WorldWideScience

Sample records for book imprints

  1. Imprinting disorders

    DEFF Research Database (Denmark)

    Eggermann, Thomas; Perez de Nanclares, Guiomar; Maher, Eamonn R;

    2015-01-01

    Congenital imprinting disorders (IDs) are characterised by molecular changes affecting imprinted chromosomal regions and genes, i.e. genes that are expressed in a parent-of-origin specific manner. Recent years have seen a great expansion in the range of alterations in regulation, dosage or DNA...... impacts upon growth, development and metabolism. Thus, detailed and systematic analysis of IDs can not only identify unifying principles of molecular epigenetics in health and disease, but also support personalisation of diagnosis and management for individual patients and families....

  2. Imprinting in plants

    Institute of Scientific and Technical Information of China (English)

    GUTIERREZ-MARCOS Jose

    2009-01-01

    Genomic imprinting leads to the differential expression of parental alleles after fertilization. Imprinting appears to have evolved independently in mammals and flowering plants to regulate the development of nutrient-transfer placental tissues. In addition, the regulation of imprinting in both mammals and flowering plants involves changes in DNA methylation and histone methylation, thus suggesting that the epigenetic signals that regulate imprinting have been co-opted in these distantly related species.

  3. Congenital imprinting disorders

    DEFF Research Database (Denmark)

    Eggermann, Thomas; Netchine, Irène; Temple, I Karen;

    2015-01-01

    Imprinting disorders (IDs) are a group of eight rare but probably underdiagnosed congenital diseases affecting growth, development and metabolism. They are caused by similar molecular changes affecting regulation, dosage or the genomic sequence of imprinted genes. Each ID is characterised...... their common underlying (epi)genetic aetiologies, and their basic pathogenesis and long-term clinical consequences remain largely unknown. Efforts to elucidate the aetiology of IDs are currently fragmented across Europe, and standardisation of diagnostic and clinical management is lacking. The new consortium...... EUCID.net (European network of congenital imprinting disorders) now aims to promote better clinical care and scientific investigation of imprinting disorders by establishing a concerted multidisciplinary alliance of clinicians, researchers, patients and families. By encompassing all IDs and establishing...

  4. In Celebration: The National Union Catalog, Pre-1956 Imprints.

    Science.gov (United States)

    Cole, John Y., Ed.

    This document contains the principal papers from a 1981 symposium held to celebrate the completion of the 754-volume National Union Catalog, Pre-1956 Imprints. Papers by both those who use the National Union Catalog (NUC) and those who developed it are included. A brief preface describes the mission of the Center for the Book and the purpose of…

  5. Book Review: Book review

    Science.gov (United States)

    Manohar, C. S.

    2015-02-01

    The subject of the theory of vibrations has carried an aesthetic appeal to generations of engineering students for its richness of ideas, and for the intellectual challenges it offers. Also, the diverse range of its applications (covering civil, mechanical, automotive, and aerospace structures) has provided obvious motivations for its study. For most students, the subject provides, perhaps, the first encounter in substantial application of mathematical tools (differential equations, calculus of variations, Fourier/Laplace transforms, and matrix algebra) to engineering problems. The intimate relationship that the subject of mechanics has with mathematics strikes home probably for the first time. While teaching this subject, the instructor is spoilt for choice in selecting a text book and so are the students who wish to pursue a self-study of the subject. Many luminaries in the field have offered their own exposition of the subject: starting from the classics of Rayleigh, Timoshenko, Den Hartog, Bishop and Johnson, and the works of more recent vintage (e.g., the books by Meirovich, Clough, and Penzien, and works with computational flavour, such as, those by Bathe and Petyt), several works easily come to one's mind. Given this milieu, it requires a distinctive conviction to write a new book on this subject. And, here we have a book, written by a practitioner, which aims to deal with fundamental aspects of vibrations of engineering systems. The scepticism that this reviewer had on the need for having one more such book vanished as he browsed through the book and read selectively a few sections. The author's gift for elegant explanations is immediately noticeable even in such a preliminary reading. After a more careful reading, the reviewer has found this book to be insightful and he considers the book to be a welcome addition to the family of books on vibration engineering. The author has struck a fine balance between physical explanations, mathematical niceties

  6. Solvent Immersion Imprint Lithography

    Energy Technology Data Exchange (ETDEWEB)

    Vasdekis, Andreas E.; Wilkins, Michael J.; Grate, Jay W.; Kelly, Ryan T.; Konopka, Allan; Xantheas, Sotiris S.; Chang, M. T.

    2014-06-21

    The mechanism of polymer disolution was explored for polymer microsystem prototyping, including microfluidics and optofluidics. Polymer films are immersed in a solvent, imprinted and finally brought into contact with a non-modified surface to permanently bond. The underlying polymer-solvent interactions were experimentally and theoretically investigated, and enabled rapid polymer microsystem prototyping. During imprinting, small molecule integration in the molded surfaces was feasible, a principle applied to oxygen sensing. Polystyrene (PS) was employed for microbiological studies at extreme environmental conditions. The thermophile anaerobe Clostridium Thermocellum was grown in PS pore-scale micromodels, revealing a double mean generation lifetime than under ideal culture conditions. Microsystem prototyping through directed polymer dissolution is simple and accessible, while simultaneous patterning, bonding, and surface/volume functionalization are possible in less than one minute.

  7. Categories with envelopes and imprints

    CERN Document Server

    Akbarov, Sergei

    2011-01-01

    An envelope in a category is a construction generalizing operations of "exterior completion", like completion of a locally convex space. Dually, an imprint generalizes operations of "interior enrichment", like saturation of a locally convex space. We give abstract definition for envelopes and imprints, prove existence of these objects in the categories of stereotype spaces and of stereotype algebras, and give some examples.

  8. Molecularly imprinted polymers for mycotoxins

    Science.gov (United States)

    Molecularly imprinted polymers (MIPs) are a class of synthetic receptors capable of selective recognition of analytes. Recent developments in imprinting technology have made it possible to apply this technology in a range of applications, including mycotoxin detection. Structure-activity relations...

  9. Book Review: Book review

    Science.gov (United States)

    Clevers, Jan G. P. W.

    2016-09-01

    For many years a good introductory book for undergraduate and postgraduate students on remote sensing of the Earth's land surface, which was not starting with an emphasis on traditional photographic techniques, was missing. In 2010 the first edition of the book Fundamentals of Satellite Remote Sensing by Emilio Chuvieco and Alfredo Huete was published by CRC Press and it was filling this gap. Now the second edition by Emilio Chuvieco was published by CRC Press. This second edition is made more attractive by the use of colour and including colour illustrations instead of the black-and-white ones in the first edition.

  10. Children's Books. Book Reviews.

    Science.gov (United States)

    Moulton, Kate

    1994-01-01

    Reviews 10 children's books, published or reissued 1988-93, about daily life, traditional culture, and schooling among Taos Pueblo, Zuni Pueblo, Navajo, Inuit, Guatemalan, and other Native peoples, as well as tales from Native American oral tradition, the life of a buffalo, and Cherokee and Athapascan historical fiction. Includes grade range and…

  11. Book Review: Book review

    Science.gov (United States)

    Fonte, Cidália C.

    2016-02-01

    The use of geospatial data for a wide variety of applications has increased continuously over the last decades and a great variety of packages of open source GIS software are now available, with diverse characteristics. R was created as free software mainly for statistical computation and graphics, but offers now a large diversity of packages to process and visualize spatial data. Many books dedicated to R are available (e.g., Zuur et al., 2009; Chambers, 2008), but not many about spatial analysis in R (Bivand et al., 2008). The book under analysis is aimed for beginners both in R and in spatial analysis, and therefore can be used as a starting point for students and professionals which may want to enter the area of spatial analysis with R.

  12. Book Review: Book review

    Science.gov (United States)

    van der Linden, Sebastian

    2016-05-01

    Compiling a good book on urban remote sensing is probably as hard as the research in this disciplinary field itself. Urban areas comprise various environments and show high heterogeneity in many respects, they are highly dynamic in time and space and at the same time of greatest influence on connected and even tele-connected regions due to their great economic importance. Urban remote sensing is therefore of great importance, yet as manifold as its study area: mapping urban areas (or sub-categories thereof) plays an important (and challenging) role in land use and land cover (change) monitoring; the analysis of urban green and forests is by itself a specialization of ecological remote sensing; urban climatology asks for spatially and temporally highly resolved remote sensing products; the detection of artificial objects is not only a common and important remote sensing application but also a typical benchmark for image analysis techniques, etc. Urban analyses are performed with all available spaceborne sensor types and at the same time they are one of the most relevant fields for airborne remote sensing. Several books on urban remote sensing have been published during the past 10 years, each taking a different perspective. The book Global Urban Monitoring and Assessment through Earth Observation is motivated by the objectives of the Global Urban Observation and Information Task (SB-04) in the GEOSS (Global Earth Observation System of Systems) 2012-2015 workplan (compare Chapter 2) and wants to highlight the global aspects of state-of-the-art urban remote sensing.

  13. Step & flash imprint lithography

    Directory of Open Access Journals (Sweden)

    Douglas J. Resnick

    2005-02-01

    Full Text Available The escalating cost of next generation lithography (NGL is driven in part by the need for complex sources and optics. The cost for a single NGL tool could soon exceed $50 million, a prohibitive amount for many companies. As a result, several research groups are looking at alternative, low-cost methods for printing sub-100 nm features. Many of these methods are limited in their ability to do precise overlay. In 1999, Willson and Sreenivasan developed step and flash imprint lithography (S-FIL™. The use of a quartz template opens up the potential for optical alignment of the wafer and template. This paper reviews several key aspects of the S-FIL process, including template, tool, ultraviolet (UV-curable monomer, and pattern transfer. Two applications are also presented: contact holes and surface acoustic wave (SAW filters.

  14. Book Review: Book review

    Science.gov (United States)

    da Costa, Newton C. A.; Krause, Décio

    This book contains a representative selection of Erhard Scheibe's writings on the philosophy of physics. It encompasses eight sections, with 38 papers, distributed as follows: (I) Between Rationalism and Empiricism (five papers from 1969 to 1994); (II) The Philosophy of the Physicists (five papers from 1988 to 1995); (III) Reconstruction (four papers, from 1979 to 1988); (IV) Laws of Nature (five papers, from 1989 to 1998); (V) Reduction (five papers from 1973 to 1995); (VI) Foundations of Quantum Mechanics (six papers from 1985 to 1993); (VII) Spacetime, Invariance, Covariance (four papers from 1982 to 1994), and (VIII) Mathematics and Physics (four papers from 1977 to 1997).

  15. Book Act

    OpenAIRE

    Kivland, Sharon

    2014-01-01

    Book Act was a new project by AMBruno, initiated by Sophie Loss, in which artist book-makers performed and embodied the concept or essence of their books through the medium of film or performance. The exhibition at The Tetley, Leeds, comprised the originating books and corresponding video work, with live performances on Sunday 9 March 2014. Book Act took place during the 17th International Contemporary Artists' Book Fair (7th to 9th March) and the exhibition continued until 26th March 2014.

  16. Book Review: Book review

    Science.gov (United States)

    Kragh, Helge

    While "hydrostatics" has been known since antiquity, the word "hydrodynamics" was only coined by Daniel Bernoulli in 1738. From about that time onward the mechanics of fluids became an important area of physics which attracted the interest of some of the greatest mathematical physicists, including Euler, d'Alembert, Lagrange and Cauchy. Yet, in spite of its undeniable importance in the history of science, hydrodynamics has been largely ignored by modern historians. Fortunately this situation has now changed with the publication of Olivier Darrigol's book, which offers a modern and thorough treatment of the subject from its beginning about 1740 to the 1920s. It is to be hoped that the book will stimulate further interest in the history of hydrodynamics and related areas such as the history of elasticity and aerodynamics, and continuum mechanics in general. Darrigol, who may be best known for his works in the history of quantum and relativity theories, published in 2000 a comprehensive survey of the development of electrodynamics from Ampère to Einstein, a much needed replacement of Edmund Whittaker's classical history of ether and electricity. His present work gives a concise yet wide-ranging synthetic account of the development of hydrodynamics, an area of physics with some historical connections to field electrodynamics.

  17. Imprinting: a gamete's point of view.

    Science.gov (United States)

    Barlow, D P

    1994-06-01

    The recent isolation of imprinted mammalian genes has at last allowed the analysis of the molecular controls that regulate monoparental gene expression. Remarkably, many expectations as to how the imprinting mechanism works have been confounded by these studies. As a result, the time now seems right to reconsider our current understanding of the nature of imprinting, and how best it can be defined. Here, I discuss the past and present understanding of imprinting in the light of results obtained from studies of endogenous imprinted genes, and finally propose that the current multiplicity of imprinting terms and definitions be replaced by a single term and definition. PMID:7864936

  18. Book Review: Book review

    Science.gov (United States)

    Roberts, John T.

    Mauro Dorato's new book is subtitled "An Introduction to the History and Philosophy of Laws of Nature". This is a bit misleading: a reader previously unacquainted with any of the literature on the topic of laws of nature and related problems in the philosophy of science will find much of the book prohibitively challenging. But the book does aim for the kind of breadth and generality that one would expect from an introduction to the subject, and it serves well as a compact overview of the issues, views, arguments, and counter-arguments that have shaped the contemporary philosophical debate on laws of nature. Almost no important facet of the debate goes untouched. There are chapters or sections on: recent scholarship on the history of the notion of a law and its role in the study of nature; the characteristics of the things called "laws" in a wide range of sciences; the relations among laws, algorithmic compressibility of information, and the theory of measurement; the puzzling question of why so many laws of nature should be mathematical in form; regularity theories of laws; the universals approach to laws; the necessitarian approach to laws; skeptical eliminativism about laws; non-reductive realism about laws; the question of the supervenience of laws on non-nomic facts; the relations of laws to counterfactuals, causality, dispositions, explanation, chance, symmetry, and necessity; ceteris paribus clauses; the evolutionary contingency thesis and the question of biological laws; Wilhelm Dilthey and the alleged distinction between "nomothetic" sciences and "historical" ones; the question of psychophysical laws and the relation between this question and the problems of mental causation and free will; even the connection between the issue of psychophysical laws and Gibson's ecological theory of perception. This is an impressive range of topics, especially considering that they are all treated in only 174 pages. One result is that not all of them are treated with as

  19. Imprint lithography advances in LED manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Hershey, Robert; Doyle, Gary; Jones, Chris; LaBrake, Dwayne; Miller, Mike [Molecular Imprints Inc., 1807 West Braker Lane, Building C-11, Austin, TX 78758 (United States)

    2007-07-01

    Imprint lithography is a promising cost effect alternative to e-beam and optical lithography for producing photonic crystals and other nano-scale light extraction and beam directing elements for LEDs; however, there are several challenges that must be overcome before imprint lithography can be applied to typical LED substrates. This paper reviews progress made at Molecular Imprints Inc. (MII) in imprinting representative 3{sup ''} GaN on Sapphire substrates including methods for dealing with substrate non-flatness, multi-die imprint, and imprinting on warped and bowed substrates. The results of imprinting over typical GaN on Sapphire topography and common defects such as fall-on particles and EPI defects is presented along with results on GaN wafers optimized for imprint lithography. Whole wafer thin template replication techniques are also discussed. (copyright 2007 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  20. Direct Imprinting of Liquid Silicon.

    Science.gov (United States)

    Masuda, Takashi; Takagishi, Hideyuki; Yamazaki, Ken; Shimoda, Tatsuya

    2016-04-20

    A polymeric precursor solution for semiconducting silicon called "liquid silicon" was synthesized and directly imprinted to form well-defined and fine amorphous silicon patterns. The spin-coated film was cured and imprinted followed by annealing at 380 °C to complete the polymer-to-silicon conversion. A pattern with dimensions of several hundreds of nanometers or less was obtained on a substrate. We demonstrated that the curing step before imprinting is particularly important in the imprinting process. A curing temperature of 140-180 °C was found to be optimal in terms of the film's deformability and molding properties. Fourier transform infrared spectroscopy and thermal analysis clarified that the cross-linking of the polymer due to the 1,2-hydrogen shift reaction was induced exponentially with the release of a large amount of SiH4/H2 gases at temperatures between 140 and 220 °C, leading to the solidification of the film. Consequently, the film completely lost its deformability at higher temperatures. Despite a volume shrinkage as large as 53-56% during the polymer-to-silicon conversion, well-defined angular patterns were preserved. Fine silicon patterns were formed via the direct imprinting of liquid silicon with high resolution and high throughput, demonstrating the usefulness of this technique for the future manufacturing of silicon electronics. PMID:27028558

  1. Imprinting and recalling cortical ensembles.

    Science.gov (United States)

    Carrillo-Reid, Luis; Yang, Weijian; Bando, Yuki; Peterka, Darcy S; Yuste, Rafael

    2016-08-12

    Neuronal ensembles are coactive groups of neurons that may represent building blocks of cortical circuits. These ensembles could be formed by Hebbian plasticity, whereby synapses between coactive neurons are strengthened. Here we report that repetitive activation with two-photon optogenetics of neuronal populations from ensembles in the visual cortex of awake mice builds neuronal ensembles that recur spontaneously after being imprinted and do not disrupt preexisting ones. Moreover, imprinted ensembles can be recalled by single- cell stimulation and remain coactive on consecutive days. Our results demonstrate the persistent reconfiguration of cortical circuits by two-photon optogenetics into neuronal ensembles that can perform pattern completion. PMID:27516599

  2. Genomic imprinting and assisted reproduction

    Directory of Open Access Journals (Sweden)

    Chaillet J Richard

    2004-10-01

    Full Text Available Abstract Imprinted genes exhibit a parent-of-origin specific pattern of expression. Such genes have been shown to be targets of molecular defects in particular genetic syndromes such as Beckwith-Wiedemann and Angelman syndromes. Recent reports have raised concern about the possibility that assisted reproduction techniques, such as in vitro fertilization or intracytoplasmic sperm injection, might cause genomic imprinting disorders. The number of reported cases of those disorders is still too small to draw firm conclusions and the safety of these widely used assisted reproduction techniques needs to be further evaluated.

  3. Imprinted photonic crystal chemical sensors

    NARCIS (Netherlands)

    Boersma, A.; Burghoorn, M.M.A.; Saalmink, M.

    2011-01-01

    In this paper we present the use of Photonic Crystals as chemical sensors. These 2D nanostructured sensors were prepared by nano-imprint lithography during which a nanostructure is transferred from a nickel template into a responsive polymer, that is be specifically tuned to interact with the chemic

  4. Book Reviews.

    Science.gov (United States)

    Powicke, J. C.; And Others

    1986-01-01

    Reviews of 10 recent books and one new journal ("Catalyst: A Journal of Policy Debate") are provided. Topics of the books reviewed include: economics in modern Britain, world economics, the mixed economy, Milton Friedman's thought, British industry, economic issues, and London as a financial center. (JDH)

  5. Book Review

    Directory of Open Access Journals (Sweden)

    Adrian Brown

    2011-01-01

    Full Text Available Phillip M. Morse and Herman Feshbach, Professors of Physics at the MIT, published their biblical-sized textbook ‘Methods of Theoretical Physics’ with McGraw-Hill in May 1953. At 1978 pages and published in two books, it is an intimidating twin tome that should still be atop the reading lists or the bookshelves of every mathematical physicist. What material is covered in this book? In the most concise of terms, this book is devoted to the study of differential equations and associated boundary conditions that describe physical fields. The thirteen chapters address what circumstances warrant the use of which differential equations, and most often addresses the question of coordinate system transformations, for example, how do Green's functions for Laplace's Equation transform under different coordinate systems? Under what circumstances the solutions can be expected to be separable? Many examples are covered to illustrate these points. Why is this book relevant to Software Programmers? This book is part of the background that any scientific programmer is likely to need in dealing with physical fields. This book was written before personal computers became ubiquitous, however it is still an outstanding effort to tie the methods of solving differential equations governing fields together in one book. The book never received a second edition, however, it was reprinted to an outstanding standard by Feshbach Publishing since 2004, run by the children of Herman Feshbach. Their website is feshbachpublishing.com. The majority of this review is a mini-commentary of the book showing what is covered in a very terse fashion, which may be useful as a summary even for those who have already read the full text. I then give a brief analysis of the approach to mathematical physics taken by the book. Finally, I will discuss who will benefit from reading this magnificent treatise, nearly 60 years after it was first published.

  6. Book Factory: Making Homemade Books

    Science.gov (United States)

    Church, Ellen Booth

    2005-01-01

    The process of creating handmade books with children is a great way to experience communication through art and words. One of the important literacy skills children need to learn is "concepts of print." These include the basic understanding of what a book is, the ability to recognize the front and back covers, and the capacity to turn the pages…

  7. Indexing books

    CERN Document Server

    Mulvany, Nancy C

    2009-01-01

    Since 1994, Nancy Mulvany's Indexing Books has been the gold standard for thousands of professional indexers, editors, and authors. This long-awaited second edition, expanded and completely updated, will be equally revered.Like its predecessor, this edition of Indexing Books offers comprehensive, reliable treatment of indexing principles and practices relevant to authors and indexers alike. In addition to practical advice, the book presents a big-picture perspective on the nature and purpose of indexes and their role in published works. New to this edition are discus

  8. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    4th Dalai Lama Yundain GyamcoAuthored by 5th Dalai Lama and translated by Chen Qingying and Ma Lianlong, the book tells the life of the 4th Dalai Lama who was the only non-Tibetan among the various generations of the Dalai Lama.As he was the first reincarnated Mongolian Living Buddha of the Gelug Sect, he held an important position in the history of the Gelug Sect. His period was a period filled with social changes, and little historical materials are found to cover his period. Publication of the book, published by the Tapei All Buddhist Cultural Undertakings Co. Ltd., is obviously a must-read book.

  9. Book Review:

    Science.gov (United States)

    Gregory, Ruth

    2007-06-01

    The study of braneworlds has been an area of intense activity over the past decade, with thousands of papers being written, and many important technical advances being made. This book focuses on a particular aspect of braneworlds, namely perturbative gravity in one specific model: the Randall-Sundrum model. The book starts with an overview of the Randall-Sundrum model, discussing anti-de Sitter (AdS) space and the Israel equations in some detail. It then moves on to discuss cosmological branes, focusing on branes with constant curvature. The book then turns to brane gravity, i.e. what do we, as brane observers, perceive the gravitational interaction to be on the brane as derived from the actual five-dimensional gravitational physics? After a derivation of the general brane equations from the Israel equations, the remainder of the book deals with perturbative gravity. This part of the book is extremely detailed, with calculations given explicitly. Overall, the book is quite pedagogical in style, with the aim being to explain in detail the topics it chooses to cover. While it is not unusual to have books written on current and extremely popular research areas, it is unusual to have calculations written so explicitly. This is both a strength and a weakness of this book. It is a strength because the calculations are presented in a detail that students learning the topic will definitely appreciate; however, the narrow focus of the book also means that it lacks perspective and fails to present the broader context. In choosing to focus on one particular aspect of Randall-Sundrum branes, the book has not managed to communicate why a large number of theorists have worked so intensively on this model. In its early stages, the explicit detail of the Randall-Sundrum model would be extremely useful for a student starting out in this research area. In addition, the calculational detail later in the computation of the graviton propagator on the brane would also be welcome not

  10. Book Reviews

    OpenAIRE

    Mattijs Vandezande

    2010-01-01

    BOOK REVIEW Migrants and Urban Change: Newcomers to Antwerp, 1760-1860, Perspectives in Economic and Social History by Anne Winter REVIEWED BY MATTIJS VANDEZANDE London, Pickering & Chatto, 2009, ISBN 978-18-5196-646-2, 318 pp.

  11. Orange Book

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Approved Drug Products with Therapeutic Equivalence (Orange Book or OB) is a list of drugs approved under Section 505 of the Federal Food, Drug and Cosmetic Act...

  12. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    CHINA'S SPACE TRAVEL On October 16, 2003 China successfully launched its first manned space flight. This book records the course of China's manned space undertaking, and development of its manned space flight. It includes 200 color plates relating to the Seven Systems of China's Manned Space Mission; Development of the Shenzhou Spacecraft; City of Dreams in the Gobi Desert; Yang Liwei-China's First Astronaut; and Chronology of the First Manned Space Flight. The book is appended with Memorabilia of China'...

  13. Molecularly imprinted polymers as synthetic mimics of bioreceptors. 1. General principles of molecular imprinting

    Directory of Open Access Journals (Sweden)

    Sergeyeva T. A.

    2009-08-01

    Full Text Available The review is devoted to analysis of the publications in the area of synthesis of artificial mimics of biological receptors using the method of molecular imprinting. General principles of molecular imprinting as well as main types of polymers being used in molecular imprinting are described. The special attention is paid to the polymers-biomimics synthesized using the method of non-covalent molecular imprinting.

  14. Molecularly imprinted polymers: synthesis and characterisation.

    Science.gov (United States)

    Cormack, Peter A G; Elorza, Amaia Zurutuza

    2004-05-01

    This short review aims to present, in clear English, a summary of the principal synthetic considerations pertaining to good practice in the polymerisation aspects of molecular imprinting, and is primarily aimed at researchers familiar with molecular imprinting methods but with little or no prior experience in polymer synthesis. It is our hope that this will facilitate researchers to plan their own syntheses of molecular imprints in a more logical and structured fashion, and to begin to appreciate the limitations of the present synthetic approaches in this molecularly complex area, as well as the scope for rationally designing improved imprinted materials in the future.

  15. Electronic book – paperless book

    Directory of Open Access Journals (Sweden)

    Mateja Ločniškar-Fidler

    2003-01-01

    Full Text Available The article presents the electronic book, which is accessible on the Internet, with particularities and drawbacks that the present and future users and librarians may encounter.It also presents devices (such as scanners and hand-helds and software required for reading and designing electronic books, as well as the details we should pay attention to when buying and using the above mentioned devices. Some of the most significant web pages dedicated to the selling and promoting of electronic books are also presented. The protection of authors’ works, distributed via the Internet and digital media, is gaining importance. In September 1999, Slovenia also joined the international agreement on the protection of copyrights. It is expected that electronic books will gradually become part of the collection of all types of libraries. Therefore, libraries will need appropriate technical equipment as well as trained personnel for the usage of this new medium.

  16. Book Review

    Science.gov (United States)

    Bokulich, Alisa

    In recent years, there has been a growing resurgence of interest in the philosophical views of the founders of quantum mechanics. Kristian Camilleri's book on Werner Heisenberg's philosophy of quantum mechanics is a welcome addition to this literature. It takes Heisenberg seriously as a philosopher of science, traces the various philosophical influences on his view, and carefully distinguishes his interpretation of quantum mechanics from that of his contemporaries. It is a fine example of the new insights that can emerge when one takes an integrated approach to the history and philosophy of science. After summarizing some of the main themes of the book, I will turn to two moderate criticisms of the book-one stylistic, and the other, regarding its content.

  17. Book Review

    Science.gov (United States)

    Mishchenko, Michael I.

    2016-08-01

    The main purpose of this exemplary book is to provide a systematic exposition of the entire field of optical tweezers and their applications. The book is divided into three (approximately equal) parts summarizing the electromagnetic theory of optical tweezers (Part I), the practice of designing and building optical tweezers (Part II), and extensive applications of optical tweezers in various branches of science (Part III). The exposition is highly methodical and addresses the needs of anyone dealing with optical tweezers, be it a theoretician, an engineer/experimentalist, a routine practitioner, or an interested scientist.

  18. Book Review

    Science.gov (United States)

    Clevers, J. G. P. W.

    2015-02-01

    About thirty years after the previous advanced textbook on Microwave Remote Sensing by Ulaby, Moore and Fung has been published as three separate volumes, now an up-to-date new textbook has been published. The 1000-page book covers theoretical models, system design and operation, and geoscientific applications of active and passive microwave remote sensing systems. It is designed as a textbook at the postgraduate level, as well as a reference for the practicing professional. The book is caught by a thorough introduction into the physics and mathematics of electrical engineering applied to microwave radiation. Here on overview of its chapters with a short description of its focus will be given.

  19. Book Review

    DEFF Research Database (Denmark)

    Pace, Michelle

    2016-01-01

    At the turn of the millennium, a new phenomenon emerged: conservatives, who just decades before had rejected the expanding human rights culture, began to embrace human rights in order to advance their political goals. In this book, Nicola Perugini and Neve Gordon account for how human rights...... to dispossess indigenous Palestinians and military think-tanks that rationalize lethal violence by invoking human rights. The book underscores the increasing convergences between human rights NGOs, security agencies, settler organizations, and extreme right nationalists, showing how political actors...

  20. Imprinting disorders after assisted reproductive technologies

    DEFF Research Database (Denmark)

    Lidegaard, Øjvind; Pinborg, Anja; Andersen, Anders Nyboe

    2006-01-01

    To assess the evidence of an increased risk of imprinting diseases in children born after use of assisted reproductive technologies.......To assess the evidence of an increased risk of imprinting diseases in children born after use of assisted reproductive technologies....

  1. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    CHINA’S SPACE TRAVEL On October 16, 2003 China successfully launched its first manned space flight. This book records the course of China’s manned space undertaking, and development of its manned space flight. It includes 200 color plates relating to the Seven Systems

  2. Book Reviews.

    Science.gov (United States)

    Lance, Larry M.; And Others

    1987-01-01

    Reviews the following Human Sexuality books: "Taking Sides: Clashing Views on Controversial Issues in Human Sexuality" (Francoeur, R.T., 1987); "Annual Editions: Human Sexuality" (Pocs, O., 1987); "Personal Issues in Human Sexuality" (Gordon, S. and Snyder, W., 1986); "Journey Into Sexuality: An Exploratory Voyage" (Reiss, I.L., 1986); and…

  3. Book Reviews.

    Science.gov (United States)

    Cole, Michael; And Others

    1993-01-01

    Reviews four books: (1) "On Intelligence. . .More or Less: A Bioecological Treatise on Intellectual Development" (Stephen J. Ceci); (2) "Knowing Children: Experiments in Conversation and Cognition" (Michael Siegal); (3) "Adolescents and Their Families: Paths of Ego Development" (S. T. Hauser and others); and (4) "Adolescence: An Anthropological…

  4. Book review

    NARCIS (Netherlands)

    Nauta, M.M.

    2005-01-01

    This Festschrift contains 44 lichenological contributions and is published on the occasion of Hertel’s 65th birthday. The 79 contributing authors represent 19 different countries. Lecidiaceae sensu lato are well represented in this book, which covers a vast array of lichens of different sytematic po

  5. Book Reviews.

    Science.gov (United States)

    Joyner, Christopher C.; And Others

    1986-01-01

    Scholarly reviews of nine books are presented. Topics include nuclear deterrence, urban planning in France, human rights in the Republic of China, the United States' support of Israel, U. S. military policy, an analysis of Rousseau's social contract, political influences on the U. S. presidency, the state and political theory, and the loss of…

  6. Book Reviews

    OpenAIRE

    Matthews, Alan; Goldin, Ian; Colman, David; Bickerton, Thomas W.; BEGHIN, JOHN C; Croci-Angelini, Elisabetta

    1992-01-01

    Books reviewed include: Principles of Agricultural Economics by D. Colman and T. Young; World Agriculture: Toward 2000 by Nikos Alexandratos; Food Subsidies in Developing Countries: Costs, Benefits and Policy Options; Elasticities in International Agricultural Trade by Colin A. Carter and W. H. Gardiner; Macroeconomics, Agriculture and Exchange Rates; Government and Agriculture in Western Europe, 1880-1988 by M. Tracy

  7. Book Reviews.

    Science.gov (United States)

    Agathonos-Georgopoulou, Helen; And Others

    1993-01-01

    Reviews seven books: (1) "Cross-Cultural Psychology" (Berry and others); (2) "Biological Asymmetry and Handedness" (Bock and Marsh); (3) "Interpersonal and Identity Development" (Vandenplas-Holper and Campus); (4) "Natural Theories of Mind" (Whitten); (5) "The Psychological Examination of the Child" (Blau); (6) "Knowing Children: Experiments in…

  8. Book Reviews

    OpenAIRE

    Barros, Geraldo Sant'Ana de Camargo; Lele, Uma; Haraldsson, Ingemar

    1989-01-01

    Books Reviewed: The World Coffee Market and the International Coffee Agreement by M.Th.A. Pieterse and H.J. Silvis; Agricultural Marketing Enterprises for the Developing World by J.C. Abbott; Marketing Improvement in the Developing World: What Happens and What We Have Learned; Agricultural Marketing Strategy and Pricing Policy

  9. Book reviews

    NARCIS (Netherlands)

    NN,

    2003-01-01

    This book is dedicated to the world-known specialist in marine mycology, E. B. Gareth Jones on the occasion of his 65th birthday, for his substantial contribution to marine mycology. It contains 22 contributions by a multitude of authors, grouped around the central theme of Fungi in marine environme

  10. Banning Books.

    Science.gov (United States)

    Trede, Mildred

    1991-01-01

    The "Game of Decisions" is presented to encourage students to consider the consequences of banning books and/or ideas. The game involves story writing, creating probability graphs, writing a letter protesting censorship from a chosen historical period, and examining a controversial science issue. Three thesis statements for generating group…

  11. Book review

    NARCIS (Netherlands)

    NN,

    2003-01-01

    This book is entirely dedicated to the functional role of fungi in all kind of ecosystems, and it attempts to show how the world would function if fungi were not there. It is conceived as an introduction to the subject for students in mycology and ecology. The introductory chapters deal with fundame

  12. Book reviews

    NARCIS (Netherlands)

    NN,

    2004-01-01

    Since the publication of the first edition of this book, important developments in biotechnology and mushroom production made a new, revised version necessary. As it is written for the mushroom industry, it emphasizes on nutritional, medical, and cultivating aspects of edible and medicinal fungi. A

  13. Book Reviews.

    Science.gov (United States)

    Coates, Elizabeth; And Others

    1993-01-01

    Reviews three books: (1) "Jeux Populaires Traditionnels pour les Enfants d'aujourd'hui" (Traditional Popular Games for Today's Children) (Jacqueline Theriault and Denise Garon); "Early Childhood Education" (B. Persky and L. Golubchick, editors); and "Playing to Learn: The Young Child, Teacher and the Classroom" (Weininger and Daniel). (AC)

  14. Thin book

    DEFF Research Database (Denmark)

    En lille bog om teater og organisationer, med bidrag fra 19 teoretikere og praktikere, der deltog i en "Thin Book Summit" i Danmark i 2005. Bogen bidrager med en state-of-the-art antologi om forskellige former for samarbejde imellem teater og organisationer. Bogen fokuserer både på muligheder og...

  15. BOOK REVIEWS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    This book by Professor Chen Yunü is a multi-faceted study of Buddhism during the Ming dynasty (1368-1644).The aim of the research as stated by the author is to clarify the social role of Buddhist institutions during that period and to explicate the "laicization" of Buddhism during the Ming (pp.30-31).

  16. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Study of Nuns of Tibetan Buddhism Nuns constitute a part of members of Tibetan Buddhism. Recent years have seen more girls and women apply to be nuns. Studying the why and the female body of the members of Tibetan Buddhism is therefore of practical significance. Authored by Degyi Zholma, the book provides a panoramic description of nuns, including history and status quo. To write

  17. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Selected Works on Historical Documents of Tibet (XXI);Collection of Journals on Tibetan Studies;Guidance to Traditional Architecture in Tibet;Concise History of Tibetan Music;Concise History of Tibetan Fine Arts;Series Books on Himalayas;Trekking in Tibet。

  18. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Zhang Jingwu and Tibetan Liberation The Research Office of Party History of the Committee of the Tibet Autonomous Region edited this book. In the 1950s, Zhang Jingwu received orders to Tibet. He was designated as the representative of the Central Government

  19. Electronic Books

    Science.gov (United States)

    Clyde, Laurel A.

    2005-01-01

    Terje Hillesund points out that "information technology and especially the Internet have profoundly changed the ways of publishing." Recently, the book publishing industry has started to catch up, making digitized texts--including multimedia texts--available for sale through online bookstores, and in some cases, available for free downloading.…

  20. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    CHINA'S SPACE TRAVEL On October 16, 2003 China successfully launched its first manned space flight. This book records the course of China's manned space undertaking, and development of its manned space flight. It includes 200 color plates relating to the Seven Systems of China's Manned Space Mission; Development of the

  1. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    CHINA'S SPACE TRAVEL On October 16, 2003 China successfully launched its first manned space flight. This book records the course of China's manned space undertaking, and development of its manned space flight. It includes 200 color plates relating to the Seven Systems of China's Manned Space Mission; Development of the Shenzhou Spacecraft; City of Dreams in the Gobi Desert; Yang

  2. Recommended Books

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Book 1: (Editor-in-Chief: Shi Yafeng; Published by Elsevier and Science Press Beijing in 2008, 539 pages) Glaciers and Related Environments in China Since the professional institution for glaciology attached to the Chinese Academy of Sciences was established in 1958, studies of glaciers in alpine regions, and of Quaternary glaciations throughout

  3. Book Review:

    Science.gov (United States)

    Fallone, B. G.

    2004-01-01

    This book represents the proceedings of the five day programme on IMRT techniques presented at the 2003 American Association of Physicists in Medicine (AAPM) Summer School held in Colorado Springs, Colorado. The book is essentially an overview of IMRT techniques, discussing the history, the mathematical processes involved in the planning stages, the biological indices for evaluations, the off-line and on-line medical imaging that is required, the various IMRT delivery techniques available, positioning and motion verification, shielding and QA issues, and some clinical applications. There is some additional discussion on modulated electron and proton therapy, views on the clinical and financial impact of IMRT, as well as some speculation on the future uses of IMRT. The fact that the book is an `overview' must be emphasized. Medical physicists who are well-read in IMRT, or have implemented IMRT, even partially, may be a little disappointed with the book. Although specific details were purposely omitted, the well-read physicist would have preferred to go right to the `heart of the matter', something this book fails to do. As is typical of many proceedings-type books, there is a certain level of inconsistency of writing styles, as well as some redundancy between the different chapters. It is unfortunate that such a large volume does not have an index to allow a reader to explore a particular subject pertaining to IMRT. The reader would have to guide himself/herself by the table of contents before each chapter which could be a problem if the reader requires some information quickly. It is interesting to note that the book lends itself to a variety of professionals interested in IMRT, including administrators. It may be a source of help for medical physicists who wish to discuss IMRT issues with higher level administration, for example. Some clinical applications are also reviewed. The lack of details concerning the advantages of IMRT with respect to clinical outcome is

  4. Cataloguing Rules for Books and other Media in Primary and Secondary Schools. A Simplified Version of Anglo-American Cataloguing Rules, Together with Rules for Cataloguing Non-book Materials. Fifth (Expanded) Edition.

    Science.gov (United States)

    Furlong, Norman, Comp.; Platt, Peter, Comp.

    The School Library Association (London, England) presents a brief and simplified version of the 1967 "Anglo-American Cataloguing Rules" along with cataloging rules for non-book materials based on the "Non-book Materials: Cataloguing Rules" of 1973. The 33 rules are briefly stated, and short examples are given for main entries, titles, imprint,…

  5. Book Review:

    Science.gov (United States)

    Chrusciel, P. T.

    2006-06-01

    Most of us sometimes have to face a student asking: 'What do I need to get started on this'. (In my case 'this' would typically be a topic in general relativity.) After thinking about it for quite a while, and consulting candidate texts again and again, a few days later I usually end up saying: read this chapter in book I (but without going too much detail), then that chapter in book II (but ignore all those comments), then the first few sections of this review paper (but do not try to work out equations NN to NNN), and then come back to see me. In the unlikely event that the student comes back without changing the topic, there follows quite a bit of explaining on a blackboard over the following weeks. From now on I will say: get acquainted with the material covered by this book. As far as Isham's book is concerned, 'this' in the student's question above can stand for any topic in theoretical physics which touches upon differential geometry (and I can only think of very few which do not). Said plainly: this book contains most of the introductory material necessary to get started in general relativity, or those branches of mathematical physics which require differential geometry. A student who has mastered the notions presented in the book will have a solid basis to continue into specialized topics. I am not aware of any other book which would be as useful as this one in terms of the spectrum of topics covered, stopping at the right place to get sufficient introductory insight. According to the publisher, these lecture notes are the content of an introductory course on differential geometry which is taken by first-year theoretical physics PhD students, or by students attending the one-year MSc course 'Quantum Fields and Fundamental Forces' at Imperial College, London. The volume is divided into six chapters: An Introduction to Topology Differential Manifolds Vector Fields and n-Forms Lie Groups Fibre Bundles Connections in a Bundle. It is a sad reflection on current

  6. Book Information

    Institute of Scientific and Technical Information of China (English)

    Li; Caige

    2015-01-01

    The Cultural Gene of Ancient Chinese SpaceAuthor:Zhang Jie Year:2012Publisher:Tsinghua University Press ISBN:9787302273646(413 pages,in Chinese)From multiple perspectives of ancient astronomy,cultural geography and mountain modes,etiquette culture and system,artifacts and space archaeology,traditional painting,geomantic theory,etc.,this book systematically explores the main origins,concepts,con-

  7. Book Reviews

    OpenAIRE

    Beavers, Sian; Brasher, Andrew; Buckler, Alison; Iniesto, Francisco

    2016-01-01

    The following publication contains book reviews of these titles: Seth Giddings, (2014) Gameworlds: Virtual Media and Children’s Everyday Play. New York: Bloomsbury Academic. 192 pages. ISBN-10: 1501318292. ISBN-13: 978-1501318290 Gibbons, A. S. (2014). An architectural approach to instructional design. New York: Routledge. ISBN-10: 0415807395. ISBN-13: 978-0415807395 Simone White and Michael Corbett (eds.), 2014. Doing Educational Research in Rural Settings: Methodological issues, internation...

  8. Book reviews

    OpenAIRE

    Beavers, Sian; Brasher, Andrew; Buckler, Alison; Iniesto, Franscisco

    2016-01-01

    The following publication contains book reviews of these titles: Seth Giddings, (2014) Gameworlds: Virtual Media and Children’s Everyday Play. New York: Bloomsbury Academic. 192 pages. ISBN-10: 1501318292. ISBN-13: 978-1501318290 Gibbons, A. S. (2014). An architectural approach to instructional design. New York: Routledge. ISBN-10: 0415807395. ISBN-13: 978-0415807395 Simone White and Michael Corbett (eds.), 2014. Doing Educational Research in Rural Settings: Methodological issues, internation...

  9. Book Review

    OpenAIRE

    2014-01-01

    The book by Arjen Markus is a veritable tour de force among the possibilities opened up by the latest incarnation of Fortran, the longest-lived programming language on the planet and still one of the favourites by scientific programmers. It is not an introduction to the syntax and semantics of the latest language standard: it is more of a gourmet cookbook showing off a wide range of examples of what the new features allow a daring programmer to do.

  10. Book Review

    Directory of Open Access Journals (Sweden)

    Salvatore Filippone

    2014-01-01

    Full Text Available The book by Arjen Markus is a veritable tour de force among the possibilities opened up by the latest incarnation of Fortran, the longest-lived programming language on the planet and still one of the favourites by scientific programmers. It is not an introduction to the syntax and semantics of the latest language standard: it is more of a gourmet cookbook showing off a wide range of examples of what the new features allow a daring programmer to do.

  11. Book review

    OpenAIRE

    NN,

    2003-01-01

    This book is entirely dedicated to the functional role of fungi in all kind of ecosystems, and it attempts to show how the world would function if fungi were not there. It is conceived as an introduction to the subject for students in mycology and ecology. The introductory chapters deal with fundamental themes, and define fungi, ecosystems and their interaction. The two following chapters deal with fungi and primary production, elucidating the way fungi make available nutrients, and the roles...

  12. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    CHINA'S SPACE TRAVEL On October 16, 2003 China successfully launched its first manned space flight. This book records the course of China's manned space undertaking, and development of its manned space flight. It includes 200 color plates relating to the Seven Systems of China's Manned Space Mission; Development of the Shenzhou Spacecraft; City of Dreams in the Gobi Desert; Yang Liwei-China's First Astronaut; and Chronology of the First

  13. Book Information

    Institute of Scientific and Technical Information of China (English)

    Qian; Fang

    2015-01-01

    Worlding Cities:Asian Experiments anthe Art of Being Global Author:Ananya Roy;Editor:Aihwa Ong Year:2012Publisher:Wiley-Blackwell ISBN:1405192763(376 pages,in English)From Dubai to Delhi and from Singapore to Shanghai,cities across Asia are sites of intense experiments with different ways of being global.This book intervenes in urban theory focused on established

  14. Automated visual inspection of imprinted pharmaceutical tablets

    Science.gov (United States)

    Bukovec, Marko; Špiclin, Žiga; Pernuš, Franjo; Likar, Boštjan

    2007-09-01

    This paper is on automated visual inspection of tablets that may, in contrast to manual tablet sorting, provide objective and reproducible tablet quality assurance. Visual inspection of the ever-increasing numbers of produced imprinted tablets, regulatory enforced for unambiguous identification of active ingredients and dosage strength of each tablet, is especially demanding. The problem becomes more tractable by incorporating some a priori knowledge of the imprint shape and/or appearance. For this purpose, we consider two alternative automated tablet defect detection methods. The geometrical method, incorporating geometrical a priori knowledge of the imprint shape, enables specific inspection of the imprinted and non-imprinted tablet surface, while the statistical method exploits statistical a priori knowledge of tablet surface appearance, derived from a training image database. The two methods were evaluated on a large tablet image database, consisting of 3445 images of four types of imprinted tablets, with and without typical production defects. A 'gold standard' for testing the performances of the two inspection methods was established by manually classifying the tablets into good and five defective classes. The results, obtained by ROC (receiver operating characteristics) analysis, indicate that the statistical method yields better defect detection sensitivity and specificity than the geometrical method. Both presented image analysis methods are quite general and promising tools for automated visual inspection of imprinted pharmaceutical tablets.

  15. Book Review:

    Science.gov (United States)

    Folacci, Antoine; Jensen, Bruce

    2003-12-01

    Thanks to its impressive success in the second half of the 20th century, both in high-energy physics and in critical phenomena, quantum field theory has enjoyed an abundant literature. We therefore greet yet another book on this subject with caution: what can a monograph on quantum field theory bring now that is new, either conceptually or pedagogically? But when it is written by a physicist such as Bryce DeWitt, who has made his own contribution to the collection of field theory books with The Global Approach to Quantum Field Theory, all suspicion is naturally abandoned. One knows in advance that this book can only lead to a genuine enrichment of the literature. DeWitt has made a formidable contribution to various areas of physics: general relativity, the interpretation of quantum mechanics, and most of all the quantization of non-Abelian gauge theories and quantum gravity. In addition, his pedagogical publications, especially the Les Houches schools of 1963 and 1983 [1, 2], have had a great impact on quantum field theory. All this makes the reader keen to pick up his new work and a deeper reading confirms the reviewer's initial enthusiasm. We must begin by alerting the potential readers of this book that it cannot be compared to any other book in the field (unless of course we are talking about references [1] and [2], of which the book under review is an extension and reworking). This uniqueness applies to both the scientific content and the way the ideas are presented. A quick description of this book and a brief explanation of its title should convince the reader of the book's unique quality. For DeWitt, a central concept of field theory is that of `space of histories'. For a field varphii defined on a given spacetime M, the set of all varphii(x) for all x in all charts of M defines its history. It is the space Phi of all possible histories (dynamically allowed or not) of the fields defined on M which is called the `space of histories' by DeWitt. If only

  16. Imprinting in Plants and Its Underlying Mechanisms

    Institute of Scientific and Technical Information of China (English)

    Hongyu Zhang; Abed Chaudhury; Xianjun Wu

    2013-01-01

    Genomic imprinting (or imprinting) refers to an epigenetic phenomenon by which the allelic expression of a gene depends on the parent of origin.It has evolved independently in placental mammals and flowering plants.In plants,imprinting is mainly found in endosperm.Recent genome-wide surveys in Arabidopsis,rice,and maize identified hundreds of imprinted genes in endosperm.Since these genes are of diverse functions,endosperm development is regulated at different regulatory levels.The imprinted expression of only a few genes is conserved between Arabidopsis and monocots,suggesting that imprinting evolved quickly during speciation.In Arabidopsis,DEMETER (DME) mediates hypomethylation in the maternal genome at numerous loci (mainly transposons and repeats) in the central cell and results in many differentially methylated regions between parental genomes in the endosperm,and subsequent imprinted expression of some genes.In addition,histone modification mediated by Polycomb group (PcG) proteins is also involved in regulating imprinting.DMEinduced hypomethylated alleles in the central cell are considered to produce small interfering RNAs (siRNAs) which are imported to the egg to reinforce DNA methylation.In parallel,the activity of DME in the vegetative cell of the male gametophyte demethylates many regions which overlap with the demethylated regions in the central cell.siRNAs from the demethylated regions are hypothesized to be also transferred into sperm to reinforce DNA methylation.Imprinting is partly the result of genome-wide epigenetic reprogramming in the central cell and vegetative cell and evolved under different selective pressures.

  17. Book Review:

    Science.gov (United States)

    Beenakker, C. W. J.

    2005-08-01

    Quantum Noise is advertised as a handbook, and this is indeed how it functions for me these days: it is a book that I keep within hand's reach, ready to be consulted on the proper use of quantum stochastic methods in the course of my research on quantum dots. I should point out that quantum optics, the target field for this book, is not my field by training. So I have much to learn, and find this handbook to be a reliable and helpful guide. Crispin Gardiner previously wrote the Handbook of Stochastic Methods (also published by Springer), which provides an overview of methods in classical statistical physics. Quantum Noise, written jointly with Peter Zoller, is the counterpart for quantum statistical physics, and indeed the two books rely on each other by frequent cross referencing. The fundamental problem addressed by Quantum Noise is how the quantum dynamics of an open system can be described statistically by treating the environment as a source of noise. This is a general problem in condensed matter physics (in particular in the context of Josephson junctions) and in quantum optics. The emphasis in this book in on the optical applications (for condensed matter applications one could consult Quantum Dissipative Systems by Ulrich Weiss, published by World Scientific). The optical applications centre around the interaction of light with atoms, where the atoms represent the open system and the light is the noisy environment. A complete description of the production and detection of non-classical states of radiation (such as squeezed states) can be obtained using one of the equivalent quantum stochastic formulations: the quantum Langevin equation for the field operators (in either the Ito or the Stratonovich form), the Master equation for the density matrix, or the stochastic Schrödinger equation for the wave functions. Each formulation is fully developed here (as one would expect from a handbook), with detailed instructions on how to go from one to the other. The

  18. Book Review:

    Science.gov (United States)

    Vespignani, A.

    2004-09-01

    Networks have been recently recognized as playing a central role in understanding a wide range of systems spanning diverse scientific domains such as physics and biology, economics, computer science and information technology. Specific examples run from the structure of the Internet and the World Wide Web to the interconnections of finance agents and ecological food webs. These networked systems are generally made by many components whose microscopic interactions give rise to global structures characterized by emergent collective behaviour and complex topological properties. In this context the statistical physics approach finds a natural application since it attempts to explain the various large-scale statistical properties of networks in terms of local interactions governing the dynamical evolution of the constituent elements of the system. It is not by chance then that many of the seminal papers in the field have been published in the physics literature, and have nevertheless made a considerable impact on other disciplines. Indeed, a truly interdisciplinary approach is required in order to understand each specific system of interest, leading to a very interesting cross-fertilization between different scientific areas defining the emergence of a new research field sometimes called network science. The book of Dorogovtsev and Mendes is the first comprehensive monograph on this new scientific field. It provides a thorough presentation of the forefront research activities in the area of complex networks, with an extensive sampling of the disciplines involved and the kinds of problems that form the subject of inquiry. The book starts with a short introduction to graphs and network theory that introduces the tools and mathematical background needed for the rest of the book. The following part is devoted to an extensive presentation of the empirical analysis of real-world networks. While for obvious reasons of space the authors cannot analyse in every detail all the

  19. Ferroelectric capacitor with reduced imprint

    Energy Technology Data Exchange (ETDEWEB)

    Evans, Jr., Joseph T. (13609 Verbena Pl., NE., Albuquerque, NM 87112); Warren, William L. (7716 Wm. Moyers Ave., NE., Albuquerque, NM 87122); Tuttle, Bruce A. (12808 Lillian Pl., NE., Albuquerque, NM 87122); Dimos, Duane B. (6105 Innsbrook Ct., NE., Albuquerque, NM 87111); Pike, Gordon E. (1609 Cedar Ridge, NE., Albuquerque, NM 87112)

    1997-01-01

    An improved ferroelectric capacitor exhibiting reduced imprint effects in comparison to prior art capacitors. A capacitor according to the present invention includes top and bottom electrodes and a ferroelectric layer sandwiched between the top and bottom electrodes, the ferroelectric layer comprising a perovskite structure of the chemical composition ABO.sub.3 wherein the B-site comprises first and second elements and a dopant element that has an oxidation state greater than +4. The concentration of the dopant is sufficient to reduce shifts in the coercive voltage of the capacitor with time. In the preferred embodiment of the present invention, the ferroelectric element comprises Pb in the A-site, and the first and second elements are Zr and Ti, respectively. The preferred dopant is chosen from the group consisting of Niobium, Tantalum, and Tungsten. In the preferred embodiment of the present invention, the dopant occupies between 1 and 8% of the B-sites.

  20. Book Reviews

    Directory of Open Access Journals (Sweden)

    Cyril Skinner

    1968-10-01

    Full Text Available - Soebardi, Poerwanto Danoesoegondo, Bahasa Indonesia for beginners. Sydney University Press, 1966, Book I, 160 pp. - Soebardi, J.P. Sarumpaet, The structure of bahasa Indonesia. Department of Indonesian and Malayan Studies, University of Melbourne, 1966, 167 pp. Off-set Print. - Soebardi, J.P. Sarumpaet, Introduction to Bahasa Indonesia. Melbourne University Press, 1967, 111 pp., J.A.C. Mackie (eds. - Soebardi, T.S. Lie, Introducing Indonesian. Sydney, Angus & Robertson Ltd. Book I, 1965, 115 pp. Book II, 1966, 184 pp. - A. Teeuw, Joseph Verguin, Le Malais. Essai d’analyse fonctionnelle et structurale. Cahiers de l’Homme, Ethnologie - Géographie - Linguistique. Nouvelle Série VII. Mouton & Co. Paris, La Haye 1967, 146 pp. - R. Roolvink, Cyril Skinner, The civil war in Kelantan in 1839. Monographs of the Malaysian Branch of the Royal Asiatic Society, II, 1965. vii, 175 pp., 3 maps. - H.J. de Graaf, Generale missiven van Gouverneur-Generaal en Raden aan Heren XVII der Verenidge Oostindische Compagnie. Deel III: 1655-1674. Uitgegeven door Dr. W. Ph. Coolhaas. ‘s-Gravenhage. Rijks Geschiedkundige Publicatiën. Grote Serie 125. Verkrijkbaar bij Martinus Nijhoff. 1968. - Anthony Reid, G.J. Resink, Indonesia’s history between the myths: Essays in legal history and historical theory. Selected Studies on Indonesia, Vol. 7; The Hague, Van Hoeve, 1968, 457 pp. - R.F. Beerling, S. Takdir Alisjahbana, Values as integrating forces in personality, society and culture. University of Oxford Press, Kuala Lumpur, 1966, 248 bldz.

  1. Book Review:

    Science.gov (United States)

    Fabris, Júlio C.

    2004-04-01

    General relativity is one of the cornerstones of modern physics. In spite of this, the teaching of general relativity at undergraduate level remains quite marginal. The reasons for this particular situation are quite well known. We can quote, for example, two of them: general relativity requires specific mathematical tools that are somehow outside the mainstream of undergraduate technical development; moreover, this is a branch of physics whose observational and experimental applications have remained rare until recent times, and even though this scenario has changed dramatically in the last few years, the new situation has not yet been absorbed into undergraduate teaching. However, there are many textbooks devoted to the teaching of general relativity at undergraduate level. The recent book of J B Hartle, Gravity: An Introduction to Einstein's General Relativity, is a new proposal in this sense. It is perhaps one of the most interesting pedagogical approaches seeking to surmount the difficulties that arise when one tries to include general relativity in undergraduate teaching. In this new book, Hartle attempts to address the difficuties that must be faced by anyone who teaches general relativity at undergraduate level. In order to not scare the student with the hard technical preparation needed to obtain the basic equations of general relativity, Einstein's equations, he simply gives up the idea of introducing these equations at the very beginning. Instead, he chooses to present Einstein's equations, with most of the mathematics needed to do them, in the last part of the book. This delicate (and of course dangerous) choice has the advantage of introducing the reader first to the physical aspects of general relativity. This approach can be dangerous because the relevant solutions of the equations necessary to discuss the physical content of general relativiy are presented first without a formal derivation. But the author circumvents this potential drawback in a

  2. Book Reviews

    OpenAIRE

    Redactie KITLV

    1982-01-01

    -Hoffmann Léon-Francois, J. Michael Dash, Literature and ideology in Haiti 1915-1961. London and Basingstoke: The MacMillan Press, 1981. xv + 213 pp. -Gabriel Debien, Sidney W. mINTZ, Esclave = facteur de production: l'économie politique de l'esclavage. Paris: Dunod, 1981. xvii + 271 pp. -Franklin W. Knight, Bridget Brereton, A history of modern Trinidad, 1783-1962. Kingston, Port-of-Spain, London: Heinemann Educational Books Ltd., 1981. x + 262 pp. -Donald J. Waters, Walter Rodney, A history...

  3. Electronic Books

    OpenAIRE

    Sobotková, Kateřina

    2010-01-01

    My bachelor thesis is devoted to ebooks. It elaborates on the format of ebooks and the sources from which it can be obtained. There are also analyzed the reasons why the books are digitized and the ways in which digitisation is performed. One chapter is also devoted to ebook readers and other devices and computer software on which one can read ebooks. The practical part contains the price setting of ebooks and assessment of the situation on the market for ebooks in the Czech Republic and abro...

  4. Book Review

    Directory of Open Access Journals (Sweden)

    Adrian Brown

    2011-01-01

    Full Text Available “Numerical Methods for Special Functions” by Gil, Seguar and Temme is a collection of methods and approaches for finding the most efficient and accurate ways of computing values of functions that have no general definition. “Numerical Methods for Special Functions” might appear at first glance to be a boring and perhaps dry subject for non-mathematicians, and indeed it is a little difficult to approach without being an expert in the area, but if you do find yourself in need of some hints for the best implementations available, this book might be a life saver.

  5. Golden book

    CERN Multimedia

    2004-01-01

    On 19 October, CERN reached the climax of its Jubilee with the official celebration in the presence of very high representatives of the Member and Observer States. Above, one of the high moments of the day: the signing of the golden book by the King of Spain, Juan Carlos, and at his right the Director-General of CERN, Robert Aymar, the President of the Swiss Confederation, Joseph Deiss, and the President of the Republic of France, Jacques Chirac. A complete report of this event will be in the next issue of the Bulletin.

  6. Book Reviews

    OpenAIRE

    Redactie KITLV

    1986-01-01

    -John Parker, Norman J.W. Thrower, Sir Francis Drake and the famous voyage, 1577-1580. Los Angeles: University of California Press, Contributions of the UCLA Center for Medieval and Renaissance Studies Vol. 11, 1984. xix + 214 pp. -Franklin W. Knight, B.W. Higman, Trade, government and society in Caribbean history 1700-1920. Kingston: Heinemann Educational Books, 1983. xii + 172 pp. -A.J.R. Russel-Wood, Lyle N. McAlister, Spain and Portugal in the New World, 1492-1700. Minneapolis, University...

  7. Imprinted Zac1 in neural stem cells

    Institute of Scientific and Technical Information of China (English)

    Guillaume Daniel; Udo Schmidt-Edelkraut; Dietmar Spengler; Anke Hoffmann

    2015-01-01

    Neural stem cells (NSCs) and imprinted genes playan important role in brain development. On historicalgrounds, these two determinants have been largelystudied independently of each other. Recent evidencesuggests, however, that NSCs can reset select genomicimprints to prevent precocious depletion of the stemcell reservoir. Moreover, imprinted genes like thetranscriptional regulator Zac1 can fine tune neuronalvs astroglial differentiation of NSCs. Zac1 binds ina sequence-specific manner to pro-neuronal andimprinted genes to confer transcriptional regulation andfurthermore coregulates members of the p53-familyin NSCs. At the genome scale, Zac1 is a central hub ofan imprinted gene network comprising genes with animportant role for NSC quiescence, proliferation anddifferentiation. Overall, transcriptional, epigenomic, andgenomic mechanisms seem to coordinate the functionalrelationships of NSCs and imprinted genes fromdevelopment to maturation, and possibly aging.

  8. Tailoring Imprinted Titania Nanoparticles for Purines Recognition

    Directory of Open Access Journals (Sweden)

    Adnan Mujahid

    2015-01-01

    Full Text Available Molecular imprinted titania nanoparticles were developed for selective recognition of purines, for example, guanine and its final oxidation product uric acid. Titania nanoparticles were prepared by hydrolysis of titanium butoxide as precursor in the presence of pattern molecules. The morphology of synthesized nanoparticles is evaluated by SEM images. Recognition characteristics of imprinted titania nanoparticles are studied by exposing them to standard solution of guanine and uric acid, respectively. The resultant change in their concentration is determined by UV/Vis analysis that indicated imprinted titania nanoparticles possess high affinity for print molecules. In both cases, nonimprinted titania is taken as control to observe nonspecific binding interactions. Cross sensitivity studies suggested that imprinted titania is at least five times more selective for binding print molecules than competing analyte thus indicating its potential for bioassay of purines.

  9. Book Review

    Science.gov (United States)

    Kragh, Helge

    2015-11-01

    Ever since the days of William Blake there has been an underground resistance against the soulless yet triumphant science and its unholy alliance with money, technology and political power. With the nearly undisputed hegemony that science and technological innovation has attained in the post-World War II era, this kind of resistance has resulted in numerous books and articles that in different ways warn against the dark sides of science and the socio-economic system that nourishes a science in degeneration. Classical examples include Herbert Marcuse's One-Dimensional Man (1964), Jacques Ellul's The Technological Society (1965), Theodore Roszak's The Making of a Counter Culture (1968), and Paul Feyerabend's Science in a Free Society (1978). A fair part of the literature written by sociologists and philosophers is not only critical to trends in modern science, but tends to or is overtly anti-science. The book under review belongs in some respects to this heterogeneous literary tradition, but Twilight of the Scientific Age is primarily directed against the institutional system of science and its associated ideology and not against science itself. Indeed, the author is himself a practicing scientist, an astrophysicist, and he emphasizes several times that he firmly believes in science, even that he loves it. He is not a "stupid cultural relativist," he asserts (p. 11), but a critical freethinker independent of dogmatic beliefs.

  10. The landscape of genomic imprinting across diverse adult human tissues

    Science.gov (United States)

    Baran, Yael; Subramaniam, Meena; Biton, Anne; Tukiainen, Taru; Tsang, Emily K.; Rivas, Manuel A.; Pirinen, Matti; Gutierrez-Arcelus, Maria; Smith, Kevin S.; Kukurba, Kim R.; Zhang, Rui; Eng, Celeste; Torgerson, Dara G.; Urbanek, Cydney; Li, Jin Billy; Rodriguez-Santana, Jose R.; Burchard, Esteban G.; Seibold, Max A.; MacArthur, Daniel G.; Montgomery, Stephen B.; Zaitlen, Noah A.; Lappalainen, Tuuli

    2015-01-01

    Genomic imprinting is an important regulatory mechanism that silences one of the parental copies of a gene. To systematically characterize this phenomenon, we analyze tissue specificity of imprinting from allelic expression data in 1582 primary tissue samples from 178 individuals from the Genotype-Tissue Expression (GTEx) project. We characterize imprinting in 42 genes, including both novel and previously identified genes. Tissue specificity of imprinting is widespread, and gender-specific effects are revealed in a small number of genes in muscle with stronger imprinting in males. IGF2 shows maternal expression in the brain instead of the canonical paternal expression elsewhere. Imprinting appears to have only a subtle impact on tissue-specific expression levels, with genes lacking a systematic expression difference between tissues with imprinted and biallelic expression. In summary, our systematic characterization of imprinting in adult tissues highlights variation in imprinting between genes, individuals, and tissues. PMID:25953952

  11. Book Review:

    Science.gov (United States)

    Das, Ashok

    2007-01-01

    It is not usual for someone to write a book on someone else's Ph.D. thesis, but then Feynman was not a usual physicist. He was without doubt one of the most original physicists of the twentieth century, who has strongly influenced the developments in quantum field theory through his many ingenious contributions. Path integral approach to quantum theories is one such contribution which pervades almost all areas of physics. What is astonishing is that he developed this idea as a graduate student for his Ph.D. thesis which has been printed, for the first time, in the present book along with two other related articles. The early developments in quantum theory, by Heisenberg and Schrödinger, were based on the Hamiltonian formulation, where one starts with the Hamiltonian description of a classical system and then promotes the classical observables to noncommuting quantum operators. However, Dirac had already stressed in an article in 1932 (this article is also reproduced in the present book) that the Lagrangian is more fundamental than the Hamiltonian, at least from the point of view of relativistic invariance and he wondered how the Lagrangian may enter into the quantum description. He had developed this idea through his 'transformation matrix' theory and had even hinted on how the action of the classical theory may enter such a description. However, although the brief paper by Dirac contained the basic essential ideas, it did not fully develop the idea of a Lagrangian description in detail in the functional language. Feynman, on the other hand, was interested in the electromagnetic interactions of the electron from a completely different point of view rooted in a theory involving action-at-a-distance. His theory (along with John Wheeler) did not have a Hamiltonian description and, in order to quantize such a theory, he needed an alternative formulation of quantum mechanics. When the article by Dirac was brought to his attention, he immediately realized what he was

  12. Book Review:

    Science.gov (United States)

    Poisson, E.

    2006-09-01

    The motion of a charged particle interacting with its own electromagnetic field is an area of research that has a long history; this problem has never ceased to fascinate its investigators. On the one hand the theory ought to be straightforward to formulate: one has Maxwell's equations that tell the field how to behave (given the motion of the particle), and one has the Lorentz-force law that tells the particle how to move (given the field). On the other hand the theory is fundamentally ambiguous because of the field singularities that necessarily come with a point particle. While each separate sub-problem can easily be solved, to couple the field to the particle in a self-consistent treatment turns out to be tricky. I believe it is this dilemma (the theory is straightforward but tricky) that has been the main source of the endless fascination. For readers of Classical and Quantum Gravity, the fascination does not end there. For them it is also rooted in the fact that the electromagnetic self-force problem is deeply analogous to the gravitational self-force problem, which is of direct relevance to future gravitational wave observations. The motion of point particles in curved spacetime has been the topic of a recent Topical Review [1], and it was the focus of a recent Special Issue [2]. It is surprising to me that radiation reaction is a subject that continues to be poorly covered in the standard textbooks, including Jackson's bible [3]. Exceptions are Rohrlich's excellent text [4], which makes a very useful introduction to radiation reaction, and the Landau and Lifshitz classic [5], which contains what is probably the most perfect summary of the foundational ideas (presented in characteristic terseness). It is therefore with some trepidation that I received Herbert Spohn's book, which covers both the classical and quantum theories of a charged particle coupled to its own field (the presentation is limited to flat spacetime). Is this the text that graduate students

  13. Book Review:

    Science.gov (United States)

    Borcherds, P.

    2005-03-01

    This book achieves what its subtitle indicates. The author skilfully weaves together the story of Bragg's life and of the scientific developments with which he was most closely involved. The author has a good understanding of Bragg's scientific work which he explains in considerable detail, with a number of diagrams reproduced from Bragg's papers, and manages to convey the excitement generated by Bragg's discoveries. The salient points of Bragg's life are well known. He was born and brought up in Australia and is still the youngest ever winner of a Nobel prize (though Josephson did his seminal work at a comparable age, it took many years for him to get his Prize). From 1914 to 1918 Bragg was involved with acoustic methods of detecting enemy guns. From 1919 to 1938 he was Professor of Physics in Manchester, and for about a year he was Director of the National Physical Laboratory. He then went to Cambridge as Cavendish Professor until 1953, when he moved to the Royal Institution (where his father had been). While an undergraduate at Cambridge 'Bragg's most influential teacher was...C T R Wilson [Nobel Laureate, 1927]...[whose] lectures "were the best, and delivery the worst, of any lectures to which I have ever been. He mumbled facing the board, he was very hesitant in his delivery, and yet the way he presented the subject was quite brilliant'' '. One wonders how long Wilson's inspirational teaching would survive today, with continual inspections and the requirement to satisfy the demands of the jobsworths. Bragg's comments on this would make interesting reading! Bragg was a very successful public lecturer on science. He made use of vivid analogies, many of which are quoted by Hunter. Since this book is published by Oxford University Press, I hope that some of them may appear in future editions of The Oxford Dictionary of Quotations. (Bragg is included in Mackay's A Dictionary of Scientific Quotations (Bristol: Institute of Physics Publishing)). There are too many

  14. Book Review:

    Science.gov (United States)

    Botet, R.

    2005-01-01

    This second edition of the popular book written by Quang Ho-Kim, Narenda Kumar and Chi Sing Lam, provides a comprehensive and interesting view of ten important topics in modern physics. All the sections have been updated: symmetry, lasers, superconductivity, chaos and fractals, stellar evolution, elementary particles and cosmology, while three new sections have been added to this edition: Bose-Einstein condensates, nanostructures and quantum computation. It is an impressive feat by the authors to cover such a wide panorama of physics from particles to cosmos and at a consistently high scientific level of information and explanation. This level is excellent and is at the frontier of current research but it does mean that some parts may be quite difficult for the undergraduate student. The ideal reader is probably the mature physicist revisiting familiar lines of thought, and following amazing bridges between distant topics. And if you are an active specialist in one particular topic, this book would give a clear insight on subjects outside your own field, allowing you to at last understand what your university colleague is really doing in a branch of physics with which you are totally unfamiliar. At the beginning, the style of writing can be disconcerting at this scientific level; equations are almost systematically avoided and illustrations are sparse, which can occasionally make the discussions rather ponderous, but the remarkable level of pedagogy and imaginative conception more than compensates for this. The fundamental ideas of exciting natural phenomena are elegantly discussed, while the authors never forget that physics is an experimental science, and address up-to-date applications in this manner. A brief bibliography is added at the end of each chapter, and a few simple exercises are given with answers. But the great strength of this book, and the main reason why it is worth reading by anyone interested in modern science, lies in the text itself which

  15. Book Review:

    Science.gov (United States)

    Barbour, J. B.

    2007-02-01

    These colloquium proceedings will be valuable, the blurb says, for graduate students and researchers in cosmology and theoretical astrophysics. Specifically, the book 'looks at both the strengths and weaknesses of the current big bang model in explaining certain puzzling data' and gives a 'comprehensive coverage of the expanding field of cosmology'. The reality is rather different. Conference proceedings rarely compare in value with a solid monograph or good review articles, and Current Issues in Cosmology is no exception. The colloquium was convened by the two editors, who have both long harboured doubts about the big bang, and was held in Paris in June 2004. The proceedings contain 19 presented papers and relatively brief summary comments by four panel speakers. The questions and answers at the end of each talk and a general discussion at the end were recorded and transcribed but contain little of interest. The nature of the colloquium is indicated by panellist Francesco Bertola's comment: 'While in the 1950s it was possible to speak of rival theories in cosmology, now the big-bang picture has no strong rivals. This is confirmed by the fact that out of 1500 members of the IAU Division VIII (Galaxies and the Universe) only a dozen, although bright people, devote their time to the heterodox views.' This was largely a platform for them to give their views. At least half of the dozen, all the 'usual suspects', were present: Geoffery and Margaret Burbidge, Jayant Narlikar, Halton Arp, Chandra Wickramasinghe and, in spirit only but playing a role somewhat like the ghost of Hamlet's father, the late Fred Hoyle. Doubters presented 12 of the 19 papers. Orthodoxy should certainly be challenged and the sociology of science questioned, but I found two main problems with this book. The papers putting the orthodox view are too short, even perfunctory. The most that a serious graduate student would get out of them is a reference to a far better review article or book on modern

  16. Book Review:

    Science.gov (United States)

    Webb, Steve

    2008-11-01

    The Polish physicist Józio (Joseph, Josh, Jo) Rotblat was catapulted into the public eye when he (and the 'Pugwash Conferences' organization) received the 1995 Nobel Peace Prize. His life prior to that had been most distinguished but conducted well out of the public eye. Born and raised as a Jewish physicist in pre-World War II Poland, and thus potentially educationally disadvantaged, he battled away for education and scientific achievement. He came to Liverpool University just before the outbreak of World War II, worked in James Chadwick's laboratory on the early beginnings of neutron fission physics, moved to Los Alamos to take part in the US-UK collaborative Manhattan Project to build a nuclear bomb and was motivated by a desire to rid Poland of Nazi 'racial cleansing'. On realizing the US-UK goal was somewhat wider, he resigned this work and dedicated his life to the peaceful uses of radiation and the campaigns to rid the world of the potential world-eliminating possibility of nuclear war. For this purpose he interacted with Albert Einstein and Bertrand Russell, and in July 1957 founded the 'Pugwash Conferences', named for a small fishing village in Nova Scotia, Canada where the first was held. Along the way his personal life was no less dramatic. Cruel events conspired, and his wife Tola remained in Poland and was killed in the Nazi extermination camp at Majdanek. He grieved for his beloved Poland and those left behind or unaccounted for. He was suspected by some Americans of being a spy and had his personal papers and family artefacts impounded. After the war he was Professor of Medical Physics at St Bartholomew's Hospital, London for 30 years up to retirement. After John Roberts, he was the second editor of this journal Physics in Medicine and Biology from 1961-72 (see e.g. Bob Burns' paper in our 50th birthday issue, 2006. Kit Hill's little book which chronicles the life and times of Rotblat weaves together the key events in his personal and professional

  17. An unexpected function of the Prader-Willi syndrome imprinting center in maternal imprinting in mice.

    Directory of Open Access Journals (Sweden)

    Mei-Yi Wu

    Full Text Available Genomic imprinting is a phenomenon that some genes are expressed differentially according to the parent of origin. Prader-Willi syndrome (PWS and Angelman syndrome (AS are neurobehavioral disorders caused by deficiency of imprinted gene expression from paternal and maternal chromosome 15q11-q13, respectively. Imprinted genes at the PWS/AS domain are regulated through a bipartite imprinting center, the PWS-IC and AS-IC. The PWS-IC activates paternal-specific gene expression and is responsible for the paternal imprint, whereas the AS-IC functions in the maternal imprint by allele-specific repression of the PWS-IC to prevent the paternal imprinting program. Although mouse chromosome 7C has a conserved PWS/AS imprinted domain, the mouse equivalent of the human AS-IC element has not yet been identified. Here, we suggest another dimension that the PWS-IC also functions in maternal imprinting by negatively regulating the paternally expressed imprinted genes in mice, in contrast to its known function as a positive regulator for paternal-specific gene expression. Using a mouse model carrying a 4.8-kb deletion at the PWS-IC, we demonstrated that maternal transmission of the PWS-IC deletion resulted in a maternal imprinting defect with activation of the paternally expressed imprinted genes and decreased expression of the maternally expressed imprinted gene on the maternal chromosome, accompanied by alteration of the maternal epigenotype toward a paternal state spread over the PWS/AS domain. The functional significance of this acquired paternal pattern of gene expression was demonstrated by the ability to complement PWS phenotypes by maternal inheritance of the PWS-IC deletion, which is in stark contrast to paternal inheritance of the PWS-IC deletion that resulted in the PWS phenotypes. Importantly, low levels of expression of the paternally expressed imprinted genes are sufficient to rescue postnatal lethality and growth retardation in two PWS mouse models

  18. Interactive Collaborative Books

    OpenAIRE

    Al-Mutawa, Abdullah M.

    2007-01-01

    Books are one of the most important tools to convey knowledge, they survived to be a convenient and portable source of information. On the other side, Electronic books (e-books) are playing a big role in attracting a huge number of readers, but still paper books are preferable by many people due to some drawbacks in e-books. Yet, Interactive books combines all positive features in ordinary books as well as e-books, the author is introducing a new Interactive Collaborative book that might chan...

  19. The Economics of Books

    NARCIS (Netherlands)

    Canoy, M.F.M.; van Ours, J.C.; van der Ploeg, F.

    2005-01-01

    The tensions between books and book markets as expressions of culture and books as products in profit-making businesses are analysed and insights from the theory of industrial organisation are given.Governments intervene in the market for books through laws concerning prices of books, grants for aut

  20. Book Reviews

    Directory of Open Access Journals (Sweden)

    J. van Goor

    1997-07-01

    Full Text Available - Peter Boomgaard, Christine Dobbin, Asian entrepreneurial minorities; Conjoint communities in the making of the world economy, 1570-1940. Richmond: Curzon Press, 1996, xiii + 246 pp. [Nordic Institute of Asian Studies Monograph Series 71.] - Ian Brown, Fukuda Shozo, With sweat and abacus; Economic roles of Southeast Asian Chinese on the eve of World War II, edited by George Hicks. Singapore: Select Books, 1995, xii + 246 pp. - Ian Brown, George Hicks, Chinese organisations in Southeast Asia in the 1930s. Singapore: Select Books, 1996, xv + 168 pp. - Matthew I. Cohen, Laurie J. Sears, Shadows of empire; Colonial discourse and Javanese tales. Durham/London: Duke University Press, 1996, xxi + 349 pp. - J. van Goor, Anthony Reid, Southeast Asia in the age of commerce 1450-1680. Vol. II: Expansion and crisis. New Haven/London: Yale University Press, 1993, xv + 390 pp. - J. van Goor, Anthony Reid, Southeast Asia in the age of commerce 1450-1680. Vol. I: The lands below the winds. New Haven/London: Yale University Press, 1988, xvi + 275 pp. - David Henley, Saya S. Shiraishi, Young heroes; The Indnesian family in politics. Ithaca/New York: Southeast Asia Program, Cornell University, Southeast Asia Program Publications, 1997, 183 pp. [Studies on Southeast Asia 22.] - Gerrit Knaap, P. Jobse, Bronnen betreffende de Midden-Molukken 1900-1942. Den Haag: Instituut voor Nederlandse Geschiedenis, 1997. 4 volumes. Rijks Geschiedkundige Publicatiën, Kleine Serie, 81, 82, 83, 84. Volume 1 bewerkt door P. Jobse, 2 en 3 door Ch.F. van Fraassen, 4 door Ch.F van Fraassen en P. Jobse. xii + 578, xii + 578, xii + 711, x + 655, xi + 261 pp., Ch. F. van Fraassen (eds. - Indro Nugroho-Heins, Clara Brakel-Papenhuyzen, Classical Javanese dance; The Surakarta tradition and its terminology. Leiden: KITLV Press, 1995, xi + 252 pp. [Verhandelingen 155.] - László Sluimers, Shigeru Sato, War, nationalism and peasants; Java under the Japanese occupation, 1942-1945. Armonk, New

  1. Book Reviews

    Directory of Open Access Journals (Sweden)

    S. Kooijman

    1958-07-01

    Full Text Available - F.D.K. Bosch, J.G. de Casparis, Prasasti Indonesia diterbitkan oleh Dinas Purbakala Republik Indonesia 11. - Selected Inscriptions from the 7th to the 9th century A.D., Masa Baru, Bandung, 1956, 395 pp. - Rodney Needham, Louis Dumont, Une sous-caste de l’Inde du Sud: organisation sociale et religion des Pramalai Kallar. Paris 1957 (École Pratique des Hautes Etudes. vi + 460 pp., 38 photographic plates, 24 figures, maps. - J. van Baal, Erhard Schlesier, Die Melanesischen Geheimkulte. Untersuchung über ein Grenzgebiet der ethnologischen Religions - und Gesellschaftsforschung und zur Siedlungsgeschichte Melanesiens; Habilitationsschrift d. Universität Göttingen; Musterschmidt-Verlag, Göttingen 1958; 390 pag. - A.J.F. Köbben, E. Adamson Hoebel, Man in the primitive world; an introduction to anthropology. Mc-Graw-Hill Book Company, New York etc. 1958; 2e herziene druk. 678 pp. - S. Kooijman, P. van Emst, Geld in Melanesië. De functie van het monetaire element in een primitieve maatschappij. Dissertatie Amsterdam. Amsterdam, 1954. - S. Kooijman, Thor Heyerdahl, Aku-aku. Het mysterie van Paaseiland. Lochem, z.j. (Vertaling uit het Noors door N.G. Visser, H.D. Baars en Greta Baars-Jelgersma.

  2. Book Reviews

    Directory of Open Access Journals (Sweden)

    Alistair Lamb

    1964-10-01

    Full Text Available - B.V.A. Röling, Paul Shepard, Psycholex. Megwa, New York, 1960. 144 blz. - L. Sluimers, J.F. Cady, Southeast Asia: Its historical development. New York etc., McGraw-Hill Book Company, 1964. XVII, 657, IX blz., foto, krtn. - H.J. de Graaf, Nicholas Tarling, Piracy and politics in the Malay world. A study of British imperialism in nineteenth-century Sout-East Asia. F.W. Cheshire, Melbourne, Canberra, Sydney, 1963. 273 pp., frontispiece, endpaper maps. - W. Brand, N.A. Simoniya, Overseas Chinese in Southeast Asia - A Russian study. Data Paper Number 45, Southeast Asia Program, Department of Far Eastern Studies, Cornell University Press, Ithaca, New York, December 1961, 151 blz. - B.H.M. Vlekke, Alistair Lamb, The China-India border, The origins of the disputed boundaries. Published for the Royal Institute of International Affairs by Oxford University Press, London 1964, XVI + 192 pp. - R.S. Karni, Beda Lim, Malaya, a background bibilography. Journal Malayan Branch, RAS, vol. XXXV, pts. 2 & 3, 1962; V. 199 pp. - L. Sluimers, R.K. Goldsen, Factors related to acceptance of innovation in Bang Chan, Thailand; Analysis of a survey conducted by the Cornell Cross-cultural Methodology Project, May 1955. Cornell Thailand Project Interim Report Series no. 3. Data Paper: No. 25 Southeast Asia Program Department of Far Eastern Studies Cornell University. 3de druk, Ithaca, Cornell University Press, 1963. VIII, 72, X blz., M. Rallis (eds.

  3. NEW BOOKS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Qing Dynasty Archives On the Dalai lamasThe Dalai Lama was one of the two leaders of the Gelug (Yellow) Sect of Tibetan Buddhism. It won the honorific title of the Dalai lama in 1653 from Qing Emperor Shunzhi, and the Living Buddha had since been following the reincarnation system under the supervision of the Central Government. His soul boy was not legal until he won the confirmation of the Central Government. Whenever there is the need not to go through the set system, Central Government permission is a must.The Dalai Lama also did his best to seek authorization of the Central Government which would therefore issue him certificate of authority and seal of power.All these were recorded in archives, part of which are contained in the book. Its major chapters contain 154 pieces of archives related with certification of the Dalai Lama and the Panchen Erdeni under the reign of Qing Emperor Shunzhi, the demise of the Dalai Lama and the Panchen Erdeni, efforts made to look for their soul boys, selection of th

  4. Book Review:

    Science.gov (United States)

    Stewart, J. M.

    2006-02-01

    In 1952, Mme Yvonne Choquet-Bruhat published a major paper, Théorème d'existence pour certains systèmes d'équations aux dérivées partielles non linéaires (Acta Math. 88 141-225), which laid the foundation for modern studies of the Cauchy problem in general relativity. The fiftieth anniversary of this event was celebrated with an eponymous Cargèse Summer School in 2002. The proceedings of that summer school are summarized electronically (as audio, video, transparencies and lecture notes, where available) on a DVD archive included with this volume, and are also available on the internet. However the organizers decided that a separate volume describing the 'state of the art in mathematical general relativity' would be useful, and this book is the result. It includes some material not covered in the school and excludes some school material which has been covered adequately elsewhere. Unfortunately, I was unable to find, electronically, a table of contents, which every prospective purchaser would wish to see, and so this review does in fact list all the articles, ordered, roughly, by length. About one fifth of the book is devoted to a survey of Smoothness at Null Infinity and the Structure of Initial Data by Helmut Friedrich. This is a modern study of gravitational radiation, and the analysis of Einstein's equations. It is extremely helpful to survey all of this material, including some of the latest developments, using a consistent notation. This article is strongly recommended to anyone hoping to gain a foothold in this area. Note also that 47 pages of transparencies have become 84 book pages. Lars Andersson has surveyed, in The Global Existence Problem in General Relativity, some results and conjectures about the global properties of 3+1-dimensional spacetimes with a compact Cauchy surface. Again it is very useful to have essentially all of the known results presented in a consistent notation. This material is not on the DVD. Yvonne Choquet-Bruhat has

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Hans Antlöv

    1996-04-01

    , vii + 231 pp., Ulricht Mai (eds. - Tineke Hellwig, Brigitte Müller, Op de wipstoel; De niet-gewettigde inheemse vrouw van de blanke Europeaan in Nederlands-Indië (1890-1940; Een literatuuronderzoek naar beeldvorming en werkelijkheid. Amsterdam: Vakgroep Culturele Antropologie/Sociologie der Niets-Westerse Samenlevingen, 1995, xii + 131 pp. - Jan van der Putten, Liaw Yock Fang, Standard Malay made simple. Singapore: Times Books International, 1988. - Jan van der Putten, Liaw Yock Fang, Standard Indonesian made simple, written with the assistance of Nini Tiley-Notodisuryo, Singapore: Times Books International, 1990. - Jan van der Putten, Liaw Yock Fang, Speak standard Malay; A beginner’s guide. Singapore: Times Books International, 1993, xxii + 280 pp. - Jan van der Putten, Liaw Yock Fang, Speak Indonesian; A beginner’s guide, written in collaboration with Munadi Padmadiwiria and Abdullah Hassan. Singapore: Times Books International, 1990. - Alle G. Hoekema, Chr.G.F. de Jong, Geschiedenis van de Nederlandse Zending op Zuid-Sulawesi 1852-1966; Een bronnenpublicatie. Oegstgeest: Raad voor de Zending der Nederlands Hervormde Kerk, 1995, xi + 524 pp. - George Hotze, Ronald G. Gill, De Indische stad op Java en Madura; Een morfologische studie van haar ontwikkeling. Delft: Publikatieburo Bouwkunde, Technische Universiteit Delft, 1995, 350 pp. - H.A.J. Klooster, Holk H. Dengel, Neuere Darstellung der Geschichte Indonesiens in Bahasa Inonesia; Entwicklung und Tendenzen der indonesischen Historiographie. Stuttgart: Steiner, 1994, vii + 269 pp. - Harry A. Poeze, Hans Antlöv, Imperial policy and Southeast Asian nationalism 1930-1957. Richmond: Curzon Press, 1995, xiii + 323 pp., Stein Tonnesson (eds. - P.W. Preston, Michael Hill, The politics of nation building and citizenship in Singapore. London: Routledge, 1995, x + 285 pp., Lian Kwen Fee (eds. - J.W. (Pim Schoorl, Michael Southon, The navel of the perahu; Meaning and values in the maritime trading economy of a Butonese

  6. Molecularly imprinted polymers for biomedical and biotechnological applications

    Science.gov (United States)

    Dmitrienko, E. V.; Pyshnaya, I. A.; Martyanov, O. N.; Pyshnyi, D. V.

    2016-05-01

    This survey covers main advances in the preparation and application of molecularly imprinted polymers which are capable of specific recognition of biologically active compounds. The principles underlying the production of highly efficient and template-specific molecularly imprinted polymers are discussed. The focus is on the imprinting of highly structured macromolecular and supramolecular templates. The existing and potential applications of molecularly imprinted polymers in various fields of chemistry and molecular biology are considered. The bibliography includes 261 references.

  7. Molecularly Imprinted Polymer/Metal Organic Framework Based Chemical Sensors

    Directory of Open Access Journals (Sweden)

    Zhenzhong Guo

    2016-10-01

    Full Text Available The present review describes recent advances in the concept of molecular imprinting using metal organic frameworks (MOF for development of chemical sensors. Two main strategies regarding the fabrication, performance and applications of recent sensors based on molecularly imprinted polymers associated with MOF are presented: molecularly imprinted MOF films and molecularly imprinted core-shell nanoparticles using MOF as core. The associated transduction modes are also discussed. A brief conclusion and future expectations are described herein.

  8. Traditional to Digital Books

    Institute of Scientific and Technical Information of China (English)

    JING XIAOLEI

    2010-01-01

    @@ A book fair wouldn't be a book fair without books.And while the number of book fairs in China has increased in recent years,the Guangzhou Book Fair has been helping to redefine the very nature of books by promoting digital works and reading technology.This year,the fair again set up an exclusive digital reading experience exhibition hall to showcase the host province's latest achievements in the field.

  9. Book Review:

    Science.gov (United States)

    Altschul, Brett D.

    2007-06-01

    All the physics we observe in our world is underlain by special relativity, a theory that has survived for more than a hundred years, in many respects completely intact. Yet despite its status as the most stringently tested theory in all of physics, special relativity is still frequently questioned. In the last decade and a half, many scientists have come to believe that special relativity, as Einstein formulated it, will need to be modified to accommodate a quantum theory of gravity. {\\it Special Relativity: Will it Survive the Next 101 Years?} is a volume intended to introduce the reader to this new and still slightly controversial area of research. The book is divided into four parts. The first part is essentially historical. It consists of an essay discussing Einstein's work in the context of contemporary technological developments and a amusing note by R W P Drever on a precision Lorentz test that he performed literally in his backyard. These set the stage for the more modern material that follows. Part II discusses the theory of relativity and its mathematical foundations, from completely modern perspectives. There is much here that may be new even for experts on special relativity, and a significant level of mathematical sophistication on the part of the reader is assumed. A number of the lectures delve into the crucial question of how special relativity and its generalizations can be combined with quantum mechanics. The third part discusses theoretical models of Lorentz violation, and all the important paradigms that appear in the current literature are considered. These include the standard model extension (an effective field theory), modified dispersion relations and 'double special relativity', and noncommutative geometry. These lectures generally delve into less detail than those in part II; the focus is on helping the reader digest the new principles that must arise in theories without Lorentz symmetry. The final part of the volume covers current

  10. Book reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2010-09-01

    upland Southeast Asia. (Guido Sprenger Guido Sprenger, Die Männer, die den Geldbaum fällten; Konzepte von Austausch und Gesellschaft bei den Rmeet von Takheung, Laos. (Oliver Tappe Review Essay Two books on East Timor. Carolyn Hughes, Dependent communities; Aid and politics in Cambodia and East Timor. David Mearns (ed., Democratic governance in Timor-Leste; Reconciling the local and the national. (Helene van Klinken Review Essay Two books on Islamic terror Zachary Abuza, Political Islam and violence in Indonesia. Noorhaidi Hasan, Laskar jihad; Islam, militancy, and the quest for identity in post-New Order Indonesia. (Gerry van Klinken Korte Signaleringen Janneke van Dijk, Jaap de Jonge en Nico de Klerk, J.C. Lamster, een vroege filmer in Nederlands-Indië. Griselda Molemans en Armando Ello, Zwarte huid, oranje hart; Afrikaanse KNIL-nazaten in de diaspora. Reisgids Indonesië; Oorlogsplekken 1942-1949. Hilde Janssen, Schaamte en onschuld; Het verdrongen oorlogsverleden van troostmeisjes in Indonesië. Jan Banning, Comfort women/Troostmeisjes. (Harry Poeze

  11. Book Reviews

    Directory of Open Access Journals (Sweden)

    Adrianus Koster

    1981-01-01

    Full Text Available - H.J.M. Claessen, David Lewis, From Maui to Cook: The discovery and settlement of the Pacific, Drawings by Walter Stackpool. Sydney: Doubleday, 1977. Bibliography. - P. van Emst, Carl Lumholtz, Among Cannibals. An account of four years travel in Australia and of camp life with the aborigines of Queensland. Firle: Caliban Books. 383 pp. Maps, illustrations and index. Reprinted from the first edition, London: John Murray. - D.C. Geirnaert-Martin, Robert Wessing, Cosmology and social behaviour in a West Javanese settlement, Papers in International Studies, Southeast Asia Series no. 47, Ohio University Center for International Studies, Southeast Asia Program, 1978, Athens, Ohio. - B.G. Grijpstra, William Wood, Cultural-ecological perspectives in Southeast Asia, edited and with an introduction by William Wood, Papers in International Studies, Southeast Asia Studies no. 41, Ohio University Center for International Studies, Southeast Asia Program, 1977, Athens, Ohio. - R. Hagesteijn, M. Jacq-Hergoualc’h, L’armement et l’organisation de l’armée khmère aux XIIe et XIIIe siècles; d’après les bas-reliefs d’Angkor Vat, du Bayon et de Bantay Chmar. Paris: Presses Universitaires de France. - C.K. Jonker-de Putter, John Ingleson, Road to exile; The Indonesian nationalist movement, 1927-1934. ASAA Southeast Asia Publications Series, No. 1. Heinemann Educational Books (Asia Ltd., Singapore, 1979. xii + 254 blz. Bibliographie, index. - P.E. de Josselin de Jong, Roland Werner, Jah-het of Malaysia: art and culture, 1975. Kuala Lumpur: Penerbit Universiti Malaya. xxxv, 626 pp., 39 figs., 2 maps, 746 plates. - P.E. de Josselin de Jong, Roland Werner, Mah-Meri of Malaysia: Art and culture, 1974. Kuala Lumpur: Penerbit Universiti Malaya. xxvi, 485 pp., 13 figs., 3 maps, 460 plates. - Simon Kooijman, Peter Gathercole, The art of the Pacific Islands. National Gallery of Art, Washington, 1979, 365 pp., 386 illustrations + 6 sketch-maps., Adrienne L

  12. Book Review:

    Science.gov (United States)

    Carlip, S.

    2006-10-01

    The early 1980s, when I first learned theory, were desperate times for graduate students. We searched frantically for coherent introductions, passing tattered copies of review articles around like samizdat, struggling over obscure references to ancient models of strong interactions, and flocking to lectures—not least those by Joe Polchinski—that promised to really explain what was going on. If only this book had been around, it would have saved much grief. Volume I, The Bosonic String, offers a clear and well organized introduction to bosonic string theory. Topics range from the 'classical' (spectra, vertex operators, consistency conditions, etc.) to the 'modern' (D-branes first appear in an exercise at the end of chapter 1, noncommutative geometry shows up in chapter 8). Polchinski does not hesitate to discuss sophisticated matters—path integral measures, BRST symmetries, etc.—but his approach is pedagogical, and his writing is lucid, if sometimes a bit terse. Chapters end with problems that are sometimes difficult but never impossible. A very useful annotated bibliography directs readers to resources for further study, and a nearly 30-page glossary provides short but clear definitions of key terms. There is much here that will appeal to relativists. Polchinski uses the covariant Polyakov path integral approach to quantization from early on; he clearly distinguishes Weyl invariance from conformal invariance; he is appropriately careful about using complex coordinates on topologically nontrivial manifolds; he keeps the string world sheet metric explicit at the start instead of immediately hiding it by a gauge choice. Volume II includes an elegant introduction to anticommuting coordinates and superconformal transformations. A few conventions may cause confusion—%, Polchinski's stress energy tensor, for instance, differs from the standard general relativistic definition by a factor of -2π, and while this is briefly mentioned in the text, it could easily be

  13. Book Reviews

    Directory of Open Access Journals (Sweden)

    Yu. V. Maretin

    1975-01-01

    Full Text Available - J. Prins, Buiten de grenzen, sociologische opstellen aangeboden aan Prof. Dr. W.F. Wertheim, benevens een “bibliografie van de geschriften van W.F. Wertheim”. Boom, Meppel 1971. 365 blz. - H.C.G. Schoenaker, Ethnologische Zeitschrift Zuerich I, 1972. Festschrift Alfred Steinmann. Verlag Herbert Lang & Cie A.G., Bern. 397 pp. - J.C. Neuteboom, Harald Eidheim, Aspects of the Lappish minority situation. Universitetsforlaget, Oslo 1971. 86 pags. Fig. - H.J.M. Claessen, Paul Ottino, Rangiroa; parenté étendue, résidence et terres dans un atoll ploynésien. Editions Cujas. Paris 1972. 530 p. Bibl., appendices, 37 fig. en kaarten, registers. - David S. Moyer, Adelin Linton, Ralph Linton. Leaders of Modern Anthropological Series, American University Publishers Group. London 1971, pp. 196., C. Wagley (eds. - R.A.M. van Zantwijk, Carlo J.E. Gay, Chalcacingo. Drawings by Frances Pratt. Akademische Druck- und Verlagsanstalt. Graz 1971. 119 blz., geïll., XXIV fotopag. - P. van Emst, Yu. V. Maretin, Countries and peoples of the East. Vol. XIII, Countries and peoples of the Pacific Basin. Book 2. Nauka Publishing House. Central Department of Oriental Literature. Moscow 1972. (Strany i narody vostoka. Pod obscej redakciej D.A. Ol’derogge. Vypusk XIII. Strany i narody bassejna Tichogo Okeana. Kniga 2. - H. van Mierlo, Atlantische Commissie, De school en het buitenlands beleid IX. De internationale politieke vormingstaak van de school. Atlantische Commissie, Den Haag 1970, 56 blz. - Geert A. Banck, Philip Staniford, Pioneers in the tropics. The political organization of Japanese in an immigrant community in Brazil. London School of Economics Monographs on Social Anthropology no. 45. London; The Athlone Press. 1973. xvi + 201 pag.

  14. Book Reviews

    Directory of Open Access Journals (Sweden)

    J.G. Oosten

    1980-10-01

    Full Text Available - M.A. van Bakel, Frederic L. Pryor, The origins of the economy. A comparative study of distribution in primitive and peasant economies. Academic Press, New York 1977. XVIII + 475 blz. - H.J. de Graaf, W. Ph. Coolhaas, Generale missiven van Gouverneurs-Generaal en Raden aan heren XVII der Verenigde Oost-Indische Compagnie. Deel VII. 1713-1725. ‘s-Gravenhage 1979. Rijks geschiedkundige publicatiën. Grote Serie 164. - F.G.P. Jaquet, P. Sutikno, J. Bastin, Nineteenth century prints and illustrated books of Indonesia; with particular reference to the print collection of the Tropenmuseum, Amsterdam; a descriptive bibliography. Utrecht etc., Het Spectrum, 1979. XIV, 386 pp. Ills., B. Brommer (eds. - S. Kooijman, Adrienne L. Kaeppler, “Artificial curiosities” being an exposition of native manufactures collected on the three Pacific voyages of Captain James Cook, R.N. at the Bernice Pauahi Bishop Museum January 18, 1978 - August 31, 1978 on the occasion of the Bicentennial of the European discovery of the Hawaiian islands by Captain Cook - January 18, 1778. Bernice P. Bishop Museum special publication 65, Honolulu, Hawaii, 1978. - J.G. Oosten, Marcel Mauss, Seasonal variations of the Eskimo. A study in social morphology. Marcel Mauss in collaboration with Henri Beuchat. Translated, with a foreword by James J. Fox. Routledge & Kegan Paul, London, Boston and Henley 1979. - Jérôme Rousseau, W.F. Schneeberger, Contributions to the ethnology of central Northeast Borneo (parts of Kalimantan, Sarawak and Sabah. The University of Berne, Institute of Ethnology, Berne 1979. Series: Studia ethnologica Bernensia, no. 2. 143 pages. Maps, figures, plates.

  15. Book Review:

    Science.gov (United States)

    Borcherds, P. H.

    2004-09-01

    There is a new tradition in England called Apple Day which is held on some day in October. The actual day varies from place to place. For instance, in 2003, 23 October was Apple Day at Woolsthorpe Manor, the house where Isaac Newton was born and where, during the Plague, he is said to have developed the theory of gravity. (For information on future Apple Days see, for example, http://www.nationaltrust.org.uk/main/thingstodo.) Last year in our garden we picked an apple which weighed one pound, thirteen and a half ounces (1 lb 13 1/2 oz or 29 1/2 oz). The following day we went to an Apple Day event where there were many exotic apples on display, varieties which are not sold in shops. One of the varieties there was called 'Twenty Ounce'. By now you may be wondering what all this has to do with the book being reviewed. We shall return to this later. This entertaining book is ostensibly about units, in particular about Imperial and metric units, but there are numerous informative digressions. The author reminds us that almost every country 'with the exception of the United States, North and South Yemen, Burma and Brunei' has gone metric. He points out that the United States (US) became officially metric in 1893. However, as early as 1866, the US legal definition of the metre was 39.370000 inches. He tells us that after World War II the (US) inch was rounded down (from 25.400051) to 25.4 mm. There is no mention that the Imperial (British) inch was simultaneously rounded up from 25.399956 mm to 25.4 mm. The author frequently digresses, covering such matters as the trisection of angles and Eratosthenes' graphic solution for duplicating the cube. There is an informative discussion on the length of the day: appropriately 25 December, which lasts for 24 h and 30 s, is the longest day. He shows how with cycles and epicycles one can construct an ellipse. Ptolemy did not realize the importance of the focus of the ellipse. The author discusses various topics in the development of

  16. Book Review:

    Science.gov (United States)

    Parthasarathy, R.

    2005-06-01

    This book gives a clear exposition of quantum field theory at the graduate level and the contents could be covered in a two semester course or, with some effort, in a one semester course. The book is well organized, and subtle issues are clearly explained. The margin notes are very useful, and the problems given at the end of each chapter are relevant and help the student gain an insight into the subject. The solutions to these problems are given in chapter 12. Care is taken to keep the numerical factors and notation very clear. Chapter 1 gives a clear overview and typical scales in high energy physics. Chapter 2 presents an excellent account of the Lorentz group and its representation. The decomposition of Lorentz tensors under SO(3) and the subsequent spinorial representations are introduced with clarity. After giving the field representation for scalar, Weyl, Dirac, Majorana and vector fields, the Poincaré group is introduced. Representations of 1-particle states using m2 and the Pauli Lubanski vector, although standard, are treated lucidly. Classical field theory is introduced in chapter 3 and a careful treatment of the Noether theorem and the energy momentum tensor are given. After covering real and complex scalar fields, the author impressively introduces the Dirac spinor via the Weyl spinor; Abelian gauge theory is also introduced. Chapter 4 contains the essentials of free field quantization of real and complex scalar fields, Dirac fields and massless Weyl fields. After a brief discussion of the CPT theorem, the quantization of electromagnetic field is carried out both in radiation gauge and Lorentz gauge. The presentation of the Gupta Bleuler method is particularly impressive; the margin notes on pages 85, 100 and 101 invaluable. Chapter 5 considers the essentials of perturbation theory. The derivation of the LSZ reduction formula for scalar field theory is clearly expressed. Feynman rules are obtained for the λphi4 theory in detail and those of QED

  17. Book reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1992-07-01

    W. Collinwood ,Modern Bahamian society. Parkersburg IA: Caribbean Books, 1989. 278 pp., Steve Dodge (eds -Peter Hulme, Pierrette Frickey, Critical perspectives on Jean Rhys. Washington DC: Three Continents Press, 1990. 235 pp. -Alvina Ruprecht, Lloyd W. Brown, El Dorado and Paradise: Canada and the Caribbean in Austin Clarke's fiction. Parkersburg IA: Caribbean Books, 1989. xv + 207 pp. -Ineke Phaf, Michiel van Kempen, De Surinaamse literatuur 1970-1985: een documentatie. Paramaribo: Uitgeverij de Volksboekwinkel, 1987. 406 pp. -Genevieve Escure, Barbara Lalla ,Language in exile: three hundred years of Jamaican Creole. Tuscaloosa AL: University of Alabama Press, 1990. xvii + 253 pp., Jean D'Costa (eds -Charles V. Carnegie, G. Llewellyn Watson, Jamaican sayings: with notes on folklore, aesthetics, and social control.Tallahassee FL: Florida A & M University Press, 1991. xvi + 292 pp. -Donald R. Hill, Kaiso, calypso music. David Rudder in conversation with John La Rose. London: New Beacon Books, 1990. 33 pp. -Mark Sebba, John Victor Singler, Pidgin and creole tense-mood-aspect systems. Amsterdam and Philadelphia: John Benjamins, 1990. xvi + 240 pp. -Dale Tomich, Pedro San Miguel, El mundo que creó el azúcar: las haciendas en Vega Baja, 1800-873. Río Piedras, Puerto Rico: Ediciones Huracán, 1989. 224 pp. -César J. Ayala, Juan José Baldrich, Sembraron la no siembra: los cosecheros de tabaco puertorriqueños frente a las corporaciones tabacaleras, 1920-1934. Río Piedras, Puerto Rico: Ediciones Huracán, 1988. -Robert Forster, Jean-Michel Deveau, La traite rochelaise. Paris: Kathala, 1990. 334 pp. -Ernst van den Boogaart, Johannes Menne Postma, The Dutch in the Atlantic slave trade, 1600-1815. Cambridge: Cambridge University Press, 1990. xiv + 428 pp. -W.E. Renkema, T. van der Lee, Plantages op Curacao en hun eigenaren (1708-1845: namen en data voornamelijk ontleend aan transportakten. Leiden, the Netherlands: Grafaria, 1989. xii + 87 pp. -Mavis C. Campbell, Wim

  18. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1992-01-01

    Full Text Available -Selwyn R. Cudjoe, John Thieme, The web of tradition: uses of allusion in V.S. Naipaul's fiction, -A. James Arnold, Josaphat B. Kubayanda, The poet's Africa: Africanness in the poetry of Nicolás Guillèn and Aimé Césaire. Westport CT: Greenwood, 1990. xiv + 176 pp. -Peter Mason, Robin F.A. Fabel, Shipwreck and adventures of Monsieur Pierre Viaud, translated by Robin F.A. Fabel. Pensacola: University of West Florida Press, 1990. viii + 141 pp. -Alma H. Young, Robert B. Potter, Urbanization, planning and development in the Caribbean, London: Mansell Publishing, 1989. vi + 327 pp. -Hymie Rubinstein, Raymond T. Smith, Kinship and class in the West Indies: a genealogical study of Jamaica and Guyana, Cambridge: Cambridge University Press, 1988. xiv + 205 pp. -Shepard Krech III, Richard Price, Alabi's world, Baltimore and London: Johns Hopkins University Press, 1990. xx + 445 pp. -Graham Hodges, Sandra T. Barnes, Africa's Ogun: Old world and new, Bloomington & Indianapolis: Indiana University Press, 1989. xi + 274 pp. -Pamela Wright, Philippe I. Bourgois, Ethnicity at work: divided labor on a Central American banana plantation, Baltimore MD: John Hopkins University Press, 1989. xviii + 311 pp. -Idsa E. Alegría-Ortega, Andrés Serbin, El Caribe zona de paz? geopolítica, integración, y seguridad, Caracas: Editorial Nueva Sociedad, 1989. 188 pp. (Paper n.p. [Editor's note. This book is also available in English: Caribbean geopolitics: towards security through peace? Boulder CO: Lynne Rienner, 1990. -Gary R. Mormino, C. Neale Ronning, José Martí and the émigré colony in Key West: leadership and state formation, New York; Praeger, 1990. 175 pp. -Gary R. Mormino, Gerald E. Poyo, 'With all, and for the good of all': the emergence of popular nationalism in the Cuban communities of the United States, 1848-1898, Durham NC: Duke University Press, 1989. xvii + 182 pp. -Fernando Picó, Raul Gomez Treto, The church and socialism in Cuba, translated from

  19. Book Review:

    Science.gov (United States)

    Fulling, S. A.

    2006-05-01

    saying that gravity was not only an honourable member of the forces of nature, but ultimately the source of them all. It has become a cliche that the unification of relativity with quantum theory is the central problem of contemporary physics. In the 1950s, before strings, non-Abelian monopoles, or even quasars, Bryce DeWitt was applying the quantum-field-theoretical methods and conceptual framework of his mentor, Julian Schwinger, to gravity. His central insight was that the conceptual and technical problems of quantum gravity were closely analogous to those of gauge theories. He developed a unified, relentlessly abstract, and highly personal vision of the fundamentals of physical theory. It was, and is, expressed in idiosyncratic and condensed notation often different from the languages of mainstream field theorists, traditional relativists, and mathematicians alike. In short, he has never been easy reading. His ideas were systematically presented in famous lecture series at the Les Houches summer schools on Relativity, Groups and Topology in 1963 [1] and 1983 [2], the book Supermanifolds [3], and a number of (relatively) shorter expositions that have been widely read. By the middle 1970s the methods that he had developed mainly for gravity were widely recognized as very useful for Yang Mills gauge theories, and his work had become part of the mainstream. Now, another 20 years after the second Les Houches, we have this final testament of Bryce DeWitt's ideas. At over 1000 pages in two volumes in a fabric-covered slipcase, it is the sort of work usually described as 'magisterial' (meaning, perhaps, 'no one has yet succeeded in reading it all the way through'). Over the years, of course, DeWitt learned many new things and thought of ways to say the old things better. Accordingly, the new books consist of reworkings of the most important parts of the older writings together with some new material. Oxford University Press is to be thanked and congratulated for the care it

  20. Genomic imprinting and the social brain.

    Science.gov (United States)

    Isles, Anthony R; Davies, William; Wilkinson, Lawrence S

    2006-12-29

    Genomic imprinting refers to the parent-of-origin-specific epigenetic marking of a number of genes. This epigenetic mark leads to a bias in expression between maternally and paternally inherited imprinted genes, that in some cases results in monoallelic expression from one parental allele. Genomic imprinting is often thought to have evolved as a consequence of the intragenomic conflict between the parental alleles that occurs whenever there is an asymmetry of relatedness. The two main examples of asymmetry of relatedness are when there is partiality of parental investment in offspring (as is the case for placental mammals, where there is also the possibility of extended postnatal care by one parent), and in social groups where there is a sex-biased dispersal. From this evolutionary starting point, it is predicted that, at the behavioural level, imprinted genes will influence what can broadly be termed bonding and social behaviour. We examine the animal and human literature for examples of imprinted genes mediating these behaviours, and divide them into two general classes. Firstly, mother-offspring interactions (suckling, attachment and maternal behaviours) that are predicted to occur when partiality in parental investment in early postnatal offspring occurs; and secondly, adult social interactions, when there is an asymmetry of relatedness in social groups. Finally, we return to the evolutionary theory and examine whether there is a pattern of behavioural functions mediated by imprinted genes emerging from the limited data, and also whether any tangible predictions can be made with regards to the direction of action of genes of maternal or paternal origin.

  1. MOLECULAR IMPRINTED POLYMERS—Novel Polymer Adsorbents

    Institute of Scientific and Technical Information of China (English)

    LIHaitao; XUMancai; 等

    2001-01-01

    Molecular imprinted polymers(MIPs) are novel functional polymer materials and known as specific adsorbents for the template molecules,These novel functional polymers have promised potential applications in racemic resolution,sensor,chromatography,adsorptive separation and other fields.This review exhibits the approach for preparing MIPs,the features of MIPs obtained by different routes and the characteristics of adsorptive separations with MIPs.The molecular recognition mechanism and the idea of the present possibilities and limitations of molecular imprinting polymerization are discussed as well.

  2. Book Reviews

    Directory of Open Access Journals (Sweden)

    F.L. van Holthoon

    1970-01-01

    Full Text Available - Yvan Simonis, Bertel Nathhorst, Formal or structural studies of traditional tales. The usefulness of some methodological proposals advanced by Vladimir Propp, Alan Dundes, Claude Levi-Strauss and Edmund Leach. Acta Universitatis Stockholmiensis, Stockhlom Studies in Comparative Religion, 9 - Stockholm 1969. 80 p. bibliogr., index. - A.J.F. Köbben, G.P. Murdock, Ethnographic atlas. University of Pittsburgh Press, 1967. 128 pp. - J. Blauw, Banton Michael, Anthropological approaches to the study of religion. Tavistock Publications, London, 1966. XZII en 176p. - C. Baks, J.F. Boissevain, Netwerken en quasi-groepen; enkele beschouwingen over de plaats van de Niet-Groepen in de Sociale Wettenschappen. Oratie. Van Gorcum & Comp., Assen 1968. 44 pp. - C.J. Lammers, Tom Burns, Industrial man. Penguin Modern Sociology Readings. Harmondsworth, Middlesex: Penguin Books Ltd. 1969. 414 pp. - P. van Daalen, M.M. Albinski, Maatschappelijke behoefte aan sociologen. Rede Katholieke Universiteit te Nijmegen. Van Gorcum, Assen 1969. 37 blz. - W. Brand, Louise B. Young, Population in perspective. Oxford University Press, New York/London/Toronto, 1968. 460 blz. - J.H.B. den Ouden, C. Baks, Afschaffing van Pacht. Een onderzoek naar de sociale gevolgen van de afschaffing van pacht in twee dorpen van Zuid-Gujerat, India. Publikatie no. 13. Afdeling Zuid- en Zuidoost-Azië. Antropologisch-Sociologisch Centrum. Universiteit van Amsterdam. 1969. 228 pp. - Mohan K. Gautam, William H. Newell, A study of Gaddi scheduled tribe - and affiliated castes. Census of India 1961. Vol. XX, Part V-B. Himachal Pradesh. Report on scheduled castes and scheduled tribes. Government of India Press, Simla. 1967. I-IV plus 104 pp. with 14 black and white illustrations, appendices and bibliography. - P.J. van Winter, Monica Wilson, The Oxford history of South Africa. Vol. I, South Africa to 1870. Clarendon Press, Oxford 1969. XXXIII, 502 p., Leonard Thompson (eds. - Jan Knappert, Hasani bin

  3. Book Reviews

    Directory of Open Access Journals (Sweden)

    Ger P. Reesink

    1995-07-01

    Full Text Available - Rogier Busser, Peter Post, Japanse bedrijvigheid in Indonesië, 1868-1942; Structurele elementen van Japan’s vooroorlogse economische expansie in Zuidoost Azië. Proefschrift Vrije Universiteit, Amsterdam, 1991, xviii + 374 pp. - H.J.M. Claessen, Arne Aleksej Perminow, The long way home; Dilemmas of everyday life in a Tongan village. Oslo: Scandinavian University Press, 1993, 166 pp. - Aone van Engelenhoven, René van den Berg, Studies in Sulawesi linguistics III. Jakarta: Badan Penyelenggara Seri Nusa, Universitas Katolik Indonesia Atma Jaya, 1994, xii + 116 pp. [NUSA, Linguistic Studies of Indonesian and Other Languages in Indonesia 36.] - Will Derks, Wolfgang Marschall, Texts from the Islands; Oral and written traditions of Indonesia and the Malay world, (Procedings of the 7th European Colloquium on Indonesia and Malay Studies, Berne, June 1989 1994, iii + 411 pp. [Ethnologica Bernensia 4]. - Michael Kaden, Krishna Sen, Indonesian Cinema; Framing the New Order, London: Zed Books, 1994, x + 188 pp. - Nico Kaptein, Mona Abaza, Indonesian Students in Cairo; Islamic education perceptions and exchanges, Paris: Association Archipel, 1994, 198 pp. [Cahier d’Archipel 23.] - P. Keppy, Chris Manning, Indonesia assessment 1993; Labour: Sharing in the benefits of growth? Canberra: Australian National University, 1993, xxi + 326 pp., Joan Hardjono (eds. - Anke Niehof, Jan-Paul Dirkse, Development and social welfare; Indonesia’s experiences under the New Order, Leiden: KITLV Press, 1993, xi + 295 pp., Frans Hüsken, Mario Rutten (eds. - Hetty Nooy-Palm, Michale C. Howard, Textiles of Southeast Asia; An annotated and illustrated bibliography. Bangkok: White Lotus, 1994, 212 pp. + 64 pp. pf photographs in colour. - Harry A. Poeze, Hans van Miert, Een koel hoofd en een warm hart; Nationalisme, Javanisme en jeugdbeweging in Nederlands-Indië, 1918-1930. Amsterdam: De Bataafsche Leeuw, 1995, 424 pp. - Ger P. Reesink, Jürg Wassmann, Historical atlas of

  4. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-10-01

    : KITLV Press, 2002, viii + 246 pp. [Proceedings 5.], Nico Kaptein (eds -Anton Ploeg, William C. Clarke, Remembering Papua New Guinea; An eccentric ethnography. Canberra: Pandanus Books, Research School of Pacific and Asian Studies, Australian National University, 2003, 178 pp. -Nathan Porath, Gerco Kroes, Same hair, different hearts; Semai identity in a Malay context; An analysis of ideas and practices concerning health and illness. Leiden: Research School of Asian, African and Amerindian Studies (CNWS, Universiteit Leiden, 2002, 188 pp. -Guido Sprenger, Grant Evans, Laos; Culture and society. Chiang Mai: Silkworm Books, 1999, xi + 313 pp. -Gerard Termorshuizen, Dik van der Meulen, Multatuli; Leven en werk van Eduard Douwes Dekker. Nijmegen: SUN, 2002, 912 pp. -Paige West, Karl Benediktsson, Harvesting development; The construction of fresh food markets in Papua New Guinea. Copenhagen: Nordic Institute of Asian Studies/Ann Arbor: University of Michigan Press, 2002, xii + 308 pp. -Edwin Wieringa, Amirul Hadi, Islam and state in Sumatra; A study of seventeenth-century Aceh. Leiden: Brill, 2004, xiii + 273 pp. [Islamic History and Civilization, 48.] -Robin Wilson, Pamela J. Stewart ,Remaking the world; Myth, mining and ritual change among the Duna of Papua New Guinea. Washington: Smithsonian Institution Press, 2002, xvi + 219 pp. [Smithsonian Series in Ethnographic Enquiry.], Andrew Strathern (eds

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2002-01-01

    Full Text Available -Stephen J. Appold, Heidi Dahles ,Tourism and small entrepreneurs; Development, national policy, and entrepreneurial culture: Indonesian cases. Elmsford, New York: Cognizant Communication Corporation, 1999, vi + 165 pp., Karin Bras (eds -Jean-Pascal Bassino, Peter Boothroyd ,Socioeconomic renovation in Vietnam; The origin, evolution and impact of Doi Moi. Singapore: Institute of Southeast Asian Studies, 2001, xv + 175 pp., Pham Xuan Nam (eds -Peter Boomgaard, Patrick Vinton Kirch, The wet and the dry; Irrigation and agricultural intensification in Polynesia. Chicago: The University of Chicago Press, 1994, xxii + 385 pp. -A.Th. Boone, Chr.G.F. de Jong, De Gereformeerde Zending in Midden-Java 1931-1975; Een bronnenpublicatie. Zoetermeer: Boekencentrum, 1997, xxiv + 890 pp. [Uitgaven van de Werkgroep voor de Geschiedenis van de Nederlandse Zending en Overzeese Kerken, Grote Reeks 6.] -Okke Braadbaart, Colin Barlow, Institutions and economic change in Southeast Asia; The context of development from the 1960s to the 1990s. Cheltenham: Edward Elgar, xi + 204 pp. -Freek Colombijn, Abidin Kusno, Behind the postcolonial; Architecture, urban space, and political cultures in Indonesia. London: Routledge, 2000, xiv + 250 pp. -Raymond Corbey, Michael O'Hanlon ,Hunting the gatherers; Ethnographic collectors, agents and agency in Melanesia, 1870s -1930s. Oxford: Bergahn Books, 2000, xviii + 286 pp. [Methodology and History in Anthropology 6.], Robert L. Welsch (eds -Olga Deshpande, Hans Penth, A brief histroy of Lan Na; Civilizations of North Thailand. Chiang Mai: Silkworm Books, 2000, v + 74 pp. -Aone van Engelenhoven, I Ketut Artawa, Ergativity and Balinese syntax. Jakarta: Badan Penyelenggaran Seri NUSA, Universitas Katolik Indonesia Atma Jaya, 1998, v + 169 pp (in 3 volumes. [NUSA Linguistic Studies of Indonesian and Other Languages in Indonesia 42, 43, 44.] -Rens Heringa, Jill Forshee, Between the folds; Stories of cloth, lives, and travels from Sumba

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    Brian Swann

    1983-10-01

    Full Text Available - G.J. Abbink, J.M. Schoffeleers, Missie en Ontwikkeling in Oost-Afrika. Een ontmoeting van culturen, Nijmegen-Baarn: Katholiek Studiecentrum - Ambo, 1983, 167 pp., H. Obdeijn (eds. - Gary Brana-Shute, Barry B. Levine, Benjy Lopez: A picaresque tale of emigration and return. Basic Books, 1980. 240 pages, bibliography, no index. - Victoria M. Clara van Groenendael, Günter Spitzing, Das indonesische Schattenspiel Bali - Java - Lombok, Köln: Dumont, 1981, 236 pages, photographs, illustrations, map, tables, glossary, bibliography, index. Dumont-Taschenbücher 110. - Dirk van Dusseldorp, B. Galjart, Participation of the poor in development. Contributions to a seminar. 325 pp. Leiden development studies 2, Institute of cultural and social studies, University of Leiden, Leiden 1982., D. Buys (eds. - C. van Dijk, R. de Bruin, Islam en nationalisme in door Japan bezet Indonesië: 1942-1945, ‘s-Gravenhage: Staatsuitgeverij, 1982. Rijksinstituut voor Oorlogsdocumentatie, Cahiers over Nederland en de Tweede Wereldoorlog, nr. 3. - R. Hagesteijn, H.B. Sarkar, Literary heritage of Southeast Asia. Calcutta, Firma KLM Private Limited, 265 pages. - M. Hekker, S. Price, Afro-American arts of the Suriname rain forest. University of California Press, Berkeley/Los Angelos/London, 1981. 237 pp. Maps, Ill., R. Price (eds. - M. Hekker, S.R. Siregar, Adat, Islam and Christianity in a Batak Homeland. Athens, Ohio 1981. Papers in International studies, Southeast Asia series no. 57, Ohio University. 108 pp. - P.E. de Josselin de Jong, Wazir-Jahan Begum Karim, Ma’ Betisék concepts of living things, 1981. New Jersey: Athlone Press. London school of economics monographs on social anthropology no. 54. xv, 270 pp., 3 maps, 6 figs., 11 tables. - Peter Kloos, Paul Alexander, Sri Lanka Fishermen. Rural capitalism and peasant society. Canberra, Australian National University Monographs no. 7, 1982, 328 pp. - Peter Kloos, James Brow, Vedda villages of Anuradhapura. The

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    R.A. Römer

    1963-10-01

    Full Text Available - A.J.C. Lach de Bére, Fernand van Langenhove, Consciences Tribales et Nationales en Afrique Noire. Institut Royal des Relations Internationales, Bruxelles. Martinus Nijhoff, ‘s-Gravenhage, 1960; 444 blz. - J.H. Scherer, A.H.J. Prins, The Swahili-speaking peoples of Zanzibar and the E. African Coast (Arabs, Shirazi and Swahili. Ethnographic Survey of Africa: East Central Africa, part XII. Uitgave van het International African Institute, London, 1961. 143 pp., m. kaart. - P. Driessens, Carol Brubaker, Geesten van het woud. Servire Luxe Pockets nr. 66. Servire, Den Haag 1963. 175 pp., 24 foto’s. - Joh. J. Hanrath, Indonesian Economics. The concept of dualism in theory and policy. Den Haag (W. van Hoeve 1961. 443 pp. - W. Ph. Coolhaas, H.R.C. Wright, East-Indian economic problems of the age of Cornwallis and Raffles. Luzac, London, 1961; 271 pp. - H.J. de Graaf, M.A.P. Meilink-Roelofsz, Asian trade and European influence in the Indonesian Archipelago between 1500 and about 1630. Academisch Proefschrift Amsterdam (S.U.. M. Nijhoff, ‘s-Gravenhage 1962. 471 pp. - Logemann, Herbert Feith, The decline of constitutional democracy in Indonesia. Cornell University Press, Ithaca, New York, 1962. XX en 608 blz. - F.D.K. Bosch, G. Coedés, Les peuples de la péninsule indochinoise. 228 pp., 16 pl., 1 carte; Ed. Dunod, Paris, 1962. - L. Sluimers, Sirdar Ikbal Ali Shah, Viet-nam. London, Octagon Press, 1960. XV, 232 blz., krt. - L. Sluimers, J.G. Keyes, A bibliography of North Vietnamese Publications in the Cornell University Library. Ithaca, Cornell University, 1962. Data paper: Number 47. Southeast Asia Program. Department of Asian Studies. Cornell University. X, 116 blz., X. - A.F.P. Hulsewé, G.P. Oery, The Man-Shu (Book of the Southern Barbarians, translated by Gordon H. Luce, edited by G.P. Oery; Data Paper Nr. 44, Southeast Asia Program, Dept. of Far Eastern Studies, Cornell Univ., Ithaca, N.Y.; 1961. (X + 116 pp., 1 map. - C.H.M. Palm, Felix M

  8. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-01-01

    Jeroen Kemperman. Leiden: KITLV Press, 2002, 570 pp. [Verhandelingen 206.] -Gerry van Klinken, Grayson Lloyd ,Indonesia today; Challenges of history. Singapore: Institute of Southeast Asian studies, 2001, 359 pp., Shannon Smith (eds -Johanna van Reenen, Frédéric Durand, Timor Lorosa'e, pays au carrefour de l'Asie et du Pacifique; Un atlas géo-historique. Marne-la-Vallée: Presses Universitaires de Marne-la-Vallée, 2002, 208 pp. -William R. Roff, Mona Abaza, Debates on Islam and knowledge in Malaysia and Egypt; Shifting worlds. London: RoutledgeCurzon, 2002, xix + 304 pp. -Mariëtte van Selm, Chr. van Fraassen ,G.E. Rumphius, De Ambonse eilanden onder de VOC, zoals opgetekend in 'De Ambonse landbeschrijving'. Utrecht: Landelijk Steunpunt Educatie Molukkers, 2002, 254 pp., H. Straver (eds -K. Thirumaran, Prema-Chandra Athukorala, Crisis and recovery in Malaysia; The role of capital controls. Cheltenham: Elgar, 2001, xii + 159 pp. -K. Thirumaran, John Hilley, Malaysia; Mahathirism, hegemony and the new opposition. London: Zed books, 2001, xiii + 305 pp. -Reina van der Wiel, Damien Kingsbury ,Foreign devils and other journalists. Clayton VIC: Monash Asia Institute, 2000, vi + 277 pp. [Monash papers on Southeast Asia 52.], Eric Loo, Patricia Payne (eds -Jennifer Fraser, Philip Yampolsky, Music of Indonesia. Washington DC: Smithsonian Folkways recordings, 1991-2000, 20 compact discs plus a CD of selections from the series, Discover Indonesia. All with accompanying booklets. -Robert Wessing, Nicola Tannenbaum ,Founders' cults in Southeast Asia; Ancestors, polity, and identity. New Haven CT: Yale University Southeast Asian studies, 2003, xi + 373 pp. [Yale Southeast Asia studies Monograph 52.], Cornelia Ann Kammerer (eds -Robert Wessing, Henri Chambert-Loir ,The potent dead; Ancestors, saints and heroes in contemporary Indonesia. Crows Nest, New South Wales: Allen and Unwin, Honolulu: University of Hawai'i Press, 2002, xxvi + 243 pp. [Southeast Asia publications series

  9. Book Reviews

    Directory of Open Access Journals (Sweden)

    Danker H. Schaareman

    1980-01-01

    Full Text Available - H.J.M. Claessen, Jan van Bremen, Symposion. Tijdschrift voor Maatschappijwetenschap. Onder redactie van Jan van Bremen, Cees Cruson, Helle Snel, Jojada Verrips, Willem Wolters en Ton Zwaan. Uitgave: Stichting voor Maatschappijwetenschappelijk Onderzoek., Cees Cruson, Helle Snel (eds. - H.J.M. Claessen, Neil Lifuka, Logs in the current of the sea. Neil Lifuka’s story of Kioa and the Vaitupu colonists. Edited and introduced by Klaus-Friedrich Koch. With a foreword by Professor H.E. Maude. Cambridge, Mass.: Langdon Associates Press. 1978. - H.J.M. Claessen, R.R. Nayacakalou, Leadership in Fiji. 1975. Melbourne etc.: Oxford University Press. 170 pp. Appendices, tables, notes. - H.J.M. Claessen, Michael W. Young, The ethnography of Malinowski; The Trobriand Islands 1915-1918. London: Routledge and Kegan Paul, 1979. Bibliography, Index, illustrations. - P.E. de Josselin de Jong, G.B. Milner, Natural symbols in South East Asia. School of Oriental and African Studies, London 1978. 181 p., 13 plates. - P. Kloos, G.N. Appell, Ethical dilemmas in anthropological inquiry: A case book, Waltham (Mass., Crossroads Press, 1978, xii + 291 pp. - David S. Moyer, M.B. Hooker, A concise legal history of South-East Asia. Oxford: Clarendon Press, 1978. 289 pp. - J.G. Oosten, Henri J.M. Claessen, The early state. Mouton Publishers. The Hague, The Netherlands 1978. XII + 690 pages., P. Skalník (eds. - J.G. Oosten, Jean Poirier, Ethnologie Régionale 2. Asie-Amérique-Mascareignes. Sous la direction de Jean Poirier. Encyclopédie de la Pleiade. Gallimard, Paris 1978. - J.G. Oosten, A. de Ruyter, Een speurtocht naar het denken. Een inleiding tot het structuralisme van Claude Lévi Strauss. Van Gorcum & Comp. N.V., Assen 1979. Serie: Terreinverkenningen in de Culturele Anthropologie, nr. 16. - Anton Ploeg, Raymond C. Kelly, Etoro Social Structure. A study in structural contradiction. Foreword by Marshall Sahlins. The University of Michigan Press. Ann Arbor, 1974, 1977

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2005-01-01

    Full Text Available -Monika Arnez, Niels Mulder, Southeast Asian images; Towards civil society? Chiang Mai: Silkworm Books, 2003, ix + 253 pp. -Adriaan Bedner, Connie Carter, Eyes on the prize; Law and economic development in Singapore. The Hague: Kluwer Law International, xviii + 307 pp. [The London-Leiden series on law, administration and development 7.] -Amrit Gomperts, J.R. van Diessen ,Grote atlas van Nederlands Oost-Indië/Comprehensive atlas of the Netherlands East Indies. Zierikzee: Asia Maior, Utrecht: Koninklijk Nederlands Aardrijkskundig Genootschap (KNAG, 2004, 480 pp. (editors, with the collaboration of R.C.M. Braam, W. Leijnse, P.A. Levi, J.J. Reijnders, R.P.G.A. Voskuil and M.P.B. Ziellemans, F.J. Ormeling (eds -Stuart R. Harrop, Adriaan Bedner ,Towards integrated environmental law in Indonesia? Leiden: Research school CNWS, School of Asian, African and Amerindian studies, 2003, 161 pp. [CNWS publications 127.], Nicole Niessen (eds -David Henley, Paul H. Kratoska ,Locating Southeast Asia: Geographies of knowledge and politics of space. Singapore: Singapore University Press, 2005, xi + 326 pp., Remco Raben, Henk Schulte Nordholt (eds -Gerry van Klinken, Anthony J. Langlois, The politics of justice and human rights; Southeast Asia and universalist theory. Cambridge: Cambridge University Press, 2001, xi + 214 pp. [Cambridge Asia-Pacific studies.] -Koh Keng We, Jurrien van Goor, Prelude to colonialism; The Dutch in Asia. Hilversum: Verloren, 2004, 127 pp. -Lim Beng Soon, Thomas H. Slone, Prokem; An analysis of a Jakartan slang. Oakland: Masalai Press, 2003, 95 pp. -Lim Beng Soon, Neil Khor Jin Keong ,The Penang Po Leung Kuk; Chinese women, prostitution and a welfare organisation. Kuala Lumpur; The Malaysian branch of the Royal Asiatic society (MBRAS, 2004, VII + 181 pp., Khoo Keat Siew (eds -Dick van der Meij, J. Thomas Lindblad ,Macht en majesteit; Opstellen voor Cees Fasseur bij zijn afscheid als hoogleraar in de geschiedenis van Indonesië aan de

  11. Genomic imprinting and genetic effects on muscle traits in mice

    Directory of Open Access Journals (Sweden)

    Kärst Stefan

    2012-08-01

    Full Text Available Abstract Background Genomic imprinting refers to parent-of-origin dependent gene expression caused by differential DNA methylation of the paternally and maternally derived alleles. Imprinting is increasingly recognized as an important source of variation in complex traits, however, its role in explaining variation in muscle and physiological traits, especially those of commercial value, is largely unknown compared with genetic effects. Results We investigated both genetic and genomic imprinting effects on key muscle traits in mice from the Berlin Muscle Mouse population, a key model system to study muscle traits. Using a genome scan, we first identified loci with either imprinting or genetic effects on phenotypic variation. Next, we established the proportion of phenotypic variation explained by additive, dominance and imprinted QTL and characterized the patterns of effects. In total, we identified nine QTL, two of which show large imprinting effects on glycogen content and potential, and body weight. Surprisingly, all imprinting patterns were of the bipolar type, in which the two heterozygotes are different from each other but the homozygotes are not. Most QTL had pleiotropic effects and explained up to 40% of phenotypic variance, with individual imprinted loci accounting for 4-5% of variation alone. Conclusion Surprisingly, variation in glycogen content and potential was only modulated by imprinting effects. Further, in contrast to general assumptions, our results show that genomic imprinting can impact physiological traits measured at adult stages and that the expression does not have to follow the patterns of paternal or maternal expression commonly ascribed to imprinting effects.

  12. Cataloging Pirated Chinese Books

    Science.gov (United States)

    Wang, Sze-Tseng

    1971-01-01

    Various types of pirated Chinese books are given with specific examples. The basic steps followed for the proper identification of these books is described, and remedies suggested in case the original is discovered after the book has been cataloged according to the information given by the book pirate. (13 references) (Author/NH)

  13. Atomic-Scale Imprinting into Amorphous Metals

    Science.gov (United States)

    Schwarz, Udo; Li, Rui; Simon, Georg; Kinser, Emely; Liu, Ze; Chen, Zheng; Zhou, Chao; Singer, Jonathan; Osuji, Chinedum; Schroers, Jan

    Nanoimprinting by thermoplastic forming (TPF) has attracted significant attention in recent years due to its promise of low-cost fabrication of nanostructured devices. Usually performed using polymers, amorphous metals have been identified as a material class that might be even better suited for nanoimprinting due to a combination of mechanical properties and processing ability. Commonly referred to as metallic glasses, their featureless atomic structure suggests that there may not be an intrinsic size limit to the material's ability to replicate a mold. To study this hypothesis, we demonstrate atomic-scale imprinting into amorphous metals by TPF under ambient conditions. Atomic step edges of a SrTiO3 (STO) single crystal used as mold were successfully imprinted into Pt-based bulk metallic glasses (BMGs) with high fidelity. Terraces on the BMG replicas possess atomic smoothness with sub-Angstrom roughness that is identical to the one measured on the STO mold. Systematic studies revealed that the quality of the replica depends on the loading rate during imprinting, that the same mold can be used multiple times without degradation of mold or replicas, and that the atomic-scale features on as-imprinted BMG surfaces has impressive long-term stability (months).

  14. High Sensitivity Imprint Measurements on Nike Laser

    Science.gov (United States)

    Karasik, Max

    2005-10-01

    Hydrodynamic instability seeded by laser non-uniformity (laser imprint) is an important factor in performance of direct-drive ICF targets. Most of the imprint occurs during the initial low-intensity (``foot'') part of the pulse, necessary to compress the target to achieve high gain. Experiments are carried out on Nike KrF laser with induced spatial incoherence (ISI) smoothing. The amount of imprint is varied by changing the uniformity the foot of the pulse. The resulting Raleigh-Taylor (RT) amplified areal mass non-uniformity is measured by face-on x-ray radiography using Bragg reflection from a curved crystal coupled to an x-ray streak camera. The streak camera was recently retrofitted with a new high sensitivity CCD camera. The sensitivity of the CCD has enabled it to be fiberoptically coupled directly to the streak camera output, without an image intensifier and lens coupling. This gave an increased overall spatial resolution as well as lower noise. Because of the strong short wavelength component of RT amplified imprint, the increased resolution and lower noise resulted in much lower noise floor in the measurement. Experimental results are compared with 2D simulations using FAST hydrocode for a range of foot uniformities and intensities. Work supported by the U. S. DOE/NNSA.

  15. Books Are Good Friends

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Books are our friends because they are bridges to knowledge.Knowledge is valuable because it enriches our life and brings us happiness.Almost all great men in the history of mankind loved books.We have every reason to believe it is the knowledge in books that led them to success.There is no genius without books.Because books give them knowledge and knowledge gives them

  16. Book Reviews

    Directory of Open Access Journals (Sweden)

    J. Bastin

    1982-04-01

    . - F.G.P. Jaquet, H.J. de Graaf, Wonderlijke verhalen uit de Indische historie, ‘s-Gravenhage, Moesson 1981. 173 pp. Ills. - F.G.P. Jaquet, J. Landwehr, De Nederlander uit en thuis; spiegel van het dagelijks leven uit bijzondere zeventiende-eeuwse boeken. Alphen aan den Rijn, Sijthoff, 1981. 200 pp. Ills. - P.E. de Josselin de Jong, Michael G. Peletz, Social history and evolution in the interrelationship of adat and Islam in Rembau, Negeri Sembilan, Research Notes and Discussions Paper no. 27, Institute of Southeast Asian Studies, Singapore 1981. 59 pages. - P.E. de Josselin de Jong, Anthony Reid, Perceptions of the past in Southeast Asia, Heinemann Educational Books for Asian Studies Asociation of Australia, Singapore 1979. 436 pp. Bibliographical Appendix, Index, 3 maps., David Marr (eds. - J.E. van Lohuizen-de Leeuw, J. Bastin, Prints of Southeast Asia in the India Office Library - The East India Company in Malaysia and Indonesia 1786-1824, Her Majesty’s Stationery Office, London, 1979, XIII + 228 pp. including 98 pls., frontispiece in colour., P. Rohatgi (eds. - Anke Niehof, Victor T. King, Essays on Borneo Society, Hull Monographs on South-East Asia 7, Oxford University Press, 1978, 256 pp. - C.H.M. Nooy-Palm, Renato Rosaldo, Ilongot headhunting 1883-1974, a study in society and history. Stanford University Press, Stanford, California, 1980. 313 pp., maps, photographs and diagrams. Chronological and general index. - Els Postel-Coster, Clio Presvelou, The household, women and agricultural development, Proceedings of a symposium organised by the Department of Home Economics, Agricultural University, Wageningen, Miscellaneous Papers 17, 1980, Landbouwhogeschool Wageningen, The Netherlands., Saskia Spijkers-Zwart (eds. - G.J. van Reenen, Claudine Salmon, Les Chinois de Jakarta; Temples et vie collective [The Chinese of Jakarta; Temples and communal life], Etudes insulindiennes - Archipel 1, Association Archipel, Paris, 1980 (deuxième impression, xxviii + 358 pp

  17. Book Review:

    Science.gov (United States)

    Sanders, J. H.

    1984-01-01

    The NATO Advanced Study Institute held at Erice, Sicily, in November 1981 brought together specialists in precise measurement to present a tutorial introduction to quantum metrology and the measurement of the fundamental physical constants. Ever since the evolution of experimental physics as a scientific pursuit the measurement of the values of quantities accepted to be constants of nature has commanded the attention of some of the world's most accomplished workers in this field. Their efforts to seek out the sources of systematic error and to reduce the random errors have produced significant advances in techniques and a continual interest in their results from users and critics: as Raymond T Birge, who pioneered the evaluation of the 'best' values of the constants from the available measurements, observed (perhaps with tongue-in-cheek) "it is the continual variation in the values of these quantities that furnishes most of the interest in the subject". Long before the recognition of the fundamental constants the measurement of mass, length and time grew as a matter of necessity in organized communities, especially in agriculture, commerce and navigation. The adoption of standards, first local, then national, and now international, was a natural consequence. It is particularly relevant that the published proceedings of the NATO school opens with a historical survey by Pierre Giacomo of the Bureau International des Poids et Mesures, which places the subsequent papers in perspective. Measurements which realize the standards of length and time, and those from which values of the fundamental constants are derived, are of such a nature that a considerable background knowledge of physics is needed for their understanding. (The principle of the caesium frequency standard and the physics of the Josephson junction are a long haul from Michelson's measurement of the speed of light and the Millikan oil drop experiment familiar in the school books.) With this in mind, George

  18. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1994-07-01

    Full Text Available -Peter Hulme, Stephen Greenblatt, New World Encounters. Berkeley: University of California Press, 1993. xviii + 344 pp. -Nigel Rigby, Alan Riach ,The radical imagination: Lectures and talks by Wilson Harris. Liège: Department of English, University of Liège, xx + 126 pp., Mark Williams (eds -Jonathan White, Rei Terada, Derek Walcott's poetry: American Mimicry. Boston: North-eastern University Press, 1992. ix + 260 pp. -Ray A. Kea, John Thornton, Africa and Africans in the making of the Atlantic world, 1400-1680. Cambridge: Cambridge University Press, 1992. xxxviii + 309 pp. -B.W. Higman, Barbara L. Solow, Slavery and the rise of the Atlantic system. Cambridge: Cambridge University Press, 1991. viii + 355 pp. -Sidney W. Mintz, Michael Mullin, Africa in America: Slave acculturation and resistance in the American South and the British Caribbean, 1736-1831. Urbana: University of Illinois Press. 412 pp. -Karen Fog Olwig, Corinna Raddatz, Afrika in Amerika. Hamburg: Hamburgisches Museum für Völkerkunde, 1992. 264 pp. -Lee Haring, William Bascom, African folktales in the new world. Bloomington: Indiana University Press, 1992. xxv + 243 pp. -Frank Jan van Dijk, Dale A. Bisnauth, History of religions in the Caribbean. Kingston: Kingston Publishers, 1989. 225 pp. -Gloria Wekker, Philomena Essed, Everyday racism: Reports from women of two cultures. Alameda CA: Hunter House, 1990. xiii + 288 pp.''Understanding everyday racism: An interdisciplinary theory. Newbury Park CA: Sage, 1991. x + 322 pp. -Deborah S. Rubin, Vron Ware, Beyond the Pale: White women, racism, and history. London: Verso, 1992. xviii + 263 pp. -Michael Hanchard, Peter Wade, Blackness and race mixture: The dynamics of racial identity in Colombia. Baltimore: John Hopkins University Press, 1993. xv + 415 pp. -Rosalie Schwartz, Louis A. Pérez, Jr., Slaves, sugar, & colonial society: Travel accounts of Cuba, 1801-1899. Wilmington DE: SR Books, 1992. xxvi + 259 pp. -Susan Eckstein, Sandor

  19. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-07-01

    Full Text Available -Bill Maurer, Mimi Sheller, Consuming the Caribbean: From Arawaks to Zombies. New York: Routledge, 2003. ix + 252 pp. -Norman E. Whitten, Jr., Richard Price ,The root of roots: Or, how Afro-American anthropology got its start. Chicago: Prickly Paradigm Press/University of Chicago Press, 2003. 91 pp., Sally Price (eds -Holly Snyder, Paolo Bernardini ,The Jews and the expansion of Europe to the West, 1450-1800. New York: Berghahn Books, 2001. xv + 567 pp., Norman Fiering (eds -Bridget Brereton, Seymour Drescher, The mighty experiment: Free labor versus slavery in British emancipation. New York: Oxford University Press, 2002. 307 pp. -Jean Besson, Kathleen E.A. Monteith ,Jamaica in slavery and freedom: History, heritage and culture. Kingston; University of the West Indies Press, 2002. xx + 391 pp., Glen Richards (eds -Michaeline A. Crichlow, Jean Besson, Martha Brae's two histories: European expansion and Caribbean culture-building in Jamaica. Chapel Hill: University of North Carolina Press, 2002. xxxi + 393 pp. -Christopher Schmidt-Nowara, Joseph C. Dorsey, Slave traffic in the age of abolition: Puerto Rico, West Africa, and the Non-Hispanic Caribbean, 1815-1859. Gainesville: University Press of Florida, 2003. xvii + 311 pp. -Arnold R. Highfield, Erik Gobel, A guide to sources for the history of the Danish West Indies (U.S. Virgin Islands, 1671-1917. Denmark: University Press of Southern Denmark, 2002. 350 pp. -Sue Peabody, David Patrick Geggus, Haitian revolutionary studies. Bloomington: Indiana University Press, 2002. xii + 334 pp. -Gerdès Fleurant, Elizabeth McAlister, Rara! Vodou, power, and performance in Haiti and its Diaspora. Berkeley: University of California Press, 2002. xviii + 259 pp. and CD demo. -Michiel Baud, Ernesto Sagás ,The Dominican people: A documentary history. Princeton NJ: Marcus Wiener, 2003. xiii + 278 pp., Orlando Inoa (eds -Samuel Martínez, Richard Lee Turits, Foundations of despotism: Peasants, the Trujillo regime

  20. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1996-07-01

    . xiv + 217 pp., Lou Anne Barclay (eds -Catherine Levesque, Allison Blakely, Blacks in the Dutch world: The evolution of racial imagery in a modern society. Bloomington: Indiana University Press, 1993. xix + 327 pp. -Dennis J. Gayle, Frank Fonda Taylor, 'To hell with paradise': A history of the Jamaican tourist industry. Pittsburgh: University of Pittsburgh Press, 1993. ix + 239 pp. -John P. Homiak, Frank Jan van Dijk, Jahmaica: Rastafari and Jamaican society, 1930-1990. Utrecht: ISOR, 1993. 483 pp. -Peter Mason, Arthur MacGregor, Sir Hans Sloane: Collector, scientist, antiquary, founding Father of the British Museum. London: British Museum Press, 1994. -Philip Morgan, James Walvin, The life and times of Henry Clarke of Jamaica, 1828-1907. London: Frank Cass, 1994. xvi + 155 pp. -Werner Zips, E. Kofi Agorsah, Maroon heritage: Archaeological, ethnographic and historical perspectives. Kingston: Canoe Press, 1994. xx + 210 pp. -Michael Hoenisch, Werner Zips, Schwarze Rebellen: Afrikanisch-karibischer Freiheitskampf in Jamaica. Vienna Promedia, 1993. 301 pp. -Elizabeth McAlister, Paul Farmer, The uses of Haiti. Monroe ME: Common Courage Press, 1994. 432 pp. -Robert Lawless, James Ridgeway, The Haiti files: Decoding the crisis. Washington DC: Essential Books, 1994. 243 pp. -Bernadette Cailler, Michael Dash, Edouard Glissant. Cambridge: Cambridge University Press, 1995. xii + 202 pp. -Peter Hulme, Veronica Marie Gregg, Jean Rhys's historical imagination: Reading and writing the Creole. Chapel Hill: University of North Carolina Press, 1995. xi + 228 pp. -Silvia Kouwenberg, Francis Byrne ,Focus and grammatical relations in Creole languages. Amsterdam/Philadelphia: John Benjamins, 1993. xvi + 329 pp., Donald Winford (eds -John H. McWhorter, Ingo Plag, Sentential complementation in Sranan: On the formation of an English-based Creole language. Tübingen: Max Niemeyer, 1993. ix + 174 pp. -Percy C. Hintzen, Madan M. Gopal, Politics, race, and youth in Guyana. San Francisco: Mellen

  1. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1993-07-01

    Full Text Available -Gesa Mackenthun, Stephen Greenblatt, Marvelous Possessions: The wonder of the New World. Chicago: University of Chicago Press, 1991. ix + 202 pp. -Peter Redfield, Peter Hulme ,Wild majesty: Encounters with Caribs from Columbus to the present day. An Anthology. Oxford: Oxford University Press, 1992. x + 369 pp., Neil L. Whitehead (eds -Michel R. Doortmont, Philip D. Curtin, The rise and fall of the plantation complex: Essays in Atlantic history. New York: Cambridge University Press, 1990. xi + 222 pp. -Roderick A. McDonald, Hilary McD.Beckles, A history of Barbados: From Amerindian settlement to nation-state. Cambridge: Cambridge University Press, 1990. xv + 224 pp. -Gertrude J. Fraser, Hilary McD.Beckles, Natural rebels; A social history of enslaved black women in Barbados. New Brunswick NJ and London: Rutgers University Press and Zed Books, 1990 and 1989. ix + 197 pp. -Bridget Brereton, Thomas C. Holt, The problem of freedom: Race, labor, and politics in Jamaica and Britain, 1832-1938. Baltimore: John Hopkins University Press, 1991. xxxi + 517 pp. -Peter C. Emmer, A. Meredith John, The plantation slaves of Trinidad, 1783-1816: A mathematical and demographic inquiry. Cambridge: Cambridge University Press, 1988. xvi + 259 pp. -Richard Price, Robert Cohen, Jews in another environment: Surinam in the second half of the eighteenth century. Leiden: E.J. Brill, 1991. xv + 350 pp. -Russell R. Menard, Nigel Tattersfield, The forgotten trade: comprising the log of the Daniel and Henry of 1700 and accounts of the slave trade from the minor ports of England, 1698-1725. London: Jonathan Cape, 1991. ixx + 460 pp. -John D. Garrigus, James E. McClellan III, Colonialism and science: Saint Domingue in the old regime. Baltimore: John Hopkins University Press, 1992. xviii + 393 pp. -Lowell Gudmundson, Richard H. Collin, Theodore Roosevelt's Caribbean: The Panama canal, the Monroe doctrine, and the Latin American context. Baton Rouge: Louisiana State University

  2. Book Reviews

    Directory of Open Access Journals (Sweden)

    Joseph Aquilina

    1976-01-01

    .J. Zoetmulder, Himansu Bhusan Sarkar, Corpus of the inscriptions of Java (Corpus Inscriptionum Javanicorum (up to 928 A.D., K.L. Mukhopadhyay, Calcutta, 1972. Vol. I 314 pp., Vol. II 359 pp. - J.G. Oosten, Wilhelmina van Wetering, Hekserij bij de Djuka. Een sociologische benadering. Academisch proefschrift, gestencilde uitgave, 1973. - Willem F.L. Buschkens, Richard Price, Maroon societies, rebel slave communities in the Americas. Anchor Books, Anchor Press/Doubleday Garden City, New York 1973. 429 pag., 7 ill.

  3. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1993-01-01

    Full Text Available -Louis Allaire, Samuel M. Wilson, Hispaniola: Caribbean chiefdoms in the age of Columbus. Tuscaloosa: University of Alabama Press, 1990. xi + 170 pp. -Douglas Melvin Haynes, Philip D. Curtin, Death by migration: Europe's encounter with the tropical world in the nineteenth century. Cambridge: Cambridge University Press, 1989. xviii + 251 pp. -Dale Tomich, J.H. Galloway, The sugar cane industry: An historical geography from its origins to 1914. Cambridge: Cambridge University Press, 1989. xii + 266 pp. -Myriam Cottias, Dale Tomich, Slavery in the circuit of sugar: Martinique and the world economy, 1830 -1848. Baltimore: John Hopkins University Press, 1990. xiv + 352 pp. -Robert Forster, Pierre Dessalles, La vie d'un colon à la Martinique au XIXe siècle. Pré-senté par Henri de Frémont. Courbevoie: s.n., 1984-1988, four volumes, 1310 pp. -Hilary Beckles, Douglas V. Armstrong, The old village and the great house: An archaeological and historical examination of Drax Hall Plantation, St Ann's Bay, Jamaica. Chicago: University of Illinois Press, 1990. xiii + 393 pp. -John Stewart, John A. Lent, Caribbean popular culture. Bowling Green OH: Bowling Green State University Popular Press, 1990. 157 pp. -W. Marvin Will, Susanne Jonas ,Democracy in Latin America: Visions and realities. New York: Bergin & Garvey Publishers, 1990. viii + 224 pp., Nancy Stein (eds -Forrest D. Colburn, Kathy McAfee, Storm signals: Structural adjustment and development alternatives in the Caribbean. London: Zed books, 1991. xii + 259 pp. -Derwin S. Munroe, Peggy Antrobus ,In the shadows of the sun: Caribbean development alternatives and U.S. policy. Carmen Diana Deere (coordinator, Peter Phillips, Marcia Rivera & Helen Safa. Boulder CO: Westview Press, 1990. xvii + 246 pp., Lynne Bolles, Edwin Melendez (eds -William Roseberry, Louis A. Pérez, Jr., Lords of the mountain: Social banditry and peasant protest in Cuba, 1878-1918. Pittsburgh: University of Pittsburgh Press, 1989

  4. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2003-01-01

    Full Text Available -Timothy Barnard, J.M. Gullick, A history of Selangor (1766-1939. Kuala Lumpur: Malaysian branch of the Royal Asiatic Society, 1989, vi + 220 pp. [MBRAS Monograph 28.] -Okke Braadbaart, Michael L. Ross, Timber booms and institutional breakdown in Southeast Asia. Cambridge: Cambridge University Press, 2001, xvi + 237 pp. -H.J.M. Claessen, Patrick Vinton Kirch ,Hawaiki, ancestral Polynesia; An essay in historical anthropology. Cambridge: Cambridge University Press, 2001, xvii + 375 pp., Roger C. Green (eds -Harold Crouch, R.E. Elson, Suharto; A political biography. Cambridge: Cambridge University Press, 2001, xix + 389 pp. -Kees van Dijk, H.W. Arndt ,Southeast Asia's economic crisis; Origins, lessons, and the way forward. Singapore: Institute of Southeast Asian studies, 1999, ix + 182 pp., Hal Hill (eds -Kees van Dijk, Sebastiaan Pompe, De Indonesische algemene verkiezingen 1999. Leiden: KITLV Uitgeverij, 1999, 290 pp. -David van Duuren, Albert G. van Zonneveld, Traditional weapons of the Indonesian archipelago. Leiden: Zwartenkot art books, 2001, 160 pp. -Peter van Eeuwijk, Christian Ph. Josef Lehner, Die Heiler von Samoa. O Le Fofo; Monographie über die Heiler und die Naturheilmethoden in West-Samoa. Frankfurt am Main: Lang, 1999, 234 pp. [Mensch und Gesellschaft 4.] -Hans Hägerdal, Frans Hüsken ,Reading Asia; New research of Asian studies. Richmond: Curzon, 2001, xvi + 338 pp., Dick van der Meij (eds -Terence E. Hays, Jelle Miedema ,Perspectives on the Bird's head of Irian Jaya, Indonesia; Proceedings of the conference, Leiden, 13-17 October 1997. Amsterdam: Rodopi, 1998, xiii + 982 pp. (editors with the assistance of Connie Baak, Cecilia Odé, Rien A.C. Dam (eds -Menno Hekker, Peter Metcalf, They lie, we lie; Getting on with anthropology. London: Routledge, 2002, ix + 155 pp. -David Henley, Foong Kin, Social and behavioural aspects of malaria control; A study among the Murut of Sabah. Phillips, Maine: Borneo research council , 2000, xx

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Janet Rodenburg

    1992-04-01

    Full Text Available - Leonard Y. Andaya, H.A. Poeze, Excursies in Celebes; Een bundel bijdragen bij het afscheid van J. Noorduyn als directeur-secretaris van het Koninklijk Instituut voor Taal-, Land- en Volkenkunde. Leiden: KITLV Uitgeverij, 1991, 348 pp., P. Schoorl (eds. - Anne Booth, Adrian Clemens, Changing economy in Indonesia Volume 12b; Regional patterns in foreign trade 1911-40. Amsterdam: Royal Tropical Institute, 1992., J.Thomas Lindblad, Jeroen Touwen (eds. - A.P. Borsboom, James F. Weiner, The empty place; Poetry space, and being among the Foi of Papua New Guinea. Bloomington: Indiana University Press, 1991. - Martin van Bruinessen, Ozay Mehmet, Islamic identity and development; Studies of the Islamic periphery. London and New York: Routledge, 1990 (cheap paperback edition: Kula Lumpur: Forum, 1990, 259 pp. - H.J.M. Claessen, Timothy Earle, Chiefdoms: power, economy, and ideology. A school of American research book. Cambridge: Cambridge University Press, 1991. 341 pp., bibliography, maps, figs. - H.J.M. Claessen, Henk Schulte Nordholt, State, village, and ritual in Bali; A historical perspective. (Comparitive Asian studies 7. Amsterdam: VU University press for the centre for Asian studies Amsterdam, 1991. 50 pp. - B. Dahm, Ruby R. Paredes, Philippine colonial democracy. (Monograph series 32/Yale University Southeast Asia studies. New Haven: Yale Center for international and Asia studies, 1988, 166 pp. - Eve Danziger, Bambi B. Schieffelin, The give and take of everyday life; Language socialization of Kaluli children. (Studies in the social and cultural foundations of language 9. Cambridge: Cambridge University Press, 1991. - Roy Ellen, David Hicks, Kinship and religion in Eastern Indonesia. (Gothenburg studies in social anthropology 12. Gothenburg: Acta Universitatis Gothoburgensis, 1990, viii 132 pp., maps, figs, tbls. - Paul van der Grijp, Pierre Lemonnier, Guerres et festins; Paix, échanges et competition dans les highlands de Nouvelle

  6. Book Reviews

    Directory of Open Access Journals (Sweden)

    R. de Ridder

    1986-01-01

    (50 pp. - R. de Ridder, Dennis Tedlock, The spoken word and the work of interpretation, Philadelphia: University of Pennsylvania Press, 1983. ix + 365 pp., 8 ill. - R. de Ridder, Dennis Tedlock, Popol Vuh, The definitive edition of the Mayan Book of the Dawn of Life and the Glories of Gods and Kings, New York: Simon and Schuster, 1985. 380 pp., 32 ill. - G. van Roon, Dietmar Rothermund, Die Peripherie in der Weltwirtschaftskrise: Afrika, Asien und Lateinamerika 1929-1939, Paderborn: Ferdinand Schýningh, 1983, 295 pp. - Thilo C. Schadeberg, Gýnter Dabitz, Geschichte der erforschung der Nuba-Berge, Arbeiten aus dem Seminar fýr Výlkerkunde der Johann Wolfgang Goethe-Universitýt Frankfurt am Main, Band 17, Wiesbaden: Franz Steiner Verlag, 1985. 280 pp., maps, tables, illus. - L. van Vroonhoven, Ger van Roon, Derde Wereld in depressie, Leiden: Nijhoff, 1985, 139 p. - Wim van Zanten, Nigel Phillips, Sijobang, sung narrative poetry of West Sumatra, Cambridge Studies in Oral and Literate Culture, no. 1, Cambridge: Cambridge University Press, 1981. xi + 255 pp., photos, texts and translations, short glossary of Minangkabau words, Bibliography, index.

  7. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1994-01-01

    Full Text Available -Peter Hulme, Simon Gikandi, Writing in limbo: Modernism and Caribbean literature. Ithaca: Cornell University Press, 1992. x + 260 pp. -Charles V. Carnegie, Alistair Hennessy, Intellectuals in the twentieth-century Caribbean (Volume 1 - Spectre of the new class: The Commonwealth Caribbean. London: Macmillan, 1992. xvii 204 pp. -Nigel Rigby, Anne Walmsley, The Caribbean artists movement, 1966-1972: A literary and cultural history. London: New Beacon Books, 1992. xx + 356 pp. -Carl Pedersen, Tyrone Tillery, Claude McKay: A black poet's struggle for identity. Amherst: University of Massachusetts Press, 1992. xii + 235 pp. -Simone Dreyfus, Irving Rouse, The Tainos: Rise and decline of the people who greeted Columbus. New Haven: Yale University Press, 1992. xii + 211 pp. -Louis Allaire, Antonio M. Stevens-Arroyo, Cave of the Jagua: The mythological world of the Taino. Alburquerque: University of New Mexico Press, 1988. xiii + 282 pp. -Irving Rouse, William F. Keegan, The people who discovered Columbus: The prehistory of the Bahamas. Gainesville: University of Florida Press, 1992. xx + 279 pp. -Neil L. Whitehead, Philip P. Boucher, Cannibal encounters: Europeans and Island Caribs, 1492-1763. Baltimore: John Hopkins University Press, 1992. xii + 217 pp. -Peter Kloos, Kaliña, des amérindiens à Paris: Photographies du prince Roland. Présentées par Gérard Collomb. Paris: Créaphis, 1992. 119 pp. -Maureen Warner-Lewis, Alan Gregor Cobley ,The African-Caribbean connection: Historical and cultural perspectives. Bridgetown, Barbados: Department of History, University of the West Indies, Cave Hill, 1990. viii + 171 pp., Alvin Thompson (eds -H. Hoetink, Jean-Luc Bonniol, La couleur comme maléfice: une illustration créole de la généalogie des 'Blancs' et des 'Noirs'. Paris: Albin Michel, 1992. 304 pp. -Michael Aceto, Richard Price ,Two evenings in Saramaka. Chicago and London: University of Chicago Press, 1991. xvi + 417 pp., Sally Price (eds -Jorge P

  8. Long noncoding RNAs: Lessons from genomic imprinting.

    Science.gov (United States)

    Kanduri, Chandrasekhar

    2016-01-01

    Genomic imprinting has been a great resource for studying transcriptional and post-transcriptional-based gene regulation by long noncoding RNAs (lncRNAs). In this article, I overview the functional role of intergenic lncRNAs (H19, IPW, and MEG3), antisense lncRNAs (Kcnq1ot1, Airn, Nespas, Ube3a-ATS), and enhancer lncRNAs (IG-DMR eRNAs) to understand the diverse mechanisms being employed by them in cis and/or trans to regulate the parent-of-origin-specific expression of target genes. Recent evidence suggests that some of the lncRNAs regulate imprinting by promoting intra-chromosomal higher-order chromatin compartmentalization, affecting replication timing and subnuclear positioning. Whereas others act via transcriptional occlusion or transcriptional collision-based mechanisms. By establishing genomic imprinting of target genes, the lncRNAs play a critical role in important biological functions, such as placental and embryonic growth, pluripotency maintenance, cell differentiation, and neural-related functions such as synaptic development and plasticity. An emerging consensus from the recent evidence is that the imprinted lncRNAs fine-tune gene expression of the protein-coding genes to maintain their dosage in cell. Hence, lncRNAs from imprinted clusters offer insights into their mode of action, and these mechanisms have been the basis for uncovering the mode of action of lncRNAs in several other biological contexts. This article is part of a Special Issue entitled: Clues to long noncoding RNA taxonomy, edited by Dr. Tetsuro Hirose and Dr. Shinichi Nakagawa. PMID:26004516

  9. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1992-01-01

    studies. New Haven, 1990. xiii + 369 pp., W.J. O’Malley, A. Weidemann (eds. - Gisele de Meur, F. Tjon Sie Fat, Representing kinship; Simple models of elementary structures. 1990. (Doctoral thesis. Leiden, published by the author. - Toon van Meijl, Maurice Godelier, Big men and great men; Personifications of power in Melanesia, Cambridge/Paris: Cambridge University Press/Editions de la maison des sciences de l’Homme, 1991, xviii, 328 pp., maps, tables, figures, bibliography, index., Marilyn Strathern (eds. - J.A. de Moor, B.A. Hussainmiya, Orang rejimen; The Malays of the Ceylon rifle regiment. Bangi: Universiti Kebangsaan Malaysia, 1990, 185 pp. - Pieter Muysken, J.M.W. Verhaar, Melanesian pidgin and tok pisin; Studies in language companion series 20. Amsterdam: Benjamins, 1990, xiv + 409 pp. - Niels Mulder, Paul Voogt, Thailand. Amsterdam/’s-Gravenhage: Koninklijk Instituut voor de Tropen/NOVIB, 1991. 70 pp. + kaart, slappe kaft., Han ten Brummelhuis, Irene Stengs (eds. - Ton van Naerssen, George Cho, The Malaysian economy; Spatial perspectives. London: Routledge. 1990, 300 pp. - Julianti Parani, J.R. van Diessen, Jakarta/Batavia. Het centrum van het Nederlandse koloniale rijk in Azië en zijn cultuurhistorische nalatenschap. Cantecleer Kunst - Reisgidsen. De Bilt: Cantecleer, 1989. 343 pp. - A. Ploeg, Christopher J. Healey, Pioneers of the mountain forest, University of Sydney, 1985, Oceania Monographs no. 29, v + 64 pp., plates, figures, maps. - Els Postel-Coster, Carla Risseeuw, The fish don’t talk about the water; Gender transformation, power and resistance among women in Sri Lanka, Leiden: E.J.Brill, 1988, 415 pp., also published as Gender transformation, power and resistance among women in Sri Lanka; The fish don’t speak about the water, New Delhi: Manohar Book service, 1991. Ca. 400 pp., - Willem van Schendel, Mya Tan, Myanmar dilemmas and options; The challenge of economic transition in the 1990’s. Singapore: Institute of Southeast Asian studies, 1990

  10. Spoken Finnish: Book One [and] Book Two.

    Science.gov (United States)

    Sebeok, Thomas A.

    This course in spoken Finnish is intended for use in introductory conversational classes. Book I and Book II, combined in this text, are divided into five major parts, each containing five learning units and one unit devoted to review. Each unit contains sections including (1) basic sentences, (2) word study and review of basic sentences, (3)…

  11. Mycotoxin Analysis Using Imprinted Materials Technology: Recent Developments.

    Science.gov (United States)

    Appell, Michael; Mueller, Anja

    2016-07-01

    Molecular imprinting technology is an attractive, cost-effective, and robust alternative to address the limitations of highly selective natural receptors, such as antibodies and aptamers. The field of molecular imprinting has seen a recent surge in growth, and several commercially available products are of great interest for sample cleanup to improve mycotoxin analysis. Current research trends are in specific applications of imprinting technology for small-molecule sensing and chromatographic cleanup procedures in new commodities. The choice of components and imprinting template are critical factors for mycotoxin recovery or detection optimization. Template mimics offer a means to reduce toxic exposure during polymer synthesis and address issues of leaching template from the imprinted polymer. Recent reports of molecularly imprinted polymers for aflatoxins, ochratoxins, fumonisins, fusaric acid, citrinin, patulin, zearalenone, deoxynivalenol, and T-2 toxin are reviewed. PMID:27214609

  12. Residual-free imprint for sensor definition

    Science.gov (United States)

    Mayer, A.; Bogdanski, N.; Möllenbeck, S.; Scheer, H.-C.

    2009-01-01

    For the preparation of interdigitated sensor devices with nanometre sized electrodes a low-cost route is followed. The central technique used for electrode definition is nanoimprint. To imprint the larger contact areas as easy as the electrodes, the contacts are broken down into a grid. In order to end up with a highly uniform residual layer the concept of 'partial cavity filling' is utilised, resulting in an almost negligible layer thickness. The metallic electrodes are defined by sputtering and lift-off directly after imprint, where a previous etching of the residual layer is not required. The results show that the concept works. With this strategy, preparation of an interdigitated sensor requires nothing but spin-coating, nanoimprinting and sputtering/lift-off.

  13. Keeping Books of Account

    OpenAIRE

    2009-01-01

    Books of account are a record of a company’s income and spending. These records may be kept in paper or electronic form. The books of account contain the information for preparing the company’s annual financial statements.

  14. Making a Memory Book

    Medline Plus

    Full Text Available ... one can do together is make a memory book. Hattie Grossman is 93 years old and still ... have in here is called... it says, "My Book of Memories, made together with," and we'll ...

  15. Making a Memory Book

    Medline Plus

    Full Text Available ... re going to have in here is called... it says, "My Book of Memories, made together with," ... in your book, Grandma. That's why we wanted it... Grossman: This is gorgeous. Geri: ...so that you ...

  16. Nanoscale molecularly imprinted polymers and method thereof

    Science.gov (United States)

    Hart, Bradley R.; Talley, Chad E.

    2008-06-10

    Nanoscale molecularly imprinted polymers (MIP) having polymer features wherein the size, shape and position are predetermined can be fabricated using an xy piezo stage mounted on an inverted microscope and a laser. Using an AMF controller, a solution containing polymer precursors and a photo initiator are positioned on the xy piezo and hit with a laser beam. The thickness of the polymeric features can be varied from a few nanometers to over a micron.

  17. The evolutionary foundation of genomic imprinting in lower vertebrates

    Institute of Scientific and Technical Information of China (English)

    XIE BingHua; ZHANG Lei; ZHENG Kang; LUO Chen

    2009-01-01

    In mammals,genomic imprinting confers developmental asymmetry and complementation on the a-rental genomes and makes both parental genomes essential for complete development.Genomic im-printing is,therefore,the first regulatory step of genome-wide gene expression of embryogeneais and thought to be the epigenetic foundation of bisexual reproduction.However,how the genomic imprint-ing is originated,established and maintained during vertebrate evolution remains unknown.Because no endogenous imprinting gene has been identified in non-mammalian vertebrates,genomic imprinting is thought to be a unique evolutionary event of mammals.Here,in order to study the evolutionary origin of genomic imprinting in vertebrates,we examined whether parent-specific methylation occurred in the teleost homologue of mammalian imprinting gene during gametogenesis.Bisulfate sequencing analy-sis showed that,as mammalian Igf2 CpG island,goldfish Igf2 CpG island was a parental differentially methylated region (DMR) that was hypermethylated in sperm but unmethylated in eggs.Unlike mam-malian imprinting gene DMR,however,the parent-specific methylation pattern of goldfish Igf2 DMR was not maintained during embryogenesis,suggesting that the parent-specific methylation of goldfish Igf2 DMR might be a primitive genomic imprinting in the early period of vertebrate evolution.These results indicate that the evolutionary foundation of genomic imprinting exists in lower vertebrates and ge-nomic imprinting should not be considered as a unique evolutionary event of mammals.

  18. Preparation of imprinted monolithic column under molecular crowding conditions

    Institute of Scientific and Technical Information of China (English)

    Xiao Xia Li; Xin Liu; Li Hong Bai; Hong Quan Duan; Yan Ping Huang; Zhao Sheng Liu

    2011-01-01

    Molecular crowding is a new concept to obtain molecularly imprinted polymers (MIPs) with greater capacity and selectivity. In this work, molecular crowding agent was firstly applied to the preparation of MIPs monolithic column. A new polymerization system based on molecular crowding surrounding was developed to prepare enrofloxacin-imprinted monolith, which was composed of polystyrene and tetrahydrofuran. The result showed that the monolithic MIPs under molecular crowding conditions presented good molecular recognition for enrofloxacin with an imprinting factor of 3.03.

  19. Genome-wide prediction of imprinted murine genes

    OpenAIRE

    Luedi, Philippe P.; Hartemink, Alexander J.; Jirtle, Randy L

    2005-01-01

    Imprinted genes are epigenetically modified genes whose expression is determined according to their parent of origin. They are involved in embryonic development, and imprinting dysregulation is linked to cancer, obesity, diabetes, and behavioral disorders such as autism and bipolar disease. Herein, we train a statistical model based on DNA sequence characteristics that not only identifies potentially imprinted genes, but also predicts the parental allele from which they are expressed. Of 23,7...

  20. Preparation and Property Recognition of Nimodipine Molecularly Imprinted Polymer

    OpenAIRE

    Chen, Fei-Fei

    2015-01-01

    Objective: To explore the application of molecular imprinting technique in the separation and detection of nimodipine. Methods: Methacrylic acid as functional monomer, pentaerythritol triacrylate as cross-linking agent were used to prepare molecularly imprinted polymer (MIP) with the feature of specific recognition performance on imprinting molecule nimodipine under condition of template molecule nimodipine. The preparation conditions, recognition performance of MIP on nimodipine, different p...

  1. BookFinder.com

    CERN Document Server

    BookFinder.com is produced by the bibliophiles at 13th Generation Media of Berkeley, California. Our goal is to provide fellow readers unbiased realtime information about books available online. Rather than selling books ourselves (does the world rea Amazon.com wannabe?), we've teamed up with over 15,000 of the finest booksellers online to bring you the largest book catalog available anywhere, either online or offline.

  2. Companionship of Books

    Institute of Scientific and Technical Information of China (English)

    薛美娟

    2012-01-01

    A man may usually be known by the books he reads as well as by the company he keeps; for there is a companionship of books as well as of men~ and one should always live in the best company, whether it be of books or of men.

  3. Scan This Book!

    Science.gov (United States)

    Albanese, Andrew Richard

    2007-01-01

    In this article, the author presents an interview with Brewster Kahle, leader of the Open Content Alliance (OCA). OCA book scan program is an alternative to Google's library project that aims to make books accessible online. In this interview, Kahle discusses his views on the challenges of getting books on the Web, on Google's library…

  4. Children's Books about Religion.

    Science.gov (United States)

    Dole, Patricia Pearl

    Created to promote a mutual understanding and acceptance among various faiths and cultures throughout the world, this book is an annotated bibliography of religious children's books. It has almost 700 critical evaluations of books with distinct religious themes for children from preschool to middle school. Chapters are: (1) "Religion"; (2) "God";…

  5. Picture Books for Teens.

    Science.gov (United States)

    Kan, Kat

    2002-01-01

    Discusses picture books that are suitable for teens, particularly middle school readers, and provides detailed reviews for five titles that have appealing story themes and illustrations including: Tony Millionaires' Sock Monkey: A Children's Book; Mick Foley's Christmas Chaos; Mick Foley's Halloween Hijinx; The Book of Jack; and Moby Dick. (LRW)

  6. Thinking outside the Book

    Science.gov (United States)

    Eaton, Dolores E.

    2012-01-01

    A title, a cover, and pages with "substance" bound together--this is what the author's eighth-grade students decided were the essential elements of a book. There could be more, but no less. In art, one does judge a book by its cover. In this article, the author describes how her students created their books. (Contains 1 online resource.)

  7. Synthesis of a Molecularly Imprinted Polymer for Dioxin

    Directory of Open Access Journals (Sweden)

    Magda Brattoli

    2006-08-01

    Full Text Available A molecularly imprinted polymer for recognising selectively 2,3,7,8-tetrachlorodibenzodioxin (TCDD was made by a new non-covalent method employing a“dummy” template. The proposed way represents a simplification of a synthetic schemeproposed by Lübke et al.[1] for covalent imprinting. Comparison of extraction yields of thenovel polymer, a non imprinted polymer and an imprinting polymer, prepared by theoriginal procedure demonstrates the binding capacity of the proposed polymer, which is inprinciple applicable to solid phase extraction (SPE of dioxin.

  8. Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation

    OpenAIRE

    Paliwal, Anupam; Temkin, Alexis M.; Kerkel, Kristi; Yale, Alexander; Yotova, Iveta; Drost, Natalia; Lax, Simon; Nhan-Chang, Chia-Ling; Powell, Charles; Borczuk, Alain; Aviv, Abraham; Wapner, Ronald; Chen, Xiaowei; Nagy, Peter L.; Schork, Nicholas,

    2013-01-01

    Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human tissues from methylation-sensitive SNP array data. Two index regions (bisulfite PCR amplicons), one between the C3orf27 and RPN1 genes in chromosome band 3q21 and the other near the VTRNA2-1 vault R...

  9. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

    OpenAIRE

    Anupam Paliwal; Temkin, Alexis M.; Kristi Kerkel; Alexander Yale; Iveta Yotova; Natalia Drost; Simon Lax; Chia-Ling Nhan-Chang; Charles Powell; Alain Borczuk; Abraham Aviv; Ronald Wapner; Xiaowei Chen; Nagy, Peter L.; Nicholas Schork

    2013-01-01

    Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human tissues from methylation-sensitive SNP array data. Two index regions (bisulfite PCR amplicons), one between the C3orf27 and RPN1 genes in chromosome band 3q21 and the other near the VTRNA2-1 vault R...

  10. BOOK REVIEW: Two Books about FRBR, Compared

    Directory of Open Access Journals (Sweden)

    Christine Schwartz

    2008-09-01

    Full Text Available This article reviews 2 books on FRBR published in the past year. Although both books aim to be introductions to FRBR, their approaches are very different. One is sort of a FRBR study guide with commentary, the other a collection of essays. Robert Maxwell's book, FRBR: A Guide for the Perplexed, takes the study guide approach. Arlene Taylor edited Understanding FRBR: What It Is and How It Will Affect Our Retrieval Tools, a book of essays about FRBR and FRAD, written by cataloging experts, aimed at a broader audience, not just the cataloging specialist. The first seven chapters lay out the basics: introductions to FRBR and FRAD, FRBR research, FRBR and the history of cataloging, FRBR and RDA. These chapters provide an excellent introduction for those new to FRBR. The last seven chapters each look at different types of resources in relation to FRBR.

  11. Investigation of imprinting parameters and their recognition nature for quinine-molecularly imprinted polymers

    Science.gov (United States)

    He, Jian-feng; Zhu, Quan-hong; Deng, Qin-ying

    2007-08-01

    A series of molecularly imprinted polymers (MIPs) was prepared using quinine as the template molecules by bulk polymerization. The presence of monomer-template solution complexes in non-covalent MIPs systems has been verified by both fluorescence and UV-vis spectrometric detection. The influence of different synthetic conditions (porogen, functional monomer, cross-linkers, initiation methods, monomer-template ratio, etc.) on recognition properties of the polymers was investigated. Scatchard analysis revealed that two classes of binding sites were formed in the imprinted polymer. The corresponding dissociation constants were estimated to be 45.00 μmol l -1 and 1.42 mmol l -1, respectively, by utilizing a multi-site recognition model. The binding characteristics of the imprinted polymers were explored in various solvents using equilibrium binding experiments. In the organic media, results suggested that polar interactions (hydrogen bonding, ionic interactions, etc.) between acidic monomer/polymer and template molecules were mainly responsible for the recognition, whereas in aqueous media, hydrophobic interactions had a remarkable non-specific contribution to the overall binding. The specificity of MIP was evaluated by rebinding the other structurally similar compounds. The results indicated that the imprinted polymers exhibited an excellent stereo-selectivity toward quinine.

  12. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

    Directory of Open Access Journals (Sweden)

    Anupam Paliwal

    2013-08-01

    Full Text Available Allele-specific DNA methylation (ASM is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human tissues from methylation-sensitive SNP array data. Two index regions (bisulfite PCR amplicons, one between the C3orf27 and RPN1 genes in chromosome band 3q21 and the other near the VTRNA2-1 vault RNA in band 5q31, proved to be new examples of imprinted DMRs (maternal alleles methylated while a third, between STEAP3 and C2orf76 in chromosome band 2q14, showed non-imprinted haplotype-dependent ASM. Using long-read bisulfite sequencing (bis-seq in 8 human tissues we found that in all 3 domains the ASM is restricted to single differentially methylated regions (DMRs, each less than 2kb. The ASM in the C3orf27-RPN1 intergenic region was placenta-specific and associated with allele-specific expression of a long non-coding RNA. Strikingly, the discrete DMRs in all 3 regions overlap with binding sites for the insulator protein CTCF, which we found selectively bound to the unmethylated allele of the STEAP3-C2orf76 DMR. Methylation mapping in two additional genes with non-imprinted haplotype-dependent ASM, ELK3 and CYP2A7, showed that the CYP2A7 DMR also overlaps a CTCF site. Thus, two features of imprinted domains, highly localized DMRs and allele-specific insulator occupancy by CTCF, can also be found in chromosomal domains with non-imprinted ASM. Arguing for biological importance, our analysis of published whole genome bis-seq data from hES cells revealed multiple genome-wide association study (GWAS peaks near CTCF binding sites with ASM.

  13. Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

    Science.gov (United States)

    Paliwal, Anupam; Temkin, Alexis M; Kerkel, Kristi; Yale, Alexander; Yotova, Iveta; Drost, Natalia; Lax, Simon; Nhan-Chang, Chia-Ling; Powell, Charles; Borczuk, Alain; Aviv, Abraham; Wapner, Ronald; Chen, Xiaowei; Nagy, Peter L; Schork, Nicholas; Do, Catherine; Torkamani, Ali; Tycko, Benjamin

    2013-08-01

    Allele-specific DNA methylation (ASM) is well studied in imprinted domains, but this type of epigenetic asymmetry is actually found more commonly at non-imprinted loci, where the ASM is dictated not by parent-of-origin but instead by the local haplotype. We identified loci with strong ASM in human tissues from methylation-sensitive SNP array data. Two index regions (bisulfite PCR amplicons), one between the C3orf27 and RPN1 genes in chromosome band 3q21 and the other near the VTRNA2-1 vault RNA in band 5q31, proved to be new examples of imprinted DMRs (maternal alleles methylated) while a third, between STEAP3 and C2orf76 in chromosome band 2q14, showed non-imprinted haplotype-dependent ASM. Using long-read bisulfite sequencing (bis-seq) in 8 human tissues we found that in all 3 domains the ASM is restricted to single differentially methylated regions (DMRs), each less than 2kb. The ASM in the C3orf27-RPN1 intergenic region was placenta-specific and associated with allele-specific expression of a long non-coding RNA. Strikingly, the discrete DMRs in all 3 regions overlap with binding sites for the insulator protein CTCF, which we found selectively bound to the unmethylated allele of the STEAP3-C2orf76 DMR. Methylation mapping in two additional genes with non-imprinted haplotype-dependent ASM, ELK3 and CYP2A7, showed that the CYP2A7 DMR also overlaps a CTCF site. Thus, two features of imprinted domains, highly localized DMRs and allele-specific insulator occupancy by CTCF, can also be found in chromosomal domains with non-imprinted ASM. Arguing for biological importance, our analysis of published whole genome bis-seq data from hES cells revealed multiple genome-wide association study (GWAS) peaks near CTCF binding sites with ASM. PMID:24009515

  14. Synthesis of molecular imprinted beta cyclodextrins oligomers in water

    DEFF Research Database (Denmark)

    Yu, Donghong; Nielsen, Anne Louise; Bach, Lone;

    2003-01-01

    compounds in aqueous solution and, therefore, molecular imprinting of cyclodextrins polymers in aqueous solution is of great interest. In this paper, molecular imprinting of beta cyclodextrins has been performed in water by use of diiodobenzene as template and epichlorohydrin as a crosslinker. Inclusion...

  15. Imprinting diseases and IVF: Danish National IVF cohort study

    DEFF Research Database (Denmark)

    Lidegaard, Ojvind; Pinborg, Anja; Andersen, Anders Nyboe

    2005-01-01

    The aim of this study was to compare the frequency of imprinting diseases in children born after IVF with the incidence in naturally conceived children.......The aim of this study was to compare the frequency of imprinting diseases in children born after IVF with the incidence in naturally conceived children....

  16. DNA replication: stalling a fork for imprinting and switching

    DEFF Research Database (Denmark)

    Egel, Richard

    2004-01-01

    Mating-type switching in fission yeast has long been known to be directed by a DNA 'imprint'. This imprint has now been firmly characterized as a protected site-specific and strand-specific nick. New work also links the widely conserved Swi1-Swi3 complex to the protection of stalled replication...

  17. AN EVALUATION OF AUDITORY LEARNING IN FILIAL IMPRINTING

    NARCIS (Netherlands)

    BOLHUIS, JJ; VANKAMPEN, HS

    1992-01-01

    The characteristics of auditory learning in filial imprinting in precocial birds are reviewed. Numerous studies have demonstrated that the addition of an auditory stimulus improves following of a visual stimulus. This paper evaluates whether there is genuine auditory imprinting, i.e. the formation o

  18. English Book Club

    CERN Multimedia

    English Book Club

    2012-01-01

    The CERN English Book Club will hold its 2012 AGM at 17h30 on Monday 5th March in the club rooms (club barrack 564). Club members are invited to attend. Any members wishing to add points on to the agenda should contact one of the committee before February 27th. The English Book Club has a collection of over 4500 English language books, mostly general fiction with a sprinkling of nonfiction and children’s books. New books are purchased regularly and the books are shelved in our club room which is accessible to members at all times. Membership is open to all (staff and external) and there is a special tariff for short term students. See the club’s website at http://cern.ch/englishbookclub for more details.

  19. English Book Club

    CERN Multimedia

    CERN English Book Club

    2010-01-01

    AGM  --  AGM  -- 2010 --  AGM  --  AGM The CERN ENGLISH BOOK CLUB will hold its 2010 AGM at 18h00 on Monday November 22nd in the club rooms (club barrack 564). Club members are invited to attend. Any members wishing to add points on to the agenda should contact one of the committee before November 12th. AGM  --  AGM  -- 2010 --  AGM  --  AGM The English Book Club has a collection of over 4500 English language books, mostly general fiction with a sprinkling of nonfiction and children’s books. New books are purchased regularly and the books are shelved in our club room which is accessible to members at all times. Membership is open to all (staff and external) and there is a special tariff for short term students. See the club’s website at http://cern.ch/englishbookclub for more details.  

  20. Open books and plumbings

    OpenAIRE

    Etnyre , John B.; Ozbagci, Burak

    2006-01-01

    We construct, somewhat non-standard, Legendrian surgery diagrams for some Stein fillable contact structures on some plumbing trees of circle bundles over spheres. We then show how to put such a surgery diagram on the pages of an open book for $S^3,$ with relatively low genus. Thus we produce open books with low genus pages supporting these Stein fillable contact structures, and in many cases it can be shown that these open books have minimal genus pages.

  1. Software engineer's pocket book

    CERN Document Server

    Tooley, Michael

    2013-01-01

    Software Engineer's Pocket Book provides a concise discussion on various aspects of software engineering. The book is comprised of six chapters that tackle various areas of concerns in software engineering. Chapter 1 discusses software development, and Chapter 2 covers programming languages. Chapter 3 deals with operating systems. The book also tackles discrete mathematics and numerical computation. Data structures and algorithms are also explained. The text will be of great use to individuals involved in the specification, design, development, implementation, testing, maintenance, and qualit

  2. Electrical engineer's reference book

    CERN Document Server

    Laughton, M A

    1985-01-01

    Electrical Engineer's Reference Book, Fourteenth Edition focuses on electrical engineering. The book first discusses units, mathematics, and physical quantities, including the international unit system, physical properties, and electricity. The text also looks at network and control systems analysis. The book examines materials used in electrical engineering. Topics include conducting materials, superconductors, silicon, insulating materials, electrical steels, and soft irons and relay steels. The text underscores electrical metrology and instrumentation, steam-generating plants, turbines

  3. Functional mapping imprinted quantitative trait loci underlying developmental characteristics

    Directory of Open Access Journals (Sweden)

    Li Gengxin

    2008-03-01

    Full Text Available Abstract Background Genomic imprinting, a phenomenon referring to nonequivalent expression of alleles depending on their parental origins, has been widely observed in nature. It has been shown recently that the epigenetic modification of an imprinted gene can be detected through a genetic mapping approach. Such an approach is developed based on traditional quantitative trait loci (QTL mapping focusing on single trait analysis. Recent studies have shown that most imprinted genes in mammals play an important role in controlling embryonic growth and post-natal development. For a developmental character such as growth, current approach is less efficient in dissecting the dynamic genetic effect of imprinted genes during individual ontology. Results Functional mapping has been emerging as a powerful framework for mapping quantitative trait loci underlying complex traits showing developmental characteristics. To understand the genetic architecture of dynamic imprinted traits, we propose a mapping strategy by integrating the functional mapping approach with genomic imprinting. We demonstrate the approach through mapping imprinted QTL controlling growth trajectories in an inbred F2 population. The statistical behavior of the approach is shown through simulation studies, in which the parameters can be estimated with reasonable precision under different simulation scenarios. The utility of the approach is illustrated through real data analysis in an F2 family derived from LG/J and SM/J mouse stains. Three maternally imprinted QTLs are identified as regulating the growth trajectory of mouse body weight. Conclusion The functional iQTL mapping approach developed here provides a quantitative and testable framework for assessing the interplay between imprinted genes and a developmental process, and will have important implications for elucidating the genetic architecture of imprinted traits.

  4. Give a Book, Take a Book | Poster

    Science.gov (United States)

    Collection has begun for the 15th Annual Book & Media Swap sponsored by the Scientific Library. NCI at Frederick staff can use this opportunity to clear out personal book and DVD shelves of unwanted materials, donate them to the swap, and then receive “new” materials in return. The library staff will collect materials through Tuesday, Oct. 27. Kick-off day for the event is Wednesday, Oct. 28, 10 a.m. to 2 p.m., in the lobby of the Conference Center in Building 549.

  5. Econazole imprinted textiles with antifungal activity.

    Science.gov (United States)

    Hossain, Mirza Akram; Lalloz, Augustine; Benhaddou, Aicha; Pagniez, Fabrice; Raymond, Martine; Le Pape, Patrice; Simard, Pierre; Théberge, Karine; Leblond, Jeanne

    2016-04-01

    In this work, we propose pharmaceutical textiles imprinted with lipid microparticles of Econazole nitrate (ECN) as a mean to improve patient compliance while maintaining drug activity. Lipid microparticles were prepared and characterized by laser diffraction (3.5±0.1μm). Using an optimized screen-printing method, microparticles were deposited on textiles, as observed by scanning electron microscopy. The drug content of textiles (97±3μg/cm(2)) was reproducible and stable up to 4months storage at 25°C/65% Relative Humidity. Imprinted textiles exhibited a thermosensitive behavior, as witnessed by a fusion temperature of 34.8°C, which enabled a larger drug release at 32°C (temperature of the skin) than at room temperature. In vitro antifungal activity of ECN textiles was compared to commercial 1% (wt/wt) ECN cream Pevaryl®. ECN textiles maintained their antifungal activity against a broad range of Candida species as well as major dermatophyte species. In vivo, ECN textiles also preserved the antifungal efficacy of ECN on cutaneous candidiasis infection in mice. Ex vivo percutaneous absorption studies demonstrated that ECN released from pharmaceutical textiles concentrated more in the upper skin layers, where the fungal infections develop, as compared to dermal absorption of Pevaryl®. Overall, these results showed that this technology is promising to develop pharmaceutical garments textiles for the treatment of superficial fungal infections. PMID:26883854

  6. Wordless Books: Picture Perfect

    Science.gov (United States)

    Lukehart, Wendy

    2011-01-01

    Wordless books offer a bounty of riches. The format is accessible to everyone regardless of language or reading ability, making the books ideal for use in international settings, classes with nonnative speakers, or families with adults or children who are struggling or emergent readers. They enrich the aesthetic lives and literacy skills of…

  7. The Book Club Exploded

    Science.gov (United States)

    Hoffert, Barbara

    2006-01-01

    One leader, 12 readers, and a few well-thumbed copies of Jane Austen's "Pride and Prejudice." That is all a book club once required, but this is no longer the case. This article describes how the runaway popularity of book clubs has brought with it a whole new set of possibilities. Thematic discussion? A fiction/nonfiction mix? Videoconferencing?…

  8. Astronomy books in Spanish

    Science.gov (United States)

    Fierro, Julieta

    Great cultures have created language. They have discovered its strength among other reasons for education. For a long time the Bible was one of the few books available in western culture, its influence is beyond any doubt. Many developing nations have no science books in their mother tongue. They might carry a few translations but these do not convey the local culture so it is harder for students to grasp the concepts and to build on what they know. Books, even if they are extremely simple, should be written in local languages because that will facilitate the conveying of knowledge and the creation of scientific culture. In the books examples that pertain to every day local life must be given, in particular examples that have to do with women. Women play a central role in developing nations by child bearing; if they become literate they will influence enormously the quality of their children's education, in particular their science comprehension. In Mexico a collection that includes astronomy books has recently been edited by the National Council for Culture and Arts. The books are small and light, which encourages middle-school students to carry them around and read them while traveling in public transportation, such as the subway. Every other page is a new subject, that carries illustrations, abstracts and conclusions. The astronomy books are on search for extraterrestrial life, the stars and the universe. These books are distributed nation-wide and are inexpensive. They have been written by Mexican astronomers.

  9. The Book of Joshua

    NARCIS (Netherlands)

    Noort, E

    2012-01-01

    "The Book of Joshua contains the papers of the Colloquium Biblicum Lovaniense 2010 on the Book of Joshua and the Land of Israel. Not for the sake of plurality as such, but as a signal of the state of the art in Joshua research in the post-Noth era this volume functions as a platform for different ap

  10. ATLAS Colouring Book

    CERN Multimedia

    Anthony, Katarina

    2016-01-01

    The ATLAS Experiment Colouring Book is a free-to-download educational book, ideal for kids aged 5-9. It aims to introduce children to the field of High-Energy Physics, as well as the work being carried out by the ATLAS Collaboration.

  11. Books in graphs

    OpenAIRE

    Bollobas, Bela; Nikiforov, Vladimir

    2004-01-01

    A book of size $q$ is a set of $q$ triangles sharing a common edge. We study the size of the maximal book in a graph as a function of the number of its edges. In particular, we answer two questions of Erdos about graphs that are union of triangles.

  12. Book and Market.

    NARCIS (Netherlands)

    Marja Appelman; Andries van den Broek

    2002-01-01

    Original title: Boek en markt. The fixed book price is controversial. This evaluation reviews the effectiveness and efficiency of the fixed book price; are the three aims of cultural policy (availability of a wide range of titles, wide accessibility and public participation) being achieved, and bei

  13. Making a Memory Book

    Medline Plus

    Full Text Available ... purpose of the memory book is to enable family members to maintain conversation with a family member who may be having memory difficulties or ... aging and is losing touch with very important family memories. Geri: This is going in your book, ...

  14. More than Comic Books

    Science.gov (United States)

    Boerman-Cornell, Bill

    2013-01-01

    Graphic novels (book-length fiction or nonfiction narratives told using the conventions of a comic book) bring together text and image in a way that seems to capture students' imaginations. Right now, there is little more than anecdotal research about how graphic novels can be used within specific middle school and high school disciplines. As…

  15. China Connections Reference Book.

    Science.gov (United States)

    Kalat, Marie B.; Hoermann, Elizabeth F.

    This reference book focuses on six aspects of the geography of the People's Republic of China. They are: territory, governing units, population and land use, waterways, land forms, and climates. Designed as a primary reference, the book explains how the Chinese people and their lifestyles are affected by China's geography. Special components…

  16. Why Write Book Reviews?

    Science.gov (United States)

    Obeng-Odoom, Franklin

    2014-01-01

    The pressure to publish or perish or, more recently, to be visible or vanish, marginalises a culture of critical reading and reflection that has historically been the province of book reviews. Today, book reviews are roundly rejected by academic bureaucrats as unimportant, easy to write and hence, easy to get published, mere summaries, uncritical…

  17. Data communications pocket book

    CERN Document Server

    Tooley, Michael

    2014-01-01

    Data Communications Pocket Book, Second Edition presents information relevant to data communication. The book provides tabulated reference materials with a brief description and diagrams. The coverage of the text includes abbreviations, terminal control codes, and conversion tables. The text will be of great use to individuals involved in the interconnection of computer systems.

  18. Strawberry Square. Song Book.

    Science.gov (United States)

    Larson, Tom

    Designed to accompany a series of 33 television programs in music education for kindergarten and first grade children, this song book (containing sheet music) correlates with activities in the teacher's guide. Titles of songs included in the book are: Let a Song Tell a Story (short and long versions); If I Had a Hammer; A Happy Street; Let the…

  19. English Book Club

    CERN Multimedia

    English Book Club

    The minutes of the AGM held on Tuesday November 17th can now be found on the club web-site: http://club-englishbookclub.web.cern.ch. A new version of the club’s book data-base is also available on the web: http://club-englishbookclub.web.cern.ch/club-englishbookclub/Export/index.html The last book selection for 2009 is done and the order for the new books has been placed, with luck they will be on the shelves before the end of year break. The English Book Club has a growing collection of over 4500 English language books, mostly general fiction with a sprinkling of nonfiction and children’s books. New books are purchased regularly and the books are shelved in our club room which is accessible to members at all times. Membership is open to all (staff and external) and there is a special tariff for short term students. See the club’s website at http://cern.ch/englishbookclub for more details.

  20. The Obama Books Boom

    Science.gov (United States)

    Roach, Ronald

    2009-01-01

    As Barack Obama's rise to power inspires a flood of books, scholars hope the publishing trend will yield serious analysis. Barack Obama's rise from Illinois politics to the U.S. presidency has inspired authors to produce a flood of books chronicling the 44th commander in chief's life story and political career. Obama's political odyssey invites…

  1. 2010 Renewable Energy Data Book (Book)

    Energy Technology Data Exchange (ETDEWEB)

    Gelman, R.

    2011-10-01

    This Renewable Energy Data Book for 2010 provides facts and figures on energy in general, renewable electricity in the United States, global renewable energy development, wind power, solar energy, geothermal power, biopower, hydropower, advanced water power, hydrogen, renewable fuels, and clean energy investments.

  2. Native American Children's Books. Book Reviews.

    Science.gov (United States)

    Moulton, Kathryn Elizabeth; Cornelius, Carol

    1993-01-01

    Reviews 11 children's books, published 1990-93, suitable for elementary and middle school students, covering Native riddles; Hiawatha as founder of the Iroquois confederacy; Chief Seattle's famous speech; stories about Inuit life and Mexican village life during the 1500s; Sequoyah and the Cherokee alphabet; the Iroquois creation myth; Wampanoag…

  3. 2013 Renewable Energy Data Book (Book)

    Energy Technology Data Exchange (ETDEWEB)

    Esterly, S.

    2014-12-01

    This Renewable Energy Data Book for 2013 provides facts and figures on energy in general, renewable electricity in the United States, global renewable energy development, wind power, solar power, geothermal power, biopower, hydropower, advanced water power, hydrogen, renewable fuels, and clean energy investment.

  4. 2011 Renewable Energy Data Book (Book)

    Energy Technology Data Exchange (ETDEWEB)

    Gelman, R.

    2012-10-01

    This Renewable Energy Data Book for 2011 provides facts and figures on energy in general, renewable electricity in the United States, global renewable energy development, wind power, solar energy, geothermal power, biopower, hydropower, advanced water power, hydrogen, renewable fuels, and clean energy investments.

  5. 2012 Renewable Energy Data Book (Book)

    Energy Technology Data Exchange (ETDEWEB)

    Gelman, R.

    2013-10-01

    This Renewable Energy Data Book for 2012 provides facts and figures in a graphical format on energy in general, renewable electricity in the United States, global renewable energy development, wind power, solar power, geothermal power, biopower, hydropower, advanced water power, hydrogen, renewable fuels, and clean energy investment.

  6. A model for transgenerational imprinting variation in complex traits.

    Science.gov (United States)

    Wang, Chenguang; Wang, Zhong; Luo, Jiangtao; Li, Qin; Li, Yao; Ahn, Kwangmi; Prows, Daniel R; Wu, Rongling

    2010-07-14

    Despite the fact that genetic imprinting, i.e., differential expression of the same allele due to its different parental origins, plays a pivotal role in controlling complex traits or diseases, the origin, action and transmission mode of imprinted genes have still remained largely unexplored. We present a new strategy for studying these properties of genetic imprinting with a two-stage reciprocal F mating design, initiated with two contrasting inbred lines. This strategy maps quantitative trait loci that are imprinted (i.e., iQTLs) based on their segregation and transmission across different generations. By incorporating the allelic configuration of an iQTL genotype into a mixture model framework, this strategy provides a path to trace the parental origin of alleles from previous generations. The imprinting effects of iQTLs and their interactions with other traditionally defined genetic effects, expressed in different generations, are estimated and tested by implementing the EM algorithm. The strategy was used to map iQTLs responsible for survival time with four reciprocal F populations and test whether and how the detected iQTLs inherit their imprinting effects into the next generation. The new strategy will provide a tool for quantifying the role of imprinting effects in the creation and maintenance of phenotypic diversity and elucidating a comprehensive picture of the genetic architecture of complex traits and diseases.

  7. A model for transgenerational imprinting variation in complex traits.

    Directory of Open Access Journals (Sweden)

    Chenguang Wang

    Full Text Available Despite the fact that genetic imprinting, i.e., differential expression of the same allele due to its different parental origins, plays a pivotal role in controlling complex traits or diseases, the origin, action and transmission mode of imprinted genes have still remained largely unexplored. We present a new strategy for studying these properties of genetic imprinting with a two-stage reciprocal F mating design, initiated with two contrasting inbred lines. This strategy maps quantitative trait loci that are imprinted (i.e., iQTLs based on their segregation and transmission across different generations. By incorporating the allelic configuration of an iQTL genotype into a mixture model framework, this strategy provides a path to trace the parental origin of alleles from previous generations. The imprinting effects of iQTLs and their interactions with other traditionally defined genetic effects, expressed in different generations, are estimated and tested by implementing the EM algorithm. The strategy was used to map iQTLs responsible for survival time with four reciprocal F populations and test whether and how the detected iQTLs inherit their imprinting effects into the next generation. The new strategy will provide a tool for quantifying the role of imprinting effects in the creation and maintenance of phenotypic diversity and elucidating a comprehensive picture of the genetic architecture of complex traits and diseases.

  8. Transcriptome-wide investigation of genomic imprinting in chicken

    Science.gov (United States)

    Frésard, Laure; Leroux, Sophie; Servin, Bertrand; Gourichon, David; Dehais, Patrice; Cristobal, Magali San; Marsaud, Nathalie; Vignoles, Florence; Bed'hom, Bertrand; Coville, Jean-Luc; Hormozdiari, Farhad; Beaumont, Catherine; Zerjal, Tatiana; Vignal, Alain; Morisson, Mireille; Lagarrigue, Sandrine; Pitel, Frédérique

    2014-01-01

    Genomic imprinting is an epigenetic mechanism by which alleles of some specific genes are expressed in a parent-of-origin manner. It has been observed in mammals and marsupials, but not in birds. Until now, only a few genes orthologous to mammalian imprinted ones have been analyzed in chicken and did not demonstrate any evidence of imprinting in this species. However, several published observations such as imprinted-like QTL in poultry or reciprocal effects keep the question open. Our main objective was thus to screen the entire chicken genome for parental-allele-specific differential expression on whole embryonic transcriptomes, using high-throughput sequencing. To identify the parental origin of each observed haplotype, two chicken experimental populations were used, as inbred and as genetically distant as possible. Two families were produced from two reciprocal crosses. Transcripts from 20 embryos were sequenced using NGS technology, producing ∼200 Gb of sequences. This allowed the detection of 79 potentially imprinted SNPs, through an analysis method that we validated by detecting imprinting from mouse data already published. However, out of 23 candidates tested by pyrosequencing, none could be confirmed. These results come together, without a priori, with previous statements and phylogenetic considerations assessing the absence of genomic imprinting in chicken. PMID:24452801

  9. The evolution of genomic imprinting: theories, predictions and empirical tests.

    Science.gov (United States)

    Patten, M M; Ross, L; Curley, J P; Queller, D C; Bonduriansky, R; Wolf, J B

    2014-08-01

    The epigenetic phenomenon of genomic imprinting has motivated the development of numerous theories for its evolutionary origins and genomic distribution. In this review, we examine the three theories that have best withstood theoretical and empirical scrutiny. These are: Haig and colleagues' kinship theory; Day and Bonduriansky's sexual antagonism theory; and Wolf and Hager's maternal-offspring coadaptation theory. These theories have fundamentally different perspectives on the adaptive significance of imprinting. The kinship theory views imprinting as a mechanism to change gene dosage, with imprinting evolving because of the differential effect that gene dosage has on the fitness of matrilineal and patrilineal relatives. The sexual antagonism and maternal-offspring coadaptation theories view genomic imprinting as a mechanism to modify the resemblance of an individual to its two parents, with imprinting evolving to increase the probability of expressing the fitter of the two alleles at a locus. In an effort to stimulate further empirical work on the topic, we carefully detail the logic and assumptions of all three theories, clarify the specific predictions of each and suggest tests to discriminate between these alternative theories for why particular genes are imprinted.

  10. A framework for detecting and characterizing genetic background-dependent imprinting effects

    OpenAIRE

    Wolf, Jason B.; Cheverud, James M.

    2009-01-01

    Genomic imprinting, where the effects of alleles depend on their parent-of-origin, can be an important component of the genetic architecture of complex traits. Although there has been a rapidly increasing number of studies of genetic architecture that have examined imprinting effects, none have examined whether imprinting effects depend on genetic background. Such effects are critical for the evolution of genomic imprinting because they allow the imprinting state of a locus to evolve as a fun...

  11. Imprint of Galactic dynamics on Earth's climate

    DEFF Research Database (Denmark)

    Svensmark, Henrik

    2006-01-01

    A connection between climate and the Solar system's motion perpendicular to the Galactic plane during the last 200 Myr years is studied. An imprint of galactic dynamics is found in a long-term record of the Earth's climate that is consistent with variations in the Solar system oscillation around...... the Galactic midplane. From small modulations in the oscillation frequency of Earth's climate the following features of the Galaxy along the Solar circle can be determined: 1) the mass distribution, 2) the timing of two spiral arm crossings (31 Myr and 142 Myr) 3) Spiral arm/interarm density ratio (rho......(arm)/rho(interarm) approximate to 1.5-1.8), and finally, using current knowledge of spiral arm positions, a pattern speed of Omega(P) = 13.6 +/- 1.4 km s(-1) kpc(-1) is determined....

  12. Book Presentation | 27 February

    CERN Multimedia

    The CERN Library

    2013-01-01

    "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo" by Luciano Maiani and Romeo Bassoli, published by Mondadori. On Wednesday 27 February Luciano Maiani will present the book "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo". More information here. The presentation will take place in the Council Chamber at 16.00 and will be followed by a debate and book signing. The book will be on sale. You are cordially invited.

  13. Language Reference Book

    Directory of Open Access Journals (Sweden)

    Miljenko Lapaine

    2012-06-01

    Full Text Available The Coca-Cola HBC Hrvatska Language Reference Book (Jezični priručnik Coca-Cole HBC Hrvatska initially conceived as a practical reference book intended for use within the company is nowadays available to everyone at http://www.prirucnik.hr. The book was prepared by Lana Hudeček and Maja Matković in collaboration with Igor Čutuk and was printed in May 2011 (2nd edition in February 2012 with 274 pages.

  14. Closing the Book

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ When Bertelsmann Direct Group,the music and book direct-marketing arm of German media conglomerate Bertelsmann AG,launched its business in China in 1995,it seemed like a winning idea.The company's book clubs,a catalog mail-order operation offering cut-price books in return for a monthly membership fee,had proven a hugely lucrative business in Europe;and China,with its huge,highly literate population,seemed an ideal market for expansion.

  15. The origin of the RB1 imprint.

    Directory of Open Access Journals (Sweden)

    Deniz Kanber

    Full Text Available The human RB1 gene is imprinted due to a differentially methylated CpG island in intron 2. This CpG island is part of PPP1R26P1, a truncated retrocopy of PPP1R26, and serves as a promoter for an alternative RB1 transcript. We show here by in silico analyses that the parental PPP1R26 gene is present in the analysed members of Haplorrhini, which comprise Catarrhini (Old World Monkeys, Small apes, Great Apes and Human, Platyrrhini (New World Monkeys and tarsier, and Strepsirrhini (galago. Interestingly, we detected the retrocopy, PPP1R26P1, in all Anthropoidea (Catarrhini and Platyrrhini that we studied but not in tarsier or galago. Additional retrocopies are present in human and chimpanzee on chromosome 22, but their distinct composition indicates that they are the result of independent retrotransposition events. Chimpanzee and marmoset have further retrocopies on chromosome 8 and chromosome 4, respectively. To examine the origin of the RB1 imprint, we compared the methylation patterns of the parental PPP1R26 gene and its retrocopies in different primates (human, chimpanzee, orangutan, rhesus macaque, marmoset and galago. Methylation analysis by deep bisulfite sequencing showed that PPP1R26 is methylated whereas the retrocopy in RB1 intron 2 is differentially methylated in all primates studied. All other retrocopies are fully methylated, except for the additional retrocopy on marmoset chromosome 4, which is also differentially methylated. Using an informative SNP for the methylation analysis in marmoset, we could show that the differential methylation pattern of the retrocopy on chromosome 4 is allele-specific. We conclude that the epigenetic fate of a PPP1R26 retrocopy after integration depends on the DNA sequence and selective forces at the integration site.

  16. Cell shape recognition by colloidal cell imprints: Energy of the cell-imprint interaction

    Science.gov (United States)

    Borovička, Josef; Stoyanov, Simeon D.; Paunov, Vesselin N.

    2015-09-01

    The results presented in this study are aimed at the theoretical estimate of the interactions between a spherical microbial cell and the colloidal cell imprints in terms of the Derjaguin, Landau, Vervey, and Overbeek (DLVO) surface forces. We adapted the Derjaguin approximation to take into account the geometry factor in the colloidal interaction between a spherical target particle and a hemispherical shell at two different orientations with respect to each other. We took into account only classical DLVO surface forces, i.e., the van der Waals and the electric double layer forces, in the interaction of a spherical target cell and a hemispherical shell as a function of their size ratio, mutual orientation, distance between their surfaces, their respective surface potentials, and the ionic strength of the aqueous solution. We found that the calculated interaction energies are several orders higher when match and recognition between the target cell and the target cell imprint is achieved. Our analysis revealed that the recognition effect of the hemispherical shell towards the target microsphere comes from the greatly increased surface contact area when a full match of their size and shape is produced. When the interaction between the surfaces of the hemishell and the target cell is attractive, the recognition greatly amplifies the attraction and this increases the likelihood of them to bind strongly. However, if the surface interaction between the cell and the imprint is repulsive, the shape and size match makes this interaction even more repulsive and thus decreases the likelihood of binding. These results show that the surface chemistry of the target cells and their colloidal imprints is very important in controlling the outcome of the interaction, while the shape recognition only amplifies the interaction. In the case of nonmonotonous surface-to-surface interaction we discovered some interesting interplay between the effects of shape match and surface chemistry

  17. Adapting to e-books

    CERN Document Server

    Miller, William

    2013-01-01

    Electronic books are now having a major impact on library collections. This book provides models for acquisitions policies and reports on several surveys of faculty and librarian attitudes toward e-books. It discusses issues in acquiring cataloguing and collection development regarding this important new library resource.Its subject matter deals with the different types of e-books, statistical data available for e-book usage, the development of e-book collections, learning environments, integrating e-books into local catalogues, acquisitions and usage monitoring of e-books.Thi

  18. Dimensional characterization of biperiodic imprinted structures using optical scatterometry

    KAUST Repository

    Gereige, Issam

    2013-12-01

    In this paper, we report on the characterization of biperiodic imprinted structures using a non-destructive optical technique commonly called scatterometry. The nanostructures consist of periodic arrays of square and circular dots which were imprinted in a thermoplastic polymer by thermal nanoimprint lithography. Optical measurements were performed using spectroscopic ellipsometry in the spectral region of 1.5-4 eV. The geometrical profiles of the imprinted structures were reconstructed using the Rigorous Coupled-Wave Analysis (RCWA) to model the diffraction phenomena by periodic gratings. The technique was also adapted for large scale evaluation of the imprint process. Uniqueness of the solution was examined by analyzing the diffraction of the structure at different experimental conditions, for instance at various angles of incidence. © 2013 Elsevier B.V. All rights reserved.

  19. 21 CFR 206.10 - Code imprint required.

    Science.gov (United States)

    2010-04-01

    ... identification than a symbol or logo by itself. Homeopathic drug products are required only to bear an imprint that identifies the manufacturer and their homeopathic nature. (b) A holder of an approved...

  20. Three new Galapagos books

    OpenAIRE

    1984-01-01

    Contents for three books: Galapagos: Volume 2 edited by Roger Perry. Evolution in the Galapagos edited by R.J. Berry. Patterns of Evolution in Galapagos Organisms edited by Robert I. Bowman, Margaret Berson and Alan E. Leviton.

  1. Making a Memory Book

    Medline Plus

    Full Text Available ... Geri's husband and three daughters, Hattie's great-grandchildren. This afternoon they're working on a project with ... losing touch with very important family memories. Geri: This is going in your book, Grandma. That's why ...

  2. Book Reviews 2015

    Directory of Open Access Journals (Sweden)

    Hilling Axel

    2015-12-01

    Full Text Available This section contains three book reviews. First the book Swedish Taxation, Development since 1862 is reviewed. This volume comprises six studies that examine the development of Swedish taxation from 1862 to 2013, and will likely be of great value in future Nordic tax research because of its comprehensiveness. The second review is about a book written in Swedish:Momsfri sjukvård (The VAT exemption for health care. This volume discusses a topical issue and presents convincing recommendations for changes in the Swedish VAT legislation. Finally, the Danish book International Skatteret, i et dansk perspektiv (International Tax Law, in a Danish perspective is presented as highly recommended literature for students and practitioners in the field of international tax law. This volume discusses and illustrates general matters in international tax law, as well as specific matters relevant for Danish international tax law.

  3. Making a Memory Book

    Medline Plus

    Full Text Available ... loved one can do together is make a memory book. Hattie Grossman is 93 years old and ... of years has she had problems with her memory. Just last year she came to live with ...

  4. New Fashioned Book Burning.

    Science.gov (United States)

    Gardner, Robert

    1997-01-01

    Reports on results of a teacher's experiment in book burning as a lesson accompanying the teaching of Ray Bradbury's "Fahrenheit 451." Discusses student reactions and the purpose of or justification for the experimental lesson. (TB)

  5. Making a Memory Book

    Medline Plus

    Full Text Available ... Michelle Bourgeois. Bourgeois: So the first page that we're going to have in here is called... ... My Book of Memories, made together with," and we'll put everyone's name here, "your great-granddaughters." ...

  6. The book house

    DEFF Research Database (Denmark)

    Jensen, Niels Henrik; Agger, Steen

    1989-01-01

    The BOOK HOUSE (and its predecessor, the BOOK AUTOMAT) are computer systems aimed at supporting library users in finding fiction. They are examples of systems using a cognitive work analysis as the basis for design and evaluation - and build on studies of the information retrieval task using actual...... user-librarian negotiations. These studies led to the identification of a set of strategies for searching and retrieving literature as well as a mutri-kimensional framework for classifying fiction. Both of these have been necessary prerequisites for the design of the BOOK HOUSE, a flexible on-line data...... base retrieval system for novice users - both adults and children. The use of icons within a spatial metaphor to facilitate direct manipulation of the displayed objects on the screen forms the basis for the interface in guiding the users' navigation in the BOOK HOUSE. This report, one of three...

  7. Climate Record Books

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Climate Record Books contain daily, monthly, seasonal, and annual averages, extremes, or occurrences. Most data are sequential by period of record 1871-1910,...

  8. Recensione / Recension / Book review

    Directory of Open Access Journals (Sweden)

    Bravo Fabio

    2010-03-01

    Full Text Available Book review of:Sette R., Cases on Technologies for Teaching Criminology and Victimology: Methodologies and practices, IGI Global – Information Science Reference, Hershey PA, 2010

  9. Chitosan in Molecularly-Imprinted Polymers: Current and Future Prospects

    OpenAIRE

    Long Xu; Yun-An Huang; Qiu-Jin Zhu; Chun Ye

    2015-01-01

    Chitosan is widely used in molecular imprinting technology (MIT) as a functional monomer or supporting matrix because of its low cost and high contents of amino and hydroxyl functional groups. The various excellent properties of chitosan, which include nontoxicity, biodegradability, biocompatibility, and attractive physical and mechanical performances, make chitosan a promising alternative to conventional functional monomers. Recently, chitosan molecularly-imprinted polymers have gained consi...

  10. Recognition Interactions of Metal-complexing Imprinted Polymer

    Institute of Scientific and Technical Information of China (English)

    Ying LIU; Guo Sheng DING; Jun De WANG

    2005-01-01

    Molecularly imprinted polymer, exhibiting considerable enantioselectivity for L-mandelic acid, was prepared using metal coordination-chelation interaction. By evaluating the recognition characteristics in the chromatographic mode, the recognition interactions were proposed: specific and nonspecific metal coordination-chelation interaction and hydrophobic interaction were responsible for substrate binding on metal-complexing imprinted polymer; while the selective recognition only came from specific metal coordination-chelation interaction and specific hydrophobic interaction.

  11. Imprint cytology in the diagnosis of ovarian lesions

    OpenAIRE

    Sushma; Sathibhai Panicker

    2015-01-01

    Background: Ovarian neoplasms constitute a major bulk of surgical pathology specimens. Histopathology is the gold standard in diagnosis. Of the many options available for a rapid intra-operative diagnosis imprint cytology has many advantages. This study therefore aimed to study the imprint cytology of ovarian lesions and compare with the histopathology findings and analyze the statistical effectiveness of this study as a rapid intra-operative diagnostic tool. Methods: 200 lesions resected...

  12. Preparation of hydrophilic molecularly imprinted polymers for tetracycline antibiotics recognition

    Institute of Scientific and Technical Information of China (English)

    Peng Wang; Xiao Fang Fu; Jing Li; Jing Luo; Xiao Ya Zhao; Ming Jun Sun; Yin Zhu Shang; Cheng Ye

    2011-01-01

    Hydrophilic molecularly imprinted polymers (MIPs) were prepared using tetracycline as template, methacrylic acid as monomer and glycidilmethacrylate as pro-hydrophilic co-monomer. Compared with common MIPs, the imprinting effect and adsorption amounts of hydrophilic MIPs for tetracycline (TC) were greatly improved in water media. Furthermore, the electrochemical sensor fabricated by modifying hydrophilic MIPs on glassy carbon electrode was developed for the determination of TC in foodstuff samples.

  13. DIAGNOSTIC VALIDITY OF CYTOLOGICAL IMPRINT IN THYROID FOLLICULAR NEOPLASM

    Directory of Open Access Journals (Sweden)

    I Pustaka

    2013-09-01

    Full Text Available Background: Preoperative fine needle aspiration biopsy/FNAB examination, imprint cytology and frozen section intraoperative has big implications for diagnosis and surgical strategy of thyroid nodules with follicular neoplasm cytology. FNAB and frozen section has its limitations, it is difficultto detect the presence of capsular and/or vascular invasion of thyroid follicular carcinoma. Whereas imprint cytology can preserve cellular overview (especially the cell nucleus, including the capsular and/or vascular invasion. In addition, imprint cytology is faster than frozen section. Frozen sectionexamination could not indicate the presence of capsular and/or vascular invasion in most cases so that imprint cytology is used to replace frozen section as an alternative.Method: This research is a diagnostic test study using a descriptive design. This is a prospective study to assess the sensitivity, specificity, NPV, and PPV of imprint cytology in patients with thyroid follicular neoplasm cytology. Results: In our study; sensitivity, specificity, PPV, NPV, and accuracy of imprint cytology for follicular neoplasm was found as 84.21%, 95.45%, 94.12%, 87.50% and 90.24% respectively. The outcome was based on likelihood ratio value of 18.21 and the ROC curve, area under the curve obtained at 0.879 and Kappa value of 0.802.Conclusion: Imprint cytology has a value of a gooddiagnostic validity in the diagnosis of follicular neoplasm of thyroid nodules with sensitivity and specifity values of 84.21% and 95.45%. Imprint cytology is a technique that is simple, inexpensive, and has good reliability so that it can be used instead of frozen section.

  14. Separation of tryptophan enantiomers with molecularly imprinted polypyrrole electrode column

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this study,we have fabricated molecularly imprinted polypyrrole(PPy) packed electrode columns and investigated their effects on separation of tryptophan(Trp) enantiomers by using potential control.The results indicate that the imprinted PPy electrode columns could efficiently enhance the L-Trp uptake and separate Trp enantiomers effectively,implying the great potential for the enantioselective recognition of other amino acids enantiomers.

  15. UV imprinting for thin film solar cell application

    Science.gov (United States)

    Escarré, J.; Battaglia, C.; Söderström, K.; Pahud, C.; Biron, R.; Cubero, O.; Haug, F.-J.; Ballif, C.

    2012-02-01

    UV imprinting is an interesting, low cost technique to produce large area thin film solar cells incorporating nanometric textures. Here, we review and present new results confirming that replicas of the most common textures used in photovoltaics can be obtained by UV imprinting with an excellent fidelity. The use of these replicas as substrates for amorphous and micromorph thin film silicon solar cells is also shown, together with a comparison with devices obtained on the original textures.

  16. UV imprinting for thin film solar cell application

    OpenAIRE

    Escarre, J; Battaglia, C; Soederstroem, K.; Pahud, C.; Biron, R.; Cubero, O.; Haug, F.-J.; Ballif, C.

    2012-01-01

    UV imprinting is an interesting, low cost technique to produce large area thin film solar cells incorporating nanometric textures. Here, we review and present new results confirming that replicas of the most common textures used in photovoltaics can be obtained by UV imprinting with an excellent fidelity. The use of these replicas as substrates for amorphous and micromorph thin film silicon solar cells is also shown, together with a comparison with devices obtained on the original textures.

  17. Full-field imprinting of sub-40 nm patterns

    Science.gov (United States)

    Yeo, Jeongho; Kim, Hoyeon; Eynon, Ben

    2008-03-01

    Imprint lithography has been included on the ITRS Lithography Roadmap at the 32, 22 and 16 nm nodes. Step and Flash Imprint Lithography (S-FIL (R)) is a unique patterning method that has been designed from the beginning to enable precise overlay to enable multilevel device fabrication. A photocurable low viscosity resist is dispensed dropwise to match the pattern density requirements of the device, thus enabling patterning with a uniform residual layer thickness across a field and across multiple wafers. Further, S-FIL provides sub-50 nm feature resolution without the significant expense of multi-element projection optics or advanced illumination sources. However, since the technology is 1X, it is critical to address the infrastructure associated with the fabrication of imprint masks (templates). For sub-32 nm device manufacturing, one of the major technical challenges remains the fabrication of full-field 1x imprint masks with commercially viable write times. Recent progress in the writing of sub-40 nm patterns using commercial variable shape e-beam tools and non-chemically amplified resists has demonstrated a very promising route to realizing these objectives, and in doing so, has considerably strengthened imprint lithography as a competitive manufacturing technology for the sub-32nm node. Here we report the first imprinting results from sub-40 nm full-field patterns, using Samsung's current flash memory production device design. The fabrication of the imprint mask and the resulting critical dimension control and uniformity are discussed, along with image placement results. The imprinting results are described in terms of CD uniformity, etch results, and overlay.

  18. Safari Books Online Platform

    OpenAIRE

    B. Struyf

    2005-01-01

    When two leading publishers of technical information wanted to transform concept into reality, they tapped into the expertise of Bureau van Dijk Electronic Publishing (http://eps.bvdep.com) for development, support andhosting. The Concept? Using the Web to provide a virtual library of technical books. The reality? The highly successful Safari Books Online, LLC, a joint venture of O’Reilly & Associates and Pearson Technology Group, has become the premier electronic reference library for Inform...

  19. Electronics engineer's reference book

    CERN Document Server

    Turner, L W

    1976-01-01

    Electronics Engineer's Reference Book, 4th Edition is a reference book for electronic engineers that reviews the knowledge and techniques in electronics engineering and covers topics ranging from basics to materials and components, devices, circuits, measurements, and applications. This edition is comprised of 27 chapters; the first of which presents general information on electronics engineering, including terminology, mathematical equations, mathematical signs and symbols, and Greek alphabet and symbols. Attention then turns to the history of electronics; electromagnetic and nuclear radiatio

  20. Books 'n' stuff

    DEFF Research Database (Denmark)

    Christoffersen, Ellen

    2007-01-01

    The book "Kommunikations-Controlling" by Manfred Piwinger/Viktor Porák (eds.) is an interim report in which several authors analyse the state of the art in the discussion of communications controlling.......The book "Kommunikations-Controlling" by Manfred Piwinger/Viktor Porák (eds.) is an interim report in which several authors analyse the state of the art in the discussion of communications controlling....

  1. Book Review: Stop, Write!

    Directory of Open Access Journals (Sweden)

    Hans Thulesius

    2013-06-01

    Full Text Available This book on writing grounded theory is intended for the empirical GT researcher who wants to pursue his/her research until publication. It is the first book devoted entirely to such a crucial issue as writing grounded theory. Thus, Stop, Write: Writing Grounded Theory, is a practical book that fills a gap in GT methodology. In the first chapter of the book, Dr. Glaser says, “Stop unending conceptualization, unending data coverage, and unending listening to others who would egg you on with additional data, ideas and/or requirements or simply wait too long”. The book teaches the reader how to actually write a grounded theory by “simply” writing up the sorted memos. This requires efficient sorting that is dealt with in chapter two on Sorting Memos, which includes precious repetition from Theoretical Sensitivity (1978. How writing can be done effectively is outlined in chapter three The Working Paper. Then follows chapter four on how to rework the first draft with the different tasks of editing for language and professionalism. Thereafter Dr. Glaser discusses Writing Problems in chapter five where he gives useful guidance on how to overcome writing blocks and problems with supervisors and dissertation committees. The book also deals with publishing and with collaboration as experienced between Barney Glaser and the cofounder of grounded theory, Anselm Strauss.

  2. Sequences sufficient for programming imprinted germline DNA methylation defined.

    Directory of Open Access Journals (Sweden)

    Yoon Jung Park

    Full Text Available Epigenetic marks are fundamental to normal development, but little is known about signals that dictate their placement. Insights have been provided by studies of imprinted loci in mammals, where monoallelic expression is epigenetically controlled. Imprinted expression is regulated by DNA methylation programmed during gametogenesis in a sex-specific manner and maintained after fertilization. At Rasgrf1 in mouse, paternal-specific DNA methylation on a differential methylation domain (DMD requires downstream tandem repeats. The DMD and repeats constitute a binary switch regulating paternal-specific expression. Here, we define sequences sufficient for imprinted methylation using two transgenic mouse lines: One carries the entire Rasgrf1 cluster (RC; the second carries only the DMD and repeats (DR from Rasgrf1. The RC transgene recapitulated all aspects of imprinting seen at the endogenous locus. DR underwent proper DNA methylation establishment in sperm and erasure in oocytes, indicating the DMD and repeats are sufficient to program imprinted DNA methylation in germlines. Both transgenes produce a DMD-spanning pit-RNA, previously shown to be necessary for imprinted DNA methylation at the endogenous locus. We show that when pit-RNA expression is controlled by the repeats, it regulates DNA methylation in cis only and not in trans. Interestingly, pedigree history dictated whether established DR methylation patterns were maintained after fertilization. When DR was paternally transmitted followed by maternal transmission, the unmethylated state that was properly established in the female germlines could not be maintained. This provides a model for transgenerational epigenetic inheritance in mice.

  3. Seeing into Books: Lessons from Rare Book School

    Science.gov (United States)

    Hendrickson, Lois G.

    2012-01-01

    Recently, the author spent a week at Rare Book School (RBS) immersed in a course entitled "Teaching the History of the Book;" an investigation into different ways of thinking about, designing, and conducting a course on the history of the book. The goal was to learn how to convert teaching and outreach experiences in rare book collections from a…

  4. Do Adolescents Prefer Electronic Books to Paper Books?

    OpenAIRE

    Margaret K. Merga

    2015-01-01

    While electronic books offer a range of benefits and may be supposed to be more appealing to young people than paper books, this assumption is often treated as fact by educational researchers. Understanding adolescents’ true current preferences is essential, as incorrect assumptions can lead to decisions which restrict adolescent access to their preferred book mode. The belief that adolescents prefer electronic books to paper books has already led to some school libraries being expunged of pa...

  5. BOOK REVIEW: Physics 1

    Science.gov (United States)

    Sang, David; Gibbs, Keith; Hutchings, Robert

    2000-09-01

    Physics 1 is an attractive book designed to cover the whole of the AS physics course and has been endorsed by OCR for its Advanced AS and A2 specifications. Built on books from the Cambridge Modular Sciences series, it provides a clearly presented path through each of the three sections: Foundation Physics, Electrons and Photons, and Wave Properties. Each chapter has clearly stated objectives and is peppered with self-assessment questions, the answers to all of which are at the back of the book. Additional questions are given at the end of each chapter. There is an excellent use of colour, summary boxes and diagrams, but relatively few photographs. At the back of the book is a useful section on uncertainties and a glossary. The key feature of this book is its accessibility to students coming from a double-award science background. A great deal of thought has gone into lessening the trauma of the transition to Advanced Level and the results are impressive. Some of the main areas of concern for many students are the mathematical sections. These areas are not rushed, especially in the foundation physics, where there are plenty of worked examples. It is assumed, also, that students will not necessarily be confident with graphs so lots of examples are given. Diagrams of the type of practical equipment students are likely to encounter add another dimension to the book. It is good to see the use of light gates and motion sensors in addition to the more traditional ticker-timers for the calculations of speed and acceleration. Accessibility is the strength of this book. The use of colour and space, as well as the content, make it enjoyable to use and to read for any student embarking on the new AS courses. Helen Reynolds

  6. Distinguishing epigenetic marks of developmental and imprinting regulation

    Directory of Open Access Journals (Sweden)

    McEwen Kirsten R

    2010-01-01

    Full Text Available Abstract Background The field of epigenetics is developing rapidly, however we are only beginning to comprehend the complexity of its influence on gene regulation. Using genomic imprinting as a model we examine epigenetic profiles associated with different forms of gene regulation. Imprinting refers to the expression of a gene from only one of the chromosome homologues in a parental-origin-specific manner. This is dependent on heritable germline epigenetic control at a cis-acting imprinting control region that influences local epigenetic states. Epigenetic modifications associated with imprinting regulation can be compared to those associated with the more canonical developmental regulation, important for processes such as differentiation and tissue specificity. Here we test the hypothesis that these two mechanisms are associated with different histone modification enrichment patterns. Results Using high-throughput data extraction with subsequent analysis, we have found that particular histone modifications are more likely to be associated with either imprinting repression or developmental repression of imprinted genes. H3K9me3 and H4K20me3 are together enriched at imprinted genes with differentially methylated promoters and do not show a correlation with developmental regulation. H3K27me3 and H3K4me3, however, are more often associated with developmental regulation. We find that imprinted genes are subject to developmental regulation through bivalency with H3K4me3 and H3K27me3 enrichment on the same allele. Furthermore, a specific tri-mark signature comprising H3K4me3, H3K9me3 and H4K20me3 has been identified at all imprinting control regions. Conclusion A large amount of data is produced from whole-genome expression and epigenetic profiling studies of cellular material. We have shown that such publicly available data can be mined and analysed in order to generate novel findings for categories of genes or regulatory elements. Comparing two

  7. When Do Children Read Books?

    Science.gov (United States)

    van Ours, Jan C.

    2008-01-01

    This paper investigates the reading of fiction books by 15 year olds in 18 OECD countries. It appears that girls read fiction books more often than boys, whereas boys read comic books more often than girls. Parental education, family structure, and the number of books and televisions at home influence the intensity with which children read fiction…

  8. ENGLISH BOOK CLUB

    CERN Multimedia

    English Book Club

    2009-01-01

    http://club-englishbookclub.web.cern.ch A note to our members Dear Members, Many thanks to all of you who have paid up now. However, there are still some late payers and Morna would appreciate knowing if they will pay for 2009/2010 or if they have left the club. At the AGM on 17 November it was decided that a 3 month delay for key reimbursement will be given to all present and past members, BUT after 31.3.2010 no reimbursement will be given out. We are in the process of making changes to the access to the club for paid-up, active members only. Some of you have told Morna you will pay on your next visit to CERN, that is ok but please try to do this by 15 December if possible. A new version of the club’s book data-base is available on the web: http://club-englishbookclub.web.cern.ch/club-englishbookclub/Export/index.html The English Book Club has a growing collection of over 4500 English language books, mostly general fiction with a sprinkling of nonfiction and children’s books. New books...

  9. Non-coding RNAs and the acquisition of genomic imprinting in mammals

    Institute of Scientific and Technical Information of China (English)

    ZHANG YiJun; QU LiangHu

    2009-01-01

    Genomic imprinting, representing parent-specific expression of alleles at a locus, Is mainly evident in flowering plants and placental mammals. Most imprinted genes, including numerous non-coding RNAs, are located in clusters regulated by imprinting control regions (ICRs). The acquisition and evolution of genomic imprinting is among the most fundamental genetic questions. Discoveries about the transition of mammalian imprinted gene domains from their non-imprinted ancestors, especially recent studies undertaken on the most ancient mammalian clades - the marsupials and monotremes from which model species genomes have recently been sequenced, are of high value. By reviewing and analyzing these studies, a close connection between non-coding RNAs and the acquisition of genomic imprinting in mammals is demonstrated. The evidence comes from two observations accompanied with the ac-quisition of the imprinting: (i) many novel non-coding RNA genes emerged in imprinted regions; (ii) the expressions of some conserved non-coding RNAs have changed dramatically. Furthermore, a system-atical analysis of imprinted snoRNA (small nucleolar RNA) genes from 15 vertebrates suggests that the origination of imprinted snoRNAs occurred after the divergence between eutherians and marsupials, followed by a rapid expansion leading to the fixation of major gene families in the eutherian ancestor prior to the radiation of modern placental mammals. Involved in the regulation of imprinted silencing and mediating the ohromatins epigenetic modification may be the major roles that non-coding RNAs play during the acquisition of genomic imprinting in mammals.

  10. Resources: E-Book Readers

    OpenAIRE

    Brenner, Daniel; Kelley, Todd R.

    2008-01-01

    The article provides information on the resources of electronic book (e-book) reader. It cites that an e-book reader is a device where people can download, store, and read printed materials. However, e-book readers are not applicable in educational setting because textbooks are not yet available for download. There are funding programs for e-books readers in schools emerged like Target Early Childhood Reading Grants, HP Technology for Teaching Grant Initiative, and EDS Technology Grant Program.

  11. Bisphenol a exposure disrupts genomic imprinting in the mouse.

    Directory of Open Access Journals (Sweden)

    Martha Susiarjo

    2013-04-01

    Full Text Available Exposure to endocrine disruptors is associated with developmental defects. One compound of concern, to which humans are widely exposed, is bisphenol A (BPA. In model organisms, BPA exposure is linked to metabolic disorders, infertility, cancer, and behavior anomalies. Recently, BPA exposure has been linked to DNA methylation changes, indicating that epigenetic mechanisms may be relevant. We investigated effects of exposure on genomic imprinting in the mouse as imprinted genes are regulated by differential DNA methylation and aberrant imprinting disrupts fetal, placental, and postnatal development. Through allele-specific and quantitative real-time PCR analysis, we demonstrated that maternal BPA exposure during late stages of oocyte development and early stages of embryonic development significantly disrupted imprinted gene expression in embryonic day (E 9.5 and 12.5 embryos and placentas. The affected genes included Snrpn, Ube3a, Igf2, Kcnq1ot1, Cdkn1c, and Ascl2; mutations and aberrant regulation of these genes are associated with imprinting disorders in humans. Furthermore, the majority of affected genes were expressed abnormally in the placenta. DNA methylation studies showed that BPA exposure significantly altered the methylation levels of differentially methylated regions (DMRs including the Snrpn imprinting control region (ICR and Igf2 DMR1. Moreover, exposure significantly reduced genome-wide methylation levels in the placenta, but not the embryo. Histological and immunohistochemical examinations revealed that these epigenetic defects were associated with abnormal placental development. In contrast to this early exposure paradigm, exposure outside of the epigenetic reprogramming window did not cause significant imprinting perturbations. Our data suggest that early exposure to common environmental compounds has the potential to disrupt fetal and postnatal health through epigenetic changes in the embryo and abnormal development of the

  12. Molecularly imprinted Ru complex catalysts integrated on oxide surfaces.

    Science.gov (United States)

    Muratsugu, Satoshi; Tada, Mizuki

    2013-02-19

    Selective catalysis is critical for the development of green chemical processes, and natural enzymes that possess specialized three-dimensional reaction pockets with catalytically active sites represent the most sophisticated systems for selective catalysis. A reaction space in an enzyme consists of an active metal center, functional groups for molecular recognition (such as amino acids), and a surrounding protein matrix to prepare the reaction pocket. The artificial design of such an integrated catalytic unit in a non-enzymatic system remains challenging. Molecular imprinting of a supported metal complex provides a promising approach for shape-selective catalysis. In this process, an imprinted cavity with a shape matched to a template molecule is created in a polymer matrix with a catalytically active metal site. In this Account, we review our studies on molecularly imprinted metal complex catalysts, focusing on Ru complexes, on oxide surfaces for shape-selective catalysis. Oxide surface-attached transition metal complex catalysts not only improve thermal stability and catalyst dispersion but also provide unique catalytic performance not observed in homogeneous precursors. We designed molecularly imprinted Ru complexes by using surface-attached Ru complexes with template ligands and inorganic/organic surface matrix overlayers to control the chemical environment around the active metal complex catalysts on oxide surfaces. We prepared the designed, molecularly imprinted Ru complexes on SiO(2) surfaces in a step-by-step manner and characterized them with solid-state (SS) NMR, diffuse-reflectance (DR) UV-vis, X-ray photoelectron spectroscopy (XPS), Brunauer-Emmett-Teller isotherm (BET), X-ray fluorescence (XRF), and Ru K-edge extended X-ray absorption fine structure (EXAFS). The catalytic performances of these Ru complexes suggest that this process of molecular imprinting facilitates the artificial integration of catalytic functions at surfaces. Further advances such

  13. Parental genome dosage imbalance deregulates imprinting in Arabidopsis.

    Directory of Open Access Journals (Sweden)

    Pauline E Jullien

    2010-03-01

    Full Text Available In mammals and in plants, parental genome dosage imbalance deregulates embryo growth and might be involved in reproductive isolation between emerging new species. Increased dosage of maternal genomes represses growth while an increased dosage of paternal genomes has the opposite effect. These observations led to the discovery of imprinted genes, which are expressed by a single parental allele. It was further proposed in the frame of the parental conflict theory that parental genome imbalances are directly mirrored by antagonistic regulations of imprinted genes encoding maternal growth inhibitors and paternal growth enhancers. However these hypotheses were never tested directly. Here, we investigated the effect of parental genome imbalance on the expression of Arabidopsis imprinted genes FERTILIZATION INDEPENDENT SEED2 (FIS2 and FLOWERING WAGENINGEN (FWA controlled by DNA methylation, and MEDEA (MEA and PHERES1 (PHE1 controlled by histone methylation. Genome dosage imbalance deregulated the expression of FIS2 and PHE1 in an antagonistic manner. In addition increased dosage of inactive alleles caused a loss of imprinting of FIS2 and MEA. Although FIS2 controls histone methylation, which represses MEA and PHE1 expression, the changes of PHE1 and MEA expression could not be fully accounted for by the corresponding fluctuations of FIS2 expression. Our results show that parental genome dosage imbalance deregulates imprinting using mechanisms, which are independent from known regulators of imprinting. The complexity of the network of regulations between expressed and silenced alleles of imprinted genes activated in response to parental dosage imbalance does not support simple models derived from the parental conflict hypothesis.

  14. The "silent" imprint of musical training.

    Science.gov (United States)

    Klein, Carina; Liem, Franziskus; Hänggi, Jürgen; Elmer, Stefan; Jäncke, Lutz

    2016-02-01

    Playing a musical instrument at a professional level is a complex multimodal task requiring information integration between different brain regions supporting auditory, somatosensory, motor, and cognitive functions. These kinds of task-specific activations are known to have a profound influence on both the functional and structural architecture of the human brain. However, until now, it is widely unknown whether this specific imprint of musical practice can still be detected during rest when no musical instrument is used. Therefore, we applied high-density electroencephalography and evaluated whole-brain functional connectivity as well as small-world topologies (i.e., node degree) during resting state in a sample of 15 professional musicians and 15 nonmusicians. As expected, musicians demonstrate increased intra- and interhemispheric functional connectivity between those brain regions that are typically involved in music perception and production, such as the auditory, the sensorimotor, and prefrontal cortex as well as Broca's area. In addition, mean connectivity within this specific network was positively related to musical skill and the total number of training hours. Thus, we conclude that musical training distinctively shapes intrinsic functional network characteristics in such a manner that its signature can still be detected during a task-free condition. Hum Brain Mapp 37:536-546, 2016. © 2015 Wiley Periodicals, Inc. PMID:26538421

  15. Mechanical engineer's reference book

    CERN Document Server

    Parrish, A

    1973-01-01

    Mechanical Engineer's Reference Book: 11th Edition presents a comprehensive examination of the use of Systéme International d' Unités (SI) metrication. It discusses the effectiveness of such a system when used in the field of engineering. It addresses the basic concepts involved in thermodynamics and heat transfer. Some of the topics covered in the book are the metallurgy of iron and steel; screw threads and fasteners; hole basis and shaft basis fits; an introduction to geometrical tolerancing; mechanical working of steel; high strength alloy steels; advantages of making components as castings

  16. Electrical engineer's reference book

    CERN Document Server

    Jones, G R

    2013-01-01

    A long established reference book: radical revision for the fifteenth edition includes complete rearrangement to take in chapters on new topics and regroup the subjects covered for easy access to information.The Electrical Engineer's Reference Book, first published in 1945, maintains its original aims: to reflect the state of the art in electrical science and technology and cater for the needs of practising engineers. Most chapters have been revised and many augmented so as to deal properly with both fundamental developments and new technology and applications that have come to the fore since

  17. Web designer's idea book

    CERN Document Server

    McNeil, Patrick

    2014-01-01

    Discover the latest trends in web design! Looking for inspiration for your latest web design project? Expert Patrick McNeil, author of the popular Web Designer's Idea Book series, is back with all new examples of today's best website design. Featuring more than 650 examples of the latest trends, this fourth volume of The Web Designer's Idea Book is overflowing with visual inspiration. Arranged categorically, this fully illustrated guide puts important topics like design styles, elements, themes and responsive design at your fingertips. This new volume also includes a detailed discussion o

  18. Newnes electrical pocket book

    CERN Document Server

    Reeves, E A

    2013-01-01

    Newnes Electrical Pocket Book, Twenty-first Edition, provides engineers with convenient access to various facts, tables, and formulae relating to the particular branch of engineering being dealt with. In the case of electrical engineering, it is essential that the engineer have a clear understanding of the methods by which the various formulae are derived to ensure that any particular formulae is applicable to the conditions being considered. The first section of the Pocket Book is devoted to the theoretical groundwork upon which all the practical applications are based. This covers symbols,

  19. The MCAT Physics Book

    CERN Document Server

    Biehle, Garrett

    2012-01-01

    Comprehensive, Rigorous Prep for MCAT Physics. The MCAT Physics Book offers the most comprehensive and rigorous analysis of MCAT physics available. Including,. Features:. * 500 MCAT-style practice problems and detailed solutions to all problems. * 49 MCAT-style passages. Illustrations and tables are included wherever necessary to focus and clarify key ideas and concepts. Dr. Biehle's classic MCAT Physics Book presents a clear, insightful analysis of MCAT physics. His lively prose and subtle wit make this challenging topic more palatable. Dr. Biehle received his Ph.D. from Caltech (California I

  20. CMS Comic Book

    CERN Document Server

    Gill, Karl Aaron

    2006-01-01

    Titled "CMS Particle Hunter," this colorful comic book style brochure explains to young budding scientists and science enthusiasts in colorful animation how the CMS detector was made, its main parts, and what scientists hope to find using this complex tool. Book invites young students to get involved in particle physics themselves to join the adventure. Written by Dave Barney and Aline Guevera. Layout and drawings by Eric Paiharey and Frederic Vignaux. Available in English, French, German, Italian, Spanish and Portuguese. Year Produced: 2006. Update: September 2013.

  1. Electronics pocket book

    CERN Document Server

    Parr, E A

    1981-01-01

    Electronics Pocket Book, Fourth Edition is a nonmathematical presentation of the many varied topics covered by electronics. The book tackles electron physics, electronic components (i.e. resistors, capacitors, and conductors), integrated circuits, and the principles of a.c. and d.c. amplifiers. The text also discusses oscillators, digital circuits, digital computers, and optoelectronics (i.e., sensors, emitters, and devices that utilize light). Communications (such as line and radio communications, transmitters, receivers, and digital techniques); the principles and examples of servosystems; a

  2. Newnes microprocessor pocket book

    CERN Document Server

    Money, Steve

    2014-01-01

    Newnes Microprocessor Pocket Book explains the basic hardware operation of a microprocessor and describes the actions of the various types of instruction that can be executed. A summary of the characteristics of many of the popular microprocessors is presented. Apart from the popular 8- and 16-bit microprocessors, some details are also given of the popular single chip microcomputers and of the reduced instruction set computer (RISC) type processors such as the Transputer, Novix FORTH processor, and Acorn ARM processor.Comprised of 15 chapters, this book discusses the principles involved in bot

  3. Electronics engineer's reference book

    CERN Document Server

    Mazda, F F

    1989-01-01

    Electronics Engineer's Reference Book, Sixth Edition is a five-part book that begins with a synopsis of mathematical and electrical techniques used in the analysis of electronic systems. Part II covers physical phenomena, such as electricity, light, and radiation, often met with in electronic systems. Part III contains chapters on basic electronic components and materials, the building blocks of any electronic design. Part IV highlights electronic circuit design and instrumentation. The last part shows the application areas of electronics such as radar and computers.

  4. Chemistry WebBook

    Science.gov (United States)

    SRD 69 NIST Chemistry WebBook (Web, free access)   The NIST Chemistry WebBook contains: Thermochemical data for over 7000 organic and small inorganic compounds; thermochemistry data for over 8000 reactions; IR spectra for over 16,000 compounds; mass spectra for over 33,000 compounds; UV/Vis spectra for over 1600 compounds; electronic and vibrational spectra for over 5000 compounds; constants of diatomic molecules(spectroscopic data) for over 600 compounds; ion energetics data for over 16,000 compounds; thermophysical property data for 74 fluids.

  5. Highly Selective Fluorescent Sensing of Proteins Based on a Fluorescent Molecularly Imprinted Nanosensor

    Directory of Open Access Journals (Sweden)

    Shuo Wang

    2013-09-01

    Full Text Available A fluorescent molecularly imprinted nanosensor was obtained by grafting imprinted polymer onto the surface of multi-wall carbon nanotubes and post-imprinting treatment with fluorescein isothiocyanate (FITC. The fluorescence of lysozyme-imprinted polymer (Lys-MIP was quenched more strongly by Lys than that of nonimprinted polymer (NIP, which indicated that the Lys-MIP could recognize Lys. The resulted imprinted material has the ability to selectively sense a target protein, and an imprinting factor of 3.34 was achieved. The Lys-MIP also showed selective detection for Lys among other proteins such as cytochrome C (Cyt C, hemoglobin (HB and bovine serum albumin (BSA due to the imprinted sites in the Lys-MIP. This approach combines the high selectivity of surface molecular imprinting technology and fluorescence, and converts binding events into detectable signals by monitoring fluorescence spectra. Therefore, it will have further applications for Lys sensing.

  6. Bio-Mimetic Sensors Based on Molecularly Imprinted Membranes

    Directory of Open Access Journals (Sweden)

    Catia Algieri

    2014-07-01

    Full Text Available An important challenge for scientific research is the production of artificial systems able to mimic the recognition mechanisms occurring at the molecular level in living systems. A valid contribution in this direction resulted from the development of molecular imprinting. By means of this technology, selective molecular recognition sites are introduced in a polymer, thus conferring it bio-mimetic properties. The potential applications of these systems include affinity separations, medical diagnostics, drug delivery, catalysis, etc. Recently, bio-sensing systems using molecularly imprinted membranes, a special form of imprinted polymers, have received the attention of scientists in various fields. In these systems imprinted membranes are used as bio-mimetic recognition elements which are integrated with a transducer component. The direct and rapid determination of an interaction between the recognition element and the target analyte (template was an encouraging factor for the development of such systems as alternatives to traditional bio-assay methods. Due to their high stability, sensitivity and specificity, bio-mimetic sensors-based membranes are used for environmental, food, and clinical uses. This review deals with the development of molecularly imprinted polymers and their different preparation methods. Referring to the last decades, the application of these membranes as bio-mimetic sensor devices will be also reported.

  7. Electrosynthesis of molecularly imprinted polypyrrole for the antibiotic levofloxacin

    Energy Technology Data Exchange (ETDEWEB)

    Mazzotta, Elisabetta, E-mail: elisabetta.mazzotta@unisalento.it [Laboratorio di Chimica Analitica, Dipartimento di Scienza dei Materiali, Universita del Salento, via Monteroni 73100 Lecce (Italy); Malitesta, Cosimino [Laboratorio di Chimica Analitica, Dipartimento di Scienza dei Materiali, Universita del Salento, via Monteroni 73100 Lecce (Italy); Diaz-Alvarez, Myriam; Martin-Esteban, Antonio [Departamento de Medio Ambiente, INIA, Carretera de A Coruna km 7.5, 28240 Madrid (Spain)

    2012-01-01

    The development of an electrosynthesized imprinted polypyrrole (PPY) film onto a platinum sheet as sorbent phase for a fluoroquinolone antibiotic (levofloxacin) is described. Experimental conditions for the electropolymerization of PPY in the presence of the template were optimized. The molecularly imprinted polymer (MIP) film was characterized by X-Ray Photoelectron Spectroscopy (XPS) to verify the template entrapment in the polymeric matrix. After being subject to washing procedures, MIP was analyzed by XPS and a very satisfactory template removal was estimated being equal to 83%. The effectiveness of washing protocol was assessed also by UV-vis and High Performance Liquid Chromatography (HPLC) analysis of corresponding washing solutions. Rebinding experiments were performed by exposing the imprinted PPY film to levofloxacin solutions, subsequently analyzed by HPLC. The effect of solvent and time of exposure was investigated. The imprinting effect was verified by comparing recognition abilities of both MIP and not imprinted polymer (a polymer prepared in the same conditions but in the absence of the template).

  8. Polymer Catalysts Imprinted with Metal Ions as Biomimics of Metalloenzymes

    Directory of Open Access Journals (Sweden)

    Joanna Czulak

    2013-01-01

    Full Text Available This work presents the preparation and properties of molecularly imprinted polymers (MIPs with catalytic centers that mimic the active sites of metalloenzymes. The MIP synthesis was based on suspension polymerization of functional monomers (4-vinylpyridine and acrylonitrile with trimethylolpropane trimethacrylate as a crosslinker in the presence of transition metal ions and 4-methoxybenzyl alcohol as a template. Four metal ions have been chosen for imprinting from among the microelements that are the most essential in the native enzymes: Cu2+, Co2+, Mn2+, and Zn2+. To prepare catalysts, the required loading of metal ions was obtained during sorption process. The catalysts imprinted with Cu2+, Co2+, and Zn2+ were successfully used for hydroquinone oxidation in the presence of hydrogen peroxide. The Mn2+-imprinted catalyst showed no activity due to the insufficient metal loading. Cu2+ MIP showed the highest efficiency. In case of Cu- and Co-MIP catalysts, their activity was additionally increased by the use of surface imprinting technique.

  9. Cell Pluripotency Levels Associated with Imprinted Genes in Human

    Directory of Open Access Journals (Sweden)

    Liyun Yuan

    2015-01-01

    Full Text Available Pluripotent stem cells are exhibited similarly in the morphology, gene expression, growth properties, and epigenetic modification with embryonic stem cells (ESCs. However, it is still controversial that the pluripotency of induced pluripotent stem cell (iPSC is much inferior to ESC, and the differentiation capacity of iPSC and ESC can also be separated by transcriptome and epigenetics. miRNAs, which act in posttranscriptional regulation of gene expression and are involved in many basic cellular processes, may reveal the answer. In this paper, we focused on identifying the hidden relationship between miRNAs and imprinted genes in cell pluripotency. Total miRNA expression patterns in iPSC and ES cells were comprehensively analysed and linked with human imprinted genes, which show a global picture of their potential function in pluripotent level. A new CPA4-KLF14 region which locates in chromosomal homologous segments (CHSs within mammals and include both imprinted genes and significantly expressed miRNAs was first identified. Molecular network analysis showed genes interacted with imprinted genes closely and enriched in modules such as cancer, cell death and survival, and tumor morphology. This imprinted region may provide a new look for those who are interested in cell pluripotency of hiPSCs and hESCs.

  10. Cell Pluripotency Levels Associated with Imprinted Genes in Human.

    Science.gov (United States)

    Yuan, Liyun; Tang, Xiaoyan; Zhang, Binyan; Ding, Guohui

    2015-01-01

    Pluripotent stem cells are exhibited similarly in the morphology, gene expression, growth properties, and epigenetic modification with embryonic stem cells (ESCs). However, it is still controversial that the pluripotency of induced pluripotent stem cell (iPSC) is much inferior to ESC, and the differentiation capacity of iPSC and ESC can also be separated by transcriptome and epigenetics. miRNAs, which act in posttranscriptional regulation of gene expression and are involved in many basic cellular processes, may reveal the answer. In this paper, we focused on identifying the hidden relationship between miRNAs and imprinted genes in cell pluripotency. Total miRNA expression patterns in iPSC and ES cells were comprehensively analysed and linked with human imprinted genes, which show a global picture of their potential function in pluripotent level. A new CPA4-KLF14 region which locates in chromosomal homologous segments (CHSs) within mammals and include both imprinted genes and significantly expressed miRNAs was first identified. Molecular network analysis showed genes interacted with imprinted genes closely and enriched in modules such as cancer, cell death and survival, and tumor morphology. This imprinted region may provide a new look for those who are interested in cell pluripotency of hiPSCs and hESCs. PMID:26504487

  11. Chitosan in Molecularly-Imprinted Polymers: Current and Future Prospects.

    Science.gov (United States)

    Xu, Long; Huang, Yun-An; Zhu, Qiu-Jin; Ye, Chun

    2015-08-07

    Chitosan is widely used in molecular imprinting technology (MIT) as a functional monomer or supporting matrix because of its low cost and high contents of amino and hydroxyl functional groups. The various excellent properties of chitosan, which include nontoxicity, biodegradability, biocompatibility, and attractive physical and mechanical performances, make chitosan a promising alternative to conventional functional monomers. Recently, chitosan molecularly-imprinted polymers have gained considerable attention and showed significant potential in many fields, such as curbing environmental pollution, medicine, protein separation and identification, and chiral-compound separation. These extensive applications are due to the polymers' desired selectivity, physical robustness, and thermal stability, as well as their low cost and easy preparation. Cross-linkers, which fix the functional groups of chitosan around imprinted molecules, play an important role in chitosan molecularly-imprinted polymers. This review summarizes the important cross-linkers of chitosan molecularly-imprinted polymers and illustrates the cross-linking mechanism of chitosan and cross-linkers based on the two glucosamine units. Finally, some significant attempts to further develop the application of chitosan in MIT are proposed.

  12. Chitosan in Molecularly-Imprinted Polymers: Current and Future Prospects

    Directory of Open Access Journals (Sweden)

    Long Xu

    2015-08-01

    Full Text Available Chitosan is widely used in molecular imprinting technology (MIT as a functional monomer or supporting matrix because of its low cost and high contents of amino and hydroxyl functional groups. The various excellent properties of chitosan, which include nontoxicity, biodegradability, biocompatibility, and attractive physical and mechanical performances, make chitosan a promising alternative to conventional functional monomers. Recently, chitosan molecularly-imprinted polymers have gained considerable attention and showed significant potential in many fields, such as curbing environmental pollution, medicine, protein separation and identification, and chiral-compound separation. These extensive applications are due to the polymers’ desired selectivity, physical robustness, and thermal stability, as well as their low cost and easy preparation. Cross-linkers, which fix the functional groups of chitosan around imprinted molecules, play an important role in chitosan molecularly-imprinted polymers. This review summarizes the important cross-linkers of chitosan molecularly-imprinted polymers and illustrates the cross-linking mechanism of chitosan and cross-linkers based on the two glucosamine units. Finally, some significant attempts to further develop the application of chitosan in MIT are proposed.

  13. Quantum-dots-encoded-microbeads based molecularly imprinted polymer.

    Science.gov (United States)

    Liu, Yixi; Liu, Le; He, Yonghong; He, Qinghua; Ma, Hui

    2016-03-15

    Quantum dots encoded microbeads have various advantages such as large surface area, superb optical properties and the ability of multiplexing. Molecularly imprinted polymer that can mimic the natural recognition entities has high affinity and selectivity for the specific analyte. Here, the concept of utilizing the quantum dots encoded microbeads as the supporting material and the polydopamine as the functional monomer to form the core-shell molecular imprinted polymer was proposed for the first time. The resulted imprinted polymer can provide various merits: polymerization can complete in aqueous environment; fabrication procedure is facile and universal; the obvious economic advantage; the thickness of the imprinting layer is highly controllable; polydopamine coating can improve the biocompatibility of the quantum dot encoded microbeads. The rabbit IgG binding and flow cytometer experiment result showed the distinct advantages of this strategy: cost-saving, facile and fast preparation procedure. Most importantly, the ability for the multichannel detection, which makes the imprinted polydopamine modified encoded-beads very attractive in protein pre-concentration, recognition, separation and biosensing. PMID:26520251

  14. Genomic imprinting is variably lost during reprogramming of mouse iPS cells

    OpenAIRE

    Takikawa, Sachiko; Ray, Chelsea; Wang, Xin; Shamis, Yulia; Wu, Tien-Yuan; Li, Xiajun

    2013-01-01

    Derivation of induced pluripotent stem (iPS) cells is mainly an epigenetic reprogramming process. It is still quite controversial how genomic imprinting is reprogrammed in iPS cells. Thus, we derived multiple iPS clones from genetically identical mouse somatic cells. We found that parentally inherited imprint was variably lost among these iPS clones. Concurrent with the loss of DNA methylation imprint at the corresponding Snrpn and Peg3 imprinted regions, parental origin-specific expression o...

  15. The enemies of books

    CERN Document Server

    Blades, William

    2012-01-01

    A fascinating look at the myriad enemies of the printed book, from fire, to neglect, to children, to the bookworm, to plain old ignorance. A passionate litany against all who would see printed literature destroyed, written by English printer and bibliographer William Blades.

  16. Vietnam in Childrens' Books.

    Science.gov (United States)

    United Nations Children's Fund, New York, NY. United States Committee.

    Twenty-five nonfiction and 18 fiction and folklore listings are included in this bulletin on Vietnam in childrens' books. Slides, filmstrips, and film listings are also included. Each listing is accompanied by a brief annotation. Subjects include customs and culture, the country and the people, Ho Chi Min, the Vietnamese revolution, Vietnamese…

  17. Basic Drafting: Book Two.

    Science.gov (United States)

    Davis, Ronald; And Others

    The second of a two-book course in drafting, this manual consists of 12 topics in the following units: sketching techniques, geometric constructions, orthographic views, dimensioning procedures, basic tolerancing, auxiliary views, sectional views, inking tools and techniques, axonometrics, oblique, perspective, and computer-aided drafting.…

  18. Children & Books. Sixth Edition.

    Science.gov (United States)

    Sutherland, Zena; And Others

    Designed for classes in children's literature in English and education departments and in library schools, the emphases in this book are on understanding children and their needs, on perspectives and background, on criteria and types of literature, and on artists and authors. The first part provides an overview of children's needs and interests,…

  19. China resource book

    NARCIS (Netherlands)

    Trouwborst, K.O.; Eijndthoven, van P.J.

    1999-01-01

    The China Resource Book explains the organisation of the agricultural production in China and relates it to China's efforts to eradicate poverty and achieve self-sufficiency in food. It also highlights the variety of environmental problems, which haverisen since the rapid industrial development in t

  20. Generalizability Theory [Book Review].

    Science.gov (United States)

    Kane, Michael

    2003-01-01

    This book presents a comprehensive overview of univariate and multivariate generalizability theory, a psychometric model that provides a powerful approach to the analysis of errors of measurement through the use of random-effects and mixed-model analysis of variance. (SLD)

  1. The Ultimate Toilet Book

    Institute of Scientific and Technical Information of China (English)

    MINA CHOI

    2008-01-01

    @@ What happens to the feces that you flush down the toilet? Rose George, a journalist who used to write for British newspapers The Guardian and The Independent, has traveled all over the world to uncover the mystery of the world's sanitation systems and to map the terrain of "shit," which she consistently refers to using this coarse expression throughout the book.

  2. Basic Drafting: Book One.

    Science.gov (United States)

    Davis, Ronald; And Others

    The first of a two-book course in drafting, this manual consists of 13 topics in the following units: introduction to drafting, general safety, basic tools and lines, major equipment, applying for a job, media, lettering, reproduction, drawing sheet layout, architect's scale usage, civil engineer's scale usage, mechanical engineer's scale usage,…

  3. BOOK REVIEWS - Precision agriculture

    Directory of Open Access Journals (Sweden)

    Stanisław Samborski

    2007-01-01

    Full Text Available Precision agriculture (PA is a term, which has recently become very popular in agronomy. In short this term means crop production based on site-specific crop management (SSCM. Precision agriculture is an integrated agricultural management system incorporating different science disciplines e.g. crop science, agricultural engineering and geostatistics. It also uses numerous tools i.e., geographic information system (GIS, Global Positioning System (GPS, remote sensing yield monitors. Because of the multidisciplinary character of precision agriculture, books published on this subject differ in their content. The first books on this topic appeared in the mid 90’ of the last century. The intention of this paper is to present reviews of three books the titles of which each contains the term “precision agriculture”. The books are as follows:1 Handbook of Precision Agriculture – Principles and Applications (2006 edited by Ancha Srinivasan. 2 Precision Agriculture’05 (2005 edited by John V. Stafford 3 Precision Agriculture (2006 by Terry A. Brasse.

  4. Books, Biodiversity, and Beyond!

    Science.gov (United States)

    Governor, Donna; Helms, Sarah

    2007-01-01

    Reading in science class does not have to be boring, but it is no secret to students or teachers that textbooks are not much fun to read. It is always a challenge for teachers to find reading materials that would grab the interests of their students. In this article, the author relates how she used Biodiversity, a nonfiction book by Dorothy…

  5. CMS Comic Book Brochure

    CERN Document Server

    2006-01-01

    To raise students' awareness of what the CMS detector is, how it was constructed and what it hopes to find. Titled "CMS Particle Hunter," this colorful comic book style brochure explains to young budding scientists and science enthusiasts in colorful animation how the CMS detector was made, its main parts, and what scientists hope to find using this complex tool.

  6. The Comic Book Project

    Science.gov (United States)

    Bitz, Michael

    2008-01-01

    The Comic Book Project (CBP) celebrates its eighth anniversary this year. The project, which just originated with one school in New York City, had grown to encompass thousands of students nationwide. The goal of the CBP is not to create comics the "Marvel way" or to develop the next Stan Lee. Rather, the goal is to give students the opportunity to…

  7. Book Your Summer Vacation

    Science.gov (United States)

    Texley, Juliana

    2012-01-01

    Summer's the time for teachers to travel, not only physically from the confines of the classroom to exotic places, but vicariously, through the magic of books. Summer adventures help teachers expand their experience and enrich their store of context so that they can offer their students more when school resumes in the fall. That's why each year…

  8. Book on CPC Published

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A book that answers 13 questions about how the Communist Party of China(CPC) works in China and why the Party has made great achievements in the past decades has been recently published by the Beijing-based New World Press.

  9. Making a Memory Book

    Medline Plus

    Full Text Available Narrator: Another project you and your loved one can do together is make a memory book. Hattie Grossman is 93 years ... grandchildren. This afternoon they're working on a project with University of Pittsburgh researcher, Michelle Bourgeois. Bourgeois: ...

  10. Books Behind Bars.

    Science.gov (United States)

    Gulker, Virgil

    This book reports on an experiment in literacy which was carried out at the federal correctional institution in Milan, Michigan. Contents include: an introduction by Daniel N. Fader, "Walden's Bookshop," a discussion of a prison library; "The Milan Library: A History of Inmate Involvement"; "Literature and the Clientele," a discussion of inmate…

  11. Spoken Russian; Book Two.

    Science.gov (United States)

    Bloomfield, Leonard; Petrova, Luba

    This course in spoken Russian is intended for use in introductory conversational classes. Book II in the two volume series is divided into three major parts, each containing five learning units and one unit devoted to review. Each unit contains sections including (1) basic sentences, (2) word study and review of basic sentences, (3) listening…

  12. BOOK REVIEW: Supergravity Supergravity

    Science.gov (United States)

    Gregory, Ruth

    2013-02-01

    Supergravity is an essential ingredient in so many areas of ultra high energy physics, yet it is rarely taught systematically, even at the graduate level. Students most often have to learn along with applying, and must use the now classic older texts. For such core material, it is surprising that there are so few good texts on the subject. It is not necessarily that supergravity is so much more conceptually complex, rather that it is technical and therefore easy for a text to become dry, dense and rather indigestible. This book, written by two experts in the field, is therefore a breath of fresh air. It not only represents a comprehensive modern overview of the subject, but achieves this with clarity, accessibility, and even humour! To paraphrase the authors, if you are not impressed by this book, you should put it down and watch television instead. It starts by reviewing, or overviewing, aspects of field theory, basic supersymmetry and gravity that will be needed for the rest of the book. This first third or so of the book is very condensed, and will not be easy to follow for those who have not encountered the material before. However, the authors acknowledge this and give plenty of suggestions for more pedagogical texts in the relevant areas, thus it does not feel overly brief. The middle section deals with the construction of supergravity, starting with basic N = 1 supergravity in 4 and 11 dimensions and gradually extending the discussion to include matter multiplets. This part of the book systematically builds up understanding and construction of models, before moving on to superconformal methods. The purpose is not to cover all supergravity theories, but to focus on a few examples in detail, and to give sufficient expertise and information for the reader to be able to deal with any other models they might need. The final part of the book deals with applications, and includes two chapters on applications in adS/CFT, which will be of most interest to new

  13. Human imprinting anomalies in fetal and childhood growth disorders: clinical implications and molecular mechanisms.

    Science.gov (United States)

    Azzi, Salah; Brioude, Fréderic; Le Bouc, Yves; Netchine, Irène

    2014-01-01

    Genomic imprinting is among the most important epigenetic mechanisms whereby expression of a subset of genes is restricted to a single parental allele. Loss of imprinting (LOI) through hypo or hyper methylation is involved in various human syndromes. These LOI occur early during development and usually impair growth. Some imprinting syndromes are the consequences of genetic anomalies, such as uniparental disomies (UPD) or copy number variations (deletion or duplications) involving the imprinted domains; others are due to LOI at the imprinting control regions (ICR) regulating each domain. Imprinting disorders are phenotypically heterogeneous, although some share various common clinical features such that diagnosis may be difficult. Multilocus imprinting defects associated with several syndromes have been increasingly reported in recent years, although there are no obvious clinical differences between monolocus and multilocus LOI patients. Subsequently, some rare mutations of transacting factors have been identified in patients with multilocus imprinting defects but they do not explain the majority of the cases; this therefore implies that other factors are involved. By contrast, no mutation of a transacting factor has yet been identified in monolocus LOI. The effect of the environment on the regulation of imprinting is clearly illustrated by studies of assisted reproductive technology (ART). The regulation of imprinting is complex and involves a huge range of genetic and environmental factors; the identification of these factors will undoubtedly help to elucidate the regulation of imprinting and contribute to the understanding of imprinting disorders. This would be beneficial for diagnostics, clinical follow up and the development of treatment guidelines. PMID:23888961

  14. Synthesis of Molecularly Imprinted Polymer Particles by Suspension Polymerization in Silicon Oil

    Institute of Scientific and Technical Information of China (English)

    Xiao Bing WANG; Zhao Hui ZHENG; Xiao Bin DING; Xu CHENG; Xin Hua HU; Yu Xing PENG

    2006-01-01

    Molecularly imprinted polymers using 2,4-dichlorophenoxyacetic acid (2,4-D) as templates were prepared by suspension polymerization in silicon oil. The polymer particles exhibited regular shape in the micro-scale range. The adsorbing experiments indicated that the imprinted polymer particles possessed higher affinity to 2,4-D than the non-imprinted polymer particles.

  15. Modular Polymer Biosensors by Solvent Immersion Imprint Lithography

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Jayven S.; Xantheas, Sotiris S.; Grate, Jay W.; Wietsma, Thomas W.; Gratton, Enrico; Vasdekis, Andreas

    2016-01-01

    We recently demonstrated Solvent Immersion Imprint Lithography (SIIL), a rapid benchtop microsystem prototyping technique, including polymer functionalization, imprinting and bonding. Here, we focus on the realization of planar polymer sensors using SIIL through simple solvent immersion without imprinting. We describe SIIL’s impregnation characteristics, including an inherent mechanism that not only achieves practical doping concentrations, but their unexpected 4-fold enhancement compared to the immersion solution. Subsequently, we developed and characterized optical sensors for detecting molecular O2. To this end, a high dynamic range is reported, including its control through the immersion duration, a manifestation of SIIL’s modularity. Overall, SIIL exhibits the potential of improving the operating characteristics of polymer sensors, while significantly accelerating their prototyping, as it requires a few seconds of processing and no need for substrates or dedicated instrumentation. These are critical for O2 sensing as probed by way of example here, as well as any polymer permeable reactant.

  16. A role for chromatin topology in imprinted domain regulation.

    Science.gov (United States)

    MacDonald, William A; Sachani, Saqib S; White, Carlee R; Mann, Mellissa R W

    2016-02-01

    Recently, many advancements in genome-wide chromatin topology and nuclear architecture have unveiled the complex and hidden world of the nucleus, where chromatin is organized into discrete neighbourhoods with coordinated gene expression. This includes the active and inactive X chromosomes. Using X chromosome inactivation as a working model, we utilized publicly available datasets together with a literature review to gain insight into topologically associated domains, lamin-associated domains, nucleolar-associating domains, scaffold/matrix attachment regions, and nucleoporin-associated chromatin and their role in regulating monoallelic expression. Furthermore, we comprehensively review for the first time the role of chromatin topology and nuclear architecture in the regulation of genomic imprinting. We propose that chromatin topology and nuclear architecture are important regulatory mechanisms for directing gene expression within imprinted domains. Furthermore, we predict that dynamic changes in chromatin topology and nuclear architecture play roles in tissue-specific imprint domain regulation during early development and differentiation.

  17. THE MEANING OF GENOMIC IMPRINTING IN HUMAN GENETIC AND DEFECTOLOGY

    Directory of Open Access Journals (Sweden)

    Anastas LAKOSKI

    2000-12-01

    Full Text Available Several genetic phenomena do not appear to conform the Mendel's low in the sense that they are not inherited in simple way through the generations. Such exceptions to Mendel's laws include new mutations, changes in chromosomes, expanded triplet sequences, and genomic imprinting. Many genetic diseases involve spontaneous mutations that are not inherited from generation to generation. Changes in chromosomes include nondisjunction, which is the most important cause of mental retardation, the trisomy of Dowen syndrome. Expanded triplet repeats are responsible for the next important cause of mental retardation, fragile X, and for Huntington's disease. Genomic imprinting occurs when the expression of a gene depends on whether it is inherited from the mother or from the father. In this paper the phenomenon of genomic imprinting is explained on the occurrence of Angelman and Prader-Willi syndromes. It's essential for the counselor to be able during the genetic counseling to recognize this phenomenon and to make a proper decision.

  18. GENE IMPRINTING: ENGRAVING THE PATHOGENESIS OF HERIDETARY DISEASES

    Directory of Open Access Journals (Sweden)

    Sandeep Satapathy

    2014-01-01

    Full Text Available Gene imprinting has conduited the scope of our understanding of phenotypic expression and its corelation with constituent genotype. It is an epigenetic process that involves DNA methylation and histone modulation to attain monoallelic gene expression without altering the genetic sequences. A distinctive model of non-mendelian genetics, imprinting extends the control over expression of traits and selection of the allele that would direct the same, in a manner decided by the parent of origin. The constitutive existence of this imprinting even after gametogenesis, throughout the somatic development extends a clue for its regulatory hold on several heridetary traits. Several heridetary diseases like Cancers, Russell-Silver syndrome, Beckwith-Wiedemann syndrome, Prader-Willi and Angelman Syndromes and Neurodegenration have shown to be a subsequent error in the genomic impriting process. So, understanding these epigenetic regulations can be a therapeutic strategy for disease modelling and especially targeting their patterns of heridetary inheritance.

  19. Book Review: 3 Titles from A Book Apart

    Directory of Open Access Journals (Sweden)

    Nathan Mealey

    2011-07-01

    Full Text Available Three recently published books by A Book Apart, the book-publishing arm of the website A List Apart, offer concise, high-impact introductions to three tools that can be employed in facing this challenge: HTML5, CSS3, and content strategy. This article reviews the books "HTML5 For Web Designers" by Jeremy Keith; "CSS3 for Web Designers" by Dan Cederholm; and "The Elements of Content Strategy" by Erin Kissane.

  20. 32 nm imprint masks using variable shape beam pattern generators

    Science.gov (United States)

    Selinidis, Kosta; Thompson, Ecron; Schmid, Gerard; Stacey, Nick; Perez, Joseph; Maltabes, John; Resnick, Douglas J.; Yeo, Jeongho; Kim, Hoyeon; Eynon, Ben

    2008-05-01

    Imprint lithography has been included on the ITRS Lithography Roadmap at the 32, 22 and 16 nm nodes. Step and Flash Imprint Lithography (S-FIL ®) is a unique method that has been designed from the beginning to enable precise overlay for creating multilevel devices. A photocurable low viscosity monomer is dispensed dropwise to meet the pattern density requirements of the device, thus enabling imprint patterning with a uniform residual layer across a field and across entire wafers. Further, S-FIL provides sub-100 nm feature resolution without the significant expense of multi-element, high quality projection optics or advanced illumination sources. However, since the technology is 1X, it is critical to address the infrastructure associated with the fabrication of templates. For sub-32 nm device manufacturing, one of the major technical challenges remains the fabrication of full-field 1x templates with commercially viable write times. Recent progress in the writing of sub-40 nm patterns using commercial variable shape e-beam tools and non-chemically amplified resists has demonstrated a very promising route to realizing these objectives, and in doing so, has considerably strengthened imprint lithography as a competitive manufacturing technology for the sub 32nm node. Here we report the first imprinting results from sub-40 nm full-field patterns, using Samsung's current flash memory production device design. The fabrication of the template is discussed and the resulting critical dimension control and uniformity are discussed, along with image placement results. The imprinting results are described in terms of CD uniformity, etch results, and overlay.

  1. From the Popcorn Book to Popcorn!: Multigenre Children's Books

    Science.gov (United States)

    Danielson, Kathy Everts; Harrington, Jeanne

    2005-01-01

    Multigenre texts are a recent trend in children's books. These types of books can enhance students' comprehension and provide models of various types of writing genres. They can be used in differentiating instruction and increasing fluency when transformed into readers' theater texts. Many examples of multigenre books are provided in this article.

  2. Advancements of molecularly imprinted polymers in the food safety field.

    Science.gov (United States)

    Wang, Peilong; Sun, Xiaohua; Su, Xiaoou; Wang, Tie

    2016-06-01

    Molecularly imprinted technology (MIT) has been widely employed to produce stable, robust and cheap molecularly imprinted polymer (MIP) materials that possess selective binding sites for recognition of target analytes in food, such as pesticides, veterinary drugs, mycotoxins, illegal drugs and so on. Because of high selectivity and specificity, MIPs have drawn great attention in the food safety field. In this review, the recent developments of MIPs in various applications for food safety, including sample preparation, chromatographic separation, sensing, immunoassay etc., have been summarized. We particularly discuss the advancements and limitations in these applications, as well as attempts carried out for their improvement. PMID:26937495

  3. The Burden of the Book

    DEFF Research Database (Denmark)

    Damkjær, Maria

    2012-01-01

    Review of Leah Price, How to Do Things with Books in Victorian Britain (Princeton University Press, 2012)......Review of Leah Price, How to Do Things with Books in Victorian Britain (Princeton University Press, 2012)...

  4. Moving from Books to Bytes.

    Science.gov (United States)

    Albanese, Andrew Richard

    2001-01-01

    This academic library book buying survey examines full-text databases; electronic journals; top circulating subjects; price increases for serials and resulting subscription cuts; the influence of digital choices on purchasing decisions; circulation versus use statistics; and electronic books. (LRW)

  5. TM4Book: Visualization transforms

    DEFF Research Database (Denmark)

    2011-01-01

    XSLT-scripts til visualisering af semantiske strukturer i teksteditoren TM4Book: plot, storyline og timeline......XSLT-scripts til visualisering af semantiske strukturer i teksteditoren TM4Book: plot, storyline og timeline...

  6. Interactivite content of electronic books

    OpenAIRE

    Gorbatiuc, Julia

    2013-01-01

    This thesis Interactive content of eBooks presents complex view on preparations and development of interactive and enhanced electronic book from technical, legislative, content and economic perspective. It describes types of interactivity modules, available interactive eBook formats, reading devices and software. It also compares USA market to the Czech market of interactive eBooks. This thesis processes results of questionnaire survey in the area of Czech readers awareness of interactive eBo...

  7. Engineering mathematics pocket book

    CERN Document Server

    Bird, John

    2008-01-01

    This compendium of essential formulae, definitions, tables and general information provides the mathematical information required by students, technicians, scientists and engineers in day-to-day engineering practice. A practical and versatile reference source, now in its fourth edition, the layout has been changed and the book has been streamlined to ensure the information is even more quickly and readily available - making it a handy companion on-site, in the office as well as for academic study. It also acts as a practical revision guide for those undertaking BTEC Nationals, Higher Nationals and NVQs, where engineering mathematics is an underpinning requirement of the course.All the essentials of engineering mathematics - from algebra, geometry and trigonometry to logic circuits, differential equations and probability - are covered, with clear and succinct explanations and illustrated with over 300 line drawings and 500 worked examples based in real-world application. The emphasis throughout the book is on ...

  8. SURFACE METAL ION-IMPRINTED RESINS PREPARED BY EMULSIFIER-FREE EMULSION POLYMERIZATION USING PHOSPHORIC DIESTER AS FUNCTIONAL MONOMER

    Institute of Scientific and Technical Information of China (English)

    GUO Tianying; ZHANG Liying; HAO Guangjie; SONG Muodao; ZHANG Banghua

    2003-01-01

    The uniform surface ion-imprinted resins for Zn2+ as the imprinting guest were prepared by emulsi fier-free emulsion polymerization utilizing ally phenyl hydrogenphosphate as a functional comonomer. The Zn2+-imprinted resin adsorbed Zn2+ much more effectively than did the unimprinted one. The selective feature of the surface imprinted resins to the template ions was demonstrated.

  9. The Chinese in Children's Books.

    Science.gov (United States)

    New York Public Library, NY.

    This is a selective annotated list of children's books about China and the Chinese. Topics range from dynasties, the era of Western influence, emigration, revolution, to present day affairs. Most of the books have a Chinese setting, but some are about the Chinese in America. Listings are made under categories such as picture books, stories for…

  10. The Real E-books.

    Science.gov (United States)

    Ditlea, Steve

    2000-01-01

    Focuses on the "real" e-books. Discusses Stephen King's novella released exclusively for electronic publication, and discusses experiences of another author writing on a specialized subject. Presents a brief background of e-books. Examines the differences between Portable Document Format (PDF) technology and the new Open eBook (OEB) standard.…

  11. Book History and Ideological Hierarchies

    Science.gov (United States)

    Dilevko, Juris; Dali, Keren

    2006-01-01

    The evolving field of Book History has had difficulty in integrating the experiences of immigrant culture. In explaining the origins of print culture in North America, Book History has a tendency to associate lowbrow with immigrants and their struggles to establish a foothold in a new land. Book History therefore symbolically defines immigrant…

  12. Construction Management : Study Book

    OpenAIRE

    Ilveskoski, Olli; Niittymäki, Seppo

    2015-01-01

    This publication is a summary of the Construction Management course handscript. The objective is that as the students gets involved with the Construction Management of Building Projects they will learn Construction Management topics like Building Process, Production planning, Quantity Take Off, Cost Estimation, Scheduling, Work Safety and Quality Control. The study book has been in use in Construction Management courses in Häme University of Applied Sciences.

  13. Level up Book Club

    Science.gov (United States)

    LaGarde, Jennifer; Winner, Matthew C.

    2012-01-01

    Like all great ideas, Level Up Book Club grew out of a genuine need, the spontaneous firing of a few brain sparks, and the kind of luck that comes from being "in the right place at the right time." By mid-June 2011 the authors were already "bona fide" wonder twins--two educators who, although they'd never met, had stumbled upon each other through…

  14. Book review: Urban China

    OpenAIRE

    Koh, Sin Yee

    2013-01-01

    "Urban China." Xuefei Ren. Polity. March 2013. --- Currently there are more than 125 Chinese cities with a population exceeding one million. The unprecedented urban growth in China presents a crucial development for studies on globalization and urban transformation. This book examines the past trajectories, present conditions, and future prospects of Chinese urbanization, by investigating five key themes – governance, migration, landscape, inequality, and cultural economy. Sin Yee Koh fin...

  15. Electronic books and journals

    OpenAIRE

    Endres, A.

    1996-01-01

    Electronic books and journals are both desirable and feasible. From a user's point of view they solve some shortcomings of conventional media, but more important are the new opportunities they open. To exploit those, a number of technical challenges have to be addressed. Besides, a series of business and organisational issues have to be taken care of. The German project MeDoc had to cope with a subset of these questions and found pragmatic answers. Libraries and librarians are well adviced to...

  16. Book review: Congo

    OpenAIRE

    Krupa, Joel

    2013-01-01

    "Congo." Thomas Turner. Polity. April 2013. --- The Democratic Republic of Congo has become one of the world’s bloodiest hot spots, and despite recent peace agreements and democratic elections, the country is still plagued by army and militia violence. Thomas Turner‘s insightful book discusses how the the deep–rooted causes of conflict have not been adequately addressed, and shows how current attempts to rebuild the shattered state and society of DRC are doomed to fail. Joel Krupa recomme...

  17. The Delights of Books

    Institute of Scientific and Technical Information of China (English)

    徐保国

    2005-01-01

    Books are to mankind what memory is to the individual.They contain the history of our race,the discoveries we have made,the accumulated knowledge and experience of ages;they picture for us the marvels and beauties of nature,help us in our difficulties, comfort us in sorrow and in suffering,change hours of weariness into moments of delight,store our minds with ideas,

  18. Pi a source book

    CERN Document Server

    Berggren, Lennart; Borwein, Peter

    2004-01-01

    This book documents the history of pi from the dawn of mathematical time to the present. One of the beauties of the literature on pi is that it allows for the inclusion of very modern, yet accessible, mathematics. The articles on pi collected herein include selections from the mathematical and computational literature over four millennia, a variety of historical studies on the cultural significance of the number, and an assortment of anecdotal, fanciful, and simply amusing pieces. For this new edition, the authors have updated the original material while adding new material of historical and cultural interest. There is a substantial exposition of the recent history of the computation of digits of pi, a discussion of the normality of the distribution of the digits, new translations of works by Viete and Huygen, as well as Kaplansky's never-before-published "Song of Pi." From the reviews of earlier editions: "Few mathematics books serve a wider potential readership than does a source book and this particular on...

  19. The Wellcome Prize Lecture. Genetic imprinting: the battle of the sexes rages on.

    Science.gov (United States)

    Reik, W

    1996-03-01

    Genomic imprinting in mammals is an important genetic mechanism by which genes are expressed or repressed depending on which parent they have been inherited from. Some properties of the imprinting mechanism are already established; notably, some of the effects of imprinting on mammalian development can be explained by the phenotypic effects of a number of specific imprinted genes, which include major fetal growth factors. An evolutionary explanation of imprinting has also been suggested. Some of the molecular mechanisms of imprinting are known, and these include the modification of DNA and chromosomes in the form of DNA methylation and possibly heritable chromatin structures. Loss of imprinting or altered imprinting is implicated in a large number of genetic diseases and cancers. Many important issues remain to be resolved; these include the precise molecular mechanisms and, in particular, the nature of the primary imprints that are inherited from the parental gametes, and the genes that control the imprinting process. Isolation of the majority of imprinted genes and the elucidation of their phenotypic effects and physiology are major goals for the future. These studies will provide important insights into human genetics, and will connect evolutionary understanding with physiology, genetic disease and human behaviour. PMID:8845132

  20. The Wellcome Prize Lecture. Genetic imprinting: the battle of the sexes rages on.

    Science.gov (United States)

    Reik, W

    1996-03-01

    Genomic imprinting in mammals is an important genetic mechanism by which genes are expressed or repressed depending on which parent they have been inherited from. Some properties of the imprinting mechanism are already established; notably, some of the effects of imprinting on mammalian development can be explained by the phenotypic effects of a number of specific imprinted genes, which include major fetal growth factors. An evolutionary explanation of imprinting has also been suggested. Some of the molecular mechanisms of imprinting are known, and these include the modification of DNA and chromosomes in the form of DNA methylation and possibly heritable chromatin structures. Loss of imprinting or altered imprinting is implicated in a large number of genetic diseases and cancers. Many important issues remain to be resolved; these include the precise molecular mechanisms and, in particular, the nature of the primary imprints that are inherited from the parental gametes, and the genes that control the imprinting process. Isolation of the majority of imprinted genes and the elucidation of their phenotypic effects and physiology are major goals for the future. These studies will provide important insights into human genetics, and will connect evolutionary understanding with physiology, genetic disease and human behaviour.

  1. Imprinting in plants as a mechanism to generate seed phenotypic diversity

    Directory of Open Access Journals (Sweden)

    A Mark eSettles

    2015-01-01

    Full Text Available Normal plant development requires epigenetic regulation to enforce changes in developmental fate. Genomic imprinting is a type of epigenetic regulation in which identical alleles of genes are expressed in a parent-of-origin dependent manner. Deep sequencing of transcriptomes has identified hundreds of imprinted genes with scarce evidence for the developmental importance of individual imprinted loci. Imprinting is regulated through global DNA demethylation in the central cell prior to fertilization and directed repression of individual loci with the Polycomb Repressive Complex 2 (PRC2. There is significant evidence for transposable elements and repeat sequences near genes acting as cis-elements to determine imprinting status of a gene, implying that imprinted gene expression patterns may evolve randomly and at high frequency. Detailed genetic analysis of a few imprinted loci suggests an imprinted pattern of gene expression is often dispensable for seed development. Few genes show conserved imprinted expression within or between plant species. These data are not fully explained by current models for the evolution of imprinting in plant seeds. We suggest that imprinting may have evolved to provide a mechanism for rapid neofunctionalization of genes during seed development to increase phenotypic diversity of seeds.

  2. Preparation and recognition of surface molecularly imprinted core-shell microbeads for protein in aqueous solutions

    International Nuclear Information System (INIS)

    In this paper, a surface molecular imprinting technique was reported for preparing core-shell microbeads of protein imprinting, and bovine hemoglobin or bovine serum albumin were used as model proteins for studying the imprinted core-shell microbeads. 3-Aminophenylboronic acid (APBA) was polymerized onto the surface of polystyrene microbead in the presence of the protein templates to create protein-imprinted core-shell microbeads. The various samples were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and Brunauer-Emmett-Teller (BET) methods. The effect of pH on rebinding of the template hemoglobin, the specific binding and selective recognition were studied for the imprinted microbeads. The results show that the bovine hemoglobin-imprinted core-shell microbeads were successfully created. The shell was a sort of imprinted thin films with porous structure and larger surface areas. The imprinted microbeads have good selectivity for templates and high stability. Due to the recognition sites locating at or closing to the surface, these imprinted microbeads have good property of mass-transport. Unfortunately, the imprint technology was not successfully applied to imprinting bovine serum albumin (BSA).

  3. BOOK REVIEW: Complete Physics

    Science.gov (United States)

    Carson, Simon

    2000-03-01

    This book contains all the essential concepts for GCSE (or equivalent) physics courses or for general science courses at Key Stage 4. It claims to be ideal for use as a bridging resource for those intending to take physics beyond GCSE: it is no surprise, then, that the book is written at a level above that of the average Key Stage 4 student. It includes material not included in many GCSE syllabuses; this is clearly identified in the contents pages. It would be a useful resource for more able students at GCSE or for beginning A-level students. The layout of the book is attractive. It is well illustrated and colourful. Some of the illustrations are striking: each of the 12 main sections of the book begins with a title page that includes some unusual photographs illustrating physical ideas. Section 2, Forces and Motion, has a photograph of a bungee jumper leaping from the Sky Tower in New Zealand, taken at night looking along the length of the tower from its foot. Section 9, Magnets and Currents, has a computer-generated picture of the magnetic field in a fusion generator. These pictures, as well as contributing to the attractiveness of the book, could be used to initiate discussions of some of the physics. However, there are pictures that serve little useful purpose: a photograph of a recording station for seismic waves looks like any other building lit up at night. A photograph of a rock band in the middle of a section on sound carries no explanatory caption at all and is purely decorative. Other illustrations - in a variety of styles - do illustrate some physical ideas very well: the diagrams of motors and generators, for instance, are far clearer than my efforts on the blackboard! The book is divided into 14 sections with titles reflecting the traditional divisions of physics syllabuses, together with a beginning section on measurement and units and two final sections, `History of Key Ideas' and `Experimental Physics'. The first section, `Measurement and Units

  4. Shape recognition of microbial cells by colloidal cell imprints

    NARCIS (Netherlands)

    Borovicka, J.; Stoyanov, S.D.; Paunov, V.N.

    2013-01-01

    We have engineered a class of colloids which can recognize the shape and size of targeted microbial cells and selectively bind to their surfaces. These imprinted colloid particles, which we called "colloid antibodies", were fabricated by partial fragmentation of silica shells obtained by templating

  5. Different Imprinting Status of IGF-2 in Epithelial Ovarian Tumors

    Institute of Scientific and Technical Information of China (English)

    熊雅丽; 孙永玉; 李红发

    2002-01-01

    Summary: To explore whether the imprinting status of IGF-2 in the malignant epithelial ovarian tumors is different from that in benign tumors, the target sequences (DNA and RNA) which contain a polymorphism site for ApaI restriction endonuclease digestion were amplified with PCR and RT-PCR methods. Then the PCR/RT-PCR products were digested by ApaI. The IGF-2 transcriptional pattern came out from the results of endonucleases digestion. Among the 36 cases of benign epithelial ovarian tumors, 20 were heterozygous for ApaI locus and all showed genomic imprinting. While in the malignant group, 22 were heterozygous for ApaI locus but six were found to lose imprinting. Significant differences existed between the two groups (P<0. 05). Loss of imprinting of IGF-2 may serve as a marker for differentiating the malignant ovarian cancers from the benign ones. In a new field of molecular genetics, our research provides an experimental basis for genetic diagnosis and treatment of the ovarian cancers.

  6. Preparation and Property Recognition of Nimodipine Molecularly Imprinted Polymer

    Institute of Scientific and Technical Information of China (English)

    CHEN Fei-fei

    2015-01-01

    Objective:To explore the application of molecular imprinting technique in the separation and detection of nimodipine. Methods:Methacrylic acid as functional monomer, pentaerythritol triacrylate as cross-linking agent were used to prepare molecularly imprinted polymer (MIP) with the feature of specific recognition performance on imprinting molecule nimodipine under condition of template molecule nimodipine. The preparation conditions, recognition performance of MIP on nimodipine, different proportions of template molecule and functional monomer, the selectivity to other substrate, and the relationship between adsorption quantity (Q) and time were observed. Results: MIP was prepared successfully by nimodipine as template and pentaerythritol triacrylate as cross-linking agent, with the feature of speciifc recognition performance on nimodipine. The static adsorption distribution coefifcient (KD) was 0.2264. The equation of Q and the concentration of substrate of template MIP was y = -0.21x+0.2204. Combining capacity of template molecule at the same concentration enhanced with the increasing proportion of functional monomer. Conclusion:Nimodipine MIP based on molecular imprinting technique may become a new approach to chiral separation for nimodipine.

  7. Biologically inspired omniphobic surfaces by reverse imprint lithography.

    Science.gov (United States)

    Hensel, René; Finn, Andreas; Helbig, Ralf; Braun, Hans-Georg; Neinhuis, Christoph; Fischer, Wolf-Joachim; Werner, Carsten

    2014-04-01

    Springtail skin morphology is translated into robust omniphobic polymer membranes by reverse imprint lithography. The combination of overhanging cross-sections and their arrangement in a self-supporting comblike pattern are crucial for mechanically stable coatings that can be even applied to curved surfaces. PMID:24375518

  8. Preparation and Property Recognition of Nimodipine Molecularly Imprinted Polymer

    Directory of Open Access Journals (Sweden)

    Fei-fei CHEN

    2015-09-01

    Full Text Available Objective: To explore the application of molecular imprinting technique in the separation and detection of nimodipine. Methods: Methacrylic acid as functional monomer, pentaerythritol triacrylate as cross-linking agent were used to prepare molecularly imprinted polymer (MIP with the feature of specific recognition performance on imprinting molecule nimodipine under condition of template molecule nimodipine. The preparation conditions, recognition performance of MIP on nimodipine, different proportions of template molecule and functional monomer, the selectivity to other substrate, and the relationship between adsorption quantity (Q and time were observed. Results: MIP was prepared successfully bynimodipine as template and pentaerythritol triacrylate as cross-linking agent, with the feature of specific recognition performance on nimodipine. The static adsorption distribution coefficient (KD was 0.2264. The equation of Q and the concentration of substrate of template MIP was y = -0.21x+0.2204. Combining capacity of template molecule at the same concentration enhanced with the increasing proportion of functional monomer.Conclusion: Nimodipine MIP based on molecular imprinting technique may become a new approach to chiral separation for nimodipine.

  9. Polymer Stamps for Imprinting Nanopatterns in Polymer Substrate.

    Science.gov (United States)

    Wu, Jiahao; Amirsadeghi, Alborz; Kim, Jinsoo; Park, Sunggook

    2015-01-01

    Using a silicone or metallic stamp for imprinting multiscale patterns comprising micro down to nanoscale patterns into polymer substrates often results in significant deformation in the molded substrate and loss of pattern transfer fidelity for nanopatterns. In the worst case, the expensive stamp can also be damaged. One method to reduce the problem is to use polymer as the stamp material, which will reduce both adhesion and thermal stress generated at the stamp/substrate interface. In this paper, stamps made of three different polymer materials, i.e., polydimethylsiloxane (PDMS), PPGDA-based UV resin and TPGDA-based UV-resin, were fabricated from the same master containing nanofluidic structures and the replication fidelity from the master, polymer stamps, to thermal-imprinted poly(methyl methacrylate) substrate (PMMA) was compared. The largest loss of pattern fidelity occurs in the thermal imprinting step. Polymer stamps with higher Young's moduli result in a better fidelity in pattern transfer. With TPGDA-based UV resin stamps, multiscale structures with a nanochannel with minimum width and height of -70 nm can be imprinted onto PMMA substrate together with macro-scale patterns by a single nanoimprinting processes. PMID:26328384

  10. Prenatal imprinting by environmental toxicants: really an important issue?

    Directory of Open Access Journals (Sweden)

    Karl Ernst v. Mühlendahl

    2015-06-01

    Full Text Available Prenatal imprinting of sexual behaviour and of other traits by environmental toxicants has been one important topic in the ongoing discussions in environmental medicine. This review of the literature shows that, so far, concrete data are sparse and, in part, contradictory.

  11. SEXUAL IMPRINTING AND SONG LEARNING - 2 OF ONE KIND

    NARCIS (Netherlands)

    TENCATE, C; VOS, DR; MANN, N

    1993-01-01

    Imprinting and song learning in birds are usually categorized under the same heading as 'exposure', 'template' or 'programmed' learning. These terms point to several similarities between the processes, but exactly how similar they are and whether the similarity implies a direct causal linkage is not

  12. 3D Simulation of Nano-Imprint Lithography

    DEFF Research Database (Denmark)

    Román Marín, José Manuel; Rasmussen, Henrik K.; Hassager, Ole

    2010-01-01

    A proof of concept study of the feasibility of fully three-dimensional (3D) time-dependent simulation of nano-imprint lithography of polymer melt, where the polymer is treated as a structured liquid, has been presented. Considering the flow physics of the polymer as a structured liquid, we have...

  13. CERN Scientific Book Fair 2008

    CERN Multimedia

    DSU Unit

    2008-01-01

    The CERN Bookshop and CERN Library invite you to attend the 2008 CERN Book Fair 2008, a three-day scientific book festival offering you the opportunity to meet key publishers and electronic book suppliers and to browse and purchase books at significant discounts. Some ten companies will be participating and will bring with them a selection of titles in physics, technology, mathematics, engineering and popular science. There will also be a number of tie-in events intended to give you an insight into the writing and publishing process from authors within our own community. Come along and meet the authors, discuss your book ideas with the publishers’ representatives or simply browse the books on offer. The Fair will take place in Building 500 in the area near the Main Auditorium, and special presentations (as detailed below) will be held in rooms nearby or in the Library. Participating publishers and book traders include: Cambridge ...

  14. Do Adolescents Prefer Electronic Books to Paper Books?

    Directory of Open Access Journals (Sweden)

    Margaret K. Merga

    2015-11-01

    Full Text Available While electronic books offer a range of benefits and may be supposed to be more appealing to young people than paper books, this assumption is often treated as fact by educational researchers. Understanding adolescents’ true current preferences is essential, as incorrect assumptions can lead to decisions which restrict adolescent access to their preferred book mode. The belief that adolescents prefer electronic books to paper books has already led to some school libraries being expunged of paper books. As adolescents show a higher level of aliteracy than younger children, and regular reading offers a broad range of benefits for young people, it is imperative that school’s decisions around providing access to books are responsive to adolescent students’ genuine preferences. This paper analyses the current and relevant academic research around adolescent preferences for book modes, finding that, at present, the contention that adolescents prefer electronic books is not supported by the available research. In addition, there are a number of issues identified that make analyzing the findings in this area problematic. Future studies in this area are needed before an adolescent preference for electronic books can be unequivocally substantiated.

  15. TWEED Code Book

    OpenAIRE

    Engene, Jan Oskar

    2006-01-01

    The TWEED data set contains information on more than 11.000 events related to internal (or domestic) terrorism in 18 West European countries for the 1950 through 2004 period. The code book describes the structure of the data set, the countries covered, and the variables included and functions as a user’s guide to the data set. The data set is available at: http://www.uib.no/people/sspje/tweed.htm The data set Terrorism in Western Europe: Events Data, TWEED, contains information on events r...

  16. The Twitter Book

    CERN Document Server

    O'Reilly, Tim

    2009-01-01

    This practical guide will teach you everything you need to know to quickly become a Twitter power user, including strategies and tactics for using Twitter's 140-character messages as a serious--and effective--way to boost your business. Co-written by Tim O'Reilly and Sarah Milstein, widely followed and highly respected Twitterers, the practical information in The Twitter Book is presented in a fun, full-color format that's packed with helpful examples and clear explanations.A Sneak Preview on SlideShare

  17. The automotive transmission book

    CERN Document Server

    Fischer, Robert; Jürgens, Gunter; Najork, Rolf; Pollak, Burkhard

    2015-01-01

    This book presents essential information on systems and interactions in automotive transmission technology and outlines the methodologies used to analyze and develop transmission concepts and designs. Functions of and interactions between components and subassemblies of transmissions are introduced, providing a basis for designing transmission systems and for determining their potentials and properties in vehicle-specific applications: passenger cars, trucks, buses, tractors, and motorcycles. With these fundamentals the presentation provides universal resources for both state-of-the-art and future transmission technologies, including systems for electric and hybrid electric vehicles.

  18. Instrumentation reference book

    CERN Document Server

    Boyes, Walt

    2002-01-01

    Instrumentation is not a clearly defined subject, having a 'fuzzy' boundary with a number of other disciplines. Often categorized as either 'techniques' or 'applications' this book addresses the various applications that may be needed with reference to the practical techniques that are available for the instrumentation or measurement of a specific physical quantity or quality. This makes it of direct interest to anyone working in the process, control and instrumentation fields where these measurements are essential.* Comprehensive and authoritative collection of technical information* Writte

  19. The Twitter Book

    CERN Document Server

    O'Reilly, Tim

    2011-01-01

    Twitter is not just for talking about your breakfast anymore. It's become an indispensable communications tool for businesses, non-profits, celebrities, and people around the globe. With the second edition of this friendly, full-color guide, you'll quickly get up to speed not only on standard features, but also on new options and nuanced uses that will help you tweet with confidence. Co-written by two widely recognized Twitter experts, The Twitter Book is packed with all-new real-world examples, solid advice, and clear explanations guaranteed to turn you into a power user. Use Twitter to con

  20. Children’s Book Illustrations: Visual Language of Picture Books

    Directory of Open Access Journals (Sweden)

    Hladíková Hana

    2014-01-01

    Full Text Available High-quality picture books that merge text and illustration together in order to tell a story are eminent for healthy mental and social growth of children. This paper is to outline the benefits picture books bring to children between the ages three to eight, determine functions of its illustrative language, examine the process of its production, and point out a set of elements that, according to number of professional children's book illustrators, significantly contribute to the success of a picture book

  1. CERN Book fair

    CERN Multimedia

    CERN Central Library and IT Department Bookshop

    2004-01-01

    The CERN Library, in conjunction with the IT Department Bookshop, is organizing a book fair on the 28th and 29th October. Some 15 major publishers will be represented, including 6 who will be here in person, and more than 700 of their latest titles will be on display (for sale or order). The major topics covered will be computing, physics, technology, mathematics, engineering and popular science. Those present at this event will include Alpha Science, Cambridge University Press, Elsevier, Institute of Physics, Microsoft Press, O'Reilly, OLF Switzerland, Oxford University Press, McGraw-Hill, Springer, Pearson, Thali Switzerland, Wiley, World Scientific and Ebooks Corporation. The fair will take place on the first floor of the Main Building (bldg.60), Salle des Pas Perdus, and will be open from 10.00 to 17.00 on both days. In addition, EBooks Corporation will describe their electronic book system; insight into this is available at http://www.eblib.com/ We look forward to your support for this initiative. Sh...

  2. Proofs from THE BOOK

    CERN Document Server

    Aigner, Martin

    2014-01-01

    This revised and enlarged fifth edition features four new chapters, which contain highly original and delightful proofs for classics such as the spectral theorem from linear algebra, some more recent jewels like the non-existence of the Borromean rings and other surprises. From the Reviews "... Inside PFTB (Proofs from The Book) is indeed a glimpse of mathematical heaven, where clever insights and beautiful ideas combine in astonishing and glorious ways. There is vast wealth within its pages, one gem after another. ... Aigner and Ziegler... write: "... all we offer is the examples that we have selected, hoping that our readers will share our enthusiasm about brilliant ideas, clever insights and wonderful observations." I do. ... " Notices of the AMS, August 1999 "... This book is a pleasure to hold and to look at: ample margins, nice photos, instructive pictures, and beautiful drawings ... It is a pleasure to read as well: the style is clear and entertaining, the level is close to elementary, the necessary b...

  3. Alzira’s book

    Directory of Open Access Journals (Sweden)

    Maria Do Rosário Longo Mortatti

    2013-01-01

    Full Text Available Aiming it contribute to discussions on teaching and learning of reading and writing, is presented, in the form of critical review, the analysis of textual configuration of the book Será que fui eu ?, by Alzira Silveria. This analysis was developed based on the assumption that reading and producing written texts are specifically human activities whose function and importance beyond the boundaries of the school and change ways of thinking, feeling, will and act, promoting qualitative changes in process of human development and providing active participation in the public world of written culture, and therefore in society and history. This is the main “life lesson” that the author of the book teaches all interested in the subject, especially to school teachers responsible for teaching reading and writing, which can only be successful if and when they understand themselves as historical and social people who, also experience reading and producing written texts, not only as necessary acturties for their teaching performance, but rather as essential activities for human development, of people who are author of their own speech frow and about their life and history.

  4. Preparation and adsorption behaviors of Cu(Ⅱ) ion-imprinted polymers

    Institute of Scientific and Technical Information of China (English)

    ZHONG Shi-an; YUAN Zhou-lv; QIAO Rong; LI Wei

    2008-01-01

    Imprinted polymers were prepared for selective removal of Cu(II) ions from metal solutions. Three ion-imprinted polymers were synthesized with methacrylic acid (MAA), acrylamide (AA) and N,N'-methylenebisacrylamide (MBAA) respectively as the functional monomers, ethleneglycoldimethacrylate (EGDMA) as the cross-linking agent, 2,2'-azobisisobutyronitrile (AIBN) as the initiator and Cu (II) ion as the imprint ion. The template Cu (II) ion was removed from the polymer by leaching with a liquid of a 1:1 volumetric ratio of HCl to ethylenediaminetetraacetic acid (EDTA). The capacity and selectivity of Cu(II) ion adsorption were investigated with the three imprinted polymers and their non-imprinted counterparts. The polymers have a maximum adsorption capacity at pH 7.0. The isotherm of their batch adsorption of Cu(II) ions shows a Langmuir adsorption pattern. Imprinted polymers all have a much higher capacity and higher selectivity of Cu(II) adsorption than non-imprinted ones. MAA polymer benefits the most from imprinting. Imprinted MAA polymer has the highest selectivity when used to rebind Cu (II) ion from an aqueous solution in the presence of other metal ions. Ion imprinting can be a promising technique of preparing selective adsorbents to separate and preconcentrate metal in a medium of multiple competitive metal ions through solid phase extraction (SPE).

  5. Non-coding RNAs and the acquisition of genomic imprinting in mammals

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Genomic imprinting,representing parent-specific expression of alleles at a locus,is mainly evident in flowering plants and placental mammals.Most imprinted genes,including numerous non-coding RNAs,are located in clusters regulated by imprinting control regions(ICRs).The acquisition and evolution of genomic imprinting is among the most fundamental genetic questions.Discoveries about the transition of mammalian imprinted gene domains from their non-imprinted ancestors,especially recent studies undertaken on the most ancient mammalian clades-the marsupials and monotremes from which model species genomes have recently been sequenced,are of high value.By reviewing and analyzing these studies,a close connection between non-coding RNAs and the acquisition of genomic imprinting in mammals is demonstrated.The evidence comes from two observations accompanied with the acquisition of the imprinting:(i) many novel non-coding RNA genes emerged in imprinted regions;(ii) the expressions of some conserved non-coding RNAs have changed dramatically.Furthermore,a systematical analysis of imprinted snoRNA(small nucleolar RNA) genes from 15 vertebrates suggests that the origination of imprinted snoRNAs occurred after the divergence between eutherians and marsupials,followed by a rapid expansion leading to the fixation of major gene families in the eutherian ancestor prior to the radiation of modern placental mammals.Involved in the regulation of imprinted silencing and mediating the chromatins epigenetic modification may be the major roles that non-coding RNAs play during the acquisition of genomic imprinting in mammals.

  6. Molecularly imprinted polymers prepared using protein-conjugated cleavable monomers followed by site-specific post-imprinting introduction of fluorescent reporter molecules.

    Science.gov (United States)

    Suga, Yusuke; Sunayama, Hirobumi; Ooya, Tooru; Takeuchi, Toshifumi

    2013-10-01

    Molecularly imprinted polymers were prepared using a protein-conjugated disulfide cleavable monomer. After removing the protein by disulfide reduction, a thiol-reactive fluorophore was introduced into the thiol residue located only inside the imprinted cavity, resulting in specific transduction of the binding events into fluorescence spectral change.

  7. High volume nanoscale roll-based imprinting using jet and flash imprint lithography

    Science.gov (United States)

    Ahn, Se Hyun; Miller, Mike; Yang, Shuqiang; Ganapathisubramanian, Maha; Menezes, Marlon; Singh, Vik; Choi, Jin; Xu, Frank; LaBrake, Dwayne; Resnick, Douglas J.; Sreenivasan, S. V.

    2013-09-01

    Extremely large-area roll-to-roll (R2R) manufacturing on flexible substrates is ubiquitous for applications such as paper and plastic processing. It combines the benefits of high speed and inexpensive substrates to deliver a commodity product at low cost. The challenge is to extend this approach to the realm of nanopatterning and realize similar benefits. In order to achieve low-cost nanopatterning, it is imperative to move toward high-speed imprinting, less complex tools, near zero waste of consumables, and low-cost substrates. We have developed a roll-based J-FIL process and applied it to a technology demonstrator tool, the LithoFlex 100, to fabricate large-area flexible bilayer wire-grid polarizers (WGPs) and high-performance WGPs on rigid glass substrates. Extinction ratios of better than 10,000 are obtained for the glass-based WGPs. Two simulation packages are also employed to understand the effects of pitch, aluminum thickness, and pattern defectivity on the optical performance of the WGP devices. It is determined that the WGPs can be influenced by both clear and opaque defects in the gratings; however, the defect densities are relaxed relative to the requirements of a high-density semiconductor device.

  8. Becoming Trivial: The Book Trailer

    Directory of Open Access Journals (Sweden)

    Kati Voigt

    2013-12-01

    Full Text Available Despite the introduction of audiobooks and e-books, printed stories still are in high demand. However, in a globalized world which is more and more ruled by mass media and technology, it is increasingly difficult for writers and publishers to promote their books. The solution is almost ironic: popular media, which is assumed to decrease readership, is turned into a tool to increase the number of readers. In 2002 the book trailer emerged as a new web-based marketing strategy for the launch of new books. Since then the appearance of the book trailer has changed considerably. The article examines specific examples and highlights methods that establish the relationship between the content of the book and its representation in the book trailer. Although guidelines apply for the production of book trailers, such as constraints relating to time and content, there are no limitations for the imagination of the producers. A book trailer may be simple, supported only by music and pictures, but they may also be as complex as short films. Additionally, book trailers are not limited to the promotion of one specific genre or age group. Depending on the viral potential of social networks such as YouTube, Facebook, and Tumblr book trailers reach a global audience and, therefore, open up new markets. It can be argued, while book trailers have not yet reached the realm of the everyday, they will gradually come to the attention of academics and this article wants to present a starting point for this development.

  9. Protection mechanisms for electronic books

    OpenAIRE

    Ausderau, Patrick

    2014-01-01

    The research for a new Digital Right Management (DRM) infrastructure for electronic books (e-book) is a task of the eReading project of the Next Media program. The goal of this thesis is to to propose a protection system that could help limiting copyright infringement while allowing fair use of e-books. This thesis reviews the existing DRM system and other protection technologies such as watermarking and social DRM. It studies the upcoming Lightweight Content Protection standard (f...

  10. Printed books and the WWW

    OpenAIRE

    Nieuwenhuysen, Paul

    2010-01-01

    This contribution reports on an ongoing investigation and evaluation of freely available tools on the Internet and WWW to discover information about printed books or to find copies of a particular book for sale. Introduction: Various information needs exist related to books. The Internet and WWW provide many services to discover information. Problem statements / aims: Which information services are available free of charge for all users via the Internet and the WWW, which allow us...

  11. BOOK REVIEW: Synergetics

    Science.gov (United States)

    Eckhardt, B.

    2005-01-01

    The reductionist approach asks us to split the world into its constituents and to develop a detailed understanding of the properties of each fragment. This programme has met with considerable success in many instances, but it fails to account for properties that emerge from the interrelation between constituents and can be seen in the system as a whole only. The reductionist approach explains the spectra and intensities of the light emitted by a single atom, but it does not account for the appearance of coherent lasing action of atoms coupled by their light field. It describes the motion of individual molecules in a liquid but cannot explain how they arrange to form the majestic roll of waves on a beach. Similarly, a brain consists of millions of neurons whose biochemistry is reasonably well understood, but how they interact to give rise to memory and association and the myriad of other tasks a brain is capable off, remains unclear. These and many other examples in the anorganic and living world around us have in common that they typically operate far from thermodynamic equilibrium, that they involve the interaction of many ingredients, and that nonlinear interactions and feedback loops tend to be important. Over the past few decades many aspects of the dynamics of such systems have been explored, and fields like nonlinear dynamics, bifurcation theory, and pattern formation have prospered enourmously. Yet, the connection between the different areas and their contribution to the larger goal of explaining and exploring much of the order out of chaos around us has been in danger of being lost. Hermann Hakens book overcomes this reductionist separation of approaches and disciplines and provides a coherent collection of concepts, methods and tools with which all the previous examples and many more can be addressed. It lays the foundation for a quantitative analysis and should been seen as an invitation to the reader to apply its ideas to his or her favourite phenomenon

  12. Fantasy book illustration and design

    OpenAIRE

    Furjan, Ana

    2015-01-01

    This thesis considers illustrating the fantasy book, The Story of a Past Future, written by the author. The goals were to make illustrations for the book and a map of the world in which the story is happening as well as design the book layout and the cover. This document covers illustration in general, in the fantasy field and in digital environments. It also considers making a book cover. In the first part knowledge about illustration and fantasy art is provided through a research of rel...

  13. Newnes electronics engineers pocket book

    CERN Document Server

    Brindley, Keith

    2013-01-01

    This book is packed with information and material which everyone involved in electronics will find indispensable. Now when you need to know a transistor's characteristics, or an integrated circuit's pinout details, simply look it up! The book is full of tables, symbols, formulae, conversions and illustrations.Promotion via the new Newnes Pocket Book catalogue to the electronics trade will drive sales into the book trade Covers component data; encapsulations; pin-outs; symbols & codings Extensive material on conversion factors, formulae; units and relationships

  14. White book on energies

    International Nuclear Information System (INIS)

    The energy policy in France has to answer two challenges: the first one is the climatic change and the greenhouse effect, the second one is to conceive an energy policy taking into account the evolutions and economical realities. four objectives have to guide the action of the government, the guarantee to the right of access to energy for every citizen, the fight against the climatic warming, the preservation of a national independence, the keeping of a competitive energy. This book includes a summary of works and conclusions of the National Debate on energies, hold during the first semester of 2003, the government propositions, a whole of cards detailing some aspects of government propositions, especially financial propositions. (N.C.)

  15. BOOK REVIEW: Quantum Squeezing

    Science.gov (United States)

    Zubairy, Suhail

    2005-05-01

    Quantum squeezed states are a consequence of uncertainty relations; a state is squeezed when the noise in one variable is reduced below the symmetric limit at the expense of the increased noise in the conjugate variable such that the Heisenberg uncertainty relation is not violated. Such states have been known since the earliest days of quantum mechanics. The realization in the early 80's that quantum squeezed states of the radiation field can have important applications in high precision Michelson interferometry for detecting gravitational waves led to a tremendous amount of activity, both in theoretical and experimental quantum optics. The present volume, edited by two eminent scientists, is a collection of papers by leading experts in the field of squeezed states on different aspects of the field as it stands today. The book is divided into three parts. In the first part, there are three articles that review the fundamentals. The first paper by Knight and Buzek presents an introductory account of squeezed states and their properties. The chapter, which opens with the quantization of the radiation field, goes on to discuss the quantum optical properties of single mode and multimode squeezed states. The second article by Hillery provides a detailed description of field quantization in the presence of a nonlinear dielectric medium, thus providing a rigorous treatment of squeezing in nonlinear media. The third article by Yurke presents a comprehensive discussion of the input-output theory of the squeezed radiation at the dielectric boundaries. The second part of the book, comprising of three articles, deals with the generation of squeezed states. In the first article, Drummond reviews the squeezing properties of light in nonlinear systems such as parametric oscillators. He also discusses squeezed light propagation through waveguides and optical fibers. In the second article, Ralph concentrates on active laser sources of squeezing and presents an analysis based on the

  16. The Cool 100 book

    Energy Technology Data Exchange (ETDEWEB)

    Haselip, J.; Pointing, D.

    2011-07-01

    The aim of The Cool 100 book is to document 100 inspiring, educational and practical examples of sustainable and accessible energy supply solutions created by, or suitable for, isolated communities in the cooler regions of the world. The book features the following projects, explored in detail: 1. Promoting Unst Renewable Energy (PURE) project, a pioneering project that demonstrates how wind power and hydrogen technologies can be combined to meet the energy needs of a remote industrial estate on the island of Unst in the British Isles. 2. The EDISON project, or Electric vehicles in a Distributed and Integrated market using Sustainable energy and Open Networks that explored increased renewable energy use and electric vehicle operation in Denmark, with a case study on the island of Bornholm. 3. The Sarfannguit Wireless Electricity Reading project, which has significantly improved utility metering and enabled improved energy management, reduced electricity demand, and the introduction of renewable energy technologies in the isolated villages of Greenland. 4. The Renewable Energy Croft and Hydrogen facility, which uses innovative technologies to support a gardening facility in the Outer Hebrides (Scotland), and is also a working laboratory for students of the local university to develop a hydrogen energy economy. 5. The Samsoe Renewable Energy Island in Denmark, an iconic example of how an island community can consume only green electricity by using a range of innovative technologies and behavioural changes to reduce demand and to harness green energy resources. 6. The Hydrogen Office Project which demonstrates how a commercial office in the coastal town of Methil in Scotland can be supported by a novel renewable, hydrogen and fuel cell energy system, and how the local community is engaged with the project. 7. The Northern Sustainable House in Nunavut, Canada, which explores the process and results of a project to design and implement housing for local families that

  17. Children's Books in Review: Books on Strengthening Family Ties.

    Science.gov (United States)

    Winfield, Evelyn T.

    1991-01-01

    Reviews children's books that emphasize the strengthening of family ties. Characters in the books realize the importance and influence of family relationships as they struggle with sibling rivalry, self-discovery, peer relationships, a search for heritage, adoption, and death. (SM)

  18. Characterization of the imprinting and expression patterns of ZAG2 in maize endosperm and embryo

    Directory of Open Access Journals (Sweden)

    Chaoxian Liu

    2015-02-01

    Full Text Available ZAG2 has been identified as a maternally expressed imprinted gene in maize endosperm. Our study revealed that paternally inherited ZAG2 alleles were imprinted in maize endosperm and embryo at 14 days after pollination (DAP, and consistently imprinted in endosperm at 10, 12, 16, 18, 20, 22, 24, 26, and 28 DAP in reciprocal crosses between B73 and Mo17. ZAG2 alleles were also imprinted in reciprocal crosses between Zheng 58 and Chang 7-2 and between Huang C and 178. ZAG2 alleles exhibited differential imprinting in hybrids of 178 × Huang C and B73 × Mo17, while in other hybrids ZAG2 alleles exhibited binary imprinting. The tissue-specific expression pattern of ZAG2 showed that ZAG2 was expressed at a high level in immature ears, suggesting that ZAG2 plays important roles in not only kernel but ear development.

  19. Enhanced adsorption of atrazine from aqueous solution by molecularly imprinted TiO2 film

    Science.gov (United States)

    Zhang, Chunjing; Yan, Jinlong; Zhang, Chunxiao; Yang, Zhengpeng

    2012-07-01

    TiO2 film imprinted by atrazine molecule at the surface of quartz crystal was prepared using molecular imprinting and surface sol-gel process. The molecularly imprinted TiO2 film was characterized by scanning electron microscopy and cyclic voltammetry, and the atrazine adsorption was investigated by quartz crystal microbalance (QCM) technique. In comparison with non-imprinted TiO2 film, the molecularly imprinted TiO2 film exhibits high selectivity for atrazine, better reversibility and a much higher adsorption capacity for the target molecule, the adsorption equilibrium constant estimated from the in situ frequency measurement is about 6.7 × 104 M-1, which is thirteen times higher than that obtained on non-imprinted TiO2 film.

  20. Chemical Sensors Based on Molecularly Imprinted Sol-Gel Materials

    Directory of Open Access Journals (Sweden)

    Franz L. Dickert

    2010-03-01

    Full Text Available The sol-gel technique is earning the worldwide attention of researchers in the field of material science, due to its versatility in synthesizing inorganic ceramic materials at mild conditions. High purity, homogeneity, controlled porosity, stable temperature and nanoscale structuring are the most remarkable features offered by this method for generating highly sensitive and selective matrices to incorporate analyte molecules. The crafting of sol-gel sensors through molecular imprinting has put great influence on the development of innovative chemical sensors, which can be seen from the growing number of publications in this field. The review provides a brief overview of sol-gel sensor applications, and discusses the contribution of molecular imprinting in exploring the new world of sensors.

  1. Magnetic molecularly imprinted polymer for aspirin recognition and controlled release

    Energy Technology Data Exchange (ETDEWEB)

    Kan Xianwen; Geng Zhirong; Zhao Yao; Wang Zhilin; Zhu Junjie [State Key Laboratory of Coordination Chemistry, MOE Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093 (China)], E-mail: wangzl@nju.edu.cn, E-mail: jjzhu@nju.edu.cn

    2009-04-22

    Core-shell structural magnetic molecularly imprinted polymers (magnetic MIPs) with combined properties of molecular recognition and controlled release were prepared and characterized. Magnetic MIPs were synthesized by the co-polymerization of methacrylic acid (MAA) and trimethylolpropane trimethacrylate (TRIM) around aspirin (ASP) at the surface of double-bond-functionalized Fe{sub 3}O{sub 4} nanoparticles in chloroform. The obtained spherical magnetic MIPs with diameters of about 500 nm had obvious superparamagnetism and could be separated quickly by an external magnetic field. Binding experiments were carried out to evaluate the properties of magnetic MIPs and magnetic non-molecularly imprinted polymers (magnetic NIPs). The results demonstrated that the magnetic MIPs had high adsorption capacity and selectivity to ASP. Moreover, release profiles and release rate of ASP from the ASP-loaded magnetic MIPs indicated that the magnetic MIPs also had potential applications in drug controlled release.

  2. Magnetization dynamics of imprinted non-collinear spin textures

    Energy Technology Data Exchange (ETDEWEB)

    Streubel, Robert, E-mail: r.streubel@ifw-dresden.de; Kopte, Martin; Makarov, Denys, E-mail: d.makarov@ifw-dresden.de [Institute for Integrative Nanosciences, IFW Dresden, 01069 Dresden (Germany); Fischer, Peter [Center for X-Ray Optics, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Physics Department, UC Santa Cruz, Santa Cruz, California 95064 (United States); Schmidt, Oliver G. [Institute for Integrative Nanosciences, IFW Dresden, 01069 Dresden (Germany); Material Systems for Nanoelectronics, Chemnitz University of Technology, 09107 Chemnitz (Germany)

    2015-09-14

    We study the magnetization dynamics of non-collinear spin textures realized via imprint of the magnetic vortex state in soft permalloy into magnetically hard out-of-plane magnetized Co/Pd nanopatterned heterostructures. Tuning the interlayer exchange coupling between soft- and hard-magnetic subsystems provides means to tailor the magnetic state in the Co/Pd stack from being vortex- to donut-like with different core sizes. While the imprinted vortex spin texture leads to the dynamics similar to the one observed for vortices in permalloy disks, the donut-like state causes the appearance of two gyrofrequencies characteristic of the early and later stages of the magnetization dynamics. The dynamics are described using the Thiele equation supported by the full scale micromagnetic simulations by taking into account an enlarged core size of the donut states compared to magnetic vortices.

  3. The ISW imprints of voids and superclusters on the CMB

    Science.gov (United States)

    Hotchkiss, S.; Nadathur, S.; Gottlöber, S.; Iliev, I. T.; Knebe, A.; Watson, W. A.; Yepes, G.

    2016-10-01

    We examine the stacked integrated Sachs-Wolfe (ISW) imprints on the CMB along the lines of sight of voids and superclusters in galaxy surveys, using the Jubilee ISW simulation and mock luminous red galaxy (LRG) catalogues. We show that the expected signal in the concordance \\Lam CDM model is much smaller than the primary anisotropies arising at the last scattering surface and therefore any currently claimed detections of such an imprint cannot be caused by the ISW effect in \\Lam CDM. We look for the existence of such a signal in the Planck CMB using a catalogue of voids and superclusters from the Sloan Digital Sky Survey (SDSS), but find a result completely consistent with \\Lam CDM - i.e., a null detection.

  4. Ducklings imprint on the relational concept of "same or different".

    Science.gov (United States)

    Martinho, Antone; Kacelnik, Alex

    2016-07-15

    The ability to identify and retain logical relations between stimuli and apply them to novel stimuli is known as relational concept learning. This has been demonstrated in a few animal species after extensive reinforcement training, and it reveals the brain's ability to deal with abstract properties. Here we describe relational concept learning in newborn ducklings without reinforced training. Newly hatched domesticated mallards that were briefly exposed to a pair of objects that were either the same or different in shape or color later preferred to follow pairs of new objects exhibiting the imprinted relation. Thus, even in a seemingly rigid and very rapid form of learning such as filial imprinting, the brain operates with abstract conceptual reasoning, a faculty often assumed to be reserved to highly intelligent organisms. PMID:27418508

  5. Composite vascular repair grafts via micro-imprinting and electrospinning

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yuanyuan, E-mail: yuanyuan-liu@shu.edu.cn; Hu, Qingxi, E-mail: huqingxi@shu.edu.cn [Rapid Manufacturing Engineering Center, Shanghai University, Shanghai 200444 (China); Shanghai Key Laboratory of Intelligent Manufacturing and Robotics, Shanghai 200072 (China); Xiang, Ke, E-mail: xiangke@shu.edu.cn; Chen, Haiping, E-mail: 519673062@qq.com; Li, Yu, E-mail: liyu@hpu.edu.cn [Rapid Manufacturing Engineering Center, Shanghai University, Shanghai 200444 (China)

    2015-04-15

    Composite vascular grafts formed by micro-imprinting and electrospinning exhibited improved mechanical properties relative to those formed by electrospinning alone. The three-layered composite grafts mimic the three-layered structure of natural blood vessels. The middle layer is made by micro-imprinting poly-p-dioxanone (PPDO), while the inner and outer layers are electrospun mixtures of chitosan and polyvinyl alcohol. The graft morphology is characterized with scanning electron microscopy. For constant graft thicknesses, the PPDO increases the mechanical strength. Cells cultivated on the vascular grafts adhere and proliferate better because of the natural, biological chitosan in the inner and outer layers. Overall, the composite scaffolds could be good candidates for blood vessel repair.

  6. Biotin-specific synthetic receptors prepared using molecular imprinting

    Energy Technology Data Exchange (ETDEWEB)

    Piletska, Elena; Piletsky, Sergey; Karim, Kal; Terpetschnig, Ewald; Turner, Anthony

    2004-02-16

    The composition of new molecularly imprinted polymers (MIPs) specific for biotin was optimised using molecular modelling software. Three functional monomers: methacrylic acid (MAA), 2-(trifluoromethyl)acrylic acid (TFAA) and 2-acrylamido-2-methylpropanesulfonic acid (AMPSA), which demonstrated the highest binding scores with biotin, were tested on their ability to generate specific binding sites. The imprinted polymers were photografted to the surface of polystyrene microspheres in water. The affinity of the synthetic 'receptor' sites was evaluated in binding experiments using horseradish peroxidase-labelled biotin. Good correlation was found between the modelling results and the performance of the materials in the template re-binding study. The dissociation constants for all MIPs were 1.4-16.8 nM, which is sufficient for most analytical applications where biotin is used as a label.

  7. Monocrotophos Molecularly Imprinted Microspheres Prepared by Precipitation Polymerization in Acetonitrile

    Institute of Scientific and Technical Information of China (English)

    Shoulei Yan; Zhixian Gao; Yanjun Fang; Yiyong Cheng

    2006-01-01

    Molecularly imprinted microspheres (MIP) for monocrotophos have been prepared by precipitation polymerization in acetonitrile (CAN) 60℃, 24 h, using methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA) and 2,2-azobisiobutyronitrile (AIBN) as functional monomer, cross-linker and initiator, respectively. The recognition mechanism was elucidated by UV-vis spectra and computer modeling. Equilibrium binding experiment was employed to investigate the rebinding properties, Scatchard analysis showed that specific binding sites formed in the imprinted microspheres, and there were two kinds of binding sites, one was high binding sites, the other was low binding sites. This microspheres can be useful affinity absorbent used for organophosphorus pesticides separation and purification in food and environmental analysis.

  8. Composite vascular repair grafts via micro-imprinting and electrospinning

    Science.gov (United States)

    Liu, Yuanyuan; Xiang, Ke; Chen, Haiping; Li, Yu; Hu, Qingxi

    2015-04-01

    Composite vascular grafts formed by micro-imprinting and electrospinning exhibited improved mechanical properties relative to those formed by electrospinning alone. The three-layered composite grafts mimic the three-layered structure of natural blood vessels. The middle layer is made by micro-imprinting poly-p-dioxanone (PPDO), while the inner and outer layers are electrospun mixtures of chitosan and polyvinyl alcohol. The graft morphology is characterized with scanning electron microscopy. For constant graft thicknesses, the PPDO increases the mechanical strength. Cells cultivated on the vascular grafts adhere and proliferate better because of the natural, biological chitosan in the inner and outer layers. Overall, the composite scaffolds could be good candidates for blood vessel repair.

  9. Chiral separation of racemic drugs using molecular imprinting

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Molecularly imprinted polymers (MIPs) of (S)-ketoprofen and (S)-naproxen are prepared using non-covalent imprinting in the presence of template molecules. The prepared MIPs are used as the chiral stationary phase to separate ramemic naproxen and ketoprofen. The results show that racemic naproxen and ketoprofen are efficiently resolved on MIPs. The effect of concentration of acetic acid in the mobile phase is studied, and the data are analyzed using the affinity chromatography model, and the close agreement is achieved between the simulated and experimental curves. The results suggest that the affinity chromatography mechanism controls the retention in this system. Moreover, the affinity chromatography equilibrium constants on (S)-naproxen and (S)-ketoprofen are estimated.

  10. CERN Book Fair 2010 - Events and book presentations

    CERN Multimedia

    CERN Library

    2010-01-01

    A series of events and book presentations is scheduled for the 2010 CERN Book Fair.   -Springer will present its new products and services (eBooks, MyCopy Softcover Editions, SpringerBriefs, and a new physics journal: "Historical Perspectives on Contemporary Physics") and SpringerMaterials, the electronic version of the Landolt Boernstein book series. -Wiley will present two books: "A History of International Research Networking : The People who Made it Happen", edited by B. Bressan and H. Davies, and "Field computation for accelerator magnets : analytical and numerical methods for electromagnetic design and optimization" by S. Russenschuck. -Finally, World Scientific will present the series "Reviews of Accelerator Science and Technology (RAST)". The calendar is available here: http://indico.cern.ch/conferenceDisplay.py?confId=105651      

  11. Preparation and Characterization of Nonylphenol Magnetic Molecularly Imprinted Polymer

    International Nuclear Information System (INIS)

    Nonylphenol (NP) is a toxic xenobiotic compound classified as an endocrine disrupter, which can interface with the hormonal system of numerous organisms, and then cause a series of pathological changes. It is of great significance to remove nonyl phenol from the environment. In this paper, an effective method for the preparation of molecularly imprinted nanoparticles was reported. Firstly, Fe/sub 3/O/sub 4/ at the rate SiO/sub 2/ magnetic carrier material modified by trimethoxysilane was achieved through three-step reaction. After that, the selective magnetic molecularly imprinted polymer sorbent for NP (Fe/sub 3/O/sub 4/ at the rate SiO/sub 2/-MIP) was synthesized by surface molecular imprinting technique, using NP as template, 4-vinyl pyridine(4-Vpy) as functional monomers, ethylene glycol dimethacrylate (EGDMA) as cross linker and azobisisobutyronitrile (AIBN) as initiator. The morphous, composition, structure and performance of polymer adsorbent was characterized by SEM, TEM, FT-IR, XRD, EDS, VSM and nitrogen adsorption-desorption techniques. The results indicated that the polymer adsorbent was successfully prepared. The size of the polymer particle was about 50 nm, the aperture on the surface was 3.71 nm, the BET specific surface area was 61.80 m/sup 2/g and the Langmuir specific surface area was 101.24 m/sup 2/g. The selective adsorption rate for NP of 0.5 mmol/L attained value of 86.5%, and for NP with low concentration (less than 2.0 mg/L), the selective adsorption rate reached more than 90%. The synthesized magnetic molecularly imprinted polymer had higher selective recognition ability towards the template molecule nonylphenol. It has good magnetism and can be rapidly separated after being employed by using adscititious magnetic field. It has potential application value in treatment and enrichment of nonylphenol. (author)

  12. Microcontact imprinted surface plasmon resonance sensor for myoglobin detection

    Energy Technology Data Exchange (ETDEWEB)

    Osman, Bilgen [Uludag University, Department of Chemistry, Bursa (Turkey); Uzun, Lokman [Hacettepe University, Department of Chemistry, Ankara (Turkey); Beşirli, Necati [Uludag University, Department of Chemistry, Bursa (Turkey); Denizli, Adil, E-mail: denizli@hacettepe.edu.tr [Hacettepe University, Department of Chemistry, Ankara (Turkey)

    2013-10-15

    In this study, we prepared surface plasmon resonance (SPR) sensor using the molecular imprinting technique for myoglobin detection in human serum. For this purpose, we synthesized myoglobin imprinted poly(hydroxyethyl methacrylate-N-methacryloyl-L-tryptophan methyl ester) [poly(HEMA-MATrp)] nanofilm on the surface of SPR sensor. We also synthesized non-imprinted poly(HEMA-MATrp) nanofilm without myoglobin for the control experiments. The SPR sensor was characterized with contact angle measurements, atomic force microscopy, X-ray photoelectron spectroscopy, and ellipsometry. We investigated the effectiveness of the sensor using the SPR system. We evaluated the ability of SPR sensor to sense myoglobin with myoglobin solutions (pH 7.4, phosphate buffer) in different concentration range and in the serum taken from a patient with acute myocardial infarction. We found that the Langmuir adsorption model was the most suitable for the sensor system. The detection limit was 87.6 ng/mL. In order to show the selectivity of the SPR sensor, we investigated the competitive detection of myoglobin, lysozyme, cytochrome c and bovine serum albumin. The results showed that the SPR sensor has high selectivity and sensitivity for myoglobin. - Highlights: • Micro-contact imprinted surface plasmon resonance sensor. • Real-time myoglobin detection in the serum taken from a patient with acute myocardial infarction • Reproducible results for consecutive myoglobin solution supplement • LOD and LOQ values of the SPR sensor were determined to be 26.3 and 87.6 ng/mL. • The SPR sensor has potential for myoglobin sensing during acute MI cases.

  13. Unravelling and controlling hidden imprint fields in ferroelectric capacitors

    OpenAIRE

    Fanmao Liu; Ignasi Fina; Riccardo Bertacco; Josep Fontcuberta

    2016-01-01

    Ferroelectric materials have a spontaneous polarization that can point along energetically equivalent, opposite directions. However, when ferroelectric layers are sandwiched between different metallic electrodes, asymmetric electrostatic boundary conditions may induce the appearance of an electric field (imprint field, E imp) that breaks the degeneracy of the polarization directions, favouring one of them. This has dramatic consequences on functionality of ferroelectric-based devices such as ...

  14. Possible role of imprinting in the Turner phenotype.

    OpenAIRE

    Chu, C E; Donaldson, M D; Kelnar, C J; Smail, P. J.; Greene, S A; Paterson, W.F.; Connor, J M

    1994-01-01

    We have attempted to investigate the role of imprinting in the phenotype of Turner's syndrome. Sixty-three patients were investigated for parental origin of the retained normal X chromosome; 43 were found to retain the maternal X (XM) and 20 the paternal (XP). The relationship between a child's pretreatment height centile and parental height centiles was examined in 36 patients. No significant correlation was found between child and parental height centiles for XP or child and paternal height...

  15. From book to eBook : towards a print conception of the eBook

    OpenAIRE

    2005-01-01

    Denne avhandlingen er en analyse av eBook som beskrevet av to eBook forlag via ebooks.com og ereader.com på internett. Avhandlingen inkluderer også en analyse av tre andre programmer; Abode Reader, Microsoft Reader og eReader. Ut fra websidens innhold som fokuserer på en visuell presentasjon av eBook og språket som blir brukt i forbindelse med eBook så vil analysen ta dette i betraktning. I forbindelse med reader programmet så vil den visuelle presentasjonen, funksjoner, skriveområde og sp...

  16. Molecular Imprinting Fibrous Membranes of Poly(acrylonitrile-co-acrylic acid) Prepared by Electrospinning

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Introduction Over the past few decades, molecular imprinting has been described as a technology for preparing "molecular doors" which can be matched to "template keys". It has been found to be a simple and effective approach to introduce specific recognition sites into synthetic polymers, namely, to create molecular imprinting polymers[1-4]. Remarkable features such as stability,ease of preparation and low cost, have made molecular imprinting polymers particularly attractive in chemical sensors, catalysis, drug delivery, and dedicated separations.

  17. On the Detection of Imprinted Quantitative Trait Loci in Line Crosses: Effect of Linkage Disequilibrium

    OpenAIRE

    Sandor, Cynthia; Georges, Michel

    2008-01-01

    Imprinted quantitative trait loci (QTL) are commonly reported in studies using line-cross designs, especially in livestock species. It was previously shown that such parent-of-origin effects might result from the nonfixation of QTL alleles in one or both parental lines, rather than from genuine molecular parental imprinting. We herein demonstrate that if linkage disequilibrium exists between marker loci and nonfixed QTL, spurious detection of pseudo-imprinting is increased by an additional 40...

  18. Shape-engineered multifunctional porous silicon nanoparticles by direct imprinting.

    Science.gov (United States)

    Mares, Jeremy W; Fain, Joshua S; Beavers, Kelsey R; Duvall, Craig L; Weiss, Sharon M

    2015-07-10

    A versatile and scalable method for fabricating shape-engineered nano- and micrometer scale particles from mesoporous silicon (PSi) thin films is presented. This approach, based on the direct imprinting of porous substrates (DIPS) technique, facilitates the generation of particles with arbitrary shape, ranging in minimum dimension from approximately 100 nm to several micrometers, by carrying out high-pressure (>200 MPa) direct imprintation, followed by electrochemical etching of a sub-surface perforation layer and ultrasonication. PSi particles (PSPs) with a variety of geometries have been produced in quantities sufficient for biomedical applications (≫10 μg). Because the stamps can be reused over 150 times, this process is substantially more economical and efficient than the use of electron beam lithography and reactive ion etching for the fabrication of nanometer-scale PSPs directly. The versatility of this fabrication method is demonstrated by loading the DIPS-imprinted PSPs with a therapeutic peptide nucleic acid drug molecule, and by vapor deposition of an Au coating to facilitate the use of PSPs as a photothermal contrast agent.

  19. Monolithic molecularly imprinted polymeric capillary columns for isolation of aflatoxins.

    Science.gov (United States)

    Szumski, Michał; Grzywiński, Damian; Prus, Wojciech; Buszewski, Bogusław

    2014-10-17

    Monolithic molecularly imprinted polymers extraction columns have been prepared in fused-silica capillaries by UV or thermal polymerization in a two-step process. First, a poly-(trimethylolpropane trimethacrylate) (polyTRIM) core monolith was synthesized either by UV or thermal polymerization. Then it was grafted with the mixture of methacrylic acid (MAA) as a functional monomer, ethylene dimethacrylate (EDMA) as a cross-linking agent, 5,7-dimethoxycoumarin (DMC) as an aflatoxin-mimicking template, toluene as a porogen solvent and 2,2-azobis-(2-methylpropionitrile) (AIBN) as an initiator of the polymerization reaction. Different thermal condition of the photografting and different concentrations of the grafting mixture were tested during polymerization. The extraction capillary columns were evaluated in the terms of their hydrodynamic and chromatographic properties. Retention coefficients for aflatoxin B1 and DMC were used for assessment of the selectivity and imprinting factor. The obtained results indicate that the temperature of photografting and concentration of the grafting mixture are key parameters that determine the quality of the prepared MIPs. From the MIP columns characterized by the highest permeability the column of the highest imprinting factor was applied for isolation of aflatoxins B1, B2, G1 and G2 from the model aqueous sample followed by on-line chromatographic separation. The process was performed using a micro-MISPE-microLC-LIF system of a novel design, which allowed for detection of the eluates from the sample preparation part as well as from the chromatographic separation.

  20. Monolithic molecularly imprinted polymeric capillary columns for isolation of aflatoxins.

    Science.gov (United States)

    Szumski, Michał; Grzywiński, Damian; Prus, Wojciech; Buszewski, Bogusław

    2014-10-17

    Monolithic molecularly imprinted polymers extraction columns have been prepared in fused-silica capillaries by UV or thermal polymerization in a two-step process. First, a poly-(trimethylolpropane trimethacrylate) (polyTRIM) core monolith was synthesized either by UV or thermal polymerization. Then it was grafted with the mixture of methacrylic acid (MAA) as a functional monomer, ethylene dimethacrylate (EDMA) as a cross-linking agent, 5,7-dimethoxycoumarin (DMC) as an aflatoxin-mimicking template, toluene as a porogen solvent and 2,2-azobis-(2-methylpropionitrile) (AIBN) as an initiator of the polymerization reaction. Different thermal condition of the photografting and different concentrations of the grafting mixture were tested during polymerization. The extraction capillary columns were evaluated in the terms of their hydrodynamic and chromatographic properties. Retention coefficients for aflatoxin B1 and DMC were used for assessment of the selectivity and imprinting factor. The obtained results indicate that the temperature of photografting and concentration of the grafting mixture are key parameters that determine the quality of the prepared MIPs. From the MIP columns characterized by the highest permeability the column of the highest imprinting factor was applied for isolation of aflatoxins B1, B2, G1 and G2 from the model aqueous sample followed by on-line chromatographic separation. The process was performed using a micro-MISPE-microLC-LIF system of a novel design, which allowed for detection of the eluates from the sample preparation part as well as from the chromatographic separation. PMID:25218633

  1. Morpho peleides butterfly wing imprints as structural colour stamp.

    Science.gov (United States)

    Zobl, Sigrid; Salvenmoser, Willi; Schwerte, Thorsten; Gebeshuber, Ille C; Schreiner, Manfred

    2016-02-02

    This study presents the replication of a color-causing nanostructure based on the upper laminae of numerous cover scales of Morpho peleides butterfly wings and obtained solely by imprinting their upper-wing surfaces. Our results indicate that a simple casting technique using a novel integrated release agent can obtain a large positive replica using negative imprints via Polyvinylsiloxane. The developed method is low-tech and high-yield and is thus substantially easier and less expensive than previous methods. The microstructures were investigated with light microscopy, the nanostructures with both scanning and transmission electron microscopy, and the reflections with UV visible spectrometry. The influence of the release agent and the quality of the master stamp were determined by comparing measurements of the cover-scale sizes and their chromaticity values obtained by their images and with their positive imprints. The master stamp provided multiple positive replicas up to 3 cm(2) in just 1 h with structural coloration effects visible to the naked eye. Thus, the developed method proves the accuracy of the replicated nanostructure and its potential industrial application as a color-producing nanostamp.

  2. The Common Vision. Reviews: Books.

    Science.gov (United States)

    Chattin-McNichols, John

    1998-01-01

    Reviews Marshak's book describing the work of educators Maria Montessori, Rudolf Steiner, Aurobindo Ghose, and Inayat Khan. Maintains that the book gives clear, concise information on each educator and presents a common vision for children and their education; also maintains that it gives theoretical and practical information and discusses…

  3. The Weekend Education Source Book.

    Science.gov (United States)

    Cross, Wilbur

    A guidebook to short residential programs, the book provides an account of the many types of centers, the wide range of subjects, accommodations/facilities, and the procedures for enrollment and obtaining degrees/credits. The book was written in response to a deluge of inquiries to a "Reader's Digest" article on the topic. The first half of the…

  4. Connect the Book. Benjamin Franklin

    Science.gov (United States)

    Brodie, Carolyn S.

    2004-01-01

    This article presents a brief review of James Cross Giblin's "The Amazing Life of Benjamin Franklin" (Scholastic, 2000). This book provides a real look at the life of one of America's most famous statesmen who was also a printer, inventor, and writer. The book additionally includes a chronology of Franklin's life, information about his many…

  5. The "Adulteration" of Children's Books.

    Science.gov (United States)

    Carr, Jo

    1984-01-01

    Suggesting that children's books have become more adult in content and tone, this essay addresses problem of organization of children's library materials to provide access to adult readers. Extent of adult appeal in children's books, examples of "adulterated" nonfiction and fiction, and questions concerning organizational and attitudinal changes…

  6. How to Get Greener Books

    Science.gov (United States)

    Malone, Cynthia N.

    2008-01-01

    Professors select readings for their students in different forms: printed matter, including books and journals; print-on-demand texts; and online material. Before long, enough books and articles will be available for downloading onto devices like the Sony Reader and Amazon.com's new Kindle to make that format another option. They consider a wide…

  7. Genomic imprinting in the Arabidopsis embryo is partly regulated by PRC2.

    Science.gov (United States)

    Raissig, Michael T; Bemer, Marian; Baroux, Célia; Grossniklaus, Ueli

    2013-01-01

    Genomic imprinting results in monoallelic gene expression in a parent-of-origin-dependent manner and is regulated by the differential epigenetic marking of the parental alleles. In plants, genomic imprinting has been primarily described for genes expressed in the endosperm, a tissue nourishing the developing embryo that does not contribute to the next generation. In Arabidopsis, the genes MEDEA (MEA) and PHERES1 (PHE1), which are imprinted in the endosperm, are also expressed in the embryo; whether their embryonic expression is regulated by imprinting or not, however, remains controversial. In contrast, the maternally expressed in embryo 1 (mee1) gene of maize is clearly imprinted in the embryo. We identified several imprinted candidate genes in an allele-specific transcriptome of hybrid Arabidopsis embryos and confirmed parent-of-origin-dependent, monoallelic expression for eleven maternally expressed genes (MEGs) and one paternally expressed gene (PEG) in the embryo, using allele-specific expression analyses and reporter gene assays. Genetic studies indicate that the Polycomb Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. In the seedling, all embryonic MEGs and the PEG are expressed from both parents, suggesting that the imprint is erased during late embryogenesis or early vegetative development. Our finding that several genes are regulated by genomic imprinting in the Arabidopsis embryo clearly demonstrates that this epigenetic phenomenon is not a unique feature of the endosperm in both monocots and dicots.

  8. Genomic imprinting in the Arabidopsis embryo is partly regulated by PRC2.

    Directory of Open Access Journals (Sweden)

    Michael T Raissig

    Full Text Available Genomic imprinting results in monoallelic gene expression in a parent-of-origin-dependent manner and is regulated by the differential epigenetic marking of the parental alleles. In plants, genomic imprinting has been primarily described for genes expressed in the endosperm, a tissue nourishing the developing embryo that does not contribute to the next generation. In Arabidopsis, the genes MEDEA (MEA and PHERES1 (PHE1, which are imprinted in the endosperm, are also expressed in the embryo; whether their embryonic expression is regulated by imprinting or not, however, remains controversial. In contrast, the maternally expressed in embryo 1 (mee1 gene of maize is clearly imprinted in the embryo. We identified several imprinted candidate genes in an allele-specific transcriptome of hybrid Arabidopsis embryos and confirmed parent-of-origin-dependent, monoallelic expression for eleven maternally expressed genes (MEGs and one paternally expressed gene (PEG in the embryo, using allele-specific expression analyses and reporter gene assays. Genetic studies indicate that the Polycomb Repressive Complex 2 (PRC2 but not the DNA METHYLTRANSFERASE1 (MET1 is involved in regulating imprinted expression in the embryo. In the seedling, all embryonic MEGs and the PEG are expressed from both parents, suggesting that the imprint is erased during late embryogenesis or early vegetative development. Our finding that several genes are regulated by genomic imprinting in the Arabidopsis embryo clearly demonstrates that this epigenetic phenomenon is not a unique feature of the endosperm in both monocots and dicots.

  9. Imprinting Salmon and Steelhead Trout for Homing, 1983 Annual Report of Research.

    Energy Technology Data Exchange (ETDEWEB)

    Slatick, Emil

    1984-09-01

    The National Marine Fisheries Service (NMFS), under contract to the Bonneville Power Administration, began conducting research on imprinting Pacific salmon and steelhead for homing in 1978. In the juvenile marking phase, over 4 million juvenile salmon and steelhead were marked and released in 23 experiments. The primary objectives were to determine a triggering mechanism to activate the homing imprint, if a single imprint or a sequential imprint is necessary to assure homing, and the relationship between the physiological condition of fish and their ability to imprint. Ten experimental studies are discussed. Six of the studies employed a variety of techniques for imprinting fish. The remaining four tested the feasibility of imprinting fish by a short-distance voluntary migration before transport. In five experiments, survival was enhanced by the imprint-transportation procedures, and homing to the homing site area was partly successful. Returns from the Astoria, Oregon, release of fall chinook salmon from Big Creek Hatchery (Knappa, Oregon), for example, showed that limited short distance migration imprinting should provide 2-3 time more fish to the various fisheries while providing adequate returns to the hatchery for egg take each year. 21 refs., 12 figs, 12 tabs.

  10. Secondary imprinting in the domestic chick: Binocular and lateralized monocular performance

    OpenAIRE

    Vallortigara, Giorgio; Regolin, Lucia; Zucca, Paolo

    2000-01-01

    Newly-hatched chicks were reared with a coloured imprinting object on day 1 of life (primary imprinting) and then with an object of a different colour (secondary imprinting) on day 2. They were then tested on day 3 for preferences between the primary and the secondary imprinting object in binocular and in monocular conditions. The main results were that (1) left-eyed chicks usually showed clearer choice than right-eyed chicks; (2) there were colour preferences that appeared to affect choice d...

  11. MacBook for dummies

    CERN Document Server

    Chambers , Mark L

    2014-01-01

    Make friends with your MacBook the fun and easy way! Ultra-light, ultra-fast, and ultra-powerful, the MacBook is the coolest laptop in town, and longtime Mac guru Mark L. Chambers is just the guy to help you get to know your MacBook in no time. Take a closer look at the latest features, get the lowdown on OS X, unleash your creative forces with iLife, take care of business with the iWork applications, and sync it all with iCloud with the expert advice in this bestselling MacBook guide. Whether this is your first MacBook or your first laptop, period, you''ll learn to navigate the Mac desktop, c

  12. BOOK REVIEW: Minority Games

    Science.gov (United States)

    Metzler, R.

    2005-02-01

    New branches of scientific disciplines often have a few paradigmatic models that serve as a testing ground for theories and a starting point for new inquiries. In the late 1990s, one of these models found fertile ground in the growing field of econophysics: the Minority Game (MG), a model for speculative markets that combined conceptual simplicity with interesting emergent behaviour and challenging mathematics. The two basic ingredients were the minority mechanism (a large number of players have to choose one of two alternatives in each round, and the minority wins) and limited rationality (each player has a small set of decision rules, and chooses the more successful ones). Combining these, one observes a phase transition between a crowded and an inefficient market phase, fat-tailed price distributions at the transition, and many other nontrivial effects. Now, seven years after the first paper, three of the key players—Damien Challet, Matteo Marsili and Yi-Cheng Zhang—have published a monograph that summarizes the current state of the science. The book consists of two parts: a 100-page overview of the various aspects of the MG, and reprints of many essential papers. The first chapters of Part I give a well-written description of the motivation and the history behind the MG, and then go into the phenomenology and the mathematical treatment of the model. The authors emphasize the `physics' underlying the behaviour and give coherent, intuitive explanations that are difficult to extract from the original papers. The mathematics is outlined, but calculations are not carried out in great detail (maybe they could have been included in an appendix). Chapter 4 then discusses how and why the MG is a model for speculative markets, how it can be modified to give a closer fit to observed market statistics (in particular, reproducing the `stylized facts' of fat-tailed distributions and volatility clustering), and what conclusions one can draw from the behaviour of the MG

  13. Inciting Interest in the Newbery Award Books

    Science.gov (United States)

    Hegel, Claudette

    2007-01-01

    Hearing some fun facts about books and authors can bring books to life and help ignite students' interest in books and reading. Because most elementary school media centers and public libraries have many of the Newbery Medal books, students will have a better chance of finding books they decide they want to read once they hear about them. Reading…

  14. Libraries, Patrons, and E-Books

    Science.gov (United States)

    Zickuhr, Kathryn; Rainie, Lee; Purcell, Kristen; Madden, Mary; Brenner, Joanna

    2012-01-01

    This report explores the world of e-books and libraries, where libraries fit into these book-consumption patterns of Americans, when people choose to borrow their books and when they choose to buy books. It examines the potential frustrations e-book borrowers can encounter when checking out digital titles, such as long wait lists and compatibility…

  15. What Do Digital Books Mean for Libraries?

    Science.gov (United States)

    Lynch, Clifford

    2001-01-01

    Discusses digital books, or electronic books, and their relationship to libraries and communication between authors and readers. Topics include the scholarly market, for academic libraries, versus the consumer market; textbooks versus novels; digitization of older books; marketing; costs; and electronic books versus printed books. (LRW)

  16. BOOK REVIEW: Modern Supersymmetry

    Science.gov (United States)

    Kulish, Petr P.

    2006-12-01

    S/CFT correspondence. The author explains clearly most of the arguments in discussions and refers for further details to original papers (with corresponding arXiv numbers), selected lists of which appear at the end of each chapter (there are more than 300 references in the book). Considered as a whole the book covers primers on quantum fields, Feynman diagrams, renormalization procedure and renormalization groups, as well as the representation theory of classical linear Lie algebras. Some necessary information on irreducible representations of su(N), so(N) and sp(2N) is given in an appendix. There are in the text short historical and biographical notes concerning those scientists who made important contributions to the subject of the monograph: S Coleman, Yu Golfand, E Witten and others. Most of the seventeen chapters contain a few exercises to check the reader's understanding of the corresponding material. This monograph will be useful for graduate students and researchers in the field of elementary particles.

  17. University contracts summary book

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-08-01

    The principal objectives of the Fossil Energy Program are to seek new ideas, new data, fundamental knowledge that will support the ongoing programs, and new processes to better utilize the nation's fossil energy resources with greater efficiency and environmental acceptability. Toward this end, the Department of Energy supports research projects conducted by universities and colleges to: Ensure a foundation for innovative technology through the use of the capabilities and talents in our academic institutions; provide an effective, two-way channel of communication between the Department of Energy and the academic community; and ensure that trained technical manpower is developed to carry out basic and applied research in support of DOE's mission. Fossil Energy's university activities emphasize the type of research that universities can do best - research to explore the potential of novel process concepts, develop innovative methods and materials for improving existing processes, and obtain fundamental information on the structure of coal and mechanisms of reactions of coal, shale oil, and other fossil energy sources. University programs are managed by different Fossil Energy technical groups; the individual projects are described in greater detail in this book. It is clear that a number of research areas related to the DOE Fossil Energy Program have been appropriate for university involvement, and that, with support from DOE, university scientific and technical expertise can be expected to continue to play a significant role in the advancement of fossil energy technology in the years to come.

  18. Mysteries of a Child's World (Children's Books).

    Science.gov (United States)

    Pierce, Kathryn Mitchell; And Others

    1995-01-01

    Offers brief annotations of 45 children's books inspired by children's curiosity. Presents the books in six categories: question and answer books, whodunit mysteries, mysteries of history, mysteries of nature, myths and legends, and mysteries of life. (SR)

  19. Media Type Influences Preschooler's Literacy Development: E-Book versus Printed Book Reading

    Science.gov (United States)

    Kozminsky, Ely; Asher-Sadon, Revital

    2013-01-01

    Traditionally, children's books are in a printed format and shared book reading is done with an adult. In recent years, interactive E-books have become a common medium for children's books and shared book reading is diminishing. This study compared the contribution of book format to the development of literacy in kindergarten children. We…

  20. Libros Bilingues, Traducciones y Libros Recomendables. (Bilingual Books, Translations and Recommended Books in Spanish.)

    Science.gov (United States)

    Taylor, Jose G., Comp.

    Citing 123 books published between 1960 and 1977, this bibliography is divided into 3 main categories: (1) books with Spanish and English text, (2) translations of books also available in English, and (3) recommended books in Spanish. The first two sections concentrate on books for use in grades K-3. The final section includes books for older…

  1. NEW VISIONS ON ELECTRONIC BOOKS

    OpenAIRE

    Vladimir Sulov

    2013-01-01

    At the beginning of the 21st century e-books gain an ever-increasing popularity as a substitute for conventional ones. At the same time the possibilities which new technologies offer lead to the development of the very essence of the e-book. In the article there is substantiated the need for and is proposed a new definition of the notion of “e-book”. There is outlined the process of the rise and improvement of e-books, the formats and devices for their reading, the connection between classica...

  2. Book Display as Adult Service

    Directory of Open Access Journals (Sweden)

    Matthew S. Moore

    1997-03-01

    Full Text Available 無Book display as an adult service is defined as choosing and positioning adult books from the collection to increase their circulation. The author contrasts bookstore arrangement for sales versus library arrangement for access. The paper considers the library-as-a-whole as a display, examines the right size for an in-library display, and discusses mass displays, end-caps, on-shelf displays, and the Tiffany approach. The author proposes that an effective display depends on an imaginative, unifying theme, and that book displays are part of the joy of libraries.

  3. Book review: Birds of Wyoming

    Science.gov (United States)

    Carr, N.B.

    2011-01-01

    "Wyoming may very well be one of the least birded states in the U.S." So begins this book, underscoring the challenges in summarizing existing knowledge for a state that falls next to last in human population density. Despite the relative dearth of "binoculars on the ground," especially in more remote areas of the state, the book offers a thorough compilation of relevant details. Much of this information is not readily accessible from other sources, and this book dispenses essential information in a very usable format. 

  4. BOOK REVIEW: Cosmology

    Science.gov (United States)

    Silk, Joseph

    2008-11-01

    recent, and comprehensive, is Cosmology, in which the University of Texas physicist and Nobel Laureate, Steven Weinberg provides a concise introduction to modern cosmology. The book is aimed at the level of a final year physics undergraduate, or a first year graduate student. The discussion is self-contained, with numerous derivations. It begins with an overview of the standard cosmological model, and presents a detailed treatment of fluctuation growth. There are sections on gravitational lensing and inflationary cosmology, on microwave background fluctuations and structure growth. There are aspects however where a supplementary book is essential for the physicist being introduced to cosmology. The text is lacking in physical cosmology. The baryon physics of galaxy formation is barely mentioned, apart from a discussion of the Jeans mass. And it ignores one of the greatest contributions to the field by Russian cosmologist Yaakov Zel'dovich, who discovered the only nonspherical solution to the nonlinear evolution of density fluctuations, one that has since dominated our understanding of the large-scale structure of the universe via the cosmic web. But these are minor quibbles about what provides an outstanding introduction to modern cosmology, and one that takes us from the physics fundamentals up to the cosmic frontier. I recommend Cosmology for anyone wishing to enter the field and with a good physics background. It is ideal for the astronomer who may only have a sketchy knowledge of general relativity or particle physics. She will learn about vielbeins and scalar fields, gauge-invariant fluctuation theory and inflation. Steven Weinberg is a leading physicist who has also made important contributions to cosmology. The text provides a rigorous treatment of the standard model of cosmology, and of structure formation. Numerous exercises are provided. It provides an excellent core for a course on cosmology.

  5. Keeping Pace: Science Trade Books in Spanish.

    Science.gov (United States)

    Schon, Isabel

    1985-01-01

    Describes elementary school science trade books written in Spanish. Topics considered in these books include: animal life; astronomy; biology; earth sciences; mathematics; general science; and general technology. (DH)

  6. Imprinting of Phenylalanine ethyl ester in cyclodextrin polymers in aqueous solution

    DEFF Research Database (Denmark)

    Detcheva, Anna Hr.; Yu, Donghong; Larsen, Kim Lambertsen

    During the last decades there has been a wide interest of developing molecularly imprinted polymers, which selectively can recognize small molecules. Cyclodextrins offer relatively strong binding site of a wide range of small molecules in water and molecular imprinted polymers of these have previ...

  7. Protein imprinting and recognition via forming nanofilms on microbeads surfaces in aqueous media

    Energy Technology Data Exchange (ETDEWEB)

    Lu Yan, E-mail: yanlu2001@sohu.com [College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007 (China); Yan Changling [College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007 (China); Wang Xuejing [Chemistry and Chemical Engineer School, Henna Institute of Science and Technology, Xinxiang 453003 (China); Wang Gongke [College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007 (China)

    2009-12-15

    In this paler, we present a technique of forming nanofilms of poly-3-aminophenylboronic acid (pAPBA) on the surfaces of polystyrene (PS) microbeads for proteins (papain and trypsin) in aqueous. Papain was chosen as a model to study the feasibility of the technique and trypsin as an extension. Obtained core-shell microbeads were characterized using scanning electron microscopy (SEM), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and BET methods. The results show that pAPBA formed nanofilms (60-100 nm in thickness) on the surfaces of PS microbeads. The specific surface area of the papain-imprinted beads was about 180 m{sup 2} g{sup -1} and its pore size was 31 nm. These imprinted microbeads exhibit high recognition specificity and fast mass transfer kinetics. The specificity of these imprinted beads mainly originates from the spatial effect of imprinted sites. Because the protein-imprinted sites were located at, or close to, the surface, the imprinted beads have good site accessibility toward the template molecules. The facility of the imprinting protocol and the high recognition properties of imprinted microbeads make the approach an attractive solution to problems in the field of biotechnology.

  8. Conserved imprinting associated with unique epigenetic signatures in the Arabidopsis genus.

    Science.gov (United States)

    Klosinska, Maja; Picard, Colette L; Gehring, Mary

    2016-01-01

    In plants, imprinted gene expression occurs in endosperm seed tissue and is sometimes associated with differential DNA methylation between maternal and paternal alleles(1). Imprinting is theorized to have been selected for because of conflict between parental genomes in offspring(2), but most studies of imprinting have been conducted in Arabidopsis thaliana, an inbred primarily self-fertilizing species that should have limited parental conflict. We examined embryo and endosperm allele-specific expression and DNA methylation genome-wide in the wild outcrossing species Arabidopsis lyrata. Here we show that the majority of A. lyrata imprinted genes also exhibit parentally biased expression in A. thaliana, suggesting that there is evolutionary conservation in gene imprinting. Surprisingly, we discovered substantial interspecies differences in methylation features associated with paternally expressed imprinted genes (PEGs). Unlike in A. thaliana, the maternal allele of many A. lyrata PEGs was hypermethylated in the CHG context. Increased maternal allele CHG methylation was associated with increased expression bias in favour of the paternal allele. We propose that CHG methylation maintains or reinforces repression of maternal alleles of PEGs. These data suggest that the genes subject to imprinting are largely conserved, but there is flexibility in the epigenetic mechanisms employed between closely related species to maintain monoallelic expression. This supports the idea that imprinting of specific genes is a functional phenomenon, and not simply a byproduct of seed epigenomic reprogramming.

  9. The Role of GNAS and Other Imprinted Genes in the Development of Obesity

    Science.gov (United States)

    Weinstein, Lee S.; Xie, Tao; Qasem, Ahmed; Wang, Jie; Chen, Min

    2010-01-01

    Genomic imprinting is an epigenetic phenomenon affecting a small number of genes which leads to differential expression from the two parental alleles. Imprinted genes are known to regulate fetal growth and a ‘kinship’ or ‘parental conflict’ model predicts that paternally- and maternally-expressed imprinted genes promote and inhibit fetal growth, respectively. In this review we examine the role of imprinted genes in postnatal growth and metabolism, with an emphasis on the GNAS/Gnas locus. GNAS is a complex imprinted locus with multiple oppositely imprinted gene products, including the G protein α-subunit Gsα which is expressed primarily from the maternal allele in some tissues and the Gsα isoform XLαs which is expressed only from the paternal allele. Maternal, but not paternal, Gsα mutations lead to obesity in Albright hereditary osteodystrophy. Mouse studies show that this phenomenon is due to Gsα imprinting in the central nervous system leading to a specific defect in the ability of central melanocortins to stimulate sympathetic nervous system activity and energy expenditure. In contrast mutation of paternally-expressed XLαs leads to opposite metabolic effects in mice. While these findings conform to the ‘kinship’ model, the effects of other imprinted genes on body weight regulation do not conform to this model. PMID:19844212

  10. EFFECTS OF PRIMARY IMPRINTING ON THE SUBSEQUENT DEVELOPMENT OF SECONDARY FILIAL ATTACHMENTS IN THE CHICK

    NARCIS (Netherlands)

    DEVOS, GJ; VANKAMPEN, HS

    1993-01-01

    This study reinvestigates the effects of primary imprinting of chicks with either a naturalistic stimulus or an artificial object on subsequent imprinting with artificial objects. Initial experience with a live chick (group C) or a yellow cylinder (group Y) had differential effects on the developmen

  11. Rapid Prototyping of Chemical Microsensors Based on Molecularly Imprinted Polymers Synthesized by Two-Photon Stereolithography.

    Science.gov (United States)

    Gomez, Laura Piedad Chia; Spangenberg, Arnaud; Ton, Xuan-Anh; Fuchs, Yannick; Bokeloh, Frank; Malval, Jean-Pierre; Tse Sum Bui, Bernadette; Thuau, Damien; Ayela, Cédric; Haupt, Karsten; Soppera, Olivier

    2016-07-01

    Two-photon stereolithography is used for rapid prototyping of submicrometre molecularly imprinted polymer-based 3D structures. The structures are evaluated as chemical sensing elements and their specific recognition properties for target molecules are confirmed. The 3D design capability is exploited and highlighted through the fabrication of an all-organic molecularly imprinted polymeric microelectromechanical sensor. PMID:27145145

  12. Charged hydrogels for post-loading, release, and molecular imprinting of proteins

    NARCIS (Netherlands)

    Schillemans, J.P.

    2010-01-01

    Molecular imprinting is a technique to create template-shaped cavities in polymer matrices with memory of the template molecules, to be used in molecular recognition. Molecular imprinting of low molecular weight compounds is a well established technique used to create high affinity materials. On the

  13. Synthesis, characterization and adsorption behavior of molecularly imprinted nanospheres for erythromycin using precipitation polymerization.

    Science.gov (United States)

    Kou, Xing; Lei, Jiandu; Geng, Liyuan; Deng, Hongquan; Jiang, Qiying; Zhang, Guifeng; Ma, Guanghui; Su, Zhiguo

    2012-09-01

    Preparation of uniform size molecularly imprinted nanospheres for erythromycin with good selectivity and high binding capacity by precipitation polymerization were presented, in which erythromycin, methacrylic acid and ethylene glycol dimethacrylate are used as template molecule, functional monomer and cross-linker, respectively. The synthesis conditions of molecularly imprinted nanospheres were optimized and the optimal molar ratio of erythromycin to functional monomer is 1:3. The molecularly imprinted polymers were characterized by scanning electron microscope, laser particle size analyzer and BET, respectively. The results suggested that molecularly imprinted nanospheres for erythromycin exhibited spherical shape and good monodispersity. Selectivity analysis indicated that the imprinted nanospheres could specifically recognize erythromycin from its structure analogues. Furthermore, adsorption kinetics and adsorption isotherm of the imprinted nanospheres were employed to investigate the binding characteristics of the imprinted nanospheres. The results showed that the imprinted nanospheres have high adsorption capacity for erythromycin, and the maximum theoretical static binding capacity is up to 267.0188 mg g(-1). PMID:23035481

  14. New generation ion-imprinted nanocarrier for removal of Cr(VI) from wastewater

    Energy Technology Data Exchange (ETDEWEB)

    Uygun, Murat, E-mail: muygun@adu.edu.tr [Adnan Menderes University, Kocarl Latin-Small-Letter-Dotless-I Vocational and Training School (Turkey); Feyzioglu, Esra; Oezcal Latin-Small-Letter-Dotless-I skan, Emir; Caka, Mueserref; Ergen, Aygen; Akgoel, Sinan [Ege University, Department of Biochemistry, Faculty of Science (Turkey); Denizli, Adil [Hacettepe University, Department of Chemistry, Faculty of Science (Turkey)

    2013-08-15

    The purpose of this study was to prepare a novel ion-imprinted nanoparticle to remove Cr(VI) ions from waste water. For this, Cr(VI) ions were complexed with 2-methacryloylamido histidine (MAH) and then Cr(VI)-imprinted poly(HEMAH) nanoparticles were synthesized by surfactant-free emulsion polymerization technique. The templates, Cr(VI) ions, were removed from the nanoparticles using 0.1 M of HNO{sub 3} solution. The specific surface area of the Cr(VI)-imprinted poly(HEMAH) nanoparticles was found to be 1,397.85 m{sup 2}/g, and the particle size was calculated as 155.3 nm. These Cr(VI)-imprinted nanoparticles were used for the adsorption/desorption of Cr(VI) ions from its aqueous solutions. The effects of initial Cr(VI) concentration and medium pH on the Cr(VI) adsorption capacity were also studied. The maximum adsorbed amount of Cr(VI) on the imprinted nanoparticles was found to be 3,830.58 mg/g nanoparticle in pH 4.0. In order to investigate the selectivity of the imprinted nanoparticle, adsorption studies were repeated using Cr(III) ions. The selectivity results demonstrated that Cr(VI)-imprinted poly(HEMAH) nanoparticles showed high affinity for the Cr(VI) ions than Cr(III). The Cr(VI)-imprinted nanoparticles were used several times without decreasing their Cr(VI) adsorption capacities.

  15. Protein imprinting and recognition via forming nanofilms on microbeads surfaces in aqueous media

    International Nuclear Information System (INIS)

    In this paler, we present a technique of forming nanofilms of poly-3-aminophenylboronic acid (pAPBA) on the surfaces of polystyrene (PS) microbeads for proteins (papain and trypsin) in aqueous. Papain was chosen as a model to study the feasibility of the technique and trypsin as an extension. Obtained core-shell microbeads were characterized using scanning electron microscopy (SEM), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and BET methods. The results show that pAPBA formed nanofilms (60-100 nm in thickness) on the surfaces of PS microbeads. The specific surface area of the papain-imprinted beads was about 180 m2 g-1 and its pore size was 31 nm. These imprinted microbeads exhibit high recognition specificity and fast mass transfer kinetics. The specificity of these imprinted beads mainly originates from the spatial effect of imprinted sites. Because the protein-imprinted sites were located at, or close to, the surface, the imprinted beads have good site accessibility toward the template molecules. The facility of the imprinting protocol and the high recognition properties of imprinted microbeads make the approach an attractive solution to problems in the field of biotechnology.

  16. Polycarbonate as an Elasto-Plastic Material Model for Simulation of the Microstructure Hot Imprint Process

    Directory of Open Access Journals (Sweden)

    Rokas Šakalys

    2013-08-01

    Full Text Available The thermal imprint process of polymer micro-patterning is widely applied in areas such as manufacturing of optical parts, solar energy, bio-mechanical devices and chemical chips. Polycarbonate (PC, as an amorphous polymer, is often used in thermoforming processes because of its good replication characteristics. In order to obtain replicas of the best quality, the imprint parameters (e.g., pressure, temperature, time, etc. must be determined. Therefore finite element model of the hot imprint process of lamellar periodical microstructure into PC has been created using COMSOL Multiphysics. The mathematical model of the hot imprint process includes three steps: heating, imprinting and demolding. The material properties of amorphous PC strongly depend on the imprint temperature and loading pressure. Polycarbonate was modelled as an elasto-plastic material, since it was analyzed below the glass transition temperature. The hot imprint model was solved using the heat transfer and the solid stress-strain application modes with thermal contact problem between the mold and polycarbonate. It was used for the evaluation of temperature and stress distributions in the polycarbonate during the hot imprint process. The quality of the replica, by means of lands filling ratio, was determined as well.

  17. Genomic Imprinting and the Expression of Affect in Angelman Syndrome: What's in the Smile?

    Science.gov (United States)

    Oliver, Chris; Horsler, Kate; Berg, Katy; Bellamy, Gail; Dick, Katie; Griffiths, Emily

    2007-01-01

    Background: Kinship theory (or the genomic conflict hypothesis) proposes that the phenotypic effects of genomic imprinting arise from conflict between paternally and maternally inherited alleles. A prediction arising for social behaviour from this theory is that imbalance in this conflict resulting from a deletion of a maternally imprinted gene,…

  18. Rapid Prototyping of Chemical Microsensors Based on Molecularly Imprinted Polymers Synthesized by Two-Photon Stereolithography.

    Science.gov (United States)

    Gomez, Laura Piedad Chia; Spangenberg, Arnaud; Ton, Xuan-Anh; Fuchs, Yannick; Bokeloh, Frank; Malval, Jean-Pierre; Tse Sum Bui, Bernadette; Thuau, Damien; Ayela, Cédric; Haupt, Karsten; Soppera, Olivier

    2016-07-01

    Two-photon stereolithography is used for rapid prototyping of submicrometre molecularly imprinted polymer-based 3D structures. The structures are evaluated as chemical sensing elements and their specific recognition properties for target molecules are confirmed. The 3D design capability is exploited and highlighted through the fabrication of an all-organic molecularly imprinted polymeric microelectromechanical sensor.

  19. MedPAC Data Book

    Data.gov (United States)

    U.S. Department of Health & Human Services — MedPACs Data Book is the result of discussions with congressional staff members regarding ways that MedPAC can better support them. Some of the information it...

  20. Books for the Job Hunt.

    Science.gov (United States)

    Saltzman, Amy

    1992-01-01

    Reviews new and classic titles on career choice, job search methods, executive/professional job search, resume writing, and interviewing. Advises avoiding books with simplistic formulas and exercises or overt sales pitches for software, videos, and other products. (SK)

  1. Book Reviews 2000-2001.

    Science.gov (United States)

    Grauer, Barbara Ellman, Ed.

    2001-01-01

    Contains reviews of 41 books on career management, job search strategies, entrepreneurship, the Internet job search, self-improvement; specific careers, women and careers, and career development e-business. Eight guides and workbooks are also reviewed. (JOW)

  2. Expression and imprinting of insulin-like growth factor II (IGF2) and H19 genes in uterine leiomyomas

    DEFF Research Database (Denmark)

    Rainho, C A; Pontes, A; Rogatto, S R

    1999-01-01

    Genomic imprinting is defined as a gamete of origin-specific epigenetic modification of DNA leading to differential gene expression in the zygote. Several imprinted genes have been identified and some of them are associated with tumor development. We investigated the expression and the imprinting...

  3. Short interspersed element (SINE) depletion and long interspersed element (LINE) abundance are not features universally required for imprinting.

    Science.gov (United States)

    Cowley, Michael; de Burca, Anna; McCole, Ruth B; Chahal, Mandeep; Saadat, Ghazal; Oakey, Rebecca J; Schulz, Reiner

    2011-04-20

    Genomic imprinting is a form of gene dosage regulation in which a gene is expressed from only one of the alleles, in a manner dependent on the parent of origin. The mechanisms governing imprinted gene expression have been investigated in detail and have greatly contributed to our understanding of genome regulation in general. Both DNA sequence features, such as CpG islands, and epigenetic features, such as DNA methylation and non-coding RNAs, play important roles in achieving imprinted expression. However, the relative importance of these factors varies depending on the locus in question. Defining the minimal features that are absolutely required for imprinting would help us to understand how imprinting has evolved mechanistically. Imprinted retrogenes are a subset of imprinted loci that are relatively simple in their genomic organisation, being distinct from large imprinting clusters, and have the potential to be used as tools to address this question. Here, we compare the repeat element content of imprinted retrogene loci with non-imprinted controls that have a similar locus organisation. We observe no significant differences that are conserved between mouse and human, suggesting that the paucity of SINEs and relative abundance of LINEs at imprinted loci reported by others is not a sequence feature universally required for imprinting.

  4. A Christmas Book from 1875

    Science.gov (United States)

    Greenslade, Thomas B., Jr.

    2009-01-01

    This is a story about a book that I found in my collection, its author, and the boy who owned it. The book is "The Boy's Playbook of Science", first published in 1860 by John Henry Pepper (1821-1900). On the flyleaf is written "Arthur G. Webster; Christmas/75; from Mama." Arthur Gordon Webster (1863-1923) was one of the founders of the American…

  5. Apple MacBook Air

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    当乔布斯手持MacBook Air,放言“there is somthing in air”时,苹果教徒们的信仰再一次得到了“升华”。其实再为MacBook Air来写这样一段文字,多少显得有些多余。

  6. Tv & video engineer's reference book

    CERN Document Server

    Jackson, K G

    1991-01-01

    TV & Video Engineer's Reference Book presents an extensive examination of the basic television standards and broadcasting spectrum. It discusses the fundamental concepts in analogue and digital circuit theory. It addresses studies in the engineering mathematics, formulas, and calculations. Some of the topics covered in the book are the conductors and insulators, passive components, alternating current circuits; broadcast transmission; radio frequency propagation; electron optics in cathode ray tube; color encoding and decoding systems; television transmitters; and remote supervision of unatten

  7. Google Books Bibliography, Version 6

    OpenAIRE

    Bailey, Jr., Charles W.

    2010-01-01

    This bibliography presents selected English-language articles and other works that are useful in understanding Google Books. It primarily focuses on the evolution of Google Books and the legal, library, and social issues associated with it. Where possible, links are provided to works that are freely available on the Internet, including e-prints in disciplinary archives and institutional repositories. Note that e-prints and published articles may not be identical. Bibliography versions are cum...

  8. Exploration Blueprint: Data Book

    Science.gov (United States)

    Drake, Bret G. (Editor)

    2007-01-01

    The material contained in this report was compiled to capture the work performed by the National Aeronautics and Space Administration's (NASA's) Exploration study team in the late 2002 timeframe. The "Exploration Blueprint Data Book" documents the analyses and findings of the 90-day Agency-wide study conducted from September - November 2002. During the summer of 2002, the NASA Deputy Administrator requested that a study be performed with the following objectives: (1) Develop the rationale for exploration beyond low-Earth orbit (2) Develop roadmaps for how to accomplish the first steps through humans to Mars (3) Develop design reference missions as a basis for the roadmaps 4) Make recommendations on what can be done now to effect this future This planning team, termed the Exploration Blueprint, performed architecture analyses to develop roadmaps for how to accomplish the first steps beyond LEO through the human exploration of Mars. The previous NASA Exploration Team activities laid the foundation and framework for development of NASA's Integrated Space Plan. The reference missions resulting from the analysis performed by the Exploration Blueprint team formed the basis for requirement definition, systems development, technology roadmapping, and risk assessments for future human exploration beyond low-Earth orbit. Emphasis was placed on developing recommendations on what could be done now to effect future exploration activities. The Exploration Blueprint team embraced the "Stepping Stone" approach to exploration where human and robotic activities are conducted through progressive expansion outward beyond low-Earth orbit. Results from this study produced a long-term strategy for exploration with near-term implementation plans, program recommendations, and technology investments. Specific results included the development of a common exploration crew vehicle concept, a unified space nuclear strategy, focused bioastronautics research objectives, and an integrated human

  9. Imprinted Polymeric Film-Based Sensor for the Detection of Dopamine Using Cyclic Voltammetry

    Institute of Scientific and Technical Information of China (English)

    郭洪声; 何锡文; 李一峻

    2003-01-01

    The imprinted polymeric film was synthesized on the glass-carbon electrodes dlrectly. The response to the template molecule-dopamine and other molecules with similar structure was measured by cyclic voltammetry. The response of dopamine on imprinted electrode was much higher than that of other molecules,because of the existing of micro-cavities in polymeric rdm fitting with the size and shape of dopamine in the imprinted polymer.Experimental results showed that dopamlne can be enriched by the imprinted film, therefore increasing the sensitivity of the sensor. The imprinted film could also efface the interference of ascorbic acid, indicating that dopamine can be determined with a large excess of ascorbic acid.

  10. Synthesis and characterization of oxytetracycline imprinted magnetic polymer for application in food

    Science.gov (United States)

    Aggarwal, Sneha; Rajput, Yudhishthir Singh; Singh, Gulab; Sharma, Rajan

    2016-02-01

    Magnetic imprinted polymer was prepared by polymerization of methacrylate and ethyleneglycoldimethacrylate in the presence of oxytetracycline on the surface of iron magnetite. Selectivity of prepared polymer was calculated from ratio of partition coefficient of oxytetracycline for imprinted and non- imprinted polymer in water, acetonitrile, methanol and at different pH in aqueous buffer. pH of solvent exhibited pronounced effect on selectivity. Selectivity at pH 7.0, 6.0 and 5.0 was 36.0, 2.25 and 1.61 fold higher than at pH 4.0. Imprinted polymer was not selective for oxytetracycline in methanol. However, selectivity in water and acetonitrile was 19.42 and 2.86, respectively. Oxytetracycline did bind to imprinted polymer in water or aqueous buffer (pH 7.0) and could be eluted with methanol. Prepared polymer extracted 75-80 % oxytetracycline from water, honey and egg white.

  11. Imprinting Analysis of the Porcine MEST Gene in 75 and 90 Day Placentas and Prenatal Tissues

    Institute of Scientific and Technical Information of China (English)

    Chenchang XU; Lijie SU; Quanyong ZHOU; Changchun LI; Shuhong ZHAO

    2007-01-01

    Imprinted genes play important roles in mammalian growth, development and behavior. Mouse mesoderm-specific transcript (MEST) has been identified as an imprinted gene and mapped to an imprinted region of mouse chromosome 6 (MMU6). It plays essential roles in embryonic and placental growth, and it is required for maternal behavior in adult female mouse. Here, we isolated the porcine MEST gene and detected a single nucleotide polymorphism in the 3'-untranslated region. The RsaI polymorphism was used to investigate the allele frequencies in different pig breeds and the imprinting status in prenatal porcine tissues.Allele frequencies were significantly different between the native Chinese and Landrace breeds, except that most of the native Yushan pigs (21/26) are heterozygous at this locus. The results indicate that MEST was imprinted in placentas on days 75 and 90 of gestation as well as in the 75 d fetal heart, muscle, kidney, lung and liver.

  12. Molecularly Imprinted Polymers: Thermodynamic and Kinetic Considerations on the Specific Sorption and Molecular Recognition

    Directory of Open Access Journals (Sweden)

    Kejun Tong

    2008-04-01

    Full Text Available This article presents a work aiming at thermodynamically and kinetically interpreting the specific sorption and recognition by a molecularly imprinted polymer. Using Boc-L-Phe-OH as a template, the imprinted material was prepared. The result indicates that the prepared polymer can well discriminate the imprint species from its analogue (Boc-D-Phe-OH, so as to adsorb more for the former but less for the latter. Kinetic analysis indicates that this specific sorption, in nature, can be a result of a preferential promotion. The imprint within the polymer causes a larger adsorption rate for the template than for the analogue. Thermodynamic study also implies that the molecular induction from the specific imprint to the template is larger than to the analogue, which thus makes the polymer capable of preferentially alluring the template to bind.

  13. Magnetic molecularly imprinted polydopamine nanolayer on multiwalled carbon nanotubes surface for protein capture.

    Science.gov (United States)

    Yin, Yuli; Yan, Liang; Zhang, Zhaohui; Wang, Jing

    2015-11-01

    A novel, facile and low cost process for imprinting protein on the surface of magnetic multiwalled carbon nanotubes (MMWNTs) was developed using human serum albumin (HSA) as the template and dopamine as the functional monomer. The magnetic imprinted polymers were characterized with transmission electron microscope (TEM), scanning electron microscope (SEM), Fourier-transform infrared spectrometry (FT-IR), vibrating sample magnetometer (VSM) and thermogravimetric analysis (TGA) in detail. The maximum adsorption capacity of the magnetic imprinted polymers toward HSA was 66.23 mg g(-1) and it took 20 min to achieve the adsorption equilibrium. The magnetic imprinted polymers exhibited the specific selective adsorption toward HSA. Coupled with high performance liquid chromatography (HPLC) analysis, the magnetic imprinted polymers were used to solid-phase extract and detect HSA in urine samples successfully with the recoveries of 91.95-97.8%.

  14. [Application of molecularly imprinted technology for separation of PGG from Guizhi Fuling capsule].

    Science.gov (United States)

    Song, Ya-ling; Wang, Xue-jing; Ni, Fu-yong; Gu, Rui; Zhao, Yi-wu; Huang, Wen-zhe; Wang, Zhen-zhong; Xu, Xiao-jie; Xiao, Wei

    2015-03-01

    1,2,3,4,6-penta-O-galloyl-D-glucose (PGG) is one of the main active compounds of Guizhi Fuling capsule. Molecularly imprinted polymers (MIP) have high affinity toward template molecules synthesized by molecularly imprinted technology for its specific combined sites, which can overcome the shortcoming of traditional separation methods, such as complex operation, low efficiency, using large quantity of solvent and environmental pollution. In this paper, surface molecularly imprinted polymer (SMIP) was prepared by surface imprinting with PGG as the template molecule. Its adsorption capacity was measured by the scatchard equation. The separation of PGG from Guizhi Fuling capsule at preparatived scale was achieved with molecularly imprinted polymer as stationary phase and the purity was 90.2% by HPLC. This method can be used to prepare PGG from Guizhi Fuling capsule with large capacity and is easy to operate. It provides a new method for efficient separation and purification for other natural products.

  15. Lsd1 and Lsd2 Control Programmed Replication Fork Pauses and Imprinting in Fission Yeast

    Directory of Open Access Journals (Sweden)

    Allyson Holmes

    2012-12-01

    Full Text Available In the fission yeast Schizosaccharomyces pombe, a chromosomal imprinting event controls the asymmetric pattern of mating-type switching. The orientation of DNA replication at the mating-type locus is instrumental in this process. However, the factors leading to imprinting are not fully identified and the mechanism is poorly understood. Here, we show that the replication fork pause at the mat1 locus (MPS1, essential for imprint formation, depends on the lysine-specific demethylase Lsd1. We demonstrate that either Lsd1 or Lsd2 amine oxidase activity is required for these processes, working upstream of the imprinting factors Swi1 and Swi3 (homologs of mammalian Timeless and Tipin, respectively. We also show that the Lsd1/2 complex controls the replication fork terminators, within the rDNA repeats. These findings reveal a role for the Lsd1/2 demethylases in controlling polar replication fork progression, imprint formation, and subsequent asymmetric cell divisions.

  16. A taste sensor based on surface imprinted TiO2 membrane

    Science.gov (United States)

    Xiao, Wenxiang; Chen, Zhencheng; Jiang, Xingguo; Zhao, Hongtian; Chu, Fugang; Hou, Hongbin

    2012-03-01

    Surface imprinted TiO2 membranes had been prepared and used as sensing membranes for basic tastes discrimination. Four basic taste molecules (citric acid, D-glucose, quinine hydrochloride and sodium L-glutamate for sour, sweet, bitter and umami respectively) were used as templates for imprinting. The sensor was fabricated in light-addressable potentiometric principle. Experimental results show that membranes imprinted by citric acid and quinine hydrochloride exhibit similar response behaviors towards four taste substances, that is citric acid > quinine hydrochloride > sodium L-glutamate > D-glucose. Membrane imprinted by sodium L-glutamate is sensitive towards quinine hydrochloride. Except for D-glucose imprinting membrane, other three membranes are inert to glucose. Combined with principal component analysis, four basic tastes can be well distinguished.

  17. GABA{sub A} receptor beta 3 subunit gene is possibly paternally imprinted in humans

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-02-15

    As the gene for GABA{sub A} receptor beta 3 subunit (GABRB3) is encompassed by a small molecular deletion in chromosome 15q11-q13, which is the critical region for Angelman syndrome(AS), the GABRB3 gene could be a candidate gene for AS. The abnormal phenotype of AS is manifested only when the deletion is inherited from the mother, not from the father. Therefore, a candidate gene for AS should be paternally imprinted. Although it was reported that the GABRB3 gene was expressed equally from either the maternal or paternal chromosome in mouse brain (i.e., not imprinted), it is well known that imprinting shows tissue specificity, and it remains to be determined if all genes imprinted in the mouse are also imprinted in humans. 4 refs., 1 fig.

  18. A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

    OpenAIRE

    Al Adhami, Hala; Evano, Brendan; Le Digarcher, Anne; Gueydan, Charlotte; Dubois, Emeric; Parrinello, Hugues; Dantec, Christelle; Bouschet, Tristan; Varrault, Annie; Journot, Laurent

    2015-01-01

    Genomic imprinting is an epigenetic mechanism that restrains the expression of ∼100 eutherian genes in a parent-of-origin-specific manner. The reason for this selective targeting of genes with seemingly disparate molecular functions is unclear. In the present work, we show that imprinted genes are coexpressed in a network that is regulated at the transition from proliferation to quiescence and differentiation during fibroblast cell cycle withdrawal, adipogenesis in vitro, and ...

  19. Imprinted and injection-molded nano-structured optical surfaces

    DEFF Research Database (Denmark)

    Christiansen, Alexander Bruun; Højlund-Nielsen, Emil; Clausen, Jeppe Sandvik;

    2013-01-01

    paper, nanostructured polymer surfaces suitable for up-scalable polymer replication methods, such as imprinting/embossing and injection-molding, are discussed. The limiting case of injection-moulding compatible designs is investigated. Anti-reflective polymer surfaces are realized by replication of...... of light from polymer surfaces and their implication for creating structural colors is discussed. In the case of injection-moulding compatible designs, the maximum reflection of nano-scale textured surfaces cannot exceed the Fresnel reflection of a corresponding flat polymer surface, which is approx...

  20. Frugal fat or munificent muscle: genomic imprinting and metabolism

    OpenAIRE

    Haig, David

    2014-01-01

    Variation in body composition is a popular obsession. The culturally ‘ideal’ body type is light on fat and heavy on muscle but the human population is collectively laying on fat. A new study finds antagonistic effects of two imprinted genes, Grb10 and Dlk1, on body composition in mice. These findings pose the question whether there is an evolutionary conflict between genes of maternal and paternal origin over the optimal proportions of body fat and lean muscle mass. See research article: http...

  1. A nano-scale alignment method for imprint lithography

    Institute of Scientific and Technical Information of China (English)

    WANG Li; LU Bing-heng; DING Yu-cheng; QIU Zhi-hui; LIU Hong-zhong

    2006-01-01

    A novel nano-scale alignment technique based generated by two pairs of quadruple gratings on mold and wafer are optically projected onto two photo-detector arrays,alignment errors in the x and y directions.The experiment sensitive to relative displacement of the mold and wafer,and the alignment accuracy obtained in the x and y directions and in θare ±20 nm,±25 nm and ±1 μrad (3σ),respectively.They can meet the requirements of alignment accuracy for submicron imprint lithography.

  2. Molecularly Imprinted Polymer Coated on Stainless Steel Fiber

    Institute of Scientific and Technical Information of China (English)

    Hu XiaoGang; Dai GuiMei; Huang JiaJing

    2009-01-01

    @@ With characteristics of specific selectivity,good chemical stability and easy preparation,molecularly imprinted polymer (MIP) has been used as the recognition materials m various fields ~([1,2]).Recently,the application of MIP in the sample pre-treatment techniques such as SPME was attractive ~([3,4]).For analysis of complicated samples,the interference matrix would be reduced obviously with the MIP-coated SPME fiber~([5-7]).Because MIPs were coated on the surface of silica fiber through chemical bonding,those fibers could be used for over 80 times without obvious losing of surface quality and extraction performance of MIP coatings.

  3. Molecular imprinted polypyrrole modified glassy carbon electrode for the determination of tobramycin

    International Nuclear Information System (INIS)

    Graphical abstract: Atomic force microscopic images of (A) bare GCE and (B) TOB imprinted PPy/GCE surface. - Highlights: • Glassy carbon electrode based on molecularly imprinted polypyrrole was prepared. • The developed surfaces were characterized by AFM, FTIR, EIS and CV. • The developed nanosensor was applied to egg and milk samples. - Abstract: Over the past two decades, molecular imprinted polymers have attracted a broad interest from scientists in sensor development. In the preparation of molecular imprinted polymers the desired molecule (template) induces the creation of specific recognition sites in the polymer. In this study, the glassy carbon electrode (GCE) based on molecularly imprinted polypyrrole (PPy) was fabricated for the determination of tobramycin (TOB). The developed electrode was prepared by incorporation of a template molecule (TOB) during the electropolymerization of pyrrole on GCE in aqueous solution using cyclic voltammetry (CV) method. The performance of the imprinted and non-imprinted electrodes was evaluated by square wave voltammetry (SWV). The effect of pH, monomer and template concentrations, electropolymerization cycles on the performance of the imprinted and non-imprinted electrodes was investigated and optimized. The non-modified and TOB-imprinted surfaces were characterized by using atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR), electrochemical impedance spectroscopy (EIS) and CV. The linearity range of TOB was 5.0 × 10−10–1.0 × 10−8 M with the detection limit of 1.4 × 10−10 M. The developed nanosensor was applied successfully for the determination of TOB in egg and milk

  4. A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation.

    Science.gov (United States)

    Al Adhami, Hala; Evano, Brendan; Le Digarcher, Anne; Gueydan, Charlotte; Dubois, Emeric; Parrinello, Hugues; Dantec, Christelle; Bouschet, Tristan; Varrault, Annie; Journot, Laurent

    2015-03-01

    Genomic imprinting is an epigenetic mechanism that restrains the expression of ∼ 100 eutherian genes in a parent-of-origin-specific manner. The reason for this selective targeting of genes with seemingly disparate molecular functions is unclear. In the present work, we show that imprinted genes are coexpressed in a network that is regulated at the transition from proliferation to quiescence and differentiation during fibroblast cell cycle withdrawal, adipogenesis in vitro, and muscle regeneration in vivo. Imprinted gene regulation is not linked to alteration of DNA methylation or to perturbation of monoallelic, parent-of-origin-dependent expression. Overexpression and knockdown of imprinted gene expression alters the sensitivity of preadipocytes to contact inhibition and adipogenic differentiation. In silico and in cellulo experiments showed that the imprinted gene network includes biallelically expressed, nonimprinted genes. These control the extracellular matrix composition, cell adhesion, cell junction, and extracellular matrix-activated and growth factor-activated signaling. These observations show that imprinted genes share a common biological process that may account for their seemingly diverse roles in embryonic development, obesity, diabetes, muscle physiology, and neoplasm.

  5. Appearance and functionality of electronic books: lessons from the visual book and hyper-textbook projects

    OpenAIRE

    Crestani, Fabio; Landoni, Monica; Melucci, Massimo

    2011-01-01

    We present the results and the lessons learned from two separate and independent studies into the design, development, and evaluation of electronic books for information access: the Visual Book and the Hyper-TextBook. The Visual Book explored the importance of the visual component of the book metaphor in the production of “good” electronic books for referencing. The Hyper-TextBook concentrated on the importance of models and techniques for the automatic production of functional electronic ...

  6. Examining Language of Information Books for Children

    Science.gov (United States)

    Inan, Hatice Zeynep

    2010-01-01

    In recent years, inclusion of information books in early childhood centers is well-advised since children show fast developing knowledge of information book language and enjoy reading those books. The aim of the current study is to discuss features of information books' language by examining the illustrations and texts of randomly selected 15…

  7. Advantages and Disadvantages of E-books

    Institute of Scientific and Technical Information of China (English)

    马立平

    2005-01-01

    The e-book has many advantages over a paperbased product. You can store lots of books on one computer—in fact your entire library could be stored on the top of your desk. E-books also allow you to mark your page with an electronic bookmark and jump straight to it when you open the book.

  8. Advantages and Disadvantages of E-books

    Institute of Scientific and Technical Information of China (English)

    马立平

    2004-01-01

    The e-book has many advantages over a paper-based product. You .can store lots of books on one computer-in fact your entire library could be stored on the top of your desk. E-books also allow you to mark your page with an electronic bookmark and jump straight to it when you open the book.

  9. Why Young Children Need Alphabet Books

    Science.gov (United States)

    Warner, Laverne; Weiss, Sara

    2005-01-01

    This article explains the importance of alphabet books in early reading development. Alphabet books encourage literacy development in the following ways: (1) unlock the symbols of language; (2) connect knowledge to other sources; (3) provide book usage knowledge to young children; (4) complement children's enjoyment of books; and (5) aid early…

  10. BSA-imprinted synthetic receptor for reversible template recognition.

    Science.gov (United States)

    Wang, Huafang; He, Yunhua; He, Xiwen; Li, Wenyou; Chen, Langxing; Zhang, Yukui

    2009-06-01

    A novel approach to the manufacturing of protein-responsive imprints on a home-made chitosan substrate was established together with m-aminophenylboronic acid (APBA) as a functional monomer. The produced polymers were characterized using both (1) equilibrium adsorption assays and (2) high performance liquid chromatography analysis. Results confirmed that the synthesized BSA-MIP (molecularly imprinted polymer) has a high affinity towards its template compared to the determined control proteins. The produced BSA-MIP featured largely in its good adsorption reversibility, especially in competitive binding assays, which is of great biological significance in separations. Non-specific binding was reduced to almost zero in a BSA/BHb competitive binding event. An excellent HPLC profile of template recognition was found for BSA-MIP, even under harsh mobile phase conditions. In the present work, the adopted trapped-template-release method permits recovery of bound BSA [1]. The strategy of making an artificial protein-receptor with high adsorption affinity and reversibility is promising in on-line isolation of target protein from complicated biological environments.

  11. Computational and experimental studies on oxalic acid imprinted polymer

    Indian Academy of Sciences (India)

    Kiran Kumar Tadi; R V Motghare

    2013-03-01

    Computational approach plays an important role to pre-evaluate the interactions between template and functional monomer, so that to choose functional monomer having stronger interactions with template during synthesis of molecularly imprinted polymers (MIPs). Hence template-monomer interactions in pre-polymerization were mainly focused. In this paper, computational chemistry was applied to screen the number of mol of functional monomer that interacts with one mol of template. Intermolecular interactions between oxalic acid and acrylamide have been investigated. The binding energies Ebind were calculated by DFT (B3LYP) level of theory with the 6−31+G(d,p) basis set. It was found that four mol of acrylamide were sufficient to interact with one mol of oxalic acid in the pre-polymerization mixture. Four possible conformations and frequency calculations were performed to locate minima. Oxalic acid specific bulk polymer was obtained by the thermal initiated free radical co-polymerization of acrylamide and ethylene glycol dimethacrylate with oxalic acid as template and acetonitrile as porogen. The synthesized MIP efficiently adsorbed oxalic acid from aqueous solutions. The binding parameters ofMIP and non-imprinted polymer (NIP) were compared by Freundlich and Langmuir adsorption isotherms.

  12. Molecularly imprinted hydrogels as functional active packaging materials.

    Science.gov (United States)

    Benito-Peña, Elena; González-Vallejo, Victoria; Rico-Yuste, Alberto; Barbosa-Pereira, Letricia; Cruz, José Manuel; Bilbao, Ainhoa; Alvarez-Lorenzo, Carmen; Moreno-Bondi, María Cruz

    2016-01-01

    This paper describes the synthesis of novel molecularly imprinted hydrogels (MIHs) for the natural antioxidant ferulic acid (FA), and their application as packaging materials to prevent lipid oxidation of butter. A library of MIHs was synthesized using a synthetic surrogate of FA, 3-(4-hydroxy-3-methoxyphenyl)propionic acid (HFA), as template molecule, ethyleneglycol dimethacrylate (EDMA) as cross-linker, and 1-allylpiperazine (1-ALPP) or 2-(dimethylamino)ethyl methacrylate (DMAEMA), in combination with 2-hydroxyethyl methacrylate (HEMA) as functional monomers, at different molar concentrations. The DMAEMA/HEMA-based MIHs showed the greatest FA loading capacity, while the 1-ALLP/HEMA-based polymers exhibited the highest imprinting effect. During cold storage, FA-loaded MIHs protected butter from oxidation and led to TBARs values that were approximately half those of butter stored without protection and 25% less than those recorded for butter covered with hydrogels without FA, potentially extending the shelf life of butter. Active packaging is a new field of application for MIHs with great potential in the food industry. PMID:26213001

  13. Electron beam inspection methods for imprint lithography at 32 nm

    Science.gov (United States)

    Selinidis, Kosta; Thompson, Ecron; Sreenivasan, S. V.; Resnick, Douglas J.

    2009-01-01

    Step and Flash Imprint Lithography redefines nanoimprinting. This novel technique involves the field-by-field deposition and exposure of a low viscosity resist deposited by jetting technology onto the substrate. The patterned mask is lowered into the fluid which then quickly flows into the relief patterns in the mask by capillary action. Following this filling step, the resist is crosslinked under UV radiation, and then the mask is removed leaving a patterned solid on the substrate. Compatibility with existing CMOS processes requires a mask infrastructure in which resolution, inspection and repair are all addressed. The purpose of this paper is to understand the limitations of inspection at half pitches of 32 nm and below. A 32 nm programmed defect mask was fabricated. Patterns included in the mask consisted of an SRAM Metal 1 cell, dense lines, and dense arrays of pillars. Programmed defect sizes started at 4 nm and increased to 48 nm in increments of 4 nm. Defects in both the mask and imprinted wafers were characterized scanning electron microscopy and the measured defect areas were calculated. These defects were then inspected using a KLA-T eS35 electron beam wafer inspection system. Defect sizes as small as 12 nm were detected, and detection limits were found to be a function of defect type.

  14. Selective sorption of perfluorooctane sulfonate on molecularly imprinted polymer adsorbents

    Institute of Scientific and Technical Information of China (English)

    Shubo DENG; Danmeng SHUAI; Qiang YU; Jun HUANG; Gang YU

    2009-01-01

    Perfluorooctane sulfonate (PFOS), as a potential persistent organic pollutant, has been widely detected in water environments, and has become a great concern in recent years. PFOS is very stable and difficult to decompose using conventional techniques. Sorption may be an attractive method to remove it from water. In this study, the molecularly imprinted polymer (MIP) adsorbents were prepared through the polymerization of 4-vinylpyridine under different preparation conditions in order to remove perfluorooctane sulfonate (PFOS) from water. The MIP adsorbents using perfluorooctanoic acid (PFOA) as the template had good imprinting effects and could selectively remove PFOS from aqueous solution. The sorption behaviors including sorption kinetics,isotherms, and effect of pH, salt, and competitive anions were investigated. Experimental results showed that the sorption of PFOS On the MIP adsorbents was very fast, pH-dependent, and highly selective. The achieved fast sorption equilibrium within 1 h was attributed to the surface sorption on the fine adsorbents. The sorption isotherms showed that the sorption selectivity of PFOS on the MIP adsorbents decreased at high PFOS concentrations, which may be due to the double-layer sorption and the formation of PFOS micelles on the sorbent surface. The sorption of PFOS on the MIP adsorbents was mainly dominated by the electrostatic interaction between the protonated vinylpyridine on the adsorbent surface and the anionic PFOS. The prepared MIP adsorbents can potentially be applied in water and wastewater treatment for selective removal of PFOS.

  15. Imprinting superconducting vortex footsteps in a magnetic layer

    Science.gov (United States)

    Brisbois, Jérémy; Motta, Maycon; Avila, Jonathan I.; Shaw, Gorky; Devillers, Thibaut; Dempsey, Nora M.; Veerapandian, Savita K. P.; Colson, Pierre; Vanderheyden, Benoît; Vanderbemden, Philippe; Ortiz, Wilson A.; Nguyen, Ngoc Duy; Kramer, Roman B. G.; Silhanek, Alejandro V.

    2016-06-01

    Local polarization of a magnetic layer, a well-known method for storing information, has found its place in numerous applications such as the popular magnetic drawing board toy or the widespread credit cards and computer hard drives. Here we experimentally show that a similar principle can be applied for imprinting the trajectory of quantum units of flux (vortices), travelling in a superconducting film (Nb), into a soft magnetic layer of permalloy (Py). In full analogy with the magnetic drawing board, vortices act as tiny magnetic scribers leaving a wake of polarized magnetic media in the Py board. The mutual interaction between superconducting vortices and ferromagnetic domains has been investigated by the magneto-optical imaging technique. For thick Py layers, the stripe magnetic domain pattern guides both the smooth magnetic flux penetration as well as the abrupt vortex avalanches in the Nb film. It is however in thin Py layers without stripe domains where superconducting vortices leave the clearest imprints of locally polarized magnetic moment along their paths. In all cases, we observe that the flux is delayed at the border of the magnetic layer. Our findings open the quest for optimizing magnetic recording of superconducting vortex trajectories.

  16. Imprinting superconducting vortex footsteps in a magnetic layer

    Science.gov (United States)

    Brisbois, Jérémy; Motta, Maycon; Avila, Jonathan I.; Shaw, Gorky; Devillers, Thibaut; Dempsey, Nora M.; Veerapandian, Savita K. P.; Colson, Pierre; Vanderheyden, Benoît; Vanderbemden, Philippe; Ortiz, Wilson A.; Nguyen, Ngoc Duy; Kramer, Roman B. G.; Silhanek, Alejandro V.

    2016-01-01

    Local polarization of a magnetic layer, a well-known method for storing information, has found its place in numerous applications such as the popular magnetic drawing board toy or the widespread credit cards and computer hard drives. Here we experimentally show that a similar principle can be applied for imprinting the trajectory of quantum units of flux (vortices), travelling in a superconducting film (Nb), into a soft magnetic layer of permalloy (Py). In full analogy with the magnetic drawing board, vortices act as tiny magnetic scribers leaving a wake of polarized magnetic media in the Py board. The mutual interaction between superconducting vortices and ferromagnetic domains has been investigated by the magneto-optical imaging technique. For thick Py layers, the stripe magnetic domain pattern guides both the smooth magnetic flux penetration as well as the abrupt vortex avalanches in the Nb film. It is however in thin Py layers without stripe domains where superconducting vortices leave the clearest imprints of locally polarized magnetic moment along their paths. In all cases, we observe that the flux is delayed at the border of the magnetic layer. Our findings open the quest for optimizing magnetic recording of superconducting vortex trajectories. PMID:27263660

  17. Will E-books change the world?

    OpenAIRE

    Hillesund, Terje

    2001-01-01

    This paper argues that the evolution of e-book technology is related to the penetrating impact of networks and information technology on society. It defines the concept of e-book and describes some aspects of e-book technology. By focusing on book production processes, the paper examines what probable consequences the development of e-books and a global network economy will have for publishers and book industries. E-books, along with other electronic formats, will trigger major changes as the...

  18. The library beyond the book

    CERN Document Server

    Schnapp, Jeffrey T

    2014-01-01

    With textbook readers and digital downloads proliferating, it is easy to imagine a time when printed books will vanish. Such forecasts miss the mark, argue Jeffrey Schnapp and Matthew Battles. Future bookshelves will not be wholly virtual, and libraries will thrive although in a variety of new social, cultural, and architectural forms. Schnapp and Battles combine deep study of the library s history with a record of institutional and technical innovation at metaLAB, a research group at the forefront of the digital humanities. They gather these currents in The Library Beyond the Book," exploring what libraries have been in the past to speculate on what they will become: hybrid places that intermingle books and ebooks, analog and digital formats, paper and pixels. Libraries have always been mix-and-match spaces, and remix is their most plausible future scenario. Speculative and provocative, The Library Beyond the Book" explains book culture for a world where the physical and the virtual blend with ever increasin...

  19. Variable allelic expression of imprinted genes in human pluripotent stem cells during differentiation into specialized cell types in vitro.

    Science.gov (United States)

    Park, Sang-Wook; Kim, Jihoon; Park, Jong-Lyul; Ko, Ji-Yun; Im, Ilkyun; Do, Hyo-Sang; Kim, Hyemin; Tran, Ngoc-Tung; Lee, Sang-Hun; Kim, Yong Sung; Cho, Yee Sook; Lee, Dong Ryul; Han, Yong-Mahn

    2014-04-01

    Genomic imprinting is an epigenetic phenomenon by which a subset of genes is asymmetrically expressed in a parent-of-origin manner. However, little is known regarding the epigenetic behaviors of imprinted genes during human development. Here, we show dynamic epigenetic changes in imprinted genes in hESCs during in vitro differentiation into specialized cell types. Out of 9 imprinted genes with single nucleotide polymorphisms, mono-allelic expression for three imprinted genes (H19, KCNQ1OT1, and IPW), and bi- or partial-allelic expression for three imprinted genes (OSBPL5, PPP1R9A, and RTL1) were stably retained in H9-hESCs throughout differentiation, representing imprinting stability. Three imprinted genes (KCNK9, ATP10A, and SLC22A3) showed a loss and a gain of imprinting in a lineage-specific manner during differentiation. Changes in allelic expression of imprinted genes were observed in another hESC line during in vitro differentiation. These findings indicate that the allelic expression of imprinted genes may be vulnerable in a lineage-specific manner in human pluripotent stem cells during differentiation.

  20. Explicit horizontal open books on some plumbings

    OpenAIRE

    Etgü, Tolga; Ozbagci, Burak

    2005-01-01

    We describe explicit open books on arbitrary plumbings of oriented circle bundles over closed oriented surfaces. We show that, for a non-positive plumbing, the open book we construct is horizontal and the corresponding compatible contact structure is also horizontal and Stein fillable. In particular, we describe horizontal open books on some Seifert fibered 3--manifolds. As another application we describe horizontal open books isomorphic to Milnor open books for some complex surface singulari...

  1. Recommender system for Slovene electronic books

    OpenAIRE

    Žitnik, Lovro

    2016-01-01

    The thesis describes a prototype of recommender system for Slovenian e-library. Data includes multitude of books in the ePub format, anonymized list of users and a set of transactions between the books and users. Book content was tokenized, POS-tagged and lemmatized. Data extraction methods were used to extract numerical stylometric features of books. Features were evaluated with SPEC and Laplacian scores. We reduced dimensionality of feature vectors of both books and users and clustered them...

  2. Electronic Study Books and learning style

    OpenAIRE

    De Diana, I.P.F.; Heiden, van der, G.

    1994-01-01

    Attention has been drawn to the concepts of Electronic Books and Electronic Study Books. Several publications have discussed some main ideas (paradigms) for both concepts. For the Electronic Study Book as a learning environment, it is essential to consider individual modes of learning, usually termed 'learning styles'. It is argued that Electronic Study Books should be adaptable in accordance with personal learning styles. Some options will be presented to link 'styles' and 'books'. One such ...

  3. Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective.

    Directory of Open Access Journals (Sweden)

    Brian DeVeale

    Full Text Available In contrast to existing estimates of approximately 200 murine imprinted genes, recent work based on transcriptome sequencing uncovered parent-of-origin allelic effects at more than 1,300 loci in the developing brain and two adult brain regions, including hundreds present in only males or females. Our independent replication of the embryonic brain stage, where the majority of novel imprinted genes were discovered and the majority of previously known imprinted genes confirmed, resulted in only 12.9% concordance among the novel imprinted loci. Further analysis and pyrosequencing-based validation revealed that the vast majority of the novel reported imprinted loci are false-positives explained by technical and biological variation of the experimental approach. We show that allele-specific expression (ASE measured with RNA-Seq is not accurately modeled with statistical methods that assume random independent sampling and that systematic error must be accounted for to enable accurate identification of imprinted expression. Application of a robust approach that accounts for these effects revealed 50 candidate genes where allelic bias was predicted to be parent-of-origin-dependent. However, 11 independent validation attempts through a range of allelic expression biases confirmed only 6 of these novel cases. The results emphasize the importance of independent validation and suggest that the number of imprinted genes is much closer to the initial estimates.

  4. Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective.

    Science.gov (United States)

    DeVeale, Brian; van der Kooy, Derek; Babak, Tomas

    2012-01-01

    In contrast to existing estimates of approximately 200 murine imprinted genes, recent work based on transcriptome sequencing uncovered parent-of-origin allelic effects at more than 1,300 loci in the developing brain and two adult brain regions, including hundreds present in only males or females. Our independent replication of the embryonic brain stage, where the majority of novel imprinted genes were discovered and the majority of previously known imprinted genes confirmed, resulted in only 12.9% concordance among the novel imprinted loci. Further analysis and pyrosequencing-based validation revealed that the vast majority of the novel reported imprinted loci are false-positives explained by technical and biological variation of the experimental approach. We show that allele-specific expression (ASE) measured with RNA-Seq is not accurately modeled with statistical methods that assume random independent sampling and that systematic error must be accounted for to enable accurate identification of imprinted expression. Application of a robust approach that accounts for these effects revealed 50 candidate genes where allelic bias was predicted to be parent-of-origin-dependent. However, 11 independent validation attempts through a range of allelic expression biases confirmed only 6 of these novel cases. The results emphasize the importance of independent validation and suggest that the number of imprinted genes is much closer to the initial estimates. PMID:22479196

  5. Retinoblastoma and its binding partner MSI1 control imprinting in Arabidopsis.

    Directory of Open Access Journals (Sweden)

    Pauline E Jullien

    2008-08-01

    Full Text Available Parental genomic imprinting causes preferential expression of one of the two parental alleles. In mammals, differential sex-dependent deposition of silencing DNA methylation marks during gametogenesis initiates a new cycle of imprinting. Parental genomic imprinting has been detected in plants and relies on DNA methylation by the methyltransferase MET1. However, in contrast to mammals, plant imprints are created by differential removal of silencing marks during gametogenesis. In Arabidopsis, DNA demethylation is mediated by the DNA glycosylase DEMETER (DME causing activation of imprinted genes at the end of female gametogenesis. On the basis of genetic interactions, we show that in addition to DME, the plant homologs of the human Retinoblastoma (Rb and its binding partner RbAp48 are required for the activation of the imprinted genes FIS2 and FWA. This Rb-dependent activation is mediated by direct transcriptional repression of MET1 during female gametogenesis. We have thus identified a new mechanism required for imprinting establishment, outlining a new role for the Retinoblastoma pathway, which may be conserved in mammals.

  6. Magnetic deep eutectic solvents molecularly imprinted polymers for the selective recognition and separation of protein.

    Science.gov (United States)

    Liu, Yanjin; Wang, Yuzhi; Dai, Qingzhou; Zhou, Yigang

    2016-09-14

    A novel and facile magnetic deep eutectic solvents (DES) molecularly imprinted polymers (MIPs) for the selective recognition and separation of Bovine hemoglobin (BHb) was prepared. The new-type DES was adopted as the functional monomer which would bring molecular imprinted technology to a new direction. The amounts of DES were optimized. The obtained magnetic DES-MIPs were characterized with fourier transform infrared spectrometry (FT-IR), thermogravimetric analysis (TGA), field emission scanning electron microscope (FESEM), dynamic light scattering (DLS), elemental analysis and vibrating sample magnetometer (VSM). The results suggested that the imprinted polymers were successfully formed and possessed a charming magnetism. The maximum adsorption capability (Qmax) and dissociation constant (KL) were analyzed by Langmuir isotherms (R(2) = 0.9983) and the value were estimated to be 175.44 mg/g and 0.035 mg/mL for the imprinted particles. And the imprinted particles showed a high imprinting factor of 4.77. In addition, the magnetic DES-MIPs presented outstanding recognition specificity and selectivity so that it can be utilized to separate template protein from the mixture of proteins and real samples. Last but not least, the combination of deep eutectic solvents and molecular imprinted technology in this paper provides a new perspective for the recognition and separation of proteins. PMID:27566352

  7. Preparation of novel bovine hemoglobin surface-imprinted polystyrene nanoparticles with magnetic susceptibility

    Institute of Scientific and Technical Information of China (English)

    LI Lin; HE XiWen; CHEN LangXing; ZHANG YuKui

    2009-01-01

    In this research,a surface imprinting strategy has been adopted in protein imprinting.Bovine hemoglobin surface-imprinted polystyrene (PS) nanoparticles with magnetic susceptibility have been synthesized through multistage core-shell polymerization system using 3-aminophenylboronic acid (APBA)as functional and cross-linking monomers.SuperparamagneUc molecularly imprinted polystyrene nanospheres with poly(APBA) thin films have been synthesized and used for the first time for protein molecular imprinting in an aqueous solution.The magnetic susceptibility is imparted through the successful encapsulation of Fe3O4 nanoparticles.The morphology,adsorption,and recognition properties of superparamagnetic molecularly imprinted polymers (MIPs) have been investigated using transmission electron microscopy,X-ray diffraction,thermogravimetric analysis,and vibrating sample magnetometer.Rebinding experimental results show that poly(APBA) MIPs-coated superparamagnetic PS nanoparticles have high adsorption capacity for template protein bovine hemoglobin and comparatively low nonspecific adsorption.The imprinted superparamagnetlc nanoparticles could easily reach the adsorption equilibrium and achieve magnetic separation in an external magnetic field,thus avoiding some problems of the bulk polymer.

  8. Effect of template on chiral separation of phenylalanine using molecularly imprinted membrane in aqueous medium

    International Nuclear Information System (INIS)

    Wet phase inversion method was used to prepare L-Phenylalanine (L-Phe) and D-Phenylalanine (D-Phe) imprinted poly ((acrylonitrile)-co-(acrylic acid)) membranes for chiral separation. Ultrafiltration experiments were conducted to evaluate the chiral separation ability of the prepared membrane towards racemate aqueous solution of Phenylalanine. The continuous permselectivity was observed by novel membrane. The chiral resolution ability of L-Phe imprinted membrane was much better than that of D-Phe. It was observed that both membranes simultaneously, selectively reject, selectively adsorbed and selectively permeate solute. The achieved adsorption selectivities of L-Phe imprinted membrane (AlphaAds)L and D-Phe imprinted membrane (AlphaAds)D were 2.6 and 2.40 respectively. Permselectivity of L-Phe imprinted membrane (AlphaPerm)L was 2.56 while D-Phe imprinted membrane permselectivity (AlphaPerm)D was 2.03. The rejection selectivities of L-Phe and D-Phe imprinted membranes were (AlphaRej)L=0.32 and (AlphaRej)D =0.28 respectively. (author)

  9. Imprinted Genes and the Environment: Links to the Toxic Metals Arsenic, Cadmium and Lead

    Directory of Open Access Journals (Sweden)

    Lisa Smeester

    2014-06-01

    Full Text Available Imprinted genes defy rules of Mendelian genetics with their expression tied to the parent from whom each allele was inherited. They are known to play a role in various diseases/disorders including fetal growth disruption, lower birth weight, obesity, and cancer. There is increasing interest in understanding their influence on environmentally-induced disease. The environment can be thought of broadly as including chemicals present in air, water and soil, as well as food. According to the Agency for Toxic Substances and Disease Registry (ATSDR, some of the highest ranking environmental chemicals of concern include metals/metalloids such as arsenic, cadmium, lead and mercury. The complex relationships between toxic metal exposure, imprinted gene regulation/expression and health outcomes are understudied. Herein we examine trends in imprinted gene biology, including an assessment of the imprinted genes and their known functional roles in the cell, particularly as they relate to toxic metals exposure and disease. The data highlight that many of the imprinted genes have known associations to developmental diseases and are enriched for their role in the TP53 and AhR pathways. Assessment of the promoter regions of the imprinted genes resulted in the identification of an enrichment of binding sites for two transcription factor families, namely the zinc finger family II and PLAG transcription factors. Taken together these data contribute insight into the complex relationships between toxic metals in the environment and imprinted gene biology.

  10. Preparation of novel bovine hemoglobin surface-imprinted polystyrene nanoparticles with magnetic susceptibility

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this research, a surface imprinting strategy has been adopted in protein imprinting. Bovine hemo-globin surface-imprinted polystyrene (PS) nanoparticles with magnetic susceptibility have been syn-thesized through multistage core-shell polymerization system using 3-aminophenylboronic acid (APBA) as functional and cross-linking monomers. Superparamagnetic molecularly imprinted polystyrene nanospheres with poly(APBA) thin films have been synthesized and used for the first time for protein molecular imprinting in an aqueous solution. The magnetic susceptibility is imparted through the successful encapsulation of Fe3O4 nanoparticles. The morphology, adsorption, and recognition prop-erties of superparamagnetic molecularly imprinted polymers (MIPs) have been investigated using transmission electron microscopy, X-ray diffraction, thermogravimetric analysis, and vibrating sample magnetometer. Rebinding experimental results show that poly(APBA) MIPs-coated superparamagnetic PS nanoparticles have high adsorption capacity for template protein bovine hemoglobin and compara-tively low nonspecific adsorption. The imprinted superparamagnetic nanoparticles could easily reach the adsorption equilibrium and achieve magnetic separation in an external magnetic field, thus avoid-ing some problems of the bulk polymer.

  11. Targeting and Imaging of Cancer Cells via Monosaccharide-Imprinted Fluorescent Nanoparticles

    Science.gov (United States)

    Wang, Shuangshou; Yin, Danyang; Wang, Wenjing; Shen, Xiaojing; Zhu, Jun-Jie; Chen, Hong-Yuan; Liu, Zhen

    2016-03-01

    The recognition of cancer cells is a key for cancer diagnosis and therapy, but the specificity highly relies on the use of biorecognition molecules particularly antibodies. Because biorecognition molecules suffer from some apparent disadvantages, such as hard to prepare and poor storage stability, novel alternatives that can overcome these disadvantages are highly important. Here we present monosaccharide-imprinted fluorescent nanoparticles (NPs) for targeting and imaging of cancer cells. The molecularly imprinted polymer (MIP) probe was fluorescein isothiocyanate (FITC) doped silica NPs with a shell imprinted with sialic acid, fucose or mannose as the template. The monosaccharide-imprinted NPs exhibited high specificity toward the target monosaccharides. As the template monosaccharides used are over-expressed on cancer cells, these monosaccharide-imprinted NPs allowed for specific targeting cancer cells over normal cells. Fluorescence imaging of human hepatoma carcinoma cells (HepG-2) over normal hepatic cells (L-02) and mammary cancer cells (MCF-7) over normal mammary epithelial cells (MCF-10A) by these NPs was demonstrated. As the imprinting approach employed herein is generally applicable and highly efficient, monosaccharide-imprinted NPs can be promising probes for targeting cancer cells.

  12. Development of a biosensor for detection of pleural mesothelioma cancer biomarker using surface imprinting.

    Directory of Open Access Journals (Sweden)

    Aabhas Mathur

    Full Text Available Hyaluronan-linked protein 1 (HAPLN1 which has been shown to be highly expressed in malignant pleural mesotheliomas (MPM, was detected in serum using an electrochemical surface-imprinting method. First, the detection method was optimized using Bovine serum albumin (BSA as a model protein to mimic the optimal conditions required to imprint the similar molecular weight protein HAPLN1. BSA was imprinted on the gold electrode with hydroxyl terminated alkane thiols, which formed a self-assembled monolayer (SAM around BSA. The analyte (BSA was then washed away and its imprint (empty cavity with shape-memory was used for detection of BSA in a solution, using electrochemical open-circuit potential method, namely potentiometry. Factors considered to optimize the conditions include incubation time, protein concentration, limit of detection and size of electrode. Matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS was used to confirm selectivity of imprints. With the obtained imprinting control parameters, HAPLN1 was imprinted in duplicate and the detection of spiked HAPLN1 was successfully conducted in serum.

  13. Imprinting modulates processing of visual information in the visual wulst of chicks

    Directory of Open Access Journals (Sweden)

    Uchimura Motoaki

    2006-11-01

    Full Text Available Abstract Background Imprinting behavior is one form of learning and memory in precocial birds. With the aim of elucidating of the neural basis for visual imprinting, we focused on visual information processing. Results A lesion in the visual wulst, which is similar functionally to the mammalian visual cortex, caused anterograde amnesia in visual imprinting behavior. Since the color of an object was one of the important cues for imprinting, we investigated color information processing in the visual wulst. Intrinsic optical signals from the visual wulst were detected in the early posthatch period and the peak regions of responses to red, green, and blue were spatially organized from the caudal to the nasal regions in dark-reared chicks. This spatial representation of color recognition showed plastic changes, and the response pattern along the antero-posterior axis of the visual wulst altered according to the color the chick was imprinted to. Conclusion These results indicate that the thalamofugal pathway is critical for learning the imprinting stimulus and that the visual wulst shows learning-related plasticity and may relay processed visual information to indicate the color of the imprint stimulus to the memory storage region, e.g., the intermediate medial mesopallium.

  14. Controlling size and uniformity of molecularly imprinted nanoparticles using auxiliary template.

    Science.gov (United States)

    Chen, Zhiyong; Ye, Lei

    2012-06-01

    Molecularly imprinted nanomaterials are gaining substantial importance. As a simple and efficient synthetic method, precipitation polymerization has been used to prepare uniform molecularly imprinted microspheres for numerous template compounds. Despite of its general applicability, the difficulty of obtaining uniform particles for some difficult templates by precipitation polymerization has been reported. In this work, we attempted to produce uniform atrazine-imprinted nanoparticles using propranolol as an auxiliary template under standard precipitation polymerization condition. When propranolol was added in the prepolymerization mixture for atrazine imprinting, it displayed a significant effect on particle size and size distribution of atrazine-imprinted polymers. The molecular binding characteristics of the molecularly imprinted polymer (MIP) nanoparticles were found to be dependent on the relative ratios of the two templates. Under an optimal template propranolol-atrazine ratio of 1:3 mol/mol, very uniform imprinted nanoparticles (d(H)  = 106 nm) with a polydispersity index of 0.07 were obtained. The loading of the auxiliary template (propranolol) could be reduced to as low as 5% without sacrificing the uniformity of the MIP nanoparticles. The uniform MIP nanoparticles could be easily encapsulated into polyethylene terephthalate nanofibers using a simple electrospinning technique. The composite nanofibers containing the MIP nanoparticles maintained specific molecular binding capability for both atrazine and propranolol.

  15. Molecularly imprinted titania nanoparticles for selective recognition and assay of uric acid

    Science.gov (United States)

    Mujahid, Adnan; Khan, Aimen Idrees; Afzal, Adeel; Hussain, Tajamal; Raza, Muhammad Hamid; Shah, Asma Tufail; uz Zaman, Waheed

    2015-06-01

    Molecularly imprinted titania nanoparticles are su ccessfully synthesized by sol-gel method for the selective recognition of uric acid. Atomic force microscopy is used to study the morphology of uric acid imprinted titania nanoparticles with diameter in the range of 100-150 nm. Scanning electron microscopy images of thick titania layer indicate the formation of fine network of titania nanoparticles with uniform distribution. Molecular imprinting of uric acid as well as its subsequent washing is confirmed by Fourier transformation infrared spectroscopy measurements. Uric acid rebinding studies reveal the recognition capability of imprinted particles in the range of 0.01-0.095 mmol, which is applicable in monitoring normal to elevated levels of uric acid in human blood. The optical shift (signal) of imprinted particles is six times higher in comparison with non-imprinted particles for the same concentration of uric acid. Imprinted titania particles have shown substantially reduced binding affinity toward interfering and structurally related substances, e.g. ascorbic acid and guanine. These results suggest the possible application of titania nanoparticles in uric acid recognition and quantification in blood serum.

  16. CERN scientific book fair 2010

    CERN Multimedia

    CERN Library

    2010-01-01

    The CERN Bookshop and CERN Library invite you to attend the 2010 CERN Book Fair, a two-day scientific event offering you the opportunity to meet key publishers and to browse and purchase books at significant discounts.   Some twelve companies will be present and will bring with them a selection of titles in physics, technology, mathematics, engineering, computing and popular science. You are welcome to come along and meet the publishers’ representatives or simply have a look to the books on offer. The Fair will take place in the Main Building (bldg. 500) on the ground floor near the Restaurant 1 on Tuesday 7th and Wednesday 8th September. Participating or represented publishers include: Cambridge University Press, EPFL Press – PPUR, Oxford University Press, Imperial College Press, McGraw-Hill, Oxford University Press, Pearson Education, Princeton University Press, Springer, Taylor and Francis, Wiley, World Scientific. Fair opening times: Tuesday 7 September 9:00 &ndash...

  17. CERN Scientific Book Fair 2013

    CERN Multimedia

    CERN Library

    2013-01-01

    The CERN Bookshop and CERN Library invite you to attend the 2013 CERN Book Fair, a two-day scientific event offering you the opportunity to meet key publishers and to browse and purchase books at significant discounts.   Key publishers will present a selection of titles in physics, technology, mathematics, engineering, computing and popular science. You are welcome to come along and meet the publishers’ representatives or simply have a look at the books on sale. The fair will take place in the Main Building (Bldg. 500) on the ground floor near Restaurant 1 on Monday 9 and Tuesday 10 September. Participating or represented publishers include: Oxford University Press, Princeton University Press, Springer, Wiley, and World Scientific-Imperial College Press. Fair opening times:  - Monday 9 September 9:00 - 18:00  - Tuesday 10 September 9:00 - 18:00

  18. MacBook portable genius

    CERN Document Server

    Miser, Brad

    2008-01-01

    The Genius is in. You don't have to be a genius to use a MacBook. But if you want to get the very most out of yours, put this savvy Portable Genius guide to work. Want to connect your MacBook to other Macs? Use Expose to its fullest potential? Troubleshoot? You'll find cool and useful Genius tips, insider secrets, full-color screenshots, and pages of easy-to-access shortcuts and tools that will save you loads of time and make your MacBook IQ soar. Portable GENIUS Fun, hip, and straightforward, the new Portable Genius series gives forward-thinking Apple users useful informat

  19. Imprint cytology on microcalcifications excised by Vacuum-Assisted Breast Biopsy: A rapid preliminary diagnosis

    Science.gov (United States)

    Fotou, Maria; Oikonomou, Vassiliki; Zagouri, Flora; Sergentanis, Theodoros N; Nonni, Afroditi; Athanassiadou, Pauline; Drouveli, Theodora; atsouris, Efstratios; Kotzia, Evagelia; Zografos, George C

    2007-01-01

    Background To evaluate imprint cytology in the context of specimens with microcalcifications derived from Vacuum-Assisted Breast Biopsy (VABB). Patients and methods A total of 93 women with microcalcifications BI-RADS 3 and 4 underwent VABB and imprint samples were examined. VABB was performed on Fischer's table using 11-gauge Mammotome vacuum probes. A mammogram of the cores after the procedure confirmed the excision of microcalcifications. For the application of imprint cytology, the cores with microcalcifications confirmed by mammogram were gently rolled against glass microscope slides and thus imprint smears were made. For rapid preliminary diagnosis Diff-Quick stain, modified Papanicolaou stain and May Grunwald Giemsa were used. Afterwards, the core was dipped into a CytoRich Red Collection fluid for a few seconds in order to obtain samples with the use of the specimen wash. After the completion of cytological procedures, the core was prepared for routine histological study. The pathologist was blind to the preliminary cytological results. The cytological and pathological diagnoses were comparatively evaluated. Results According to the pathological examination, 73 lesions were benign, 15 lesions were carcinomas (12 ductal carcinomas in situ, 3 invasive ductal carcinomas), and 5 lesions were precursor: 3 cases of atypical ductal hyperplasia (ADH) and 2 cases of lobular neoplasia (LN). The observed sensitivity and specificity of the cytological imprints for cancer were 100% (one-sided, 97.5% CI: 78.2%–100%). Only one case of ADH could be detected by imprint cytology. Neither of the two LN cases was detected by the imprints. The imprints were uninformative in 11 out of 93 cases (11.8%). There was no uninformative case among women with malignancy. Conclusion Imprint cytology provides a rapid, accurate preliminary diagnosis in a few minutes. This method might contribute to the diagnosis of early breast cancer and possibly attenuates patients' anxiety. PMID

  20. Genome-wide analysis reveals a complex pattern of genomic imprinting in mice.

    Directory of Open Access Journals (Sweden)

    Jason B Wolf

    2008-06-01

    Full Text Available Parent-of-origin-dependent gene expression resulting from genomic imprinting plays an important role in modulating complex traits ranging from developmental processes to cognitive abilities and associated disorders. However, while gene-targeting techniques have allowed for the identification of imprinted loci, very little is known about the contribution of imprinting to quantitative variation in complex traits. Most studies, furthermore, assume a simple pattern of imprinting, resulting in either paternal or maternal gene expression; yet, more complex patterns of effects also exist. As a result, the distribution and number of different imprinting patterns across the genome remain largely unexplored. We address these unresolved issues using a genome-wide scan for imprinted quantitative trait loci (iQTL affecting body weight and growth in mice using a novel three-generation design. We identified ten iQTL that display much more complex and diverse effect patterns than previously assumed, including four loci with effects similar to the callipyge mutation found in sheep. Three loci display a new phenotypic pattern that we refer to as bipolar dominance, where the two heterozygotes are different from each other while the two homozygotes are identical to each other. Our study furthermore detected a paternally expressed iQTL on Chromosome 7 in a region containing a known imprinting cluster with many paternally expressed genes. Surprisingly, the effects of the iQTL were mostly restricted to traits expressed after weaning. Our results imply that the quantitative effects of an imprinted allele at a locus depend both on its parent of origin and the allele it is paired with. Our findings also show that the imprinting pattern of a locus can be variable over ontogenetic time and, in contrast to current views, may often be stronger at later stages in life.

  1. Imprint cytology on microcalcifications excised by Vacuum-Assisted Breast Biopsy: A rapid preliminary diagnosis

    Directory of Open Access Journals (Sweden)

    Drouveli Theodora

    2007-04-01

    Full Text Available Abstract Background To evaluate imprint cytology in the context of specimens with microcalcifications derived from Vacuum-Assisted Breast Biopsy (VABB. Patients and methods A total of 93 women with microcalcifications BI-RADS 3 and 4 underwent VABB and imprint samples were examined. VABB was performed on Fischer's table using 11-gauge Mammotome vacuum probes. A mammogram of the cores after the procedure confirmed the excision of microcalcifications. For the application of imprint cytology, the cores with microcalcifications confirmed by mammogram were gently rolled against glass microscope slides and thus imprint smears were made. For rapid preliminary diagnosis Diff-Quick stain, modified Papanicolaou stain and May Grunwald Giemsa were used. Afterwards, the core was dipped into a CytoRich Red Collection fluid for a few seconds in order to obtain samples with the use of the specimen wash. After the completion of cytological procedures, the core was prepared for routine histological study. The pathologist was blind to the preliminary cytological results. The cytological and pathological diagnoses were comparatively evaluated. Results According to the pathological examination, 73 lesions were benign, 15 lesions were carcinomas (12 ductal carcinomas in situ, 3 invasive ductal carcinomas, and 5 lesions were precursor: 3 cases of atypical ductal hyperplasia (ADH and 2 cases of lobular neoplasia (LN. The observed sensitivity and specificity of the cytological imprints for cancer were 100% (one-sided, 97.5% CI: 78.2%–100%. Only one case of ADH could be detected by imprint cytology. Neither of the two LN cases was detected by the imprints. The imprints were uninformative in 11 out of 93 cases (11.8%. There was no uninformative case among women with malignancy. Conclusion Imprint cytology provides a rapid, accurate preliminary diagnosis in a few minutes. This method might contribute to the diagnosis of early breast cancer and possibly attenuates

  2. The web designer's idea book

    CERN Document Server

    Mcneil, Patrick

    Inspiring Web Design at a GlanceThe Web Designer's Idea Book includes more than 700 websites arranged thematically, so you can find inspiration for layout, color, style and more. Author Patrick McNeil has cataloged more than 5,000 sites on his website, and showcased in this book are the very best examples.Sites are organized by type, design style, theme, color, element and structure. Each chapter is easy to use and reference again and again, whether you're talking with a coworker or discussing website design options with a client. As a handy desk reference for design layout, color and style, t

  3. Writing the Live Coding Book

    DEFF Research Database (Denmark)

    Cox, Geoff; Blackwell, Alan; Lee, Sang Wong

    2016-01-01

    This paper is a speculation on the relationship between coding and writing, and the ways in which technical innovations and capabilities enable us to rethink each in terms of the other. As a case study, we draw on recent experiences of preparing a book on live coding, which integrates a wide range...... of personal, historical, technical and critical perspectives. This book project has been both experimental and reflective, in a manner that allows us to draw on critical understanding of both code and writing, and point to the potential for new practices in the future....

  4. OCR additional mathematics practice book

    CERN Document Server

    Hanrahan, Val

    2013-01-01

    Complete support for the bestselling textbook with hundreds of questions, enabling students to practise and consolidate what they have learnt throughout the course. This practice book:. - Develops students' skills and helps them prepare effectively for the exam with graduated questions, including harder exam-style questions- Helps students to recall what they have learnt with Key Points at the start of each Practice Book chapter- Builds students' confidence and helps them tackle harder problems, with access to short hints when needed- Indicates which formulae the students will need for each ch

  5. Google Books - Abzocken mit Rechtsbeistand

    OpenAIRE

    Gerhard Ruiss

    2010-01-01

    Wie sieht es eigentlich mit den Rechten bei "Google Books" aus? Vor rund einem Jahr wurden zum ersten Mal die Pläne von Google zur Veröffentlichung aller jemals erschienenen Bücher auf der Internetplattform "Google Book Search" bzw. mittlerweile "Google Bücher" auch außerhalb der USA bekannt. Bis zu diesem Zeitpunkt hielt man in den meisten anderen Ländern den Konflikt amerikanischer Autoren und Verlage mit dem US-Netzdienstleister "Google" über die Veröffentlichungsrechte für einen inner...

  6. Google Book Search解读

    Institute of Scientific and Technical Information of China (English)

    徐翠艳

    2008-01-01

    Google公司推行的Coogle Book Search引起了社会各界的强烈反响,出版商、图书馆、著作者、读者各执一词,争执激烈.从它的运行模式、可行性、可能遇到的障碍等方面入手,系统分析Goosle Book Search的推广前景以及时图书馆的影响,具有一定的现实意义.

  7. Children's Books about Math: Trade Books That Teach.

    Science.gov (United States)

    Murphy, Stuart J.

    2000-01-01

    Argues that math stories engage children and connect mathematical ideas to students' own personal experiences; that such books provide learning opportunities for children with different learning styles; and that children advance not only their mathematics skills but their critical thinking, language arts, and comprehension skills through such…

  8. The I Hate Mathematics! Book. A Brown Paper School Book.

    Science.gov (United States)

    Burns, Marilyn

    This 1975 book is written for children who do not like mathematics and presents activities which may help them to begin understanding mathematics. Activities are organized under the following headings: "Street Math"; "Maybe Grownups Aren't as Smart as You Think"; "Things to Do When You Have the Flu"; "A Math-Magic Show"; "How to Always Be a…

  9. Children's Books in Review: Expand Kids' Knowledge with Nonfiction Books.

    Science.gov (United States)

    Winfield, Evelyn T.

    1991-01-01

    Examines several current nonfiction books that can expand a child's knowledge of a wide variety of subjects, noting that the breadth of a child's knowledge base affects his or her reading development. Subjects discussed include dinosaurs, animal preservation, insects, ecology, history, and drugs and alcohol. (SM)

  10. Astronomical Books and Charts in the Book of Bibliographie Coreenne

    Science.gov (United States)

    Lee, Ki-Won; Yang, Hong-Jin; Park, Myeong-Gu

    2008-06-01

    We investigate astronomical materials listed in the book of Bibliographie Coréenne written by Maurice Courant. He classified ancient Korean books into nine Divisions (?) and thirty six Classes (?), and published them as three volumes (ranging from 1894 to 1896) and one supplement (in 1901). In total, 3,821 books including astronomical ones are listed together with information on physical size, possessional place, bibliographical note, and so forth. Although this book is an essential one in the field of Korea bibliography and contains many astronomical materials such as Cheon-Mun-Ryu-Cho ????, Si-Heon-Seo ??????, and Cheon-Sang-Yeol-Cha-Bun-Ya-Ji-Do ????????, it has not been well known to the public nor to astronomical society. Of 3,821 catalogues, we found that about 50 Items (?) are related to astronomy or astrology, and verified that most ! of them are located in the Kyujanggak Royal Library ???. We also found an unknown astronomical chart, Hon-Cheon-Chong-Seong-Yeol-Cha-Bun-Ya-Ji-Do ??????????. Because those astronomical materials are not well known to international astronomical community and there have been few studies on the materials in Korea, we here introduce and review them, particularly with the astronomical viewpoint.

  11. The English Book Club (or, The Book Lives On)

    CERN Multimedia

    2008-01-01

    The English Book Club was one of the first clubs to be founded at CERN. Since the late 1950s it has been a literary lifeline for English speakers in a predominantly French-speaking environment. The English Book Club has moved once again, and now has its home in Hut 564. Earlier lodgings included the fire station (remember "Fahrenheit 451") and the basement of Building 3, where it got flooded (shades of "Robinson Crusoe")."When people arrive in this country, they often feel a bit lost," explains Adam Park, who is in charge of the club’s communications. "Finding the club makes them feel at home. That’s why we have members from other international organisations, too." In the old days, of course, merely obtaining a book in English could be difficult. While it’s become much easier, thanks to specialty bookstores in Geneva, and of course the Internet, books remain an expensive item. For those looking for one of the great classics, th...

  12. Studies on the synthesis and properties of malachite green imprinted polymer

    Institute of Scientific and Technical Information of China (English)

    Li Qiang Su; Shi Qiao; Wei Bing Zhang

    2007-01-01

    A new molecularly imprinted polymer was synthesized with malachite green (MG) as molecular template, methacrylic acid(MAA) as functional monomer, ethylene dimethacrylate (EDMA) as crosslinker, and azobisisobutyronitrile (AIBN) as initiator.Recognition properties of the MG imprinted polymer were studied by equilibrium adsorption and HPLC. The results showed that the imprinted polymer had good affinity and marked selectivity for MG, and can separate MG with its analogue commendably. The new polymer can be used for the enrichment of MG in complex sample, and can work as separation media to separate and detect MG by HPLC.

  13. Imprint Lithography at Room Temperature with Novolak Resin and Its Application

    Institute of Scientific and Technical Information of China (English)

    T.Numai

    2007-01-01

    1 Results Imprint lithography[1] has attracted considerable attention from the viewpoint of low cost fabrication,because light exposure systems are not required. Up to now,polymethylmethacrylate (PMMA) films and hard molds were often used in imprint lithography.In this paper,we report on the successful demonstration of imprint lithography using novolak resin (OFPR-800),which is more suitable than PMMA for dry etching,and a soft mold such as a soft polyester sheet,which has a two-dimensional (2D) square ...

  14. Identification of the Imprinted KLF14 Transcription Factor Undergoing Human-Specific Accelerated Evolution

    OpenAIRE

    Layla Parker-Katiraee; Carson, Andrew R; Takahiro Yamada; Philippe Arnaud; Robert Feil; Abu-Amero, Sayeda N; Moore, Gudrun E.; Masahiro Kaneda; Perry, George H.; Stone, Anne C.; Charles Lee; Makiko Meguro-Horike; Hiroyuki Sasaki; Keiko Kobayashi; Kazuhiko Nakabayashi

    2007-01-01

    Imprinted genes are expressed in a parent-of-origin manner and are located in clusters throughout the genome. Aberrations in the expression of imprinted genes on human Chromosome 7 have been suggested to play a role in the etiologies of Russell-Silver Syndrome and autism. We describe the imprinting of KLF14, an intronless member of the Krüppel-like family of transcription factors located at Chromosome 7q32. We show that it has monoallelic maternal expression in all embryonic and extra-embryon...

  15. A non-destructive metrology solution for detailed measurements of imprint templates and media

    Science.gov (United States)

    Roberts, Jeffrey; Hu, Linlin; Eriksson, Torbjörn; Thulin, Kristian; Heidari, Babak

    2009-10-01

    This study investigates a non-destructive optical metrology technique, that furnishes measurement solutions for hard drive discrete track recording (DTR) and bit patterned media (BPM) templates and imprints. From the measurement and analysis of polarized reflectance and transmittance, feature height and profile of DTR and BPM templates and imprints, as well as residual layer thickness of imprints, are accurately determined, and uniformity maps of these parameters are produced in a fraction of a minute. Simulations of theoretical polarized reflectance and transmittance, relating to next generation structures, demonstrate that the optical metrology solution has capability for future products.

  16. Chemically Modified Chitosan Beads as Molecularly Imprinted Polymer Matrix for Adsorptive Separation of Proteins

    Institute of Scientific and Technical Information of China (English)

    Tian Ying GUO; Yong Qing XIA; Guang Jie HAO; Bang Hua ZHANG

    2004-01-01

    In a phosphate buffer, a hemoglobin (Hb)-imprinted polymer complex was prepared using maleic anhydride (MAH) modified chitosan beads as matrix, acrylamide (AM) as functional monomer, N,N-methylenebisacrylamide (MBA) as cross-linker and potassiumpersulfate (KPS)/sodium hydrogen sulfite (NaHSO3) as initiators. Langmuir analysis showed that an equal class of adsorption was formed in the molecular imprinting polymer (MIP), and the MIP has high adsorption capacity and selectivity for the imprinted molecule. The MIP can be reused and the recovery was approximately 100% at low concentration.

  17. Molecularly Imprinted Polymer with Calix[4]arene Derivative for the Recognition of Acetanilide

    Institute of Scientific and Technical Information of China (English)

    LU, Chun-Yang(卢春阳); HE, Hai-Cheng(何海成); HE, Xi-Wen(何锡文); ZENG, Xian-Shun(曾宪顺)

    2004-01-01

    Two molecularly imprinted polymers binding to analgesic acetanilide were prepared using either dual functional monomers of calix[4]arene derivative and acrylamide or single monomer acrylamide, respectively. The polymers were ground, sieved and investigated by equilibrium binding experiment to evaluate their recognition properties for the template and other substrates. Scatchard analysis showed that homogeneous recognition sites were formed in the imprinted polymer matrix. Our results demonstrated that the polymer using two functional monomers exhibited better selectivity for the template. This study may open new frontiers for the development and application of imprinted polymers, such as drug separation and purification.

  18. Methylation of DNA is an epigenetic modification critical for gametic imprinting

    Directory of Open Access Journals (Sweden)

    Marta Olszewska

    2010-12-01

    Full Text Available Differences in epigenetic patterns in male and female organisms highlight the key role of epigenetic mechanisms in development, initiated in gametogenesis. A consequence of imprinting is the expression of only one allele – maternal or paternal. Disturbances in imprinting cause genetic disorders (e.g., Angelman syndrome, Prader-Willi syndrome, Beckwith-Wiedemann syndrome, Silver-Russell syndrome or influence cancer development. Also immature gametes used in artificial reproductive technologies may increase the risk of genetic disorders in offspring. Imprinting is heritable and does not change during the lifetime of an organism.

  19. Google Books - Abzocken mit Rechtsbeistand

    Directory of Open Access Journals (Sweden)

    Gerhard Ruiss

    2010-03-01

    Full Text Available Wie sieht es eigentlich mit den Rechten bei "Google Books" aus? Vor rund einem Jahr wurden zum ersten Mal die Pläne von Google zur Veröffentlichung aller jemals erschienenen Bücher auf der Internetplattform "Google Book Search" bzw. mittlerweile "Google Bücher" auch außerhalb der USA bekannt. Bis zu diesem Zeitpunkt hielt man in den meisten anderen Ländern den Konflikt amerikanischer Autoren und Verlage mit dem US-Netzdienstleister "Google" über die Veröffentlichungsrechte für einen inneramerikanischen Streit. Erst durch die gerichtliche Anordnung des mit der Streitbeilegung beschäftigten New Yorker Richters Denny Chin zur weltweiten Bekanntmachung der konkreten Pläne von Google im Februar 2009 zeigte sich das gesamte Ausmaß der Absichten Googles. Google hatte in einem gerichtlichen Vergleichsdokument ("Google Book Settlement", das von Chin genehmigt werden sollte, sämtliche im Buchhandel erhältliche und in Bibliotheken archivierte Buchtitel weltweit aufgelistet, um sie nach gerichtlicher Genehmigung im Volltext in seinem Büchersuchdienst abrufbar zu machen. Inklusive weiterer Veröffentlichungen und Verbreitungen der Bücher zu seinem Nutzen und Gewinn wie u.a. durch Downloads, Print-On-Demand-Ausgaben, E-Books, Datenbank-Einspeisungen u.v.a.m.

  20. Cutting edge intermediate : student's book

    CERN Document Server

    Cunningham, Sarah

    2004-01-01

    A focus on high-frequency useful vocabulary helps students say what they want to say. Regular, well-structured speaking tasks encourage students to express themselves more extensively and fluently. ‘Do You Remember’ sections in every unit and extra. Consolidation modules provide regular review and consolidation Student Books include Mini-Dictionary to help learners study independently.