WorldWideScience

Sample records for botucatu eye study

  1. Comparative study between Botucatu and Berea sandstone properties

    Science.gov (United States)

    Cardoso, Oldemar Ribeiro; Balaban, Rosangela de Carvalho

    2015-10-01

    The aim of the present study is the analysis and comparison between Berea and Botucatu sandstone, concerning the problems with regard to the loss of permeability or water sensitivity or loss of hydraulic conductivity due to the presence of swelling or non-swelling clays. Some porous volumes of synthetic seawater of different salinities were displaced through the porous media of Berea and Botucatu formations. It was observed that even the plugs of Berea, with no-swelling clays in their composition, had the permeability reduced as soon as the brine salinity reached a lower limit. As expected, the same occurred with the Botucatu sandstone samples, however, in this case,the sensitivity to the low salinity was much more effective.

  2. Use of thorium as tracer on study of groundwater of Botucatu sandstone

    Energy Technology Data Exchange (ETDEWEB)

    Porto, Paulo Augusto d' A.; Menezes, Maria Angela B.C. de; Moreira, Rubens Martins; Reis Junior, Aluisio Souza; Kastner, Geraldo Frederico, E-mail: paap@cdtn.br, E-mail: menezes@cdtn.br, E-mail: rubens@cdtn.br, E-mail: reisas@cdtn.br, E-mail: gfk@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2013-07-01

    Thorium in some mineral compounds is very difficult to be dissolved in aqueous medium. To study the mobility of thorium in water, one alternative is to complex this element with EDTA, becoming possible to follow the behavior of thorium this medium. This way, in groundwater with low natural radioactivity and low {sup 232}Th activity, thorium can be used as a tracer. This paper describes the application of the complex Th-EDTA as a tracer applying the solution trough a sandstone sample made by rock from Botucatu Sandstone. The objective was to simulate the flow of groundwater inside the original rock aiming at future use of rare-earth elements complexed with EDTA as tracer. Alpha spectrometry technique was used to determine {sup 232}Th in the water samples with {sup 230}Th as inner-standard. (author)

  3. Tick fever in cattle in the region of Botucatu - SP: a retrospective study of 1986-2007/ Tristeza Parasitária em bovinos na região de Botucatu – SP: estudo retrospectivo de 1986 – 2007

    Directory of Open Access Journals (Sweden)

    Alexandre Secorum Borges

    Full Text Available A retrospective study of Cattle Tick Fever was made with animals up to one year old, which occurred from 1986-2007 in Botucatu-SP in the influence area of the Veterinary Hospital of the School of Veterinary Medicine and Animal Science – UNESP. There were 232 cases and 57 deaths. The main etiological agent causing the disease on this region is Anaplasma marginale identified as a single agent in 31.5% of the cases. Most of the cases occurred on autumn in mixed-blood animals two to six months old. Predominant clinical signs included apathy, hyporexia or anorexia, dehydration, weight loss and pale mucosa. The high incidence and mortality observed justify prophylactic actions to have the balance between host, agent, vector, and environment, thus avoiding the clinical form of disease and death of livestock herds in the region.Foi realizado um estudo retrospectivo dos casos de tristeza parasitária bovina (TPB em bovinos com até um ano de idade ocorridos na região de Botucatu-SP, área de influência do Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia de Botucatu – UNESP, entre os anos de 1986 e 2007. Ocorreram, nesse período, 232 casos da doença e 57 mortes. O principal agente etiológico causador da doença nesta região foi o Anaplasma marginale, identificado como um único agente em 31,5% dos episódios da doença. A maioria dos casos ocorreu no Outono, em animais mestiços e com dois a seis meses de idade. Os sinais clínicos predominantes foram: apatia, hiporexia ou anorexia, desidratação, perda de peso e palidez das mucosas. A elevada incidência e mortalidade observados justificam ações profiláticas visando o equilíbrio entre hospedeiro, agente, vetor, e meio ambiente, evitando, assim, a forma clínica da doença e morte dos animais em rebanhos da região.

  4. Sensoriamento remoto e geoprocessamento aplicados ao uso da terra em microbacias hidrográficas, Botucatu - SP Remote sensing and gis applied to study the land use in watersheds in Botucatu, Brazil

    Directory of Open Access Journals (Sweden)

    Sérgio Campos

    2004-08-01

    Full Text Available O presente trabalho teve como objetivo identificar e quantificar o uso da terra em dez microbacias ocorrentes na bacia do Rio Capivara, município de Botucatu - SP, a partir da estruturação de um banco de dados utilizando o Sistema de Informações Geográficas (SIG - IDRISI. Os resultados mostram que as classes de uso da terra, "uso agrícola" e "pastagem", foram as mais significativas, pois ocuparam mais da metade da área das microbacias. O alto índice de uso da terra por pastagens, capoeiras, reflorestamento e matas reflete a predominância de solos arenosos com baixa fertilidade. As imagens obtidas do satélite LANDSAT 5 permitiram o mapeamento do uso da terra de maneira rápida, além de fornecer um excelente banco de dados para futuro planejamento e gerenciamento das atividades agropecuárias regionais. O SIG-IDRISI permitiu identificar, por meio de seus diferentes módulos para georreferenciamento, classificação digital e modelo matemático, as classes de uso da terra com rapidez.This study aimed to identify and quantify the land use in ten watersheds in the Capivara river-basin, in the municipality of Botucatu - SP, Brazil. A database was made using the Geographical Information System - IDRISI. The results showed that the classes of agriculture and pasture were the most significant land use, as they occupied more than half of the area of the watersheds. The high index of land use by pasture, brushwood, reforestation and forests, reflected the predominance of sandy soils with low fertility. The images of the satellite LANDSAT-5 allowed the mapping of the land use in a fast and reliable way. In addition they supplied an excellent database for future planning and management of the regional agricultural activities. GIS - IDRISI allowed the identification, digital classification and mathematical modeling of several areas of land use.

  5. Estudo de sobrevivência de uma coorte de pessoas de 60 anos e mais no município de Botucatu (SP - Brasil Survival study of a sixty year-old and older cohort in Botucatu (SP - Brazil

    Directory of Open Access Journals (Sweden)

    Tania Ruiz

    2003-09-01

    Full Text Available O aumento proporcional do número de idosos na população tem motivado estudos no sentido de melhorar a qualidade de vida desta faixa etária através de políticas sociais e, entre elas, o planejamento em saúde. Com o objetivo de conhecer riscos de mortalidade para a população de sessenta anos e mais, um estudo de sobrevida foi realizado rastreando, no ano de 1992, os idosos participantes de um inquérito de morbidade referida realizado na cidade de Botucatu em 1983/84. Foram localizados 89,6% destes idosos. Curvas de sobrevivência foram calculadas com o método de Kaplan-Meier e a análise de riscos, utilizando-se a Regressão Múltipla de Cox ajustando-se o modelo agregando as variáveis por blocos. Para o sexo masculino foram encontradas associadas, independentemente, ao aumento da mortalidade as seguintes categorias de variáveis: idade de 70 anos e mais: Hazard Ratio (HR=2,4 (1,6 - 3,7; salário menor que um salário mínimo: HR=2,2 (1,3 - 3,8; ter "outras rendas": HR=2,2 (1,3 - 3,9; ser o chefe da família ou seu cônjuge: HR=2,3 (1,2 - 2,4; referência de doenças do aparelho circulatório: HR=1,6 (1,1 - 2,4; referência de diabetes mellitus: HR=3,0 (1,3 - 7,0. Para o sexo feminino, foram encontradas associadas a idade de 70 anos e mais: HR=4,6 (3,0 - 7,1; referência de diabetes mellitus: HR=3,0 (1,7-5,3 e ter "outras rendas": HR=2,0 (1,1 - 4,0.In order to determine mortality predictors among individuals aged 60 years and over, a survival study was conducted in 1992 by tracking a population of elders who participated in a general self-rated morbidity survey in 1983/84, in Botucatu, SP - Brazil. Kaplan-Meier estimates and the Cox proportional hazards method, available in SPSS and SAS statistical packages (v. 6.12, were used to analyze survival. The following mortality predictors were found for males (p<0.05: being 70 years or older: Hazard Ratio (HR=2.4 (1.6 - 3.7; earning one or less than one minimum wage: HR=2.2 (1.3 - 3.8; having

  6. Danish Rural Eye Study

    DEFF Research Database (Denmark)

    Høeg, Tracy B; Moldow, Birgitte; Ellervik, Christina;

    2015-01-01

    PURPOSE: To determine the prevalence of amblyopia in Denmark before and after the initiation of the Danish national preschool vision screening programme. METHODS: In a population-based cross-sectional study, 3826 participants of the Danish General Suburban Population Study (GESUS) aged 20 years...... and older from a Danish rural municipality received a complete general health examination and an ophthalmological interview and examination. This study included a comprehensive ophthalmologic interview, measurement of best corrected visual acuity (BCVA) in each eye, Hirschberg's test for strabismus and two...... 45-degree retinal fundus photographs of each eye. A complete ophthalmologic examination was performed when indicated. RESULTS: The prevalence of monocular visual impairment (MVI) was 4.26% (95% CI, 3.66-4.95, n = 163). Amblyopia was the most common cause, accounting for 33%. The prevalence...

  7. Clinical, cytogenetic and toxicological studies in rural workers exposed to pesticides in Botucatu, São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Salete Marcia Bréga

    1998-01-01

    Full Text Available Pesticides can cause gene mutations and chromosomal aberrations in exposed individuals. We have investigated 24 workers exposed to pesticides. Clinical examinations and cytogenetic and toxicological tests were performed. Ten non-exposed individuals were used as controls. Toxicological dosages of copper, zinc and manganese (metals found in some pesticides, hepatic enzyme dosage (GOT, GPT, AR and acetylcholinesterase activity were performed in 16 workers and 8 controls. In the exposed workers, the most relevant clinical symptoms were poor digestion with fullness sensation after meals, irritated eyes, headache and fasciculations. The exposed group showed significantly lower manganese dosage and acetylcholinesterase activity, and significantly higher levels of alkaline phosphatase. Cytogenetic studies showed significantly higher chromosomal aberrations in the exposed group compared to the control group. Although the workers used protection against the pesticide's fog, the results revealed that the workers were contaminated with the pesticides. Therefore, the cytogenetic, toxicological studies with clinical examination are necessary for monitoring workers who are exposed to pesticides in any situation.

  8. Tromsø eye study

    DEFF Research Database (Denmark)

    Bertelsen, Geir; Peto, Tunde; Lindekleiv, Haakon;

    2013-01-01

    Purpose:  To determine the prevalence of visual impairment, retinopathy and macular oedema, and assess risk factors for retinopathy in persons with diabetes. Methods:  The present study included 514 participants with diabetes aged 46-87 years from the Tromsø Eye Study, a sub-study of the population......-based Tromsø Study in Norway. Visual acuity was measured using an auto-refractor. Retinal images from both eyes were graded for retinopathy and macular oedema. We collected data on risk factor exposure from self-report questionnaires, clinical examinations, laboratory measurements and case note reviews....... Regression models assessed the cross-sectional relationship between potential risk factors and diabetic retinopathy. Results:  The prevalence of visual impairment (corrected Snellen visual acuity...

  9. Prevalence of brain atrophy in dogs submitted to cranial tomography in FMVZ - UNESP Botucatu: retrospective study; Prevalencia de atrofia cerebral em caes submetidos a tomografia craniana na FMVZ - UNESP Botucatu: estudo retrospectivo

    Energy Technology Data Exchange (ETDEWEB)

    Babicsak, Viviam Rocco; Belotta, Alexandra Frey; Oliveira, Hugo Salvador de; Zardo, Karen Maciel; Santos, Debora Rodrigues dos; Mamprim, Maria Jaqueline; Machado, Vania Maria de Vasconcelos; Vulcano, Luiz Carlos, E-mail: viviam.babicsak@gmail.com [Universidade Estadual Paulista Julio de Mesquita Filho (FMVZ/UNESP), Botucatu, SP (Brazil). Faculdade de Medicina Veterinaria e Zootecnia . Dept. de Reproducao Animal e Radiologia Veterinaria

    2012-07-01

    Brain atrophy is diagnosed by imaging methods that allow the verification of the widening of cerebral sulci and ventricular dilatation. In this retrospective study, in which the cranial CT scans of 150 dogs were evaluated, brain atrophy was identified in 16 animals. Mixed breed dogs were the most affected, followed by poodles, maltese, dachshunds, yorkshires, pinschers and cockers. Brain atrophy was observed in animals of all age groups, being more prevalent in middle aged dogs followed by elderly animals, in which this alteration can be commonly found. The identification of reduced brain volume, however, may not be the cause of neurological signs expressed by animals since in some dogs of this study it was considered a finding. (author)

  10. Retrospective study of ear findings of dogs submitted to cranial tomography in FMVZ - UNESP, Botucatu; Estudo retrospectivo dos achados otologicos de caes submetidos a tomografia craniana na FMVZ - UNESP, Botucatu

    Energy Technology Data Exchange (ETDEWEB)

    Babicsak, Viviam Rocco; Oliveira, Hugo Salvador de; Belotta, Alexandra Frey; Santos, Debora Rodrigues dos; Zardo, Karen Maciel; Mamprim, Maria Jaqueline; Machado, Vania Maria de Vasconcelos; Vulcano, Luiz Carlos, E-mail: viviam.babicsak@gmail.com [Universidade Estadual Paulista Julio de Mesquita Filho (FMVZ/UNESP), Botucatu, SP (Brazil). Faculdade de Medicina Veterinaria e Zootecnia. Dept. de Reproducao Animal e Radiologia Veterinaria

    2012-07-01

    Computed tomography (CT) is an important imaging modality in the diagnosis of ear alterations, especially those affecting the middle ear. In this retrospective study, in which the cranial CT scans of 151 dogs were evaluated, the most common finding was the mineralization of the external auditory cartilage, followed by secretions in external and middle ear and tissue in these two regions. The average age of affected animals ranged from 6-9 years. Mixed breed dogs were the most affected animals, followed by cockers, boxers, poodles, labrador retrievers, german shepherds and pit bulls. (author)

  11. The Tromsø Eye Study

    DEFF Research Database (Denmark)

    Bertelsen, Geir; Erke, Maja G; von Hanno, Therese;

    2013-01-01

    Purpose:  To describe the study design and methodology of the Tromsø Eye Study (TES), and to describe visual acuity and refractive error in the study population. Methods:  The Tromsø Eye Study is a sub-study of the Tromsø Study, a population-based multipurpose longitudinal study in the municipality...... of Tromsø, Norway. The Tromsø Eye Study was a part of the sixth survey of the Tromsø Study, conducted from October 2007 through December 2008. The eye examination included information on self-reported eye diseases, assessment of visual acuity and refractive errors, retinal photography and optical coherence......, carotid artery ultrasound, electrocardiogram, bone densitometry, cognitive tests, questionnaires, DNA, blood and urine samples and more from the present and the five previous surveys. Results:  Visual acuity was assessed in 6459 subjects and refraction in 6566 subjects aged 38-87 years. Snellen visual...

  12. The Tehran Eye Study: research design and eye examination protocol

    Directory of Open Access Journals (Sweden)

    Fotouhi Akbar

    2003-07-01

    Full Text Available Abstract Background Visual impairment has a profound impact on society. The majority of visually impaired people live in developing countries, and since most disorders leading to visual impairment are preventable or curable, their control is a priority in these countries. Considering the complicated epidemiology of visual impairment and the wide variety of factors involved, region specific intervention strategies are required for every community. Therefore, providing appropriate data is one of the first steps in these communities, as it is in Iran. The objectives of this study are to describe the prevalence and causes of visual impairment in the population of Tehran city; the prevalence of refractive errors, lens opacity, ocular hypertension, and color blindness in this population, and also the familial aggregation of refractive errors, lens opacity, ocular hypertension, and color blindness within the study sample. Methods Design Through a population-based, cross-sectional study, a total of 5300 Tehran citizens will be selected from 160 clusters using a stratified cluster random sampling strategy. The eligible people will be enumerated through a door-to-door household survey in the selected clusters and will be invited. All participants will be transferred to a clinic for measurements of uncorrected, best corrected and presenting visual acuity; manifest, subjective and cycloplegic refraction; color vision test; Goldmann applanation tonometry; examination of the external eye, anterior segment, media, and fundus; and an interview about demographic characteristics and history of eye diseases, eye trauma, diabetes mellitus, high blood pressure, and ophthalmologic cares. The study design and eye examination protocol are described. Conclusion We expect that findings from the TES will show the status of visual problems and their causes in the community. This study can highlight the people who should be targeted by visual impairment prevention programs.

  13. Estudo com gestantes atendidas em um centro municipal de saúde da periferia de Botucatu - São Paulo: relação entre baixo peso materno e baixo peso ao nascer do concepto Estudio con gestantes atendidas en un centro municipal de salud de los alrededores de Botucatu - São Paulo: relación entre bajo peso materno y bajo peso al nacer del concepto Study of pregnant women at a city health center in Botucatu, São Paulo: relationship of low maternal weight and low birth weight

    Directory of Open Access Journals (Sweden)

    Cristina Maria Garcia de Lima

    1995-01-01

    .This study evaluated a group of 15 low-weight pregnant women, who underwent prenatal medical examinations at a City Health Center on the outskirts of Botucatu - SP, using the "Rosso Curve", and compared them with a group of 8 normal-weight pregnant women, also screened by the same institution at the same prenatal service. We verified that the children born from normal-weight pregnant women weighed an average 118g more than those of low-weight pregnant women. Independent of the mother's weight, those born from mothers whose height was greater than 155cm and were non-smokers weighed more. Pregnant women of normal weight had, on average, an additional 2 weeks of pregnancy: Amongst those born of low-weight pregnant women, we noted a connection between medium birth weight and an increase on the uterine height curve x gestational age. There was no connection between maternal anemia and interpartal intervals less than to 2 years and birth weight.

  14. Viewpoint Consistency: An Eye Movement Study

    Directory of Open Access Journals (Sweden)

    Filipe Cristino

    2012-05-01

    Full Text Available Eye movements have been widely studied, using images and videos in laboratories or portable eye trackers in the real world. Although a good understanding of the saccadic system and extensive models of gaze have been developed over the years, only a few studies have focused on the consistency of eye movements across viewpoints. We have developed a new technique to compute and map the depth of collected eye movements on stimuli rendered from 3D mesh objects using a traditional corneal reflection eye tracker (SR Eyelink 1000. Having eye movements mapped into 3D space (and not on an image space allowed us to compare fixations across viewpoints. Fixation sequences (scanpaths were also studied across viewpoints using the ScanMatch method (Cristino et al 2010, Behavioural and Research Methods 42, 692–700, extended to work with 3D eye movements. In a set of experiments where participants were asked to perform a recognition task on either a set of objects or faces, we recorded their gaze while performing the task. Participants either viewed the stimuli in 2D or using anaglyph glasses. The stimuli were shown from different viewpoints during the learning and testing phases. A high degree of gaze consistency was found across the different viewpoints, particularly between learning and testing phases. Scanpaths were also similar across viewpoints, suggesting not only that the gazed spatial locations are alike, but also their temporal order.

  15. Zika Found in Eye Fluid in Study

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_160986.html Zika Found in Eye Fluid in Study Virus may ... 15, 2016 THURSDAY, Sept. 15, 2016 (HealthDay News) -- Zika can be detected in fluid inside the eyelid ...

  16. A study of artificial eyes for the measurement of precision in eye-trackers.

    Science.gov (United States)

    Wang, Dong; Mulvey, Fiona B; Pelz, Jeff B; Holmqvist, Kenneth

    2016-07-06

    The precision of an eye-tracker is critical to the correct identification of eye movements and their properties. To measure a system's precision, artificial eyes (AEs) are often used, to exclude eye movements influencing the measurements. A possible issue, however, is that it is virtually impossible to construct AEs with sufficient complexity to fully represent the human eye. To examine the consequences of this limitation, we tested currently used AEs from three manufacturers of eye-trackers and compared them to a more complex model, using 12 commercial eye-trackers. Because precision can be measured in various ways, we compared different metrics in the spatial domain and analyzed the power-spectral densities in the frequency domain. To assess how precision measurements compare in artificial and human eyes, we also measured precision using human recordings on the same eye-trackers. Our results show that the modified eye model presented can cope with all eye-trackers tested and acts as a promising candidate for further development of a set of AEs with varying pupil size and pupil-iris contrast. The spectral analysis of both the AE and human data revealed that human eye data have different frequencies that likely reflect the physiological characteristics of human eye movements. We also report the effects of sample selection methods for precision calculations. This study is part of the EMRA/COGAIN Eye Data Quality Standardization Project.

  17. Post-destructive eye surgery, associated depression at Sekuru Kaguvi Hospital Eye Unit, Zimbabwe: Pilot Study

    Directory of Open Access Journals (Sweden)

    M. M. Kawome

    2013-12-01

    Full Text Available Destructive eye surgery is associated with more complications than just loss of visual functions of the eye and aesthetics. Currently there is very little published literature on post-destructive eye surgery associated depression. Zimbabwe has been experiencing a surge in the rate of destructive eye surgery done at the National Tertiary Eye Unit. This situation could be churning out lots of unrecognized depressed clients into the community who require assistance in one form or another.Objectives: To determine the prevalence of post-destructive eye surgery associated depression among patients attending Sekuru Kaguvi Hospital Eye Unit and assess if the current management protocol of patients undergoing destructive eye surgery at the Eye Unit addresses the problem adequately.Methods: A cross-sectional study of 28 randomly selected patients who had destructive eye surgeries at Sekuru Kaguvi Hospital was conducted over five months from 1st March 2012 to end of July 2012. A structured questionnaire containing 15 questions on the following items: gender, age, diagnosis, surgical procedure done, expectations before and after surgery, adequacy of counseling given and involvement of family was used to collect data. Nine questions to assess depression were adapted from the Patient Health Questionnaire (PHQ-9.Setting:  The study was conducted at SekuruKaguvi Hospital Eye Unit, Parirenyatwa Group of Hospitals in Harare.Results:  Twenty-eight patients who underwent destructive eye surgery during the study period were selected using systematic random sampling. The gender ratio was 1:1 and the mean age was 38.7 years with a range from 24 to 65 years. Fifty percent of the patients in the study had orbital exenteration while the rest had enucleation (14% and evisceration (36%. Twenty-eight percent of the study population had depression.Conclusion: Destructive eye surgery is frequently associated with depression and our current management protocol of patients

  18. Estudo comparativo da pressão arterial e da prevalência de hipertensão arterial em duas coortes sucessivas (1975-1976 de estudantes de 16 a 25 anos, Botucatu, SP, Brasil Blood pressure levels and hipertension prevalence in 16 to 25 year-old students in Botucatu, S. Paulo, Brazil. A comparative study of two successive cohorts, 1975-1976

    Directory of Open Access Journals (Sweden)

    Dináh Borges de Almeida

    1978-12-01

    Full Text Available Com o objetivo de determinar os níveis de pressão arterial e a prevalência de hipertensão arterial em uma população jovem, foram realizados pesquisas em dois anos sucessivos em 1.288 e 736 estudantes de Botucatu, SP (Brasil tendo sido comparados os resultados obtidos. As médias das pressões sistólicas da população estudada e dos dois grupos etários desta população (16 a 20 anos e 21 a 25 anos foram idênticas em ambos os anos, tendo as médias das pressões diastólicas diferido de no máximo 2 mmHg; as médias, tanto sistólicas quanto diastólicas, dos dois sexos e da parcela branca da população estudada quanto à idade e sexo também diferiram de no máximo 2 mmHg. As médias da população estudada e sua parcela branca, em ambos os anos, foram superiores no sexo masculino e no grupo etário de 21 a 25 anos. Na população negra e amarela houve disparidade de resultados entre 1975 e 1976, indicando influência da exiguidade do tamanho dos contigentes negro e amarelo desta população. A prevalência de hipertensão arterial (pressão sistólica igual ou maior que 140 mmHg e diastólica igual ou maior que 90 mmHg foi de 5,04% em 1975 e 6,22% em 1976, tendo sido em ambos os anos maior no sexo masculino do que no feminino e no grupo de 21 a 25 do que no de 16 a 20 anos.To determine the prevalence of hypertension and blood pressure levels in a young population group, two groups, one of 1288 students and another of 736, all from Botucatu, were investigated during two consecutive years, and the results were then compared. The mean values for systolic readings of the whole population, as for the two age groups (16 to 20 and 21 to 25 years old, were identical for both years studied; the diastolic mean values differed by 2 mmHg at most. The mean systolic and diastolic reading for both sexes and among the whites also differed by 2 mmHg at most. The mean values for the whole population and among the white population were higher for males

  19. Cohort profile: Shahroud Eye Cohort Study.

    Science.gov (United States)

    Fotouhi, Akbar; Hashemi, Hassan; Shariati, Mohammad; Emamian, Mohammad Hassan; Yazdani, Kamran; Jafarzadehpur, Ebrahim; Koohian, Hassan; Khademi, Mohammad Reza; Hodjatjalali, Kamran; Kheirkhah, Ahmad; Chaman, Reza; Malihi, Sarvenaz; Mirzaii, Mehdi; Khabazkhoob, Mehdi

    2013-10-01

    The Shahroud Eye Cohort Study was set up to determine the prevalence and incidence of visual impairment and major eye conditions in the 40-64-year-old population of Shahroud as a Middle Eastern population. The first phase of the study was conducted in 2009-10. Using random cluster sampling, 6311 Shahroud inhabitants were invited for ophthalmologic examinations; of these, 5190 participants completed phase 1 (participation rate of 82.2%). All participants were interviewed to collect data on participants' demographics, occupation status, socioeconomic status, history of smoking, and medical and ophthalmic history, as well as history of medication, and the quality and duration of their insurance. DNA and plasma samples, as well as four dots of whole blood were collected from participants. Extensive optometric and ophthalmologic examinations were performed for each participant, including lensometry of current glasses, testing near and far visual acuity; determining objective and subjective refraction; eye motility; cycloplegic refraction; colour vision test; slit-lamp biomicroscopy and intraocular pressure measurement; direct and indirect fundoscopy; perimetry test; ocular biometry; corneal topography; lens and fundus photography; and the Schirmer's (1008 participants) and tear breakup time tests (1013 participants). The study data are available for collaborative research at Noor Ophthalmology Research Center, Tehran, Iran.

  20. PATTERNS OF HABITAT FRAGMENTATION IN THE BOTUCATU – SP CUESTA

    Directory of Open Access Journals (Sweden)

    Luiz Alberto Blanco Jorge

    2009-09-01

    Full Text Available The overall goal of the present work was to continue studying habitat fragmentation in the Botucatu Cuesta, SP, Brazil, in a 18422-ha study. Landsat-5 TM images were used and a technique was developed to subtract data other than vegetation data from the scene. Thus natural vegetation thematic maps for different dates (1986 and 1993 were generated. The analysis of 1986 and 1993 spatial   data  revealed   that   habitat  fragmentation  in  the  study  area  was  unstable. The  process presented scale distinction, i.e., 1 in  the  largest  patches  subset  the  phenomenon was non-fractal and patch size decreased following a linear tendency; 2 in the intermediary size subset of patches, the phenomenon was non-fractal and patches size decreased in an increasing geometric progression; 3 in the smallest patches subset, the phenomenon was fractal, divided patches tending to follow a geometric progression.

  1. Multi-View Algorithm for Face, Eyes and Eye State Detection in Human Image- Study Paper

    Directory of Open Access Journals (Sweden)

    Latesh Kumari

    2014-07-01

    Full Text Available For fatigue detection such as in the application of driver‟s fatigue monitoring system, the eye state analysis is one of the important and deciding steps to determine the fatigue of driver‟s eyes. In this study, algorithms for face detection, eye detection and eye state analysis have been studied and presented as well as an efficient algorithm for detection of face, eyes have been proposed. Firstly the efficient algorithm for face detection method has been presented which find the face area in the human images. Then, novel algorithms for detection of eye region and eye state are introduced. In this paper we propose a multi-view based eye state detection to determine the state of the eye. With the help of skin color model, the algorithm detects the face regions in an YCbCr color model. By applying the skin segmentation which normally separates the skin and non-skin pixels of the images, it detects the face regions of the image under various lighting and noise conditions. Then from these face regions, the eye regions are extracted within those extracted face regions. Our proposed algorithms are fast and robust as there is not pattern match.

  2. Eye-Tracking Study of Complexity in Gas Law Problems

    Science.gov (United States)

    Tang, Hui; Pienta, Norbert

    2012-01-01

    This study, part of a series investigating students' use of online tools to assess problem solving, uses eye-tracking hardware and software to explore the effect of problem difficulty and cognitive processes when students solve gas law word problems. Eye movements are indices of cognition; eye-tracking data typically include the location,…

  3. Quantitative study of spontaneous eye blinks and eye tics in Gilles de la Tourette's syndrome

    NARCIS (Netherlands)

    J.H.M. Tulen (Joke); M. Azzolini; J.A. de Vries; W.H. Groeneveld; J. Passchier (Jan); B.J.M. van de Wetering (Ben)

    1999-01-01

    textabstractSpontaneous eye blink rate and frequency of eye tics were studied in nine Tourette patients during periods of rest, conversation, and video watching. In comparison with controls, the Tourette patients showed a significantly higher blink rate during rest and

  4. Peripapillary intrachoroidal cavitations. The Beijing eye study.

    Directory of Open Access Journals (Sweden)

    Qi Sheng You

    Full Text Available PURPOSE: To assess prevalence, size and location of peripapillary intrachoroidal cavitations (PICCs and their associations in a population-based sample. . METHODS: The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6 ± 9.8 years (range:50-93 years. A detailed ophthalmic examination included enhanced depth imaging of the choroid by spectral-domain optical coherence tomography and fundus photography. PICCs were defined as triangular thickening of the choroid with the base at the optic disc border and a distance between Bruch's membrane and sclera of ≥ 200 μm. Parapapillary large choroidal vessels were excluded. RESULTS: Out of 94 subjects with high myopia (refractive error 26.5mm in right eyes, OCT images were available for 89 (94.7% participants. A PICC was detected in 15 out of these 89 highly myopic subjects (prevalence:16.9 ± 4.0% and in none of hyperopic, emmetropic or medium myopic subgroups each consisting of 100 randomly selected subjects. Mean PICC width was 4.2 ± 2.3 hours (30° of disc circumference and mean length was 1363 ± 384 μm. PICCs were located most frequently (40% at the inferior disc border. On fundus photos, a typical yellow-orange lesion was found in 8 (53% eyes with PICCs. In binary regression analysis, presence of PICCs was significantly associated with optic disc tilting (P=0.04 and presence of posterior staphylomata (P=0.046. CONCLUSIONS: Prevalence of PICCs in the adult Chinese population was 16.9 ± 4.0% in the highly myopic group, with no PICCs detected in non-highly myopic eyes. PICCs were located most frequently at the inferior optic disc border. Only half of the PICCs detected on OCT images showed a yellow-orange lesion on fundus photos. Presence of PICC was significantly associated only with an increased optic disc tilting and presence of posterior staphylomata, while it was not associated with axial length, refractive error or other ocular or systemic parameters.

  5. Submacular hemorrhage: A study amongst Indian eyes

    Directory of Open Access Journals (Sweden)

    Ekta Rishi

    2012-01-01

    Full Text Available Aim: To evaluate the management outcomes amongst various treatment modalities for submacular hemorrhage (SMH in Indian subjects. Settings and Design: Retrospective, single-center study. Materials and Methods: Patients presenting with SMH between 1999 and 2006 were included. Treatment modalities included: vitrectomy with subretinal recombinant tissue plasminogen activator (r-tPA assisted SMH evacuation (group 1, n = 14; pneumatic displacement with intravitreal r-tPA and gas (group 2, n = 25; and pneumatic displacement with intraocular gas (group 3, n = 7. Favorable anatomical outcome was defined as complete displacement of SMH from fovea and favorable functional outcome was defined as a gain of >2 Snellen lines from the baseline. Kruskal-Wallis, analysis of variance (ANOVA, and Chi-square tests were used to compare the three groups, while Mann-Whitney and independent t-test were used to evaluate the influence of duration and size of SMH on outcomes. Results: There was no difference amongst groups in terms of favorable anatomical (P = 0.121 or functional outcomes (P = 0.611. Eyes with median duration of SMH less than 7.5 days had a significantly higher probability of achieving favorable anatomical outcome compared to eyes with SMH >14.5 days (P = 0.042. However, duration of SMH did not influence functional outcome (P = 0.595. Similarly, size of SMH did not affect anatomical (P = 0.578 or functional (P = 0.381 outcome. Median follow-up was 31.5, 6.5, and 2.5 months in the three groups, respectively. Conclusions: Co- existing posterior segment conditions and duration of SMH may influence the choice of treatment modality and treatment outcomes. Pneumatic displacement with r-tPA and r-tPA assisted vitrectomy appear to be favorable options for the management of SMH.

  6. Ocorrência de leucose enzoótica bovina na microrregião da Serra de Botucatu Occurrence of bovine leukosis virus in the microregion of the Serra de Botucatu, SP, Brazil

    Directory of Open Access Journals (Sweden)

    J. Megid

    2003-10-01

    Full Text Available The aim of this study was characterize the positivity of the bovine leukosis virus in the Microregion of the Serra de Botucatu. Sera from 1193 bovine from 65 properties of the Microregion of the Serra de Botucatu were evaluated throught ELISA test. All the evaluated animals were adult and 16 of them only were male; 85.5% were crossbred, 6.45% Nellore and 8% dutch. Of the analyzed samples, 618 sera had resulted positive to the test. In only one flock it was not found seroreagents animals, the regional positivity was 52% (the seropositivity in the properties varied of 10% to 67%, the higher the percentage of positivity was in the animals of the dutch race (94.7%, followed for the crossbred (43.7%. The high percentage of positivity of the disease in our region is distinguished.

  7. Reading Mathematics Representations: An Eye-Tracking Study

    Science.gov (United States)

    Andrá, Chiara; Lindström, Paulina; Arzarello, Ferdinando; Holmqvist, Kenneth; Robutti, Ornella; Sabena, Cristina

    2015-01-01

    We use eye tracking as a method to examine how different mathematical representations of the same mathematical object are attended to by students. The results of this study show that there is a meaningful difference in the eye movements between formulas and graphs. This difference can be understood in terms of the cultural and social shaping of…

  8. Retrospective study of computed tomography of nasal cavity in small animal at FMVZ - UNESP, Botucatu, and correlation of changes with cytological and/or histopathological exams; Estudo retrospectivo de tomografia computadorizada da cavidade nasal em pequenos animais na FMVZ - UNESP, Botucatu, e correlacao das alteracoes com os exames citologico e/ou histopatologico

    Energy Technology Data Exchange (ETDEWEB)

    Belotta, Alexandra Frey; Inamassu, Leticia Rocha; Mamprim, Maria Jaqueline; Machado, Vania Maria de Vasconcelos; Vulcano, Luiz Carlos, E-mail: a_fbelotta@yahoo.com.br [Universidade Estadual Paulista Julio de Mesquita Filho (FMVZ/UNESP), Botucatu, SP (Brazil). Faculdade de Medicina Veterinaria e Zootecnia. Dept. de Reproducao Animal e Radiologia Veterinaria; Zardo, Karen Maciel

    2012-07-01

    It was conducted a retrospective study of computed tomography (CT) scans of nasal cavity in small animal at this institution during the period of April 2007 through June 2012. In total, 47 CT scans were performed during the period and, of these, only 25 underwent additional exams (cytological and/or histopathological). 20 exams suggested a diagnosis, 4 were inconclusive and one had no change. A correlation was made between tomographic findings and cytological/histopathological diagnosis providing an accurate assessment of neoplastic versus non-neoplastic disease. (author)

  9. Padrões da fragmentação do habitat na Cuesta de Botucatu (SP

    Directory of Open Access Journals (Sweden)

    Marcelo Moreira Paustein

    2000-01-01

    Full Text Available The overall goal of the present work was to continue studying habitat fragmentation in the Botucatu Cuesta, SP, Brazil, in a 18422-ha study. Landsat-5 TM images were used and a technique was developed to subtract data other than vegetation data from the scene. Thus natural vegetation thematic maps for different dates (1986 and 1993 were generated. The analysis of 1986 and 1993 spatial data revealed that habitat fragmentation in the study area was unstable. The process presented scale distinction, i.e., 1 in the largest patches subset the phenomenon was non-fractal and patch size decreased following a linear tendency; 2 in the intermediary size subset of patches, the phenomenon was non-fractal and patches size decreased in an increasing geometric progression; 3 in the smallest patches subset, the phenomenon was fractal, divided patches tending to follow a geometric progression.

  10. A mortalidade neonatal em 1998, no município de Botucatu - SP La mortalidad neonatal en 1998, en el município de Botucatu-SP The neonatal mortality in 1998 at the municipality of Botucatu-SP

    Directory of Open Access Journals (Sweden)

    Kátia Poles

    2000-07-01

    present study, whose aim was to analyze the neonatal mortality during the year of 1998 at the municipality Botucatu-SP. The coefficient of neonatal mortality was of 8,3/1000 born alive and the coefficient of precocious neonatal mortality was of 7,3/1000 born alive, confirming the importance of decease in the first week of life. Results showed that approximately 3/4 of the deceases can be reduced through precocious diagnosis and treatment as well as adequate care to birth or partially reduced through appropriate pregnancy control measures, evidencing that in order to decrease the rates of neonatal death, investments must be made to improve the quality of the care to pregnant women, parturients and the new born.

  11. Eye-tracking study of inanimate objects

    Directory of Open Access Journals (Sweden)

    Ković Vanja

    2009-01-01

    Full Text Available Unlike the animate objects, where participants were consistent in their looking patterns, for inanimates it was difficult to identify both consistent areas of fixations and a consistent order of fixations. Furthermore, in comparison to animate objects, in animates received significantly shorter total looking time, shorter longest looks and a smaller number of overall fixations. However, as with animates, looking patterns did not systematically differ between the naming and non-naming conditions. These results suggested that animacy, but not labelling, impacts on looking behavior in this paradigm. In the light of feature-based accounts of semantic memory organization, one could interpret these findings as suggesting that processing of the animate objects is based on the saliency/diagnosticity of their visual features (which is then reflected through participants eye-movements towards those features, whereas processing of the inanimate objects is based more on functional features (which cannot be easily captured by looking behavior in such a paradigm.

  12. A 1-year Study of Eye Trauma at Farabi Hospital

    Directory of Open Access Journals (Sweden)

    J. Faraji Oskooie

    1998-04-01

    Full Text Available The author conducted 1-year study investigating the causation and management of eye trauma at Farabi Eye' center. All patients sustaining eye injuries who were evaluated by ophthalmology service over one year interval were included."n. A formal questionnaire was completed with details of the injuiy being obtained. An ophthalmologic examination was performed on each patient, and examination findings and diagnostic tests obtained, diagnosis and treatment were recorded and analyzed."nNine hundreds and sixty-one injuries (65% occured in males and 503 (35% in females. The average age was 30 years. This study included 1464 eye injuries."nFour handreds and eighty-five (nearly 30% of patients were in pediatric age group. Seventy percent of all patients were admitted within 24 hours of their injury. Fourty percent of all injuries occurred in the street, 30% at home, 15% at the work place , the rest either in school or sport field."nAmong those older than 65 years of age, 70% of injuries were the result of fall. Seventy percent of all eye injuries were caused by blunt trauma. Diagnosis and management were recorded."nConclusions : Tehran and other metropolitans population is more likely to sustain eye trauma as the result of an assault and is less likely to be involved in a work- or sports-related one."nGiven poor compliance without patient management and follow-up, aggressive primary management may be indicated to optimize visual outcome

  13. Stable isotopes applied in life sciences in UNESP - Botucatu campus, SP, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Vladimir E.; Denadai, Juliana C.; Sartori, Maria M.P.; Ducatti, Carlos, E-mail: vladimir@ibb.unesp.br, E-mail: denadai@ibb.unesp.br, E-mail: mmpsartori@ibb.unesp.br, E-mail: ducatti@ibb.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (IBB/UNESP), Botucatu, SP (Brazil). Instituto de Biociencias de Botucatu

    2013-07-01

    Universities and research centers that use stable isotopes follow a worldwide trend in owning laboratories isotope ratio that serves multiple users, as well as minimize maintenance costs, operation and staff training. For this purpose it was created in 1998, the Center Stable Isotopes 'Centro de Isotopos Estaveis' - CIE, which is an auxiliary unit linked to the Institute of Biosciences (IB) of the Sao Paulo State University - UNESP Botucatu Campus, Brazil. The best way to CIE grow and achieve excellence are already disclose the methodologies employed and practice areas consolidated to find new partnerships with different applications, and also seek new methods of analysis that can expand areas. The aim of this study is to disseminate methodologies for analysis of isotope ratio and areas of the CIE. The CIE analyzes the isotopic ratios {sup 13}C/{sup 12}C, {sup 15}N/{sup 14}N, {sup 2}H/{sup 1}H and {sup 18}O/{sup 16}O (CHON), and for the carbon samples can be solid, liquid and gas (in the form of CO{sub 2}) for the other elements is only possible to analyze in solid or liquid form. All samples are always analyzed separately by the destructive method. The CIE addition to performing scientific partnerships with all university, complementary and auxiliaries units of UNESP Botucatu campus also have partnerships in other academic units on campus of UNESP Jaboticabal and Dracena and Sao Paulo University in Piracicaba campus and is open to new partnerships in other research units. (author)

  14. Incidence of the autoimmune dermatosis in dogs and cats and retrospective study of 40 cases of discoid lupus erythematosus attended at the Dermatology Service of the College of Veterinary Medicine and Animal Science of UNESP – Botucatu / Incidência das dermatopatias auto-imunes em cães e gatos e estudo retrospectivo de 40 casos de lupus eritematoso discóide atendidos no serviço de dermatologia da Faculdade de Medicina Veterinária e Zootecnia da UNESP – Botucatu

    Directory of Open Access Journals (Sweden)

    Jéssica Correa Rodrigues

    2010-09-01

    Full Text Available The objectives of this study were to do a survey of the autoimmune skin diseases and update the records regarding the occurrence of discoid lupus erythematosus in canine and feline populations attended at the Dermatology Service of the College of Veterinary Medicine and Animal Science of UNESP - Botucatu, including species, gender, breed, age, location and characteristic of the lesions. Results have shown that the order of occurrence, regarding the number of cases of autoimmune skin diseases in the animals attended by the Dermatology Service in the period from 1988 to 2007 was: discoid lupus erythematosus, pemphigus folliaceus, uveo-dermatologic syndrome, pemphigus vulgaris, systemic lupus erythematosus, necrolytic migratory erythema, multiforme erythema and plasmacytic pododermatitis. All the animals with discoid lupus erythematosus were dogs and most of them were mongrel females. More frequently breeds affected by discoid lupus erythematosus were german shepherd and akita and the mean age was 56 months. Most lesions were located in nasal planum, narines and periocular area and were characterized by crusting, depigmentation and erythema.Os objetivos do presente trabalho teve como objetivo fazer um levantamento da casuística de doenças dermatológicas auto-imunes e atualizar os dados referentes à ocorrência de lupus eritematoso discóide na população canina e felina atendida pelo Serviço de Dermatologia Veterinária da FMVZ-UNESP, campus de Botucatu, incluindo a espécie, sexo, raça, idade, localização e caracterização das lesões. Com a análise dos resultados, concluiu-se que a ordem de ocorrência de acordo com o número de casos de doenças dermatológicas auto-imunes nos animais atendidos pelo setor de dermatologia no período de 1988 a 2007 é: lupus eritematoso discóide, pênfigo foliáceo, síndrome úveo-dermatológica, pênfigo vulgar, lupus eritematoso sistêmico, eritema necrolítico migratório, eritema multiforme e

  15. Hourly model to estimate solar global radiation for all months of the year for Botucatu, Sao Paulo State; Modelos horarios para estimativa da radiacao solar global para todos os meses do ano para Botucatu-SP

    Energy Technology Data Exchange (ETDEWEB)

    Laperuta Filho, Jayme; Lunardi, Dalva M. Cury [UNESP, Botucatu, SP (Brazil). Faculdade de Ciencias Agronomicas

    1997-12-31

    The objective of this work was establish and daily models for estimate of solar global radiation for the months of the year, in Botucatu-SP 22 deg C 52`S,48 deg C 26`W Grw). The obtention of these models showed be viable high degree of reliability considering that they are specific for hours and months that originated them. The coefficients a and b presented monthly and hourly variations, taking into account that b showed higher relative variability than a. In all months studied, the linear adjustment was not appropriate before 7 a.m and after 5 p.m. (author) 7 refs., 5 tabs.

  16. Spatial map dose of nuclear medicine service of the Clinical Hospital of Botucatu, SP, Brazil; Mapa espacial de dose do servico de medicina nuclear do Hospital das Clinicas de Botucatu

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Caio V.; Mendonca, Caroline; Silva, Eduardo T.; Moriguchi, Sonia M.; Koga, Katia H., E-mail: caiov_oliveira@yahoo.com.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Faculdade de Medicina

    2013-12-15

    This study was conducted to describe levels of occupational and environmental exposure of the Nuclear Medicine Service of the Clinical Hospital of Botucatu. To this end, measurements were made of the radiometric levels of points strategically defined, in all the environments, for a period of six months, sampling different days and times, during operation normal routine of the sector. The results allow to estimate the expected dose for each environment, comparing them to the dose limitation established by the National Commission of Nuclear Energy (CNEN), allowing better targeting of occupationally exposed individuals, indicating the points where the occupation should be the minimum required, enabling the reduction of risks to potential exposures. (author)

  17. Human volunteer study with PGME: Eye irritation during vapour exposure

    NARCIS (Netherlands)

    Emmen, H.H.; Muijser, H.; Arts, J.H.E.; Prinsen, M.K.

    2003-01-01

    The objective of this study was to establish the possible occurrence of eye irritation and subjective symptoms in human volunteers exposed to propylene glycol monomethyl ether (PGME) vapour at concentrations of 0, 100 and 150 ppm. Testing was conducted in 12 healthy male volunteers using a repeated

  18. Development of Text Reading in Japanese: An Eye Movement Study

    Science.gov (United States)

    Jincho, Nobuyuki; Feng, Gary; Mazuka, Reiko

    2014-01-01

    This study examined age-group differences in eye movements among third-grade, fifth-grade, and adult Japanese readers. In Experiment 1, Japanese children, but not adults, showed a longer fixation time on logographic kanji words than on phonologically transparent hiragana words. Further, an age-group difference was found in the first fixation…

  19. SOROPREVALÊNCIA DA PNEUMONIA PROGRESSIVA OVINA (MAEDI-VISNA NA REGIÃO DE BOTUCATU – SP PREVALENCE OF SERUM ANTIBODIES TO OVINE PROGRESSIVE PNEUMONIA (MAEDI-VISNA IN BOTUCATU REGION

    Directory of Open Access Journals (Sweden)

    José Rafael Modolo

    2009-09-01

    Full Text Available O presente estudo visou determinar a soroprevalência da pneumonia progressiva ovina, na região de Botucatu, mediante prova de imunodifusão em gel de ágar (IDGA. Foram avaliadas quatrocentas amostras de soro sanguíneo de ovinos de oito propriedades de corte, com criação em sistema semi-intensivo, de diferentes municípios da região. Nenhuma das amostras de soro foi reagente na prova de IDGA. A análise desses resultados mostra discordância com estudos realizados em outros estados brasileiros, nos quais a prevalência da doença vem aumentando progressivamente.

    PALAVRAS-CHAVES: IDGA, lentivírus, ovinos.

    The present study aimed to verify the prevalence of the ovine progressive pneumonia in Botucatu region by agar gel immunodiffusion test (AGID.  Serum samples of 400 sheep from eight specific farms for meat, with type of semi-intensive breeding of different areas. All the samples tested were negative to Maedi-Visna. The analysis of results was discordant with studies made in others Brazilians states, where the prevalence of the disease comes increasing progressively.

    KEY WORDS: AGID, lentivirus, sheep.

  20. MODEL OF THE PROCESS ON LOGISTICS WASTE MANAGEMENT OF HEALTH SERVICES IN SCHOOLS OF VETERINARY BOTUCATU - SP

    Directory of Open Access Journals (Sweden)

    BRUNA C. FIORUCI

    2012-01-01

    Full Text Available Studies related to the preservation of the environment are gaining space as it grows, changing the phenomena of nature by man's notorious actions harmful to the planet. In this research study were being presented some measures that control the release of waste into the environment as well as an appropriate model for waste treatment. The issue of Waste Management of Health Services is approached by several agencies in different areas in order to propose a solution that harmonizes the interests: the environment, health, society, law, etc. Based on concepts of logistics, this study proposed improvements in storage processes with information concerning the packaging, transportation, route with minimizing the collection of the RSS to reduce costs and disposal of waste. With concepts that include legal requirements, technical standards and adaptations to the specific companies, it was possible to delineate a pattern that serves to support the implementation of a management plan to RSS the city hall of Botucatu. In this present research school work were analyzed the cost reduction and optimization of the logistics process and indicated a model of Waste Management of Health Services in establishments in the city of Botucatu, and made the steps of the process in line with legal requirements and facilitated the implementantion of these. The analysis of the local procedure made plausible some improvements in the management of hazardous wastes and contributed positively to the city with regard to preserving the environment.

  1. Individual Differences in Spatial Orientation Performances: An Eye Tracking Study

    Directory of Open Access Journals (Sweden)

    Sacide Güzin Mazman

    2013-08-01

    Full Text Available This paper includes two studies. In study 1, the computerized version of Spatial Orientation Test (Kozhevnikov & Hegarty, 2001 was standardized for determining the norm values for Turkish undergraduate students as well as demonstrating the reliability and validity of the test. In Study 1, 101 undergraduate students from two different departments were recruited and the data were collected with computerized spatial orientation test together with a demographic information form. Descriptive statistics, independent sample t test and one way ANOVA were used in data analysis. Statistical analyses revealed out that gender and years of computer experience have significant effect on spatial orientation ability scores. Test-retest reliability coefficient was found for total accuracy score as r= .778 and r=.634 for total reaction time. As a result of discriminant validity study, the correlation between the spatial orientation and mental rotation test scores was found to be very low and not significant. In study 2, individual differences between low and high spatial orientation ability groups during performing “Spatial Orientation Test” were examined through eye movements. Five high and five low spatial orientation ability level students were asked to participate in the second study. While performing Spatial Orientation Test, their eye movements were recorded. The findings indicated that there were significant differences in eye movements between different spatial orientation ability levels in terms of fixation duration. Furthermore it was found that high and low level spatial orientation level groups solved problems with different solution patterns.

  2. Prevalência e localização espacial dos casos de tracoma detectados em escolares de Botucatu, São Paulo - Brasil Prevalence and spatial distribution of trachoma among schoolchildren in Botucatu, São Paulo - Brazil

    Directory of Open Access Journals (Sweden)

    Silvana Artioli Schellini

    2010-08-01

    / SP-Brazil and its spatial distribution. METHODS: Cross-sectional study in children aged from 7 to 14 years, who attended elementary schools in Botucatu/SP in November/2005. The sample size was estimated in 2,092 children, considering the 11.2% historic prevalence of trachoma, accepting an estimation error of 10% and confidence level of 95%. The sample was random, weighted and increased by 20%, because of the possible occurrence of losses. The total number of children examined was 2,692. The diagnosis was clinical, based on WHO guidelines. For the evaluation of spatial data, the CartaLinx program (v1.2 was used, and the school demand sectors digitized according to the planning divisions of the Department of Education. The data were statistically analyzed, and the analysis of the spatial structure of events calculated using the Geode program. RESULTS: The prevalence of trachoma in schoolchildren of Botucatu was 2.9% and there were cases of follicular trachoma. The exploratory spatial analysis failed to reject the null hypothesis of randomness (R= -0.45, p>0.05, with no significant demand sectors. The analysis for the Thiessen polygons also showed that the overall pattern was random (I= -0.07, p=0.49. However, local indicators pointed to a group of low-low type for a polygon to the north of the urban area. CONCLUSION: The prevalence of trachoma in schoolchildren in Botucatu was 2.9%. The analysis of the spatial distribution did not reveal areas of greater clustering of cases. Although the overall pattern of the disease does not reproduce the socio-economic conditions of the population, the lower prevalence of trachoma was found in areas of lower social vulnerability.

  3. Application of 3-dimensional printing technology to construct an eye model for fundus viewing study.

    Directory of Open Access Journals (Sweden)

    Ping Xie

    Full Text Available To construct a life-sized eye model using the three-dimensional (3D printing technology for fundus viewing study of the viewing system.We devised our schematic model eye based on Navarro's eye and redesigned some parameters because of the change of the corneal material and the implantation of intraocular lenses (IOLs. Optical performance of our schematic model eye was compared with Navarro's schematic eye and other two reported physical model eyes using the ZEMAX optical design software. With computer aided design (CAD software, we designed the 3D digital model of the main structure of the physical model eye, which was used for three-dimensional (3D printing. Together with the main printed structure, polymethyl methacrylate(PMMA aspherical cornea, variable iris, and IOLs were assembled to a physical eye model. Angle scale bars were glued from posterior to periphery of the retina. Then we fabricated other three physical models with different states of ammetropia. Optical parameters of these physical eye models were measured to verify the 3D printing accuracy.In on-axis calculations, our schematic model eye possessed similar size of spot diagram compared with Navarro's and Bakaraju's model eye, much smaller than Arianpour's model eye. Moreover, the spherical aberration of our schematic eye was much less than other three model eyes. While in off- axis simulation, it possessed a bit higher coma and similar astigmatism, field curvature and distortion. The MTF curves showed that all the model eyes diminished in resolution with increasing field of view, and the diminished tendency of resolution of our physical eye model was similar to the Navarro's eye. The measured parameters of our eye models with different status of ametropia were in line with the theoretical value.The schematic eye model we designed can well simulate the optical performance of the human eye, and the fabricated physical one can be used as a tool in fundus range viewing research.

  4. Desempenho agronômico de bananeiras micropropagadas em Botucatu-SP Agronomic characteristics of micropropagated bananas from Botucatu

    Directory of Open Access Journals (Sweden)

    Sarita Leonel

    2004-08-01

    Full Text Available O trabalho teve como objetivo avaliar o desempenho agronômico de cultivares de bananeira 'Prata-anã', 'Maçã' e 'Nanicão', no município de Botucatu-SP. As mudas provenientes de micropropagação foram aclimatadas em estufa durante noventa dias e, posteriormente, plantadas no campo, conforme as recomendações técnicas para a cultura. Foram avaliadas características de crescimento, como número de dias do plantio à colheita, número de folhas ativas, altura de plantas e diâmetro do pseudocaule, medidas na época de emissão da inflorescência. Também foram mensuradas características de produção, entre as quais o número de frutos, diâmetro, comprimento e peso da segunda penca, peso total das pencas e número de frutos por cacho, na época da colheita. Os resultados obtidos evidenciaram que o ciclo cultural médio variou com as cultivares, sendo de 416 dias, contados do plantio à colheita para a cv 'Nanicão', que foi a mais precoce, seguido da 'Prata-anã' (434 dias e da 'Maçã' (437 dias. As três cultivares apresentaram produtividade estimada no primeiro ciclo (planta-mãe de 30,56 t.ha-1; 19,50 t.ha-1 e 14,37 t.ha-1, respectivamente, para 'Nanicão', 'Prata-anã' e 'Maçã'. Houve correlação positiva entre algumas características de crescimento e produção.The research had as purpose to evaluate the agronomic characteristics of the bananas' cultivars 'Prata-anã' (group AAB, 'Maçã' (group AAB and 'Nanicão' (group AAA under the conditions of Botucatu city, São Paulo state, Brazil. The plants origined by tissue culture were climatizated in greenhouse during 90 days and after they were planted in the yield. Were evaluated the growth parameters as days number between the planting until the harvest , leaf number, plants height and stem diameter at the flowering time. Also, were measured production parameters as fruits number, banana bunches number, fruits diameter, banana bunches weight, height and weight of second banana

  5. When art moves the eyes: a behavioral and eye-tracking study.

    Science.gov (United States)

    Massaro, Davide; Savazzi, Federica; Di Dio, Cinzia; Freedberg, David; Gallese, Vittorio; Gilli, Gabriella; Marchetti, Antonella

    2012-01-01

    The aim of this study was to investigate, using eye-tracking technique, the influence of bottom-up and top-down processes on visual behavior while subjects, naïve to art criticism, were presented with representational paintings. Forty-two subjects viewed color and black and white paintings (Color) categorized as dynamic or static (Dynamism) (bottom-up processes). Half of the images represented natural environments and half human subjects (Content); all stimuli were displayed under aesthetic and movement judgment conditions (Task) (top-down processes). Results on gazing behavior showed that content-related top-down processes prevailed over low-level visually-driven bottom-up processes when a human subject is represented in the painting. On the contrary, bottom-up processes, mediated by low-level visual features, particularly affected gazing behavior when looking at nature-content images. We discuss our results proposing a reconsideration of the definition of content-related top-down processes in accordance with the concept of embodied simulation in art perception.

  6. When art moves the eyes: a behavioral and eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Davide Massaro

    Full Text Available The aim of this study was to investigate, using eye-tracking technique, the influence of bottom-up and top-down processes on visual behavior while subjects, naïve to art criticism, were presented with representational paintings. Forty-two subjects viewed color and black and white paintings (Color categorized as dynamic or static (Dynamism (bottom-up processes. Half of the images represented natural environments and half human subjects (Content; all stimuli were displayed under aesthetic and movement judgment conditions (Task (top-down processes. Results on gazing behavior showed that content-related top-down processes prevailed over low-level visually-driven bottom-up processes when a human subject is represented in the painting. On the contrary, bottom-up processes, mediated by low-level visual features, particularly affected gazing behavior when looking at nature-content images. We discuss our results proposing a reconsideration of the definition of content-related top-down processes in accordance with the concept of embodied simulation in art perception.

  7. Subfoveal choroidal thickness and glaucoma. The Beijing Eye Study 2011.

    Directory of Open Access Journals (Sweden)

    Ya Xing Wang

    Full Text Available To examine subfoveal choroidal thickness (SFCT in eyes with glaucoma, using enhanced depth imaging spectral domain optical coherence tomography.The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6 ± 9.8 years (range: 50-93 years. A detailed ophthalmic examination was performed including spectral-domain optical coherence tomography (SD-OCT with enhanced depth imaging for measurement of SFCT, and assessment of fundus photographs for presence of glaucoma. In addition, the group of patients with chronic angle-closure glaucoma (ACG from the Beijing Eye Study (n = 37 was merged with a group of patients with chronic ACG from the Tongren hospital (n = 52.Assessments of SFCT and glaucoma were available for 3232 (93.2% subjects. After adjusting for age, axial length, gender, anterior chamber and lens thickness, SFCT was not significantly associated with presence of glaucoma (P = 0.08; regression coefficient B:-15.7. As a corollary, in logistic regression analysis with adjustment for age, axial length and intraocular pressure, presence of glaucoma was not significantly associated with SFCT (P = 0.20. If only open-angle glaucoma was considered, multivariate analysis revealed no significant association between SFCT and presence of open-angle glaucoma (P = 0.44. As a corollary, in logistic regression analysis, open-angle glaucoma was not significantly associated with SFCT (P = 0.91. In a similar manner if only ACG was taken into account, SFCT was not significantly associated with the presence of ACG (P = 0.27 in multivariate analysis. As a corollary in binary regression analysis, presence of ACG was not significantly associated with SFCT (P = 0.27.In multivariate analysis with adjustment for age, axial length, gender, anterior chamber and lens thickness, neither OAG nor ACG was associated with an abnormal SFCT.

  8. Eye Health in New Zealand: A Study of Public Knowledge, Attitudes, and Practices Related to Eye Health and Disease

    Science.gov (United States)

    Ahn, Mark J.; Frederikson, Lesley; Borman, Barry; Bednarek, Rebecca

    2011-01-01

    Purpose: This study seeks to measure the public knowledge, attitudes, and practices related to eye health and disease in New Zealand (NZ). Design/methodology/approach: A 22-item survey of 507 adults in NZ was conducted. The survey was developed using interviews and focus groups, as well as comparisons with other benchmark international studies.…

  9. Using Eye Tracking to Assess Reading Performance in Patients with Glaucoma: A Within-Person Study

    Directory of Open Access Journals (Sweden)

    Nicholas D. Smith

    2014-01-01

    Full Text Available Reading is often cited as a demanding task for patients with glaucomatous visual field (VF loss, yet reading speed varies widely between patients and does not appear to be predicted by standard visual function measures. This within-person study aimed to investigate reading duration and eye movements when reading short passages of text in a patient’s worse eye (most VF damage when compared to their better eye (least VF damage. Reading duration and saccade rate were significantly different on average in the worse eye when compared to the better eye (P<0.001 in 14 patients with glaucoma that had median (interquartile range between-eye difference in mean deviation (MD; a standard clinical measure for VF loss of 9.8 (8.3 to 14.8 dB; differences were not related to the size of the difference in MD between eyes. Patients with a more pronounced effect of longer reading duration on their worse eye made a larger proportion of “regressions” (backward saccades and “unknown” EMs (not adhering to expected reading patterns when reading with the worse eye when compared to the better eye. A between-eye study in patients with asymmetric disease, coupled with eye tracking, provides a useful experimental design for exploring reading performance in glaucoma.

  10. Consumption of productive electric power and value of agricultural production in Botucatu region; O consumo de energia eletrica produtiva e o valor da producao agropecuaria na regiao de Botucatu

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Paulo Andre de [Universidade Estadual Paulista (UNESP), Botucatu, SP (Brazil). Faculdade de Ciencias Agronomicas. Programa de Pos-Graduacao em Agronomia], e-mail: pauloandre@fca.unesp.br; Simon, Elias Jose [Universidade Estadual Paulista (UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas. Dept. de Gestao e Tecnologia Agroindustrial], e-mail: ejsimon@fca.unesp.br

    2004-07-01

    This paper objective was to settle the electric energy consumption in the countryside and the agriculture and cattle raisin production value in the counties of the Rural Development Office (EDR) of Botucatu, in the period of 1990 to 2000, trying to establish an analysis pattern to do future studies in other regions. This pattern could be used as an analysis instrument to make decisions to implement programs that look for an increase of use of electric energy as an input to join value to the rural product. In conclusion the data adjoined as EDR region do not present enough information to the relation between the production rough value and the electric energy consumption, being necessary, therefore, its disaggregation in counties. (author)

  11. Ehrlichia canis em cães atendidos em hospital veterinário de Botucatu, Estado de São Paulo, Brasil Ehrlichia canis in dogs attended in a veterinary hospital from Botucatu, São Paulo State, Brazil

    Directory of Open Access Journals (Sweden)

    Tatiana E. H. Ueno

    2009-09-01

    Full Text Available O presente estudo investigou a etiologia da erliquiose monocítica canina em 70 cães atendidos no Hospital Veterinário da Universidade Estadual Paulista, na cidade de Botucatu, durante 2001 e 2002. Os cães foram avaliados segundo achados clínicos, epidemiológicos e laboratoriais e pela amplificação parcial e sequenciamento do gene dsb de Ehrlichia. DNA de Ehrlichia canis foi amplificado e sequenciado em 28 (40,0% cães. Observou-se maior frequência deanimais positivos com idade até 12 meses (P 0,05 e 42,2% (P > 0,05 dos cães PCR positivos, respectivamente. Vinte e cinco cães com anemia ( 0,05 frente à infecção por E. canis. Todos os 28 cães positivos na PCR apresentaram trombocitopenia (This study investigated the etiology of canine ehrlichiosis and possible clinical and epidemiological data associated with the infection in 70 dogs suspect of ehrlichiosis attended at the Veterinary Hospital of the São Paulo State University in Botucatu city during 2001 and 2002. Dogs were evaluated by clinical-epidemiological and hematological data and molecular analysis by partial amplification and DNA sequencing of the ehrlichial dsb gene. E. canis DNA was amplified and sequenced in 28 (40.0% dogs. Dogs younger than 12 months old showed significantly higher infection rates (65.0%; P 0.05, and 42.4% (P > 0.05 of the PCR-positive dogs, respectively. Twenty-five anemic ( 0.05. All 28 PCR-positive dogs showed thrombocytopenia (<175 × 10³ platelets.µL-1 and revealed statistical significance (P < 0.05. E. canis was the only Ehrlichia species found in dogs in the studied region, with higher infection rates in younger dogs, and statisticallyassociated with thrombocytopenia.

  12. Prevalence of diarrheogenic Escherichia coli and rotavirus among children from Botucatu, São Paulo State, Brazil

    Directory of Open Access Journals (Sweden)

    Rodrigues J.

    2002-01-01

    Full Text Available In a one-year prospective study carried out to define the role of rotavirus and Escherichia coli in local childhood diarrhea, we determined the prevalence of both agents in 54 diarrheic children attending a health center in Botucatu. Diarrheogenic E. coli (DEC strains were characterized by O:H serotyping, a search for virulence genetic markers, and assays of adherence to HEp-2 cells. Except for enteroaggregative E. coli (EAEC, no other DEC category was detected in the children's stools. Both EAEC and rotavirus were isolated from 22 of the 54 (41.0% diarrheic children as single agents or in combination with other enteropathogens. However, when considering the presence of a single agent, EAEC was dominant and isolated from 20.4% of the patients, whereas rotavirus was detected in 14.8%. These results indicate that rotavirus and EAEC play a significant role as agents of childhood diarrhea in the local population.

  13. Valores hematológicos de capivaras (Hydrochoerus Hydrochaeris criadas em cativeiro no município de Botucatu, SP Hematological values of captive capybara (Hydrochoerus Hydrochaeris in Botucatu county, São paulo, SP, Brazil

    Directory of Open Access Journals (Sweden)

    Maid Eliane Arouca

    2000-10-01

    Full Text Available Utilizaram-se onze capivaras (Hydrochoerus hydrochaeris, cinco machos e seis fêmeas, sadias, com dois anos de idade, criadas em regime de cativeiro na Fazenda Experimental Lageado da FMVZ - UNESP de Botucatu - SP, submetidas à anestesia dissociativa com midazolam e quetamina, para o estabelecimento de valores hematológicos. Este estudo compreendeu a determinação dos valores normais de eritrograma, leucograma, proteína plasmática total e fibrinogênio.Os valores médios encontrados para machos e fêmeas foram, respectivamente, 3,62 e 3,71x10(6/mil para eritrócitos, 15,0 e 15,4g/dl para hemoglobina, 48 e 49% para volume globular, 4630 e 5200/mil para leucócitos, 6,3 e 6,4g/dl para proteína plasmática total e 240 e 316,6mg/dl para fibrinogênio. Observou-se, desse modo, a ausência de diferenças entre os sexos.Eleven healthy capybara (Hydrochoerus hydrochaeris from the Experimental Farm Lageado - FMVZ - UNESP - Botucatu, SP - Brazil, were used in order to determine the hematological values, under Midazolan and Ketamine anesthesia. This study included the determination of normal eritrogram, leucogram, total plasmatic protein and fibrinogen values. The mean values for males and females were red cell 3.62 and 3.71x10(6/mul, hemoglobin 15.0 and 15.4g/dl, PCV 48 and 49%, white cell 4630 and 5200/mul, total plasmatic protein 6.3 and 6.4mg/dl and fibrinogen 240 and 316.6mg/dl, respectively. Diference among sex was not found.

  14. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster

    Science.gov (United States)

    Iyer, Janani; Wang, Qingyu; Le, Thanh; Pizzo, Lucilla; Grönke, Sebastian; Ambegaokar, Surendra S.; Imai, Yuzuru; Srivastava, Ashutosh; Troisí, Beatriz Llamusí; Mardon, Graeme; Artero, Ruben; Jackson, George R.; Isaacs, Adrian M.; Partridge, Linda; Lu, Bingwei; Kumar, Justin P.; Girirajan, Santhosh

    2016-01-01

    About two-thirds of the vital genes in the Drosophila genome are involved in eye development, making the fly eye an excellent genetic system to study cellular function and development, neurodevelopment/degeneration, and complex diseases such as cancer and diabetes. We developed a novel computational method, implemented as Flynotyper software (http://flynotyper.sourceforge.net), to quantitatively assess the morphological defects in the Drosophila eye resulting from genetic alterations affecting basic cellular and developmental processes. Flynotyper utilizes a series of image processing operations to automatically detect the fly eye and the individual ommatidium, and calculates a phenotypic score as a measure of the disorderliness of ommatidial arrangement in the fly eye. As a proof of principle, we tested our method by analyzing the defects due to eye-specific knockdown of Drosophila orthologs of 12 neurodevelopmental genes to accurately document differential sensitivities of these genes to dosage alteration. We also evaluated eye images from six independent studies assessing the effect of overexpression of repeats, candidates from peptide library screens, and modifiers of neurotoxicity and developmental processes on eye morphology, and show strong concordance with the original assessment. We further demonstrate the utility of this method by analyzing 16 modifiers of sine oculis obtained from two genome-wide deficiency screens of Drosophila and accurately quantifying the effect of its enhancers and suppressors during eye development. Our method will complement existing assays for eye phenotypes, and increase the accuracy of studies that use fly eyes for functional evaluation of genes and genetic interactions. PMID:26994292

  15. How do we see art: an eye-tracker study

    Directory of Open Access Journals (Sweden)

    Rodrigo eQuian Quiroga

    2011-09-01

    Full Text Available We describe the pattern of fixations of subjects looking at figurative and abstract paintings from different artists (Molina, Mondrian, Rembrandt, della Francesca and at modified versions in which different aspects of these art pieces were altered with simple digital manipulations. We show that the fixations of the subjects followed some general common principles (e.g. being attracted to saliency regions but with a large variability for the figurative paintings, according to the subject’s personal appreciation and knowledge. In particular, we found different gazing patterns depending on whether the subject saw the original or the modified version of the painting first. We conclude that the study of gazing patterns obtained by using the eye-tracker technology give a useful approach to quantify how subjects observe art.

  16. [The antiallergic eye drops "polynadyme": development, experimental and clinical studies].

    Science.gov (United States)

    Maĭchuk, Iu F; Pozdniakov, V I; Pozdniakova, V V; Iakushina, L N

    2006-01-01

    The antiallergic eye drops "Polynadyme", proposed by the Helmgolz Moscow Research Institute of Eye Diseases, have been prepared by the "Sintez" PJSC (Kurgan). The drops exert a combination of antihistaminic and vasoconstrictive effects and, for better tolerability, contain a low-toxic preserving complex. The drops are polymer-based, which ensures a long action and an artificial tear effect. Preclinical rabbit trials have shown the safety of the "Polynadyme" eye drops, their specific activity in preventing an allergic reaction, and their antiallergic effect on a model of allergic conjunctivitis. Comparative clinical trials covering 150 patients have yielded excellent and good results in 93% of cases. In acute allergic reactions, hyperemia, itch, and burning diminished just 5 minutes after administration. The "Polynadyme" eye drops are effective in treating pollinous conjunctivitis, spring (vernal) keratoconjunctivitis, allergic reactions when wearing contact lenses, the dry eye syndrome, drug-induced and toxicoallergic conjunctivitis, and other ocular allergic reactions.

  17. Comparative Study of Anterior Eye Segment Measurements with Spectral Swept-Source and Time-Domain Optical Coherence Tomography in Eyes with Corneal Dystrophies

    Directory of Open Access Journals (Sweden)

    Anna K. Nowinska

    2015-01-01

    Full Text Available Purpose. To compare anterior eye segment measurements and morphology obtained with two optical coherence tomography systems (TD OCT, SS OCT in eyes with corneal dystrophies (CDs. Methods. Fifty healthy volunteers (50 eyes and 54 patients (96 eyes diagnosed with CD (epithelial basement membrane dystrophy, EBMD = 12 eyes; Thiel-Behnke CD = 6 eyes; lattice CD TGFBI type = 15 eyes; granular CD type 1 = 7 eyes, granular CD type 2 = 2 eyes; macular CD = 23 eyes; and Fuchs endothelial CD = 31 eyes were recruited for the study. Automated and manual central corneal thickness (aCCT, mCCT, anterior chamber depth (ACD, and nasal and temporal trabecular iris angle (nTIA, tTIA were measured and compared with Bland-Altman plots. Results. Good agreement between the TD and SS OCT measurements was demonstrated for mCCT and aCCT in normal individuals and for mCCT in the CDs group. The ACD, nTIA, and tTIA measurements differed significantly in both groups. TBCD, LCD, and FECD caused increased CCT. MCD caused significant corneal thinning. FECD affected all analyzed parameters. Conclusions. Better agreement between SS OCT and TD OCT measurements was demonstrated in normal individuals compared to the CDs group. OCT provides comprehensive corneal deposits analysis and demonstrates the association of CD with CCT, ACD, and TIA measurements.

  18. Construindo conceitos sobre alimentação saudável com Escolares da rede municipal de ensino de Botucatu,SP

    OpenAIRE

    Rodrigues, Lívia Bernardes [UNESP; Camargo, Isabella Matheus [UNESP; Barim, Estela Maria [UNESP; Dias, Luiza Cristina Godim Domingues [UNESP

    2011-01-01

    This study highlights the importance of healthy eating in school with a focus on maintaining and promoting appropriate health status. Therefore, the objective was to discuss with school age children the importance of eating healthy and extend this information to parents and school staff. Participants were 76 pupils aged between 9 and 12 years, enrolled in 5th and 6th grades in a Municipal School of Basic Education (EMEF) located in a neighborhood on the outskirts of the city of Botucatu-SP. T...

  19. Associations between subjective happiness and dry eye disease: a new perspective from the Osaka study.

    Directory of Open Access Journals (Sweden)

    Motoko Kawashima

    Full Text Available Dry eye disease has become an important health problem. A lack of concordance between self-reported symptoms and the outcome of dry eye examinations has raised questions about dry eye disease.To explore the association between subjective happiness and objective and subjective symptoms of dry eye disease.The study adopted a cross-sectional design.All the employees of a company in Osaka, Japan.672 Japanese office workers using Visual Display Terminals (age range: 26-64 years.The dry eye measurement tools included the Schirmer test, conjunctivocorneal staining, the tear film break-up time, as well as the administration of a dry eye symptoms questionnaire. Happiness was measured by the Subjective Happiness Scale.Dry eye examination parameters, dry eye symptoms questionnaires, and the Subjective Happiness Scale score.Of the 672 workers, 561 (83.5% completed the questionnaires and examinations. The mean Subjective Happiness Scale score was 4.91 (SD = 1.01. This score was inversely correlated with the dry eye symptom score (r = -0.188, p < 0.001, but was not associated with objective findings which include conjunctivocorneal staining, low Schirmer test score, or low tear film break-up time. The level of subjective happiness was the lowest in the group without objective results, but reported subjective symptoms of dry eyes (p < 0.05.There is evidence of the relationship between subjective happiness and self-reported symptoms of dry eyes. Findings of this study revealed a new perspective on dry eye disease, including the potential for innovative treatments of a specific population with dry eye disease.

  20. Mobile eye-tracking methods in studies of audience learning in health promotion exhibitions

    DEFF Research Database (Denmark)

    Magnussen, Rikke; Zachariassen, Maria; Kharlamov, Nikita

    2017-01-01

    This paper presents a methodological discussion of the potential and challenges of involving mobile eye-tracking technology in studies of knowledge generation and learning in a science centre context. The methodological exploration is based on eye-tracking studies of audience interaction...

  1. Use of Cognitive and Metacognitive Strategies in Online Search: An Eye-Tracking Study

    Science.gov (United States)

    Zhou, Mingming; Ren, Jing

    2016-01-01

    This study used eye-tracking technology to track students' eye movements while searching information on the web. The research question guiding this study was "Do students with different search performance levels have different visual attention distributions while searching information online? If yes, what are the patterns for high and low…

  2. Eye movement desensitization in fibromyalgia: a pilot study.

    Science.gov (United States)

    Friedberg, Fred

    2004-11-01

    The purpose of this study was to investigate the effectiveness of eye movement desensitization (EMD) for the relief of pain, fatigue and anxiety and depression in fibromyalgia patients. Six Caucasian female patients (mean age=43.2 yr) participated in two treatment sessions. Outcome assessments included the Fibromyalgia Impact Questionnaire, Fatigue Scale, Beck Anxiety Inventory, and Beck Depression Inventory. In-session process measures included thermal biofeedback monitoring and subjective units of discomfort ratings of pain, stress, and fatigue. Four out of six subjects were considered treatment responders. Thermal biofeedback monitoring revealed an average increase in hand temperature of 5.4 degrees indicating a relaxation effect. At treatment termination, average scores decreased on the measures of anxiety (28.6%), depression (29.9%), fibromyalgia impact (12.6%), and fatigue (11.5%). At the 3-month follow-up assessment, total reductions in average scores from pre-treatment baseline reflected further improvements on measures of anxiety (45.8%), depression (31.6%), fibromyalgia impact (19.2%), and fatigue (26.7%). Because EMD produced a somewhat automatic relaxation response with minimal patient participation, it may be especially useful when standard relaxation techniques fail.

  3. Estudo da situação epidemiológica da brucelose e tuberculose bovina em propriedades fornecedoras de leite para o programa Laticínio Escola do município de Botucatu-SP

    OpenAIRE

    Maurelio, Anna Paula Vitirito [UNESP

    2014-01-01

    Brucellosis and tuberculosis are chronic infectious diseases and considered as zoonosis, which represent large economic losses to dairy cattle and public health. Our objectives were to study the epidemiological situation of these diseases in the properties that supply milk to the Municipal Program of Botucatu entitled Dairy School; determine the degree of knowledge of small farmers about these diseases through a questionnaire prepared for this purpose. At the end of the questionnaire the prod...

  4. Eye Allergies

    Science.gov (United States)

    ... Español Eye Health / Eye Health A-Z Eye Allergies Sections What Are Eye Allergies? Eye Allergy Symptoms ... allergy diagnosis Eye allergy treatment What Are Eye Allergies? Written by: David Turbert Reviewed by: Brenda Pagan- ...

  5. Dry Eye

    Science.gov (United States)

    ... Eye > Facts About Dry Eye Facts About Dry Eye This information was developed by the National Eye ... the best person to answer specific questions. Dry Eye Defined What is dry eye? Dry eye occurs ...

  6. Progression of diabetic retinopathy: the Beijing Eye Study

    Institute of Scientific and Technical Information of China (English)

    TU Ying; XU Liang; WEI Wen-bin; WANG Shuang; WANG Ya-xing; Jost B Jonas

    2011-01-01

    Background Diabetic retinopathy (DR) has emerged as a leading cause of visual impairment and blindness in the working-aged population worldwide.This study aimed to assess frequency and associated factors of progression of DR in subjects with known diabetes in a population-based setting.Methods The Beijing Eye Study is a population based study performed in Greater Beijing in 2001 and 2006.The present investigation included all subjects with known diabetes mellitus in 2001,who participated in the follow-up examination in 2006.Fundus photographs were assessed.Results The study included 170 subjects; 51 (30%) subjects showed signs of DR in 2001 and were re-examined in 2006,36 (21.2%) subjects (18 subjects with DR present at baseline,18 subjects with newly diagnosed DR in 2006)showed a progression of DR during follow-up.Progression of DR was associated with rural region (odds ratio (OR):5.43,P=0.001) and self-reported arterial hypertension (OR:3.85,P=0.023).In the non-progressive subgroup,presence of DR was associated with different levels of education (<middle school,middle school,college or higher,OR:0.30,P=0.023),treatment modes of diabetes mellitus (OR:10.24,P=0.003) and cataract surgery (OR:9.14,P=0.007).Conclusions In a population-based setting in Greater Beijing,progression of DR occurred in 35% of subjects with pre-existing DR and overall in 21% of subjects with known diabetes within a 5-year period.Progression of DR was significantly associated with rural region and self-reported arterial hypertension.In the stable subjects,presence of DR was significantly associated with poor educational level,insulin treatment of diabetes and cataract surgery.

  7. Aspectos epidemiológicos da tuberculose pulmonar nos municípios de Botucatu, Conchas, São Manuel e Avaré, Estado de São Paulo, Brasil, de 1963 a 1972 Epidemiological aspects of pulmonary tuberculosis in Botucatu, Conchas, São Manuel and Avaré (State of S. Paulo, from 1963 to 1972

    Directory of Open Access Journals (Sweden)

    Cecilia Magaldi

    1976-12-01

    ífica em adultos jovens ainda era elevada, predominando no sexo masculino, principalmente em Conchas. Sublinhou-se a necessidade de descentralizar as atividades antituberculose para atingir um controle eficiente.The diagnosis of the pulmonary tuberculosis situation in Botucatu, Conchas, São Manuel and Avaré (State of S. Paulo was based on the study of prevalence and risk of infection, in first grade school - children, during 1972, and on morbidity and specific mortality data gathered during a ten year period, 1963 to 1972. Tuberculin survey with PPD 23 RT-2TU was carried out in 2.913 school children; 718 records from the Botucatu Public Health Center and the death certificates of residents who died in these counties or in specialized hospitals were analysed. The prevalence rates of infection for the 4 counties were respectively 2.4, 6.8, 1.9 and 4.5%. The risks of infection for 7.5 year old school-children were 0.27, 0 32, 0.20 and 0.34%. The infection level characterized these counties as constituting a medium prevalence area of pulmonary tuberculosis. The prevalence rates of infection were directly related to the incidence of smear positive cases, in all these counties. Sixty two percent (62.0 of 530 patients submitted, to direct microscopy were smear positive cases. The predominance of moderately advanced and far advanced pulmonary lesions was observed in male young adults. A high default rate (39.5, a low proportion of cure (11.9% and death (3.4% were observed. Thirty two percent were under treatment. There were no statistically significant differences between default cases and county procedence of default cases and extent of pulmonary lesions. These findings were attributed to the present technical and administrative health organization. The average incidence of confirmed cases during this period was 35.4 in Conchas, 33.1 in Avaré., 23.7 in Botucatu and 18.5 in São Manuel (per 100,000. The rates of confirmed and suspected cases together were: 57.6. 48.8, 43.8 and

  8. Eye-tracking studie av vektoranalys på LTH

    DEFF Research Database (Denmark)

    Ögren, Magnus; Nyström, Marcus

    detaljerad inblick i hur studenterna tänkte medan de löste problemet. Vi använder modern eye-tracking teknik för att mäta hur LTH-studenters visuella uppmärksamhet fördelar sig mellan texter, matematiska formler och figurer när de löser problem inom vektoranalys. Genom att filma studenters ögonrörelser med...... en höghastighetskamera ger eye-tracking data information om var man tittar med väldigt hög spatial och temporal upplösning. Detta gör att man kan följa lösningsprocessen millisekund för millisekund från problempresentation till svar. Med eye-tracking kan man alltså skilja på process och produkt....... Vektoranalys är ett mycket visuellt ämne där matematiska formler ofta har en konkret grafisk tolkning. Detta gör vektoranalysen till ett speciellt lämpligt ämne att studera med eye-tracking teknologin, då försökspersonens byte av fokus mellan formler och figurer kan utvärderas. Vi kommer att presentera...

  9. A case study of blast eye injury at work place

    Directory of Open Access Journals (Sweden)

    Prabhakar Srinivasapuram Krishnacharya

    2013-12-01

    Full Text Available This case report aims at investigating whether two consecutive surgical settings would be beneficial in achieving postoperative success for the patient with blast eye injury. A 45-year-old male patient admitted on 17 th October 2011 with history of blast eye injury. Right eye examination revealed central corneal laceration with incarceration of lens matter, multiple foreign bodies also seen embedded in the eyelid margins and in the left cornea. Computed ocular tomography showed a retained intraocular foreign body (IOFB in the right eye. Simultaneous corneal laceration repair and extraction of the ruptured lens performed as primary procedure under general anesthesia. Intraoperative posterior capsule loss was noticed with vitreous presentation. Anterior vitrectomy with removal of the IOFB was done. Foreign bodies were also removed from the left cornea. Penetrating keratoplasty (PK with scleral fixated intraocular lens implantation executed 4 months later as secondary procedure. Visual acuity maintained at 6/24 in 2 years follow-up. In conclusion, two consecutive surgical settings has the advantage of calculating the intra ocular lens power.

  10. Prevalence of second-eye cataract surgery and time interval after first-eye surgery in Iran: A clinic-based study

    Directory of Open Access Journals (Sweden)

    Marzieh Katibeh

    2013-01-01

    Conclusion: The number of cataract operations in this tertiary eye care setting increased 1.5 fold over the study period. The proportion of second-eye operations also rose from 1/4 to 1/3 during the same time.

  11. A Case-Control Study on the Oxidative Balance of 50% Autologous Serum Eye Drops

    Directory of Open Access Journals (Sweden)

    Patrícia Ioschpe Gus

    2016-01-01

    Full Text Available Importance. Autologous serum (AS eye drops are recommended for severe dry eye in patients with ocular surface disease. No description of the antioxidant balance of AS eye drops has been reported in the literature. Objective. This study sought to evaluate the total reactive antioxidant potential (TRAP and concentration of reactive oxygen species (ROS in samples of 50% AS eye drops and their correlations with the demographic characteristics and lifestyle habits of patients with ocular surface disease and healthy controls. Design. This was a case-control study with a 3-month follow-up period. Participants. 16 patients with severe dry eye disease of different etiologies and 17 healthy controls matched by age, gender, and race were included. Results. TRAP and ROS were detected at all evaluated times. There were no differences in the mean ROS (p=0.429 or TRAP (p=0.475 levels between cases and controls. No statistically significant differences in the concentrations of ROS or TRAPs were found at 0, 15, or 30 days (p for ROS = 0.087 and p for TRAP = 0.93. Neither the demographic characteristics nor the lifestyle habits were correlated with the oxidative balance of the 50% AS eye drops. Conclusions and Relevance. Both fresh and frozen 50% AS eye drops present antioxidant capacities and ROS in an apparently stable balance. Moreover, patients with ocular surface disease and normal controls produce equivalent AS eye drops in terms of oxidative properties.

  12. Diarrheagenic Escherichia coli pathotypes investigation revealed atypical enteropathogenic E. coli as putative emerging diarrheal agents in children living in Botucatu, São Paulo State, Brazil.

    Science.gov (United States)

    Dias, Regiane C B; Dos Santos, Bruna C; Dos Santos, Luis F; Vieira, Melissa A; Yamatogi, Ricardo S; Mondelli, Alessandro L; Sadatsune, Terue; Sforcin, José M; Gomes, Tânia A T; Hernandes, Rodrigo T

    2016-04-01

    The aim of the present study was to investigate the prevalence of Diarrheagenic Escherichia coli (DEC) pathotypes, a leading cause of diarrhea worldwide, among diarrheal and healthy children, up to 5 years of age, living in the city of Botucatu, São Paulo, Brazil. DEC, investigated by PCR detection of virulence factor-encoding genes associated with the distinct pathotypes, was isolated from 18.0% of the patients, and 19.0% of the controls, with enteroaggregative E. coli (EAEC), the most frequent pathotype, being detected in equal proportion between patients and controls (10.0%). Among the enteropathogenic E. coli (EPEC) isolates, only one isolate was able to produce the localized adherence pattern to HeLa cells, being thus the only typical EPEC identified. All the remaining EPEC were classified as atypical (aEPEC), and detected in 8.0% and 8.5% of the patients and controls, respectively. Regarding the serotypes, 26.5% of the analyzed EPEC isolates belonged to classical EPEC-serogroups, and the only two STEC found were serotyped as O26:H11 (patient) and O119:H7 (control). Antimicrobial susceptibility tests revealed that 43.6%, 29.5% and 2.6% of the DEC isolates were resistant to ampicillin, cotrimoxazole and gentamicin, respectively. Our data indicate that EAEC remains prevalent among children living in Botucatu, and revealed atypical EPEC as emerging putative diarrheal agents in this geographical region.

  13. Characterization of the wind behavior in Botucatu-SP region (Brazil) by Weibull distributing; Caracterizacao do comportamento eolico da regiao de Botucatu-SP atraves da distribuicao de Weibull

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel Filho, Luis Roberto Almeida [Universidade Estadual Paulista (CE/UNESP), Tupa, SP (Brazil). Coordenacao de Estagio; Cremasco, Camila Pires [Faculdade de Tecnologia de Presidente Prudente, SP (Brazil); Seraphim, Odivaldo Jose [Universidade Estadual Paulista (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas; Cagnon, Jose Angelo [Universidade Estadual Paulista (FEB/UNESP), Bauru, SP (Brazil). Faculdade de Engenharia

    2008-07-01

    The wind behavior of a region can be described by frequency distribution that provide information and characteristics needed for a possible deployment of wind energy harvesting in the region. These characteristics, such as the annual average speed, the variance and shunting line standard of the registered speeds and the density of aeolian power average hourly, can be gotten by the frequency of occurrence of determined speed, that in turn must be studied through analytical expressions. The more adjusted analytical function for aeolian distributions is the function of density of Weibull, that can be determined by numerical methods and linear regressions. Once you have determined this function, all wind characteristics mentioned above may be determined accurately. The objective of this work is to characterize the aeolian behavior in the region of Botucatu-SP and to determine the energy potential for implementation of aeolian turbines. For the development of the present research, was used an Monitorial Young Wind anemometer of Campbell company installed a 10 meters of height. The experiment was developed in the Nucleus of Alternative Energies and Renewed - NEAR of the Laboratory of Agricultural Energize of the Department of Agricultural Engineering of the UNESP, Agronomy Sciences Faculty, Lageado Experimental Farm, located in the city of Botucatu - SP. The geographic localization is defined by the coordinates 22 deg 51' South latitude (S) and 48 deg 26' Longitude West (W) and average altitude of 786 meters above sea level. The analysis was carried through using registers of speed of the wind during the period of September of 2004 the September of 2005. After determined the distribution of frequencies of the hourly average speed of the wind, it was determined function of associated Weibull, thus making possible the determination of the annual average speed of the wind (2,77 m/s), of the shunting line standard of the registered speeds (0,55 m/s), of the

  14. Prevalência de enteroparasitas na população urbana do 2.° subdistrito de Botucatu, SP (Brasil Prevalence of intestinal parasites on the populations of Botucatu, SP (Brazil

    Directory of Open Access Journals (Sweden)

    Mauro R. de Oliveira

    1974-06-01

    Full Text Available Procurou-se conhecer a prevalência de enteroparasitoses na população urbana do 2.° subdistrito de Botucatu, SP (Brasil através de exames coprológicos realizados pelos métodos de FAUST, HOFFMAN e processo de tamização. A prevalência de enteroparasitoses foi relacionada com atributos da população, tais como sexo, idade, cor e com fatores ligados ao meio ambiente. O processo de amostragem empregado foi o casual simples em duplo estágio, sendo o quarteirão a unidade primária do primeiro estágio e o domicílio a unidade do segundo estágio. Os resultados mostraram que 53,76% das 895 pessoas amostradas apresentavam-se infestadas por uma ou mais espécies de parasitas intestinais. As prevalências foram as seguintes: Ancylostomidae, 17,54%; T. trichiurus, 13,63%; A. lumbricoides, 10,69%; S. stercoralis, 6,03%; E. vermicularis, 3,69%; H. nana, 1,79%; Taenia sp, 1,22%; S. mansoni, 0,22%; E. coli, 15,53%; G. lamblia, 14,07%; E. nana, 2,35%; I. bütschlii, 1,01% e E. histolytica, 0,22%.A study of the prevalence of intestinal parasitosis on the population of Botucatu's 2nd Subdistrict, S. Paulo, Brazil, is presented. Passed stool was examined by using FAUST, HOFFMAN and tamization techniques. The prevalence of intestinal parasites is related to population characteristics such as sex, age, race and some environmental features. Simple random sampling technique in double stage was applied. Among 895 examined persons, 53,76% were infected by intestinal parasites. The prevalence of the various parasites were: Ancylostomydae, 17,54%; T. trichiurus, 13,63%; A. lumbricoides, 10,39%; E. vermiculares, 3,69%; H. nana, 1,79%; Taenia sp, 1,22%; E. coli, 15,53%; G. lamblia, 14,07%; E. nana, 2,35%; I. bütschlii, 1,01% and E. histolytica, 0,22%.

  15. [Study of biopharmaceutic characteristics of cromoglycate eye drops].

    Science.gov (United States)

    Klimas, Rimantas; Inkeniene, Asta Marija; Briedis, Vitalis; Gerbutaviciene, Rima Jūrate

    2003-01-01

    One of the factors influencing the release of active substance from the drug formulation is presence of polymeric substance resulting in increase of viscosity of eye drops. Diffusion of sodium cromoglycate from polyvinyl alcohol 1.4%, 3% solutions and hypromellose 1% aqueous solution was investigated using in vitro method and diffusion coefficients were evaluated. Release of sodium cromoglycate from polyvinyl alcohol 1.4%, 3% solutions and hypromellose 1% aqueous solution was slower than the release from aqueous solution of sodium cromoglycate. The sodium cromoglycate diffusion from ophthalmic vehicle process kinetics was influenced by viscosity of these solutions and nature of the used polymers. The diffusion process of sodium cromoglycate from 1.4% PVA solution was more intensive if compared to diffusion from 1% hypromellose solution. The influence of excipients on sodium cromoglycate diffusion from eye drop formulation was evaluated when polymeric solutions have been used as vehicles.

  16. Long-range eye tracking: A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Jayaweera, S.K.; Lu, Shin-yee

    1994-08-24

    The design considerations for a long-range Purkinje effects based video tracking system using current technology is presented. Past work, current experiments, and future directions are thoroughly discussed, with an emphasis on digital signal processing techniques and obstacles. It has been determined that while a robust, efficient, long-range, and non-invasive eye tracking system will be difficult to develop, such as a project is indeed feasible.

  17. Face, eye, and body selective responses in fusiform gyrus and adjacent cortex: an intracranial EEG study.

    Directory of Open Access Journals (Sweden)

    Andrew D Engell

    2014-08-01

    Full Text Available Functional MRI (fMRI studies have investigated the degree to which processing of whole faces, face-parts, and bodies are differentially localized within the fusiform gyrus and adjacent ventral occipitotemporal cortex. While some studies have emphasized the spatial differentiation of processing into discrete areas, others have emphasized the overlap of processing and the importance of distributed patterns of activity. Intracranial EEG (iEEG recorded from subdural electrodes provides excellent temporal and spatial resolution of local neural activity, and thus provides an alternative method to fMRI for studying differences and commonalities in face and body processing. In this study we recorded iEEG from 12 patients while they viewed images of novel faces, isolated eyes, headless bodies, and flowers. ERP analysis identified 69 occipitotemporal sites at which there was a face-, eye-, or body-selective response when contrasted to flowers. However, when comparing faces, eyes, and bodies to each other at these sites, we identified only 3 face-specific, 13 eye-specific, and 1 body-specific electrodes. Thus, at the majority of sites, faces, eyes, and bodies evoked similar responses. However, we identified ten locations at which the amplitude of the responses spatially varied across adjacent electrodes, indicating that the configuration of current sources and sinks were different for faces, eyes, and bodies. Our results also demonstrate that eye-sensitive regions are more abundant and more purely selective than face- or body-sensitive regions, particularly in lateral occipitotemporal cortex.

  18. Face, eye, and body selective responses in fusiform gyrus and adjacent cortex: an intracranial EEG study.

    Science.gov (United States)

    Engell, Andrew D; McCarthy, Gregory

    2014-01-01

    Functional MRI (fMRI) studies have investigated the degree to which processing of whole faces, face-parts, and bodies are differentially localized within the fusiform gyrus and adjacent ventral occipitotemporal cortex. While some studies have emphasized the spatial differentiation of processing into discrete areas, others have emphasized the overlap of processing and the importance of distributed patterns of activity. Intracranial EEG (iEEG) recorded from subdural electrodes provides excellent temporal and spatial resolution of local neural activity, and thus provides an alternative method to fMRI for studying differences and commonalities in face and body processing. In this study we recorded iEEG from 12 patients while they viewed images of novel faces, isolated eyes, headless bodies, and flowers. Event-related potential analysis identified 69 occipitotemporal sites at which there was a face-, eye-, or body-selective response when contrasted to flowers. However, when comparing faces, eyes, and bodies to each other at these sites, we identified only 3 face-specific, 13 eye-specific, and 1 body-specific electrodes. Thus, at the majority of sites, faces, eyes, and bodies evoked similar responses. However, we identified ten locations at which the amplitude of the responses spatially varied across adjacent electrodes, indicating that the configuration of current sources and sinks were different for faces, eyes, and bodies. Our results also demonstrate that eye-sensitive regions are more abundant and more purely selective than face- or body-sensitive regions, particularly in lateral occipitotemporal cortex.

  19. A comparative clinical study of Solcoseryl Eye-Gel and Cysteine Eye-Gel 2.4% in the treatment of foreign-body injuries of the cornea.

    Science.gov (United States)

    Studer, O

    1984-01-01

    Solcoseryl, a protein-free haemodialysate, promotes tissue regeneration and improves utilization of oxygen in the cell. In a randomized, double-blind, clinical study, Solcoseryl Eye-Gel was compared with Cysteine Eye-Gel in the treatment of foreign-body injuries of the cornea in a total of 99 eyes. In order to facilitate objective evaluation of the effects of the treatment, the area of the lesion before the start of treatment and on the following day was determined by means of slit-lamp photographs. Healing of the lesion and relative reduction of the area of the wound were observed much more frequently in the group treated with Solcoseryl Eye-Gel than in the reference group. Maculae corneae after the end of the treatment were significantly less frequent under Solcoseryl Eye-Gel than under Cysteine Eye-Gel. Teh tolerability of the test preparation was good; an itching sensation was reported in only 2 cases. Under Cysteine Eye-Gel, on the other hand, a burning sensation was reported by a number of patients and very fine deposits in the epithelium were also observed in a few cases. Thus complete closure of the epithelium over the lesion after 1 day was observed much more frequently in the group of patients treated with Solcoseryl Eye-Gel than in the reference group (63 vs. 53%).

  20. Covert tracking: a combined ERP and fixational eye movement study.

    Science.gov (United States)

    Makin, Alexis D J; Poliakoff, Ellen; Ackerley, Rochelle; El-Deredy, Wael

    2012-01-01

    Attention can be directed to particular spatial locations, or to objects that appear at anticipated points in time. While most work has focused on spatial or temporal attention in isolation, we investigated covert tracking of smoothly moving objects, which requires continuous coordination of both. We tested two propositions about the neural and cognitive basis of this operation: first that covert tracking is a right hemisphere function, and second that pre-motor components of the oculomotor system are responsible for driving covert spatial attention during tracking. We simultaneously recorded event related potentials (ERPs) and eye position while participants covertly tracked dots that moved leftward or rightward at 12 or 20°/s. ERPs were sensitive to the direction of target motion. Topographic development in the leftward motion was a mirror image of the rightward motion, suggesting that both hemispheres contribute equally to covert tracking. Small shifts in eye position were also lateralized according to the direction of target motion, implying covert activation of the oculomotor system. The data addresses two outstanding questions about the nature of visuospatial tracking. First, covert tracking is reliant upon a symmetrical frontoparietal attentional system, rather than being right lateralized. Second, this same system controls both pursuit eye movements and covert tracking.

  1. An Eye Tracking Study into the Effects of Graph Layout

    CERN Document Server

    Huang, Weidong

    2008-01-01

    Graphs are typically visualized as node-link diagrams. Although there is a fair amount of research focusing on crossing minimization to improve readability, little attention has been paid on how to handle crossings when they are an essential part of the final visualizations. This requires us to understand how people read graphs and how crossings affect reading performance. As an initial step to this end, a preliminary eye tracking experiment was conducted. The specific purpose of this experiment was to test the effects of crossing angles and geometric-path tendency on eye movements and performance. Sixteen subjects performed both path search and node locating tasks with six drawings. The results showed that small angles can slow down and trigger extra eye movements, causing delays for path search tasks, whereas crossings have little impact on node locating tasks. Geometric-path tendency indicates that a path between two nodes can become harder to follow when many branches of the path go toward the target node...

  2. Covert tracking: a combined ERP and fixational eye movement study.

    Directory of Open Access Journals (Sweden)

    Alexis D J Makin

    Full Text Available Attention can be directed to particular spatial locations, or to objects that appear at anticipated points in time. While most work has focused on spatial or temporal attention in isolation, we investigated covert tracking of smoothly moving objects, which requires continuous coordination of both. We tested two propositions about the neural and cognitive basis of this operation: first that covert tracking is a right hemisphere function, and second that pre-motor components of the oculomotor system are responsible for driving covert spatial attention during tracking. We simultaneously recorded event related potentials (ERPs and eye position while participants covertly tracked dots that moved leftward or rightward at 12 or 20°/s. ERPs were sensitive to the direction of target motion. Topographic development in the leftward motion was a mirror image of the rightward motion, suggesting that both hemispheres contribute equally to covert tracking. Small shifts in eye position were also lateralized according to the direction of target motion, implying covert activation of the oculomotor system. The data addresses two outstanding questions about the nature of visuospatial tracking. First, covert tracking is reliant upon a symmetrical frontoparietal attentional system, rather than being right lateralized. Second, this same system controls both pursuit eye movements and covert tracking.

  3. A Study on Hospital Admissions For Eye Trauma in Kashan, Iran

    Directory of Open Access Journals (Sweden)

    Movahedinejad

    2016-05-01

    Full Text Available Background Eye trauma is among the most common reasons for referral to hospital emergency departments and ophthalmologists’ offices. It also is a common cause of vision loss worldwide. However, few studies are available on the changes in the epidemiology of eye trauma in Iran in recent years. Objectives This study aimed to investigate the characteristics of hospital admissions for eye trauma in Kashan from August 2011 to February 2014. Patients and Methods A cross-sectional study was carried out on the hospital records of all patients with eye trauma who were admitted to Kashan’s Matini hospital between August 2011 and February 2014. Having an eye trauma and being hospitalized for at least one day was selected as the criteria for inclusion in the study. The data were then recorded on a checklist devised by the researcher. After entering the data into the SPSS software, descriptive statistics (i.e., percentage, frequency, mean, and standard deviation were calculated for all variables. Chi-square, Fisher’s exact test, and Mann-Whitney U test were used to analyze the data. Results In total, 200 patients with eye trauma had been hospitalized in Matini Hospital between August 2011 and February 2014. Of these patients, 86% were males, 40% were in the age range of 20-39 years, 68% lived in urban areas, and 21% of those in employment were manual and industrial workers. Approximately 38.5% of eye traumas had occurred in the work place; 72.5% of patients had penetrating injuries and 98% of cases were injured in one eye. More injuries occurred in the cornea (25.5% than elsewhere in the eye, and 75.5% of patients were treated surgically. Among all variables, only the type of trauma (P = 0.009 and cause of trauma (P = 0.004 were significantly related to the patients’ gender. Conclusions Eye trauma was prevalent among males, young people, urban residents, and manual and industrial workers. As the eyes play a vital role in daily life, communication

  4. [Skin cancer: use of preventive measures and demographic profile of a risk group in the city of Botucatu].

    Science.gov (United States)

    Popim, Regina Célia; Corrente, José Eduardo; Marino, Jaqueline Aparecida Geromel; de Souza, Carolina Arantes

    2008-01-01

    The aim of this paper was to establish the demographic profile of an at-risk group for skin cancer and to assess the preventive measures taken by the studied individuals and by the employer. The methods chosen was a quantitative study with a sample of 33 mail carriers from the Empresa Brasileira de Correios e Telégrafos in Botucatu, Brazil. Information regarding the demographic profile, how long the individual had been working for the company, hours of sun exposure, history of sunburns, family cancer history and skin cancer prevention strategies used by the company was collected by means of a questionnaire. The data were analyzed using Fisher's Exact Test at a 5% probability. The predominant age groups were 26-30 and 31-35 years corresponding to 42,42%. The predominant skin color was white (93,94%) and 81,82% of the studied individuals were working in the company for over five years. 63,63% of the interviewees use sunscreen habitually; those who do not explain this with a lack of habit (in 75% of the cases). As refers to supply of protective equipment by the company, 100% of the subjects answered positively. These findings allow characterizing the studied population as a skin cancer risk group. Prophylactic measures in form of educational actions for awareness building should be adopted and stimulated.

  5. Paleomagnetic constraints on the age of the Botucatu Formation in Rio Grande do Sul, southern Brazil

    Directory of Open Access Journals (Sweden)

    Endale Tamrat

    2006-09-01

    Full Text Available Paleomagnetic and rockmagnetic data are reported for the aeolian Botucatu Formation, in the southern Brazilian State of Rio Grande do Sul. Oriented samples were taken from a section located between the cities of Jaguari and Santiago. After thermal and alternating field demagnetization, both normal and reversed characteristic remanent magnetizations were found. These results yielded 13 reversed and 5 normal polarity sites, composing a magnetostratigraphic column displaying a sequence of reversed-normal-reversed polarity events. The paleomagnetic pole calculated for 18 sites is located at 114.7ºE, 78.5ºS (dp=8.1º; dm=1.2º, after restoring the strata to the paleohorizontal. This paleomagnetic pole indicates a Late Jurassic-Early Cretaceous age to the Botucatu Formation in the investigated area, and places the sampling sites at paleolatitudes as low as 21ºS.Dados paleomagnéticos e de magnetismo de rochas dos sedimentos eólicos da Formação Botucatu, no Estado do Rio Grande do Sul, obtidos de uma seção localizada entre as cidades de Jaguari e Santiago, permitiram definir a idade dessa formação. Direções de magnetização características com polaridades normal e reversa foram obtidas após desmagnetizações térmicas e por campos magnéticos alternados. Do total de sítios amostrados 13 apresentaram polaridade reversa e 5, polaridade normal, compondo uma coluna magnetoestratigráfica onde se identificam três horizontes de polaridade, na ordem, reverso-normal-reverso. O pólo paleomagnético baseado em 18 sítios está localizado a 114.7ºE, 78.5ºS (dp = 8.1º; dm = 1.2º, depois de restaurada a paleohorizontal dos sítios de amostragem. Este pólo paleomagnético indica idade do Jurássico Superior-Cretáceo Inferior para a Formação Botucatu na área estudada, e indica que as paleolatitudes ocupadas eram da ordem de 21ºS.

  6. Many Kids with Diabetes Missing Out on Eye Exams, Study Finds

    Science.gov (United States)

    ... news/fullstory_164258.html Many Kids With Diabetes Missing Out on Eye Exams, Study Finds Those with ... that children and teens with diabetes from poor families and those from racial/ethnic minorities were less ...

  7. Picture perception in Chinese dyslexic children: an eye-movement study

    Institute of Scientific and Technical Information of China (English)

    LI Xiu-hong; JING Jin; ZOU Xiao-bing; HUANG Xu; JIN Yu; WANG Qing-xiong; CHEN Xue-bin; YANG Bin-rang; YANG Si-yuan

    2009-01-01

    Background Currently, whether or not there is visuospatial impairments in Chinese dyslexic children is still a matter of discussion. The relatively recent application of an eye-tracking paradigm may offer an opportunity to address this issue. In China, in comparison with reading studies, there have not been nearly as many eye movement studies dealing with nonreading tasks such as picture identification and whether Chinese children with dyslexia have a picture processing deficit is not clear. The purposes of the present study were to determine whether or not there is visuospatial impairments in Chinese dyslexic children. Moreover, we attempted to discuss whether or not the abnormal eye movement pattern that dyslexic subjects show during reading of text appropriate for their age is a consequence of their linguistic difficulties.Methods An eye-link Ⅱ High-Speed Eye Tracker was used to track the series of eye-movement of 19 Chinese dyslexic children and 19 Chinese normal children. All of the subjects were presented with three pictures for this eye-tracking task and 6 relative eye-movement parameters, first fixation duration, average fixation duration, average saccade amplitude, mean saccade distance, fixation frequency and saccade frequency were recorded for analysis.Results Analyzing the relative parameter among three pictures, except for the fixation frequency and the saccade frequency, other eye-movement parameters were significantly different among the three pictures (P 0.05).Conclusions The characteristics of the pictures can significantly influence the visuospatial cognitive processing capability of the Chinese children. There is a detectable disability for the Chinese dyslexic children in the visuospatial cognitive processing: their saccade amplitude and mean saccade distance are shorter, which may be interpreted as specific for their reading disability.

  8. Study on chromatic aberration in a population of Chinese myopic eyes by means of optical design.

    Science.gov (United States)

    He, Yuanqing; Wang, Yan; Wang, Zhaoqi; Fang, Chao; Liu, Yongji; Zhang, Lin; Zheng, Shaolin; Wang, Lu; Chang, Shengjiang

    2013-05-01

    Two kinds of individual eye models, involving and without involving the angle between visual axis and optical axis, are established by means of optical design. We use them to study the properties of the transverse chromatic aberration (TCA) and longitudinal chromatic aberration (LCA) over the visible spectrum. Then the effects of the LCA and TCA on the visual quality of human eyes are evaluated. The statistical averages of TCA and LCA over the visible spectrum for Chinese myopic eyes are obtained. Results show that both TCA and LCA restrict the visual performance, and LCA is more detrimental than TCA.

  9. Anti-inflammatory and Antihistaminic Study of a Unani Eye Drop Formulation

    Directory of Open Access Journals (Sweden)

    Latif Abdul

    2010-03-01

    Full Text Available The Unani eye drop is an ophthalmic formulation prepared for its beneficial effects in the inflammatory and allergic conditions of the eyes. In the present study, the Unani eye drop formulation was prepared and investigated for its anti-inflammatory and antihistaminic activity, using in vivo and in vitro experimental models respectively. The Unani eye drop formulation exhibited significant anti-inflammatory activity in turpentine liniment-induced ocular inflammation in rabbits. The preparation also showed antihistaminic activity in isolated guinea-pig ileum. The anti-inflammatory and antihistaminic activity of eye drop may be due to presence of active ingredients in the formulation. Although there are many drugs in Unani repository which are mentioned in classical books or used in Unani clinical practice effectively in treatment of eye diseases by various Unani physicians. Inspite of the availability of vast literature, there is a dearth of commercial Unani ocular preparations. So, keeping this in mind, the eye drop formulation was prepared and its anti-inflammatory and antihistaminic activity was carried out in animal models. Thus, in view of the importance of alternative anti-inflammatory and anti- allergic drugs, it becomes imperative to bring these indigenous drugs to the front foot and evaluate their activities.

  10. Prevalence of dry eye syndrome at patients with diabetus melitus tip 2, one year retrospective study May 2011-June 2012

    Directory of Open Access Journals (Sweden)

    Nora Burda

    2012-01-01

    Conclusions: In our study the Dry Eye Syndrome showed to have a high correlation with Diabetes Mellitus Tip II (about 52.9%. Prevalence of Dry Eye was significantly higher at patients with longer duration of diabetes. Dry Eye seems to be an important contributing factor related to corneal abnormalities. Age and sex not seem to play any important role in this condition. Good glycemic control is important for prevention and control of Dry Eye Syndrome.

  11. RURAL SUSTAINABLE PRODUCTION AS A SOURCE TO BENEFIT TO SMALL FARMERS FROM BOTUCATU

    Directory of Open Access Journals (Sweden)

    SOFIA ALFREDO DE CAMPOS

    2012-01-01

    Full Text Available The sustainability issue has been discussed as an alternative to the conventional mode of production, similar to the Green Revolution. Since we live in a globalized society, where market integration is becoming increasingly dependent on meeting international standards, small farmers end up suffering the impacts that marginalize. One way to produce sustainable presented as a means of producing small farms to remain in rural areas. This research aimed to verify the benefits that the implementation of sustainability can provide family farmers of Botucatu today. The research involved documenting indirectly through the research literature and public documents. The documentation directly involved collecting data from the producers of the region through interviews and photographic record. Concluded that experiments on how to produce sustainable help small producers to become more independent of inputs, the lower the channel's marketing links, to gain loyal customers, to have with it more benefits, greater job satisfaction and remain in field. Therefore, sustainable agriculture is an experience that should be encouraged in other areas of Botucatu and other regions of Brazil as an excellent practice in agribusiness.

  12. TU-E-201-02: Eye Lens Dosimetry From CT Perfusion Studies

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, D. [Toshiba America Medical Systems (United States)

    2015-06-15

    Madan M. Rehani, Massachusetts General Hospital and Harvard Medical School, Boston Methods for Eye Lens Dosimetry and Studies On Lens Opacities with Interventionalists Radiation induced cataract is a major threat among staff working in interventional suites. Nearly 16 million interventional procedures are performed annually in USA. Recent studies by the principal investigator’s group, primarily among interventional cardiologists, on behalf of the International Atomic Energy Agency, show posterior subcapsular (PSC) changes in the eye lens in 38–53% of main operators and 21–45% of support staff. These changes have potential to lead to cataract in future years, as per information from A-Bomb survivors. The International Commission on Radiological Protection has reduced dose limit for staff by a factor of 7.5 (from 150 mSv/y to 20 mSv/y). With increasing emphasis on radiation induced cataracts and reduction in threshold dose for eye lens, there is a need to implement strategies for estimating eye lens dose. Unfortunately eye lens dosimetry is at infancy when it comes to routine application. Various approaches are being tried namely direct measurement using active or passive dosimeters kept close to eyes, retrospective estimations and lastly correlating patient dose in interventional procedures with staff eye dose. The talk will review all approaches available and ongoing active research in this area, as well as data from surveys done in Europe on status of eye dose monitoring in interventional radiology and nuclear medicine. The talk will provide update on how good is Hp(10) against Hp(3), estimations from CTDI values, Monte Carlo based simulations and current status of eye lens dosimetry in USA and Europe. The cataract risk among patients is in CT examinations of the head. Since radiation induced cataract predominantly occurs in posterior sub-capsular (PSC) region and is thus distinguishable from age or drug related cataracts and is also preventable, actions on

  13. The Experimental Study of Safety and Efficacy in Using Bovis Calculus Pharmacopuncture Solution as Eye Drop

    Directory of Open Access Journals (Sweden)

    Hyeongsik Seo

    2009-09-01

    Full Text Available Objectives : This experimental study was performed to investigate the safety and efficacy of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. To identify the use of it as eye drop, the eye irritation test of rabbits and the antibacterial test of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, and Candida albicans were performed. Methods : 1. The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration(2005. 10. 21, KFDA 2005-60. After Bovis Calculus pharmacopuncture solution was administered in the left eye of the rabbits, eye irritation of the cornea, iris and conjunctiva was observed at 1, 2, 3, 4 & 7day. 2. After administering Bovis Calculus pharmacopuncture solution on bacterial species(Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans which cause Keratitis, MIC(Minimum Inhibition Concentration and the size of inhibition zone were measured. Anti-bacterial potency was also measured using the size of inhibition zone. Results : 1. After Bovis Calculus pharmacopuncture solution was administered in the left eye of the rabbits, it was found that none of nine rabbits have abnormal signs and weight changes. 2. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, no eye irritation of the cornea, iris and conjunctiva was observed at 1, 2, 3, 4 & 7day. 3. There was no response to MIC on bacterial species (Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Aspergillus niger, Fusarium oxysporum, Candida albicans after Bovis Calculus pharmacopuncture solution was medicated. Conclusions : The present study suggests that Bovis Calculus pharmacopuncture solution is a nontoxic and non-irritant medicine, which does not cause eye irritation in

  14. Impact of Visual Impairment and Eye diseases on Mortality: the Singapore Malay Eye Study (SiMES).

    Science.gov (United States)

    Siantar, Rosalynn Grace; Cheng, Ching-Yu; Gemmy Cheung, Chui Ming; Lamoureux, Ecosse L; Ong, Peng Guan; Chow, Khuan Yew; Mitchell, Paul; Aung, Tin; Wong, Tien-Yin; Cheung, Carol Y

    2015-11-09

    We investigated the relationship of visual impairment (VI) and age-related eye diseases with mortality in a prospective, population-based cohort study of 3,280 Malay adults aged 40-80 years between 2004-2006. Participants underwent a full ophthalmic examination and standardized lens and fundus photographic grading. Visual acuity was measured using logMAR chart. VI was defined as presenting (PVA) and best-corrected (BCVA) visual acuity worse than 0.30 logMAR in the better-seeing eye. Participants were linked with mortality records until 2012. During follow-up (median 7.24 years), 398 (12.2%) persons died. In Cox proportional-hazards models adjusting for relevant factors, participants with VI (PVA) had higher all-cause mortality (hazard ratio[HR], 1.57; 95% confidence interval[CI], 1.25-1.96) and cardiovascular (CVD) mortality (HR 1.75; 95% CI, 1.24-2.49) than participants without. Diabetic retinopathy (DR) was associated with increased all-cause (HR 1.70; 95% CI, 1.25-2.36) and CVD mortality (HR 1.57; 95% CI, 1.05-2.43). Retinal vein occlusion (RVO) was associated with increased CVD mortality (HR 3.14; 95% CI, 1.26-7.73). No significant associations were observed between cataract, glaucoma and age-related macular degeneration with mortality. We conclude that persons with VI were more likely to die than persons without. DR and RVO are markers of CVD mortality.

  15. Missing X and Y: a review of participant ages in population-based eye studies.

    Science.gov (United States)

    Forward, Hannah; Hewitt, Alex W; Mackey, David A

    2012-04-01

    Ophthalmic population-based studies have been used to establish the frequency of eye disease and the associated environmental and genetic factors that cause vision impairment and blindness. Most of these studies have concentrated on the diseases of ageing: cataract, age-related macular degeneration, glaucoma and diabetic retinopathy. Other studies have identified eye diseases in children but few studies of young adult eye disease exist. We conducted a systematic review of the ophthalmic literature to identify potential population-based eye studies and then note the age of participants in the studies. We then summarized the disease specific to young adults to show there is a need for further research to identify eye disease in this important and often-neglected group in the community. Eighty-four large population-based studies have been conducted worldwide: 9 in North America, 2 in South America, 17 in Africa, 35 in Asia, 11 in Australia and the Pacific, 6 in Europe, 4 in the Middle East and 1 that covered 3 continents. No studies specifically examined young adults. Twenty-six per cent of studies included young adults as part of all ages examined but none of these examined a large number of young adults.

  16. Eye redness

    Science.gov (United States)

    Bloodshot eyes; Red eyes; Scleral injection; Conjunctival injection ... There are many causes of a red eye or eyes. Some are medical emergencies. Others are a cause for concern, but not an emergency. Many are nothing to worry about. Eye ...

  17. Radiation protection to the eye and thyroid during diagnostic cerebral angiography: a phantom study.

    LENUS (Irish Health Repository)

    Shortt, C P

    2008-08-01

    We measured radiation doses to the eye and thyroid during diagnostic cerebral angiography to assess the effectiveness of bismuth and lead shields at dose reduction. Phantom head angiographic studies were performed with bismuth (study 1) and lead shields (study 2). In study 1 (12 phantoms), thermoluminescent dosimeters (TLD) were placed over the eyes and thyroid in three groups: (i) no shields (four phantoms); (ii) anterior bismuth shields (four phantoms) and (iii) anterior and posterior bismuth shields (four phantoms). In a second study (eight phantoms), lead shields were placed over the thyroid only and TLD dose measurements obtained in two groups: (i) no shielding (four phantoms) and (ii) thyroid lead shielding (four phantoms). A standard 4-vessel cerebral angiogram was performed on each phantom. Study 1 (bismuth shields) showed higher doses to the eyes compared with thyroid (mean 13.03 vs 5.98 mSv, P < 0.001) and a higher eye dose on the X-ray tube side. Overall, the use of bismuth shielding did not significantly reduce dose to either eyes or thyroid in the measured TLD positions. In study 2, a significant thyroid dose reduction was found with the use of lead shields (47%, mean 2.46 vs 4.62 mSv, P < 0.001). Considerable doses to the eyes and thyroid highlight the need for increased awareness of patient protection. Eye shielding is impractical and interferes with diagnostic capability. Thyroid lead shielding yields significant protection to the thyroid, is not in the field of view and should be used routinely.

  18. Quantification of contributions of molecular fragments for eye irritation of organic chemicals using QSAR study.

    Science.gov (United States)

    Kar, Supratik; Roy, Kunal

    2014-05-01

    The eye irritation potential of chemicals has largely been evaluated using the Draize rabbit-eye test for a very long time. The Draize eye-irritation data on 38 compounds established by the European Center for Ecotoxicology and Toxicology of Chemicals (ECETOC) has been used in the present quantitative structure-activity relationship (QSAR) analysis in order to predict molar-adjusted eye scores (MES) and determine possible structural requisites and attributes that are primarily responsible for the eye irritation caused by the studied solutes. The developed model was rigorously validated internally as well as externally by applying principles of the Organization for Economic Cooperation and Development (OECD). The test for applicability domain was also carried out in order to check the reliability of the predictions. Important fragments contributing to higher MES values of the solutes were identified through critical analysis and interpretation of the developed model. Considering all the identified structural attributes, one can choose or design safe solutes with low eye irritant properties. The presented approach suggests a model for use in the context of virtual screening of relevant solute libraries. The developed QSAR model can be used to predict existing as well as future chemicals falling within the applicability domain of the model in order to reduce the use of animals.

  19. Design of a population-based study of visual impairment in India : The Andhra Pradesh eye disease study

    Directory of Open Access Journals (Sweden)

    Dandona Rakhi

    1997-01-01

    Full Text Available Reliable population-based epidemiologic data regarding vision and ocular morbidity, as well as those about the perceptions of people regarding visual impairment and eye care, are lacking for the most part in the developing world including India. These data are the basis on which effective eye care services can be developed. To meet this need we designed the Andhra Pradesh Eye Disease Study, a population-based epidemiology study of 10,000 people in the Indian state of Andhra Pradesh. The design of this study is described in this paper. Various options for the sample size, study areas, sampling procedure, and recruitment of subjects were considered. A sample size of 10,000 people, 5,000 each in the < or = 30 and > 30 years age groups, was determined to obtain reasonable confidence in estimating the prevalence of diseases and odds ratios for risk factors of interest. A multistage sampling strategy was chosen for the study which was assumed to give a design effect of 1.5 for the estimates. One urban area, Hyderabad, and three rural areas, West Godavari, Adilabad and Mahbubnagar districts, were selected in Andhra Pradesh. Interview instruments were developed to obtain detailed information about demographic data, diet, ocular and systemic history, risk factors for eye diseases, visual function, quality of life, barriers to eye care, and knowledge about eye diseases. A detailed examination procedure was devised to obtain a broad range of normative and abnormal data related to eyes and vision. A protocol was developed for doing automated visual fields, slitlamp and fundus photography. Computer databases were made in FoxPro for data entry and subsequent analysis with SPSS. Pilot studies were done to test the instruments, procedures, and logistics of the study in urban and rural areas. Information from the Andhra Pradesh Eye Disease Study is expected to help in planning and implementation of effective long-term preventive, curative, and

  20. One-Eyed Reading May Help Dyslexic Children—Study

    Institute of Scientific and Technical Information of China (English)

    孙颖

    2000-01-01

    本文的一个重要名词是Dyslexic(adj.),查英汉词典,得到的释义是:诵读困难的。什么是“诵读困难的”?令查阅人似懂非懂。因为,“诵读困难的”的解释可能是心理的(如注意力分散等),也可能是生理的(如近视等)。查阅英英词典,问题便迎刃而解。 Dyslexia(n.):inability to read,considered by modern educational thinkersas a condition to be treated and cured like an illness.(见Longman Dictionaryof Contemporary English,p.344)—此释义告诉读者,所谓Dyslexic,实指眼疾。 此眼疾的患者人数之众令人吃惊: Developmental dyslexia strikes nearly 20 percent of boys and five percent ofgirls,making it difficult for them to learn to read. 这么高的比例是否特指英国?文章未加说明。本文提供了一个简单而神奇的治疗方法:patching one eye(蒙住一只眼睛,而仅仅使用独眼来作阅读)。

  1. Microvasculature of the avian eye: studies on the eye of the duckling with microcorrosion casting, scanning electron microscopy, and stereology.

    Science.gov (United States)

    Hossler, F E; Olson, K R

    1984-06-01

    The microvasculature of the eye of the duckling was studied with microcorrosion casting, scanning electron microscopy, and stereology. Most blood to the eyeball first passes through the arterial ophthalmic rete mirabile, a complex of small arteries which intermixes with a similar complex of veins (venous ophthalmic rete mirabile) at the ventrotemporal angle of the eye. The present study reveals the ultrastructural anatomy and the compact, three-dimensional arrangement of vessels in this rete, which had been shown by previous investigators to function as a countercurrent heat exchanger. Vessels from this rete include the supraorbital and infraorbital arteries, which supply the eyeball anteriorly, and the ophthalmotemporal artery, which supplies the eyeball posteriorly. The internal ophthalmic and ethmoidal arteries, branches of the cerebral carotid artery, anastomose with the ophthalmotemporal artery posteriorly. Blood is distributed to the eyeball anteriorly by two ring arteries: the iridial ring artery, which circumscribes the iris and which receives blood from the long ciliary and infraorbital arteries; and the more peripheral, ciliary ring artery, which receives blood mostly from the infraorbital and ethmoidal arteries. Within the iris is a dense, freely anastomosing bed of capillaries which extends to the edge of the pupil and then loops back beneath the ciliary body. The vasculature of the ciliary body consists of radially arranged plates of anastomosing capillaries of irregular bore which mimic the contours of that organ, but permit changes in pupil diameter. The present study demonstrates the three-dimensional anatomy of the very dense capillary net of the choriocapillaris deep to the retina and the capillary mass of the pecten, and thus supports the finding of earlier investigators that nutrients diffusing from these structures nourish the avascular retina. The pecten consists of a pleated sheet of freely anastomosing capillaries which protrudes into the

  2. PADRÕES DA FRAGMENTAÇÃO DO HABITAT NA CUESTA DE BOTUCATU (SP

    Directory of Open Access Journals (Sweden)

    Luiz Alberto Blanco Jorge

    1999-11-01

    Full Text Available O objetivo global do presente trabalho foi dar prosseguimento aos estudos sobre fragmentação do habitat na Cuesta de Botucatu (SP, em uma área de 18.422 ha. A pesquisa teve os seguintes objetivos específicos : 1 mapear os fragmentos de vegetação natural que ocorrem em uma área de estudo na Cuesta de Botucatu (SP, valendo-se de imagens multiespectrais TM do satélite Landsat-5 tomadas em dois períodos (1986 e 1993; 2 avaliar a estabilidade da fragmentação do habitat, com o auxílio de um sistema de informações geográficas (SIG, comparando os mapas temáticos de ocorrência de vegetação natural de 1986 e 1993; 3 descrever os padrões da fragmentação da vegetação natural na depressão periférica da Cuesta de Botucatu (SP. A análise dos dados espaciais de 1986 e 1993 revelou que o fenômeno de fragmentação da vegetação natural é instável. O processo apresenta distinção de escala: 1 o subconjunto de fragmentos maiores não é fractal, levando à observação de que as manchas de vegetação dessa classe não se dividem, simplesmente diminuem de tamanho obedecendo a uma tendência linear; 2 o subconjunto de fragmentos de tamanhos intermediários foi detectado como não sendo fractal, levando à observação de que, no processo de fragmentação, as manchas de vegetação dessa classe não se dividem, simplesmente diminuem de tamanho, obedecendo a uma progressão geométrica crescente; 3 o subconjunto de dados relativos aos fragmentos de menor tamanho é fractal, permitindo afirmar que o processo de fragmentação relacionado a esse grupo ocorre com uma divisão dos fragmentos que obedece a uma progressão geométrica uniforme.

  3. Isolation of fungi from nature in the region of Botucatu, state of São Paulo, Brazil, an endemic area of paracoccidioidomycosis

    Directory of Open Access Journals (Sweden)

    MR Montenegro

    1996-12-01

    Full Text Available In an attempt to isolate Paracoccidioides brasiliensis from nature 887 samples of soil from Botucatu, SP, Brazil, were collected cultured in brain heart infusion agar supplemented with dextrose, in potato dextrose agar and in yeast extract starch dextrose agar, all with antibiotics, at 25º and 37ºC. Five thermo-dependent dimorphic fungi morphologically resembling P. brasiliensis were isolated; two from armadillo holes; further studies of the biology, antigenicity and genetic features of the five dimorphic fungi are necessary to clarify their taxonomy and their possible relation to P. brasiliensis. In addition, 98 dematiaceous fungi and 581 different species of Aspergillus spp. were also isolated. Our findings emphasize that armadillos and their environment are associated with thermo-dimorphic fungi and confirm the ubiquity of pathogenic dematiaceous fungi and Aspergillus spp.

  4. Processing emotion from the eyes: a divided visual field and ERP study.

    Science.gov (United States)

    Beaton, Alan A; Fouquet, Nathalie C; Maycock, Nicola C; Platt, Eleanor; Payne, Laura S; Derrett, Abigail

    2012-01-01

    The right cerebral hemisphere is preferentially involved in recognising at least some facial expressions of emotion. We investigated whether there is a laterality effect in judging emotions from the eyes. In one task a pair of emotionally expressive eyes presented in central vision had to be physically matched to a subsequently presented set of eyes in one or other visual hemifield (eyes condition). In the second task a word was presented centrally followed by a set of eyes to left or right hemifield and the participant had to decide whether the word correctly described the emotion portrayed by the laterally presented set of eyes (word condition). Participants were a group of undergraduate students and a group of older volunteers (> 50). There was no visual hemifield difference in accuracy or raw response times in either task for either group, but log-transformed times showed an overall left hemifield advantage. Contrary to the right hemisphere ageing hypothesis, older participants showed no evidence of a relative right hemisphere decline in performance on the tasks. In the younger group mean peak amplitude of the N170 component of the EEG at lateral posterior electrode sites was significantly greater over the right hemisphere (T6/PO2) than the left (T5/PO1) in both the perceptual recognition task and the emotional judgement task. It was significantly greater for the task of judging emotion than in the eyes-matching task. In future it would be useful to combine electrophysiological techniques with lateralised visual input in studying lateralisation of emotion with older as well as younger participants.

  5. Leptospira spp. and Toxoplasma gondii antibodies in vampire bats (Desmodus rotundus in Botucatu region, SP, Brazil

    Directory of Open Access Journals (Sweden)

    CB Zetun

    2009-01-01

    Full Text Available The destruction of natural ecosystems has caused several problems to humans and other animals; herein we investigate the close relationship among vampire bats, humans and domestic animals. Toxoplasma gondii and Leptospira spp. infections are two worldwide zoonoses that provoke serious damage to animals. To determine the prevalence of bats seropositive for toxoplasmosis and leptospirosis in the Botucatu region, 204 serum samples of vampire bats (Desmodus rotundus were tested for T. gondii antibodies by modified agglutination test (MAT-t and for Leptospira spp. by microscopic agglutination test (MAT-l. No animal was tested positive for T. gondii while leptospiral positivity was 7.8% for Pyrogenes, Shermani and Javanica serovars, with titers varying from 100 to 1,600. Thus, it was verified that D. rotundus does not play a relevant role in toxoplasmosis epidemiology. However, these bats can be important in the maintenance of Leptospira spp. in the environment.

  6. Microstructure parameters evaluation of Botucatu formation sandstone by X-ray microtomography

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, Jaquiel S.; Appoloni, Carlos R.; Marques, Leonardo C., E-mail: jaquielfernandes@yahoo.com.b, E-mail: appoloni@uel.b, E-mail: leocarma@yahoo.com.b [Universidade Estadual de Londrina (UEL), PR (Brazil). Dept. de Fisica. Lab. de Fisica Nuclear Aplicada; Fernandes, Celso P., E-mail: celso@lmpt.ufsc.b [Universidade Federal de Santa Catarina (UFSC), Florianopolis, SC (Brazil). Dept. de Engenharia Mecanica. Lab. de Meios Porosos e Propriedades TermoFisicas (LMPT)

    2009-07-01

    Microstructural parameters evaluation of reservoir rocks are very important to petroleum industry. This work presents total porosity and pore size distribution measurement of a silicified sandstone sample from the Botucatu formation, collected at municipal district of Faxinal, Parana, Brazil. Porosity and pores size distribution were determined using X-Ray microtomography and imaging techniques. Acquired images had 2.9 mum spatial resolution. 800 2-D images where reconstructed for the microstructure analysis. The determined average porosity was 6.1 +- 2.1 %. 95 % of the porous phase refers to pores with radius ranging from 2.9 to 167.4 mum, presenting the larger frequency (6 %) at 5.9 mum radius. The 3-D volume of the sample was reconstructed and compared with the 3-D model obtained through the autocorrelation functions from the 2-D images analysis. (author)

  7. Histological study of middle layer of rabbit fish eye (siganus javus)

    Institute of Scientific and Technical Information of China (English)

    Amir Sattari; Marziyeh Asli; Foroogh sadat Mansoori; Reza Kheirandish; Hossein Yavari

    2012-01-01

    Objectives: This study investigates the histology of the middle layer of the eye in rabbit fish Siganus javus. Methods: The eyes of twelve healthy fish were enucleated and histologic sections of 6µ were prepared. The sections were stained with Hematoxyline & Eosine (H&E) and Masson trichrom then were observed using light microscopy. Results: The middle or vascular layer consisted of the choroid and iris. The result revealed that the choroid coat was subdivided into five laminae: 1. Suprachoroid layer 2. Substina propria included choroidal gland or retemirabile, melanoid layers and connective tissue 3. Fibrouse layer 4. Choriocapillary layer 5. Separator layer. The extension of the choroid coat into the anterior compartment made the iris which mainly composed of connective tissue, blood vessels, melanocyte and a smooth muscle at the posterior part of the iris, adjacent to the pupil. The choroid coat did not continue rostrally adjacent to the cornea. Suspensory apparatus of the lens of the Siganus javus eye consisted of a dorsal suspensory ligament and a ventral retractor muscle. Conclusions: The diversity and deviation in the detail of microscopic structures in the eye of teleosts is approved through this microscopic study in middle layer of rabbit fish eye however the five differentiated parts of choroid were distinguished as in many telelost species.

  8. Histological study of the annular ligament in the rabbitfish eye (Siganus sp.).

    Science.gov (United States)

    Asli, Marziye; Mansoori, Forooghsadat; Sattari, Amir

    2012-01-01

    Rabbitfish is economically valuable teleost species which lives in shallow coastal waters. Two species of rabbit fish have been recognized in southern sea of Iran (Persian gulf) as namely Siganus sutor and Siganus javus. In the current study, in order to investigate the histology of the annular ligament of the S. javus' eye, the prepared sections of the eyes of twelve healthy specimens were studied under light microscope. The results revealed that annular ligament is a crescent shape structure which is situated between the scleral stroma anteriorly and the iris posteriorly. It contains a vascularized, amorphous and granular matrix with fibers of dense connective tissue; high glycogen content and melanin pigments.

  9. Histological study of the annular ligament in the rabbitfish eye (Siganus sp.

    Directory of Open Access Journals (Sweden)

    Marziye Asli

    2012-12-01

    Full Text Available Rabbitfish is economically valuable teleost species which lives in shallow coastalwaters. Two species of rabbit fish have been recognized in southern sea of Iran (Persiangulf as namely Siganus sutor and Siganus javus. In the current study, in order toinvestigate the histology of the annular ligament of the S. javus’ eye, the prepared sectionsof the eyes of twelve healthy specimens were studied under light microscope. The resultsrevealed that annular ligament is a crescent shape structure which is situated between thescleral stroma anteriorly and the iris posteriorly. It contains a vascularized, amorphousand granular matrix with fibers of dense connective tissue; high glycogen content andmelanin pigments.

  10. Unique Contributions of Eye-Tracking Research to the Study of Learning with Graphics

    Science.gov (United States)

    Mayer, Richard E.

    2010-01-01

    The author examines the empirical, methodological, theoretical, and practical contributions of the six studies in this special issue on eye tracking as a tool to study and enhance multimedia learning. The design of learning environments involving graphics should be consistent with a research-based theory of how people learn and evidence-based…

  11. Genetic mechanisms involved in the evolution of the cephalopod camera eye revealed by transcriptomic and developmental studies

    Directory of Open Access Journals (Sweden)

    Ogura Atsushi

    2011-06-01

    hybridization analysis of embryonic pygmy squid. Conclusion We identified 156 genes positively selected in the cephalopod lineage and 1,571 genes commonly found in the cephalopod and vertebrate camera eyes from the analysis of cephalopod camera eye specificity at the expression level. Experimental validation showed that the cephalopod camera eye-specific candidate genes include those expressed in the outer part of the optic lobes, which unique to coleoid cephalopods. The results of this study suggest that changes in gene expression and in the primary structure of proteins (through positive selection from those in the common molluscan ancestor could have contributed, at least in part, to cephalopod camera eye acquisition.

  12. Radiation protection to the eye and thyroid during diagnostic cerebral angiography: a phantom study.

    Science.gov (United States)

    Shortt, C P; Malone, L; Thornton, J; Brennan, P; Lee, M J

    2008-08-01

    We measured radiation doses to the eye and thyroid during diagnostic cerebral angiography to assess the effectiveness of bismuth and lead shields at dose reduction. Phantom head angiographic studies were performed with bismuth (study 1) and lead shields (study 2). In study 1 (12 phantoms), thermoluminescent dosimeters (TLD) were placed over the eyes and thyroid in three groups: (i) no shields (four phantoms); (ii) anterior bismuth shields (four phantoms) and (iii) anterior and posterior bismuth shields (four phantoms). In a second study (eight phantoms), lead shields were placed over the thyroid only and TLD dose measurements obtained in two groups: (i) no shielding (four phantoms) and (ii) thyroid lead shielding (four phantoms). A standard 4-vessel cerebral angiogram was performed on each phantom. Study 1 (bismuth shields) showed higher doses to the eyes compared with thyroid (mean 13.03 vs 5.98 mSv, P shielding did not significantly reduce dose to either eyes or thyroid in the measured TLD positions. In study 2, a significant thyroid dose reduction was found with the use of lead shields (47%, mean 2.46 vs 4.62 mSv, P shielding is impractical and interferes with diagnostic capability. Thyroid lead shielding yields significant protection to the thyroid, is not in the field of view and should be used routinely.

  13. POTENCIAL DE SECAGEM DO MILHO A GRANEL COM AR NATURAL EM BOTUCATU – SP DRYING POTENTIAL OF MAIZE GRAINS IN BULK WITH NATURAL AIR IN BOTUCATU, SP

    Directory of Open Access Journals (Sweden)

    Vicente A. Gonçalves

    2007-09-01

    Full Text Available

    A secagem de grãos com ar natural é um processo dependente das condições climáticas locais, constantemente oscilantes no tempo. Através do emprego de modelos matemáticos de simulação foi avaliada a possibilidade de realização da secagem do milho a granel com ar natural para as condições climáticas de Botucatu, com base nos registros horários de temperatura de bulbo seco e umidade relativa dos anos de 1971 a 1975 e de 1977 a 1981. O processo contínuo de secagem do milho com ar natural, nas condições analisadas, não permite a redução do teor de umidade final ao nível recomendado ao armazenamento seguro. A simulação da secagem intermitente, realizada nos períodos das 9 às 17 h, 9 às 18 h e 8 às 18 h, indica a possibilidade de redução do teor de umidade do milho, base úmida, a nível entre 12,1 e 17,3%, para o teor de unidade inicial de 22%, entre 12,4 e 15,5%, para o teor de umidade inicial de 20% e entre 13,1 e 14,7% para o de 18%, quando realizada a secagem no período máximo admissível.

    PALAVRAS-CHAVE: Secagem; Ar natural; Milho; Teor de umidade de equilíbrio.

    Grain drying using ambient was simulated under weather conditions in Botucatu. Hourly weather records, fry bulb temperature and relative humidity, from 1971 through 1975 and from 1977 through 1981, were used to calculate adiabatic drying potential of the ambient air. Historical weather records from 1971 were selected to simulate ambient air corn drying. Ambient air corn drying systems operating continuously are not feasible to reduce the moisture content of the grain to the moisture levels recommended for safe storage. Selective fan operation, from 9 a. m. to 5 a. m. , from 9 a. m. to 6 p. m. and from 8 a. m. to 6 p. m. , indicates the possibility to reduce corn moisture contents, wet

  14. Healthy Eyes

    Science.gov (United States)

    ... los Ojos Cómo hablarle a su oculista Healthy Eyes Having a comprehensive dilated eye exam is one ... or contact lenses. What is a comprehensive dilated eye exam? A comprehensive dilated eye exam is a ...

  15. Love is in the gaze: an eye-tracking study of love and sexual desire.

    Science.gov (United States)

    Bolmont, Mylene; Cacioppo, John T; Cacioppo, Stephanie

    2014-09-01

    Reading other people's eyes is a valuable skill during interpersonal interaction. Although a number of studies have investigated visual patterns in relation to the perceiver's interest, intentions, and goals, little is known about eye gaze when it comes to differentiating intentions to love from intentions to lust (sexual desire). To address this question, we conducted two experiments: one testing whether the visual pattern related to the perception of love differs from that related to lust and one testing whether the visual pattern related to the expression of love differs from that related to lust. Our results show that a person's eye gaze shifts as a function of his or her goal (love vs. lust) when looking at a visual stimulus. Such identification of distinct visual patterns for love and lust could have theoretical and clinical importance in couples therapy when these two phenomena are difficult to disentangle from one another on the basis of patients' self-reports.

  16. Basic study of the portable fatigue meter: effects of illumination, distance from eyes and age.

    Science.gov (United States)

    Hosokawa, T; Mikami, K; Saito, K

    1997-09-01

    Several aspects of a new, small and inexpensive fatigue assessment tool, the Portable Fatigue Meter (PFM), were studied. In the first experiment the effects of room illumination and distance between the PFM and the eyes on critical flicker fusion frequency (CFF) values were examined. The results revealed that the PFM CFF value varied significantly as a function of the distance between the indicator and the eyes, but it was not affected by room illumination. The effect of ageing on the PFM CFF value was assessed in a second experiment. The results suggested that PFM CFF values are significantly smaller in middle-aged females than in younger females.

  17. Dry Eye Disease Incidence Associated with Chronic Graft-Host Disease: Nonconcurrent Cohort Study (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Mian, Shahzad I.; De la Parra-Colín, Paola; De Melo-Franco, Rafael; Johnson, Christopher; Barrientos-Gutierrez, Tonatiuh

    2015-01-01

    Purpose: To determine if chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation (HSCT) is associated with stable or progressive dry eye disease and to determine the true incidence in patients with no prior history of dry eye disease. Methods: A nonconcurrent cohort study at a single institution with 136 patients who had no previous history of dry eye disease before HSCT. Survival analysis was used to estimate dry eye disease incidence. The incidence rate was calculated using life tables as the number of observed dry eye disease cases divided by the person-time at risk accumulated by the cohort. Transition probabilities were calculated from time of transplant to time of diagnosis, and then to last recorded visit. Results: Incidence rate was 0.8 cases of dry eye disease per person-year, and half of the population at risk developed dry eye disease during the first 10 months post transplant. Time to develop dry eye disease was 2.5 months for mild dry eye disease, 9.6 months for moderate dry eye disease, and 13.2 months for severe dry eye disease. In terms of cumulative incidence, 73% of subjects developed dry eye disease (50% mild, 16% moderate, and 7% severe) at the time of diagnosis. Conclusions: Our findings suggest that dry eye disease associated with cGVHD is an extremely frequent event and shows a wide spectrum of severity, with a mild form presenting early and a moderate to severe form presenting later after HSCT. These findings need to be studied further to elucidate if these are two different pathophysiological entities or just different expressions of the same pathology. PMID:27507907

  18. Perfil dos alunos usuários de lentes de contato do curso de Medicina da Universidade Estadual Paulista - UNESP - Botucatu Profile of medical students from the Universidade Estadual Paulista - UNESP - Botucatu, who wear contact lenses

    Directory of Open Access Journals (Sweden)

    Vanessa Gonçalves Vidotti

    2006-04-01

    Full Text Available OBJETIVO: Analisar o perfil dos usuários de lentes de contato entre os estudantes de medicina da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista - UNESP - Botucatu (SP, quanto à ametropia, à aquisição, aos cuidados e às complicações. MÉTODOS: Foi aplicado um questionário aos alunos do 1º ao 6º ano de Medicina da Faculdade de Medicina de Botucatu da Universidade Estadual Paulista - UNESP - Botucatu (SP, perfazendo um estudo analítico transversal. RESULTADOS: Foram 566 entrevistados. Destes, 155 (27,4% usavam lente de contato. Das lentes de contato usadas, 94,8% eram gelatinosas, e em 98,7% o grau era negativo. O descarte dessas lentes era mensal em 46,9% dos entrevistados e 63,9% a utilizavam, em média, 14 horas/dia. Faziam aquisição da lente de contato em óptica ou farmácia 14,1% dos estudantes. Faziam a higiene ao colocá-las e ao retirá-las dos olhos, 46,5%. As complicações referentes aos olhos vermelhos eram 51,0%; 44,5%, embaçamento; e 42,6%, sensação de corpo estranho, além de 4 estudantes relatarem "ceratite". CONCLUSÕES: A maioria dos alunos utilizava lentes hidrofílicas, descarte mensal e grau negativo. A adaptação inadequada, aquisição de lentes de contato em ópticas ou farmácias e complicações graves ocorreram, mesmo nos usuários socioculturalmente considerados diferenciados. Em vista disso, demanda a extrema necessidade de maior atenção na abordagem do tema em questão, a fim de prevenir o comprometimento visual permanente.PURPOSE: To analyze the ametropy, way of acquisition, the care and complications related to contact lens wear among medical students from Faculdade de Medicina de Botucatu da Universidade Estadual Paulista - UNESP - Botucatu (SP. METHODS: Questionnaire applied to students from the 1st to the 6th year of the Medical school of the Faculdade de Medicina de Botucatu da Universidade Estadual Paulista - UNESP - Botucatu (SP, forming an analytical cross

  19. What the Age-Related Eye Disease Studies Mean for You (AREDS2)

    Science.gov (United States)

    ... the AREDS Means for You For the Public: What the AREDS Means for You What the Age-Related Eye Disease Studies Mean for ... related nutritional supplements with a health care professional. What is the original AREDS formulation? 500 milligrams (mg) ...

  20. Infant and Adult Perceptions of Possible and Impossible Body Movements: An Eye-Tracking Study

    Science.gov (United States)

    Morita, Tomoyo; Slaughter, Virginia; Katayama, Nobuko; Kitazaki, Michiteru; Kakigi, Ryusuke; Itakura, Shoji

    2012-01-01

    This study investigated how infants perceive and interpret human body movement. We recorded the eye movements and pupil sizes of 9- and 12-month-old infants and of adults (N = 14 per group) as they observed animation clips of biomechanically possible and impossible arm movements performed by a human and by a humanoid robot. Both 12-month-old…

  1. Seeing what teachers see: Exploring the use of eye tracking in teacher expertise studies

    NARCIS (Netherlands)

    Wolff, Charlotte; Van 'T Zelfde, Hans; Jarodzka, Halszka; Boshuizen, Els

    2012-01-01

    Wolff, C., Van ’T Zelfde, H., Jarodzka, H., & Boshuizen, H. P. A. (2012, August). Seeing what teachers see: Exploring the use of eye tracking in teacher expertise studies. Poster presented at the EARLI SIG Learning and Professional Development, Antwerp, Belgium.

  2. Expertise differences in air traffic control: An eye-tracking study

    NARCIS (Netherlands)

    Van Meeuwen, Ludo; Jarodzka, Halszka; Brand-Gruwel, Saskia; Kirschner, Paul A.; De Bock, Jeano; Van Merriënboer, Jeroen

    2012-01-01

    Van Meeuwen, L. W., Jarodzka, H., Brand-Gruwel, S., Kirschner, P. A., De Bock, J. J. P. R., & Van Merriënboer, J. J. G. (2012, April). Expertise differences in air traffic control: An eye-tracking study. Paper presented at the American Educational Research Association Annual Meeting 2012, Vancouver,

  3. Eye Tracking as a Measure of Noticing: A Study of Explicit Recasts in SCMC

    Science.gov (United States)

    Smith, Bryan

    2012-01-01

    This study investigated whether eye-tracking technology could be employed as a measure of noticing of corrective feedback (in the form of explicit recasts) during NS-NNS task-based synchronous computer-mediated communication (SCMC). Pairs of university-level learners of English (n = 18) engaged in a short chat interaction task with a native…

  4. Studies of cytotoxic antibodies against eye muscle antigens in patients with thyroid-associated ophthalmopathy

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Z.-G.; Hiromatsu, Y.; Salvi, M.; Triller, H.; Bernard, N.; Wall, J.R. (Thyroid Research Unit, The Montreal General Hospital Research Institute, Montreal, Quebec (Canada)); Medeiros-Neto, G.; Iacona, A.; Lima, N. (Thyroid Clinic, Hospital das Clinicas, Sao Paulo (Brazil))

    1989-01-01

    We have studied the prevalence and significance of cytotoxic antibodies against human eye muscle cells, as detected in antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-mediated antibody-dependent cytotoxicity (CMAC) in {sup 51}Cr release assays, in patients with Graves' ophthalmopathy or Hashimoto's thyroiditis. A high prevalence of positive ADCC tests was found in all groups of patients with ophthalmopathy tested. Tests were positive in 64% of patients with Graves' ophthalmopathy from an area of severe iodine deficiency (Sao Paulo) and in 64% of such patients from an iodine replete area (Montreal). In patients with so-called ''euthyroid ophthalmopathy'', i.e. eye disease associated with thyroiditis, ADCC tests were positive in 75 and 38% of patients from the two areas, respectively, while tests were positive in 40 and 22%, respectively, of patients with Graves' hyperthyroidism without evident eye disease. In normal subjects, levels of {sup 51}Cr release was always at background levels. In a group of patients from the high-iodine area, levels of antibodies in ADCC correlated positively with the intraocular pressure (mmHg) in primary position as a parameter of eye muscle dysfunction. In patients with ophthalmopathy, positive ADCC tests were assciated with antibodies to eye muscle membrane antigens of 55,65 and 95 kD as detected by immunoblotting, although the correlation was not close for any antigen. in contrast, CMAC tests were negative in all patients with ophthalmopathy. We also tested 9 mouse and 10 human monoclonal antibodies, reactive with orbital antigens in an enzyme-linked immunosorbent assay, for cytotoxic activity, in ADCC and CMAC, against eye muscle and thyroid cells. All monoclonal antibodies were of the IgM class and negative in ADCC assays. (Abstract Truncated)

  5. Uso do solo e análise temporal da ocorrência de vegetação natural na fazenda experimental Edgardia, em Botucatu-SP Land use and temporal analysis of natural vegetation at Edgardia experimental farm - Botucatu-SP

    Directory of Open Access Journals (Sweden)

    Luiz Alberto Blanco Jorge

    2002-10-01

    Full Text Available Foram mapeados o uso do solo e as alterações das áreas de vegetação natural da Fazenda Experimental Edgardia, localizada em região de Cuesta no município de Botucatu-SP, em dois períodos (1978 e 1997, com o auxílio do sistema de informações geográficas ILWIS v.2.2 para Windows, de fotografia aérea e de imagens dos satélites Spot e Landsat-5. Cruzaram-se as informações de ocorrência da vegetação natural nas duas épocas, derivando-se um mapa temático que permitiu verificar a variação temporal das áreas dos fragmentos florestais, assim como foram observadas as associações da vegetação natural com a declividade e as unidades de solo. Analisado o intervalo de 19 anos, foram detectadas uma regeneração significativa de áreas de Floresta Estacional Semidecidual, na frente da Cuesta, em unidades de Neossolo Litólico, e uma pequena regeneração da tipologia cerradão, na depressão periférica, onde ocorrem solos de textura arenosa.The purpose of this paper was to study land use and the alterations of the natural vegetation at the Edgardia Experimental Farm, in Botucatu-SP, Brazil. Land use thematic maps for different dates (1978 and 1997 were derived from aerial photography, and Spot and Landsat-5 TM images. A G.I.S. program, ILWIS v.2.2 for Windows was used to generate spatial information. Variation in the occurrence of natural vegetation was assessed by overlaying the land use maps of both periods. This information was crossed with the slope and soil unit maps. There was a significant regeneration of the tropical moist seasonal forest fragments at the Botucatu Cuesta Front Range, and a little regeneration in the forest - savannah transition areas at the Peripheric Depression.

  6. A Pilot Study: The Efficacy of Virgin Coconut Oil as Ocular Rewetting Agent on Rabbit Eyes

    Directory of Open Access Journals (Sweden)

    Haliza Abdul Mutalib

    2015-01-01

    Full Text Available Purpose. An open-label pilot study of virgin coconut oil (VCO was conducted to determine the safety of the agent as ocular rewetting eye drops on rabbits. Methods. Efficacy of the VCO was assessed by measuring NIBUT, anterior eye assessment, corneal staining, pH, and Schirmer value before instillation and at 30 min, 60 min, and two weeks after instillation. Friedman test was used to analyse any changes in all the measurable variables over the period of time. Results. Only conjunctival redness with instillation of saline agent showed significant difference over the period of time (P0.05. There were no changes in the NIBUT, limbal redness, palpebral conjunctiva redness, corneal staining, pH, and Schirmer value over the period of time for each agent (P>0.05. Conclusion. VCO acts as safe rewetting eye drops as it has shown no significant difference in the measurable parameter compared to commercial brand eye drops and saline. These study data suggest that VCO is safe to be used as ocular rewetting agent on human being.

  7. A pilot study: the efficacy of virgin coconut oil as ocular rewetting agent on rabbit eyes.

    Science.gov (United States)

    Mutalib, Haliza Abdul; Kaur, Sharanjeet; Ghazali, Ahmad Rohi; Chinn Hooi, Ng; Safie, Nor Hasanah

    2015-01-01

    Purpose. An open-label pilot study of virgin coconut oil (VCO) was conducted to determine the safety of the agent as ocular rewetting eye drops on rabbits. Methods. Efficacy of the VCO was assessed by measuring NIBUT, anterior eye assessment, corneal staining, pH, and Schirmer value before instillation and at 30 min, 60 min, and two weeks after instillation. Friedman test was used to analyse any changes in all the measurable variables over the period of time. Results. Only conjunctival redness with instillation of saline agent showed significant difference over the period of time (P 0.05). There were no changes in the NIBUT, limbal redness, palpebral conjunctiva redness, corneal staining, pH, and Schirmer value over the period of time for each agent (P > 0.05). Conclusion. VCO acts as safe rewetting eye drops as it has shown no significant difference in the measurable parameter compared to commercial brand eye drops and saline. These study data suggest that VCO is safe to be used as ocular rewetting agent on human being.

  8. Twins eye study in Tasmania (TEST): rationale and methodology to recruit and examine twins.

    Science.gov (United States)

    Mackey, David A; Mackinnon, Jane R; Brown, Shayne A; Kearns, Lisa S; Ruddle, Jonathan B; Sanfilippo, Paul G; Sun, Cong; Hammond, Christopher J; Young, Terri L; Martin, Nicholas G; Hewitt, Alex W

    2009-10-01

    Visual impairment is a leading cause of morbidity and poor quality of life in our community. Unravelling the mechanisms underpinning important blinding diseases could allow preventative or curative steps to be implemented. Twin siblings provide a unique opportunity in biology to discover genes associated with numerous eye diseases and ocular biometry. Twins are particularly useful for quantitative trait analysis through genome-wide association and linkage studies. Although many studies involving twins rely on twin registries, we present our approach to the Twins Eye Study in Tasmania to provide insight into possible recruitment strategies, expected participation rates and potential examination strategies that can be considered by other researchers for similar studies. Five separate avenues for cohort recruitment were adopted: (1) piggy-backing existing studies where twins had been recruited, (2) utilizing the national twin registry, (3) word-of-mouth and local media publicity, (4) directly approaching schools, and finally (5) collaborating with other research groups studying twins.

  9. A review on eye movement studies in childhood and adolescent psychiatry.

    NARCIS (Netherlands)

    Lambregts-Rommelse, N.N.J.; Stigchel, S Van der; Sergeant, J.A.

    2008-01-01

    The neural substrates of eye movement measures are largely known. Therefore, measurement of eye movements in psychiatric disorders may provide insight into the underlying neuropathology of these disorders. Visually guided saccades, antisaccades, memory guided saccades, and smooth pursuit eye movemen

  10. Through Queers' Eyes: Critical Educational Ethnography in Queer Studies

    Science.gov (United States)

    Chang, Yin-Kun

    2005-01-01

    In this paper, the author provides an overview of the theoretical background of critical educational research--namely, critical pedagogy--and discusses the relationship between critical pedagogy and queer issues. In doing this, the author addresses the current strengths and weaknesses of queer studies in education. The author suggests that making…

  11. Learning from Concept Mapping and Hypertext: An Eye Tracking Study

    Science.gov (United States)

    Amadieu, Franck; Salmerón, Ladislao; Cegarra, Julien; Paubel, Pierre-Vincent; Lemarié, Julie; Chevalier, Aline

    2015-01-01

    This study examined the effects of prior domain knowledge and learning sequences on learning with concept mapping and hypertext. Participants either made a concept map in a first step and then read the hypertext's contents combined with concept mapping (high activating condition), or they read the hypertext's contents first and then made a concept…

  12. Ocular Trauma in a Rural Population of North China:The Handan Eye Study

    Institute of Scientific and Technical Information of China (English)

    ZHOU Jun; WANG Feng Hua; LU Hai; LIANG Yuan Bo; WANG Ning Li; the Handan Eye StudYGroup

    2015-01-01

    Objective To determine the prevalence of ocular trauma and the proportion of blindness and visual impairment due to trauma in a rural population in northern China. Methods The Handan Eye Study is a population-based cross-sectional study that surveyed 6830 Chinese people aged 30+years from 13 randomly selected villages in Yongnian County, city of Handan, Hebei Province, in July, 2006. All participants underwent a standardized interview and extensive examinations. A structured questionnaire was used to collect information on ocular trauma. Results Of the 5837 participants who filled out the questionnaire, 124 subjects [2.1%;95%confidence interval (CI), 1.8%-2.5%] reported a history of ocular trauma in either eye, including 19 (0.3%) persons reporting trauma in both eyes. Men were more likely to have an eye injury than women [odds ratio (OR), 3.3;2.2-4.9]. In multiple logistic regression models, ocular trauma was significantly more frequent among normotensive participants when compared with hypertensive participants (hypertensive vs. normotensive:OR, 0.6;0.4-0.9) and among participants who had a history of falls (OR, 2.4;1.2-4.8). The proportion of unilateral visual impairment and unilateral blindness due to trauma were 10.5% (13 subjects) and 21.0%(26 subjects), respectively. Conclusion Our study reports the prevalence of severe ocular trauma among adults in rural China, revealing a high proportion of blindness and visual impairment due to trauma. These findings suggest the need for educational strategies to increase eye health awareness in this rural population with focus on providing at least appropriate first aid care to reduce blindness due to trauma.

  13. Eye-tracking in amyotrophic lateral sclerosis: A longitudinal study of saccadic and cognitive tasks.

    Science.gov (United States)

    Proudfoot, Malcolm; Menke, Ricarda A L; Sharma, Rakesh; Berna, Claire M; Hicks, Stephen L; Kennard, Christopher; Talbot, Kevin; Turner, Martin R

    2015-01-01

    A relative preservation of eye movements is notable in ALS, but saccadic functions have not been studied longitudinally. ALS overlaps with FTD, typically involving executive dysfunction, and eye-tracking offers additional potential for the assessment of extramotor pathology where writing and speaking are both impaired. Eye-tracking measures (including anti-saccade, trail-making and visual search tasks) were assessed at six-monthly intervals for up to two years in a group of ALS (n = 61) and primary lateral sclerosis (n = 7) patients, compared to healthy age-matched controls (n = 39) assessed on a single occasion. Task performance was explored speculatively in relation to resting-state functional MRI (R-FMRI) network connectivity. Results showed that ALS patients were impaired on executive and visual search tasks despite normal basic saccadic function, and impairments in the PLS patients were unexpectedly often more severe. No significant progression was detected longitudinally in either group. No changes in R-FMRI network connectivity were identified in relation to patient performance. In conclusion, eye-tracking offers an objective means to assess extramotor cerebral involvement in ALS. The relative resistance of pure oculomotor function is confirmed, and higher-level executive impairments do not follow the same rate of decline as physical disability. PLS patients may have more cortical dysfunction than has been previously appreciated.

  14. Eye contact perception in the West and East: a cross-cultural study.

    Directory of Open Access Journals (Sweden)

    Shota Uono

    Full Text Available This study investigated whether eye contact perception differs in people with different cultural backgrounds. Finnish (European and Japanese (East Asian participants were asked to determine whether Finnish and Japanese neutral faces with various gaze directions were looking at them. Further, participants rated the face stimuli for emotion and other affect-related dimensions. The results indicated that Finnish viewers had a smaller bias toward judging slightly averted gazes as directed at them when judging Finnish rather than Japanese faces, while the bias of Japanese viewers did not differ between faces from their own and other cultural backgrounds. This may be explained by Westerners experiencing more eye contact in their daily life leading to larger visual experience of gaze perception generally, and to more accurate perception of eye contact with people from their own cultural background particularly. The results also revealed cultural differences in the perception of emotion from neutral faces that could also contribute to the bias in eye contact perception.

  15. Classroom misbehavior in the eyes of students: a qualitative study.

    Science.gov (United States)

    Sun, Rachel C F; Shek, Daniel T L

    2012-01-01

    Using individual interviews, this study investigated perceptions of classroom misbehaviors among secondary school students in Hong Kong (N = 18). Nineteen categories of classroom misbehaviors were identified, with talking out of turn, disrespecting teacher, and doing something in private being most frequently mentioned. Findings revealed that students tended to perceive misbehaviors as those actions inappropriate in the classroom settings and even disrupting teachers' teaching and other students' learning. Among various misbehaviors, talking out of turn and disrespecting teacher were seen as the most disruptive and unacceptable. These misbehaviors were unacceptable because they disturbed teaching and learning, and violated the values of respect, conformity, and obedience in the teacher-student relationship within the classroom. The frequency and intensity of misbehaviors would escalate if students found it fun, no punishment for such misbehaviors, or teachers were not authoritative enough in controlling the situations. Implications for further research and classroom management are discussed.

  16. Classroom Misbehavior in the Eyes of Students: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Rachel C. F. Sun

    2012-01-01

    Full Text Available Using individual interviews, this study investigated perceptions of classroom misbehaviors among secondary school students in Hong Kong (N=18. Nineteen categories of classroom misbehaviors were identified, with talking out of turn, disrespecting teacher, and doing something in private being most frequently mentioned. Findings revealed that students tended to perceive misbehaviors as those actions inappropriate in the classroom settings and even disrupting teachers' teaching and other students' learning. Among various misbehaviors, talking out of turn and disrespecting teacher were seen as the most disruptive and unacceptable. These misbehaviors were unacceptable because they disturbed teaching and learning, and violated the values of respect, conformity, and obedience in the teacher-student relationship within the classroom. The frequency and intensity of misbehaviors would escalate if students found it fun, no punishment for such misbehaviors, or teachers were not authoritative enough in controlling the situations. Implications for further research and classroom management are discussed.

  17. Estimativas de parámetros genéticos para la selección de clones de Eucalyptus en la región de Botucatu, SP. Prediction of genetic parameters for selection of clones of Eucalyptus in Botucatu, SP.

    Directory of Open Access Journals (Sweden)

    Evandro Vagner TAMBARUSSI

    2015-12-01

    Full Text Available Este trabajo trata del estudio de estimativas de parámetros genéticos cuantitativos en un ensayo clonal para la selección precoz de clones superiores de eucalipto e posterior plantío comercial. De esta forma, el objetivo de este estudio fue estimar la variabilidad genética y determinar las correlaciones genéticas entre edades de selección en un ensayo clonal en el municipio de Botucatu, SP. El experimento fue instalado en un diseño de bloques completos al azar, siendo 23 clones (21 tratamientos y 2 testigos, repetidas 4 veces. Las parcelas fueron formadas por 25 plantas con distanciamiento de 3,0 x 2,0 m. Las características silviculturales como altura de planta, diámetro a la altura del pecho – DAP y volumen de madera fueron evaluadas a los 24, 36, 48 e 60 meses después del plantío. El análisis de los parámetros genéticos fue realizado con el programa estadístico GENES. Diferencias significativas fueron observadas para todos los caracteres en el análisis. Correlaciones altas y significativas fueron observadas entre los caracteres, indicando que la selección precoz puede proporcionar ganancias genéticas de hasta 34%. Los clones 18, 20 e 22 presentaron las mayores estimativas para volumen de madeira, demostrando potencial para ser aprovechado en los programas de mejoramiento genético y en plantíos comerciales, proporcionando buenos niveles de productividad para la región de Botucatu, SP.This work deals with the study of estimates of quantitative genetic parameters in a clonal assay for the early selection of superior clones of Eucalyptus and subsequent commercial planting. Thus, the aim of this study was to estimate the genetic variability and to determine the genetic correlations between the ages of clonal selection in a trial in the city of Botucatu, SP. The experiment was installed in a completely randomized design blocks (4 and 23 clones (21 treatment and 2 controls. The plots were formed by 25 plants with spacing of 3

  18. Individual Differences in Fifth Graders' Literacy and Academic Language Predict Comprehension Monitoring Development: An Eye-Movement Study

    Science.gov (United States)

    Connor, Carol McDonald; Radach, Ralph; Vorstius, Christian; Day, Stephanie L.; McLean, Leigh; Morrison, Frederick J.

    2015-01-01

    In this study, we investigated fifth graders' (n = 52) fall literacy, academic language, and motivation and how these skills predicted fall and spring comprehension monitoring on an eye movement task. Comprehension monitoring was defined as the identification and repair of misunderstandings when reading text. In the eye movement task, children…

  19. How dogs scan familiar and inverted faces: an eye movement study.

    Science.gov (United States)

    Somppi, Sanni; Törnqvist, Heini; Hänninen, Laura; Krause, Christina M; Vainio, Outi

    2014-05-01

    Faces play an important role in communication and identity recognition in social animals. Domestic dogs often respond to human facial cues, but their face processing is weakly understood. In this study, facial inversion effect (deficits in face processing when the image is turned upside down) and responses to personal familiarity were tested using eye movement tracking. A total of 23 pet dogs and eight kennel dogs were compared to establish the effects of life experiences on their scanning behavior. All dogs preferred conspecific faces and showed great interest in the eye area, suggesting that they perceived images representing faces. Dogs fixated at the upright faces as long as the inverted faces, but the eye area of upright faces gathered longer total duration and greater relative fixation duration than the eye area of inverted stimuli, regardless of the species (dog or human) shown in the image. Personally, familiar faces and eyes attracted more fixations than the strange ones, suggesting that dogs are likely to recognize conspecific and human faces in photographs. The results imply that face scanning in dogs is guided not only by the physical properties of images, but also by semantic factors. In conclusion, in a free-viewing task, dogs seem to target their fixations at naturally salient and familiar items. Facial images were generally more attractive for pet dogs than kennel dogs, but living environment did not affect conspecific preference or inversion and familiarity responses, suggesting that the basic mechanisms of face processing in dogs could be hardwired or might develop under limited exposure.

  20. In vivo, Ex Vivo, and In Vitro Approaches to Study Intermediate Filaments in the Eye Lens.

    Science.gov (United States)

    Jarrin, Miguel; Young, Laura; Wu, Weiju; Girkin, John M; Quinlan, Roy A

    2016-01-01

    The role of the eye lens is to focus light into the retina. To perform this unique function, the ocular lens must be transparent. Previous studies have demonstrated the expression of vimentin, BFSP1, and BFSP2 in the eye lens. These intermediate filament (IF) proteins are essential to the optical properties of the lens. They are also important to its biomechanical properties, to the shape of the lens fiber cells, and to the organization and function of the plasma membrane. The eye lens is an iconic model in developmental studies, as a result different vertebrate models, including zebrafish, have been developed to study lens formation. In the present chapter, we have summarized the new approaches and the more breakthrough models (e.g., iPSc) that can be used to study the function of IFs in the ocular lens. We have presented three different groups of models. The first group includes in vitro models, where IFs can be studied and manipulated in lens cell cultures. The second includes ex vivo models. These replicate better the complex lens cell differentiation processes and the role(s) played by IFs. The third class is the in vivo models, and here, we have focused on Zebrafish and new imaging approaches using selective plane illumination microscopy. Finally, we present protocols on how to use these lens models to study IFs.

  1. An Eye-tracking Study of Notational, Informational, and Emotional Aspects of Learning Analytics Representations

    DEFF Research Database (Denmark)

    Vatrapu, Ravi; Reimann, Peter; Bull, Susan;

    2013-01-01

    This paper presents an eye-tracking study of notational, informational, and emotional aspects of nine different notational systems (Skill Meters, Smilies, Traffic Lights, Topic Boxes, Collective Histograms, Word Clouds, Textual Descriptors, Table, and Matrix) and three different information state...... of learning analytics representations and discourse environments are discussed....... (Weak, Average, & Strong) used to represent student's learning. Findings from the eye-tracking study show that higher emotional activation was observed for the metaphorical notations of traffic lights and smilies and collective representations. Mean view time was higher for representations...... of the "average" informational learning state. Qualitative data analysis of the think-aloud comments and post-study interview show that student participants reflected on the meaning-making opportunities and action-taking possibilities afforded by the representations. Implications for the design and evaluation...

  2. Evaluation of Color Settings in Aerial Images with the Use of Eye-Tracking User Study

    Science.gov (United States)

    Mirijovsky, J.; Popelka, S.

    2016-06-01

    The main aim of presented paper is to find the most realistic and preferred color settings for four different types of surfaces on the aerial images. This will be achieved through user study with the use of eye-movement recording. Aerial images taken by the unmanned aerial system were used as stimuli. From each image, squared crop area containing one of the studied types of surfaces (asphalt, concrete, water, soil, and grass) was selected. For each type of surface, the real value of reflectance was found with the use of precise spectroradiometer ASD HandHeld 2 which measures the reflectance. The device was used at the same time as aerial images were captured, so lighting conditions and state of vegetation were equal. The spectral resolution of the ASD device is better than 3.0 nm. For defining the RGB values of selected type of surface, the spectral reflectance values recorded by the device were merged into wider groups. Finally, we get three groups corresponding to RGB color system. Captured images were edited with the graphic editor Photoshop CS6. Contrast, clarity, and brightness were edited for all surface types on images. Finally, we get a set of 12 images of the same area with different color settings. These images were put into the grid and used as stimuli for the eye-tracking experiment. Eye-tracking is one of the methods of usability studies and it is considered as relatively objective. Eye-tracker SMI RED 250 with the sampling frequency 250 Hz was used in the study. As respondents, a group of 24 students of Geoinformatics and Geography was used. Their task was to select which image in the grid has the best color settings. The next task was to select which color settings they prefer. Respondents' answers were evaluated and the most realistic and most preferable color settings were found. The advantage of the eye-tracking evaluation was that also the process of the selection of the answers was analyzed. Areas of Interest were marked around each image in the

  3. Trabalho em turnos nas empresas de Botucatu, São Paulo: estudo descritivo

    Directory of Open Access Journals (Sweden)

    Miguel Angelo Rosa Martinez

    Full Text Available Em face da inexistência de dados sobre esquema de trabalho em turnos em empresas de Botucatu, solicitaram-se delas informações sobre ramo de atividade, número de funcionários e esquema de trabalho. Às que registraram tal ocorrência, enviou-se um questionário visando à caracterização da forma de organização da jornada de trabalho. Das 66 empresas participantes da pesquisa, 14 referiram a existência de trabalho em turnos, englobando 6.541 funcionários, de um total de 9.502, sendo 2.346 de setores da produção. Nesses setores, os sistemas contínuo alternado e descontínuo permanente predominaram. Em oito empresas os sistemas eram alternados, cinco delas com esquemas apresentando freqüência de revezamento de seis ou mais dias. São descritas outras formas de organização encontradas. Conclui-se que, com o quadro descrito, torna-se possível estudar as relações entre trabalho em turnos, saúde e vida social dos trabalhadores.

  4. Some predictors of cardiovascular mortality among the elderly population of Botucatu (SP

    Directory of Open Access Journals (Sweden)

    Ruiz Tania

    2001-01-01

    Full Text Available OBJECTIVE: To detect factors associated with cardiovascular mortality in the elderly of Botucatu. METHODS: We evaluated 29 variables of interest in a cohort of patients aged ³60 using data from a survey conducted between 1983/84. The elderly cohort was analyzed in 1992 to detect the occurrence of cardiovascular deaths. Survival analysis was performed using the Kaplan-Meier method, the log-rank test, and Cox regression analysis. Three models were adapted for each group of variables, and a final model was chosen from those variables selected from each group. RESULTS: We identified predictor for cardiovascular death according to age for elderly males not supporting the family, not possessing a vehicle, and previous cardiovascular disease. In elderly females, the predictor variables were previous cardiovascular disease and diabetes mellitus. CONCLUSION: Socioeconomic indicators (family heading and vehicle ownerrship may be added to well stabilished medical factors (diabete mellitus and hypertension to select target groups for programs intended to reduce deaths due to cardiovascular diseases in elderly people.

  5. Rabies in the big fruit-esting bat Artibeus lituratus from Botucatu, Southeastern Brazil

    Directory of Open Access Journals (Sweden)

    H. Langoni

    2005-03-01

    Full Text Available Rabies is a viral disease of mammals transmitted through the bite of a rabid animal. A frugivorous adult male bat, Artibeus lituratus, family Phyllostomidae, was diagnosed as positive to rabies by direct immunofluorescence (DIF and mouse inoculation test (MIT of the bat's brain, both performed at the School of Veterinary Medicine and Animal Husbandry - FMVZ, UNESP, Botucatu, São Paulo State, Brazil. The animal collided with the window of a commercial establishment in the urban area during the day. With regard to DIF, a high amount of Negri bodies of several sizes was observed in the brain. The spleen and right kidney presented some Negri bodies too. In relation to MIT, the mice presented paralysis in the 7th day, and died in the day after with several characteristic small bodies. The reverse transcriptase-polymerase chain reaction (RT-PCR, followed by hemi-nested RT-PCR (hnRT-PCR resulted in an amplification of fragments from the bat's brain viral RNA, 432bp in RT-PCR, and 274bp in hnRT-PCR, confirming the diagnosis. Therefore, the hnRT-PCR and DIF have good sensitivity and specificity, providing and confirming the diagnosis of the clinical samples in a short period of time.

  6. Eye Diseases

    Science.gov (United States)

    ... the back of the eye Macular degeneration - a disease that destroys sharp, central vision Diabetic eye problems ... defense is to have regular checkups, because eye diseases do not always have symptoms. Early detection and ...

  7. Eye Injuries

    Science.gov (United States)

    The structure of your face helps protect your eyes from injury. Still, injuries can damage your eye, sometimes severely enough that you could lose your vision. Most eye injuries are preventable. If you play sports or ...

  8. Eye Wear

    Science.gov (United States)

    Eye wear protects or corrects your vision. Examples are Sunglasses Safety goggles Glasses (also called eyeglasses) Contact ... jobs and some sports carry a risk of eye injury. Thousands of children and adults get eye ...

  9. Eye Cancer

    Science.gov (United States)

    Cancer of the eye is uncommon. It can affect the outer parts of the eye, such as the eyelid, which are made up ... adults are melanoma and lymphoma. The most common eye cancer in children is retinoblastoma, which starts in ...

  10. Eye proprioception may provide real time eye position information.

    Science.gov (United States)

    Wang, Jing; Pan, Yujun

    2013-03-01

    Because of the frequency of eye movements, online knowledge of eye position is crucial for the accurate spatial perception and behavioral navigation. Both the internal monitoring signal (corollary discharge) of eye movements and the eye proprioception signal are thought to contribute to the localization of the eye position in the orbit. However, the functional role of these two eye position signals in spatial cognition has been disputed for more than a century. The predominant view proposes that the online analysis of eye position is exclusively provided by the corollary discharge signal, while the eye proprioception signal only plays a role in the long-term calibration of the oculomotor system. However, increasing evidence from recent behavioral and physiological studies suggests that the eye proprioception signal may play a role in the online monitoring of eye position. The purpose of this review is to discuss the feasibility and possible function of the eye proprioceptive signal for online monitoring of eye position.

  11. Analysis of Gnostic Actions Using Eye Tracking as a Method of Studying Insight in Problem Solving

    Directory of Open Access Journals (Sweden)

    Vladimirov I.Yu.,

    2016-04-01

    Full Text Available TThe paper focuses on the issue of research methods in studying insight. Since the process of insight is quite difficult to verbalize, researchers are presented with the methodological challenge of its objectifica- tion. One of the possible methods is the analysis of gnostic actions as components of a single integrated system of perceptive and thinking activity aimed at problem solving. The paper analyzes past and present periods in the explorations of insight with this method and suggests that eye tracking in problem solving is the most perspective technology. It reviews the studies of G. Knoblich, J. Ellis, E, Grant and M. Spivey, L. Thomas and A. Lleras, D. Kahneman, J.T. Wang and others. The paper compares various characteristics of eye movements and their content and discusses perspectives for the study on insight using the method of eye movement tracking, that is, testing the theoretical assumptions concerning the mechanisms of insight in problem solving and revealing the processes underlying insight.

  12. The disengagement of visual attention in people with Alzheimer's Disease: A longitudinal eye-tracking study

    Directory of Open Access Journals (Sweden)

    Trevor J Crawford

    2015-06-01

    Full Text Available IntroductionEye tracking provides a convenient and promising biological marker of cognitive impairment in patients with neurodegenerative disease. Here we report a longitudinal study of saccadic eye movements in a sample of patients with dementia and elderly control participants who were assessed at start of the study and followed up 12 months later.MethodsEye movements were measured in the standard gap and overlap paradigms, to examine the longitudinal trends in the ability to disengage attention from a visual target.ResultsOverall patients with dementia had slower reaction times than the control group. However, after 12 months, both groups showed faster and comparable reductions in reaction times to the gap, compared to the overlap stimulus. Interestingly, there was a general improvement for both groups with more accurately directed saccades and speeding of reaction times after 12 months.ConclusionsThese findings point to the value of longer-term studies and follow-up assessment to ascertain the effects of dementia on oculomotor control.

  13. [Raman spectra study of thermal transformation of nephrite cat's eye from Sichuan province].

    Science.gov (United States)

    Lu, Bao-qi; Xia, Yi-ben; Qi, Li-jian; You, Jing-lin

    2005-11-01

    Raman spectrum and X-ray powder diffraction (XRD) were used to study the process andproduct of thermal transformation of nephrite cat's eye from Sichuan province. The results indicate that upon being heated till 900 degrees C, tremolite in the nephrite cat's eye is dehydrated completely and the appearance of a new characteristic band near 671 cm(-1) indicates the form of a new product. At 1 000 degrees C, the intensity of band near 1014 cm(-1) rises obviously, and the weak bands near 573 cm(-1) and 934 cm(-1) present. Up to 1100 degrees C, the band near 1033 cm(-1) appears. All these evidences show that the final thermal transformation product is identified as Ca-Mg pyroxene which is similar to diopside both in structure and in composition. This conclusion is confirmed by XRD.

  14. Physical activity in childhood and the association with myopia in adolescence – The CHAMPS Eye Study

    DEFF Research Database (Denmark)

    Lundberg, Lars Kristian; Vestergaard, Anders Højslet; Jacobsen, Nina

    Purpose: Myopia is the most frequent eye disease globally and is usually caused by increasing axial growth of the eye during childhood and adolescence. Lifestyle changes such as reduced physical activity (PA) are thought to be the driving force behind the rapid increase of myopia worldwide......-PA prompt a 0.3 mm longer AL (Pphysical activity was associated with a shorter axial length and refractive error for SED-PA and M-PA, consistent with theory....... cohort (Childhood Health, Activity, and Motor Performance School Study Denmark). PA was assessed with GT3X accelerometer (ActiGraph, Florida, USA) worn for 7 full consecutive days at the period August to October 2010: mean intensity was estimated as counts/min (CPM); and cut off-points for sedentary (SED...

  15. Visual exploration patterns of human figures in action: an eye tracker study with art paintings.

    Science.gov (United States)

    Villani, Daniela; Morganti, Francesca; Cipresso, Pietro; Ruggi, Simona; Riva, Giuseppe; Gilli, Gabriella

    2015-01-01

    Art exploration is a complex process conditioned by factors at different levels and includes both basic visual principles and complex cognitive factors. The human figure is considered a critical factor attracting the attention in art painting. Using an eye-tracking methodology, the goal of this study was to explore different elements of the human figure performing an action (face and body parts in action) in complex social scenes characterized by different levels of social interaction between agents depicted in scenes (individual vs. social). The sample included 44 laypersons, and the stimuli consisted of 10 fine art paintings representing the figurative style of classical art. The results revealed different scanning patterns of the human figure elements related to the level of social interaction of agents depicted in the scene. The agents' face attracted eye movements in social interaction scenes while the agents' body parts attracted eye movements only when the agents were involved in individual actions. These processes were confirmed specifically in participants with high empathic abilities who became immediately fixated on faces to develop a mimetic engagement with other agents. Future studies integrating other measures would help confirm the results obtained and strengthen their implication for embodiment processes.

  16. The Added Value of Eye-tracking in Diagnosing Dyscalculia: A Case Study

    Directory of Open Access Journals (Sweden)

    Sietske eVan Viersen

    2013-10-01

    Full Text Available The present study compared eye movements and performance of a nine-year-old girl with Developmental Dyscalculia (DD on a series of number line tasks to those of a group of typically developing (TD children (n = 10, in order to answer the question whether eye-tracking data from number line estimation tasks can be a useful tool to discriminate between TD children and children with a number processing deficit. Quantitative results indicated that the child with dyscalculia performed worse on all symbolic number line tasks compared to the control group, indicated by a low linear fit (R2 and a low accuracy measured by mean percent absolute error. In contrast to the control group, her magnitude representations seemed to be better represented by a logarithmic than a linear fit. Furthermore, qualitative analyses on the data of the child with dyscalculia revealed more unidentifiable fixation patterns in the processing of multi-digit numbers and more dysfunctional estimation strategy use in one third of the estimation trials as opposed to approximately 10% in the control group. In line with her dyscalculia diagnosis, these results confirm the difficulties with spatially representing and manipulating numerosities on a number line, resulting in inflexible and inadequate estimation or processing strategies. It can be concluded from this case study that eye-tracking data can be used to discern different number processing and estimation strategies in TD children and children with a number processing deficit. Hence, eye-tracking data in combination with number line estimation tasks might be a valuable and promising addition to current diagnostic measures.

  17. The added value of eye-tracking in diagnosing dyscalculia: a case study.

    Science.gov (United States)

    van Viersen, Sietske; Slot, Esther M; Kroesbergen, Evelyn H; Van't Noordende, Jaccoline E; Leseman, Paul P M

    2013-01-01

    The present study compared eye movements and performance of a 9-year-old girl with Developmental Dyscalculia (DD) on a series of number line tasks to those of a group of typically developing (TD) children (n = 10), in order to answer the question whether eye-tracking data from number line estimation tasks can be a useful tool to discriminate between TD children and children with a number processing deficit. Quantitative results indicated that the child with dyscalculia performed worse on all symbolic number line tasks compared to the control group, indicated by a low linear fit (R (2)) and a low accuracy measured by mean percent absolute error. In contrast to the control group, her magnitude representations seemed to be better represented by a logarithmic than a linear fit. Furthermore, qualitative analyses on the data of the child with dyscalculia revealed more unidentifiable fixation patterns in the processing of multi-digit numbers and more dysfunctional estimation strategy use in one third of the estimation trials as opposed to ~10% in the control group. In line with her dyscalculia diagnosis, these results confirm the difficulties with spatially representing and manipulating numerosities on a number line, resulting in inflexible and inadequate estimation or processing strategies. It can be concluded from this case study that eye-tracking data can be used to discern different number processing and estimation strategies in TD children and children with a number processing deficit. Hence, eye-tracking data in combination with number line estimation tasks might be a valuable and promising addition to current diagnostic measures.

  18. Análise da frequência anual das condições de céu em Botucatu, São Paulo Analysis of the annual frequency of the sky conditions in Botucatu, São Paulo

    Directory of Open Access Journals (Sweden)

    Érico T. Teramoto

    2012-09-01

    Full Text Available Este trabalho apresenta uma análise da frequência das condições de céu em Botucatu. A classificação das condições de céu foi feita com base no índice de claridade (K T, calculado a partir de uma base de dados de 10 anos de radiação global diária. Em Botucatu há, ao longo do ano, predominância de dias com condição de céu claro, em média 114 dias. Para a condição de céu nebuloso a frequência média é de 61 dias e, em referência às duas condições de céu intermediárias, a frequência de céu parcialmente nebuloso com dominância para o difuso, é de 94 dias e a com dominância para o claro é de 96 dias. Os principais fatores influentes sobre as condições de céu em Botucatu são as entradas de frentes frias e a formação da Zona de Convergência do Atlântico Sul, as quais respondem principalmente pela alteração da condição de céu claro para a de céu nebuloso ou para a de céu parcialmente nebuloso com dominância para o difuso. Os aerossóis resultantes das queimadas em lavouras de cana-de-açúcar respondem pela alteração da condição de céu claro para a de céu parcialmente nebuloso com dominância para o claro.This paper presents an analysis of the frequency of the sky conditions in Botucatu. The classification of sky conditions was made based on the clearness index (K T, calculated from a database with 10 years of measured daily global solar radiation. Throughout the year in Botucatu, there is a predominance of days with clear sky condition, on average 114 days. For cloudy sky condition, the average frequency is 61 days. About the two intermediate sky conditions, the frequency of the sky partially cloudy with dominance for the diffuse is 94 days and the one with dominance for the clear is 96 days. The main influential factors on the sky conditions in Botucatu are the inputs of cold fronts and the formation of the South Atlantic Convergence Zone. They respond primarily by altering the sky condition of

  19. Análise das condições de saúde e de vida da população urbana de Botucatu, SP: I - Descrição do plano amostral e avaliação da amostra Analysis of standards of living and health in the urban population of Botucatu, S.Paulo State (Brazil: I - Description and evaluation of the sample

    Directory of Open Access Journals (Sweden)

    Luana Carandina

    1986-12-01

    Full Text Available Descreve-se o processo de amostragem para o levantamento das condições de saúde e de vida da população urbana de Botucatu, SP (Brasil, pelo método de entrevistas domiciliárias. Analisa-se a representatividade da amostra, segundo a distribuição percentual da população por estrato e segundo as variáveis sexo e idade. Comparam-se os critérios externos de estratificação sócio-econômica com a renda familiar e per capita das famílias entrevistadas. Comenta-se as dificuldades de operacionalizar o conceito de classe social através de zonas sócio-espaciais, em investigações domiciliares e em estudos epidemiológicos que utilizam dados de registro rotineiros.The sampling methodology used in an evaluation of the standards of living and health in the urban population of Botucatu, SP, Brazil is discribed. Data were obtained through domiciliar interviews and the accuracy of sampling was evaluated for each different stratum and in accord with age and sex. External criteria for socio-economic stratification of the population such as family or "per capita" income were compared. It was found difficult to work with the concept of social classes when using socio-spacial zoning in domiciliar interviews or epidemiological studies based on the normal registers.

  20. Changes in intraocular pressure in study and fellow eyes in the IVAN trial

    Science.gov (United States)

    Foss, Alexander J E; Scott, Lauren J; Rogers, Chris A; Reeves, Barney C; Ghanchi, Faruque; Gibson, Jonathan; Chakravarthy, Usha

    2016-01-01

    Purpose To describe changes in intraocular pressure (IOP) in the ‘alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN)’ trial (registered as ISRCTN92166560). Design Randomised controlled clinical trial with factorial design. Participants Patients (n=610) with treatment naïve neovascular age-related macular degeneration were enrolled and randomly assigned to receive either ranibizumab or bevacizumab and to two regimens, namely monthly (continuous) or as needed (discontinuous) treatment. Methods At monthly visits, IOP was measured preinjection in both eyes, and postinjection in the study eye. Outcome measures The effects of 10 prespecified covariates on preinjection IOP, change in IOP (postinjection minus preinjection) and the difference in preinjection IOP between the two eyes were examined. Results For every month in trial, there was a statistically significant rise in both the preinjection IOP and the change in IOP postinjection during the time in the trial (estimate 0.02 mm Hg, 95% CI 0.01 to 0.03, p<0.001 and 0.03 mm Hg, 95% CI 0.01 to 0.04, p=0.002, respectively). There was also a small but significant increase during the time in trial in the difference in IOP between the two eyes (estimate 0.01 mm Hg, 95% CI 0.005 to 0.02, p<0.001). There were no differences between bevacizumab and ranibizumab for any of the three outcomes (p=0.93, p=0.22 and p=0.87, respectively). Conclusions Anti-vascular endothelial growth factor agents induce increases in IOP of small and uncertain clinical significance. Trial registration number ISRCTN92166560. PMID:27073205

  1. Self-Face Recognition in Schizophrenia: An Eye-Tracking Study.

    Science.gov (United States)

    Bortolon, Catherine; Capdevielle, Delphine; Salesse, Robin N; Raffard, Stéphane

    2016-01-01

    Self-face recognition has been shown to be impaired in schizophrenia (SZ), according to studies using behavioral tasks implicating cognitive demands. Here, we employed an eye-tracking methodology, which is a relevant tool to understand impairments in self-face recognition deficits in SZ because it provides a natural, continuous and online record of face processing. Moreover, it allows collecting the most relevant and informative features each individual looks at during the self-face recognition. These advantages are especially relevant considering the fundamental role played by the patterns of visual exploration on face processing. Thus, this paper aims to investigate self-face recognition deficits in SZ using eye-tracking methodology. Visual scan paths were monitored in 20 patients with SZ and 20 healthy controls. Self, famous, and unknown faces were morphed in steps of 20%. Location, number, and duration of fixations on relevant areas were recorded with an eye-tracking system. Participants performed a passive exploration task (no specific instruction was provided), followed by an active decision making task (individuals were explicitly requested to recognize the different faces). Results showed that patients with SZ had fewer and longer fixations compared to controls. Nevertheless, both groups focused their attention on relevant facial features in a similar way. No significant difference was found between groups when participants were requested to recognize the faces (active task). In conclusion, using an eye tracking methodology and two tasks with low levels of cognitive demands, our results suggest that patients with SZ are able to: (1) explore faces and focus on relevant features of the face in a similar way as controls; and (2) recognize their own face.

  2. Influence of aspheric intraocular lens on frequency doubling technology and contrast sensitivity: a fellow eye study

    Directory of Open Access Journals (Sweden)

    Rodrigo França de Espíndola

    2014-12-01

    Full Text Available Purpose: To evaluate whether implantation of an aspheric intraocular lens (IOL results in reduced ocular aberrations and improved contrast sensitivity after cataract surgery and, therefore, changes on frequency-doubling technology (FDT testing. Methods: The present prospective clinical study enrolled 25 patients with bilateral cataract (50 eyes, who randomly received either an aspheric (Akreos AO or a spherical (Akreos Fit IOL in one eye and the other IOL in the second eye. Assessment 12 months postoperatively included photopic and mesopic contrast sensitivity testing. Higher-order aberrations (HOAs were computed. FDT testing was divided into four areas to evaluate the variation of the values at different points. The median values of the local pattern thresholds (median area contrast sensitivity [MACS] obtained with that division were calculated. Results: The Akreos AO group obtained statistically significantly lower values of HOAs and spherical aberration compared with the Akreos Fit group. There was a statistically significant between-group difference in contrast sensitivity under mesopic conditions at all spatial frequencies. No statistically significant differences were observed in mean deviation and pattern standard deviation. The aspheric IOL exhibited higher MACS in all areas, although a statistically significant difference was reached only in the 20-degree field area (P=0.043. Conclusion: Aspheric IOLs significantly reduced spherical aberration and HOAs, improving mesopic contrast sensitivity. Although there was a trend toward slightly improved FDT in the aspheric IOL group, it was not statistically significant.

  3. Visual social attention in autism spectrum disorder: insights from eye tracking studies.

    Science.gov (United States)

    Guillon, Quentin; Hadjikhani, Nouchine; Baduel, Sophie; Rogé, Bernadette

    2014-05-01

    We review different aspects of visual social attention in autism spectrum disorders (ASD) from infancy to adulthood in light of the eye-tracking literature. We first assess the assumption that individuals with ASD demonstrate a deficit in social orienting together with decreased attention to socially relevant stimuli such as faces compared to TD individuals. Results show that social orienting is actually not qualitatively impaired and that decreased attention to faces does not generalized across contexts. We also assess the assumption that individuals with ASD demonstrate excess mouth and diminished eye gaze compared to TD individuals. We find that this assumption receives little support across ages and discuss some factors that might have initially lead to this conjecture. We report that the assessment of the ability to follow the direction of another person's gaze needs to be further examined and that eye-tracking studies add to the evidence that individuals with ASD demonstrate difficulties in interpreting gaze cues. Finally, we highlight innovative data acquisition and analyses that are increasingly shedding light on the more subtle nature of the profound social difficulties experienced by individuals with ASD.

  4. Eye movements as an index of pathologist visual expertise: a pilot study.

    Directory of Open Access Journals (Sweden)

    Tad T Brunyé

    Full Text Available A pilot study examined the extent to which eye movements occurring during interpretation of digitized breast biopsy whole slide images (WSI can distinguish novice interpreters from experts, informing assessments of competency progression during training and across the physician-learning continuum. A pathologist with fellowship training in breast pathology interpreted digital WSI of breast tissue and marked the region of highest diagnostic relevance (dROI. These same images were then evaluated using computer vision techniques to identify visually salient regions of interest (vROI without diagnostic relevance. A non-invasive eye tracking system recorded pathologists' (N = 7 visual behavior during image interpretation, and we measured differential viewing of vROIs versus dROIs according to their level of expertise. Pathologists with relatively low expertise in interpreting breast pathology were more likely to fixate on, and subsequently return to, diagnostically irrelevant vROIs relative to experts. Repeatedly fixating on the distracting vROI showed limited value in predicting diagnostic failure. These preliminary results suggest that eye movements occurring during digital slide interpretation can characterize expertise development by demonstrating differential attraction to diagnostically relevant versus visually distracting image regions. These results carry both theoretical implications and potential for monitoring and evaluating student progress and providing automated feedback and scanning guidance in educational settings.

  5. The effect of human image in B2C website design: an eye-tracking study

    Science.gov (United States)

    Wang, Qiuzhen; Yang, Yi; Wang, Qi; Ma, Qingguo

    2014-09-01

    On B2C shopping websites, effective visual designs can bring about consumers' positive emotional experience. From this perspective, this article developed a research model to explore the impact of human image as a visual element on consumers' online shopping emotions and subsequent attitudes towards websites. This study conducted an eye-tracking experiment to collect both eye movement data and questionnaire data to test the research model. Questionnaire data analysis showed that product pictures combined with human image induced positive emotions among participants, thus promoting their attitudes towards online shopping websites. Specifically, product pictures with human image first produced higher levels of image appeal and perceived social presence, thus stimulating higher levels of enjoyment and subsequent positive attitudes towards the websites. Moreover, a moderating effect of product type was demonstrated on the relationship between the presence of human image and the level of image appeal. Specifically, human image significantly increased the level of image appeal when integrated in entertainment product pictures while this relationship was not significant in terms of utilitarian products. Eye-tracking data analysis further supported these results and provided plausible explanations. The presence of human image significantly increased the pupil size of participants regardless of product types. For entertainment products, participants paid more attention to product pictures integrated with human image whereas for utilitarian products more attention was paid to functional information of products than to product pictures no matter whether or not integrated with human image.

  6. Avaliação das perdas de manga (Mangifera indica L. no mercado varejista da cidade de Botucatu-SP Mango losses estimate in retail market

    Directory of Open Access Journals (Sweden)

    José Matheus Yalenti Perosa

    2009-09-01

    Full Text Available O elevado percentual de perdas na comercialização de manga no Brasil faz com que apenas parcela da produção chegue à mesa do consumidor. O presente trabalho determinou, em equipamentos de varejo da cidade de Botucatu - SP, as perdas de manga, suas causas e emitir sugestões para a redução das mesmas. Foram selecionados 22 equipamentos entre supermercados, quitanda/sacolões e feiras livres. O volume estimado de manga comercializada neste município foi 114 t/ano. Verificaram-se as seguintes perdas médias por variedade de manga: 11,5% para 'Tommy Atkins', 12,4% para 'Haden' e 12,7% para as outras variedades. O valor total anual destas perdas no comércio varejista da cidade, em 2007, atingiu R$ 49.200,00 (US$ 25.231,00, correspondente a 14 toneladas. Os percentuais médios de perda mostram grande semelhança quando comparados a estudos realizados em outras localidades. Os resultados obtidos apontam para a necessidade de melhor gestão de estoques, de exposição da fruta para o consumidor e uso de tecnologia no transporte e armazenagem para a manutenção da qualidade e redução das perdas. Conclui-se também pela necessidade de maiores investimentos em capacitação técnica dos encarregados do setor de frutas e hortaliças.Losses in the mango commercialization process in Brazil has reduced its offer to the consumer. The present study aims at determining these losses in different purchase sites of the retail market, its causes and suggestions for reducing them. Twenty two retail points, including supermarkets, greengroceries and free fair were selected in Botucatu, state of São Paulo, Brazil. The total amount commercialized was 114 ton/year. The following average losses were verified for each mango variety: 'Tommy Atkins' (11, 5%, Haden (12, 4% and 12, 7% for other varieties. The total loss in retail market reached US$ 25.231, 00 corresponding to 14 tons. The average loss percentage observed is compatible with previous studies running

  7. Epidemiological aspects of enteroparasitosis at daycare centers in the city of Botucatu, State of São Paulo, Brazil Aspectos epidemiológicos das enteroparasitoses em creches na cidade de Botucatu, Estado de São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    Luciene Maura Mascarini

    2006-09-01

    Full Text Available OBJECTIVE: To estimate the prevalence and incidence of intestinal parasites in children and staff members of 5 municipal daycare centers in Botucatu/SP. Two cross-sectional studies were carried out in 2002 (N=379 and 2003 (N=397 and a longitudinal observational experiment in which the children from 2002 and 2003 were evaluated for a year. Questionnaires were given to staff members and parents of the children, where the following variables were recorded: socioeconomic status, sanitary habits, home, age, gender and presence of domestic animals. Coproparasitologic tests were carried out in child daycare centers. The enteroparasite prevalence was 76.74% in 2002 and 34% in 2003. The variables associated with presence of enteroparasites in the investigation carried out in 2002 were: location of daycare centers (OR=0.27 CI=0.15-0.47; family salary (OR=4.38 CI=1.91-10.04; gender (OR=0.52 CI=0.32-0.85; child's age group (OR=2.08 CI=1.06-4.08, and presence of pets at home (OR=1.85 CI=1.10-3.11; in 2003, the variables were: daycare centers located in peripheral region (OR=0.49 CI=0.31-0.78, family salary (OR=3.69 CI=2.19-6.24; mother's education (OR=6.19 CI=1.81-21.21; gender (OR=0.58 CI=0.36-0.93, and presence of pets (OR=1.68 CI=1.01-2.79. The cohort had 253 children with an incidence of 23.22%. Data from this study highlighted situations of risk in specific populations (daycare centers, which could be useful for other childcare institutions.Estimou-se a prevalência e a incidência de parasitas intestinais em crianças e funcionários de 5 creches municipais em Botucatu/SP. Foram realizados dois estudos seccionais em 2002 (N=379 e 2003 (N=397 e um estudo longitudinal observacional, onde as crianças de 2002 e 2003 foram seguidas por um ano. Foram aplicados questionários nos funcionários e nos pais das crianças, onde foram coletadas as seguintes variáveis: nível sócio-econômico, hábitos sanitários, moradia, idade, sexo e presença de animais dom

  8. Prevalence of Cataract Surgery and Visual Outcomes in Indian Immigrants in Singapore: The Singapore Indian Eye Study

    OpenAIRE

    Preeti Gupta; Yingfeng Zheng; Tay Wan Ting; Ecosse L Lamoureux; Ching-Yu Cheng; Tien-Yin Wong

    2013-01-01

    OBJECTIVE: To determine the prevalence of cataract surgery and factors associated with post-surgical visual outcomes in migrant Indians living in Singapore. RESEARCH DESIGN AND METHODS: We conducted a population-based study in 3,400 Indian immigrants residing in Singapore-the Singapore Indian Eye Study (SINDI). All participants underwent comprehensive medical eye examination and a standardized interview. Post-operative visual impairment (VI) was defined as best-corrected or presenting visual ...

  9. Taxa de absorção atmosférica sobre as cidades de Botucatu-SP e Rio de Janeiro-RJ Atmospheric absorption ratio on the cities of Botucatu-SP and Rio de Janeiro-RJ

    Directory of Open Access Journals (Sweden)

    Nelson Veissid

    2010-12-01

    October 23, 1998 and it hosts on board a solar cell experiment. Silicon solar cell is a semiconductor device that senses visible and near infrared (400-1100 nm radiations. The experiment permits the simultaneous inference of direct insolation and the insolation that is reflected outside of Earth. The data of the solar cell experiment are transmitted in real time by the satellite telemetry and are received by the ground station of Cuiabá, MT-Brazil (16°S, 56°W. This fact limits their spatial coverage to a circle on the South America. The planetary albedo is obtained inside this coverage area and the data can be grouped into periods of time (annual, seasonal or monthly or studied for several places (latitude and longitude during the life of the satellite. Atmospheric transmission coefficient or clearness index (Kt, measured at meteorological stations around the Earth surface, together with simultaneous measured of the planetary albedo permits to calculate the atmospheric absorption coefficient (Ka. The developed method in this work for evaluating the Ka considers that the planetary albedo is composed by two parts: the local and the non local reflectivity. Considering this new concept, an atmospheric absorption ratio (called here Ra is defined as the quotient between Ka and the net solar irradiance power that is not transmitted through the atmosphere (100%-Kt. The atmospheric absorption ratio defined by this way is not cloud cover dependent. The frequency histogram of Ra indicates the values of 0.86±0.07 and 0.88±0.09 on the cities of Botucatu-SP and Rio de Janeiro-RJ respectively, during the years of 1999 to 2006.

  10. A clinical study of the efficacy of topical corticosteroids on dry eye

    Institute of Scientific and Technical Information of China (English)

    YANG Chong-qing; SUN Wen; GU Yang-shun

    2006-01-01

    Objective: To evaluate the effect of topical corticosteroid for treatment of moderate or severe dry eye. Methods: Sixty eyes of 30 patients with moderate or severe dry eye, who were not sensitive to artificial tears, were treated with 0.1% fluorometholone eye drops. Subjective symptom and objective tests were used to evaluate the efficacy of treatment before and after application of 0.1% fluorometholone eye drops for 1 week and 1 month. Side effects were also evaluated. Results: After 1 week of treatment, subjective symptoms were improved in all dry eye patients; objective tests were improved in all dry eye patients 1month after treatment, and the difference was significant. Conclusion: Topical corticosteroid drops can rapidly and effectively relieve the symptoms and signs of moderate or severe dry eye.

  11. Metabolic syndrome in overweight children from the city of Botucatu - São Paulo State - Brazil: agreement among six diagnostic criteria

    Directory of Open Access Journals (Sweden)

    Rinaldi Ana

    2010-06-01

    Full Text Available Abstract Background The metabolic syndrome has been described in children; however, a standard criterion has not been established for its diagnosis. Also, few studies have been conducted to specifically observe the possible existence of agreement among the existing diagnostic criteria. The purpose of the study is to evaluate agreement concerning prevalence rates of the metabolic syndrome diagnosed by six different criteria in overweight schoolchildren in the city of Botucatu - SP -Brazil. Methods This is a cross-sectional study on 128 overweight schoolchildren. Clinical examination included anthropometry, pubertal staging evaluation, and blood pressure. Triacylglycerol, glycemia, HDL-cholesterol, insulin levels, and HOMA-IR were determined. The Kappa index, the Mann-Whitney test and the chi-square test were used for statistical analysis. Results The prevalence of the metabolic syndrome varied from 10 to 16.5% according to different diagnostic criteria. Results were similar for boys and girls and pubertal stage. Great agreement was observed among the six different diagnostic criteria for the metabolic syndrome. Conclusions Different diagnostic criteria, when adopted for subjects with similar demographic characteristics, generate similar and compatible prevalence. Results suggest that it is possible to adopt any of the analyzed criteria, and the choice should be according to the components available for each situation.

  12. Loneliness and hypervigilance to social cues in females: an eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Gerine M A Lodder

    Full Text Available The goal of the present study was to examine whether lonely individuals differ from nonlonely individuals in their overt visual attention to social cues. Previous studies showed that loneliness was related to biased post-attentive processing of social cues (e.g., negative interpretation bias, but research on whether lonely and nonlonely individuals also show differences in an earlier information processing stage (gazing behavior is very limited. A sample of 25 lonely and 25 nonlonely students took part in an eye-tracking study consisting of four tasks. We measured gazing (duration, number of fixations and first fixation at the eyes, nose and mouth region of faces expressing emotions (Task 1, at emotion quadrants (anger, fear, happiness and neutral expression (Task 2, at quadrants with positive and negative social and nonsocial images (Task 3, and at the facial area of actors in video clips with positive and negative content (Task 4. In general, participants tended to gaze most often and longest at areas that conveyed most social information, such as the eye region of the face (T1, and social images (T3. Participants gazed most often and longest at happy faces (T2 in still images, and more often and longer at the facial area in negative than in positive video clips (T4. No differences occurred between lonely and nonlonely participants in their gazing times and frequencies, nor at first fixations at social cues in the four different tasks. Based on this study, we found no evidence that overt visual attention to social cues differs between lonely and nonlonely individuals. This implies that biases in social information processing of lonely individuals may be limited to other phases of social information processing. Alternatively, biased overt attention to social cues may only occur under specific conditions, for specific stimuli or for specific lonely individuals.

  13. A Review on Eye Movement Studies in Childhood and Adolescent Psychiatry

    Science.gov (United States)

    Rommelse, Nanda N. J.; Van der Stigchel, Stefan; Sergeant, Joseph A.

    2008-01-01

    The neural substrates of eye movement measures are largely known. Therefore, measurement of eye movements in psychiatric disorders may provide insight into the underlying neuropathology of these disorders. Visually guided saccades, antisaccades, memory guided saccades, and smooth pursuit eye movements will be reviewed in various childhood…

  14. Influence of Eye Gaze on Spoken Word Processing: An ERP Study with Infants

    Science.gov (United States)

    Parise, Eugenio; Handl, Andrea; Palumbo, Letizia; Friederici, Angela D.

    2011-01-01

    Eye gaze is an important communicative signal, both as mutual eye contact and as referential gaze to objects. To examine whether attention to speech versus nonspeech stimuli in 4- to 5-month-olds (n = 15) varies as a function of eye gaze, event-related brain potentials were used. Faces with mutual or averted gaze were presented in combination with…

  15. Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study.

    Science.gov (United States)

    Mine, Masashi; Miyata, Kimie; Morikawa, Masayuki; Nishi, Tomo; Okamoto, Nozomi; Kawasaki, Ryo; Yamashita, Hidetoshi; Kurumatani, Norio; Ogata, Nahoko

    2016-01-01

    Both visual impairment and cognitive impairment are essential factors that determine the quality of life in the aged population. The aim of this study was to determine if a correlation existed between visual acuity and cognitive impairment in an elderly Japanese population. The Fujiwara-kyo Eye Study was a cross-sectional study of individuals aged ≥68 years who lived in Nara Prefecture of Japan. Participants underwent ophthalmological examinations and cognitive function test. A mild visual impairment was defined as having a best corrected visual acuity (BCVA) >0.2 logarithm of the minimum angle of resolution (logMAR) units in the better eye. Cognitive impairment was defined as having a Mini-Mental State Examination (MMSE) score of ≤23 points. A total to 2818 individuals completed the examinations. The mean age of the participants was 76.3 ± 4.8 years (mean ± standard deviation). The mean BCVA of the better eye was -0.02 ± 0.13 logMAR units and 6.6% subjects were classified as being mildly visually impaired. The mean MMSE score was 27.3 ± 2.3 and 5.7% subjects were classified as being cognitively impaired. The proportion of subjects with cognitive or moderate visual impairment increased with age, and there was a significant correlation between the visual acuity and MMSE score (r = -0.10, p < 0.0001). Subjects with mild visual impairments had 2.4 times higher odds of having cognitive impairment than those without visual impairment (odds ratio 2.4, 95% confidence interval, 1.5-3.8, p < 0.001) after adjusting for age, sex, and length of education. We conclude that it may be important to maintain good visual acuity to reduce the risk of having cognitive impairment.

  16. Cyclosporine A Loaded PLGA Nanoparticles for Dry Eye Disease: In Vitro Characterization Studies

    Directory of Open Access Journals (Sweden)

    Vijay D. Wagh

    2014-01-01

    Full Text Available Dry eye disease is a common disease of the tear film caused by decreased tear production or increased evaporation. The objective of this study was to develop and evaluate poly (dl-lactide-co-glycolide (PLGA nanoparticles for CsA (CsA ophthalmic delivery, for the treatment of dry eye disease. Topical CsA is currently the only and safe pharmacologic treatment of severe dry eye symptoms. Nanoparticles (NPs were prepared by W/O solvent evaporation technique followed by probe sonicator and characterized for various properties such as particle size, entrapment efficiency, zeta potential, in vitro drug release, in vitro permeation studies by Franz diffusion cells, XRD, DSC, SEM, and stability studies. The developed nanosuspension showed a mean particle size in the range from 128 to 253.50 nm before freeze drying and after freeze drying 145.60 to 260.0 nm. The drug entrapment efficiency was from 58.35 to 95.69% and production yield was found between 52.29±2.4 and 85.30±2.1% in all preparations. The zeta potential of the Eudragit RL containing nanoparticles was positive, that is, 20.3 mV to 34.5 mV. The NPs formulations exhibited a biphasic drug release with initial burst followed by a very slow drug release and total cumulative release up to 24 h ranged from 69.83 to 91.92%. Kinetically, the release profiles of CsA from NPs appeared to fit best with the Higuchi model. The change of surface characteristics of NPs represents a useful approach for improvement of ocular retention and drug availability.

  17. Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study

    Science.gov (United States)

    Mine, Masashi; Miyata, Kimie; Morikawa, Masayuki; Nishi, Tomo; Okamoto, Nozomi; Kawasaki, Ryo; Yamashita, Hidetoshi; Kurumatani, Norio; Ogata, Nahoko

    2016-01-01

    Abstract Both visual impairment and cognitive impairment are essential factors that determine the quality of life in the aged population. The aim of this study was to determine if a correlation existed between visual acuity and cognitive impairment in an elderly Japanese population. The Fujiwara-kyo Eye Study was a cross-sectional study of individuals aged ≥68 years who lived in Nara Prefecture of Japan. Participants underwent ophthalmological examinations and cognitive function test. A mild visual impairment was defined as having a best corrected visual acuity (BCVA) >0.2 logarithm of the minimum angle of resolution (logMAR) units in the better eye. Cognitive impairment was defined as having a Mini-Mental State Examination (MMSE) score of ≤23 points. A total to 2818 individuals completed the examinations. The mean age of the participants was 76.3 ± 4.8 years (mean ± standard deviation). The mean BCVA of the better eye was −0.02 ± 0.13 logMAR units and 6.6% subjects were classified as being mildly visually impaired. The mean MMSE score was 27.3 ± 2.3 and 5.7% subjects were classified as being cognitively impaired. The proportion of subjects with cognitive or moderate visual impairment increased with age, and there was a significant correlation between the visual acuity and MMSE score (r = −0.10, p < 0.0001). Subjects with mild visual impairments had 2.4 times higher odds of having cognitive impairment than those without visual impairment (odds ratio 2.4, 95% confidence interval, 1.5–3.8, p < 0.001) after adjusting for age, sex, and length of education. We conclude that it may be important to maintain good visual acuity to reduce the risk of having cognitive impairment. PMID:27610269

  18. Using an eye tracker during medication administration to identify gaps in nursing students' contextual knowledge: an observational study.

    Science.gov (United States)

    Amster, Brian; Marquard, Jenna; Henneman, Elizabeth; Fisher, Donald

    2015-01-01

    In this clinical simulation study using an eye-tracking device, 40% of senior nursing students administered a contraindicated medication to a patient. Our findings suggest that the participants who did not identify the error did not know that amoxicillin is a type of penicillin. Eye-tracking devices may be valuable for determining whether nursing students are making rule- or knowledge-based errors, a distinction not easily captured via observations and interviews.

  19. The pupil is faster than the corneal reflection (CR): are video based pupil-CR eye trackers suitable for studying detailed dynamics of eye movements?

    NARCIS (Netherlands)

    Hooge, I.T.C.; Holmqvist, K.; Nyström, Marcus

    2016-01-01

    Most modern video eye trackers use the p-CR (pupil minus CR) technique to deal with small relative movements between the eye tracker camera and the eye. We question whether the p-CR technique is appropriate to investigate saccade dynamics. In two experiments we investigated the dynamics of pupil, CR

  20. Clinical features of diabetic patients with dry eye disease in a community in Maceio: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Marina Viegas Moura Rezende Ribeiro

    2016-04-01

    Full Text Available ABSTRACT Objective: This study was carried out in order to assess the epidemiological profile of symptomatic dry eye in diabetic patients. Methods: Two hundred and twenty-one diabetic patients were evaluated using a specific questionnaire about other diseases and drugs. Of these, 58 who classified as having moderate to severe dry eye were included. Results: In this study, 58 of the 221 diabetic patients had moderate to severe dry eye (26.2%. Of the 58 patients, dry eye was more prevalent at age 61.46 ± 14.18 years for men, and 61.09 ± 10.64 for women (p<0.005. Dry eye was more common in women (75.9% (p=0.456. Of the 58 patients, 15 (25.9% had at least one ocular disease.The most common was diabetic retinopathy (13 of 15 patients, 86.7%, 95% CI 69.46-103.87. A total of 19 patients used eye drops (32.8%; and most (14 of the 19 individuals, 73.7% used lubricants (95%CI 53.88-93.48. Hypertension was the most prevalent associated comorbidity (56.9% and the most commonly used medications were hypoglycemic agents (98 %, 95%CI 94.00 - 101.92 and angiotensin converting enzyme inhibitors (53.1%, 95%CI 53.06 39.09 - 67.04. Conclusion: Further epidemiologic studies need to be done to establish a real etiologic relationship between diabetes and dry eye, and its correlation to other risk factors. In spite of these limitations, we have strong evidence of this relationship, and in clinical practice, examination for dry eye should be part of the assessment of diabetic disease.

  1. [Analysis of the health and living conditions of the urban population of Botucatu, SP (Brazil). II. Knowledge and opinion of the population on symptoms of diseases].

    Science.gov (United States)

    Carandina, L; Magaldi, C

    1989-06-01

    It was verified the extent of the information of the urban population of Botucatu, SP (Brazil) on health questions. Knowledge and opinions about frequency and severity of thirteen symptoms and signs of disease were researched in 1005 families sampled. The answers were analyzed according to age, sex, level of education and socio-economic level. They showed a tendency compatible with scientific medical knowledge. In the comparison of the sexes, by age, (young adult) women gave more value to the frequency and severity of most of the symptoms than men. The high scores observed for severity showed a tendency to decrease with the increasing level of education for all the symptoms. There were variations among the symptoms in the appreciation of frequency according to the socio-economic level, with a tendency to a decrease in the high scores related to severity, according to the increase in socio-economic level. The degree of information observed in the population contradicts the prejudice, still existing in the medical area, about laymen's lack of knowledge. The hypothesis that the sample studied had access to several sources of information, among them the extensive local network of medical services, is put forward.

  2. TU-E-201-01: Methods for Eye Lens Dosimetry and Studies On Lens Opacities with Interventionists

    Energy Technology Data Exchange (ETDEWEB)

    Rehani, M. [Massachusetts General Hospital (United States)

    2015-06-15

    Madan M. Rehani, Massachusetts General Hospital and Harvard Medical School, Boston Methods for Eye Lens Dosimetry and Studies On Lens Opacities with Interventionalists Radiation induced cataract is a major threat among staff working in interventional suites. Nearly 16 million interventional procedures are performed annually in USA. Recent studies by the principal investigator’s group, primarily among interventional cardiologists, on behalf of the International Atomic Energy Agency, show posterior subcapsular (PSC) changes in the eye lens in 38–53% of main operators and 21–45% of support staff. These changes have potential to lead to cataract in future years, as per information from A-Bomb survivors. The International Commission on Radiological Protection has reduced dose limit for staff by a factor of 7.5 (from 150 mSv/y to 20 mSv/y). With increasing emphasis on radiation induced cataracts and reduction in threshold dose for eye lens, there is a need to implement strategies for estimating eye lens dose. Unfortunately eye lens dosimetry is at infancy when it comes to routine application. Various approaches are being tried namely direct measurement using active or passive dosimeters kept close to eyes, retrospective estimations and lastly correlating patient dose in interventional procedures with staff eye dose. The talk will review all approaches available and ongoing active research in this area, as well as data from surveys done in Europe on status of eye dose monitoring in interventional radiology and nuclear medicine. The talk will provide update on how good is Hp(10) against Hp(3), estimations from CTDI values, Monte Carlo based simulations and current status of eye lens dosimetry in USA and Europe. The cataract risk among patients is in CT examinations of the head. Since radiation induced cataract predominantly occurs in posterior sub-capsular (PSC) region and is thus distinguishable from age or drug related cataracts and is also preventable, actions on

  3. A new high-speed visual stimulation method for gaze-contingent eye movement and brain activity studies

    Directory of Open Access Journals (Sweden)

    Fabio eRichlan

    2013-07-01

    Full Text Available Approaches using eye movements as markers of ongoing brain activity to investigate perceptual and cognitive processes were able to implement highly sophisticated paradigms driven by eye movement recordings. Crucially, these paradigms involve display changes that have to occur during the time of saccadic blindness, when the subject is unaware of the change. Therefore, a combination of high-speed eye tracking and high-speed visual stimulation is required in these paradigms. For combined eye movement and brain activity studies (e.g., fMRI, EEG, MEG, fast and exact timing of display changes is especially important, because of the high susceptibility of these methods to visual stimulation. Eye tracking systems already achieve sampling rates up to 2000 Hz, but recent LCD technologies for computer screens reduced the temporal resolution to mostly 60 Hz, which is too slow for gaze-contingent display changes. We developed a high-speed video projection system, which is capable of reliably delivering display changes within the time frame of < 5 ms. This could not be achieved even with the fastest CRT monitors available (< 16 ms. The present video projection system facilitates the realization of cutting-edge eye movement research requiring reliable high-speed visual stimulation (e.g., gaze-contingent display changes, short-time presentation, masked priming. Moreover, this system can be used for fast visual presentation in order to assess brain activity using various methods, such as electroencephalography (EEG and functional magnetic resonance imaging (fMRI. The latter technique was previously excluded from high-speed visual stimulation, because it is not possible to operate conventional CRT monitors in the strong magnetic field of an MRI scanner. Therefore, the present video projection system offers new possibilities for studying eye movement-related brain activity using a combination of eye tracking and fMRI.

  4. The bacterial etiology of conjunctivitis in early infancy. Eye Prophylaxis Study Group.

    Science.gov (United States)

    Krohn, M A; Hillier, S L; Bell, T A; Kronmal, R A; Grayston, J T

    1993-09-01

    The authors conducted this study to determine the etiologic agents of conjunctivitis in early infancy. From 1985 to 1990, 630 infants enrolled in a randomized, controlled, double-masked study of eye prophylaxis were observed for 60 days after delivery for signs of conjunctivitis. The following isolates were categorized as pathogens: Haemophilus influenzae, Streptococcus pneumoniae, Neisseria cinerea, Klebsiella pneumoniae, and Chlamydia trachomatis. Using conditional logistic regression for analysis of 97 infant pairs, the authors identified isolates categorized as pathogens almost exclusively among cases (odds ratio (OR) = 18.0, 95% confidence interval (CI) 2.3-128). Among the microorganisms which have not usually been regarded as pathogens in the etiology of infant conjunctivitis, Streptococcus mitis was the only microorganism associated with an increased risk of conjunctivitis (OR = 5.3, 95% CI 1.8-15.0). The findings concerning the species of bacteria most often associated with conjunctivitis, as well as the finding that method of delivery is unimportant, suggest that bacteria were transmitted to the infants' eyes after birth and not from the birth canal.

  5. Cue strength in second-language processing: an eye-tracking study.

    Science.gov (United States)

    Tuninetti, Alba; Warren, Tessa; Tokowicz, Natasha

    2015-01-01

    This study used eye-tracking and grammaticality judgement measures to examine how second-language (L2) learners process syntactic violations in English. Participants were native Arabic and native Mandarin Chinese speakers studying English as an L2, and monolingual English-speaking controls. The violations involved incorrect word order and differed in two ways predicted to be important by the unified competition model [UCM; MacWhinney, B. (2005). A unified model of language acquisition. In J. F. Kroll & A. M. B. de Groot (Eds.), Handbook of bilingualism: Psycholinguistic approaches (pp. 49-67). Oxford: Oxford University Press.]. First, one violation had more and stronger cues to ungrammaticality than the other. Second, the grammaticality of these word orders varied in Arabic and Mandarin Chinese. Sensitivity to violations was relatively quick overall, across all groups. Sensitivity also was related to the number and strength of cues to ungrammaticality regardless of native language, which is consistent with the general principles of the UCM. However, there was little evidence of cross-language transfer effects in either eye movements or grammaticality judgements.

  6. Age-related changes in the macula. A histopathological study of fifty Indian donor eyes

    Directory of Open Access Journals (Sweden)

    Biswas Jyotirmay

    2002-01-01

    Full Text Available PURPOSE: Age-related macular degeneration (ARMD is clinically less common in India compared to the West. Therefore, clinicians are unfamiliar with histopathologic evidence of age-related macular changes in the Indian population. METHODS: Fifty consecutive human donor eyes removed for corneal grafting were studied for gross, microscopic and histochemical features of age-related changes in the macula in the Indian population. A horizontal block was cut from the globe including the optic disc, and the macula. Six sections, 6 microns thick, were cut from three levels in the macula at a distance of 140 microns. These were stained with haemotoxylin-eosin, periodic acid-Schiff, Mallory, Masson trichrome, alcian blue and von Kossa stains. The presence of basal laminar deposits, drusen and thickening and calcification of Bruch′s membrane in the macula were assessed at 400 x magnification using a modified version of Sark′s classification. RESULTS: Twenty-four donor eyes (48% had some form of age-related macular change. These included basal laminar deposits, hard drusen, soft drusen, extensive retinal pigment epithelium atrophy of the macula, and disciform degeneration of macula. A combination of changes was often seen. Age-related changes were more common in the seventh and eighth decade. CONCLUSION: Our study shows that histological changes characteristic of the early stages of age-related macular degeneration are fairly common in the Indian population. However, advanced macular changes are significantly rare.

  7. Eye Anatomy

    Science.gov (United States)

    ... News About Us Donate In This Section Eye Anatomy en Español email Send this article to a ... You at Risk For Glaucoma? Childhood Glaucoma Eye Anatomy Five Common Glaucoma Tests Glaucoma Facts and Stats ...

  8. Effect of cycloplegia on the refractive status of children: the Shandong children eye study.

    Directory of Open Access Journals (Sweden)

    Yuan Yuan Hu

    Full Text Available To determine the effect of 1% cyclopentolate on the refractive status of children aged 4 to 18 years.Using a random cluster sampling in a cross-sectional school-based study design, children with an age of 4-18 years were selected from kindergardens, primary schools, junior and senior high schools in a rural county and a city. Auto-refractometry was performed before and after inducing cycloplegia which was achieved by 1% cyclopentolate eye drops.Out of 6364 eligible children, data of 5999 (94.3% children were included in the statistical analysis. Mean age was 10.0±3.3 years (range: 4-18 years. Mean difference between cycloplegic and non-cycloplegic refractive error (DIFF was 0.78±0.79D (median: 0.50D; range: -1.00D to +10.75D. In univariate analysis, DIFF decreased significantly with older age (P<0.001;correlation coefficient r:-0.24, more hyperopic non-cycloplegic refractive error (P<0.001;r = 0.13 and more hyperopic cycloplegic refractive error (P<0.001;r = 0.49. In multivariate analysis, higher DIFF was associated with higher cycloplegic refractive error (P<0.001; standardized regression coefficient beta:0.50; regression coefficient B: 0.19; 95% confidence interval (CI: 0.18, 0.20, followed by lower intraocular pressure (P<0.001; beta: -0.06; B: -0.02; 95%CI: -0.03, -0.01, rural region of habitation (P = 0.001; beta: -0.04; B: -0.07; 95%CI: -0.11, -0.03, and, to a minor degree, with age (P = 0.006; beta: 0.04; B: 0.009; 95%CI: 0.003, 0.016. 66.4% of all eyes with non-cycloplegic myopia (≤-0.50D remained myopic after cycloplegia while the remaining 33.6% of eyes became emmetropic (18.0% or hyperopic (15.7% under cycloplegia. Prevalence of emmetropia decreased from 37.5% before cycloplegia to 19.8% after cycloplegia while the remaining eyes became hyperopic under cycloplegia.The error committed by using non-cycloplegic versus cycloplegic refractometry in children with mid to dark-brown iris color decreased with older age, and in parallel

  9. The association of sleep quality with dry eye disease: the Osaka study

    Directory of Open Access Journals (Sweden)

    Kawashima M

    2016-06-01

    Full Text Available Motoko Kawashima,1 Miki Uchino,1,2 Norihiko Yokoi,3 Yuichi Uchino,1,2 Murat Dogru,1 Aoi Komuro,3 Yukiko Sonomura,3 Hiroaki Kato,3 Shigeru Kinoshita,3 Kazuo Tsubota1 1Department of Ophthalmology, Keio University School of Medicine, Shinjuku-ku, 2Ryogoku Eye Clinic, Sumida-ku, Tokyo, 3Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan Purpose: To investigate the association of dry eye disease with sleep quality. Methods: In 2011, a cross-sectional survey was conducted among all the employees, mainly young and middle-aged Japanese office workers, who used visual display technology, at a company in Osaka, Japan (N=672; age range =26–64 years. The participants were classified according to the Japanese dry eye diagnosis criteria by dry eye examination results including the Schirmer test, fluorescein and lissamine green staining, tear film break-up time, and symptom questionnaire into three groups as follows: definite dry eye disease, probable dry eye disease, and no dry eye disease. To determine sleep quality, Japanese version of the Pittsburgh Sleep Quality Index (global score was implemented. The global score (range =0–21 was calculated by summing seven sleep variable scores (scale, 0–3; scores ≥5.5 indicated poor sleep. Results: The total mean global score was 5.1±2.3 (completed N=383; 45% of the dry eye disease participants reported having poor sleep quality, while 34% of the no dry eye disease participants did so, with a significant difference found in the global score (P=0.002. Furthermore, a statistically significant association was observed between the global score and dry eye disease (P=0.005. Conclusion: Poor sleep quality is associated with dry eye disease, especially with dry eye symptoms. Keywords: dry eye, sleep quality, symptom, questionnaire, Pittsburgh Sleep Quality Index, tear film break-up time, visual display terminals

  10. Feline eosinophilic keratoconjunctivitis: a retrospective study of 45 cases (56 eyes).

    Science.gov (United States)

    Dean, Eric; Meunier, Valerie

    2013-08-01

    The medical records of 45 cases (56 eyes) of feline eosinophilic keratoconjunctivitis (EKC) diagnosed between 2005 and 2011 were reviewed. Cats were included if a clinical diagnosis of EKC was recorded and eosinophils were found on corneal cytology. Median age at presentation was 5 years (interquartiles 5-9 years) for both males and females. Domestic shorthair was the predominant breed, accounting for 77.8% of the cats. The condition was unilateral in 75.6% of cases, with the superotemporal quadrant of the cornea the most frequently affected position (76.8% of eyes). A history of corneal ulceration was recorded in 37.8% of cases, and corneal ulcers were present at or before diagnosis in 66.7% of the cats. Eosinophils were found in 92.0% of conjunctival scrapings. We performed polymerase chain reaction (PCR) for feline herpesvirus type 1 (FHV-1) for 33/45 cats. Viral DNA was detected in 54.5% of these cats. FHV-1 DNA was detected by PCR in 66.7% of cats with a history and/or presence of a corneal ulcer at first presentation, which is significantly more than those with no corneal ulcer at any time (22.2% FHV-1 DNA detected). Our findings suggest that a corneal ulcer can be present prior to the development of eosinophilic keratitis. Further studies are mandatory to explore the role that FHV-1 could play in EKC-associated corneal ulceration.

  11. Exploring Text and Icon Graph Interpretation in Students with Dyslexia: An Eye-tracking Study.

    Science.gov (United States)

    Kim, Sunjung; Wiseheart, Rebecca

    2017-02-01

    A growing body of research suggests that individuals with dyslexia struggle to use graphs efficiently. Given the persistence of orthographic processing deficits in dyslexia, this study tested whether graph interpretation deficits in dyslexia are directly related to difficulties processing the orthographic components of graphs (i.e. axes and legend labels). Participants were 80 college students with and without dyslexia. Response times and eye movements were recorded as students answered comprehension questions about simple data displayed in bar graphs. Axes and legends were labelled either with words (mixed-modality graphs) or icons (orthography-free graphs). Students also answered informationally equivalent questions presented in sentences (orthography-only condition). Response times were slower in the dyslexic group only for processing sentences. However, eye tracking data revealed group differences for processing mixed-modality graphs, whereas no group differences were found for the orthography-free graphs. When processing bar graphs, students with dyslexia differ from their able reading peers only when graphs contain orthographic features. Implications for processing informational text are discussed. Copyright © 2017 John Wiley & Sons, Ltd.

  12. Does Repeated Ticking Maintain Tic Behavior? An Experimental Study of Eye Blinking in Healthy Individuals

    Directory of Open Access Journals (Sweden)

    Daniel J. V. Beetsma

    2013-01-01

    Full Text Available Tics in Tourette Syndrome (TS are often preceded by 'premonitory urges': annoying feelings or bodily sensations. We hypothesized that, by reducing annoyance of premonitory urges, tic behaviour may be reinforced. In a 2X2 experimental design in healthy participants, we studied the effects of premonitory urges (operationalized as air puffs on the eye and tic behaviour (deliberate eye blinking after a puff or a sound on changes in subjective evaluation of air puffs, and EMG responses on the m. orbicularis oculi. The experimental group with air puffs+ blinking experienced a decrease in subjective annoyance of the air puff, but habituation of the EMG response was blocked and length of EMG response increased. In the control groups (air puffs without instruction to blink, no air puffs, these effects were absent. When extrapolating to the situation in TS patients, these findings suggest that performance of tics is reinforced by reducing the subjective annoyance of premonitory urges, while simultaneously preventing habituation or even inducing sensitisation of the physiological motor response.

  13. Exploring responses to art in adolescence: a behavioral and eye-tracking study.

    Science.gov (United States)

    Savazzi, Federica; Massaro, Davide; Di Dio, Cinzia; Gallese, Vittorio; Gilli, Gabriella; Marchetti, Antonella

    2014-01-01

    Adolescence is a peculiar age mainly characterized by physical and psychological changes that may affect the perception of one's own and others' body. This perceptual peculiarity may influence the way in which bottom-up and top-down processes interact and, consequently, the perception and evaluation of art. This study is aimed at investigating, by means of the eye-tracking technique, the visual explorative behavior of adolescents while looking at paintings. Sixteen color paintings, categorized as dynamic and static, were presented to twenty adolescents; half of the images represented natural environments and half human individuals; all stimuli were displayed under aesthetic and movement judgment tasks. Participants' ratings revealed that, generally, nature images are explicitly evaluated as more appealing than human images. Eye movement data, on the other hand, showed that the human body exerts a strong power in orienting and attracting visual attention and that, in adolescence, it plays a fundamental role during aesthetic experience. In particular, adolescents seem to approach human-content images by giving priority to elements calling forth movement and action, supporting the embodiment theory of aesthetic perception.

  14. Exploring responses to art in adolescence: a behavioral and eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Federica Savazzi

    Full Text Available Adolescence is a peculiar age mainly characterized by physical and psychological changes that may affect the perception of one's own and others' body. This perceptual peculiarity may influence the way in which bottom-up and top-down processes interact and, consequently, the perception and evaluation of art. This study is aimed at investigating, by means of the eye-tracking technique, the visual explorative behavior of adolescents while looking at paintings. Sixteen color paintings, categorized as dynamic and static, were presented to twenty adolescents; half of the images represented natural environments and half human individuals; all stimuli were displayed under aesthetic and movement judgment tasks. Participants' ratings revealed that, generally, nature images are explicitly evaluated as more appealing than human images. Eye movement data, on the other hand, showed that the human body exerts a strong power in orienting and attracting visual attention and that, in adolescence, it plays a fundamental role during aesthetic experience. In particular, adolescents seem to approach human-content images by giving priority to elements calling forth movement and action, supporting the embodiment theory of aesthetic perception.

  15. Degrading traumatic memories with eye movements: a pilot functional MRI study in PTSD

    Science.gov (United States)

    Thomaes, Kathleen; Engelhard, Iris M.; Sijbrandij, Marit; Cath, Danielle C.; Van den Heuvel, Odile A.

    2016-01-01

    Background Eye movement desensitization and reprocessing (EMDR) is an effective treatment for posttraumatic stress disorder (PTSD). During EMDR, the patient recalls traumatic memories while making eye movements (EMs). Making EMs during recall is associated with decreased vividness and emotionality of traumatic memories, but the underlying mechanism has been unclear. Recent studies support a “working-memory” (WM) theory, which states that the two tasks (recall and EMs) compete for limited capacity of WM resources. However, prior research has mainly relied on self-report measures. Methods Using functional magnetic resonance imaging, we tested whether “recall with EMs,” relative to a “recall-only” control condition, was associated with reduced activity of primary visual and emotional processing brain regions, associated with vividness and emotionality respectively, and increased activity of the dorsolateral prefrontal cortex (DLPFC), associated with working memory. We used a randomized, controlled, crossover experimental design in eight adult patients with a primary diagnosis of PTSD. A script-driven imagery (SDI) procedure was used to measure responsiveness to an audio-script depicting the participant's traumatic memory before and after conditions. Results SDI activated mainly emotional processing-related brain regions (anterior insula, rostral anterior cingulate cortex (ACC), and dorsomedial prefrontal cortex), WM-related (DLPFC), and visual (association) brain regions before both conditions. Although predicted pre- to post-test decrease in amygdala activation after “recall with EMs” was not significant, SDI activated less right amygdala and rostral ACC activity after “recall with EMs” compared to post-“recall-only.” Furthermore, functional connectivity from the right amygdala to the rostral ACC was decreased after “recall with EMs” compared with after “recall-only.” Conclusions These preliminary results in a small sample suggest that

  16. OCT Study of Mechanical Properties Associated with Trabecular Meshwork and Collector Channel Motion in Human Eyes

    Science.gov (United States)

    Xin, Chen; Johnstone, Murray; Wang, Ningli; Wang, Ruikang K.

    2016-01-01

    We report the use of a high-resolution optical coherence tomography (OCT) imaging platform to identify and quantify pressure-dependent aqueous outflow system (AOS) tissue relationships and to infer mechanical stiffness through examination of tissue properties in ex vivo human eyes. Five enucleated human eyes are included in this study, with each eye prepared with four equal-sized quadrants, each encompassing 90 degrees of the limbal circumference. In radial limbal segments perfusion pressure within Schlemm’s canal (SC) is controlled by means of a perfusion cannula inserted into the canal lumen, while the other end of the cannula leads to a reservoir at a height that can control the pressure in the cannula. The OCT system images the sample with a spatial resolution of about 5 μm from the trabecular meshwork (TM) surface. Geometric parameters are quantified from the 2D OCT images acquired from the sample subjected to controlled changes in perfusion pressures; parameters include area and height of the lumen of SC, collector channel entrances (CCE) and intrascleral collector channels (ISCC). We show that 3D OCT imaging permits the identification of 3-D relationships of the SC, CCE and ISCC lumen dimensions. Collagen flaps or leaflets are found at CCE that are attached or hinged at only one end, whilst the flaps are connected to the TM by cylindrical structures spanning SC. Increasing static SC pressures resulted in SC lumen enlargement with corresponding enlargement of the CCE and ISCC lumen. Pressure-dependent SC lumen area and height changes are significant at the 0.01 levels for ANOVA, and at the 0.05 for both polynomial curves and Tukey paired comparisons. Dynamic measurements demonstrate a synchronous increase in SC, CCE and ISCC lumen height in response to pressure changes from 0 to 10, 30 or 50 mm Hg, respectively, and the response time is within the 50-millisecond range. From the measured SC volume and corresponding IOP values, we demonstrate that an

  17. The Evonik-Mainz-Eye-Care-Study (EMECS: design and execution of the screening investigation.

    Directory of Open Access Journals (Sweden)

    Lorenz Barleon

    Full Text Available To determine if screening for major ophthalmological diseases is feasible within the frame of routine occupational medicine examinations in a large working population.13037 employees of Evonik Industries aged 40 to 65 years were invited to be screened for major ophthalmological diseases (glaucoma, age related macular degeneration and diabetic retinopathy between June 2007 and March 2008 within an extended setting of occupational medicine. Ophthalmological examinations consisted of visual acuity, objective refraction, pachymetry, tonometry, perimetry (frequency doubling technology, confocal scanning laser ophthalmoscopy and digital fundus photography. Participants responded to a questionnaire addressing history of ocular and general diseases and social history.4183 participants (961 female and 3222 male were examined at 13 different sites. Response rates for eligible persons at those sites ranged from 17.9 to 60.5% but were in part limited by availability of examination slots. Average age of participants was 48.4 ± 5.4 years (mean ± SD. 4147 out of 4183 subjects (99.1% had a visual acuity ≥ 0.5 in the better eye and 3665 out of 4183 (87.6% subjects had a visual acuity ≥ 0.8 in the better eye. 1629 participants (38.9% had previously not been seen by an ophthalmologist at all or not within the last three years.This article describes the study design and basic characteristics of study participants within a large occupational medicine based screening study for ophthalmological diseases. Response rates exceeded expectations and were limiting examination capacity. Meaningful data could be obtained for almost all participants. We reached participants who previously had not received ophthalmic care. Thus, ophthalmological screening appears to be feasible within the frame of routine occupational medicine examinations.

  18. Processing Control Information in a Nominal Control Construction: An Eye-Tracking Study

    Science.gov (United States)

    Kwon, Nayoung; Sturt, Patrick

    2016-01-01

    In an eye-tracking experiment, we examined the processing of the nominal control construction. Participants' eye-movements were monitored while they read sentences that included either giver control nominals (e.g. "promise" in "Luke's promise to Sophia to photograph himself") or recipient control nominals (e.g. "plea"…

  19. Eye-tracking controlled cognitive function tests in patients with amyotrophic lateral sclerosis: a controlled proof-of-principle study.

    Science.gov (United States)

    Keller, Jürgen; Gorges, Martin; Horn, Hannah T; Aho-Özhan, Helena E A; Pinkhardt, Elmar H; Uttner, Ingo; Kassubek, Jan; Ludolph, Albert C; Lulé, Dorothée

    2015-08-01

    Amyotrophic lateral sclerosis (ALS) primarily affects motor and speech abilities. In addition, cognitive functions are impaired in a subset of patients. There is a need to establish an eye movement-based method of neuropsychological assessment suitable for severely physically impaired patients with ALS. Forty-eight ALS patients and thirty-two healthy controls matched for age, sex and education performed a hand and speech motor-free version of the Raven's coloured progressive matrices (CPM) and the D2-test which had been especially adapted for eye-tracking control. Data were compared to a classical motor-dependent paper-pencil version. The association of parameters of the eye-tracking and the paper-pencil version of the tests and the differences between and within groups were studied. Subjects presented similar results in the eye-tracking and the corresponding paper-pencil versions of the CPM and D2-test: a correlation between performance accuracy for the CPM was observed for ALS patients (p < 0.001) and controls (p < 0.001) and in the D2-test for controls (p = 0.048), whereas this correlation did not reach statistical significance for ALS patients (p = 0.096). ALS patients performed worse in the CPM than controls in the eye-tracking (p = 0.053) and the paper-pencil version (p = 0.042). Most importantly, eye-tracking versions of the CPM (p < 0.001) and the D2-test (p = 0.024) reliably distinguished between more and less cognitively impaired patients. Eye-tracking-based neuropsychological testing is a promising approach for assessing cognitive deficits in patients who are unable to speak or write such as patients with severe ALS.

  20. Obstacle avoidance, visual detection performance, and eye-scanning behavior of glaucoma patients in a driving simulator: a preliminary study.

    Directory of Open Access Journals (Sweden)

    Rocío Prado Vega

    Full Text Available The objective of this study was to evaluate differences in driving performance, visual detection performance, and eye-scanning behavior between glaucoma patients and control participants without glaucoma. Glaucoma patients (n = 23 and control participants (n = 12 completed four 5-min driving sessions in a simulator. The participants were instructed to maintain the car in the right lane of a two-lane highway while their speed was automatically maintained at 100 km/h. Additional tasks per session were: Session 1: none, Session 2: verbalization of projected letters, Session 3: avoidance of static obstacles, and Session 4: combined letter verbalization and avoidance of static obstacles. Eye-scanning behavior was recorded with an eye-tracker. Results showed no statistically significant differences between patients and control participants for lane keeping, obstacle avoidance, and eye-scanning behavior. Steering activity, number of missed letters, and letter reaction time were significantly higher for glaucoma patients than for control participants. In conclusion, glaucoma patients were able to avoid objects and maintain a nominal lane keeping performance, but applied more steering input than control participants, and were more likely than control participants to miss peripherally projected stimuli. The eye-tracking results suggest that glaucoma patients did not use extra visual search to compensate for their visual field loss. Limitations of the study, such as small sample size, are discussed.

  1. Processing rhythmic pattern during Chinese sentence reading: An eye movement study

    Directory of Open Access Journals (Sweden)

    Yingyi eLuo

    2015-12-01

    Full Text Available Prosodic constraints play a fundamental role during both spoken sentence comprehension and silent reading. In Chinese, the rhythmic pattern of the verb-object (V-O combination has been found to rapidly affect the semantic access/integration process during sentence reading (Luo and Zhou, 2010. Rhythmic pattern refers to the combination of words with different syllabic lengths, with certain combinations disallowed (e.g., [2+1]; numbers standing for the number of syllables of the verb and the noun respectively and certain combinations preferred (e.g., [1+1] or [2+2]. This constraint extends to the situation in which the combination is used to modify other words. A V-O phrase could modify a noun by simply preceding it, forming a V-O-N compound; when the verb is disyllabic, however, the word order has to be O-V-N and the object is preferred to be disyllabic. In this study, we investigated how the reader processes the rhythmic pattern and word order information by recording the reader’s eye-movements. We created four types of sentences by crossing rhythmic pattern and word order in compounding. The compound, embedding a disyllabic verb, could be in the correct O-V-N or the incorrect V-O-N order; the object could be disyllabic or monosyllabic. We found that the reader spent more time and made more regressions on and after the compounds when either type of anomaly was detected during the first pass reading. However, during re-reading (after all the words in the sentence have been viewed, less regressive eye movements were found for the anomalous rhythmic pattern, relative to the correct pattern; moreover, only the abnormal rhythmic pattern, not the violated word order, influenced the regressive eye movements. These results suggest that while the processing of rhythmic pattern and word order information occurs rapidly during the initial reading of the sentence, the process of recovering from the rhythmic pattern anomaly may ease the reanalysis

  2. Prevalence of dry eye syndrome at patients with diabetus melitus tip 2, one year retrospective study May 2011-June 2012

    Institute of Scientific and Technical Information of China (English)

    Nora Burda; Vilma Mema; Ejup Mahmudi Md; Brikena Selimi; Sulejman Zhugli; Basri Lenajni; Illaz Bunjaku

    2012-01-01

    Objective: To prescribe and analyze the correlation of Dry Eye and Diabetes Mellitus Tip II, at Polyclinic of Specialties Nr. 2 Ophthalmology service, between May 2011 and June 2012.Methods:A total number of 223 patients diagnosed with Diabetes Mellitus Tip II underwent ocular examinations. 120 male and 103 female, aged from 24-73 years old. To confirm the presence of diabetes among these patients fasting blood glucose level was performed (normal limit < 110 mg/dL). History of disease, duration of diabetes, age, sex was obtained by reviewing the medical records and direct patient interview. Also the patients complains: tearing photophobia, red eye, itching ,foreign body sensation, blurred vision was recorded. From the study were excluded all conditions which affects the tear film stability and contact lens wearer.Results: 118 patients were diagnosed with Dry Eye Syndrome of varying degrees. 58 male/61 female. The diagnosis was made by heaving two or more positive tests performed as mentioned above, and referring to patients complains. Fourteen patients represent pinpoint corneal dye with fluorosceini, forty-six patients was positive to cotton swab test diminution of corneal sensitivity, eighty-nine patients was positive to Schirmmer test less than 10 mm, positive TBUT test less than 9 s was found to be the amount of seventy-one patients. Positive tear meniscus at inferior lid margin was found at fifty-six patients. Dry eye is a disorder of tear film because of tear deficiency or excessive tear evaporation which causes damage to the inter palpaberal ocular surface and is associated with symptoms of ocular discomfort. This ocular disorder is very common among general population with 28% of the adults having dry eye syndrome. Early diagnosis and timely treatment, complications as secondary microbial infection and corneal ulceration could be avoided. Conclusions: In our study the Dry Eye Syndrome showed to have a high correlation with Diabetes Mellitus Tip II (about 52

  3. Accessibility of Referent Information Influences Sentence Planning: An Eye-Tracking Study

    Science.gov (United States)

    Ganushchak, Lesya Y.; Konopka, Agnieszka E.; Chen, Yiya

    2017-01-01

    This study investigated the time-course of online sentence formulation (i.e., incrementality in sentence planning) as a function of the preceding discourse context. In two eye-tracking experiments, participants described pictures of transitive events (e.g., a frog catching a fly). The accessibility of the agent (Experiment 1) and patient (Experiment 2) was manipulated in the discourse preceding each picture. In the Literal condition, participants heard a story where the agent or patient was mentioned explicitly (fly, frog). In the Associative condition, the agent or patient was not mentioned but was primed by the story (via semantically or associatively related words such as insect, small, black, wings). In the No Mention condition, the stories did not explicitly mention or prime either character. The target response was expected to have the same structure and content in all conditions (SVO sentences: The frog catches the fly). The results showed that participants generally looked first at the agent, before speech onset, regardless of condition, and then at the patient around and after speech onset. Analyses of eye movements in time window associated with linguistic planning showed that formulation was sensitive mainly to whether the agent was literally mentioned in the context or not and to lesser extent to conceptual accessibility (Experiment 1). Furthermore, accessibility of the patient (be it literal mention of its name or only availability of the concept) showed no effect on the time-course of utterance planning (Experiment 2). Together, these results suggest that linguistic planning before speech onset was influenced only by the accessibility of the first character name in the sentence, providing further evidence for highly incremental planning in sentence production. PMID:28293201

  4. Psoriasis: an eye opener – a cross-sectional study in a Tertiary Care Hospital of South India

    Directory of Open Access Journals (Sweden)

    Hari Kishan Kumar Yadalla

    2015-01-01

    Full Text Available Introduction: Psoriasis is a multi-system chronic inflammatory skin disease targeting 2% to 3% of the general population. It is a prototype of immune dysregulation mediated by TH1 proinflammatory cytokines such as TNF-α, IFN-gamma, IL-6, and IL-12 with far reaching systemic effects. There is growing and emerging evidence that psoriasis patients have a higher prevalence of associated comorbid diseases, with severe skin disease portends a serious risk for development of these comorbidities and are found to have a higher association of extracutaneous disease manifestations. Aim: To look for eye involvement in psoriasis patients and to evaluate the risk and prognostic factors of disease association. Material and Methods: 200 Patients with psoriasis were screened for any eye involvement after few unusual case presentations with eye complications during the period from September 2013 - August 2014. Results: First case was a post cataract sudden loss of vision secondary to development of uveitis in a female patient aged 52 years, with past history of psoriasis with minimal skin lesions and no arthritis. Another 5 cases of psoriasis with eye involvement were detected during the screening employed in a series of 200 psoriasis cases. Conclusion: The present report highlights the importance of psoriasis and eye involvement, need for collaboration between dermatologists and ophthalmologists for thorough examination and evaluation prior to any surgical intervention and also further long term follow-up studies are warranted for confirmation of this causal relationship.

  5. [N-acetyl-aspartylglutamic acid eye drops in allergic-type conjuctivitis. Double-blind comparative clinical study].

    Science.gov (United States)

    Bonnet, M; Ducournau, D; Lumbroso, P; Serpin, G

    1985-01-01

    Fifty patients with allergic conjunctivitis were included in a double-blind randomized clinical trial designed to compare the efficiency and tolerance of two antiallergic eye-drops: one containing NAAGA (22 patients), the other one containing disodium Cromoglycate (28 patients). Both treatments were used at a dosage of 1 drop 4 times per day. Ocular symptoms, conjunctivo-corneal signs and the subjective ocular condition assessed by the patients themselves with visual analogue scales, were all significantly improved by both eye-drops during the first month of treatment. Statistical analysis showed that patient ocular condition improved more rapidly with NAAGA eye-drops. In 25 patients (12 in the NAAGA group and 13 in the Cromoglycate group), the study was continued for an additional month according to a cross-over protocol. During the 2nd month of treatment, additional improvement of ocular symptoms and signs were observed with both eye-drops but more markedly in those patients who received NAAGA after Cromoglycate. Ocular tolerance was good for both eye-drops.

  6. Eye-Tracking

    Directory of Open Access Journals (Sweden)

    Gabriela GROSSECK

    2006-01-01

    Full Text Available Eye-tracking: one of the newest and most efficient methods of improving on-line marketing communication is called eye-tracking. Marketers have borrowed this technique, usually used in psychological and medical research, in order to study web users with the help of a video camera incorporated in the monitor.

  7. Small Drusen and Age-Related Macular Degeneration: The Beaver Dam Eye Study

    Directory of Open Access Journals (Sweden)

    Ronald Klein

    2015-03-01

    Full Text Available We tested the hypothesis that large areas of small hard drusen (diameter <63 µm and intermediate drusen (diameter 63–124 µm are associated with the incidence of age-related macular degeneration (AMD. Eyes of 3344 older adults with at least two consecutive visits spaced five years apart over a 20-year period were included. A 6-level severity scale, including no drusen, four levels of increasing area (from minimal (<2596 µm² to large (>9086 µm² of only small hard drusen, and intermediate drusen, was used. The five-year incidence of AMD was 3% in eyes at the start of the interval with no, minimal, small, and moderate areas of only small drusen and 5% and 25% for eyes with large area of only small drusen and intermediate drusen, respectively. Compared to eyes with a moderate area of small drusen, the odds ratio (OR of developing AMD in eyes with a large area of only small drusen was 1.8 (p < 0.001. Compared to eyes with large area of only small drusen, eyes with intermediate drusen had an OR of 5.5 (p < 0.001 of developing AMD. Our results are consistent with our hypothesis that large areas of only small drusen are associated with the incidence of AMD.

  8. The Effect of Word-Unit Spacing upon the Reading Strategies of Non-Native Readers of Chinese: An Eye-Tracking Study.

    Science.gov (United States)

    1986-01-01

    ELECTE FEB ID THE EFFECT OF WORD-UNIT SPACING UPON THE READING STRATEGIES OF NATIVE AND NON-NATIVE READERS OF CHINESE: AN EYE - TRACKING STUDY DISSERTATION...Effect of Word-Unit Spacing Upon the Reading IAMs/DISSERTATION Strategies of Native and Non-Native Readers of Chinese: An Eye - Tracking Study 6...interest in the reading process, and made sure that any technical problems experienced with the eye tracking equipment were quickly remedied. My

  9. The Australian Space Eye: studying the history of galaxy formation with a CubeSat

    Science.gov (United States)

    Horton, Anthony; Spitler, Lee; Mathers, Naomi; Petkovic, Michael; Griffin, Douglas; Barraclough, Simon; Benson, Craig; Dimitrijevic, Igor; Lambert, Andrew; Previte, Anthony; Bowen, John; Westerman, Solomon; Puig-Suari, Jordi; Reisenfeld, Sam; Lawrence, Jon; Zhelem, Ross; Colless, Matthew; Boyce, Russell

    2016-07-01

    The Australian Space Eye is a proposed astronomical telescope based on a 6U CubeSat platform. The Space Eye will exploit the low level of systematic errors achievable with a small space based telescope to enable high accuracy measurements of the optical extragalactic background light and low surface brightness emission around nearby galaxies. This project is also a demonstrator for several technologies with general applicability to astronomical observations from nanosatellites. Space Eye is based around a 90 mm aperture clear aperture all refractive telescope for broadband wide field imaging in the i' and z' bands.

  10. The Australian Space Eye: studying the history of galaxy formation with a CubeSat

    CERN Document Server

    Horton, Anthony; Mathers, Naomi; Pektovic, Michael; Griffin, Douglas; Barraclough, Simon; Benson, Craig; Dimitrijevic, Igor; Lambert, Andrew; Previte, Anthony; Bowen, John; Westerman, Solomon; Puig-Suari, Jordi; Reisenfeld, Sam; Lawrence, Jon; Zhelem, Ross; Colless, Matthew; Boyce, Russell

    2016-01-01

    The Australian Space Eye is a proposed astronomical telescope based on a 6U CubeSat platform. The Space Eye will exploit the low level of systematic errors achievable with a small space based telescope to enable high accuracy measurements of the optical extragalactic background light and low surface brightness emission around nearby galaxies. This project is also a demonstrator for several technologies with general applicability to astronomical observations from nanosatellites. Space Eye is based around a 90 mm aperture clear aperture all refractive telescope for broadband wide field imaging in the i and z bands.

  11. Diabetes eye exams

    Science.gov (United States)

    Diabetic retinopathy - eye exams; Diabetes - eye exams; Glaucoma - diabetic eye exam; Macular edema - diabetic eye exam ... if the doctor who takes care of your diabetes checks your eyes, you need an eye exam ...

  12. Facts About Pink Eye

    Science.gov (United States)

    ... Eye (Conjunctivitis) > Facts About Pink Eye Facts About Pink Eye Pink eye is one of the most ... treatment depends on the underlying cause. What is pink eye? Pink eye, also known as conjunctivitis, involves ...

  13. Dilating Eye Drops

    Science.gov (United States)

    ... Corneal Abrasions Dilating Eye Drops Lazy eye (defined) Pink eye (defined) Retinopathy of Prematurity Strabismus Stye (defined) Vision ... Corneal Abrasions Dilating Eye Drops Lazy eye (defined) Pink eye (defined) Retinopathy of Prematurity Strabismus Stye (defined) Vision ...

  14. Eye-gaze patterns as students study worked-out examples in mechanics

    Directory of Open Access Journals (Sweden)

    Brian H. Ross

    2010-10-01

    Full Text Available This study explores what introductory physics students actually look at when studying worked-out examples. Our classroom experiences indicate that introductory physics students neither discuss nor refer to the conceptual information contained in the text of worked-out examples. This study is an effort to determine to what extent students incorporate the textual information into the way they study. Student eye-gaze patterns were recorded as they studied the examples to aid them in solving a target problem. Contrary to our expectations from classroom interactions, students spent 40±3% of their gaze time reading the textual information. Their gaze patterns were also characterized by numerous jumps between corresponding mathematical and textual information, implying that they were combining information from both sources. Despite this large fraction of time spent reading the text, student recall of the conceptual information contained therein remained very poor. We also found that having a particular problem in mind had no significant effects on the gaze-patterns or conceptual information retention.

  15. Prevalencia de Demodex folliculorum e Demodex brevis em uma amostra da população de Botucatu, São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    N.G. Madeira

    1993-12-01

    Full Text Available Pela primeira vez no Brasil foi realizado um levantamento para se conhecer a distribuição do D. folliculorum e D. brevis no homem. Uma amostra de 100 pessoas atendida em clínica estética foi examinada, procurando-se estudar a associação entre a presença de ácaros e fatores como idade, raça e sexo do hospedeiro. O material colhido da região facial dos indivíduos foi montado em lâminas com o meio de Berlese. Das 100 pessoas examinadas, 72 % foram positivas. Dos casos positivos, 51 % estavam infestados pelo D. folliculorum, 2% pelo D. brevis e 19% apresentaram-se parasitados por ambas as espécies.A survey was conduced to determine the prevalence of D. folliculorum and D. brevis for the first time in Brazil. In this study, association between the presence of mites and hostfactors (age, sex and race were anatysed. Samples were obtained from 100 individuals submitted to a facial cleaning in an aesthetic clinic in Botucatu city. All the samples were mounted in Berleses medium and examined by dark-field phase microscopy. From 100 studied individuais, 72 were positive, among the positive cases, 51% showed D. folliculorum, 2% showed D. brevis and 19% both species. The parasite distribution in realtion to sex was not taken in account because the sex ratio tavoured females (90%. According to age, prevalence was high in all age groups. The factors influencing this distribution could be due. 1. the examination of extensive skin areas, 2. the group examined composed of individuals in treatment in an anaesthetic clinic could be more infested than a normal population, 3. the fact that in tropics, the prevalence is often high in all ages.

  16. The Effectiveness of Panoramic Maps Design: a Preliminary Study Based on Mobile Eye-Tracking

    Science.gov (United States)

    Balzarini, R.; Murat, M.

    2016-06-01

    This paper presents preliminary results from an ongoing research based on the study of visual attention through mobile eye-tracking techniques. The visual-cognitive approach investigates the reading-comprehension of a particular territorial representation: ski trails maps. The general issue of the study is to provide insights about the effectiveness of panoramic ski maps and more broadly, to suggest innovative efficient representation of the geographic information in mountain. According to some mountain operators, the information provided by paper ski maps no longer meets the needs of a large part of the customers; the question now arises of their adaptation to new digital practices (iPhone, tablets). In a computerized process perspective, this study particularly focuses on the representations, and the inferred information, which are really helpful to the users-skiers to apprehend the territory and make decisions, and which could be effectively replicated into a digital system. The most interesting output relies on the relevance of the panorama view: panorama still fascinates, but contrary to conventional wisdom, the information it provides does not seem to be useful to the skier. From a socio-historical perspective this study shows how empirical evidence-based approach can support the change: our results enhance the discussion on the effectiveness of the message that mountain operators want to convey to the tourist and therefore, on the renewal of (geographical) information in ski resorts.

  17. THE EFFECTIVENESS OF PANORAMIC MAPS DESIGN: A PRELIMINARY STUDY BASED ON MOBILE EYE-TRACKING

    Directory of Open Access Journals (Sweden)

    R. Balzarini

    2016-06-01

    Full Text Available This paper presents preliminary results from an ongoing research based on the study of visual attention through mobile eye-tracking techniques. The visual-cognitive approach investigates the reading-comprehension of a particular territorial representation: ski trails maps. The general issue of the study is to provide insights about the effectiveness of panoramic ski maps and more broadly, to suggest innovative efficient representation of the geographic information in mountain. According to some mountain operators, the information provided by paper ski maps no longer meets the needs of a large part of the customers; the question now arises of their adaptation to new digital practices (iPhone, tablets. In a computerized process perspective, this study particularly focuses on the representations, and the inferred information, which are really helpful to the users-skiers to apprehend the territory and make decisions, and which could be effectively replicated into a digital system. The most interesting output relies on the relevance of the panorama view: panorama still fascinates, but contrary to conventional wisdom, the information it provides does not seem to be useful to the skier. From a socio-historical perspective this study shows how empirical evidence-based approach can support the change: our results enhance the discussion on the effectiveness of the message that mountain operators want to convey to the tourist and therefore, on the renewal of (geographical information in ski resorts.

  18. A Preliminary Study of Automatic Delineation of Eyes on CT Images Using Ant Colony Optimization

    Institute of Scientific and Technical Information of China (English)

    LI Yong-jie; XIE Wei-fu; YAO De-zhong

    2007-01-01

    Eyes are important organs-at-risk (OARs) that should be protected during the radiation treatment of those head tumors. Correct delineation of the eyes on CT images is one of important issues for treatment planning to protect the eyes as much as possible. In this paper, we propose a new method, named ant colony optimization (ACO), to delineate the eyes automatically.In the proposed algorithm, each ant tries to find a closed path, and some pheromone is deposited on the visited path when the ant finds a path. After all ants finish a circle, the best ant will lay some pheromone to enforce the best path. The proposed algorithm is verified on several CT images, and the preliminary results demonstrate the feasibility of ACO for the delineation problem.

  19. Eyes - bulging

    Science.gov (United States)

    ... emotional support is important. When to Contact a Medical Professional Call your health care provider if: You have bulging eyes and the cause has not yet been diagnosed. Bulging eyes are accompanied by other symptoms. ... The provider will ask about your medical history and do a physical exam. Some questions ...

  20. Your Eyes

    Science.gov (United States)

    ... eyes to see millions of colors. Helping You See It All Rods and cones process the light to give you the total picture. You're ... get cloudy, causing a cataract . A cataract prevents light from reaching the retina and makes it difficult to see. The eyes you have will be yours forever — ...

  1. Sensitivity to Speaker Control in the Online Comprehension of Conditional Tips and Promises: An Eye-Tracking Study

    Science.gov (United States)

    Stewart, Andrew J.; Haigh, Matthew; Ferguson, Heather J.

    2013-01-01

    Statements of the form if… then… can be used to communicate conditional speech acts such as tips and promises. Conditional promises require the speaker to have perceived control over the outcome event, whereas conditional tips do not. In an eye-tracking study, we examined whether readers are sensitive to information about perceived speaker control…

  2. Obstacle avoidance, visual detection performance, and eye-scanning behavior of glaucoma patients in a driving simulator: a preliminary study

    NARCIS (Netherlands)

    Prado Vega, R.; Van Leeuwen, P.M.; Rendon Velez, E.; Lemij, H.G.; De Winter, J.C.

    2013-01-01

    The objective of this study was to evaluate differences in driving performance, visual detection performance, and eye-scanning behavior between glaucoma patients and control participants without glaucoma. Glaucoma patients (n = 23) and control participants (n = 12) completed four 5-min driving sessi

  3. Estimation of Flavonoid Intake in Older Australians: Secondary Data Analysis of the Blue Mountains Eye Study.

    Science.gov (United States)

    Kent, Katherine; Charlton, Karen E; Russell, Joanna; Mitchell, Paul; Flood, Victoria M

    2015-01-01

    Flavonoids, consumed in plant-based foods, have been linked to risk reduction of cancers, cardiovascular, and neurodegenerative diseases. The paucity of information on dietary sources and quantities of flavonoid intake in older adults limits interpretation of epidemiological studies that link flavonoid intake with health outcomes in this population. It was our aim to describe total flavonoid intake, including flavonoid subclasses, in older Australians and to identify rich and commonly consumed sources of flavonoids in this age group. Twelve days of weighed food record dietary data from a subsample of the Blue Mountains Eye Study baseline cohort study of older Australians (n = 79) was analyzed using the US Department of Agriculture flavonoid database. Mean intake of flavonoids was estimated to be 683 mg/day (SD = 507) of which flavan-3-ols contributed 92%, followed by flavonols (4%), flavanones (3%), and flavones (<1%). Black tea was the major flavonoid source, providing 89% of total flavonoid intake. No differences in intake between genders were identified. Dietary intake of flavonoids and flavonoid subclasses in older Australians is similar to the one other estimation of intake in Australian older adults and confirms the types of foods that contribute to flavonoid intake among this sample of older Australians.

  4. Inflammation in dry eye associated with rheumatoid arthritis: cytokine and in vivo confocal microscopy study.

    Science.gov (United States)

    Villani, Edoardo; Galimberti, Daniela; Del Papa, Nicoletta; Nucci, Paolo; Ratiglia, Roberto

    2013-01-01

    The purpose of this research was to study ocular surface inflammation in relation to systemic disease activity in rheumatoid arthritis (RA) patients with or without secondary Sjögren's syndrome (SSII and non-SSII respectively). The study was conducted in two phases. In phase I, 12 patients with active RA SSII and 12 with active RA non-SSII were consecutively enrolled. Each completed an Ocular Surface Disease Index (OSDI) questionnaire and underwent a full eye exam and in vivo confocal microscopy examination of the cornea. Tear fluid samples were collected in sponges and analyzed for IL-1α, -6, and -8, and TNF-α. When RA activity was suppressed by systemic treatment the patients entered phase II of the study in which all of the phase I examinations were repeated. In RA SSII patients, OSDI, fluorescein staining dendritic cell density, and concentrations of IL-1α and IL-6 decreased significantly (P < 0.01) between phases I and II. Tear breakup time scores increased significantly. For RA non-SSII patients, there were no significant differences between phases I and II. Differences in the clinical, cellular and cytokine responsiveness to systemic RA treatments show that the ocular surface pathology is dissimilar for RA SSII and RA non-SSII patients.

  5. Eye-movement study during visual search in Chinese children with developmental dyslexia

    Institute of Scientific and Technical Information of China (English)

    LI Xiu-hong; JING Jin; YANG De-sheng; WANG Hui; WANG Qing-xiong; SONG Shan-shan; FAN Fang

    2013-01-01

    Background Developmental dyslexia (DD) is a disorder in which children with normal intelligence and sensory abilities show learning deficits in reading.Abnormal eye movements have been found in DD.However,eye-movement abnormalities during visual search among Chinese children with DD remain unknown.We aimed to identify the eyemovement characteristics and search efficiency of Chinese children with DD during visual search for targets of different conceptual categories,under same-category conditions.Methods We compared 32 Chinese dyslexic children and 39 non-dyslexic children in visual search tasks,which were assessed using EyeLink Ⅱ High-Speed Eye Tracker (SR Research Ltd.,Canada).Letters,single Chinese characters,digits,Chinese phrases,figures and facial expressions were used as stimuli.Targets were similar to distractors in meaning,phonology and/or shape.Results A main effect of task on visual search scores and all eye-movement parameters were found.Search scores,average saccade amplitude and saccade distance were significantly smaller in the DD group than in the controls.An interaction between group and task was found for pupil diameter.Conclusions Unlike normal readers,children with DD had a reduction in the visual attention span and search accuracy.Besides,children with DD could not increase their mental workload with increase in task difficulty.The conceptual category of the stimulus materials significantly impacts search speed,accuracy and eye-movement parameters.

  6. Our experience with Solcoseryl Eye-Gel in the treatment of corneal lesions. A randomised double-blind study (with 1 color plate).

    Science.gov (United States)

    Erbe, W; Herrmann, R; Körner, W F; Rohde-Germann, H; Straub, W

    1984-01-01

    A comparative study of Solcoseryl Eye-Gel versus a 2.4% cysteine eye-gel was carried out under controlled conditions (randomised and double-blind) on a total of 61 patients with corneal lesions (52 foreign body injuries, 9 corneal erosions). The results showed a marked superiority of Solcoseryl Eye-Gel with respect to more rapid healing and also with respect to the possible subsequent development of a corneal macula.

  7. Epidemilogic survey of dermatophytosis in dogs and cats attended at the dermatology service of the College of Veterinary Medicine and Animal Science of UNESP - Botucatu /

    Directory of Open Access Journals (Sweden)

    Rodrigo Gracia Motta

    2010-07-01

    Full Text Available The objective of this study was to assess the medical records of the patients whose mycological culture of the hair in Sabouraud Dextrose Agar supplemented with chloramphenicol and cycloheximide was positive for dermathophytes, and review the cases of dermatophytosis. One hundred and thirty six medical records of patients (114 dogs and 22 cats with dermatophytosis attended in a period of 54 months in the Veterinary Hospital of the UNESP – Botucatu were evaluated. Results obtained in this analysis have shown that the majority of the cultures were positive for Mycrosporum canis. There was no statistical difference between genders, but the number of defined breed dogs presenting dermatophytosis was higher than mongrel dogs. Among feline cases, however, there were a higher number of mongrel cats. The majority of the people and animals in contact with the patients did not report skin lesions. 32,5% 0f the dogs presented middle intensity itchiness, while in cats itchiness was absent in 77,3% of cases. 69,3% of the animals did not present clinical signs other than dermatological. Mean ages were 4 years in dogs and 3 years in cats. There was no statistical effect of season in the occurrence of dermatophytosis. Among animals submitted to Wood lamp evaluation, 40,9% of the dogs and 33,3% of the cats were positive for dermatophytes. Most dogs had generalized lesions, while the majority of cats presented focal lesions. The most common lesions observed were: alopecia, crusts and erythema.O objetivo do presente trabalho foi avaliar os prontuários dos pacientes cuja cultura micológica do pêlo, em meio Ágar Sabouraud dextrose, suplementado com cloranfenicol e ciclohexamida, foi positiva para dermatófitos, e realizar um levantamento da casuística de dermatofitose. Foram avaliados 136 prontuários de pacientes (114 caninos e 22 felinos com dermatofitose atendidos em período de 54 meses, no Hospital Veterinário da UNESP de Botucatu. Pela análise dos

  8. A Monte Carlo study on the effect of the orbital bone to the radiation dose delivered to the eye lens

    Science.gov (United States)

    Stratis, Andreas; Zhang, Guozhi; Jacobs, Reinhilde; Bogaerts, Ria; Bosmans, Hilde

    2015-03-01

    The aim of this work was to investigate the influence of backscatter radiation from the orbital bone and the intraorbital fat on the eye lens dose in the dental CBCT energy range. To this end we conducted three different yet interrelated studies; A preliminary simulation study was conducted to examine the impact of a bony layer situated underneath a soft tissue layer on the amount of backscatter radiation. We compared the Percentage Depth Dose (PDD) curves in soft tissue with and without the bone layer and we estimated the depth in tissue where the decrease in backscatter caused by the presence of the bone is noticeable. In a supplementary study, an eye voxel phantom was designed with the DOSxyznrc code. Simulations were performed exposing the phantom at different x-ray energies sequentially in air, in fat tissue and in realistic anatomy with the incident beam perpendicular to the phantom. Finally, a virtual head phantom was implemented into a validated hybrid Monte Carlo (MC) framework to simulate a large Field of View protocol of a real CBCT scanner and examine the influence of scattered dose to the eye lens during the whole rotation of the paired tube-detector system. The results indicated an increase in the dose to the lens due to the fatty tissue in the surrounding anatomy. There is a noticeable dose reduction close to the bone-tissue interface which weakens with increasing distance from the interface, such that the impact of the orbital bone in the eye lens dose becomes small.

  9. Knowledge and attitude for eye diseases and satisfaction for services among urban citizens of Oman: A pilot study

    Directory of Open Access Journals (Sweden)

    Rajiv Khandekar

    2008-01-01

    Materials and Methods: This was a descriptive study. 156 Omani citizens of more than 12 years of age were given a close ended questionnaire. Their self reported responses were collected. Six questions related to cataract, diabetic retinopathy, refractive error, blindness, home treatment, rehabilitation of visually impaired and perception of eye services at Ministry of Health hospitals were asked with three grades of responses to choose from. Results: The knowledge about cataract and diabetic retinopathy was found to be good in more than 70% of respondents. 35% of participants agreed for home treatment of minor eye ailments. The importance of using visual aids and the need to give special facilities for the visually impaired was positive in 85%. Two thirds of the respondents were satisfied with type of eye services. Association of knowledge and satisfaction to the gender and age group was not conclusive. Conclusions: Knowledge regarding cataract surgery and blindness due to diabetes, attitude towards use of spectacles, perceived need for visual rehabilitation and satisfaction with eye care services was positive in more than 60% of the interviewed people in this pilot study. A larger study representing Omani population is recommended.

  10. Rapid eye movement-sleep is reduced in patients with acute uncomplicated diverticulitis—an observational study

    Directory of Open Access Journals (Sweden)

    Chenxi Huang

    2015-08-01

    Full Text Available Introduction. Sleep disturbances are commonly found in patients in the postoperative period. Sleep disturbances may give rise to several complications including cardiopulmonary instability, transient cognitive dysfunction and prolonged convalescence. Many factors including host inflammatory responses are believed to cause postoperative sleep disturbances, as inflammatory responses can alter sleep architecture through cytokine-brain interactions. Our aim was to investigate alteration of sleep architecture during acute infection and its relationships to inflammation and clinical symptoms.Materials & Methods. In this observational study, we included patients with acute uncomplicated diverticulitis as a model to investigate the isolated effects of inflammatory responses on sleep. Eleven patients completed the study. Patients were admitted and treated with antibiotics for two nights, during which study endpoints were measured by polysomnography recordings, self-reported discomfort scores and blood samples of cytokines. One month later, the patients, who now were in complete remission, were readmitted and the endpoints were re-measured (the baseline values.Results. Total sleep time was reduced 4% and 7% the first (p = 0.006 and second (p = 0.014 nights of diverticulitis, compared to baseline, respectively. The rapid eye movement sleep was reduced 33% the first night (p = 0.016, compared to baseline. Moreover, plasma IL-6 levels were correlated to non-rapid eye movement sleep, rapid eye movement sleep and fatigue.Conclusion. Total sleep time and rapid eye movement sleep were reduced during nights with active diverticulitis and correlated with markers of inflammation.

  11. Degrading traumatic memories with eye movements: a pilot functional MRI study in PTSD

    Directory of Open Access Journals (Sweden)

    Kathleen Thomaes

    2016-11-01

    Full Text Available Background: Eye movement desensitization and reprocessing (EMDR is an effective treatment for posttraumatic stress disorder (PTSD. During EMDR, the patient recalls traumatic memories while making eye movements (EMs. Making EMs during recall is associated with decreased vividness and emotionality of traumatic memories, but the underlying mechanism has been unclear. Recent studies support a “working-memory” (WM theory, which states that the two tasks (recall and EMs compete for limited capacity of WM resources. However, prior research has mainly relied on self-report measures. Methods: Using functional magnetic resonance imaging, we tested whether “recall with EMs,” relative to a “recall-only” control condition, was associated with reduced activity of primary visual and emotional processing brain regions, associated with vividness and emotionality respectively, and increased activity of the dorsolateral prefrontal cortex (DLPFC, associated with working memory. We used a randomized, controlled, crossover experimental design in eight adult patients with a primary diagnosis of PTSD. A script-driven imagery (SDI procedure was used to measure responsiveness to an audio-script depicting the participant's traumatic memory before and after conditions. Results: SDI activated mainly emotional processing-related brain regions (anterior insula, rostral anterior cingulate cortex (ACC, and dorsomedial prefrontal cortex, WM-related (DLPFC, and visual (association brain regions before both conditions. Although predicted pre- to post-test decrease in amygdala activation after “recall with EMs” was not significant, SDI activated less right amygdala and rostral ACC activity after “recall with EMs” compared to post-“recall-only.” Furthermore, functional connectivity from the right amygdala to the rostral ACC was decreased after “recall with EMs” compared with after “recall-only.” Conclusions: These preliminary results in a small sample

  12. Principal Component Analysis of Tissue Scores from Substances used in the COLIPA Eye Irritation Validation Study.

    Science.gov (United States)

    Lovell, D P

    1999-06-01

    Principal component analyses (PCA) have been carried out on the tissue scores from Draize eye irritation tests on the 55 formulations and chemical ingredients included in the COLIPA Eye Irritation Validation Study. A PCA was carried out on the tissue scores 24, 48 and 72 hours after instillation of the substances. The first Principal Component (PC I) explained 77% of the total variation in the tissues scores and showed a high negative correlation (r=-0.971) with the scores used to derive the Modified Maximum Average Score (MMAS). The second component (PC II) explained 7% of the total variability and contrasted corneal and iris damage with conjunctival damage as in a similar analysis carried out previously on the ECETOC databank. The third component (PCIII), while only explaining about 3% of the variability, identified individuals treated with formulations that were observed to have low corneal opacity but large corneal area scores. This may represent some particular manner of scoring at the laboratory administering the Draize test or a specific effect of some formulations. A further PCA was carried out on tissue scores from observations at 1hr to 21 days. PC I in this analysis explained 62% of the variability and there was a high negative correlation with the sum of all the tissue scores, while PC II explained 14% of the variability and contrasted damage up to 72 hours with damage after 72 hours. A number of formulations were identified with relatively low MMAS scores but tissue damage that persisted. PCA analysis is thus shown to be a powerful method for exploring complex datasets and for identification of outliers and subgroups. It has shown that the MMAS score captures most of the information on tissue scores in the first 72 hours following exposure, and it is unlikely to be of any advantage in using individual tissue scores for comparisons with alternative tests. The relationship of the classifications schemes used by three alternative methods in the COLIPA

  13. Longitudinal Relationship between Axial Length and Height in Chinese Children:Guangzhou Twin Eye Study

    Institute of Scientific and Technical Information of China (English)

    Decai Wang; Chen Zhao; Shengsong Huang; Wenyong Huang; Mingguang He

    2015-01-01

    Purpose:.To understand the growth model of axial length (AL) and height, and to explore the relationship between the two with the passage of time. Methods:.We followed twins in the Guangzhou Twin Eye Study for five years..The AL of both eyes was measured by partial coherence interferometry, and height was measured by a standard scale during each visit..A multivariate multilevel mixed model was adopted for data analysis. Results:.A total of 1217 children were included in the study. Both AL and height increased, but the rate of growth slowed down with age..The mitigation rate of height growth was -0.34 cm/year;.while that of AL growth was -0.01 mm/year. AL was positively related to height,.with a relevant coefficient of R=0.22 (Cov [height intercept, AL intercept] =1.56, 95%CI=1.14 to 1.99). The growth rates of AL and height were al-so positively related, with a relevant coefficient of R=0.18 (Cov [height slope, AL slope] =0.03, 95%CI=0.01 to 0.05). However, taller children had slower rates of height increases, with a relevant coefficient of R=-0.12 (Cov[height intercept, height slope]=-1.33,95%CI=-2.25 to-0.42); but had faster AL growth,.with a relevant coefficient of R=(Cov [height intercept, AL slope] =0.02, 95%CI=-0.05 to 0.08, R=0.02). AL and its growth rate were positively related to each other, with a relevant coefficient of R=(Cov [AL intercept,.AL slope]=0.04, 95%CI=0.03 to 0.05, R=0.3); while the growth rates of AL and height were negatively related to each other, with a relevant coefficient of R=(Cov[AL intercept, height slope]=--0.03 95%CI=-0.16 to 0.1, R=-0.02). Conclusion:.The increase in children's AL is relevant to their height increases..The faster their height increases,.the faster their AL increases.

  14. A time study of physicians' work in a German university eye hospital to estimate unit costs.

    Directory of Open Access Journals (Sweden)

    Jan Wolff

    Full Text Available Technical efficiency of hospital services is debated since performance has been heterogeneous. Staff time represents the main resource in patient care and its inappropriate allocation has been identified as a key factor of inefficiency. The aim of this study was to analyse the utilisation of physicians' work time stratified by staff groups, tasks and places of work. A further aim was to use these data to estimate resource use per unit of output.A self-reporting work-sampling study was carried during 14-days at a University Eye Hospital. Staff costs of physicians per unit of output were calculated at the wards, the operating rooms and the outpatient unit.Forty per cent of total work time was spent in contact with the patient. Thirty per cent was spent with documentation tasks. Time spent with documentation tasks declined monotonically with increasing seniority of staff. Unit costs were 56 € per patient day at the wards, 77 € and 20 € per intervention at the operating rooms for inpatients and outpatients, respectively, and 33 € per contact at the outpatient unit. Substantial differences in resources directly dedicated to the patient were found between these locations.The presented data provide unprecedented units costs in inpatient Ophthalmology. Future research should focus on analysing factors that influence differences in time allocation, such as types of patients, organisation of care processes and composition of staff.

  15. Face in profile view reduces perceived facial expression intensity: an eye-tracking study.

    Science.gov (United States)

    Guo, Kun; Shaw, Heather

    2015-02-01

    Recent studies measuring the facial expressions of emotion have focused primarily on the perception of frontal face images. As we frequently encounter expressive faces from different viewing angles, having a mechanism which allows invariant expression perception would be advantageous to our social interactions. Although a couple of studies have indicated comparable expression categorization accuracy across viewpoints, it is unknown how perceived expression intensity and associated gaze behaviour change across viewing angles. Differences could arise because diagnostic cues from local facial features for decoding expressions could vary with viewpoints. Here we manipulated orientation of faces (frontal, mid-profile, and profile view) displaying six common facial expressions of emotion, and measured participants' expression categorization accuracy, perceived expression intensity and associated gaze patterns. In comparison with frontal faces, profile faces slightly reduced identification rates for disgust and sad expressions, but significantly decreased perceived intensity for all tested expressions. Although quantitatively viewpoint had expression-specific influence on the proportion of fixations directed at local facial features, the qualitative gaze distribution within facial features (e.g., the eyes tended to attract the highest proportion of fixations, followed by the nose and then the mouth region) was independent of viewpoint and expression type. Our results suggest that the viewpoint-invariant facial expression processing is categorical perception, which could be linked to a viewpoint-invariant holistic gaze strategy for extracting expressive facial cues.

  16. Variation in genetic admixture and population structure among Latinos: the Los Angeles Latino eye study (LALES

    Directory of Open Access Journals (Sweden)

    Le Marchand Loic

    2009-11-01

    Full Text Available Abstract Background Population structure and admixture have strong confounding effects on genetic association studies. Discordant frequencies for age-related macular degeneration (AMD risk alleles and for AMD incidence and prevalence rates are reported across different ethnic groups. We examined the genomic ancestry characterizing 538 Latinos drawn from the Los Angeles Latino Eye Study [LALES] as part of an ongoing AMD-association study. To help assess the degree of Native American ancestry inherited by Latino populations we sampled 25 Mayans and 5 Mexican Indians collected through Coriell's Institute. Levels of European, Asian, and African descent in Latinos were inferred through the USC Multiethnic Panel (USC MEP, formed from a sample from the Multiethnic Cohort (MEC study, the Yoruba African samples from HapMap II, the Singapore Chinese Health Study, and a prospective cohort from Shanghai, China. A total of 233 ancestry informative markers were genotyped for 538 LALES Latinos, 30 Native Americans, and 355 USC MEP individuals (African Americans, Japanese, Chinese, European Americans, Latinos, and Native Hawaiians. Sensitivity of ancestry estimates to relative sample size was considered. Results We detected strong evidence for recent population admixture in LALES Latinos. Gradients of increasing Native American background and of correspondingly decreasing European ancestry were observed as a function of birth origin from North to South. The strongest excess of homozygosity, a reflection of recent population admixture, was observed in non-US born Latinos that recently populated the US. A set of 42 SNPs especially informative for distinguishing between Native Americans and Europeans were identified. Conclusion These findings reflect the historic migration patterns of Native Americans and suggest that while the 'Latino' label is used to categorize the entire population, there exists a strong degree of heterogeneity within that population, and that

  17. Establishing the tolerability and performance of tamarind seed polysaccharide (TSP in treating dry eye syndrome: results of a clinical study

    Directory of Open Access Journals (Sweden)

    Valente Cristiana

    2007-03-01

    Full Text Available Abstract Background One of the problems arising from available preparations for dry eye syndrome is the limited residence time of products on the ocular surface. In this paper, we look at an innovative new treatment for dry eye, tamarind seed polysaccharide (TSP. TSP possesses mucomimetic, mucoadhesive and pseudoplastic properties. The 'mucin-like' molecular structure of TSP is similar to corneal and conjunctival mucin 1 (MUC1, a transmembrane glycoprotein thought to play an essential role in protecting and wetting the corneal surface and may explain its increased retention on the eye surface. Methods The activity of TSP and hyaluronic acid (HA in the treatment of dry eye syndrome was compared in an open-label, randomised, single-centre clinical study. Thirty patients were randomised to receive three or more applications per day of either TSP 0.5%, TSP 1% or HA 0.2% (Hyalistil™ over a period of 90 days. The primary objective of tolerability was assessed by visual analogue scale (VAS, scoring of specific symptoms and the incidence of adverse events. Secondary objectives included improvement in stability of the precorneal tear film, subjective symptoms and corneal and conjunctival staining. Results TSP 0.5% and 1% were comparable to HA 0.2% with regard to both primary and secondary objective parameters. TSP 1% showed benefits over HA 0.2% for the subjective symptoms; trouble blinking, ocular burning and foreign body sensation. Conclusion This study suggests that TSP 0.5% and 1% offer at least equivalent relief to HA 0.2% for dry eye syndrome. All treatments demonstrated optimal tolerability and are suitable for frequent use in the therapy of dry eye. TSP 1% produced promising results in terms of improvements in certain patient symptoms and suggests benefits of the TSP formulation. This study paves the way for a larger study to further establish the performance and safety of TSP compared with HA and highlights the need to expand this therapeutic

  18. The Impact of Language Opacity and Proficiency on Reading Strategies in Bilinguals: An Eye Movement Study

    Science.gov (United States)

    de León Rodríguez, Diego; Buetler, Karin A.; Eggenberger, Noëmi; Laganaro, Marina; Nyffeler, Thomas; Annoni, Jean-Marie; Müri, René M.

    2016-01-01

    Reading strategies vary across languages according to orthographic depth – the complexity of the grapheme in relation to phoneme conversion rules – notably at the level of eye movement patterns. We recently demonstrated that a group of early bilinguals, who learned both languages equally under the age of seven, presented a first fixation location (FFL) closer to the beginning of words when reading in German as compared with French. Since German is known to be orthographically more transparent than French, this suggested that different strategies were being engaged depending on the orthographic depth of the used language. Opaque languages induce a global reading strategy, and transparent languages force a local/serial strategy. Thus, pseudo-words were processed using a local strategy in both languages, suggesting that the link between word forms and their lexical representation may also play a role in selecting a specific strategy. In order to test whether corresponding effects appear in late bilinguals with low proficiency in their second language (L2), we present a new study in which we recorded eye movements while two groups of late German–French and French–German bilinguals read aloud isolated French and German words and pseudo-words. Since, a transparent reading strategy is local and serial, with a high number of fixations per stimuli, and the level of the bilingual participants’ L2 is low, the impact of language opacity should be observed in L1. We therefore predicted a global reading strategy if the bilinguals’ L1 was French (FFL close to the middle of the stimuli with fewer fixations per stimuli) and a local and serial reading strategy if it was German. Thus, the L2 of each group, as well as pseudo-words, should also require a local and serial reading strategy. Our results confirmed these hypotheses, suggesting that global word processing is only achieved by bilinguals with an opaque L1 when reading in an opaque language; the low level in the L2

  19. Eye care infrastructure and human resources for managing diabetic retinopathy in India: The India 11-city 9-state study

    Science.gov (United States)

    Gilbert, Clare E.; Babu, R. Giridhara; Gudlavalleti, Aashrai Sai Venkat; Anchala, Raghupathy; Shukla, Rajan; Ballabh, Pant Hira; Vashist, Praveen; Ramachandra, Srikrishna S.; Allagh, Komal; Sagar, Jayanti; Bandyopadhyay, Souvik; Murthy, G. V. S.

    2016-01-01

    Background: There is a paucity of information on the availability of services for diagnosis and management of diabetic retinopathy (DR) in India. Objectives: The study was undertaken to document existing healthcare infrastructure and practice patterns for managing DR. Methods: This cross-sectional study was conducted in 11 cities and included public and private eye care providers. Both multispecialty and stand-alone eye care facilities were included. Information was collected on the processes used in all steps of the program, from how diabetics were identified for screening through to policies about follow-up after treatment by administering a semistructured questionnaire and by using observational checklists. Results: A total of 86 eye units were included (31.4% multispecialty hospitals; 68.6% stand-alone clinics). The availability of a dedicated retina unit was reported by 68.6% (59) facilities. The mean number of outpatient consultations per year was 45,909 per responding facility, with nearly half being new registrations. A mean of 631 persons with sight-threatening-DR (ST-DR) were registered per year per facility. The commonest treatment for ST-DR was laser photocoagulation. Only 58% of the facilities reported having a full-time retina specialist on their rolls. More than half the eye care facilities (47; 54.6%) reported that their ophthalmologists would like further training in retina. Half (51.6%) of the facilities stated that they needed laser or surgical equipment. About 46.5% of the hospitals had a system to track patients needing treatment or for follow-up. Conclusions: The study highlighted existing gaps in service provision at eye care facilities in India. PMID:27144134

  20. Children’s and Adolescents’ Processing of Temporary Syntactic Ambiguity: An Eye Movement Study

    Directory of Open Access Journals (Sweden)

    Paul E. Engelhardt

    2014-01-01

    Full Text Available This study examined the eye movements of 24 children and adolescents as they read sentences containing temporary syntactic ambiguities. Prior research suggested that children primarily use grammatical information when making initial parsing decisions, and they tend to disregard semantic and contextual information. On each trial, participants read a garden path sentence (e.g., While the storm blew the boat sat in the shed, and, afterwards, they answered a comprehension question (e.g., Did the storm blow the boat?. The design was 2 × 2 (verb type × ambiguity repeated measures. Verb type was optionally transitive or reflexive, and sentences were ambiguous or unambiguous. Results showed no differences in first pass reading times at the disambiguating verb (e.g., sat. However, regressions did show a significant interaction. The unambiguous-reflexive condition had approximately half the number of regressions, suggesting less processing difficulty in this condition. Developmentally, we found that adolescents had significantly better comprehension, which seemed to be linked to the increased tendency to regress from the disambiguating word. Findings are consistent with the assumption that the processing architecture is more restricted in children compared to adolescents. In addition, results indicated that variance in ambiguity resolution was associated with interference control but not working memory.

  1. Novel models for studying the blood-brain and blood-eye barriers in Drosophila.

    Science.gov (United States)

    Pinsonneault, Robert L; Mayer, Nasima; Mayer, Fahima; Tegegn, Nebiyu; Bainton, Roland J

    2011-01-01

    In species as varied as humans and flies, humoral/central nervous system barrier structures are a major obstacle to the passive penetration of small molecules including endogenous compounds, environmental toxins, and drugs. In vivo measurement of blood-brain physiologic function in vertebrate animal models is difficult and current ex vivo models for more rapid experimentation using, for example, cultured brain endothelial cells, only partially reconstitute the anatomy and physiology of a fully intact blood-brain barrier (BBB). To address these problems, we and others continue to develop in vivo assays for studying the complex physiologic function of central nervous system (CNS) barriers using the fruit fly Drosophila melanogaster (Dm). These methods involve the introduction of small molecule reporters of BBB physiology into the fly humoral compartment by direct injection. Since these reporters must cross the Dm BBB in order to be visible in the eye, we can directly assess genetic or chemical modulators of BBB function by monitoring retinal fluorescence. This assay has the advantage of utilizing a physiologically intact BBB in a model organism that is economical and highly amenable to genetic manipulation. In combination with other approaches outlined here, such as brain dissection and behavioral assessment, one can produce a fuller picture of BBB biology and physiology. In this chapter, we provide detailed methods for examining BBB biology in the fly, including a Dm visual assay to screen for novel modulators of the BBB.

  2. Effect of Cycloplegia on the Refractive Status of Children: The Shandong Children Eye Study

    Science.gov (United States)

    Hu, Yuan Yuan; Wu, Jian Feng; Lu, Tai Liang; Wu, Hui; Sun, Wei; Wang, Xing Rong

    2015-01-01

    Purpose To determine the effect of 1% cyclopentolate on the refractive status of children aged 4 to 18 years. Methods Using a random cluster sampling in a cross-sectional school-based study design, children with an age of 4–18 years were selected from kindergardens, primary schools, junior and senior high schools in a rural county and a city. Auto-refractometry was performed before and after inducing cycloplegia which was achieved by 1% cyclopentolate eye drops. Results Out of 6364 eligible children, data of 5999 (94.3%) children were included in the statistical analysis. Mean age was 10.0±3.3 years (range: 4–18 years). Mean difference between cycloplegic and non-cycloplegic refractive error (DIFF) was 0.78±0.79D (median: 0.50D; range: -1.00D to +10.75D). In univariate analysis, DIFF decreased significantly with older age (Prefractometric measures lead to a misclassification of refractive error in a significant proportion of children. PMID:25658329

  3. Structure modulates similarity-based interference in sluicing: An eye tracking study.

    Directory of Open Access Journals (Sweden)

    Jesse A. Harris

    2015-12-01

    Full Text Available In cue-based content-addressable approaches to memory, a target and its competitors are retrieved in parallel from memory via a fast, associative cue-matching procedure under a severely limited focus of attention. Such a parallel matching procedure could in principle ignore the serial order or hierarchical structure characteristic of linguistic relations. I present an eye tracking while reading experiment that investigates whether the sentential position of a potential antecedent modulates the strength of similarity-based interference, a well-studied effect in which increased similarity in features between a target and its competitors results in slower and less accurate retrieval overall. The manipulation trades on an independently established Locality bias in sluiced structures to associate a wh-remnant (which ones in clausal ellipsis with the most local correlate (some wines, as in The tourists enjoyed some wines, but I don’t know which ones. The findings generally support cue-based parsing models of sentence processing that are subject to similarity-based interference in retrieval, and provide additional support to the growing body of evidence that retrieval is sensitive to both the structural position of a target antecedent and its competitors, and the specificity of retrieval cues.

  4. BARRIERS RESPONSIBLE FOR DELAYED UTILIZATION OF CATARACT SURGERY: AN EYE CAMP STUDY FROM CENTRAL INDIA

    Directory of Open Access Journals (Sweden)

    Umesh

    2014-03-01

    Full Text Available INTRODUCTION: Blindness is one of the significant social problems in India with 7 million of the total 45 million blind people in the world residing in our country. Apart from health and status of vision, there are many other socio-economic factors and perceptions, which influence the decision making of the people for getting operated for cataract. But very few studies have been done on the social factors influencing the utilization of cataract surgery. MATERIAL AND METHODS: It was a hospital-based, descriptive study. The study subjects were recruited from the Ophthalmology department from cataract camp held in Chirayu medical College, Hospital during October 2013 to January 2014. RESULTS: In present study, insufficient family income and no one to accompany (60% and 10% was responded by majority of the subjects. In present study, the barriers for delayed utilization of cataract surgery like could manage to do daily work was responded by 513 (85.5% out of total 600 subjects, could see with the other eye clearly 470 (78.3%, busy with work 118 (19.6%, being female70 (11.6%, fear of surgery 115 (19.1%, old age 200 (33.3%, fear that surgery could lead to loss of eyesight 55 (9.1%, it was Gods will 35 (5.8%, fear about the cost of surgery 375 (62.5% and fear that surgery could lead to death was responded by 15 (2.5% out of total 600 subjects. CONCLUSION: Expansion of outreach programmes to different communities rather than concentrate in urban areas, and offering cataract surgical services at affordable rates will also be of help. Health Education has a great role to play as well, especially in creating awareness. Adequate dissemination of information through various media is usually will be very helpful

  5. Epidemiology of Oestrus ovis (Diptera: Oestridae in sheep in Botucatu, State of São Paulo Epidemiologia de Oestrus ovis (Diptera: Oestridae em ovinos em Botucatu, São Paulo

    Directory of Open Access Journals (Sweden)

    Bruna Fernanda da Silva

    2012-12-01

    Full Text Available The seasonal factors that influence Oestrus ovis infestation in sheep were determined in Botucatu, State of São Paulo, Southwestern Brazil, from April 2008 to March 2011. Two tracer lambs were monthly exposed to natural infestation by O. ovis larvae for 28 consecutive days, by grazing with a sheep flock. Tracer animals were then euthanized and the larvae of O. ovis recovered from nasal and sinus cavities. Of the 72 tracer lambs, 50% were infested with O. ovis larvae and the mean intensity of infestation per head infested was 16.8 larvae, with an average of 7.8 L1, 5.3 L2 and 3.7 L3. O. ovis larvae were present during the four seasons of the year, but the mean larval burden was significantly higher during the spring and summer months, compared to winter (P Os fatores sazonais que influenciam a infestação por larvas de Oestrus ovis, foram determinados no período de abril de 2008 a março de 2011, em ovinos criados em Botucatu, São Paulo, região Sudeste do Brasil. Mensalmente, dois cordeiros traçadores permaneceram em pastejo com um rebanho ovino durante 28 dias consecutivos, expostos à infestação natural por larvas de O. ovis. Em seguida, os cordeiros foram sacrificados, e as larvas de O. ovis recuperadas da cavidade nasal e seios frontais. Dos 72 cordeiros traçadores, 50% estavam infestados por larvas de O. ovis, com intensidade média de infestação de 16,8 larvas/cabeça infestada, com média de 7,8 L1, 5,3 L2 e 3,7 L3. As larvas de O. ovis foram recuperadas durante as quatro estações do ano, mas o número médio de larvas foi significativamente superior durante os meses de primavera e verão comparado aos meses de inverno (P < 0,05. A maior taxa de recuperação larval coincidiu com temperaturas médias entre 20 °C e 25 °C e umidade relativa do ar por volta de 70%. Os resultados sugerem que a evolução e desenvolvimento de O. ovis ocorre praticamente durante o ano inteiro, mas a infestação é mais frequente nos meses de

  6. Características dos frutos de cultivares de pessegueiros e nectarineira, no município de Botucatu – SP

    OpenAIRE

    Ramos, Dayana Portes [UNESP; Leonel,Sarita

    2008-01-01

    The research had as purpose to evaluate the fruits physical-chemical characteristics of peach cultivars (CP-9553 CYN, CP951 C, Tropic Beauty, Cascata 953, Cascata 797, Cascata 587, Precocinho, Conserva 693, Diamante Mejorado, Turmalina e Marli and Sun Blaze nectarine at Botucatu, São Paulo, Brazil region. It were evaluated the fruits fresh matter, longitudinal and transversal diameters, and the crop period. In relation the physical-chemical characteristics of fruits, it was evaluated the text...

  7. Effect of birth parameters on retinal vascular caliber: the Twins Eye Study in Tasmania.

    Science.gov (United States)

    Sun, Cong; Ponsonby, Anne-Louise; Wong, Tien Y; Brown, Shayne A; Kearns, Lisa S; Cochrane, Jenny; MacKinnon, Jane R; Ruddle, Jonathan B; Hewitt, Alex W; Liew, Gerald; Dwyer, Terence; Scurrah, Katrina; Mackey, David A

    2009-03-01

    Recent studies reported an association between smaller birth size and narrower retinal vascular caliber, but it remains unclear whether this association is attributed to confounding by shared environment or genetic factors. At a mean age of 9.3 years, 266 twins (49 monozygotic and 84 dizygotic pairs) in the Twins Eye Study in Tasmania underwent an ophthalmic examination including retinal photography. Retinal vascular caliber was measured using a validated protocol. The majority of these twins were also in the Tasmanian Infant Health Study, which prospectively collected data on birth parameters and antenatal maternal factors. We conducted the main analysis using linear mixed models, accounting for birth set clustering. Both the within-pair (-9.73; 95% CI: -14.68 to -4.77 microm per 5-cm decrease in birth length) and between-pair associations (-7.15; 95% CI: -11.54 to -3.01) with retinal arteriolar caliber were significant and of similar magnitude (difference in effect, P=0.61), after adjusting for age, sex, maternal smoking, mean arterial blood pressure, and other confounders. These associations remained within dizygotic and monozygotic pairs. Analyses of head circumference and retinal arteriolar caliber were similar to those of birth length (within-pair regression coefficient: -2.41; 95% CI: -5.09 to 0.28; between-pair regression coefficient: -2.60; 95% CI: -5.00 to -0.19). For birth weight, only a between-pair association was evident (-7.28; 95% CI: -13.07 to -1.48). This study demonstrates a consistent association between smaller birth size and narrower retinal arterioles in twins. The independent effect of shorter birth length on retinal arteriolar caliber supports a role for twin-specific supply line factors affecting fetal growth on vascular structure.

  8. Electron dose distributions caused by the contact-type metallic eye shield: Studies using Monte Carlo and pencil beam algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sei-Kwon; Yoon, Jai-Woong; Hwang, Taejin; Park, Soah; Cheong, Kwang-Ho; Jin Han, Tae; Kim, Haeyoung; Lee, Me-Yeon; Ju Kim, Kyoung, E-mail: kjkim@hallym.or.kr; Bae, Hoonsik

    2015-10-01

    A metallic contact eye shield has sometimes been used for eyelid treatment, but dose distribution has never been reported for a patient case. This study aimed to show the shield-incorporated CT-based dose distribution using the Pinnacle system and Monte Carlo (MC) calculation for 3 patient cases. For the artifact-free CT scan, an acrylic shield machined as the same size as that of the tungsten shield was used. For the MC calculation, BEAMnrc and DOSXYZnrc were used for the 6-MeV electron beam of the Varian 21EX, in which information for the tungsten, stainless steel, and aluminum material for the eye shield was used. The same plan was generated on the Pinnacle system and both were compared. The use of the acrylic shield produced clear CT images, enabling delineation of the regions of interest, and yielded CT-based dose calculation for the metallic shield. Both the MC and the Pinnacle systems showed a similar dose distribution downstream of the eye shield, reflecting the blocking effect of the metallic eye shield. The major difference between the MC and the Pinnacle results was the target eyelid dose upstream of the shield such that the Pinnacle system underestimated the dose by 19 to 28% and 11 to 18% for the maximum and the mean doses, respectively. The pattern of dose difference between the MC and the Pinnacle systems was similar to that in the previous phantom study. In conclusion, the metallic eye shield was successfully incorporated into the CT-based planning, and the accurate dose calculation requires MC simulation.

  9. Perspectivas da Medicina Tradicional e das práticas contemplativas na faculdade de medicina de Botucatu, UNESP

    Directory of Open Access Journals (Sweden)

    Thaís Bassi Cardoso

    2012-06-01

    Full Text Available Introdução: A designação de saúde como “ausência de doença” sofreu uma alteração desde a criação da OMS, definindo-a como “o estado do mais completo bem-estar físico, mental e social e não apenas a ausência de enfermidade”. A partir da década de 70, houve a hipervalorização do atendimento terciário em saúde e do tecnocentrismo, evidente com o processo de hospitalização e da tecnologia de ponta. Apesar de todo o avanço alcançado, tem-se observado um movimento considerável em várias partes do mundo em relação ao ensino e utilização de terapêuticas relacionadas à Medicina Tradicional (MT e às Práticas Contemplativas (PC. Objetivo:Descrever as perspectivas da MT e das PC na Faculdade de Medicina de Botucatu (FMB, a partir da análise das ações que iniciaram a discussão sobre o tema. Metodologia: Análise descritiva e reflexiva dos fatos acadêmicos relacionados à MT e às PC que ocorreram na FMB. Resultados: Apesar do Hospital das Clínicas de Botucatu oferecer gratuitamente, desde 2000, atendimento homeopático e acupuntura, tendo atendido mais de 7000 pacientes, os graduandos não tinham a oportunidade de acompanhar o serviço. As práticas existentes eram restritas aos ambulatórios e não havia disciplinas optativas ou matérias curriculares oferecidas aos estudantes.A partir da demanda foram formados grupos de estudo sobre Homeopatia, Medicina Antroposófica e Espiritualidade. A fim de prover uma acessibilidade maior ao tema, em 2011 foi criada a Liga da Medicina Integrativa e Complementar. No mesmo ano ocorreram ainda o “I Congresso Médico Acadêmico de Acupuntura e Homeopatia”, além de uma noite dedicada ao tema da Medicina Integrativa no 20° Congresso Médico Acadêmico de Botucatu. Conclusões:Incentivar o acesso ao conhecimento das abordagens que compõem a MT e as PC, não é apenas seguir uma tendência mundial, mas sim disponibilizar aos estudantes a possibilidade de um aprendizado que

  10. Location and composition of haptics of posterior chamber intraocular lenses. Histopathologic study of postmortem eyes.

    Science.gov (United States)

    McDonnell, P J; Champion, R; Green, W R

    1987-02-01

    Of 110 eyes with posterior chamber intraocular lenses (IOLs) examined postmortem, 37% had both haptics outside of the capsular bag; 57% had one haptic in the capsular bag and the other haptic outside of the bag. Typically, these optics were decentered by 1 to 2 mm. Only six eyes (5%) had both haptics within the capsular bag. Erosion into the ciliary sulcus produced obliteration of the major arterial circle of the iris in 12 eyes (11%). The local tissue response to eroding haptics was similar for haptics composed of polypropylene and haptics composed of polymethylmethacrylate (PMMA). The authors found considerable discrepancy between the actual location of haptics and the surgeon's desired location (i.e., capsular bag or ciliary sulcus). Most of these cases were clinically successful.

  11. Visual attention to emotional face in schizophrenia: an eye tracking study.

    Directory of Open Access Journals (Sweden)

    Mania Asgharpour

    2015-03-01

    Full Text Available Deficits in the processing of facial emotions have been reported extensively in patients with schizophrenia. To explore whether restricted attention is the cause of impaired emotion processing in these patients, we examined visual attention through tracking eye movements in response to emotional and neutral face stimuli in a group of patients with schizophrenia and healthy individuals. We also examined the correlation between visual attention allocation and symptoms severity in our patient group.Thirty adult patients with schizophrenia and 30 matched healthy controls participated in this study. Visual attention data were recorded while participants passively viewed emotional-neutral face pairs for 500 ms. The relationship between the visual attention and symptoms severity were assessed by the Positive and Negative Syndrome Scale (PANSS in the schizophrenia group. Repeated Measures ANOVAs were used to compare the groups.Comparing the number of fixations made during face-pairs presentation, we found that patients with schizophrenia made fewer fixations on faces, regardless of the expression of the face. Analysis of the number of fixations on negative-neutral pairs also revealed that the patients made fewer fixations on both neutral and negative faces. Analysis of number of fixations on positive-neutral pairs only showed more fixations on positive relative to neutral expressions in both groups. We found no correlations between visual attention pattern to faces and symptom severity in schizophrenic patients.The results of this study suggest that the facial recognition deficit in schizophrenia is related to decreased attention to face stimuli. Finding of no difference in visual attention for positive-neutral face pairs between the groups is in line with studies that have shown increased ability to positive emotional perception in these patients.

  12. The perceptual saliency of fearful eyes and smiles: A signal detection study

    Science.gov (United States)

    Saban, Muhammet Ikbal; Rotshtein, Pia

    2017-01-01

    Facial features differ in the amount of expressive information they convey. Specifically, eyes are argued to be essential for fear recognition, while smiles are crucial for recognising happy expressions. In three experiments, we tested whether expression modulates the perceptual saliency of diagnostic facial features and whether the feature’s saliency depends on the face configuration. Participants were presented with masked facial features or noise at perceptual conscious threshold. The task was to indicate whether eyes (experiments 1-3A) or a mouth (experiment 3B) was present. The expression of the face and its configuration (i.e. spatial arrangement of the features) were manipulated. Experiment 1 compared fearful with neutral expressions, experiments 2 and 3 compared fearful versus happy expressions. The detection accuracy data was analysed using Signal Detection Theory (SDT), to examine the effects of expression and configuration on perceptual precision (d’) and response bias (c), separately. Across all three experiments, fearful eyes were detected better (higher d’) than neutral and happy eyes. Eyes were more precisely detected than mouths, whereas smiles were detected better than fearful mouths. The configuration of the features had no consistent effects across the experiments on the ability to detect expressive features. But facial configuration affected consistently the response bias. Participants used a more liberal criterion for detecting the eyes in canonical configuration and fearful expression. Finally, the power in low spatial frequency of a feature predicted its discriminability index. The results suggest that expressive features are perceptually more salient with a higher d’ due to changes at the low-level visual properties, with emotions and configuration affecting perception through top-down processes, as reflected by the response bias. PMID:28267761

  13. EVALUATION OF COLOR SETTINGS IN AERIAL IMAGES WITH THE USE OF EYE-TRACKING USER STUDY

    Directory of Open Access Journals (Sweden)

    J. Mirijovsky

    2016-06-01

    Respondents’ answers were evaluated and the most realistic and most preferable color settings were found. The advantage of the eye-tracking evaluation was that also the process of the selection of the answers was analyzed. Areas of Interest were marked around each image in the grid and the sequences of gaze movements were analyzed. Sequence chart was used for visualization and eye-tracking metrics were statistically tested. The presented paper shows the differences in the perception and preferences of aerial images with different color settings.

  14. Tectal codification of eye movements in goldfish studied by electrical microstimulation. f.

    Science.gov (United States)

    Salas, C; Herrero, L; Rodriguez, F; Torres, B

    1997-05-01

    This work compares the tectal codification of eye movements in goldfish with those reported for other vertebrate groups. Focal electrical stimulation was applied in various tectal zones and the characteristics of evoked eye movements were examined as a function of (i) the position of the stimulation over the tectal surface, (ii) the initial position of the eyes and (iii) the parameters (pulse rate, current strength, duration) of the stimulus. In a large medial zone, stimulation within the intermediate and deep layers of the tectum evoked contraversive saccades of both eyes, whose direction and amplitude were roughly congruent with the retinotopic representation of the visual world within overlying layers. These saccades were minimally influenced by the initial position of the eye in the orbit. The topographical arrangement of evoked saccades and body movements suggests that this tectal zone triggers orienting responses in a similar way to those described in other vertebrates. Stimulations applied within the caudal tectum also evoked contraversive saccades, but in disagreement with the overlying retinotopic map--the vertical component was absent. Taken together with electrically evoked body movements reported in free-swimming fish, these saccades could reveal that this zone is involved in escape responses. When stimulations were applied within the anteromedial zone of the tectum, contraversive movements of both eyes appeared much more dependent on initial eye position. Saccades elicited from this area displayed characteristics of "goal-directed saccades" which were similar to those described in the cat. The generation of goal-directed movements from the anteromedial zone suggests that this portion of the goldfish optic tectum has a different intrinsic organization or is connected with the brainstem saccade generator in a different fashion than the medial zone. Finally, stimulation of the extreme anteromedial zone evoked convergent eye movements. These movements and

  15. Recognition of Facial Expressions in Individuals with Elevated Levels of Depressive Symptoms: An Eye-Movement Study

    OpenAIRE

    2012-01-01

    Previous studies consistently reported abnormal recognition of facial expressions in depression. However, it is still not clear whether this abnormality is due to an enhanced or impaired ability to recognize facial expressions, and what underlying cognitive systems are involved. The present study aimed to examine how individuals with elevated levels of depressive symptoms differ from controls on facial expression recognition and to assess attention and information processing using eye trackin...

  16. Comparative Study of Sustained Attentional Bias on Emotional Processing in ADHD Children to Pictures with Eye-Tracking

    OpenAIRE

    Pishyareh, Ebrahim; Mehdi EHRANI-DOOST; MAHMOODI-GHARAIE, Javad; Anahita KHORRAMI; Saeid Reza RAHMDAR

    2015-01-01

    How to Cite This Article: Pishyareh E, Tehrani-doost M, Mahmoodi-gharaie J, Khorrami A, Rahmdar SR. A Comparative Study of SustainedAttentional Bias on Emotional Processing in ADHD Children to Pictures with Eye-Tracking. Iran J Child Neurol. 2015 Winter;9(1):64-70.AbstractObjectiveADHD children have anomalous and negative behavior especially in emotionally related fields when compared to other. Evidence indicates that attention has an impact on emotional processing. The present study evaluate...

  17. Control of parasitic infections among school children in the peri-urban area of Botucatu, São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Regina Coeli Cunha Dórea

    1996-10-01

    Full Text Available Tide prevalence of intestinal parasitosis ivas investigated in a primaiy school located in Rubiâo Júnior, a peri-urban district of Botucatu, São Paulo slate, Brazil, in order to assess the effect of treatment and practical measures of prophylaxis in the control of parasitic infections among 7-to- 18-year-old school children of a low socio-economic status. The first series of parasitological examinations included 219 school children, ef which 123 (56.1 % were found to be infected with one or more parasite species. Eighty- four children canying pathogenic parasites were submitted to various anti-parasitic treatment schedules. We re-evaluated 15 (89 % students after 4 to 6 months post- chemotherapy. The results indicate that the combination of treatment with prophylactic measures has been successful in the control of parasitic infections, since reinfection rates were generally low ( 73-1 % in children infected with most parasite species. The reasons for the apparent failure in the control of infections caused by Hymenolepis nana and Strongyloides stercoralis are discussed.Prôcedeu-se o estudo da prevalência de enteroparasitoses entre escolares de 7 a 18 anos, de condições sõcio-econômicas baixas e residentes no distritoperi-urbano de Rubião Júnior, município de Botucatu, São Paulo, com o objetivo de analisar o papel de medidas profiláticas e terapêuticas no controle das parasitoses diagnosticadas. Dos 219 alunos estudados na primeira avaliação parasitolõgica, 123 (56.1% mostraram-se positivos para unia ou mais parasitoses. O tratamento foi aplicado para 84 escolares, por serem estes portadores de parasitos patogênicos. A segunda avaliação parasitolõgica foi realizada 4 a 6 meses após o tratamento em 75 (89% escolares. Os resultados indicam que o uso combinado do tratamento e medidas profiláticas foi capaz de limitar a ocorrência de novas infecções para níveis 73-1% foram encontradas para a maioria das parasitoses, exceto

  18. Desired and Undesired Effects of Energy Labels--An Eye-Tracking Study.

    Directory of Open Access Journals (Sweden)

    Signe Waechter

    Full Text Available Saving energy is an important pillar for the mitigation of climate change. Electric devices (e.g., freezer and television are an important player in the residential sector in the final demand for energy. Consumers' purchase decisions are therefore crucial to successfully reach the energy-efficiency goals. Putting energy labels on products is often considered an adequate way of empowering consumers to make informed purchase decisions. Consequently, this approach should contribute to reducing overall energy consumption. The effectiveness of its measurement depends on consumers' use and interpretation of the information provided. Despite advances in energy efficiency and a mandatory labeling policy, final energy consumption per capita is in many countries still increasing. This paper provides a systematic analysis of consumers' reactions to one of the most widely used eco-labels, the European Union (EU energy label, by using eye-tracking methodology as an objective measurement. The study's results partially support the EU's mandatory policy, showing that the energy label triggers attention toward energy information in general. However, the energy label's effect on consumers' actual product choices seems to be rather low. The study's results show that the currently used presentation format on the label is insufficient. The findings suggest that it does not facilitate the integration of energy-related information. Furthermore, the current format can attract consumers to focus more on energy-efficiency information, leading them to disregard information about actual energy consumption. As a result, the final energy consumption may increase because excellent ratings on energy efficiency (e.g., A++ do not automatically imply little consumption. Finally, implications for policymakers and suggestions for further research are discussed.

  19. Desired and Undesired Effects of Energy Labels--An Eye-Tracking Study.

    Science.gov (United States)

    Waechter, Signe; Sütterlin, Bernadette; Siegrist, Michael

    2015-01-01

    Saving energy is an important pillar for the mitigation of climate change. Electric devices (e.g., freezer and television) are an important player in the residential sector in the final demand for energy. Consumers' purchase decisions are therefore crucial to successfully reach the energy-efficiency goals. Putting energy labels on products is often considered an adequate way of empowering consumers to make informed purchase decisions. Consequently, this approach should contribute to reducing overall energy consumption. The effectiveness of its measurement depends on consumers' use and interpretation of the information provided. Despite advances in energy efficiency and a mandatory labeling policy, final energy consumption per capita is in many countries still increasing. This paper provides a systematic analysis of consumers' reactions to one of the most widely used eco-labels, the European Union (EU) energy label, by using eye-tracking methodology as an objective measurement. The study's results partially support the EU's mandatory policy, showing that the energy label triggers attention toward energy information in general. However, the energy label's effect on consumers' actual product choices seems to be rather low. The study's results show that the currently used presentation format on the label is insufficient. The findings suggest that it does not facilitate the integration of energy-related information. Furthermore, the current format can attract consumers to focus more on energy-efficiency information, leading them to disregard information about actual energy consumption. As a result, the final energy consumption may increase because excellent ratings on energy efficiency (e.g., A++) do not automatically imply little consumption. Finally, implications for policymakers and suggestions for further research are discussed.

  20. VAZÕES ESPECÍFICAS MÍNIMAS PARA SECAGEM DO MILHO COM AR NATURAL EM BOTUCATU-SP MINIMUM AIRFLOW RATES TO DRY CORN GRAIN WITH NATURAL AIR IN BOTUCATU-SP

    Directory of Open Access Journals (Sweden)

    V. A. Gonçalves

    2007-09-01

    Full Text Available

    Recomendam-se à secagem com ar natural vazões específicas suficientemente baixas, reduzindo a potência requerida pelo ventilador e contribuindo para o arrefecimento da sobressecagem. Através de modelos matemáticos de simulação foram determinadas as vazões específicas mínimas necessárias à secagem com ar natural do milho a granel, nas condições climáticas do município de Botucatu, no Estado de São Paulo, correspondentes aos meses de março a junho do ano de 1971, cujo potencial de secagem foi o mais drástico dentro de um período de 10 anos analisado. Foram considerados para o milho os teores de umidade inicial, base úmida, de 22%, 20% e 18%, obtendo-se os respectivos períodos de armazenamento seguro de 7, 11 e 29 dias, em função da temperatura média de 23,40C do mês de março de 1975, a mais elevada do período de 10 anos analisado. Outrossim, as médias empregadas, temperatura de bulbo seco e umidade relativa, foram obtidas a partir dos registros horários do termo-higrógrafo, localizado na Estação Meteorológica da Faculdade de Ciências Agronômicas de Botucatu, no Estado de São Paulo. Foi considerada somente a secagem seletiva dentro dos períodos diários das 9 às 17 horas, 9 às 18 horas e 8 às 18 horas, dada a impossibilidade de realização da secagem contínua, já que as condições de equilíbrio entre o ar e o grão não possibilitaram a redução do teor de umidade final ao nível recomendado ao armazenamento seguro. Constatou-se que a queda do teor de umidade de equilíbrio do grão em poucos pontos percentuais acarreta elevados decrementos nas vazões específicas mínimas requeridas. Outrossim, uma redução de poucas horas no período diário de operação do ventilador requer significativos incrementos nas vazões específicas mínimas para a realização da secagem dentro do tempo de secagem admissível.

  1. Effects of Saccadic Bilateral Eye Movements on Memory in Children and Adults: An Exploratory Study

    Science.gov (United States)

    Parker, Andrew; Dagnall, Neil

    2012-01-01

    The effects of saccadic bilateral (horizontal) eye movements on true and false memory in adults and children were investigated. Both adults and children encoded lists of associated words in the Deese-Roediger-McDermott paradigm followed by a test of recognition memory. Just prior to retrieval, participants were asked to engage in 30 s of bilateral…

  2. Towards Diagram Understanding: A Pilot Study Measuring Cognitive Workload Through Eye-Tracking

    DEFF Research Database (Denmark)

    Maier, Anja; Baltsen, Nick; Christoffersen, Henrik;

    2014-01-01

    measurements and subjective assessments; here, we also investigate behavioral indicators such as fixation and pupillary dilation. We use such indicators to explore diagram understanding- and reading strategies and how such strategies are impacted, e.g. by diagram type and expertise level. In the pilot eye...

  3. Malignant tumors of the eye and adnexa, morbidity and mortality (population-based study

    Directory of Open Access Journals (Sweden)

    V. M. Merabishvili

    2014-07-01

    Full Text Available For the first time in Russia there are presented data on dynamics of morbidity and mortality from malignant tumors of the eye and adnexa (С69. there were demonstrated details of prevalence by age groups of patients, provided characteristics of dynamics of the levels of morphological verification and distribution of patients by stages of tumor process.

  4. Morphosyntactic Development in a Second Language: An Eye-Tracking Study on the Role of Attention

    Science.gov (United States)

    Issa, Bernard Ibrahim, II

    2015-01-01

    One common claim in second language (L2) acquisition research is that attention is crucial for development to occur. Although previous empirical research supports this claim, methodological approaches have not been able to directly measure attention. This thesis utilized eye-tracking to directly measure attention and thus provide converging…

  5. The Effect of Autologous Platelet Lysate Eye Drops: An In Vivo Confocal Microscopy Study

    Science.gov (United States)

    Fea, Antonio M.; Testa, Valeria; Machetta, Federica; Parisi, Simone; D'Antico, Sergio; Spinetta, Roberta; Fusaro, Enrico; Grignolo, Federico M.

    2016-01-01

    Purpose. To determine the effectiveness of autologous platelet lysate (APL) eye drops in patients with primary Sjögren syndrome (SS) dry eye, refractory to standard therapy, in comparison with patients treated with artificial tears. We focused on the effect of APL on cornea morphology with the in vivo confocal microscopy (IVCM). Methods. Patients were assigned to two groups: group A used autologous platelet lysate QID, and group B used preservative-free artificial tears QID, for 90 days. Ophthalmological assessments included ocular surface disease index (OSDI), best corrected visual acuity (BCVA), Schirmer test, fluorescein score, and breakup time (BUT). A subgroup of patients in group A underwent IVCM: corneal basal epithelium, subbasal nerves, Langerhans cells, anterior stroma activated keratocytes, and reflectivity were evaluated. Results. 60 eyes of 30 patients were enrolled; in group A (n = 20 patients) mean OSDI, fluorescein score, and BUT showed significant improvement compared with group B (n = 10 patients). The IVCM showed a significant increase in basal epithelium cells density and subbasal nerve plexus density and number and a decrease in Langerhans cells density (p < 0.05). Conclusion. APL was found effective in the treatment of SS dry eye. IVCM seems to be a useful tool to visualize cornea morphologic modifications. PMID:27200376

  6. The Effect of Autologous Platelet Lysate Eye Drops: An In Vivo Confocal Microscopy Study

    Directory of Open Access Journals (Sweden)

    Antonio M. Fea

    2016-01-01

    Full Text Available Purpose. To determine the effectiveness of autologous platelet lysate (APL eye drops in patients with primary Sjögren syndrome (SS dry eye, refractory to standard therapy, in comparison with patients treated with artificial tears. We focused on the effect of APL on cornea morphology with the in vivo confocal microscopy (IVCM. Methods. Patients were assigned to two groups: group A used autologous platelet lysate QID, and group B used preservative-free artificial tears QID, for 90 days. Ophthalmological assessments included ocular surface disease index (OSDI, best corrected visual acuity (BCVA, Schirmer test, fluorescein score, and breakup time (BUT. A subgroup of patients in group A underwent IVCM: corneal basal epithelium, subbasal nerves, Langerhans cells, anterior stroma activated keratocytes, and reflectivity were evaluated. Results. 60 eyes of 30 patients were enrolled; in group A (n=20 patients mean OSDI, fluorescein score, and BUT showed significant improvement compared with group B (n=10 patients. The IVCM showed a significant increase in basal epithelium cells density and subbasal nerve plexus density and number and a decrease in Langerhans cells density (p<0.05. Conclusion. APL was found effective in the treatment of SS dry eye. IVCM seems to be a useful tool to visualize cornea morphologic modifications.

  7. Eye-Movement Patterns of Readers with Down Syndrome during Sentence-Processing: An Exploratory Study

    Science.gov (United States)

    Frenck-Mestre, Cheryl; Zardan, Nathalie; Colas, Annie; Ghio, Alain

    2010-01-01

    Eye movements were examined to determine how readers with Down syndrome process sentences online. Participants were 9 individuals with Down syndrome ranging in reading level from Grades 1 to 3 and a reading-level-matched control group. For syntactically simple sentences, the pattern of reading times was similar for the two groups, with longer…

  8. Prevalence of age-related maculopathy in older Europeans: The European Eye Study (EUREYE)

    NARCIS (Netherlands)

    C. Augood (Cristina); J.R. Vingerling (Hans); P.T.V.M. de Jong (Paulus); U. Chakravarthy (Usha); J.H. Seland (Johan ); G. Soubrane; L. Tomazzoli (Laura); F. Topouzis (Fotis); G.C. Bentham (Graham ); M. Rahu; J. Vioque (Jesus); I.S. Young (Ian ); A.E. Fletcher (Astrid E.)

    2006-01-01

    textabstractObjective: To estimate the prevalence of age-related maculopathy in an older population from 7 European countries. Methods: Randomly sampled people 65 years and older were invited to an eye examination in centers across 7 European countries (Norway, Estonia, United Kingdom, France, Italy

  9. Structural brain MRI studies in eye diseases : are they clinically relevant? A review of current findings

    NARCIS (Netherlands)

    Prins, Doety; Hanekamp, Sandra; Cornelissen, Frans W.

    2016-01-01

    Many eye diseases reduce visual acuity or are associated with visual field defects. Because of the well-defined retinotopic organization of the connections of the visual pathways, this may affect specific parts of the visual pathways and cortex, as a result of either deprivation or transsynaptic deg

  10. Unilateral Amblyopia Affects Two Eyes: Fellow Eye Deficits in Amblyopia.

    Science.gov (United States)

    Meier, Kimberly; Giaschi, Deborah

    2017-03-01

    Unilateral amblyopia is a visual disorder that arises after selective disruption of visual input to one eye during critical periods of development. In the clinic, amblyopia is understood as poor visual acuity in an eye that was deprived of pattern vision early in life. By its nature, however, amblyopia has an adverse effect on the development of a binocular visual system and the interactions between signals from two eyes. Visual functions aside from visual acuity are impacted, and many studies have indicated compromised sensitivity in the fellow eye even though it demonstrates normal visual acuity. While these fellow eye deficits have been noted, no overarching theory has been proposed to describe why and under what conditions the fellow eye is impacted by amblyopia. Here, we consider four explanations that may account for decreased fellow eye sensitivity: the fellow eye is adversely impacted by treatment for amblyopia; the maturation of the fellow eye is delayed by amblyopia; fellow eye sensitivity is impacted for visual functions that rely on binocular cortex; and fellow eye deficits reflect an adaptive mechanism that works to equalize the sensitivity of the two eyes. To evaluate these ideas, we describe five visual functions that are commonly reported to be deficient in the amblyopic eye (hyperacuity, contrast sensitivity, spatial integration, global motion, and motion-defined form), and unify the current evidence for fellow eye deficits. Further research targeted at exploring fellow eye deficits in amblyopia will provide us with a broader understanding of normal visual development and how amblyopia impacts the developing visual system.

  11. The Study of Retinal Nerve Fiber Layer Thickness of Normal Eyes Using Scanning Laser Polarimetry

    Institute of Scientific and Technical Information of China (English)

    Xing Liu; Jingjing Huang; Jian Ge; Yunlan Ling; Xiaoping Zheng

    2006-01-01

    Purpoe: To evaluate retinal nerve fiber layer (RNFL) thickness measurements in local normal Chinese subjects of different age groups and analyse the correlation of RNFL thickness with age using scanning laser polarimetry (SLP, GDxVCC). To assess the reproducibility of RNFL thickness measurement with GDxVCC.Methods: The RNFL thickness of 67 normal subjects (123 eyes) were measured by GDxVCC. The average TSNIT parameters were calculated. The differences of RNFL thickness between sex, right and left eyes, superior and inferior were compared. The relationship between RNFL thickness and age was analyzed with correlation analysis and linear regression analysis. The intraclass correlation coefficients (ICC) of three images in every eye were calculated.Results: The average peripapillary RNFL thickness at the superior, inferior and whole ellipse regions in 123 eyes of 67 normal subjects were (70.30±6.76)μm, (67.35±6.77) μm and (56.87±4.53) μm, respectively. The average TNSIT standard deviation was 23.68±4.61 and the average inter-eye symmetric value was 0.86±0.11. There were significant difference of RNFL thickness between superior and inferior (t=4.952,P <0.001 ). There were significant difference of inferior RNFL thickness and TNSIT standard deviation between right and left eyes (P=0.005 and 0.002),while not significant difference of superior RNFL thickness and whole mean RNFL thickness between right and left eye (P=0.086 and 0.529). There was no significant difference in TSNIT parameters between different genders. There was a slight negative correlation average RNFL thickness in superior sector with age (decreased approximately 0.15 microns per year,P=0.047) in the subjects aged below 60 years old. The ICC values of RNFL thickness were >0.8 in superior, inferior and global.Conclusions: The RNFL thickness can be measured accurately by GDxVCC and the reproducibility of RNFL thickness measurement by GDxVCC is good. There was a slight negative correlation between

  12. Color vision deficiency in a middle-aged population: the Shahroud Eye Study.

    Science.gov (United States)

    Jafarzadehpur, Ebrahim; Hashemi, Hassan; Emamian, Mohammad Hassan; Khabazkhoob, Mehdi; Mehravaran, Shiva; Shariati, Mohammad; Fotouhi, Akbar

    2014-10-01

    The aim of this study was to determine the prevalence of color vision defects in the middle-age population of Shahroud, Iran. We selected 6,311 people from the 40- to 64-year-old population through random cluster sampling. Color vision testing was performed with the Farnsworth D-15. Cases with similar and symmetric results in both eyes were classified as hereditary, and those with asymmetric results were considered acquired. Cases that did not conform to standard patterns were classified as unknown category. Of 5,190 respondents (response rate 82.2 %), 5,102 participants underwent the color vision test. Of these, 14.7 % (95 % confidence interval 13.7-15.6) had some type of color vision deficiency. Of the 2,157 male participants, 6.2 % were hereditary and 10.2 % were acquired and of the 2,945 female participants, 3.1 % were hereditary and 10 % were acquired. Hereditary color deficiencies were mostly of the deutan form (63.8 %), and acquired deficiencies were mostly tritan (66.1 %). The prevalence of hereditary and acquired color vision deficiency, as well as different types of red-green and blue-yellow color vision defects significantly increased with age (p color vision defects among the middle-aged population of Shahroud was significantly different from that seen in the younger population. This could be due to changes associated with age, gender, medical and ocular conditions, and differences in race and environment. Thus, results of previous examinations and the overall health status should be considered before making any judgment about the status of color vision in middle-aged people.

  13. Observing Third-Party Attentional Relationships Affects Infants' Gaze Following: An Eye-Tracking Study

    Science.gov (United States)

    Meng, Xianwei; Uto, Yusuke; Hashiya, Kazuhide

    2017-01-01

    Not only responding to direct social actions toward themselves, infants also pay attention to relevant information from third-party interactions. However, it is unclear whether and how infants recognize the structure of these interactions. The current study aimed to investigate how infants' observation of third-party attentional relationships influence their subsequent gaze following. Nine-month-old, 1-year-old, and 1.5-year-old infants (N = 72, 37 girls) observed video clips in which a female actor gazed at one of two toys after she and her partner either silently faced each other (face-to-face condition) or looked in opposite directions (back-to-back condition). An eye tracker was used to record the infants' looking behavior (e.g., looking time, looking frequency). The analyses revealed that younger infants followed the actor's gaze toward the target object in both conditions, but this was not the case for the 1.5-year-old infants in the back-to-back condition. Furthermore, we found that infants' gaze following could be negatively predicted by their expectation of the partner's response to the actor's head turn (i.e., they shift their gaze toward the partner immediately after they realize that the actor's head will turn). These findings suggested that the sensitivity to the difference in knowledge and attentional states in the second year of human life could be extended to third-party interactions, even without any direct involvement in the situation. Additionally, a spontaneous concern with the epistemic gap between self and other, as well as between others, develops by this age. These processes might be considered part of the fundamental basis for human communication.

  14. Are smooth pursuit eye movements altered in chronic whiplash-associated disorders? A cross-sectional study

    DEFF Research Database (Denmark)

    Kongsted, Alice; Jørgensen, L V; Bendix, T

    2007-01-01

    To evaluate whether smooth pursuit eye movements differed between patients with long-lasting whiplash-associated disorders and controls when using a purely computerized method for the eye movement analysis.......To evaluate whether smooth pursuit eye movements differed between patients with long-lasting whiplash-associated disorders and controls when using a purely computerized method for the eye movement analysis....

  15. A clinical comparison between DisCoVisc and 2% hydroxypropylmethylcellulose in phacoemulsification: a fellow eye study

    OpenAIRE

    Espíndola, Rodrigo F.; Castro, Emerson F.S.; Marcony R. Santhiago; Newton Kara-Junior

    2012-01-01

    OBJECTIVE: This study sought to compare the effects and outcomes of two ophthalmic viscosurgical devices, 1.6% hyaluronic acid/4.0% chondroitin sulfate and 2.0% hydroxypropylmethylcellulose, during phacoemulsification. METHODS: This prospective, randomized clinical trial comprised 78 eyes (39 patients) that received phacoemulsification performed by the same surgeon using a standardized technique. Patients were randomly assigned to receive either 1.6% hyaluronic acid/4.0% chondroitin sulfate o...

  16. Pneumatic retinopexy: the evolution of case selection and surgical technique. A twelve-year study of 302 eyes.

    OpenAIRE

    Tornambe, P E

    1997-01-01

    BACKGROUND: Pneumatic retinopexy is an operation for reattaching the retina by injecting an expanding gas bubble and using laser and/or cryopexy. The procedure is controversial because the literature reports a variable initial success rate, sometimes less than conventional scleral buckling surgery. PR is done in an office setting and may be the most cost-effective means of retinal reattachment. OBJECTIVE: The goal of this study is to decide which eyes are most successfully treated with pneuma...

  17. Qualitative study on the awareness of eye health risks associated with type II diabetes in Lagos, Nigeria

    OpenAIRE

    Umaefulam, Valerie Onyinyechi

    2015-01-01

    Introduction: Diabetes mellitus is a major public health problem and its burden is expected to increase in developing countries such as Nigeria. One of the most frequent complications of type II diabetes is diabetic retinopathy, and a major cause of blindness worldwide especially among adults. Objective: To determine the awareness of diabetes – related eye health risks and complications among type II diabetics in Lagos, Nigeria. Method: The study was carried out in Rhowil Medical Centre in La...

  18. Researching the cognitive validity of GEPT High-Intermediate and Advanced Reading: an eye tracking and stimulated recall study

    OpenAIRE

    2016-01-01

    It is important for any language test to establish its cognitive validity in order to ensure that the test elicits from test takers those cognitive processes which correspond to the processes which they would normally employ in the target real-life context (Weir 2005). This study investigates the cognitive validity of the GEPT Reading Test at two levels. High-intermediate (CEFR B2) and Advanced (CEFR C1), using innovative eye-tracking technology and detailed stimulated recall interviews and s...

  19. REPRESENTAÇÃO GRÁFICA DOS ELEMENTOS DO CLIMA: ESTUDO COMPARATIVO ENTRE MARINGÁ, PR E BOTUCATU, SP

    Directory of Open Access Journals (Sweden)

    Emerson Galvani

    2006-12-01

    Full Text Available Graph representation of variables have a dual propose: the first is related to time and space variations and the second to its didactic character. Climatic elements (air and soil temperatures, relative humidity, global solar radiation (diffuse and direct, radiation balance (short wave and long wave, wind (direction and velocity, atmospheric pressure, rain indices and others display a certain characteristic curve that represents place, time weather conditions of a given region throughout the days, months and years. The factors that differentiate one place from another, in climactic terms, is the variation amplitude of the atmospheric elements in time and space. For instance, the daily curve of solar radiation levels on the earth surface is identical for two places on different latitudes. The amplitude of maximum values and total energy integrated throughout the day and the year differentiate them. The aim of current research is the representation of curves of the main climate elements with instantaneous daily and seasonal variations of the climatic conditions in the cities of Botucatu SP and Maringá PR Brazil.

  20. Control of parasitic infections among school children in the peri-urban area of Botucatu, São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Regina Coeli Cunha Dórea

    1996-10-01

    Full Text Available Tide prevalence of intestinal parasitosis ivas investigated in a primaiy school located in Rubiâo Júnior, a peri-urban district of Botucatu, São Paulo slate, Brazil, in order to assess the effect of treatment and practical measures of prophylaxis in the control of parasitic infections among 7-to- 18-year-old school children of a low socio-economic status. The first series of parasitological examinations included 219 school children, ef which 123 (56.1 % were found to be infected with one or more parasite species. Eighty- four children canying pathogenic parasites were submitted to various anti-parasitic treatment schedules. We re-evaluated 15 (89 % students after 4 to 6 months post- chemotherapy. The results indicate that the combination of treatment with prophylactic measures has been successful in the control of parasitic infections, since reinfection rates were generally low ( 73-1 % in children infected with most parasite species. The reasons for the apparent failure in the control of infections caused by Hymenolepis nana and Strongyloides stercoralis are discussed.

  1. Influence on ocular surface after cataract surgery and effect of topical diquafosol on postoperative dry eye: a multicenter prospective randomized study

    Directory of Open Access Journals (Sweden)

    Miyake K

    2017-03-01

    Full Text Available Kensaku Miyake,1 Norihiko Yokoi2 On behalf of Dry Eye After Cataract Surgery Investigational Study Group (DASIS group 1Miyake Eye Hospital, Nagoya, 2Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan Purpose: To investigate influences of 3% diquafosol sodium ophthalmic solution (DQS on ocular surface after cataract surgery and effects on postoperative dry eye. Design: This study had two consecutive prospective study phases. The former was an observational study from before cataract surgery to 4 weeks after surgery and the latter was a randomized open-label study from 4 to 8 weeks after surgery. Methods: Subjects were 433 eyes of 433 patients undergoing cataract surgery with intraocular lens implantation. Dry eye examination of tear breakup time (BUT, corneal and conjunctival fluorescein staining scores, total subjective symptom score (12 symptoms, and Schirmer I test were conducted before surgery and 4 weeks after surgery. Patient demographics and these examination results were used to analyze risk factors to predict postoperative dry eye. In a randomized study, 154 eyes diagnosed with dry eye postoperatively were applied either DQS or artificial tears (AT six times daily for 4 weeks. The data of the examinations were compared. Results: At 4 weeks after surgery, BUT was shortened significantly (P=0.036, fluorescein staining score increased significantly (P=0.012, but total subjective symptom score was significantly improved (P<0.001. The majority of postoperative dry eye was shortened BUT type (53.1%. The dry eye prevalence after surgery decreased (55.7% compared with before surgery (69.7%. Females and the patient with dry eye symptoms before surgery had significant risk factors for postoperative dry eye. In a randomized study, BUT was significantly prolonged in the DQS group (P=0.015, but not in the AT group. Fluorescein staining score was significantly improved in both groups (P<0.001. Total subjective symptom

  2. Genetic mechanisms involved in the evolution of the cephalopod camera eye revealed by transcriptomic and developmental studies

    OpenAIRE

    Ogura Atsushi; Yoshida Masa-aki

    2011-01-01

    Abstract Background Coleoid cephalopods (squids and octopuses) have evolved a camera eye, the structure of which is very similar to that found in vertebrates and which is considered a classic example of convergent evolution. Other molluscs, however, possess mirror, pin-hole, or compound eyes, all of which differ from the camera eye in the degree of complexity of the eye structures and neurons participating in the visual circuit. Therefore, genes expressed in the cephalopod eye after divergenc...

  3. Association Between Serum 25-Hydroxyvitamin D Levels and Dry Eye in Korean Adults: A Study Based on Korean National Health and Nutrition Examination Survey, 2010–2011

    Science.gov (United States)

    Kim, Min Ji; Kim, Yun-Jin; Lee, Sang-Yeoup; Lee, Jeong-Gyu; Jeong, Dong-Wook; Kim, Yun Hee

    2017-01-01

    Background Dry eye is a common disease. Many patients continue to experience residual symptoms despite optimal treatment. Thus, new treatment options are required. The purpose of this study was to evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and dry eye. Methods This study was performed using data from the fifth Korean National Health and Nutrition Examination Survey, which is a cross-sectional study of the Korean population that was conducted from 2010 to 2011. We included adults aged >19 years who underwent ophthalmologic interviews and examinations. We excluded subjects who had comorbid conditions (rheumatoid arthritis, thyroid disease, chronic kidney disease, or depression) that are associated with dry eye. The subjects were divided into normal and dry eye groups. The dry eye group consisted of those who had clinically diagnosed dry eye syndrome or symptoms. Multiple logistic regression analysis was conducted to determine the association between serum 25(OH)D levels and dry eye. Results In the univariate model, the 25(OH)D levels were lower in the dry eye group than in the normal group (P=0.01). A significant association was found between severe vitamin D deficiency (<10 ng/mL) and dry eye (P=0.04). However, after multivariate adjustment, the statistical significance of the association disappeared (P-values= 0.49, vitamin D insufficiency; P=0.33, vitamin D deficiency; P=0.18, severe vitamin D deficiency). Conclusion Severe vitamin D deficiency was associated with dry eye in an unadjusted model, but the association was not statistically significant after adjustment. PMID:28360983

  4. Spreading of hemiretinal projections in the ipsilateral tectum following unilateral enucleation: a study of optic nerve regeneration in Xenopus with one compound eye.

    Science.gov (United States)

    Straznicky, C; Tay, D

    1981-02-01

    Right compound eyes were formed in Xenopus embryos at stages 32-33 by the fusion of two nasal (NN), two ventral (VV) or two temporal (TT) halves. Shortly after metamorphosis the optic nerve from the compound eye was sectioned and the left intact eye removed. The retinotectal projections from the compound eye to the contralateral and ipsilateral tecta were studied by [3H]proline autoradiography and electrophysiological mapping between 6 weeks and 5 months after the postmetamorphic surgery. The results showed that NN and VV eyes projected to the entire extent of both tecta. In contrast, optic fibre projection from TT eyes, although more extensive than the normal temporal hemiretinal projection, failed to cover the caudomedial portion of the tecta. The visuotectal projections in all three combinations corresponded to typical reduplicated maps to be expected from such compound eyes, where each of the hemiretinae projected across the contralateral and ipsilateral tecta in an overlapping fashion. The rapid expansion of the hemiretinal projections of the compound eyes in the ipsilateral tectum following the removal of the resident optic fibre projection suggests that tectal markers may be carried and deployed by the incoming optic fibres themselves.

  5. Ten-year cumulative incidence of diabetic retinopathy. The Beijing Eye Study 2001/2011.

    Directory of Open Access Journals (Sweden)

    Jie Xu

    Full Text Available To assess the cumulative 10-year incidence of diabetic retinopathy (DR and its associated factors in a population living in Greater Beijing.The population-based longitudinal Beijing Eye Study, which included 4439 subjects (age in 2001: 40+years in 2001, was repeated in 2011 with 2695 subjects participating (66.4% of the survivors. The study participants underwent a detailed ophthalmic examination. Fundus photographs were examined for the new development of DR.After excluding individuals with DR at baseline (n = 87 or no sufficient fundus photographs in 2011 (n = 6, the study included 2602 subjects with a mean age of 64.6±9.7 years (median: 64.0 years; range: 50 to 93 years. In the 10-year period, 109 subjects (39 men developed new DR with an incidence of 4.2% (95% confidence interval (CI: 3.45,5.03. In multiple logistic regression analysis, incident DR was significantly associated with higher HbA1c value (P<0.001; Odds Ratio (OR: 1.73; 95% Confidence Interval (CI: 1.35,2.21, longer duration of diabetes mellitus (P<0.001; OR: 1.16; 95% CI: 1.10,1.22, higher serum concentration of creatinine (P = 0.02; OR: 1.01; 95% CI: 1.002,1.022, lower educational level (P = 0.049; OR: 0.74; 95% CI: 0.55,0.99, higher estimated cerebrospinal fluid pressure (P = 0.038; OR: 1.10; 95% CI: 1.01,1.22, and shorter axial length (P<0.001; OR: 0.48; 95% CI: 0.33,0.71.The cumulative 10-year incidence (mean: 4.2% of DR in a North Chinese population was significantly associated with a higher HbA1c value, longer known duration of diabetes mellitus, higher estimated CSFP and shorter axial length (P<0.001. Shorter axial length (or hyperopia and, potentially, higher CSFP may be additional risk factors to be taken into account when counseling and treating patients with diabetes mellitus.

  6. The influences of working memory representations on long-range regression in text reading: An eye-tracking study

    Directory of Open Access Journals (Sweden)

    Teppei eTanaka

    2014-09-01

    Full Text Available The present study investigated the relationship between verbal and visuospatial working memory capacity and long-range regression (i.e., word relocation processes in reading. We analyzed eye movements during a whodunit task, in which readers were asked to answer a content question while original text was being presented. The eye movements were more efficient in relocating a target word when the target was at recency positions within the text than when it was at primacy positions. Furthermore, both verbal and visuospatial working memory capacity partly predicted the efficiency of the initial long-range regression. The results indicate that working memory representations have a strong influence at the first stage of long-range regression by driving the first saccade movement toward the correct target position, suggesting that there is a dynamic interaction between internal working memory representations and external actions during text reading.

  7. Selenium Preferentially Accumulates in the Eye Lens Following Embryonic Exposure: A Confocal X-ray Fluorescence Imaging Study

    Energy Technology Data Exchange (ETDEWEB)

    Choudhury, Sanjukta; Thomas, Jith; Sylvain, Nicole J.; Ponomarenko, Olena; Gordon, Robert A.; Heald, Steve M.; Janz, David M.; Krone, Patrick H.; Coulthard, Ian; George, Graham N.; Pickering, Ingrid J.

    2015-02-17

    Maternal transfer of elevated selenium (Se) to offspring is an important route of Se exposure for fish in the natural environment. However, there is a lack of information on the tissue specific spatial distribution and speciation of Se in the early developmental stages of fish, which provide important information about Se toxicokinetics. The effect of maternal transfer of Se was studied by feeding adult zebrafish a Se-elevated or a control diet followed by collection of larvae from both groups. Novel confocal synchrotron-based techniques were used to investigate Se within intact preserved larvae. Confocal X-ray fluorescence imaging was used to compare Se distributions within specific planes of an intact larva from each of the two groups. The elevated Se treatment showed substantially higher Se levels than the control; Se preferentially accumulated to highest levels in the eye lens, with lower levels in the retina, yolk and other tissues. Confocal X-ray absorption spectroscopy was used to determine that the speciation of Se within the eye lens of the intact larva was a selenomethionine-like species. Preferential accumulation of Se in the eye lens may suggest a direct cause-and-effect relationship between exposure to elevated Se and Se-induced ocular impairments reported previously. This study illustrates the effectiveness of confocal X-ray fluorescence methods for investigating trace element distribution and speciation in intact biological specimens

  8. Psychophysiological Responsivity to Script-Driven Imagery: An Exploratory Study of the Effects of Eye Movements on Public Speaking Flashforwards.

    Science.gov (United States)

    Kearns, Michelle; Engelhard, Iris M

    2015-01-01

    A principle characteristic of public speaking anxiety relates to intrusive mental images of potential future disasters. Previous research has found that the self-reported emotionality of such "flashforwards" can be reduced by a cognitively demanding, dual-task (e.g., making eye movements) performed whilst holding the mental image in-mind. The outcome measure in these earlier studies was participants' self-reported emotional intensity of the mental image. The current study (N = 34) explored whether an objective measure of emotionality would yield similar results in students with public speaking anxiety. A script-driven imagery procedure was used to measure psychophysiological responsivity to an audio script depicting a feared (public speaking) scenario before and after an eye movement intervention. Relative to the control condition (imagery only), those who made eye movements whilst holding a mental image of this scenario in-mind demonstrated a significant decrease in heart rate, which acted as a measure of emotionality. These findings add to a previous body of research demonstrating the beneficial qualities of dual-tasks and their potential for treatment of both past and future-oriented anxieties.

  9. STUDY OF CORRELATION AND SIGNIFICANCE OF BIOCHEMICAL PARAMETERS IN THE ASSESSMENT OF ACTIVE PHASE OF THYROID EYE DISEASE

    Directory of Open Access Journals (Sweden)

    Ashok Kumar P

    2016-08-01

    Full Text Available AIM Role of Interleukin-6 and HS-CRP Levels in the assessment of active thyroid eye disease. MATERIALS & METHODS A prospective observational study of 30 patients from the age group of 20-60 years with thyroid eye disease done at Regional Institute of Ophthalmology. All patients were subjected to detailed history, ocular examination, systemic examination, biochemical analysis and Imaging. Patients are categorised as mild, moderate and severe active disease based on clinical activity score. For the period of two years, patients are followed at regular periodic intervals according to the severity of disease and results were analysed. RESULTS Out of 30 patients studied, majority of the patients were females (60%, and 70% of the patients had bilateral disease. Among 30 patients, 83.33% in hyperthyroid state, 3.33% in Hypothyroid state, 13.33% in Euthyroid state (Table 3. Smoking being important risk factor in 30% among males. 50% of patients presented with mild disease, 30% with moderate disease, 0% with severe disease. IL-6, HS-CRP levels are increased only in patients with severe active disease (Table 6. Remission attained in all patients when treated earlier with steroids. CONCLUSION Identifying disease activity early and aggressive treatment with systemic steroids in active phase of moderate and severe disease has reduced the morbidity associated with disease. Correlation of IL-6, HS-CRP, TFT levels are significantly increased only in patients with active phase of severe thyroid eye disease but not significantly elevated in active phase of moderate disease. Another pitfall is IL-6 is an expensive ELISA based diagnosis. Thus, IL-6 & HS-CRP cannot be routinely used to screen patients with Thyroid eye disease.

  10. An Eye-tracking Study of Feature-based Choice in One-shot Games

    DEFF Research Database (Denmark)

    Devetag, Giovanna; Di Guida, Sibilla; Polonio, Luca

    2016-01-01

    for a subset of game outcomes. We analyze subjects’ eye movements while playing a series of two-person, 3x3 one-shot games in normal form. Games within each class differ by a set of descriptive features (i.e., features that can be changed without altering the game equilibrium properties). Data show...... with the highest average payoff" or "choose the strategy leading to an attractive and symmetric outcome" without (optimally) incorporating knowledge on the opponent’s behavior. Lookup patterns resulted being feature and game invariant, heterogeneous across subjects, but stable within subjects. Using a cluster...... analysis, we find correlations between eye-movements and choices; however, applying the Cognitive Hierarchy model to our data, we show that only some of the subjects present both information search patterns and choices compatible with a specific cognitive level. We also find a series of correlations...

  11. Hidden communicative competence: case study evidence using eye-tracking and video analysis.

    Science.gov (United States)

    Grayson, Andrew; Emerson, Anne; Howard-Jones, Patricia; O'Neil, Lynne

    2012-01-01

    A facilitated communication (FC) user with an autism spectrum disorder produced sophisticated texts by pointing, with physical support, to letters on a letterboard while their eyes were tracked and while their pointing movements were video recorded. This FC user has virtually no independent means of expression, and is held to have no literacy skills. The resulting data were subjected to a variety of analyses aimed at describing the relationship between the FC user's looking and pointing behaviours, in order to make inferences about the complex question of 'authorship'. The eye-tracking data present a challenge to traditional 'facilitator influence' accounts of authorship, and are consistent with the proposition that this FC user does indeed author the sophisticated texts that are attributed to him; he looks for longer at to-be-typed letters before typing them, and looks ahead to subsequent letters of words before the next letter of the word is typed.

  12. Neuroanatomical circuitry associated with exploratory eye movement in schizophrenia: a voxel-based morphometric study.

    Directory of Open Access Journals (Sweden)

    Linlin Qiu

    Full Text Available Schizophrenic patients present abnormalities in a variety of eye movement tasks. Exploratory eye movement (EEM dysfunction appears to be particularly specific to schizophrenia. However, the underlying mechanisms of EEM dysfunction in schizophrenia are not clearly understood. To assess the potential neuroanatomical substrates of EEM, we recorded EEM performance and conducted a voxel-based morphometric analysis of gray matter in 33 schizophrenic patients and 29 well matched healthy controls. In schizophrenic patients, decreased responsive search score (RSS and widespread gray matter density (GMD reductions were observed. Moreover, the RSS was positively correlated with GMD in distributed brain regions in schizophrenic patients. Furthermore, in schizophrenic patients, some brain regions with neuroanatomical deficits overlapped with some ones associated with RSS. These brain regions constituted an occipito-tempro-frontal circuitry involved in visual information processing and eye movement control, including the left calcarine cortex [Brodmann area (BA 17], the left cuneus (BA 18, the left superior occipital cortex (BA 18/19, the left superior frontal gyrus (BA 6, the left cerebellum, the right lingual cortex (BA 17/18, the right middle occipital cortex (BA19, the right inferior temporal cortex (BA 37, the right dorsolateral prefrontal cortex (BA 46 and bilateral precentral gyri (BA 6 extending to the frontal eye fields (FEF, BA 8. To our knowledge, we firstly reported empirical evidence that gray matter loss in the occipito-tempro-frontal neuroanatomical circuitry of visual processing system was associated with EEM performance in schizophrenia, which may be helpful for the future effort to reveal the underlying neural mechanisms for EEM disturbances in schizophrenia.

  13. Toxicological study of the molluscicidal latex of Euphorbia splendens: irritant action on skin and eye

    Directory of Open Access Journals (Sweden)

    J. C. B. R. Freitas

    1991-01-01

    Full Text Available Aqueous solutions of the molluscicidal latex of Euphorbia splendens are irritant to the rabbit eye in concentrations higher than 0.35% and to the rabbit skin in concentrations higher than 0.5%. Although this irritant potential does not proclude its use as a molluscicide, special precautions are recommended for hanbdling and application of the product and the hazard of skin tumor-promoting potencial should be carefully investigated before its use for schistosomiasis vector control.

  14. Rett syndrome: basic features of visual processing-a pilot study of eye-tracking.

    Science.gov (United States)

    Djukic, Aleksandra; Valicenti McDermott, Maria; Mavrommatis, Kathleen; Martins, Cristina L

    2012-07-01

    Consistently observed "strong eye gaze" has not been validated as a means of communication in girls with Rett syndrome, ubiquitously affected by apraxia, unable to reply either verbally or manually to questions during formal psychologic assessment. We examined nonverbal cognitive abilities and basic features of visual processing (visual discrimination attention/memory) by analyzing patterns of visual fixation in 44 girls with Rett syndrome, compared with typical control subjects. To determine features of visual fixation patterns, multiple pictures (with the location of the salient and presence/absence of novel stimuli as variables) were presented on the screen of a TS120 eye-tracker. Of the 44, 35 (80%) calibrated and exhibited meaningful patterns of visual fixation. They looked longer at salient stimuli (cartoon, 2.8 ± 2 seconds S.D., vs shape, 0.9 ± 1.2 seconds S.D.; P = 0.02), regardless of their position on the screen. They recognized novel stimuli, decreasing the fixation time on the central image when another image appeared on the periphery of the slide (2.7 ± 1 seconds S.D. vs 1.8 ± 1 seconds S.D., P = 0.002). Eye-tracking provides a feasible method for cognitive assessment and new insights into the "hidden" abilities of individuals with Rett syndrome.

  15. Qualidade de vida em urticária crônica: inquérito em ambulatório público universitário, Botucatu (Brasil Quality of life in chronic urticaria: a survey at a public university outpatient clinic, Botucatu (Brazil

    Directory of Open Access Journals (Sweden)

    Maria Regina Cavariani Silvares

    2011-10-01

    Full Text Available OBJETIVO: Avaliar o impacto da urticária crônica na qualidade de vida dos pacientes de ambulatório universitário a partir do questionário DLQI (Dermatology Life Quality Index. MÉTODOS: Inquérito sobre o impacto na qualidade de vida infligido pela urticária crônica a partir do questionário DLQI validado para a língua portuguesa. Pacientes foram entrevistados durante suas consultas em ambulatório especializado, entre maio de 2009 e maio de 2010, em serviço público brasileiro (Botucatu-SP. Os escores do DLQI foram analisados segundo subgrupos: idade, gênero, escolaridade, tempo de doença e presença de angioedema. RESULTADOS: Foram entrevistados 100 pacientes com urticária crônica. Predominou o gênero feminino (86%, a idade média foi de 41,8 anos, duração média da doença foi de seis anos e angioedema ocorreu em 82% dos pacientes. O escore médio do DLQI foi de 13,5, caracterizando grave impacto à qualidade de vida, superior a hanseníase, psoríase, eczema atópico e carcinoma basocelular. Presença de angioedema se associou a maiores escores: 14,5 x 9,9 (p OBJECTIVE: To evaluate the impact of chronic urticaria on quality of life of outpatients through the university questionnaire Dermatology Life Quality Index (DLQI. METHODS: Survey of the impact on quality of life caused by chronic urticaria, using the DLQI questionnaire validated for the Portuguese language. Patients were interviewed during visits to a specialized outpatient clinic between May 2009 and May 2010 at a Brazilian public service (Botucatu-SP. DLQI scores were analyzed according to the following subgroups: age, gender, education, disease duration, and presence of angioedema. RESULTS: We interviewed 100 patients with chronic urticaria. There was a female predominance (86%, mean age 41.8 years, mean disease duration of 6 years, and angioedema occurrence in 82% of patients. The mean DLQI score was 13.5, characterized by serious impact on quality of life, higher

  16. Factors associated with myopia in school children in China: the Beijing childhood eye study.

    Directory of Open Access Journals (Sweden)

    Qi Sheng You

    Full Text Available PURPOSE: To assess factors associated with myopia in school children in rural and urban parts of Greater Beijing. METHODS: The Beijing Pedriatic Eye Study was a population-based cross-sectional study, in which one school of each level (primary, junior high, senior high was randomly selected from nine randomly selected districts out of 18 districts of Greater Beijing. The children underwent non-cylcoplegic refractometry and their parents an interview. RESULTS: Of 16,771 eligible students, 15,066 (89.8% children (7,769 (51.6% girls participated, with 8,860 (58.8% participants living in the rural region. Mean age was 13.2±3.4 years (range:7-18 years. In multivariate analysis, prevalence of myopia (defined as ≤-1.00 diopters was associated with higher age (Odds ratio(OR:1.37; 95% confidence interval(CI:1.35,1.39, female gender (OR:1.35;95%CI:1.25,1.47, key school type (OR:0.77;95%CI: 0.70,0.85, higher family income (OR:1.04;95%CI:1.01,1.07, parental myopia (OR:1.46;95%CI:1.40,1.53, dim reading illumination (OR:0.93;95%CI: 0.88,0.98, longer daily studying duration (OR:1.10;95%CI:1.06,1.15, shorter duration of watching television (or computer (OR:0.93;95%CI:0.89,0.97, higher self-reported protein intake (OR:0.94;95%CI:0.90,0.99, feeling well about life and status (OR:0.93;95%CI:0.89,0.98, and feeling tired or dizzy (OR:0.94;95%CI:0.91,0.97. Prevalence of high myopia (defined as ≤-6.00 diopters was associated with higher age (OR:1.43;95%CI:1.38, 1.48, key school type (OR:0.61;95%CI:0.49,0.74, family income (OR:1.07;95%CI:1.02,1.13, parental myopia (OR:1.65;95%CI:1.54,1.76, dim reading illumination (OR:0.86;95%CI:0.77,0.96, less rest during studying (OR:1.18;95%CI:1.10,1.27, feeling well about life and studying (OR:0.88;95%CI: 0.81,0.96 and feeling dizzy or tired (OR:0.93;95%CI:0.87,0.99. Prevalence of high myopia (defined as ≤-8.00 diopters was significantly associated with higher age (OR:1.39;95%CI:1.31,1.48;, key school type (OR:0.61;95%CI:0

  17. Crescimento, produção e qualidade de frutos da bananeira 'Figo cinza', em Botucatu-SP Growth, yield and quality of 'Figo cinza' banana fruits in Botucatu-SP

    Directory of Open Access Journals (Sweden)

    Dayana Portes Ramos

    2009-09-01

    Full Text Available A bananeira Figo Cinza é uma cultivar do grupo ABB, subgrupo Figo, que apresenta tolerância ao mal-do-panamá e às sigatokas amarela e negra, demonstrando ser uma cultivar interessante para programas de melhoramento genético. Devido a isso, o presente trabalho teve como objetivo avaliar características do 1º ciclo da planta, como o crescimento, produção e atributos físico-químicos dos frutos dessa cultivar, no município de Botucatu-SP. Foram avaliadas as seguintes características de crescimento: altura de plantas, circunferência do pseudocaule e número de folhas, medidas na época de emissão da inflorescência; número de dias entre o plantio e o florescimento, número de dias entre o florescimento e a colheita, e número de dias do plantio à colheita. Também foram mensuradas as seguintes características de produção: peso do cacho, número de frutos, peso médio dos frutos, número de pencas e produtividade; na 2ª penca foram avaliados peso, número, comprimento e diâmetro dos frutos. Os atributos fisico-químicos analisados foram: textura, pH, acidez titulável, sólidos solúveis, açúcares totais, amido e teor de potássio. Foi utilizado o método das estatísticas descritivas para a caracterização da cultivar, através dos cálculos das médias. Os resultados mostraram que 'Figo Cinza' apresentou porte médio (2,9 m, ciclo de 420 dias, produtividade média de 12,74 t ha -1 e frutos com baixa acidez (0,06%.'Figo Cinza' is a cultivar of the genomic group ABB, Figo subgroup, which provides tolerance to Panama and Sigatoka diseases that may be useful in genetic breeding programs. Then, this work aimed to evaluate the plants growth, production and also the physical and chemical characteristics of the fruits from this cultivar in Botucatu city, São Paulo state, Brazil. Some growth characteristics were evaluated such as: plant height, the pseudostem circumference, number of leaves, number of days between planting and

  18. Avaliação de genótipos de bananeira em Botucatu-SP Evaluation of banana genotypes in Botucatu, state of São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Dayana Portes Ramos

    2009-12-01

    Full Text Available O objetivo do trabalho foi avaliar o crescimento e a produção de genótipos de 3 grupos genômicos de bananeira: 'Nanicão-IAC-2001', 'Grande Naine', 'Caipira' e 'Nam' (AAA; 'maçã', 'Thap maeo', 'Prata-Anã' e 'Prata-Zulu' (AAB; 'FHIA 01', 'FHIA 18', 'Prata-Graúda' e 'maçã Tropical' (AAAB, em Botucatu-SP. Foram avaliadas as seguintes características de crescimento: altura de plantas, circunferência do pseudocaule, número de folhas, número de dias entre o plantio e o florescimento, entre o florescimento e a colheita e do plantio à colheita. As características de produção avaliadas foram: peso do cacho, número de pencas, número de frutos, peso médio dos frutos, produtividade; peso, número, comprimento e diâmetro de frutos da 2ª penca. os resultados mostraram que, no grupo AAA, 'Nanicão' apresentou boas características de crescimento e produção, no entanto 'Grande Naine' apresentou maiores valores produtivos. 'Nam' apresentou menor porte e ciclo, porém baixos valores produtivos. No grupo AAB, 'Prata-Zulu' apresentou maior circunferência do pseudocaule, boas características produtivas, porém ciclo longo e porte maior. 'Thap maeo' destacou-se por apresentar boas características de produção. 'Prata-Anã' apresentou porte reduzido, menor ciclo, porém não apresentou bom desempenho produtivo. 'FHIA 01', no grupo AAAB, apresentou maiores valores na maioria das características avaliadas. Pode concluir-se que 'Grande Naine' se destacou no grupo AAA, 'Thap maeo' no grupo AAB e 'FHIA 01' no grupo AAAB.The purpose of this research was to assess the plants growth and production of genotypes of 4 genomic groups of banana: 'Nanicão-iAC-2001', 'Grande Naine', 'Caipira' and 'Nam' (AAA; 'maçã', 'Thap maeo', 'PrataAnã'and 'Prata Zulu'(AAB; 'FHIA01', 'FHIA18', 'Prata Graúda'and 'maçã Tropical' (AAAB, in Botucatu, state of São Paulo, Brazil. Some growth characteristics were evaluated such as: plant height, the pseudostem

  19. Your Eyes

    Science.gov (United States)

    ... people you know — like your grandparents — probably wear glasses. To the Brain! Think of the optic nerve as the great messenger in the back of your eye. The rods and cones of the retina change the colors and shapes you see into millions of nerve ...

  20. A thermographic study on eyes affected by Age-related Macular Degeneration: Comparison among various forms of the pathology and analysis of risk factors

    Science.gov (United States)

    Matteoli, Sara; Finocchio, Lucia; Biagini, Ilaria; Giacomelli, Giovanni; Sodi, Andrea; Corvi, Andrea; Virgili, Gianni; Rizzo, Stanislao

    2016-05-01

    The aims of this study are to investigate (1) the ocular thermographic profiles in eyes affected by Age related Macular Degeneration (AMD) and age-matched controls to detect possible hemodynamic abnormalities that could be involved in the pathogenesis of the disease, (2) whether any risk factors associated with the disease could affect the development of a form of AMD rather than another. Thirty-four eyes with Age-Related Maculopathy (ARM), 41 eyes with dry AMD, 60 eyes affected by wet AMD, and 74 eyes with fibrotic AMD were included in the study. The control group consisted of 48 healthy eyes. Exclusion criteria were represented by any other ocular diseases other than AMD, tear film abnormalities, systemic cardiovascular abnormalities, systemic diseases and a body temperature higher than 37.5 °C. A total of 210 eyes without pupil dilation were investigated by infrared thermography (FLIR A320). The Ocular Surface Temperature (OST) of five ocular areas was calculated by means of an image processing technique from the infrared images. Two-sample t-test, one-way ANOVA test and multivariate analysis were used for statistical analyses. ANOVA analyses showed no significant differences among AMD groups (P-value > 0.05), however, OST in AMD patients was significantly lower than in controls (P-value wet AMD instead of dry AMD. Infrared thermography may be a helpful, non-invasive and not time-consuming method to be used in the management of patients with this common degenerative maculopathy.

  1. Development of an Accommodation-Dependent Eye Model and Studying the Effects of Accommodation on Electron and Proton Dose Conversion Coefficients

    Directory of Open Access Journals (Sweden)

    Alireza Vejdani-Noghreiyan

    2016-06-01

    Full Text Available Introduction International Commission on Radiological Protection (ICRP has provided a comprehensive discussion on threshold dose for radiation-induced cataract in ICRP publication 116. Accordingly, various parts of the eye lens have different radio-sensitivities. Recently, some studies have been performed to develop a realistic eye model with the aim of providing accurate estimation of fluence-to-dose conversion coefficients for different parts of the eye. However, the effect of accommodation, which changes the lens shape and pupil size, on dose conversion coefficients has not been considered yet. In this study, we purport to develop an accommodation-dependent eye model and to study the effects of accommodation on the electron and proton fluence-to-dose conversion coefficients. Materials and Methods Herein, a modified eye model was developed by considering the effects of accommodation on the lens shape and pupil size. In addition, MCNPX 2.6 Monte Carlo transport code was used to calculate the effects of  eye lens accommodation on electron and proton fluence-to-dose conversion coefficients. Results Calculation of dose conversion coefficients demonstrated that the accommodation causes up to 40% discrepancy for fluence-to-dose conversion coefficients of electrons in the range of 600 to 800 keV, which is due to the change of eye lens shape during the accommodation of the eye. Conclusion Since the accommodation of the eye change the lens shape and pupil size, it has considerable effect on fluence-to-dose conversion coefficients of electrons at some ranges of incident particle energies that should be considered in simulation. However, the fluctuation of dose conversion coefficients of protons is negligible.

  2. Development of online use of theory of mind during adolescence: An eye-tracking study.

    Science.gov (United States)

    Symeonidou, Irene; Dumontheil, Iroise; Chow, Wing-Yee; Breheny, Richard

    2016-09-01

    We investigated the development of theory of mind use through eye-tracking in children (9-13years old, n=14), adolescents (14-17.9years old, n=28), and adults (19-29years old, n=23). Participants performed a computerized task in which a director instructed them to move objects placed on a set of shelves. Some of the objects were blocked off from the director's point of view; therefore, participants needed to take into consideration the director's ignorance of these objects when following the director's instructions. In a control condition, participants performed the same task in the absence of the director and were told that the instructions would refer only to items in slots without a back panel, controlling for general cognitive demands of the task. Participants also performed two inhibitory control tasks. We replicated previous findings, namely that in the director-present condition, but not in the control condition, children and adolescents made more errors than adults, suggesting that theory of mind use improves between adolescence and adulthood. Inhibitory control partly accounted for errors on the director task, indicating that it is a factor of developmental change in perspective taking. Eye-tracking data revealed early eye gaze differences between trials where the director's perspective was taken into account and those where it was not. Once differences in accuracy rates were considered, all age groups engaged in the same kind of online processing during perspective taking but differed in how often they engaged in perspective taking. When perspective is correctly taken, all age groups' gaze data point to an early influence of perspective information.

  3. Eye Movement Disorders

    Science.gov (United States)

    ... work properly. There are many kinds of eye movement disorders. Two common ones are Strabismus - a disorder in ... the eyes, sometimes called "dancing eyes" Some eye movement disorders are present at birth. Others develop over time ...

  4. Why Do Eyes Water?

    Science.gov (United States)

    ... Happens in the Operating Room? Why Do Eyes Water? KidsHealth > For Kids > Why Do Eyes Water? A ... out of your nose. continue Why Do Eyes Water? Eyes water for lots of different reasons besides ...

  5. Recommended Sports Eye Protectors

    Science.gov (United States)

    ... Financial Assistance Information Vision Screening and Eye Exams Zika Virus and Vision Eye Problems Eye Problems Amblyopia ( ... Eye Health Report Reports and External Resources The Cost of Vision Problems The Future of Vision Vision ...

  6. Eye Safety at Home

    Science.gov (United States)

    ... Financial Assistance Information Vision Screening and Eye Exams Zika Virus and Vision Eye Problems Eye Problems Amblyopia ( ... Eye Health Report Reports and External Resources The Cost of Vision Problems The Future of Vision Vision ...

  7. Eye Safety at Work

    Science.gov (United States)

    ... Financial Assistance Information Vision Screening and Eye Exams Zika Virus and Vision Eye Problems Eye Problems Amblyopia ( ... Eye Health Report Reports and External Resources The Cost of Vision Problems The Future of Vision Vision ...

  8. Eye muscle repair - discharge

    Science.gov (United States)

    ... Lazy eye repair - discharge; Strabismus repair - discharge; Extraocular muscle surgery - discharge ... You or your child had eye muscle repair surgery to correct eye muscle ... term for crossed eyes is strabismus. Children most often ...

  9. Conjunctivitis (Pink Eye)

    Science.gov (United States)

    ... that can be embedded on web pages. Conjunctivitis (Pink Eye) One-Page Overview Pink, itchy eyes? Conjunctivitis – ... protect yourself from getting and spreading pink eye . Pink Eye: What To Do Discusses causes and treatment, ...

  10. About the Eye

    Medline Plus

    Full Text Available ... eye behind the iris that helps to focus light on the retina. It allows the eye to ... of the eye. It regulates the amount of light entering the eye through the pupil. Pupil (PYOO- ...

  11. Reading during the composition of multi-sentence texts: an eye-movement study.

    Science.gov (United States)

    Torrance, Mark; Johansson, Roger; Johansson, Victoria; Wengelin, Åsa

    2016-09-01

    Writers composing multi-sentence texts have immediate access to a visual representation of what they have written. Little is known about the detail of writers' eye movements within this text during production. We describe two experiments in which competent adult writers' eye movements were tracked while performing short expository writing tasks. These are contrasted with conditions in which participants read and evaluated researcher-provided texts. Writers spent a mean of around 13 % of their time looking back into their text. Initiation of these look-back sequences was strongly predicted by linguistically important boundaries in their ongoing production (e.g., writers were much more likely to look back immediately prior to starting a new sentence). 36 % of look-back sequences were associated with sustained reading and the remainder with less patterned forward and backward saccades between words ("hopping"). Fixation and gaze durations and the presence of word-length effects suggested lexical processing of fixated words in both reading and hopping sequences. Word frequency effects were not present when writers read their own text. Findings demonstrate the technical possibility and potential value of examining writers' fixations within their just-written text. We suggest that these fixations do not serve solely, or even primarily, in monitoring for error, but play an important role in planning ongoing production.

  12. Stereo-PIV study of flow inside an eye under cataract surgery

    Science.gov (United States)

    Sakakibara, Jun; Yamashita, Masaki; Kobayashi, Tatsuya; Kaji, Yuichi; Oshika, Tetsuro

    2012-04-01

    We measured velocity distributions in the anterior chamber of porcine eyes under simulated cataract surgery using stereoscopic particle image velocimetry (stereo-PIV). The surface of the cornea was detected based on the images of laser-induced fluorescent light emitted from fluorescent dye solution introduced in a posterior chamber. A coaxial phacoemulsification procedure was simulated with standard size (standard coaxial phacoemulsification) and smaller (micro coaxial phacoemulsification) surgical instruments. In both cases, an asymmetric flow rate of irrigation was observed, although both irrigation ports had the same dimensions prior to insertion into the eye. In cases where the tip of the handpiece was placed farther away from the top of the cornea, i.e., closer to the crystalline lens, direct impingement of irrigation flow onto the cornea surface was avoided and the flow turned back toward the handpiece along the surface of the corneal endothelium. Viscous shear stress on the corneal endothelium was computed based on the measured mean velocity distribution. The maximum shear stress for most cases exceeded 0.1 Pa, which is comparable to the shear stress that caused detachment of the corneal endothelial cells reported by Kaji et al. in Cornea 24:S55-S58, (2005). When direct impingement of the irrigation flow was avoided, the shear stress was reduced considerably.

  13. Social attention in ASD: A review and meta-analysis of eye-tracking studies.

    Science.gov (United States)

    Chita-Tegmark, Meia

    2016-01-01

    Determining whether social attention is reduced in Autism Spectrum Disorder (ASD) and what factors influence social attention is important to our theoretical understanding of developmental trajectories of ASD and to designing targeted interventions for ASD. This meta-analysis examines data from 38 articles that used eye-tracking methods to compare individuals with ASD and TD controls. In this paper, the impact of eight factors on the size of the effect for the difference in social attention between these two groups are evaluated: age, non-verbal IQ matching, verbal IQ matching, motion, social content, ecological validity, audio input and attention bids. Results show that individuals with ASD spend less time attending to social stimuli than typically developing (TD) controls, with a mean effect size of 0.55. Social attention in ASD was most impacted when stimuli had a high social content (showed more than one person). This meta-analysis provides an opportunity to survey the eye-tracking research on social attention in ASD and to outline potential future research directions, more specifically research of social attention in the context of stimuli with high social content.

  14. Elasticity of the eye's crystalline lens: A Brillouin light scattering study.

    Science.gov (United States)

    Bailey, S.; Gump, J.; Sooryakumar, R.; Jayaprakash, C.; Venkiteshwar, M. S.; Bullimore, M.; Twa, M.

    2009-03-01

    Focusing the eye on a near object results in an increase in its optical power brought about by contraction of the ciliary muscles and an increase in the lens surface curvature. Distant vision occurs when the muscular force flattens the lens. Central to the ability of the lens to alter shape are its mechanical properties. Thus, given that hardening of the lens would impede deformation and reduce its ability to undergo the changes required for accommodation, a noninvasive approach to measure the elastic properties of the lens is valuable. We present results of Brillouin scattering from bovine and human lenses (from the organ donor program at The Ohio State University) that measure their high frequency acoustic response. These measurements are conducted with a few milli-watts of laser power and, in the case of bovine lenses, from entire intact eye globes, allow the stiffness of the lens to be mapped across its cross-section. The results will be compared to values of the shear- and bulk-moduli determined from other techniques and the implications of differences in these moduli discussed.

  15. Influence on ocular surface after cataract surgery and effect of topical diquafosol on postoperative dry eye: a multicenter prospective randomized study

    Science.gov (United States)

    Miyake, Kensaku; Yokoi, Norihiko

    2017-01-01

    Purpose To investigate influences of 3% diquafosol sodium ophthalmic solution (DQS) on ocular surface after cataract surgery and effects on postoperative dry eye. Design This study had two consecutive prospective study phases. The former was an observational study from before cataract surgery to 4 weeks after surgery and the latter was a randomized open-label study from 4 to 8 weeks after surgery. Methods Subjects were 433 eyes of 433 patients undergoing cataract surgery with intraocular lens implantation. Dry eye examination of tear breakup time (BUT), corneal and conjunctival fluorescein staining scores, total subjective symptom score (12 symptoms), and Schirmer I test were conducted before surgery and 4 weeks after surgery. Patient demographics and these examination results were used to analyze risk factors to predict postoperative dry eye. In a randomized study, 154 eyes diagnosed with dry eye postoperatively were applied either DQS or artificial tears (AT) six times daily for 4 weeks. The data of the examinations were compared. Results At 4 weeks after surgery, BUT was shortened significantly (P=0.036), fluorescein staining score increased significantly (P=0.012), but total subjective symptom score was significantly improved (Pscore was significantly improved in both groups (Pscore was significantly decreased in the AT group (Pfilm stability and ocular surface, and DQS has a capability to improve them. PMID:28360509

  16. PREVALÊNCIA DE ENDOPARASITAS EM AMOSTRAS FECAIS DE AVES SILVESTRES E EXÓTICAS EXAMINADAS NO LABORATÓRIO DE ORNITOPATOLOGIA E NO LABORATÓRIO DE ENFERMIDADES PARASITÁRIAS DA FMVZ-UNESP/BOTUCATU-SP PREVALENCE OF ENDOPARASITES IN FECAL SAMPLES OF EXOTIC AND WILD BIRDS EXAMINED IN THE LABORATORY OF ORNITOPATOLOGY AND LABORATORY OF PARASITICS DISEASES OF THE FMVZ – UNESP/BOTUCATU, SP

    Directory of Open Access Journals (Sweden)

    Raimundo de Souza Lopes

    2009-04-01

    Full Text Available Dos vários problemas sanitários que afetam as aves, as enfermidades parasitárias estão entre as mais frequentes. Analisou-se no presente trabalho a prevalência de endoparasitas das 207 amostras fecais de aves silvestres e exóticas atendidas no Laboratório de Ornitopatologia e no Laboratório de Enfermidades Parasitárias do Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Universidade Estadual Paulista (FMVZ-UNESP, campus de Botucatu, SP. As amostras foram inicialmente analisadas através do exame direto a fresco e, após a constatação da presença de ovos, cistos ou oocistos nas fezes, as mesmas amostras foram submetidas à Técnica de Faust e ao Método de Willis.  No estudo encontraram-se ovos de três gêneros de nematoídes e cistos de quatro gêneros de protozoários em cinco de doze ordens aviárias, sendo Passeriformes a que apresentou o maior número de indivíduos parasitados.

    PALAVRAS-CHAVES: Aves, ornitopatologia, parasitologia. Among the various sanitary problems affecting birds, parasitic diseases are some of the most common ones. This study analyses the prevalence of endoparasites in 20 fecal samples of wild and exotic birds attended at the Ornitopathology and Parasitic Diseases Laboratories of the Veterinary Hospital, Faculty of Veterinary Medicine and Zootecnics, São Paulo State University (FMVZ-UNESP, campus Botucatu. After confirmation of eggs, cysts or oocysts through direct fecal test, Faust technique and Willis Method were performed on feces. Eggs of three genera of nematodes as well as cysts of four genera of protozoaries were found in five of 12 avian orders, with the order Passeriformes representing the most of the parasited individuals.

    KEY WORDS: Birds, ornitopathology, parasitology.

  17. Relationship between Refractive Error and Ocular Biomet-rics in Twin Children:the Guangzhou Twin Eye Study

    Institute of Scientific and Technical Information of China (English)

    Decai Wang; Bin Liu; Shengsong Huang; Wenyong Huang; Mingguang He

    2014-01-01

    Purpose:.A cross-sectional study was conducted to explore the relationship between refractive error and ocular biometrics in children from the Guangzhou twin eye study.Methods:.Twin participants aged 7-15 years were selected from Guangzhou Twin Eye Study..Ocular examinations included vi-sual acuity measurement, ocular motility evaluation, autore-fraction under cycloplegia, and anterior segment, media, and fundus examination...Axial length (AL),..anterior cham ber depth (ACD), and corneal curvature radius were measured us-ing partial coherence laser interferometry. A multivariate linear regression model was used for statistical analysis.Results:.Twin children from Guangzhou city showed a de-creased spherical equivalent with age,.whereas both AL and ACD were increased and corneal curvature radius remained unchanged. When adjusted by age and gender, the data from 77% of twins presenting with spherical equivalent changes in-dicated that these were caused by predictable variables. (R2=0.77, P<0.001). Primary factors affecting children's refraction included axial length (β=-0.97,P<0.001), ACD (β=0.33,P<0.001), and curvature radius (β=2.10,P<0.001). Girls had a higher tendency for myopic status than did boys (β=-0.26,P<0.001)..Age exerted no effect upon the changes in refraction (β=-0.01, P=0.25).Conclusion:.Refraction is correlated with ocular biometrics. Refractive status is largely determined by axial length as the major factor. (Eye Science 2014; 29:129-133)

  18. Development of the conceptual framework for the Eye-Drop Satisfaction Questionnaire (EDSQ© in glaucoma using a qualitative study

    Directory of Open Access Journals (Sweden)

    Trudeau Elyse

    2007-08-01

    Full Text Available Abstract Background Compliance is a major issue in glaucoma care. It is usually poor in glaucomatous patients, and may ultimately result in an acceleration of the disease progression and a risk of blindness. Reasons for this poor compliance are complex and multifactorial, amongst which patient satisfaction can be counted. The objective of this study was to develop a questionnaire to assess patient satisfaction and compliance with eye-drop treatment. Methods A qualitative study was carried out to develop the questionnaire. An interview guide was developed based on a literature review. Structured interviews of fifteen French and English patients with primary open-angle glaucoma or intraocular hypertension were conducted by trained interviewers of the native language of the interviewees. General concepts and subconcepts were identified from the transcripts. The questionnaire was developed using the patient verbatim, and submitted to six patients (French and English for cognitive debriefing. Following patients' comments, items were modified and restructured, and a pilot questionnaire was designed. Results Analysis of data from the interviews with patients and clinicians resulted in the elicitation of concepts related to patient satisfaction and compliance with glaucomatous treatment. These were further refined and used to generate a test questionnaire, which consisted of 46 items grouped into 6 domains: patient characteristics, treatment characteristics, patient-clinician relationship, patient experience with the disease and the treatment, interaction between the patient and the treatment, and patient knowledge of the disease and the treatment. Conclusion The Eye-Drop Satisfaction Questionnaire (EDSQ conceptual framework and items were developed simultaneously in French and in English. This questionnaire could be used to evaluate patient satisfaction and compliance with eye-drop treatment and would facilitate the identification of patients at risk

  19. "I kissed a girl and I liked it": an eye-tracking study of women's sexual fluidity

    OpenAIRE

    Wesson, Charlotte

    2015-01-01

    Heterosexual women’s sexuality differs from men’s as it is seen as more ‘fluid’ (Baumeister, 2000). One explanation of this is that men attend to the gender of stimuli, whereas women attend to the sexuality, with sexual activity in the stimulus a stronger determinant of women’s sexual response (Chivers, et al., 2007). The present study aimed to further investigate whether women’s sexuality is more fluid by looking at the abovementioned claim. Eye-tracking and self-repor...

  20. Sub-lethal Ocular Trauma (SLOT): Establishing a Standardized Blast Threshold to Facilitate Diagnostic, Early Treatment, and Recovery Studies for Blast Injuries to the Eye and Optic Nerve

    Science.gov (United States)

    2015-11-01

    Combat Eye Protection Program (MCEP) provides ballistic or fragment protection, but the ability of current eyewear to protect eyes from the potentially...tissue constitutive models. Another practical approach would be to perform a forensic review of daily accident/battlefield incident reports for...study of paintball impact ocular trauma, Proceedings 24th International Symposium on Ballistics , 1260-1267. Gray, W., Sponsel, W.E., Scribbick, F.W

  1. Marek's disease virus infection in the eye: chronological study of the lesions, virus replication, and vaccine-induced protection.

    Science.gov (United States)

    Pandiri, Arun K R; Cortes, Aneg L; Lee, Lucy F; Gimeno, I M

    2008-12-01

    Marek's disease virus (MDV) infection in the eye was studied chronologically after inoculating 1-day-old chickens with a very virulent MDV strain, Md5. The ocular lesions could be classified as early lesions (6-11 days postinoculation [dpi]) and late lesions (26 and 56 dpi), based upon the location and severity of the lesions. The early lesions involved iris, ciliary body, and choroid layer, and were characterized by endothelial cell hypertrophy, vasculitis, and infiltration of lymphocytes (mainly CD8+), plasma cells, macrophages, and heterophils. Expression of early MDV-antigen pp38 in the cells infiltrating choroid layer was detected as early as 11 dpi. Late lesions consisted of severe lymphohistiocytic uveitis, keratitis, pectenitis, vitreitis, retinitis, and segmental to diffuse retinal necrosis. Cell infiltration included macrophages, granulocytes, plasma cells, and both CD4+ and CD8+ cells of various sizes. Expression of early MDV-antigen pp38 was readily found within the retina, uveal tract, and corneal epithelium. No expression of late-antigen gB or oncoprotein meq was detected in any of the eyes examined. A second experiment was conducted to study the effect of vaccination on the development of ocular lesions. Both HVT and CVI988 were able to protect against the development of early ocular lesions in chickens infected with very virulent plus strain MDV 648A. However, only CVI988 conferred complete protection against the development of late ocular lesions. HVT conferred partial protection, as it reduced the frequency and severity of the late ocular lesions. These results enhance our understanding of the nature and pattern of MDV infection in the eye.

  2. Second-phase validation study of short time exposure test for assessment of eye irritation potency of chemicals.

    Science.gov (United States)

    Kojima, Hajime; Hayashi, Kazuhiko; Sakaguchi, Hitoshi; Omori, Takashi; Otoizumi, Takuya; Sozu, Takashi; Kuwahara, Hirofumi; Hayashi, Takumi; Sakaguchi, Mayumi; Toyoda, Akemi; Goto, Haruka; Watanabe, Shinichi; Ahiko, Kyoko; Nakamura, Tsuneaki; Morimoto, Takashi

    2013-09-01

    A Short Time Exposure (STE) test is a cytotoxicity test that uses SIRC cells (rabbit corneal cell line) to assess eye irritation potency following a 5-min chemical exposure. This second-phase validation study assessed the predictive capacity of the STE test using 40 coded test substances at three laboratories. A Validation Management Team (VMT) then evaluated the predictivity of the STE test for United Nation (UN) Globally Harmonized System (GHS) categories using 63 test substances including the results of the first-phase validation study. The STE test can assess not only the severe or corrosive ocular irritants (corresponding to the UN GHS Category 1) but also non-irritant (corresponding to UN GHS Non Category) from other toxicity classes, especially for limited types of test substances. The predictivity by STE test, however, was insufficient for identification of UN GHS categories (Category 1, Category 2, or Non Category). These results suggest that the STE test can be recommended as an initial step in a top-down approach to identification of severe irritants and test substances that require classification for eye irritation (UN GHS Category 1) as well as an initial step in a bottom-up approach to identification of test substances that do not require classification for eye irritation (UN GHS Non Category) from other toxicity classes, especially for limited types of test substances. On the other hand, the STE test is not considered adequate for the identification of mild or moderate irritants (i.e., UN GHS Categories 2A and 2B) and severe irritants (UN GHS Category 1).

  3. The eye drop chart: a pilot study for improving administration of and compliance with topical treatments in glaucoma patients

    Directory of Open Access Journals (Sweden)

    McVeigh KA

    2015-05-01

    Full Text Available Katherine Anne McVeigh,1 Georgios Vakros21Department of Ophthalmology, Royal United Hospital, Combe Park, Bath, UK; 2Department of Ophthalmology, Queen’s Hospital, Romford, Essex, UKAim: In order to improve patient education, compliance, and administration of eye drops prescribed for patients suffering with glaucoma within a UK ophthalmology department, an eye drop chart (EDC was designed, developed, and piloted with patients attending the glaucoma clinic over 1 month.Methods: A cross-sectional prospective pilot study of 25 patients using an administration aid and a self-reported questionnaire. Chi-square tests were used to compare responses pre- and postintervention.Results: Results demonstrated an impressive improvement in nine of eleven categories assessed regarding drop administration and compliance. Patients stating that they always wash their hands increased significantly from 64% (13 participants to 92% (23 participants (P=0.029, and those who always shake the bottle improved from 40% (10 to 84% (21 (P=0.001. Punctal occlusion techniques improved from 44% (11 to 72% (18 (P=0.015. Finally, patients who always discarded the bottle after 28 days of use rose from 68% to 92%, though the difference was not significant (P=0.09. Only the number of drops being administered to the eye and the length of time left between the application of drops remained relatively unchanged. Sixty-four percent reported finding EDC helpful or useful, 52% had positive responses when asked if they would continue using EDC, and 88% would recommend it to a friend.Conclusion: Although there are limitations to the data as they are subjective, descriptive, and limited to sample size of 25, the results of this pilot study have shown promise. The EDC appears to be a cost-effective way at improving patients’ use of topical ocular medications.Keywords: glaucoma, administration, compliance, aid, drop chart

  4. About the effect of eye blinking on drug release from pHEMA-based hydrogels: an in vitro study.

    Science.gov (United States)

    Galante, R; Paradiso, P; Moutinho, M G; Fernandes, A I; Mata, J L G; Matos, A P A; Colaço, R; Saramago, B; Serro, A P

    2015-01-01

    The development of new ophthalmic drug delivery systems capable of increasing the residence time of drugs in the eye and improve its bioavailability relatively to eyedrops has been object of intense research in recent years. Several studies have shown that drug-loaded therapeutic soft contact lenses (SCLs) constitute a promising approach, with several potential advantages as compared with collyria. The main objective of this work is to study the effect of repetitive load and friction cycles caused by the eye blinking, on the drug release from hydrogels used in SCLs which, as far as we know, was never investigated before. Two poly-2-hydroxyethylmethacrylate-based hydrogels, pHEMA-T and pHEMA-UV, were used as model materials. Levofloxaxin was chosen as model drug. The hydrogels were fully characterized in what concerns structural and physicochemical properties. pHEMA-UV revealed some superficial porosity and a lower short-range order than pHEMA-T. We observe that the load and friction cycles enhanced the drug release from pHEMA-UV hydrogels. The application of a simple mathematical model, which takes into account the drug dilution caused by the tear flow, showed that the enhancement of the drug release caused by blinking on this hydrogel may be relevant in in vivo conditions. Conversely, the more sustained drug release from pHEMA-T is not affected by load and friction cycles. The conclusion is that, depending on the physicochemical and microstructural characteristics of the hydrogels, blinking is a factor that may affect the amount of drug delivered to the eye by SCLs and should thus be considered.

  5. Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt

    Institute of Scientific and Technical Information of China (English)

    Nizar; Saleh; Abdelfattah; Mohamed; Amgad; Ahmed; A; Salama; Marina; E; Israel; Ghada; A; Elhawary; Ahmed; E; Radwan; Mohamed; M; Elgayar; Tamer; M; EL; Nakhal; Islam; T; Elkhateb; Heba; A; Hashem; Doha; K; Embaby; Amira; A; Elabd; Reem; K; Elwy; Magdi; S; Yacoub; Hamdy; Salem; Mohamed; Abdel-Baqy; Ahmad; Kassem

    2014-01-01

    AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination.

  6. Study on algorithm of dynamic uncalibrated eye-in-hand visual servoing system

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Currently, most visual servoing system must be calibrated, while it is impossible to calibrate cameras and robot models precisely in industrial practice, so a novel dynamic uncalibrated eye-in-hand visual servoing system of tracking a moving target is proposed. The method does not require calibration of camera and robot kinematic models. Vision guided algorithm for tracking dynamic image is developed through minimizing nonlinear objective function. For the large residual has not been approximated in dynamic environment and the change of composite image Jacobian with time increment has not been computed in visual servoing system now,large residuals are dynamic approximated and the change of composite image Jacobian at each iterative step is computed.Simulation results demonstrate the validity of these approaches.

  7. Sources of variation in developmental language disorders: evidence from eye-tracking studies of sentence production.

    Science.gov (United States)

    Norbury, Courtenay Frazier

    2014-01-01

    Skilled sentence production involves distinct stages of message conceptualization (deciding what to talk about) and message formulation (deciding how to talk about it). Eye-movement paradigms provide a mechanism for observing how speakers accomplish these aspects of production in real time. These methods have recently been applied to children with autism spectrum disorder (ASD) and specific language impairment (LI) in an effort to reveal qualitative differences between groups in sentence production processes. Findings support a multiple-deficit account in which language production is influenced not only by lexical and syntactic constraints, but also by variation in attention control, inhibition and social competence. Thus, children with ASD are especially vulnerable to atypical patterns of visual inspection and verbal utterance. The potential to influence attentional focus and prime appropriate language structures are considered as a mechanism for facilitating language adaptation and learning.

  8. Capabilities of the bathymetric Hawk Eye LiDAR for coastal habitat mapping: A case study within a Basque estuary

    Science.gov (United States)

    Chust, Guillem; Grande, Maitane; Galparsoro, Ibon; Uriarte, Adolfo; Borja, Ángel

    2010-10-01

    The bathymetric LiDAR system is an airborne laser that detects sea bottom at high vertical and horizontal resolutions in shallow coastal waters. This study assesses the capabilities of the airborne bathymetric LiDAR sensor (Hawk Eye system) for coastal habitat mapping in the Oka estuary (within the Biosphere Reserve of Urdaibai, SE Bay of Biscay, northern Spain), where water conditions are moderately turbid. Three specific objectives were addressed: 1) to assess the data quality of the Hawk Eye LiDAR, both for terrestrial and subtidal zones, in terms of height measurement density, coverage, and vertical accuracy; 2) to compare bathymetric LiDAR with a ship-borne multibeam echosounder (MBES) for different bottom types and depth ranges; and 3) to test the discrimination potential of LiDAR height and reflectance information, together with multi-spectral imagery (three visible and near infrared bands), for the classification of 22 salt marsh and rocky shore habitats, covering supralittoral, intertidal and subtidal zones. The bathymetric LiDAR Hawk Eye data enabled the generation of a digital elevation model (DEM) of the Oka estuary, at 2 m of horizontal spatial resolution in the terrestrial zone (with a vertical accuracy of 0.15 m) and at 4 m within the subtidal, extending a water depth of 21 m. Data gaps occurred in 14.4% of the area surveyed with the LiDAR (13.69 km 2). Comparison of the LiDAR system and the MBES showed no significant mean difference in depth. However, the Root Mean Square error of the former was high (0.84 m), especially concentrated upon rocky (0.55-1.77 m) rather than in sediment bottoms (0.38-0.62 m). The potential of LiDAR topographic variables and reflectance alone for discriminating 15 intertidal and submerged habitats was low (with overall classification accuracy between 52.4 and 65.4%). In particular, reflectance retrieved for this case study has been found to be not particularly useful for classification purposes. The combination of the Li

  9. Eye-movements and ongoing task processing.

    Science.gov (United States)

    Burke, David T; Meleger, Alec; Schneider, Jeffrey C; Snyder, Jim; Dorvlo, Atsu S S; Al-Adawi, Samir

    2003-06-01

    This study tests the relation between eye-movements and thought processing. Subjects were given specific modality tasks (visual, gustatory, kinesthetic) and assessed on whether they responded with distinct eye-movements. Some subjects' eye-movements reflected ongoing thought processing. Instead of a universal pattern, as suggested by the neurolinguistic programming hypothesis, this study yielded subject-specific idiosyncratic eye-movements across all modalities. Included is a discussion of the neurolinguistic programming hypothesis regarding eye-movements and its implications for the eye-movement desensitization and reprocessing theory.

  10. Eye Contricks

    Directory of Open Access Journals (Sweden)

    N Wade

    2011-04-01

    Full Text Available Icons are eye-cons: they provide a distillation of a complex object or idea into a simple pictorial shape. They create the impression of representing that which cannot be presented. Even at the level of the photograph, the links between icon and object are tenuous. The dimension of distance or depth is missing from the icon, and this alone introduces all manner of potential ambiguities. The history of art can be considered as an exploration of the missing link between icon and object. Eye-cons are more honest—they are tricks of vision so that what is seen does not necessarily correspond to what is presented. They are visual allusions rather than visual illusions, although they can display illusory effects. At its broadest, icon can be equated with image. The concept of image has thrived on its vagueness, and so attempts have been made to refine it. An icon corresponds to an optical image: it shares some of the projective characteristics of the object represented. Written words are also icons but they do not resemble the objects they represent—they are stylised or conventional rather than spatialised and projective. Words and images were set in delightful opposition by René Magritte (1898-1967 in a series of pipe paintings, and he also played on the theme of the arbitrariness of the verbal labels assigned to objects. What is surprising is that Magritte did not apply his painterly skills to transforming the word shapes he used. A similar reluctance to transform the typefaces pervades visual poetry. My interests are in the visual rather than the poetic dimension, and I will present a range of my own eye contricks which play with letter and word shapes in a variety of ways.

  11. Individual differences in smoking-related cue reactivity in smokers: an eye-tracking and fMRI study.

    Science.gov (United States)

    Kang, O-Seok; Chang, Dong-Seon; Jahng, Geon-Ho; Kim, Song-Yi; Kim, Hackjin; Kim, Jong-Woo; Chung, Sun-Yong; Yang, Seung-In; Park, Hi-Joon; Lee, Hyejung; Chae, Younbyoung

    2012-08-07

    Measures of cue reactivity provide a means of studying and understanding addictive behavior. We wanted to examine the relationship between different cue reactivity measures, such as attentional bias and subjective craving, and functional brain responses toward smoking-related cues in smokers. We used eye-tracking measurements, a questionnaire for smoking urges-brief and functional magnetic resonance imaging to assess the responses to smoking-related and neutral visual cues from 25 male smokers after 36 h of smoking abstinence. Regression analyses were conducted to determine the correlation between cue-evoked brain responses and the attentional bias to smoking-related cues. The eye gaze dwell time percentage was longer in response to smoking-related cues than neutral cues, indicating significant differences in attentional bias towards smoking-related cues. The attentional bias to smoking-related cues correlated with subjective craving ratings (r=0.660, psmoking-related cues, whereas the orbitofrontal cortex, the insula and the superior temporal gyrus were associated with smoking-related cue-induced craving and smoking urges. These results suggest that attentional mechanisms in combination with motivational and reward-related mechanisms play a role in smoking-related cue reactivity. We confirmed a positive correlation between different smoking-related cue reactivities, such as attentional bias and subjective craving, and functional brain responses in various individuals. Further studies in this field might contribute to a better individualized understanding of addictive behavior.

  12. A study to assess the feasibility of undertaking a randomized controlled trial of adherence with eye drops in glaucoma patients

    Directory of Open Access Journals (Sweden)

    Richardson C

    2013-10-01

    Full Text Available Cliff Richardson,1 Lisa Brunton,1 Nicola Olleveant,1 David B Henson,1 Mark Pilling,1 Jane Mottershead,2 Cecilia H Fenerty,2 Anne Fiona Spencer,2 Heather Waterman1 1School of Nursing, Midwifery and Social Work, University of Manchester, 2Royal Manchester Eye Hospital, Central Manchester Foundation Trust, Manchester, United Kingdom Background: Adherence with therapy could influence the progression of glaucoma and ultimately affect the onset of visual impairment in some individuals. This feasibility study evaluated the measures to be used for a future randomized controlled trial assessing the effects of group-based education on adherence with eye drops. Methods: People diagnosed with glaucoma within the previous 12 months attending a regional ophthalmology clinic in the North West of England were recruited. A two-session education program delivered one week apart had been devised as part of a previous project. A combined adult learning and health needs approach to education was taken. Outcomes measured were knowledge of glaucoma, self-report of adherence, illness perception, beliefs about medicines, patient enablement, and general health (Short Form-12. Adherence was also measured objectively using a Medical Events Monitoring System device. Results: Twenty-six participants consented to undertake the educational program and 19 produced analyzable data. Knowledge of glaucoma, illness perception, beliefs about medicine, and patient enablement all showed statistically significant improvements after education. Mean adherence with eye drops was maintained above 85% before and for 3 months after attendance at the educational program. Self-report exaggerated adherence by at least 10% when compared with the objective Medical Events Monitoring System data, and in fact the kappa agreement was zero. Conclusion: All questionnaires other than the Short Form-12 were considered to be valuable measures and use of a Medical Events Monitoring System device was

  13. Freqüência de hemolisinas anti-A e anti-B em doadores de sangue do Hemocentro de Botucatu Anti-A and anti-B hemolysin frequencies in blood donors from the Hemotherapy Center of Unesp, Botucatu

    Directory of Open Access Journals (Sweden)

    Sheley Gambero

    2004-03-01

    Full Text Available O Sistema ABO foi descoberto em 1900 e permanece até hoje como sendo o sistema mais importante dentro da prática transfusional. A transfusão ABO incorreta pode resultar na morte do paciente, com uma reação hemolítica intravascular, seguida de alterações imunológicas e bioquímicas. Os anticorpos ABO estão presentes nos soros dos indivíduos, dirigidos contra os antígenos A e/ou B ausentes nas hemácias. Embora as transfusões com pequenas quantias de plasmas incompatíveis sejam geralmente consideradas uma prática segura, alguns casos de reações hemolíticas por plasma incompatível são encontrados na literatura. Tendo em vista a pequena quantidade de estudos sobre as hemolisinas anti-A e anti-B e a importância desses anticorpos na prática transfusional, objetivamos neste trabalho verificar a freqüência dessas hemolisinas em doadores de sangue do Hemocentro da Unesp de Botucatu. Foram analisadas 600 amostras de soros de doadores do grupo "O" para presença ou ausência das hemolisinas anti-A e anti-B. Desses doadores, 77 (12,8% foram classificados como perigosos por apresentarem em seu soro altos títulos de hemolisinas e 523 (87,2% como não perigosos por apresentarem baixos títulos. No grupo dos doadores perigosos, 45 (58,4% foram reativos para hemolisina anti-A, 11 (14,2% reativos para hemolisina anti-B e 21 (27,2% reativos para ambas. O título de aglutininas superior a 1/100 já considera o doador "O" como perigoso. Assim, o teste realizado em nossa rotina é suficiente para detecção de altos títulos fazendo com que os pacientes dos outros grupos sangüíneos não corram o risco de reação transfusional se necessitarem de transfusão sangüínea não-isogrupo.The ABO system was discovered in 1990 and remains until today the most important system in transfusional practice. The wrong ABO transfusion can result in death of the patient after a hemolytic reaction followed by immunological and biochemical changes. ABO

  14. The Association between Dry Eye Disease and Physical Activity as well as Sedentary Behavior: Results from the Osaka Study

    Directory of Open Access Journals (Sweden)

    Motoko Kawashima

    2014-01-01

    Full Text Available Purpose. To assess the association of dry eye disease (DED with physical activity and sedentary behavior. Methods. The cross-sectional survey conducted included Japanese office workers who use visual display terminals (n=672. DED was assessed according to the Japanese Dry Eye Diagnostic Criteria, and participants were categorized into “definite DED,” “probable DED,” or “non-DED” groups based on the results of DED examinations. Physical activity and sedentary behavior of participants were assessed using the International Physical Activity Questionnaire (IPAQ, and physical activity level was calculated in metabolic equivalent units per week (MET, min/week. Participants were classified as having a high, moderate, or low level of physical activity. Results. Participants with abnormal tear break-up time (BUT (≤5 s were involved in sedentary behavior for significantly longer duration than those with normal BUT (P=0.035. Non-DED participants (14.5% tended to have higher levels of physical activity than definite DED participants (2.5%. Participants with definite DED had significantly lower MET scores than those with non-DED (P=0.025. Conclusions. Our findings suggest that a lower level of physical activity and sedentary behavior are associated with DED; however, longitudinal/intervention studies with large groups of participants are needed to validate these findings.

  15. The processing of raising and nominal control: An eye-tracking study

    Directory of Open Access Journals (Sweden)

    Patrick eSturt

    2015-03-01

    Full Text Available According to some views of sentence processing, the memory retrieval processes involved in dependency formation may differ as a function of the type of dependency involved. For example, using closely matched materials in a single experiment Dillon et al (2013 found evidence for retrieval interference in subject-verb agreement, but not in reflexive-antecedent agreement. We report four eye-tracking experiments that examine examine reflexive-antecedent dependencies, combined with raising (e.g. ``John seemed to Tom to be kind to himself...'', or nominal control (e.g. ``John’s agreement with Tom to be kind to himself...''. We hypothesized that dependencies involving raising would (a be processed more quickly, and (b be less subject to retrieval interference, relative to those involving nominal control. This is due to the fact that the interpretation of raising is structurally constrained, while the interpretation of nominal control depends crucially on lexical properties of the control nominal. The results showed evidence of interference when the reflexive-antecedent dependency was mediated by raising or nominal control, but very little evidence that could be interpreted in terms of interference for direct reflexive-antecedent dependencies that did not involve raising or control. However, there was no evidence either for greater interference, or for quicker dependency formation, for raising than for nominal control.

  16. Effects of Four Formulations of Prostaglandin Analogs on Eye Surface Cells. A Comparative Study.

    Directory of Open Access Journals (Sweden)

    Fernando Pérez-Roca

    Full Text Available We evaluated the cytotoxic effects of four prostaglandin analogs (PGAs used to treat glaucoma. First we established primary cultures of conjunctival stromal cells from healthy donors. Then cell cultures were incubated with different concentrations (0, 0.1, 1, 5, 25, 50 and 100% of commercial formulations of bimatoprost, tafluprost, travoprost and latanoprost for increasing periods (5 and 30 min, 1 h, 6 h and 24 h and cell survival was assessed with three different methods: WST-1, MTT and calcein/AM-ethidium homodimer-1 assays. Our results showed that all PGAs were associated with a certain level of cell damage, which correlated significantly with the concentration of PGA used, and to a lesser extent with culture time. Tafluprost tended to be less toxic than bimatoprost, travoprost and latanoprost after all culture periods. The results for WST-1, MTT and calcein/AM-ethidium homodimer-1 correlated closely. When the average lethal dose 50 was calculated, we found that the most cytotoxic drug was latanoprost, whereas tafluprost was the most sparing of the ocular surface in vitro. These results indicate the need to design novel PGAs with high effectiveness but free from the cytotoxic effects that we found, or at least to obtain drugs that are functional at low dosages. The fact that the commercial formulation of tafluprost used in this work was preservative-free may support the current tendency to eliminate preservatives from eye drops for clinical use.

  17. Eye movement desensitization and reprocessing in addiction continuing care: a phenomenological study of women in recovery.

    Science.gov (United States)

    Marich, Jamie

    2010-09-01

    Traditional models of addiction treatment and relapse prevention fail to consider the role that unresolved trauma plays in an addicted woman's recovery experience. Implementing Eye Movement Desensitization and Reprocessing (EMDR) into the treatment process offers a potential solution to this problem. Ten women (alumnae of an extended-care treatment facility) participated in a semistandardized interview to share their experiences with active addiction, treatment, EMDR therapy, and recovery. With the use of A. P. Giorgi's descriptive phenomenological psychological method for analysis, four major thematic areas emerged from the interview data: the existence of safety as an essential crucible of the EMDR experience, the importance of accessing the emotional core as vital to the recovery experience, the role of perspective shift in lifestyle change, and the use of a combination of factors for successful treatment. All 10 women, to some degree, credited EMDR treatment as a crucial component of their addiction continuing-care processes, especially in helping with emotional core access and perspective shift. Implications emerge from the data on how to best implement EMDR into a comprehensive addiction treatment program.

  18. How do neural responses to eyes contribute to face-sensitive ERP components in young infants? A rapid repetition study.

    Science.gov (United States)

    Hoehl, Stefanie

    2015-04-01

    Several face-sensitive components of the event-related potential (ERP) have been identified in infants, such as the posterior N290 and P400 components. The contribution of eye-sensitive neurons to these components is still unclear, however. A rapid repetition ERP paradigm was used to test 4-month-olds' responses to faces with and without eyes (preceded by houses, i.e., unprimed) and faces with eyes that were preceded by faces with or without eyes (i.e., primed). N290 latency was reduced and P400 amplitude was increased for unprimed faces without eyes compared to intact faces. In addition, N290 latency was reduced for faces preceded by intact faces compared to faces preceded by faces without eyes. Thus, processing speed at the level of the N290 and amplitude of the P400 are affected by the absence of eyes in a face supporting the notion that eye-sensitive neurons contribute to these components in infancy. Findings are discussed in relation to the early development of face processing and infant and adult ERP responses to faces and eyes.

  19. Erros de refração como causas de baixa visual em crianças da rede de escolas públicas da regional de Botucatu - SP Refractive errors as causes of visual impairment in children from public schools of the Botucatu region - SP

    Directory of Open Access Journals (Sweden)

    Claudia Akemi Shiratori de Oliveira

    2009-04-01

    Full Text Available OBJETIVO: Estudar a ocorrência dos erros refracionais em escolares de nosso meio. MÉTODOS: Estudo transversal avaliando crianças da pré-escola e do ensino básico, quanto ao sexo, tipo de erro refracional, acuidade visual e tratamento realizado. RESULTADOS: Quatro mil seiscentos e vinte e três crianças foram submetidas a exame de acuidade visual, das quais 8,1% apresentaram necessidade de exame oftalmológico completo. Houve 63,2% de portadores de astigmatismo hipermetrópico, 15,7% de astigmatismo miópico, 12,5% de astigmatismo misto, 4,9% de hipermetropia e 3,7% de miopia. Foi indicada a prescrição de lentes corretoras para 48,7% da amostra estudada. A frequência de erros refracionais na população foi de 3,9%. CONCLUSÃO: O astigmatismo hipermetrópico foi o erro de refracional mais frequente, havendo necessidade de tratamento em cerca de 50% das crianças triadas com frequência de 3,9% de erro refracional passível de correção na população de estudo.PURPOSE: To evaluate the refractive errors as cause of visual impairment in school children from the Botucatu region. METHODS: A sectional study was conducted evaluating preschool and elementary school students, according to gender, refractive error, visual acuity and treatment. RESULTS: Four thousand six hundred and twenty-three (4,623 children were submitted to visual acuity evaluation and 8.1% of them were submitted to complete ocular examination. There were 63.2% hyperopic astigmatism, 15.7% myopic astigmatism, 12.5% astigmatism, 4.9% hyperopia and 3.7% myopia. Corrective lenses were prescribed for 48.7% of the evaluated children. CONCLUSION: The most frequent refractive error was hyperopic astigmatism and 50% of the children received treatment. The frequency of refractive errors was 3.9% of the studied population.

  20. About the Eye

    Medline Plus

    Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks Links to More Information Optical Illusions Printables About the Eye Your eyes ...

  1. Recognition of Facial Expressions in Individuals with Elevated Levels of Depressive Symptoms: An Eye-Movement Study

    Directory of Open Access Journals (Sweden)

    Lingdan Wu

    2012-01-01

    Full Text Available Previous studies consistently reported abnormal recognition of facial expressions in depression. However, it is still not clear whether this abnormality is due to an enhanced or impaired ability to recognize facial expressions, and what underlying cognitive systems are involved. The present study aimed to examine how individuals with elevated levels of depressive symptoms differ from controls on facial expression recognition and to assess attention and information processing using eye tracking. Forty participants (18 with elevated depressive symptoms were instructed to label facial expressions depicting one of seven emotions. Results showed that the high-depression group, in comparison with the low-depression group, recognized facial expressions faster and with comparable accuracy. Furthermore, the high-depression group demonstrated greater leftwards attention bias which has been argued to be an indicator of hyperactivation of right hemisphere during facial expression recognition.

  2. An excerpt from an eye-tracking comparative study between Poland and Japan with the use of Force Concept Inventory

    Science.gov (United States)

    Rosiek, Roman; Sajka, Mirosława; Ohno, Eizo; Shimojo, Atsushi; Iwata, Michiru; Wcisło, Dariusz

    2017-01-01

    The paper presents the initial results of a comparative Polish-Japanese study. The research was conducted at the Department of Mathematics, Physics and Technical Science at the Pedagogical University of Cracow and at the University of Hokkaido. The participants of the study were university students of humanistic courses. The research concerns the comparison of the respondents' knowledge and understanding of the concept of force in mechanics and their ways of solving problems in the field of a basic mechanics course. A special theoretical tool was used. It was the standardized, international test diagnosing the understanding of the concept of force - the so-called "Force Concept Inventory" (FCI), in its official Polish and Japanese translations. The eye-tracking method was combined with structured interviews and discussions with all the respondents.

  3. The IMPACT study: a prospective evaluation of the effects of cyclosporine ophthalmic emulsion 0.05% on ocular surface staining and visual performance in patients with dry eye

    Directory of Open Access Journals (Sweden)

    Stonecipher KG

    2016-05-01

    Full Text Available Karl G Stonecipher,1,2 Gail L Torkildsen,3 George W Ousler III,4 Scot Morris,5 Linda Villanueva,6 David A Hollander6 1Department of Ophthalmology, University of North Carolina, Chapel Hill, 2TLC Laser Eye Centers, Greensboro, NC, 3Andover Eye Associates, 4Ora, Inc., Andover, MA, 5Eye Consultants of Colorado, Conifer, CO, 6Allergan plc, Irvine, CA, USA Objective: The aim of this study was to evaluate the effects of cyclosporine ophthalmic emulsion 0.05% on ocular surface staining and visual performance in patients with dry eye.Methods: This was a single-center, 6-month, open-label, Phase IV study. Patients with bilateral dry eye disease and a symptom score of ≥2 on the Ocular Discomfort and 4-Symptom Questionnaire, an Ocular Surface Disease Index score of >12, at least one eye with Schirmer’s score <10 mm/5 minutes, and central corneal staining graded as ≥2 on the Ora Calibra™ Corneal and Conjunctival Staining Scale were enrolled. Cyclosporine ophthalmic emulsion 0.05% (Restasis® was instilled twice daily in each eye. The primary efficacy endpoints were ocular surface staining and visual function at 6 months. Secondary outcome measures included Schirmer’s test, tear film breakup time, symptoms, and adverse events.Results: A total of 40 patients with the mean age of 59.4 years (range, 40–78 years were enrolled; 35 (87.5% were female and 37 (92.5% completed the study. At 6 months, inferior corneal, central corneal, total corneal, and total ocular surface fluorescein staining were significantly improved from baseline in both eyes (P<0.001. Patient responses on the Ocular Surface Disease Index showed significant improvement in blurred vision and visual function related to reading, driving at night, working with a computer or bank machine, and watching television (P≤0.041. At 6 months, 35.1% of patients achieved ≥5 mm improvement and 18.9% achieved ≥10 mm improvement in the average eye Schirmer score. Mean tear film breakup

  4. An experimental study on the effects of curcumin on posterior capsule opacification in young rabbit eyes

    Institute of Scientific and Technical Information of China (English)

    WANG Wen-ying; ZHANG Zhu-jun; WANG Jun; WANG Hai-wei

    2011-01-01

    Background Posterior capsule opacification (PCO) compromises vision development in infants after cataract surgery and lead to amblyopia.To observe the effects of curcumin on PCO in infant rabbits,curcumin was injected under the capaule and into the anterior chamber during phacoemulsification.Methods Seventy-five 1-month-old healthy New Zealand white rabbits were randomized into 3 groups,one eye of each rabbit was randomly selected to be operated.The operation involved continuous circular capsulorhexis,followed by hydrodissection with 0.6 ml each of balanced salt solution (BSS,group A),hydroxypropyl-β-dodextrin (HP-β-CD,90μg/ml,group B) or CUR-HP-β-CD (123 μg/ml,group C),respectively.After phacoemulsification,0.4 ml of each drug solution was injected into the anterior chamber via an incision.The extent of corneal edema and the inflammatory response within the anterior chamber were considered as measures PCO and observed postoperatively.All eyes were examined 1 and 2 months postoperative by slit lamp microscopy and photography after pupil dilation.On the third day postoperative,6 rabbits from each group were executed.Paraffin-embedded sections were stained with hematoxylin-eosin (HE) or terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay (TUNEL,indicative of apoptosis).Stained sections were observed under light microscopy.Proliferation of lens epithelial cells (LECs) was observed microscopically on day 3,day 7,month 1 and month 2 after the operation with HE staining.Results The remission of cornea edema occurred earlier in group C than in groups A and B (P <0.05); there were no significant differences between groups A and B.The remission of anterior chamber exudation in group C was earlier than those in groups A and B (P <0.05).No significant difference in the times when PCO occurred,was observed among groups.Compared to groups A and B,the extent of PCO was less severe (P <0.05).Three days after the operation,LECs aggregated

  5. A New Safety Concern for Glaucoma Treatment Demonstrated by Mass Spectrometry Imaging of Benzalkonium Chloride Distribution in the Eye, an Experimental Study in Rabbits

    Science.gov (United States)

    Brignole-Baudouin, Françoise; Desbenoit, Nicolas; Hamm, Gregory; Liang, Hong; Both, Jean-Pierre; Brunelle, Alain; Fournier, Isabelle; Guerineau, Vincent; Legouffe, Raphael; Stauber, Jonathan; Touboul, David; Wisztorski, Maxence; Salzet, Michel; Laprevote, Olivier; Baudouin, Christophe

    2012-01-01

    We investigated in a rabbit model, the eye distribution of topically instilled benzalkonium_(BAK) chloride a commonly used preservative in eye drops using mass spectrometry imaging. Three groups of three New Zealand rabbits each were used: a control one without instillation, one receiving 0.01%BAK twice a day for 5 months and one with 0.2%BAK one drop a day for 1 month. After sacrifice, eyes were embedded and frozen in tragacanth gum. Serial cryosections were alternately deposited on glass slides for histological (hematoxylin-eosin staining) and immunohistological controls (CD45, RLA-DR and vimentin for inflammatory cell infiltration as well as vimentin for Müller glial cell activation) and ITO or stainless steel plates for MSI experiments using Matrix-assisted laser desorption ionization time-of-flight. The MSI results were confirmed by a round-robin study on several adjacent sections conducted in two different laboratories using different sample preparation methods, mass spectrometers and data analysis softwares. BAK was shown to penetrate healthy eyes even after a short duration and was not only detected on the ocular surface structures, but also in deeper tissues, especially in sensitive areas involved in glaucoma pathophysiology, such as the trabecular meshwork and the optic nerve areas, as confirmed by images with histological stainings. CD45-, RLA-DR- and vimentin-positive cells increased in treated eyes. Vimentin was found only in the inner layer of retina in normal eyes and increased in all retinal layers in treated eyes, confirming an activation response to a cell stress. This ocular toxicological study confirms the presence of BAK preservative in ocular surface structures as well as in deeper structures involved in glaucoma disease. The inflammatory cell infiltration and Müller glial cell activation confirmed the deleterious effect of BAK. Although these results were obtained in animals, they highlight the importance of the safety-first principle for

  6. A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits.

    Directory of Open Access Journals (Sweden)

    Françoise Brignole-Baudouin

    Full Text Available We investigated in a rabbit model, the eye distribution of topically instilled benzalkonium_(BAK chloride a commonly used preservative in eye drops using mass spectrometry imaging. Three groups of three New Zealand rabbits each were used: a control one without instillation, one receiving 0.01%BAK twice a day for 5 months and one with 0.2%BAK one drop a day for 1 month. After sacrifice, eyes were embedded and frozen in tragacanth gum. Serial cryosections were alternately deposited on glass slides for histological (hematoxylin-eosin staining and immunohistological controls (CD45, RLA-DR and vimentin for inflammatory cell infiltration as well as vimentin for Müller glial cell activation and ITO or stainless steel plates for MSI experiments using Matrix-assisted laser desorption ionization time-of-flight. The MSI results were confirmed by a round-robin study on several adjacent sections conducted in two different laboratories using different sample preparation methods, mass spectrometers and data analysis softwares. BAK was shown to penetrate healthy eyes even after a short duration and was not only detected on the ocular surface structures, but also in deeper tissues, especially in sensitive areas involved in glaucoma pathophysiology, such as the trabecular meshwork and the optic nerve areas, as confirmed by images with histological stainings. CD45-, RLA-DR- and vimentin-positive cells increased in treated eyes. Vimentin was found only in the inner layer of retina in normal eyes and increased in all retinal layers in treated eyes, confirming an activation response to a cell stress. This ocular toxicological study confirms the presence of BAK preservative in ocular surface structures as well as in deeper structures involved in glaucoma disease. The inflammatory cell infiltration and Müller glial cell activation confirmed the deleterious effect of BAK. Although these results were obtained in animals, they highlight the importance of the safety

  7. Individual Differences in Executive Control Relate to Metaphor Processing: An Eye Movement Study of Sentence Reading

    Directory of Open Access Journals (Sweden)

    Georgie eColumbus

    2015-01-01

    Full Text Available Metaphors are common elements of language that allow us to creatively stretch the limits of word meaning. However, metaphors vary in their degree of novelty, which determines whether people must create new meanings on-line or retrieve previously known metaphorical meanings from memory. Such variations affect the degree to which general cognitive capacities such as executive control are required for successful comprehension.We investigated whether individual differences in executive control relate to metaphor processing using eye movement measures of reading. Thirty-nine participants read sentences including metaphors or idioms, another form of figurative language that is more likely to rely on meaning retrieval. They also completed the AX-CPT, a domain-general executive control task. In Experiment 1, we examined sentences containing metaphorical or literal uses of verbs, presented with or without prior context. In Experiment 2, we examined sentences containing idioms or literal phrases for the same participants to determine whether the link to executive control was qualitatively similar or different to Experiment 1.When metaphors were low familiar, all people read verbs used as metaphors more slowly than verbs used literally (this difference was smaller for high familiar metaphors. Executive control capacity modulated this pattern in that high executive control readers spent more time reading verbs when a prior context forced a particular interpretation (metaphorical or literal, and they had faster total metaphor reading times when there was a prior context. Interestingly, executive control did not relate to idiom processing for the same readers. Here, all readers had faster total reading times for high familiar idioms than literal phrases. Thus, executive control relates to metaphor but not idiom processing for these readers, and for the particular metaphor and idiom reading manipulations presented.

  8. Topics on distance correlation, feature screening and lifetime expectancy with application to Beaver Dam eye study data

    Science.gov (United States)

    Kong, Jing

    This thesis includes 4 pieces of work. In Chapter 1, we present the work with a method for examining mortality as it is seen to run in families, and lifestyle factors that are also seen to run in families, in a subpopulation of the Beaver Dam Eye Study that has died by 2011. We find significant distance correlations between death ages, lifestyle factors, and family relationships. Considering only sib pairs compared to unrelated persons, distance correlation between siblings and mortality is, not surprisingly, stronger than that between more distantly related family members and mortality. Chapter 2 introduces a feature screening procedure with the use of distance correlation and covariance. We demonstrate a property for distance covariance, which is incorporated in a novel feature screening procedure based on distance correlation as a stopping criterion. The approach is further implemented to two real examples, namely the famous small round blue cell tumors data and the Cancer Genome Atlas ovarian cancer data Chapter 3 pays attention to the right censored human longevity data and the estimation of lifetime expectancy. We propose a general framework of backward multiple imputation for estimating the conditional lifetime expectancy function and the variance of the estimator in the right censoring setting and prove the properties of the estimator. In addition, we apply the method to the Beaver Dam eye study data to study human longevity, where the expected human lifetime are modeled with smoothing spline ANOVA based on the covariates including baseline age, gender, lifestyle factors and disease variables. Chapter 4 compares two imputation methods for right censored data, namely the famous Buckley-James estimator and the backward imputation method proposed in Chapter 3 and shows that backward imputation method is less biased and more robust with heterogeneity.

  9. EyeGENE

    Data.gov (United States)

    U.S. Department of Health & Human Services — The eyeGENE® Biorepository and corresponding Database contain family history and clinical eye exam data from subjects enrolled in eyeGENE® Program coupled to...

  10. Pink Eye (Conjunctivitis)

    Science.gov (United States)

    ... you have allergic conjunctivitis. Preventing the spread of pink eye Practice good hygiene to control the spread ... can return to school or child care. Preventing pink eye in newborns Newborns' eyes are susceptible to ...

  11. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Member Services Advocacy Foundation About Subspecialties & More Eye Health Home Annual Meeting Clinical Education Practice Management Member ... Center Redmond Ethics Center Global Ophthalmology Guide Eye Health Find an Ophthalmologist Academy Store Eye Health A- ...

  12. Eye Injuries in Sports

    Science.gov (United States)

    ... in Sports Which sports cause the most eye injuries?Sports cause more than 40,000 eye injuries each ... and racquet sports.When it comes to eye injuries, sports can be classified as low risk, high risk ...

  13. Rapid eye movement-sleep is reduced in patients with acute uncomplicated diverticulitis—an observational study

    DEFF Research Database (Denmark)

    Huang, Chenxi; Alamili, Mahdi; Nielsen, Claus Henrik;

    2015-01-01

    Introduction. Sleep disturbances are commonly found in patients in the postoperative period. Sleep disturbances may give rise to several complications including cardiopulmonary instability, transient cognitive dysfunction and prolonged convalescence. Many factors including host inflammatory respo...... eye movement sleep and fatigue. Conclusion. Total sleep time and rapid eye movement sleep were reduced during nights with active diverticulitis and correlated with markers of inflammation....

  14. The prevalence and causes of bilateral and unilateral blindness in an elderly urban Danish population. The Copenhagen City Eye Study

    DEFF Research Database (Denmark)

    Buch, Helena; Vinding, T; La Cour, M

    2001-01-01

    PURPOSE: To study the prevalence and causes of bilateral and unilateral blindness in an elderly urban Danish population. METHODS: Data originated from a Danish epidemiologic cross-sectional random sample population eye survey conducted during the years 1986-1988. The population consisted of 1......,000 inhabitants aged 60 to 80 years in Copenhagen. The participants underwent an extensive ophthalmologic examination. A participation rate of 96.9% was achieved. Any blindness was defined as best-corrected visual acuity (VA) worse than 0.05 (the WHO criteria) and VA of 0.1 or worse (the National criteria (NC......) of blindness). RESULTS: The prevalence rates of bilateral and unilateral blindness were, respectively, 0.53% and 3.38% according to WHO, but 1.06% and 4.44% using NC. Bilateral blindness rose significantly with age (p=0.02). According to NC, age-related macular degeneration (AMD) was the leading cause...

  15. Vision-Related Quality of Life and Appearance Concerns Are Associated with Anxiety and Depression after Eye Enucleation: A Cross-Sectional Study.

    Directory of Open Access Journals (Sweden)

    Juan Ye

    Full Text Available To investigate the association of demographic, clinical and psychosocial variables with levels of anxiety and depression in participants wearing an ocular prosthesis after eye enucleation.This cross-sectional study included 195 participants with an enucleated eye who were attending an ophthalmic clinic for prosthetic rehabilitation between July and November 2014. Demographic and clinical data, and self-reported feelings of shame, sadness and anger were collected. Participants also completed the National Eye Institute Visual Function Questionnaire, the Facial Appearance subscale of the Negative Physical Self Scale, and the Hospital Anxiety and Depression Scale. Regression models were used to identify the factors associated with anxiety and depression.The proportion of participants with clinical anxiety was 11.8% and clinical depression 13.8%. More anxiety and depression were associated with poorer vision-related quality of life and greater levels of appearance concerns. Younger age was related to greater levels of anxiety. Less educated participants and those feeling more angry about losing an eye are more prone to experience depression. Clinical variables were unrelated to anxiety or depression.Anxiety and depression are more prevalent in eye-enucleated patients than the general population, which brings up the issues of psychiatric support in these patients. Psychosocial rather than clinical characteristics were associated with anxiety and depression. Longitudinal studies need to be conducted to further elucidate the direction of causality before interventions to improve mood states are developed.

  16. Attention and Recall of Point-of-sale Tobacco Marketing: A Mobile Eye-Tracking Pilot Study

    Directory of Open Access Journals (Sweden)

    Maansi Bansal-Travers

    2016-01-01

    Full Text Available  Introduction: As tobacco advertising restrictions have increased, the retail ‘power wall’ behind the counter is increasingly invaluable for marketing tobacco products. Objective: The primary objectives of this pilot study were 3-fold: (1 evaluate the attention paid/fixations on the area behind the cash register where tobacco advertising is concentrated and tobacco products are displayed in a real-world setting, (2 evaluate the duration (dwell-time of these fixations, and (3 evaluate the recall of advertising displayed on the tobacco power wall. Methods: Data from 13 Smokers (S and 12 Susceptible or non-daily Smokers (SS aged 180–30 from a mobile eye-tracking study. Mobile-eye tracking technology records the orientation (fixation and duration (dwell-time of visual attention. Participants were randomized to one of three purchase tasks at a convenience store: Candy bar Only (CO; N = 10, Candy bar + Specified cigarette Brand (CSB; N = 6, and Candy bar + cigarette Brand of their Choice (CBC; N = 9. A post-session survey evaluated recall of tobacco marketing. Key outcomes were fixations and dwell-time on the cigarette displays at the point-of-sale. Results: Participants spent a median time of 44 seconds during the standardized time evaluated and nearly three-quarters (72% fixated on the power wall during their purchase, regardless of smoking status (S: 77%, SS: 67% or purchase task (CO: 44%, CSB: 71%, CBC: 100%. In the post session survey, nearly all participants (96% indicated they noticed a cigarette brand and 64% were able to describe a specific part of the tobacco wall or recall a promotional offer. Conclusions: Consumers are exposed to point-of-sale tobacco marketing, regardless of smoking status. FDA should consider regulations that limit exposure to point-of-sale tobacco marketing among consumers.

  17. A clinical comparison between DisCoVisc and 2% hydroxypropylmethylcellulose in phacoemulsification: a fellow eye study

    Directory of Open Access Journals (Sweden)

    Rodrigo F. Espíndola

    Full Text Available OBJECTIVE: This study sought to compare the effects and outcomes of two ophthalmic viscosurgical devices, 1.6% hyaluronic acid/4.0% chondroitin sulfate and 2.0% hydroxypropylmethylcellulose, during phacoemulsification. METHODS: This prospective, randomized clinical trial comprised 78 eyes (39 patients that received phacoemulsification performed by the same surgeon using a standardized technique. Patients were randomly assigned to receive either 1.6% hyaluronic acid/4.0% chondroitin sulfate or 2.0% hydroxypropylmethylcellulose on the first eye. The other eye was treated later and received the other viscoelastic agent. Preoperative and postoperative examinations (5, 24 and 48 hours; 7 and 14 days; 3 and 6 months included measurements of the total volume of the ophthalmic viscosurgical device, ultrasound and washout times to completely remove the ophthalmic viscosurgical device, intraocular pressure, central corneal thickness and best-corrected visual acuity. The corneal endothelial cell count was measured at baseline and at six months postoperatively. ClinicalTrials.gov: NCT01387620. RESULTS: There were no statistically significant differences between groups in terms of cataract density or ultrasound time. However, it took longer to remove 2.0% hydroxypropylmethylcellulose than 1.6% hyaluronic acid/ 4.0% chondroitin sulfate, and the amount of viscoelastic material used was greater in the 2.0% hydroxypropylmethylcellulose group. In addition, the best-corrected visual acuity was significantly better in the hyaluronic acid/ chondroitin sulfate group, but this preferable outcome was only observed at 24 hours after the operation. There were no statistically significant differences between the two ophthalmic viscosurgical devices regarding the central corneal thickness or intraocular pressure measurements at any point in time. The corneal endothelial cell count was significantly higher in the hyaluronic acid/chondroitin sulfate group. CONCLUSION: The

  18. Eye tracking the user experience a practical guide to research

    CERN Document Server

    Bojko, Aga

    2013-01-01

    Eye tracking is a widely used research method, but there are many questions and misconceptions about how to effectively apply it. Eye Tracking the User Experience the first how-to book about eye tracking for UX practitioners offers step-by-step advice on how to plan, prepare, and conduct eye tracking studies; how to analyze and interpret eye movement data; and how to successfully communicate eye tracking findings.

  19. DETERMINAÇÃO DO CONSUMO DE ÁGUA E DO COEFICIENTE DE CULTURA DA ABÓBORA NA REGIÃO DE BOTUCATU, SP

    Directory of Open Access Journals (Sweden)

    Elcio Silvério Klosowski

    1999-12-01

    Full Text Available RESUMO O consumo de água pela cultura de abóbora italiana ( Cucurbita pepo L. cultivar Caserta, foi avaliado através de um conjunto de lisímetros de nível de lençol freático na região de Botucatu, SP (latitude 22º51'S, longitude 48º27'W e altitude 786 m. A cultura apresentou maior consumo hídrico no tempo entre a floração e o desenvolvimento dos frutos. O consumo total de água para um ciclo de 70 dias foi de 231,52 mm. Os coeficientes de cultura (kc obtidos variaram entre 0,68 e 1,96.

  20. Study on the most early glass eye-beads in China unearthed from Xu Jialing Tomb in Xichuan of Henan Province,China

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The eye-beads dating to the early Warring States Period unearthed from Xu Jialing Tomb in Xichuan County of Henan Province, China are studied. The structure and the chemical composition of the sam- ples are analysed by the undestructive methods of X-ray diffraction (XRD) and the Proton Induced X-ray Emission (PIXE) technique. The results show that these eye-beads are of glass state. Its chemical composition indicates that they belong to the glass of soda lime silicate system (Na2O-CaO-SiO2). By comparing the decorative design and the chemical composition of the samples with those from ancient Babylon and ancient Egypt, we think that these ancient eye-beads in Xichuan were most possibly im- ported from the West.

  1. Study on the most early glass eye-beads in China unearthed from Xu Jialing Tomb in Xichuan of Henan Province, China

    Institute of Scientific and Technical Information of China (English)

    GAN FuXi; CHENG HuanSheng; HU YongQing; MA Bo; GU DongHong

    2009-01-01

    The eye-beads dating to the early Warring States Period unearthed from Xu Jialing Tomb in Xichuan County of Henan Province, China are studied. The structure and the chemical composition of the samples are analysed by the undestructive methods of X-ray diffraction (XRD) and the Proton Induced X-ray Emission (PIXE) technique. The results show that these eye-beads are of glass state. Its chemical composition indicates that they belong to the glass of soda lime silicate system (Na2O-CaO-SiO2). By comparing the decorative design and the chemical composition of the samples with those from ancient Babylon and ancient Egypt, we think that these ancient eye-beads in Xichuan were most possibly imported from the West.

  2. Eye movement monitoring of memory.

    Science.gov (United States)

    Ryan, Jennifer D; Riggs, Lily; McQuiggan, Douglas A; McQuiggan, Doug

    2010-08-15

    experience. The influence of memory is revealed in the extent to which scanning patterns to new images differ from scanning patterns to images that have been previously studied. Memory can also be interrogated for its specificity; for instance, eye movement patterns that differ between an identical and an altered version of a previously studied image reveal the storage of the altered detail in memory. These indices of memory can be compared across participant populations, thereby providing a powerful tool by which to examine the organization of memory in healthy individuals, and the specific changes that occur to memory with neurological insult or decline.

  3. Spectral power and functional connectivity changes during mindfulness meditation with eyes open: A magnetoencephalography (MEG) study in long-term meditators.

    Science.gov (United States)

    Wong, W P; Camfield, D A; Woods, W; Sarris, J; Pipingas, A

    2015-10-01

    Whilst a number of previous studies have been conducted in order to investigate functional brain changes associated with eyes-closed meditation techniques, there is a relative scarcity in the literature with regards to changes occurring during eyes-open meditation. The current project used magnetoencephalography (MEG) to investigate differences in spectral power and functional connectivity between 11 long-term mindfulness meditators (LTMMs) with >5 years of experience and 12 meditation-naïve control participants both during baseline eyes-open rest and eyes-open open-monitoring (OM) mindfulness meditation. During resting with eyes-open, prior to meditating, greater mean alpha power was observed for LTMMs in comparison to controls. However, during the course of OM meditation, a significantly greater increase in theta power was observed over a broad fronto-centro-parietal region for control participants in comparison to LTMMs. In contrast, whole-head mean connectivity was found to be significantly greater for long-term meditators in comparison to controls in the theta band both during rest as well as during meditation. Additionally, mean connectivity was significantly lower for long-term meditators in the low gamma band during rest and significantly lower in both low and high gamma bands during meditation; and the variance of low-gamma connectivity scores for long-term meditators was significantly decreased compared to the control group. The current study provides important new information as to the trait functional changes in brain activity associated with long-term mindfulness meditation, as well as the state changes specifically associated with eyes-open open monitoring meditation techniques.

  4. Eating for Your Eyes

    Science.gov (United States)

    Stastny, Sherri Nordstrom; Garden-Robinson, Julie

    2011-01-01

    An educational program targeting older adults was developed to increase knowledge regarding nutrition and eye health. With age, the chance for eye disease increases, so prevention is critical. The Eating for Your Eyes program has promoted behavior changes regarding eye health among the participants. This program is easily replicated and use is…

  5. Comparative Case Study of Diffusion of Eye Movement Desensitization and Reprocessing in Two Clinical Settings : Empirically Supported Treatment Status Is Not Enough

    NARCIS (Netherlands)

    Cook, Joan M.; Biyanova, Tatyana; Coyne, James C.

    2009-01-01

    An in-depth comparative case study was conducted of two attempts at diffusion of an empirically supported, but controversial, psychotherapy: eye movement desensitization and reprocessing (EMDR). One Department of Veterans Affairs (VA) treatment setting in which there was substantial uptake was compa

  6. Comparative Case Study of Diffusion of Eye Movement Desensitization and Reprocessing in Two Clinical Settings: Empirically Supported Treatment Status Is Not Enough

    NARCIS (Netherlands)

    Cook, Joan M.; Biyanova, Tatyana; Coyne, James C.

    2009-01-01

    An in-depth comparative case study was conducted of two attempts at diffusion of an empirically supported, but controversial, psychotherapy: eye movement desensitization and reprocessing (EMDR). One Department of Veterans Affairs (VA) treatment setting in which there was substantial uptake was compa

  7. Does an eye-hand coordination test have added value as part of talent identification in table tennis? A validity and reproducibility study

    NARCIS (Netherlands)

    Faber, I.R.; Oosterveld, F.G.J.; Nijhuis-Van der Sanden, M.W.G.

    2014-01-01

    This study investigated the added value, i.e. discriminative and concurrent validity and reproducibility, of an eye-hand coordination test relevant to table tennis as part of talent identification. Forty-three table tennis players (7-12 years) from national (n = 13), regional (n = 11) and local trai

  8. Using Eye-Tracking to Study the On-Line Processing of Case-Marking Information among Intermediate L2 Learners of German

    Science.gov (United States)

    Jackson, Carrie N.; Dussias, Paola E.; Hristova, Adelina

    2012-01-01

    This study uses eye-tracking to examine the processing of case-marking information in ambiguous subject- and object-first wh-questions in German. The position of the lexical verb was also manipulated via verb tense to investigate whether verb location influences how intermediate L2 learners process L2 sentences. Results show that intermediate L2…

  9. Effects of Repetitive Transcranial Magnetic Stimulation in Performing Eye-Hand Integration Tasks: Four Preliminary Studies with Children Showing Low-Functioning Autism

    Science.gov (United States)

    Panerai, Simonetta; Tasca, Domenica; Lanuzza, Bartolo; Trubia, Grazia; Ferri, Raffaele; Musso, Sabrina; Alagona, Giovanna; Di Guardo, Giuseppe; Barone, Concetta; Gaglione, Maria P.; Elia, Maurizio

    2014-01-01

    This report, based on four studies with children with low-functioning autism, aimed at evaluating the effects of repetitive transcranial magnetic stimulation delivered on the left and right premotor cortices on eye-hand integration tasks; defining the long-lasting effects of high-frequency repetitive transcranial magnetic stimulation; and…

  10. Eye Movements and Reading Comprehension While Listening to Preferred and Non-Preferred Study Music

    Science.gov (United States)

    Johansson, Roger; Holmqvist, Kenneth; Mossberg, Frans; Lindgren, Magnus

    2012-01-01

    In the present study 24 university students read four different texts in four conditions: (1) while listening to music they preferred to listen to while studying; (2) while listening to music they did not prefer to listen to while studying; (3) while listening to a recording of noise from a cafe; and finally (4) in silence. After each text they…

  11. The effect of an eyes-closed dance-specific training program on dynamic balance in elite pre-professional ballet dancers: a randomized controlled pilot study.

    Science.gov (United States)

    Hutt, Kimberley; Redding, Emma

    2014-03-01

    Visual conditions for a dancer vary greatly between theatrical performance environments and dance studios, and this variability may be detrimental to their dynamic balance performance, particularly under stage lighting. In order to maintain balance control, dancers reportedly rely heavily on visual input, yet those who rely more on proprioceptive strategies for balancing have been found to be more stable. The purpose of this study was to assess the capability of an eyes-closed, dance-specific training program to nurture in dancers proprioceptive mechanisms that may facilitate their dynamic balance control. Eighteen elite pre-professional ballet dancers were randomly assigned to either a control (eyes open) or experimental (eyes closed) group for the intervention. The balance abilities of all subjects were tested using five dance-specific variations of the Star Excursion Balance Test before and after a 4 week balance intervention. Reach distance and time to complete the tests were recorded separately as indirect measurements of dynamic balance. The intervention consisted of dance-specific, eyes-closed exercises integrated into the dancers' daily ballet class and designed progressively to challenge the dancers' balance. During the intervention period, the control group undertook the same exercise program with their eyes open. Results revealed significant improvements in time to complete the three "timed" balance tests, and distances reached significantly improved in one of the two "reach" balance tests. No significant improvements were observed in the control group for any variation of the tests. These results indicate that dancers can be trained to adopt proprioceptive strategies to maintain dynamic balance, which consequently improves their balance performance. Such findings could encourage use of eyes-closed training in daily dance classes due to its potential to improve dancers' balance control.

  12. Co-morbidity of depression and anxiety in common age-related eye diseases: a population-based study of 662 adults.

    Science.gov (United States)

    Eramudugolla, Ranmalee; Wood, Joanne; Anstey, Kaarin J

    2013-01-01

    This study examined the prevalence of co-morbid age-related eye disease and symptoms of depression and anxiety in late life, and the relative roles of visual function and disease in explaining symptoms of depression and anxiety. A community-based sample of 662 individuals aged over 70 years was recruited through the electoral roll. Vision was measured using a battery of tests including high and low contrast visual acuity, contrast sensitivity, motion sensitivity, stereoacuity, Useful Field of View, and visual fields. Depression and anxiety symptoms were measured using the Goldberg scales. The prevalence of self-reported eye disease [cataract, glaucoma, or age-related macular degeneration (AMD)] in the sample was 43.4%, with 7.7% reporting more than one form of ocular pathology. Of those with no eye disease, 3.7% had clinically significant depressive symptoms. This rate was 6.7% among cataract patients, 4.3% among those with glaucoma, and 10.5% for AMD. Generalized linear models adjusting for demographics, general health, treatment, and disability examined self-reported eye disease and visual function as correlates of depression and anxiety. Depressive symptoms were associated with cataract only, AMD, comorbid eye diseases and reduced low contrast visual acuity. Anxiety was significantly associated with self-reported cataract, and reduced low contrast visual acuity, motion sensitivity and contrast sensitivity. We found no evidence for elevated rates of depressive or anxiety symptoms associated with self-reported glaucoma. The results support previous findings of high rates of depression and anxiety in cataract and AMD, and in addition show that mood and anxiety are associated with objective measures of visual function independently of self-reported eye disease. The findings have implications for the assessment and treatment of mental health in the context of late-life visual impairment.

  13. Morphological features in eyes with endophthalmitis after cataract surgery

    DEFF Research Database (Denmark)

    Solborg Bjerrum, Søren; Prause, Jan Ulrik; Fuchs, Helle Josefine

    2016-01-01

    PURPOSE: To assess the ocular damage that occurs in eyes with postoperative endophthalmitis after cataract surgery (PE) based on optical coherence tomography (OCT) retinal scans of PE eyes and histological specimens of eyes removed due to PE. METHODS: Case-control study and case series. Fifty......-one patients who had previously developed PE were clinically examined with OCT scans of the retina of both eyes. Histological specimens of 10 removed PE eyes were studied. RESULTS: The OCT scans showed that PE eyes had a statistically significantly higher frequency of hyperdense elements on the internal...... limiting membrane (ILM) of the retina (14 eyes versus 3 eyes, p = 0.015) and a higher degree of retinal atrophy temporal to the fovea (13 eyes versus 1 eye, p = 0.013) compared to fellow eyes. The histopathological analyses showed the formation of epiretinal membranes, derangement of all retinal layers...

  14. Effects of Long-Term Antiglaucoma Eye Drops on Conjunctival Structures: An In Vivo Confocal Microscopy Study

    Directory of Open Access Journals (Sweden)

    Wenqing Zhu

    2015-01-01

    Full Text Available Purpose. The study was aimed at comparing the long-term effects of different antiglaucoma eye drops on conjunctival structures using laser scanning confocal microscopy. Methods. Eighty patients diagnosed with primary open-angle glaucoma and twenty healthy volunteers were included in this study. The participants were divided into 5 groups according to the different medications. The lachrymal film break-up time, Schirmer’s I test, and Ocular Surface Disease Index Questionnaire were performed in all subjects. The confocal microscopy was used to observe the basal epithelial cell density (ECD, goblet cell density (GCD, dendritic cell density (DCD, and subepithelial collagen fiber diameter (SFD. Results. Statistically significant differences were found among the control group and the antiglaucoma therapy groups in the values of three clinical data (P<0.05. The GCD, DCD, and SFD showed significant differences in all glaucoma groups when compared to the control (P<0.001. Moreover, the prostaglandin group differed from the other antiglaucoma therapy groups in the GCD and SFD (P<0.05. Conclusions. Our study confirmed the significant differences in the conjunctival structures based on the effects of antiglaucoma medications. Less pronounced changes were found in the patients treated with prostaglandin analogue than in the other kinds of antiglaucoma therapies.

  15. Comparative Study of Sustained Attentional Bias on Emotional Processing in ADHD Children to Pictures with Eye-Tracking

    Directory of Open Access Journals (Sweden)

    Ebrahim PISHYAREH

    2015-01-01

    Full Text Available How to Cite This Article: Pishyareh E, Tehrani-doost M, Mahmoodi-gharaie J, Khorrami A, Rahmdar SR. A Comparative Study of SustainedAttentional Bias on Emotional Processing in ADHD Children to Pictures with Eye-Tracking. Iran J Child Neurol. 2015 Winter;9(1:64-70.AbstractObjectiveADHD children have anomalous and negative behavior especially in emotionally related fields when compared to other. Evidence indicates that attention has an impact on emotional processing. The present study evaluates the effect of emotional processing on the sustained attention of children with ADHD type C.Materials & Methods Sixty participants form two equal groups (each with 30 children of normal and ADHD children and each subject met the required selected criterion as either a normal or an ADHD child. Both groups were aged from 6–11-years-old. All pictures were chosen from the International Affective Picture System (IAPS and presented paired emotional and neutral scenes in the following categories: pleasant-neutral; pleasant-unpleasant; unpleasant-neutral; and neutral–neutral. Sustained attention was evaluated based on the number and duration of total fixation and was compared between the groups with MANOVA analysis.ResultsThe duration of sustained attention on pleasant in the pleasant-unpleasant pair was significant. Bias in duration of sustained attention on pleasant scenes in pleasant-neutral pairs is significantly different between the groups.ConclusionSuch significant differences might be indicative of ADHD children deficiencies in emotional processing. It seems that the highly deep effect of emotionally unpleasant scenes to gain the focus of ADHD children’s attention is responsible for impulsiveness and abnormal processing of emotional stimuli. References1. Sadock, B.J., H.I. Kaplan, and V.A. Sadock, Kaplan & Sadcok’s Synopsis of Psychiatry: Behavioral Sciences, Clinical Psychiatry. Lippincott; Williams & Wilkins. 2003.2. Cormier, E., Attention deficit

  16. A quantitative study of electroencephalography, eye movements and neck electromyography characterizing the sleep-wake cycle of the guinea-pig.

    Science.gov (United States)

    Escudero, M; Vidal, P P

    1996-03-01

    The qualitative and quantitative characteristics of cerebral cortex electrical activity, ocular motility and muscular activity were studied in six head-restrained guinea-pigs during wakefulness, slow-wave and paradoxical sleep. Animals were chronically implanted with bipolar electrodes in the obliquus capitis muscle for electromyographic recordings and epidurally through the parietal bones for electroencephalographic (EEG) recordings. Eye movements were recorded using the scleral search-coil technique. After postoperative recovery and a short period of habituation to immobilization, head-restrained animals exhibited a polyphasic sleep-wake cycle similar to what has already been described in the unrestrained guinea-pig. Paradoxical sleep periods of mean duration 110 +/- 42 s occurred at a mean interval of 32.2 +/- 7.2 min. Amplitude and frequency components of EEG activity were different for each state of vigilance. EEG amplitude was highest and frequency range lowest-with two well-defined peaks at 4 and 10 Hz-during slow-wave sleep. During paradoxical sleep, frequencies were higher and amplitudes lower than during wakefulness. Three types of eye movement intermingled with periods of ocular fixation were recorded: saccadic movements during wakefulness and paradoxical sleep, slow drifts during slow-wave sleep and paradoxical sleep, and a new type of eye movement-bursts of high-velocity eye oscillations during paradoxical sleep. Saccadic eye movements during paradoxical sleep were more frequent and showed higher velocities and amplitudes than during wakefulness. During paradoxical sleep the episodes of eye oscillation (8-14 Hz) occurred quite regularly every 1.6 s and had a mean duration of 1.4 s. During wakefulness, the obliquus muscle activity displayed a burst-tonic pattern. Bursting components were closely related to saccadic eye movements directed to the side of the recorded muscle. The muscle activity was predominantly tonic during slow-wave sleep and was

  17. Classroom Management through the Eyes of Elementary Teachers in Turkey: A Phenomenological Study

    Science.gov (United States)

    Akin, Sibel; Yildirim, Ali; Goodwin, A. Lin

    2016-01-01

    This study aims to explore Turkish elementary teachers' (1) perceptions of classroom management, (2) classroom management problems they experience, (3) factors causing these problems, and (4) their classroom management practices. The study employed phenomenological research design in the qualitative tradition. The participants included 15…

  18. University Organizational Culture through Insider Eyes: A Case Study of a Writing Program

    Science.gov (United States)

    Orton, Haley; Conley, Sharon

    2016-01-01

    Using a case study approach, the authors examined university administrator and instructor perspectives about a writing program's organizational culture. In so doing, members of the writing program were invited to participate in interviews over a three-year period. This qualitative case study suggests that examples of culture through a three-lens…

  19. The Role of Sketching States in the Stimulation of Idea Generation: An Eye Movement Study

    Science.gov (United States)

    Sun, Lingyun; Xiang, Wei; Yang, Cheng; Yang, Zhiyuan; Lou, Yun

    2014-01-01

    Sketching is widely used in design to generate creative ideas. Design studies present stimuli during sketching to enhance creativity. This study examines the effect of stimuli presented during different sketching states, especially of those presented during the stuck period. It conducted a sketching experiment that enrolled 41 students with an…

  20. Watching with New Eyes: Broadening the English Curriculum through Cinema Studies.

    Science.gov (United States)

    Chipman, Bruce

    One educator's interdisciplinary interests in literature, film, and culture studies led him to the establishment of "Film Study," an upper school English course in which students develop a sense of "film literacy" through detailed "reading" of visual images; in addition, students evolve a working critical vocabulary…

  1. Introduction of the Utrecht Tasks for Attention in Toddlers Using Eye Tracking (UTATE) : A Pilot Study

    NARCIS (Netherlands)

    de Jong, Marjanneke; Verhoeven, Marjolein; Hooge, Ignace T C; van Baar, Anneloes L

    2016-01-01

    Attention capacities underlie everyday functioning from an early age onwards. Little is known about attentional processes at toddler age. A feasible assessment of attention capacities at toddler age is needed to allow further study of attention development. In this study, a test battery is piloted t

  2. Differential effects of olanzapine and risperidone on cognition in schizophrenia? A saccadic eye movement study

    NARCIS (Netherlands)

    Broerse, A; Crawford, TJ; den Boer, JA

    2002-01-01

    Recent studies suggest that novel antipsychotics have positive effects on certain cognitive functions in schizophrenia. The present study investigated this claim by means of saccadic paradigms, which provide a selective index of cognitive function. Thirty-three first-episode schizophrenic patients w

  3. CLINICO - EPIDEMIOLOGICAL STUDY AND TREATMENT OUTCOME OF EALES’ DISEASE AT A TERTIARY EYE CARE HOSPITAL IN EASTERN INDIA

    Directory of Open Access Journals (Sweden)

    Bijnya Birajita

    2015-09-01

    Full Text Available BACKGROUND: Eales’ disease is an idiopathic inflammatory venous occlusion that primarily affects the peripheral retina of adults. Retinal changes include perivascular phlebitis, peripheral non - perfusion, and neovascularization. The prese nt - day modalities of treatment are confined to corticosteroids, anti - VEGF (Vasculo - endothelial growth factor therapy, and photocoagulation with or without anterior retinal cryoablation, and vitrectomy at various stages of the disease process. AIM : This study was conducted to study the age and sex distribution along with the mode of presentation of Eales disease. The natural course, aetiopathogenesis, treatment outcome in the study population was also studied. MATERIAL AND METHODS: In this descriptiv e study, 63 eyes of 37 newly diagnosed cases of Eales disease were enrolled. The demographic profile and clinical parameters of each patient were studied with special reference to place of origin, age and sex, mode of presentation, and treatment outcome. A ll patients underwent complete systemic and ophthalmologic examinations. Study patients were classified according to the stage of their disease and treated accordingly. RESULTS: Young males (21 - 30 years were mostly affected and 70% had bilateral presentat ion. 61% presented with symptoms related to posterior segment disease. Recorded best corrected visual acuity were 6/6 - 6/12 in 44.5%, 6/12 - 6/60 in 20% and <6/60 in 36.5%. 2 patients were kept on observation, 17 with medical treatment alone, 10 with photocoa gulation alone, 3 with photocoagulation and medical treatment and 5 were taken for vitreo - retinal surgery. Good visual recovery was observed in all subgroups at subsequent follow - up visits. CONCLUSION: As noted by this study, Eales disease is a disease mos tly in the young. These patients can present with no typical symptom or can be asymptomatic. Staging of the disease at presentation is important and correct treatment options should be

  4. NIH Study Provides Clarity on Supplements for Protection Against Blinding Eye Disease

    Science.gov (United States)

    ... are often referred to as dry AMD and wet AMD respectively. In a separate study, published online today ... a reduction in the number of neovascular, or wet, AMD cases—over the next five years, compared with ...

  5. Comprehensive eye evaluation algorithm

    Science.gov (United States)

    Agurto, C.; Nemeth, S.; Zamora, G.; Vahtel, M.; Soliz, P.; Barriga, S.

    2016-03-01

    In recent years, several research groups have developed automatic algorithms to detect diabetic retinopathy (DR) in individuals with diabetes (DM), using digital retinal images. Studies have indicated that diabetics have 1.5 times the annual risk of developing primary open angle glaucoma (POAG) as do people without DM. Moreover, DM patients have 1.8 times the risk for age-related macular degeneration (AMD). Although numerous investigators are developing automatic DR detection algorithms, there have been few successful efforts to create an automatic algorithm that can detect other ocular diseases, such as POAG and AMD. Consequently, our aim in the current study was to develop a comprehensive eye evaluation algorithm that not only detects DR in retinal images, but also automatically identifies glaucoma suspects and AMD by integrating other personal medical information with the retinal features. The proposed system is fully automatic and provides the likelihood of each of the three eye disease. The system was evaluated in two datasets of 104 and 88 diabetic cases. For each eye, we used two non-mydriatic digital color fundus photographs (macula and optic disc centered) and, when available, information about age, duration of diabetes, cataracts, hypertension, gender, and laboratory data. Our results show that the combination of multimodal features can increase the AUC by up to 5%, 7%, and 8% in the detection of AMD, DR, and glaucoma respectively. Marked improvement was achieved when laboratory results were combined with retinal image features.

  6. A Comparative Study on the Population Fitness of Three Strains of Nilaparvata lugens (Hemiptera: Delphacidae) Differ in Eye Color-Related Genes.

    Science.gov (United States)

    Liu, Shuhua; Yang, Baojun; Luo, Ju; Tang, Jian; Wu, Jincai

    2015-08-01

    The brown planthopper, Nilaparvata lugens (Stål), is a destructive insect pest on rice throughout Asia. As a visible genetic marker, red eye mutant colony of brown planthopper is a valuable material. Here, we established the near-isogenic lines, NIL-BB and NIL-rr, through mating red eye females to brown eye brothers for eight successive generations. Biological experiments showed that NIL-BB had big fitness cost; however, NIL-rr had comparable survival and fertility parameters with BB, a normal laboratory brown planthopper strain. Significantly lower number eggs per female and egg hatchability were the key factors resulting in big fitness cost of NIL-BB. The population trend indexes of BB, NIL-rr, and NIL-BB were 52.18, 43.80, and 4.19, respectively. Real-time PCR study suggested that the poorer fertility of NIL-BB was not mediated by the differential expression of genes relating to oogenesis. The stronger fitness of NIL-rr compared with NIL-BB may be caused by the eye mutant gene or its closely linked genes having stronger compensation ability for reproduction. The comparable fitness of NIL-rr with BB indicated that NIL-rr may be used in field research. The NIL-BB strain with significantly declined fecundity and survival ability can be used as study model for the signal pathways relating to fecundity.

  7. Preference for human eyes in human infants.

    Science.gov (United States)

    Dupierrix, Eve; de Boisferon, Anne Hillairet; Méary, David; Lee, Kang; Quinn, Paul C; Di Giorgio, Elisa; Simion, Francesca; Tomonaga, Masaki; Pascalis, Olivier

    2014-07-01

    Despite evidence supporting an early attraction to human faces, the nature of the face representation in neonates and its development during the first year after birth remain poorly understood. One suggestion is that an early preference for human faces reflects an attraction toward human eyes because human eyes are distinctive compared with other animals. In accord with this proposal, prior empirical studies have demonstrated the importance of the eye region in face processing in adults and infants. However, an attraction for the human eye has never been shown directly in infants. The current study aimed to investigate whether an attraction for human eyes would be present in newborns and older infants. With the use of a preferential looking time paradigm, newborns and 3-, 6-, 9-, and 12-month-olds were simultaneously presented with a pair of nonhuman primate faces (chimpanzees and Barbary macaques) that differed only by the eyes, thereby pairing a face with original nonhuman primate eyes with the same face in which the eyes were replaced by human eyes. Our results revealed that no preference was observed in newborns, but a preference for nonhuman primate faces with human eyes emerged from 3months of age and remained stable thereafter. The findings are discussed in terms of how a preference for human eyes may emerge during the first few months after birth.

  8. Seeing Chemistry through the Eyes of the Blind: A Case Study Examining Multiple Gas Law Representations

    Science.gov (United States)

    Harshman, Jordan; Bretz, Stacey Lowery; Yezierski, Ellen

    2013-01-01

    Adequately accommodating students who are blind or low-vision (BLV) in the sciences has been a focus of recent inquiry, but much of the research to date has addressed broad accommodations rather than devising and testing specific teaching strategies that respond to the unique challenges of BLV students learning chemistry. This case study seeks to…

  9. Eyes only? Perceiving eye contact is neither sufficient nor necessary for attentional capture by face direction.

    Science.gov (United States)

    Böckler, Anne; van der Wel, Robrecht P R D; Welsh, Timothy N

    2015-09-01

    Direct eye contact and motion onset both constitute powerful cues that capture attention. Recent research suggests that (social) gaze and (non-social) motion onset influence information processing in parallel, even when combined as sudden onset direct gaze cues (i.e., faces suddenly establishing eye contact). The present study investigated the role of eye visibility for attention capture by these sudden onset face cues. To this end, face direction was manipulated (away or towards onlooker) while faces had closed eyes (eliminating visibility of eyes, Experiment 1), wore sunglasses (eliminating visible eyes, but allowing for the expectation of eyes to be open, Experiment 2), and were inverted with visible eyes (disrupting the integration of eyes and faces, Experiment 3). Participants classified targets appearing on one of four faces. Initially, two faces were oriented towards participants and two faces were oriented away from participants. Simultaneous to target presentation, one averted face became directed and one directed face became averted. Attention capture by face direction (i.e., facilitation for faces directed towards participants) was absent when eyes were closed, but present when faces wore sunglasses. Sudden onset direct faces can, hence, induce attentional capture, even when lacking eye cues. Inverted faces, by contrast, did not elicit attentional capture. Thus, when eyes cannot be integrated into a holistic face representation they are not sufficient to capture attention. Overall, the results suggest that visibility of eyes is neither necessary nor sufficient for the sudden direct face effect.

  10. Eye and vision defects in under-five-year-old children in Oman: A public health intervention study

    Directory of Open Access Journals (Sweden)

    Rajiv Khandekar

    2010-01-01

    Result : Among 1,520 examined children, three children had absent eyeball bilaterally and three had unilaterally absent eyeball. Strabismus and nystagmus were detected in 44 (2.9% and 18 (1.2% children respectively. ′Hiding Heidi′ test was normal in 530/537 (87% of children. Distant vision reading was ≥0.32 in 386/448 (86.2% eyes. Preferential looking test suggested that half of the children had defective vision (>2cpcm. Screening at ′1-2 year′ and ′3-4 years′ age group could significantly predict eye problems ( P≤0.001. Conclusion : Eye and vision screening of under-five kids helped in detection of eye problems in early stages. Instead of universal screening, high risk population or children of ′3 to 4′ years for vision and ′1 to 2′ years for ocular abnormalities is proposed The existing health services could not detect some children with eye problems and they were identified during such screening.

  11. An exploratory study on the driving method of speech synthesis based on the human eye reading imaging data

    Science.gov (United States)

    Gao, Pei-pei; Liu, Feng

    2016-10-01

    With the development of information technology and artificial intelligence, speech synthesis plays a significant role in the fields of Human-Computer Interaction Techniques. However, the main problem of current speech synthesis techniques is lacking of naturalness and expressiveness so that it is not yet close to the standard of natural language. Another problem is that the human-computer interaction based on the speech synthesis is too monotonous to realize mechanism of user subjective drive. This thesis introduces the historical development of speech synthesis and summarizes the general process of this technique. It is pointed out that prosody generation module is an important part in the process of speech synthesis. On the basis of further research, using eye activity rules when reading to control and drive prosody generation was introduced as a new human-computer interaction method to enrich the synthetic form. In this article, the present situation of speech synthesis technology is reviewed in detail. Based on the premise of eye gaze data extraction, using eye movement signal in real-time driving, a speech synthesis method which can express the real speech rhythm of the speaker is proposed. That is, when reader is watching corpora with its eyes in silent reading, capture the reading information such as the eye gaze duration per prosodic unit, and establish a hierarchical prosodic pattern of duration model to determine the duration parameters of synthesized speech. At last, after the analysis, the feasibility of the above method is verified.

  12. Family Doctors Seen through the Eyes of Specialists: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Anna Probst

    2013-01-01

    Full Text Available Germany is facing a shortage of young family doctors. In search of possible reasons the aim of this study was to explore the perception of specialists on family doctors. Within a qualitative study 16 medical specialists from different fields in hospital and outpatient care setting were interviewed. Interviews were analysed using qualitative content analysis according to Mayring. Most of the interviewed specialists have a positive view on family doctors although a certain depreciative assumption is resonated in a number of statements. According to the specialists, family doctors enjoy a high status in public, even if social processes of change may have a negative influence on their rather old-fashioned image. Specialists find that family medicine is underrepresented in university education suffering from an upgrading of specialized disciplines. Altogether the majority of the interviewed specialists certify family doctors in Germany a positive image. Lecturer in medical education and training should be aware of their key role in the career choices of young trainees and avoid degradation or upgrading of certain medical disciplines. Interlinked measures on different levels focusing on the improvement of working conditions and representation at the universities would be needed to regain attractiveness for the family doctor's profession as a career choice for young doctors.

  13. Occupational eye dose in interventional cardiology procedures.

    Science.gov (United States)

    Haga, Yoshihiro; Chida, Koichi; Kaga, Yuji; Sota, Masahiro; Meguro, Taiichiro; Zuguchi, Masayuki

    2017-04-03

    It is important to measure the radiation dose [3-mm dose equivalent, Hp(3)] in the eye. This study was to determine the current occupational radiation eye dose of staff conducting interventional cardiology procedures, using a novel direct eye dosimeter. We measured the occupational eye dose [Hp(3)] in physicians and nurses in a catheterization laboratory for 6-months. The eye doses [Hp(3)] of 12 physicians (9 with Pb glasses, 3 without), and 11 nurses were recorded using a novel direct eye dosimeter, the DOSIRIS(TM). We placed dosimeters above and under the glasses. We also estimated the eye dose [0.07-mm dose equivalent] using a neck personal dosimeter. The eye doses among interventional staff ranked in the following order: physicians without Pb glasses > physicians with Pb glasses > nurses. The shielding effect of the glasses (0.07-mm Pb) in a clinical setting was approximately 60%. In physicians who do not wear Pb glasses, the eye dose may exceed the new regulatory limit for IR staff. We found good correlations between the neck dosimeter dose and eye dosimeter dose (inside or outside glasses, R(2) = 0.93 and R(2) = 0.86, respectively) in physicians. We recommend that interventional physicians use an eye dosimeter for correct evaluation of the lens dose.

  14. Eye Irritation Test of Bovis Calculus Pharmacopuncture Solutions for Eye Drop

    Directory of Open Access Journals (Sweden)

    Hyeong-sik Seo

    2008-06-01

    Full Text Available Objective : This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods : The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration (2005. 10. 21, KFDA 2005-60. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results : 1. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn’t physical problem at 9 rabbits. 2. After Bovis Calculus pharmacopuncture solutionwas medicated in the left eye of the rabbits, there wasn’t eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions : I suggested that Bovis Calculus pharmacopuncture solution didn’t induced eye irritation in rabbits.

  15. Ocular biometry in an urban Indian population: the Singapore Indian Eye Study (SINDI).

    Science.gov (United States)

    Pan, Chen-Wei; Wong, Tien-Yin; Chang, Lan; Lin, Xiao-Yu; Lavanya, Raghavan; Zheng, Ying-Feng; Kok, Yee-Onn; Wu, Ren-Yi; Aung, Tin; Saw, Seang-Mei

    2011-08-22

    PURPOSE. To describe the distribution and determinants of ocular biometric parameters in adult Singapore Indians. METHODS. A population-based, cross-sectional study was conducted on 3400 Indians aged 40 to 83 years residing in Singapore. Ocular components including axial length (AL), anterior chamber depth (ACD), and corneal radius (CR) were measured by partial coherence interferometry. Refraction was recorded in spherical equivalent (SE). RESULTS. After 502 individuals with previous cataract surgery were excluded, ocular biometric data on 2785 adults were analyzed. The mean AL, ACD, and CR were 23.45 ± 1.10, 3.15 ± 0.36, and 7.61 ± 0.26 mm, respectively. The mean AL/CR ratio was 3.08 ± 0.13. The mean AL was 23.53, 23.49, 23.35, and 23.25 mm in 40- to 49-, 50- to 59-, 60- to 69-, and 700 to 83-year age groups, respectively (P Singapore was similar to that of Malays in Singapore, but longer than that of Indians living in India. Time spent reading, height, and educational level were the strongest determinants of AL. AL was the strongest predictor of SE in all age groups.

  16. Through doctors' eyes: A qualitative study of hospital doctor perspectives on their working conditions.

    LENUS (Irish Health Repository)

    McGowan, Yvonne

    2013-03-11

    BACKGROUND: Hospital doctors face significant challenges in the current health care environment, working with staff shortages and cutbacks to health care expenditure, alongside increased demand for health care and increased public expectations. OBJECTIVE: This article analyses challenges faced by junior hospital doctors, providing insight into the experiences of these frontline staff in delivering health services in recessionary times. DESIGN: A qualitative methodology was chosen. METHODS: Semi-structured in-depth interviews were conducted with 20 doctors from urban Irish hospitals. Interviews were recorded via note taking. Full transcripts were analysed thematically using NVivo software. RESULTS: Dominant themes included the following: (1) unrealistic workloads: characterised by staff shortages, extended working hours, irregular and frequently interrupted breaks; (2) fatigue and its impact: the quality of care provided to patients while doctors were sleep-deprived was questioned; however, little reflection was given to any impact this may have had on junior doctors own health; (3) undervalued and disillusioned: insufficient training, intensive workloads and a perceived lack of power to influence change resulted in a sense of detachment among junior doctors. They appeared immune to their surroundings. CONCLUSION: Respondents ascribed little importance to the impact of current working conditions on their own health. They felt their roles were underappreciated and undervalued by policy makers and hospital management. Respondents were concerned with the lack of time and opportunity for training. This study highlighted several \\'red flags\\

  17. Interactions among emotional attention, encoding, and retrieval of ambiguous information: An eye-tracking study.

    Science.gov (United States)

    Everaert, Jonas; Koster, Ernst H W

    2015-10-01

    Emotional biases in attention modulate encoding of emotional material into long-term memory, but little is known about the role of such attentional biases during emotional memory retrieval. The present study investigated how emotional biases in memory are related to attentional allocation during retrieval. Forty-nine individuals encoded emotionally positive and negative meanings derived from ambiguous information and then searched their memory for encoded meanings in response to a set of retrieval cues. The remember/know/new procedure was used to classify memories as recollection-based or familiarity-based, and gaze behavior was monitored throughout the task to measure attentional allocation. We found that a bias in sustained attention during recollection-based, but not familiarity-based, retrieval predicted subsequent memory bias toward positive versus negative material following encoding. Thus, during emotional memory retrieval, attention affects controlled forms of retrieval (i.e., recollection) but does not modulate relatively automatic, familiarity-based retrieval. These findings enhance understanding of how distinct components of attention regulate the emotional content of memories. Implications for theoretical models and emotion regulation are discussed.

  18. A Retrospective Study of Causes of Low Vision in Saud Arabia, A Case of Eye World Medical Complex in Riyadh.

    Science.gov (United States)

    Z Alotaibi, Abdullah

    2015-10-20

    Vision is the ability of seeing with a definite understanding of features, color and contrast, and to distinguish between objects visually. In the year 1999, the World Health Organization (WHO) and the International Agency for the Prevention of Blindness formulated a worldwide project for the eradication of preventable loss of sight with the subject of "Vision 2020: the Right to Sight". This global program aims to eradicate preventable loss of sight by the year 2020. This study was conducted to determine the main causes of low vision in Saudi Arabia and also to assess their visual improvement after using low vision aids (LVD).The study is a retrospective study and was conducted in low vision clinic at Eye World Medical Complex in Riyadh, Saudi Arabia. The file medical record of 280 patients attending low vision clinics from February 2008 to June 2010 was included. A data sheet was filled which include: age, gender, cause of low vision, unassisted visual acuity for long distances and short distances, low vision devices needed for long distances and short distances that provides best visual acuity. The result shows that the main cause of low vision was Optic atrophy (28.9%). Retinitis pigmentosa was the second cause of low vision, accounting for 73 patients (26%) followed by Diabetic retinopathy and Macular degeneration with 44 patients (15.7%) and 16 patients (5.7%) respectively. Inter family marriage could be one of the main causes of low vision. Public awareness should be embarked on for enlightenment on ocular diseases result in consanguineous marriage. Also, it is an important issue to start establishing low vision clinics in order to improve the situation.

  19. Oral supplementation with a nutraceutical formulation containing omega-3 fatty acids, vitamins, minerals, and antioxidants in a large series of patients with dry eye symptoms: results of a prospective study

    Directory of Open Access Journals (Sweden)

    Gatell-Tortajada J

    2016-05-01

    Full Text Available Jordi Gatell-TortajadaOn behalf of the Large Dry Eye Clinical Study Group (LDECSGCornea and Ocular Surface Department, Institut Català de Retina, Barcelona, SpainPurpose: To assess the benefits and tolerability of a dietary supplement based on omega-3 fatty acids to relieve dry eye symptoms.Methods: A total of 1,419 patients (74.3% women, mean age 58.9 years with dry eye syndrome using artificial tears participated in a 12-week prospective study. Patients were instructed to take 3 capsules/day of the nutraceutical formulation (Brudysec® 1.5 g. Study variables were dry eye symptoms (scratchy and stinging sensation, eye redness, grittiness, painful and tired eyes, grating sensation, and blurry vision, conjunctival hyperemia, tear breakup time (TBUT, Schrimer I test, and Oxford grading scheme.Results: At 12 weeks, each dry eye symptom improved significantly (P<0.001, and the use of artificial tears decreased significantly from 3.77 (standard deviation [SD] =2.08 at baseline to 3.45 (SD =1.72 (P<0.01. In addition, the Schirmer test scores and the TBUT increased significantly, and there was an increase in patients grading 0–I in the Oxford scale and a decrease of those grading IV–V. Significant differences in improvements of dry eye symptoms were also found in compliant versus noncompliant patients as well as in those with moderate/severe versus none/mild conjunctival hyperemia.Conclusion: Oral ω-3 fatty acids supplementation was an effective treatment for dry eye symptoms.Keywords: dry eye symptoms, artificial tears, omega-3 polyunsaturated fatty acids, nutraceutical supplement, ocular inflammation, eye discomfort

  20. Social orienting of children with autism to facial expressions and speech: a study with a wearable eye-tracker in naturalistic settings

    OpenAIRE

    2013-01-01

    This study investigates attention orienting to social stimuli in children with Autism Spectrum Conditions (ASC) during dyadic social interactions taking place in real-life settings. We study the effect of social cues that differ in complexity and distinguish between social cues produced by facial expressions of emotion and those produced during speech. We record the children's gazes using a head-mounted eye-tracking device and report on a detailed and quantitative analysis of the motion...

  1. The effectiveness of eye movement desensitization and reprocessing (EMDR) in reducing pathological worry in patients with generalized anxiety disorder: a preliminary study

    OpenAIRE

    Farima Rezvani; Shiva Dowlatabadi; Safieh Behzadi

    2015-01-01

    Aim of the study The current study aimed to investigate the effectiveness of eye movement desensitization and reprocessing (EMDR) in reducing pathological worry in patients with generalized anxiety disorder (GAD). Subject or material and methods Method. Three women with GAD were selected using a purposeful sampling method based on the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I). A baseline single-case experimental design was used and participants were...

  2. A randomized crossover study comparing trehalose/hyaluronate eyedrops and standard treatment: patient satisfaction in the treatment of dry eye syndrome.

    Science.gov (United States)

    Pinto-Bonilla, Juan Carlos; Del Olmo-Jimeno, Alberto; Llovet-Osuna, Fernando; Hernández-Galilea, Emiliano

    2015-01-01

    Dry eye is a common disorder in routine ophthalmological practice, and a better understanding of the complex pathophysiology is leading to improved treatment. Thealoz Duo(®) is a novel artificial tear preparation containing two active ingredients: Trehalose, a naturally occurring disaccharide with anhydrobiotic functions in many organisms, and hyaluronate, a widely distributed anionic glycosaminoglycan polysaccharide with lubricative and water-retaining properties in biological systems. In a randomized, single center, open label, crossover study, 17 adult patients with moderate-to-severe dry eye syndrome were randomized to treatment with Thealoz Duo(®) (combining trehalose and hyaluronic acid) or Systane(®). Patients received 7 days of treatment. The primary efficacy variable was patient satisfaction evaluated by a 0-100 visual analog scale evaluated on days 0 and 7 of treatment. Secondary parameters included ocular surface disease index (OSDI), symptoms of dry eye, ocular staining scores (fluorescein and lissamine green), ocular clinical signs, Schirmer test, tear breakup time, and global efficacy assessed by the patient and the investigator. Seventeen patients were included. Patient satisfaction improved from 44.5±19.0 to 70.2±19.2 mm during Thealoz Duo(®) treatment and from 47.2±23 to 57.1±19.1 mm during Systane(®) treatment (P=0.043, mixed-effects analysis of covariance). Two secondary efficacy parameters (dry eye symptoms and the impact of their symptoms on work) showed statistically significant advantages for Thealoz Duo(®) over Systane(®). There were no statistically significant advantages for Systane(®) over Thealoz Duo(®) for any measured parameter. No adverse events were reported. Thealoz Duo(®) appears to be an effective combination of two active ingredients for the treatment of dry eye and is at least as effective as Systane(®).

  3. Sertraline and rapid eye movement sleep without atonia: an 8-week, open-label study of depressed patients.

    Science.gov (United States)

    Zhang, Bin; Hao, Yanli; Jia, Fujun; Tang, Yi; Li, Xueli; Liu, Wuhan; Arnulf, Isabelle

    2013-12-02

    Previous studies have reported that selective serotonin reuptake inhibitors (SSRIs) may induce or exacerbate rapid eye movement (REM) sleep without atonia (RSWA) and increase the risk of developing REM sleep behavior disorder (RBD). However, most of these studies are retrospective and cross-sectional and employed small sample sizes and a mixture of SSRIs. In this 8-week open-label trial of sertraline in depressed patients (n = 31), depressed patients were administered 50mg sertraline at 8 am on the 1st day and subsequently titrated up to a maximum of 200mg/day. All patients underwent repeated video-polysomnography (vPSG) (baseline, 1st day, 14th day, 28th day, and 56th day). Both tonic (submental) and phasic (submental and anterior tibialis) RSWA events were visually counted. Tonic RSWA increased from 3.2 ± 1.8% at baseline to 5.1 ± 2.3% on the 1st day and 10.4 ± 2.7% on the 14th day; after that, measurements were stable until the 56th day. A similar profile was observed for phasic RSWA. The increases in tonic RSWA (r = 0.56, P = 0.004) and phasic RSWA (submental: r = -0.51, P = 0.02; anterior tibialis: r = 0.41, P = 0.04) were correlated with the degree of the prolonging of REM latency. All of RSWAs were not correlated with patients' demographic and clinical characteristics. Sertraline may induce or exacerbate RSWA. In contrast to idiopathic RBD, sertraline-related RSWA had the specific characteristics of being correlated with the degree of the prolonging of REM latency and no predominance of male sex and elder age, suggesting different pathophysiological mechanisms. The antidepressant-related RSWA should be a potential public health problem in the depressed patients.

  4. How a hat may affect 3-month-olds' recognition of a face: an eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Hermann Bulf

    Full Text Available Recent studies have shown that infants' face recognition rests on a robust face representation that is resilient to a variety of facial transformations such as rotations in depth, motion, occlusion or deprivation of inner/outer features. Here, we investigated whether 3-month-old infants' ability to represent the invariant aspects of a face is affected by the presence of an external add-on element, i.e. a hat. Using a visual habituation task, three experiments were carried out in which face recognition was investigated by manipulating the presence/absence of a hat during face encoding (i.e. habituation phase and face recognition (i.e. test phase. An eye-tracker system was used to record the time infants spent looking at face-relevant information compared to the hat. The results showed that infants' face recognition was not affected by the presence of the external element when the type of the hat did not vary between the habituation and test phases, and when both the novel and the familiar face wore the same hat during the test phase (Experiment 1. Infants' ability to recognize the invariant aspects of a face was preserved also when the hat was absent in the habituation phase and the same hat was shown only during the test phase (Experiment 2. Conversely, when the novel face identity competed with a novel hat, the hat triggered the infants' attention, interfering with the recognition process and preventing the infants' preference for the novel face during the test phase (Experiment 3. Findings from the current study shed light on how faces and objects are processed when they are simultaneously presented in the same visual scene, contributing to an understanding of how infants respond to the multiple and composite information available in their surrounding environment.

  5. How a hat may affect 3-month-olds' recognition of a face: an eye-tracking study.

    Science.gov (United States)

    Bulf, Hermann; Valenza, Eloisa; Turati, Chiara

    2013-01-01

    Recent studies have shown that infants' face recognition rests on a robust face representation that is resilient to a variety of facial transformations such as rotations in depth, motion, occlusion or deprivation of inner/outer features. Here, we investigated whether 3-month-old infants' ability to represent the invariant aspects of a face is affected by the presence of an external add-on element, i.e. a hat. Using a visual habituation task, three experiments were carried out in which face recognition was investigated by manipulating the presence/absence of a hat during face encoding (i.e. habituation phase) and face recognition (i.e. test phase). An eye-tracker system was used to record the time infants spent looking at face-relevant information compared to the hat. The results showed that infants' face recognition was not affected by the presence of the external element when the type of the hat did not vary between the habituation and test phases, and when both the novel and the familiar face wore the same hat during the test phase (Experiment 1). Infants' ability to recognize the invariant aspects of a face was preserved also when the hat was absent in the habituation phase and the same hat was shown only during the test phase (Experiment 2). Conversely, when the novel face identity competed with a novel hat, the hat triggered the infants' attention, interfering with the recognition process and preventing the infants' preference for the novel face during the test phase (Experiment 3). Findings from the current study shed light on how faces and objects are processed when they are simultaneously presented in the same visual scene, contributing to an understanding of how infants respond to the multiple and composite information available in their surrounding environment.

  6. A Simple Method for Establishing Adherent Ex Vivo Explant Cultures from Human Eye Pathologies for Use in Subsequent Calcium Imaging and Inflammatory Studies

    Directory of Open Access Journals (Sweden)

    Sofija Andjelic

    2014-01-01

    Full Text Available A novel, simple, and reproducible method for cultivating pathological tissues obtained from human eyes during surgery was developed using viscoelastic material as a tissue adherent to facilitate cell attachment and expansion and calcium imaging of cultured cells challenged by mechanical and acetylcholine (ACh stimulation as well as inflammatory studies. Anterior lens capsule-lens epithelial cells (aLC-LECs from cataract surgery and proliferative diabetic retinopathy (PDR fibrovascular epiretinal membranes (fvERMs from human eyes were used in the study. We hereby show calcium signaling in aLC-LECs by mechanical and acetylcholine (ACh stimulation and indicate presence of ACh receptors in these cells. Furthermore, an ex vivo study model was established for measuring the inflammatory response in fvERMs and aLC-LECs upon TNFα treatment.

  7. Eye Drop Tips

    Science.gov (United States)

    ... Involved News About Us Donate In This Section Eye Drop Tips en Español email Send this article ... the reach of children. Steps For Putting In Eye Drops: Start by tilting your head backward while ...

  8. What Is Dry Eye?

    Medline Plus

    Full Text Available ... is also when your eyes do not make the right type of tears. How do tears work? ... you blink, a film of tears spreads over the eye. This keeps the eye’s surface smooth and ...

  9. Preventing eye injuries

    Directory of Open Access Journals (Sweden)

    Daksha Patel

    2016-01-01

    Full Text Available The main challenge in developing a strategy to prevent eye injuries is that there are so many different causes and situations that can lead to eye injuries, each requiring a different approach.

  10. Danish Rural Eye Study

    DEFF Research Database (Denmark)

    Høeg, Tracy Beth; Ellervik, Christina; Buch, Helena

    2016-01-01

    . The frequency of diabetes (HbA1c ≥ 48 mmol/mol or self-reported diagnosis) was 5.9% (n = 227), including 1.3% (n = 51) newly diagnosed in the GESUS. Of participants determined to have VI due to exudative AMD, 50% had received anti-vascular endothelial growth factor (VEGF) treatment. CONCLUSION: We report...

  11. Presence of collagen IV in the ciliary zonules of the human eye : An immunohistochemical study by LM and TEM

    NARCIS (Netherlands)

    Los, LI; van der Worp, RJ; van Luyn, MJA; Hooymans, JMM

    2004-01-01

    The ciliary zonules of the eye are composed of fibrillar and non-fibrillar components. Fibrils provide tensile strength and elasticity, whereas non-fibrillar components serve as a coating surrounding the fibrils. This coating behaves as a barrier to macromolecules. The present light and transmission

  12. Psychophysiological responsivity to script-driven imagery : an exploratory study of the effects of eye movements on public speaking flashforwards

    NARCIS (Netherlands)

    Kearns, M.; Engelhard, I.M.

    2015-01-01

    A principle characteristic of public speaking anxiety relates to intrusive mental images of potential future disasters. Previous research has found that the self-reported emotionality of such “flashforwards” can be reduced by a cognitively demanding, dual-task (e.g., making eye movements) performed

  13. Gaze Duration Biases for Colours in Combination with Dissonant and Consonant Sounds: A Comparative Eye-Tracking Study with Orangutans

    Science.gov (United States)

    Mühlenbeck, Cordelia; Liebal, Katja; Pritsch, Carla; Jacobsen, Thomas

    2015-01-01

    Research on colour preferences in humans and non-human primates suggests similar patterns of biases for and avoidance of specific colours, indicating that these colours are connected to a psychological reaction. Similarly, in the acoustic domain, approach reactions to consonant sounds (considered as positive) and avoidance reactions to dissonant sounds (considered as negative) have been found in human adults and children, and it has been demonstrated that non-human primates are able to discriminate between consonant and dissonant sounds. Yet it remains unclear whether the visual and acoustic approach–avoidance patterns remain consistent when both types of stimuli are combined, how they relate to and influence each other, and whether these are similar for humans and other primates. Therefore, to investigate whether gaze duration biases for colours are similar across primates and whether reactions to consonant and dissonant sounds cumulate with reactions to specific colours, we conducted an eye-tracking study in which we compared humans with one species of great apes, the orangutans. We presented four different colours either in isolation or in combination with consonant and dissonant sounds. We hypothesised that the viewing time for specific colours should be influenced by dissonant sounds and that previously existing avoidance behaviours with regard to colours should be intensified, reflecting their association with negative acoustic information. The results showed that the humans had constant gaze durations which were independent of the auditory stimulus, with a clear avoidance of yellow. In contrast, the orangutans did not show any clear gaze duration bias or avoidance of colours, and they were also not influenced by the auditory stimuli. In conclusion, our findings only partially support the previously identified pattern of biases for and avoidance of specific colours in humans and do not confirm such a pattern for orangutans. PMID:26466351

  14. Analysis of Attentional Bias towards Attractive and Unattractive Body Regions among Overweight Males and Females: An Eye-Movement Study

    Science.gov (United States)

    Warschburger, Petra; Calvano, Claudia; Richter, Eike M.; Engbert, Ralf

    2015-01-01

    Background Body image distortion is highly prevalent among overweight individuals. Whilst there is evidence that body-dissatisfied women and those suffering from disordered eating show a negative attentional bias towards their own unattractive body parts and others’ attractive body parts, little is known about visual attention patterns in the area of obesity and with respect to males. Since eating disorders and obesity share common features in terms of distorted body image and body dissatisfaction, the aim of this study was to examine whether overweight men and women show a similar attentional bias. Methods/Design We analyzed eye movements in 30 overweight individuals (18 females) and 28 normal-weight individuals (16 females) with respect to the participants’ own pictures as well as gender- and BMI-matched control pictures (front and back view). Additionally, we assessed body image and disordered eating using validated questionnaires. Discussion The overweight sample rated their own body as less attractive and showed a more disturbed body image. Contrary to our assumptions, they focused significantly longer on attractive compared to unattractive regions of both their own and the control body. For one’s own body, this was more pronounced for women. A higher weight status and more frequent body checking predicted attentional bias towards attractive body parts. We found that overweight adults exhibit an unexpected and stable pattern of selective attention, with a distinctive focus on their own attractive body regions despite higher levels of body dissatisfaction. This positive attentional bias may either be an indicator of a more pronounced pattern of attentional avoidance or a self-enhancing strategy. Further research is warranted to clarify these results. PMID:26479500

  15. Are numbers, size and brightness equally efficient in orienting visual attention? Evidence from an eye-tracking study.

    Science.gov (United States)

    Bulf, Hermann; Macchi Cassia, Viola; de Hevia, Maria Dolores

    2014-01-01

    A number of studies have shown strong relations between numbers and oriented spatial codes. For example, perceiving numbers causes spatial shifts of attention depending upon numbers' magnitude, in a way suggestive of a spatially oriented, mental representation of numbers. Here, we investigated whether this phenomenon extends to non-symbolic numbers, as well as to the processing of the continuous dimensions of size and brightness, exploring whether different quantitative dimensions are equally mapped onto space. After a numerical (symbolic Arabic digits or non-symbolic arrays of dots; Experiment 1) or a non-numerical cue (shapes of different size or brightness level; Experiment 2) was presented, participants' saccadic response to a target that could appear either on the left or the right side of the screen was registered using an automated eye-tracker system. Experiment 1 showed that, both in the case of Arabic digits and dot arrays, right targets were detected faster when preceded by large numbers, and left targets were detected faster when preceded by small numbers. Participants in Experiment 2 were faster at detecting right targets when cued by large-sized shapes and left targets when cued by small-sized shapes, whereas brightness cues did not modulate the detection of peripheral targets. These findings indicate that looking at a symbolic or a non-symbolic number induces attentional shifts to a peripheral region of space that is congruent with the numbers' relative position on a mental number line, and that a similar shift in visual attention is induced by looking at shapes of different size. More specifically, results suggest that, while the dimensions of number and size spontaneously map onto an oriented space, the dimension of brightness seems to be independent at a certain level of magnitude elaboration from the dimensions of spatial extent and number, indicating that not all continuous dimensions are equally mapped onto space.

  16. Are numbers, size and brightness equally efficient in orienting visual attention? Evidence from an eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Hermann Bulf

    Full Text Available A number of studies have shown strong relations between numbers and oriented spatial codes. For example, perceiving numbers causes spatial shifts of attention depending upon numbers' magnitude, in a way suggestive of a spatially oriented, mental representation of numbers. Here, we investigated whether this phenomenon extends to non-symbolic numbers, as well as to the processing of the continuous dimensions of size and brightness, exploring whether different quantitative dimensions are equally mapped onto space. After a numerical (symbolic Arabic digits or non-symbolic arrays of dots; Experiment 1 or a non-numerical cue (shapes of different size or brightness level; Experiment 2 was presented, participants' saccadic response to a target that could appear either on the left or the right side of the screen was registered using an automated eye-tracker system. Experiment 1 showed that, both in the case of Arabic digits and dot arrays, right targets were detected faster when preceded by large numbers, and left targets were detected faster when preceded by small numbers. Participants in Experiment 2 were faster at detecting right targets when cued by large-sized shapes and left targets when cued by small-sized shapes, whereas brightness cues did not modulate the detection of peripheral targets. These findings indicate that looking at a symbolic or a non-symbolic number induces attentional shifts to a peripheral region of space that is congruent with the numbers' relative position on a mental number line, and that a similar shift in visual attention is induced by looking at shapes of different size. More specifically, results suggest that, while the dimensions of number and size spontaneously map onto an oriented space, the dimension of brightness seems to be independent at a certain level of magnitude elaboration from the dimensions of spatial extent and number, indicating that not all continuous dimensions are equally mapped onto space.

  17. The all seeing eye?

    NARCIS (Netherlands)

    Koenderink, Jan J.

    2014-01-01

    The All Seeing Eye? Did you know that you are probably a believer in the All Seeing Eye? The odds are that I’m right—why? Well, the bulk of mainstream vision literature blindly relies on the All Seeing Eye. It is written all over papers, albeit between the lines. Understandably so, for scientists re

  18. About the Eye

    Medline Plus

    Full Text Available ... other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health ... Eye Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and ...

  19. The Eyes Are the Windows to the Mind: Direct Eye Gaze Triggers the Ascription of Others' Minds.

    Science.gov (United States)

    Khalid, Saara; Deska, Jason C; Hugenberg, Kurt

    2016-12-01

    Eye gaze is a potent source of social information with direct eye gaze signaling the desire to approach and averted eye gaze signaling avoidance. In the current work, we proposed that eye gaze signals whether or not to impute minds into others. Across four studies, we manipulated targets' eye gaze (i.e., direct vs. averted eye gaze) and measured explicit mind ascriptions (Study 1a, Study 1b, and Study 2) and beliefs about the likelihood of targets having mind (Study 3). In all four studies, we find novel evidence that the ascription of sophisticated humanlike minds to others is signaled by the display of direct eye gaze relative to averted eye gaze. Moreover, we provide evidence suggesting that this differential mentalization is due, at least in part, to beliefs that direct gaze targets are more likely to instigate social interaction. In short, eye contact triggers mind perception.

  20. Refractive error, visual acuity and causes of vision loss in children in Shandong, China. The Shandong Children Eye Study.

    Directory of Open Access Journals (Sweden)

    Jian Feng Wu

    Full Text Available PURPOSE: To examine the prevalence of refractive errors and prevalence and causes of vision loss among preschool and school children in East China. METHODS: Using a random cluster sampling in a cross-sectional school-based study design, children with an age of 4-18 years were selected from kindergartens, primary schools, and junior and senior high schools in the rural Guanxian County and the city of Weihai. All children underwent a complete ocular examination including measurement of uncorrected (UCVA and best corrected visual acuity (BCVA and auto-refractometry under cycloplegia. Myopia was defined as refractive error of ≤-0.5 diopters (D, high myopia as ≤ -6.0D, and amblyopia as BCVA ≤ 20/32 without any obvious reason for vision reduction and with strabismus or refractive errors as potential reasons. RESULTS: Out of 6364 eligible children, 6026 (94.7% children participated. Prevalence of myopia (overall: 36.9 ± 0.6%;95% confidence interval (CI:36.0,38.0 increased (P<0.001 from 1.7 ± 1.2% (95%CI:0.0,4.0 in the 4-years olds to 84.6 ± 3.2% (95%CI:78.0,91.0 in 17-years olds. Myopia was associated with older age (OR:1.56;95%CI:1.52,1.60;P<0.001, female gender (OR:1.22;95%CI:1.08,1.39;P = 0.002 and urban region (OR:2.88;95%CI:2.53,3.29;P<0.001. Prevalence of high myopia (2.0 ± 0.2% increased from 0.7 ± 0.3% (95%CI:0.1,1.3 in 10-years olds to 13.9 ± 3.0 (95%CI:7.8,19.9 in 17-years olds. It was associated with older age (OR:1.50;95%CI:1.41,1.60;P<0.001 and urban region (OR:3.11;95%CI:2.08,4.66;P<0.001. Astigmatism (≥ 0.75D (36.3 ± 0.6%;95%CI:35.0,38.0 was associated with older age (P<0.001;OR:1.06;95%CI:1.04,1.09, more myopic refractive error (P<0.001;OR:0.94;95%CI:0.91,0.97 and urban region (P<0.001;OR:1.47;95%CI:1.31,1.64. BCVA was ≤ 20/40 in the better eye in 19 (0.32% children. UCVA ≤ 20/40 in at least one eye was found in 2046 (34.05% children, with undercorrected refractive error as cause in 1975 (32.9% children. Amblyopia

  1. Changed processing of visual sexual stimuli under GnRH-therapy – a single case study in pedophilia using eye tracking and fMRI

    Science.gov (United States)

    2014-01-01

    experimental designs using eye tracking and fMRI could prospectively add additional and valuable information in the evaluation of ADT in paraphilic patients and sex offenders. But with respect to the limited significance of this single case study, these first results are preliminary and further studies have to be conducted with healthy subjects and patients. PMID:24885644

  2. Prevent Eye Injuries from Fireworks

    Science.gov (United States)

    ... Financial Assistance Information Vision Screening and Eye Exams Zika Virus and Vision Eye Problems Eye Problems Amblyopia ( ... Eye Health Report Reports and External Resources The Cost of Vision Problems The Future of Vision Vision ...

  3. Medicare Benefits and Your Eyes

    Science.gov (United States)

    ... Subscribe to eNews Close Donate Medicare Benefits & Your Eyes Eye Health is Important! As you age, your risk ... that you need. Ask about eye exams! Routine Eye Exams Medicare does not generally cover the costs ...

  4. Clinical study on high concentrations of sodium hyaluronate eye drops for moderate to severe dry eye%高浓度玻璃酸钠滴眼液治疗中重度干眼的临床研究

    Institute of Scientific and Technical Information of China (English)

    田玉景; 张钦

    2014-01-01

    AIM: To observe the efficacy of high concentrations of sodium hyaluronate ( 3g/L SH ) for moderate to severe dry eye. METHODS: Forty moderate to severe dry eye patients were included in the study according to the diagnosis criteria and randomized into two groups. The patients of the trial group received topical administration of high concentration sodium hyaluronate (3g/L), and those of the control group received sodium hyaluronate ( 1g/L ) plus recombinant human epidermal growth factor. The dry eye symptom scores, ocular surface disease index ( OSDI) scores, tear film break-up time ( BUT) , SchirmerⅠ test and corneal fluorescein staining score were evaluated. All the indexes were compared between the two groups 2wk before and after treatment. RESULTS: There were no significant differences of the indicators between the two groups before treatment. After 2wk treatment, the differences were statistically significant compared to former except for the SchirmerⅠtest. Compared with the control group, the symptom scores and the OSDI scores were lowered. No significant differences were found in the other indicators between these two groups. CONCLUSION: Topical usage of highconcentrations of sodium hyaluronate (3g/L) is beneficial for remitting the ocular symptoms in moderate to severe dry eyes, and also improve the quality of life of patients.%目的:观察高浓度玻璃酸钠滴眼液治疗中重度干眼的临床疗效。  方法:中重度干眼患者40例随机分成试验组和对照组,每组各20例。试验组用玻璃酸钠滴眼液(3g/L)、对照组玻璃酸钠滴眼液(1g/L)联合重组人表皮生长因子滴眼液治疗,治疗前和治疗2 wk后,通过症状评分、眼表疾病指数( OSDI)评分、泪膜破裂时间( BUT )、泪液分泌试验(Schirmer I test,SIt)、角膜荧光素染色评分(FL)等评价两组疗效。  结果:治疗前,两组各项指标差异均无统计学意义。治疗2 wk后,除SIt外,两组的其他指标和治

  5. Rapid eye movement sleep behavior disorder

    DEFF Research Database (Denmark)

    Schenck, C H; Montplaisir, J Y; Frauscher, B

    2013-01-01

    We aimed to provide a consensus statement by the International Rapid Eye Movement Sleep Behavior Disorder Study Group (IRBD-SG) on devising controlled active treatment studies in rapid eye movement sleep behavior disorder (RBD) and devising studies of neuroprotection against Parkinson disease (PD...

  6. Biomechanical modeling of eye trauma for different orbit anthropometries.

    Science.gov (United States)

    Weaver, Ashley A; Loftis, Kathryn L; Duma, Stefan M; Stitzel, Joel D

    2011-04-29

    In military, automotive, and sporting safety, there is concern over eye protection and the effects of facial anthropometry differences on risk of eye injury. The objective of this study is to investigate differences in orbital geometry and analyze their effect on eye impact injury. Clinical measurements of the orbital aperture, brow protrusion angle, eye protrusion, and the eye location within the orbit were used to develop a matrix of simulations. A finite element (FE) model of the orbit was developed from a computed tomography (CT) scan of an average male and transformed to model 27 different anthropometries. Impacts were modeled using an eye model incorporating lagrangian-eulerian fluid flow for the eye, representing a full eye for evaluation of omnidirectional impact and interaction with the orbit. Computational simulations of a Little League (CD25) baseball impact at 30.1m/s were conducted to assess the effect of orbit anthropometry on eye injury metrics. Parameters measured include stress and strain in the corneoscleral shell, internal dynamic eye pressure, and contact forces between the orbit, eye, and baseball. The location of peak stresses and strains was also assessed. Main effects and interaction effects identified in the statistical analysis illustrate the complex relationship between the anthropometric variation and eye response. The results of the study showed that the eye is more protected from impact with smaller orbital apertures, more brow protrusion, and less eye protrusion, provided that the orbital aperture is large enough to deter contact of the eye with the orbit.

  7. Age-Related Changes of Intraocular Pressure in Elderly People in Southern China: Lingtou Eye Cohort Study.

    Directory of Open Access Journals (Sweden)

    Xiaotong Han

    Full Text Available To study age-related changes of intraocular pressure (IOP and assess the cohort effect in both cross-sectional and longitudinal settings among elderly Chinese adults.Participants were enrolled from the Lingtou Eye Cohort Study with Chinese government officials aged 40 years and older at baseline and received physical check-up and ocular examinations from 2010 to 2012. IOP was measured using a non-contact tonometer according to standardized protocols, as well as systolic blood pressure (SBP, diastolic blood pressure (DBP and body mass index (BMI. Participants who had attended IOP measurements in both 2010 and 2012 were included in this study. Cross-sectional association of IOP with age was assessed using multivariate liner regression analyses and based on the data of 2010. Longitudinal changes in IOP were assessed by paired t-test.A total of 3372 subjects were enrolled in the current analysis (2010 mean [SD] age, 61.9 [7.1] years; 60.2% men. The mean IOP in 2010 was 15.4 ± 2.3 mmHg for women and 15.2 ± 2.3 mmHg for men with an intersex difference (P = 0.029. Cross-sectional analysis showed that IOP was negatively associated with age (P = 0.003, β = -0.033 for women and P<0.001, β = -0.061 for men adjusted for baseline SBP, DBP and BMI. Paired t-test suggested that IOP was higher in the year 2012 than 2010 in women (P = 0.006 but did not change significantly in men within 2 years (P = 0.345. In addition, the 2-year changes of IOP were not associated with age adjusted for baseline IOP in 2010 (P = 0.249.Cross-sectional data suggests that IOP is lower in people with older age. Longitudinal data does not support such findings and thus the identified decreasing pattern with age in cross-sectional analysis is likely caused by cohort effects.

  8. A randomized crossover study comparing trehalose/hyaluronate eyedrops and standard treatment: patient satisfaction in the treatment of dry eye syndrome

    Directory of Open Access Journals (Sweden)

    Pinto-Bonilla JC

    2015-04-01

    Full Text Available Juan Carlos Pinto-Bonilla,1 Alberto del Olmo-Jimeno,2 Fernando Llovet-Osuna,3 Emiliano Hernández-Galilea4 1Department of Corneal, Refractive, and Cataract Surgery, European Ophthalmological Institute, Clínica Baviera, Pamplona, Navarra, Spain; 2Optometry Department, European Ophthalmological Institute, Clínica Baviera, Pamplona, Navarra, Spain; 3Department of Refractive and Cataract Surgery, European Ophthalmological Institute, Clínica Baviera, Madrid, Madrid, Spain; 4Ophthalmology Department, Hospital Clínico Universitario de Salamanca, Universidad de Salamanca, Salamanca, Salamanca, Spain Abstract: Dry eye is a common disorder in routine ophthalmological practice, and a better understanding of the complex pathophysiology is leading to improved treatment. Thealoz Duo® is a novel artificial tear preparation containing two active ingredients: Trehalose, a naturally occurring disaccharide with anhydrobiotic functions in many organisms, and hyaluronate, a widely distributed anionic glycosaminoglycan polysaccharide with lubricative and water-retaining properties in biological systems. In a randomized, single center, open label, crossover study, 17 adult patients with moderate-to-severe dry eye syndrome were randomized to treatment with Thealoz Duo® (combining trehalose and hyaluronic acid or Systane®. Patients received 7 days of treatment. The primary efficacy variable was patient satisfaction evaluated by a 0–100 visual analog scale evaluated on days 0 and 7 of treatment. Secondary parameters included ocular surface disease index (OSDI, symptoms of dry eye, ocular staining scores (fluorescein and lissamine green, ocular clinical signs, Schirmer test, tear breakup time, and global efficacy assessed by the patient and the investigator. Seventeen patients were included. Patient satisfaction improved from 44.5±19.0 to 70.2±19.2 mm during Thealoz Duo® treatment and from 47.2±23 to 57.1±19.1 mm during Systane® treatment (P=0.043, mixed

  9. No association between nickel allergy and reporting cosmetic dermatitis from mascara or eye shadow: a cross-sectional general population study

    DEFF Research Database (Denmark)

    Thyssen, J P; Linneberg, A; Menné, T;

    2010-01-01

    dermatitis and nickel in make-up products remains controversial. OBJECTIVE: This cross-sectional patch test study investigated whether the frequency of self-reported cosmetic dermatitis from mascara or eye shadow use was higher among nickel allergic Danish women than women without nickel allergy. METHODS......: In 2006, a total of 1843 18-69 year old women completed a postal questionnaire including questions on cosmetic dermatitis and were patch tested with nickel sulphate. Data were analysed by logistic regression analyses and associations were expressed as odds ratios (ORs) with 95% confidence intervals (CIs......). RESULTS: The prevalence of nickel allergy was similar among women who reported cosmetic dermatitis from eye shadow or mascara and among women who did not report such symptoms. Cosmetic dermatitis was positively associated with self-reported atopic dermatitis and age. CONCLUSION: Overall, no association...

  10. How do design features influence consumer attention when looking for nutritional information on food labels? Results from an eye-tracking study on pan bread labels.

    Science.gov (United States)

    Antúnez, Lucía; Vidal, Leticia; Sapolinski, Alejandra; Giménez, Ana; Maiche, Alejandro; Ares, Gastón

    2013-08-01

    The aim of this work was to evaluate consumer visual processing of food labels when evaluating the salt content of pan bread labels and to study the influence of label design and nutritional labelling format on consumer attention. A total of 16 pan bread labels, designed according to a full factorial design, were presented to 52 participants, who were asked to decide whether the sodium content of each label was medium or low, while their eye movements were recorded using an eye tracker. Results showed that most participants looked at nutrition labels and the traffic light system to conclude on the salt content of the labels. However, the average percentage of participants who looked at the actual sodium content was much lower. Nutrition information format affected participants' processing of nutrition information. Among other effects, the inclusion of the traffic light system increased participants' attention towards some kind of nutrition information and facilitated its processing, but not its understanding.

  11. Zircon ages delimit the provenance of a sand extrudite from the Botucatu Formation in the Paraná volcanic province, Iraí, Brazil

    Directory of Open Access Journals (Sweden)

    VITER M. PINTO

    2015-09-01

    Full Text Available Ion microprobe age determinations of 102 detrital zircon crystals from a sand extrudite, Cretaceous Paraná volcanic province, set limits on the origin of the numerous sand layers present in this major flood basalt province. The zircon U-Pb ages reflect four main orogenic cycles: Mesoproterozoic (1155-962 Ma, latest Proterozoic-early Cambrian (808-500 Ma and two Palaeozoic (Ordovician- 480 to 450 Ma, and Permian to Lower Triassic- 296 to 250 Ma. Two additional small concentrations are present in the Neoarchean (2.8 to 2.6 Ga and Paleoproterozoic (2.0 to 1.7 Ga. Zircon age peaks closely match the several pulses of igneous activity in the Precambrian Brazilian Shield and active orogeny in Argentina. A main delimitation of the origin of the sand is the absence of zircon ages from the underlying Cretaceous basalts, thus supporting an injectite origin of the sand as an extrudite that emanated from the paleoerg that constitutes the Botucatu Formation.

  12. Internato de clínica médica em hospital secundário: a experiência da Faculdade de Medicina de Botucatu

    Directory of Open Access Journals (Sweden)

    Marcos F. Minicucci

    Full Text Available Na Faculdade de Medicina de Botucatu (FMB, os cursos de clínica médica (CM vêm sendo tradicionalmente ministrados nas enfermarias, ambulatórios, UTI e pronto-socorro do Hospital das Clínicas da FMB, sob a supervisão do Departamento de CM. Em outubro de 2002, a FMB passou a gerenciar o Hospital Estadual Bauru (HEB, tornando possível a transferência de parte do ensino de CM no internato para hospital secundário. Desde janeiro de 2004, grupos de internato, compostos por oito alunos, passaram a estagiar em enfermaria de clínica geral do HEB, sob a supervisão de preceptores da disciplina de CM geral. Entre as vantagens decorrentes dessa mudança, citamos a possibilidade de atender doentes com patologias mais simples, maior responsabilidade com o paciente, maior contato com o preceptor e o aprendizado sobre a necessidade de cumprir metas estabelecidas pelo hospital. A principal dificuldade na execução do estágio é a sobrecarga de trabalho para os preceptores, que é causada, em parte, pela ausência de residentes na enfermaria. Consideramos que a experiência em transferir parte do internato de CM para hospital secundário foi bem-sucedida e esta pode vir a estimular outras áreas da FMB para a busca de novos cenários de ensino.

  13. The impact of salience and visual working memory on the monitoring and control of saccadic behavior: An eye-tracking and EEG study.

    Science.gov (United States)

    Weaver, Matthew D; Hickey, Clayton; van Zoest, Wieske

    2017-01-10

    In a concurrent eye-tracking and EEG study, we investigated the impact of salience on the monitoring and control of eye movement behavior and the role of visual working memory (VWM) capacity in mediating this effect. Participants made eye movements to a unique line-segment target embedded in a search display also containing a unique distractor. Target and distractor salience was manipulated by varying degree of orientation offset from a homogenous background. VWM capacity was measured using a change-detection task. Results showed greater likelihood of incorrect saccades when the distractor was relatively more salient than when the target was salient. Misdirected saccades to salient distractors were strongly represented in the error-monitoring system by rapid and robust error-related negativity (ERN), which predicted a significant adjustment of oculomotor behavior. Misdirected saccades to less-salient distractors, while arguably representing larger errors, were not as well detected or utilized by the error/performance-monitoring system. This system was instead better engaged in tasks requiring greater cognitive control and by individuals with higher VWM capacity. Our findings show that relative salience of task-relevant and task-irrelevant stimuli can define situations where an increase in cognitive control is necessary, with individual differences in VWM capacity explaining significant variance in the degree of monitoring and control of goal-directed eye movement behavior. The present study supports a conflict-monitoring interpretation of the ERN, whereby the level of competition between different responses, and the stimuli that define these responses, was more important in the generation of an enhanced ERN than the error commission itself.

  14. Visual Impairment, Hearing Loss and Cognitive Function in an Older Population: Longitudinal Findings from the Blue Mountains Eye Study.

    Directory of Open Access Journals (Sweden)

    Thomas Hong

    Full Text Available The presence of visual impairment (VI and hearing loss (HL with may be a marker for subsequent cognitive decline over time in older people. A prospective, longitudinal population-based study of the 3654 participants of the Blue Mountains Eye Study were assessed for the associations between VI and HL and a decline in mini-mental state examination (MMSE scores over a duration of 10 years from the 5-year (baseline of this report to the 15-year follow-up visits. MMSE was assessed at the 5-, 10- and 15-year follow-up visits. A decline ≥3 scores from 5-year to 10- or 15-year visits indicated possible cognitive decline. VI was defined as best-corrected visual acuity 40 decibels in the worse-ear and dual sensory impairment (DSI was defined by the co-presence of VI and HL, detected at 5-year follow-up (baseline of this report. Participants with no VI and HL over the same 5- or 10-year corresponding period were controls. Associations of VI, HL and DSI with possible cognitive decline were assessed using logistic regression models adjusting for age and sex after excluding subjects with a stroke history. The presence of VI, HL or DSI was not associated with possible cognitive decline over 5 years (odds ratio (OR 0.84, 95% confidence-intervals (CI 0.40-1.79, OR 1.02, 95% CI 0.61-1.70 and 1.41, 95% CI 0.54-3.72, respectively or 10 years (OR 1.09, 95% CI 0.52-2.30, OR 1.09, 95% CI 0.65-1.82 and 1.15, 95% CI 0.28-4.73, respectively. There were no changes to these findings after adjustment for other potential confounders. Age was significantly associated with possible cognitive decline (OR 1.07, 95% CI 1.04-1.10 for both periods. Neither visual impairment, hearing loss nor dual sensory impairment was independently associated with subsequent decline in cognition.

  15. CLINICAL EVALUATION OF INTRASTROMAL VORICONAZOLE IN RECALCITRANT FUNGAL KERATITIS A PROSPECTIVE STUDY AT SAROJINI DEVI EYE HOSPITAL, HYDERABAD

    Directory of Open Access Journals (Sweden)

    Srinivas Prasad

    2015-07-01

    Full Text Available BACKGROUND: Recalcitrant Fungal keratitis is a common ocular infection leading to visual impairment. OBJECTIVES: To evaluate the efficacy of intrastromal Voriconazole in Recalcitrant Fungal keratitis. MATERIALS AND METHODS: This was an interventional study in department of Cornea, Sarojini Devi Eye Hospital, Osmania Medical College, Hyderabad over a period from Feb.2013 Feb.2014. 30 Patients of Fungal Keratitis not responding to routine topical and syst emic antifungal therapy in 7 to 14 days, which were diagnosed as Recalcitrant fungal keratitis were given 5μgms/0.1ml of voriconazole intrastroml injections around the fungal infiltrates in a grid pattern. Details of patients age and sex, type of causative fungal and traumatic agents, size of corneal ulcer, presence of Hypopyon or not, and time taken for hypopyon absorption, and clinical improvement and resolution of the ulcer and visual acuity were noted. RESULTS: This study group of 30 patients diagnosed as Recalcitrant fungal keratitis showed Causative Fungi as Fusarium in 19(63.0%, Aspergillus in 11(37.0%. Causative Traumatic Agents were vegetative matter i n 19 (63.3%, other agents in 8 (26.7% and not known in 3(10.0. 17(56.7% were Males with 13(43. 3% Females. Age wise distribution was 3(10.0% in>10 - 20yrs, 11(36.7% in 20 – 40 yrs, 15(50.0% in 40 - 60 yrs, and 1(3.3% in >60 yrs . The size of the ulcer showed 1/2 of the cornea in 9(30.0%. 19 (63.3% were with hy popyon and 11(36.7% without hypopyon . After Intrastromal Voriconazole, the absorption of Hypopyon in 12 (63.2% was in 2to 4 wks. and in 2(10.5% in > 4 wks. C linical improvement of the Fungal Corneal Ulcer was seen in no case (0.0% in 4 wks. Time (wks. of healing of the Fungal Corneal Ulcer was in 4 - 6wks in 21 (70.0% and in >6wks in 5(16.7%. Visual Acuity was <3/60 in 2(7.7%, 3/60 - <6/60 in 10(33.3%, 6/60 - <6/18 in 9(30.0% and 6/18 – 6/9 in 5(16.7 %. CONCLUSION: Common causes of fungal keratitis in Recalcitrant Fungal

  16. Eye tracking in Library and Information Science

    DEFF Research Database (Denmark)

    Lund, Haakon

    2016-01-01

    . Subsequently, a growing interest in employing eye tracking as a methodology within library and information science research must be anticipated. Design/methodology/approach The review follows the guidelines set in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations. Two......, the number of test persons and reports on the eye-tracking measures. Furthermore, this study will report which other methods were applied in combination with eye tracking. Findings The number of published research utilizing eye-tracking technologies within library and information science (LIS) is still......Purpose The purpose of this paper is to present a systematic literature review of the application of eye-tracking technology within the field of library and information science. Eye-tracking technology has now reached a level of maturity, which makes the use of the technology more accessible...

  17. EXPERIMENTAL STUDY OF INDIVIDUAL THERMOLUMINESCENT DOSEMETERS PERFORMANCES FOR MEASURING THE DOSE EQUIVALENTS IN SKIN AND EYE LENS

    Directory of Open Access Journals (Sweden)

    E. N. Sheleenkova

    2014-01-01

    Full Text Available The article gives a comparative analysis of existing and newly developed thermoluminescent detectors DTG-4, TTLD-580, TLD-1011(TM and DTVS-01 and dosemeters MKD-A and MKD-B for the purposes of individual dosimetric control of skin and eye lens exposure to radiation. The dependence of sensitivity of different thermoluminescent dosemeters, designed for dose equivalents measurements in skin and eye lens on the type (photons and ȕ-particles and energy of radiation was determined experimentally. There are conclusions about the limits of applicability of existing detectors and dosemeters under different radiation exposure conditions. The article evaluates the possibility of different dosimeter use for specific radiation exposure conditions.

  18. Development of a novel two color tracer perfusion technique for the hydrodynamic study of aqueous outflow in bovine eyes

    Institute of Scientific and Technical Information of China (English)

    ZHU Jing-yin; YE Wen; GONG Hai-yan

    2010-01-01

    Background Elevation of intraocular pressure is usually associated with primary open angle glaucoma and caused by increased outflow resistance. A two-color fluorescent tracer technique was developed to investigate the hydrodynamics of aqueous humor outflow with changing intraocular pressure within the same eye, to better understand the relationship between outflow facility and effective filtration area. Methods Eighteen enucleated bovine eyes were first perfused at 30 mmHg with Dulbecco's phosphate-buffered saline containing 5.5 mmol/L D-glucose. After a stable baseline facility, red fluorescent microspheres (0.5 μm, 0.002% v/v) were exchanged and perfused. Eyes in the one-color control group (n=6) were immediately perfused with fixative. In the experimental group (n=6), eyes were perfused with green tracer after intraocular pressure reduced to 7 mmHg, while in the two-color control group (n=6), eyes were perfused with green tracer with intraocular pressure remaining at 30 mmHg. All 12 eyes were then perfusion-fixed. Outflow facility was continuously recorded in all eyes. Confocal images were taken along the inner wall of the aqueous plexus and the percent of the effective filtration length (PEFL; length of inner wall exhibiting tracer labeling/total length of inner wall) was measured. The relationships between outflow facility and PEFL were analyzed statistically. Results No significant differences were found in baseline facilities (ulmin~(-1)·mmHg~(-1)) among the three groups (the experimental group: 0.93 0.12; the two-color control group: 0.90 0.19; the one-color control group: 0.98 0.13). In the experimental group, the outflow facility was significantly higher at 7 mmHg (4.29±1.01) than that at 30 mmHg (1.90±0.67, P <0.001), which corresponded to a significant increase in the PEFL at 7 mmHg (54.70±8.42) from that at 30 mmHg ((11.76±4.56)%, P<0.001). The PEFL labeled by red fluorescent microspheres in the experimental group ((11.76±4.56)%) showed no

  19. Optical study on the vision correction and supernormal vision based on the wave-front aberrations of human eye

    Institute of Scientific and Technical Information of China (English)

    MU GuoGuang; WANG ZhaoQi; LIU YongJi; QUAN Wei; WANG Yang; WANG Wei

    2007-01-01

    In this paper we present the recent research results in the field of vision correction and supernormal vision according to the actual measurements of the wave-front aberrations and the corneal surface topography, the clinical detection of the visual function and the laser corneal refractive surgery, and the optimization of the optical system. These include the features of the aberrations of human eye with different pupil sizes, different fields of view and temporal accommodation, the influence of the polychromatic illumination of the visible wavelength on the supernormal vision,and the effect of the existing laser corneal refractive surgery on the wave-front aberrations of the eye. It is shown that the wave-front aberration of human eye is of temporal variation and of synthesis with multi impact factors. To achieve supernormal vision, an optimum engineering data for the customized laser corneal surgery should be firstly acquired, which may involve the dynamic free-form optical surface. Although the myopia can be corrected by the laser in situ keratomileusis (LASlK) in a certain degree, it brings about negative effects under scotopic conditions.

  20. Optical study on the vision correction and supernormal vision based on the wave-front aberrations of human eye

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper we present the recent research results in the field of vision correction and supernormal vision according to the actual measurements of the wave-front aberrations and the corneal surface topography,the clinical detection of the visual function and the laser corneal refractive surgery,and the optimization of the optical system. These include the features of the aberrations of human eye with different pupil sizes,different fields of view and temporal accommodation,the influence of the polychromatic illumination of the visible wavelength on the supernormal vision,and the effect of the existing laser corneal refractive surgery on the wave-front ab-errations of the eye. It is shown that the wave-front aberration of human eye is of temporal variation and of synthesis with multi impact factors. To achieve super-normal vision,an optimum engineering data for the customized laser corneal sur-gery should be firstly acquired,which may involve the dynamic free-form optical surface. Although the myopia can be corrected by the laser in situ keratomileusis(LASIK) in a certain degree,it brings about negative effects under scotopic condi-tions.

  1. Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours

    DEFF Research Database (Denmark)

    Wang, Jinmei; Wu, Yazhen; Heegaard, Steffen;

    2011-01-01

    using antibodies against COX-2 was performed on paraffin sections of normal human eyes and selected eye tumours arising from cells expressing COX-2. Results: Cyclooxygenase-2 expression was found in various structures of the normal eye. Abundant expression was seen in the cornea, iris, ciliary body......Purpose: Cyclooxygenase-2 (COX-2) is an enzyme involved in neoplastic processes. The purpose of the present study is to investigate COX-2 expression in the normal human eye and the expression pattern in selected eye tumours involving COX-2 expressing cells. Methods: Immunohistochemical staining...... and retina. The COX-2 expression was less in tumours deriving from the ciliary epithelium and also in retinoblastoma. Conclusion: Cyclooxygenase-2 is constitutively expressed in normal human eyes. The expression of COX-2 is much lower in selected eye tumours involving COX-2 expressing cells....

  2. Eye gaze as relational evaluation: averted eye gaze leads to feelings of ostracism and relational devaluation.

    Science.gov (United States)

    Wirth, James H; Sacco, Donald F; Hugenberg, Kurt; Williams, Kipling D

    2010-07-01

    Eye gaze is often a signal of interest and, when noticed by others, leads to mutual and directional gaze. However, averting one's eye gaze toward an individual has the potential to convey a strong interpersonal evaluation. The averting of eye gaze is the most frequently used nonverbal cue to indicate the silent treatment, a form of ostracism. The authors argue that eye gaze can signal the relational value felt toward another person. In three studies, participants visualized interacting with an individual displaying averted or direct eye gaze. Compared to receiving direct eye contact, participants receiving averted eye gaze felt ostracized, signaled by thwarted basic need satisfaction, reduced explicit and implicit self-esteem, lowered relational value, and increased temptations to act aggressively toward the interaction partner.

  3. Differences between Dyslexic and Non-Dyslexic Children in the Performance of Phonological Visual-Auditory Recognition Tasks: An Eye-Tracking Study.

    Directory of Open Access Journals (Sweden)

    Aimé Tiadi

    Full Text Available The object of this study was to explore further phonological visual-auditory recognition tasks in a group of fifty-six healthy children (mean age: 9.9 ± 0.3 and to compare these data to those recorded in twenty-six age-matched dyslexic children (mean age: 9.8 ± 0.2. Eye movements from both eyes were recorded using an infrared video-oculography system (MobileEBT® e(ye BRAIN. The recognition task was performed under four conditions in which the target object was displayed either with phonologically unrelated objects (baseline condition, or with cohort or rhyme objects (cohort and rhyme conditions, respectively, or both together (rhyme + cohort condition. The percentage of the total time spent on the targets and the latency of the first saccade on the target were measured. Results in healthy children showed that the percentage of the total time spent in the baseline condition was significantly longer than in the other conditions, and that the latency of the first saccade in the cohort condition was significantly longer than in the other conditions; interestingly, the latency decreased significantly with the increasing age of the children. The developmental trend of phonological awareness was also observed in healthy children only. In contrast, we observed that for dyslexic children the total time spent on the target was similar in all four conditions tested, and also that they had similar latency values in both cohort and rhyme conditions. These findings suggest a different sensitivity to the phonological competitors between dyslexic and non-dyslexic children. Also, the eye-tracking technique provides online information about phonological awareness capabilities in children.

  4. Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.

    Science.gov (United States)

    Halder, G; Callaerts, P; Flister, S; Walldorf, U; Kloter, U; Gehring, W J

    1998-06-01

    The Drosophila Pax-6 gene eyeless acts high up in the genetic hierarchy involved in compound eye development and can direct the formation of extra eyes in ectopic locations. Here we identify sine oculis and eyes absent as two mediators of the eye-inducing activity of eyeless. We show that eyeless induces and requires the expression of both genes independently during extra eye development. During normal eye development, eyeless is expressed earlier than and is required for the expression of sine oculis and eyes absent, but not vice versa. Based on the results presented here and those of others, we propose a model in which eyeless induces the initial expression of both sine oculis and eyes absent in the eye disc. sine oculis and eyes absent then appear to participate in a positive feedback loop that regulates the expression of all three genes. In contrast to the regulatory interactions that occur in the developing eye disc, we also show that in the embryonic head, sine oculis acts in parallel to eyeless and twin of eyeless, a second Pax-6 gene from Drosophila. Recent studies in vertebrate systems indicate that the epistatic relationships among the corresponding vertebrate homologs are very similar to those observed in Drosophila.

  5. Nutrients for the aging eye

    Directory of Open Access Journals (Sweden)

    Rasmussen HM

    2013-06-01

    Full Text Available Helen M Rasmussen,1 Elizabeth J Johnson2 1Educational Studies, Lesley University, Cambridge, MA, USA; 2Carotenoid and Health Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA Abstract: The incidence of age-related eye diseases is expected to rise with the aging of the population. Oxidation and inflammation are implicated in the etiology of these diseases. There is evidence that dietary antioxidants and anti-inflammatories may provide benefit in decreasing the risk of age-related eye disease. Nutrients of interest are vitamins C and E, β-carotene, zinc, lutein, zeaxanthin, and the omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid. While a recent survey finds that among the baby boomers (45–65 years old, vision is the most important of the five senses, well over half of those surveyed were not aware of the important nutrients that play a key role in eye health. This is evident from a national survey that finds that intake of these key nutrients from dietary sources is below the recommendations or guidelines. Therefore, it is important to educate this population and to create an awareness of the nutrients and foods of particular interest in the prevention of age-related eye disease. Keywords: nutrition, aging, eye health

  6. Effectiveness and tolerability of dietary supplementation with a combination of omega-3 polyunsaturated fatty acids and antioxidants in the treatment of dry eye symptoms: results of a prospective study

    Directory of Open Access Journals (Sweden)

    Oleñik A

    2014-01-01

    Full Text Available Andrea OleñikOn behalf of the Dry Eye Clinical Study Group (DECSGOphthalmology Department, Fundación Jiménez Díaz, Madrid, SpainBackground: We assessed the effectiveness and tolerability of a dietary supplement based on the combination of omega-3 essential fatty acids and antioxidants on dry eye-related symptoms.Methods: A total of 905 patients (72% women, median age 60 years with dry eye syndrome and using artificial tears to relieve symptoms participated in an open-label prospective intervention study. They were recruited during a routine ophthalmological appointment. Patients were instructed to take three capsules/day of the nutraceutical formulation (Brudysec® 1.5 g for 12 weeks. Dry eye symptoms (categorized as 0, none; 1, mild; 2, moderate; and 3, severe included scratchy and stinging sensation in the eyes, eye redness, grittiness, painful eyes, tired eyes, grating sensation, and blurry vision.Results: The mean intensity of dry eye symptoms varied from 1.1 (± standard deviation [SD] 0.9 for painful eyes to 2.0 (0.9 for grittiness, with a mean value of 11.9 (4.8 for all symptoms together. At week 12, all individual symptoms improved significantly (P<0.001. The mean value for all symptoms together decreased from a mean value of 11.9 (± SD 4.8 at baseline to 6.8 (± SD 4.5 after 12 weeks of treatment (P<0.001. There was a decrease in the percentage of patients in which dry eye symptoms predominated nearly all the time (53.5% versus 34.1%. A total of 68.1% of patients reported better tolerance to contact lenses after treatment. The mean number of daily instillations of artificial tears also decreased significantly (3.8 [± SD 1.6] versus 3.3 [± SD 1.6], P<0.001. A total of 634 patients (70.1% did not report any adverse events. In the remaining patients with adverse events, the most frequent was fish-tasting regurgitation in 13.5% of cases, followed by nausea in 4.9%, diarrhea in 1.3%, and vomiting in 0.3%.Conclusion: Dietary

  7. Altered aquaporin expression in glaucoma eyes.

    Science.gov (United States)

    Tran, Thuy Linh; Bek, Toke; la Cour, Morten; Nielsen, Søren; Prause, Jan Ulrik; Hamann, Steffen; Heegaard, Steffen

    2014-09-01

    Aquaporins (AQP) are channels in the cell membrane that mainly facilitate a passive transport of water. In the eye, AQPs are expressed in the ciliary body and retina and may contribute to the pathogenesis of glaucoma and optic neuropathy. We investigated the expression of AQP1, AQP3, AQP4, AQP5, AQP7 and AQP9 in human glaucoma eyes compared with normal eyes. Nine glaucoma eyes were examined. Of these, three eyes were diagnosed with primary open angle glaucoma; three eyes had neovascular glaucoma; and three eyes had chronic angle-closure glaucoma. Six eyes with normal intraocular pressure and without glaucoma were used as control. Immunohistochemistry was performed using antibodies against AQP1, AQP3, AQP4, AQP5, AQP7 and AQP9. For each specimen, optical densities of immunoprecipitates were measured using Photoshop and the staining intensities were calculated. Immunostaining showed labelling of AQP7 and AQP9 in the nonpigmented ciliary epithelium and the staining intensities were significantly decreased in glaucoma eyes (p = 0.003; p = 0.018). AQP7 expression in the Müller cell endfeet was increased (p = 0.046), and AQP9 labelling of the retinal ganglion cells (RGC) showed decreased intensity (p = 0.037). No difference in AQP1, AQP4 and AQP9 expression was found in the optic nerve fibres. This study is the first investigating AQPs in human glaucoma eyes. We found a reduced expression of AQP9 in the retinal ganglion cells of glaucoma eyes. Glaucoma also induced increased AQP7 expression in the Müller cell endfeet. In the ciliary body of glaucoma eyes, the expression of AQP7 and AQP9 was reduced. Therefore, the expression of AQPs seems to play a role in glaucoma.

  8. Reading between eye saccades.

    Directory of Open Access Journals (Sweden)

    Caroline Blais

    Full Text Available BACKGROUND: Skilled adult readers, in contrast to beginners, show no or little increase in reading latencies as a function of the number of letters in words up to seven letters. The information extraction strategy underlying such efficiency in word identification is still largely unknown, and methods that allow tracking of the letter information extraction through time between eye saccades are needed to fully address this question. METHODOLOGY/PRINCIPAL FINDINGS: The present study examined the use of letter information during reading, by means of the Bubbles technique. Ten participants each read 5,000 five-letter French words sampled in space-time within a 200 ms window. On the temporal dimension, our results show that two moments are especially important during the information extraction process. On the spatial dimension, we found a bias for the upper half of words. We also show for the first time that letter positions four, one, and three are particularly important for the identification of five-letter words. CONCLUSIONS/SIGNIFICANCE: Our findings are consistent with either a partially parallel reading strategy or an optimal serial reading strategy. We show using computer simulations that this serial reading strategy predicts an absence of a word-length effect for words from four- to seven letters in length. We believe that the Bubbles technique will play an important role in further examining the nature of reading between eye saccades.

  9. A longitudinal cohort study of the impact of first- and both-eye cataract surgery on falls and other injuries in Vietnam

    Directory of Open Access Journals (Sweden)

    To KG

    2014-04-01

    Full Text Available Kien Gia To,1,2 Lynn Meuleners,1 Max Bulsara,3 Michelle L Fraser,1 Dat Van Duong,4 Dung Van Do,2 Van-Anh Ngoc Huynh,2 Tien Duy Phi,5 Hoang Huy Tran,5 Nguyen Do Nguyen51Curtin Monash Accident Research Centre (C-MARC, Faculty of Health Sciences, Curtin University, Perth, WA, Australia; 2University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam; 3Institute for Health Research, University of Notre Dame, Fremantle, WA, Australia; 4United Nations Population Fund, Hanoi, Vietnam; 5Eye Hospital, Ho Chi Minh City, VietnamAim: Little information exists on the impact of cataract surgery on falls and other injuries in Vietnam. The aim of this study was to determine the impact of first and both eye cataract surgery on the number of falls and other injuries among bilateral cataract patients in Ho Chi Minh City, Vietnam.Materials and methods: A longitudinal cohort study was conducted involving 413 bilateral cataract patients aged 50+ years. Participants were assessed at three time points: 1 week before, 1–3 months after, and 1 year after first-eye cataract surgery. Visual measures (visual acuity, contrast sensitivity and stereopsis were taken, and self-reported falls and injury data were collected. A multilevel longitudinal Poisson regression model was used to investigate change in the number of falls after surgery.Results: The risk of falls decreased by 78% (incidence-rate ratio [IRR] 0.22, 95% confidence interval [CI] 0.06–0.77; P=0.018 in the year after cataract surgery for participants who had first-eye surgery only and 83% (IRR 0.17, 95% CI 0.04–0.69; P=0.012 for participants who had the second eye operated on compared to before surgery. The risk of falls was three times higher for females than males (IRR 3.13, 95% CI 1.53–6.40; P=0.002. Improved binocular contrast sensitivity was also associated with a decrease in falls (IRR 0.40, 95% CI 0.17–0.97; P=0.042. The prevalence of other injuries also decreased after

  10. Maxwellian Eye Fixation during Natural Scene Perception

    Directory of Open Access Journals (Sweden)

    Jean Duchesne

    2012-01-01

    Full Text Available When we explore a visual scene, our eyes make saccades to jump rapidly from one area to another and fixate regions of interest to extract useful information. While the role of fixation eye movements in vision has been widely studied, their random nature has been a hitherto neglected issue. Here we conducted two experiments to examine the Maxwellian nature of eye movements during fixation. In Experiment 1, eight participants were asked to perform free viewing of natural scenes displayed on a computer screen while their eye movements were recorded. For each participant, the probability density function (PDF of eye movement amplitude during fixation obeyed the law established by Maxwell for describing molecule velocity in gas. Only the mean amplitude of eye movements varied with expertise, which was lower in experts than novice participants. In Experiment 2, two participants underwent fixed time, free viewing of natural scenes and of their scrambled version while their eye movements were recorded. Again, the PDF of eye movement amplitude during fixation obeyed Maxwell’s law for each participant and for each scene condition (normal or scrambled. The results suggest that eye fixation during natural scene perception describes a random motion regardless of top-down or of bottom-up processes.

  11. Yarbus, Eye Movements, and Vision

    Directory of Open Access Journals (Sweden)

    Benjamin W Tatler

    2010-04-01

    Full Text Available The impact of Yarbus's research on eye movements was enormous following the translation of his book Eye Movements and Vision into English in 1967. In stark contrast, the published material in English concerning his life is scant. We provide a brief biography of Yarbus and assess his impact on contemporary approaches to research on eye movements. While early interest in his work focused on his study of stabilised retinal images, more recently this has been replaced with interest in his work on the cognitive influences on scanning patterns. We extended his experiment on the effect of instructions on viewing a picture using a portrait of Yarbus rather than a painting. The results obtained broadly supported those found by Yarbus.

  12. Personal Identification by Eyes

    OpenAIRE

    Marinović, Dunja; Čoklo, Miran; Njirić, Sanja; Mužić, Vedrana

    2011-01-01

    Identification of persons through the eyes is in the field of biometrical science. Many security systems are based on biometric methods of personal identification, to determine whether a person is presenting itself truly. The human eye contains an extremely large number of individual characteristics that make it particularly suitable for the process of identifying a person. Today, the eye is considered to be one of the most reliable body parts for human identification. Systems usi...

  13. Infrared Eye: Prototype 2

    Science.gov (United States)

    2016-06-07

    within the wide field and slaved to the operator’s line of sight by means of an eye- tracking system. The images from both cameras are fused and shown...simultaneously on a high resolution CRT display unit, interfaced with the eye- tracking unit in order to optimize the human-machine interface. The IR Eye...system was flight tested using the Advanced system Research Aircraft (Bell 412 helicopter) from the Flight Research Laboratory of the National Research

  14. Teamwork for eye care

    Directory of Open Access Journals (Sweden)

    M Babar Qureshi

    2014-04-01

    Full Text Available Human resource development (HRD – the development of the people who deliver health care – has been identified as one of the key pillars of eye health delivery. HRD is one of the essential building blocks of the World Health Organization (WHO Global Action Plan: ‘Towards universal eye health’. The importance of HRD is also recognised beyond eye care, as can be seen in the WHO Health Systems approach.

  15. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Ophthalmology Education Center Oculofacial Plastic Surgery Center Laser Surgery Education Center Redmond Ethics ... Services Advocacy Foundation About Subspecialties & More Eye ...

  16. The Dragon Eyes the Top of the World: Arctic Policy Debate and Discussion in China (China Maritime Study, Number 8)

    Science.gov (United States)

    2011-08-01

    Strategy AMAP Arctic Monitoring and Assessment Program C CAA Canadian Arctic Archipelago CAFF Conservation of Arctic Flora and Fauna CCTV China Central...IM E S T U D IE S N o . 8 David Curtis Wright Number 8 The Dragon Eyes the Top of the World Arctic Policy Debate and Discussion in China Report...Discussion in China 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT

  17. Toddlers at High Risk of Chemical Eye Burns

    Science.gov (United States)

    ... fullstory_160258.html Toddlers at High Risk of Chemical Eye Burns: Study Access to household cleaning products to blame, ... and 2 years have relatively high rates of chemical eye burns, with everyday cleaners a common cause, researchers say. ...

  18. Mapeamento pedológico digital da folha Botucatu (SF-22-Z-B-VI-3: treinamento de dados em mapa tradicional e validação de campo

    Directory of Open Access Journals (Sweden)

    Cristiano Cassiano da Silva

    2013-08-01

    Full Text Available O mapeamento digital de solos permite prever padrões de ocorrência de solos com base em áreas de referência e no uso de técnicas de mineração de dados para modelar associações solo-paisagem. Os objetivos deste trabalho foram produzir um mapa pedológico digital por meio de técnicas de mineração de dados aplicadas a variáveis geomorfométricas e de geologia, com base em áreas de referência; e testar a confiabilidade desse mapa por meio de validação em campo com diferentes sistemas de amostragem. O mapeamento foi realizado na folha Botucatu (SF-22-Z-B-VI-3, utilizando-se as folhas 1:50.000, Dois Córregos e São Pedro, como áreas de referência. Variáveis descritoras do relevo e de geologia associadas às unidades de mapeamento pedológico das áreas de referência compuseram a matriz de dados de treinamento. A matriz foi analisada pelo algoritmo PART de árvore de decisão, do aplicativo Weka (Waikato Environment for Knowledge Analysis, que cria regras de classificação. Essas regras foram aplicadas aos dados geomorfométricos e geológicos da folha Botucatu, para predição de unidades de mapeamento pedológico. A validação de campo dos mapas digitais deu-se por meio de amostragem por transectos em uma unidade de mapeamento da folha São Pedro e de forma aleatório-estratificada na folha Botucatu. A avaliação da unidade de mapeamento na folha São Pedro verificou confiabilidade, respectivamente, de 83 e 66 %, para os mapas pedológicos digital e tradicional com legenda simplificada. Apesar de terem sido geradas regras para todas as unidades de mapeamento pedológico das áreas de treinamento, nem todas as unidades de mapeamento foram preditas na folha Botucatu, o que resultou das diferenças de relevo e geologia entre as áreas de treinamento e de mapeamento. A validação de campo do mapa digital da folha Botucatu verificou exatidão global de 52 %, compatível com levantamentos em nível de reconhecimento de baixa

  19. Pilot Study of the Delivery of Microcollimated Pars Plana External Beam Radiation in Porcine Eyes: 270-Day Analysis

    Directory of Open Access Journals (Sweden)

    Rishi P. Singh

    2012-01-01

    Full Text Available Objective. To determine the dose response and toxicity threshold of micro-collimated X-rays delivered to porcine maculae by a stereotactic radiosurgical system after 270 days. Methods. Twelve eyes of six Yucatan mini-swine were randomized to receive up to 90 Gy to the retina, using an office-based trans-pars plana delivery system. To determine the safety profile of this radiation delivery, ophthalmic examination, fundus photography, fluorescein angiography (FA, and spectral domain optical coherence tomography (SD-OCT were obtained at multiple time points up to 270 days post treatment. Results. No abnormalities were noted on external examination. Cataracts were noted in 4 of 12 eyes. Dose and time-dependent changes were noted on fundus examination, FA, ICG and SD-OCT. No significant abnormalities were seen in the control, 16 Gy or 24 Gy groups using any modality. Histopathology revealed a dose response effect with no discernable lesions in the 16 Gy group. Conclusion. The X-ray delivery system precisely targets the porcine retina in vivo with little effect on surrounding structures. No ophthalmic or intracranial adverse effects were noted at clinically relevant doses at 270 days following radiation delivery.

  20. An eye for the I: Preferential attention to the eyes of ingroup members.

    Science.gov (United States)

    Kawakami, Kerry; Williams, Amanda; Sidhu, David; Choma, Becky L; Rodriguez-Bailón, Rosa; Cañadas, Elena; Chung, Derek; Hugenberg, Kurt

    2014-07-01

    Human faces, and more specifically the eyes, play a crucial role in social and nonverbal communication because they signal valuable information about others. It is therefore surprising that few studies have investigated the impact of intergroup contexts and motivations on attention to the eyes of ingroup and outgroup members. Four experiments investigated differences in eye gaze to racial and novel ingroups using eye tracker technology. Whereas Studies 1 and 3 demonstrated that White participants attended more to the eyes of White compared to Black targets, Study 2 showed a similar pattern of attention to the eyes of novel ingroup and outgroup faces. Studies 3 and 4 also provided new evidence that eye gaze is flexible and can be meaningfully influenced by current motivations. Specifically, instructions to individuate specific social categories increased attention to the eyes of target group members. Furthermore, the latter experiments demonstrated that preferential attention to the eyes of ingroup members predicted important intergroup biases such as recognition of ingroup over outgroup faces (i.e., the own-race bias; Study 3) and willingness to interact with outgroup members (Study 4). The implication of these findings for general theorizing on face perception, individuation processes, and intergroup relations are discussed.

  1. Multiscale systems integration in the eye.

    Science.gov (United States)

    Jacobs, Marc D

    2009-01-01

    A series of research topics on the eye is reviewed with the aim of illustrating how integrative and systems-biological approaches can be used to understand complex properties and functions of ocular tissues. Emphasis is placed on the diversity of physiological systems represented in the eye, and the variety of approaches required to analyze those systems, both empirically and theoretically. Modeling and empirical studies reviewed focus mainly on problems that the eye presents, in the broad areas of biomechanics and fluid dynamics from the molecular to the whole-organ scale. Attention is given to the relevance of these studies in human disease and the current potential for development of medical therapies based upon a biophysical, integrative modeling approach. The creation of a multiscale hierarchy of numerical models of the eye is proposed as an important and unifying aim of integrative eye research.

  2. Fixations to the eyes aids in facial encoding; covertly attending to the eyes does not.

    Science.gov (United States)

    Laidlaw, Kaitlin E W; Kingstone, Alan

    2017-02-01

    When looking at images of faces, people will often focus their fixations on the eyes. It has previously been demonstrated that the eyes convey important information that may improve later facial recognition. Whether this advantage requires that the eyes be fixated, or merely attended to covertly (i.e. while looking elsewhere), is unclear from previous work. While attending to the eyes covertly without fixating them may be sufficient, the act of using overt attention to fixate the eyes may improve the processing of important details used for later recognition. In the present study, participants were shown a series of faces and, in Experiment 1, asked to attend to them normally while avoiding looking at either the eyes or, as a control, the mouth (overt attentional avoidance condition); or in Experiment 2 fixate the center of the face while covertly attending to either the eyes or the mouth (covert attention condition). After the first phase, participants were asked to perform an old/new face recognition task. We demonstrate that a) when fixations to the eyes are avoided during initial viewing then subsequent face discrimination suffers, and b) covert attention to the eyes alone is insufficient to improve face discrimination performance. Together, these findings demonstrate that fixating the eyes provides an encoding advantage that is not availed by covert attention alone.

  3. In the eye of the beholder: eye contact increases resistance to persuasion.

    Science.gov (United States)

    Chen, Frances S; Minson, Julia A; Schöne, Maren; Heinrichs, Markus

    2013-11-01

    Popular belief holds that eye contact increases the success of persuasive communication, and prior research suggests that speakers who direct their gaze more toward their listeners are perceived as more persuasive. In contrast, we demonstrate that more eye contact between the listener and speaker during persuasive communication predicts less attitude change in the direction advocated. In Study 1, participants freely watched videos of speakers expressing various views on controversial sociopolitical issues. Greater direct gaze at the speaker's eyes was associated with less attitude change in the direction advocated by the speaker. In Study 2, we instructed participants to look at either the eyes or the mouths of speakers presenting arguments counter to participants' own attitudes. Intentionally maintaining direct eye contact led to less persuasion than did gazing at the mouth. These findings suggest that efforts at increasing eye contact may be counterproductive across a variety of persuasion contexts.

  4. Perception of eye positions

    NARCIS (Netherlands)

    Lorteije, J.A.M.; Wezel, R.J.A. van; Lankheet, M.J.M.

    2002-01-01

    In a two-alternative forced-choice psychophysical test human subjects were tested for their ability to perceive their own viewing direction. A small red flash was presented at different horizontal positions left or right from the subjects' eye position on the screen. Eye positions were recorded with

  5. Understanding pink eye

    Science.gov (United States)

    Pink eye (PE) is a physiological tuber disorder that can result in serious processing complications and storage losses. The earliest external symptoms consist of an ephemeral pinkish discoloration around tuber eyes, predominately at the bud end of the tuber. These pinkish areas can then develop into...

  6. Why Do Eyes Water?

    Science.gov (United States)

    ... A Movies & More Quizzes Kids' Dictionary of Medical Words En Español What Other Kids Are Reading Taking Care of Your Ears Taking Care of Your Skin Taking Care of Your Teeth El cuidado de los dientes Video: Getting an X-ray Why Do Eyes Water? KidsHealth > For Kids > Why Do Eyes Water? Print ...

  7. BullsEye

    DEFF Research Database (Denmark)

    Klokmose, Clemens Nylandsted; Kristensen, Janus Bager; Bagge, Rolf

    2014-01-01

    implemented primarily in shaders on the GPU. The techniques are realized in the BullsEye computer vision software. We demonstrate experimentally that BullsEye provides sub-pixel accuracy down to a tenth of a pixel, which is a significant improvement compared to the commonly used reacTIVision software....

  8. Esparcialización horizontal de la evaporación en ambiente protegido – Botucatú, San Pablo- Brasil Horizontal spacialization of evaporation in protected environment in Botucatu - SP Espacialização horizontal da evaporação em ambiente protegido em Botucatu-SP

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius Wagner

    2009-12-01

    Full Text Available The management of irrigation water in a culture is important because it allows the rational use of this factor of production aimed at obtaining the maximum output per unit of water applied. Allied to this technology, the cultivation in protected environment enables continuous production at times of the year in which conditions are usually unfavorable to the field, allowing the supply of the domestic market in all seasons. The study was conducted in the experimental area of Department of Rural Engineering of the Paulista State University - UNESP, campus of Botucatu, to evaluate the spatial protected environment through the distribution of minievaporimeters to check the distribution of energy in three heights, 40, 80 and 120 cm from the ground and the horizontal specialization. The study was conducted in plastic greenhouse, with guidance Northwest-Southwest. The climatological variables, and the weekly evaporation of minievaporimeters were evaluated for 8 months. The results indicated that the spatial distribution of minievaporimeters showed that during the study period from 07th May to 16th July ocurred greater evaporation in the environment to 40 cm of soil, ie, during the coldest months. The period from July 30th to September 16th the highest evaporation occurred at 80 cm soil. The minievaporimeters installed to 120 cm of soil showed values less than or equal, in other times, regardless of the evaluation period. The west side of the environment had higher evaporation for the entire study period. There was more evaporation in the protected environment during the coldest months of the year for minievaporimeters which were near the ground.Saber aprovechar el manejo del agua al irrigar una cultura es muy importante una vez que permite utilizarla de forma racional lo que permite obtener una producción máxima para cada unidad de agua aplicada. Aliar esa tecnologia al cultivo en áreas de protección posibilita la producción contínua incluso en

  9. STP position paper: Recommended practices for sampling and processing the nervous system (brain, spinal cord, nerve, and eye) during nonclinical general toxicity studies.

    Science.gov (United States)

    Bolon, Brad; Garman, Robert H; Pardo, Ingrid D; Jensen, Karl; Sills, Robert C; Roulois, Aude; Radovsky, Ann; Bradley, Alys; Andrews-Jones, Lydia; Butt, Mark; Gumprecht, Laura

    2013-01-01

    The Society of Toxicologic Pathology charged a Nervous System Sampling Working Group with devising recommended practices to routinely screen the central nervous system (CNS) and peripheral nervous system (PNS) in Good Laboratory Practice-type nonclinical general toxicity studies. Brains should be weighed and trimmed similarly for all animals in a study. Certain structures should be sampled regularly: caudate/putamen, cerebellum, cerebral cortex, choroid plexus, eye (with optic nerve), hippocampus, hypothalamus, medulla oblongata, midbrain, nerve, olfactory bulb (rodents only), pons, spinal cord, and thalamus. Brain regions may be sampled bilaterally in rodents using 6 to 7 coronal sections, and unilaterally in nonrodents with 6 to 7 coronal hemisections. Spinal cord and nerves should be examined in transverse and longitudinal (or oblique) orientations. Most Working Group members considered immersion fixation in formalin (for CNS or PNS) or a solution containing acetic acid (for eye), paraffin embedding, and initial evaluation limited to hematoxylin and eosin (H&E)-stained sections to be acceptable for routine microscopic evaluation during general toxicity studies; other neurohistological methods may be undertaken if needed to better characterize H&E findings. Initial microscopic analyses should be qualitative and done with foreknowledge of treatments and doses (i.e., "unblinded"). The pathology report should clearly communicate structures that were assessed and methodological details. Since neuropathologic assessment is only one aspect of general toxicity studies, institutions should retain flexibility in customizing their sampling, processing, analytical, and reporting procedures as long as major neural targets are evaluated systematically.

  10. Driving with binocular visual field loss? A study on a supervised on-road parcours with simultaneous eye and head tracking.

    Directory of Open Access Journals (Sweden)

    Enkelejda Kasneci

    Full Text Available Post-chiasmal visual pathway lesions and glaucomatous optic neuropathy cause binocular visual field defects (VFDs that may critically interfere with quality of life and driving licensure. The aims of this study were (i to assess the on-road driving performance of patients suffering from binocular visual field loss using a dual-brake vehicle, and (ii to investigate the related compensatory mechanisms. A driving instructor, blinded to the participants' diagnosis, rated the driving performance (passed/failed of ten patients with homonymous visual field defects (HP, including four patients with right (HR and six patients with left homonymous visual field defects (HL, ten glaucoma patients (GP, and twenty age and gender-related ophthalmologically healthy control subjects (C during a 40-minute driving task on a pre-specified public on-road parcours. In order to investigate the subjects' visual exploration ability, eye movements were recorded by means of a mobile eye tracker. Two additional cameras were used to monitor the driving scene and record head and shoulder movements. Thus this study is novel as a quantitative assessment of eye movements and an additional evaluation of head and shoulder was performed. Six out of ten HP and four out of ten GP were rated as fit to drive by the driving instructor, despite their binocular visual field loss. Three out of 20 control subjects failed the on-road assessment. The extent of the visual field defect was of minor importance with regard to the driving performance. The site of the homonymous visual field defect (HVFD critically interfered with the driving ability: all failed HP subjects suffered from left homonymous visual field loss (HL due to right hemispheric lesions. Patients who failed the driving assessment had mainly difficulties with lane keeping and gap judgment ability. Patients who passed the test displayed different exploration patterns than those who failed. Patients who passed focused longer on

  11. Driving with binocular visual field loss? A study on a supervised on-road parcours with simultaneous eye and head tracking.

    Science.gov (United States)

    Kasneci, Enkelejda; Sippel, Katrin; Aehling, Kathrin; Heister, Martin; Rosenstiel, Wolfgang; Schiefer, Ulrich; Papageorgiou, Elena

    2014-01-01

    Post-chiasmal visual pathway lesions and glaucomatous optic neuropathy cause binocular visual field defects (VFDs) that may critically interfere with quality of life and driving licensure. The aims of this study were (i) to assess the on-road driving performance of patients suffering from binocular visual field loss using a dual-brake vehicle, and (ii) to investigate the related compensatory mechanisms. A driving instructor, blinded to the participants' diagnosis, rated the driving performance (passed/failed) of ten patients with homonymous visual field defects (HP), including four patients with right (HR) and six patients with left homonymous visual field defects (HL), ten glaucoma patients (GP), and twenty age and gender-related ophthalmologically healthy control subjects (C) during a 40-minute driving task on a pre-specified public on-road parcours. In order to investigate the subjects' visual exploration ability, eye movements were recorded by means of a mobile eye tracker. Two additional cameras were used to monitor the driving scene and record head and shoulder movements. Thus this study is novel as a quantitative assessment of eye movements and an additional evaluation of head and shoulder was performed. Six out of ten HP and four out of ten GP were rated as fit to drive by the driving instructor, despite their binocular visual field loss. Three out of 20 control subjects failed the on-road assessment. The extent of the visual field defect was of minor importance with regard to the driving performance. The site of the homonymous visual field defect (HVFD) critically interfered with the driving ability: all failed HP subjects suffered from left homonymous visual field loss (HL) due to right hemispheric lesions. Patients who failed the driving assessment had mainly difficulties with lane keeping and gap judgment ability. Patients who passed the test displayed different exploration patterns than those who failed. Patients who passed focused longer on the

  12. Análise de dados sócio-econômicos e sanitários de famílias residentes no distrito-sede de Botucatu (São Paulo, Brasil, em 1969 Socioeconomic and sanitary survey in families living in the Botucatu County (S. Paulo, Brazil in 1969

    Directory of Open Access Journals (Sweden)

    Maria Iraci Cabianca Ramos

    1973-06-01

    Full Text Available Foi realizado, em 1969, um levantamento de dados sócio-econômicos e sanitários da zona urbana de Botucatu. Trezentas e cinco famílias amostradas foram entrevistadas sobre: constituição familiar, idade, ocupação, renda, grau de instrução, condições sanitárias dos domicílios, conhecimento e uso de vacinas, demanda e opiniões relativas aos serviços de saúde. Algumas respostas foram associadas ao "status" sócio-econômico das famílias. As condições de saneamento básico estavam dentro de padrões quantitativos razoáveis e era alto o desconhecimento sobre o valor e número de doses das vacinas. Constatou-se acentuada dispersão de recursos para saúde, indicando falta de coordenação dos órgãos assistenciais; a demanda ao Centro de Saúde era baixa, quase restrita às crianças, indicando distorsão da percepção da comunidade com relação aos serviços médico-sanitários e necessidade de desenvolvimento adequado desses serviços, além de educação sanitária sistemática.In 1969, a survey was carried out concerning the socio-economical and sanitary aspects of the inhabitants in Botucatu County (S. Paulo, Brazil. Three hundred and five families were interviewed. Data involving the composition of the family, age of the memores, occupation, salary, sanitary conditions of their houses, knowledge about vaccination and their opinions about health services were collected and analysed. Some results were associated with the socioeconomic status of the families. The basic sanitation conditions were adequate and of reasonable standard. Knowledge about the value of vaccination as well as the required doses were vague Resources available for health were fragmented on indication of the lack of coordenation among the health services. Health centers were mainly sought for the care of children, on indication of the population's low degree of knowledge about their purposes. It was concluded that an improvement of the community viewpoints

  13. Occurrence of enteroparasites in day care centers in Botucatu (São Paulo State, Brazil with emphasis on Cryptosporidium sp., Giardia duodenalis and Enterobius vermicularis Ocorrência de enteroparasitas em creches de Botucatu (Estado de São Paulo, Brasil com ênfase em Cryptosporidium sp., Giardia duodenalis e Enterobius vermicularis

    Directory of Open Access Journals (Sweden)

    Thaís Batista de Carvalho

    2006-10-01

    Full Text Available The occurrence of the enteroparasites was verified in 279 children (0 to 6 years of four municipal day cares of Botucatu/SP. Three samples of each child's feces were collected and processed by the methods of Hoffman-Pons-Janner, Faust and Ritchie and subsequent coloration of the fecal smear by the methods of Auramina-O and Ziehl-Neelsen modified for diagnosis of Cryptosporidium sp. and Graham method for diagnosis of Enterobius vermicularis. Of the analyzed children we verified a prevalence of intestinal parasitism in 53.40%, and the most frequent parasite was Giardia duodenalis (26.88%. Significant association was verified among enteroparasitosis, family income, maternal education and age; the lowest enteroparasite frequency occurred in children of families with larger income and higher education. It was observed that G. duodenalis is more prevalent in children from 0 to 4 years and E. vermicularis is more frequent in children between three and four years old. The high enteroparasite prevalence in day cares suggests complex structure in its epidemiology, where factors beyond sanitation should be considered.Verificou-se a prevalência dos enteroparasitas em 279 crianças (0 a 6 anos de quatro creches municipais de Botucatu/SP. Foram coletadas três amostras de fezes de cada criança e processadas pelos métodos Hoffman, Faust e Ritchie e posterior coloração do esfregaço fecal pelos métodos de Auramina-O e Ziehl-Neelsen modificado para diagnóstico de Cryptosporidium sp. e método da fita gomada para diagnóstico de Enterobius vermicularis. Das crianças analisadas apresentaram-se parasitadas 53.40%, sendo que o parasita mais freqüente foi Giardia duodenalis (26.88%. Verificou-se associação significativa entre enteroparasitose, renda familiar, escolaridade materna e idade; quanto maior a renda e o grau escolar, menor a freqüência de enteroparasitas. Observou-se que G. duodenalis é mais prevalente em crianças de 0 a 4 anos e E

  14. Retina Image Analysis and Ocular Telehealth: The Oak Ridge National Laboratory-Hamilton Eye Institute Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Karnowski, Thomas Paul [ORNL; Giancardo, Luca [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Tobin Jr, Kenneth William [ORNL; Chaum, Edward [University of Tennessee, Knoxville (UTK)

    2013-01-01

    Automated retina image analysis has reached a high level of maturity in recent years, and thus the question of how validation is performed in these systems is beginning to grow in importance. One application of retina image analysis is in telemedicine, where an automated system could enable the automated detection of diabetic retinopathy and other eye diseases as a low-cost method for broad-based screening. In this work we discuss our experiences in developing a telemedical network for retina image analysis, including our progression from a manual diagnosis network to a more fully automated one. We pay special attention to how validations of our algorithm steps are performed, both using data from the telemedicine network and other public databases.

  15. Numerical abilities of school-age children with Developmental Coordination Disorder (DCD): A behavioral and eye-tracking study.

    Science.gov (United States)

    Gomez, Alice; Piazza, Manuela; Jobert, Antoinette; Dehaene-Lambertz, Ghislaine; Huron, Caroline

    2016-08-31

    Developmental Coordination Disorder (DCD) is a disorder of motor coordination which interferes with academic achievement. Difficulties in mathematics have been reported. Performance in the number line task is very sensitive to atypical development of numerical cognition. We used a position-to-number task in which twenty 7-to-10years old children with DCD and 20 age-matched typically developing (TD) children had to estimate the number that corresponded to a hatch mark placed on a 0-100 number line. Eye movements were recorded. Children with DCD were less accurate and slower to respond than their peers. However, they were able to map numbers onto space linearly and used anchoring strategies as control. We suggest that the shift to a linear trend reflects the ability of DCD children to use efficient strategies to solve the task despite a possibly more imprecise underlying numerical acuity.

  16. The eye-tracking of social stimuli in patients with Rett syndrome and autism spectrum disorders: a pilot study

    Directory of Open Access Journals (Sweden)

    José Salomão Schwartzman

    2015-05-01

    Full Text Available Objective To compare visual fixation at social stimuli in Rett syndrome (RT and autism spectrum disorders (ASD patients. Method Visual fixation at social stimuli was analyzed in 14 RS female patients (age range 4-30 years, 11 ASD male patients (age range 4-20 years, and 17 children with typical development (TD. Patients were exposed to three different pictures (two of human faces and one with social and non-social stimuli presented for 8 seconds each on the screen of a computer attached to an eye-tracker equipment. Results Percentage of visual fixation at social stimuli was significantly higher in the RS group compared to ASD and even to TD groups. Conclusion Visual fixation at social stimuli seems to be one more endophenotype making RS to be very different from ASD.

  17. The Relationship between Crystalline Lens Power and Refractive Error in Older Chinese Adults: The Shanghai Eye Study

    Science.gov (United States)

    He, Jiangnan; Lu, Lina; He, Xiangui; Xu, Xian; Du, Xuan; Zhang, Bo; Zhao, Huijuan; Sha, Jida; Zhu, Jianfeng; Zou, Haidong; Xu, Xun

    2017-01-01

    Purpose To report calculated crystalline lens power and describe the distribution of ocular biometry and its association with refractive error in older Chinese adults. Methods Random clustering sampling was used to identify adults aged 50 years and above in Xuhui and Baoshan districts of Shanghai. Refraction was determined by subjective refraction that achieved the best corrected vision based on monocular measurement. Ocular biometry was measured by IOL Master. The crystalline lens power of right eyes was calculated using modified Bennett-Rabbetts formula. Results We analyzed 6099 normal phakic right eyes. The mean crystalline lens power was 20.34 ± 2.24D (range: 13.40–36.08). Lens power, spherical equivalent, and anterior chamber depth changed linearly with age; however, axial length, corneal power and AL/CR ratio did not vary with age. The overall prevalence of hyperopia, myopia, and high myopia was 48.48% (95% CI: 47.23%–49.74%), 22.82% (95% CI: 21.77%–23.88%), and 4.57% (95% CI: 4.05–5.10), respectively. The prevalence of hyperopia increased linearly with age while lens power decreased with age. In multivariate models, refractive error was strongly correlated with axial length, lens power, corneal power, and anterior chamber depth; refractive error was slightly correlated with best corrected visual acuity, age and sex. Conclusion Lens power, hyperopia, and spherical equivalent changed linearly with age; Moreover, the continuous loss of lens power produced hyperopic shifts in refraction in subjects aged more than 50 years. PMID:28114313

  18. High Numerates Count Icons and Low Numerates Process Large Areas in Pictographs: Results of an Eye-Tracking Study.

    Science.gov (United States)

    Kreuzmair, Christina; Siegrist, Michael; Keller, Carmen

    2016-08-01

    In two experiments, we investigated the influence of numeracy on individuals' information processing of pictographs depending on numeracy via an eye-tracker. In two conditions, participants from the general population were presented with a scenario depicting the risk of having cancer and were asked to indicate their perceived risk. The risk level was high (63%) in experiment 1 (N = 70) and low (6%) in experiment 2 (N = 69). In the default condition, participants were free to use their default strategy for information processing. In the guiding-toward-the-number condition, they were prompted to count icons in the pictograph by answering with an explicit number. We used eye-tracking parameters related to the distance between sequential fixations to analyze participants' strategies for processing numerical information. In the default condition, the higher the numeracy was, the shorter the distances traversed in the pictograph were, indicating that participants counted the icons. People lower in numeracy performed increased large-area processing by comparing highlighted and nonhighlighted parts of the pictograph. In the guiding-toward-the-number condition, participants used short distances regardless of their numeracy, supporting the notion that short distances represent counting. Despite the different default processing strategies, participants processed the pictograph with a similar depth and derived similar risk perceptions. The results show that pictographs are beneficial for communicating medical risk. Pictographs make the gist salient by making the part-to-whole relationship visually available, and they facilitate low numerates' non-numeric processing of numerical information. Contemporaneously, pictographs allow high numerates to numerically process and rely on the number depicted in the pictograph.

  19. 基于视频的人眼跟踪方法研究%Study of the Eye-tracking Methods Based on Video

    Institute of Scientific and Technical Information of China (English)

    刘纪红; 李中帆

    2012-01-01

    Driver fatigue is one of the chief causes of traffic accident. Detecting and tracking driver's eyes effectively and exactly and in real-time is one of the key technologies in the system for detecting driver fatigue. This paper studies the eye-tracking methods in the images with the driver's face based on video. Firstly, a Haar cascade classifier for the face is designed by applying Viola-Jones arithmetic and AdaBoost arithmetic. Then the eye tracking is realized by two-step location methods. The experimental results shows that the methods presented in this paper are accurate and robust.%疲劳驾驶是交通事故发生的主要原因之一.在车载的驾驶员疲劳检测系统中,对于人眼的高效、实时、准确检测和跟踪是关键技术之一.本文研究基于视频信息的驾驶员人脸图像中眼睛的跟踪方法.采用Viola-Jones算法和AdaBoost算法设计了Haar级联人脸分类器,根据人脸的几何结构和眼睛的特性,通过两次定位的方法实现了对眼睛的定位和跟踪.实验表明,本文方法具有检测精度高、鲁棒性强的特点.

  20. A microstructural study of sleep instability in drug-naive patients with schizophrenia and healthy controls: sleep spindles, rapid eye movements, and muscle atonia.

    Science.gov (United States)

    Guénolé, Fabian; Chevrier, Elyse; Stip, Emmanuel; Godbout, Roger

    2014-05-01

    This study aimed at characterizing the functional stability of sleep in schizophrenia by quantifying dissociated stages of sleep (DSS), and to explore their correlation with psychopathology. The sleep of 10 first-break, drug-naive young adults with schizophrenia and 10 controls was recorded. Four basic DSS patterns were scored: 1) the transitional EEG-mixed intermediate stage (EMIS); 2) Rapid-eye-movement (REM) sleep without rapid eye movement (RSWR); 3) REM sleep without atonia (RSWA); and 4) non-REM sleep with rapid eye movements. An intermediate sleep (IS) score was calculated by summing EMIS and RSWR scores, and the durations of intra-REM sleep periods IS (IRSPIS) and IS scored "at the expense" of REM sleep (ISERS) were determined. Patients were administered the Brief Psychiatric Rating Scale (BPRS) at the time of recording. Proportions of each DSS variables over total sleep time and proportions of IRSPIS and ISERS over REM sleep duration were compared between patients and controls. Correlation coefficients between DSS variables and BPRS total scores were calculated. The proportion of total DSS did not differ between patients and controls. Among DSS subtypes, RSWA was significantly increased in patients while other comparisons showed no significant differences. Significant positive correlations were found between BPRS scores and proportions of DSS, IS, RSWR, IRSPIS and ISERS over total sleep and REM sleep durations. These results demonstrate the functional instability of REM sleep in first-break, drug naive young adults with schizophrenia and unveil a pattern reminiscent of REM sleep behavior disorder. The significant correlation suggests that schizophrenia and REM sleep share common neuronal control mechanisms.

  1. Therapy of corneal erosions and 'dry eye' with Solcoseryl and Vitasic eye drops.

    Science.gov (United States)

    Krannig, H M; Rohde-Germann, H; Straub, W

    1989-01-01

    A comparative study of Solcoseryl eye drops versus Vitasic eye drops has been carried out under controlled conditions (randomized and double-blind) on a total of 94 patients. 52 had corneal erosion, 30 had dry eye syndrome, 8 cases could not be evaluated. In addition, 2 eyes with photophthalmia were treated with Vitasic and 2 showing keratitis with Solcoseryl. There were no adverse reactions other than 2 instances of stinging with Solcoseryl and 1 case of severe irritation after Vitasic. The patients were examined on days 0, 1, 3 and 7. Results showed a consistent superiority of Solcoseryl eye drops in respect to speed of healing of corneal erosions and moistening of the cornea in the 'dry eye' syndrome which reached statistical significance in some parameters.

  2. Eye Tracking: A Brief Guide for Developmental Researchers

    Science.gov (United States)

    Feng, Gary

    2011-01-01

    Eye tracking offers a powerful research tool for developmental scientists. In this brief article, the author introduces the methodology and issues associated with its applications in developmental research, beginning with an overview of eye movements and eye-tracking technologies, followed by examples of how it is used to study the developing mind…

  3. Application of the Biospeckle Method for Monitoring Bull’s Eye Rot Development and Quality Changes of Apples Subjected to Various Storage Methods—Preliminary Studies

    Directory of Open Access Journals (Sweden)

    Krzysztof Rutkowski

    2012-03-01

    Full Text Available In this study, the biospeckle technique was evaluated for monitoring of apple bull’s eye rot development and product quality in general, during storage under various conditions and during subsequent shelf life. This non-destructive optical method is based on the analysis of laser light variations scattered from the sample. Apples of the cultivars ‘Pinova’ and ‘Topaz’, susceptible to bull’s eye rot, were used in two independent experiments. In the first, apples were non-destructively monitored for five months during cold storage. After that time, 34% of ‘Pinova’ and 21% of ‘Topaz’ apples displayed visible surface lesions. The increase of biospeckle activity was observed during the development of fungal disease. In the second experiment various storage conditions were used and apples were tested during their shelf life by non-destructive and destructive methods. This study showed that biospeckle activity decreased during shelf life, irrespective of storage conditions.

  4. Is selective attention the basis for selective imitation in infants? An eye-tracking study of deferred imitation with 12-month-olds.

    Science.gov (United States)

    Kolling, Thorsten; Oturai, Gabriella; Knopf, Monika

    2014-08-01

    Infants and children do not blindly copy every action they observe during imitation tasks. Research demonstrated that infants are efficient selective imitators. The impact of selective perceptual processes (selective attention) for selective deferred imitation, however, is still poorly described. The current study, therefore, analyzed 12-month-old infants' looking behavior during demonstration of two types of target actions: arbitrary versus functional actions. A fully automated remote eye tracker was used to assess infants' looking behavior during action demonstration. After a 30-min delay, infants' deferred imitation performance was assessed. Next to replicating a memory effect, results demonstrate that infants do imitate significantly more functional actions than arbitrary actions (functionality effect). Eye-tracking data show that whereas infants do not fixate significantly longer on functional actions than on arbitrary actions, amount of fixations and amount of saccades differ between functional and arbitrary actions, indicating different encoding mechanisms. In addition, item-level findings differ from overall findings, indicating that perceptual and conceptual item features influence looking behavior. Looking behavior on both the overall and item levels, however, does not relate to deferred imitation performance. Taken together, the findings demonstrate that, on the one hand, selective imitation is not explainable merely by selective attention processes. On the other hand, notwithstanding this reasoning, attention processes on the item level are important for encoding processes during target action demonstration. Limitations and future studies are discussed.

  5. Children's Comprehension of Sentences with Focus Particles and the Role of Cognitive Control: An Eye Tracking Study with German-Learning 4-Year-Olds.

    Science.gov (United States)

    Höhle, Barbara; Fritzsche, Tom; Müller, Anja

    2016-01-01

    Children's interpretations of sentences containing focus particles do not seem adult-like until school age. This study investigates how German 4-year-old children comprehend sentences with the focus particle 'nur' (only) by using different tasks and controlling for the impact of general cognitive abilities on performance measures. Two sentence types with 'only' in either pre-subject or pre-object position were presented. Eye gaze data and verbal responses were collected via the visual world paradigm combined with a sentence-picture verification task. While the eye tracking data revealed an adult-like pattern of focus particle processing, the sentence-picture verification replicated previous findings of poor comprehension, especially for 'only' in pre-subject position. A second study focused on the impact of general cognitive abilities on the outcomes of the verification task. Working memory was related to children's performance in both sentence types whereas inhibitory control was selectively related to the number of errors for sentences with 'only' in pre-subject position. These results suggest that children at the age of 4 years have the linguistic competence to correctly interpret sentences with focus particles, which--depending on specific task demands--may be masked by immature general cognitive abilities.

  6. Advocacy for eye care

    Directory of Open Access Journals (Sweden)

    Thulasiraj D Ravilla

    2012-01-01

    Full Text Available The effectiveness of eye care service delivery is often dependant on how the different stakeholders are aligned. These stakeholders range from the ministries of health who have the capacity to grant government subsidies for eye care, down to the primary healthcare workers who can be enrolled to screen for basic eye diseases. Advocacy is a tool that can help service providers draw the attention of key stakeholders to a particular area of concern. By enlisting the support, endorsement and participation of a wider circle of players, advocacy can help to improve the penetration and effectiveness of the services provided. There are several factors in the external environmental that influence the eye care services - such as the availability of trained manpower, supply of eye care consumables, government rules and regulations. There are several instances where successful advocacy has helped to create an enabling environment for eye care service delivery. Providing eye care services in developing countries requires the support - either for direct patient care or for support services such as producing trained manpower or for research and dissemination. Such support, in the form of financial or other resources, can be garnered through advocacy.

  7. A longitudinal study assessing lens thickness changes in the eye of the growing beagle using ultrasound scanning: relevance to age of dogs in regulatory toxicology studies.

    Science.gov (United States)

    Maynard, Juliana; Sykes, Angela; Powell, Helen; Healing, Guy; Scott, Marietta; Holmes, Andrew; Ricketts, Sally-Ann; Stewart, Jane; Davis, Stewart

    2014-12-01

    The lens is formed in utero with new secondary lens fibres added as outer layers throughout life in a growth pattern characteristic of the species. This study examined the time course of beagle lens growth to better understand the optimal starting age of dogs for safety studies to support adult versus paediatric indications, and to assess the feasibility of non-invasively monitoring lens growth with high frequency ultrasound. Ultrasound scanning was performed in six female beagle dogs using the Vevo770. All dogs were imaged in B-mode using local anaesthetic but without sedation. Imaging was carried out every 2 weeks from 8 to 22 weeks of age and then monthly until 62 weeks of age. The dogs tolerated the procedure well. The lens was visible in all dogs and measuring the lens thickness with high frequency ultrasound demonstrated good analytical reproducibility [Root Mean Square (RMS) = 3.13%]. No differences between the left and right eye existed and lens thickness correlated with body weight. The highest weekly growth rate was before 12 weeks of age. A statistically significant difference between monthly thickness was detected until 42 weeks of age at which point growth reached a plateau. During the experiment, lenses grew by 29.7% reaching an average thickness of 6.4 mm ± 0.03. By 10 months of age (the typical age used for routine toxicological evaluation), beagles have reached a plateau in lens growth that is analogous to human adults. Where lens is a target organ of concern it is suggested that beagles under 6 months old may be a better model for determining paediatric safety.

  8. Structure and optics of the eyes of the box jellyfish Chiropsella bronzie

    DEFF Research Database (Denmark)

    O’Connor, Megan; Garm, Anders Lydik; Nilsson, Dan-E.

    2009-01-01

    Cubomedusae have a total of 24 eyes of four morphologically different types. Two of these eye types are camera-type eyes (upper and lower lens-eye), while the other two eye types are simpler pigment pit eyes (pit and slit eye). Here, we give a description of the visual system of the box jellyfish...... species Chiropsella bronzie and the optics of the lens eyes in this species. One aim of this study is to distinguish between general cubozoan features and species-specific features in the layout and optics of the eyes. We find that both types of lens eyes are more severely under-focused in C. bronzie than...... those in the previously investigated species Tripedalia cystophora. In the lower lens-eye of C. bronzie, blur circles subtend 20 and 52° for closed and open pupil, respectively, effectively removing all but the coarsest structures of the image. Histology reveals that the retina of the lower lens-eye...

  9. Personal identification by eyes.

    Science.gov (United States)

    Marinović, Dunja; Njirić, Sanja; Coklo, Miran; Muzić, Vedrana

    2011-09-01

    Identification of persons through the eyes is in the field of biometrical science. Many security systems are based on biometric methods of personal identification, to determine whether a person is presenting itself truly. The human eye contains an extremely large number of individual characteristics that make it particularly suitable for the process of identifying a person. Today, the eye is considered to be one of the most reliable body parts for human identification. Systems using iris recognition are among the most secure biometric systems.

  10. Outcomes of Cataract Surgery in Vitrectomized Eyes

    Directory of Open Access Journals (Sweden)

    Nilüfer Koçak

    2013-01-01

    Full Text Available Pur po se: To evaluate the intraoperative complications and postoperative visual outcomes of phacoemulsification surgery for the secondary cataract in vitrectomized eyes. Ma te ri al and Met hod: We retrospectively evaluated 51 previously vitrectomized eyes of 51 patients who had undergone phacoemulsification and intraocular lens (PHACO+IOL implantation surgery. PHACO+IOL surgery was performed in our clinic between October 2008 and May 2011. Intraoperative complications and postoperative best-corrected visual acuity (BCVA outcomes were analyzed. Re sults: In this study, 31 out of 51 eyes had posterior subcapsular cataract. Cataract surgery was performed after a mean of 21.39±26.4 (6- 120, median 10.75 months following PPV. Mean preoperative and postoperative BCVA was measured to be 1.52±0.88 logMAR and 0.74±0.73 logMAR, respectively. In 25 eyes which had been filled with silicon oil, mean BCVA was 1.95±0.91 logMAR preoperatively and 1.15±0.84 logMAR postoperatively. In 18 (35.3% eyes which had been filled with sulfur hexafluoride tamponade, mean BCVA was 1.17±0.47 logMAR preoperatively and 0.38±3.6 logMAR postoperatively. Peroperative zonular dialysis with instable deep anterior chamber occurred in two eyes, and posterior capsular tear occurred in one eye. Four eyes had Nd:YAG capsulotomy due to the posterior capsular opacity during the follow-up period. Dis cus si on: Despite the well-known difficulties encountered in vitrectomized eyes such as zonular weakness, increased mobility of the lens-iris diaphragm, posterior capsular instability and posterior capsular plaques, phacoemulsification in vitrectomized eyes proved to be a safe surgery, and increase in visual acuity can be achieved. (Turk J Ophthalmol 2013; 43: 23-6

  11. Methods of statistical analysis, dimensioning and determination of production of electric power for description of the scheme applied to wind in Botucatu/ SP region, Brazil; Metodos de analise estatistica, dimensionamento e determinacao da energia eletrica produtivel para descricao do regime eolico aplicados na regiao de Botocatu-SP

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel Filho, Luis Roberto Almeida [Universidade Estadual Paulista Julio de Mesquita Filho (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas], email: gabrielfilho@tupa.unesp.br; Cremasco, Camila P. [Faculdade de Tecnologia (FATEC), Presidente Prudente, SP (Brazil); Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Dept. de Bioestatistica; Verri, Juliano A. [Universidade Estadual Paulista Julio de Mesquita Filho (FCT/UNESP), Presidente Prudente, SP (Brazil). Dept. de Matematica, Estatistica e Computacao; Viais Neto, Daniel dos S. [Faculdade de Tecnologia (FATEC), Presidente Prudente, SP (Brazil); Universidade Estadual Paulista Julio de Mesquita Filho (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas; Seraphim, Odivaldo J. [Universidade Estadual Paulista Julio de Mesquita Filho (FCA/UNESP), Botucatu, SP (Brazil). Fac. de Ciencias Agronomicas. Dept. de Engenharia Rural

    2011-07-01

    The wind energy is an abundant source of renewable energy, clean and available almost everywhere. For its use, studies are needed to adequately describe its intensity for statistical methods and design for wind turbines. The objective is to structure the mathematical methods used to conduct a general description of the wind, to establish a description of the wind regime using the parameters described using the Weibull function and the analytical model of power from a wind turbine, as well as applications of these methods show. This work was developed at Rural Empowerment Lab of FCA/UNESP in Botucatu-SP. For the application of methods were utilized measurements of wind speed and direction, between 2004 and 2005, obtained by anemometer RM Young Wind Monitor-Campbell. As a result, they estimated the wind behavior and distribution of wind in the region, with 78 kWh of energy production, relatively low potential to supply a small house. Moreover, this energy could possibly be applied in ambient illumination, power supply for electric fences and irrigation of vegetables. (author)

  12. Soil cover and determination of conflicts in the drainage network of the Lageado and Edgardia farms in Botucatu – SP, obtained from aerial photography Cobertura do solo e determinação de conflitos na rede de drenagem das fazendas Lageado e Edgardia, Botucatu – SP, obtidas de fotografias aéreas

    Directory of Open Access Journals (Sweden)

    Zacarias Xavier de Barros

    2011-10-01

    Full Text Available O presente estudo teve como objetivo discriminar, mapear, quantificar as áreas de ocupação do solo e também verificar possíveis áreas de conflito de uso do solo em Área de Preservação Permanente - APP ocorrentes nas Fazendas Lageado e Edgardia – Município de Botucatu (SP. Foram utilizadas fotografias aéreas coloridas do ano de 2005, tendo como ferramenta de avaliação o Sistema de Informação Geográfica - IDRISI Andes 15.0. A área de preservação permanente (140,91 ha está sendo ocupada por pastagens, áreas agrícolas e outros usos (24,94 h% e o restante por matas ciliares e várzeas com ocupação fragmentada. As Fazendas Lageado e Edgardia, no ano de 2005, eram ocupadas de forma predominante por matas ciliares, mostrando sua recuperação com relação ao ano de 1962; seguidas de culturas agrícolas, outras ocupações, pastagens e várzeas, respectivamente. As fotografias aéreas associadas ao SIG-Idrisi mostraram ser ferramentas eficientes no mapeamento da área e monitoramento de impactos ambientais.

  13. Study on the Protective Effect of a New Manganese Superoxide Dismutase on the Microvilli of Rabbit Eyes Exposed to UV Radiation

    Directory of Open Access Journals (Sweden)

    Lucia Grumetto

    2015-01-01

    Full Text Available We present a study on the protective effects against UV radiation of a gel formulation containing a new recombinant form of manganese superoxide dismutase on the conjunctiva and corneal epithelia of rabbit eyes. The integrity of the microvilli of both ocular tissues has been considered as an indicator of the health of the tissues. Samples, collected by impression cytology technique, were added of 80 µL of a gel formulation containing superoxide dismutase (2.0 µg/mL and irradiated with UV rays for 30 minutes and were evaluated with scanning electron microscopy. Wilcoxon test was used to verify the possible occurrence of statistically significant differences between damage for treated and nontreated tissues. Application of gel produces a significant reduction of damage by UV irradiation of ocular epithelia; both epithelia present a significant reduction of damaged microvilli number if treated with the superoxide dismutase gel formulation: the p values (differences between damage found for treated and nontreated both ocular tissues for conjunctiva and cornea samples were p≪0.01 and p≪0.0001, respectively, at confidence level of 95%. The administration of this gel formulation before UV exposure plays a considerable protective role in ocular tissues of rabbit eye with a significant reduction of the damage.

  14. What Is Eye Cancer?

    Science.gov (United States)

    ... melanomas. Melanomas develop from pigment-making cells called melanocytes . When melanoma develops in the eye, it is ... cells make the same kind of pigment as melanocytes in the skin, so it’s not surprising that ...

  15. Eye Cosmetic Safety

    Science.gov (United States)

    ... eye cosmetic a source of lead poisoning?" Israel Journal of Medical Science, 1992 July; 28(7):417-21. Parry C, ... Compliance Federal, State & Local Officials Consumers Health Professionals ... Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products

  16. About the Eye

    Medline Plus

    Full Text Available ... NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to ... Grants and Funding Extramural Research Division of Extramural Science Programs Division of Extramural Activities Extramural Contacts NEI ...

  17. Diabetic Eye Problems

    Science.gov (United States)

    ... damage your eyes. The most common problem is diabetic retinopathy. It is a leading cause of blindness ... You need a healthy retina to see clearly. Diabetic retinopathy damages the tiny blood vessels inside your ...

  18. Multimodal eye recognition

    Science.gov (United States)

    Zhou, Zhi; Du, Yingzi; Thomas, N. L.; Delp, Edward J., III

    2010-04-01

    Multimodal biometrics use more than one means of biometric identification to achieve higher recognition accuracy, since sometimes a unimodal biometric is not good enough used to do identification and classification. In this paper, we proposed a multimodal eye recognition system, which can obtain both iris and sclera patterns from one color eye image. Gabor filter and 1-D Log-Gabor filter algorithms have been applied as the iris recognition algorithms. In sclera recognition, we introduced automatic sclera segmentation, sclera pattern enhancement, sclera pattern template generation, and sclera pattern matching. We applied kernelbased matching score fusion to improve the performance of the eye recognition system. The experimental results show that the proposed eye recognition method can achieve better performance compared to unimodal biometric identification, and the accuracy of our proposed kernel-based matching score fusion method is higher than two classic linear matching score fusion methods: Principal Component Analysis (PCA) and Linear Discriminant Analysis (LDA).

  19. Common Eye Disorders

    Science.gov (United States)

    ... ability to focus up close, inability to read letters of the phone book, need to hold newspaper ... group of diseases that can damage the eye's optic nerve and result in vision loss and blindness. ...

  20. Eye Injuries in Construction

    Science.gov (United States)

    ... from a power tool (like a drill or wheel) , OR ! If your eye is cut or punctured : • ... CIO: CPWR, Suite 1000, 8484 Georgia Ave., Silver Spring, MD 20910. (Edward C. Sullivan is presiden