameters of standard arterial blood gas analysis: (1) pH; (2) bicarbonate; and (3) CO[subscript…

  8. Faster Black-Box Algorithms Through Higher Arity Operators

    DEFF Research Database (Denmark)

    Doerr, Benjamin; Johannsen, Daniel; Kötzing, Timo

    2011-01-01

    We extend the work of Lehre and Witt (GECCO 2010) on the unbiased black-box model by considering higher arity variation operators. In particular, we show that already for binary operators the black-box complexity of LeadingOnes drops from (n2) for unary operators to O(n log n). For OneMax, the (n...

  9. Getting started with Oracle VM VirtualBox

    CERN Document Server

    Dash, Pradyumna

    2013-01-01

    A step-by-step guide that will show you how to install, configure, and manage VirtualBox.This book is for system administrators, technical architects, and virtualization enthusiasts who want to learn how to set up a virtual machine. Knowledge of the Linux environment is expected. Prior experience with VirtualBox or knowledge of virtualization is not required.

  10. Modelling of Box Type Solar Cooker Performance in a Tropical ...

    African Journals Online (AJOL)

    Thermal performance model of box type solar cooker with loaded water is presented. The model was developed using the method of Funk to estimate cooking power in terms of climatic and design parameters for box type solar cooker in a tropical environment. Coefficients for each term used in the model were determined ...

  11. Current implementation of advance encryption standard (AES) S-Box

    African Journals Online (AJOL)

    Although the attack on cryptosystem is still not severe, the development of the scheme is still ongoing especially for the design of S-Box. Two main approach has beenused, which are heuristic method and algebraic method. Algebraic method as in current AES implementation has been proven to be the most secure S-Box ...

  12. 30 CFR 18.43 - Explosion-proof splice boxes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Explosion-proof splice boxes. 18.43 Section 18.43 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION... Design Requirements § 18.43 Explosion-proof splice boxes. Internal connections shall be rigidly held and...

  13. 30 CFR 18.42 - Explosion-proof distribution boxes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Explosion-proof distribution boxes. 18.42 Section 18.42 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING... and Design Requirements § 18.42 Explosion-proof distribution boxes. (a) A cable passing through an...

  14. Lightweight S-Box Architecture for Secure Internet of Things

    Directory of Open Access Journals (Sweden)

    A. Prathiba

    2018-01-01

    Full Text Available Lightweight cryptographic solutions are required to guarantee the security of Internet of Things (IoT pervasiveness. Cryptographic primitives mandate a non-linear operation. The design of a lightweight, secure, non-linear 4 × 4 substitution box (S-box suited to Internet of Things (IoT applications is proposed in this work. The structure of the 4 × 4 S-box is devised in the finite fields GF (24 and GF ((222. The finite field S-box is realized by multiplicative inversion followed by an affine transformation. The multiplicative inverse architecture employs Euclidean algorithm for inversion in the composite field GF ((222. The affine transformation is carried out in the field GF (24. The isomorphic mapping between the fields GF (24 and GF ((222 is based on the primitive element in the higher order field GF (24. The recommended finite field S-box architecture is combinational and enables sub-pipelining. The linear and differential cryptanalysis validates that the proposed S-box is within the maximal security bound. It is observed that there is 86.5% lesser gate count for the realization of sub field operations in the composite field GF ((222 compared to the GF (24 field. In the PRESENT lightweight cipher structure with the basic loop architecture, the proposed S-box demonstrates 5% reduction in the gate equivalent area over the look-up-table-based S-box with TSMC 180 nm technology.

  15. Heart Rate and Liking During "Kinect Boxing" Versus "Wii Boxing": The Potential for Enjoyable Vigorous Physical Activity Videogames.

    Science.gov (United States)

    Sanders, Gabriel J; Peacock, Corey A; Barkley, Jacob E; Gish, Brian; Brock, Scott; Volpenhein, Josh

    2015-08-01

    Nintendo(®) (Kyoto, Japan) "Wii™ Sports Boxing" ("Wii Boxing") and Xbox(®) (Microsoft, Redmond, WA) "Kinect(®) Sports Boxing" ("Kinect Boxing") are both boxing simulation videogames that are available for two different active videogame (AVG) systems. Although these AVGs are similar, the style of gameplay required is different (i.e., upper body only versus total body movements) and may alter physical activity intensity and one's preference for playing one game over the other. AVGs that elicit the greatest physiologic challenge and are preferred by users should be identified in an effort to enhance the efficacy of physical activity interventions and programs that include AVGs. The mean heart rate (HRmean) and peak heart rate (HRpeak) for 27 adults (22.7±4.2 years old) were recorded during four 10-minute conditions: seated rest, treadmill walking at 3 miles/hour, "Wii Boxing," and "Kinect Boxing." Upon completion of all four conditions, participants indicated which condition they preferred, and HRmean and HRpeak were calculated as a percentage of age-predicted maximum heart rate to classify physical activity intensity for the three activity conditions (treadmill, "Wii Boxing," and "Kinect Boxing"). "Kinect Boxing" significantly (P<0.001) increased percentage HRmean (64.1±1.6 percent of age-predicted maximum) and percentage HRpeak (76.5±1.9 percent) above all other conditions: Wii HRmean, 53.0±1.2 percent; Wii HRpeak, 61.8±1.5 percent; treadmill HRmean, 52.4±1.2 percent; treadmill HRpeak, 55.2±2.2 percent. Percentage HRpeak for "Kinect Boxing" was great enough to be considered a vigorous-intensity physical activity. There was no difference (P=0.55) in percentage HRmean between "Wii Boxing" and treadmill walking. Participants also preferred "Kinect Boxing" (P<0.001; n=26) to all other conditions ("Wii Boxing," n=1; treadmill n=0). "Kinect Boxing" was the most preferred and the only condition that was physiologically challenging enough to be classified as a

  16. Getting started with Citrix VDI-in-a-Box

    CERN Document Server

    Brown, Stuart Arthur

    2013-01-01

    A practical and fast-paced guide that gives you all the information you need to simplify and streamline virtual desktops so you get a production-quality solution while instantly lowering your costs and improving security.Getting Started with Citrix VDI-in-a-Box is great for IT professionals who are new to VDI-in-a-Box and who are looking for a good grounding in the product. You may be planning to research VDI-in-a-Box in more detail, or you may be tasked with researching how VDI-in-a-Box could improve the productivity of your organization. No prior knowledge of VDI-in-a-Box is required, just a

  17. Integrated Box Interrogation System (IBIS) Preliminary Design Study

    CERN Document Server

    Croft, S; Chard-Mj, P; Estop, J R; Martancik, D; Sheila-Melton; Young, B

    2003-01-01

    Canberra Industries has won the tendered solicitation, INEEL/EST-99-00121 for boxed waste Nondestructive Assay Development and Demonstration. Canberra will provide the Integrated Box Interrogation System (IBIS) which is a suite of assay instrumentation and a data reduction system that addresses the measurement needs for Boxed Wastes identified in the solicitation and facilitates the associated experimental program and demonstration of system capability. The IBIS system will consist of the next generation CWAM system, i.e. CWAM II, which is a Scanning Passive/Active Neutron interrogation system which we will call a Box Segmented Neutron Scanner (BSNS), combined with a physically separate Box Segmented Gamma-ray Scanning (BSGS) system. These systems are based on existing hardware designs but will be tailored to the large sample size and enhanced to allow the program to evaluate the following measurement criteria:Characterization and correction for matrix heterogeneity Characterization of non-uniform radio-nucli...

  18. IEA Common Exercise 4: ARX, ARMAX and grey-box models for thermal performance characterization of the test box

    DEFF Research Database (Denmark)

    Bacher, Peder; Andersen, Philip Hvidthøft Delff

    In this report results of applying time series models for assessing the thermal performance of the IEA Annex 58 test box based on data given in the Common Exercise 4 (CE4), which was measured in Almeria, Spain. Both ARX, ARMAX and grey-box models are applied. Finally, the same models are fitted...

  19. Genome-Wide Organization and Expression Profiling of the SBP-Box Gene Family in Chinese Jujube (Ziziphus jujuba Mill.).

    Science.gov (United States)

    Song, Shuang; Zhou, Heying; Sheng, Songbai; Cao, Ming; Li, Yingyue; Pang, Xiaoming

    2017-08-15

    Transcription factors play vital roles in the developmental processes of plants. The SQUAMOSA promoter binding protein (SBP) genes encode a family of plant-specific transcription factors and plays many crucial roles in plant development. In this study, 16 SBP-box gene family members were identified in Ziziphus jujuba Mill. Dongzao (Dongzao), which were distributed over 8 chromosomes. They were classified into seven groups according to their phylogenetic relationships with other SBP-box gene families. Within each group, genes shared similar exon-intron structures and motif locations. The number of exons varied among the groups. We identified 12 homologous gene pairs between Dongzao and Arabidopsis. Expression profiling revealed that ZjSBP02 and ZjSBP14 expressed highly in mature fruits, ZjSBP01 expressed higher in mature leaves than other tissues and the expression level of ZjSBP12 was much higher in the flowers. The transcriptome analysis indicated that ZjSBPs had different expression patterns in various tissues. This study represents the first systematic analysis of the SBP-box gene family in Z. jujuba. The data presented here provides a foundation for understanding the crucial roles of ZjSBP genes in plant growth and development.

  20. Adaptive evolution in the Arabidopsis MADS-box gene family inferred from its complete resolved phylogeny

    Science.gov (United States)

    Martínez-Castilla, León Patricio; Alvarez-Buylla, Elena R.

    2003-01-01

    Gene duplication is a substrate of evolution. However, the relative importance of positive selection versus relaxation of constraints in the functional divergence of gene copies is still under debate. Plant MADS-box genes encode transcriptional regulators key in various aspects of development and have undergone extensive duplications to form a large family. We recovered 104 MADS sequences from the Arabidopsis genome. Bayesian phylogenetic trees recover type II lineage as a monophyletic group and resolve a branching sequence of monophyletic groups within this lineage. The type I lineage is comprised of several divergent groups. However, contrasting gene structure and patterns of chromosomal distribution between type I and II sequences suggest that they had different evolutionary histories and support the placement of the root of the gene family between these two groups. Site-specific and site-branch analyses of positive Darwinian selection (PDS) suggest that different selection regimes could have affected the evolution of these lineages. We found evidence for PDS along the branch leading to flowering time genes that have a direct impact on plant fitness. Sites with high probabilities of having been under PDS were found in the MADS and K domains, suggesting that these played important roles in the acquisition of novel functions during MADS-box diversification. Detected sites are targets for further experimental analyses. We argue that adaptive changes in MADS-domain protein sequences have been important for their functional divergence, suggesting that changes within coding regions of transcriptional regulators have influenced phenotypic evolution of plants. PMID:14597714

  1. An Arabidopsis F-box protein regulates tapetum degeneration and pollen maturation during anther development.

    Science.gov (United States)

    Kim, Ok-Kyoung; Jung, Jae-Hoon; Park, Chung-Mo

    2010-07-01

    The Arabidopsis anther has a bilateral symmetry with four lobes, each consisting of four distinct layers of somatic cells from the outer to inner side: epidermis, endothecium, middle layer and tapetum. The tapetum is a layer of cells comprising the inner surface of the pollen wall. It plays an important role in anther development by providing enzymes, materials and nutrients required for pollen maturation. Genes and molecular mechanisms underlying tapetum formation and pollen wall biosynthesis have been studied in Arabidopsis. However, tapetum degeneration and anther dehiscence have not been well characterized at the molecular level. Here, we report that an Arabidopsis gene, designated reduced male fertility (RMF), regulates degeneration of tapetum and middle layer during anther development. The Arabidopsis dominant mutant rmf-1D overexpressing the RMF gene exhibited pleiotropic phenotypes, including dwarfed growth with small, dark-green leaves and low male fertility. Tapetum development and subsequent degeneration were impaired in the mutant. Accordingly, pollen maturation was disturbed, reducing the male fertility. In contrast, tapetum degeneration was somewhat accelerated in the RMF RNAi plants. The RMF gene was expressed predominantly in the anther, particularly in the pollen grains. Notably, the RMF protein contains an F-box motif and is localized to the nucleus. It physically interacts with the Arabidopsis-Skp1-like1 protein via the F-box motif. These observations indicate that the RMF gene encodes an F-box protein functioning in tapetum degeneration during anther development.

  2. Characterization and expression analysis of six MADS-box genes in maize (Zea mays L.).

    Science.gov (United States)

    Zhang, Zhongbao; Li, Huiyong; Zhang, Dengfeng; Liu, Yinghui; Fu, Jing; Shi, Yunsu; Song, Yanchun; Wang, Tianyu; Li, Yu

    2012-05-15

    MADS-box genes encode a family of transcription factors, which control diverse developmental processes in flowering plants, with organs ranging from roots, flowers and fruits. In this study, six maize cDNAs encoding MADS-box proteins were isolated. BLASTX searches and phylogenetic analysis indicated that the six MADS-box genes belonging to the AGL2-like clade. qRT-PCR analysis revealed that these genes had differential expression patterns in different organs in maize. The results of yeast one-hybrid system indicated that the protein ZMM3-1, ZMM3-2, ZMM6, ZMM7-L, ZMM8-L and ZMM14-L had transcriptional activation activity. Subcellular localization of ZMM7-L demonstrated that the fluorescence of ZMM7-L-GFP was mainly detected in the nuclei of onion epidermal cells. qRT-PCR analysis for expression pattern of ZMM7-L showed that the gene was up-regulated by abiotic stresses and down-regulated by exogenous ABA. The germination rates of over-expression transgenic lines were lower than that of the wild type on medium with 150 mM NaCl, 350 mM mannitol. These results indicated that ZMM7-L might be a negative transcription factor responsive to abiotic stresses. Copyright © 2012 Elsevier GmbH. All rights reserved.

  3. Estimation parameters and black box model of a brushless DC motor

    Directory of Open Access Journals (Sweden)

    José A. Becerra-Vargas

    2014-08-01

    Full Text Available The modeling of a process or a plant is vital for the design of its control system, since it allows predicting its dynamic and behavior under different circumstances, inputs, disturbances and noise. The main objective of this work is to identify which model is best for a permanent magnet brushless DC specific motor. For this, the mathematical model of a DC motor brushless PW16D, manufactured by Golden Motor, is presented and compared with its black box model; both are derived from experimental data. These data, the average applied voltage and the angular velocity, are acquired by a data acquisition card and imported to the computer. The constants of the mathematical model are estimated by a curve fitting algorithm based on non-linear least squares and pattern search using computational tool. To estimate the mathematical model constants by non-linear least square and search pattern, a goodness of fit of 84.88% and 80.48% respectively was obtained. The goodness of fit obtained by the black box model was 87.72%. The mathematical model presented slightly lower goodness of fit, but allowed to analyze the behavior of variables of interest such as the power consumption and the torque applied to the motor. Because of this, it is concluded that the mathematical model obtained by experimental data of the brushless motor PW16D, is better than its black box model.

  4. Rethinking sanitation: panacea or Pandora's box.

    Science.gov (United States)

    Esrey, S A

    2000-01-01

    In the 19th century, sanitation solutions were designed and built on the premises that human excreta was a waste suitable only for disposal and that the environment was capable of assimilating the waste. The prevailing view last century was that vapors from smells caused disease, and the best way to deal with excreta was to convey it to rivers and streams where it could be diluted and cleansed. Times have changed, the premises are outdated, and current solutions contribute, either directly or indirectly, to many of the problems faced by society today: water pollution, scarcity of fresh water, food insecurity, destruction and loss of soil fertility, loss of biodiversity, depletion of the ozone layer, and global warming. A common denominator of all these problems is how society deals with its wastes, specifically how it deals with human excrement. We have to rethink past premises, design and build new systems, and contribute to the solving of society's most pressing problems. The panacea of the 19th century is turning out to be the pandora's box of the 21st century.

  5. Box Cello Middle School Science Clubs

    Science.gov (United States)

    Vandegrift, Guy

    1998-10-01

    The Box Cello is a middle school science club which is attempting to (1) understand the cello and (2) design a low-cost starter instrument. We can support and justify this research by adding a third goal: (3) to help supply local science classes with equipment. My policy of spending one entire day each week away from the university, out in a local school is essential to this project. This schedule also permits me to conduct lessons on optics and music in the schools. And, it permits circulation of tools and equipment. A simple calculation demonstrates the great economy achieved by combining science clubs with academic year school visits. Consider the cost of letting 10,000 students in 10 middle schools each learn about and play with a pair of "upside-down" glasses for one hour. A visit to each school for three consecutive weeks would easily permit such a circulation if only 30 pairs were constructed. Assume rhetorically, that the construction of 30 pairs of glasses were to consume the entire estimated annual budget of $100,000. The cost per student would be only ten dollars! The visits, guest lectures, and equipment loans permit informal networking (including lunch) with math, science and music teachers in 10 schools. For more information, visit the http://www.utep.edu/boxcello/

  6. Opening up a Colourful Cosmic Jewel Box

    Science.gov (United States)

    2009-10-01

    The combination of images taken by three exceptional telescopes, the ESO Very Large Telescope on Cerro Paranal , the MPG/ESO 2.2-metre telescope at ESO's La Silla observatory and the NASA/ESA Hubble Space Telescope, has allowed the stunning Jewel Box star cluster to be seen in a whole new light. Star clusters are among the most visually alluring and astrophysically fascinating objects in the sky. One of the most spectacular nestles deep in the southern skies near the Southern Cross in the constellation of Crux. The Kappa Crucis Cluster, also known as NGC 4755 or simply the "Jewel Box" is just bright enough to be seen with the unaided eye. It was given its nickname by the English astronomer John Herschel in the 1830s because the striking colour contrasts of its pale blue and orange stars seen through a telescope reminded Herschel of a piece of exotic jewellery. Open clusters [1] such as NGC 4755 typically contain anything from a few to thousands of stars that are loosely bound together by gravity. Because the stars all formed together from the same cloud of gas and dust their ages and chemical makeup are similar, which makes them ideal laboratories for studying how stars evolve. The position of the cluster amongst the rich star fields and dust clouds of the southern Milky Way is shown in the very wide field view generated from the Digitized Sky Survey 2 data. This image also includes one of the stars of the Southern Cross as well as part of the huge dark cloud of the Coal Sack [2]. A new image taken with the Wide Field Imager (WFI) on the MPG/ESO 2.2-metre telescope at ESO's La Silla Observatory in Chile shows the cluster and its rich surroundings in all their multicoloured glory. The large field of view of the WFI shows a vast number of stars. Many are located behind the dusty clouds of the Milky Way and therefore appear red [3]. The FORS1 instrument on the ESO Very Large Telescope (VLT) allows a much closer look at the cluster itself. The telescope's huge mirror

  7. A Grey-Box Dynamic Model of Plate Heat Exchangers Used in an Urban Heating System

    National Research Council Canada - National Science Library

    Qingwei Miao; Shijun You; Wandong Zheng; Xuejing Zheng; Huan Zhang; Yaran Wang

    2017-01-01

    .... In the grey-box method, a newly developed parameter identification method was established. The simulation results of two outlet temperatures by the grey-box and white-box method, respectively, are compared with the test data...

  8. SUPERSTITIOUS BEHAVIOR AMONG JUDO, TAEKWONDO AND BOXING PLAYERS

    Directory of Open Access Journals (Sweden)

    Dureja Gaurav

    2016-04-01

    Full Text Available Purpose: The present study was designed to measure superstitious behavior among Judo, Taekwondo and Boxing players. Material: Thirty (N=30 male inter-college level players with the age group of 19-25 years were selected through purposive sampling technique to act as subjects from affiliated colleges of Panjab University, Chandigarh. They were further divided into three groups: Group-A [Judo (n=10], Group-B [Taekwondo (n=10] and Group-C [Boxing (n=10]. One Way Analysis of Variance (ANOVA was applied to find out the differences among judo, taekwondo and boxing players. Where F values found significant, Least Significant Differences (LSD Post-hoc test was applied to find out the direction and degree of difference. Results: The level of significance was set at 0.05. The result revealed significant differences among judo, taekwondo and boxing players on the sub parameters: clothing and appearance, preparation, team ritual and coach. However, no significant differences have been observed on the sub-parameters fetish, game/competition, prayer and parameter superstitious (Total. Conclusions: The obtained results showed significant differences on the sub-parameter Coach among Judo, Taekwondo and Boxing players. While calculating the mean values of entire groups, it has been observed that Boxing players demonstrate significantly better on the sub-parameter Coach. Therefore, it can be ascertained that Boxing players are more confident that coach bring a lucky charm to our game.

  9. SUPERSTITIOUS BEHAVIOR AMONG JUDO, TAEKWONDO AND BOXING PLAYERS

    Directory of Open Access Journals (Sweden)

    Gaurav Dureja

    2016-04-01

    Full Text Available Purpose: The present study was designed to measure superstitious behavior among Judo, Taekwondo and Boxing players. Material: Thirty (N=30 male inter-college level players with the age group of 19-25 years were selected through purposive sampling technique to act as subjects from affiliated colleges of Panjab University, Chandigarh. They were further divided into three groups: Group-A [Judo (n=10], Group-B [Taekwondo (n=10] and Group-C [Boxing (n=10]. One Way Analysis of Variance (ANOVA was applied to find out the differences among judo, taekwondo and boxing players. Where ‘F’ values found significant, Least Significant Differences (LSD Post-hoc test was applied to find out the direction and degree of difference. Results: The level of significance was set at 0.05. The result revealed significant differences among judo, taekwondo and boxing players on the sub parameters: clothing and appearance, preparation, team ritual and coach. However, no significant differences have been observed on the sub-parameters fetish, game/competition, prayer and parameter superstitious (Total. Conclusions: The obtained results showed significant differences on the sub-parameter Coach among Judo, Taekwondo and Boxing players. While calculating the mean values of entire groups, it has been observed that Boxing players demonstrate significantly better on the sub-parameter Coach. Therefore, it can be ascertained that Boxing players are more confident that coach bring a lucky charm to our game.

  10. Genome-Wide Characterization of the MADS-Box Gene Family in Radish (Raphanus sativusL.) and Assessment of Its Roles in Flowering and Floral Organogenesis.

    Science.gov (United States)

    Li, Chao; Wang, Yan; Xu, Liang; Nie, Shanshan; Chen, Yinglong; Liang, Dongyi; Sun, Xiaochuan; Karanja, Benard K; Luo, Xiaobo; Liu, Liwang

    2016-01-01

    The MADS-box gene family is an important transcription factor (TF) family that is involved in various aspects of plant growth and development, especially flowering time and floral organogenesis. Although it has been reported in many plant species, the systematic identification and characterization of MADS-box TF family is still limited in radish ( Raphanus sativus L.). In the present study, a comprehensive analysis of MADS-box genes was performed, and a total of 144 MADS-box family members were identified from the whole radish genome. Meanwhile, a detailed list of MADS-box genes from other 28 plant species was also investigated. Through the phylogenetic analysis between radish and Arabidopsis thaliana , all the RsMADS genes were classified into two groups including 68 type I (31 Mα, 12 Mβ and 25Mγ) and 76 type II (70 MIKC C and 6 MIKC ∗ ). Among them, 41 (28.47%) RsMADS genes were located in nine linkage groups of radish from R1 to R9. Moreover, the homologous MADS-box gene pairs were identified among radish, A. thaliana , Chinese cabbage and rice. Additionally, the expression profiles of RsMADS genes were systematically investigated in different tissues and growth stages. Furthermore, quantitative real-time PCR analysis was employed to validate expression patterns of some crucial RsMADS genes. These results could provide a valuable resource to explore the potential functions of RsMADS genes in radish, and facilitate dissecting MADS-box gene-mediated molecular mechanisms underlying flowering and floral organogenesis in root vegetable crops.

  11. Genome-wide characterization of the MADS-box gene family in radish (Raphanus sativus L. and assessment of its roles in flowering and floral organogenesis

    Directory of Open Access Journals (Sweden)

    Chao Li

    2016-09-01

    Full Text Available The MADS-box gene family is an important transcription factor (TF family that is involved in various aspects of plant growth and development, especially flowering time and floral organogenesis. Although it has been reported in many plant species, the systematic identification and characterization of MADS-box TF family is still limited in radish (Raphanus sativus L.. In the present study, a comprehensive analysis of MADS-box genes was performed, and a total of 144 MADS-box family members were identified from the whole radish genome. Meanwhile, a detailed list of MADS-box genes from other 28 plant species was also investigated. Through the phylogenetic analysis between radish and Arabidopsis thaliana, all the RsMADS genes were classified into two groups including 68 type I (31 Mα, 12 Mβ and 25Mγ and 76 type II (70 MIKCC and 6 MIKC*. Among them, 41 (28.47% RsMADS genes were located in nine linkage groups of radish from R1 to R9. Moreover, the homologous MADS-box gene pairs were identified among radish, A. thaliana, Chinese cabbage and rice. Additionally, the expression profiles of RsMADS genes were systematically investigated in different tissues and growth stages. Furthermore, quantitative real-time PCR analysis was employed to validate expression patterns of some crucial RsMADS genes. These results could provide a valuable resource to explore the potential functions of RsMADS genes in radish, and facilitate dissecting MADS-box gene-mediated molecular mechanisms underlying flowering and floral organogenesis in root vegetable crops.

  12. Security of the AES with a Secret S-Box

    DEFF Research Database (Denmark)

    Tiessen, Tyge; Knudsen, Lars Ramkilde; Kölbl, Stefan

    2015-01-01

    How does the security of the AES change when the S-box is replaced by a secret S-box, about which the adversary has no knowledge? Would it be safe to reduce the number of encryption rounds? In this paper, we demonstrate attacks based on integral cryptanalysis which allow to recover both the secret...... key and the secret S-box for respectively four, five, and six rounds of the AES. Despite the significantly larger amount of secret information which an adversary needs to recover, the attacks are very efficient with time/data complexities of 217/216, 238/240 and 290/264, respectively. Another...

  13. Utilization of Boxes for Pesticide Storage in Sri Lanka

    DEFF Research Database (Denmark)

    Pieris, Ravi; Weerasinghe, Manjula; Abeywickrama, Tharaka

    2017-01-01

    Pesticide self-poisoning is now considered one of the two most common methods of suicide worldwide. Encouraging safe storage of pesticides is one particular approach aimed at reducing pesticide self-poisoning. CropLife Sri Lanka (the local association of pesticide manufacturers), with the aid...... of the Department of Agriculture, distributed lockable in-house pesticide storage boxes free of charge to a farming community in a rural district of Sri Lanka. Padlocks were not provided with the boxes. These storage boxes were distributed to the farmers without prior education. The authors carried out a cross...

  14. Quartic Box-Spline Reconstruction on the BCC Lattice.

    Science.gov (United States)

    Kim, Minho

    2013-02-01

    This paper presents an alternative box-spline filter for the body-centered cubic (BCC) lattice, the seven-direction quartic box-spline M7 that has the same approximation order as the eight-direction quintic box-spline M8 but a lower polynomial degree, smaller support, and is computationally more efficient. When applied to reconstruction with quasi-interpolation prefilters, M7 shows less aliasing, which is verified quantitatively by integral filter metrics and frequency error kernels. To visualize and analyze distributional aliasing characteristics, each spectrum is evaluated on the planes and lines with various orientations.

  15. Trial manufacture of portable type `WISH BOX`; Kahangata WISH BOX no shisaku kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Ushiyama, I.; Sakuma, H.; Qin, W. [Ashikaga Institute of Technology, Tochigi (Japan); Onai, Y.

    1996-10-27

    This paper proposes the small portable type power source `WISH BOX` (wind and solar hybrid) composed of a small wind power generator and solar cell panels. Since solar radiation and wind power are complementary to each other in seasons, day and night, and fine and cloudy weather, WISH BOX is useful for standalone power source in non-power areas of developing countries, life spot in disasters, and outdoor leisure. The most small light-weight high-performance AIR303 produced by Southwest Windpower Co., USA is used as wind power generator, and two 50W solar cell panels HSC-5010-S produced by Daido Hokusan Co. is used. Sealed lead storage batteries (12V, 20Ah each) are also connected to cope with load fluctuation. In comparison with conventional portable gasoline engine generators, this environment-friendly generator is featured by fuel-free, no emission of gases, no noises and no fire occurrence, and can also supply stable power with small batteries even in the nighttime and cloudy weather by combining wind power. The generator of 400,000 yen is now in field experiment. 2 refs., 5 figs.

  16. bHLH106 Integrates Functions of Multiple Genes through Their G-Box to Confer Salt Tolerance on Arabidopsis.

    Directory of Open Access Journals (Sweden)

    Aftab Ahmad

    Full Text Available An activation-tagging methodology was applied to dedifferentiated calli of Arabidopsis to identify new genes involved in salt tolerance. This identified salt tolerant callus 8 (stc8 as a gene encoding the basic helix-loop-helix transcription factor bHLH106. bHLH106-knockout (KO lines were more sensitive to NaCl, KCl, LiCl, ABA, and low temperatures than the wild-type. Back-transformation of the KO line rescued its phenotype, and over-expression (OX of bHLH106 in differentiated plants exhibited tolerance to NaCl. Green fluorescent protein (GFP fused with bHLH106 revealed that it was localized to the nucleus. Prepared bHLH106 protein was subjected to electrophoresis mobility shift assays against E-box sequences (5'-CANNTG-3'. The G-box sequence 5'-CACGTG-3' had the strongest interaction with bHLH106. bHLH106-OX lines were transcriptomically analyzed, and resultant up- and down-regulated genes selected on the criterion of presence of a G-box sequence. There were 198 genes positively regulated by bHLH106 and 36 genes negatively regulated; these genes possessed one or more G-box sequences in their promoter regions. Many of these genes are known to be involved in abiotic stress response. It is concluded that bHLH106 locates at a branching point in the abiotic stress response network by interacting directly to the G-box in genes conferring salt tolerance on plants.

  17. 47 CFR 90.241 - Radio call box operations.

    Science.gov (United States)

    2010-10-01

    ... transmitter can be only manually reactivated. (9) Frequency selection must be made with regard to reception of... effective radiated power (ERP). (3) The height of a call box antenna may not exceed 6.1 meters (20 feet...

  18. FDA boxed warnings: how to prescribe drugs safely.

    Science.gov (United States)

    O'Connor, Nina R

    2010-02-01

    Boxed warnings, commonly referred to as "black box" warnings, are issued by the U.S. Food and Drug Administration and featured in the labeling of drugs associated with serious adverse reactions. These safety concerns are typically identified through the Adverse Event Reporting System and the Office of Surveillance and Epidemiology, which evaluates postmarket safety findings. The most common type of warning is issued when there is a potentially serious adverse effect that must be carefully weighed against the potential benefit of the drug. Warnings are also issued to draw attention to dosing, monitoring requirements, and potential drug interactions. Boxed warnings have been issued recently for oral sodium phosphate bowel preparations, fluoroquinolone antibiotics, and salmeterol. Despite these highly publicized warnings, all of these medications remain viable treatment options with appropriate patient selection. Ultimately, physicians must decide whether to prescribe drugs with boxed warnings. Copyright (c) 2010 American Academy of Family Physicians.

  19. T-Box Genes in Human Development and Disease.

    Science.gov (United States)

    Ghosh, T K; Brook, J D; Wilsdon, A

    2017-01-01

    T-box genes are important development regulators in vertebrates with specific patterns of expression and precise roles during embryogenesis. They encode transcription factors that regulate gene transcription, often in the early stages of development. The hallmark of this family of proteins is the presence of a conserved DNA binding motif, the "T-domain." Mutations in T-box genes can cause developmental disorders in humans, mostly due to functional deficiency of the relevant proteins. Recent studies have also highlighted the role of some T-box genes in cancer and in cardiomyopathy, extending their role in human disease. In this review, we focus on ten T-box genes with a special emphasis on their roles in human disease. © 2017 Elsevier Inc. All rights reserved.

  20. Cryogenic distribution box for Fermi National Accelerator Laboratory

    Science.gov (United States)

    Svehla, M. R.; Bonnema, E. C.; Cunningham, E. K.

    2017-12-01

    Meyer Tool & Mfg., Inc (Meyer Tool) of Oak Lawn, Illinois is manufacturing a cryogenic distribution box for Fermi National Accelerator Laboratory (FNAL). The distribution box will be used for the Muon-to-electron conversion (Mu2e) experiment. The box includes twenty-seven cryogenic valves, two heat exchangers, a thermal shield, and an internal nitrogen separator vessel, all contained within a six-foot diameter ASME coded vacuum vessel. This paper discusses the design and manufacturing processes that were implemented to meet the unique fabrication requirements of this distribution box. Design and manufacturing features discussed include: 1) Thermal strap design and fabrication, 2) Evolution of piping connections to heat exchangers, 3) Nitrogen phase separator design, 4) ASME code design of vacuum vessel, and 5) Cryogenic valve installation.

  1. Generalized box-plot for root growth ensembles

    National Research Council Canada - National Science Library

    Vad, Viktor; Cedrim, Douglas; Busch, Wolfgang; Filzmoser, Peter; Viola, Ivan

    2017-01-01

    .... We use the generalized box plot concept with a new formulation of data depth. In addition to spatial distributions, we created a visual representation to encode temporal distributions associated with the development of root individuals...

  2. Injury and injury rates in Muay Thai kick boxing

    National Research Council Canada - National Science Library

    Gartland, S; Malik, M H; Lovell, M E

    2001-01-01

    To determine the type and number of injuries that occur during the training and practice of Muay Thai kick boxing and to compare the data obtained with those from previous studies of karate and taekwondo...

  3. Box photosynthesis modeling results for WRF/CMAQ LSM

    Data.gov (United States)

    U.S. Environmental Protection Agency — Box Photosynthesis model simulations for latent heat and ozone at 6 different FLUXNET sites. This dataset is associated with the following publication: Ran, L., J....

  4. EPA EcoBox Tools by Stressors - Physical

    Science.gov (United States)

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  5. EPA EcoBox Tools by Stressors - Stressors in ERA

    Science.gov (United States)

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  6. EPA EcoBox Tools by Stressors - Chemical

    Science.gov (United States)

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  7. EPA EcoBox Tools by Stressors - Biological

    Science.gov (United States)

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  8. Venom proteome of the box jellyfish Chironex fleckeri

    National Research Council Canada - National Science Library

    Brinkman, Diane L; Aziz, Ammar; Loukas, Alex; Potriquet, Jeremy; Seymour, Jamie; Mulvenna, Jason

    2012-01-01

    .... The box jellyfish, Chironex fleckeri, produces exceptionally potent and rapid-acting venom and its stings to humans cause severe localized and systemic effects that are potentially life-threatening...

  9. Design and development of a freezer and chiller delivery box

    Science.gov (United States)

    Zakaria, Mohd Zakimi; Hung, Goh Chung; Dawi, Mohd Syedi Imran Mohd; Hussin, Radhwan; Khalil, Ahmad Nabil Mohd; Naim, Muhammad Khairy Md; Hilmi, Ahmad Humaizi

    2017-09-01

    This paper presents an action research of designed and fabricated using well insulating materials in order to ensure the coolness inside the freezer and chiller delivery box is as good minimize temperature raised. The main purpose of this study is to develop freeze and chiller delivery box that will be able to keep fresh meat during travelling long delivery. A range of freeze and chill solutions exists for that must be kept within a specific temperature range throughout the supply-and-distribution chain. This will help to minimize the activeness of bacteria to spoil the meats, at the same time it can linger the duration for meats to spoil. All affecting parameter such as temperature inside the delivery box, heat transfer rate, and natural convection flow pattern has been studied to design and development of the delivery box. Finally, temperature distribution analysis has been conducted which showed that in operating condition inside temperature are suitable to keep the fresh meats condition.

  10. Reflective Cracking between Precast Prestressed Box Girders : Research Brief

    Science.gov (United States)

    2017-08-01

    Ease of construction, favorable span-to-depth ratios, aesthetic appeal and high torsional stiffness make adjacent precast prestressed concrete box-beams a popular option for short-to-medium span bridges. However, persisting durability and performance...

  11. Matter-wave dark solitons in box-like traps

    CERN Document Server

    Sciacca, M; Parker, N G

    2016-01-01

    Motivated by the experimental development of quasi-homogeneous Bose-Einstein condensates confined in box-like traps, we study numerically the dynamics of dark solitons in such traps at zero temperature. We consider the cases where the side walls of the box potential rise either as a power-law or a Gaussian. While the soliton propagates through the homogeneous interior of the box without dissipation, it typically dissipates energy during a reflection from a wall through the emission of sound waves, causing a slight increase in the soliton's speed. We characterise this energy loss as a function of the wall parameters. Moreover, over multiple oscillations and reflections in the box-like trap, the energy loss and speed increase of the soliton can be significant, although the decay eventually becomes stabilized when the soliton equilibrates with the ambient sound field.

  12. Injury and injury rates in Muay Thai kick boxing

    OpenAIRE

    Gartland, S; Malik, M; Lovell, M.

    2001-01-01

    Objective—To determine the type and number of injuries that occur during the training and practice of Muay Thai kick boxing and to compare the data obtained with those from previous studies of karate and taekwondo.

  13. EPA EcoBox Tools by Exposure Pathways - Food Chains

    Science.gov (United States)

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  14. Overlap Areas of a Square Box on a Square Mesh

    Science.gov (United States)

    2017-04-01

    ARL-TN-0818 ● APR 2017 US Army Research Laboratory Overlap Areas of a Square Box on a Square Mesh by James U Cazamias...originator. ARL-TN-0818 ● APR 2017 US Army Research Laboratory Overlap Areas of a Square Box on a Square Mesh by James U Cazamias...no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control

  15. The DEAD-box helicase eIF4A

    Science.gov (United States)

    Andreou, Alexandra Z.; Klostermeier, Dagmar

    2013-01-01

    DEAD-box helicases catalyze the ATP-dependent unwinding of RNA duplexes. They share a helicase core formed by two RecA-like domains that carries a set of conserved motifs contributing to ATP binding and hydrolysis, RNA binding and duplex unwinding. The translation initiation factor eIF4A is the founding member of the DEAD-box protein family, and one of the few examples of DEAD-box proteins that consist of a helicase core only. It is an RNA-stimulated ATPase and a non-processive helicase that unwinds short RNA duplexes. In the catalytic cycle, a series of conformational changes couples the nucleotide cycle to RNA unwinding. eIF4A has been considered a paradigm for DEAD-box proteins, and studies of its function have revealed the governing principles underlying the DEAD-box helicase mechanism. However, as an isolated helicase core, eIF4A is rather the exception, not the rule. Most helicase modules in other DEAD-box proteins are modified, some by insertions into the RecA-like domains, and the majority by N- and C-terminal appendages. While the basic catalytic function resides within the helicase core, its modulation by insertions, additional domains or a network of interaction partners generates the diversity of DEAD-box protein functions in the cell. This review summarizes the current knowledge on eIF4A and its regulation, and discusses to what extent eIF4A serves as a model DEAD-box protein. PMID:22995829

  16. Safety evaluation for packaging (onsite) depleted uranium waste boxes

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, W.A.

    1997-08-27

    This safety evaluation for packaging (SEP) allows the one-time shipment of ten metal boxes and one wooden box containing depleted uranium material from the Fast Flux Test Facility to the burial grounds in the 200 West Area for disposal. This SEP provides the analyses and operational controls necessary to demonstrate that the shipment will be safe for the onsite worker and the public.

  17. Oriented Spatial Box Plot, a New Pattern for Points Clusters

    OpenAIRE

    Etienne, Laurent; Devogele, Thomas; McArdle, Gavin

    2014-01-01

    Nowadays, an abundance of sensors are used to collect very large datasets containing spatial points which can be mined and analyzed to extract meaningful patterns and information. This article examines patterns which describe the dispersion of 2D data around a central tendency. Several state of the art patterns for point cluster analysis are presented and critiqued before a new pattern, the Oriented Spatial Box Plot, is defined. The Oriented Spatial Box Plot extends the clas...

  18. A pharmacological and biochemical characterisation of Australian box jellyfish venoms

    OpenAIRE

    Winter, Kelly Lee

    2017-01-01

    Box jellyfish are found throughout the northern tropical waters of Australia and are responsible for considerable morbidity and mortality. Chironex fleckeri is arguably the most venomous creature in the world and has been responsible for over 70 deaths. Despite considerable research, the mechanisms of action of these venoms have yet to be elucidated. The current study investigated the pharmacological and biochemical characteristics of venom from the following species of box jellyfish: C. flec...

  19. Coupling polariton quantum boxes in sub-wavelength grating microcavities

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Bo; Wang, Zhaorong; Deng, Hui, E-mail: dengh@umich.edu [Department of Physics, University of Michigan, Ann Arbor, Michigan 48109 (United States); Brodbeck, Sebastian; Kamp, Martin; Schneider, Christian [Technische Physik, Physikalisches Institut and Wilhelm Conrad Röntgen-Research Center for Complex Material Systems, Universität Würzburg, Am Hubland, D-97074 Würzburg (Germany); Höfling, Sven [Technische Physik, Physikalisches Institut and Wilhelm Conrad Röntgen-Research Center for Complex Material Systems, Universität Würzburg, Am Hubland, D-97074 Würzburg (Germany); SUPA, School of Physics and Astronomy, University of St Andrews, St Andrews KY16 9SS (United Kingdom)

    2015-02-02

    We report the construction of decoupled, coupled, and quasi-one dimensional polariton systems from zero dimensional polariton quantum boxes using microcavities with sub-wavelength gratings as the top mirror. By designing the tethering patterns around the suspended sub-wavelength gratings, we control the coupling between individual quantum boxes through different optical potentials. Energy levels and real-space or momentum space distributions of the confined modes were measured, which agreed well with simulations.

  20. Gray-box modelling approach for description of storage tunnel

    DEFF Research Database (Denmark)

    Harremoës, Poul; Carstensen, Jacob

    1999-01-01

    The dynamics of a storage tunnel is examined using a model based on on-line measured data and a combination of simple deterministic and black-box stochastic elements. This approach, called gray-box modeling, is a new promising methodology for giving an on-line state description of sewer systems. ...... in a SCADA system because the most important information on the specific system is provided on-line...

  1. SF Box--a tool for evaluating the effects on soil functions in remediation projects.

    Science.gov (United States)

    Volchko, Yevheniya; Norrman, Jenny; Rosén, Lars; Norberg, Tommy

    2014-10-01

    Although remediation is usually aimed at reducing the risks posed by contaminants to human health and the environment, it is also desirable that the remediated soil within future green spaces is capable of providing relevant ecological functions, e.g., basis for primary production. Yet while addressing a contamination problem by reducing contaminant concentration and/or amounts in the soil, the remedial action itself can lead to soil structure disturbances, decline in organic matter and nutrient deficiencies, and in turn affect a soil's capacity to carry out its ecological soil functions. This article presents the Soil Function Box (SF Box) tool that is aimed to facilitate integration of information from suggested soil quality indicators (SQIs) into a management process in remediation using a scoring method. The scored SQIs are integrated into a soil quality index corresponding to 1 of 5 classes. SF Box is applied to 2 cases from Sweden (Kvillebäcken and Hexion), explicitly taking into consideration uncertainties in the results by means of Monte Carlo simulations. At both sites the generated soil quality indices corresponded to a medium soil performance (soil class 3) with a high certainty. The main soil constraints at both Kvillebäcken and Hexion were associated with biological activity in the soil, as soil organisms were unable to supply plant-available N. At the Kvillebäcken site the top layer had a content of coarse fragment (ø > 2 mm) higher than 35%, indicating plant rooting limitations. At the Hexion site, the soil had limited amount of organic matter, thus poor aggregate stability and nutrient cycling potential. In contrast, the soil at Kvillebäcken was rich in organic matter. The soils at both sites were capable of storing a sufficient amount of water for soil organisms between precipitation events. © 2014 SETAC.

  2. Striking dynamics and kinetic properties of boxing and MMA gloves

    Directory of Open Access Journals (Sweden)

    Benjamin Lee

    2014-08-01

    Full Text Available With the growing popularity of Mixed Martial Arts (MMA as a competitive sport, questions regarding the dynamic response and properties of MMA gloves arise. High-energy impacts from punches are very similar to boxing yet MMA competition requires the use of 4 oz fingerless glove, compared to the larger full enclosure boxing glove. This work assessed the kinetic properties and strike dynamics of MMA gloves and compared findings with traditional boxing gloves. Gloves mounted on a molded fist were impacted repetitively on an instrumental anvil designed for impact, over a 5 hour period resulting in 10,000 continuous and consistent strikes. Kinetic data from impacts were sampled at the beginning of the data collection and subsequently every 30 minutes (every 1,000 strikes. MMA gloves produced 4-5 times greater peak force and 5 times faster load rate compared to the boxing glove. However, MMA gloves also showed signs of material fatigue, with peak force increasing by 35% and rate of loading increasing by 60% over the duration of the test. Boxing glove characteristics did deteriorate but to a lesser extent. In summary, the kinetic properties of MMA glove differed substantially from the boxing glove resulting in impacts characterized by higher peak forces and more rapid development of force. Material properties including stiffness and thickness play a role in the kinetic characteristics upon impact, and can be inferred to alter injury mechanisms of blunt force trauma.

  3. RNAa Induced by TATA Box-Targeting MicroRNAs.

    Science.gov (United States)

    Zhang, Yijun; Zhang, Hui

    2017-01-01

    Recent studies reveal that some nuclear microRNAs (miRNA) and synthesized siRNAs target gene promoters to activate gene transcription (RNAa). Interestingly, our group identified a novel HIV-1-encoded miRNA, miR-H3, which targets specifically the core promoter TATA box of HIV-1 and activates viral gene expression. Depletion of miR-H3 significantly impaired the replication of HIV-1. miR-H3 mimics could activate viruses from CD4(+) T cells isolated from patients receiving suppressive highly active antiretroviral therapy, which is very intriguing for reducing HIV-1 latent reservoir. Further study revealed that many cellular miRNAs also function like miR-H3. For instance, let-7i targets the TATA box of the interleukin-2 (IL-2) promoter and upregulates IL-2 expression in T-lymphocytes. In RNAa induced by TATA box-targeting miRNAs, Argonaute (AGO) proteins are needed, but there is no evidence for the involvement of promoter-associated transcripts or epigenetic modifications. We propose that the binding of small RNA-AGO complex to TATA box could facilitate the assembly of RNA Polymerase II transcription preinitiation complex. In addition, synthesized small RNAs targeting TATA box can also efficiently activate transcription of interested genes, such as insulin, IL-2, and c-Myc. The discovery of RNAa induced by TATA box-targeting miRNA provides an easy-to-use tool for activating gene expression.

  4. Unconventional Bearing Capacity Analysis and Optimization of Multicell Box Girders

    Directory of Open Access Journals (Sweden)

    Jovan Tepic

    2014-01-01

    Full Text Available This study deals with unconventional bearing capacity analysis and the procedure of optimizing a two-cell box girder. The generalized model which enables the local stress-strain analysis of multicell girders was developed based on the principle of cross-sectional decomposition. The applied methodology is verified using the experimental data (Djelosevic et al., 2012 for traditionally formed box girders. The qualitative and quantitative evaluation of results obtained for the two-cell box girder is realized based on comparative analysis using the finite element method (FEM and the ANSYS v12 software. The deflection function obtained by analytical and numerical methods was found consistent provided that the maximum deviation does not exceed 4%. Multicell box girders are rationally designed support structures characterized by much lower susceptibility of their cross-sectional elements to buckling and higher specific capacity than traditionally formed box girders. The developed local stress model is applied for optimizing the cross section of a two-cell box carrier. The author points to the advantages of implementing the model of local stresses in the optimization process and concludes that the technological reserve of bearing capacity amounts to 20% at the same girder weight and constant load conditions.

  5. Identification and quantification of expression levels of three FRUITFULL-like MADS-box genes from the orchid Dendrobium thyrsiflorum (Reichb. f.)

    DEFF Research Database (Denmark)

    Skipper, Martin; Pedersen, Kim B.; Johansen, Louise Buchholt

    2005-01-01

    Orchids serve as useful model plants for the discovery and study of genes involved in novel processes in floral development because of their highly modified flowers. In this study three different FRUITFULL (FUL)-like MADS-box genes, DthyrFL1, -2, and -3 have been isolated from the orchid Dendrobium...

  6. Characterization and expression analysis of AGAMOUS-like, SEEDSTICK-like, and SEPALLATA-like MADS-box genes in peach (Prunus persica) fruit.

    Science.gov (United States)

    Tani, Eleni; Polidoros, Alexios N; Flemetakis, Emmanouil; Stedel, Catalina; Kalloniati, Chrissanthi; Demetriou, Kyproula; Katinakis, Panagiotis; Tsaftaris, Athanasios S

    2009-08-01

    MADS-box genes encode transcriptional regulators that are critical for flowering, flower organogenesis and plant development. Although there are extensive reports on genes involved in flower organogenesis in model and economically important plant species, there are few reports on MADS-box genes in woody plants. In this study, we have cloned and characterized AGAMOUS (AG), SEEDSTICK (STK) and SEPALLATA (SEP) homologs from peach tree (Prunus persica L. Batsch) and studied their expression patterns in different tissues as well as in fruit pericarp during pit hardening. AG- STK- and SEP-like homologs, representative of the C-, D-, E-like MADS-box gene lineages, respectively, play key roles in stamen, carpel, ovule and fruit development in Arabidopsis thaliana. Sequence similarities, phylogenetic analysis and structural characteristics were used to provide classification of the isolated genes in type C (PPERAG), type D (PPERSTK) and type E (PPERSEP1, PPERSEP3, PPERFB9) organ identity genes. Expression patterns were determined and in combination with phylogenetic data provided useful indications on the function of these genes. These data suggest the involvement of MADS-box genes in peach flower and fruit development and provide further evidence for the role of these genes in woody perennial trees that is compatible with their function in model plant species.

  7. Meal box schemes a convenient way to avoid convenience food? Uses and understandings of meal box schemes among Danish consumers.

    Science.gov (United States)

    Hertz, Frej Daniel; Halkier, Bente

    2017-07-01

    The term convenience food is subject to diversification, lack of clarity and moral ambiguity. In this paper we address these issues and critically discuss convenience food by using empirical findings from a Danish study that deals with practitioners' uses of meal box schemes. The methodological design consists of thirteen individual interviews, four focus groups and some observations of cooking practices. We combine the empirical findings with a particular definition of convenience food by Brunner et al. (2010) and selected practice theoretical concepts. This particular combination enables us to categorize meal box schemes as a new form of convenience food called convenient food. In addition, results suggest that meal box schemes reduce leftovers from dinner. Meal boxes also influence dinner related activities such as planning ahead in time and grocery shopping, which require less physical and mental effort. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Neural and Neural Gray-Box Modeling for Entry Temperature Prediction in a Hot Strip Mill

    Science.gov (United States)

    Barrios, José Angel; Torres-Alvarado, Miguel; Cavazos, Alberto; Leduc, Luis

    2011-10-01

    In hot strip mills, initial controller set points have to be calculated before the steel bar enters the mill. Calculations rely on the good knowledge of rolling variables. Measurements are available only after the bar has entered the mill, and therefore they have to be estimated. Estimation of process variables, particularly that of temperature, is of crucial importance for the bar front section to fulfill quality requirements, and the same must be performed in the shortest possible time to preserve heat. Currently, temperature estimation is performed by physical modeling; however, it is highly affected by measurement uncertainties, variations in the incoming bar conditions, and final product changes. In order to overcome these problems, artificial intelligence techniques such as artificial neural networks and fuzzy logic have been proposed. In this article, neural network-based systems, including neural-based Gray-Box models, are applied to estimate scale breaker entry temperature, given its importance, and their performance is compared to that of the physical model used in plant. Several neural systems and several neural-based Gray-Box models are designed and tested with real data. Taking advantage of the flexibility of neural networks for input incorporation, several factors which are believed to have influence on the process are also tested. The systems proposed in this study were proven to have better performance indexes and hence better prediction capabilities than the physical models currently used in plant.

  9. "Light-box" accelerated growth of poinsettias: LED-only illumination

    Science.gov (United States)

    Weerasuriya, Charitha; Detez, Stewart; Hock Ng, Soon; Hughes, Andrew; Callaway, Michael; Harrison, Iain; Katkus, Tomas; Juodkazis, Saulius

    2018-01-01

    For the current commercialized agricultural industry which requires a reduced product lead time to customer and supply all year round, an artificial light emitting diodes (LEDs)-based illumination has high potential due to high efficiency of electrical-to-light conversion. The main advantage of the deployed Red Green Blue Amber LED lighting system is colour mixing capability, which means ability to generate all the colours in the spectrum by using three or four primary colours LEDs. The accelerated plant growth was carried out in a "light-box" which was made to generate an artificial day/night cycle by moving the colour mixing ratio along the colour temperature curve of the chromaticity diagram. The control group of plants form the same initial batch was grown on the same shelf in a greenhouse at the same conditions with addition of artificial illumination by incandescent lamps for few hours. Costs and efficiency projections of LED lamps for horticultural applications is discussed together with required capital investment. The total cost of the "light-box" including LED lamps and electronics was 850 AUD.

  10. Comparative Human and Automatic Evaluation of Glass-Box and Black-Box Approaches to Interactive Translation Prediction

    OpenAIRE

    Torregrosa Daniel; Pérez-Ortiz Juan Antonio; Forcada Mikel L.

    2017-01-01

    Interactive translation prediction (ITP) is a modality of computer-aided translation that assists professional translators by offering context-based computer-generated continuation suggestions as they type. While most state-of-the-art ITP systems follow a glass-box approach, meaning that they are tightly coupled to an adapted machine translation system, a black-box approach which does not need access to the inner workings of the bilingual resources used to generate the suggestions has been re...

  11. Comparative Human and Automatic Evaluation of Glass-Box and Black-Box Approaches to Interactive Translation Prediction

    Directory of Open Access Journals (Sweden)

    Torregrosa Daniel

    2017-06-01

    Full Text Available Interactive translation prediction (ITP is a modality of computer-aided translation that assists professional translators by offering context-based computer-generated continuation suggestions as they type. While most state-of-the-art ITP systems follow a glass-box approach, meaning that they are tightly coupled to an adapted machine translation system, a black-box approach which does not need access to the inner workings of the bilingual resources used to generate the suggestions has been recently proposed in the literature: this new approach allows new sources of bilingual information to be included almost seamlessly. In this paper, we compare for the first time the glass-box and the black-box approaches by means of an automatic evaluation of translation tasks between related languages such as English–Spanish and unrelated ones such as Arabic–English and English–Chinese, showing that, with our setup, 20%–50% of keystrokes could be saved using either method and that the black-box approach outperformed the glass-box one in five out of six scenarios operating under similar conditions. We also performed a preliminary human evaluation of English to Spanish translation for both approaches. On average, the evaluators saved 10% keystrokes and were 4% faster with the black-box approach, and saved 15% keystrokes and were 12% slower with the glass-box one; but they could have saved 51% and 69% keystrokes respectively if they had used all the compatible suggestions. Users felt the suggestions helped them to translate faster and easier. All the tools used to perform the evaluation are available as free/open–source software.

  12. Analysis of MADS-Box Gene Family Reveals Conservation in Floral Organ ABCDE Model of Moso Bamboo (Phyllostachys edulis

    Directory of Open Access Journals (Sweden)

    Zhanchao Cheng

    2017-05-01

    Full Text Available Mini chromosome maintenance 1, agamous, deficiens, and serum response factor (MADS-box genes are transcription factors which play fundamental roles in flower development and regulation of floral organ identity. However, till date, identification and functions of MADS-box genes remain largely unclear in Phyllostachys edulis. In view of this, we performed a whole-genome survey and identified 34 MADS-box genes in P. edulis, and based on phylogeny, they were classified as MIKCC, MIKC∗, Mα, and Mβ. The detailed analysis about gene structure and motifs, phylogenetic classification, comparison of gene divergence and duplication are provided. Interestingly, expression patterns for most genes were found similar to those of Arabidopsis and rice, indicating that the well-established ABCDE model can be applied to P. edulis. Moreover, we overexpressed PheMADS15, an AP1-like gene, in Arabidopsis, and found that the transgenic plants have early flowering phenotype, suggesting that PheMADS15 might be a regulator of flowering transition in P. edulis. Taken together, this study provides not only insightful comprehension but also useful information for understanding the functions of MADS-box genes in P. edulis.

  13. An anther development F-box (ADF) protein regulated by tapetum degeneration retardation (TDR) controls rice anther development.

    Science.gov (United States)

    Li, Li; Li, Yixing; Song, Shufeng; Deng, Huafeng; Li, Na; Fu, Xiqin; Chen, Guanghui; Yuan, Longping

    2015-01-01

    In this study, we reported that a F-box protein, OsADF, as one of the direct targets of TDR , plays a critical role in rice tapetum cell development and pollen formation. The tapetum, the innermost sporophytic tissue of anther, plays an important supportive role in male reproduction in flowering plants. After meiosis, tapetal cells undergo programmed cell death (PCD) and provide nutrients for pollen development. Previously we showed that tapetum degeneration retardation (TDR), a basic helix-loop-helix transcription factor, can trigger tapetal PCD and control pollen wall development during anther development. However, the comprehensive regulatory network of TDR remains to be investigated. In this study, we cloned and characterized a panicle-specific expression F-box protein, anther development F-box (OsADF). By qRT-PCR and RNA in situ hybridization, we further confirmed that OsADF expressed specially in tapetal cells from stage 9 to stage 12 during anther development. In consistent with this specific expression pattern, the RNAi transgenic lines of OsADF exhibited abnormal tapetal degeneration and aborted microspores development, which eventually grew pollens with reduced fertility. Furthermore, we demonstrated that the TDR, a key regulator in controlling rice anther development, could regulate directly the expression of OsADF by binding to E-box motifs of its promoter. Therefore, this work highlighted the possible regulatory role of TDR, which regulates tapetal cell development and pollen formation via triggering the possible ADF-mediated proteolysis pathway.

  14. Influence of dimension box differences and time differences during operations of red box for motorcycles at signalized intersection

    Science.gov (United States)

    Mulyadi, Agah Muhammad

    2017-11-01

    Performance of signalized intersection has declined due to a large number of motorcycles. The number of motorcycles reached 98.2 million units and the composition of motorcycles has reached around 81.7% of the total composition of vehicles in Indonesia (AISI, 2017). To solve that problem, the red box for motorcycles are provided at the signalized intersection. Red box for the motorcycle at signalized intersections was developed from the concept of Advance Stop Line (ASL) for bicycles. The Red Box was developed to split the queue between motorcycles and other vehicles when waiting at red light. This paper aims to evaluate the influence of the red box dimension and red time operation differences. The survey was conducted as many as 30 cycles of traffic signals per day. The data were analyzed using software IBM SPSS Statistics 20 by using Analysis of Variance (ANOVA) to obtain p-value (significant). The analysis shows that there are insignificant influences between the occupancy rates to the dimension of Red Box. Furthermore, that there is a significant difference that shows the dependency of only motorcycles in the Red Box Area towards red time operation.

  15. Natural and induced loss of function mutations in SlMBP21 MADS-box gene led to jointless-2 phenotype in tomato

    OpenAIRE

    Gomez Roldan, Maria Victoria; Périlleux, Claire; Morin, Halima; Huerga Fernandez, Samuel; Latrasse, David; Benhamed, Moussa; Bendahmane, Abdelhafid

    2017-01-01

    Abscission is the mechanism by which plants disconnect unfertilized flowers, ripe fruits, senescent or diseased organs from the plant. In tomato, pedicel abscission is an important agronomic factor that controls yield and post-harvest fruit quality. Two non-allelic mutations, jointless (j) and jointless-2 (j-2), controlling pedicel abscission zone formation have been documented but only j-2 has been extensively used in breeding. J was shown to encode a MADS-box protein. Using a combination of...

  16. 76 FR 54931 - Post Office (PO) Box Fee Groups for Merged Locations

    Science.gov (United States)

    2011-09-06

    ... 111 Post Office (PO) Box Fee Groups for Merged Locations AGENCY: Postal Service TM . ACTION: Final..., Domestic Mail Manual (DMM ) 508.4 to allow Post Office Box TM (PO Box TM ) fee groups to be merged due to... lower, and only once per calendar year. Absent this change, where a box section is merged with a...

  17. Autoantibodies Against High Mobility Group Box 1 (HMGB1) in Patients with SLE

    NARCIS (Netherlands)

    Schaper, Fleur; Horst, Gerda; Henegouwen, Daan van Beijeren Bergenen; Bijzet, Johan; de Leeuw, Karina; Stel, Alja; Limburg, Pieter C.; Heeringa, Peter; Westra, Johanna

    2014-01-01

    Background/Purpose: High mobility group box 1 (HMGB1) is a damage-associated molecular pattern and can be divided in three separate domains: the A Box, B Box and the acidic tail. Box A by itself serves as a competitive antagonist for HMGB1 and inhibits HMGB1 activity. In an earlier study we showed

  18. Box-trees and R-trees with near-optimal query time

    NARCIS (Netherlands)

    Agarwal, P.K.; Berg, M. de; Gudmundsson, J.; Hammar, M.; Haverkort, H.J.

    2001-01-01

    A box-tree is a bounding-volume hierarchy that uses axis-aligned boxes as bounding volumes. The query complexity of a box-tree with respect to a given type of query is the maximum number of nodes visited when answering such a query. We describe several new algorithms for constructing box-trees

  19. Total Radiosynthesis: Thinking outside "the box".

    Science.gov (United States)

    Liang, Steven H; Vasdev, Neil

    2015-09-01

    The logic of total synthesis transformed a stagnant state of medicinal and synthetic organic chemistry when there was a paucity of methods and reagents to synthesize drug molecules and/or natural products. Molecular imaging by positron emission tomography (PET) is now experiencing a renaissance in the way radiopharmaceuticals for molecular imaging are synthesized, however, a paradigm shift is desperately needed in the discovery pipeline to accelerate in vivo imaging studies. A significant challenge in radiochemistry is the limited choice of labeled reagents (or building blocks) available for the synthesis of novel radiopharmaceuticals with the most commonly used short-lived radionuclides carbon-11 (11C; half-life ~20 minutes) and fluorine-18 (18F; half-life ~2 hours). In fact, most drugs cannot be labeled with 11C or 18F due to a lack of efficient and diverse radiosynthetic methods. In general, routine radiopharmaceutical production relies on the incorporation of the isotope at the last or penultimate step of synthesis, ideally within one half-life of the radionuclide, to maximize radiochemical yields and specific activities thereby reducing losses due to radioactive decay. Reliance on radiochemistry conducted within the constraints of an automated synthesis unit ("box") has stifled the exploration of multi-step reactions with short-lived radionuclides. Radiopharmaceutical synthesis can be transformed by considering logic of total synthesis to develop novel approaches for 11C- and 18F-radiolabeling complex molecules via retrosynthetic analysis and multi-step reactions. As a result of such exploration, new methods, reagents and radiopharmaceuticals for in vivo imaging studies are discovered. A new avenue to develop radiotracers that were previously unattainable due to the lack of efficient radiosynthetic methods is necessary to work towards our ultimate, albeit impossible goal - the concept we term total radiosynthesis - to radiolabel virtually any molecule. As with

  20. A novel method to design S-box based on chaotic map and genetic algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yong, E-mail: wangyong_cqupt@163.com [State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University, Chongqing 400044 (China); Key Laboratory of Electronic Commerce and Logistics, Chongqing University of Posts and Telecommunications, Chongqing 400065 (China); Wong, Kwok-Wo [Department of Electronic Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong (Hong Kong); Li, Changbing [Key Laboratory of Electronic Commerce and Logistics, Chongqing University of Posts and Telecommunications, Chongqing 400065 (China); Li, Yang [Department of Automatic Control and Systems Engineering, The University of Sheffield, Mapping Street, S1 3DJ (United Kingdom)

    2012-01-30

    The substitution box (S-box) is an important component in block encryption algorithms. In this Letter, the problem of constructing S-box is transformed to a Traveling Salesman Problem and a method for designing S-box based on chaos and genetic algorithm is proposed. Since the proposed method makes full use of the traits of chaotic map and evolution process, stronger S-box is obtained. The results of performance test show that the presented S-box has good cryptographic properties, which justify that the proposed algorithm is effective in generating strong S-boxes. -- Highlights: ► The problem of constructing S-box is transformed to a Traveling Salesman Problem. ► We present a new method for designing S-box based on chaos and genetic algorithm. ► The proposed algorithm is effective in generating strong S-boxes.

  1. Integrated Box Interrogation System (IBIS) Preliminary Design Study

    Energy Technology Data Exchange (ETDEWEB)

    DR. Stephen Croft; Mr. David Martancik; Dr. Brian Young; Dr. Patrick MJ Chard; Dr. Robert J Estop; Sheila Melton; Gaetano J. Arnone

    2003-01-13

    Canberra Industries has won the tendered solicitation, INEEL/EST-99-00121 for boxed waste Nondestructive Assay Development and Demonstration. Canberra will provide the Integrated Box Interrogation System (IBIS) which is a suite of assay instrumentation and a data reduction system that addresses the measurement needs for Boxed Wastes identified in the solicitation and facilitates the associated experimental program and demonstration of system capability. The IBIS system will consist of the next generation CWAM system, i.e. CWAM II, which is a Scanning Passive/Active Neutron interrogation system which we will call a Box Segmented Neutron Scanner (BSNS), combined with a physically separate Box Segmented Gamma-ray Scanning (BSGS) system. These systems are based on existing hardware designs but will be tailored to the large sample size and enhanced to allow the program to evaluate the following measurement criteria:Characterization and correction for matrix heterogeneity Characterization of non-uniform radio-nuclide and isotopic compositions Assay of high density matrices (both high-Z and high moderator contents)Correction for radioactive material physical form - such as self shielding or multiplication effects due to large accumulations of radioactive materials.Calibration with a minimal set of reference standards and representative matrices.THis document summarizes the conceptual design parameters of the IBIS and indicates areas key to the success of the project where development is to be centered. The work presented here is a collaborative effort between scientific staff within Canberra and within the NIS-6 group at LANL.

  2. Computational Fluid Dynamics Analysis of Flexible Duct Junction Box Design

    Energy Technology Data Exchange (ETDEWEB)

    Beach, Robert [IBACOS Inc., Pittsburgh, PA (United States); Prahl, Duncan [IBACOS Inc., Pittsburgh, PA (United States); Lange, Rich [IBACOS Inc., Pittsburgh, PA (United States)

    2013-12-01

    IBACOS explored the relationships between pressure and physical configurations of flexible duct junction boxes by using computational fluid dynamics (CFD) simulations to predict individual box parameters and total system pressure, thereby ensuring improved HVAC performance. Current Air Conditioning Contractors of America (ACCA) guidance (Group 11, Appendix 3, ACCA Manual D, Rutkowski 2009) allows for unconstrained variation in the number of takeoffs, box sizes, and takeoff locations. The only variables currently used in selecting an equivalent length (EL) are velocity of air in the duct and friction rate, given the first takeoff is located at least twice its diameter away from the inlet. This condition does not account for other factors impacting pressure loss across these types of fittings. For each simulation, the IBACOS team converted pressure loss within a box to an EL to compare variation in ACCA Manual D guidance to the simulated variation. IBACOS chose cases to represent flows reasonably correlating to flows typically encountered in the field and analyzed differences in total pressure due to increases in number and location of takeoffs, box dimensions, and velocity of air, and whether an entrance fitting is included. The team also calculated additional balancing losses for all cases due to discrepancies between intended outlet flows and natural flow splits created by the fitting. In certain asymmetrical cases, the balancing losses were significantly higher than symmetrical cases where the natural splits were close to the targets. Thus, IBACOS has shown additional design constraints that can ensure better system performance.

  3. Laparoscopic virtual reality simulator and box trainer in gynecology.

    Science.gov (United States)

    Akdemir, Ali; Sendağ, Fatih; Oztekin, Mehmet K

    2014-05-01

    To investigate whether a virtual reality simulator (LapSim) and traditional box trainer are effective tools for the acquisition of basic laparoscopic skills, and whether the LapSim is superior to the box trainer in surgical education. In a study at Ege University School of Medicine, Izmir, Turkey, between September 2008 and March 2013, 40 first- and second-year residents were randomized to train via the LapSim or box trainer for 4 weeks, and 20 senior residents were allocated to a control group. All 3 groups performed laparoscopic bilateral tubal ligation. Video records of each operation were assessed via the general rating scale of the Objective Structured Assessment of Laparoscopic Salpingectomy and by operation time in seconds. Compared with the control group, the LapSim and box trainer groups performed significantly better in total score (Peducation. Training with a virtual reality simulator or box trainer should be considered before actual laparoscopic procedures are carried out. Copyright © 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  4. Motivation of students to boxing during physical education

    Directory of Open Access Journals (Sweden)

    Nazymok V.V.

    2012-09-01

    Full Text Available Showing survey results of students I - II courses about issues of motivation for boxing in physical education. The survey involved 100 students. Among them, 88 men and 12 women. It is established that the majority of respondents did not engage in boxing before entering the university. The main motives for classes in boxing are improving physical fitness and self-confidence. Fears of boxing cause poor physical and moral - psychological preparation, the fear to miss bounce or be injured. It is shown that the box in the technical university engaged in 5.5%, 2.8% of the fight and taekwondo 2.1% of students. Absolute leaders are athletic gymnastics and swimming 13.7% 13.3%. Also popular team sports football 8.7%, 5.5% of basketball, volleyball, 5.3%. Unfortunately, the number of students that attend due to health and exercise therapy SMG also has a fairly substantial 6.3%. Enough to visit among girls is 6.1% aerobics and shaping of 5.8.

  5. DEAD-box proteins as RNA helicases and chaperones

    Science.gov (United States)

    Jarmoskaite, Inga; Russell, Rick

    2010-01-01

    DEAD-box proteins are ubiquitous in RNA-mediated processes and function by coupling cycles of ATP binding and hydrolysis to changes in affinity for single-stranded RNA. Many DEAD-box proteins use this basic mechanism as the foundation for a version of RNA helicase activity, efficiently separating the strands of short RNA duplexes in a process that involves little or no translocation. This activity, coupled with mechanisms to direct different DEAD-box proteins to their physiological substrates, allows them to promote RNA folding steps and rearrangements and to accelerate remodeling of RNA-protein complexes. This review will describe the properties of DEAD-box proteins as RNA helicases and the current understanding of how the energy from ATPase activity is used to drive the separation of RNA duplex strands. It will then describe how the basic biochemical properties allow some DEAD-box proteins to function as chaperones by promoting RNA folding reactions, with a focus on the self-splicing group I and group II intron RNAs. PMID:21297876

  6. T-Box Genes in the Kidney and Urinary Tract.

    Science.gov (United States)

    Kispert, A

    2017-01-01

    T-box (Tbx) genes encode an ancient group of transcription factors that play important roles in patterning, specification, proliferation, and differentiation programs in vertebrate organogenesis. This is testified by severe organ malformation syndromes in mice homozygous for engineered null alleles of specific T-box genes and by the large number of human inherited organ-specific diseases that have been linked to mutations in these genes. One of the organ systems that has not been associated with loss of specific T-box gene function in human disease for long is the excretory system. However, this has changed with the finding that mutations in TBX18, a member of a vertebrate-specific subgroup within the Tbx1-subfamily of T-box transcription factor genes, cause congenital anomalies of the kidney and urinary tract, predominantly hydroureter and ureteropelvic junction obstruction. Gene expression analyses, loss-of-function studies, and lineage tracing in the mouse suggest a primary role for this transcription factor in specifying the ureteric mesenchyme in the common anlage of the kidney, the ureter, and the bladder. We review the function of Tbx18 in ureterogenesis and discuss the body of evidence that Tbx18 and other members of the T-box gene family, namely, Tbx1, Tbx2, Tbx3, and Tbx20, play additional roles in development and homeostasis of other components of the excretory system in vertebrates. © 2017 Elsevier Inc. All rights reserved.

  7. Creep behavior of precast segmental box girder bridge

    Science.gov (United States)

    Xihua, Dai; Liangfang, Liu; Rong, Xian

    2017-08-01

    The concrete creep effect is more obvious when the box girder is assembled by segment. It is necessary to consider the influence of the loading value of the section at different time and the different age of concrete at different stages. In this paper, ACI209R-92, CEB-FIP MC90 and B3 and other concrete creep models are compared. The results show that the B3 model has many factors to consider and the calculation accuracy is high. Secondly, this paper discusses the influence of the segmental construction technology on the creep calculation, and puts forward the characteristics of the stress analysis of the segmental box girder. Finally, on the basis of the B3 model of concrete creep, the Midas software is used to establish the calculation model of segmental box girder, and the internal force and deformation of the box girder are calculated. The results show that the internal force and deformation of the box girder is too large due to the poor integrity of the segmental assembling process, which will seriously affect the normal service performance.

  8. The extra-depth toe box: a rational approach.

    Science.gov (United States)

    Kaye, R A

    1994-03-01

    The conservative management of foot deformities often requires the use of a modified shoe. A higher toe box is one of the most common variations required when the abnormality is located in region of the forefoot. High toe boxes are available in a variety of footgear, including athletic sneakers, comfort shoes, and prescription footwear. A rational approach to accommodating a deformed forefoot would be to first measure the maximum height of the abnormal toes in a weightbearing position. Then, by referring to a table listing shoes and available toe box space, the physician could match the foot with a shoe. The purpose of this study was to collect and tabulate measurements of toe box height for a variety of shoes. Impressions were taken from various shoes using a moldable plastic material. Toe box height was then measured and recorded. Results were tabulated for various types of men's and women's shoes. The depth of shoes at the point 5 cm from the tip of the toe was about 44 mm for most styles. The sagittal profile (i.e., vertical height available) of extra-depth shoes, comfort shoes, and athletic shoes was similar.

  9. Using a box instead of a column for process chromatography.

    Science.gov (United States)

    Ghosh, Raja

    2016-10-14

    Columns with relatively short bed-height to diameter ratios are frequently used for process-scale chromatography applications such as biopharmaceutical purification. Non-uniform flow distribution within such columns could result in broad and poorly resolved eluted peaks, which could in turn affect purity, recovery and productivity of the process. Different strategies centered on improved column header design have been proposed for addressing this problem. This paper describes a radically different approach, i.e. the use of a chromatography box (or chromato-box) instead of a column, for addressing the challenges posed by flow mal-distribution in process-scale, packed-bed chromatography devices. The design of the chromatography box devices used in this study is based on a laterally-fed membrane chromatography (or LFMC) device, that has been described and discussed in several recent papers. The performances of two chromatography box devices were compared with their equivalent columns in terms of sharpness and asymmetry of flow-through and eluted peaks, number of theoretical plates per metre, and peak resolution in binary and ternary protein separations. In each of the above comparisons, the chromatography box devices performed better than their equivalent columns, clearly indicating their potential as an alternative in process-scale chromatography applications. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Boxes and Sound Quality in AN Italian Opera House

    Science.gov (United States)

    COCCHI, A.; GARAI, M.; TAVERNELLI, C.

    2000-04-01

    The “Teatro Comunale” (City Theatre) in Bologna is an Italian opera house of the 18th century, designed by the famous architect Antonio Galli Bibiena. Largely built in masonry, it has been only partially restored and altered several times, but never destroyed and rebuilt. The study of its acoustics, while interesting for itself, offers the opportunity to investigate the role of the boxes, which constitute the most evident characteristic of Italian opera houses. The study was carried on at first by measurements, acquiring binaural impulse responses in the stalls and in the boxes, and then by computer simulation, modelling also some changes which cannot be done in the real hall. The measurements revealed clear differences between the listening quality in the boxes and in the stalls, especially regarding ITDG, clarity and IACC. Computer simulations show how the sound field in the historical theatre could be if the sound absorption of the boxes were changed, adding some velvet curtains, as was done in ancient times, and clarify the effects of the cavities which constitutes the boxes.

  11. A photo-responsive F-box protein FOF2 regulates floral initiation by promoting FLC expression in Arabidopsis.

    Science.gov (United States)

    He, Reqing; Li, Xinmei; Zhong, Ming; Yan, Jindong; Ji, Ronghuan; Li, Xu; Wang, Qin; Wu, Dan; Sun, Mengsi; Tang, Dongying; Lin, Jianzhong; Li, Hongyu; Liu, Bin; Liu, Hongtao; Liu, Xuanming; Zhao, Xiaoying; Lin, Chentao

    2017-09-01

    Floral initiation is regulated by various genetic pathways in response to light, temperature, hormones and developmental status; however, the molecular mechanisms underlying the interactions between different genetic pathways are not fully understood. Here, we show that the photoresponsive gene FOF2 (F-box of flowering 2) negatively regulates flowering. FOF2 encodes a putative F-box protein that interacts specifically with ASK14, and its overexpression results in later flowering under both long-day and short-day photoperiods. Conversely, transgenic plants expressing the F-box domain deletion mutant of FOF2 (FOF2ΔF), or double loss of function mutant of FOF2 and FOL1 (FOF2-LIKE 1) present early flowering phenotypes. The late flowering phenotype of the FOF2 overexpression lines is suppressed by the flc-3 loss-of-function mutation. Furthermore, FOF2 mRNA expression is regulated by autonomous pathway gene FCA, and the repressive effect of FOF2 in flowering can be overcome by vernalization. Interestingly, FOF2 expression is regulated by light. The protein level of FOF2 accumulates in response to light, whereas it is degraded under dark conditions via the 26S proteasome pathway. Our findings suggest a possible mechanistic link between light conditions and the autonomous floral promotion pathway in Arabidopsis. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

  12. Cannabis: A Treasure Trove or Pandora's Box?

    Science.gov (United States)

    Solymosi, Katalin; Köfalvi, Attila

    2017-01-01

    Cannabis is one of the earliest cultivated plants. Cannabis of industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is bred for medical, spiritual and recreational purposes is called marijuana. The female marijuana plant produces a significant quantity of bio- and psychoactive phytocannabinoids, which regained the spotlight with the discovery of the endocannabinoid system of the animals in the early 90's. Nevertheless, marijuana is surrounded by controversies, debates and misconceptions related to its taxonomic classification, forensic identification, medical potential, legalization and its long-term health consequences. In the first part, we provide an in-depth review of the botany and taxonomy of Cannabis. We then overview the biosynthesis of phytocannabinoids within the glandular trichomes with emphasis on the role of peculiar plastids in the production of the secreted material. We also compile the analytical methods used to determine the phytocannabinoid composition of glandular trichomes. In the second part, we revisit the psychobiology and molecular medicine of marijuana. We summarize our current knowledge on the recreational use of cannabis with respect to the modes of consumption, short-term effects, chronic health consequences and cannabis use disorder. Next, we overview the molecular targets of a dozen major and minor bioactive cannabinoids in the body. This helps us introduce the endocannabinoid system in an unprecedented detail: its up-todate molecular biology, pharmacology, physiology and medical significance, and beyond. In conclusion, we offer an unbiased survey about cannabis to help better weigh its medical value versus the associated risks. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  13. Flora, life form and chorology of Box trees (Buxus hyrcana habitats in forests of the Farim area of Sari

    Directory of Open Access Journals (Sweden)

    Seyedeh Samira Soleymanipour

    2015-07-01

    Full Text Available This study intends to present floristic-physiognomic investigation of Box trees (Buxus hyrcana of the Farim area of Sari. All of species in the area were recorded by two methods field-walk and 60 releves with an area of 400 m2 in a systematic-selective design in two elevation classes, more and less than 1200 m above sea level implemented. Our results showed that the flora of this region includes 47 families, 67 genera, and 77 species. Phanerophytes (37.7%, Cryptophytes (32.5% and Hemicryptophytes (24.7% were the most important structure groups of the local biological spectrum according to Raunkiaer method, and also with increasing elevation, portions of Hemicryptophytes and Cryptophytes increased and decreased, respectively. Chorological studies showed that chorotype form Euro-Sibria was the most important phytochorion in two habitats. The correlation of environment variables with two first axes of DCA showed that elevation of sea level and dominance average (canopy percentage of Box trees had decisive role on the vegetation composition and mean richness of species (Hill N0 index. Also, Jackknife estimation results confirmed that species richness in habitats with elevation more than 1200 m (75.8 species had a higher level compared to habitats with elevation less than 1200 m (58.6 species because of decreasing box trees dominance. Totally, the results of the present study not only confirmed the ecological capacity of Box trees in developing up to 1700 m in mountain forests of north Iran, but also the association of box trees with some plants of high regions with steep slope of north Hyrcanian forests such as: Acer mazandaranicum, Carpinus schuschaensis and Taxus baccata, can be introduced as two new syntaxa including Taxus baccata- Buxus hyrcana and Carpinus schuschaensis- Buxus hyrcana in Hyrcanian forests.

  14. Immunohistochemical evidence for multiple photosystems in box jellyfish

    DEFF Research Database (Denmark)

    Ekström, Peter; Garm, Anders Lydik; Pålsson, Jonas

    2008-01-01

    data demonstrate that the lens eyes of box jellyfish utilize a single opsin and are thus color-blind, and that there is probably a different photopigment in the pigment cup eyes. The results support our hypothesis that the lens eyes and the pigment cup eyes of box jellyfish are involved in different......Cubomedusae (box jellyfish) possess a remarkable visual system with 24 eyes distributed in four sensory structures termed rhopalia. Each rhopalium is equipped with six eyes: two pairs of pigment cup eyes and two unpaired lens eyes. Each eye type probably captures specific features of the visual...... environment. To investigate whether multiple types of photoreceptor cells are present in the rhopalium, and whether the different eye types possess different types of photoreceptors, we have used immunohistochemistry with a range of vertebrate opsin antibodies to label the photoreceptors...

  15. Ber analysis of the box relaxation for BPSK signal recovery

    KAUST Repository

    Thrampoulidis, Christos

    2016-06-24

    We study the problem of recovering an n-dimensional BPSK signal from m linear noise-corrupted measurements using the box relaxation method which relaxes the discrete set {±1}n to the convex set [-1,1]n to obtain a convex optimization algorithm followed by hard thresholding. When the noise and measurement matrix have iid standard normal entries, we obtain an exact expression for the bit-wise probability of error Pe in the limit of n and m growing and m/n fixed. At high SNR our result shows that the Pe of box relaxation is within 3dB of the matched filter bound (MFB) for square systems, and that it approaches the (MFB) as m grows large compared to n. Our results also indicate that as m, n → ∞, for any fixed set of size k, the error events of the corresponding k bits in the box relaxation method are independent.

  16. BOX-COX REGRESSION METHOD IN TIME SCALING

    Directory of Open Access Journals (Sweden)

    ATİLLA GÖKTAŞ

    2013-06-01

    Full Text Available Box-Cox regression method with λj, for j = 1, 2, ..., k, power transformation can be used when dependent variable and error term of the linear regression model do not satisfy the continuity and normality assumptions. The situation obtaining the smallest mean square error  when optimum power λj, transformation for j = 1, 2, ..., k, of Y has been discussed. Box-Cox regression method is especially appropriate to adjust existence skewness or heteroscedasticity of error terms for a nonlinear functional relationship between dependent and explanatory variables. In this study, the advantage and disadvantage use of Box-Cox regression method have been discussed in differentiation and differantial analysis of time scale concept.

  17. Track plate enclosures: Box designs affecting attractiveness to riparian mammals

    Science.gov (United States)

    Loukmas, J.J.; Mayack, D.T.; Richmond, M.E.

    2003-01-01

    We examined the efficacy of four track plate enclosure designs for monitoring the abundance of small and medium-sized mammals along 10 streams in New York State. Box size and clarity of view through the box were evaluated as factors affecting visitation. We checked track plate stations weekly from September 1999 to March 2000. Eleven mammalian species or species groups visited the track plate stations. Raccoons (Procyon lotor) (P = 0.020) and feral cats (Felis catus) (P = 0.008) visited large enclosures significantly more than small enclosures. Feral cats visited clear-view enclosures significantly more than obstructed-view enclosures (P = 0.025). Enclosure size and view did not significantly affect visitation by other species; however, a large box with a clear view was the most effective design.

  18. The SRY gene HMG-box in micro- and megabats.

    Science.gov (United States)

    Bullejos, M; Sánchez, A; Burgos, M; Jiménez, R; Díaz De La Guardia, R

    2000-01-01

    Sex determination in mammals is controlled by the Y-linked SRY gene, which encodes a transcription factor with a DNA-binding motif of the HMG type. The only conserved region in this gene is the HMG-box, whose nucleotide sequence is currently available in a number of mammalian taxa. However, nothing is known about this gene in bats. Here, we report partial sequences of the SRY HMG-box from four microbat and four megabat species. We used the SRY HMG- box sequences from micro- and megabats to test the phylogenetic relationships between microbats, megabats, and primates. In maximum parsimony and maximum-likelihood trees, mega- and microbat branches start in the same internal node, which is consistent with a monophyletic origin of this mammalian group. Copyright 2000 S. Karger AG, Basel

  19. A Finite Segment Method for Skewed Box Girder Analysis

    Directory of Open Access Journals (Sweden)

    Xingwei Xue

    2018-01-01

    Full Text Available A finite segment method is presented to analyze the mechanical behavior of skewed box girders. By modeling the top and bottom plates of the segments with skew plate beam element under an inclined coordinate system and the webs with normal plate beam element, a spatial elastic displacement model for skewed box girder is constructed, which can satisfy the compatibility condition at the corners of the cross section for box girders. The formulation of the finite segment is developed based on the variational principle. The major advantage of the proposed approach, in comparison with the finite element method, is that it can simplify a three-dimensional structure into a one-dimensional structure for structural analysis, which results in significant saving in computational times. At last, the accuracy and efficiency of the proposed finite segment method are verified by a model test.

  20. Optimatization of loop heat pipe for cooling of electrotechnical box

    Science.gov (United States)

    Roman, Banovcan; Tomas, Puchor; Andrej, Kapjor; Milan, Malcho

    2017-09-01

    The paper deals with use of LOOP thermosyphon heat pipe to transfer heat from electrotechnical box and describe of construction individual types of LOOP heat pipes. The LOOP heat pipe is very good cooling device which requires no mechanical parts in their design. LOOP heat pipe use only phase change during heat transfer, without a compressor, fan or pump. LOOP heat pipe is more energy saving compared to conventional cooling systems with forced convection. The main advantage of cooling by heat pipe is that electrotechnical box can be hermetically closed (dust -free construction), because dust reduces the lifetime of electrotechnical elements in box. Lifetime of LOOP heat pipe equals to the lifetime of construction material. The paper describes mathematical model of LOOP thermosyphon heat pipe (condenser). Compares selected types of working fluids which are filled with a heat pipe and construction materials of heat pipe.

  1. Surface reflectance drives nest box temperature profiles and thermal suitability for target wildlife.

    Directory of Open Access Journals (Sweden)

    Stephen R Griffiths

    Full Text Available Thermal properties of tree hollows play a major role in survival and reproduction of hollow-dependent fauna. Artificial hollows (nest boxes are increasingly being used to supplement the loss of natural hollows; however, the factors that drive nest box thermal profiles have received surprisingly little attention. We investigated how differences in surface reflectance influenced temperature profiles of nest boxes painted three different colors (dark-green, light-green, and white: total solar reflectance 5.9%, 64.4%, and 90.3% respectively using boxes designed for three groups of mammals: insectivorous bats, marsupial gliders and brushtail possums. Across the three different box designs, dark-green (low reflectance boxes experienced the highest average and maximum daytime temperatures, had the greatest magnitude of variation in daytime temperatures within the box, and were consistently substantially warmer than light-green boxes (medium reflectance, white boxes (high reflectance, and ambient air temperatures. Results from biophysical model simulations demonstrated that variation in diurnal temperature profiles generated by painting boxes either high or low reflectance colors could have significant ecophysiological consequences for animals occupying boxes, with animals in dark-green boxes at high risk of acute heat-stress and dehydration during extreme heat events. Conversely in cold weather, our modelling indicated that there are higher cumulative energy costs for mammals, particularly smaller animals, occupying light-green boxes. Given their widespread use as a conservation tool, we suggest that before boxes are installed, consideration should be given to the effect of color on nest box temperature profiles, and the resultant thermal suitability of boxes for wildlife, particularly during extremes in weather. Managers of nest box programs should consider using several different colors and installing boxes across a range of both orientations and

  2. Surface reflectance drives nest box temperature profiles and thermal suitability for target wildlife.

    Science.gov (United States)

    Griffiths, Stephen R; Rowland, Jessica A; Briscoe, Natalie J; Lentini, Pia E; Handasyde, Kathrine A; Lumsden, Linda F; Robert, Kylie A

    2017-01-01

    Thermal properties of tree hollows play a major role in survival and reproduction of hollow-dependent fauna. Artificial hollows (nest boxes) are increasingly being used to supplement the loss of natural hollows; however, the factors that drive nest box thermal profiles have received surprisingly little attention. We investigated how differences in surface reflectance influenced temperature profiles of nest boxes painted three different colors (dark-green, light-green, and white: total solar reflectance 5.9%, 64.4%, and 90.3% respectively) using boxes designed for three groups of mammals: insectivorous bats, marsupial gliders and brushtail possums. Across the three different box designs, dark-green (low reflectance) boxes experienced the highest average and maximum daytime temperatures, had the greatest magnitude of variation in daytime temperatures within the box, and were consistently substantially warmer than light-green boxes (medium reflectance), white boxes (high reflectance), and ambient air temperatures. Results from biophysical model simulations demonstrated that variation in diurnal temperature profiles generated by painting boxes either high or low reflectance colors could have significant ecophysiological consequences for animals occupying boxes, with animals in dark-green boxes at high risk of acute heat-stress and dehydration during extreme heat events. Conversely in cold weather, our modelling indicated that there are higher cumulative energy costs for mammals, particularly smaller animals, occupying light-green boxes. Given their widespread use as a conservation tool, we suggest that before boxes are installed, consideration should be given to the effect of color on nest box temperature profiles, and the resultant thermal suitability of boxes for wildlife, particularly during extremes in weather. Managers of nest box programs should consider using several different colors and installing boxes across a range of both orientations and shade profiles (i

  3. Surface reflectance drives nest box temperature profiles and thermal suitability for target wildlife

    Science.gov (United States)

    Rowland, Jessica A.; Briscoe, Natalie J.; Lentini, Pia E.; Handasyde, Kathrine A.; Lumsden, Linda F.; Robert, Kylie A.

    2017-01-01

    Thermal properties of tree hollows play a major role in survival and reproduction of hollow-dependent fauna. Artificial hollows (nest boxes) are increasingly being used to supplement the loss of natural hollows; however, the factors that drive nest box thermal profiles have received surprisingly little attention. We investigated how differences in surface reflectance influenced temperature profiles of nest boxes painted three different colors (dark-green, light-green, and white: total solar reflectance 5.9%, 64.4%, and 90.3% respectively) using boxes designed for three groups of mammals: insectivorous bats, marsupial gliders and brushtail possums. Across the three different box designs, dark-green (low reflectance) boxes experienced the highest average and maximum daytime temperatures, had the greatest magnitude of variation in daytime temperatures within the box, and were consistently substantially warmer than light-green boxes (medium reflectance), white boxes (high reflectance), and ambient air temperatures. Results from biophysical model simulations demonstrated that variation in diurnal temperature profiles generated by painting boxes either high or low reflectance colors could have significant ecophysiological consequences for animals occupying boxes, with animals in dark-green boxes at high risk of acute heat-stress and dehydration during extreme heat events. Conversely in cold weather, our modelling indicated that there are higher cumulative energy costs for mammals, particularly smaller animals, occupying light-green boxes. Given their widespread use as a conservation tool, we suggest that before boxes are installed, consideration should be given to the effect of color on nest box temperature profiles, and the resultant thermal suitability of boxes for wildlife, particularly during extremes in weather. Managers of nest box programs should consider using several different colors and installing boxes across a range of both orientations and shade profiles (i

  4. Divergence of recently duplicated M{gamma}-type MADS-box genes in Petunia.

    Science.gov (United States)

    Bemer, Marian; Gordon, Jonathan; Weterings, Koen; Angenent, Gerco C

    2010-02-01

    The MADS-box transcription factor family has expanded considerably in plants via gene and genome duplications and can be subdivided into type I and MIKC-type genes. The two gene classes show a different evolutionary history. Whereas the MIKC-type genes originated during ancient genome duplications, as well as during more recent events, the type I loci appear to experience high turnover with many recent duplications. This different mode of origin also suggests a different fate for the type I duplicates, which are thought to have a higher chance to become silenced or lost from the genome. To get more insight into the evolution of the type I MADS-box genes, we isolated nine type I genes from Petunia, which belong to the Mgamma subclass, and investigated the divergence of their coding and regulatory regions. The isolated genes could be subdivided into two categories: two genes were highly similar to Arabidopsis Mgamma-type genes, whereas the other seven genes showed less similarity to Arabidopsis genes and originated more recently. Two of the recently duplicated genes were found to contain deleterious mutations in their coding regions, and expression analysis revealed that a third paralog was silenced by mutations in its regulatory region. However, in addition to the three genes that were subjected to nonfunctionalization, we also found evidence for neofunctionalization of one of the Petunia Mgamma-type genes. Our study shows a rapid divergence of recently duplicated Mgamma-type MADS-box genes and suggests that redundancy among type I paralogs may be less common than expected.

  5. Effects of thermal insulation on electrical connections and outlet boxes

    Science.gov (United States)

    Beausoliel, R. W.; Clifton, J. R.; Meese, W. J.

    1981-04-01

    When residential walls are retrofitted with foamed-in urea formaldehyde or blown-in cellulose thermal insulations, the insulation may enter electrical outlet and switch boxes. The effects of these thermal insulations on the durability of electrical components were studied. These studies were carried out at 44, 75, and 96 percent relative humidities with test periods between one and twelve months. Laboratory test methods were developed and tests performed to determine the electrical and corrosive effects of urea formaldehyde and cellulose thermal insulation contained in electrical outlet and switch boxes.

  6. Analysis of white box test of cyber-physical system

    Science.gov (United States)

    Li, Bo; Zhang, Lichen

    2017-05-01

    The Cyber-Physical System is a complex system in which the information system is closely integrated with the physical system. Through the environment detection and the combination of computing, communication and control process, the physical real-time perception and dynamic control function are realized. CPS is another information revolution after the Internet, and his presence will change the way people interact with the physical world. In this paper, the concept of CPS and white box testing is introduced, and then the white box test for CPS hardware, software, network and system is discussed in detail. Finally, the research on CPS is prospected.

  7. Box jellyfish use terrestrial visual cues for navigation

    DEFF Research Database (Denmark)

    Garm, Anders; Oskarsson, Magnus; Nilsson, Dan-Eric

    2011-01-01

    Box jellyfish have an impressive set of 24 eyes of four different types, including eyes structurally similar to those of vertebrates and cephalopods [1, 2]. However, the known visual responses are restricted to simple phototaxis, shadow responses, and object avoidance responses [3-8], and it has...... been a puzzle why they need such a complex set of eyes. Here we report that medusae of the box jellyfish Tripedalia cystophora are capable of visually guided navigation in mangrove swamps using terrestrial structures seen through the water surface. They detect the mangrove canopy by an eye type...

  8. Low-profile self-sealing sample transfer flexure box.

    Science.gov (United States)

    Simon, Kevin; Porz, Lukas; Swamy, Tushar; Chiang, Yet-Ming; Slocum, Alexander

    2017-08-01

    A flexural bearing mechanism has enabled the development of a self-sealing box for protecting air sensitive samples during transfer between glove boxes, micro-machining equipment, and microscopy equipment. The simplicity and self-actuating feature of this design makes it applicable to many devices that operate under vacuum conditions. The models used to design the flexural mechanism are presented in detail. The device has been tested in a Zeiss Merlin GEMINI II scanning electron microscope with Li 3 PS 4 samples, showing effective isolation from air and corrosion prevention.

  9. Tests of CMS Hadron Forward Calorimeter Upgrade Readout Box Prototype

    CERN Document Server

    Chatrchyan, Sergey; Sirunyan, Albert; Tumasyan, Armen; Mossolov, Vladimir; Shumeiko, Nikolai; Cornelis, Tom; Ochesanu, Silvia; Roland, Benoit Florent; Staykova, Zlatka; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Spilbeeck, Alex; Alves, Gilvan Augusto; Martins, Thiago Dos Reis; Pol, Maria Elena; Vaz Da Silva Filho, Mario; Alda Junior, Walter Luiz; Carvalho, Wagner De Paula; Chinellato, Jose Augusto; De Oliveira Martins, Carley Pedro; Figueiredo, Diego Matos; Tonelli Manganote, Edmilson Jose; Molina Insfran, Jorge Andres; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santoro, Alberto; Rosa Lopes Zachi, Alessandro; Finger, Miroslav; Finger, Michael; Tsamalaidze, Zviad; Borras, Kerstin; Gunnellini, Paolo; Jung, Hannes; Knutsson, Albert Hans; Lutz, Benjamin; Ribeiro Cipriano, Pedro Miguel; Sen, Niladri; Baus, Colin; Katkov, Igor; Ulrich, Ralf Matthias; Wohrmann, H; Panagiotou, Apostolos; Bencze, Gyorgy; Horvath, D; Bala, Suman; Gupta, Ruchi; Jindal, M; Lal, Manjit Kaur; Nishu, Nishu; Saini, Lovedeep Kaur; Banerjee, Sunanda; Bhattacharya, S; Gomber, Bhawna; Jain, Shilpi; Khurana, Raman; Sharan, Manoj Kumar; Aziz, Tariq; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Katta, Sudhakar; Banerjee, Sudeshna; Dugad, Shashikant Raichand; Etesami, Seyed Mohsen; Fahim, Ali; Jafari, Abideh; Paktinat Mehdiabadi, Saeid; Zeinali, Maryam; Penzo, Aldo; Afanasyev, A; Bunin, Pavel; Ershov, Yuri; Fedoseev, Oleg; Gavrilenko, Mikhail; Golutvin, Igor; Gorbunov, Ilya; Konoplynikov, V; Malakhov, Alexander; Moisenz, Petr; Smirnov, Vitaly; Volodko, Anton; Zarubin, Anatoly; Andreev, Yuri; Dermenev, Alexander; Krasnikov, Nikolay; Pashenkov, Anatoli; Tlisov, Danila; Toropin, A; Epshteyn, Vladimir; Erofeeva, Maria; Gavrilov, Vladimir; Kosov, Mikhail Vladimirovich; Kudinov, Ilya; Lychkovskaya, Natalia; Popov, V; Safronov, Grigory; Semenov, Sergey; Stolin, Viatcheslav; Vlassov, Evgueni; Zhokin, Alexander; Belyaev, A; Boos, Eduard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Korotkikh, Vladimir; Lokhtin, Igor; Markina, Anastasia; Obraztsov, Stepan; Perfilov, Maxim; Petrushanko, Sergey; Popov, Andrey; Savrin, Victor; Snigirev, Alexander; Vardanyan, Irina; Andreev, V; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Vinogradov, Alexey; Bayshev, Igor; Bityukov, Sergey; Grishin, Viatcheslav; Kryshkin, Victor; Petrov, V; Ryutin, Roman; Sobol, Andrey; Turchanovich, Leonid; Troshin, Sergey; Uzunyan, Andrey; Volkov, Alexey; Santanastasio, Francesco; Adiguzel, Aytul; Bakirci, Numan Mustafa; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; G�kbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Karapinar, Guler; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Latife Nukhet; Vergili, Mehmet; Aliyev, Takhmasib; Deniz, Muhammed; Guler, Ali Murat; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Zeyrek, Mehmet; Deliomeroglu, Mehmet; Gulmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Sonmez, Nasuf; Cankocak, Kerem; Levchuk, Leonid; Hatakeyama, Kenichi; Liu, H; Scarborough, Tara Ann; Rumerio, Paolo; Heister, Arno; Hill, C; Lawson, Philip Daniel; Lazic, Dragoslav; Rohlf, James; St. John, Jason; Sulak, Lawrence; Gennadiy, G; Laird, Edward; Landsberg, Greg; Narain, Meenakshi; Sinthuprasith, Tutanon; Tsang, Ka Vang; Long, Owen Rosser; Nguyen, Harold; Paramesvaran, Sudarshan; Sturdy, Jared; Stuart, David; To, Wing; West, Christopher Alan; Apresyan, Artur; Chen, Y; Mott, Alexander Robert; Spiropulu, Maria; Winn, David; Abdoulline, Salavat; Anderson, J; Chlebana, Frank; Freeman, James; Green, Daniel; Hanlon, J; Hirschauer, James Francis; Joshi, Umeshwar; Kunori, Shuichi; Musienko, Yuri; Sharma, Seema; Spalding, William Jeffrey; Tkaczyk, Slawomir; Vidal, Richard; Whitmore, Juliana; Wu, W; Gaultney, Vanessa; Linn, Stephan; Markowitz, Pete Edward; Martinez, German Ruben; Gleyzer, Sergei; Hagopian, Sharon Lee; Hagopian, Vasken; Jenkins, Charles Merrill; Baarmand, Marc M; Dorney, Brian L; Vodopiyanov, Igor; Akgun, Ugur; Albayrak, Elif Asli; Bilki, Burak; Clarida, Warren James; Duru, Firdevs; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony Richard; Nachtman, Jane; Newsom, Charles Ray; Norbeck, John Edwin; Olson, Jonathan Edward; Onel, Yasar; Ozok, Ferhat; Sen, Sercan; Schmidt, Ianos; Tiras, Emrah; Yetkin, Taylan; Yi, Kai; Kenny, Raymond Patrick; Murray, Michael Joseph; Wood, Jeffrey Scott; Baden, Andrew; Calvert, Brian Michael; Eno, Sarah Catherine; Gomez, Jaime Arturo; Grassi, Tullio; Hadley, Nicholas John; Kellogg, Richard; Kolberg, Ted; Lu, Y; Marionneau, Matthieu; Mignerey, Alice Louise Cox; Peterman, Alison Marie; Skuja, Andris; Temple, Jeffrey; Tonjes, Marguerite Belt; Kao, Shih-Chuan; Klapoetke, Kevin Humphrey; Mans, Jeremiah Michael; Pastika, Nathaniel Joseph; Kroeger, Robert; Rahmat, Rahmat; Sanders, David; Cremaldi, Lucien Marcus; Jain, S; Anastassov, Anton; Velasco, Mayda Marie; Won, Steven; Heering, Adriaan; Karmgard, Daniel; Pearson, Tessa Jae; Ruchti, Randal; Berry, Edmund A; Halyo, Valerie; Hebda, Philip; Hunt, Adam Paul; Lujan, Paul Joseph; Marlow, Daniel; Medvedeva, Tatiana; Saka, Halil; Tully, Christopher; Zuranski, Andrzej Maciej; Barnes, Virgil Everett; Laasanen, Alvin; Bodek, Arie; Chung, Yeon Sei; de Barbaro, Pawel Jan; Eshaq, Yossof; Garcia-bellido, Aran Angel; Goldenzweig, Pablo David; Han, Ji Yeon; Harel, Amnon; Miner, Daniel Carl; Vishnevskiy, Dmitry; Zielinski, Marek; Bhatti, Anwar; Ciesielski, Robert Adam; Flanagan, Will Hogan; Kamon, Teruki; Montalvo, Roy Joaquin; Sakuma, Tai; Akchurin, Nural; Damgov, Jordan; Dudero, Phillip Russell; Kovitanggoon, Kittikul; Lee, Sung Won; Libeiro, Terence; Volobouev, Igor; Gurrola, Alfredo; Milstene, Caroline

    2012-01-01

    A readout box prototype for CMS Hadron Forward calorimeter upgrade is built and tested in CERN H2 beamline. The prototype is designed to enable simultaneous tests of different readout options for the four anode upgrade PMTs, new front-end electronics design and new cabling. The response of the PMTs with different readout options is uniform and the background response is minimal. Multi-channel readout options further enhance the background elimination. Passing all the electronics, mechanical and physics tests, the readout box proves to be capable of providing the forward hadron calorimeter operations requirements in the upgrade era.

  10. Genomic organization, phylogenetic comparison and differential expression of the SBP-box family of transcription factors in tomato.

    Science.gov (United States)

    Salinas, María; Xing, Shuping; Höhmann, Susanne; Berndtgen, Rita; Huijser, Peter

    2012-06-01

    SBP-box genes represent transcription factors ubiquitously found in the plant kingdom and recognized as important regulators of many different aspects of plant development. In this study, 15 SBP-box gene family members were identified in tomato and analyzed with respect to their genomic organization and other structural features. Phylogenetic reconstruction based on the DNA-binding SBP-domain, allowed the classification of the SlySBP proteins into eight groups representing clear orthologous relationships to family members of other flowering plants and the moss Physcomitrella. In order to have a better understanding of their possible function in the development of a fleshy-fruit species like tomato, the mRNA expression levels of all SlySBP genes were quantified in vegetative and reproductive organs of plants, at different stages of growth. As transcripts of ten SlySBP genes were found to carry putative miR156- and miR157-response elements, the expression levels of the corresponding microRNAs were determined as well, revealing different patterns of expression. In addition, eight putative miR156 and four miR157 encoding loci could be identified in the tomato genome, four of them forming a polycistronic cluster. Whereas miR156 and miR157 levels were highest in seedlings, leaves and anthers of young flowers, most miR156-targeted SlySBP genes were found to be expressed in young inflorescences and during fruit development and ripening, suggesting a particularly important role during tomato reproductive growth. The data presented provide a basis for future clarification of the various functions that SBP-box gene family members play in tomato growth and development.

  11. Hydrogen embrittlement in power plant steels

    Indian Academy of Sciences (India)

    In power plants, several major components such as steam generator tubes, boilers, steam/water pipe lines, water box of condensers and the other auxiliary components like bolts, nuts, screws fasteners and supporting assemblies are commonly fabricated from plain carbon steels, as well as low and high alloy steels.

  12. Patterns of MADS-box gene expression mark flower-type development in Gerbera hybrida (Asteraceae

    Directory of Open Access Journals (Sweden)

    Teeri Teemu H

    2006-06-01

    Full Text Available Abstract Background The inflorescence of the cut-flower crop Gerbera hybrida (Asteraceae consists of two principal flower types, ray and disc, which form a tightly packed head, or capitulum. Despite great interest in plant morphological evolution and the tractability of the gerbera system, very little is known regarding genetic mechanisms involved in flower type specification. Here, we provide comparative staging of ray and disc flower development and microarray screening for differentially expressed genes, accomplished via microdissection of hundreds of coordinately developing flower primordia. Results Using a 9K gerbera cDNA microarray we identified a number of genes with putative specificity to individual flower types. Intrestingly, several of these encode homologs of MADS-box transcription factors otherwise known to regulate flower organ development. From these and previously obtained data, we hypothesize the functions and protein-protein interactions of several gerbera MADS-box factors. Conclusion Our RNA expression results suggest that flower-type specific MADS protein complexes may play a central role in differential development of ray and disc flowers across the gerbera capitulum, and that some commonality is shared with known protein functions in floral organ determination. These findings support the intriguing conjecture that the gerbera flowering head is more than a mere floral analog at the level of gene regulation.

  13. Evolutionary Analysis of MIKCc-Type MADS-Box Genes in Gymnosperms and Angiosperms

    Directory of Open Access Journals (Sweden)

    Fei Chen

    2017-05-01

    Full Text Available MIKCc-type MADS-box genes encode transcription factors that control floral organ morphogenesis and flowering time in flowering plants. Here, in order to determine when the subfamilies of MIKCc originated and their early evolutionary trajectory, we sampled and analyzed the genomes and large-scale transcriptomes representing all the orders of gymnosperms and basal angiosperms. Through phylogenetic inference, the MIKCc-type MADS-box genes were subdivided into 14 monophyletic clades. Among them, the gymnosperm orthologs of AGL6, SEP, AP1, GMADS, SOC1, AGL32, AP3/PI, SVP, AGL15, ANR1, and AG were identified. We identified and characterized the origin of a novel subfamily GMADS within gymnosperms but lost orthologs in monocots and Brassicaceae. ABCE model prototype genes were relatively conserved in terms of gene number in gymnosperms, but expanded in angiosperms, whereas SVP, SOC1, and GMADS had dramatic expansions in gymnosperms but conserved in angiosperms. Our results provided the most detailed evolutionary history of all MIKCc gene clades in gymnosperms and angiosperms. We proposed that although the near complete set of MIKCc genes had evolved in gymnosperms, the duplication and expressional transition of ABCE model MIKCc genes in the ancestor of angiosperms triggered the first flower.

  14. Evolutionary Analysis of MIKCc-Type MADS-Box Genes in Gymnosperms and Angiosperms

    Science.gov (United States)

    Chen, Fei; Zhang, Xingtan; Liu, Xing; Zhang, Liangsheng

    2017-01-01

    MIKCc-type MADS-box genes encode transcription factors that control floral organ morphogenesis and flowering time in flowering plants. Here, in order to determine when the subfamilies of MIKCc originated and their early evolutionary trajectory, we sampled and analyzed the genomes and large-scale transcriptomes representing all the orders of gymnosperms and basal angiosperms. Through phylogenetic inference, the MIKCc-type MADS-box genes were subdivided into 14 monophyletic clades. Among them, the gymnosperm orthologs of AGL6, SEP, AP1, GMADS, SOC1, AGL32, AP3/PI, SVP, AGL15, ANR1, and AG were identified. We identified and characterized the origin of a novel subfamily GMADS within gymnosperms but lost orthologs in monocots and Brassicaceae. ABCE model prototype genes were relatively conserved in terms of gene number in gymnosperms, but expanded in angiosperms, whereas SVP, SOC1, and GMADS had dramatic expansions in gymnosperms but conserved in angiosperms. Our results provided the most detailed evolutionary history of all MIKCc gene clades in gymnosperms and angiosperms. We proposed that although the near complete set of MIKCc genes had evolved in gymnosperms, the duplication and expressional transition of ABCE model MIKCc genes in the ancestor of angiosperms triggered the first flower. PMID:28611810

  15. Bioprospecting plant-associated microbiomes.

    Science.gov (United States)

    Müller, Christina A; Obermeier, Melanie M; Berg, Gabriele

    2016-10-10

    There is growing demand for new bioactive compounds and biologicals for the pharmaceutical, agro- and food industries. Plant-associated microbes present an attractive and promising source to this end, but are nearly unexploited. Therefore, bioprospecting of plant microbiomes is gaining more and more attention. Due to their highly specialized and co-evolved genetic pool, plant microbiomes host a rich secondary metabolism. This article highlights the potential detection and use of secondary metabolites and enzymes derived from plant-associated microorganisms in biotechnology. As an example we summarize the findings from the moss microbiome with special focus on the genus Sphagnum and its biotechnological potential for the discovery of novel microorganisms and bioactive molecules. The selected examples illustrate unique and yet untapped properties of plant-associated microbiomes, which are an immense treasure box for future research. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Printing of the year book, carton boxes and printed envelopes

    Indian Academy of Sciences (India)

    2018-01-18

    Jan 18, 2018 ... 1. Title: PRINTING AND SUPPLY OF THE YEAR BOOK - 2018 AND CARTON BOXES ALONG WITH PRINTED. ENVELOPES. Description a) Book size: : 140 X 215 mm / 22.5 cm x 15 cm (Trim Size) b) No. of Pages. : 340 + 4 in DOUBLE COLOUR c) Inner Pages. Matt Art 100 GSM. 2) Natural shade (NS), ...

  17. Pandora's Box: Academic Perceptions of Student Plagiarism in Writing

    Science.gov (United States)

    Sutherland-Smith, Wendy

    2005-01-01

    Plagiarism is viewed by many academics as a kind of Pandora's box--the elements contained inside are too frightening to allow escape for fear of the havoc that may result. Reluctance by academic members of staff to discuss student plagiarism openly may contribute to the often untenable situations we, as teachers, face when dealing with student…

  18. Efficient approximation of black-box functions and Pareto sets

    NARCIS (Netherlands)

    Rennen, G.

    2009-01-01

    In the case of time-consuming simulation models or other so-called black-box functions, we determine a metamodel which approximates the relation between the input- and output-variables of the simulation model. To solve multi-objective optimization problems, we approximate the Pareto set, i.e. the

  19. Fitting boxes to Manhattan scenes using linear integer programming

    KAUST Repository

    Li, Minglei

    2016-02-19

    We propose an approach for automatic generation of building models by assembling a set of boxes using a Manhattan-world assumption. The method first aligns the point cloud with a per-building local coordinate system, and then fits axis-aligned planes to the point cloud through an iterative regularization process. The refined planes partition the space of the data into a series of compact cubic cells (candidate boxes) spanning the entire 3D space of the input data. We then choose to approximate the target building by the assembly of a subset of these candidate boxes using a binary linear programming formulation. The objective function is designed to maximize the point cloud coverage and the compactness of the final model. Finally, all selected boxes are merged into a lightweight polygonal mesh model, which is suitable for interactive visualization of large scale urban scenes. Experimental results and a comparison with state-of-the-art methods demonstrate the effectiveness of the proposed framework.

  20. 49 CFR 178.516 - Standards for fiberboard boxes.

    Science.gov (United States)

    2010-10-01

    ... are as follows: (1) Strong, solid or double-faced corrugated fiberboard (single or multi-wall) must be... suitable material may be used. (3) Manufacturing joints. (i) Manufacturing joints in the bodies of boxes must be— (A) Taped; (B) Lapped and glued; or (C) Lapped and stitched with metal staples. (ii) Lapped...

  1. Optimal Black-Box Secret Sharing over Arbitrary Abelian Groups

    DEFF Research Database (Denmark)

    Cramer, Ronald; Fehr, Serge

    2002-01-01

    A black-box secret sharing scheme for the threshold access structure T t,n is one which works over any finite Abelian group G. Briefly, such a scheme differs from an ordinary linear secret sharing scheme (over, say, a given finite field) in that distribution matrix and reconstruction vectors are ...

  2. The Box Model and the Acoustic Sounder, a Case Study

    DEFF Research Database (Denmark)

    Jensen, Niels Otto; Lundtang Petersen, Erik

    1979-01-01

    Concentrations of SO2 in a large city during a subsidence situation are predicted as a function of time by means of a simple box model and the predictions are compared to actual SO2 concentration measurements. The agreement between model results and measurements is found to be excellent. The model...

  3. 49 CFR 178.517 - Standards for plastic boxes.

    Science.gov (United States)

    2010-10-01

    ... carbon black or other suitable pigments or inhibitors. These additives must be compatible with the contents and remain effective throughout the life of the box. Where use is made of carbon black pigment or... carbon black content does not exceed 2 percent by mass or if the pigment content does not exceed 3...

  4. A QQ→QQ planar double box in canonical form

    Directory of Open Access Journals (Sweden)

    Marco S. Bianchi

    2018-02-01

    Full Text Available We consider a planar double box with four massive external momenta and two massive internal propagators. We derive the system of differential equations for the relevant master integrals, cast it in canonical form, write it as a dlog form and solve it in terms of iterated integrals up to depth four.

  5. The energetics of semicontact 3 x 2-min amateur boxing.

    Science.gov (United States)

    Davis, Philip; Leithäuser, Renate M; Beneke, Ralph

    2014-03-01

    The energy expenditure of amateur boxing is unknown. Total metabolic cost (Wtot) as an aggregate of aerobic (Waer), anaerobic lactic (W[lactate]), and anaerobic alactic (WPCr) energy of a 3 × 2-min semicontact amateur boxing bout was analyzed. Ten boxers (mean ± SD [lower/upper 95% confidence intervals]) age 23.7 ± 4.1 (20.8/26.6) y, height 180.2 ± 7.0 (175.2/185.2) cm, body mass 70.6 ± 5.7 (66.5/74.7) kg performed a semicontact bout against handheld pads created from previously analyzed video footage of competitive bouts. Net metabolic energy was calculated using respiratory gases and blood [lactate]. Waer, 526.0 ± 57.1 (485.1/566.9) kJ, was higher (P amateur boxing is predominantly aerobic. They also highlight the importance of a highly developed aerobic capacity as a prerequisite of a high activity rate during rounds and recovery of the high-energy phosphate system during breaks as interrelated requirements of successful boxing.

  6. Detection of early squats by axle box acceleration

    NARCIS (Netherlands)

    Molodova, M.

    2013-01-01

    This thesis discusses a new method for detection of short track irregularities, particularly squats, with axle box acceleration (ABA) measurements. A squat is a surface initiated short track defect, associated with high frequency vibrations of the wheel-rail system. High stresses in the contact

  7. Review of Elastic Analysis of Box Girder Bridges | Ezeokpube ...

    African Journals Online (AJOL)

    The importance of thin-walled box girder bridges has attracted the attention of researchers since the last five decades. A lot of literature has dealt with the analytical formulations as well as experimental investigations. Field studies have increased tremendously in the last decade. So far the agreement between the analytical ...

  8. Developing Box Plots While Navigating the Maze of Data Representations

    Science.gov (United States)

    Duncan, Bruce; Fitzallen, Noleine

    2013-01-01

    The learning sequence described in this article was developed to provide students with a demonstration of the development of box plots from authentic data as an illustration of the advantages gained from using multiple forms of data representation. The sequence follows an authentic process that starts with a problem to which data representations…

  9. Box-and-Whisker Plots Applied to Food Chemistry

    Science.gov (United States)

    Ferreira, Joao E. V.; Miranda, Ricardo M.; Figueiredo, Antonio F.; Barbosa, Jardel P.; Brasil, Edykarlos M.

    2016-01-01

    Box-and-whisker plots or simply boxplots are powerful graphical representations that give an overview of a data set. In this work five different examples illustrate the applications of boxplots in food chemistry. The examples involve relative sweetness of sugars and sugar alcohols with respect to sucrose, the potassium content of fruits and…

  10. Department of Geology University of Ghana, Box LG 58, Legon

    African Journals Online (AJOL)

    T.M. AKABZAA", B.K. BANEONG-YAKUBO and T.E.K. ARMAH. Department of Geology University of Ghana, Box LG 58, Legon, Ghana. (Submitted: 12 March 2005; Accepted: 15 August 2005). Abstract. The distribution and sources of mercury in the Ankobra River Basin and the Bonsa River Sub-basin in the. Wassa West ...

  11. Preferences for nest boxes as environmental enrichment for laboratory mice

    NARCIS (Netherlands)

    Van de Weerd, HA; Van Loo, PLP; Van Zutphen, LFM; Koolhaas, JM; Baumans, [No Value

    In nature, mice live in burrows with nest chambers where they breed and may hide from predators. In the laboratory, a shelter or refuge is an easily applicable form of enrichment which may enhance the welfare of laboratory mice by giving them more control over their environment. Six nest boxes made

  12. A Grey Box Model for the Hydraulics in a Creek

    DEFF Research Database (Denmark)

    Jonsdottir, Harpa; Jacobsen, Judith L.; Madsen, Henrik

    1998-01-01

    The Saint-Venant equation of mass balance is used to derive a stochastics lumped model, describing the dynamics of a cross-sectional area in a river. The unknown parameters of the model are estimated by combining the physical equation with a set of data, a method known as grey box modelling...

  13. MADS-box gene evolution-structure and transcription patterns

    DEFF Research Database (Denmark)

    Johansen, Bo; Pedersen, Louise B; Skipper, Martin

    2002-01-01

    This study presents a phylogenetic analysis of 198 MADS-box genes based on 420 parsimony-informative characters. The analysis includes only MIKC genes; therefore several genes from gymnosperms and pteridophytes are excluded. The strict consensus tree identifies all major monophyletic groups known...

  14. Features for Exploiting Black-Box Optimization Problem Structure

    DEFF Research Database (Denmark)

    Tierney, Kevin; Malitsky, Yuri; Abell, Tinus

    2013-01-01

    Black-box optimization (BBO) problems arise in numerous scientic and engineering applications and are characterized by compu- tationally intensive objective functions, which severely limit the number of evaluations that can be performed. We present a robust set of features that analyze the tness...

  15. Immunohistochemical evidence for multiple photosystems in box jellyfish.

    Science.gov (United States)

    Ekström, Peter; Garm, Anders; Pålsson, Jonas; Vihtelic, Thomas S; Nilsson, Dan-Eric

    2008-07-01

    Cubomedusae (box jellyfish) possess a remarkable visual system with 24 eyes distributed in four sensory structures termed rhopalia. Each rhopalium is equipped with six eyes: two pairs of pigment cup eyes and two unpaired lens eyes. Each eye type probably captures specific features of the visual environment. To investigate whether multiple types of photoreceptor cells are present in the rhopalium, and whether the different eye types possess different types of photoreceptors, we have used immunohistochemistry with a range of vertebrate opsin antibodies to label the photoreceptors, and electroretinograms (ERG) to determine their spectral sensitivity. All photoreceptor cells of the two lens eyes of the box jellyfish Tripedalia cystophora and Carybdea marsupialis displayed immunoreactivity for an antibody directed against the zebrafish ultraviolet (UV) opsin, but not against any of eight other rhodopsin or cone opsin antibodies tested. In neither of the two species were the pigment cup eyes immunoreactive for any of the opsin antibodies. ERG analysis of the Carybdea lower lens eyes demonstrated a single spectral sensitivity maximum at 485 nm suggesting the presence of a single opsin type. Our data demonstrate that the lens eyes of box jellyfish utilize a single opsin and are thus color-blind, and that there is probably a different photopigment in the pigment cup eyes. The results support our hypothesis that the lens eyes and the pigment cup eyes of box jellyfish are involved in different and specific visual tasks.

  16. The Popcorn Box Activity and Reasoning about Optimization

    Science.gov (United States)

    Whiteley, Walter J.; Mamolo, Ami

    2012-01-01

    A well-known optimization problem is the Popcorn Box investigation, which involves a movie theater snack container. The problem has been tailored for classroom investigations by the Ontario Association for Mathematics Education. The exploration was designed for students in grades 9 through 12. A common strategy proposed for algebra students is to…

  17. Testing the Box-Cox Parameter for an Integrated Process

    NARCIS (Netherlands)

    J. Huang (Jian); M. Kobayashi (Masahito); M.J. McAleer (Michael)

    2011-01-01

    textabstractThis paper analyses the constant elasticity of volatility (CEV) model suggested by Chan et al. (1992). The CEV model without mean reversion is shown to be the inverse Box-Cox transformation of integrated processes asymptotically. It is demonstrated that the maximum likelihood estimator

  18. Learning unions of boxes with membership and equivalence queries

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, P.W. [Sandia National Laboratories, Albuquerque, NM (United States); Goldman, S.A.; Mathias, H.D. [Washington Univ., St. Louis, MO (United States)

    1994-07-01

    The authors present two algorithms that use membership and equivalence queries to exactly identify the concepts given by the union of s discretized axis-parallel boxes in d-dimensional discretized Euclidean space where there are n discrete values that each coordinate can have. The first algorithm receives at most sd counterexamples and uses time and membership queries polynomial in s and log n for d any constant. Further, all equivalence queries made can be formulated as the union of O(sd log(s)) axis-parallel boxes. Next, they introduce a new complexity measure that better captures the complexity of a union of boxes than simply the number of boxes and dimensions. Their new measure, {sigma}, is the number of segments in the target polyhedron where a segment is a maximum portion of one of the sides of the polyhedron that lies entirely inside or entirely outside each of the other halfspaces defining the polyhedron. They then present an improvement of their first algorithm that uses time and queries polynomial in {sigma} and log n. The hypothesis class used here is decision trees of height at most 2sd. Further they can show that the time and queries used by this algorithm are polynomial in d and log n for s any constant thus generalizing the exact learnability of DNF formulas with a constant number of terms. In fact, this single algorithm is efficient for either s or d constant.

  19. How Users Search the Library from a Single Search Box

    Science.gov (United States)

    Lown, Cory; Sierra, Tito; Boyer, Josh

    2013-01-01

    Academic libraries are turning increasingly to unified search solutions to simplify search and discovery of library resources. Unfortunately, very little research has been published on library user search behavior in single search box environments. This study examines how users search a large public university library using a prominent, single…

  20. Seismic vulnerability assessment of a continuous steel box girder ...

    Indian Academy of Sciences (India)

    Tae-Hyung Lee

    2018-02-07

    Feb 7, 2018 ... indicate that the bridge structures equipped with seismic isolation devices (e.g. LRBs) significantly mitigated the damages due to earthquakes. Keywords. Continuous steel box girder bridge; fragility curves; seismic vulnerability assessment; damage state; nonlinear dynamic analysis; lead rubber bearing. 1.

  1. Application of Box-Behnken Design for Optimum Citric Acid ...

    African Journals Online (AJOL)

    The effect of three factors, temperature, pH and inoculum density on citric acid production was determined using a three variable Box-Behnken design (BBD). The BBD was used to develop a statistical model to describe the production of citric acid and the fermentation conditions were then optimised using RSM. The model ...

  2. Evaluating degradation at railway crossings using axle box acceleration measurements

    NARCIS (Netherlands)

    Wei, Z.; Nunez Vicencio, Alfredo; Li, Z.; Dollevoet, R.P.B.J.

    2017-01-01

    In this paper, we investigate the capability of an axle box acceleration (ABA) system to evaluate the degradation at railway crossings. For this purpose, information from multiple sensors, namely, ABA signals, 3D rail profiles, Global Positioning System (GPS) and tachometer recordings, was

  3. 49 CFR 178.515 - Standards for reconstituted wood boxes.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Standards for reconstituted wood boxes. 178.515 Section 178.515 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR PACKAGINGS Non-bulk Performance-Oriente...

  4. Optimizing PHB and Protease Production by Box Behnken Design

    Directory of Open Access Journals (Sweden)

    Amro Abd al fattah Amara

    2013-04-01

    Full Text Available Mixed culture is more suitable to adapt more flexible fermentation process and produce different product simultaneously. In this study a mixed Bacillus culture was investigated for their ability to produce the bioplastic "Polyhydroxybutyrate" and both of the mesophilic and the thermophilic proteases in one flask. Box-Behnken experimental design was used. The produced amount of PHB has been increased significantly. Meanwhile there is a competition between PHB and proteases. The maximum produced amount of PHB using Box-Behnken design was 2.82 g/l/48 h with protease activity equal to 41.9 Units/ml/48 h for thermophilic proteases and 99.65 Units/ml/48 h for mesophilic proteases. Excel solver was used for extra-optimization for the optimum conditions obtained from Box-Behnken experiments and its model. The maximum PHB obtained after using Excel solver was 2.88 g/l/48 h. The maximum mesophilic and thermophilic activities obtained at the same PHB production conditions were 175.68 and 243.38 Units/ml respectively. The model accuracy as obtained from Excel solver was 118.8%, which prove the power of the experimental design in optimizing such complicated process. The strategies used in this study are recommended for the production of PHB and different proteases simultaneously using Bacillus mixed culture. ABSTRAK: Kultur campuran adalah lebih sesuai bagi proses penapaian yang fleksibel dan ia boleh menghasilkan produk yang berbeza secara serentak. Dalam kajian ini keupayaan  menghasilkan "Polyhydroxybutyrate" bioplastik serta mesofilik dan termofilik protease dalam satu flask oleh  kultur Bacillus campuran telah disiasat. Eksperimen rekabentuk Box-Behnken telah digunakan. Jumlah PHB yang dikeluarkan meningkat dengan ketara dan terdapat persaingan antara PHB dan protease. Jumlah keluaran PHB maksima menggunakan rekabentuk Box-Behnken adalah 2.82 g/l/48 jam dengan aktiviti protease sama dengan 41.9 Unit/ml/48 jam untuk protease termofilik dan 99.65 Unit

  5. Thinking out of the box: MADS-box genes and maize spikelet ...

    African Journals Online (AJOL)

    Due to the importance of maize as an agricultural crop and its stature as an ideal model plant for the study of developmental biology in monocots, it is natural that research into its genetic structure has gained worldwide attention. Unfortunately, although much progress has been made in our understanding of the genetic ...

  6. DTH8 Suppresses Flowering in Rice, Influencing Plant Height and Yield Potential Simultaneously

    National Research Council Canada - National Science Library

    Xiangjin Wei; Junfeng Xu; Hongnian Guo; Ling Jiang; Saihua Chen; Chuanyuan Yu; Zhenling Zhou; Peisong Hu; Huqu Zhai; Jianmin Wan

    2010-01-01

    .... Map-based cloning reveals that DTH8 encodes a putative HAP3 subunit of the CCAAT-box-binding transcription factor and the complementary experiment increased significantly days to heading, plant...

  7. Analysis of S-box in Image Encryption Using Root Mean Square Error Method

    Science.gov (United States)

    Hussain, Iqtadar; Shah, Tariq; Gondal, Muhammad Asif; Mahmood, Hasan

    2012-07-01

    The use of substitution boxes (S-boxes) in encryption applications has proven to be an effective nonlinear component in creating confusion and randomness. The S-box is evolving and many variants appear in literature, which include advanced encryption standard (AES) S-box, affine power affine (APA) S-box, Skipjack S-box, Gray S-box, Lui J S-box, residue prime number S-box, Xyi S-box, and S8 S-box. These S-boxes have algebraic and statistical properties which distinguish them from each other in terms of encryption strength. In some circumstances, the parameters from algebraic and statistical analysis yield results which do not provide clear evidence in distinguishing an S-box for an application to a particular set of data. In image encryption applications, the use of S-boxes needs special care because the visual analysis and perception of a viewer can sometimes identify artifacts embedded in the image. In addition to existing algebraic and statistical analysis already used for image encryption applications, we propose an application of root mean square error technique, which further elaborates the results and enables the analyst to vividly distinguish between the performances of various S-boxes. While the use of the root mean square error analysis in statistics has proven to be effective in determining the difference in original data and the processed data, its use in image encryption has shown promising results in estimating the strength of the encryption method. In this paper, we show the application of the root mean square error analysis to S-box image encryption. The parameters from this analysis are used in determining the strength of S-boxes

  8. T Plant overpack tiedown analysis

    Energy Technology Data Exchange (ETDEWEB)

    Riley, D.L.

    2000-07-31

    This tiedown evaluation meets the requirement imposed by HNF-6550, Safety Evaluation for Packaging (Onsite) T Plant Canyon Items, (O'Brien 2000). O'Brien (2000) requires that any items prepared for shipment from T Plant to the burial grounds that are not bounded by the analysis in O'Brien (2000) must have a separate, approved, engineered tiedown analysis. The width of the overpack box is 9 ft. 7 in. This width is wider than the maximum width authorized in O'Brien (2000), which is 8 ft.

  9. Analysis of CFB, a cytokinin-responsive gene of Arabidopsis thaliana encoding a novel F-box protein regulating sterol biosynthesis.

    Science.gov (United States)

    Brenner, Wolfram G; Leuendorf, Jan Erik; Cortleven, Anne; Martin, Laetitia B B; Schaller, Hubert; Schmülling, Thomas

    2017-05-17

    Protein degradation by the ubiquitin-26S proteasome pathway is important for the regulation of cellular processes, but the function of most F-box proteins relevant to substrate recognition is unknown. We describe the analysis of the gene Cytokinin-induced F-box encoding (CFB, AT3G44326), identified in a meta-analysis of cytokinin-related transcriptome studies as one of the most robust cytokinin response genes. F-box domain-dependent interaction with the E3 ubiquitin ligase complex component ASK1 classifies CFB as a functional F-box protein. Apart from F-box and transmembrane domains, CFB contains no known functional domains. CFB is expressed in all plant tissues, predominantly in root tissue. A ProCFB:GFP-GUS fusion gene showed strongest expression in the lateral root cap and during lateral root formation. CFB-GFP fusion proteins were mainly localized in the nucleus and the cytosol but also at the plasma membrane. cfb mutants had no discernible phenotype, but CFB overexpressing plants showed several defects, such as a white upper inflorescence stem, similar to the hypomorphic cycloartenol synthase mutant cas1-1. Both CFB overexpressing plants and cas1-1 mutants accumulated the CAS1 substrate 2,3-oxidosqualene in the white stem tissue, the latter even more after cytokinin treatment, indicating impairment of CAS1 function. This suggests that CFB may link cytokinin and the sterol biosynthesis pathway. © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  10. Simultaneous determination of the bilirubin oxidation end products Z-BOX A and Z-BOX B in human serum using liquid chromatography coupled to tandem mass spectrometry.

    Science.gov (United States)

    Seidel, Raphael A; Kahnes, Marcel; Bauer, Michael; Pohnert, Georg

    2015-01-01

    Bilirubin oxidation end products (BOXes) appear upon endogenous heme degradation and can be found in the cerebrospinal fluid after hemorrhagic stroke. BOXes are assumed to contribute to delayed cerebral vasospasm and secondary loss of brain tissue. Here, we present a validated LC-ESI-MS/MS method for the sensitive determination of the regio-isomers Z-BOX A and Z-BOX B in human serum. We found that Z-BOX A and Z-BOX B appear in serum of healthy volunteers. The sample preparation includes the addition of 5-bromonicotinamide as internal standard and protein precipitation with acetonitrile. Baseline-separation was achieved on a C-18 column with a binary solvent gradient of formic acid in water/acetonitrile at 1 mL/min within a total analysis time of 17 min. Using single reaction monitoring in the positive ion mode, the linear working ranges were 2.74-163 pg/μL (Z-BOX A) and 2.12-162.4 pg/μL (Z-BOX B) with R(2)>0.995. Intra- and inter-day precisions were human serum were determined by standard addition. The photolability of both analytes was demonstrated. This method enables to monitor Z-BOX A and Z-BOX B as a prerequisite to systematically study the biological significance of higher order metabolites of heme degradation. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. 77 FR 38705 - Draft Specification for Airport Light Bases, Transformer Housings, Junction Boxes, and...

    Science.gov (United States)

    2012-06-28

    ... Federal Aviation Administration Draft Specification for Airport Light Bases, Transformer Housings... comment on the Draft ``Specification for Airport Light Bases, Transformer Housings, Junction Boxes, and... recommendations for airport light bases, transformer housings, junction boxes and accessories. The FAA has posted...

  12. Using Bounding-Surrounding Boxes Method for Fish Tracking in Real World Underwater Observation

    Directory of Open Access Journals (Sweden)

    Yi-Haur Shiau

    2013-07-01

    Full Text Available The purpose of this paper is to present a rapid and efficient fish tracking method suitable for real world automatic underwater fish observation. Based on fish tracking, biologists are able to observe fish and their ecological environment. A distributed real-time underwater video stream system has been developed in Taiwan for large-scale, long-term ecological observation. In addition, not only does the system archive video data, but also incorporates data analysis. However, it is difficult to discriminate moving fish from drift water plants due to the severe drift of water plants caused by the water flow in real world underwater environments. Thus, fish tracking is complicated in unconstrained water. In order to overcome this problem, we propose a bounding-surrounding boxes method, which enables integration with state-of-the-art tracking methods for fish tracking in this paper. According to the method, fixing cameras must be used so that the moving fish are classified as foreground objects and are tracked, whereas the drifting water plants are classified as the background objects and are removed from the tracked objects. It enables the efficient, rapid removal of irrelevant information (non-fish objects from large-scale fish video data. Experimental results show that the proposed method is able to achieve high accuracy.

  13. An Arabidopsis F-box protein acts as a transcriptional co-factor to regulate floral development.

    Science.gov (United States)

    Chae, Eunyoung; Tan, Queenie K-G; Hill, Theresa A; Irish, Vivian F

    2008-04-01

    Plants flower in response to both environmental and endogenous signals. The Arabidopsis LEAFY (LFY) transcription factor is crucial in integrating these signals, and acts in part by activating the expression of multiple floral homeotic genes. LFY-dependent activation of the homeotic APETALA3 (AP3) gene requires the activity of UNUSUAL FLORAL ORGANS (UFO), an F-box component of an SCF ubiquitin ligase, yet how this regulation is effected has remained unclear. Here, we show that UFO physically interacts with LFY both in vitro and in vivo, and this interaction is necessary to recruit UFO to the AP3 promoter. Furthermore, a transcriptional repressor domain fused to UFO reduces endogenous LFY activity in plants, supporting the idea that UFO acts as part of a transcriptional complex at the AP3 promoter. Moreover, chemical or genetic disruption of proteasome activity compromises LFY-dependent AP3 activation, indicating that protein degradation is required to promote LFY activity. These results define an unexpected role for an F-box protein in functioning as a DNA-associated transcriptional co-factor in regulating floral homeotic gene expression. These results suggest a novel mechanism for promoting flower development via protein degradation and concomitant activation of the LFY transcription factor. This mechanism may be widely conserved, as homologs of UFO and LFY have been identified in a wide array of plant species.

  14. Fauna using nest boxes in four timber types in eastern Texas

    Science.gov (United States)

    Richard N. Conner; Daniel Saenz; D. Craig Rudolph

    1995-01-01

    Occupancy of 240 nest boxes in pure pine, pine-hardwood, upland hardwood, and bottomland hardwood forests (60 boxes in each forest type) were monitored for six years on the Stephen F. Austin Experimental Forest, Nacogdoches County in eastern Texas. Three boxes were placed at twenty sites in each forest type. Initially, each site had a box with 3.2, 4.7, or 5.7 cm...

  15. Visual pigment in the lens eyes of the box jellyfish Chiropsella bronzie

    OpenAIRE

    O'Connor, Megan; Garm, Anders; Marshall, Justin N.; Hart, Nathan S.; Ekström, Peter; Skogh, Charlotta; Nilsson, Dan-Eric

    2010-01-01

    Box jellyfish (Cubomedusae) possess a unique visual system comprising 24 eyes of four morphological types. Moreover, box jellyfish display several visually guided behaviours, including obstacle avoidance and light-shaft attractance. It is largely unknown what kind of visual information box jellyfish use for carrying out these behaviours. Brightness contrast is almost certainly involved, but it is also possible that box jellyfish extract colour information from their surroundings. The possible...

  16. Spatial root distribution of plants growing in vertical media for use in living walls

    DEFF Research Database (Denmark)

    Jørgensen, Lars; Dresbøll, Dorte Bodin; Thorup-Kristensen, Kristian

    2014-01-01

    of rockwool) in transparent boxes under greenhouse conditions. Root frequency was registered and the activity of individual root systems was studied via 15N uptake and plant dry weight was measured. Results: Plants in coir had stronger root growth in all parts of the medium than plants in rockwool. Upwards...

  17. 76 FR 40849 - Post Office (PO) Box Fee Groups for Merged Locations

    Science.gov (United States)

    2011-07-12

    ... 111 Post Office (PO) Box Fee Groups for Merged Locations AGENCY: Postal Service. TM ACTION: Proposed... Service, Domestic Mail Manual (DMM ) 508.4 to allow Post Office TM (PO) Box fee groups to be merged due to... , with a subject line of ``PO Box Fee Group for Merged Locations.'' Faxed comments are not accepted. FOR...

  18. Autoantibodies to high mobility group box 1 in patients with Incomplete and Systemic Lupus Erythematosus

    NARCIS (Netherlands)

    Schaper, F.; De Leeuw, K.; Horst, G.; Maas, F.; Beijeren, D.V.; Bijzet, J.; Heeringa, P.; Limburg, P.C.; Westra, J.

    2015-01-01

    Introduction. High Mobility Group Box-1 (HMGB1) is involved in the pathogenesis of Systemic Lupus Erythematosus (SLE). However, the role of autoantibodies to HMGB1 is unclear. Therefore levels of anti-HMGB1 and their reactivity to HMGB1 BoxA and BoxB were examined in association with disease

  19. Is Think Outside the Box 21st Century Code for Imagination, Innovation, Creativity, Critical Thinking, Intuition?

    Science.gov (United States)

    Notar, Charles E.; Padgett, Sharon

    2010-01-01

    It is the authors' contention that there is no such thing as "thinking outside the box." However, the term has become an iconic phrase for a generation. The discussion presents the authors' thoughts on why there is no box in which to think outside. If there is a box, then accidental learning would never exist for students.

  20. The Use of a Pica Box in Reducing Pica Behavior in a Student with Autism.

    Science.gov (United States)

    Hirsch, Nancy; Myles, Brenda Smith

    1996-01-01

    A pica box (containing items safe to chew) was used as an intervention with a 10-year-old autistic girl with pica behaviors in a special education setting. Evaluation using an ABAB design (varying in availability of the pica box) found a decrease in pica attempts when the pica box was available to the student. (DB)

  1. 49 CFR 230.63 - Smoke box, steam pipes and pressure parts.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Boilers and Appurtenances Steam Pipes § 230.63 Smoke box, steam pipes and pressure parts. The smoke box, steam pipes and... 49 Transportation 4 2010-10-01 2010-10-01 false Smoke box, steam pipes and pressure parts. 230.63...

  2. Limit theorems for the number of occupied boxes in the Bernoulli sieve

    NARCIS (Netherlands)

    Gnedin, A.V.; Iksanov, A.; Marynych, O.

    2010-01-01

    The Bernoulli sieve is a version of the classical `balls-in-boxes' occupancy scheme, in which random frequencies of in¯nitely many boxes are produced by a multiplicative renewal process, also known as the residual allocation model or stick-breaking. We focus on the number Kn of boxes occupied by at

  3. Combining Multiple External Representations and Refutational Text: An Intervention on Learning to Interpret Box Plots

    Science.gov (United States)

    Lem, Stephanie; Kempen, Goya; Ceulemans, Eva; Onghena, Patrick; Verschaffel, Lieven; Van Dooren, Wim

    2015-01-01

    Box plots are frequently misinterpreted and educational attempts to correct these misinterpretations have not been successful. In this study, we used two instructional techniques that seemed powerful to change the misinterpretation of the area of the box in box plots, both separately and in combination, leading to three experimental conditions,…

  4. Visual control of steering in the box jellyfish Tripedalia cystophora

    DEFF Research Database (Denmark)

    Petie, Ronald; Garm, Anders; Nilsson, Dan-Eric

    2011-01-01

    Box jellyfish carry an elaborate visual system consisting of 24 eyes, which they use for driving a number of behaviours. However, it is not known how visual input controls the swimming behaviour. In this study we exposed the Caribbean box jellyfish Tripedalia cystophora to simple visual stimuli...... and recorded changes in their swimming behaviour. Animals were tethered in a small experimental chamber, where we could control lighting conditions. The behaviour of the animals was quantified by tracking the movements of the bell, using a high-speed camera. We found that the animals respond predictably...... their bell in such a way that, if not tethered, they would turn and swim away from the dark area. We conclude that the visual system of T. cystophora has a predictable effect on swimming behaviour....

  5. Safeguards Approaches for Black Box Processes or Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Diaz-Marcano, Helly; Gitau, Ernest TN; Hockert, John; Miller, Erin; Wylie, Joann

    2013-09-25

    The objective of this study is to determine whether a safeguards approach can be developed for “black box” processes or facilities. These are facilities where a State or operator may limit IAEA access to specific processes or portions of a facility; in other cases, the IAEA may be prohibited access to the entire facility. The determination of whether a black box process or facility is safeguardable is dependent upon the details of the process type, design, and layout; the specific limitations on inspector access; and the restrictions placed upon the design information that can be provided to the IAEA. This analysis identified the necessary conditions for safeguardability of black box processes and facilities.

  6. THE USE OF EVENT DATA RECORDER (EDR – BLACK BOX

    Directory of Open Access Journals (Sweden)

    Gabriel Nowacki

    2014-03-01

    Full Text Available The paper refers to the registration of road events by a modern device called EDR – black box for all types of the motor vehicles. The device records data concerning vehicle’s technical condition, the way it was driven and RTS. The recorder may be used in private and commercial cars, taxies, buses and trucks. The recorder may serve the purpose of a neutral witness for the police, courts and insurance firms, for which it will facilitate making the reconstruction of the road accidents events and will provide a proof for those who caused them. The device will bring efficient driving, which will significantly contribute to decreasing the number of road accidents and limiting the environmental pollution. In the end in the last year German parliament backed a proposal to the European Commission to put black boxes, which gather information from vehicles involved in accidents, in all the new cars from 2015 on.

  7. Box jellyfish use terrestrial visual cues for navigation.

    Science.gov (United States)

    Garm, Anders; Oskarsson, Magnus; Nilsson, Dan-Eric

    2011-05-10

    Box jellyfish have an impressive set of 24 eyes of four different types, including eyes structurally similar to those of vertebrates and cephalopods [1, 2]. However, the known visual responses are restricted to simple phototaxis, shadow responses, and object avoidance responses [3-8], and it has been a puzzle why they need such a complex set of eyes. Here we report that medusae of the box jellyfish Tripedalia cystophora are capable of visually guided navigation in mangrove swamps using terrestrial structures seen through the water surface. They detect the mangrove canopy by an eye type that is specialized to peer up through the water surface and that is suspended such that it is constantly looking straight up, irrespective of the orientation of the jellyfish. The visual information is used to navigate to the preferred habitat at the edge of mangrove lagoons. Copyright © 2011 Elsevier Ltd. All rights reserved.

  8. A Box-Cox normal model for response times.

    Science.gov (United States)

    Klein Entink, R H; van der Linden, W J; Fox, J-P

    2009-11-01

    The log-transform has been a convenient choice in response time modelling on test items. However, motivated by a dataset of the Medical College Admission Test where the lognormal model violated the normality assumption, the possibilities of the broader class of Box-Cox transformations for response time modelling are investigated. After an introduction and an outline of a broader framework for analysing responses and response times simultaneously, the performance of a Box-Cox normal model for describing response times is investigated using simulation studies and a real data example. A transformation-invariant implementation of the deviance information criterium (DIC) is developed that allows for comparing model fit between models with different transformation parameters. Showing an enhanced description of the shape of the response time distributions, its application in an educational measurement context is discussed at length.

  9. Evaluation process radiological in ternopil region method of box models

    Directory of Open Access Journals (Sweden)

    І.В. Матвєєва

    2006-02-01

    Full Text Available  Results of radionuclides Sr-90 flows analyses in the ecosystem of Kotsubinchiky village of Ternopolskaya oblast were analyzed. The block-scheme of ecosystem and its mathematical model using the box models method were made. It allowed us to evaluate the ways of dose’s loadings formation of internal irradiation for miscellaneous population groups – working people, retirees, children, and also to prognose the dynamic of these loadings during the years after the Chernobyl accident.

  10. Multiple-state quantum Otto engine, 1D box system

    Science.gov (United States)

    Latifah, E.; Purwanto, A.

    2014-03-01

    Quantum heat engines produce work using quantum matter as their working substance. We studied adiabatic and isochoric processes and defined the general force according to quantum system. The processes and general force are used to evaluate a quantum Otto engine based on multiple-state of one dimensional box system and calculate the efficiency. As a result, the efficiency depends on the ratio of initial and final width of system under adiabatic processes.

  11. Multiple-state quantum Otto engine, 1D box system

    Energy Technology Data Exchange (ETDEWEB)

    Latifah, E., E-mail: enylatifah@um.ac.id [Laboratory of Theoretical Physics and Natural Philosophy, Physics Department, Institut Teknologi Sepuluh Nopember, ITS, Surabaya, Indonesia and Physics Department, Malang State University (Indonesia); Purwanto, A. [Laboratory of Theoretical Physics and Natural Philosophy, Physics Department, Institut Teknologi Sepuluh Nopember, ITS, Surabaya (Indonesia)

    2014-03-24

    Quantum heat engines produce work using quantum matter as their working substance. We studied adiabatic and isochoric processes and defined the general force according to quantum system. The processes and general force are used to evaluate a quantum Otto engine based on multiple-state of one dimensional box system and calculate the efficiency. As a result, the efficiency depends on the ratio of initial and final width of system under adiabatic processes.

  12. A Note on Implementing Box-Cox Quantile Regression

    OpenAIRE

    Wilke, Ralf A.; Fitzenberger, Bernd; Zhang, Xuan

    2005-01-01

    The Box-Cox quantile regression model using the two stage method introduced by Chamberlain (1994) and Buchinsky (1995) provides an attractive extension of linear quantile regression techniques. However, a major numerical problem exists when implementing this method which has not been addressed so far in the literature. We suggest a simple solution modifying the estimator slightly. This modification is easy to implement. The modified estimator is still [square root] n-consistent and its asympt...

  13. Packing Infinite Number of Cubes in a Finite Volume Box

    Science.gov (United States)

    Yao, Haishen; Wajngurt, Clara

    2006-01-01

    Packing an infinite number of cubes into a box of finite volume is the focus of this article. The results and diagrams suggest two ways of packing these cubes. Specifically suppose an infinite number of cubes; the side length of the first one is 1; the side length of the second one is 1/2 , and the side length of the nth one is 1/n. Let n approach…

  14. Two-Black Box Concept for Warhead Verification

    Energy Technology Data Exchange (ETDEWEB)

    Bates, Cameron Russell [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Frame, Katherine Chiyoko [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mckigney, Edward Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Smith, Morag Kristin [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-06

    We have created a possible solution to meeting the requirements of certification/authentication while still employing complicated criteria. Technical solutions to protecting information from the host in an inspection environment needs to be assessed by those with specific expertise but, LANL can still study the verification problem. The two-black box framework developed provides another potential solution to the confidence vs. certification paradox.

  15. Box & Jenkins Model Identification:A Comparison of Methodologies

    Directory of Open Access Journals (Sweden)

    Maria Augusta Soares Machado

    2012-12-01

    Full Text Available This paper focuses on a presentation of a comparison of a neuro-fuzzy back propagation network and Forecast automatic model Identification to identify automatically Box & Jenkins non seasonal models.Recently some combinations of neural networks and fuzzy logic technologies have being used to deal with uncertain and subjective problems. It is concluded on the basis of the obtained results that this type of approach is very powerful to be used.

  16. ArduiPod Box: a low-cost and open-source Skinner box using an iPod Touch and an Arduino microcontroller.

    Science.gov (United States)

    Pineño, Oskar

    2014-03-01

    This article introduces the ArduiPod Box, an open-source device built using two main components (i.e., an iPod Touch and an Arduino microcontroller), developed as a low-cost alternative to the standard operant conditioning chamber, or "Skinner box." Because of its affordability, the ArduiPod Box provides an opportunity for educational institutions with small budgets seeking to set up animal laboratories for research and instructional purposes. A pilot experiment is also presented, which shows that the ArduiPod Box, in spite of its extraordinary simplicity, can be effectively used to study animal learning and behavior.

  17. Impact attenuation of protective boxing and taekwondo headgear.

    Science.gov (United States)

    O'Sullivan, David M; Fife, Gabriel P

    2016-11-01

    This study aimed to compare the impact attenuation performance of boxing and taekwondo headgear in terms of peak linear and rotational acceleration. To measure the impact attenuation of headgear, a standardized (American Society for Testing and Materials (ASTM) F-2397) martial arts headgear striker was used to impart impacts to a 50th Percentile Male Hybrid III Crash Test Dummy head and neck complex. Two boxing (Adidas and Greenhill) and two taekwondo (Adidas and Nike) headgear, approved by the Association Internationale de Boxe Amateur and the World Taekwondo Federation (WTF), were selected. Each of the selected headgear was fitted to the Hybrid III head and subsequently subjected to five impacts at the front and side with a maximum impact interim time of 60 seconds by the rotating striker at 8 ± 0.3 m/s. Linear and rotational acceleration were recorded at 10,000 Hz. There were significant interactions of the impact location and brand on the rotational acceleration, F(3,40) = 6.7, p headgear brand F(3,40) = 9.9, p headgear tested failed the ASTM high impact test requirement to reduce the linear acceleration to below a threshold of 150 g. Further development of headgear to reduce impact linear and rotational acceleration magnitudes should be called for by the relevant sport governing bodies and initiated by headgear manufactures.

  18. Analysis and Optimization of Box Girder Bridges in Curved Planform

    Science.gov (United States)

    Chandra Mohan Rao, B. D. V.; Ramana Rao, N. V.

    2012-02-01

    This paper deals with the free vibration analysis and optimization of box girder bridges with curved planform. The finite element analysis of a box girder bridge is carried out and then optimized using ANSYS. The objectives of this paper are (i) minimization of volume subjected to the constraint that the fundamental frequency should be greater than the initial value and (ii) maximization of fundamental frequency with a constraint that total volume of the structure should remain constant. The shape of a box girder bridge is optimized and the results are validated by comparing it with a benchmark problem. The mode shapes of the initial and optimum solutions are also presented. The structural optimization variables used in Case-1 are the design variables (length variables, thickness variables), state variables (fundamental frequency), and the objective function (minimization of volume). The structural optimization variables used in Case-2 are the design variables (length variables, thickness variables), state variables (volume), and the objective function (maximization of fundamental frequency). In Case-1, the volume of the structure has been minimized by 56.4 % and in Case-2, the fundamental frequency of the structure has been increased by 141.9 %, which shows a better performance of the proposed methodology.

  19. T-Box Genes in Drosophila Mesoderm Development.

    Science.gov (United States)

    Reim, I; Frasch, M; Schaub, C

    2017-01-01

    In Drosophila there are eight genes encoding transcription factors of the T-box family, which are known to exert a variety of crucial developmental functions during ectodermal patterning processes, neuronal cell specification, mesodermal tissue development, and the development of extraembryonic tissues. In this review, we focus on the prominent roles of Drosophila T-box genes in mesodermal tissues. First, we describe the contributions of brachyenteron (byn) and optomotor-blind-related-gene-1 (org-1) to the development of the visceral mesoderm. Second, we provide an overview on the functions of the three Dorsocross paralogs (Doc1-3) and the two Tbx20-related paralogs (midline and H15) during Drosophila heart development. Third, we portray the roles of org-1 and midline/H15 in the specification of individual body wall and organ-attached muscles, including the function of org-1 in the transdifferentiation of certain heart-attached muscles during metamorphosis. The functional analysis of these evolutionarily conserved T-box genes, along with their interactions with other types of transcription factors and various signaling pathways, has provided key insights into the regulation of Drosophila visceral mesoderm, muscle, and heart development. © 2017 Elsevier Inc. All rights reserved.

  20. The development of a reliable amateur boxing performance analysis template.

    Science.gov (United States)

    Thomson, Edward; Lamb, Kevin; Nicholas, Ceri

    2013-01-01

    The aim of this study was to devise a valid performance analysis system for the assessment of the movement characteristics associated with competitive amateur boxing and assess its reliability using analysts of varying experience of the sport and performance analysis. Key performance indicators to characterise the demands of an amateur contest (offensive, defensive and feinting) were developed and notated using a computerised notational analysis system. Data were subjected to intra- and inter-observer reliability assessment using median sign tests and calculating the proportion of agreement within predetermined limits of error. For all performance indicators, intra-observer reliability revealed non-significant differences between observations (P > 0.05) and high agreement was established (80-100%) regardless of whether exact or the reference value of ±1 was applied. Inter-observer reliability was less impressive for both analysts (amateur boxer and experienced analyst), with the proportion of agreement ranging from 33-100%. Nonetheless, there was no systematic bias between observations for any indicator (P > 0.05), and the proportion of agreement within the reference range (±1) was 100%. A reliable performance analysis template has been developed for the assessment of amateur boxing performance and is available for use by researchers, coaches and athletes to classify and quantify the movement characteristics of amateur boxing.

  1. An Introduction to Plum Blossom Boxing: History, Culture and Practice

    Directory of Open Access Journals (Sweden)

    Guodong Zhang

    2012-07-01

    Full Text Available Meihuaquan (“Plum Blossom Fist [Boxing]” has traditionally been practiced as vernacular (folk art practiced among the Han ethnic group residing in the Shandong, Henan and Hebei Provinces of China. Historical documentation dates Plum Blossom Boxing to the seventeenth century. The classic Chinese novel, Shuǐhǔ Zhuàn (Marsh Chronicles recounts the martial exploits of Shandong’s twelfth century outlaw heroes who may have been Mei Boxers, also. Thus, for perhaps a millennium, the region has been noted for vernacular martial arts and social banditry. The region’s rampant lawlessness promoted highly-developed martial prowess among both lawbreakers and those who were required to protect themselves against the brigands. Cultural, economic, and environmental factors in the region gave rise to heterodox political and religious beliefs that frequently served as a catalyst for martial sects, most notably the “Boxers” who at the turn of the twentieth century, came into conflict with the imperial government. These factors laid the groundwork for the “character traits” of the art while Taoism, the Five Elements theory, and a concept of predictable change shaped Plum Boxing’s strategic and mechanical principles. In the past decade, there have been efforts to globalize this vernacular martial art. Rather than driving Plum Boxing to extinction it is likely that the folk and the “larger than local” will co-exist.

  2. The ring nerve of the box jellyfish Tripedalia cystophora.

    Science.gov (United States)

    Garm, A; Poussart, Y; Parkefelt, L; Ekström, P; Nilsson, D-E

    2007-07-01

    Box jellyfish have the most elaborate sensory system and behavioural repertoire of all cnidarians. Sensory input largely comes from 24 eyes situated on four club-shaped sensory structures, the rhopalia, and behaviour includes obstacle avoidance, light shaft attractance and mating. To process the sensory input and convert it into the appropriate behaviour, the box jellyfish have a central nervous system (CNS) but this is still poorly understood. The CNS has two major components: the rhopalial nervous system and the ring nerve. The rhopalial nervous system is situated within the rhopalia in close connection with the eyes, whereas the ring nerve encircles the bell. We describe the morphology of the ring nerve of the box jellyfish Tripedalia cystophora as ascertained by normal histological techniques, immunohistochemistry and transmission electron microscopy. By light microscopy, we have estimated the number of cells in the ring nerve by counting their nuclei. In cross sections at the ultrastructural level, the ring nerve appears to have three types of neurites: (1) small "normal"-looking neurites, (2) medium-sized neurites almost completely filled by electron-lucent vacuoles and (3) giant neurites. In general, only one giant neurite is seen on each section; this type displays the most synapses. Epithelial cells divide the ring nerve into compartments, each having a tendency to contain neurites of similar morphology. The number and arrangement of the compartments vary along the length of the ring nerve.

  3. Vehicle Plate Detection in Car Black Box Video

    Directory of Open Access Journals (Sweden)

    Dongjin Park

    2017-01-01

    Full Text Available Internet services that share vehicle black box videos need a way to obfuscate license plates in uploaded videos because of privacy issues. Thus, plate detection is one of the critical functions that such services rely on. Even though various types of detection methods are available, they are not suitable for black box videos because no assumption about size, number of plates, and lighting conditions can be made. We propose a method to detect Korean vehicle plates from black box videos. It works in two stages: the first stage aims to locate a set of candidate plate regions and the second stage identifies only actual plates from candidates by using a support vector machine classifier. The first stage consists of five sequential substeps. At first, it produces candidate regions by combining single character areas and then eliminates candidate regions that fail to meet plate conditions through the remaining substeps. For the second stage, we propose a feature vector that captures the characteristics of plates in texture and color. For performance evaluation, we compiled our dataset which contains 2,627 positive and negative images. The evaluation results show that the proposed method improves accuracy and sensitivity by at least 5% and is 30 times faster compared with an existing method.

  4. Genome-wide identification and characterization of MADS-box family genes related to organ development and stress resistance in Brassica rapa.

    Science.gov (United States)

    Saha, Gopal; Park, Jong-In; Jung, Hee-Jeong; Ahmed, Nasar Uddin; Kayum, Md Abdul; Chung, Mi-Young; Hur, Yoonkang; Cho, Yong-Gu; Watanabe, Masao; Nou, Ill-Sup

    2015-03-14

    MADS-box transcription factors (TFs) are important in floral organ specification as well as several other aspects of plant growth and development. Studies on stress resistance-related functions of MADS-box genes are very limited and no such functional studies in Brassica rapa have been reported. To gain insight into this gene family and to elucidate their roles in organ development and stress resistance, we performed genome-wide identification, characterization and expression analysis of MADS-box genes in B. rapa. Whole-genome survey of B. rapa revealed 167 MADS-box genes, which were categorized into type I (Mα, Mβ and Mγ) and type II (MIKC(c) and MIKC*) based on phylogeny, protein motif structure and exon-intron organization. Expression analysis of 89 MIKC(c) and 11 MIKC* genes was then carried out. In addition to those with floral and vegetative tissue expression, we identified MADS-box genes with constitutive expression patterns at different stages of flower development. More importantly, from a low temperature-treated whole-genome microarray data set, 19 BrMADS genes were found to show variable transcript abundance in two contrasting inbred lines of B. rapa. Among these, 13 BrMADS genes were further validated and their differential expression was monitored in response to cold stress in the same two lines via qPCR expression analysis. Additionally, the set of 19 BrMADS genes was analyzed under drought and salt stress, and 8 and 6 genes were found to be induced by drought and salt, respectively. The extensive annotation and transcriptome profiling reported in this study will be useful for understanding the involvement of MADS-box genes in stress resistance in addition to their growth and developmental functions, which ultimately provides the basis for functional characterization and exploitation of the candidate genes for genetic engineering of B. rapa.

  5. Disposable Bioreactors for Plant Micropropagation and Mass Plant Cell Culture

    Science.gov (United States)

    Ducos, Jean-Paul; Terrier, Bénédicte; Courtois, Didier

    Different types of bioreactors are used at Nestlé R&D Centre - Tours for mass propagation of selected plant varieties by somatic embryogenesis and for large scale culture of plants cells to produce metabolites or recombinant proteins. Recent studies have been directed to cut down the production costs of these two processes by developing disposable cell culture systems. Vegetative propagation of elite plant varieties is achieved through somatic embryogenesis in liquid medium. A pilot scale process has recently been set up for the industrial propagation of Coffea canephora (Robusta coffee). The current production capacity is 3.0 million embryos per year. The pre-germination of the embryos was previously conducted by temporary immersion in liquid medium in 10-L glass bioreactors. An improved process has been developed using a 10-L disposable bioreactor consisting of a bag containing a rigid plastic box ('Box-in-Bag' bioreactor), insuring, amongst other advantages, a higher light transmittance to the biomass due to its horizontal design. For large scale cell culture, two novel flexible plastic-based disposable bioreactors have been developed from 10 to 100 L working volumes, validated with several plant species ('Wave and Undertow' and 'Slug Bubble' bioreactors). The advantages and the limits of these new types of bioreactor are discussed, based mainly on our own experience on coffee somatic embryogenesis and mass cell culture of soya and tobacco.

  6. SlDEAD31, a Putative DEAD-Box RNA Helicase Gene, Regulates Salt and Drought Tolerance and Stress-Related Genes in Tomato.

    Directory of Open Access Journals (Sweden)

    Mingku Zhu

    Full Text Available The DEAD-box RNA helicases are involved in almost every aspect of RNA metabolism, associated with diverse cellular functions including plant growth and development, and their importance in response to biotic and abiotic stresses is only beginning to emerge. However, none of DEAD-box genes was well characterized in tomato so far. In this study, we reported on the identification and characterization of two putative DEAD-box RNA helicase genes, SlDEAD30 and SlDEAD31 from tomato, which were classified into stress-related DEAD-box proteins by phylogenetic analysis. Expression analysis indicated that SlDEAD30 was highly expressed in roots and mature leaves, while SlDEAD31 was constantly expressed in various tissues. Furthermore, the expression of both genes was induced mainly in roots under NaCl stress, and SlDEAD31 mRNA was also increased by heat, cold, and dehydration. In stress assays, transgenic tomato plants overexpressing SlDEAD31 exhibited dramatically enhanced salt tolerance and slightly improved drought resistance, which were simultaneously demonstrated by significantly enhanced expression of multiple biotic and abiotic stress-related genes, higher survival rate, relative water content (RWC and chlorophyll content, and lower water loss rate and malondialdehyde (MDA production compared to wild-type plants. Collectively, these results provide a preliminary characterization of SlDEAD30 and SlDEAD31 genes in tomato, and suggest that stress-responsive SlDEAD31 is essential for salt and drought tolerance and stress-related gene regulation in plants.

  7. The regulatory mechanism of fruit ripening revealed by analyses of direct targets of the tomato MADS-box transcription factor RIPENING INHIBITOR

    OpenAIRE

    Fujisawa, Masaki; Ito, Yasuhiro

    2013-01-01

    The developmental process of ripening is unique to fleshy fruits and a key factor in fruit quality. The tomato (Solanum lycopersicum) MADS-box transcription factor RIPENING INHIBITOR (RIN), one of the earliest-acting ripening regulators, is required for broad aspects of ripening, including ethylene-dependent and -independent pathways. However, our knowledge of direct RIN target genes has been limited, considering the broad effects of RIN on ripening. In a recent work published in The Plant Ce...

  8. Structural strength analysis and fatigue life prediction of traction converter box in high-speed EMU

    Science.gov (United States)

    Tan, Qin; Li, Qiang

    2017-01-01

    The method of building the FEA model of traction converter box in high-speed EMU and analyzing the static strength and fatigue strength of traction converter box based on IEC 61373-2010 and EN 12663 standards is presented in this paper. The load-stress correlation coefficients of weak points is obtained by FEA model, applied to transfer the load history of traction converter box to stress history of each point. The fatigue damage is calculated based on Miner's rule and the fatigue life of traction converter box is predicted. According to study, the structural strength of traction converter box meets design requirements.

  9. Power box: an energy workshop in ten lessons; Power Box: ein Energie-Workshop in 10 Lektionen

    Energy Technology Data Exchange (ETDEWEB)

    Gasser, S.; Bush, E. [Amstein + Walthert AG, Zurich (Switzerland); Lainsecq, M. de; Humm, O. [Oerlikon Journalisten AG, Zurich (Switzerland)

    1995-12-31

    The teaching medium Power Box was created within the framework of the impulse program RAVEL by energy experts working together with teachers. It is oriented primarily towards non-technical groups and is specially suitable for business schools, technical colleges, high schools and the highest level of intermediate schools. This teaching medium summarises the current knowledge of experts for rational use of energy compactly for the teacher. figs., tabs., refs.

  10. Evolution and Classification of the T-Box Transcription Factor Family.

    Science.gov (United States)

    Sebé-Pedrós, A; Ruiz-Trillo, I

    2017-01-01

    T-box proteins are key developmental transcription factors in Metazoa. Until recently they were thought to be animal specific and many T-box classes were considered bilaterian specific. Recent genome data from both early-branching animals and their closest unicellular relatives have radically changed this scenario. Thus, we now know that T-box genes originated in premetazoans, being present in the genomes of some extant early-branching fungi and unicellular holozoans. Here, we update the evolutionary classification of T-box families and review the evolution of T-box function in early-branching animals (sponges, ctenophores, placozoans, and cnidarians) and nonmodel bilaterians. We show that concomitant with the origin of Metazoa, the T-box family radiated into the major known T-box classes. On the other hand, while functional studies are still missing for many T-box classes, the emerging picture is that T-box genes have key roles in multiple aspects of development and in adult terminal cell-type differentiation in different animal lineages. A paradigmatic example is that of Brachyury, the founding member of the T-box family, for which several studies indicate a widely conserved role in regulating cell motility in different animal lineages and probably even before the advent of animal multicellularity. Overall, we here review the evolutionary history of T-box genes from holozoans to animals and discuss both their functional diversity and conservation. © 2017 Elsevier Inc. All rights reserved.

  11. Insights into the quality of DnaA boxes and their cooperativity

    DEFF Research Database (Denmark)

    Hansen, Flemming G.; Christensen, Bjarke Bak; Nielsen, Christina Bang

    2006-01-01

    Plasmids carrying the mioC promoter region with its two DnaA boxes are as efficient in titration of DnaA protein as plasmids carrying a replicationinactivated oriC region with its five DnaA boxes. The two DnaA boxes upstream of the mioC promoter were mutated in various ways to study the cooperati......Plasmids carrying the mioC promoter region with its two DnaA boxes are as efficient in titration of DnaA protein as plasmids carrying a replicationinactivated oriC region with its five DnaA boxes. The two DnaA boxes upstream of the mioC promoter were mutated in various ways to study...... the cooperativity between the DnaA boxes, and to study in vivo the in vitrodefined 9mer DnaA box consensus sequence TTA/TTNCACA). The quality and cooperativity of the DnaA oxes were determined in two complementary ways: as titration of DnaA protein leading to derepression of the dnaA promoter, and as repression...... of the mioC promoter caused by the DnaA protein binding to the DnaA boxes. Titration of DnaA protein correlated with repression of the mioC promoter. The level of titration and repression with the normal promoter-proximal box (TTTTCCACA) depends strongly on the presence and the quality of a DnaA box...

  12. Occupancy rates and nesting success of European storm-petrels breeding inside artificial nest-boxes

    Directory of Open Access Journals (Sweden)

    Ana de León

    2003-07-01

    Full Text Available We report on occupancy rates and nesting success of European storm-petrels Hydrobates pelagicus breeding in artificial nest-boxes for five years. Plastic nest-boxes were installed inside two natural caves on the island of Benidorm (western Mediterranean, where breeding colonies of the species occur. The location of nest-boxes was (a over exposed natural nests or (b at sites without nests, but usually close to them. Nest-boxes were visited during the breeding season following installation, when only nest-boxes over old nests were occupied. Occupancy rates in both types of nest-box increased gradually year after year, reaching 29% in the fifth year. Nesting success of pairs breeding inside boxes was higher than nesting success of pairs breeding at natural sites.

  13. Rooting of cuttings of vanilla plant (Orchidaceae)

    OpenAIRE

    Aparecida Gomes de Araujo; José Maria Moreira Dias; Flávio Pereira Silva; Moacir Pasqual; Maria das Dôres David Silva

    2009-01-01

    The vanilla plant (Vanilla planifolia) could have a higher commercial production but there are problems in the efficiency of propagation. The present work was conducted with the aim of studying the effect of different substrates, in the adventitious rooting of cuttings taken at five heights in the plant stem. The cuttings were 20cm long and had two buds and one leaf and were planted in: 1) Liquid medium formed by Clark’s nutrient added of 2.5mg L-1 of IBA placed in plastic foam box with a cap...

  14. Genomic organization, phylogenetic and expression analysis of the B-BOX gene family in tomato

    Directory of Open Access Journals (Sweden)

    Zhuan Nan Chu

    2016-10-01

    Full Text Available The B-BOX (BBX proteins encode a class of zinc-finger transcription factors possessing one or two B-BOX domains and in some cases an additional CCT (CO, CO-like, and TOC1 motif, which play important roles in regulating plant growth, development and stress response. Nevertheless, no systematic study of BBX genes has been undertaken in tomato (Solanum lycopersicum. Here we present the results of a genome-wide analysis of the 29 BBX genes in this important vegetable species. Their structures, conserved domains, phylogenetic relationships, subcellular localizations, and promoter cis-regulatory elements were analyzed; their tissue expression profiles and expression patterns under various hormones and stress treatments were also investigated in detail. Tomato BBX genes can be divided into five subfamilies, and thirteen of them were found to be segmentally duplicated. Real-time quantitative PCR analysis showed that most BBX genes exhibited different temporal and spatial expression patterns, such as SlBBX24, which was constitutively expressed with high abundance in nearly all tissues studied, and eight genes (SlBBX4, 5, 6, 11, 16, 18, 19, and 22 showed relatively higher expression levels in vegetative tissues and non-ripening fruits. The expression of most BBX genes can be induced by drought, polyethylene glycol-6000 or heat stress. Some BBX genes were induced strongly by phytohormones such as abscisic acid, gibberellic acid or ethephon. The majority of tomato BBX proteins was predicted to be located in nuclei, and the transient expression assay using Arabidopsis mesophyll protoplasts demonstrated that all the seven BBX members tested (SlBBX5, 7, 15, 17, 20, 22 and 24 were localized in nucleus. Our analysis of tomato BBX genes on the genome scale would provide valuable information for future functional characterization of specific genes in this family.

  15. Box-Behnken design for investigation of microwave-assisted extraction of patchouli oil

    Science.gov (United States)

    Kusuma, Heri Septya; Mahfud, Mahfud

    2015-12-01

    Microwave-assisted extraction (MAE) technique was employed to extract the essential oil from patchouli (Pogostemon cablin). The optimal conditions for microwave-assisted extraction of patchouli oil were determined by response surface methodology. A Box-Behnken design (BBD) was applied to evaluate the effects of three independent variables (microwave power (A: 400-800 W), plant material to solvent ratio (B: 0.10-0.20 g mL-1) and extraction time (C: 20-60 min)) on the extraction yield of patchouli oil. The correlation analysis of the mathematical-regression model indicated that quadratic polynomial model could be employed to optimize the microwave extraction of patchouli oil. The optimal extraction conditions of patchouli oil was microwave power 634.024 W, plant material to solvent ratio 0.147648 g ml-1 and extraction time 51.6174 min. The maximum patchouli oil yield was 2.80516% under these optimal conditions. Under the extraction condition, the experimental values agreed with the predicted results by analysis of variance. It indicated high fitness of the model used and the success of response surface methodology for optimizing and reflect the expected extraction condition.

  16. Simulation of the Predictive Control Algorithm for Container Crane Operation using Matlab Fuzzy Logic Tool Box

    Science.gov (United States)

    Richardson, Albert O.

    1997-01-01

    This research has investigated the use of fuzzy logic, via the Matlab Fuzzy Logic Tool Box, to design optimized controller systems. The engineering system for which the controller was designed and simulate was the container crane. The fuzzy logic algorithm that was investigated was the 'predictive control' algorithm. The plant dynamics of the container crane is representative of many important systems including robotic arm movements. The container crane that was investigated had a trolley motor and hoist motor. Total distance to be traveled by the trolley was 15 meters. The obstruction height was 5 meters. Crane height was 17.8 meters. Trolley mass was 7500 kilograms. Load mass was 6450 kilograms. Maximum trolley and rope velocities were 1.25 meters per sec. and 0.3 meters per sec., respectively. The fuzzy logic approach allowed the inclusion, in the controller model, of performance indices that are more effectively defined in linguistic terms. These include 'safety' and 'cargo swaying'. Two fuzzy inference systems were implemented using the Matlab simulation package, namely the Mamdani system (which relates fuzzy input variables to fuzzy output variables), and the Sugeno system (which relates fuzzy input variables to crisp output variable). It is found that the Sugeno FIS is better suited to including aspects of those plant dynamics whose mathematical relationships can be determined.

  17. Overexpression of a novel MADS-box gene SlFYFL delays senescence, fruit ripening and abscission in tomato

    Science.gov (United States)

    Xie, Qiaoli; Hu, Zongli; Zhu, Zhiguo; Dong, Tingting; Zhao, Zhiping; Cui, Baolu; Chen, Guoping

    2014-03-01

    MADS-domain proteins are important transcription factors involved in many biological processes of plants. In our study, a tomato MADS-box gene, SlFYFL, was isolated. SlFYFL is expressed in all tissues of tomato and significantly higher in mature leave, fruit of different stages, AZ (abscission zone) and sepal. Delayed leaf senescence and fruit ripening, increased storability and longer sepals were observed in 35S:FYFL tomato. The accumulation of carotenoid was reduced, and ethylene content, ethylene biosynthetic and responsive genes were down-regulated in 35S:FYFL fruits. Abscission zone (AZ) did not form normally and abscission zone development related genes were declined in AZs of 35S:FYFL plants. Yeast two-hybrid assay revealed that SlFYFL protein could interact with SlMADS-RIN, SlMADS1 and SlJOINTLESS, respectively. These results suggest that overexpression of SlFYFL regulate fruit ripening and development of AZ via interactions with the ripening and abscission zone-related MADS box proteins.

  18. Chloroplast- or Mitochondria-Targeted DEAD-Box RNA Helicases Play Essential Roles in Organellar RNA Metabolism and Abiotic Stress Responses

    Directory of Open Access Journals (Sweden)

    Ghazala Nawaz

    2017-05-01

    Full Text Available The yields and productivity of crops are greatly diminished by various abiotic stresses, including drought, cold, heat, and high salinity. Chloroplasts and mitochondria are cellular organelles that can sense diverse environmental stimuli and alter gene expression to cope with adverse environmental stresses. Organellar gene expression is mainly regulated at posttranscriptional levels, including RNA processing, intron splicing, RNA editing, RNA turnover, and translational control, during which a variety of nucleus-encoded RNA-binding proteins (RBPs are targeted to chloroplasts or mitochondria where they play essential roles in organellar RNA metabolism. DEAD-box RNA helicases (RHs are enzymes that can alter RNA structures and affect RNA metabolism in all living organisms. Although a number of DEAD-box RHs have been found to play important roles in RNA metabolism in the nucleus and cytoplasm, our understanding on the roles of DEAD-box RHs in the regulation of RNA metabolism in chloroplasts and mitochondria is only at the beginning. Considering that organellar RNA metabolism and gene expression are tightly regulated by anterograde signaling from the nucleus, it is imperative to determine the functions of nucleus-encoded organellar RBPs. In this review, we summarize the emerging roles of nucleus-encoded chloroplast- or mitochondria-targeted DEAD-box RHs in organellar RNA metabolism and plant response to diverse abiotic stresses.

  19. Chloroplast- or Mitochondria-Targeted DEAD-Box RNA Helicases Play Essential Roles in Organellar RNA Metabolism and Abiotic Stress Responses

    Science.gov (United States)

    Nawaz, Ghazala; Kang, Hunseung

    2017-01-01

    The yields and productivity of crops are greatly diminished by various abiotic stresses, including drought, cold, heat, and high salinity. Chloroplasts and mitochondria are cellular organelles that can sense diverse environmental stimuli and alter gene expression to cope with adverse environmental stresses. Organellar gene expression is mainly regulated at posttranscriptional levels, including RNA processing, intron splicing, RNA editing, RNA turnover, and translational control, during which a variety of nucleus-encoded RNA-binding proteins (RBPs) are targeted to chloroplasts or mitochondria where they play essential roles in organellar RNA metabolism. DEAD-box RNA helicases (RHs) are enzymes that can alter RNA structures and affect RNA metabolism in all living organisms. Although a number of DEAD-box RHs have been found to play important roles in RNA metabolism in the nucleus and cytoplasm, our understanding on the roles of DEAD-box RHs in the regulation of RNA metabolism in chloroplasts and mitochondria is only at the beginning. Considering that organellar RNA metabolism and gene expression are tightly regulated by anterograde signaling from the nucleus, it is imperative to determine the functions of nucleus-encoded organellar RBPs. In this review, we summarize the emerging roles of nucleus-encoded chloroplast- or mitochondria-targeted DEAD-box RHs in organellar RNA metabolism and plant response to diverse abiotic stresses. PMID:28596782

  20. Dose and time dependence of box jellyfish antivenom.

    Science.gov (United States)

    Andreosso, Athena; Smout, Michael J; Seymour, Jamie E

    2014-01-01

    The effectiveness of the currently available box jellyfish (Chironex fleckeri) antivenom has been subject of debate for many years. To assess whether the box jellyfish antivenom has the ability to attenuate venom-induced damage at cellular level, the present study analyzed the dose and time dependence of the antivenom in a cell-based assay. Different doses of antivenom were added to venom and subsequently administered to cells and the cell index was measured using xCelligence Technology (ACEA Biosciences). Similarly, antivenom and venom were incubated over different time periods and cell survival measured as stated above. For both experiments, the cell index was plotted as a measure of cell survival against the dose or incubation time and significance was determined with the use of a one-way ANOVA with a LSD post hoc test. Increasing concentrations of antivenom significantly augmented cell survival, with a concentration of approximately five times the currently recommended dose for human envenomation, causing the first significant increase in cell survival compared venom alone. Further, cell survival improved with increasing incubation time of venom and antivenom prior to addition to the cells, indicating that box jellyfish antivenom requires approximately 70 minutes to neutralize C. fleckeri venom. The presented results suggest that the currently recommended dose of antivenom requires adjustment, and more importantly, a human trial to test the effects of higher concentrations is also necessary. Further, antivenom has delayed neutralizing effects (i.e. after 70 minutes) which underlines the eminence of immediate and prolonged cardiopulmonary resuscitation in victims suffering from a C. fleckeri venom-induced cardiovascular collapse.

  1. Transcriptome and venom proteome of the box jellyfish Chironex fleckeri.

    Science.gov (United States)

    Brinkman, Diane L; Jia, Xinying; Potriquet, Jeremy; Kumar, Dhirendra; Dash, Debasis; Kvaskoff, David; Mulvenna, Jason

    2015-05-27

    The box jellyfish, Chironex fleckeri, is the largest and most dangerous cubozoan jellyfish to humans. It produces potent and rapid-acting venom and its sting causes severe localized and systemic effects that are potentially life-threatening. In this study, a combined transcriptomic and proteomic approach was used to identify C. fleckeri proteins that elicit toxic effects in envenoming. More than 40,000,000 Illumina reads were used to de novo assemble ∼ 34,000 contiguous cDNA sequences and ∼ 20,000 proteins were predicted based on homology searches, protein motifs, gene ontology and biological pathway mapping. More than 170 potential toxin proteins were identified from the transcriptome on the basis of homology to known toxins in publicly available sequence databases. MS/MS analysis of C. fleckeri venom identified over 250 proteins, including a subset of the toxins predicted from analysis of the transcriptome. Potential toxins identified using MS/MS included metalloproteinases, an alpha-macroglobulin domain containing protein, two CRISP proteins and a turripeptide-like protease inhibitor. Nine novel examples of a taxonomically restricted family of potent cnidarian pore-forming toxins were also identified. Members of this toxin family are potently haemolytic and cause pain, inflammation, dermonecrosis, cardiovascular collapse and death in experimental animals, suggesting that these toxins are responsible for many of the symptoms of C. fleckeri envenomation. This study provides the first overview of a box jellyfish transcriptome which, coupled with venom proteomics data, enhances our current understanding of box jellyfish venom composition and the molecular structure and function of cnidarian toxins. The generated data represent a useful resource to guide future comparative studies, novel protein/peptide discovery and the development of more effective treatments for jellyfish stings in humans. (Length: 300).

  2. Implementation of qq-production in the POWHEG-BOX

    Energy Technology Data Exchange (ETDEWEB)

    Hangst, Christian; Muehlleitner, Margarete; Popenda, Eva [KIT - Institut fuer Theoretische Physik (Germany); Kraemer, Michael [RWTH Aachen Univ. (Germany). Inst. fuer Theoretische Teilchenphysik und Kosmologie; Spira, Michael [Paul Scherrer Institut - Theory Group LTP (Switzerland)

    2012-07-01

    Precise predictions for the production of SUSY-particles at the LHC in the framework of the MSSM make the combination of fixed-order NLO-calculations and parton-showers indispensable. The POWHEG-method is one of several existing possibilities to avoid in this step of the simulation the occurrence of the so called double-counting problem. I present the implementation of qq-production into the existing program POWHEG-BOX, which provides the process-independent steps of this method automatically.

  3. Analysis of the COS/NUV Extraction Box Heights

    Science.gov (United States)

    Synder, Elaine M.; Sonnentrucker, Paule

    2017-08-01

    We present a diagnostic test of the extraction box heights (EBHs) used when extracting NUV spectroscopic data. This study was motivated by a discrepancy between the EBH used by the COS Exposure Time Calculator during observation planning (8 pixels) and the COS calibration pipeline (CALCOS) during the creation of the final spectra (57 pixels). In this Instrument Science Report, we study the effects of decreasing the EBH on the net counts and signal-to-noise ratio for CALCOS-reduced spectra of many different targets. We also provide detailed instructions for users who wish to perform a custom extraction for their data

  4. A Matrix PRNG with S-Box Output Filtering

    Directory of Open Access Journals (Sweden)

    Rafael Alvarez

    2014-01-01

    Full Text Available We describe a modification to a previously published pseudorandom number generator improving security while maintaining high performance. The proposed generator is based on the powers of a word-packed block upper triangular matrix and it is designed to be fast and easy to implement in software since it mainly involves bitwise operations between machine registers and, in our tests, it presents excellent security and statistical characteristics. The modifications include a new, key-derived s-box based nonlinear output filter and improved seeding and extraction mechanisms. This output filter can also be applied to other generators.

  5. Assessing household health expenditure with Box-Cox censoring models.

    Science.gov (United States)

    Chaze, Jean-Paul

    2005-09-01

    In order to assess the combined presence of zero expenditures and a heavily skewed distribution of positive expenditures, the Box-Cox transformation with location parameter is used to define a set of models generalising the standard Tobit, Heckman selection and double-hurdle models. Extended flexibility with respect to previous specifications is introduced, notably regarding negative transformation parameters, which may prove necessary for medical expenditures, and corner-solution outcomes. An illustration is provided by the analysis of household health expenditure in Switzerland. Copyright (c) 2005 John Wiley & Sons, Ltd.

  6. Introduction to game physics with Box2D

    CERN Document Server

    Parberry, Ian

    2013-01-01

    Written by a pioneer of game development in academia, Introduction to Game Physics with Box2D covers the theory and practice of 2D game physics in a relaxed and entertaining yet instructional style. It offers a cohesive treatment of the topics and code involved in programming the physics for 2D video games. Focusing on writing elementary game physics code, the first half of the book helps you grasp the challenges of programming game physics from scratch, without libraries or outside help. It examines the mathematical foundation of game physics and illustrates how it is applied in practice thro

  7. How to handle a Huygens' box inside an enclosure

    DEFF Research Database (Denmark)

    Sørensen, Morten; Bonev, Ivan Bonev; Franek, Ondrej

    2013-01-01

    It has been suggested that it is possible to replace printed circuit boards with a Huygens' box (HB) representation obtained from a near-field scan in simulation of far-fields from an apparatus. However, the surface equivalence theorem requires that the environment outside HB is the same in the n...... caused by violating the surface equivalence theorem can be lower than 2 dB. It is also demonstrated that if the printed circuit board is galvanically connected to the enclosure, the near-field scan must be performed under same conditions....

  8. Standard Waste Box Lid Screw Removal Option Testing

    Energy Technology Data Exchange (ETDEWEB)

    Anast, Kurt Roy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-11

    This report provides results from test work conducted to resolve the removal of screws securing the standard waste box (SWB) lids that hold the remediated nitrate salt (RNS) drums. The test work evaluated equipment and process alternatives for removing the 42 screws that hold the SWB lid in place. The screws were secured with a red Loctite thread locker that makes removal very difficult because the rivets that the screw threads into would slip before the screw could be freed from the rivet, making it impossible to remove the screw and therefore the SWB lid.

  9. Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

    Science.gov (United States)

    Doyle, Monica; ONeil, Daniel A.; Christensen, Carissa B.

    2005-01-01

    The Advanced Technology Lifecycle Analysis System (ATLAS) is a decision support tool designed to aid program managers and strategic planners in determining how to invest technology research and development dollars. It is an Excel-based modeling package that allows a user to build complex space architectures and evaluate the impact of various technology choices. ATLAS contains system models, cost and operations models, a campaign timeline and a centralized technology database. Technology data for all system models is drawn from a common database, the ATLAS Technology Tool Box (TTB). The TTB provides a comprehensive, architecture-independent technology database that is keyed to current and future timeframes.

  10. Optimized design of LED plant lamp

    Science.gov (United States)

    Chen, Jian-sheng; Cai, Ruhai; Zhao, Yunyun; Zhao, Fuli; Yang, Bowen

    2014-12-01

    In order to fabricate the optimized LED plant lamp we demonstrated an optical spectral exploration. According to the mechanism of higher plant photosynthesis process and the spectral analysis we demonstrate an optical design of the LED plant lamp. Furthermore we built two kins of prototypes of the LED plant lamps which are suitable for the photosynthesis of higher green vegetables. Based on the simulation of the lamp box of the different alignment of the plants we carried out the growing experiment of green vegetable and obtain the optimized light illumination as well as the spectral profile. The results show that only blue and red light are efficient for the green leave vegetables. Our work is undoubtedly helpful for the LED plant lamping design and manufacture.

  11. Evolution of the F-Box Gene Family in Euarchontoglires: Gene Number Variation and Selection Patterns

    Science.gov (United States)

    Wang, Ailan; Fu, Mingchuan; Jiang, Xiaoqian; Mao, Yuanhui; Li, Xiangchen; Tao, Shiheng

    2014-01-01

    F-box proteins are substrate adaptors used by the SKP1–CUL1–F-box protein (SCF) complex, a type of E3 ubiquitin ligase complex in the ubiquitin proteasome system (UPS). SCF-mediated ubiquitylation regulates proteolysis of hundreds of cellular proteins involved in key signaling and disease systems. However, our knowledge of the evolution of the F-box gene family in Euarchontoglires is limited. In the present study, 559 F-box genes and nine related pseudogenes were identified in eight genomes. Lineage-specific gene gain and loss events occurred during the evolution of Euarchontoglires, resulting in varying F-box gene numbers ranging from 66 to 81 among the eight species. Both tandem duplication and retrotransposition were found to have contributed to the increase of F-box gene number, whereas mutation in the F-box domain was the main mechanism responsible for reduction in the number of F-box genes, resulting in a balance of expansion and contraction in the F-box gene family. Thus, the Euarchontoglire F-box gene family evolved under a birth-and-death model. Signatures of positive selection were detected in substrate-recognizing domains of multiple F-box proteins, and adaptive changes played a role in evolution of the Euarchontoglire F-box gene family. In addition, single nucleotide polymorphism (SNP) distributions were found to be highly non-random among different regions of F-box genes in 1092 human individuals, with domain regions having a significantly lower number of non-synonymous SNPs. PMID:24727786

  12. Tortoiseshell or Polymer? Spectroscopic Analysis to Redefine a Purported Tortoiseshell Box with Gold Decorations as a Plastic Box with Brass.

    Science.gov (United States)

    Pereira, António; Caldeira, Ana Teresa; Maduro, Belmira; Vandenabeele, Peter; Candeias, António

    2016-01-01

    The study and preservation of museum collections requires complete knowledge and understanding of constituent materials that can be natural, synthetic, or semi-synthetic polymers. In former times, objects were incorporated in museum collections and classified solely by their appearance. New studies, prompted by severe degradation processes or conservation-restoration actions, help shed light on the materiality of objects that can contradict the original information or assumptions. The selected case study presented here is of a box dating from the beginning of the 20th century that belongs to the Portuguese National Ancient Art Museum. Museum curators classified it as a tortoiseshell box decorated with gold applications solely on the basis of visual inspection and the information provided by the donor. This box has visible signs of degradation with white veils, initially assumed to be the result of biological degradation of a proteinaceous matrix. This paper presents the methodological rationale behind this study and proposes a totally non-invasive methodology for the identification of polymeric materials in museum artifacts. The analysis of surface leachates using (1)H and (13)C nuclear magnetic resonance (NMR) complemented by in situ attenuated total reflection infrared spectroscopy (ATR FT-IR) allowed for full characterization of the object s substratum. The NMR technique unequivocally identified a great number of additives and ATR FT-IR provided information about the polymer structure and while also confirming the presence of additives. The pressure applied during ATR FT-IR spectroscopy did not cause any physical change in the structure of the material at the level of the surface (e.g., color, texture, brightness, etc.). In this study, variable pressure scanning electron microscopy (VP-SEM-EDS) was also used to obtain the elemental composition of the metallic decorations. Additionally, microbiologic and enzymatic assays were performed in order to identify the

  13. Visual control of steering in the box jellyfish Tripedalia cystophora.

    Science.gov (United States)

    Petie, Ronald; Garm, Anders; Nilsson, Dan-Eric

    2011-09-01

    Box jellyfish carry an elaborate visual system consisting of 24 eyes, which they use for driving a number of behaviours. However, it is not known how visual input controls the swimming behaviour. In this study we exposed the Caribbean box jellyfish Tripedalia cystophora to simple visual stimuli and recorded changes in their swimming behaviour. Animals were tethered in a small experimental chamber, where we could control lighting conditions. The behaviour of the animals was quantified by tracking the movements of the bell, using a high-speed camera. We found that the animals respond predictably to the darkening of one quadrant of the equatorial visual world by (1) increasing pulse frequency, (2) creating an asymmetry in the structure that constricts the outflow opening of the bell, the velarium, and (3) delaying contraction at one of the four sides of the bell. This causes the animals to orient their bell in such a way that, if not tethered, they would turn and swim away from the dark area. We conclude that the visual system of T. cystophora has a predictable effect on swimming behaviour.

  14. Shear deformable finite beam elements for composite box beams

    Science.gov (United States)

    Kim, Nam-Il; Choi, Dong-Ho

    2014-04-01

    The shear deformable thin-walled composite beams with closed cross-sections have been developed for coupled flexural, torsional, and buckling analyses. A theoretical model applicable to the thin-walled laminated composite box beams is presented by taking into account all the structural couplings coming from the material anisotropy and the shear deformation effects. The current composite beam includes the transverse shear and the restrained warping induced shear deformation by using the first-order shear deformation beam theory. Seven governing equations are derived for the coupled axial-flexural-torsional-shearing buckling based on the principle of minimum total potential energy. Based on the present analytical model, three different types of finite composite beam elements, namely, linear, quadratic and cubic elements are developed to analyze the flexural, torsional, and buckling problems. In order to demonstrate the accuracy and superiority of the beam theory and the finite beam elements developed by this study, numerical solutions are presented and compared with the results obtained by other researchers and the detailed three-dimensional analysis results using the shell elements of ABAQUS. Especially, the influences of the modulus ratio and the simplified assumptions in stress-strain relations on the deflection, twisting angle, and critical buckling loads of composite box beams are investigated. [Figure not available: see fulltext.

  15. Numerical Characterization of a Composite Bonded Wing-Box

    Science.gov (United States)

    Smeltzer, Stanley S., III; Lovejoy, Andrew E.; Satyanarayana, Arunkumar

    2008-01-01

    The development of composite wing structures has focused on the use of mechanical fasteners to join heavily-loaded areas, while bonded joints have been used only for select locations. The focus of this paper is the examination of the adhesive layer in a generic bonded wing box that represents a "fastenerless" or unitized structure in order to characterize the general behavior and failure mechanisms. A global/local approach was applied to study the response of the adhesive layer using a global shell model and a local shell/solid model. The wing box was analyzed under load to represent a high-g up-bending condition such that the strains in the composite sandwich face sheets are comparable to an expected design allowable. The global/local analysis indicates that at these wing load levels the strains in the adhesive layer are well within the adhesive's elastic region, such that yielding would not be expected in the adhesive layer. The global/local methodology appears to be a promising approach to evaluate the structural integrity of the adhesively bonded structures.

  16. Boxing as a sport activity associated with isolated GH deficiency.

    Science.gov (United States)

    Kelestimur, F; Tanriverdi, F; Atmaca, H; Unluhizarci, K; Selcuklu, A; Casanueva, F F

    2004-12-01

    Traumatic brain injury (TBI) has long been known as a cause of hypopituitarism, and it is characterized by a high prevalence of neuroendocrine abnormalities. Boxing, one of the most common combative sports, may also result in TBI. As far as we know, pituitary functions including GH status have not been investigated in boxers. Therefore, in this preliminary study, we have assessed the pituitary functions in boxers. Eleven actively competing or retired male boxers with a mean age of 38.0 +/- 3.6 yr and 7 age-, sex- and BMI-matched healthy non-boxing controls were included in the study. Biochemical and basal hormonal parameters including IGF-I levels were measured. To assess GH secretory status in boxers and healthy controls, GHRH (1 microg/kg)+GHRP-6 (1 microg/kg) test was performed. After GHRH+GHRP-6 test, mean peak GH level in boxers and in controls were 10.9 +/- 1.7 and 41.4 +/- 6.7 microg/l, respectively (p amateur, are needed to clarify pituitary dysfunction in boxers.

  17. Pothole Detection System Using a Black-box Camera.

    Science.gov (United States)

    Jo, Youngtae; Ryu, Seungki

    2015-11-19

    Aging roads and poor road-maintenance systems result a large number of potholes, whose numbers increase over time. Potholes jeopardize road safety and transportation efficiency. Moreover, they are often a contributing factor to car accidents. To address the problems associated with potholes, the locations and size of potholes must be determined quickly. Sophisticated road-maintenance strategies can be developed using a pothole database, which requires a specific pothole-detection system that can collect pothole information at low cost and over a wide area. However, pothole repair has long relied on manual detection efforts. Recent automatic detection systems, such as those based on vibrations or laser scanning, are insufficient to detect potholes correctly and inexpensively owing to the unstable detection of vibration-based methods and high costs of laser scanning-based methods. Thus, in this paper, we introduce a new pothole-detection system using a commercial black-box camera. The proposed system detects potholes over a wide area and at low cost. We have developed a novel pothole-detection algorithm specifically designed to work with the embedded computing environments of black-box cameras. Experimental results are presented with our proposed system, showing that potholes can be detected accurately in real-time.

  18. Pothole Detection System Using a Black-box Camera

    Directory of Open Access Journals (Sweden)

    Youngtae Jo

    2015-11-01

    Full Text Available Aging roads and poor road-maintenance systems result a large number of potholes, whose numbers increase over time. Potholes jeopardize road safety and transportation efficiency. Moreover, they are often a contributing factor to car accidents. To address the problems associated with potholes, the locations and size of potholes must be determined quickly. Sophisticated road-maintenance strategies can be developed using a pothole database, which requires a specific pothole-detection system that can collect pothole information at low cost and over a wide area. However, pothole repair has long relied on manual detection efforts. Recent automatic detection systems, such as those based on vibrations or laser scanning, are insufficient to detect potholes correctly and inexpensively owing to the unstable detection of vibration-based methods and high costs of laser scanning-based methods. Thus, in this paper, we introduce a new pothole-detection system using a commercial black-box camera. The proposed system detects potholes over a wide area and at low cost. We have developed a novel pothole-detection algorithm specifically designed to work with the embedded computing environments of black-box cameras. Experimental results are presented with our proposed system, showing that potholes can be detected accurately in real-time.

  19. Broadband set-top box using MAP-CA processor

    Science.gov (United States)

    Bush, John E.; Lee, Woobin; Basoglu, Chris

    2001-12-01

    Advances in broadband access are expected to exert a profound impact in our everyday life. It will be the key to the digital convergence of communication, computer and consumer equipment. A common thread that facilitates this convergence comprises digital media and Internet. To address this market, Equator Technologies, Inc., is developing the Dolphin broadband set-top box reference platform using its MAP-CA Broadband Signal ProcessorT chip. The Dolphin reference platform is a universal media platform for display and presentation of digital contents on end-user entertainment systems. The objective of the Dolphin reference platform is to provide a complete set-top box system based on the MAP-CA processor. It includes all the necessary hardware and software components for the emerging broadcast and the broadband digital media market based on IP protocols. Such reference design requires a broadband Internet access and high-performance digital signal processing. By using the MAP-CA processor, the Dolphin reference platform is completely programmable, allowing various codecs to be implemented in software, such as MPEG-2, MPEG-4, H.263 and proprietary codecs. The software implementation also enables field upgrades to keep pace with evolving technology and industry demands.

  20. The technological obsolescence of the Brazilian eletronic ballot box.

    Science.gov (United States)

    Camargo, Carlos Rogério; Faust, Richard; Merino, Eugênio; Stefani, Clarissa

    2012-01-01

    The electronic ballot box has played a significant role in the consolidation of Brazilian political process. It has enabled paper ballots extinction as a support for the elector's vote as well as for voting counting processes. It is also widely known that election automation has decisively collaborated to the legitimization of Brazilian democracy, getting rid of doubts about the winning candidates. In 1995, when the project was conceived, it represented a compromise solution, balancing technical efficiency and costs trade-offs. However, this architecture currently limits the ergonomic enhancements to the device operation, transportation, maintenance and storage. Nowadays are available in the market devices of reduced dimensions, based on novel computational architecture, namely tablet computers, which emphasizes usability, autonomy, portability, security and low power consumption. Therefore, the proposal under discussion is the replacement of the current electronic ballot boxes for tablet-based devices to improve the ergonomics aspects of the Brazilian voting process. These devices offer a plethora of integrated features (e.g., capacitive touchscreen, speakers, microphone) that enable highly usable and simple user interfaces, in addition to enhancing the voting process security mechanisms. Finally, their operational systems features allow for the development of highly secure applications, suitable to the requirements of a voting process.

  1. Protection mechanisms of the carapace of a box turtle.

    Science.gov (United States)

    An, Bingbing; Wagner, H Daniel

    2017-07-01

    In this study we explore the materials design principles of the carapace of a Terrapene Carolina box turtle, which possesses a sandwich-like structure consisting of a foam-like interior layer (FIL) enclosed by two dense exterior layers (DEL). A constitutive scheme accounting for the large deformation, plastic yielding and post-yield strain hardening caused by densification of the cells in the foam is developed to model the mechanical properties of the FIL, and a large deformation elastic-plastic model for the DEL is proposed. Computational simulations of the carapace subjected to indentation loading are performed and it is found that the layer sequence plays an essential role in the mechanical properties of the carapace. For the sandwich-like layering, the stiff DEL provides penetration resistance and the FIL contributes to the energy dissipation of the entire structure through plastic deformation, which enables reduction in back-deformations, enhanced penetration resistance and low stresses transmitted to the inner layer. For other layer sequential patterns, the contributions of the DEL and FIL are limited, leading to poorer mechanical performance. Based on these results, we propose that the sandwich-like structure of the carapace of the box turtle is designed to maintain sufficient resistance to penetration deformation, a defeating mechanism, and at the same time to significantly amplify energy dissipation, a defending mechanism. This double function could be used in the development of future human body armor. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Venom proteome of the box jellyfish Chironex fleckeri.

    Science.gov (United States)

    Brinkman, Diane L; Aziz, Ammar; Loukas, Alex; Potriquet, Jeremy; Seymour, Jamie; Mulvenna, Jason

    2012-01-01

    The nematocyst is a complex intracellular structure unique to Cnidaria. When triggered to discharge, the nematocyst explosively releases a long spiny, tubule that delivers an often highly venomous mixture of components. The box jellyfish, Chironex fleckeri, produces exceptionally potent and rapid-acting venom and its stings to humans cause severe localized and systemic effects that are potentially life-threatening. In an effort to identify toxins that could be responsible for the serious health effects caused by C. fleckeri and related species, we used a proteomic approach to profile the protein components of C. fleckeri venom. Collectively, 61 proteins were identified, including toxins and proteins important for nematocyte development and nematocyst formation (nematogenesis). The most abundant toxins identified were isoforms of a taxonomically restricted family of potent cnidarian proteins. These toxins are associated with cytolytic, nociceptive, inflammatory, dermonecrotic and lethal properties and expansion of this important protein family goes some way to explaining the destructive and potentially fatal effects of C. fleckeri venom. Venom proteins and their post-translational modifications (PTMs) were further characterized using toxin-specific antibodies and phosphoprotein/glycoprotein-specific stains. Results indicated that glycosylation is a common PTM of the toxin family while a lack of cross-reactivity by toxin-specific antibodies infers there is significant divergence in structure and possibly function among family members. This study provides insight into the depth and diversity of protein toxins produced by harmful box jellyfish and represents the first description of a cubozoan jellyfish venom proteome.

  3. Venom proteome of the box jellyfish Chironex fleckeri.

    Directory of Open Access Journals (Sweden)

    Diane L Brinkman

    Full Text Available The nematocyst is a complex intracellular structure unique to Cnidaria. When triggered to discharge, the nematocyst explosively releases a long spiny, tubule that delivers an often highly venomous mixture of components. The box jellyfish, Chironex fleckeri, produces exceptionally potent and rapid-acting venom and its stings to humans cause severe localized and systemic effects that are potentially life-threatening. In an effort to identify toxins that could be responsible for the serious health effects caused by C. fleckeri and related species, we used a proteomic approach to profile the protein components of C. fleckeri venom. Collectively, 61 proteins were identified, including toxins and proteins important for nematocyte development and nematocyst formation (nematogenesis. The most abundant toxins identified were isoforms of a taxonomically restricted family of potent cnidarian proteins. These toxins are associated with cytolytic, nociceptive, inflammatory, dermonecrotic and lethal properties and expansion of this important protein family goes some way to explaining the destructive and potentially fatal effects of C. fleckeri venom. Venom proteins and their post-translational modifications (PTMs were further characterized using toxin-specific antibodies and phosphoprotein/glycoprotein-specific stains. Results indicated that glycosylation is a common PTM of the toxin family while a lack of cross-reactivity by toxin-specific antibodies infers there is significant divergence in structure and possibly function among family members. This study provides insight into the depth and diversity of protein toxins produced by harmful box jellyfish and represents the first description of a cubozoan jellyfish venom proteome.

  4. [Dead-box RNA helicases in animal gametogenesis].

    Science.gov (United States)

    Kotov, A A; Akulenko, N V; Kibanov, M V; Olenina, L V

    2014-01-01

    This review analyzes and summarizes a current knowledge about a role of RNA helicases in the development and maintenance of gametogenesis of eukaryotic organisms. Here we focused on three representatives of RNA helicase family containing the characteristic motifs in the amino acid sequence (DEAD-box) and carrying substantial and conservative functions in the germinal tissues of various species from drosophila to human. There are such proteins as Vasa/DDX4, BelIe/DDX3 and Spindle-E/TDRD9. They are involved in a wide range of activities that are associated with the regulation of transcription, splicing, nuclear export, and especially with the initiation of translation. The expression of genes required for the gametogenesis appears to be regulated mainly at the translational level. RNA helicases are involved in the formation of cytoplasmic RNP granules and in the implementation of gene RNA-silencing. "DEAD-box RNA helicases" that carry highly homologous central domain, which determines their basic biochemical activity in the ATP-dependent unwinding of short RNA duplexes, perform the essential and non-overlapping functions in the germinal tissues.

  5. Innovation by design lessons from post box design & development

    CERN Document Server

    Chakravarthy, Battula Kalyana

    2013-01-01

    The book provides an in-depth knowledge on how a product is designed and developed by Product Designers. This has been achieved through a case study of one product – the Post Box. This product was chosen for the study primarily due to its simple and non-technical nature as that would make it easy for the readers to comprehend the design process. At the same time the Post Box posed all the challenges a designer would face while creating a new product. Through a step by step process the book gradually takes the reader through the design and development journey – right from understanding the product, identifying the user need through market research, comprehending client’s brief, generating product ideas and concepts to development of prototype, manufacturing and final performance of the product. The book illustrates the stages in the design process that lead to innovation which is applicable to all types of products. To make the book more stimulating, interesting facts, figures and pictures on related iss...

  6. Damping of Collective Oscillations in a Box Trap

    Science.gov (United States)

    Proukakis, Nick; Lee, Kean Loon; Zaremba, Eugene; Turzak, Patrik; Eigen, Chris; Gaunt, Alex; Smith, Rob; Hadzibabic, Zoran; Navon, Nir

    2017-04-01

    We model numerically the lowest-lying collective mode of a Bose gas in a box trap excited by a kick in the potential, as in a recent experiment. Our analysis is performed at finite temperatures (below the critical region), based on the so-called ``ZNG'' model, in which the condensate is described by a dissipative Gross-Pitaevskii equation which is itself self-consistently coupled to a dynamical thermal cloud described by a quantum Boltzmann equation `` a model which has proven most successful in describing damping observed in harmonic traps. For typical parameters probed far from the hydrodynamic region, we find a single oscillation - whose frequency agrees well with experiments - with the thermal cloud rapidly damping out higher frequency modes primarily through self-consistent dynamical mean-field coupling. Our results are confirmed by an independent analysis with the stochastic projected Gross-Pitaevskii equation. Intuitively, we find damping in a box trap to depend much more weakly on temperature than in harmonic traps, in broad agreement with experimental data. EPSRC; NSERC; ERC; Royal Society.

  7. Specific Genomic Fingerprints of Phosphate Solubilizing Pseudomonas Strains Generated by Box Elements

    Science.gov (United States)

    Javadi Nobandegani, Mohammad Bagher; Saud, Halimi Mohd; Yun, Wong Mui

    2014-01-01

    Primers corresponding to conserved bacterial repetitive of BOX elements were used to show that BOX-DNA sequences are widely distributed in phosphate solubilizing Pseudomonas strains. Phosphate solubilizing Pseudomonas was isolated from oil palm fields (tropical soil) in Malaysia. BOX elements were used to generate genomic fingerprints of a variety of Pseudomonas isolates to identify strains that were not distinguishable by other classification methods. BOX-PCR, that derived genomic fingerprints, was generated from whole purified genomic DNA by liquid culture of phosphate solubilizing Pseudomonas. BOX-PCR generated the phosphate solubilizing Pseudomonas specific fingerprints to identify the relationship between these strains. This suggests that distribution of BOX elements' sequences in phosphate solubilizing Pseudomonas strains is the mirror image of their genomic structure. Therefore, this method appears to be a rapid, simple, and reproducible method to identify and classify phosphate solubilizing Pseudomonas strains and it may be useful tool for fast identification of potential biofertilizer strains. PMID:25580434

  8. Nuclear factor ETF specifically stimulates transcription from promoters without a TATA box.

    Science.gov (United States)

    Kageyama, R; Merlino, G T; Pastan, I

    1989-09-15

    Transcription factor ETF stimulates the expression of the epidermal growth factor receptor (EGFR) gene which does not have a TATA box in the promoter region. Here, we show that ETF recognizes various GC-rich sequences including stretches of deoxycytidine or deoxyguanosine residues and GC boxes with similar affinities. ETF also binds to TATA boxes but with a lower affinity. ETF stimulated in vitro transcription from several promoters without TATA boxes but had little or no effect on TATA box-containing promoters even though they had strong ETF-binding sites. These inactive ETF-binding sites became functional when placed upstream of the EGFR promoter whose own ETF-binding sites were removed. Furthermore, when a TATA box was introduced into the EGFR promoter, the responsiveness to ETF was abolished. These results indicate that ETF is a specific transcription factor for promoters which do not contain TATA elements.

  9. BOX SPLINE BASED 3D TOMOGRAPHIC RECONSTRUCTION OF DIFFUSION PROPAGATORS FROM MRI DATA.

    Science.gov (United States)

    Ye, Wenxing; Portnoy, Sharon; Entezari, Alireza; Vemuri, Baba C; Blackband, Stephen J

    2011-06-09

    This paper introduces a tomographic approach for reconstruction of diffusion propagators, P( r ), in a box spline framework. Box splines are chosen as basis functions for high-order approximation of P( r ) from the diffusion signal. Box splines are a generalization of B-splines to multivariate setting that are particularly useful in the context of tomographic reconstruction. The X-Ray or Radon transform of a (tensor-product B-spline or a non-separable) box spline is a box spline - the space of box splines is closed under the Radon transform.We present synthetic and real multi-shell diffusion-weighted MR data experiments that demonstrate the increased accuracy of P( r ) reconstruction as the order of basis functions is increased.

  10. Prestressing force monitoring method for a box girder through distributed long-gauge FBG sensors

    Science.gov (United States)

    Chen, Shi-Zhi; Wu, Gang; Xing, Tuo; Feng, De-Cheng

    2018-01-01

    Monitoring prestressing forces is essential for prestressed concrete box girder bridges. However, the current monitoring methods used for prestressing force were not applicable for a box girder neither because of the sensor’s setup being constrained or shear lag effect not being properly considered. Through combining with the previous analysis model of shear lag effect in the box girder, this paper proposed an indirect monitoring method for on-site determination of prestressing force in a concrete box girder utilizing the distributed long-gauge fiber Bragg grating sensor. The performance of this method was initially verified using numerical simulation for three different distribution forms of prestressing tendons. Then, an experiment involving two concrete box girders was conducted to study the feasibility of this method under different prestressing levels preliminarily. The results of both numerical simulation and lab experiment validated this method’s practicability in a box girder.

  11. Distribusi Difference dari S-Box Berbasis Fungsi Balikan Pada GF(28

    Directory of Open Access Journals (Sweden)

    Andriani Adi Lestari

    2016-12-01

    Full Text Available Substitution-box (s-box is a basic component of block cipher which performs a substitution. Two powerful cryptanalysis techniques applied to block ciphers are linear cryptanalysis and differential cryptanalysis. The resistance against differential cryptanalysis can be achieved by eliminating high-probability differential trails. We should choose an s-box where the maximum difference propagation probability is as small as possible to eliminating high-probability differential trails. Nyberg proposed a method to construct the s-box by using the inverse mapping on a finite field then implements affine transformations on . In this study, we generate 47.104 s-box according to Nyberg. The experimental results showed that s-boxes have the maximum difference propagation probability with the same frequency.

  12. Phylogenetic Distribution and Evolutionary History of Bacterial DEAD-Box Proteins

    OpenAIRE

    López-Ramírez, Varinia; Alcaraz, Luis D; Moreno-Hagelsieb, Gabriel; Olmedo-Álvarez, Gabriela

    2011-01-01

    DEAD-box proteins are found in all domains of life and participate in almost all cellular processes that involve RNA. The presence of DEAD and Helicase_C conserved domains distinguish these proteins. DEAD-box proteins exhibit RNA-dependent ATPase activity in vitro, and several also show RNA helicase activity. In this study, we analyzed the distribution and architecture of DEAD-box proteins among bacterial genomes to gain insight into the evolutionary pathways that have shaped their history. W...

  13. Genome-wide identification and analysis of the SBP-box family genes under Phytophthora capsici stress in pepper (Capsicum annuum L.

    Directory of Open Access Journals (Sweden)

    Huai-Xia eZhang

    2016-04-01

    Full Text Available SQUAMOSA promoter binding protein (SBP-box genes encode plant-specific transcription factors that are extensively involved in many physiological and biochemical processes, including growth, development, and signal transduction. However, pepper (Capsicum annuum L. SBP-box family genes have not been well characterized. We investigated SBP-box family genes in the pepper genome and characterized these genes across both compatible and incompatible strain of Phytophthora capsici, and also under different hormone treatments. The results indicated that total 15 members were identified and distributed on 7 chromosomes of pepper. Phylogenetic analysis showed that SBP-box genes of pepper can be classified into six groups. In addition, duplication analysis within pepper genome, as well as between pepper and Arabidopsis genomes demonstrated that there are 4 pairs of homology of SBP-box genes in the pepper genome and 10 pairs between pepper and Arabidopsis genomes. Tissue-specific expression analysis of the CaSBP genes demonstrated their diverse spatiotemporal expression patterns. The expression profiles were similarly analyzed following exposure to P. capsici inoculation and hormone treatments. It was shown that 9 of the CaSBP genes (CaSBP01, 02, 03, 04, 05, 06, 11, 12 and 13 exhibited a dramatic up-regulation after compatible HX-9 strain (P. capsici inoculation, while CaSBP09 and CaSBP15 were down-regulated. In case of PC strain (P. capsici infection six of the CaSBP genes (CaSBP02, 05, 06, 11, 12 and 13 were arose while CaSBP14 was down regulated. Furthermore, Salicylic acid (SA, Methyl jasmonate (MeJA and their biosynthesis inhibitors treatment indicated that some of the CaSBP genes are potentially involved in these hormone regulation pathways. This genome-wide identification, as well as characterization of evolutionary relationships and expression profiles of the pepper CaSBP genes, will help to improve pepper stress tolerance in the future.

  14. A Novel Image Encryption Based on Algebraic S-box and Arnold Transform

    Science.gov (United States)

    Farwa, Shabieh; Muhammad, Nazeer; Shah, Tariq; Ahmad, Sohail

    2017-09-01

    Recent study shows that substitution box (S-box) only cannot be reliably used in image encryption techniques. We, in this paper, propose a novel and secure image encryption scheme that utilizes the combined effect of an algebraic substitution box along with the scrambling effect of the Arnold transform. The underlying algorithm involves the application of S-box, which is the most imperative source to create confusion and diffusion in the data. The speciality of the proposed algorithm lies, firstly, in the high sensitivity of our S-box to the choice of the initial conditions which makes this S-box stronger than the chaos-based S-boxes as it saves computational labour by deploying a comparatively simple and direct approach based on the algebraic structure of the multiplicative cyclic group of the Galois field. Secondly the proposed method becomes more secure by considering a combination of S-box with certain number of iterations of the Arnold transform. The strength of the S-box is examined in terms of various performance indices such as nonlinearity, strict avalanche criterion, bit independence criterion, linear and differential approximation probabilities etc. We prove through the most significant techniques used for the statistical analyses of the encrypted image that our image encryption algorithm satisfies all the necessary criteria to be usefully and reliably implemented in image encryption applications.

  15. Numerical analysis of biological clogging in two-dimensional sand box experiments

    DEFF Research Database (Denmark)

    Kildsgaard, J.; Engesgaard, Peter Knudegaard

    2001-01-01

    Two-dimensional models for biological clogging and sorptive tracer transport were used to study the progress of clogging in a sand box experiment. The sand box had been inoculated with a strip of bacteria and exposed to a continuous injection of nitrate and acetate. Brilliant Blue was regularly...... with the assumed linear constant Kd behaviour. It is demonstrated that the dimensionality of sand box experiments in comparison to column experiments results in a much lower reduction in hydraulic conductivity Žfactor of 100. and that the bulk hydraulic conductivity of the sand box decreased only slightly. However...

  16. Two high-mobility group box domains act together to underwind and kink DNA

    Energy Technology Data Exchange (ETDEWEB)

    Sánchez-Giraldo, R.; Acosta-Reyes, F. J. [Universitat Politecnica de Catalunya, 08028 Barcelona (Spain); Malarkey, C. S. [University of Colorado School of Medicine, Aurora, CO 80045 (United States); Saperas, N. [Universitat Politecnica de Catalunya, 08028 Barcelona (Spain); Churchill, M. E. A., E-mail: mair.churchill@ucdenver.edu [University of Colorado School of Medicine, Aurora, CO 80045 (United States); Campos, J. L., E-mail: mair.churchill@ucdenver.edu [Universitat Politecnica de Catalunya, 08028 Barcelona (Spain)

    2015-06-30

    The crystal structure of HMGB1 box A bound to an unmodified AT-rich DNA fragment is reported at a resolution of 2 Å. A new mode of DNA recognition for HMG box proteins is found in which two box A domains bind in an unusual configuration generating a highly kinked DNA structure. High-mobility group protein 1 (HMGB1) is an essential and ubiquitous DNA architectural factor that influences a myriad of cellular processes. HMGB1 contains two DNA-binding domains, box A and box B, which have little sequence specificity but have remarkable abilities to underwind and bend DNA. Although HMGB1 box A is thought to be responsible for the majority of HMGB1–DNA interactions with pre-bent or kinked DNA, little is known about how it recognizes unmodified DNA. Here, the crystal structure of HMGB1 box A bound to an AT-rich DNA fragment is reported at a resolution of 2 Å. Two box A domains of HMGB1 collaborate in an unusual configuration in which the Phe37 residues of both domains stack together and intercalate the same CG base pair, generating highly kinked DNA. This represents a novel mode of DNA recognition for HMGB proteins and reveals a mechanism by which structure-specific HMG boxes kink linear DNA.

  17. Hubungan Metilasi DNA dengan Ekspresi Gen MADS-box pada Buah Mantel Tanaman Kelapa Sawit (Elaeis guineensis Jacq.

    Directory of Open Access Journals (Sweden)

    Maharani Anischan

    2015-03-01

    Full Text Available ABSTRACT The presence of mantled fruit on large-scale clonal production of oil palm had trully decreased the oil productivity. Mantled phenotype is likely to be that of an epigenetic change involving DNA methylation and the MADS-box transcription factor gene which encoded floral organ homeotic transformation. The objectives of this research were to quantify the degree of methylation which determined fruit abnormality through Ultra Performance Liquid Chromatography (UPLC and to study its correlation with the MADS-box EgAGL6, EgAG2, and EgAGA genes expressed on mantled fruit derived from oil palm clonal plants which have been quantified using Quantitative Real-Time PCR (qPCR. This research was arranged in two replications for each gene and cDNA. The expression of the target genes were compared to EF1-α1 as the reference gene. Through the Least Significant Difference (LSD Test at 95% confidence level of qPCR result, EgAGL6 expression was significantly lower in mantled fruit which decreased from 1.88 fold in Abn m to 0.46 fold in Abn. EgAG2 expression was increased non-significantly from 0.91 fold in Abn m to 1.13 fold in Abn, while EgAGA expression was higher in mantled which increased significantly from 1.48 fold in Abn m to 1.71 fold  in Abn. Nuclease S1 digestion and UPLC revealed the genome-wide increase in DNA methylation on mantled fruit (18.33-19.55% compared to its normal counterparts (5.67%. This increased in global DNA methylation was showed by the significant decreased in EgAGL6 transcript level of mantled fruit. This gene assumed to be involved in the development of mantled fruit. Keywords: DNA-methylation, MADS-box genes, Mantled fruit, Quantitative Real-Time PCR

  18. Considering Plants.

    Science.gov (United States)

    Flannery, Maura C.

    1991-01-01

    Examples from research that incorporate plants to illustrate biological principles are presented. Topics include dried pea shape, homeotic genes, gene transcription in plants that are touched or wounded, production of grasslands, seaweed defenses, migrating plants, camouflage, and family rivalry. (KR)

  19. Preservative effect of various indigenous plants on fermented milk ...

    African Journals Online (AJOL)

    SARAH

    2014-01-31

    Jan 31, 2014 ... 2Department of Food Science and Technology of Jomo Kenyatta University of Agriculture and Technology, P. O. Box. 62000-00200 ... ABSTRACT. Objective: This study was conducted to verify the claim that incorporation of indigenous plants in milk .... standardized0.1M Sodium hydroxide until the first color.

  20. Performance comparison of plant root biofilm, gravel attached ...

    African Journals Online (AJOL)

    Performance comparison of plant root biofilm, gravel attached biofilm and planktonic microbial populations, in phenol removal within a constructed wetland wastewater treatment system. Eyal Kurzbaum1*, Felix Kirzhner2 and Robert Armon2. 1Golan Research Institute, University of Haifa, P.O. Box 97, Katzrin 12900, Israel.

  1. Box models for the evolution of atmospheric oxygen: an update

    Science.gov (United States)

    Kasting, J. F.

    1991-01-01

    A simple 3-box model of the atmosphere/ocean system is used to describe the various stages in the evolution of atmospheric oxygen. In Stage I, which probably lasted until redbeds began to form about 2.0 Ga ago, the Earth's surface environment was generally devoid of free O2, except possibly in localized regions of high productivity in the surface ocean. In Stage II, which may have lasted for less than 150 Ma, the atmosphere and surface ocean were oxidizing, while the deep ocean remained anoxic. In Stage III, which commenced with the disappearance of banded iron formations around 1.85 Ga ago and has lasted until the present, all three surface reservoirs contained appreciable amounts of free O2. Recent and not-so-recent controversies regarding the abundance of oxygen in the Archean atmosphere are identified and discussed. The rate of O2 increase during the Middle and Late Proterozoic is identified as another outstanding question.

  2. Packing Boxes into Multiple Containers Using Genetic Algorithm

    Science.gov (United States)

    Menghani, Deepak; Guha, Anirban

    2016-07-01

    Container loading problems have been studied extensively in the literature and various analytical, heuristic and metaheuristic methods have been proposed. This paper presents two different variants of a genetic algorithm framework for the three-dimensional container loading problem for optimally loading boxes into multiple containers with constraints. The algorithms are designed so that it is easy to incorporate various constraints found in real life problems. The algorithms are tested on data of standard test cases from literature and are found to compare well with the benchmark algorithms in terms of utilization of containers. This, along with the ability to easily incorporate a wide range of practical constraints, makes them attractive for implementation in real life scenarios.

  3. Divergent polo box domains underpin the unique kinetoplastid kinetochore.

    Science.gov (United States)

    Nerusheva, Olga O; Akiyoshi, Bungo

    2016-03-01

    Kinetochores are macromolecular machines that drive eukaryotic chromosome segregation by interacting with centromeric DNA and spindle microtubules. While most eukaryotes possess conventional kinetochore proteins, evolutionarily distant kinetoplastid species have unconventional kinetochore proteins, composed of at least 19 proteins (KKT1-19). Polo-like kinase (PLK) is not a structural kinetochore component in either system. Here, we report the identification of an additional kinetochore protein, KKT20, in Trypanosoma brucei. KKT20 has sequence similarity with KKT2 and KKT3 in the Cys-rich region, and all three proteins have weak but significant similarity to the polo box domain (PBD) of PLK. These divergent PBDs of KKT2 and KKT20 are sufficient for kinetochore localization in vivo. We propose that the ancestral PLK acquired a Cys-rich region and then underwent gene duplication events to give rise to three structural kinetochore proteins in kinetoplastids. © 2016 The Authors.

  4. Orion Entry Performance-Based Center-of-Gravity Box

    Science.gov (United States)

    Rea, Jeremy R.

    2010-01-01

    The Orion capsule has many performance requirements for its atmospheric entry trajectory. Requirements on landing accuracy, maximum heating rate, total heat load, propellant usage, and sensed acceleration must all be satised. It is desired to define a methodology to translate the many performance requirements for an atmospheric entry trajectory into language easily understood by vehicle designers in terms of an allowable center-of-gravity box. This is possible by noting that most entry performance parameters for a capsule vehicle are mainly determined by the lift-to-drag ratio of the vehicle. However, the lift-to- drag ratio should be considered a probabilistic quantity rather than deterministic, where variations in the lift-to-drag are caused by both aerodynamic and center-of-gravity un- certainties. This paper discusses the technique used by the Orion program to define the allowable dispersions in center-of-gravity to achieve the desired entry performance while accounting for aerodynamic uncertainty.

  5. Opening the "black box" of current creativity research

    DEFF Research Database (Denmark)

    Hoffmann Birk, Rasmus; Ernø, Steffen

    -2012. The sub-fields were chosen because of their prominence in psychological research and research on creativity. The articles were procured from the PsycINFO database, with selection criteria being that they must be peer-reviewed and empirical studies. Typical definitions of creativity were "novelty plus......This presentation aims to problematise the ways in which creativity is defined and measured in recent studies on the topic. For this purpose, we analyzed 58 articles on creativity, selected from within the sub-fields of neuropsychology, psychometrics and developmental psychology published from 2009...... of empirical findings in regards to creativity as a phenomenon. Creativity itself thus becomes a "black box", rarely opened to investigation. Creativity research could therefore benefit from a more sustained relfection over its theoretical and methodological underpinnings as well as shifting its focus towards...

  6. World title boxing: from early beginnings to the first bell.

    Science.gov (United States)

    Schinke, Robert J; Ramsay, Marc

    2009-11-01

    There is scant literature where applied sport scientists have considered first hand experiences preparing professional boxers for world title bouts. The present submission reflects more than 10 years of applied experience working with professional boxers, residing in Canada. What follows is a composite of sequential steps that ownership and coaching staff of one Canadian management group have tried leading up to more than 20 world title bout experiences. The strategies proposed have been built progressively over time, and what follows is a general overview of a more detailed pre-bout structure from shortly in advance of a world title bout offer to the moment when the athlete enters the ring to perform. We propose that an effective structure is founded upon detailed a priori preparation, tactical decisions throughout bout preparation, and a thorough understanding by the athlete of what he will encounter during the title bout. Key PointsWorld championship boxing.Competition preparation.Professional sport.Athlete performance.

  7. A Quantitative Vainberg Method for Black Box Scattering

    Science.gov (United States)

    Galkowski, Jeffrey

    2017-01-01

    We give a quantitative version of Vainberg's method relating pole free regions to propagation of singularities for black box scatterers. In particular, we show that there is a logarithmic resonance free region near the real axis of size {τ} with polynomial bounds on the resolvent if and only if the wave propagator gains derivatives at rate {τ}. Next we show that if there exist singularities in the wave trace at times tending to infinity which smooth at rate {τ}, then there are resonances in logarithmic strips whose width is given by {τ}. As our main application of these results, we give sharp bounds on the size of resonance free regions in scattering on geometrically nontrapping manifolds with conic points. Moreover, these bounds are generically optimal on exteriors of nontrapping polygonal domains.

  8. Automated Box-Cox Transformations for Improved Visual Encoding.

    Science.gov (United States)

    Maciejewski, Ross; Pattath, Avin; Ko, Sungahn; Hafen, Ryan; Cleveland, William S; Ebert, David S

    2013-01-01

    The concept of preconditioning data (utilizing a power transformation as an initial step) for analysis and visualization is well established within the statistical community and is employed as part of statistical modeling and analysis. Such transformations condition the data to various inherent assumptions of statistical inference procedures, as well as making the data more symmetric and easier to visualize and interpret. In this paper, we explore the use of the Box-Cox family of power transformations to semiautomatically adjust visual parameters. We focus on time-series scaling, axis transformations, and color binning for choropleth maps. We illustrate the usage of this transformation through various examples, and discuss the value and some issues in semiautomatically using these transformations for more effective data visualization.

  9. Quantum computing with black-box quantum subroutines

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Jayne [Centre for Quantum Technologies, National University of Singapore, 3 Science Drive 2, 117543 Singapore (Singapore); Gu, Mile [Center for Quantum Information, Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing (China); Centre for Quantum Technologies, National University of Singapore, 3 Science Drive 2, 117543 Singapore (Singapore); Modi, Kavan [School of Physics, Monash University, Clayton, Victoria 3800 (Australia); Vedral, Vlatko [Department of Physics, University of Oxford, Clarendon Laboratory, Oxford, OX1 3PU (United Kingdom); Centre for Quantum Technologies, National University of Singapore, 3 Science Drive 2, 117543 Singapore (Singapore); Department of Physics, National University of Singapore, 2 Science Drive 3, 117551 Singapore (Singapore)

    2014-07-01

    In classical computation a subroutine is treated as a black box and we do not need to know its exact physical implementation to use it. A complex problem can be decomposed into smaller problems using such modularity. We show that quantum mechanically applying an unknown quantum process as a subroutine is impossible, and this restricts computation models such as DQC1 from operating on unknown inputs. We present a method to avoid this situation for certain computational problems and apply to a modular version of Shor's factoring algorithm. We examine how quantum entanglement and discord fare in this implementation. In this way we are able to study the role of discord in Shor's factoring algorithm.

  10. Motivating crowding theory - opening the black box of intrinsic motivation

    DEFF Research Database (Denmark)

    Jacobsen, Christian Bøtcher

    2010-01-01

    employees. Motivation crowding theory claims that this may be at the expense of intrinsic motivation, if the extrinsic motivation factor is perceived to be controlling. On the other hand, intrinsic motivation will be enhanced (crowded in), if the extrinsic motivation factor is perceived to be supportive......Public employees work for many other reasons than because they are paid for it. In other words, intrinsic motivation is an important determinant for their performance. Nonetheless, public sector organizations increasingly rely on extrinsic motivation factors such as monetary incentives to motivate....... Studies have found support for the motivation crowding claim, but have neglected intrinsic motivation. This study opens the black box of intrinsic motivation and finds a meaningful distinction between task motivation and public service motivation. Among 2,772 physiotherapists in the Danish public sector...

  11. 40 CFR 158.660 - Nontarget plant protection data requirements table.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Ecological Effects § 158.660 Nontarget plant... required for contained pesticide treatments such as bait boxes and pheromone traps unless adverse effects... table to determine the nontarget plant data requirements for a particular pesticide product. Notes that...

  12. Development of robot arm for automatic analytical operation in nuclear reprocessing plant

    Energy Technology Data Exchange (ETDEWEB)

    Shibayama, S.; Ohnishi, K. [Mitsubishi Heavy Industries Ltd., Kobe (Japan); Hayashibara, H. [Mitsubishi Heavy Industries Ltd., Takasago Research and Development Center, Takasago-shi, Hyogo-Ken (Japan)

    1998-07-01

    The analytical work in the nuclear reprocessing plant is very important role to operate the plant in normal and safety. The new compact robot arm has been developed for the automatic analytical system installed in the analytical box with the heavy shielding and confirmed the availability for this system by results of several validation tests. (author)

  13. Box-Cox Mixed Logit Model for Travel Behavior Analysis

    Science.gov (United States)

    Orro, Alfonso; Novales, Margarita; Benitez, Francisco G.

    2010-09-01

    To represent the behavior of travelers when they are deciding how they are going to get to their destination, discrete choice models, based on the random utility theory, have become one of the most widely used tools. The field in which these models were developed was halfway between econometrics and transport engineering, although the latter now constitutes one of their principal areas of application. In the transport field, they have mainly been applied to mode choice, but also to the selection of destination, route, and other important decisions such as the vehicle ownership. In usual practice, the most frequently employed discrete choice models implement a fixed coefficient utility function that is linear in the parameters. The principal aim of this paper is to present the viability of specifying utility functions with random coefficients that are nonlinear in the parameters, in applications of discrete choice models to transport. Nonlinear specifications in the parameters were present in discrete choice theory at its outset, although they have seldom been used in practice until recently. The specification of random coefficients, however, began with the probit and the hedonic models in the 1970s, and, after a period of apparent little practical interest, has burgeoned into a field of intense activity in recent years with the new generation of mixed logit models. In this communication, we present a Box-Cox mixed logit model, original of the authors. It includes the estimation of the Box-Cox exponents in addition to the parameters of the random coefficients distribution. Probability of choose an alternative is an integral that will be calculated by simulation. The estimation of the model is carried out by maximizing the simulated log-likelihood of a sample of observed individual choices between alternatives. The differences between the predictions yielded by models that are inconsistent with real behavior have been studied with simulation experiments.

  14. Injury and injury rates in Muay Thai kick boxing.

    Science.gov (United States)

    Gartland, S; Malik, M H; Lovell, M E

    2001-10-01

    To determine the type and number of injuries that occur during the training and practice of Muay Thai kick boxing and to compare the data obtained with those from previous studies of karate and taekwondo. One to one interviews using a standard questionnaire on injuries incurred during training and practice of Muay Thai kick boxing were conducted at various gyms and competitions in the United Kingdom and a Muay Thai gala in Holland. A total of 152 people were questioned, 132 men and 20 women. There were 19 beginners, 82 amateurs, and 51 professionals. Injuries to the lower extremities were the most common in all groups. Head injuries were the second most common in professionals and amateurs. Trunk injuries were the next most common in beginners. The difference in injury distribution among the three groups was significant (p< or =0.01). Soft tissue trauma was the most common type of injury in the three groups. Fractures were the second most common in professionals, and in amateurs and beginners it was sprains and strains (p< or =0.05). Annual injury rates were: beginners, 13.5/1000 participants; amateurs, 2.43/1000 participants; professionals, 2.79/1000 participants. For beginners, 7% of injuries resulted in seven or more days off training; for amateurs and professionals, these values were 4% and 5.8% respectively. The results are similar to those found for karate and taekwondo with regard to injury distribution, type, and rate. The percentage of injuries resulting in time off training is less.

  15. An in silico analysis of T-box regulated genes and T-box evolution in prokaryotes, with emphasis on prediction of substrate specificity of transporters

    Directory of Open Access Journals (Sweden)

    Kleerebezem Michiel

    2008-07-01

    Full Text Available Abstract Background T-box anti-termination is an elegant and sensitive mechanism by which many bacteria maintain constant levels of amino acid-charged tRNAs. The amino acid specificity of the regulatory element is related to a so-called specifier codon and can in principle be used to guide the functional annotation of the genes controlled via the T-box anti-termination mechanism. Results Hidden Markov Models were defined to search the T-box regulatory element and were applied to all completed prokaryotic genomes. The vast majority of the genes found downstream of the retrieved elements encoded functionalities related to transport and synthesis of amino acids and the charging of tRNA. This is completely in line with findings reported in literature and with the proposed biological role of the regulatory element. For several species, the functional annotation of a large number of genes encoding proteins involved in amino acid transport could be improved significantly on basis of the amino acid specificity of the identified T-boxes. In addition, these annotations could be extrapolated to a larger number of orthologous systems in other species. Analysis of T-box distribution confirmed that the element is restricted predominantly to species of the phylum Firmicutes. Furthermore, it appeared that the distribution was highly species specific and that in the case of amino acid transport some boxes seemed to "pop-up" only recently. Conclusion We have demonstrated that the identification of the molecular specificity of a regulatory element can be of great help in solving notoriously difficult annotation issues, e.g. by defining the substrate specificity of genes encoding amino acid transporters on basis of the amino acid specificity of the regulatory T-box. Furthermore, our analysis of the species-dependency of the occurrence of specific T-boxes indicated that these regulatory elements propagate in a semi-independent way from the genes that they control.

  16. Phylogeny and divergence of basal angiosperms inferred from APETALA3- and PISTILLATA-like MADS-box genes.

    Science.gov (United States)

    Aoki, Seishiro; Uehara, Koichi; Imafuku, Masao; Hasebe, Mitsuyasu; Ito, Motomi

    2004-06-01

    The B-class MADS-box genes composed of APETALA3 ( AP3) and PISTILLATA ( PI) lineages play an important role in petal and stamen identity in previously studied flowering plants. We investigated the diversification of the AP3-like and PI-like MADS-box genes of eight species in five basal angiosperm families: Amborella trichopoda (Amborellaceae); Brasenia schreberi and Cabomba caroliniana (Cabombaceae); Euryale ferox, Nuphar japonicum, and Nymphaea tetragona (Nymphaeaceae); Illicium anisatum (Illiciaceae); and Kadsura japonica (Schisandraceae). Sequence analysis showed that a four amino acid deletion in the K domain, which was found in all previously reported angiosperm PI genes, exists in a PI homologue of Schisandraceae, but not in six PI homologues of the Amborellaceae, Cabombaceae, and Nymphaeaceae, suggesting that the Amborellaceae, Cabombaceae, and Nymphaeaceae are basalmost lineages in angiosperms. The results of molecular phylogenetic analyses were not inconsistent with this hypothesis. The AP3 and PI homologues from Amborella share a sequence of five amino acids in the 5' region of exon 7. Using the linearized tree and likelihood methods, the divergence time between the AP3 and PI lineages was estimated as somewhere between immediately after to several tens of millions of years after the split between angiosperms and extant gymnosperms. Estimates of the age of the most recent common ancestor of all extant angiosperms range from approximately 140-210 Ma, depending on the trees used and assumptions made.

  17. Application of a Box-Behnken design for optimizing the extraction process of agave fructans (Agave tequilana Weber var. Azul).

    Science.gov (United States)

    Flores-Girón, Emmanuel; Salazar-Montoya, Juan Alfredo; Ramos-Ramírez, Emma Gloria

    2016-08-01

    Agave (Agave tequilana Weber var. Azul) is an industrially important crop in México since it is the only raw material appropriate to produce tequila, an alcoholic beverage. Nowadays, however, these plants have also a nutritional interest as a source of functional food ingredients, owing to the prebiotic potential of agave fructans. In this study, a Box-Behnken design was employed to determine the influence of temperature, liquid:solid ratio and time in a maceration process for agave fructan extraction and optimization. The developed regression model indicates that the selected study variables were statistical determinants for the extraction yield, and the optimal conditions for maximum extraction were a temperature of 60 °C, a liquid:solid ratio of 10:1 (v/w) and a time of 26.7 min, corresponding to a predicted extraction yield of 37.84%. Through selective separation via precipitation with ethanol, fructans with a degree of polymerization of 29.1 were obtained. Box-Behnken designs are useful statistical methods for optimizing the extraction process of agave fructans. A mixture of carbohydrates was obtained from agave powder. This optimized method can be used to obtain fructans for use as prebiotics or as raw material for obtaining functional oligosaccharides. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  18. Carbon Molecular Sieve Membrane as a True One Box Unit for Large Scale Hydrogen Production

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Paul

    2012-05-01

    IGCC coal-fired power plants show promise for environmentally-benign power generation. In these plants coal is gasified to syngas then processed in a water gas-shift (WGS) reactor to maximize the hydrogen/CO{sub 2} content. The gas stream can then be separated into a hydrogen rich stream for power generation and/or further purified for sale as a chemical and a CO{sub 2} rich stream for the purpose of carbon capture and storage (CCS). Today, the separation is accomplished using conventional absorption/desorption processes with post CO{sub 2} compression. However, significant process complexity and energy penalties accrue with this approach, accounting for ~20% of the capital cost and ~27% parasitic energy consumption. Ideally, a one-box process is preferred in which the syngas is fed directly to the WGS reactor without gas pre-treatment, converting the CO to hydrogen in the presence of H{sub 2}S and other impurities and delivering a clean hydrogen product for power generation or other uses. The development of such a process is the primary goal of this project. Our proposed "one-box" process includes a catalytic membrane reactor (MR) that makes use of a hydrogen-selective, carbon molecular sieve (CMS) membrane, and a sulfur-tolerant Co/Mo/Al{sub 2}O{sub 3} catalyst. The membrane reactor's behavior has been investigated with a bench top unit for different experimental conditions and compared with the modeling results. The model is used to further investigate the design features of the proposed process. CO conversion >99% and hydrogen recovery >90% are feasible under the operating pressures available from IGCC. More importantly, the CMS membrane has demonstrated excellent selectivity for hydrogen over H{sub 2}S (>100), and shown no flux loss in the presence of a synthetic "tar"-like material, i.e., naphthalene. In summary, the proposed "one-box" process has been successfully demonstrated with the bench-top reactor. In parallel we have successfully designed and

  19. Does previous use affect litter box appeal in multi-cat households?

    Science.gov (United States)

    Ellis, J J; McGowan, R T S; Martin, F

    2017-08-01

    It is commonly assumed that cats actively avoid eliminated materials (especially in multi-cat homes), suggesting regular litter box cleaning as the best defense against out-of-box elimination. The relationship between previous use and litter box appeal to familiar subsequent users is currently unknown. The purpose of this study was to investigate the relationship between previous litter box use and the identity of the previous user, type of elimination, odor, and presence of physical/visual obstructions in a multi-cat household scenario. Cats preferred a clean litter box to a dirty one, but the identity of the previous user had no impact on preferences. While the presence of odor from urine and/or feces did not impact litter box preferences, the presence of odorless faux-urine and/or feces did - with the presence of faux-feces being preferred over faux-urine. Results suggest neither malodor nor chemical communication play a role in litter box preferences, and instead emphasize the importance of regular removal of physical/visual obstructions as the key factor in promoting proper litter box use. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  20. Estimation of Radiation Limit from a Huygens' Box under Non-Free-Space Conditions

    DEFF Research Database (Denmark)

    Franek, Ondrej; Sørensen, Morten; Bonev, Ivan Bonev

    2013-01-01

    The recently studied Huygens' box method has difficulties when radiation of an electronic module is to be determined under non-free-space conditions, i.e. with an enclosure. We propose an estimate on radiation limit under such conditions based only on the Huygens' box data from free...

  1. Sex Differences in a Human Analogue of the Radial Arm Maze: The ''17-Box Maze Test''

    Science.gov (United States)

    Rahman, Q.; Abrahams, S.; Jussab, F.

    2005-01-01

    This study investigated sex differences in spatial memory using a human analogue of the Radial Arm Maze: a revision on the Nine Box Maze originally developed by Abrahams, Pickering, Polkey, and Morris (1997) called the 17-Box Maze Test herein. The task encourages allocentric spatial processing, dissociates object from spatial memory, and…

  2. Making the Black Box of Collaborative Learning Transparent: Combining Process-Oriented and Cognitive Load Approaches

    Science.gov (United States)

    Janssen, Jeroen; Kirschner, Femke; Erkens, Gijsbert; Kirschner, Paul A.; Paas, Fred

    2010-01-01

    Traditional research on collaborative learning employs a "black box" approach that makes it difficult to gain a deeper understanding of the differential effects of collaborative learning. To make the black box transparent, researchers have studied the process of collaboration, in order to establish which interaction features are likely to make…

  3. Exploring the "Black Box" of Programming: Applying Systematic Implementation Evaluation to a Structured Camp Curriculum

    Science.gov (United States)

    Mainieri, Tracy L.; Anderson, Denise M.

    2015-01-01

    Camp scholars have designed structured curricula to engender specific outcomes and to break down the "black box" of programming. Implementation evaluation explores how well a program operates when delivered, further breaking down the black box. The purpose of this study was to explore the implementation of a new structured camp…

  4. The Roles of T-Box Genes in Vertebrate Limb Development.

    Science.gov (United States)

    Sheeba, C J; Logan, M P O

    2017-01-01

    Members of the T-box gene family have diverse roles during embryogenesis and many play critical roles in the developing limb. This is exemplified by the fact that, in humans, mutations in T-box genes are associated with several congenital syndromes that include limb defects as part of their characteristic spectrum of abnormalities. T-box genes encode for evolutionary conserved transcription factors that include both transcriptional activators and repressors. The hallmark of T-box gene members is the presence of the eponymous DNA-binding T-box domain. There are 17 mammalian T-box genes, which based on the sequence homology of the T-box domain, are grouped into five subfamilies, namely, T, Tbx1, Tbx2, Tbx6, and Tbr1. At least nine T-box genes are expressed during limb development with distinct and dynamic expression patterns. All four members of Tbx2 subfamily (Tbx2, Tbx3, Tbx4, Tbx5) and three members of Tbx1 (Tbx1, Tbx15, Tbx18), Brachyury (T) and Eomes (Tbr2) are expressed in the developing limb. © 2017 Elsevier Inc. All rights reserved.

  5. Optical and near-infrared observations of the GRB 970616 error box

    DEFF Research Database (Denmark)

    Gorosabel, J.; Castro-Tirado, A.J.; Pedersen, Henrik

    1999-01-01

    We report on near-infrared and optical observations of the GRB 970616 error box and of the X-ray sources discovered by ASCA and ROSAT in the region. No optical transient was found either within the IPN band or in the X-ray error boxes, similarly to other bursts, and we suggest that either...

  6. review of elastic analys ew of elastic analysis of box girder bridges ...

    African Journals Online (AJOL)

    eobe

    Tel: +234-803-746-2228. REVIEW OF ELASTIC ANALYS. DEPARTMENT OF CIVIL ENGINEERING. E-mail ...... concrete box girder bridge, the Lavic Road bridge in. California, monitored over a 2-year period from ..... analysis of curved steel box beams, Masters Thesis,. University of Maryland. 52. Oleinik, J. C., and Heins, ...

  7. Comparative analysis of profitability of honey production using traditional and box hives.

    Science.gov (United States)

    Al-Ghamdi, Ahmed A; Adgaba, Nuru; Herab, Ahmed H; Ansari, Mohammad J

    2017-07-01

    Information on the profitability and productivity of box hives is important to encourage beekeepers to adopt the technology. However, comparative analysis of profitability and productivity of box and traditional hives is not adequately available. The study was carried out on 182 beekeepers using cross sectional survey and employing a random sampling technique. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), the Cobb-Douglas (CD) production function and partial budgeting. The CD production function revealed that supplementary bee feeds, labor and medication were statistically significant for both box and traditional hives. Generally, labor for bee management, supplementary feeding, and medication led to productivity differences of approximately 42.83%, 7.52%, and 5.34%, respectively, between box and traditional hives. The study indicated that productivity of box hives were 72% higher than traditional hives. The average net incomes of beekeepers using box and traditional hives were 33,699.7 SR/annum and 16,461.4 SR/annum respectively. The incremental net benefit of box hives over traditional hives was nearly double. Our study results clearly showed the importance of adoption of box hives for better productivity of the beekeeping subsector.

  8. Norm Scores of the Box and Block Test for Children Ages 3-10 Years

    NARCIS (Netherlands)

    Jongbloed-Pereboom, M.; Nijhuis-Van der Sanden, M.W.G.; Steenbergen, B.

    2013-01-01

    This study provides new norm scores for the Box and Block Test for gross manual dexterity in children ages 3-10 yr. Two hundred fifteen Dutch children performed the Box and Block Test separately with each hand. We found an age effect for the scores; older children obtained higher scores than younger

  9. Norm scores of the box and block test for children ages 3-10 years

    NARCIS (Netherlands)

    Jongbloed-Pereboom, M.; Nijhuis-Van der Sanden, M.W.G.; Steenbergen, B.

    2013-01-01

    This study provides new norm scores for the Box and Block Test for gross manual dexterity in children ages 3-10 yr. Two hundred fifteen Dutch children performed the Box and Block Test separately with each hand. We found an age effect for the scores; older children obtained higher scores than younger

  10. Opening the Big Black Box: European study reveals visitors' impressions of science laboratories

    CERN Multimedia

    2004-01-01

    "On 29 - 30 March the findings of 'Inside the Big Black Box'- a Europe-wide science and society project - will be revealed during a two-day seminar hosted by CERN*. The principle aim of Inside the Big Black Box (IN3B) is to determine whether a working scientific laboratory can capture the curiosity of the general public through visits" (1 page)

  11. Conditional Re‐encoding Method for Cryptanalysis‐Resistant White‐Box AES

    National Research Council Canada - National Science Library

    Lee, Seungkwang; Choi, Dooho; Choi, Yong‐Je

    2015-01-01

    .... For this reason, cryptographic algorithms have been redesigned to be resistant to white‐box attacks. The first white‐box AES (WB‐AES) implementation was thought to provide reliable security in that all brute force attacks are infeasible even in white...

  12. Industrial X-ray tomography using an electron beam welding box

    CERN Document Server

    Hoppe, D; Koch, D; Zippe, C

    2002-01-01

    An existing electron beam welding box should be used with the least additional effort for X-ray tomography. Only a suitable anode, a simple device to turn the investigated object and one detector for X-rays are placed into the vacuum of the welding box. The information necessary to reconstruct tomograms should be derived only from the measurand of the detector.

  13. The Power of Refutational Text: Changing Intuitions about the Interpretation of Box Plots

    Science.gov (United States)

    Lem, Stephanie; Onghena, Patrick; Verschaffel, Lieven; Van Dooren, Wim

    2017-01-01

    Graphicacy is an important skill in today's society; however, the interpretation of graphs proofs to be more difficult than it might seem. In this study, we focus on one specific misinterpretation, the area misinterpretation of box plots, which is caused by incorrect heuristic processing of salient features of the box plot. In this study, we tried…

  14. Smocks and Jocks outside the Box: The Paradigmatic Evolution of Sport and Exercise Psychology

    Science.gov (United States)

    Vealey, Robin S.

    2006-01-01

    The objective of this article is to describe the historical development of sport and exercise psychology, with a particular emphasis on the construction and evolution of the "box" through history. The box represents the dominant paradigm that serves as the model for research and application as it evolves through successive historical eras (Kuhn,…

  15. Analytic solutions for groundwater whirls in box-shaped, layered anisotropic aquifers.

    NARCIS (Netherlands)

    Bakker, M.; Hemker, C.J.

    2004-01-01

    Analytic solutions are derived for flow through an elongated box-shaped aquifer that is bounded on the left, right, top and bottom sides by impermeable boundaries; the head gradient normal to the ends of the box is specified to be constant. The aquifer consists of a number of horizontal layers, each

  16. Computation of Dimensions for Strange Attractors by the Box Counting Renormalization Method

    Science.gov (United States)

    Yang, Wei-Ming; Zheng, Wei-mou

    1992-03-01

    The scaling ansats for box counting functions is verified numerically for the reverse doubling sequence of the logistic map. A box counting renormalisation method is developed to calculate dimensions for strange attractors. The project supported by National Natural Science Foundation of China.

  17. Post-training vasopressin injections may facilitate or delay shuttle-box avoidance extinction

    NARCIS (Netherlands)

    Hagan, J.J.; Bohus, B.; Wied, D. de

    1982-01-01

    After training to avoid footshock in a two-way shuttle box rats were injected with lysine vasopressin (LVP) and returned to the shuttle box 24 hr later for 10 extinction trials. Experiment 1 shows that when injected 30 min after training subsequent extinction responding varied as an inverted

  18. The Remarkably Diverse Family of T-Box Factors in Caenorhabditis elegans.

    Science.gov (United States)

    Okkema, P G

    2017-01-01

    The nematode Caenorhabditis elegans is a simple metazoan animal that is widely used as a model to understand the genetic control of development. The completely sequenced C. elegans genome contains 22 T-box genes, and they encode factors that show remarkable diversity in sequence, DNA-binding specificity, and function. Only three of the C. elegans T-box factors can be grouped into the conserved subfamilies found in other organisms, while the remaining factors are significantly diverged and unlike those in most other animals. While some of the C. elegans factors can bind canonical T-box binding elements, others bind and regulate target gene expression through distinct sequences. The nine genetically characterized T-box factors have varied functions in development and morphogenesis of muscle, hypodermal tissues, and neurons, as well as in early blastomere fate specification, cell migration, apoptosis, and sex determination, but the functions of most of the C. elegans T-box factors have not yet been extensively characterized. Like T-box factors in other animals, interaction with a Groucho-family corepressor and posttranslational SUMOylation have been shown to affect C. elegans T-box factor activity, and it is likely that additional mechanisms affecting T-box factor activity will be discovered using the effective genetic approaches in this organism. © 2017 Elsevier Inc. All rights reserved.

  19. Forkhead box transcription factors in embryonic heart development and congenital heart disease.

    Science.gov (United States)

    Zhu, Hong

    2016-01-01

    Embryonic heart development is a very complicated process regulated precisely by a network composed of many genes and signaling pathways in time and space. Forkhead box (Fox, FOX) proteins are a family of transcription factors characterized by the presence of an evolutionary conserved "forkhead"or "winged-helix" DNA-binding domain and able to organize temporal and spatial gene expression during development. They are involved in a wide variety of cellular processes, such as cell cycle progression, proliferation, differentiation, migration, metabolism and DNA damage response. An abundance of studies in model organisms and systems has established that Foxa2, Foxc1/c2, Foxh1 and Foxm1, Foxos and Foxps are important components of the signaling pathways that instruct cardiogenesis and embryonic heart development, playing paramount roles in heart development. The previous studies also have demonstrated that mutations in some of the forkhead box genes and the aberrant expression of forkhead box gene are heavily implicated in the congenital heart disease (CHD) of humans. This review primarily focuses on the current understanding of heart development regulated by forkhead box transcription factors and molecular genetic mechanisms by which forkhead box factors modulate heart development during embryogenesis and organogenesis. This review also summarizes human CHD related mutations in forkhead box genes as well as the abnormal expression of forkhead box gene, and discusses additional possible regulatory mechanisms of the forkhead box genes during embryonic heart development that warrant further investigation. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Boxenv.sty : a LATEX style file for formatting BOX expressions

    NARCIS (Netherlands)

    M. de Jonge (Merijn)

    1999-01-01

    textabstractBox is a language independent mark-up language. It is designed for use within a generic pretty-print framework to connect source language dependent front-ends to target language dependent back-ends. A front-end translates a term over a language to Box to describe its intended layout.

  1. Comparison of postbuckling model and finite element model with compression strength of corrugated boxes

    Science.gov (United States)

    Thomas J. Urbanik; Edmond P. Saliklis

    2002-01-01

    Conventional compression strength formulas for corrugated fiberboard boxes are limited to geometry and material that produce an elastic postbuckling failure. Inelastic postbuckling can occur in squatty boxes and trays, but a mechanistic rationale for unifying observed strength data is lacking. This study employs a finite element model, instead of actual experiments, to...

  2. Opening the black box of quality improvement collaboratives: An Actor-Network theory approach

    NARCIS (Netherlands)

    T. Broer (Tineke); A.P. Nieboer (Anna); R.A. Bal (Roland)

    2010-01-01

    textabstractBackground. Quality improvement collaboratives are often labeled as black boxes because effect studies usually do not describe exactly how the results were obtained. In this article we propose a way of opening such a black box, by taking up a dynamic perspective based on Actor-Network

  3. Structure and biochemical function of a prototypical Arabidopsis U-box domain

    DEFF Research Database (Denmark)

    Andersen, Pernille; Kragelund, Birthe B; Olsen, Addie N

    2004-01-01

    19p U-box and RING finger domains. In these proteins, conserved hydrophobic residues form a putative E2-binding cleft. By contrast, they contain no common polar E2 binding site motif. Two hydrophobic cores stabilize the AtPUB14 U-box fold, and hydrogen bonds and salt bridges interconnect the residues...

  4. Therapeutic Intervention in a Case of Ataxic Dysarthria Associated with a History of Amateur Boxing

    Science.gov (United States)

    McMicken, Betty L.; Ostergren, Jennifer A.; Vento-Wilson, Margaret

    2011-01-01

    The goals of this study were to (a) describe the presenting features of ataxic dysarthria present in a participant with a long history of amateur boxing, (b) describe a novel application of behavioral principles in the treatment of this participant, and (c) discuss implications in the treatment of ataxic dysarthria secondary to boxing. The…

  5. 49 CFR 215.109 - Defective plain bearing box: Journal lubrication system.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Defective plain bearing box: Journal lubrication... Freight Car Components Suspension System § 215.109 Defective plain bearing box: Journal lubrication system... impairs proper lubrication of the pad; (d) Has— (1) An exposed center core (except by design); or (2...

  6. Comparative analysis of profitability of honey production using traditional and box hives

    Directory of Open Access Journals (Sweden)

    Ahmed A. Al-Ghamdi

    2017-07-01

    Full Text Available Information on the profitability and productivity of box hives is important to encourage beekeepers to adopt the technology. However, comparative analysis of profitability and productivity of box and traditional hives is not adequately available. The study was carried out on 182 beekeepers using cross sectional survey and employing a random sampling technique. The data were analyzed using descriptive statistics, analysis of variance (ANOVA, the Cobb-Douglas (CD production function and partial budgeting. The CD production function revealed that supplementary bee feeds, labor and medication were statistically significant for both box and traditional hives. Generally, labor for bee management, supplementary feeding, and medication led to productivity differences of approximately 42.83%, 7.52%, and 5.34%, respectively, between box and traditional hives. The study indicated that productivity of box hives were 72% higher than traditional hives. The average net incomes of beekeepers using box and traditional hives were 33,699.7 SR/annum and 16,461.4 SR/annum respectively. The incremental net benefit of box hives over traditional hives was nearly double. Our study results clearly showed the importance of adoption of box hives for better productivity of the beekeeping subsector.

  7. Chaotic S-Box: Intertwining Logistic Map and Bacterial Foraging Optimization

    Directory of Open Access Journals (Sweden)

    Ye Tian

    2017-01-01

    Full Text Available As the unique nonlinear component of block ciphers, Substitution box (S-box directly affects the safety of a cryptographic system. It is important and difficult to design strong S-box that simultaneously meets multiple cryptographic criteria such as bijection, nonlinearity, strict avalanche criterion (SAC, bit independence criterion (BIC, differential probability (DP, and linear probability (LP. Though many chaotic S-boxes have been proposed, the cryptographic performance of most of them needs to be further improved. A new chaotic S-box based on the intertwining logistic map and bacterial foraging optimization is designed in this paper. It firstly iterates the intertwining logistic map to construct many S-boxes and then applies a bacterial foraging optimization algorithm to find the optimal S-box. Moreover, bacterial foraging optimization algorithm considers the nonlinearity and differential uniformity as the fitness functions in the optimization process. We experiment that the proposed S-box can effectively resist multiple types of cryptanalysis attacks.

  8. Within the Box: Cross-Cultural Art Therapy with Survivors of the Rwanda Genocide

    Science.gov (United States)

    Chu, Valerie

    2010-01-01

    This article discusses the creative making of boxes as a cross-cultural art therapy intervention in Kigali, Rwanda, with survivors of the 1994 Rwandan genocide. The box as an art form is particularly applicable with young adult survivors, given the nature of their prodigious trauma and the possibility of posttraumatic stress disorder, as well as…

  9. Nine Optical Black-Box Experiments for Lower-Secondary Students

    Science.gov (United States)

    Rode, Henning; Friege, Gunnar

    2017-01-01

    In this paper a sequence of nine, easy to manufacture optical black-box experiments with increasing levels of difficulty, and supportive frameworks for physics classes are introduced. They have been evaluated in a lower-secondary school at the end of optics lessons. A black-box is a kind of experimental task where the inner structure is not…

  10. Allowing New Opportunities in Advanced Laparoscopy Training Using a Full High-Definition Training Box.

    Science.gov (United States)

    Achurra, Pablo; Lagos, Antonia; Avila, Ruben; Tejos, Rodrigo; Buckel, Erwin; Alvarado, Juan; Boza, Camilo; Jarufe, Nicolas; Varas, Julian

    2017-02-01

    Simulated laparoscopy training is limited by its low-quality image. A high-definition (HD) laparoscopic training box was developed under the present necessity of simulating advanced surgery. To describe and test a new HD laparoscopic training box for advanced simulation training. We describe the features and image quality of the new training box. The simulator was tested and then evaluated by a group of 76 expert surgeons using a 4-item questionnaire. To assess the effectiveness of training using this simulation box, 15 general surgery residents were trained to perform a laparoscopic jejuno-jejunostomy in a validated simulation program. They were assessed with objective rating scales before and after the training program, and their results were compared with that of experts. The training box was assembled using high-density fiberglass shaped as an insufflated abdomen. It has an adapted full-HD camera with a LED-based illumination system. A manually self-regulated monopod attached to the camera enables training without assistance. Of the expert surgeons who answered the questionnaire, 91% said that the simulation box had a high-quality image and that it was very similar to real laparoscopy. All residents trained improved their rating scores significantly when comparing their initial versus final assessment ( P .2). This novel laparoscopic training box presents a high-resolution image and allows training different types of advanced laparoscopic procedures. The simulator box was positively assessed by experts and demonstrated to be effective for laparoscopy training in resident surgeons.

  11. Transcriptome analysis uncovers Arabidopsis F-BOX STRESS INDUCED 1 as a regulator of jasmonic acid and abscisic acid stress gene expression.

    Science.gov (United States)

    Gonzalez, Lauren E; Keller, Kristen; Chan, Karen X; Gessel, Megan M; Thines, Bryan C

    2017-07-17

    The ubiquitin 26S proteasome system (UPS) selectively degrades cellular proteins, which results in physiological changes to eukaryotic cells. F-box proteins are substrate adaptors within the UPS and are responsible for the diversity of potential protein targets. Plant genomes are enriched in F-box genes, but the vast majority of these have unknown roles. This work investigated the Arabidopsis F-box gene F-BOX STRESS INDUCED 1 (FBS1) for its effects on gene expression in order elucidate its previously unknown biological function. Using publically available Affymetrix ATH1 microarray data, we show that FBS1 is significantly co-expressed in abiotic stresses with other well-characterized stress response genes, including important stress-related transcriptional regulators. This gene suite is most highly expressed in roots under cold and salt stresses. Transcriptome analysis of fbs1-1 knock-out plants grown at a chilling temperature shows that hundreds of genes require FBS1 for appropriate expression, and that these genes are enriched in those having roles in both abiotic and biotic stress responses. Based on both this genome-wide expression data set and quantitative real-time PCR (qPCR) analysis, it is apparent that FBS1 is required for elevated expression of many jasmonic acid (JA) genes that have established roles in combatting environmental stresses, and that it also controls a subset of JA biosynthesis genes. FBS1 also significantly impacts abscisic acid (ABA) regulated genes, but this interaction is more complex, as FBS1 has both positive and negative effects on ABA-inducible and ABA-repressible gene modules. One noteworthy effect of FBS1 on ABA-related stress processes, however, is the restraint it imposes on the expression of multiple class I LIPID TRANSFER PROTEIN (LTP) gene family members that have demonstrated protective effects in water deficit-related stresses. FBS1 impacts plant stress responses by regulating hundreds of genes that respond to the plant

  12. Impact Characteristic According to the Structure of Crash Box at the Vehicle

    Directory of Open Access Journals (Sweden)

    Min B.S.

    2017-06-01

    Full Text Available The crash box between a bumper and a car body in automobiles can reduce impacts for car bodies with a bumper at a low-speed collision by preventing the shocks. Also, this crash box is the part playing a very important role for the safety of vehicle and the reduction of repair cost, and many studies have been investigated for the performance. In this study, aluminum foam was inserted in an aluminum crash box to analyze the relationships of deformation, stress and internal energy. The compression characteristics are compared with six cases. In addition, the load due to displacement at experiment for a case is verified by modeling with finite elements and performing the structural analysis. As these study results for investigating characteristics of the crash box, it is thought that the effective designs of crash box to enhance the durability for collision are made possible.

  13. Augmented twin-nonlinear two-box behavioral models for multicarrier LTE power amplifiers.

    Science.gov (United States)

    Hammi, Oualid

    2014-01-01

    A novel class of behavioral models is proposed for LTE-driven Doherty power amplifiers with strong memory effects. The proposed models, labeled augmented twin-nonlinear two-box models, are built by cascading a highly nonlinear memoryless function with a mildly nonlinear memory polynomial with cross terms. Experimental validation on gallium nitride based Doherty power amplifiers illustrates the accuracy enhancement and complexity reduction achieved by the proposed models. When strong memory effects are observed, the augmented twin-nonlinear two-box models can improve the normalized mean square error by up to 3 dB for the same number of coefficients when compared to state-of-the-art twin-nonlinear two-box models. Furthermore, the augmented twin-nonlinear two-box models lead to the same performance as previously reported twin-nonlinear two-box models while requiring up to 80% less coefficients.

  14. Roof Box Shape Streamline Adaptation and the Impact towards Fuel Consumption

    Directory of Open Access Journals (Sweden)

    Abdul Latif M.F.

    2017-01-01

    Full Text Available The fuel price hike is currently a sensational national issue in Malaysia. Since the rationalization of fuel subsidies many were affected especially the middle income family. Vehicle aerodynamic were directly related to the fuel consumption, were extra frontal area result a higher drag force hence higher fuel consumption. Roof box were among the largest contributor to the extra drag, thus the roof box shape rationalization were prominent to reduce the extra drag. The idea of adopting water drop shape to the roof box design shows prominent result. The roof box has been simulated using MIRA virtual wind tunnel modelling via commercial computational fluid dynamic (CFD package. This streamline shape drastically reduce the drag force by 34% resulting to a 1.7% fuel saving compare to the conventional boxy roof box. This is an effort to reduce the carbon foot print for a sustainable green world.

  15. Generalized Majority Logic Criterion to Analyze the Statistical Strength of S-Boxes

    Science.gov (United States)

    Hussain, Iqtadar; Shah, Tariq; Gondal, Muhammad Asif; Mahmood, Hasan

    2012-05-01

    The majority logic criterion is applicable in the evaluation process of substitution boxes used in the advanced encryption standard (AES). The performance of modified or advanced substitution boxes is predicted by processing the results of statistical analysis by the majority logic criteria. In this paper, we use the majority logic criteria to analyze some popular and prevailing substitution boxes used in encryption processes. In particular, the majority logic criterion is applied to AES, affine power affine (APA), Gray, Lui J, residue prime, S8 AES, Skipjack, and Xyi substitution boxes. The majority logic criterion is further extended into a generalized majority logic criterion which has a broader spectrum of analyzing the effectiveness of substitution boxes in image encryption applications. The integral components of the statistical analyses used for the generalized majority logic criterion are derived from results of entropy analysis, contrast analysis, correlation analysis, homogeneity analysis, energy analysis, and mean of absolute deviation (MAD) analysis.

  16. Heating Processes Of The Axle-Boxes Of Rolling-Stock On Railway Track Curves

    Directory of Open Access Journals (Sweden)

    Olegas Lunys

    2013-12-01

    Full Text Available The article deals with the heating process of the axle-boxes ofrolling stock when the train is in motion and discusses the forcesacting on the wheel-set when rolling stock moves along the trackcurves. The paper analyses scientific publications relevant tothe forces acting on the wheel-set of rolling stock and focuseson the axle-box heating process. The article also discusses theresults of theoretical studies on wheel-set forces that affect theheat exchange process of axle-boxes for a railway vehicle. Theresearch has determined a change in heating temperatures ofdifferent axle-boxes of rolling stock and reasons for their variationsand tendencies. The paper has estimated an effect of thetrain running along the track curves on the heating intensity ofthe axle-box. Finally, valid conclusions and recommendationshave been provided.

  17. Design and test of box girder for a large wind turbine blade

    DEFF Research Database (Denmark)

    Nielsen, Per Hørlyk; Tesauro, Angelo; Bitsche, Robert

    This report is covering the structural design and full scale test of a box girder as a part of the project “Demonstration of new blade design using manufacturing process simulations” supported by the EUDP program. A box girder with a predetermined outer geometry was designed using new inventions......, which create an inner structure in the box girder. With a combination of advanced FEM analysis and the inventions it was possible to reduce the material thickness of the cap by up to 40%. The new design of the box girder was manufactured at SSP Technology A/S, where it was demonstrated...... that the manufacturing process could include the new inventions. Subsequently the box girder was transported to the blade test facility at DTU Wind Energy. A series of test was performed with the blade to investigate the behaviour during loading, and finally the girder was loaded to ultimate failure. The report includes...

  18. Augmented Twin-Nonlinear Two-Box Behavioral Models for Multicarrier LTE Power Amplifiers

    Directory of Open Access Journals (Sweden)

    Oualid Hammi

    2014-01-01

    Full Text Available A novel class of behavioral models is proposed for LTE-driven Doherty power amplifiers with strong memory effects. The proposed models, labeled augmented twin-nonlinear two-box models, are built by cascading a highly nonlinear memoryless function with a mildly nonlinear memory polynomial with cross terms. Experimental validation on gallium nitride based Doherty power amplifiers illustrates the accuracy enhancement and complexity reduction achieved by the proposed models. When strong memory effects are observed, the augmented twin-nonlinear two-box models can improve the normalized mean square error by up to 3 dB for the same number of coefficients when compared to state-of-the-art twin-nonlinear two-box models. Furthermore, the augmented twin-nonlinear two-box models lead to the same performance as previously reported twin-nonlinear two-box models while requiring up to 80% less coefficients.

  19. Inhibition of forkhead boxO-specific transcription prevents mechanical ventilation-induced diaphragm dysfunction.

    Science.gov (United States)

    Smuder, Ashley J; Sollanek, Kurt J; Min, Kisuk; Nelson, W Bradley; Powers, Scott K

    2015-05-01

    Mechanical ventilation is a lifesaving measure for patients with respiratory failure. However, prolonged mechanical ventilation results in diaphragm weakness, which contributes to problems in weaning from the ventilator. Therefore, identifying the signaling pathways responsible for mechanical ventilation-induced diaphragm weakness is essential to developing effective countermeasures to combat this important problem. In this regard, the forkhead boxO family of transcription factors is activated in the diaphragm during mechanical ventilation, and forkhead boxO-specific transcription can lead to enhanced proteolysis and muscle protein breakdown. Currently, the role that forkhead boxO activation plays in the development of mechanical ventilation-induced diaphragm weakness remains unknown. This study tested the hypothesis that mechanical ventilation-induced increases in forkhead boxO signaling contribute to ventilator-induced diaphragm weakness. University research laboratory. Young adult female Sprague-Dawley rats. Cause and effect was determined by inhibiting the activation of forkhead boxO in the rat diaphragm through the use of a dominant-negative forkhead boxO adeno-associated virus vector delivered directly to the diaphragm. Our results demonstrate that prolonged (12 hr) mechanical ventilation results in a significant decrease in both diaphragm muscle fiber size and diaphragm-specific force production. However, mechanically ventilated animals treated with dominant-negative forkhead boxO showed a significant attenuation of both diaphragm atrophy and contractile dysfunction. In addition, inhibiting forkhead boxO transcription attenuated the mechanical ventilation-induced activation of the ubiquitin-proteasome system, the autophagy/lysosomal system, and caspase-3. Forkhead boxO is necessary for the activation of key proteolytic systems essential for mechanical ventilation-induced diaphragm atrophy and contractile dysfunction. Collectively, these results suggest that

  20. View of the inner part of the VO prototype box. The WLS fibers wrapped up in teflon strips are coupled to connectors which ensure the passage of the light outside the box and its transfer in optical fibers.

    CERN Document Server

    2004-01-01

    View of the inner part of the VO prototype box. The WLS fibers wrapped up in teflon strips are coupled to connectors which ensure the passage of the light outside the box and its transfer in optical fibers.