WorldWideScience

Sample records for bolsters

  1. Zika Connection to Rare Nerve Disorder Bolstered by Study

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_161325.html Zika Connection to Rare Nerve Disorder Bolstered by Study ... has developed the strongest evidence to date that Zika virus can cause a rare nerve disorder called ...

  2. Mechanically Powered Negative Pressure Wound Therapy as a Bolster for Skin Grafting

    Directory of Open Access Journals (Sweden)

    Adam L. Isaac, DPM

    2014-02-01

    Full Text Available Summary: The use of negative pressure wound therapy (NPWT as a bolster for split-thickness skin grafts has been well documented in the literature. It facilitates the removal of transudate, which can result in the formation of seroma, and mitigates shear stress, which can detach the graft from the underlying wound bed. Its widespread use may be limited by factors such as increased cost and length of hospitalization. Recently, mechanically powered devices (Smart Negative Pressure; Spiracur, Inc., Sunnyvale, Calif. have been reported as showing promise in healing wounds with outcomes surprisingly comparable to standard NPWT in the populations studied. We are unaware of any reports in the literature that have detailed the use of a mechanically powered NPWT device as a postoperative bolster for split-thickness skin grafts.

  3. Mechanically Powered Negative Pressure Wound Therapy as a Bolster for Skin Grafting

    OpenAIRE

    Adam L. Isaac, DPM; Jessica Rose, DO; David G. Armstrong, DPM, MD, PhD

    2014-01-01

    Summary: The use of negative pressure wound therapy (NPWT) as a bolster for split-thickness skin grafts has been well documented in the literature. It facilitates the removal of transudate, which can result in the formation of seroma, and mitigates shear stress, which can detach the graft from the underlying wound bed. Its widespread use may be limited by factors such as increased cost and length of hospitalization. Recently, mechanically powered devices (Smart Negative Pressure; Spiracur, In...

  4. Research and Teaching: Think before (and after) You Speak: Practice and Self-Reflection Bolster Oral Communication Skills

    Science.gov (United States)

    Sterling, Eleanor; Bravo, Adriana; Porzecanski, Ana Luz; Burks, Romi L.; Linder, Joshua; Langen, Tom; Fernandez, Denny; Ruby, Douglas; Bynum, Nora

    2016-01-01

    In this study, conservation biology faculty and practitioners from across the United States designed classroom exercises and teaching interventions intended to bolster oral communication skills. Through repeated oral presentation assignments integrated into course requirements, the authors examined individual student learning gains via…

  5. In the midst of a large measles outbreak, EDs take steps to bolster screening procedures, prevent potential transmissions.

    Science.gov (United States)

    2015-04-01

    A large, multi-state outbreak of measles is prompting EDs around the country to bolster their screening procedures and provide education to staff, most of whom have never seen a measles case. Dozens of people in more than 17 states have been confirmed to have the disease, with most of these cases associated with an outbreak that began at an amusement park in southern California. Measles is extremely contagious, infecting nine out of 10 people exposed to the virus if they are susceptible to the disease. In cases in which a contagious disease is suspected, experts advise emergency providers to protect themselves before proceeding to the traditional vital signs. It's a concept referred to as "vital sign zero." Once a measles case is confirmed, experts say emergency staff should isolate the patient with protection such as an N-95 mask, and inform both the hospital's infection control department and public health authorities.

  6. Moderating Risks, Bolstering Growth

    OpenAIRE

    World Bank

    2012-01-01

    Half a year ago, Russia's economic prospects looked uncertain. The global economy was losing momentum, the expansion in the euro area was grinding to a halt and commodity prices were beginning to fall. Yet, while output growth is slowing this year in line with weaker growth in Europe and elsewhere, Russia's latest economy performance has been solid, though aided by favorable oil prices. Th...

  7. New TRIUMF bolsters Canadian physics

    CERN Multimedia

    Gwynne, P

    2001-01-01

    Alan Shotter has been appointed director of TRIUMF. The ISAC accelerator there will be used to simulate astrophysical phenomena but the director will also be looking at ways to expand the research programme into other areas (1/2 page).

  8. China to Bolster Oil Stockpiles

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ China is accelerating the build-up of its oil reserves to avoid the economic dislocations the country suffered in 2008 from fluctuations in the world oil price.China will,in addition to the current four strategic petroleum reserve bases,build eight new ones by 2011.The program will increase China's strategic crude reserve capacity to 44.6 million cubic meters,or 281 million barrels.The country will also increase its oil products reserve to 10 million tons by 2011."China's attentiveness to its oil reserve capacity has grown in tandem with its rising dependence on imported oil," said Pan Jiahua,an expert with the Chinese petroleum society.

  9. Landsat helps bolster food security

    Science.gov (United States)

    U.S. Geological Survey

    2016-01-01

    One of the cruelest, most complex narratives in the world today (2016) is written in the hunger of sub-Saharan Africa. When famine is the only yield from the scorched Earth, survival often depends on a heart-rending calculation—how far is the distant feeding center; how close is the nearest well.

  10. Landsat helps bolster food security

    Science.gov (United States)

    ,

    2016-08-24

    One of the cruelest, most complex narratives in the world today (2016) is written in the hunger of sub-Saharan Africa. When famine is the only yield from the scorched Earth, survival often depends on a heart-rending calculation—how far is the distant feeding center; how close is the nearest well.

  11. Child Care Gifts to Bolster Astronomy

    Science.gov (United States)

    Nemiroff, Robert J.; Allen, Alice

    2016-01-01

    Caring for children should not derail potentially excellent future astronomers. It is therefore suggested that a mechanism be created for established astronomers to voluntarily will 10 percent of their estate to a fund that helps aspiring astronomers reduce child care costs. Statistics indicate that many scientists delay child rearing until they have secure jobs. This delay appears to be based on the early relative cost of child care and the perception that time spent raising children negatively impacts job performance and future employability. Having even a portion of child care expenses covered may increase the efficiency of early-career education and productivity of early-career scientific research. It is hoped that some established astronomers may be inspired to contribute by remembering their own lives as aspiring astronomers, while also wishing to add to their legacy. Only an expression of interest is requested here, both from established astronomers who might be interested in taking such a donation pledge, and from aspiring astronomers who feel their careers would be helped by child care assistance.

  12. Bolstering the U.S.Middle Class

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Making every attempt to boost the sluggish U.S.economy, U.S.President Barack Obama has pledged incentive programs including tax cuts for the middle class that have "for generations,made our economy the envy of the world." But the program may not be a panacea as income inequality in the United States becomes entrenched.Zhang Monan,a researcher with the State Information Center,discussed this issue in an article recently published in the China Securities Journal.Edited excerpts follow.

  13. Dengue Virus May Bolster Zika's Attack

    Science.gov (United States)

    ... dengue fever virus may increase the severity of Zika virus, a new study says. Early stage laboratory findings ... Services, or federal policy. More Health News on: Zika Virus Recent Health News Related MedlinePlus Health Topics Dengue ...

  14. FDA Bolsters Warnings about Class of Antibiotics

    Science.gov (United States)

    ... and benefits of fluoroquinolones and make an informed decision about their use," Cox said. A safety review revealed that potentially permanent side effects involving tendons, muscles, joints, nerves and the central nervous system can occur ...

  15. Russian energy in the EU market: Bolstered institutionsand their effects

    International Nuclear Information System (INIS)

    The article examines institutional changes in EU–Russian energy relations since 2000. The article explores the ability of transformed institutions to limit the politicisation of energy and to reconcile the EU competitive-market approach with Russian state capitalism. More specifically, the article focuses on changes in intergovernmental, transgovernmental and transnational interactions. The article demonstrates that the gradual strengthening of transgovernmental and transnational institutions has inhibited the politicisation of energy relations and facilitated regulative cooperation between the EU and Russia. However, the potential of shared institutions is constrained by internal institutions on both sides. In Russia, these obstacles are insufficient top-down delegation of responsibilities in the government and its great power aspirations. In the EU, key barriers include inter-institutional rivalries, the EU’s propensity to impose its legislation on external partners and the integration of energy policy with foreign policy. The article presents several policy implications. First, it is futile to institutionally impose the regulative paradigm of one partner on the other; rather, mutual dialogue is needed. Thus, institutions should be structured appropriately. Second, current depoliticisation will require the involvement of not only the EU and Russia but also transit countries, such as Ukraine. Third, transgovernmental and transnational cooperation should be nurtured because this is a useful channel for both information exchange and a regulative convergence of policy implementing mechanisms. Finally, this incremental regulative convergence is the only option available today for the EU and Russia; this is also a way to further depoliticise energy relations. - Highlights: • EU and Russia developed transgovernmental and transnational energy institutions. • It allowed them to face energy challenges: depoliticisation and market construction. • Internal EU and Russian institutions act as constraints. • Institutions have to marry Russia's state capitalism and EU competitive markets. • Transgovernmental and transnational institutions are to be further promoted

  16. Time will tell: resource continuity bolsters ecosystem services.

    Science.gov (United States)

    Schellhorn, Nancy A; Gagic, Vesna; Bommarco, Riccardo

    2015-09-01

    A common suggestion to support ecosystem services to agriculture provided by mobile organisms is to increase the amount of natural and seminatural habitat in the landscape. This might, however, be inefficient, and demands for agricultural products limit the feasibility of converting arable land into natural habitat. To develop more targeted means to promote ecosystem services, we need a solid understanding of the limitations to population growth for service-providing organisms. We propose a research agenda that identifies resource bottlenecks and interruptions over time to key beneficial organisms, emphasising their resulting population dynamics. Targeted measures that secure the continuity of resources throughout the life cycle of service-providing organisms are likely to effectively increase the stock, flow, and stability of ecosystem services. PMID:26138384

  17. Bolstering the Impact of Online Professional Development for Teachers

    Science.gov (United States)

    Reeves, Todd D.; Pedulla, Joseph J.

    2013-01-01

    Online professional development (OPD) for teachers is an increasingly popular and viable alternative to face-to-face professional development. While OPD can be effective, little is known about OPD's design and implementation features that maximize its impact. Using data from a large-scale OPD initiative, this correlational study (N = 1231)…

  18. Time will tell: resource continuity bolsters ecosystem services.

    Science.gov (United States)

    Schellhorn, Nancy A; Gagic, Vesna; Bommarco, Riccardo

    2015-09-01

    A common suggestion to support ecosystem services to agriculture provided by mobile organisms is to increase the amount of natural and seminatural habitat in the landscape. This might, however, be inefficient, and demands for agricultural products limit the feasibility of converting arable land into natural habitat. To develop more targeted means to promote ecosystem services, we need a solid understanding of the limitations to population growth for service-providing organisms. We propose a research agenda that identifies resource bottlenecks and interruptions over time to key beneficial organisms, emphasising their resulting population dynamics. Targeted measures that secure the continuity of resources throughout the life cycle of service-providing organisms are likely to effectively increase the stock, flow, and stability of ecosystem services.

  19. Surging electricity demand growth bolsters outlook for natural gas

    International Nuclear Information System (INIS)

    Economic expansion and regulatory reform are combining to boost global opportunities for burning gas to generate electric power. Companies producing, marketing, or transporting gas are capitalizing on the improved outlook by seizing on synergistic roles in the power generation chain. Much of the improved outlook for gas stems from projected hearty increases in global demand for electricity. Bechtel Power Corp., estimates global power generation capacity during 1994--2003 will increase to as much as 1.2 billion kw, about 25% of which could be added by independent power production (IPPs). Since about 200 bcf of gas reserves producing about 20 MMcfd of gas is needed to fuel of a 100,000 kw electric generating station for 25 years, that adds up to a major growth opportunity for gas producers. The paper discusses the assessment of gas reserves, US power growth, the intent of the Energy Policy Act of 1992 (Epact), effects of Epact, gas industry response, power marketing units, synergistic possibilities, effects on US utilities, international power imperatives, non-US projects, funding good projects, and forecasting future developments

  20. POWERDRESS and diversified expression of the MIR172 gene family bolster the floral stem cell network.

    Directory of Open Access Journals (Sweden)

    Rae Eden Yumul

    Full Text Available Termination of the stem cells in the floral meristem (also known as floral determinacy is critical for the reproductive success of plants, and the molecular activities regulating floral determinacy are precisely orchestrated during the course of floral development. In Arabidopsis thaliana, regulators of floral determinacy include several transcription factor genes, such as APETALA2 (AP2, AGAMOUS (AG, SUPERMAN (SUP, and CRABSCLAW (CRC, as well as a microRNA (miRNA, miR172, which targets AP2. How the transcription factor and miRNA genes are coordinately regulated to achieve floral determinacy is unknown. A mutation in POWERDRESS (PWR, a previously uncharacterized gene encoding a SANT-domain-containing protein, was isolated in this study as an enhancer of the weakly indeterminate ag-10 allele. PWR was found to promote the transcription of CRC, MIR172a, b, and c and/or enhance Pol II occupancy at their promoters, without affecting MIR172d or e. A mutation in mature miR172d was additionally found to enhance the determinacy defects of ag-10 in an AP2-dependent manner, providing direct evidence that miR172d is functional in repressing AP2 and thereby contributes to floral determinacy. Thus, while PWR promotes floral determinacy by enhancing the expression of three of the five MIR172 members as well as CRC, MIR172d, whose expression is PWR-independent, also functions in floral stem cell termination. Taken together, these findings demonstrate how transcriptional diversification and functional redundancy of a miRNA family along with PWR-mediated co-regulation of miRNA and transcription factor genes contribute to the robustness of the floral determinacy network.

  1. Bolstering Resilience through Teacher-Student Interaction: Lessons for School Psychologists

    Science.gov (United States)

    Liebenberg, Linda; Theron, Linda; Sanders, Jackie; Munford, Robyn; van Rensburg, Angelique; Rothmann, Sebastian; Ungar, Michael

    2016-01-01

    Schools are often the only formal service provider for young people living in socio-economically marginalized communities, uniquely positioning school staff to support positive psychosocial outcomes of youth living in adverse contexts. Using data from 2,387 school-going young people [Canada (N = 1,068), New Zealand (N = 591), and South Africa (N =…

  2. Bolstering the pipeline for primary care: a proposal from stakeholders in medical education

    OpenAIRE

    Shi, Hanyuan; Kevin C. Lee

    2016-01-01

    The Association of American Medical Colleges reports an impending shortage of over 90,000 primary care physicians by the year 2025. An aging and increasingly insured population demands a larger provider workforce. Unfortunately, the supply of US-trained medical students entering primary care residencies is also dwindling, and without a redesign in this country’s undergraduate and graduate medical education structure, there will be significant problems in the coming decades. As an institution ...

  3. Bolstering the pipeline for primary care: a proposal from stakeholders in medical education

    OpenAIRE

    Hanyuan Shi; Kevin C. Lee

    2016-01-01

    The Association of American Medical Colleges reports an impending shortage of over 90,000 primary care physicians by the year 2025. An aging and increasingly insured population demands a larger provider workforce. Unfortunately, the supply of US-trained medical students entering primary care residencies is also dwindling, and without a redesign in this country's undergraduate and graduate medical education structure, there will be significant problems in the coming decades. As an institution ...

  4. When science replaces religion: Science as a secular authority bolsters moral sensitivity

    OpenAIRE

    Onurcan Yilmaz; Hasan G Bahçekapili

    2015-01-01

    Scientific and religious thinking compete with each other on several levels. For example, activating one generally weakens the other. Since priming religion is known to increase moral behaviour and moral sensitivity, priming science might be expected to have the opposite effect. However, it was recently demonstrated that, on the contrary, science priming increases moral sensitivity as well. The present set of studies sought to replicate this effect and test two explanations for it. Study 1 us...

  5. Teaching Managers To Relate: Using Feedback To Bolster Commitment And Morale

    Directory of Open Access Journals (Sweden)

    Donald C. Smith

    2011-07-01

    Full Text Available Every text, indeed all writing in communication, either does or should stress the centrality of feedback in basic and advanced models of communication.  Most work in this area has focused on taking feedback, distilling information and using it to make good decisions.  What is lost in the traditional understanding is that feedback can be used to establish good relations.  A manager’s feedback can enhance employee/manger relationships, strengthen loyalty and commitment, and increase morale. This paper examines how managers can use feedback to make important and genuine connections with their employees; thereby getting the greatest return on human resources. A theory based “do and don’t do” framework is offered.  Establishing any good relationship is simply a matter of knowing what to say, how to say it, when and to whom.  It’s 9:00 a.m.; do you know who your employees are?

  6. 3D map of Universe bolsters case for dark energy and dark matter

    CERN Multimedia

    2003-01-01

    "Astronomers from the Sloan Digital Sky Survey (SDSS) have made the most precise measurement to date of the cosmic clustering of galaxies and dark matter, refining our understanding of the structure and evolution of the Universe" (1 page).

  7. Can developmental disorders be used to bolster claims from evolutionary psychology? a neuroconstructivist approach

    OpenAIRE

    Karmiloff-Smith, Annette; Thomas, Michael S.C.

    2004-01-01

    Book synopsis: Based on the Annual Symposium of the Jean Piaget Society, Biology and Knowledge Revisited focuses on the classic issue of the relationship between nature and nurture in cognitive and linguistic development, and their neurological substrates.

  8. Bolstering the Scientist Component in the Training of Scientist-Practitioners: One Program's Curriculum Modifications.

    Science.gov (United States)

    Larson, Lisa M.; Besett-Alesch, Tricia M.

    2000-01-01

    Presents three specific curriculum recommendations that have been implemented at one counseling psychology program to increase the didactic and experiential scientific core. Recommendations include requiring an ongoing research practicum, a qualitative methodology course, and an advanced integrative research design course specific to the…

  9. Assortative and dissortative priorities for game interaction and strategy adaptation significantly bolster network reciprocity in the prisoner’s dilemma

    International Nuclear Information System (INIS)

    In 2 × 2 prisoner’s dilemma games, network reciprocity is one mechanism for adding social viscosity, which leads to cooperative equilibrium. Here we show that combining the process for selecting a gaming partner with the process for selecting an adaptation partner significantly enhances cooperation, even though such selection processes require additional costs to collect further information concerning which neighbor should be chosen. Based on elaborate investigations of the dynamics generated by our model, we find that high levels of cooperation result from two kinds of behavior: cooperators tend to interact with cooperators to prevent being exploited by defectors and defectors tend to choose cooperators to exploit despite the possibility that some defectors convert to cooperators. (paper)

  10. Tunable ultraviolet and blue light generation from Nd:YAB random laser bolstered by second-order nonlinear processes

    Science.gov (United States)

    Moura, André L.; Carreño, Sandra J. M.; Pincheira, Pablo I. R.; Fabris, Zanine V.; Maia, Lauro J. Q.; Gomes, Anderson S. L.; de Araújo, Cid B.

    2016-06-01

    Ultraviolet and blue light were obtained by nonlinear frequency conversion in a random laser (RL) based on Nd0.10Y0.90Al3(BO3)4 nanocrystalline powder. RL operation at 1062 nm, due to the 4F3/2 → 4I11/2 transition of neodymium ions (Nd3+), was achieved by exciting the Nd3+ with a tunable beam from 680 to 920 nm covering the ground state absorption transitions to the 4F9/2, (4F7/2,4S3/2), (4F5/2,2H9/2), and 4F3/2 states. Light from 340 to 460 nm was obtained via the second-harmonic generation of the excitation beam while tunable blue light, from 417 to 486 nm, was generated by self-sum-frequency mixing between the excitation beam and the RL emission.

  11. WWW.com: A Brief Intervention to Bolster a 5th Grader's Regrouping Skills in Math

    Science.gov (United States)

    Waugh, Matthew; Harrison, Gina L.

    2014-01-01

    This study examined the efficacy of a brief math intervention using cognitive behaviour instruction (CBI) supplemented by a mnemonic cue system for a 5th grade student with math computation and fluency difficulties. Regrouping operations in addition and subtraction were the targeted skills. Curriculum-based measurements were conducted at the end…

  12. Global representation of threatened amphibians ex situ is bolstered by non-traditional institutions, but gaps remain

    DEFF Research Database (Denmark)

    Biega, A; Greenberg, D.A.; Mooers, A.O.;

    2016-01-01

    Ambitious global conservation targets have been set to manage increasing threats to amphibians. Ex situ institutions (broadly, ‘zoos’) are playing an expanding role in meeting these targets. Here, we examine the extent to which zoos house species representing the greatest overall conservation...... priority by testing how eight variables relating to extinction risk – International Union for the Conservation of Nature status, habitat specialization, obligate stream breeding, geographic range size, body size and island, high-altitude and tropical endemism – vary between amphibian species held in zoos...... and their close relatives not held in zoos. Based on 253 species found in zoos that could be confidently paired with close relatives not in zoos, and in contrast to reported patterns for birds and mammals, we find that amphibians currently held in zoos are equally as threatened as their close relatives not found...

  13. Better Patient Care At High-Quality Hospitals May Save Medicare Money And Bolster Episode-Based Payment Models.

    Science.gov (United States)

    Tsai, Thomas C; Greaves, Felix; Zheng, Jie; Orav, E John; Zinner, Michael J; Jha, Ashish K

    2016-09-01

    US policy makers are making efforts to simultaneously improve the quality of and reduce spending on health care through alternative payment models such as bundled payment. Bundled payment models are predicated on the theory that aligning financial incentives for all providers across an episode of care will lower health care spending while improving quality. Whether this is true remains unknown. Using national Medicare fee-for-service claims for the period 2011-12 and data on hospital quality, we evaluated how thirty- and ninety-day episode-based spending were related to two validated measures of surgical quality-patient satisfaction and surgical mortality. We found that patients who had major surgery at high-quality hospitals cost Medicare less than those who had surgery at low-quality institutions, for both thirty- and ninety-day periods. The difference in Medicare spending between low- and high-quality hospitals was driven primarily by postacute care, which accounted for 59.5 percent of the difference in thirty-day episode spending, and readmissions, which accounted for 19.9 percent. These findings suggest that efforts to achieve value through bundled payment should focus on improving care at low-quality hospitals and reducing unnecessary use of postacute care.

  14. A finite element lower extremity and pelvis model for predicting bone injuries due to knee bolster loading

    NARCIS (Netherlands)

    Rooij, L. van; Hoof, J. van; Barbir, A.; Made, R. van der; Slaats, P.M.A.; McCann, M.J.; Ridella, S.A.; Rupp, J.D.

    2004-01-01

    Injuries to the knee-thigh-hip (KTH) complex in frontal motor vehicle crashes are of substantial concern because of their frequency and potential to result in long-term disability. Current frontal impact Anthropometric Test Dummies (ATDs) have been shown to respond differently than human cadavers un

  15. Better Patient Care At High-Quality Hospitals May Save Medicare Money And Bolster Episode-Based Payment Models.

    Science.gov (United States)

    Tsai, Thomas C; Greaves, Felix; Zheng, Jie; Orav, E John; Zinner, Michael J; Jha, Ashish K

    2016-09-01

    US policy makers are making efforts to simultaneously improve the quality of and reduce spending on health care through alternative payment models such as bundled payment. Bundled payment models are predicated on the theory that aligning financial incentives for all providers across an episode of care will lower health care spending while improving quality. Whether this is true remains unknown. Using national Medicare fee-for-service claims for the period 2011-12 and data on hospital quality, we evaluated how thirty- and ninety-day episode-based spending were related to two validated measures of surgical quality-patient satisfaction and surgical mortality. We found that patients who had major surgery at high-quality hospitals cost Medicare less than those who had surgery at low-quality institutions, for both thirty- and ninety-day periods. The difference in Medicare spending between low- and high-quality hospitals was driven primarily by postacute care, which accounted for 59.5 percent of the difference in thirty-day episode spending, and readmissions, which accounted for 19.9 percent. These findings suggest that efforts to achieve value through bundled payment should focus on improving care at low-quality hospitals and reducing unnecessary use of postacute care. PMID:27605651

  16. Increasing the Chances of Implementing NGSS by Bolstering High School Teacher Knowledge and Views about Climate Change, a NICE NASA Example

    Science.gov (United States)

    Bleicher, R. E.

    2013-12-01

    Purpose of Presentation This paper will highlight how the results of this initial study foreshadow possibilities of NGSS (NGSS, 2013) playing out in high school classrooms in the near future. Research findings from a three-year NASA-funded project, Promoting Educational Leadership in Climate Science (PEL) will be presented. Objectives and Research Questions PEL aims to increase climate science literacy in high school teachers and students through scientific argumentation using authentic NASA data. This initial study focuses on the following questions: 1. Are teachers increasing their climate science knowledge? 2. Are there changes in teachers' views about climate change? 3. What resources and are provided to assist teachers to develop their students' scientific argumentation skills? Theoretical Framework Because of the changing nature of climate science knowledge and its relevance to societal issues, teachers must be able to understand the basic concepts and remain up-to-date on scientific issues. The need for a more thorough understanding of the concepts of climate change are highlighted by recent studies on the public perceptions and attitudes on the subject (Leiserowitz et al., 2013). Teachers need to understand the difference between skepticism as a characteristic of the nature of science and denial of climate change (Sommervillle & Hasol, 2011). Teachers need to understand the natural and human-induced factors affecting climate, and the potential consequences, and ways to mitigate and adapt to climate change. Generally, when teachers learn about a subject, they demonstrate more self-efficacy to teach about it (Bleicher & Lindgren, 2005). Analytic Strategy Data were analyzed using paired-samples t-tests, independent t -tests, and ANOVA. Latent class analysis was employed to analyze the Six America's Survey data. Correlational studies were conducted to examine possible relationships among variables. Findings in Brief Teachers' content knowledge increased significantly and teachers were more concerned about climate change after participation in PEL. Teachers with higher self-efficacy demonstrated higher climate change science knowledge. Teachers indicated that they felt more confident and were motivated to implement classroom lessons with their students that employed resources rich in NASA climate data and focused on scientific argumentation. References Bleicher, R.E., & Lindgren, J. (2005). Success in learning science and preservice science teaching self-efficacy. Journal of Science Teacher Education. 16, 205-225. Leiserowitz, A., Maibach, E., Roser-Renouf, C., Feinberg, G., & Howe, P.(2013) Climate change in the American mind: Americans' global warming beliefs and attitudes in April, 2013 Yale University and George Mason University. New Haven, CT: Yale Project on Climate Change Communication. Retrieved 7/26/13 from: http://climatechangecommunication.org/sites/default/files/reports/Climate-Beliefs-April-2013.pdf Next Generation Science Standards (NGSS). (2013). Available at http://www.nextgenscience.org/print/121. Somerville, R. C. J. & Hassol, S. J. (2011). Communicating the science of climate change. Physics Today, 64(10), 48-53.

  17. Nanotech Bolsters Semiconductor Manufacturing Gradually%纳米技术逐渐成为半导体制造业的支柱

    Institute of Scientific and Technical Information of China (English)

    Alexander E.Braun

    2006-01-01

    从表面看,纳米技术正在不断发展,但发展成效距离其发展目标-取代CMOS技术还相差甚远.由于纳米技术的主要发展方向定位于支持而不是超越当前技术,因此CMOS正在演变为纳米技术的发展平台.

  18. 77 FR 1127 - Open Meeting of the President's Council on Jobs and Competitiveness (PCJC)

    Science.gov (United States)

    2012-01-09

    .... Eastern Time. You can make an appointment to inspect statements by telephoning (202) 622-0990. All... job growth and bolster America's competitiveness around the world. The President will continue...

  19. Working with numbers and statistics a handbook for journalists

    CERN Document Server

    Livingston, Charles

    2005-01-01

    Working With Numbers and Statistics: A Handbook for Journalists will bolster math skills and improve math confidence for journalists at all skill levels. Authors Charles Livingston and Paul Voakes developed this resource book to improve journalist

  20. Oil Refining Giants to Cut Output

    Institute of Scientific and Technical Information of China (English)

    Zhang Dingmin

    2002-01-01

    @@ China's refined oil product output rose slightly in the first five months of this year on strong demand,but the two biggest domestic producers plan to cut production rates in an attempt to bolster the sluggish price.

  1. China's New Deal

    Institute of Scientific and Technical Information of China (English)

    LEO ZHANG

    2008-01-01

    @@ The RMB4-trillion stimulus package is a bold move, but the economy still needs attention China unveiled a massive spending package in November to bolster investment and consumption as exports falter amid the global economic slowdown.

  2. China Institute Proposes Weaker Yuan to Boost Growth

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ China should actively guide the yuan's exchange rate to about 6.93 against the dollar to help maintain economic growth and bolster employment, according to a report by the Ministry of Finance's research institute.

  3. Anaerobic conversion of lignocellulosic corn fiber to butyric acid, a substrate for microbial butanol production

    Science.gov (United States)

    Many factors, including sharply fluctuating fuel prices and questions regarding the sustainability of fuel produced from potential food crops, have bolstered interest in renewable fuels from alternative feedstocks. We tested pretreated and nonpretreated corn fiber for its susceptibility to hydrolys...

  4. The great escape: the role of self-esteem and self-related cognition in terror management

    OpenAIRE

    Wisman, Arnaud; Heflick, Nathan A; Goldenberg, Jamie L.

    2015-01-01

    Integrating terror management theory and objective self-awareness theory, we propose the existential escape hypothesis, which states that people with low self-esteem should be especially prone to escaping self-awareness as a distal response to thoughts of death. This is because they lack the means to bolster the self as a defense, and the propensity to bolster the self reduces the motivation to escape from self-awareness. Five studies supported this hypothesis. Individuals low,...

  5. Multibody dynamics modelling of the freight train bogie system

    Science.gov (United States)

    Ballew, B.; Chan, B. J.; Sandu, C.

    2011-04-01

    Previous work in the railway technology laboratory at Virginia Polytechnic Institute and State University (Virginia Tech) focused on better capturing the dynamics of the friction wedge, modelled using three-dimensional rigid body dynamics with unilateral contact conditions. The current study extends the previous work to a half-bogie model treated as an application of multibody dynamics with unilateral contact to model the friction wedge interactions with the bolster and the sideframe. The half-bogie model was derived using MATLAB and functions as a three dimensional, dynamic, and multibody dynamics model comprised of four rigid bodies: a bolster, two friction wedges, and a sideframe assembly. This expanded model allows each wedge four degrees of freedom: vertical displacement, longitudinal displacement (between the bolster and sideframe), pitch (rotation around the lateral axis), and yaw (rotation around the vertical axis). The bolster and the sideframe are constrained to have only the vertical degree of freedom. The geometry of these bodies can be adjusted for various simulation scenarios. The bolster can be initialised with a pre-defined yaw (rotation around the vertical axis) and the sideframe may be initialised with a pre-defined pitch/toe (rotation around the lateral axis). The results of the multibody dynamics in half-bogie model simulation are shown in comparison with results from NUCARS®, an industry standard in train-modelling software, for similar inputs.

  6. Use of negative pressure wound therapy in burn patients.

    Science.gov (United States)

    Teng, Shou-Cheng

    2016-09-01

    According to previous research, adjunctive negative pressure wound therapy (NPWT) can help manage infected wounds when applied along with appropriate debridement and antibiotic therapy as deemed clinically relevant. NPWT not only removes fluid, and reduces oedema, but also promotes perfusion around the wounds. In addition, NPWT may lead to improved graft fixation when used as a bolster, especially in patients who are less compliant or have poor graft fixation that result from using traditional methods. NPWT is a good choice to bolster skin grafts in young, active and less-compliant patients. We propose an enhanced segmental compartment-covered technique, which uses NPWT adjunctively as first-line wound treatment to help manage postoperative infection. Moreover, NPWT promotes granulation tissue formation to prepare the wound bed for subsequent skin graft and may be used as a bolster over the graft, which helps to attain skin graft viability. PMID:27547959

  7. Causes to Crack in Bolsters,Side Frames of Bogie 8A on Ice-Cooled Refrigerator Cars and Counter Measures%冰冷车转8A摇枕、侧架裂纹原因及对策

    Institute of Scientific and Technical Information of China (English)

    刘荣和

    2001-01-01

    The main conditions of bolsters and side frames of the ice-cooledrefrigerator car are described.The causes to crack are analyzed.The relevant counter measures for control of crack in bolsters and side frames on ice-cooled refrigerator cars are put forward.%介绍了冰冷车摇枕、侧架裂纹的主要情况,分析了裂纹产生的原因,提出了冰冷车摇枕、侧架裂纹控制的相关对策。

  8. Parents' Interactions with Preschoolers during Shared Book Reading: Three Strategies for Promoting Quality Interactions

    Science.gov (United States)

    Han, Jisu; Neuharth-Pritchett, Stacey

    2014-01-01

    Research shows that home environments play a critical role in developing children's early literacy skills. Given the importance of developing early literacy skills to bolster children's chances for subsequent academic success, this article highlights the role of parent-child shared book reading. Summarizing research on different types of…

  9. Biomedical Research and the Animal Rights Movement: A Contrast in Values.

    Science.gov (United States)

    Morrison, Adrian R.

    1993-01-01

    This article explains how animals are used in research in an effort to counteract animal rights literature. Reveals how medical professionals and others trained in scholarship have misquoted the scientific literature to bolster their claims against the utility of animal research. (PR)

  10. "Process and Intention": A Thirtieth-Year Reflection

    Science.gov (United States)

    Gebhardt, Richard

    2011-01-01

    "Process and Intention: A Bridge from Theory to Classroom" is rooted in a time when intuitive, experience-based awareness that we should "Teach Writing as a Process Not Product" (Murray 3) was bolstered by systematic research into the complexity of writing. Lots of years have passed since those days, so as a reminder, the author mentions five…

  11. Lessons Learned from the Collaborative Writing Process

    Science.gov (United States)

    Bhavsar, Victoria; Ahn, Ruth

    2013-01-01

    We reflect on how to implement the instrumental aspect of collaborative writing in such a way that the developmental aspect of collaborative writing is maximally fostered, based on conditions necessary for socially constructed learning. We discuss four instrumental strategies that bolster mutual ownership of the writing and protect the social…

  12. Getting Students Excited about Learning: Incorporating Digital Tools to Support the Writing Process

    Science.gov (United States)

    Saulsburry, Rachel; Kilpatrick, Jennifer Renée; Wolbers, Kimberly A.; Dostal, Hannah

    2015-01-01

    Technology--in the form of digital tools incorporated into writing instruction--can help teachers motivate and engage young children, and it may be especially critical for students who do everything they can to avoid writing. Technology may bolster student involvement, foster the engagement of reluctant or struggling writers, and support writing…

  13. School-Based Mutual Support Groups for Parents.

    Science.gov (United States)

    Simoni, Jane M.

    Parental involvement in schooling has been shown to bolster student performance. However, eliciting parents' participation in their children's schooling has proven to be an elusive task, particularly among parents from lower socio-economic and ethnic minority backgrounds. To encourage parent involvement in the school setting, an intervention that…

  14. Smartphone and mobile phone security for the clinician.

    Science.gov (United States)

    Barber, Harry

    2016-08-01

    Smartphones are near ubiquitous and widely used by doctors in discussing patients. In all communication doctors should take steps to protect confidentiality, yet there is a paucity of available information on how clinicians can bolster cyber security and minimize risk when using their mobile phone. PMID:27487057

  15. CGRP and its receptors provide new insights into migraine pathophysiology

    DEFF Research Database (Denmark)

    Ho, Tony W; Edvinsson, Lars; Goadsby, Peter J

    2010-01-01

    Over the past 300 years, the migraine field has been dominated by two main theories-the vascular theory and the central neuronal theory. The success of vasoconstrictors such as ergotamine and the triptans in treating acute migraine bolstered the vascular theory, but evidence is now emerging...

  16. Locking in on Latin America

    Institute of Scientific and Technical Information of China (English)

    MICHAEL; RICE

    2006-01-01

    China cautious as it sets up generous investment in Latin America The United States is keeping a watchful eye as China bolsters political and economic ties with Latin America. The situation has U.S. political analysts trying to determine just how China s emerging influence

  17. Of Gods and Kings

    DEFF Research Database (Denmark)

    Brisch, Nicole

    2013-01-01

    The idea that any living human being could be worshipped like a god may appear to some people unfathomable or sacrilegious. This is related to how the distinction between humans and god(s) is perceived in a given cultural context; divinity is a concept that has been understood very differently th...... to the divine to legitimize and bolster their power....

  18. Euro-Philiacs, Euro-Sceptics and Europhobics: Higher Education Policy, Values and Institutional Research

    Science.gov (United States)

    Neave, Guy

    2005-01-01

    The European higher education landscape is inhabited by three clans: the Euro-philiac, his wicked twin, the Euro-phobic and most interesting of all, the Euro-sceptic. This unholy trinity has long been with us. Though the recent Euro electoral fiasco has in all probability served to bolster the ranks of the second and third tribes.

  19. Euro-Philiacs, Euro-Sceptics and Europhobics: Higher Education Policy, Values and Institutional Research

    NARCIS (Netherlands)

    Neave, Guy

    2005-01-01

    The European higher education landscape is inhabited by three clans: the Euro-philiac, his wicked twin, the Euro-phobic and most interesting of all, the Euro-sceptic. This unholy trinity has long been with us. Though the recent Euro electoral fiasco has in all probability served to bolster the ranks

  20. How Wide Is a Squid Eye? Integrating Mathematics into Public Library Programs for the Elementary Grades

    Science.gov (United States)

    Kliman, Marlene; Jaumot-Pascual, Nuria; Martin, Valerie

    2013-01-01

    Although public library programs for the elementary grades offer explorations in a wide range of topics in which mathematics plays a role, are all too rare: Mathematics offerings are typically limited to homework help. Participating in out-of-school activities that embed mathematics in authentic ways bolsters children's skill development,…

  1. Unpacking Biases: Developing Cultural Humility in Early Childhood and Elementary Teacher Candidates

    Science.gov (United States)

    Brown, Elizabeth Levine; Vesely, Colleen K.; Dallman, Laura

    2016-01-01

    Changing demographics in the U.S. require a focus on educating future teachers on how to engage children and families with diverse backgrounds. Teacher educators have been charged to address teachers' cultural competence and provide pedagogical instruction for working with diverse populations. We bolster this line of inquiry by sharing activities…

  2. Leading Educators: Empowering Teacher-Leaders to Extend Their Reach by Leading Teams. An Opportunity Culture Case Study

    Science.gov (United States)

    Barrett, Sharon Kebschull; Han, Jiye Grace

    2013-01-01

    Leading Educators works with schools and districts to maximize the leadership development of highly effective teachers. It aims to bolster the talent pipeline by identifying and training strong potential teacher-leaders, and in turn, increasing student achievement and developing teachers on its fellows' teams. The organization's leaders believe…

  3. Justifying Educational Language Rights

    Science.gov (United States)

    May, Stephen

    2014-01-01

    The author of this chapter observes that post-9/11 there has been a rapid and significant retrenchment of multiculturalism as public policy, particularly within education. This apparent retrenchment of multiculturalism as public policy has been bolstered by parallel arguments for a more "cosmopolitan" approach to education within an…

  4. SOE Execs:Get Ready For Stock Incentives

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Stock option incentive plan will soon be available to state-owned enterprise executives, but will it lead to greater prosperity or new problems? Atrailblazing new scheme to infuse state-owned enterprises (SOEs) with incentive stock options is underway. It's a plan that may bolster company performance, but it's

  5. After Years of Scrutiny, Hundreds of Teams Still Fail to Make the NCAA's Grade

    Science.gov (United States)

    Sander, Libby

    2009-01-01

    Despite years of prodding from officials at the National Collegiate Athletic Association (NCAA) to bolster athletes' performance in the classroom, nearly 10 percent of all athletics teams in the NCAA's top division failed to meet the association's annual benchmark for academic progress, new data show. Of the 6,300 or so teams in Division I, the…

  6. Ideology, Materiality, and Counterpublicity: William E. Simon and the Rise of a Conservative Counterintelligentsia

    Science.gov (United States)

    Asen, Robert

    2009-01-01

    As a conceptual term, "counterpublic" serves scholarship best when contributing to a critical-theory project, which means that particular constellations of materiality and ideology may bolster some calls for counterpublicity while gainsaying others. This may be investigated by examining how a text upholds or betrays an advocate's values, seeking…

  7. Smartphone and mobile phone security for the clinician.

    Science.gov (United States)

    Barber, Harry

    2016-08-01

    Smartphones are near ubiquitous and widely used by doctors in discussing patients. In all communication doctors should take steps to protect confidentiality, yet there is a paucity of available information on how clinicians can bolster cyber security and minimize risk when using their mobile phone.

  8. Time to Wrap Up Doha

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Completion of the negotiations will bolster confidence in world economic growth The Doha Round of global trade talks, which kicked off in 2001,has lasted for quite some time.Despite huge differences among parties involved in the talks,it is now highly essential to complete

  9. Cosmic Ray Accelerators in the Large Magellanic Cloud

    CERN Document Server

    Butt, Yousaf M

    2010-01-01

    I point out a correlation between gamma-ray emissivity and the historical star formation rate in the Large Magellanic Cloud ~12.5 Myr ago. This correlation bolsters the view that CRs in the LMC are accelerated by conglomerations of supernova remnants: i.e. superbubbles and supergiant shells.

  10. The Problem of First-Year Seminars: Risking Disengagement through Marketplace Ideals

    Science.gov (United States)

    Hickinbottom-Brawn, Sarah; Burns, David P.

    2015-01-01

    First-year seminars (FYS) have become increasingly prevalent in North American postsecondary institutions. The popularity of such initiatives owes much to the belief that providing unprepared students general life and academic skills can bolster engagement and thereby improve retention. In this paper we argue that, despite their good intentions,…

  11. LEADERSHIP EFFECTIVENESS IN CROSS-CULTURAL BUSINESS ENVIRONMENT

    OpenAIRE

    GOSTROUSHKO VLADLENA

    2015-01-01

    Businesses are operating in an increasingly global environment, which requires careful consideration of cultural differences when marketing goods and services worldwide. Whether you are dealing with international partners or setting up an office in an overseas location, understanding typical leadership styles in that country can be extremely beneficial to bolstering smooth-running relationships.

  12. A Multidisciplinary Training Team in the Public Schools

    Science.gov (United States)

    Buktenica, Norman A.

    1970-01-01

    A multidisciplinary team approach to assessing needs and working toward prevention of school maladaptation are fostered, instead of responding to crises via a case study approach. Children are viewed in the social context of the classroom, the position of the teacheris bolstered, participation of parents is encouraged, and more cooperative use of…

  13. The Impact of Motivational Interviewing on Client Experiences of Cognitive Behavioral Therapy for Generalized Anxiety Disorder

    Science.gov (United States)

    Kertes, Angela; Westra, Henny A.; Angus, Lynne; Marcus, Madalyn

    2011-01-01

    Motivational Interviewing (MI) has recently been applied to the treatment of anxiety disorders in an effort to bolster engagement with and response rates to cognitive behavioral therapy (CBT). In a recent randomized control trial, the addition of MI as a pretreatment compared to no pretreatment was found to significantly improve response to CBT…

  14. Rhetoric and Gender in Jane Austen's "Persuasion."

    Science.gov (United States)

    Walzer, Arthur E.

    1995-01-01

    Argues for a reading of Jane Austen's "Persuasion" that undermines Joseph Duffy's reading of the novel as a commentary on shifting social class structures, and which bolsters Nancy Armstrong's reading as a commentary on female voice and the values of the domestic household. Interprets the novel in the light of 18th-century rhetorical theory. (TB)

  15. Gaming the System: Culture, Process, and Perspectives Supporting a Game and App Design Curriculum

    Science.gov (United States)

    Herro, Danielle

    2015-01-01

    Games and digital media experiences permeate the lives of youth. Researchers have argued the participatory attributes and cognitive benefits of gaming and media production for more than a decade, relying on socio-cultural theory to bolster their claims. Only recently have large-scale efforts ensued towards moving game play and design into formal…

  16. Aiming High: Exploring the Influence of Implementation Fidelity and Cognitive Demand Levels on Struggling Readers' Literacy Outcomes

    Science.gov (United States)

    Feldman, Jill; Feighan, Kelly; Kirtcheva, Elena; Heereen, Elizabeth

    2012-01-01

    Researchers studied components of a two-year school-wide Striving Readers intervention aimed at bolstering middle school teachers' use of literacy strategies to raise students' reading achievement. Although students of intervention teachers had significantly higher Iowa Test of Basic Skills (ITBS) scores than students of non-participating…

  17. 77 FR 38093 - Meeting of National Council on the Humanities

    Science.gov (United States)

    2012-06-26

    .... Jeffrey Bolster, Associate Professor at the University of New Hampshire, and Gregory White, Qualified... INFORMATION CONTACT: Lisette Voyatzis, Committee Management Officer, 1100 Pennsylvania Ave. NW., Room 529..., 1993. Dated: June 21, 2012. Lisette Voyatzis, Committee Management Officer. BILLING CODE 7536-01-P...

  18. Moving On

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Ningxia bolsters its economic strength by tapping into Arab markets and green industries For centuries,northwest China’s Ningxia Hui Autonomous Region was a prominent fulcrum on the Silk Road,an ancient trade route linking China and the Western world via the Middle East.

  19. Using the World Wide Web To Teach Francophone Culture.

    Science.gov (United States)

    Beyer, Deborah Berg; Van Ells, Paula Hartwig

    2002-01-01

    Examined use of the World Wide Web to teach Francophone culture. Suggests that bolstering reading comprehension in the foreign language and increased proficiency in navigating the Web are potential secondary benefits gained from the cultural Web-based activities proposed in the study.(Author/VWL)

  20. The Family, Flexible Work and Social Cohesion at Risk.

    Science.gov (United States)

    Carnoy, Martin

    1999-01-01

    Because of women's increased participation in the labor market, there is an increasing pressure on families. Women are expected to provide stability, focus on child development, and bolster colleagues against unemployment and retraining, whereas society is expected to provide child care facilities and flexible education. (JOW)

  1. Effective Inclusive Schools: Designing Successful Schoolwide Programs

    Science.gov (United States)

    Hehir, Thomas; Katzman, Lauren I.

    2012-01-01

    This book presents lessons learned from in-depth case studies of some of our most effective inclusive public schools. The authors conclusively demonstrate that schools can educate students with mild and severe disabilities in general education classrooms by providing special education services that link to and bolster general education…

  2. A Blended Model: Simultaneously Teaching a Quantitative Course Traditionally, Online, and Remotely

    Science.gov (United States)

    Lightner, Constance A.; Lightner-Laws, Carin A.

    2016-01-01

    As universities seek to bolster enrollment through distance education, faculty are tasked with maintaining comparable teaching/learning standards in traditional, blended, and online courses. Research has shown that there is an achievement gap between students taking courses exclusively offered online versus those enrolled in face-to-face classes.…

  3. Determinants of Resident Assistant Job Satisfaction in Privatized University Housing

    Science.gov (United States)

    Casey, Jennifer Lynn

    2009-01-01

    The general purpose of a residence life program is the improvement of the on-campus student experience in hopes of promoting personal growth, development, and education as well as bolstering retention rates and cultivating future alumni relationships. A residence life program can be found on most four year college and university campuses. Many…

  4. Reaching Patients Across the Web.

    Science.gov (United States)

    Berlin, Joey

    2015-12-01

    The explosion of social media and the expectations of frequently refreshed content have changed the rules for physicians and practices looking to market themselves and bolster their online reputation. Just as static websites have become a relatively archaic part of the online equation, the marketing expectations for physician and practice websites have changed substantially. PMID:26630237

  5. 78 FR 39346 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2013-07-01

    ... $1.40 and $5.00, resulting in potential harm to investors. To bolster the normal resilience and... Release No. 60405 (July 30, 2009), 74 FR 39362 (August 6, 2009); NOM Rules Chapter VI, Section 7(b)(3)(C... defined in the Limit Up-Limit Down Plan, for the breaking of options trades meeting the definition of...

  6. Anatomy of an Alumnus. Commentary

    Science.gov (United States)

    Weerts, David

    2011-01-01

    In today's resource scarce environment, it is no surprise that colleges and universities are seeking innovative ways to bolster charitable giving among their alumni. Stripling's article focuses on how alumni research conducted at Claremont McKenna College aims to find out what graduates need and expect from their alma mater. Claremont McKenna…

  7. Leading to High Performance: A Case Study of the Role of the Balanced Scorecard in Improving Urban Secondary Schools

    Science.gov (United States)

    Brown, Pamela C.

    2010-01-01

    The onset of the standards-based movement in education in the early 1980's, bolstered by the passing of the No Child Left Behind Act (NCLBA) of 2002, led many school districts to shift from a culture of regulatory, process-oriented compliance to one that is more results-oriented, primarily based on state-adopted summative assessment targets in…

  8. Managing CSR Globally and Locally

    DEFF Research Database (Denmark)

    L. Brown, Dana; Knudsen, Jette Steen

    Corporate Responsibility (CR) is today an essential component of corporate global strategy. CR can bolster the institutional context for market expansion (Porter and Kramer 2006); fill institutional voids (Tarun, et.al. 2005); or facilitate market entry as a component of non-market strategy (Baro...

  9. Where's the Vision? The Concept of Utopia in Contemporary Educational Theory

    Science.gov (United States)

    Webb, Darren

    2009-01-01

    This paper explores the way in which the concept of utopia is employed within contemporary educational theory. Confronted with the relentless marketisation and managerialisation of education, there is a growing willingness to embrace utopianism as a means of bolstering hope, opening up new possibilities and catalysing change. At the same time,…

  10. Looking Past the Spin: Teach for America

    Science.gov (United States)

    Miner, Barbara

    2010-01-01

    Teach for America (TFA) is perceived as a major player in the education wars over the future of public schools, and a key ally of those who disparage teacher unions and schools of education, and who are enamored of entrepreneurial reforms that bolster the privatization of a once-sacred public responsibility. But what exactly is TFA's role in these…

  11. Increasing Interest in Social Studies: Social Perspective Taking and Self-Efficacy in Stimulating Simulations

    Science.gov (United States)

    Gehlbach, Hunter; Brown, Scott W.; Ioannou, Andri; Boyer, Mark A.; Hudson, Natalie; Niv-Solomon, Anat; Maneggia, Donalyn; Janik, Laura

    2008-01-01

    This study examined the potential of simulations to bolster interest in middle school social studies classrooms. Using a pre-post-design, we examined 305 middle school students (49% female) who participated in the web-based "GlobalEd" simulation. In contrast to the motivation declines middle school students usually experience, participants in this…

  12. Vitality and Ethnolinguistic Attitudes of Acadians, Franco-Ontarians and Francophone Quebecers: Two or Three Solitudes in Canada's Bilingual Belt?

    Science.gov (United States)

    Sioufi, Rana; Bourhis, Richard Y.; Allard, Réal

    2016-01-01

    Do French-Canadian (FC) minorities in New Brunswick and Ontario remain as committed as majority Francophone Quebecers in developing their vitality within Canada's bilingual belt? FCs constitute host communities for interprovincial migrants of FC and English-Canadian (EC) background who can bolster or weaken the vitality of FCs. How FCs and ECs…

  13. 76 FR 71861 - America Recycles Day, 2011

    Science.gov (United States)

    2011-11-18

    ... recycling and management practices, the disposal of our old computers, monitors, and cell phones can release... Nation by recycling regularly and promoting conservation. During the First and Second World Wars... helped fuel our military and our economic growth. Since then, we have bolstered recycling...

  14. Enjoying the Roller Coaster Ride: Directors' Perspectives on Fostering Staff Morale in University Counseling Centers

    Science.gov (United States)

    Eells, Gregory T.; Seals, Tom; Rockett, Jeri; Hayes, Denise

    2005-01-01

    The demand for mental health services in higher education settings continues to increase and places more pressure on staff, highlighting further the importance of good staff morale in these agencies. This task of bolstering staff morale is often placed primarily on the shoulders of counseling center directors. The present article outlines several…

  15. Competition and Poverty

    OpenAIRE

    Begazo, Tania; Nyman, Sara

    2016-01-01

    A literature review shows competition policy reforms can deliver benefits for the poorest households and improve income distribution. A lack of competition in food markets hurts the poorest households the most. Competition in input markets and between buyers helps farmers and small businesses. And more competitive markets bolster job growth over the longer term. More research is needed, ho...

  16. Biodemography of human ageing

    DEFF Research Database (Denmark)

    Vaupel, James W

    2010-01-01

    Human senescence has been delayed by a decade. This finding, documented in 1994 and bolstered since, is a fundamental discovery about the biology of human ageing, and one with profound implications for individuals, society and the economy. Remarkably, the rate of deterioration with age seems to be...

  17. Campaign for Tobacco Free Kids

    Science.gov (United States)

    ... gives the FDA authority to regulate the manufacturing, marketing and sale of tobacco products National Tobacco Control Strategy Learn more about the Administration's plan to reinvigorate efforts to reduce tobacco use Health Care Reform New law bolsters disease prevention and expands coverage for ...

  18. School System (Re)design: Developing Educational Infrastructures to Support School Leadership and Teaching Practice

    Science.gov (United States)

    Hopkins, Megan; Woulfin, Sarah L.

    2015-01-01

    A central challenge for local education agencies (i.e., school districts in the United States) undergoing reform is to design systems that facilitate instructional improvement. At the core of these systems are educational infrastructures that bolster capacity building efforts and support teaching and leadership practices. Our goal for this special…

  19. Pushing the Entrepreneurial Prodigy: Canadian Aboriginal Entrepreneurship Education Initiatives

    Science.gov (United States)

    Pinto, Laura Elizabeth; Blue, Levon Ellen

    2016-01-01

    Globally, neoliberal education policy touts youth entrepreneurship education as a solution for staggering youth unemployment, a means to bolster economically depressed regions, and solution to the ill-defined changing marketplace. Many jurisdictions have emphasized a need for K-12 entrepreneurial education for the general population, and targeted…

  20. A Delve into the Deployment of eCommerce and Higher Educational Learning

    Science.gov (United States)

    Djoleto, Wilhelmina

    2012-01-01

    Higher Educational Institutions (HEIs) and organisations have made significant investments in eCommerce/eBusiness in efforts to keep up with heightened technology penetration in organisational and institutional fabrics. These efforts have been incorporated in their strategic mission partly, to bolster their reputation. HEIs reputation depends much…

  1. Assessing Conscientious Personality in Primary Care: An Opportunity for Prevention and Health Promotion

    Science.gov (United States)

    Israel, Salomon; Moffitt, Terrie E.

    2014-01-01

    The articles in this special section bolster the already strong evidence base that personality differences in the trait of conscientiousness predict health. What is now needed is a research agenda for translating documented risk associations between low conscientiousness and poor health into policies and interventions that improve health outcomes…

  2. Investigation of the influence of friction pairs geometrical parameters of wagon truck spring - frictional set on the effectiveness of their operation

    Directory of Open Access Journals (Sweden)

    Oleg CHEREPOV

    2011-01-01

    Full Text Available The article gives an account of the results of the analytical and numerical modeling of force action of friction pairs “truck bolster – frictional wedge” and “frictional wedge – frictional plank”. There have been obtained formulas for determining con-straint reactions according to friction pairs geometrical parameters which makes it possible to find their rational values.

  3. 78 FR 26701 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and...

    Science.gov (United States)

    2013-05-08

    ... strengthen liquidity risk management at Farm Credit System (System) banks, improve the quality of assets in their liquidity reserves, and bolster the ability of System banks to fund their obligations and continue... Register on April 18, 2013, (78 FR 23438) amending part 615. In FR Doc. 2013-09166, make the...

  4. 78 FR 23437 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and...

    Science.gov (United States)

    2013-04-18

    ... management from asset-liability management by stating that there is no reason why any bank would confuse the... Credit, or System) banks, improve the quality of assets in their liquidity reserves, and bolster the... at all FCS banks; Enhance the liquidity of assets that System banks hold in their liquidity...

  5. 78 FR 37101 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and...

    Science.gov (United States)

    2013-06-20

    ... liquidity risk management at Farm Credit System (System) banks, improve the quality of assets in their liquidity reserves, and bolster the ability of System banks to fund their obligation and continue operations... at Farm Credit System (System) banks, improve the quality of assets in their liquidity reserves,...

  6. 76 FR 80817 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and...

    Science.gov (United States)

    2011-12-27

    ... asset-liability functions of the bank, including interest rate management. The board's philosophy and...) banks, improve the quality of assets in the liquidity reserve, and bolster the ability of System banks... at all FCS banks; Enhance the marketability of assets that System banks hold in their...

  7. Practice Stories in Natural Resource Management Continuing Professional Education: Springboards for Learning

    Science.gov (United States)

    Stummann, Cathy Brown

    2014-01-01

    The use of stories from professional experience in continuing professional education has been on the rise in many fields, often aimed at bolstering capacity through sharing professional knowledge and/or supporting reflective practice. Practice stories are also suggested to be beneficial in supporting professional learning of new concepts. These…

  8. Apples and Oranges Mean a New Fruit Crop: New Business Plan Competition Model Integrates Economic and Community Development

    Science.gov (United States)

    Feldman, Jacqueline; Oden, Lisa Derby

    2007-01-01

    Mount Wachusett Community College Entrepreneurial Resource Center Business Plan Competition brings together stakeholders across all economic sectors to bolster the regional economy. It also highlights entrepreneurs as a viable career choice. The competition disintegrates existing silos, provides education to all entrants, and gives business…

  9. The UK’s Territorial and Governance Challenge: Regions, Nations and Cities

    OpenAIRE

    SHAW, Jo

    2015-01-01

    Faced with recent events at home and abroad, the UK’s political system needs to adapt to ensure prosperity and to bolster democratic legitimacy, writes Jo Shaw. She argues that devolution to cities might be a viable option to achieve these objectives, while also maintaining a balance in the UK’s complicated territorial politics.

  10. 7 CFR 3575.1 - General.

    Science.gov (United States)

    2010-01-01

    ... purpose of the Community Programs guaranteed loan program is to improve, develop, or finance essential community facilities in rural areas. This purpose is achieved through bolstering the existing private credit... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF...

  11. Cross-National Impacts of Public-Private Partnerships on Equitable Student Achievement: A Quasi-Experimental Assessment Using PISA 2009

    Science.gov (United States)

    Baum, Donald Rey

    2013-01-01

    Public-private partnerships are being increasingly supported and advocated for, ideologically and financially, as an approach to educational reform in many countries across the world. Proponents suggest that non-state involvement in the education sector has the potential to bolster international Education for All efforts, improve school…

  12. Data Journalism Grows Up

    OpenAIRE

    Hewett, J.

    2015-01-01

    Data journalism has evolved partly out of computer-assisted reporting (CAR) in the USA – bolstered by freedom of information (FoI), open data and journalism education. Jonathan Hewett traces the development and teaching of data journalism in the UK.

  13. 78 FR 60177 - National Public Lands Day, 2013

    Science.gov (United States)

    2013-10-01

    ... lives, and bolstering our economy. Today, as we mark the 20th anniversary of National Public Lands Day...- eighth. (Presidential Sig.) [FR Doc. 2013-24045 Filed 9-30-13; 8:45 am] Billing code 3295-F4 ... Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 9024 of September 26, 2013 National...

  14. Is Prescott right? Welfare state policies and the incentives to work, learn, and retire

    NARCIS (Netherlands)

    B. Jacobs (Bas)

    2009-01-01

    textabstractThis paper bolsters Prescott's (Fed. Reserve Bank Minneap. Q. Rev. 28(1):2-13, 2004) claim that high taxes are responsible for lackluster labor market performance in Continental European countries. We develop a life-cycle model with endogenous skill formation, endogenous labor supply, an

  15. Ecocultural Patterns of Family Engagement among Low-Income Latino Families of Preschool Children

    Science.gov (United States)

    McWayne, Christine M.; Melzi, Gigliana; Limlingan, Maria Cristina; Schick, Adina

    2016-01-01

    For the 5 million low-income Latino children in the United States who are disproportionately impacted by the numerous risk factors associated with poverty, it is essential to identify proximal protective factors that mitigate these risks and bolster the academic and social skills that are foundational to a successful transition into formal…

  16. Undergraduate Research Engagement at Major US Research Universities. Research & Occasional Paper Series: CSHE.14.13

    Science.gov (United States)

    Douglass, John Aubrey; Zhao, Chun-Mei

    2013-01-01

    Bolstered by the recommendations of the 1998 Boyer Report, US federal agencies have put significant resources into promoting opportunities for undergraduates to engage in research. American universities and colleges have been creating support programs and curricular opportunities intended to create a "culture of undergraduate research."…

  17. Soda and Tobacco Industry Corporate Social Responsibility Campaigns: How Do They Compare?

    OpenAIRE

    Lori Dorfman; Andrew Cheyne; Friedman, Lissy C; Asiya Wadud; Mark Gottlieb

    2012-01-01

    In an article that forms part of the PLoS Medicine series on Big Food, Andrew Cheyne and colleagues compare soda companies' corporate social responsibility (CSR) campaigns - which are designed to bolster the image and popularity of their products and to prevent regulation - with the tobacco industry's CSR campaigning.

  18. An Inevitable Moment: US Brain Drain

    Science.gov (United States)

    Coppola, Brian P.

    2015-01-01

    In this article, Brian Coppola begins by discussing the 2007 National Academies of Sciences (NAS) publication, "Rising Above the Gathering Storm" which called for for reprioritizing investments because "the world is changing rapidly, and our advantages are no longer unique. Without a renewed effort to bolster the foundations of our…

  19. Mood-Congruent Memory and Natural Mood: New Evidence.

    Science.gov (United States)

    Mayer, John D.; And Others

    1995-01-01

    Presents new evidence that everyday mood does bring about a hypothesized effect on memory, termed mood-congruent memory (MCM). Results of three studies provided evidence for MCM among normal individuals (n=614). Findings support prior studies and bolster notions that mood and memory constantly covary in everyday experience. (RJM)

  20. Case Study: Fuel Cells Provide Combined Heat and Power at Verizon's Garden City Central Office

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-12-01

    This case study describes how Verizon's Central Office in Garden City, NY, installed a 1.4-MW phosphoric acid fuel cell system as an alternative solution to bolster electric reliability, optimize the company's energy use, and reduce costs in an environmentally responsible manner.

  1. Partnership for the Advancement of Information Literacy in a Nursing Program

    Science.gov (United States)

    Beck, Sheila; Blake-Campbell, Barbara; McKay, Devin

    2012-01-01

    Nursing educators know that healthcare stakeholders expect nursing graduates to be able to manage information. Consequently, many nursing education programs are exploring ways of integrating information literacy across the curriculum not only to bolster evidence-based practice, but also to enhance professional development and encourage lifelong…

  2. From Shards to Stained Glass: Crowdsourcing an E-Book

    Science.gov (United States)

    Fontichiaro, Kristin

    2012-01-01

    In this article, the author discusses crowdsourcing an e-book--gathering wide, diverse opinions from the school library community (including academics, practitioners, vendors, and others), and gathering those results in a free e-book. As e-book publishers, school librarians could be active agents, bolstering community energy, creating a forum for…

  3. African American Adolescent Engagement in the Classroom and Beyond: The Roles of Mother's Racial Socialization and Democratic-Involved Parenting

    Science.gov (United States)

    Smalls, Ciara

    2009-01-01

    Previous research has explored how differential youth outcomes are associated with racial socialization and parenting style individually, but very little work has examined whether democratic-involved parenting style bolsters the positive link between racial messages and adolescent outcomes. The purpose of this study was to examine mothers' use of…

  4. The Aims, Methods, and Effects of Deliberative Civic Education through the National Issues Forums.

    Science.gov (United States)

    Gastil, John; Dillard, James P.

    1999-01-01

    Examines the goals, methods, and effects of four current deliberative civic education programs, with an in-depth analysis of one: the National Issues Forums (NIF). Shows that NIF can bolster participants' political self-efficacy, refine their political judgments, broaden their political conversation networks, and reduce their conversational…

  5. Demanding More: Legal Standards and Best Practices for English Language Learners

    Science.gov (United States)

    Haas, Eric; Gort, Mileidis

    2009-01-01

    In the current english-only programs in California, Arizona, and Massachusetts only a small percentage of students are learning English and subject matter content. This violates the success in practice prong of "Castaneda v. Pickard" (1981). Further, these program failures bolster the claim that these programs also violate castaneda's…

  6. The Role of Transnational Feminism in Psychology: Complementary Visions

    Science.gov (United States)

    Grabe, Shelly; Else-Quest, Nicole M.

    2012-01-01

    Denmark and Segovich's (2012), Hyde's (2012), and Marecek's (2012) reflections on the authors' article (Else-Quest & Grabe, 2012) further bolster the need for feminist psychology to investigate gender disparities in power. The authors offer a rejoinder that draws together the commonalities in their various perspectives by putting the study of…

  7. Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic.

    Science.gov (United States)

    Majchrzak, Kinga; Nelson, Michelle H; Bailey, Stefanie R; Bowers, Jacob S; Yu, Xue-Zhong; Rubinstein, Mark P; Himes, Richard A; Paulos, Chrystal M

    2016-03-01

    Cancer immunotherapy is one the most effective approaches for treating patients with tumors, as it bolsters the generation and persistence of memory T cells. In preclinical work, it has been reported that adoptively transferred CD4+ and CD8+ lymphocytes that secrete IL-17A (i.e., Th17 and Tc17 cells) regress tumors to a greater extent than IFN-γ(+)Th1 or Tc1 cells in vivo. Herein, we review the mechanisms underlying how infused Th17 and Tc17 cells regress established malignancies in clinically relevant mouse models of cancer. We also discuss how unique signaling cues--such as co-stimulatory molecules (ICOS and 41BB), cytokines (IL-12 and IL-23) or pharmaceutical reagents (Akt inhibitors, etc.)--can be exploited to bolster the therapeutic potential of IL-17(+) lymphocytes with an emphasis on using this knowledge to improve next-generation clinical trials for patients with cancer. PMID:26825102

  8. Revisiting Caresharing in the Context of Changes in a Florida Retirement Community

    Directory of Open Access Journals (Sweden)

    Eleanor Krassen Covan, Ph. D.

    2006-06-01

    Full Text Available In this paper I revisit the basic social process ofcaresharing whereby people engage in personal and communal strategies to maximize their pleasure and minimize their losses. I originally discovered caresharing in the context of Hollywood Falls, a Florida retirement community that provided no formal supportive services for its aging residents (Covan, 1998. There, hiding frailty was the most obvious caresharing strategy. In this community which has since become more diverse in terms of ethnicity and age, hiding frailty is no longer practical among the oldest residents. It has been surpassed by bolstering strength, a process which involves exposing need, expanding the caresharing network, stifling crises, and staking competence claims. In consequence of bolstering strength, the oldest residents are able to diminish the costs of help while augmenting opportunities for personal autonomy, thereby extending their period of residence within their ‘independent’ living community.

  9. A socioecological approach to improving mammography rates in a tribal community.

    Science.gov (United States)

    English, Kevin C; Fairbanks, Jo; Finster, Carolyn E; Rafelito, Alvin; Luna, Jolene; Kennedy, Marianna

    2008-06-01

    This article highlights the processes and intermediate outcomes of a pilot project to increase mammography rates of women in an American Indian tribe in New Mexico. Using a socioecological framework and principles of community-based participatory research, a community coalition was able to (a) bolster local infrastructure to increase access to mammography services; (b) build public health knowledge and skills among tribal health providers; (c) identify community-specific knowledge, attitudes, and beliefs related to breast cancer; (d) establish interdependent partnerships among community health programs and between the tribe and outside organizations; and (e) adopt local policy initiatives to bolster tribal cancer control. These findings demonstrate the value of targeting a combination of individual, community, and environmental factors, which affect community breast cancer screening rates and incorporating cultural strengths and resources into all facets of a tribal health promotion intervention.

  10. Source Credibility and Persuasion: The Role of Message Position in Self-Validation.

    Science.gov (United States)

    Clark, Jason K; Evans, Abigail T

    2014-05-12

    Highly credible communicators have been found to elicit greater confidence and attitudes that are based more on recipients' thoughts (i.e., self-validation) compared with non-credible sources. However, source credibility may produce different effects on thought confidence and persuasion depending on the position of an advocacy. When messages are proattitudinal, credible sources should initiate self-validation because recipients may be motivated to confirm (bolster) their existing views. Conversely, when appeals are counterattitudinal, recipients may be motivated to defend their opinions and disconfirm information. In these contexts, greater self-validation may emerge when a communicator lacks rather than possesses credibility. When a message was counterattitudinal and contained weak arguments, evidence of self-validation was found with low source credibility (Studies 1 and 2) and among participants high in defense motivation (Study 2). In response to strong, proattitudinal arguments, findings were consistent with high credibility producing self-validation when bolstering motivation was high (Study 3).

  11. The '419 Scam': An Unacceptable 'Power of the False'?

    OpenAIRE

    John Scannell

    2014-01-01

    One of the more virulent manifestations of a burgeoning virtual world is the very physical waste that underwrites its proliferation. Illegal e-waste dumping in Western Africa not only wreaks havoc on the ecosystems of its destination countries, but also bolsters the arsenal of the "419 scammers" and 'data miners,' in turn. As the pernicious nature of such online fraud is protested by Western media, and the global economic inequalities that foster such deception is conveniently ignored, the ma...

  12. Pendulum how past generations shape our present and predict our future

    CERN Document Server

    Williams, Roy H

    2012-01-01

    From New York Times bestselling author and speaker Roy H. Williams and business guru Michael R. Drew comes a revolutionary book outlining the surprising societal phenomenon that unlocks the secrets to success in the worlds of business, politics, advertising, entertainment, and more. Previously available only through private speaking engagements, the wisdom that bolstered the careers of political leaders, celebrities and business owners is now available to you in this entertaining and innovative book.

  13. Housing condition alters immunological and reproductive responses to day length in Siberian hamsters (Phodopus sungorus)

    OpenAIRE

    Weil, Zachary M.; Workman, Joanna L.; Nelson, Randy J.

    2007-01-01

    During winter, increased thermoregulatory demands coincide with limited food availability necessitating physiological trade offs among expensive physiological processes resulting in seasonal breeding among small mammals. In the laboratory, short winter-like day lengths induce regression of the reproductive tract, but also enhance many aspects of immune function. It remains unspecified the extent to which bolstered immune responses in short days represent enhanced immune function per se compar...

  14. Using Private Contracts to Create Adoptions from Foster Care

    OpenAIRE

    Mary Eschelbach Hansen

    2007-01-01

    Creating adoptions for children waiting in foster care is a good investment, but the number of adoptions created each year meets only a fraction of the need. This paper explores how the organization of the delivery of social services to waiting children and prospective adoptive families influences adoption creation. Cross-section time-series estimates are supplemented with a new augmented fixed effects procedure to demonstrate that the use of contracts with private agencies bolsters adoption ...

  15. Current practices and guidelines for clinical next-generation sequencing oncology testing

    Institute of Scientific and Technical Information of China (English)

    Samuel P. Strom

    2016-01-01

    Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadth genomic of information available to oncologists and their patients. This review will explore the ways in which this new technology is currently applied to bolster care for patients with solid tumors and hematological malignancies, focusing on practices and guidelines for assessing the technical validity and clinical utility of DNA variants identified during clinical NGS oncology testing.

  16. Returns on Business-to-Business Relationship Marketing Investments: Strategies for Leveraging Profits

    OpenAIRE

    Robert W. Palmatier; Srinath Gopalakrishna; Mark B. Houston

    2006-01-01

    Firms invest heavily in different types of business-to-business relationship marketing activities in the belief that such programs bolster their bottom line. In this study, we develop and test a conceptual model that links customer-specific relationship marketing investments to short-term, customer-specific financial outcomes. Data from a matched set of 313 business customers covered by 143 salespeople of 34 selling firms indicate that investments in social relationship marketing pay off hand...

  17. Redundancy in Public Transit - Vol. IV: Structure, Competition, and Reliability in Planning and Operations

    OpenAIRE

    Jonathan B. Bendor

    1980-01-01

    In contrast to the private sector, public services in the United States are organized monopolistically. the structure of public sector monopoly has been bolstered by the conventional wisdom in public administration, which has traditionally maintained that functional duplication is wasteful. This position has recently been challenged by a small group of political scientists and economists who suggest that a redundant organizational structure can make the execution of a given program more relia...

  18. PUBLIC-PRIVATE SECTOR RELATIONSHIPS IN DEVELOPING COUNTRIES

    OpenAIRE

    Martin J. Staab

    2003-01-01

    This paper refutes the conventional wisdom, bolstered in the wake of the Asian financial crisis that governments should not become too friendly with the private sector but, instead, should remain neutral and at arms-length distance. The empirical findings presented here indicate that countries in which governments have forged close and cooperative working relationships with the private sector have had much greater economic success. Furthermore, countries with more business-friendly public-pri...

  19. Calling the EU's bluff. Who are the real champions of biodiversity and traditional knowledge in the EU-Central American and EU-Community of Andean Nations Association Agreements?

    International Nuclear Information System (INIS)

    Global Europe and the EU's Raw Materials Initiative are designed to bolster the EU's economic position - whatever the cost - in the face of fierce global competition for both markets and resources, especially from emerging economies such as China and India. The EU also fears losing trade to the US, which has already secured trade and investment concessions from countries in the Western hemisphere, through the Dominican Republic-Central American Free Trade Agreement (DR-CAFTA) and other bilateral trade agreements.

  20. Capital Controls: Mud in the Wheels of Market Discipline

    OpenAIRE

    Kristin J. Forbes

    2004-01-01

    Widespread support for capital account liberalization in emerging markets has recently shifted to skepticism and even support for capital controls in certain circumstances. This sea-change in attitudes has been bolstered by the inconclusive macroeconomic evidence on the benefits of capital account liberalization. There are several compelling reasons why it is difficult to measure the aggregate impact of capital controls in very different countries. Instead, a new and more promising approach i...

  1. Do Smallholder, Mixed Crop-Livestock Livelihoods Encourage Sustainable Agricultural Practices? A Meta-Analysis

    OpenAIRE

    Rudel, Thomas K.; Oh-Jung Kwon; Paul, Birthe K.; Maryline Boval; Rao, Idupulapati M.; Diana Burbano; Megan McGroddy; Amy M. Lerner; Douglas White; Mario Cuchillo; Manuel Luna; Michael Peters

    2016-01-01

    As calls for bolstering ecosystem services from croplands have grown more insistent during the past two decades, the search for ways to foster these agriculture-sustaining services has become more urgent. In this context we examine by means of a meta-analysis the argument, proposed by Robert McC. Netting, that small-scale, mixed crop-livestock farming, a common livelihood among poor rural peoples, leads to environmentally sustainable agricultural practices. As predicted, mixed crop-livestock ...

  2. Coral Bleaching Susceptibility Is Decreased following Short-Term (1–3 Year) Prior Temperature Exposure and Evolutionary History

    OpenAIRE

    Haslun, Joshua A.; Strychar, Kevin B.; Gregory Buck; Sammarco, Paul W.

    2011-01-01

    Coral exposed to short periods of temperature stress (≥1.0°C above mean monthly maximum) and/or increased frequencies of high temperatures may bolster resilience to global warming associated with climate change. We compared Montastraea cavernosa (Linnaeus, 1767; Cnidaria, Scleractinia, Faviidae) from the Florida Keys National Marine Sanctuary (FKNMS) and the Flower Garden Banks National Marine Sanctuary (FGBNMS). Thermal stress has been reported frequently within the FKNMS; however, corals in...

  3. Emergent gravity: From statistical point of view

    OpenAIRE

    Majhi, Bibhas Ranjan

    2012-01-01

    Near the event horizon of a black hole, the effective theory is two dimensional conformal theory. Here we show that the holographic modes characterising this underlying conformal symmetry and the basic definition of entropy $S$ in statistical mechanics lead the equipartition law of energy. We also show that $S$ is proportional to the gravity action which suggests the emergent nature of gravity. This is further bolstered by expressing the generalised Smarr formula as a thermodynamic relation, ...

  4. The chemistry and biology of zoanthamine alkaloids and Illicium sesquiterpenes

    OpenAIRE

    Trzoss, Lynnie L.

    2012-01-01

    Natural products, or secondary metabolites, have proven significant to the existence of life. They have been used for countless reasons throughout history, including nonessential purposes such as dyes for textiles and paints. Less trivial uses, such as those related to health better demonstrate the importance of natural products. Toxic natural products had been used to bolster hunting efficiency and insect pheromones. Therapeutic natural products have long been used as dietary supplements and...

  5. Synthetic studies toward complex Schisandraceae and zoanthamine natural products

    OpenAIRE

    Fischer, Derek A.

    2008-01-01

    Natural products, or secondary metabolites of plants and animals, have proven invaluable to humanity. We have used them for myriad reasons throughout history, including non- essential purposes such as dyes for textiles and paints. Less trivial uses, such as those related to food and health better demonstrate the importance of natural products. We have made use of toxic natural products to bolster hunting efficiency (e.g. poison tipped darts), and insect pheromones and natural products with an...

  6. Defending the jurisdiction of the clinical ethicist.

    Science.gov (United States)

    Evans, John H

    2014-01-01

    In this essay I suggest that the bioethics profession's jurisdiction over healthcare ethics consultation is in need of reinforcement. I argue that as the profession becomes more successful, competitors will challenge the profession to justify its ethical claims and ask whose ethics the profession represents. This challenge will come more quickly as the profession tries to influence the ethics of healthcare organizations. I propose a method of bolstering jurisdiction that will make the profession less vulnerable to challenge in the future.

  7. Photovoltaic Barometer - EurObserv'ER - April 2013

    International Nuclear Information System (INIS)

    After the euphoria of 2011, the European Union's photovoltaic market slowed right down in 2012. EurObserv'ER puts newly-connected capacity in 2012 at 16.5 GWp compared to 22 GWp in 2011, which is a 25% slide. At global level the market generally held up, with just over 30 GWp installed, bolstered by the build-up of the America and Asian markets

  8. Pathway analysis of whole exome sequence data provides further support for the involvement of histone modification in the aetiology of schizophrenia.

    Science.gov (United States)

    Curtis, David

    2016-10-01

    Weighted burden pathway analysis was applied to whole exome sequence data for 2045 schizophrenic patients and 2045 controls. Overall, there was a statistically significant excess of pathways with more rare, functional variants in cases than in controls. Among the highest ranked were pathways relating to histone modification, as well as neuron differentiation and membrane and vesicle function. This bolsters the evidence from previous studies that histone modification pathways may be important in the aetiology of schizophrenia.

  9. The Doctrinal Method: Incorporating Interdisciplinary Methods in Reforming the Law

    OpenAIRE

    Hutchinson, Terry

    2015-01-01

    textabstractThe doctrinal methodology is in a period of change and transition. Realising that the scope of the doctrinal method is too constricting, academic lawyers are becoming eclectic in their use of research method. In this transitional time, legal scholars are increasingly infusing evidence (and meth- ods) from other disciplines into their reasoning to bolster their reform recommendations. This article considers three examples of the interplay of the discipline of law with other discipl...

  10. Motivational factors that influence the acceptance of Moodle using TAM

    OpenAIRE

    Duarte Hueros, Ana María; Arteaga Sánchez, Rocío

    2010-01-01

    Moodle and other virtual teaching platforms have bolstered the ability and motivation of universities to support distance learning. The aim of our study is to improve understanding of the motivational factors behind student satisfaction, or dissatisfaction, with the Web-based learning platform, Moodle. Our study extends the Technology Acceptance Model (TAM) to include technical support and perceived self-efficacy, with the expectation that they influence usage of Moodle. We surveyed 226 stu...

  11. Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium

    OpenAIRE

    Pyne, Michael E.; Mark R. Bruder; Murray Moo-Young; Chung, Duane A; C. Perry Chou

    2016-01-01

    Application of CRISPR-Cas9 systems has revolutionized genome editing across all domains of life. Here we report implementation of the heterologous Type II CRISPR-Cas9 system in Clostridium pasteurianum for markerless genome editing. Since 74% of species harbor CRISPR-Cas loci in Clostridium, we also explored the prospect of co-opting host-encoded CRISPR-Cas machinery for genome editing. Motivation for this work was bolstered from the observation that plasmids expressing heterologous cas9 resu...

  12. Republic of Belarus; 2009 Article IV Consultation and Second Review Under the Stand-By Arrangement-Staff Report Informational Annex; Staff Statement; Public Information Notice on the Executive Board Discussion; and Press Release

    OpenAIRE

    International Monetary Fund

    2009-01-01

    This 2009 Article IV Consultation highlights that Belarus has so far escaped a significant fall in output, despite a sharp fall in external demand. GDP declined 0.5 percent year over year in the first eight months of 2009, comparing favorably to Belarus’ main trading partners. Economic activity has been bolstered by strong domestic demand, especially for housing construction financed under government programs. Executive Directors have applauded the authorities’ commitment to a tight fisca...

  13. MARKET WATCH

    Institute of Scientific and Technical Information of China (English)

    HU YUE

    2011-01-01

    Greater Use of the Yuan In a bid to bolster the global presence of the yuan,China has expanded its yuan settlement program in cross-border trade to cover the entire nation.In July 2009,China launched the pilot program in five cities including Shanghai and Guangzhou.The mechanism was widened to cover 20 provinces,municipalities and autonomous regions across the country in June 2010.

  14. A pilot feasibility study of a peer-led mindfulness program for medical students

    OpenAIRE

    Danilewitz, Marlon; Bradwejn, Jacques; Koszycki, Diana

    2016-01-01

    Background Mindfulness meditation has gained momentum in medical circles for bolstering wellbeing and other facets of professionalism. This study evaluated the feasibility and benefits of a peer-led mindfulness meditation program (MMP) on medical student wellness and professionalism. Method Pre-clerkship students were recruited and randomized to the 8-week MMP or wait-list. Feasibility outcomes included ease of recruitment, program attendance and homework compliance. Other outcomes included s...

  15. Children, healthy eating and “threat appeals” : An investigation on their effectiveness and working processes

    OpenAIRE

    Charry, Karine

    2009-01-01

    This dissertation aimed at identifying the potential effectiveness of threat appeals in advertising communication when bolstering preadolescents’ consumptions of healthy food is considered. Obesity indeed appears as one of the main health issue for this population (8- to 12-year-olds) in our western societies. Although many prevention programs are being developed, very few appear to achieve the behavioral changes expected. Associating research on advertising persuasion among preadolescents...

  16. North Korea’s nuclear test

    OpenAIRE

    Radchenko, Sergey

    2009-01-01

    North Korea’s nuclear test serves several purposes. Its first purpose is to bolster the flagging legitimacy of the regime and, by drumming up war hysteria, achieve domestic mobilization in the face of mounting internal difficulties. Throughout North Korea’s turbulent history, the regime has periodically resorted to war hysteria, at times on even grander scale than what we have recently seen. North Korea’s Songun (army-first) policy requires periodic crises to maintain the myth of ...

  17. The Cost and Value of Early Foreign Language Instruction in America

    Institute of Scientific and Technical Information of China (English)

    张远艳

    2016-01-01

    In light of NCLB and the emphasis for the government to improve student performance, a quick, agile and competent mind, functioning with high cognitive abilities, is the aim in education. And if through Foreign Language instruction we can bolster reading abilities, the basis of all academic achievement. The aim of this essay is to analyze the cost and value of early foreign language instruction and promote, advance, and garner support and understanding about the need for early foreign language study.

  18. 鹿児島市の公立小学校における音楽教科に関する実態及び音楽と他教科との関連性についての考察(第2報)

    OpenAIRE

    新村, 元植; 川崎, 榮夫; シンムラ, ゲンショク; カワサキ, ヒデオ; Genshoku, Shimmura; Hideo, Kawasaki

    2010-01-01

    This second paper is a presentation of more extensive and detailed inquiry into relation between the musical training, learning of mathematics and Japanese language, carried among the pupils of 3rd through 6th grades of a municipal Elementary School in Kagoshima city. The results of this study have bolstered up the conclusions of our previous study. Namely, that the pupils who obtained better marks in music, had also better marks in mathematics and Japanese language.

  19. CAES Annual Report FY 2011

    Energy Technology Data Exchange (ETDEWEB)

    Kortny Rolston

    2011-10-01

    The Center for Advanced Energy Studies was created to lead research programs important to the nation, attract students and faculty to the Idaho universities and act as a catalyst for technology-based economic development. CAES is striving to meet those goals by continuing to develop its infrastructure and equipment capabilities, expand its research portfolio and bolster Idaho's energy workforce. This Annual Report details the progress CAES made in FY 2011 toward fulfilling its research, education and economic development missions.

  20. Selective Elimination of Human Regulatory T Lymphocytes In Vitro With the Recombinant Immunotoxin LMB-2

    OpenAIRE

    Attia, Peter; Daniel J Powell; Maker, Ajay V; Kreitman, Robert J.; Pastan, Ira; Rosenberg, Steven A.

    2006-01-01

    CD4+CD25+ T-regulatory cells (Treg) can inhibit the proliferation and cytokine secretion of CD4+CD25− helper T cells in mice and humans. In murine tumor models, the presence of these Treg cells can inhibit the antitumor effectiveness of T-cell transfer and active immunization approaches. We have thus initiated efforts to eliminate Treg cells selectively from human peripheral blood mononuclear cells (PBMCs) to potentially bolster antitumor responses. LMB-2 is a recombinant immunotoxin that is ...

  1. The EU policy on institutional multilingualism: between policy and practicality

    OpenAIRE

    Baaij, C.J.W.

    2012-01-01

    This article brings to light several inconsistencies within the narrative of the EU policy on institutional multilingualism. The EU has invoked fundamental EU principles of democracy, equality and transparent government, to publically bolster the need for its institutions to communicate and operate in the languages of its citizens. However, these principles do not allow for the pragmatic and budgetary arguments that the EU uses to justify the in reality limited number of official and de facto...

  2. Effects of Terrestrial Buffer Zones on Amphibians on Golf Courses

    OpenAIRE

    Puglis, Holly J.; Boone, Michelle D.

    2012-01-01

    A major cause of amphibian declines worldwide is habitat destruction or alteration. Public green spaces, such as golf courses and parks, could serve as safe havens to curb the effects of habitat loss if managed in ways to bolster local amphibian communities. We reared larval Blanchard's cricket frogs (Acris blanchardi) and green frogs (Rana clamitans) in golf course ponds with and without 1 m terrestrial buffer zones, and released marked cricket frog metamorphs at the golf course ponds they w...

  3. Republic of Tajikistan; Third Review Under the Three-Year Arrangement Under the Extended Credit Facility, Request for Waiver of Nonobservance of a Performance Criterion and Request for Modification of a Performance Criterion-Staff Report; Staff Supplements; Press Release on the Executive Board Discussion.

    OpenAIRE

    International Monetary Fund

    2010-01-01

    Economic activity is on the upswing in Tajikistan, bolstered by higher hydroelectric power production. The government is working to address the structural energy deficit and achieve energy independence, raise social expenditures, maintain a flexible exchange rate regime, and continue structural reforms. Medium-term fiscal consolidation will be essential while striking a careful balance between social and capital spending. Macroeconomic policies should shift from an anti-crisis to a post-crisi...

  4. The Single Supervisory Mechanism – Panacea or Quack Banking Regulation? : Preliminary assessments of the evolving regime for the prudential supervision of banks with the ECB involvement (August 16, 2013)

    OpenAIRE

    Tröger, Tobias

    2013-01-01

    This paper analyzes the evolving architecture for the prudential supervision of banks in the euro area. It is primarily concerned with the likely effectiveness of the SSM as a regime that intends to bolster financial stability in the steady state. By using insights from the political economy of bureaucracy it finds that the SSM is overly focused on sharp tools to discipline captured national supervisors and thus under-incentives their top-level personnel to voluntarily contribute to rigid ...

  5. The Single Supervisory Mechanism - Panacea or Quack Banking Regulation? Preliminary assessment of the evolving regime for the prudential supervision of banks with ECB involvement

    OpenAIRE

    Tröger, Tobias

    2013-01-01

    This paper analyzes the evolving architecture for the prudential supervision of banks in the euro area. It is primarily concerned with the likely effectiveness of the SSM as a regime that intends to bolster financial stability in the steady state. By using insights from the political economy of bureaucracy it finds that the SSM is overly focused on sharp tools to discipline captured national supervisors and thus underincentives their top-level personnel to voluntarily contribute to rigid supe...

  6. The Single Supervisory Mechanism - Panacea or Quack Banking Regulation? : preliminary assessment of the evolving regime for the prudential supervision of banks with ECB involvement : [Version: 16 August 2013

    OpenAIRE

    Tröger, Tobias

    2013-01-01

    This paper analyzes the evolving architecture for the prudential supervision of banks in the euro area. It is primarily concerned with the likely effectiveness of the SSM as a regime that intends to bolster financial stability in the steady state. By using insights from the political economy of bureaucracy it finds that the SSM is overly focused on sharp tools to discipline captured national supervisors and thus underincentives their top-level personnel to voluntarily contribute to rigid supe...

  7. Digital Economy Impact on Society

    OpenAIRE

    Lazãr Cristina; Epure Dãnuþ Tiberius; Spãtariu Elena Cerasela

    2011-01-01

    With this study we’re trying to bolster up the idea that digitization of information combined with the Internet is a form of general purpose technology, which rose a wide range of new possible combinations that could be provided by the digital economy. The impact of the digital economy over societies can be seen and recognized even if only part of it is measurable. The effects of digitalization the economy are seen more in the new activities and products than the productivity.

  8. China Struggles to Meet Energy Shortage

    Institute of Scientific and Technical Information of China (English)

    李端奇

    2005-01-01

    China is making plans not only to bolster1 energy production to meet everincreasing domestic needs2 but also to cut down on overall energy use in coming years. Headed by Premier Wen Jiabao, China's cabinet3 unveiled its longer-term energy development plan, in which the heart of the program is to be as energy-efficient and environmentally friendly as possible while pursuing4 economic growth between now and 2020.

  9. Time-Compressed Professionalization: The Experience of Public School Sign Language Interpreters in Mountain-Plains States

    OpenAIRE

    Bolster, Laurie A

    2005-01-01

    Laurie Bolster Abstract Rapid establishment of interpreting skill and knowledge standards for public school sign language interpreters has created a virtual mandate for their immediate, time-compressed, professionalization. A series of federal laws requiring accessibility to communication for deaf people have escalated demand for interpreters far beyond the supply. Thousands of people with varying levels of knowledge, skill, and experience, have been drawn into service in ...

  10. Can Statistics Tell Us What We Do Not Want to Hear? The Case of Complex Salary Structures

    OpenAIRE

    Gray, Mary W.

    1993-01-01

    It often appears that the most, indeed perhaps the only, effective role of statistics is to bolster decisions policymakers were prepared to take on other grounds. The secondary effects of smoking, the sex differential in SAT scores, the census undercount controvery, the validity of DNA evidence and the evidence of the relation of the race of the victim to the imposition of the death pernalty all provide examples of the intertwining of political and statistical considerations. Although the cou...

  11. Kingdom of the Netherlands; Aruba: 2007 Article IV Consultation: Staff Report; Public Information Notice on the Executive Board Discussion; and Statement by the Executive Director for the Kingdom of the Netherlands -Aruba

    OpenAIRE

    International Monetary Fund

    2008-01-01

    Aruba is one of the most developed islands in the Caribbean. Still, it is vulnerable to external shocks owing to its heavy dependence on tourism and a steady increase in public debt. Policies to support further fiscal consolidation and boost Aruba’s growth potential are needed. Maintaining macroeconomic stability will require fiscal adjustment and an appropriately tight monetary policy. Bolstering the growth potential will require creating the right conditions for private investment and div...

  12. Strategy: The Logic of War and Peace rev. and enlarged ed. by Edward N. Luttwak Cambridge, MA: The Belknap Press of Harvard University Press, 2001 / Book Review

    OpenAIRE

    Wirtz, James J.

    2003-01-01

    In the 1980s scholars in the ªelds of history and political science rediscovered the work of Carl von Clausewitz, the Prussian philosopher of war. This renewed interest sparked a brief revival of the study of war and strategy (the latter of which encompasses efforts to exploit war’s dialectic to achieve military and political victory). After relying for decades on operations research to minimize the likelihood of nuclear war by bolstering deterrence—an approach that largely eli...

  13. weSPOT: Inquiry based learning meets learning analytics

    OpenAIRE

    Specht, Marcus; Bedek, Michael; Duval, Erik; Held, Peter; Okada, Alexandra; Stefanov, Krassen; Parodi, Elisabetta; Kikis-Papadakis, K; Strahovnik

    2013-01-01

    weSPOT, a project supported by the European Commission, addresses several challenges to building personal knowledge, specifically in the area of science. It focuses on inquiry-based learning, in which the learner takes the role of a self-motivated explorer, and provides support for building these skills. The main problem areas weSPOT tackles are the general lack of inquiry skills in students from ages 12 to 25, the dearth of technological support to bolster students’ curiosity, linking ev...

  14. Current ADC Linker Chemistry

    OpenAIRE

    Jain, Nareshkumar; Smith, Sean W.; Ghone, Sanjeevani; Tomczuk, Bruce

    2015-01-01

    The list of ADCs in the clinic continues to grow, bolstered by the success of first two marketed ADCs: ADCETRIS® and Kadcyla®. Currently, there are 40 ADCs in various phases of clinical development. However, only 34 of these have published their structures. Of the 34 disclosed structures, 24 of them use a linkage to the thiol of cysteines on the monoclonal antibody. The remaining 10 candidates utilize chemistry to surface lysines of the antibody. Due to the inherent heterogeneity of conjugati...

  15. Scientists taste entrepreneurial life

    Directory of Open Access Journals (Sweden)

    Paula Gould

    2005-11-01

    Full Text Available Financing retirement from university life with the proceeds of a smart invention is undeniably an attractive prospect. Unfortunately, attempts to commercialize academic research can result all too easily in knock-backs and disappointed investors, rather than a generous pension deposit. But, if you pitch the right idea to the right market, money can be made. Not only that, the technology could do a great deal of good, while also bolstering its inventor's curriculum vitae.

  16. Economics of Homeland Security: Carcass Disposal and the Design of Animal Disease Defense

    OpenAIRE

    Jin, Yanhong H.; Haung, Wei; McCarl, Bruce A

    2005-01-01

    In an effort to bolster confidence and protect the nation the U.S. government through agencies like the Department of Homeland Security is identifying vulnerabilities and evolving strategies for protection. Agricultural food supply is one identified vulnerable area, and animal disease defense is one of the major concerns there under. Should an outbreak of animal disease occur, it is likely to have a mass slaughter and disposal of animal carcasses. The current existing policy, mainly including...

  17. Survival, Economic Mobility, and Community Among Los Angeles Fruit Vendors

    OpenAIRE

    Rosales, Rocio

    2012-01-01

    How do undocumented immigrants survive in a punitive regulatory environment? Drawing upon four years of ethnographic research, this article examines how local repressive policies affect the economic mobility of immigrant fruit vendors in Los Angeles County. In the face of government enforcement, fruit vendors have implemented strategies that allow for short-term survival but fail to bolster long-term upward mobility. The four survival strategies that I analyze include: 1) reliance on kinship ...

  18. Simplified Negative Pressure Wound Therapy in Pediatric Hand Wounds

    OpenAIRE

    Kasukurthi, Rahul; Gregory H Borschel

    2009-01-01

    Negative pressure wound therapy (NPWT) is commonly used as a bolster for skin grafts. The technique offers the benefit of negative pressure as well as reduced dressing changes. Skin grafting of the hand provides a unique challenge, and currently, the only commercially available NPWT hand dressings are adult-sized, precluding their use in small children. We present our custom NPWT “mitten” technique for use with skin grafts on the pediatric hand.

  19. Implementation Of 5S Quality Tool In Manufacturing Company A Case Study

    OpenAIRE

    Vibhor Kakkar; Vijay Singh Dalal; Vineet Choraria; Ashish S. Pareta; Anmol Bhatia

    2015-01-01

    Abstract 5S system is a technique which maintains the quality of working conditions in the organization. Amongst various available Lean resources 5S is a powerful technique that can bolster objectives of the organization to get continuous improvement in performance and productivity. This paper presents the implementation of 5S in a manufacturing company amp 5S rating system was used to audit all changes in the company which enhanced the efficiency of the workers amp ultimately the productivit...

  20. Sustainable yoga apparel

    OpenAIRE

    Jason, Helen

    2014-01-01

    The two major purposes of this study are to establish whether there is an interest in sustainably regarding locally made yoga sports equipment and to create a design concept for a product line of yoga apparel which is genuinely eco-friendly. The product line consists of a yoga mat bag, straps, pillows and a bolster. Research into issues surrounding sustainability and yoga guided the design process. In order to meet user requirements, yoga classes were observed, a survey was conducted and ...

  1. The Teacher-Student Data Link Project: Three Lasting Accomplishments

    OpenAIRE

    Cassie Pickens Jewell; Kristin Hallgren; Sarah Wissel

    2014-01-01

    In 2010, the Bill & Melinda Gates Foundation invited five states and three pilot districts in each state to participate in the Teacher-Student Data Link (TSDL) project. Mathematica developed a report presenting findings from 2011, the project’s first year of implementation. Building on that report, this brief articulates three lasting accomplishments of the TSDL project, and presents additional resources and best practices for initiatives like TSDL that intend to bolster linked teacher-stud...

  2. From Corporate Philanthropy to Creating Shared Value: Big Pharma’s New Business Models in Developing Markets

    OpenAIRE

    Smith N. Craig

    2016-01-01

    Some big companies have discovered opportunities to bolster their bottom line in emerging and developing markets by creating social value at the same time as generating economic returns. In the pharma industry some have taken the lead in using this concept of shared value to innovate and grow their business, especially in developing markets. Eli Lilly launched the NCD partnership to combat diabetes in underserved areas around the globe. The partnership improves awareness of the disease an...

  3. Medical students’ awareness and perception of national health examinations

    OpenAIRE

    Wu, Lii-Tzu; Lai, Tsuei-Yuan; Liu, Chiu-Shong; Lee, Cheng-Chun; Lin, Cheng-Chieh; Horng, Meei-Ling

    2014-01-01

    Key ingredients for upgrading health care include bolstering and appraising professional medical education. Health examination as a crucial element of health care that we must incorporate into medical education. This research evaluates medical students’ awareness of national health examinations. Two surveys, focused on health examination knowledge and perspective, were conducted for first- to fourthyear medical students, results analyzed by descriptive statistics, t-test and ANOVA. Research s...

  4. H3ABioNet computational metagenomics workshop in Mauritius: training to analyse microbial diversity for Africa

    OpenAIRE

    Baichoo, Shakuntala; Botha, Gerrit; Jaufeerally-Fakim, Yasmina; Mungloo-Dilmohamud, Zahra; Lundin, Daniel; Mulder, Nicola; Promponas, Vasilis J.; Ouzounis, Christos A.

    2015-01-01

    In the context of recent international initiatives to bolster genomics research for Africa, and more specifically to develop bioinformatics expertise and networks across the continent, a workshop on computational metagenomics was organized during the end of 2014 at the University of Mauritius. The workshop offered background on various aspects of computational biology, including databases and algorithms, sequence analysis fundamentals, metagenomics concepts and tools, practical exercises, jou...

  5. CALIMACO: desarrollo de un servicio de bibliotecario virtual para la interacción multimodal con dispositivos móviles

    OpenAIRE

    Griol, David; Patricio, Miguel Ángel; Molina, José Manuel

    2016-01-01

    In recent years smart mobile devices have bolstered new interaction scenarios that require more sophisticated human-machine interfaces. The leading developers of operating systems for these devices now provide APIs (Application Programming Interface) for developers to implement their own applications, including different solutions for developing graphical interfaces, control sensors and providing oral interaction. Despite the usefulness of these resources, defined strategies are still needed ...

  6. Tilting toward immunosuppression

    OpenAIRE

    Hotchkiss, Richard S.; Coopersmith, Craig M.; McDunn, Jonathan E.; Ferguson, Thomas A.

    2009-01-01

    The immune response goes haywire during sepsis, a deadly condition triggered by infection. Richard S. Hotchkiss and his colleagues take the focus off of the prevailing view that the key aspect of this response is an exuberant inflammatory reaction. They assess recent human studies bolstering the notion that immunosuppression is also a major contributor to the disease. Many people with sepsis succumb to cardiac dysfunction, a process examined by Peter Ward. He showcases the factors that cause ...

  7. Community Health Centers: The Untapped Resource for Public Health and Medical Preparedness

    OpenAIRE

    Wood, Kanen M.

    2008-01-01

    This article appeared in Homeland Security Affairs (January 2009), v.5 no.1 HSPD-21 was recently released to the public calling for a transformation in the national approach to public health and medical preparedness in the United States. The latest deliberations, as prioritized by this strategy, are to bolster the nation's ability to manage a public health crisis by stimulating improvements in the areas of biosurveillance, countermeasure distribution, mass casualty care, and community resi...

  8. Fasting: Molecular Mechanisms and Clinical Applications

    OpenAIRE

    Longo, Valter D.; Mattson, Mark P.

    2014-01-01

    Fasting has been practiced for millennia, but only recently studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism and bolster cellular protection. In lower eukaryotes, chronic fasting extends longevity in part by reprogramming metabolic and stress resistance pathways. In rodents intermittent or periodic fasting protects against diabetes, cancers, heart disease and neurodegeneration, while in humans it helps...

  9. Instruments assessing motivation for change in eating disorders and their psychometric properties – a review.

    OpenAIRE

    2007-01-01

    Abstract Objective: Most patients with an eating disorder are not motivated to change their behavior. Prior research has demonstrated the prognostic value of a stages of change model in predicting outcome. Further, identifying the factors which influence an individual’s decision to change may bolster treatment effectiveness. An instrument with good reliability and validity for assessing motivation in eating disorders is necessary to correctly identify the patient’s motivational state. T...

  10. The Myth of the Lone Physician: Toward a Collaborative Alternative

    OpenAIRE

    Saba, George W; Villela, Teresa J.; Chen, Ellen; Hammer, Hali; Bodenheimer, Thomas

    2012-01-01

    Cultural values and beliefs about the primary care physician bolster the myth of the lone physician: a competent professional who is esteemed by colleagues and patients for his or her willingness to sacrifice self, accept complete responsibility for care, maintain continuity and accessibility, and assume the role of lone decision maker in clinical care. Yet the reality of current primary care models is often fragmented, impersonal care for patients and isolation and burnout for many primary c...

  11. Should knowledge of classical dance be essential for medical practitioners?

    Directory of Open Access Journals (Sweden)

    Shovana T Narayan

    2014-07-01

    Full Text Available The medical field is constantly throwing challenges, leading to considerable stress for its practitioners. Medical practitioners are expected to be professional, have up-to-date knowledge and expertise, and the ability to withstand fatigue. Through it all they are expected to remain motivated, respectful and humane, patient and kind, and confident and sensitive. The author demonstrates how learning dance can stimulate creativity, increase motivation and bolster social intelligence in medical practitioners.

  12. From Slash-and-burn to Disk Ploughing: The Land Policy and Tractors Behind Erosion and Forest Pioneer Farming in Southern Xayabury Province (Laos)

    OpenAIRE

    Marc Dufumier; Jean-Richard Laffort

    2013-01-01

    Bordering Thailand, the southern part of Xayabury province is engaged in international trade and has experienced agricultural growth like nowhere else in Laos. The rapid transformation from manual slash-and-burn agriculture to mechanized, chemical-based cropping systems is often cited by Laotian authorities as a model of development. But a careful study of changes underway indicates that the reality is far less encouraging than it would appear at first. If many farmers have indeed bolstered t...

  13. How the Great Firewall of China is Blocking Tor

    OpenAIRE

    Winter, Philipp; Lindskog, Stefan

    2012-01-01

    Internet censorship in China is not just limited to the web: the Great Firewall of China prevents thousands of potential Tor users from accessing the network. In this paper, we investigate how the blocking mechanism is implemented, we conjecture how China's Tor blocking infrastructure is designed and we propose circumvention techniques. Our work bolsters the understanding of China's censorship capabilities and thus paves the way towards more effective circumvention techniques.

  14. The Influence of Concentrative Meditation Training on the Development of Attention Networks during Early Adolescence

    Directory of Open Access Journals (Sweden)

    Shruti eBaijal

    2011-07-01

    Full Text Available We investigate if concentrative meditation training (CMT offered during adolescent development benefits subsystems of attention using a quasi-experimental design. Attentional alerting, orienting, and conflict monitoring were examined using the Attention Network Test (ANT in 13, 14, and 15 yo children who received CMT as part of their school curriculum (CMT Group: N=79 vs. those who received no such training (Control Group: N=76. Alerting and conflict monitoring, but not orienting, differed between the CMT and Control Group. Only conflict monitoring demonstrated age-related improvements, with smaller conflict effect scores in older vs. younger participants. The influence of CMT on this system was similar to the influence of developmental maturity, with smaller conflict effects in the CMT vs. Control group. To examine if CMT might also bolster conflict-triggered upregulation of attentional control, conflict effects were evaluated as a function of previous trial conflict demands (high conflict vs. low conflict. Smaller current trial conflict effects were observed when previous conflict was high vs. low, suggesting that similar to adults, when previous conflict was high (vs. low children in this age-range proactively upregulated control so that subsequent trial performance was benefitted. The magnitude of conflict-triggered control upregulation was not bolstered by CMT but CMT did have an effect for current incongruent trials preceded by congruent trials. Thus, CMT’s influence on attention may be tractable and specific; it may bolster attentional alerting, conflict monitoring and reactive control, but does not appear to improve orienting.

  15. Simplified geometric model for the calculation of neutron yield in an accelerator of 18 MV for radiotherapy; Modelo geometrico simplificado para el calculo del rendimiento de neutrones en un acelerador de 18 MV para radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Paredes G, L.C.; Balcazar G, M. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico); Francois L, J.L. [FI-UNAM, 04510 Mexico D.F. (Mexico); Azorin N, J. [UAM-I, 09340 Mexico D.F. (Mexico)

    2008-07-01

    The results of the neutrons yield in different components of the bolster of an accelerator Varian Clinac 2100C of 18 MV for radiotherapy are presented, which contribute to the radiation of flight of neutrons in the patient and bolster planes. For the calculation of the neutrons yield, a simplified geometric model of spherical cell for the armor-plating of the bolster with Pb and W was used. Its were considered different materials for the Bremsstrahlung production and of neutrons produced through the photonuclear reactions and of electro disintegration, in function of the initial energy of the electron. The theoretical result of the total yield of neutrons is of 1.17x10{sup -3} n/e, considering to the choke in position of closed, in the patient plane with a distance source-surface of 100 cm; of which 15.73% corresponds to the target, 58.72% to the primary collimator, 4.53% to the levelled filter of Fe, 4.87% to the levelled filter of Ta and 16.15% to the closed choke. For an initial energy of the electrons of 18 MeV, a half energy of the neutrons of 2 MeV was obtained. The calculated values for radiation of experimental neutrons flight are inferior to the maxima limit specified in the NCRP-102 and IEC-60601-201.Ed.2.0 reports. The absorbed dose of neutrons determined through the measurements with TLD dosemeters in the isocenter to 100 cm of the target when the choke is closed one, is approximately 3 times greater that the calculated for armor-plating of W and 1.9 times greater than an armor-plating of Pb. (Author)

  16. Applying a Family-Level Economic Strengthening Intervention to Improve Education and Health-Related Outcomes of School-Going AIDS-Orphaned Children: Lessons from a Randomized Experiment in Southern Uganda.

    Science.gov (United States)

    Ssewamala, Fred M; Karimli, Leyla; Torsten, Neilands; Wang, Julia Shu-Huah; Han, Chang-Keun; Ilic, Vilma; Nabunya, Proscovia

    2016-01-01

    Children comprise the largest proportion of the population in sub-Saharan Africa. Of these, millions are orphaned. Orphanhood increases the likelihood of growing up in poverty, dropping out of school, and becoming infected with HIV. Therefore, programs aimed at securing a healthy developmental trajectory for these orphaned children are desperately needed. We conducted a two-arm cluster-randomized controlled trial to evaluate the effectiveness of a family-level economic strengthening intervention with regard to school attendance, school grades, and self-esteem in AIDS-orphaned adolescents aged 12-16 years from 10 public rural primary schools in southern Uganda. Children were randomly assigned to receive usual care (counseling, school uniforms, school lunch, notebooks, and textbooks), "bolstered" with mentorship from a near-peer (control condition, n = 167), or to receive bolstered usual care plus a family-level economic strengthening intervention in the form of a matched Child Savings Account (Suubi-Maka treatment arm, n = 179). The two groups did not differ at baseline, but 24 months later, children in the Suubi-Maka treatment arm reported significantly better educational outcomes, lower levels of hopelessness, and higher levels of self-concept compared to participants in the control condition. Our study contributes to the ongoing debate on how to address the developmental impacts of the increasing numbers of orphaned and vulnerable children and adolescents in sub-Saharan Africa, especially those affected by HIV/AIDS. Our findings indicate that innovative family-level economic strengthening programs, over and above bolstered usual care that includes psychosocial interventions for young people, may have positive developmental impacts related to education, health, and psychosocial functioning.

  17. Applying a Family-Level Economic Strengthening Intervention to Improve Education and Health-Related Outcomes of School-Going AIDS-Orphaned Children: Lessons from a Randomized Experiment in Southern Uganda.

    Science.gov (United States)

    Ssewamala, Fred M; Karimli, Leyla; Torsten, Neilands; Wang, Julia Shu-Huah; Han, Chang-Keun; Ilic, Vilma; Nabunya, Proscovia

    2016-01-01

    Children comprise the largest proportion of the population in sub-Saharan Africa. Of these, millions are orphaned. Orphanhood increases the likelihood of growing up in poverty, dropping out of school, and becoming infected with HIV. Therefore, programs aimed at securing a healthy developmental trajectory for these orphaned children are desperately needed. We conducted a two-arm cluster-randomized controlled trial to evaluate the effectiveness of a family-level economic strengthening intervention with regard to school attendance, school grades, and self-esteem in AIDS-orphaned adolescents aged 12-16 years from 10 public rural primary schools in southern Uganda. Children were randomly assigned to receive usual care (counseling, school uniforms, school lunch, notebooks, and textbooks), "bolstered" with mentorship from a near-peer (control condition, n = 167), or to receive bolstered usual care plus a family-level economic strengthening intervention in the form of a matched Child Savings Account (Suubi-Maka treatment arm, n = 179). The two groups did not differ at baseline, but 24 months later, children in the Suubi-Maka treatment arm reported significantly better educational outcomes, lower levels of hopelessness, and higher levels of self-concept compared to participants in the control condition. Our study contributes to the ongoing debate on how to address the developmental impacts of the increasing numbers of orphaned and vulnerable children and adolescents in sub-Saharan Africa, especially those affected by HIV/AIDS. Our findings indicate that innovative family-level economic strengthening programs, over and above bolstered usual care that includes psychosocial interventions for young people, may have positive developmental impacts related to education, health, and psychosocial functioning. PMID:26228480

  18. Life stress, social support, and self-esteem in an elderly population.

    Science.gov (United States)

    Krause, N

    1987-12-01

    Findings in previous studies of the stress-buffering properties of social support have been erratic. This study suggests that at least part of the reason for those inconclusive findings may be that researchers are using oversimplified models of the stress process and limited statistical approaches to assess the effects. The findings in this study indicate that social support (a) helps to reduce the deleterious effects of stress on emotional disorder primarily by bolstering the self-esteem of older adults and (b) affects psychological well-being only indirectly through self-esteem. Two distinct approaches to the statistical estimation of stress-buffering effects are also examined.

  19. Anthropogeny and Intellectual Evolution%人类起源与智能进化

    Institute of Scientific and Technical Information of China (English)

    吕宝忠

    2012-01-01

    The long evolutionary way for human can be traced back to about 5 million years ago, in which two "missing links", Ardipi-thecus ramidus and Australopithecus sediba , have been validated. There are two conflicted hypotheses, "out of Africa" and multire-gional origins. At present, the mixture of both hypotheses seems to be more valuable according to Neanderthal and Denisovan genome draft and other data. The ultimate explanation for being human is focused on the culture-making brain, especially in the cerebral hemisphere asymmetry, that bolsters the framework for 4 graded languages and 3 types of world.

  20. Placentation in mammals once grouped as insectivores

    DEFF Research Database (Denmark)

    Carter, Anthony; Enders, Allen

    2009-01-01

    Interest in insectivoran grade mammals has been reawakened by taxonomic changes that place tenrecs and golden moles in a new order and separate hedgehogs from moles, shrews and solenodons. This survey of their placentation shows there is great variation even within families. As an example three...... in a separate order (Erinaceomorpha) is bolstered by the presence of interstitial implantation, amniogenesis by cavitation, a hemochorial barrier and a prominent spongy zone; these features do not occur in shrews, moles or solenodons (Soricomorpha). Three insectivoran grade mammals deserve close attention...

  1. "We live on earth : rotating systems" : performance by J. Jarosz (PL) done at the Physics on Stage Festival

    CERN Document Server

    CERN Audiovisual Service

    2000-01-01

    Part of the Physics on Stage Festival (04-10 November 2000). During this event, the national competion winners, science teachers, science communicators, publishers, top scientists and high-level representatives of the ministries and European organisations will brainstorm future solutions to bolster physics' popularity. The programme will also include spectacular demonstrations of new educational tools; the best will be disseminated over the national TV networks and other media to the European public. A the end of the film, Dutch Performance by The Eindhoven Circus of Physics, Prof. De Waele from the Eindhoven University of Technology

  2. Instant Citrix security how-to

    CERN Document Server

    Jacob, Carmel

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Get the job done and learn as you go. A how-To book with practical recipes accompanied with rich screenshots for easy comprehension.This easy-to-follow, hands-on guide shows you how to bolster your security with real life cases and step-by-step instructions.This guide gets new users up and running with Citrix Netscaler in simple practical steps and also acts as a refresher to those with some experience of the product and its features.

  3. Visions of Mughal India: An Anthology of European Travel Writing. London, I.B. Tauris, 2007, 256 p.

    OpenAIRE

    Mitchell, Colin P.

    2013-01-01

    ed. Our understanding of Mughal India is to no small degree bolstered by a significant number of European travel accounts produced in the 16th-18th centuries. While we depend on court chronicles and religio-philosophical treatises to better understand the ‘elite’ narrative of Mughal India, the day-to-day, quotidian details of life in early modern South Asia are largely absent in such ‘indigenous’ documents. For this reason, historians of social, gender, urban and economic history are often dr...

  4. Resident physicians using modern practices for excellent documentation and care in heart failure (PUMPED CHF).

    Science.gov (United States)

    Patel, Jay; Cotorruelo-Martinez, Annia; Gill-Duncan, Nicole; Leveille, Philippe; Pearson, Julie M; Julliard, Kell; Saxena, Archana

    2014-01-01

    The most common indication for readmission among Medicare patients is congestive heart failure (CHF). Prior studies underscore the use of residents to bolster hospital-wide programs and reduce CHF readmissions. The authors assessed the effectiveness of a novel online training program designed to improve resident documentation and knowledge related to CHF. The findings suggest that despite a significant increase in knowledge scores following the online educational course, there was only a slight increase in documentation scores. Additional teaching modalities need to be identified to foster resident education and create sustained behavior change. PMID:25529788

  5. NF-kappaB in Lung Tumorigenesis

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Zhenjian [Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, 462 First Avenue, NBV 7N24, New York, NY 10016 (United States); Tchou-Wong, Kam-Meng; Rom, William N., E-mail: william.rom@nyumc.org [Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, 462 First Avenue, NBV 7N24, New York, NY 10016 (United States); Department of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, Tuxedo, NY 10987 (United States)

    2011-12-14

    The development of lung cancer in humans can be divided into three steps initiation, promotion and progression. This process is driven by alterations in related signal transduction pathways. These pathways signal the aberrant activation of NF-kappaB, a transcription factor that regulates the expression of genes important for lung tumorigenesis. Our current knowledge about the role of the NF-kappaB signaling pathway in the development of lung cancer has been bolstered by animal models demonstrating the connection between K-ras and tobacco induced lung transformation with NF-kappaB. Activation of downstream genes leads to cell proliferation, inhibition of apoptosis, angiogenesis, inflammation, invasion, and metastasis.

  6. Panic disorder: the psychobiology of external treat and introceptive distress.

    Science.gov (United States)

    Stein, Dan J

    2008-01-01

    Panic disorder seems to be mediated by the neuronal circuitry and neurochemical systems that have evolved to respond to external threatening stimuli. Distant threats activate prefrontal cortex (involved in complex planning of avoidance strategies), while immediate threats activate midbrain structures (involved in fast reflexive behaviors). Panic disorder may, however, also involve more specific interoceptive mechanisms. For example, the association between respiratory dysfunction and panic disorder has bolstered a false suffocation alarm hypothesis. Genetic and environmental contributors to panic disorder are beginning to be delineated. Effective pharmacotherapy and psychotherapy are able to normalize the relevant psychobiology.

  7. Are Your Employees Retirement-Ready?

    Science.gov (United States)

    Vorchheiner, Alan H; Zaleta, Cynthia O

    2016-01-01

    Much of the discussion on the decumulation phase of retirement savings has focused on the lack of any lifetime annuities. But there is a whole range of options sponsors can employ to facilitate the generation of retirement income and bolster financial wellness. As U.S. employers show no sign of substantially increasing spending on compensation or benefits, it is imperative that human resources professionals help employees--particularly the retiring baby boomers--to maximize what they have saved. This article presents five first-step ideas toward achieving that goal. PMID:27017793

  8. Education and Training in Radiochemistry -- The NAMP Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Patricia Paviet-Hartmann; Mansour Akbarzadeh

    2013-07-01

    A number of reports have indicated that a sizable percentage of the nation’s experts in radiochemistry are nearing retirement age. This reality has been a concern since the 1970s, when declining numbers of radiochemists worldwide was first observed. Therefore, the NAMP (National Analytical Management Program) has organized a subcommittee focused on training and education in radiochemistry. To bolster interest and increase awareness in radiochemistry, NAMP is offering webinars developed by experts on different topics relevant to radiochemistry. This paper presents our accomplishments in developing these webinars and highlights our efforts in outreaching the national and international radiochemistry community.

  9. Causal influence in neural systems: Reconciling mechanistic-reductionist and statistical perspectives. Comment on "Foundational perspectives on causality in large-scale brain networks" by M. Mannino & S.L. Bressler

    Science.gov (United States)

    Griffiths, John D.

    2015-12-01

    The modern understanding of the brain as a large, complex network of interacting elements is a natural consequence of the Neuron Doctrine [1,2] that has been bolstered in recent years by the tools and concepts of connectomics. In this abstracted, network-centric view, the essence of neural and cognitive function derives from the flows between network elements of activity and information - or, more generally, causal influence. The appropriate characterization of causality in neural systems, therefore, is a question at the very heart of systems neuroscience.

  10. Mediators of adherence among adults with comorbid diabetes and depression: The role of self-efficacy and social support.

    Science.gov (United States)

    Tovar, Elizabeth; Rayens, Mary Kay; Gokun, Yevgeniya; Clark, Michele

    2015-11-01

    Depression and diabetes have been linked in a variety of ways, and the presence of depression in those with diabetes can negatively affect adherence to care recommendations. A sample of 201 participants with Type 2 Diabetes completed a cross-sectional survey that assessed depressive symptoms, adherence, self-efficacy, social support, and personal characteristics. Multiple regression analysis was used to test whether self-efficacy and social support mediate the relationship between depressive symptoms and adherence. The findings suggest complete mediation via self-efficacy and some types of social support. Intervening to bolster self-efficacy and social support may decrease the negative effect of depression on adherence.

  11. Metathesis access to monocyclic iminocyclitol-based therapeutic agents

    Directory of Open Access Journals (Sweden)

    Albert Demonceau

    2011-05-01

    Full Text Available By focusing on recent developments on natural and non-natural azasugars (iminocyclitols, this review bolsters the case for the role of olefin metathesis reactions (RCM, CM as key transformations in the multistep syntheses of pyrrolidine-, piperidine- and azepane-based iminocyclitols, as important therapeutic agents against a range of common diseases and as tools for studying metabolic disorders. Considerable improvements brought about by introduction of one or more metathesis steps are outlined, with emphasis on the exquisite steric control and atom-economical outcome of the overall process. The comparative performance of several established metathesis catalysts is also highlighted.

  12. Fronteira, fusão, filme: um toque

    Directory of Open Access Journals (Sweden)

    Tunico Amancio

    2010-12-01

    Full Text Available Considered the first co-production between MERCOSUR countries, "The touch of the Oboe", a film by Claudio MacDowell, suffers from some sort of vagueness that shows off the difficulties of a complete commercial and cultural movie exchange between Brazil's neighbor countries. Even bolstered with powerful traditions, the productive associative project of this cinematic realization emblematizes an economical, symbolical and historical imbalance which still prevails among the countries of the Southern Common Market. The text notes some of these tensions, marked by the relationship between cinema and literature.

  13. Innovations in plant health services in Nicaragua

    DEFF Research Database (Denmark)

    Danielsen, Solveig; Centeno, Julio; López, Julio;

    2013-01-01

    Establishing a few community-based plant clinics in Nicaragua led to a series of innovations in plant health service delivery. A grassroots experiment became a nationwide initiative involving local service providers, universities, research institutions and diagnostic laboratories. This led...... to the creation of a ‘National Plant Health System’ offering regular advice to farmers. The innovations were driven by a momentum for change, committed individuals, joint learning and flexibility in programme management. External facilitation encouraged experimentation and bolstered growth of new alliances....... The development of the national plant health system was constrained by existing work cultures that limit the scope of individual and institutional innovations....

  14. Comparison of the Transport of Tetracycline-Resistant and Tetracycline-Susceptible Escherichia coli Isolated from Lake Michigan

    OpenAIRE

    Walczak, Jacob J.; Bardy, Sonia L.; Feriancikova, Lucia; Xu, Shangping

    2011-01-01

    It was recently reported that tetracycline could enhance the mobility of manure-derived Escherichia coli within saturated porous media (Walczak et al. (Water Research 45:1681–1690, 2011)). It was also shown, however, that E. coli from various sources could display marked variation in their mobility (Bolster et al. (Journal of Environmental Quality 35:1018–1025, 2009)). The focus of this research was to examine if the observed difference in the mobility of manure-derived tetracycline-resistant...

  15. Green shopping

    DEFF Research Database (Denmark)

    Thøgersen, John

    2011-01-01

    Findings suggesting that consumers buy “green” products, such as organic foods, for selfish reasons are usually accepted at face value. In this article, the author argues that the evidence backing this claim is questionable and that it reflects post hoc rationalizations and self-presentation biases......’s beliefs about intangible private benefits in a way that justifies (bolsters) one’s purchasing decision. A survey study among a representative sample of approximately 4,000 respondents from four European countries (Denmark, Germany, United Kingdom, and Italy) confirmed that this is exactly what “green...

  16. On the dynamics of the three-piece-freight truck

    DEFF Research Database (Denmark)

    Xia, Fujie; True, Hans

    2003-01-01

    and the nonlinear dry friction damping with hysteresis and stick-slip action. The bolster moves both vertically and laterally relative to the truck frames, so the friction forces on the contact surfaces of the wedges must be treated as two-dimensional vectors, and the same holds for the dry friction on the surfaces...... system that models the dynamics of the moving wagon and show the result of numerical dynamical investigations such as the calculation of the critical speed, and the dynamics of the wagon on an irregular track and compare them with test results and simulation results using NUCARS....

  17. Comptia Network+ review guide exam N10-006

    CERN Document Server

    Ferguson, Bill

    2015-01-01

    Be prepared for the Network+ exam CompTIA Network+ Review Guide is your ideal study companion for preparing for the CompTIA Network+ exam (N10-006). This concise review is the perfect companion to the CompTIA Network+ Study Guide and the CompTIA Network+ Deluxe Study Guide, with full exam coverage organized by objective for quick review and reinforcement of key topics. Each of the book's five parts is devoted to a specific domain area of the exam, providing a focused review to bolster areas of weak understanding. You get access to the Sybex test engine, which includes two bonus practice tests

  18. IDEOLOGICAL CONNOTATIONS OF THE INSCRIPTIONS OF JUMA MASJED OF ISFAHAN

    OpenAIRE

    Ghada Abdel Monem El Gemaiey

    2014-01-01

    This paper refers to the role of sacred texts in defining a building by using some texts more than others, by highlight some issues in a context while skip others, or by adopting references from the Quran or Hadith to bolster certain beliefs. The sacred texts in this mosque depend mostly on the Shiites Imams’ speech, some from Hadith of Prophet Muhammad, and the minority of the sacred texts is taken from the Quran. Minority here is not in terms of quantity but in using the context to co...

  19. Improving HCAHPS Scores with Advances in Digital Radiography.

    Science.gov (United States)

    Matthews, Marianne; Cretella, Gregg; Nicholas, William

    2016-01-01

    The imaging department can be instrumental in contributing to a healthcare facility's ability to succeed in this new era of competition. Advances in DR technology can improve patient perceptions in the imaging department by improving efficiencies and outcomes which, in turn, can ultimately bolster overall HCAHPS scores. Specific areas for improved scores by utilization of DR include nurse communication, doctor communication, pain management, and communication about medication. Value based purchasing brought with it a mandate for hospitals to track key metrics, which requires an investment in time, tools, and human resources. However, this mandate also presents hospitals and imaging departments, with an opportunity to leverage those very metrics to better market their facilities.

  20. Adapting the innovation systems approach to agricultural development in Vietnam

    DEFF Research Database (Denmark)

    Friederichsen, Rupert; Thai, Thi Minh; Neef, Andreas;

    2013-01-01

    Competing models of innovation informing agricultural extension, such as transfer of technology, participatory extension and technology development, and innovation systems have been proposed over the last decades. These approaches are often presented as antagonistic or even mutually exclusive...... into the still-dominant transfer of technology model. We show how extensionists draw selectively on these diverse discourses to foster interaction with outsiders and clients, and bolster their livelihood strategies. We conclude that the conceptual framework suggested by the innovation systems (IS) approach......’ ability to mediate between the conflicting principles of farmers’ self-organization and government control is identified as a key challenge for increasing innovative capacity in rural upland Vietnam....

  1. CERN and the Wigner Research Centre for Physics inaugurate CERN data centre’s extension in Budapest, Hungary

    CERN Multimedia

    Wigner Research Centre for Physics, Hungary

    2013-01-01

    On 13 June 2013 CERN and the Wigner Research Centre for Physics inaugurated the Hungarian data centre in Budapest, marking the completion of the facility hosting the extension for CERN computing resources. About 500 servers, 20,000 computing cores, and 5.5 Petabytes of storage are already operational at the site. The dedicated and redundant 100 Gbit/s circuits connecting the two sites are functional since February 2013 and are among the first transnational links at this distance. The capacity at Wigner will be remotely managed from CERN, substantially extending the capabilities of the Worldwide LHC Computing Grid (WLCG) Tier-0 activities and bolstering CERN’s infrastructure business continuity.

  2. Globalization Crises, Trade,and Development in Vietnam

    DEFF Research Database (Denmark)

    Abbott, Philip; Tarp, Finn

    Vietnam has been among the most successful East Asian economies, especially in weathering the external shocks of recent globalization crises—the 1997-98 Asian financial crisis and the 2008-09 great recession, financial crisis and collapse of global trade. Its success contradicts its...... that dependence and bolster the domestic economy while continuing to restructure the economy toward greater emphasis on the private sector. Growth, employment and poverty alleviation have been maintained at the expense of renewed inflation, larger budget deficits, and currency depreciation. The ‘stop-go’ nature...

  3. In Search of the jüdische Typus: A Proposed Benchmark to Test the Genetic Basis of Jewishness Challenges Notions of “Jewish Biomarkers”

    OpenAIRE

    Elhaik, E.

    2016-01-01

    The debate as to whether Jewishness is a biological trait inherent from an “authentic” “Jewish type” (jüdische Typus) ancestor or a system of beliefs has been raging for over two centuries. While the accumulated biological and anthropological evidence support the latter argument, recent genetic findings, bolstered by the direct-to-consumer genetic industry, purport to identify Jews or quantify one’s Jewishness from genomic data. To test the merit of claims that Jews and non-Jews are genetical...

  4. Countering the lingering threat of the Abu Sayyaf group

    OpenAIRE

    Cohn, Stephen C.

    2007-01-01

    This thesis will argue that the most effective strategy for eradicating the U.S. designated Foreign Terrorist Organization, the Abu Sayyaf Group (ASG), is to bolster the current peace talks between the Republic of the Philippines and the Moro Islamic Liberation Front (MILF). The MILF has been providing support and sanctuary to the ASG which has hindered U.S.-Philippine counter-terror operations. This thesis will explain why a shift in U.S.-Philippine strategy is required by examining what...

  5. An evolutionary perspective on zinc uptake by human fungal pathogens†

    Science.gov (United States)

    Wilson, Duncan

    2015-01-01

    The mammalian immune system has evolved sophisticated mechanisms to withhold essential micronutrients from invading pathogens. These processes, collectively known as nutritional immunity serve to limit microbial proliferation and bolster killing of the invader. Successful pathogens, therefore, have developed strategies to counteract nutritional immunity and acquire essential micronutrients in the restrictive environment of the infected host. Here I take advantage of the now large number of sequenced fungal genomes to explore the zinc acquisition strategies of human fungal pathogens and reflect on the evolutionary context of these uptake pathways. PMID:25652414

  6. Capable of Suicide: A Functional Model of the Acquired Capability Component of the Interpersonal-Psychological Theory of Suicide

    Science.gov (United States)

    Smith, Phillip N.; Cukrowicz, Kelly C.

    2016-01-01

    The current review aims to present a functional model of the acquired capability for suicide; a component of Joiner’s (2005) Interpersonal-Psychological Theory of Suicide. This review is aimed at integrating the points discussed by Joiner into a unified and specific conceptualization of acquired capability. Additionally, we offer some points of elaboration; such as the interaction between specific diatheses with life events, the role of short-term bolstering of the capability for suicide, and how contextual factors moderate the experience of painful and provocative life events; thereby leading to fearlessness and pain insensitivity to the actions and ideas involved in suicide. PMID:20560748

  7. Implementation Of 5S Quality Tool In Manufacturing Company A Case Study

    Directory of Open Access Journals (Sweden)

    Vibhor Kakkar

    2015-02-01

    Full Text Available Abstract 5S system is a technique which maintains the quality of working conditions in the organization. Amongst various available Lean resources 5S is a powerful technique that can bolster objectives of the organization to get continuous improvement in performance and productivity. This paper presents the implementation of 5S in a manufacturing company amp 5S rating system was used to audit all changes in the company which enhanced the efficiency of the workers amp ultimately the productivity of the company is enhanced to 91 .

  8. Immunity challenge.

    Science.gov (United States)

    Davenport, R John

    2003-06-11

    As people get older, their immune systems falter. The elderly are more susceptible to infections than youngsters are, and hyperactive inflammatory responses appear to contribute to some age-associated illnesses, including Alzheimer's disease and atherosclerosis. Investigating the effect of aging on the immune system was once a scientific stepchild, but card-carrying immunologists are now tackling the problem head-on. Despite the immune system's complexity, researchers have started to make sense of how its components change with age. As the research progresses, scientists hope to bolster elderly people's response to infectious diseases and quiet the inflammation that can make aging a painful experience. PMID:12844525

  9. Architectural quality: innovation, technological research and design

    Directory of Open Access Journals (Sweden)

    Andrea Campioli

    2011-04-01

    Full Text Available Architectural redevelopment and the revival of the construction sector are conditional on the incentivisation and bolstering of innovation processes. Thus the partial declensions that have been attached to these processes over the last few years have seen research and experimentation being tailored to the spectacularisation of shapes or the hidden performance optimisation of materials and components. Genuine improvement in the quality of architecture and its construction in this day and age depends on the abilities of designers to adopt the entire life cycle of buildings as a reference framework and on the willingness of all those working in the construction supply chain to activate virtuous cooperation.

  10. Contributed Review: Quartz force sensing probes for micro-applications

    Science.gov (United States)

    Abrahamians, Jean-Ochin; Pham Van, Laurent; Régnier, Stéphane

    2016-07-01

    As self-sensing and self-exciting probes, quartz sensors present many advantages over silicon cantilevers for microscopy, micro-robotics, and other micro-applications. Their development and use is further bolstered by the fact that they can be manufactured from common quartz components. This paper therefore reviews applications of the increasingly popular quartz tuning fork probes as force sensors in the literature and examines the options for higher-frequency quartz probes using the other available types of flexional, thickness-shear or length-extensional resonators.

  11. ISES International Solar Energy Society: Italian Section report. Rapporto del Comitato Energia Eolica della Sezione Italiana dell'ISES: Comitati di lavoro ISES

    Energy Technology Data Exchange (ETDEWEB)

    Sesto, E.; Stancampiano, M.

    After a brief introduction highlighting the potential benefits to be derived from the suitable application of wind turbines, in terms of economic and environmentally compatible energy supplies for remote areas, this paper gives a panoramic look at wind turbine commercialization activities in Italy. The main manufacturers and technical characteristics of the three most promising wind turbines are reported. Comments are made on world market trends and incentive programs being developed by the Italian Government and the European Communities to help bolster industrial participation in this sector.

  12. Practice stories in natural resource management continuing professional education: springboards for learning

    DEFF Research Database (Denmark)

    Stummann, Cathy Brown

    2014-01-01

    in supporting professional learning of new concepts. These uses of practice stories are not evident in public natural resource management (NRM) continuing professional education. In light of greater public involvement in NRM practice over the last 20 years, however, the use of practice stories could now......The use of stories from professional experience in continuing professional education has been on the rise in many fields, often aimed at bolstering capacity through sharing professional knowledge and/or supporting reflective practice. Practice stories are also suggested to be beneficial...

  13. Managing Corporate Responsibility Globally and Locally

    DEFF Research Database (Denmark)

    Brown, Dana; Knudsen, Jette Steen

    2012-01-01

    to be highly sensitive to local contexts. How can transnational firms organize CR so as to maximize efficiencies from globalization and to minimize the fragmentation of corporate organizational cultures? provide a framework for analyzing the way that corporations coordinate global and local functions. We build......Corporate Responsibility (CR) is today an essential component of corporate global strategy. CR can bolster the institutional context for market expansion fill institutional voids or facilitate market entry as a component of non-market strategy. Yet, in fulfilling these functions, CR may need...

  14. Lessons Learned Concerning the Human Element in Events and Training

    Energy Technology Data Exchange (ETDEWEB)

    Michael D. Sandvig

    2006-02-01

    As the number and complexity of responses to hazardous material incidents have increased, government regulators have implemented a national incident command system, bolstered by a host of protective measures and response equipment. Special advanced technical equipment has also been developed and made available to on-scene responders and command staff. Yet with all the investment in organizational and technical advance, the human element of emergency response remains critical and also needs our continued attention to ensure effective operation and success. This paper focuses on lessons learned from radiological events and training exercises that pertain to these human elements.

  15. Joomla! 25 Beginner's Guide

    CERN Document Server

    Tiggeler, Eric

    2012-01-01

    Written with a fast-paced but friendly and engaging approach, this Packt Beginner's guide is designed to be placed alongside the computer as your guide and mentor. Step-by-step tutorials are bolstered by explanations of the reasoning behind what you are doing. You will quickly pick up the necessary skills, tips, and tricks for building a successful Joomla! website. This book is written for beginners to website design. By the end of the book you will have built a complete custom content managed website, and be ready to build any kind of website.

  16. Insights into the Ukrainian Crisis

    Directory of Open Access Journals (Sweden)

    Costel Daniel Arfire

    2014-05-01

    Full Text Available Political crises are increasingly frequent and devastating not only for the population of a state, but also for the international diplomacy. Such an example is the ongoing Ukrainian crisis. Starting from S. Fink‘s life cycle of a crisis and T.W. Coombs‘s crisis response strategies, I will analyse the evolution of the Ukrainian crisis and the crisis response strategies of three major international actors: Vladimir Putin, Barack Obama and Angela Merkel. The findings of my study will prove that the denial strategy prevails in Putin‘s statement, whereas Obama uses the diminish strategy and Merkel focuses on the bolstering strategy.

  17. Financial Planning and Financial Instruments: 2013 in Review, 2014 in Prospect

    Directory of Open Access Journals (Sweden)

    Mark Brimble

    2013-09-01

    Full Text Available The Global Financial Crisis (GFC; changes in regulation; issues in public perception and trust have contributed to a troubled 2013 for financial planners. As financial planning and wealth management providers seek to bolster their professional status, the Financial Planning Education Council’s National Curriculum and Accreditation Framework and ASIC’s minimum training requirements are also a space to watch. In prospect, 2014 will offer opportunities and challenges in the form of a changed government; regulatory changes; accreditation challenges and the hope of the recruitment of strong financial planning and wealth management professionals for the future.

  18. Asteroseismology of the Solar Analogs 16 Cyg A and B from Kepler Observations

    DEFF Research Database (Denmark)

    Metcalfe, T. S.; Chaplin, W. J.; Appourchaux, T.;

    2012-01-01

    The evolved solar-type stars 16 Cyg A and B have long been studied as solar analogs, yielding a glimpse into the future of our own Sun. The orbital period of the binary system is too long to provide meaningful dynamical constraints on the stellar properties, but asteroseismology can help because ...... system, bolstering our confidence in the reliability of asteroseismic techniques. The longer data sets that will ultimately become available will allow future studies of differential rotation, convection zone depths, and long-term changes due to stellar activity cycles....

  19. Multidisciplinary design optimization of vehicle instrument panel based on multi-objective genetic algorithm

    Science.gov (United States)

    Wang, Ping; Wu, Guangqiang

    2013-03-01

    Typical multidisciplinary design optimization(MDO) has gradually been proposed to balance performances of lightweight, noise, vibration and harshness(NVH) and safety for instrument panel(IP) structure in the automotive development. Nevertheless, plastic constitutive relation of Polypropylene(PP) under different strain rates, has not been taken into consideration in current reliability-based and collaborative IP MDO design. In this paper, based on tensile test under different strain rates, the constitutive relation of Polypropylene material is studied. Impact simulation tests for head and knee bolster are carried out to meet the regulation of FMVSS 201 and FMVSS 208, respectively. NVH analysis is performed to obtain mainly the natural frequencies and corresponding mode shapes, while the crashworthiness analysis is employed to examine the crash behavior of IP structure. With the consideration of lightweight, NVH, head and knee bolster impact performance, design of experiment(DOE), response surface model(RSM), and collaborative optimization(CO) are applied to realize the determined and reliability-based optimizations, respectively. Furthermore, based on multi-objective genetic algorithm(MOGA), the optimal Pareto sets are completed to solve the multi-objective optimization(MOO) problem. The proposed research ensures the smoothness of Pareto set, enhances the ability of engineers to make a comprehensive decision about multi-objectives and choose the optimal design, and improves the quality and efficiency of MDO.

  20. Towards high performing hospital enterprise systems: an empirical and literature based design framework

    Science.gov (United States)

    dos Santos Fradinho, Jorge Miguel

    2014-05-01

    Our understanding of enterprise systems (ES) is gradually evolving towards a sense of design which leverages multidisciplinary bodies of knowledge that may bolster hybrid research designs and together further the characterisation of ES operation and performance. This article aims to contribute towards ES design theory with its hospital enterprise systems design (HESD) framework, which reflects a rich multidisciplinary literature and two in-depth hospital empirical cases from the US and UK. In doing so it leverages systems thinking principles and traditionally disparate bodies of knowledge to bolster the theoretical evolution and foundation of ES. A total of seven core ES design elements are identified and characterised with 24 main categories and 53 subcategories. In addition, it builds on recent work which suggests that hospital enterprises are comprised of multiple internal ES configurations which may generate different levels of performance. Multiple sources of evidence were collected including electronic medical records, 54 recorded interviews, observation, and internal documents. Both in-depth cases compare and contrast higher and lower performing ES configurations. Following literal replication across in-depth cases, this article concludes that hospital performance can be improved through an enriched understanding of hospital ES design.

  1. Activism as a Heroic Quest for Symbolic Immortality: An Existential Perspective on Collective Action

    Directory of Open Access Journals (Sweden)

    Julia Elad-Strenger

    2016-03-01

    Full Text Available Excellent research exists on the conditions that generate political and social activism. Yet a central issue has remained perplexing: how does the personal need to stand out as unique and heroic interact with the concern for the positive image of the group, and the desire to protect and bolster its status, goals and shared values, in propelling collective action? Inspired by existential theory and research, this paper proposes an existential perspective on activism that identifies the human desire for a sense of meaning and significance as an important motivation underlying individuals' choice to engage in collective action. This study outlines an integrative model of collective action, combining insights from existential psychology with insights from the social identity perspective, to bridge together needs and concerns associated with both personal identity and group identity into a single model of collective action through the concept of death-anxiety buffering mechanisms. This model suggests that collective action is an effective means to satisfy existential needs through bolstering and protecting group interests and values on the one hand, and realizing the activist's heroism project on the other. Suggestions for future research are discussed.

  2. 大功率交流电力机车枕梁簧座焊接工艺优化%Welding Technics Improving to the Spring Pedestal of High - power AC Electric Locomotive

    Institute of Scientific and Technical Information of China (English)

    贺煣; 许立勇; 谷祥帅

    2013-01-01

    This paper presents the product structure ,welding quality requirement ,assembling and welding scheme of the spring pedestal which used in the bolster beam of High - power AC Transmission Electric Locomotive .According to the analysis of the welding fault which caused by manual welding method and robot -welding method ,improved the welding technics and established an effective solution ,finally ensures the welding quality and heightens the manufacture efficiency of the spring pedestal which used in the bolster beam .%  文章介绍了大功率交流传动电力机车枕梁簧座产品结构、焊接质量要求、装配和焊接方案,对焊接缺陷进行了系统分析,制定了有效的解决措施,保证了枕梁簧座的焊接质量,提高了生产效率。

  3. Enhancing youth health in primary care: lessons learned from general practitioners.

    Science.gov (United States)

    Dadich, Ann; Jarrett, Carmen; Robards, Fiona; Bennett, David

    2014-01-01

    Primary care represents a fundamental component of the health system, particularly for young people. However, youth access to primary care is less than ideal. To optimize clinician capacity to promote youth health, an interactive training module was developed and tailored to the needs of general practitioners. As part of an exploratory study, 11 participants were interviewed to determine the perceived capacity of the module to promote youth-friendly primary care. Findings suggest the module can enhance clinician skills, knowledge, and confidence to promote youth health; however, it has a limited ability to inform how organizational capacity might be bolstered-this includes the development of interagency networks. In this epoch of primary care reform, these findings are important for two key reasons. First, they reveal the need to bolster clinicians' perceived ability to use youth healthcare skills; second, they highlight the complementary importance of organizational support to ensure and sustain youth-friendly practices. The article concludes with a discussion of key implications for policymakers, practitioners, and researchers.

  4. mRNA Transfection to Improve NK Cell Homing to Tumors.

    Science.gov (United States)

    Levy, Emily R; Carlsten, Mattias; Childs, Richard W

    2016-01-01

    The ability of natural killer (NK) cells to mediate antitumor effects following adoptive transfer is dependent on their capacity to traffic to the microenvironment where tumors reside. Recent studies have shown that cytokine-activated and ex vivo-expanded NK cells lack or express at low levels homing receptors required to achieve tissue-specific tumor targeting by cells administered intravenously. In this chapter, we describe a method to enhance NK cell homing toward specific chemoattractants expressed in secondary lymphoid tissues through genetic modification of NK cells using mRNA electroporation. The method described here is scalable, cGMP-compliant, and offers a strategy to bolster the efficacy of adoptive NK cell immunotherapy for the treatment of hematological malignancies in the clinic. PMID:27177670

  5. Perceived control qualifies the effects of threat on prejudice.

    Science.gov (United States)

    Greenaway, Katharine H; Louis, Winnifred R; Hornsey, Matthew J; Jones, Janelle M

    2014-09-01

    People sometimes show a tendency to lash out in a prejudiced manner when they feel threatened. This research shows that the relationship between threat and prejudice is moderated by people's levels of perceived control: Threat leads to prejudice only when people feel concurrently low in control. In two studies, terrorist threat was associated with heightened prejudice among people who were low in perceived control over the threat (Study 1; N = 87) or over their lives in general (Study 2; N = 2,394), but was not associated with prejudice among people who were high in perceived control. Study 3 (N = 139) replicated this finding experimentally in the context of the Global Financial Crisis. The research identifies control as an important ingredient in threatening contexts that, if bolstered, can reduce general tendencies to lash out under threat.

  6. CSLAA and FAA'S Rules: Incorporating a 'Risk Management Framework' to Minimise Human Space Flight Risks

    Science.gov (United States)

    Chaddha, S.

    2012-01-01

    th This year marks the 50 anniversary of a landmark victory for humankind in its endeavour of entering and exploring the final frontier. During these years of space activity, we have witnessed a number of cumulative successes. One of which is the emergence of the commercial human space flight, or "space tourism", market. Commercial companies have the aim of travelling people into space safely and affordably. This paper shall consider the U.S. regulatory framework governing the space tourism market. It scrutinises the adequacy of the Commercial Space Launch and Amendment Act of 2004 (CSLAA), as bolstered by the FAA's requirements, to protect launching passengers to an acceptable standard of safety from the inherent risks associated with human space flights. It is argued that the legislative regime embeds a three-limb "risk management framework" as an appropriate response to address the concern over the safety of public space travel.

  7. The people's role in U.S. national health security: past, present, and future.

    Science.gov (United States)

    Schoch-Spana, Monica

    2012-03-01

    Over the past decade, assumptions have been made and unmade about what officials can expect of average people confronting a bioterrorist attack or other major health incident. The reframing of the public in national discourse and doctrine from a panic-stricken mob to a band of hearty survivors is a positive development and more realistic in terms of the empirical record. So, too, is the realization that citizen contributions to national health security encompass not only individual preparedness and volunteerism but also mutual aid and collective deliberation of the tough choices posed by health disasters. In projecting what needs to occur over the next 10 years in biosecurity, 2 priority challenges emerge: retaining the lesson that a public prone to panic, social disorder, and civil unrest is a myth, and building an infrastructure to bolster the public's full contributions to health emergency management.

  8. Linking population, fertility, and family planning with adaptation to climate change: perspectives from Ethiopia.

    Science.gov (United States)

    Rovin, Kimberly; Hardee, Karen; Kidanu, Aklilu

    2013-09-01

    Global climate change is felt disproportionately in the world's most economically disadvantaged countries. As adaption to an evolving climate becomes increasingly salient on national and global scales, it is important to assess how people at the local-level are already coping with changes. Understanding local responses to climate change is essential for helping countries to construct strategies to bolster resilience to current and future effects. This qualitative research investigated responses to climate change in Ethiopia; specifically, how communities react to and cope with climate variation, which groups are most vulnerable, and the role of family planning in increasing resilience. Participants were highly aware of changing climate effects, impacts of rapid population growth, and the need for increased access to voluntary family planning. Identification of family planning as an important adaptation strategy supports the inclusion of rights-based voluntary family planning and reproductive health into local and national climate change adaptation plans.

  9. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Tavacoli, Gh

    2011-01-01

    Full Text Available Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist, then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences; the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  10. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Gholamhosein Tavacoly

    2011-09-01

    Full Text Available   Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist , then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.   In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  11. Halogen Bonding Promotes Higher Dye-Sensitized Solar Cell Photovoltages.

    Science.gov (United States)

    Simon, Sarah J C; Parlane, Fraser G L; Swords, Wesley B; Kellett, Cameron W; Du, Chuan; Lam, Brian; Dean, Rebecca K; Hu, Ke; Meyer, Gerald J; Berlinguette, Curtis P

    2016-08-24

    We report here an enhancement in photovoltage for dye-sensitized solar cells (DSSCs) where halogen-bonding interactions exist between a nucleophilic electrolyte species (I(-)) and a photo-oxidized dye immobilized on a TiO2 surface. The triarylamine-based dyes under investigation showed larger rate constants for dye regeneration (kreg) by the nucleophilic electrolyte species when heavier halogen substituents were positioned on the dye. The open-circuit voltages (VOC) tracked these kreg values. This analysis of a homologous series of dyes that differ only in the identity of two halogen substituents provides compelling evidence that the DSSC photovoltage is sensitive to kreg. This study also provides the first direct evidence that halogen-bonding interactions between the dye and the electrolyte can bolster DSSC performance.

  12. Considering an affect regulation framework for examining the association between body dissatisfaction and positive body image in Black older adolescent females: does body mass index matter?

    Science.gov (United States)

    Webb, Jennifer B; Butler-Ajibade, Phoebe; Robinson, Seronda A

    2014-09-01

    The present study provided an initial evaluation of an affect regulation model describing the association between body dissatisfaction and two contemporary measures of positive body image among 247 Black college-bound older adolescent females. We further tested whether possessing a higher body mass index (BMI) would strengthen these associations. Self-reported height and weight were used to calculate BMI. Respondents also completed a culturally-sensitive figure rating scale along with assessments of body appreciation and body image flexibility. Results indicated a robust positive association between the two measures of positive body image; BMI was the strongest predictor of both body appreciation and body image flexibility with body size discrepancy (current minus ideal) contributing incremental variance to both models tested. Implications for improving our understanding of the association between positive and negative body image and bolstering positive body image to promote health-protective behaviors among Black young women at this developmental juncture are discussed. PMID:25079011

  13. Historical time in the age of big data: Cultural psychology, historical change, and the Google Books Ngram Viewer.

    Science.gov (United States)

    Pettit, Michael

    2016-05-01

    Launched in 2010, the Google Books Ngram Viewer offers a novel means of tracing cultural change over time. This digital tool offers exciting possibilities for cultural psychology by rendering questions about variation across historical time more quantitative. Psychologists have begun to use the viewer to bolster theories about a historical shift in the United States from a more collectivist to individualist form of selfhood and society. I raise 4 methodological cautions about the Ngram Viewer's use among psychologists: (a) the extent to which print culture can be taken to represent culture as a whole, (b) the difference between viewing the past in terms of trends versus events, (c) assumptions about the stability of a word's meaning over time, and (d) inconsistencies in the scales and ranges used to measure change over time. The aim is to foster discussion about the standards of evidence needed for incorporating historical big data into empirical research. (PsycINFO Database Record PMID:27100927

  14. Clean Energy Manufacturing: U.S. Competitiveness and State Policy Strategies (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Lantz, E.

    2014-02-01

    The capital intensive nature of clean energy technologies suggests that manufacturing clean energy equipment has the potential to support state and local economic development efforts. However, manufacturing siting decisions tend to be complex and multi-variable decision processes that require in-depth knowledge of specific markets, the logistical requirements of a given technology, and insight into global clean tech trends. This presentation highlights the potential of manufacturing in supporting economic development opportunities while also providing examples of the financial considerations affecting manufacturing facility siting decisions for wind turbine blades and solar PV. The presentation also includes discussion of other more qualitative drivers of facility siting decisions as gleaned from NREL industry interviews and discusses strategies state and local policymakers may employee to bolster their chances of successfully attracting clean energy manufacturers to their localities.

  15. DECREASING INDIRECT FISCAL PRESSURE – ESSENTIAL TOOL FOR COMPETITIVENESS ENHANCING OF ROMANIA’S TOURISM SECTOR

    Directory of Open Access Journals (Sweden)

    Maria Loredana POPESCU

    2015-07-01

    Full Text Available Present condition of Romanian economy is (still! bad enough, given the yet existent (aftereffects of world economic and financial crisis, so that this economy badly needs bolstering up in any manner whatsoever; considering this perspective, and Romania’s tourism potential, Romania’s tourism sector can become a hub of/for economic recovery. But, in order to do this, Romania’s policymakers need not lose from sight Romania’s long term objectives, whilst trying to attain (just the short term ones. For the latter’ achievement fiscal policy is a main tool, but if this tool is used in extremis tourism sector will definitely suffer. On the other hand, it is also true fiscal policy, if used wisely, is more than able to be an essential tool with which one can enhance competitiveness of Romania’s tourism sector.

  16. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Jeffrey Schlom

    2012-12-01

    Full Text Available Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies.

  17. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Tucker, Jo A.; Jochems, Caroline [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Gulley, James L. [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Schlom, Jeffrey, E-mail: js141c@nih.gov; Tsang, Kwong Y. [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States)

    2012-12-11

    Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies.

  18. The pulsar planet production process

    Science.gov (United States)

    Phinney, E. S.; Hansen, B. M. S.

    1993-01-01

    Most plausible scenarios for the formation of planets around pulsars end with a disk of gas around the pulsar. The supplicant author then points to the solar system to bolster faith in the miraculous transfiguration of gas into planets. We here investigate this process of transfiguration. We derive analytic sequences of quasi-static disks which give good approximations to exact solutions of the disk diffusion equation with realistic opacity tables. These allow quick and efficient surveys of parameter space. We discuss the outward transfer of mass in accretion disks and the resulting timescale constraints, the effects of illumination by the central source on the disk and dust within it, and the effects of the widely different elemental compositions of the disks in the various scenarios, and their extensions to globular clusters. We point out where significant uncertainties exist in the appropriate grain opacities, and in the effect of illumination and winds from the neutron star.

  19. Housing as a Social Determinant of Health: Exploring the Relationship between Rent Burden and Risk Behaviors for Single Room Occupancy Building Residents.

    Science.gov (United States)

    Bowen, Elizabeth A; Mitchell, Christopher G

    2016-01-01

    A growing body of health determinants research recognizes that housing and health are intimately linked. This study explores the relationship between rent burden (the ratio of rent to income) and health risk behaviors among a sample of single room occupancy (SRO) building residents. Cross-sectional data were gathered from a sample of 162 residents living in privately owned, for-profit SROs in Chicago. Findings indicated that participants who had full rental subsidies and thus were designated in a no-rent-burden category were more likely to engage in risk behaviors including illicit drug use, having multiple sexual partners, and having sex without a condom, in comparison to participants with moderate or high-rent burdens. These findings suggest that interventions to increase housing stability and affordability and bolster reliable income sources (in addition to rental subsidies) may be key in reducing risk behaviors and improving health for vulnerably housed populations such as SRO residents. PMID:27167535

  20. A (Creative) Portrait of the Uncertain Individual: Self-Uncertainty and Individualism Enhance Creative Generation.

    Science.gov (United States)

    Rios, Kimberly; Markman, Keith D; Schroeder, Juliana; Dyczewski, Elizabeth A

    2014-05-22

    Building on findings that self-uncertainty motivates attempts to restore certainty about the self, particularly in ways that highlight one's distinctiveness from others, we show that self-uncertainty, relative to uncertainty in general, increases creative generation among individualists. In Studies 1 to 3, high (but not low) individualists performed better on a creative generation task after being primed with self-uncertainty as opposed to general uncertainty. In Study 4, this effect emerged only among those who were told that the task measured creative as opposed to analytical thinking, suggesting that the positive effects of self-uncertainty on performance are specific to tasks that bolster perceptions of uniqueness. In Study 5, self-uncertain individualists experienced a restoration of self-clarity after being induced to think about themselves as more (vs. less) creative. Implications for compensatory responses to self-uncertainty and factors that influence creativity are discussed. PMID:24854478

  1. Climate change and the insurance industry. The cost of increased risk and the impetus for action

    International Nuclear Information System (INIS)

    A convincing economic argument for taking action to prevent or ameliorate climate change has not developed because of both uncertainty about the degree of change and its timing. Recent costly weather-related catastrophes with consequent negative impacts on the insurance industry has made the insurance industry a potential advocate for slowing what has been identified as a causal factor in climate change: emissions of greenhouse gases. However, rising costs of claims, without a longer-term trend of such catastrophic losses, will make it difficult to present a strong case for taking costly economic action. Using the Black Scholes Option Pricing Model, it is shown that increasing levels of climate variability as embedded in the anticipated variability of damage to insured assets will have an immediate economic cost that could serve to bolster the argument for more immediate action. That cost is shown to be economically justified higher insurance premiums

  2. Curtis's cephaloscope: deafness and the making of surgical authority in London, 1816-1845.

    Science.gov (United States)

    Virdi-Dhesi, Jaipreet

    2013-01-01

    Aural surgery is a branch of nineteenth-century medicine and surgery providing specialized treatment for ear diseases. During the 1830s, faced with a "popular prejudice" against the curability of deafness as well as intraprofessional rivalries and continuous accusations of quackery, aurists found their surgical authority questioned and their field's value threatened. In an attempt to bolster aural surgery's reputation, in 1841, the aurist John Harrison Curtis (1778-1856) introduced his new diagnostic instrument, the cephaloscope, which could not only improve diagnosis but also provide approaches for regulating aural knowledge, thus strengthening aural surgery's authority. This article examines the motives underlying Curtis's introduction of the cephaloscope and the meanings it held for the occupational group at large.

  3. Suppression of tritium retention in remote areas of ITER by nonperturbative reactive gas injection.

    Science.gov (United States)

    Tabarés, F L; Ferreira, J A; Ramos, A; van Rooij, G; Westerhout, J; Al, R; Rapp, J; Drenik, A; Mozetic, M

    2010-10-22

    A technique based on reactive gas injection in the afterglow region of the divertor plasma is proposed for the suppression of tritium-carbon codeposits in remote areas of ITER when operated with carbon-based divertor targets. Experiments in a divertor simulator plasma device indicate that a 4  nm/min deposition can be suppressed by addition of 1  Pa·m³ s⁻¹ ammonia flow at 10 cm from the plasma. These results bolster the concept of nonperturbative scavenger injection for tritium inventory control in carbon-based fusion plasma devices, thus paving the way for ITER operation in the active phase under a carbon-dominated, plasma facing component background.

  4. Determinants of Scale Efficiency in the Brazilian Third-Party Logistics Industry from 2001 to 2009

    Directory of Open Access Journals (Sweden)

    Peter F. Wanke

    2012-01-01

    Full Text Available This article investigates the Brazilian third-party logistics (3PL sector which, increasingly competitive, offers clients a wide variety of services/information technologies in the quest to bolster efficiency. The main research objective is to determine which variables significantly impact 3PLs scale efficiency by applying two-stage DEA (Data Envelopment Analysis. Based on an unbalanced panel model, data from the annual study published by Revista Tecnologística (years 2001–2009 were analyzed. Results corroborate evidence in the literature that coordination mechanisms in the supply chain, supported by the availability of real time information and inventory synchronization, favor a more rational allocation of resources (inputs to client demands (outputs.

  5. Map Matching Based on Conditional Random Fields and Route Preference Mining for Uncertain Trajectories

    Directory of Open Access Journals (Sweden)

    Ming Xu

    2015-01-01

    Full Text Available In order to improve offline map matching accuracy of uncertain GPS trajectories, a map matching algorithm based on conditional random fields (CRF and route preference mining is proposed. In this algorithm, road offset distance and the temporal-spatial relationship between the sampling points are used as features of GPS trajectory in a CRF model, which integrates the temporal-spatial context information flexibly. The driver route preference is also used to bolster the temporal-spatial context when a low GPS sampling rate impairs the resolving power of temporal-spatial context in CRF, allowing the map matching accuracy of uncertain GPS trajectories to get improved significantly. The experimental results show that our proposed algorithm is more accurate than existing methods, especially in the case of a low-sampling-rate.

  6. Considering an affect regulation framework for examining the association between body dissatisfaction and positive body image in Black older adolescent females: does body mass index matter?

    Science.gov (United States)

    Webb, Jennifer B; Butler-Ajibade, Phoebe; Robinson, Seronda A

    2014-09-01

    The present study provided an initial evaluation of an affect regulation model describing the association between body dissatisfaction and two contemporary measures of positive body image among 247 Black college-bound older adolescent females. We further tested whether possessing a higher body mass index (BMI) would strengthen these associations. Self-reported height and weight were used to calculate BMI. Respondents also completed a culturally-sensitive figure rating scale along with assessments of body appreciation and body image flexibility. Results indicated a robust positive association between the two measures of positive body image; BMI was the strongest predictor of both body appreciation and body image flexibility with body size discrepancy (current minus ideal) contributing incremental variance to both models tested. Implications for improving our understanding of the association between positive and negative body image and bolstering positive body image to promote health-protective behaviors among Black young women at this developmental juncture are discussed.

  7. BACK IN TOWN

    Institute of Scientific and Technical Information of China (English)

    Wu Chunsi

    2012-01-01

    The United States has shifted its focus to the Asia-Pacific.This momentous move has sparked a heated debate in the Chinese media and academic community on a number of critical issues:Is the Obama administration's new AsiaPacific strategy in opposition to China? What will be the implications of this strategy? And how will China and the United States interact with each other in the Asia-Pacific region?New strategy After a decade focused on events in the Middle East,the United States has recently bolstered its presence in the Asia-Pacific,though many U.S.scholars argue the United States has never left the region.

  8. A Cosmic Ray Resolution to the Superbubble Energy-Crisis

    CERN Document Server

    Butt, Yousaf M

    2008-01-01

    Superbubbles (SBs) are amongst the greatest injectors of energy into the Galaxy, and have been proposed to be the acceleration site of Galactic cosmic rays. They are thought to be powered by the fast stellar winds and powerful supernova explosions of massive stars in dense stellar clusters and associations. Observations of the SB 'DEM L192' in the neighboring Large Magellenic Cloud (LMC) galaxy show that it contains only about one-third the energy injected by its constituent stars via fast stellar winds and supernovae. It is not yet understood where the excess energy is going, thus, the so-called 'energy crisis'. We show here that it is very likely that a significant fraction of the unaccounted for energy is being taken up in accelerating cosmic rays, thus bolstering the argument for the SB origin of cosmic rays.

  9. Assessment of collaboration in U.S. health care delivery: a perspective from systems theory.

    Science.gov (United States)

    McCovery, Jarred; Matusitz, Jonathan

    2014-01-01

    This analysis applies the core principles of systems theory to health care delivery in the United States. Particularly examined is the role of collaboration between health care agencies/organizations in the United States. This includes cooperation and teamwork among health professionals (i.e., nurses, technicians, physicians, and laboratory staff). By and large, systems theory posits that (a) all singular units within a system are interconnected and (b) the whole is more than the sum of its parts. This analysis identifies areas within the U.S. public health system where it is essential to embody elements of cooperation and collaboration, not only to bolster physical and financial support, but also to ensure a substantial impact within the community. PMID:25068610

  10. Lesbian, Gay, and Bisexual Identity as a Moderator of Relationship Functioning After Sexual Assault.

    Science.gov (United States)

    Gemberling, Tess M; Cramer, Robert J; Miller, Rowland S; Stroud, Caroline H; Noland, Ramona M; Graham, James

    2015-12-01

    Sexual assault is unfortunately common, especially among lesbian, gay, and bisexual (LGB) individuals. Yet, the associations of such victimization have not yet been extensively established in the areas of sexual identity and romantic relationship functioning. Accordingly, the present study examined the associations between lifetime sexual assault, LGB identity, and romantic relationship functioning in a sample of 336 LGB individuals. A history of sexual assault was associated with attachment anxiety and several sexual identity components (i.e., higher levels of acceptance concerns, identity uncertainty, internalized homonegativity, and identity superiority). Furthermore, an association of sexual assault and attachment avoidance was moderated by internalized homonegativity. Finally, a more secure LGB identity was associated with healthier romantic relationship functioning. Collectively, these findings are applicable to services for LGB sexual assault victims, suggesting the incorporation of treatment that bolsters LGB identity and couple functioning. Limitations and future directions are discussed. PMID:25516131

  11. Organizational Maturity in Competitive Intelligence – The Case of a Brazilian Financial Institution

    Directory of Open Access Journals (Sweden)

    Leonel Cezar Rodrigues

    2014-04-01

    Full Text Available This study aims at characterizing and identifying the degree of maturity in Competitive Intelligence (CI of a financial organization from a developing country, abyding by a maturity model in the literature. To do this research, the chosen method was the case study. Data were collected among 4 distinct áreas of the organization: Marketing, Physical Security; International Relations; and Risk management.  Main results indicate that two áreas show maturity in CI, level 1 – Informal. The othe two show degree of maturity in CI, level 2 – Formal. Conclusions of the study support coherence of criteria and elements that bolster the logic of the selected model and the decentralized structure of CI in the studied organization, showing, in an yet intuitive way, to hold an advanced CI operating model.

  12. March of the living, a holocaust educational tour: effect on adolescent Jewish identity.

    Science.gov (United States)

    Nager, Alan L; Pham, Phung; Gold, Jeffrey I

    2013-12-01

    March of the Living (MOTL) is a worldwide two-week trip for high school seniors to learn about the Holocaust by traveling to sites of concentration/death camps and Jewish historical sites in Poland and Israel. The mission statement of MOTL International states that participants will be able to "bolster their Jewish identity by acquainting them with the rich Jewish heritage in pre-war Eastern Europe." However, this claim has never been studied quantitatively. Therefore, 152 adolescents who participated in MOTL voluntarily completed an initial background questionnaire, a Jewish Identity Survey and a Global Domains Survey pre-MOTL, end-Poland and end-Israel. Results suggest that Jewish identity did not substantially increase overall or from one time period to the next. PMID:23801019

  13. Application and Utility of Psychodynamic Principles in Forensic Assessment.

    Science.gov (United States)

    Simopoulos, Eugene F; Cohen, Bruce

    2015-12-01

    Effective practice of forensic psychiatry is dependent on a clinical recognition and understanding of core psychodynamic principles and theory. Practice guidelines, rooted in the ethics-based imperative to strive for honesty and objectivity, demand that practitioners remain vigilant to the development of bias and appreciate interpersonal dynamics that may be re-enacted in the forensic setting. Although it is not feasible to maintain complete impartiality, especially when confronted with the nature of certain offenses, knowledge of both conscious and unconscious responses can bolster the intellectual integrity of the clinical assessment. The identification of defense mechanisms within both the evaluator and evaluee and attention to transference and countertransference are essential for an accurate conceptualization of an offender's psychological functioning, vulnerabilities, and risk of reoffense. In this article, we review psychodynamic concepts and their potential impact in the forensic setting and underscore interventions that may aid in the elucidation and management of these processes. PMID:26668219

  14. Compassion fatigue and burnout: what managers should know.

    Science.gov (United States)

    Slatten, Lise Anne; David Carson, Kerry; Carson, Paula Phillips

    2011-01-01

    Most health care employees experience and are bolstered by compassion satisfaction as they deal with patients in need. However, the more empathetic a health care provider is, the more likely he or she will experience compassion fatigue. Compassion fatigue is a negative syndrome that occurs when dealing with the traumatic experiences of patients, and examples of symptoms include intrusive thoughts, sleeping problems, and depression. Compassion fatigue is different from burnout. Compassion fatigue is a rapidly occurring disorder for primary health care workers who work with suffering patients, whereas burnout, a larger construct, is a slowly progressing disorder for employees who typically are working in burdensome organizational environments. Managers can mitigate problems associated with compassion fatigue with a number of interventions including patient reassignments, formal mentoring programs, employee training, and a compassionate organizational culture. With burnout, health care managers will want to focus primarily on chronic organizational problems. PMID:22042140

  15. Use your words!

    Science.gov (United States)

    Shapiro, Theodore

    2004-01-01

    "Use your words!" is a phrase admonishing preschoolers to divert their action-proneness to thought and language. Freud's injunction against acting out had a similar aim, placing control over drives in the domain of "inner language." The twenty-first-century psychoanalyst continues to employ models that depend on mentalization viewed from two angles-neural inhibition and social discourse. Psychoanalysts bolster their position by borrowing from the basic scientific work in each area. The recent focus on enactments, intersubjectivity, and social constructivism is reconsidered from an historical vantage point, as is the work that seeks to reconcile recent findings in neuroimaging and cognitive neuroscience. Freud's vision included a holistic hope that a comprehensive science of human beings might be achieved by understanding derived from biological inquiry and the artifacts of social and cultural narratives. The author's experience in both domains is recounted, and a new reconciliation of disparate approaches is offered in linguistic complementarity.

  16. Health care and family support systems of functionally impaired rural elderly men and women in Terengganu, Malaysia.

    Science.gov (United States)

    Tracy, M B; Tracy, P D

    1993-01-01

    This article examines the health and social support systems of a small survey sample of rural, low-income, functionally impaired elderly persons in the state of Terengganu, Malaysia. Increases in the number and proportion of the elderly are a growing concern, especially in rural areas where there are indications that traditional care givers (daughters) for the elderly are migrating to urban areas. The out-migration patterns in this survey, however, were less than expected. In general, the needs of the respondents are being met by multiple in-kind assistance from adult children, spouses, relatives, friends and neighbors bolstered by free government health care and cash assistance programs. The survey does raise serious concerns regarding the utilization of health care facilities by women, the negative impact of detrimental myths about aging, and the need for more visiting nurses and mobile clinics. PMID:24389755

  17. How to shape positive relationships in medical practices and hospitals.

    Science.gov (United States)

    Sotile, W M; Sotile, M O

    1999-01-01

    Managing workplace conflict is one of the most important, stressful, and time-consuming tasks faced by today's medical leaders. Poorly managed workplace conflict can alienate patients, demoralize staff, increase turnover, damage relationships with valued referral sources and third party carriers concerned about patient satisfaction, and lead medical practices to costly "corporate divorces." Physician executives cannot solve the problems caused by disruptive doctors simply by bolstering their own conflict management skills or by policing offenders. The larger contexts within which inappropriate workplace behavior occurs must also be assessed and addressed. The true leadership challenge is to intervene in ways that help to foster a "culture" of appropriate interpersonal dynamics throughout your organization. This requires learning to think and to intervene systematically. PMID:10557487

  18. Driving Their Way Out

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    China joined a worldwide effort to salvage its economy from being shattered by the devastating financial turmoil. Since the very beginning of this year, it has been working out a string of revitalization plans to bolster the nation’s backbone industries, including autos, iron and steel, shipbuilding, petrochemical, textile, equipment manufacturing, electronic and IT, nonferrous metals and light industries. By a rough estimation, those heavyweights jointly produce one third of China’s gross domestic product (GDP), create 80 percent of all added value of the industrial sector, and account for 35 percent of the nation’s tax revenue. In this issue, Beijing Review analyzes four of those plans, offering our readers a quick glimpse of how China intends to revive its flagging economy.

  19. Advanced Supersonic Nozzle Concepts: Experimental Flow Visualization Results Paired With LES

    Science.gov (United States)

    Berry, Matthew; Magstadt, Andrew; Stack, Cory; Gaitonde, Datta; Glauser, Mark; Syracuse University Team; The Ohio State University Team

    2015-11-01

    Advanced supersonic nozzle concepts are currently under investigation, utilizing multiple bypass streams and airframe integration to bolster performance and efficiency. This work focuses on the parametric study of a supersonic, multi-stream jet with aft deck. The single plane of symmetry, rectangular nozzle, displays very complex and unique flow characteristics. Flow visualization techniques in the form of PIV and schlieren capture flow features at various deck lengths and Mach numbers. LES is compared to the experimental results to both validate the computational model and identify limitations of the simulation. By comparing experimental results to LES, this study will help create a foundation of knowledge for advanced nozzle designs in future aircraft. SBIR Phase II with Spectral Energies, LLC under direction of Barry Kiel.

  20. Materials for Active Engagement in Nuclear and Particle Physics Courses

    Science.gov (United States)

    Loats, Jeff; Schwarz, Cindy; Krane, Ken

    2013-04-01

    Physics education researchers have developed a rich variety of research-based instructional strategies that now permeate many introductory courses. Carrying these active-engagement techniques to upper-division courses requires effort and is bolstered by experience. Instructors interested in these methods thus face a large investment of time to start from scratch. This NSF-TUES grant, aims to develop, test and disseminate active-engagement materials for nuclear and particle physics topics. We will present examples of these materials, including: a) Conceptual discussion questions for use with Peer Instruction; b) warm-up questions for use with Just in Time Teaching, c) ``Back of the Envelope'' estimation questions and small-group case studies that will incorporate use of nuclear and particle databases, as well as d) conceptual exam questions.

  1. Partial nephrectomy in a patient with a left ventricular assist device.

    Science.gov (United States)

    Manger, Jules P; Kern, John A; Krupski, Tracey L

    2011-01-01

    Left ventricular assist device (LVAD) use has increased as a bridge to heart transplant as well as destination therapy in patients with severe heart failure. Presence of LVAD is not a contraindication to noncardiac surgery but does present special challenges to the surgical, anesthesia, and cardiac teams. We present the case of a 40-year-old woman with idiopathic cardiomyopathy necessitating LVAD who underwent left partial nephrectomy for a renal mass. She had undergone three nondiagnostic percutaneous image-guided biopsies. Left partial nephrectomy was performed. Perioperative care was without incident due to careful oversight by a multidisciplinary team. Pathology revealed high-grade clear cell renal cell carcinoma (RCC) with negative margins. Polytetrafluoroethylene (PTFE) bolsters were misidentified six months postoperatively on computed tomography (CT) at an outside institution as a retained laparotomy sponge. This is, to our knowledge, the first report of a partial nephrectomy performed in a patient with LVAD. PMID:22606616

  2. Are effects of emotion expression on trait impressions mediated by babyfaceness? Evidence from connectionist modeling.

    Science.gov (United States)

    Zebrowitz, Leslie A; Kikuchi, Masako; Fellous, Jean-Marc

    2007-05-01

    Two studies provided evidence that bolsters the Marsh, Adams, and Kleck hypothesis that the morphology of certain emotion expressions reflects an evolved adaptation to mimic babies or mature adults. Study 1 found differences in emotion expressions' resemblance to babies using objective indices of babyfaceness provided by connectionist models that are impervious to overlapping cultural stereotypes about babies and the emotions. Study 2 not only replicated parallels between impressions of certain emotions and babies versus adults but also showed that objective indices of babyfaceness partially mediated impressions of the emotion expressions. babyface effects were independent of strong effects of attractiveness, and babyfaceness did not mediate impressions of happy expressions, to which the evolutionary hypothesis would not apply.

  3. Great expectations: autism spectrum disorder and induced pluripotent stem cell technologies.

    Science.gov (United States)

    Liu, Emily Yang; Scott, Christopher Thomas

    2014-04-01

    New applications of iPSC technology to research on complex idiopathic conditions raise several important ethical and social considerations for potential research participants and their families. In this short review, we examine these issues through the lens of emerging research on autism spectrum disorder (ASD). We begin by describing the current state of iPSC technology in research on ASD. Then we discuss how the social history of and current controversies in autism research combined with the emergence of autism-specific iPSC biobanks indicate an urgent need for researchers to clearly communicate the limitations and possibilities of iPSC research to ensure research participants have the ability to provide fully informed, voluntary consent. We conclude by offering recommendations to bolster informed consent for research involving iPSC biobanks, both in the specific context of ASD and more broadly.

  4. Stabilization of switched nonlinear systems with unstable modes

    CERN Document Server

    Yang, Hao; Cocquempot, Vincent

    2014-01-01

    This book provides its reader with a good understanding of the stabilization of switched nonlinear systems (SNS), systems that are of practical use in diverse situations: design of fault-tolerant systems in space- and aircraft; traffic control; and heat propagation control of semiconductor power chips. The practical background is emphasized throughout the book; interesting practical examples frequently illustrate the theoretical results with aircraft and spacecraft given particular prominence. Stabilization of Switched Nonlinear Systems with Unstable Modes treats several different subclasses of SNS according to the characteristics of the individual system (time-varying and distributed parameters, for example), the state composition of individual modes and the degree and distribution of instability in its various modes. Achievement and maintenance of stability across the system as a whole is bolstered by trading off between individual modes which may be either stable or unstable, or by exploiting areas of part...

  5. "To Bluff like a Man or Fold like a Girl?" – Gender Biased Deceptive Behavior in Online Poker

    Science.gov (United States)

    Palomäki, Jussi; Yan, Jeff; Modic, David; Laakasuo, Michael

    2016-01-01

    Evolutionary psychology suggests that men are more likely than women to deceive to bolster their status and influence. Also gender perception influences deceptive behavior, which is linked to pervasive gender stereotypes: women are typically viewed as weaker and more gullible than men. We assessed bluffing in an online experiment (N = 502), where participants made decisions to bluff or not in simulated poker tasks against opponents represented by avatars. Participants bluffed on average 6% more frequently at poker tables with female-only avatars than at tables with male-only or gender mixed avatars—a highly significant effect in games involving repeated decisions. Nonetheless, participants did not believe the avatar genders affected their decisions. Males bluffed 13% more frequently than females. Unlike most economic games employed exclusively in research contexts, online poker is played for money by tens of millions of people worldwide. Thus, gender effects in bluffing have significant monetary consequences for poker players. PMID:27383472

  6. The Concept of Alliance as an Image and Positioning Instrument for Institutions of Higher Learning

    Directory of Open Access Journals (Sweden)

    Víctor Manuel Alcántar Enríquez

    2004-05-01

    Full Text Available The present work provides a foundation for the concept of alliance which includes the ability of this to foster the university’s societal position as based on public perception of the institution. Accordingly, the work briefly addresses the development of the university’s collaboration with the productive sector, and emphasizes the need for institutions of higher learning to consider as well, those social sectors (including the government outside the realm of industry or technological expansion. The study concludes by affirming that alliance can become an effective instrument for promoting the university. It is therefore necessary to research the social perception of the university as a means of bolstering its relevance.

  7. First detection of Agrilus planipennis in Connecticut made by monitoring Cerceris fumipennis (Crabronidae colonies

    Directory of Open Access Journals (Sweden)

    Claire Rutledge

    2013-04-01

    Full Text Available Smoky winged beetle bandits, Cerceris fumipennis Say, digger wasps in the family Hymenoptera: Crabronidae: Cercerini, provision their underground nests with adult metallic wood-boring beetles (Coleoptera: Buprestidae. Researchers, as well as engaged community volunteers, in several states have monitored female wasps returning to their nests as a means to detect invasive buprestid species. In this paper, we report the first detection of emerald ash borer (Agrilus planipennis Fairemore, an invasive beetle responsible for killing millions of ash trees in North America, in Connecticut by C. fumipennis and discuss its relationship to A. planipennis survey efforts by other modalities in the state. We also report detections of A. planipennis by C. fumipennis in Illinois, New York and Ontario; all of which were made after it was known the beetle was in the area. These findings support the use of C. fumipennis as a biomonitoring tool and bolster the use of engaged volunteers.

  8. The Critical Role of Clerks in the Patient-Centered Medical Home.

    Science.gov (United States)

    Solimeo, Samantha L; Stewart, Greg L; Rosenthal, Gary E

    2016-07-01

    Research evaluating the effectiveness, function, and implementation of patient-centered medical homes (PCMHs) has found major socioprofessional transformations and contributions of primary care physicians and, to a lesser degree, nurses. Our longitudinal ethnographic research with teams implementing PCMH in Veterans Health Administration (VHA) primary care identifies the important but largely underutilized contributions of clerks to PCMH outcomes. Although the relationship of high-performing clerical staff to patient satisfaction is widely acknowledged, PCMH can be further enhanced by enabling clerks to use administrative tasks as conduits for investing in long-term personalized relationships with patients that foster trust in the PCMH and the broader health care organization. Such relationships are engendered through the care-coordination activities clerks perform, which may be bolstered by organizational investment in clerks as skilled health care team members. PMID:27401428

  9. Clarifying the link between childhood abuse history and psychopathic traits in adult criminal offenders.

    Science.gov (United States)

    Dargis, Monika; Newman, Joseph; Koenigs, Michael

    2016-07-01

    Childhood abuse is a risk factor for the development of externalizing characteristics and disorders, including antisocial personality disorder and psychopathy. However, the precise relationships between particular types of childhood maltreatment and subsequent antisocial and psychopathic traits remain unclear. Using a large sample of incarcerated adult male criminal offenders (n = 183), the current study confirmed that severity of overall childhood maltreatment was linked to severity of both psychopathy and antisocial personality disorder in adulthood. Moreover, this relationship was particularly strong for physical abuse and the antisocial facet of psychopathy. Sexual abuse history was uniquely related to juvenile conduct disorder severity, rather than adult psychopathy or antisocial behaviors. Additionally, there was a significantly stronger relationship between childhood maltreatment and juvenile conduct disorder than between childhood maltreatment and ASPD or psychopathy. These findings bolster and clarify the link between childhood maltreatment and antisocial behavior later in life. (PsycINFO Database Record PMID:26389621

  10. Stakeholders in Action

    DEFF Research Database (Denmark)

    often takes a primarily theoretical approach to the study of stakeholders and stakeholder management, the chapters in this book are first and foremost focused on the practical aspects of the field. Thus, through seven separate case studies, the book discusses how stakeholders are constructed implicitly...... and explicitly in corporate and institutional texts, investigating the possible consequences of these constructions for the communication and engagement between stakeholders and organisations....... of stakeholders and stakeholder roles, which may pave the way for dedicated management and communication strategies to enhance and bolster relationships. This volume follows in the footsteps of the many researchers who have studied and explored the field; however, as opposed to much current literature, which...

  11. Linking Europa's plume activity to tides, tectonics, and liquid water

    CERN Document Server

    Rhoden, Alyssa R; Roth, Lorenz; Retherford, Kurt

    2015-01-01

    Much of the geologic activity preserved on Europa's icy surface has been attributed to tidal deformation, mainly due to Europa's eccentric orbit. Although the surface is geologically young (30 - 80 Myr), there is little information as to whether tidally-driven surface processes are ongoing. However, a recent detection of water vapor near Europa's south pole suggests that it may be geologically active. Initial observations indicated that Europa's plume eruptions are time-variable and may be linked to its tidal cycle. Saturn's moon, Enceladus, which shares many similar traits with Europa, displays tidally-modulated plume eruptions, which bolstered this interpretation. However, additional observations of Europa at the same time in its orbit failed to yield a plume detection, casting doubt on the tidal control hypothesis. The purpose of this study is to analyze the timing of plume eruptions within the context of Europa's tidal cycle to determine whether such a link exists and examine the inferred similarities and...

  12. Replicating Cardiovascular Condition-Birth Month Associations

    Science.gov (United States)

    Li, Li; Boland, Mary Regina; Miotto, Riccardo; Tatonetti, Nicholas P.; Dudley, Joel T.

    2016-01-01

    Independent replication is vital for study findings drawn from Electronic Health Records (EHR). This replication study evaluates the relationship between seasonal effects at birth and lifetime cardiovascular condition risk. We performed a Season-wide Association Study on 1,169,599 patients from Mount Sinai Hospital (MSH) to compute phenome-wide associations between birth month and CVD. We then evaluated if seasonal patterns found at MSH matched those reported at Columbia University Medical Center. Coronary arteriosclerosis, essential hypertension, angina, and pre-infarction syndrome passed phenome-wide significance and their seasonal patterns matched those previously reported. Atrial fibrillation, cardiomyopathy, and chronic myocardial ischemia had consistent patterns but were not phenome-wide significant. We confirm that CVD risk peaks for those born in the late winter/early spring among the evaluated patient populations. The replication findings bolster evidence for a seasonal birth month effect in CVD. Further study is required to identify the environmental and developmental mechanisms. PMID:27624541

  13. Applications of Optical Microcavity Resonators in Analytical Chemistry.

    Science.gov (United States)

    Wade, James H; Bailey, Ryan C

    2016-06-12

    Optical resonator sensors are an emerging class of analytical technologies that use recirculating light confined within a microcavity to sensitively measure the surrounding environment. Bolstered by advances in microfabrication, these devices can be configured for a wide variety of chemical or biomolecular sensing applications. We begin with a brief description of optical resonator sensor operation, followed by discussions regarding sensor design, including different geometries, choices of material systems, methods of sensor interrogation, and new approaches to sensor operation. Throughout, key developments are highlighted, including advancements in biosensing and other applications of optical sensors. We discuss the potential of alternative sensing mechanisms and hybrid sensing devices for more sensitive and rapid analyses. We conclude with our perspective on the future of optical microcavity sensors and their promise as versatile detection elements within analytical chemistry.

  14. Curtis's cephaloscope: deafness and the making of surgical authority in London, 1816-1845.

    Science.gov (United States)

    Virdi-Dhesi, Jaipreet

    2013-01-01

    Aural surgery is a branch of nineteenth-century medicine and surgery providing specialized treatment for ear diseases. During the 1830s, faced with a "popular prejudice" against the curability of deafness as well as intraprofessional rivalries and continuous accusations of quackery, aurists found their surgical authority questioned and their field's value threatened. In an attempt to bolster aural surgery's reputation, in 1841, the aurist John Harrison Curtis (1778-1856) introduced his new diagnostic instrument, the cephaloscope, which could not only improve diagnosis but also provide approaches for regulating aural knowledge, thus strengthening aural surgery's authority. This article examines the motives underlying Curtis's introduction of the cephaloscope and the meanings it held for the occupational group at large. PMID:24096558

  15. Republic of Moldova: between the Eropean Union and Commonwealth of Independent States

    Directory of Open Access Journals (Sweden)

    Yuri Josanu

    2012-08-01

    Full Text Available Moldova is the second smallest and the most densely populated of the NIS. It began the arduous task of building a democratic nation and market-based economy as it faced ethnic conflicts and the social hardships accompanying economic and political transformation. The country has pushed ahead with economic policy reform as a model of change among NIS countries. Moldova is also considered one of the top NIS performers in democratic development. Internal political tensions over the pace of reforms have delayed progress in land privatization and fiscal improvement. Underlying all of these issues is the festering problem of Transdniester where ethnic Russians, bolstered by the presence of Russian troops, thus denying Moldova control over significant industrial assets.

  16. Modeling of nanotoxicity molecular interactions of nanomaterials with bionanomachines

    CERN Document Server

    Zhou, Ruhong

    2015-01-01

    This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines. It lays out the fundamentals of nanotoxicity modeling for an array of nanomaterial systems, ranging from carbon-based nanoparticles to noble metals, metal oxides, and quantum dots. The author illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling approaches can be applied to bolster our understanding of many important aspects of this critical nanotoxicity issue. Each chapter is organized by types of nanomaterials for practicality, making this an ideal book for senior undergraduate students, graduate students, and researchers in nanotechnology, chemistry, physics, molecular biology, and computer science. It is also of interest to academic and industry professionals who work on nanodrug delivery and related biomedical applications, and aids readers in their biocompatibility assessment efforts in the coming age of nanotechnology...

  17. Freehand 'figure 4' technique for tibial intramedullary nailing: introduction of technique and review of 87 cases.

    Science.gov (United States)

    Granville-Chapman, J; Nawaz, S Z; Trompeter, A; Newman, K J; Elliott, D S

    2014-10-01

    Intramedullary nailing of tibial fractures is commonplace, and freehand operative techniques are increasingly popular. The standard freehand method has the knee of the injured leg flexed over a radiolucent bolster. This requires the theatre fluoroscope to swing from antero-posterior to lateral position several times. Furthermore, guide wire placement, reaming and nail insertion are all performed well above most surgeons' shoulder height. Alternatively the leg is hung over the edge of the table, and the assistant must crouch and hold the leg until the nail is passed beyond the fracture. We describe a freehand figure 4 position technique for tibial nailing which is easier both for the surgeons and the radiographer, and present a series of 87 consecutive cases utilising this method. PMID:24013812

  18. Science and Technology Review January/February 2011

    International Nuclear Information System (INIS)

    This month's issue has the following articles: (1) World's Most Intense X-Ray Laser Focuses on Livermore Science - Commentary by William H. Goldstein; (2) Groundbreaking Science with the World's Brightest X Rays - Experiments with x rays of unparalleled brightness and extremely short duration aim to reveal new information about atoms and molecules in motion; (3) From Data to Discovery - Ongoing control system enhancements at the National Ignition Facility bolster the understanding of experimental data and keep the system performing at its peak; (4) The Sun in All Its Splendor - Onboard the Solar Dynamics Observatory, Livermore-developed multilayer mirrors are enabling unprecedented full-disk, high-resolution images of the Sun; and (5) Drilling Deep into Plant Veins - A novel combination of imaging techniques is being used to understand the three-dimensional architecture of plant cell walls.

  19. Improving HCAHPS Scores with Advances in Digital Radiography.

    Science.gov (United States)

    Matthews, Marianne; Cretella, Gregg; Nicholas, William

    2016-01-01

    The imaging department can be instrumental in contributing to a healthcare facility's ability to succeed in this new era of competition. Advances in DR technology can improve patient perceptions in the imaging department by improving efficiencies and outcomes which, in turn, can ultimately bolster overall HCAHPS scores. Specific areas for improved scores by utilization of DR include nurse communication, doctor communication, pain management, and communication about medication. Value based purchasing brought with it a mandate for hospitals to track key metrics, which requires an investment in time, tools, and human resources. However, this mandate also presents hospitals and imaging departments, with an opportunity to leverage those very metrics to better market their facilities. PMID:26939298

  20. The Individuals With Disabilities Education Act (IDEA) for Children With Special Educational Needs.

    Science.gov (United States)

    Lipkin, Paul H; Okamoto, Jeffrey

    2015-12-01

    The pediatric health care provider has a critical role in supporting the health and well-being of children and adolescents in all settings, including early intervention (EI), preschool, and school environments. It is estimated that 15% of children in the United States have a disability. The Individuals with Disabilities Education Act entitles every affected child in the United States from infancy to young adulthood to a free appropriate public education through EI and special education services. These services bolster development and learning of children with various disabilities. This clinical report provides the pediatric health care provider with a summary of key components of the most recent version of this law. Guidance is also provided to ensure that every child in need receives the EI and special education services to which he or she is entitled. PMID:26620061

  1. Commentary on: Are we overpathologizing everyday life? A tenable blueprint for behavioral addiction research. On the slippery slopes: The case of gambling addiction.

    Science.gov (United States)

    Clark, Luke

    2015-09-01

    Billieux et al. (2015) propose that the recent proliferation of behavioral addictions has been driven by deficiencies in the underlying research strategy. This commentary considers how pathological gambling (now termed gambling disorder) traversed these challenges to become the first recognized behavioral addiction in the DSM-5. Ironically, many similar issues continue to exist in research on gambling disorder, including question-marks over the validity of tolerance, heterogeneity in gambling motives, and the under-specification of neuroimaging biomarkers. Nevertheless, I contend that the case for gambling disorder as a behavioral addiction has been bolstered by the existence of clear and consistent functional impairment (primarily in the form of debt), coupled with the development of a public health approach that has given emphasis to product features (i.e. the structural characteristics of gambling forms) as much as individual dispositions (the 'addictive personality'). PMID:26551898

  2. A Change for the Better

    DEFF Research Database (Denmark)

    Rozendal, Arjan; Lim, Eric T. K.; Tan, Chee-Wee

    2015-01-01

    Investments in information technology will only yield dividends whenever technological spending complements corporate objectives, a phenomenon termed as business-IT alignment within extant literature. Synthesizing extant literature on business-IT alignment and organizational change, this paper...... argues for effective change management as a means for organizations to realize business-IT alignment. Findings from a grounded theory study revealed that having clear assessment criteria, promoting information exchange, getting managers to act as role models, expanding the involvement and participation...... of employees in decision making as well as drawing on positive collaborative experiences in the past bolster the success of change initiatives for realizing business-IT alignment. Conversely, pursuing partisan interest at the expense of the organization, speaking different professional languages, displaying...

  3. "Abomination"--life as a Bible belt gay.

    Science.gov (United States)

    Barton, Bernadette

    2010-01-01

    Drawing on observation, autoethnography, and audio-taped interviews, this article explores the religious backgrounds and experiences of Bible Belt gays. In the Bible Belt, Christianity is not confined to Sunday worship. Christian crosses, messages, paraphernalia, music, news, and attitudes permeate everyday settings. Consequently, Christian fundamentalist dogma about homosexuality-that homosexuals are bad, diseased, perverse, sinful, other, and inferior-is cumulatively bolstered within a variety of other social institutions and environments in the Bible Belt. Of the 46 lesbians and gay men interviewed for this study (age 18-74 years), most describe living through spirit-crushing experiences of isolation, abuse, and self-loathing. This article argues that the geographic region of the Bible Belt intersects with religious-based homophobia. Informants explained that negative social attitudes about homosexuality caused a range of harmful consequences in their lives including the fear of going to hell, depression, low self-esteem, and feelings of worthlessness.

  4. The theological paraphrasing of history: The Exodus tradition in the Wisdom of Solomon

    Directory of Open Access Journals (Sweden)

    Hendrik L. Bosman

    2012-11-01

    Full Text Available This study of the reinterpretation of the exodus tradition in the Wisdom of Solomon investigated the possibility that the reinterpretation entailed the alignment of history and wisdom. To come to grips with this alignment, attention had to be paid to its Greco-Roman context, whilst also taking into consideration the literary and theological structure of the Wisdom of Solomon, as well as its rhetoric and genre. In a theologically creative manner, Wisdom (as divine personification and history (as memories of salvation during the Exodus were combined in the Wisdom of Solomon to convince the Jews in the diaspora that justice would prevail – not only in this life but also thereafter. By means of poetic imagery, rhetorical skill, historical reinterpretation and imaginative wisdom theology, religious identity were not only bolstered to resist a dominant Greco-Roman culture but also to develop a positive view of creation according to the values of wisdom exemplified by the reinterpreted Exodus traditions.

  5. Using communities that care for community child maltreatment prevention.

    Science.gov (United States)

    Salazar, Amy M; Haggerty, Kevin P; de Haan, Benjamin; Catalano, Richard F; Vann, Terri; Vinson, Jean; Lansing, Michaele

    2016-03-01

    The prevention of mental, emotional, and behavioral (MEB) disorders among children and adolescents is a national priority. One mode of implementing community-wide MEB prevention efforts is through evidence-based community mobilization approaches such as Communities That Care (CTC). This article provides an overview of the CTC framework and discusses the adaptation process of CTC to prevent development of MEBs through preventing child abuse and neglect and bolstering child well-being in children aged 0 to 10. Adaptations include those to the intervention itself as well as those to the evaluation approach. Preliminary findings from the Keeping Families Together pilot study of this evolving approach suggest that the implementation was manageable for sites, and community board functioning and community adoption of a science-based approach to prevention in pilot sites looks promising. Implications and next steps are outlined. (PsycINFO Database Record PMID:26963184

  6. Laser Tunnel Ionization from Multiple Orbitals in HCl

    Science.gov (United States)

    Akagi, H.; Otobe, T.; Staudte, A.; Shiner, A.; Turner, F.; Dörner, R.; Villeneuve, D. M.; Corkum, P. B.

    2009-09-01

    Tunneling, one of the most striking manifestations of quantum mechanics, influences the electronic structure of many molecules and solids and is responsible for radioactive decay. Much of the interaction of intense light pulses with matter commences with electrons tunneling from atoms or molecules to the continuum. Until recently, this starting point was assumed to be the highest occupied orbital of a given system. We have now observed tunneling from a lower-lying state in hydrogen chloride (HCl). Analyzing two independent experimental observables allowed us to isolate (via fragment ions), identify (via molecular frame photoelectron angular distributions), and, with the help of ab initio simulations, quantify the contribution of lower-lying orbitals to the total and angle-dependent tunneling current of the molecule. Our results bolster the emerging tenet that the coherent interaction between different orbitals—which can amplify the impact of lower orbitals—must be considered in tunneling processes.

  7. EXPORTS, FOREIGN DIRECT INVESTMENT AND ECONOMIC GROWTH: EMPIRICAL EVIDENCE FROM MALAYSIA (1971-2013

    Directory of Open Access Journals (Sweden)

    Muhammad Haseeb

    2014-01-01

    Full Text Available The main objective of this study is to empirically investigate the relationship between exports, Foreign Direct Investment (FDI and the economic growth in Malaysia. Records of annual time series data from the year 1971 till 2013 have been utilized for this purpose. Upon testing the data for stationarity, the Auto Regressive Distributed Lag (ARDL model has been applied for the purpose of empirical investigation. The empirical results indicate that the productivity factor and externality effect of exports on the non-export sector are found to be statistically, positively significant, with the exports also having a positive impact on the economic growth and FDI of the country. The results support Exports Led Growth (ELG and FDI-Led economic Growth (FLG in Malaysia. The finding further suggests that Malaysia should continuous pursue exports promotion and a liberal investment economic policy in order to maintain and bolster overall economic growth.

  8. Playing Games with the Quantum Three-Body Problem

    CERN Document Server

    Biswas, T

    2004-01-01

    Quantum mechanics courses focus mostly on its computational aspects. This alone does not provide the same depth of understanding as most physicists have of classical mechanics. The understanding of classical mechanics is significantly bolstered by the intuitive understanding that one acquires through the playing of games like baseball at an early age. It would be good to have similar games for quantum mechanics. However, real games that involve quantum phenomena directly are impossible. So, computer simulated games are good alternatives. Here a computer game involving three interacting quantum particles is discussed. It is hoped that such games played at an early age will provide the intuitive background for a better understanding of quantum mechanics at a later age.

  9. A novel way to treat skin tears.

    Science.gov (United States)

    Moradian, Scott; Klapper, Andrew M

    2016-04-01

    Skin tears are one of the most commonly treated wounds in the elderly population. In their most basic form, they are essentially traumatic random pattern flaps. We postulate that the injured blood flow to these skin flaps should be ignored and the tissue should be treated as a skin graft. A case report is presented of an 86-year-old female with an 8 × 3·5 cm skin tear to her right upper extremity after a hip fracture. In addition to conventional wound closure strips re-approximating the tissues, a disposable negative pressure wound therapy device was placed to act as bolster. Upon its removal on day 5, the opposed skin tear tissue was found to be 100% viable. We therefore propose that this update may be an improvement over classical skin tear treatments and should be followed up with a case series.

  10. To discover or to create: metaphors and the true self.

    Science.gov (United States)

    Schlegel, Rebecca J; Vess, Matthew; Arndt, Jamie

    2012-08-01

    Three studies examined how endorsement of self-discovery and self-creation metaphors influences belief in the true self and its use as meaning source. It was hypothesized that discovery metaphors contribute to belief in the true self and bolster the relationship between true self-knowledge and meaning. Study 1 supported the hypothesis that discovery is positively associated with belief in the true self among a sample of college students (N = 311). Studies 2 and 3 extended the analysis by showing that the discovery metaphor also facilitates perceptions of meaning and the use of the true self specifically as a source of meaning in a second sample of college students (N = 75) as well as an adult sample of university employees (N = 173). Implications for understanding what enables the true self to infuse life with meaning, as well as an individual differences approach to metaphoric cognition, are discussed.

  11. Little Ice Age wetting of interior Asian deserts and the rise of the Mongol Empire

    Science.gov (United States)

    Putnam, Aaron E.; Putnam, David E.; Andreu-Hayles, Laia; Cook, Edward R.; Palmer, Jonathan G.; Clark, Elizabeth H.; Wang, Chunzeng; Chen, Feng; Denton, George H.; Boyle, Douglas P.; Bassett, Scott D.; Birkel, Sean D.; Martin-Fernandez, Javier; Hajdas, Irka; Southon, John; Garner, Christopher B.; Cheng, Hai; Broecker, Wallace S.

    2016-01-01

    The degree to which warming of the planet will alter Asia's water resources is an important question for food, energy, and economic security. Here we present geological evidence, underpinned by radiometric dating and dendrochronology, and bolstered by hydrological modeling, indicating that wetter-than-present conditions characterized the core of the inner Asian desert belt during the Little Ice Age, the last major Northern Hemispheric cold spell of the Holocene. These wetter conditions accompanied northern mid-latitude cooling, glacier expansion, a strengthened/southward-shifted boreal jet, and weakened south Asian monsoons. We suggest that southward migration of grasslands in response to these wetter conditions aided the spread of Mongol Empire steppe pastoralists across Asian drylands. Conversely, net drying over the 20th century has led to drought that is unprecedented for the past ∼830 years, and that could intensify with further heating of the Asian continent.

  12. "Abomination"--life as a Bible belt gay.

    Science.gov (United States)

    Barton, Bernadette

    2010-01-01

    Drawing on observation, autoethnography, and audio-taped interviews, this article explores the religious backgrounds and experiences of Bible Belt gays. In the Bible Belt, Christianity is not confined to Sunday worship. Christian crosses, messages, paraphernalia, music, news, and attitudes permeate everyday settings. Consequently, Christian fundamentalist dogma about homosexuality-that homosexuals are bad, diseased, perverse, sinful, other, and inferior-is cumulatively bolstered within a variety of other social institutions and environments in the Bible Belt. Of the 46 lesbians and gay men interviewed for this study (age 18-74 years), most describe living through spirit-crushing experiences of isolation, abuse, and self-loathing. This article argues that the geographic region of the Bible Belt intersects with religious-based homophobia. Informants explained that negative social attitudes about homosexuality caused a range of harmful consequences in their lives including the fear of going to hell, depression, low self-esteem, and feelings of worthlessness. PMID:20391006

  13. Innovation adoption as facilitated by a change-oriented workplace.

    Science.gov (United States)

    Becan, Jennifer E; Knight, Danica K; Flynn, Patrick M

    2012-03-01

    One of the unique contributions of this study is a glimpse into the process by which counselors decide to try new innovations in their clinical work. Data were collected from 421 counseling staff from 71 outpatient treatment programs in 4 U.S. regions. Using hierarchical linear modeling, results reveal that the propensity to adopt workshop-based interventions is facilitated by two important mechanisms: (a) an innovative organization with creative leadership and (b) change-oriented staff attributes (i.e., seeking professional growth, efficacy, adaptability, and influence on others). Innovative leaders and a climate receptive to change also bolster the development of these change-oriented attributes. One implication of these findings is the cascading effect of leaders' support of innovative thinking and action resulting in employees strengthening their own adaptive skills and carrying this innovative thinking into individual adoption.

  14. Smartphones in Surgery

    Directory of Open Access Journals (Sweden)

    Ara A. Salibian

    2011-01-01

    Full Text Available Smartphones have the capability of enhancing many aspects of the continuum of surgical care by providing an efficient means of multimedia communication among surgeons and healthcare personnel. The ability for mobile Internet and email access, along with features such as built-in cameras and video calling, allow surgeons to rapidly access, send and receive patient information without being restricted by issues of connectivity. Smartphones create an unrestricted network of data sharing, improving the flexibility of patient consultation, timeliness of preoperative preparation, efficiency of post-operative care and the effectiveness of a surgical team. Furthermore, smartphones provide mobile access to a multitude of surgical resources to bolster continued surgical education. This article presents a review of the current literature on the utilizations of smartphones in surgery, discusses their benefits and limitations, and addresses the possibility of incorporating smartphones into the protocol of surgical care.

  15. Spliced

    DEFF Research Database (Denmark)

    Addison, Courtney Page

    2016-01-01

    Human gene therapy (HGT) aims to cure disease by inserting or editing the DNA of patients with genetic conditions. Since foundational genetic techniques came into use in the 1970s, the field has developed to the point that now three therapies have market approval, and over 1800 clinical trials have...... been initiated. In this article I present a brief history of HGT, showing how the ethical and practical viability of the field was achieved by key scientific and regulatory actors. These parties carefully articulated gene therapy’s scope, limiting it to therapeutic interventions on somatic cells......, and cultivated alliances and divisions that bolstered the field’s legitimacy. At times these measures faltered, and then practitioners and sometimes patients would invoke an ethical imperative, posing gene therapy as the best solution to life and death problems. I suggest that we consider how boundary...

  16. Continuity, divergence and the evolution of brain language pathways

    Directory of Open Access Journals (Sweden)

    James eRilling

    2012-01-01

    Full Text Available Recently, the assumption of evolutionary continuity between humans and non-human primates has been used to bolster the hypothesis that human language is mediated especially by the ventral extreme capsule pathway that mediates auditory object recognition in macaques. Here, we argue for the importance of evolutionary divergence in understanding brain language evolution. We present new comparative data reinforcing our previous conclusion that the dorsal arcuate fasciculus pathway was more significantly modified than the ventral extreme capsule pathway in human evolution. Twenty-six adult human and twenty six adult chimpanzees were imaged with diffusion-weighted MRI and probabilistic tractography was used to track and compare the dorsal and ventral language pathways. Based on these and other data, we argue that the arcuate fasciculus is likely to be the pathway most essential for higher-order aspects of human language such as syntax and lexical-semantics.

  17. [Possibilities of inclusion of the partner in deliveries in public institutions].

    Science.gov (United States)

    Brüggemann, Odaléa Maria; Ebsen, Erika Simas; Ebele, Romana Raquel; Batista, Bruna Daniela

    2016-08-01

    Qualitative research, with an exploratory and descriptive approach, was conducted between September 2011 and February 2012, aimed at revealing the possibility of inclusion of the partner in deliveries in institutions that currently restrict their presence. Twelve nurses responsible for obstetric centers and five technical directors of health institutions of Santa Catarina, who did not allow or infrequently allowed the presence of the partner during delivery, were interviewed. Data were analyzed using Bardin Content Analysis, with the support of ATLAS.ti software. The possibilities of including the partner are permitted in three categories: I - Labor pain process; II - Receptiveness of professionals to the partner; and III - Empowerment of patients. Although some institutions limit the presence of the partner, they describe aspects that favor their inclusion. From the results presented, it is suggested that these enabling elements could be bolstered with management strategies, ongoing learning and intersectoral actions. PMID:27557028

  18. Lesbian, Gay, and Bisexual Identity as a Moderator of Relationship Functioning After Sexual Assault.

    Science.gov (United States)

    Gemberling, Tess M; Cramer, Robert J; Miller, Rowland S; Stroud, Caroline H; Noland, Ramona M; Graham, James

    2015-12-01

    Sexual assault is unfortunately common, especially among lesbian, gay, and bisexual (LGB) individuals. Yet, the associations of such victimization have not yet been extensively established in the areas of sexual identity and romantic relationship functioning. Accordingly, the present study examined the associations between lifetime sexual assault, LGB identity, and romantic relationship functioning in a sample of 336 LGB individuals. A history of sexual assault was associated with attachment anxiety and several sexual identity components (i.e., higher levels of acceptance concerns, identity uncertainty, internalized homonegativity, and identity superiority). Furthermore, an association of sexual assault and attachment avoidance was moderated by internalized homonegativity. Finally, a more secure LGB identity was associated with healthier romantic relationship functioning. Collectively, these findings are applicable to services for LGB sexual assault victims, suggesting the incorporation of treatment that bolsters LGB identity and couple functioning. Limitations and future directions are discussed.

  19. Land use and management change under climate change adaptation and mitigation strategies: a U.S. case study

    Science.gov (United States)

    Mu, Jianhong E.; Wein, Anne; McCarl, Bruce

    2015-01-01

    We examine the effects of crop management adaptation and climate mitigation strategies on land use and land management, plus on related environmental and economic outcomes. We find that crop management adaptation (e.g. crop mix, new species) increases Greenhouse gas (GHG) emissions by 1.7 % under a more severe climate projection while a carbon price reduces total forest and agriculture GHG annual flux by 15 % and 9 %, respectively. This shows that trade-offs are likely between mitigation and adaptation. Climate change coupled with crop management adaptation has small and mostly negative effects on welfare; mitigation, which is implemented as a carbon price starting at $15 per metric ton carbon dioxide (CO2) equivalent with a 5 % annual increase rate, bolsters welfare carbon payments. When both crop management adaptation and carbon price are implemented the effects of the latter dominates.

  20. An Account of ... William Cullen: John Thomson and the Making of a Medical Biography.

    Science.gov (United States)

    Shuttleton, David E

    2014-01-01

    John Thomson's An Account of the Life, Lectures and Writings of William Cullen (1832; 1859) remains a primary source for the career of the most influential academic physician in eighteenth-century Scotland and is also a significant work of medical history. But this multi-authored text, begun around 1810 by the academic surgeon, John Thomson, but only completed in 1859 by Dr David Craigie, has its own complex history. This chapter addresses what this history can reveal about the development of medical biography as a literary genre. It argues that the Account is a hybrid work shaped by a complex array of practical, domestic, intellectual, and professional pressures, as Thomson, in seeking to bolster his own career, was caught between the demands of Cullen's children for a traditional "Life" and his own more theoretical and socio-cultural interests.

  1. Morphological communication: exploiting coupled dynamics in a complex mechanical structure to achieve locomotion

    Science.gov (United States)

    Rieffel, John A.; Valero-Cuevas, Francisco J.; Lipson, Hod

    2010-01-01

    Traditional engineering approaches strive to avoid, or actively suppress, nonlinear dynamic coupling among components. Biological systems, in contrast, are often rife with these dynamics. Could there be, in some cases, a benefit to high degrees of dynamical coupling? Here we present a distributed robotic control scheme inspired by the biological phenomenon of tensegrity-based mechanotransduction. This emergence of morphology-as-information-conduit or ‘morphological communication’, enabled by time-sensitive spiking neural networks, presents a new paradigm for the decentralized control of large, coupled, modular systems. These results significantly bolster, both in magnitude and in form, the idea of morphological computation in robotic control. Furthermore, they lend further credence to ideas of embodied anatomical computation in biological systems, on scales ranging from cellular structures up to the tendinous networks of the human hand. PMID:19776146

  2. Costs of global climate protection

    International Nuclear Information System (INIS)

    This paper discusses the cost implications of the air pollution abatement recommendations contained in a recently published IPSEP (International Project for Sustainable Energy Paths) study on the feasibility of the abatement of carbon dioxide emissions deemed significantly responsible for the greenhouse effect and its associated negative impacts on this planet's climatic equilibrium. The air pollution abatement strategies are to be enforced in five highly industrialized European countries - Germany, France, Great Britain, Italy and Holland. The study's overall results indicate the feasibility of 50% reductions in carbon dioxide emissions within the next 30 years even with a more than doubling of GNP's and a contemporaneous phase-out of nuclear power production, and all this taking place in a cost effective way and with increased employment. In addition, IPSEP's report states that the implementation of effective program management strategies would bolster Western Europe's competitiveness on a global scale

  3. FIPSER: Performance Study of a Readout Concept With Few Digitization Levels for Fast Signals

    CERN Document Server

    Limyansky, Brent; Cressler, John D; Otte, Adam Nepomuk; Taboada, Ignacio; Ulusoy, Cagri

    2016-01-01

    We discuss the performance of a readout system, Fixed Pulse Shape Efficient Readout (FIPSER), to digitize signals from detectors with a fixed pulse shape. In this study we are mainly interested in the readout of fast photon detectors like photomultipliers or Silicon photomultipliers. But the concept can be equally applied to the digitization of other detector signals. FIPSER is based on the flash analog to digital converter (FADC) concept, but has the potential to lower costs and power consumption by using an order of magnitude fewer discrete voltage levels. Performance is bolstered by combining the discretized signal with the knowledge of the underlying pulse shape. Simulated FIPSER data was reconstructed with two independent methods. One using a maximum likelihood method and the other using a modified chisquared test. Both methods show that utilizing 12 discrete voltage levels with a sampling rate of 4 samples per full width half maximum (FWHM) of the pulse achieves an amplitude resolution that is better th...

  4. Language exposure facilitates talker learning prior to language comprehension, even in adults.

    Science.gov (United States)

    Orena, Adriel John; Theodore, Rachel M; Polka, Linda

    2015-10-01

    Adults show a native language advantage for talker identification, which has been interpreted as evidence that phonological knowledge mediates talker learning. However, infants also show a native language benefit for talker discrimination, suggesting that sensitivity to linguistic structure due to systematic language exposure promotes talker learning, even in the absence of functional phonological knowledge or language comprehension. We tested this hypothesis by comparing two groups of English-monolingual adults on their ability to learn English and French voices. One group resided in Montréal with regular exposure to spoken French; the other resided in Storrs, Connecticut and did not have French exposure. Montréal residents showed faster learning and better retention for the French voices compared to their Storrs-residing peers. These findings demonstrate that systematic exposure to a foreign language bolsters talker learning in that language, expanding the gradient effect of language experience on talker learning to perceptual learning that precedes sentence comprehension. PMID:26113447

  5. Psychocapital and Shangri-Las: How happiness became both a means and end to governmentality

    Directory of Open Access Journals (Sweden)

    F. Mckay

    2013-11-01

    Full Text Available In this paper a paradox is revealed in the politics of well-being over the means and ends of happiness. That paradox, in brief, is that although happiness is argued to be the ultimate end of all governmentality, in order to serve as that end, it first needs to be translated into a means for bolstering the economy, for only that way can a teleology of happiness gain a foothold in a world which prioritizes economic growth as an end in itself. To show this the paper gives a history of subjective well-being (SWB research, and contrasts it with the politics of happiness in the UK, where SWB has in the past decade been translated into a discourse around the psychological wealth of the nation via the concepts of mental capital (MC and mental well-being (MWB.

  6. Steepest descent ballistic deposition of complex shaped particles

    Science.gov (United States)

    Topic, Nikola; Pöschel, Thorsten

    2016-03-01

    We present an efficient event-driven algorithm for sequential ballistic deposition of complex-shaped rigid particles. Each of the particles is constructed from hard spheres (typically 5 … 1000) of variable radii. The sizes and relative positions of the spheres may mutually overlap and can be chosen such that the surface of the resulting particle appears relatively smooth. In the sequential deposition process, by performing steps of rolling and linear motion, the particles move along the steepest descent in a landscape formed by the boundaries and previously deposited particles. The computer time for the simulation of a deposition process depends on the total number of spheres but only weakly on the sizes and shapes of the particles. The proposed algorithm generalizes the Visscher-Bolsterli algorithm [1] which is frequently used for packing of spheres, to non-spherical particles. The proposed event-driven algorithm allows simulations of multi-million particle systems using desktop computers.

  7. Crafting AIDS policy in Brazil and Russia: State-civil societal ties, institutionalised morals, and foreign policy aspiration.

    Science.gov (United States)

    Gómez, Eduardo J

    2016-10-01

    During the 1990s, Brazil and Russia diverged in their policy response to AIDS. This is puzzling considering that both nations were globally integrated emerging economies transitioning to democracy. This article examines to what extent international pressures and partnerships with multilateral donors motivated these governments to increase and sustain federal spending and policy reforms. Contrary to this literature, the cases of Brazil and Russia suggest that these external factors were not important in achieving these outcomes. Furthermore, it is argued that Brazil's policy response was eventually stronger than Russia's and that it had more to do with domestic political and social factors: specifically, AIDS officials' efforts to cultivate a strong partnership with NGOs, the absence of officials' moral discriminatory outlook towards the AIDS community, and the government's interest in using policy reform as a means to bolster its international reputation in health. PMID:27564438

  8. The Interaction of Language-Specific and Universal Factors During the Acquisition of Morphophonemic Alternations With Exceptions.

    Science.gov (United States)

    Baer-Henney, Dinah; Kügler, Frank; van de Vijver, Ruben

    2015-09-01

    Using the artificial language paradigm, we studied the acquisition of morphophonemic alternations with exceptions by 160 German adult learners. We tested the acquisition of two types of alternations in two regularity conditions while additionally varying length of training. In the first alternation, a vowel harmony, backness of the stem vowel determines backness of the suffix. This process is grounded in substance (phonetic motivation), and this universal phonetic factor bolsters learning a generalization. In the second alternation, tenseness of the stem vowel determines backness of the suffix vowel. This process is not based in substance, but it reflects a phonotactic property of German and our participants benefit from this language-specific factor. We found that learners use both cues, while substantive bias surfaces mainly in the most unstable situation. We show that language-specific and universal factors interact in learning.

  9. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    International Nuclear Information System (INIS)

    Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies

  10. Platelets in Lung Biology

    Science.gov (United States)

    Weyrich, Andrew S.; Zimmerman, Guy A.

    2013-01-01

    Platelets and the lungs have an intimate relationship. Platelets are anucleate mammalian blood cells that continuously circulate through pulmonary vessels and that have major effector activities in hemostasis and inflammation. The lungs are reservoirs for megakaryocytes, the requisite precursor cell in thrombopoiesis, which is the intricate process by which platelets are generated. Platelets contribute to basal barrier integrity of the alveolar capillaries, which selectively restricts the transfer of water, proteins, and red blood cells out of the vessels. Platelets also contribute to pulmonary vascular repair. Although platelets bolster hemostatic and inflammatory defense of the healthy lung, experimental evidence and clinical evidence indicate that these blood cells are effectors of injury in a variety of pulmonary disorders and syndromes. Newly discovered biological capacities of platelets are being explored in the context of lung defense, disease, and remodeling. PMID:23043249

  11. Science and Technology Review January/February 2011

    Energy Technology Data Exchange (ETDEWEB)

    Blobaum, K J

    2010-11-22

    This month's issue has the following articles: (1) World's Most Intense X-Ray Laser Focuses on Livermore Science - Commentary by William H. Goldstein; (2) Groundbreaking Science with the World's Brightest X Rays - Experiments with x rays of unparalleled brightness and extremely short duration aim to reveal new information about atoms and molecules in motion; (3) From Data to Discovery - Ongoing control system enhancements at the National Ignition Facility bolster the understanding of experimental data and keep the system performing at its peak; (4) The Sun in All Its Splendor - Onboard the Solar Dynamics Observatory, Livermore-developed multilayer mirrors are enabling unprecedented full-disk, high-resolution images of the Sun; and (5) Drilling Deep into Plant Veins - A novel combination of imaging techniques is being used to understand the three-dimensional architecture of plant cell walls.

  12. The evolution of index signals to avoid the cost of dishonesty.

    Science.gov (United States)

    Biernaskie, Jay M; Grafen, Alan; Perry, Jennifer C

    2014-09-01

    Animals often convey useful information, despite a conflict of interest between the signaller and receiver. There are two major explanations for such 'honest' signalling, particularly when the size or intensity of signals reliably indicates the underlying quality of the signaller. Costly signalling theory (including the handicap principle) predicts that dishonest signals are too costly to fake, whereas the index hypothesis predicts that dishonest signals cannot be faked. Recent evidence of a highly conserved causal link between individual quality and signal growth appears to bolster the index hypothesis. However, it is not clear that this also diminishes costly signalling theory, as is often suggested. Here, by incorporating a mechanism of signal growth into costly signalling theory, we show that index signals can actually be favoured owing to the cost of dishonesty. We conclude that costly signalling theory provides the ultimate, adaptive rationale for honest signalling, whereas the index hypothesis describes one proximate (and potentially very general) mechanism for achieving honesty. PMID:25056623

  13. Programming iOS 4 Fundamentals of iPhone, iPad, and iPod touch Development

    CERN Document Server

    Neuburg, Matt

    2011-01-01

    Get a solid grounding in all the fundamentals of Cocoa Touch, and avoid problems during iPhone and iPad app development. With Programming iOS 4, you'll dig into Cocoa and learn how to work effectively with Objective-C and Xcode. This book covers iOS 4 in a rigorous, orderly fashion-ideal whether you're approaching iOS for the first time or need a reference to bolster existing skills. Learn Objective-C language details and object-oriented programming conceptsUnderstand the anatomy of an Xcode project and all the stages of its lifecycleGrasp key Cocoa concepts such as relationships between clas

  14. Application of Proteomics and Lipid Studies in Environmental Biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Mukhopadhyay, Aindrila

    2008-08-12

    The overview of changes in protein levels or states in response to a growth condition, stress, mutation or metabolic engineering is invaluable in understanding the physiology of a microbial system. The lipid profile of the cell is similarly a valuable diagnostic of the cellular response and health, especially in context of survival in a fluctuating environment. To obtain comprehensive cellular models, post-transcriptional cell wide surveys at the levels of proteins and lipids are required. Both these fields have been greatly bolstered by the development of high throughput methods using mass spectrometry. Multiple strategies now exist for the identification of proteins, and numerous workflows to quantify protein abundance have also been developed. Cellular profiling such as these allows us to assess the potential of a microbial system for environmental applications such as bioremediation and bio-energy.

  15. MARKET WATCH

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The China Banking Regulatory Commission has kickstarted a pilot program to bolster consumer finance companies. This marks a step forward in the economic shift toward consumptions. In June, China trimmed a record net $25.1 billion in holdings from U.S. Treasury securities on concerns over the value of U.S. dollar assets. Air China Ltd., one of the country’s big three carriers, meanwhile, plans to raise its stake in Cathay Pacific Airways Ltd. to nearly 30 percent. China’s foreign direct investment inflows, at the same time, continued to decline in July, but its long-term prospects remain intact. The China Investment Corp. generated $23.1 billion in net profits last year and its return on registered capital was 6.8 percent.

  16. "To Bluff like a Man or Fold like a Girl?" - Gender Biased Deceptive Behavior in Online Poker.

    Science.gov (United States)

    Palomäki, Jussi; Yan, Jeff; Modic, David; Laakasuo, Michael

    2016-01-01

    Evolutionary psychology suggests that men are more likely than women to deceive to bolster their status and influence. Also gender perception influences deceptive behavior, which is linked to pervasive gender stereotypes: women are typically viewed as weaker and more gullible than men. We assessed bluffing in an online experiment (N = 502), where participants made decisions to bluff or not in simulated poker tasks against opponents represented by avatars. Participants bluffed on average 6% more frequently at poker tables with female-only avatars than at tables with male-only or gender mixed avatars-a highly significant effect in games involving repeated decisions. Nonetheless, participants did not believe the avatar genders affected their decisions. Males bluffed 13% more frequently than females. Unlike most economic games employed exclusively in research contexts, online poker is played for money by tens of millions of people worldwide. Thus, gender effects in bluffing have significant monetary consequences for poker players. PMID:27383472

  17. Claudia Quinta (Pro Caelio 34 and an altar to Magna Mater

    Directory of Open Access Journals (Sweden)

    Eleanor Winsor Leach

    2010-11-01

    Full Text Available Among the items of sculpture from the Capitoline collection now housed in the Museum of the Power Station Montemartini is a marble relief altar of the Claudian Period (E. Simon's dating dedicated to the mater deorum and the navis salvia and depicting the arrival of the goddess Cybele at Rome by ship. The dedicator is one Claudia Syntyche and the sculpture alludes to the legends attached to a much honored woman of the Claudian family whom Cicero, in his oration pro Caelio brought on stage in a cameo appearance to bolster his case against the controversial contemporary woman Clodia Metelli as one of the accusers of his client M. Caelius Rufus. This paper will consider questions raised by the iconography of the altar with reference to the development of Claudia's legend in Roman mythology and subsequently ask who was this Claudia the dedicator and why did she choose Magna Mater for her vow?

  18. Social media as social capital of LGB individuals in Hong Kong: its relations with group membership, stigma, and mental well-being.

    Science.gov (United States)

    Chong, Eddie S K; Zhang, Yin; Mak, Winnie W S; Pang, Ingrid H Y

    2015-03-01

    Social media are found to facilitate social information exchange among lesbian, gay, and bisexual (LGB) individuals who are subjected to social stigma. This study tested the protective role of LGB-tailored social media uses and gratifications in promoting LGB group membership, which we hypothesized to reduce LGB stigma and enhance mental health among LGB individuals in Hong Kong. Based on a sample of 233 Chinese LGB individuals in Hong Kong, structural equation modeling showed evidence for our hypotheses, χ(df=62)(2)= 88.20, GFI = 0.95, CFI = 0.98, NNFI = 0.98, SRMR = 0.07, RMSEA = 0.04. Community surveillance, identity expression, and emotional support on social media may promote mental health by instilling a sense of group membership and reducing stigma. Social media may build camaraderie and bolster resilience among LGB individuals that may otherwise be difficult in conservative regions.

  19. Evidence from the Special Relativity and Blackbody Radiation Theories for the Existence of Photons Possessing Zero Kinetic Energy

    CERN Document Server

    Buenker, R J

    1992-01-01

    The traditional interpretation of radiative emission and absorption asserts that photons are created and annihilated in such processes. A Gedanken experiment is considered in which kinetic energy from observed photons is systematically removed until a limit of zero is reached. With the help of the relativistic Doppler effect it is shown that even for infinitesimally small kinetic energies the photons continue to exist, since in other inertial systems they will be observed to have a much higher energy/frequency falling in an easily detectable range. It is possible to formulate an alternative explanation for absorption and emission processes on this basis in terms of real photons with exactly zero kinetic energy being present before or after radiative interactions. Bolstering this hypothesis is the fact that the statistical mechanical treatment of photons interacting with oscillators in blackbody radiation theory predicts an infinite density of photons of this energy, both in the original Planck formulation emp...

  20. Minimally invasive posterior hamstring harvest.

    Science.gov (United States)

    Wilson, Trent J; Lubowitz, James H

    2013-01-01

    Autogenous hamstring harvesting for knee ligament reconstruction is a well-established standard. Minimally invasive posterior hamstring harvest is a simple, efficient, reproducible technique for harvest of the semitendinosus or gracilis tendon or both medial hamstring tendons. A 2- to 3-cm longitudinal incision from the popliteal crease proximally, in line with the semitendinosus tendon, is sufficient. The deep fascia is bluntly penetrated, and the tendon or tendons are identified. Adhesions are dissected. Then, an open tendon stripper is used to release the tendon or tendons proximally; a closed, sharp tendon stripper is used to release the tendon or tendons from the pes. Layered, absorbable skin closure is performed, and the skin is covered with a skin sealant, bolster dressing, and plastic adhesive bandage for 2 weeks. PMID:24266003

  1. From Slash-and-burn to Disk Ploughing: The Land Policy and Tractors Behind Erosion and Forest Pioneer Farming in Southern Xayabury Province (Laos

    Directory of Open Access Journals (Sweden)

    Marc Dufumier

    2013-02-01

    Full Text Available Bordering Thailand, the southern part of Xayabury province is engaged in international trade and has experienced agricultural growth like nowhere else in Laos. The rapid transformation from manual slash-and-burn agriculture to mechanized, chemical-based cropping systems is often cited by Laotian authorities as a model of development. But a careful study of changes underway indicates that the reality is far less encouraging than it would appear at first. If many farmers have indeed bolstered their incomes over the last twenty years, it is no less true that some of the poorest peasants have become increasingly poorer and that the new techniques cause serious erosion, as they have not been able to prevent the expansion of cultivated areas on sloping lands.

  2. Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria?

    Science.gov (United States)

    Hemingway, Janet; Shretta, Rima; Wells, Timothy N C; Bell, David; Djimdé, Abdoulaye A; Achee, Nicole; Qi, Gao

    2016-03-01

    Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and prevent malaria, including innovative diagnostics, medicines, vaccines, vector control products, and improved mechanisms for surveillance and response. There are at least 25 projects in the global malaria vaccine pipeline, as well as 47 medicines and 13 vector control products. In addition, there are several next-generation diagnostic tools and reference methods currently in development, with many expected to be introduced in the next decade. The development and adoption of these tools, bolstered by strategies that ensure rapid uptake in target populations, intensified mechanisms for information management, surveillance, and response, and continued financial and political commitment are all essential to achieving global eradication.

  3. Clinical Experience in TCM Treatment of Insomnia

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Insomnia is a sleeping disorder that affects 1 in 10 Americans and around 50% of the seniors. It is often more prevalent in women. Since September 11, 2005 these estimations have increased. Insomnia can affect not only your energy level and mood, but your health as well because sleep helps bolster your immune system. Insomnia is characterized by: 1) difficulty in falling asleep; 2) waking up frequently during the night with difficulty of returning to sleep; 3) waking up too early in the morning; and 4) with unrefreshing sleep, the patient has a low spirit, palpation, poor memory, viscera function disorder. All these seriously affect the patient's life and work. The following is an account of the authors' clinical TCM experience in treating insomnia.

  4. Internet-based surveillance systems for monitoring emerging infectious diseases.

    Science.gov (United States)

    Milinovich, Gabriel J; Williams, Gail M; Clements, Archie C A; Hu, Wenbiao

    2014-02-01

    Emerging infectious diseases present a complex challenge to public health officials and governments; these challenges have been compounded by rapidly shifting patterns of human behaviour and globalisation. The increase in emerging infectious diseases has led to calls for new technologies and approaches for detection, tracking, reporting, and response. Internet-based surveillance systems offer a novel and developing means of monitoring conditions of public health concern, including emerging infectious diseases. We review studies that have exploited internet use and search trends to monitor two such diseases: influenza and dengue. Internet-based surveillance systems have good congruence with traditional surveillance approaches. Additionally, internet-based approaches are logistically and economically appealing. However, they do not have the capacity to replace traditional surveillance systems; they should not be viewed as an alternative, but rather an extension. Future research should focus on using data generated through internet-based surveillance and response systems to bolster the capacity of traditional surveillance systems for emerging infectious diseases.

  5. Commentary on Alcorn & Massé: troubling pedagogy

    Directory of Open Access Journals (Sweden)

    Michael O’Loughlin

    2011-12-01

    Full Text Available Responding to papers by Michelle Massé and Marshall Alcorn, I begin with an argument for the need to recognize ignorance as performative rather than merely as illustrative of student resistance in some pathological sense. I then explore the Lacanian notion that teachers develop imaginary suppositions about the lack in their students, and that these suppositions support rescue fantasies among teachers that are related to bolstering their own unconscious need for narcissistic gratification and love. I conclude by showing how these ideas resonate with my own autobiographical history as a teacher, as well as with key ideas in the two papers under discussion, and I commend both authors for opening up a valuable discussion of teaching as an “impossible profession”.

  6. From Awareness to Cultural Agency: EFL Colombian Student Teachers’ Travelling Abroad Experiences

    Directory of Open Access Journals (Sweden)

    John Jairo Viafara González

    2015-01-01

    Full Text Available Colombian English as a foreign language student teachers’ opportunities to grow as educators through international sojourns do not usually subsume the traditional study and residence abroad goal. This was the case for our participants who engaged mainly in working abroad with study being ancillary. Fifty student teachers from two public universities reported how their international sojourn bolstered their intercultural learning. Three different programs, disconnected from participants’ academic institutions, became vehicles for their experiences abroad. Surveys and interviews reveal that participants’ origin, selected programs, and contextual circumstances influenced their intercultural learning. As a result, intercultural development gravitated towards awareness of intercultural patterns, critical reading of culture, and pre-service teachers’ repositioning to build cultural agency. Implications suggest the need to connect traveling abroad programs to undergraduate curricula.

  7. Kinetic theory analysis of rarefied gas flow through finite length slots

    Science.gov (United States)

    Raghuraman, P.; Willis, D. R.

    1977-01-01

    A kinetic-theory analysis is made of the flow of a rarefied monatomic gas through a two-dimensional slot connecting two reservoirs. Numerical solutions are obtained by the moment and discrete-ordinate methods. The former method portrays the transition-regime characteristics well but has limitations in the free-molecule regime. The latter method gives accurate results in the free-molecule and slip regimes and bolsters confidence in the accuracy of the transition-regime results. The numerical solution for the mass flux through the slot agrees well with an approximate analytical solution of the moment equations for length-to-width ratios from 6 to 0.5, pressure ratios from 0.8 to 0.1, and Knudsen numbers from 5 to 0.5.

  8. The role of Vibrio cholerae genotyping in Africa.

    Science.gov (United States)

    De, Rituparna; Ghosh, Jayeeta Banerjee; Sen Gupta, Sourav; Takeda, Yoshifumi; Nair, G Balakrish

    2013-11-01

    Toxigenic Vibrio cholerae, the causative agent of the disease cholera, is prevalent in the African continent from the 1970s when the seventh pandemic spread from Asia to Africa. In the past decade, cholera has caused devastating outbreaks in much of Africa, illustrated by the recent cholera epidemics in Zimbabwe and regions of central Africa. Given the extent of cholera in Africa, a robust and efficient surveillance system should be in place to prevent and control the disease in this continent. Such a surveillance system would be greatly bolstered by use of molecular typing techniques to identify genetic subtypes. In this review, we highlight the role that modern molecular typing techniques can play in tracking and aborting the spread of cholera. PMID:24101642

  9. Analysis of Batik Value Chain in Ethnic Minority Areas--A Case Study of Danzhai County in Guizhou Province

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Based on value chain analysis method,we surveyed and interviewed interest groups of batik industry in Danzhai County.From raw material production,product processing,marketing,organization and management,we discussed the supply chain of batik products in ethnic minority areas,and analyzed favorable factors of batik industry development and obstacles to interest groups developing batik industry.Finally,we put forward corresponding policy suggestions,including strengthening farmers’ ability in batik production section,enhancing capability construction of batik cooperatives and associations,increasing cultural value added of batik products,bolster policy and financial support of government departments,and promoting establishment of cooperative mechanism for handicrafts.

  10. Psychical research and the origins of American psychology

    Science.gov (United States)

    Sommer, Andreas

    2012-01-01

    Largely unacknowledged by historians of the human sciences, late-19th-century psychical researchers were actively involved in the making of fledgling academic psychology. Moreover, with few exceptions historians have failed to discuss the wider implications of the fact that the founder of academic psychology in America, William James, considered himself a psychical researcher and sought to integrate the scientific study of mediumship, telepathy and other controversial topics into the nascent discipline. Analysing the celebrated exposure of the medium Eusapia Palladino by German-born Harvard psychologist Hugo Münsterberg as a representative example, this article discusses strategies employed by psychologists in the United States to expel psychical research from the agenda of scientific psychology. It is argued that the traditional historiography of psychical research, dominated by accounts deeply averse to its very subject matter, has been part of an ongoing form of ‘boundary-work’ to bolster the scientific status of psychology. PMID:23355763

  11. Gallinacin and Fowlicidin: Two Promising Antimicrobial Peptides in ChickensAND#8212;A Review

    Directory of Open Access Journals (Sweden)

    C. S. Mukhopadhyaya

    2010-12-01

    Full Text Available Antimicrobial peptides (AMP which have been identified in almost all groups of organisms, are the small cationic molecules that recognize the pathogen associated molecular patterns of the microbes. In chicken two main AMPs that play significant roles in bolstering the innate immunity are gallinacins and fowlicidins, which are the functional analogues of the mammalian beta-defensins and cathelicidins. Gallinacin identifies the Gram negative bacteria while fowlicidin exerts broad spectral activity. The basic mechanism of action is by far similar in both groups of AMPs. The ‘docking sites’ of these antimicrobial peptides includes the “lipid A” moiety of lipo polysaccharides, lipo-teichoic acids, anionic membrane phospholipids on bacterial surfaces. These AMPs block the DNA replication and protein synthesis in bacteria causing death of the microbe. Researchers have identified reproducible molecular markers of those peptides for selection of disease resistant stock of chickens. [Vet. World 2010; 3(6.000: 297-300

  12. Bounded agency in humanitarian settings: a qualitative study of adherence to antiretroviral therapy among refugees situated in Kenya and Malaysia.

    Science.gov (United States)

    Mendelsohn, Joshua B; Rhodes, Tim; Spiegel, Paul; Schilperoord, Marian; Burton, John Wagacha; Balasundaram, Susheela; Wong, Chunting; Ross, David A

    2014-11-01

    HIV-positive refugees confront a variety of challenges in accessing and adhering to antiretroviral therapy (ART) and attaining durable viral suppression; however, there is little understanding of what these challenges are, how they are navigated, or how they may differ across humanitarian settings. We sought to document and examine accounts of the threats, barriers and facilitators experienced in relation to HIV treatment and care and to conduct comparisons across settings. We conducted semi-structured interviews among a purposive sample of 14 refugees attending a public, urban HIV clinic in Kuala Lumpur, Malaysia (July-September 2010), and 12 refugees attending a camp-based HIV clinic in Kakuma, Kenya (February-March 2011). We used framework methods and between-case comparison to analyze and interpret the data, identifying social and environmental factors that influenced adherence. The multiple issues that threatened adherence to antiretroviral therapy or precipitated actual adherence lapses clustered into three themes: "migration", "insecurity", and "resilience". The migration theme included issues related to crossing borders and integrating into treatment systems upon arrival in a host country. Challenges related to crossing borders were reported in both settings, but threats pertaining to integration into, and navigation of, a new health system were exclusive to the Malaysian setting. The insecurity theme included food insecurity, which was most commonly reported in the Kenyan setting; health systems insecurity, reported in both settings; and emotional insecurity, which was most common in the Kenyan setting. Resilient processes were reported in both settings. We drew on the concept of "bounded agency" to argue that, despite evidence of personal and community resilience, these processes were sometimes insufficient for overcoming social and environmental barriers to adherence. In general, interventions might aim to bolster individuals' range of action with

  13. DYNAMICS OF FREIGHT CARS ON BOGIES MODEL 18-1711 WITH DIFFERENT WEDGE DE-SIGNS OF SPRING SUSPENSION

    Directory of Open Access Journals (Sweden)

    N. B. Mankevych

    2014-01-01

    Full Text Available Purpose. To analyze the results of the study of dynamic parameters of a gondola car, model 12-1704-04 with axle load 23.5 ton in bogies, models 18-1750 and two gondola cars, model 12-1905 with axial load of 25 ton, one of which is equipped with bogies, model 18-1711 with friction wedges of spring suspension with spatial form with increased angle to the horizontal line of intersection of the contact surfaces between the wedge and bolster, the other gondola car, model 12-1905 is equipped with bogies of the same model on which the friction wedges fitted with a flat form of contact surface. It has an angle of inclination like a wedge of bogie, model 18-100. On the basis of the obtained results to draw conclusions about the feasibility of unification design bogie bolster, model 18-1711 with bogie, model 18-100 by contact surfaces with elements of spring suspension. Methodology. Research on dynamic performance of cars was performed during running dynamic tests of specimens of freight cars in experimental train consisting of two locomotives, a laboratory, and three gondola cars of the above mentioned models. Findings. Main results of dynamic studies are presented as graphs of indicators on the speed of the train and the experimental evidence that the freight gondola cars on bogies, model 18-1711 with flat-shaped wedges, in most cases are better than the others. Originality. Research results of cars on bogies, model 18-1711 were obtained. They let assess the dependence of the dynamic performance of the car from the design of the friction wedges of spring suspension. Practical value. Cast parts of bogie, model 18-1711 with 25 ton axle load can be used as a replacement of defective parts of bogie, model 18-100 and its analogs.

  14. Bounded agency in humanitarian settings: a qualitative study of adherence to antiretroviral therapy among refugees situated in Kenya and Malaysia.

    Science.gov (United States)

    Mendelsohn, Joshua B; Rhodes, Tim; Spiegel, Paul; Schilperoord, Marian; Burton, John Wagacha; Balasundaram, Susheela; Wong, Chunting; Ross, David A

    2014-11-01

    HIV-positive refugees confront a variety of challenges in accessing and adhering to antiretroviral therapy (ART) and attaining durable viral suppression; however, there is little understanding of what these challenges are, how they are navigated, or how they may differ across humanitarian settings. We sought to document and examine accounts of the threats, barriers and facilitators experienced in relation to HIV treatment and care and to conduct comparisons across settings. We conducted semi-structured interviews among a purposive sample of 14 refugees attending a public, urban HIV clinic in Kuala Lumpur, Malaysia (July-September 2010), and 12 refugees attending a camp-based HIV clinic in Kakuma, Kenya (February-March 2011). We used framework methods and between-case comparison to analyze and interpret the data, identifying social and environmental factors that influenced adherence. The multiple issues that threatened adherence to antiretroviral therapy or precipitated actual adherence lapses clustered into three themes: "migration", "insecurity", and "resilience". The migration theme included issues related to crossing borders and integrating into treatment systems upon arrival in a host country. Challenges related to crossing borders were reported in both settings, but threats pertaining to integration into, and navigation of, a new health system were exclusive to the Malaysian setting. The insecurity theme included food insecurity, which was most commonly reported in the Kenyan setting; health systems insecurity, reported in both settings; and emotional insecurity, which was most common in the Kenyan setting. Resilient processes were reported in both settings. We drew on the concept of "bounded agency" to argue that, despite evidence of personal and community resilience, these processes were sometimes insufficient for overcoming social and environmental barriers to adherence. In general, interventions might aim to bolster individuals' range of action with

  15. The Australian Hydrogen and Fuel Cells Education Program

    International Nuclear Information System (INIS)

    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  16. The Australian Hydrogen and Fuel Cells Education Program

    Energy Technology Data Exchange (ETDEWEB)

    Luigi Bonadio [Senior Consultant Luigi Bonadio and Associates (Australia)

    2006-07-01

    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  17. Upper lid crease approach for margin rotation in trachomatous cicatricial entropion without external sutures

    Directory of Open Access Journals (Sweden)

    Antonio Augusto Velasco e Cruz

    2015-12-01

    Full Text Available ABSTRACT Purpose: To describe the use of a lid crease incision for upper eyelid margin rotation in cicatricial entropion combining internal traction on the anterior lamella, tarsotomy, and tarsal overlap without external sutures. Methods: Surgical description: The main steps of the procedure consisted of exposure of the entire tarsal plate up to the eyelashes followed by tarsotomy through the conjunctiva. A double-armed 6.0 polyglactin suture was then passed through the distal tarsal fragment to the marginal section of the orbicularis oculi muscle. As the sutures were tied, the distal tarsus advanced over the marginal section, and traction was exerted on the marginal strip of the orbicularis muscle. There were no bolsters or external knots. The pretarsal skin-muscle flap was closed with a 6.0 plain gut suture. Results: We used this procedure at a tertiary hospital in Saudi Arabia from 2013 to 2014. Sixty upper lids of 40 patients (23 women and 17 men were operated on, with an age range of 44-99 years [mean ± standard deviation (SD = 70.9 ± 13.01 years]. Bilateral surgery was performed on 21 patients. Follow-up ranged from 1 to 12 months (mean 3.0 ± 2.71 months. Forty percent of the patients (24 lids had more than 3 months' follow-up. The postoperative lid margin position was good in all cases. Trichiasis (two lashes was observed in only one patient with unilateral entropion on the medial aspect of the operated lid. Conclusions: The upper lid margin can be effectively rotated through a lid crease incision with internal sutures. The technique combines the main mechanisms of the Wies and Trabut approaches and avoids the use of bolsters or external sutures, which require a second consultation to be removed. Some other lid problems, such as ptosis, retraction, or dermatochalasis, can be concomitantly addressed during the procedure.

  18. Fiscal and Macroeconomic Effects of Colombia`s Pension Reform Fiscal and Macroeconomic Effects of Colombia`s Pension Reform

    Directory of Open Access Journals (Sweden)

    Klaus Schmidt-Hebbel

    1997-03-01

    Full Text Available In 1994 Colombia started replacing its state-run and pay-as-you-go (PAYG pension system by a privately-run and fully-funded scheme. Numerical simulations for the government's reform transition reveal implicit PAYG debt levels and corresponding reform transition deficits that are high relative to other countries, considering that Colombia's old pension system was characterized by low coverage, low system maturity, and a young population.Simulation results show that output could increase by 10% due to higher future saving caused by financing the pension deficit by a fiscal contraction -but this would occur only in the very long term. Sooner and possibly larger gains could be reaped from higher employment and production in formal sectors, and the development of capital markets spurred by the reform. In addition, Colombia's new pension systemthat includes a redistributive pillar targeted at the poor -is potentially more equitable than the old scheme, To reap these efficiency and equity bellefits, however, the Colombian government would have to adopt complementary reforms. They include giving the private fully-funded pension pillar a commanding role, supporting the development of capital markets, and bolstering formal-sector employment by the reduction of deadweight tax burden of non-pension programs that are currently financed by payroll taxes on labor. In 1994 Colombia started replacing its state-run and pay-as-you-go (PAYG pension system by a privately-run and fully-funded scheme. Numerical simulations for the government's reform transition reveal implicit PAYG debt levels and corresponding reform transition deficits that are high relative to other countries, considering that Colombia's old pension system was characterized by low coverage, low system maturity, and a young population.Simulation results show that output could increase by 10% due to higher future saving caused by financing the pension deficit by a fiscal contraction -but this would

  19. 基于美国ASME标准的重载货车车体焊缝疲劳寿命预测%Fatigue life prediction for weld line in heavy freight carbody based on ASME standard

    Institute of Scientific and Technical Information of China (English)

    谢素明; 周晓坤; 李向伟; 李晓峰

    2012-01-01

    为寻求在设计阶段能较准确地预测重载货车车体焊缝的疲劳寿命评估方法,基于各种标准提供的分析方法对转炉616装甲钢T型焊接接头进行疲劳评估,通过与试验的对比表明,美国ASME标准中的等效结构应力法更能准确预测焊缝的疲劳寿命。为提高某重载运煤敞车车体焊缝的疲劳寿命,建立了包括焊缝在内的敞车车体有限元模型,基于等效结构应力法和AAR标准中的载荷谱,预测了车体关键焊缝的疲劳寿命,其薄弱部位与车体实际发生疲劳裂纹部位基本吻合,依据焊缝的结构应力分布规律的特点,提出的枕梁改进结构可使车体关键焊缝疲劳寿命提高1.7倍。%Aiming at finding a more exact method to predict weld line fatigue life in heavy freight carbody during design phase, the fatigue life of armor steel 616 Tee joint is analyzed by various standards. Comparing analysis results and experimental results,the equivalent structural stress method offered by ASME standard is of high accuracy and obvious advantage. A finite element model of a heavy freight carbody including key weld lines is built, fatigue life prediction for these weld lines is performed by means of the equivalent structural stress method and load spectrum of AAR,and weld line of more shorter fatigue life is basically coincident with that in-service carbody. The improved structure of bolsters is to be put forward on the basis of structural stress analysis at weld lines, and fatigue life of the bolsters weld line is increased by 1.7 times.

  20. National intelligence, suicide rate in the elderly, and a threshold intelligence for suicidality: an ecological study of 48 Eurasian countries.

    Science.gov (United States)

    Voracek, Martin

    2005-11-01

    Across 85 countries around the world, Voracek (2004) found a significant positive relation between estimated national intelligence (IQ) and national male and female suicide rate. The relation was not attenuated when countries' per capita Gross Domestic Product (GDP) and type of national IQ estimation were statistically controlled. Independently, investigating the total national suicide rate only, Lester (2003) arrived at the same conclusion. These two findings are consistent with a corollary of de Catanzaro's (1981) evolutionary theory of human suicide, namely that a threshold intelligence is necessary for suicidality and that intelligence and suicide mortality should thus be positively related. Here, further evidence for this hypothesis is bolstered by focusing on suicide rates of the elderly. Across 48 Eurasian countries, estimated national IQ was significantly positively related to national suicide rates of people aged 65 years and over. This new ecological-level finding survived statistical controlling for a set of seven variables (type of national IQ estimation, national GDP, stableness and recency measures for suicide rates, and rates of adult literacy, urbanization and Roman Catholics), which thus are not confounding factors for the relation of intelligence and suicide mortality. Based on ecological data, the threshold IQ for suicidality is predicted to be 70 or slightly over, an estimate that is consistent with various suicidological observations. PMID:16221322

  1. Sex differences in preferences for humor: a replication, modification, and extension.

    Science.gov (United States)

    Hone, Liana S E; Hurwitz, William; Lieberman, Debra

    2015-01-01

    Evolutionary-minded scientists have proposed that humor is a sexually selected trait in men that signals mate quality. Indeed, women tend to prefer men who make them laugh and men tend to prefer women who laugh at their jokes. However, it is unclear how robust this pattern is. Here we report a replication of one of the first studies (Bressler, Martin, and Balshine, 2006) to examine the sex differences in preferences for humor receptivity versus humor production. We replicate Bressler et al.'s (2006) findings that men prefer women who are receptive to their humor whereas women prefer men who produce humor. These findings held even after we modified Bressler et al.'s questionnaire for better conceptual validity. Furthermore, using a separate measure designed to assess trade-offs, we found that men viewed humor receptivity as a necessity and humor production as a luxury when they were asked to create an ideal long-term partner. For women, it was just the opposite. These results bolster the claim that sexual selection has shaped sex differences regarding preferences for a prospective mate's sense of humor and that what one means by "sense of humor" can vary. PMID:25670631

  2. Smart Growth and the Challenge of Nimby: Multifamily Dwellings and their Association with Single-Family House Selling Prices in Tallahasse, Florida, USA

    Directory of Open Access Journals (Sweden)

    Huston GIBSON

    2013-06-01

    Full Text Available Citizens protest development when they consider it undesirable. One type of development commonly perceived as undesirable by single-family home owners is proximate multifamily housing, often considered a cause of property devaluation. This study assesses multifamily housing, by typology, and its monetary association with proximate single-family housing prices. The research design is a cross-sectional study using multivariate regression. The unit of analysis is the detached single-family dwelling. The study population is a sample taken from all arms-length owner-occupied, primary residence, detached single-family property transactions recorded in Tallahassee-Leon County, Florida, USA, during 2008. The key findings show no statistically significant negative associations between multifamily housing and single-family property selling prices in the sample; in fact, the two were positively correlated. These findings address single-family homeowner concerns about proximate multifamily housing and should bolster the political feasibility of Smart Growth policy, which recommends denser urban infill.

  3. Preparing our Workforce (POW) Initiative: Utilizing Moodle to Prepare Students for the Geoscience Workforce

    Science.gov (United States)

    Houlton, H. R.; Keane, C. M.; Wilson, C. E.

    2013-12-01

    Bridging the workforce supply gap is an increasing concern among the geoscience community as our current geoscience professionals approach retirement age. To ensure the sustainability of our future workforce, the American Geosciences Institute (AGI) developed a program called the Preparing our Workforce (POW) Initiative to discuss the diverse career opportunities with geoscience students. These discussion-based, student-led talks bring together geoscience students and working professionals that emphasize the importance of integrating transferrable skills and outside interests to bolster one's career. Through the Geoscience Online Learning Initiative, (GOLI) sponsored by AGI and the American Institute of Professional Geologists (AIPG), nation-wide implementation is currently underway by employing Moodle to train geoscience professionals to host POW discussions with students in their area. The POW course currently utilizes many of Moodle's features including video streaming, discussion forums, assessments, databases and restricted access to materials. This talk will address the innovative structure, goals and implementation of the POW Initiative. Additionally, it will discuss future courses in Moodle that will address workforce needs and how to become more formally involved in the POW Initiative.

  4. Pharmacological Properties and Therapeutic Potential of Naringenin: A Citrus Flavonoid of Pharmaceutical Promise.

    Science.gov (United States)

    Rani, Neha; Bharti, Saurabh; Krishnamurthy, Bhaskar; Bhatia, Jagriti; Sharma, Charu; Kamal, Mohammad Amjad; Ojha, Shreesh; Arya, Dharamvir Singh

    2016-01-01

    Naringenin chemically known as 5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one is a common dietary polyphenolic constituent of the citrus fruits. It has received considerable attention for pharmaceutical and nutritional development due to potent pharmacological activities and therapeutic potential. Accruing evidence from both in vitro and in vivo studies have unraveled numerous biological targets along with complex underlying mechanisms suggesting possible therapeutic applications of naringenin in various neurological, cardiovascular, gastrointestinal, rheumatological, metabolic and malignant disorders. Functionally, this ameliorative effect of naringenin is primarily attributed to its antiinflammatory (via inhibiting recruitment of cytokines and inflammatory transcription factors) and anti-oxidant (via scavenging of free radicals, bolstering of endogenous antioxidant defense system and metal ion chelation) effects. The present article provides a comprehensive review of the various studies that have evaluated the therapeutic potential of naringenin and its actions at the molecular level. It also summarizes the pharmacokinetic data and issues and challenges involved in pharmaceutical development and suggest that it may be a potential agent for further exploration as well as may be useful as a dietary adjunct in treatment of various human ailments. PMID:27238365

  5. The Julius Rosenwald Fund syphilis seroprevalence studies.

    Science.gov (United States)

    Roy, B

    1996-05-01

    In 1929 the Julius Rosenwald Fund, in conjunction with the Public Health Service (PHS), sponsored a syphilis seroprevalence study in the South characterized as a humanitarian effort to benefit the health of rural African Americans. The study reported extraordinarily high rates of positive Wassermann tests, even among children. Despite the unreliability and nonspecificity of this test, modern authors continue to indict these subjects as syphilitic. However, there was no consistent relationship between syphilis and a positive Wassermann test. Additional treponemal pathogens that potentially caused false-positive tests could explain the results. After public outcry to the Tuskegee Syphilis Experiment, the Rosenwald study acquired new significance. It was used as evidence to bolster the argument that Tuskegee was a consequence of humanitarian motives that became captive to misguided methods of researchers at the Venereal Disease Division of the PHS. Humanitarianism implies the acknowledgement of a right invested in the recipient; health is an end in itself. However, African Americans were necessary as a source of cheap labor for competition in the world cotton markets and as a restraint on the market value of white labor in manufacturing. The administrative structure of the PHS, not zealous individuals, adopted utilitarianism as its paradigm for human research. Syphilis seroprevalence was a calculated use of public health as a means to economic development. PMID:8667443

  6. A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease.

    Science.gov (United States)

    Barry, Meagan A; Wang, Qian; Jones, Kathryn M; Heffernan, Michael J; Buhaya, Munir H; Beaumier, Coreen M; Keegan, Brian P; Zhan, Bin; Dumonteil, Eric; Bottazzi, Maria Elena; Hotez, Peter J

    2016-04-01

    Chagas disease, caused by Trypanosoma cruzi, results in an acute febrile illness that progresses to chronic chagasic cardiomyopathy in 30% of patients. Current treatments have significant side effects and poor efficacy during the chronic phase; therefore, there is an urgent need for new treatment modalities. A robust TH1-mediated immune response correlates with favorable clinical outcomes. A therapeutic vaccine administered to infected individuals could bolster the immune response, thereby slowing or stopping the progression of chagasic cardiomyopathy. Prior work in mice has identified an efficacious T. cruzi DNA vaccine encoding Tc24. To elicit a similar protective cell-mediated immune response to a Tc24 recombinant protein, we utilized a poly(lactic-co-glycolic acid) nanoparticle delivery system in conjunction with CpG motif-containing oligodeoxynucleotides as an immunomodulatory adjuvant. In a BALB/c mouse model, the vaccine produced a TH1-biased immune response, as demonstrated by a significant increase in antigen-specific IFNγ-producing splenocytes, IgG2a titers, and proliferative capacity of CD8(+) T cells. When tested for therapeutic efficacy, significantly reduced systemic parasitemia was seen during peak parasitemia. Additionally, there was a significant reduction in cardiac parasite burden and inflammatory cell infiltrate. This is the first study demonstrating immunogenicity and efficacy of a therapeutic Chagas vaccine using a nanoparticle delivery system. PMID:26890466

  7. Management for Mountain Pine Beetle Outbreak Suppression: Does Relevant Science Support Current Policy?

    Directory of Open Access Journals (Sweden)

    Diana L. Six

    2014-01-01

    Full Text Available While the use of timber harvests is generally accepted as an effective approach to controlling bark beetles during outbreaks, in reality there has been a dearth of monitoring to assess outcomes, and failures are often not reported. Additionally, few studies have focused on how these treatments affect forest structure and function over the long term, or our forests’ ability to adapt to climate change. Despite this, there is a widespread belief in the policy arena that timber harvesting is an effective and necessary tool to address beetle infestations. That belief has led to numerous proposals for, and enactment of, significant changes in federal environmental laws to encourage more timber harvests for beetle control. In this review, we use mountain pine beetle as an exemplar to critically evaluate the state of science behind the use of timber harvest treatments for bark beetle suppression during outbreaks. It is our hope that this review will stimulate research to fill important gaps and to help guide the development of policy and management firmly based in science, and thus, more likely to aid in forest conservation, reduce financial waste, and bolster public trust in public agency decision-making and practice.

  8. Noninvasive low-level laser therapy for thrombocytopenia.

    Science.gov (United States)

    Zhang, Qi; Dong, Tingting; Li, Peiyu; Wu, Mei X

    2016-07-27

    Thrombocytopenia is a common hematologic disorder that is managed primarily by platelet transfusions. We report here that noninvasive whole-body illumination with a special near-infrared laser cures acute thrombocytopenia triggered by γ-irradiation within 2 weeks in mice, as opposed to a 5-week recovery time required in controls. The low-level laser (LLL) also greatly accelerated platelet regeneration in the presence of anti-CD41 antibody that binds and depletes platelets, and prevented a severe drop in platelet count caused by a common chemotherapeutic drug. Mechanistically, LLL stimulated mitochondrial biogenesis specifically in megakaryocytes owing to polyploidy of the cells. LLL also protected megakaryocytes from mitochondrial injury and apoptosis under stress. The multifaceted effects of LLL on mitochondria bolstered megakaryocyte maturation; facilitated elongation, branching, and formation of proplatelets; and doubled the number of platelets generated from individual megakaryocytes in mice. LLL-mediated platelet biogenesis depended on megakaryopoiesis and was inversely correlated with platelet counts, which kept platelet biogenesis in check and effectively averted thrombosis even after repeated uses, in sharp contrast to all current agents that stimulate the differentiation of megakaryocyte progenitors from hematopoietic stem cells independently of platelet counts. This safe, drug-free, donor-independent modality represents a paradigm shift in the prophylaxis and treatment of thrombocytopenia. PMID:27464749

  9. Influence of MnO2 decorated Fe nano cauliflowers on microwave absorption and impedance matching of polyvinylbutyral (PVB) matrix

    Science.gov (United States)

    Bora, Pritom J.; Porwal, Mayuri; Vinoy, K. J.; Ramamurthy, Praveen C.; Madras, Giridhar

    2016-09-01

    In this work, a promising, polyvinyl butryl (PVB)-MnO2 decorated Fe composite was synthesised and microwave absorption properties were studied for the most important frequency ranges i.e., X-band (8.2–12.4 GHz) and Ku-band (12.4–18 GHz). The microwave absorption of Fe nano cauliflower structure can be enhanced by MnO2 nanofiber coating. 10 wt% Fe–MnO2 nano cauliflower loaded PVB composite films (2 mm thick) shows an appreciable increase in microwave absorption properties. In X-band, the reflection loss (RL) of this composite decreases almost linearly to ‑7.5 dB, whereas in the Ku-band the minimum RL was found to be ‑15.7 dB at 14.7 GHz. Here it was observed that impedance matching is the primarily important factor responsible for enhanced microwave absorption. Further, enhancement of EM attenuation constant (α), dielectrics, scattering attenuation also bolsters the obtained results. This polymer composite can be considered as a novel microwave absorbing coating material.

  10. Coherent state description of non-topological solitons and momentum projection

    International Nuclear Information System (INIS)

    The solitons we are studing are localized, static solutions to classical (or semiclassical) non-linear field equations. Being localized, they do not correspond to momentum eigenstates, even though the field theories we are trying to solve are translationally invariant. In order to construct states of good momentum we need an explicity quantum wave function and not just expectation values of the fields (which are all we can get from a semiclassical treatment). The techniques discussed provide a wave function which embodies many of the features of the semiclassical (or mean field) approximation. This wave function can be projected onto states of definite momentum and hence can be used to calculate center-of-mass corrections to soliton properties. Many of the ideas involved have been around since the early days of quantum field theory but they have received little application apart from work by Bolsterli and Parmentola. The specific model to which we apply these methods is the soliton bag model of Friedberg and Lee. This is a model for the low energy properties of QCD in which hadrons appear as solitons in a scalar field with quarks trapped inside them. 27 references

  11. Treatment and recycling of spent nuclear fuel. Actinide partitioning - Application to waste management

    International Nuclear Information System (INIS)

    subsequent to its in-reactor dwell time, spent fuel still contains large amounts of materials that are recoverable, for value-added energy purposes (uranium, plutonium), together with fission products, and minor actinides, making up the residues from nuclear reactions. The treatment and recycling of spent nuclear fuel, as implemented in France, entail that such materials be chemically partitioned. The development of the process involved, and its deployment on an industrial scale stand as a high achievement of French science, and technology. Treatment and recycling allow both a satisfactory management of nuclear waste to be implemented, and substantial savings, in terms of fissile material. Bolstered of late as it has been, due to spectacularly skyrocketing uranium prices, this strategy is bound to become indispensable, with the advent of the next generation of fast reactors. This Monograph surveys the chemical process used for spent fuel treatment, and its variants, both current, and future. It outlines currently ongoing investigations, setting out the challenges involved, and recent results obtained by CEA. (authors)

  12. Treatment and recycling of spent nuclear fuel. Actinide partitioning - Application to waste management

    Energy Technology Data Exchange (ETDEWEB)

    Abonneau, E.; Baron, P.; Berthon, C.; Berthon, L.; Beziat, A.; Bisel, I.; Bonin, L.; Bosse, E.; Boullis, B.; Broudic, J.C.; Charbonnel, M.C.; Chauvin, N.; Den Auwer, C.; Dinh, B.; Duhamet, J.; Escleine, J.M.; Grandjean, S.; Guilbaud, P.; Guillaneux, D.; Guillaumont, D.; Hill, C.; Lacquement, J.; Masson, M.; Miguirditchian, M.; Moisy, P.; Pelletier, M.; Ravenet, A.; Rostaing, C.; Royet, V.; Ruas, A.; Simoni, E.; Sorel, C.; Vaudano, A.; Venault, L.; Warin, D.; Zaetta, A.; Pradel, P.; Bonin, B.; Bouquin, B.; Dozol, M.; Lecomte, M.; Forestier, A.; Beauvy, M.; Berthoud, G.; Defranceschi, M.; Ducros, G.; Guerin, Y.; Latge, C.; Limoge, Y.; Madic, C.; Santarini, G.; Seiler, J.M.; Sollogoob, P.; Vernaz, E.; Bazile, F.; Parisot, J.P.; Finot, P.; Roberts, J.F

    2008-07-01

    subsequent to its in-reactor dwell time, spent fuel still contains large amounts of materials that are recoverable, for value-added energy purposes (uranium, plutonium), together with fission products, and minor actinides, making up the residues from nuclear reactions. The treatment and recycling of spent nuclear fuel, as implemented in France, entail that such materials be chemically partitioned. The development of the process involved, and its deployment on an industrial scale stand as a high achievement of French science, and technology. Treatment and recycling allow both a satisfactory management of nuclear waste to be implemented, and substantial savings, in terms of fissile material. Bolstered of late as it has been, due to spectacularly skyrocketing uranium prices, this strategy is bound to become indispensable, with the advent of the next generation of fast reactors. This Monograph surveys the chemical process used for spent fuel treatment, and its variants, both current, and future. It outlines currently ongoing investigations, setting out the challenges involved, and recent results obtained by CEA. (authors)

  13. Exploratory study of the feasibility and utility of the colored eco-genetic relationship map (CEGRM) in women at high genetic risk of developing breast cancer.

    Science.gov (United States)

    Peters, June A; Kenen, Regina; Giusti, Ruthann; Loud, Jennifer; Weissman, Nancy; Greene, Mark H

    2004-10-15

    We report here the results of an exploratory feasibility study of the colored eco-genetic relationship map (CEGRM), a novel, recently-developed psychosocial assessment tool, which incorporates features of the genetic pedigree, family systems genogram, and ecomap. The CEGRM presents a simple, concise, visual representation of the social interaction domains of information, services, and emotional support through the application of color-coded symbols to the genetic pedigree. The interactive process of completing the CEGRM was designed to facilitate contemporary genetic counseling goals of: (a) understanding the client in the context of her/his social milieu; (b) bolstering client self-awareness and insight; (c) fostering active client participation and mutuality in the counseling interaction; (d) eliciting illuminating social narratives; and (e) addressing outstanding emotional issues. Twenty women participating in a breast imaging study of women from families with BRCA1/2 mutations completed and evaluated various aspects of the CEGRM. We found that efficient construction of the CEGRM was feasible, and that compliance was excellent. Participants developed insights into their social milieu through observing the visual pattern of relationships illustrated by the CEGRM. The process of co-constructing the CEGRM fostered the participant's active involvement in the session, marked by mutuality and increased empathy. In this clinical research context, the participants felt free to share poignant stories about their friends and families. Further studies are planned to refine the CEGRM and to examine its utility in cancer genetics research. PMID:15378540

  14. A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid.

    Science.gov (United States)

    Whitlock, Jarred M; Hartzell, H Criss

    2016-03-01

    Since their first descriptions, ion channels have been conceived as proteinaceous conduits that facilitate the passage of ionic cargo between segregated environments. This concept is reinforced by crystallographic structures of cation channels depicting ion conductance pathways completely lined by protein. Although lipids are sometimes present in fenestrations near the pore or may be involved in channel gating, there is little or no evidence that lipids inhabit the ion conduction pathway. Indeed, the presence of lipid acyl chains in the conductance pathway would curse the design of the channel's aqueous pore. Here, we make a speculative proposal that anion channels in the TMEM16/ANO superfamily have ion conductance pathways composed partly of lipids. Our reasoning is based on the idea that TMEM16 ion channels evolved from a kind of lipid transporter that scrambles lipids between leaflets of the membrane bilayer and the modeled structural similarity between TMEM16 lipid scramblases and TMEM16 anion channels. This novel view of the TMEM16 pore offers explanation for the biophysical and pharmacological oddness of TMEM16A. We build upon the recent X-ray structure of nhTMEM16 and develop models of both TMEM16 ion channels and lipid scramblases to bolster our proposal. It is our hope that this model of the TMEM16 pore will foster innovative investigation into TMEM16 function.

  15. A Revised Method of Presenting Wavenumber-Frequency Power Spectrum Diagrams That Reveals the Asymmetric Nature of Tropical Large-scale Waves

    Science.gov (United States)

    Chao, Winston C.; Yang, Bo; Fu, Xiouhua

    2007-01-01

    The popular method of presenting wavenumber-frequency power spectrum diagrams for studying tropical large-scale waves in the literature is shown to give an incomplete presentation of these waves. The so-called "convectively-coupled Kelvin (mixed Rossby-gravity) waves" are presented as existing only in the symmetric (antisymmetric) component of the diagrams. This is obviously not consistent with the published composite/regression studies of "convectively-coupled Kelvin waves," which illustrate the asymmetric nature of these waves. The cause of this inconsistency is revealed in this note and a revised method of presenting the power spectrum diagrams is proposed. When this revised method is used, "convectively-coupled Kelvin waves" do show anti-symmetric components, and "convectively-coupled mixed Rossby-gravity waves (also known as Yanai waves)" do show a hint of symmetric components. These results bolster a published proposal that these waves be called "chimeric Kelvin waves," "chimeric mixed Rossby-gravity waves," etc. This revised method of presenting power spectrum diagrams offers a more rigorous means of comparing the General Circulation Models (GCM) output with observations by calling attention to the capability of GCMs in correctly simulating the asymmetric characteristics of the equatorial waves.

  16. Human embryonic stem cell therapies for neurodegenerative diseases.

    Science.gov (United States)

    Tomaskovic-Crook, Eva; Crook, Jeremy M

    2011-06-01

    There is a renewed enthusiasm for the clinical translation of human embryonic stem (hES) cells. This is abetted by putative clinically-compliant strategies for hES cell maintenance and directed differentiation, greater understanding of and accessibility to cells through formal cell registries and centralized cell banking for distribution, the revised US government policy on funding hES cell research, and paradoxically the discovery of induced pluripotent stem (iPS) cells. Additionally, as we consider the constraints (practical and fiscal) of delivering cell therapies for global healthcare, the more efficient and economical application of allogeneic vs autologous treatments will bolster the clinical entry of hES cell derivatives. Neurodegenerative disorders such as Parkinson's disease are primary candidates for hES cell therapy, although there are significant hurdles to be overcome. The present review considers key advances and challenges to translating hES cells into novel therapies for neurodegenerative diseases, with special consideration given to Parkinson's disease and Alzheimer's disease. Importantly, despite the focus on degenerative brain disorders and hES cells, many of the issues canvassed by this review are relevant to systemic application of hES cells and other pluripotent stem cells such as iPS cells.

  17. Jordanian Preservice Primary Teachers' Perceptions of Mentoring in Science Teaching

    Science.gov (United States)

    Abed, Osama H.; Abd-El-Khalick, Fouad

    2015-03-01

    Quality mentoring is fundamental to preservice teacher education because of its potential to help student and novice teachers develop the academic and pedagogical knowledge and skills germane to successful induction into the profession. This study focused on Jordanian preservice primary teachers' perceptions of their mentoring experiences as these pertain to science teaching. The Mentoring for Effective Primary Science Teaching instrument was administered to 147 senior preservice primary teachers in a university in Jordan. The results indicated that the greater majority of participants did not experience effective mentoring toward creating a supportive and reflexive environment that would bolster their confidence in teaching science; further their understanding of primary science curriculum, and associated aims and school policies; help with developing their pedagogical knowledge; and/or furnish them with specific and targeted feedback and guidance to help improve their science teaching. Substantially more participants indicated that their mentors modeled what they perceived to be effective science teaching. The study argues for the need for science-specific mentoring for preservice primary teachers, and suggests a possible pathway for achieving such a model starting with those in-service primary teachers-much like those identified by participants in the present study-who are already effective in their science teaching.

  18. From road to lab to math: the co-evolution of technological, regulatory, and organizational innovations for automotive crash testing.

    Science.gov (United States)

    Leonardi, Paul M

    2010-04-01

    Today, in the midst of economic crisis, senior executives at US automakers and influential industry analysts frequently reflect on the progression that safety testing has taken from the crude trials done on the road, to controlled laboratory experiments, and to today's complex math-based simulation models. They use stories of this seemingly linear and natural sequence to justify further investment in simulation technologies. The analysis presented in this paper shows that change in the structures of automakers' organizations co-evolved with regulations specifying who was at fault in vehicle impacts, how vehicles should be built to withstand the force of an impact, and how testing should be done to assure that vehicles met those requirements. Changes in the regulatory environment were bolstered by new theories about crash test dynamics and changing technologies with which to test those theories. Thus, as new technological and regulatory innovations co-evolved with innovations in organizational structuring, ideas about how to best conduct crash tests shifted and catalyzed new cycles of technological, regulatory, and organizational innovation. However, this co-evolutionary story tells us that the move from road to lab to math was not natural or linear as today's managerial rhetoric would have us believe. Rather, the logic of math-based simulation was the result of technological, regulatory and organizational changes that created an industry-wide ideology that supported the move toward math while making it appear natural within the shifting structure of the industry.

  19. The Contribution of and Uncertainty Associated with Self-Multiplication when Assaying Plutonium in Waste by Passive Neutron Coincidence Counting

    International Nuclear Information System (INIS)

    When Pu is present in waste items as lumps, the Reals neutron coincidence signal may be bolstered by virtue of self induced fission events. This gives rise to a positive bias to the assay result and leads to a one sided contribution to the total measurement uncertainty. In the general it is not feasible to determine to magnitude of this effect experimentally and allowance for it must therefore be estimated using separate ad hoc rules. In this paper we to develop a simple model for the self-multiplication enhancement in small lumps allowing the importance of the effect in waste assay to be quantified. In addition, an approach is suggested for how to propagate an uncertainty contribution in to the final result. In conclusion: By introducing a generic scheme we have taken the first pragmatic steps to accounting for multiplication effects in the TMU in the determination of Pu-240 eff-mass by PNCC in waste. We have used a simple physical model to derive the underlying relationships needed. A first order expression suitable for small, dense lumps was set out, primarily for instructive reasons, but this is not a restriction of the method. The method is readily scaleable to material of different isotopic composition, density and a. Numerical parameters suitable for practical applications have been established and we feel the approach is fit for the intended purpose reflecting operational experiences and the general state of knowledge of waste items. (authors)

  20. Atacama Cosmology Telescope: Extragalactic Sources at 148 GHz in the 2008 Survey

    CERN Document Server

    Marriage, T A; Lin, Y -T; Marsden, D; Nolta, M R; Partridge, B; Ade, P A R; Aguirre, P; Amiri, M; Appel, J W; Barrientos, L F; Battistelli, E S; Bond, J R; Brown, B; Burger, B; Chervenak, J; Das, S; Devlin, M J; Dicker, S R; Doriese, W B; Dunkley, J; Dunner, R; Essinger-Hileman, T; Fisher, R P; Fowler, J W; Hajian, A; Halpern, M; Hasselfield, M; Hernandez-Monteagudo, C; Hilton, G C; Hilton, M; Hincks, A D; Hlozek, R; Huffenberger, K M; Hughes, D H; Hughes, J P; Infante, L; Irwin, K D; Kaul, M; Klein, J; Kosowsky, A; Lau, J M; Limon, M; Lupton, R H; Martocci, K; Mauskopf, P; Menanteau, F; Moodley, K; Moseley, H; Netterfield, C B; Niemack, M D; Page, L A; Parker, L; Quintana, H; Reid, B; Sehgal, N; Sherwin, B D; Sievers, J; Spergel, D N; Staggs, S T; Swetz, D S; Switzer, E R; Thornton, R; Trac, H; Tucker, C; Warne, R; Wilson, G; Wollack, E; Zhao, Y

    2010-01-01

    We report on extragalactic sources detected in a 455 square-degree map of the southern sky made with data at a frequency of 148 GHz from the Atacama Cosmology Telescope 2008 observing season. We provide a catalog of 157 sources with flux densities spanning two orders of magnitude: from 15 to 1500 mJy. Comparison to other catalogs shows that 98% of the ACT detections correspond to sources detected at lower radio frequencies. Three of the sources appear to be associated with the brightest cluster galaxies of low redshift X-ray selected galaxy clusters. Estimates of the radio to mm-wave spectral indices and differential counts of the sources further bolster the hypothesis that they are nearly all radio sources, and that their emission is not dominated by re-emission from warm dust. In a bright (>50 mJy) 148 GHz-selected sample with complete cross-identifications from the Australia Telescope 20 GHz survey, we observe an average steepening of the spectra between 5, 20, and 148 GHz with median spectral indices of $...

  1. Estudos da linguagem e mente corporificada: uma nova proposta gramatical Studies of language and embodied mind: a new grammar approach

    Directory of Open Access Journals (Sweden)

    Ricardo Yamashita Santos

    2011-01-01

    Full Text Available Podemos dizer que Descartes fundamentou a filosofia moderna com uma proposta universal do entendimento mundano. Dissociando as experiências corpóreas de nossa matéria pensante - mente, conseguiríamos captar a verdadeira essência de tudo por meio de um pensamento racional e objetivo. A ideia de mente corporificada, traduzida aqui pelos moldes de Lakoff e Johnson (1980, quebra com a dicotomia do filósofo e com diversas outras tradições enraizadas em nossa cultura ocidental. Nosso objetivo neste artigo é o de amparar a nova proposta teórica de mente corporificada e pensar um novo modelo gramatical que evidencie a corporalidade da mente.We can say that Descartes founded the modern philosophy with an universal proposal of the mundane understanding. Dissociating the bodily experience from our thinking matter - mind, we could capture the true essence of everything through rational and objective thought. The idea of the embodied mind, translated here by Lakoff and Johnson's theories (1980, breaks Descartes' dichotomy and various other traditions rooted in our Western culture. Our goals in this paper is to bolster the new theoretical proposition of embodied mind and think about a new grammatical model that highlights the embodiment of mind.

  2. “Recovering our Stories”: A Small Act of Resistance

    Directory of Open Access Journals (Sweden)

    Lucy Costa

    2012-10-01

    Full Text Available This paper describes a community event organized in response to the appropriation and overreliance on the psychiatric patient “personal story” within mental health organizations. The sharing of experiences through stories by individuals who self-identify as having “lived experience” has been central to the history of organizing for change in and outside of the psychiatric system. However, in the last decade, personal stories have increasingly been used by the psychiatric system to bolster research, education, and fundraising interests. We explore how personal stories from consumer/survivors have been harnessed by mental health organizations to further their interests and in so doing have shifted these narrations from “agents of change” towards one of “disability tourism” or “patient porn.” We mark the ethical dilemmas of narrative cooptation and consumption, and query how stories of resistance can be reclaimed not as personal recovery narratives but rather as a tool for socio-political change.

  3. Pseudocyst of the auricle: an uncommon entity of the ear.

    Science.gov (United States)

    Sheaffer, Alexis; Sahu, Joya; Lee, Jason B

    2012-01-01

    A 48-year-old white man presented with a 2-month history of a lump on his right ear following purported exposure to the cold. The patient denied any history of trauma, rubbing, insect bite, or inflammation at the site. The patient was otherwise healthy and was not taking any medications. The lesion was completely asymptomatic, as the patient denied any pain, tenderness, or change in size since the lesion appeared. Physical examination revealed a 1.1-cm x 1-cm skin-colored, slightly fluctuant, rubbery, nonmobile dermal nodule on the right scaphoid fossa (Figure 1). No erythema, warmth, tenderness, or drainage was noted. A review of systems was noncontributory. A punch biopsy performed at the site of the cyst yielded clear, serous drainage. The cystic lesion was drained completely and decompressed. Histological examination revealed the surface of an intracartilaginous cystic space lined by degenerated cartilage, consistent with a diagnosis of pseudocyst of the auricle (Figure 2 and Figure 3). The lesion, although much smaller than at the time of presentation, persisted at the 3-week follow-up visit. It remained asymptomatic, without pain or irritation. At that time, the patient declined re-excision with bolster dressing. At 7-month follow-up, he reported the lesion to be stable.

  4. Dinosaur Peptides Suggest Mechanisms of Protein Survival

    Energy Technology Data Exchange (ETDEWEB)

    San Antonio, James D.; Schweitzer, Mary H.; Jensen, Shane T.; Kalluri, Raghu; Buckley, Michael; Orgel, Joseph P.R.O. (Harvard-Med); (IIT); (NCSU); (UPENN); (Manchester); (Orthovita)

    2011-09-16

    Eleven collagen peptide sequences recovered from chemical extracts of dinosaur bones were mapped onto molecular models of the vertebrate collagen fibril derived from extant taxa. The dinosaur peptides localized to fibril regions protected by the close packing of collagen molecules, and contained few acidic amino acids. Four peptides mapped to collagen regions crucial for cell-collagen interactions and tissue development. Dinosaur peptides were not represented in more exposed parts of the collagen fibril or regions mediating intermolecular cross-linking. Thus functionally significant regions of collagen fibrils that are physically shielded within the fibril may be preferentially preserved in fossils. These results show empirically that structure-function relationships at the molecular level could contribute to selective preservation in fossilized vertebrate remains across geological time, suggest a 'preservation motif', and bolster current concepts linking collagen structure to biological function. This non-random distribution supports the hypothesis that the peptides are produced by the extinct organisms and suggests a chemical mechanism for survival.

  5. Worldwide Engagement for Sustainable Energy Strategies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-01

    Almost 40 years after the Agency’s founding, the IEA responsibility for ensuring access to global oil supplies is still a core mandate. Yet over the course of its history, the IEA’s responsibilities have expanded along with both the international energy economy and conceptions of energy security itself. Our mission to promote secure and sustainable energy provision spans the energy mix. At the same time, a changing global energy map means that the industrialised nations of the world no longer dominate energy consumption. The IEA must work in close co-operation with partner countries and organisations worldwide to achieve its three core objectives: energy security, economic prosperity, and environmental sustainability. Working toward international commitments to reduce greenhouse gas emissions that cause global climate change; facilitating energy technology exchange, innovation and deployment; improving modern energy access to the billions of people who are without it; bolstering both cleanliness and security through energy efficiency; and promoting flexible and functioning energy markets – these efforts complement our traditional core responsibilities of mitigating the effects of supply disruptions and improving statistical transparency.

  6. Spectroscopy of Young Planetary Mass Candidates with Disks

    CERN Document Server

    Jayawardhana, R; Jayawardhana, Ray; Ivanov, Valentin D.

    2006-01-01

    It is now well established that many young brown dwarfs exhibit characteristics similar to classical T Tauri stars, including infrared excess from disks and emission lines related to accretion. Whether the same holds true for even lower mass objects, namely those near and below the Deuterium-burning limit, is an important question. Here we present optical spectra of six isolated planetary mass candidates in Chamaeleon II, Lupus I and Ophiuchus star-forming regions, recently identified by Allers and collaborators to harbor substantial mid-infrared excesses. Our spectra, from ESO's Very Large Telescope and New Technology Telescope, show that four of the targets have spectral types in the ~M9-L1 range, and three of those also exhibit H_alpha. Their luminosities are consistent with masses of ~5-15 M_{Jupiter} according to models of Chabrier, Baraffe and co-workers, thus placing these four objects among the lowest mass brown dwarfs known to be surrounded by circum-sub-stellar disks. Our findings bolster the idea t...

  7. National Alliance for Radiation Readiness: Leveraging Partnerships to Increase Preparedness.

    Science.gov (United States)

    Blumenstock, James S; Allen, Meredith

    2016-02-01

    The National Alliance for Radiation Readiness (NARR) is an alliance of 16 national member organizations that have banded together to serve as the collective "voice of health" in radiological preparedness through: • participation in national dialogues on radiological emergency issues; • provision of thoughtful feedback on documents, policies, and guidelines; and • convening of partners to raise awareness of and resolve radiological emergency issues. NARR benefits from the intersection and interaction of public health, radiation control, healthcare, and emergency management professionals--all with an interest in bolstering the nation's preparedness for a radiological or nuclear incident. NARR is able to provide a unique perspective on radiological and nuclear preparedness by creating multi-disciplinary workgroups to develop guidance, recommendations, and provide subject matter feedback. NARR aims to build response and recovery capacity and capabilities by supporting the sharing of resources and tools, including technical methods and information through the development of an online clearinghouse. NARR also aims to identify and disseminate best practices, as well as define and educate on the roles and responsibilities of local, state, and federal government and the numerous agencies involved with the response to a radiological emergency.

  8. A dual-systems perspective on addiction: contributions from neuroimaging and cognitive training.

    Science.gov (United States)

    McClure, Samuel M; Bickel, Warren K

    2014-10-01

    Dual-systems theories explain lapses in self-control in terms of a conflict between automatic and deliberative modes of behavioral control. Numerous studies have now tested whether the brain areas that control behavior are organized in a manner consistent with dual-systems models. Brain regions directly associated with the mesolimbic dopamine system, the nucleus accumbens and ventromedial prefrontal cortex in particular, capture some of the features assumed by automatic processing. Regions in the lateral prefrontal cortex are more closely linked to deliberative processing and the exertion of self-control in the suppression of impulses. While identifying these regions crudely supports dual-systems theories, important modifications to what constitutes automatic and deliberative behavioral control are also suggested. Experiments have identified various means by which automatic processes may be sculpted. Additional work decomposes deliberative processes into component functions such as generalized working memory, reappraisal of emotional stimuli, and prospection. The importance of deconstructing dual-systems models into specific cognitive processes is clear for understanding and treating addiction. We discuss intervention possibilities suggested by recent research, and focus in particular on cognitive training approaches to bolster deliberative control processes that may aid quit attempts. PMID:25336389

  9. Defining Socially-Based Spatial Boundaries in the Region of Peel, Ontario, Canada

    Directory of Open Access Journals (Sweden)

    Newbold K Bruce

    2011-05-01

    Full Text Available Abstract Background The purpose of the project was to delineate a series of contiguous neighbourhood-based "Data Zones" within the Region of Peel (Ontario for the purpose of health data analysis and dissemination. Zones were to be built on Census Tracts (N = 205 and obey a series of requirements defined by the Region of Peel. This paper explores a method that combines statistical analysis with ground-truthing, consultation, and the use of a decision tree. Data Census Tract data for Peel were derived from the 2006 Canadian Census Master file. Methods Following correlation analysis to reduce the data set, Principal Component Analysis was applied to the data set to reduce the complexity and derive an index. The Getis-Ord Gi*statistic was then applied to look for statistically significant clusters of like Census Tracts. A detailed decision tree for the amalgamation of remaining zones and ground-truthing with Peel staff verified the resulting zones. Results A total of 15 Data Zones that are similar with respect to socioeconomic and sociodemographic attributes and that met criteria defined by Peel were derived for the region. Conclusion The approach used in this analysis, which was bolstered by a series of checks and balances throughout the process, gives statistical validity to the defined zones and resulted in a robust series of Data Zones for use by Peel Public Health. We conclude by offering insight into alternative uses of the methodology, and limitations.

  10. Regulatory T Cells in Colorectal Cancer: From Biology to Prognostic Relevance

    Directory of Open Access Journals (Sweden)

    Dimitrios Mougiakakos

    2011-03-01

    Full Text Available Regulatory T cells (Tregs were initially described as "suppressive" lymphocytes in the 1980s. However, it took almost 20 years until the concept of Treg-mediated immune control in its present form was finally established. Tregs are obligatory for self-tolerance and defects within their population lead to severe autoimmune disorders. On the other hand Tregs may promote tolerance for tumor antigens and even hamper efforts to overcome it. Intratumoral and systemic accumulation of Tregs has been observed in various types of cancer and is often linked to worse disease course and outcome. Increase of circulating Tregs, as well as their presence in mesenteric lymph nodes and tumor tissue of patients with colorectal cancer de facto suggests a strong involvement of Tregs in the antitumor control. This review will focus on the Treg biology in view of colorectal cancer, means of Treg accumulation and the controversies regarding their prognostic significance. In addition, a concise overview will be given on how Tregs and their function can be targeted in cancer patients in order to bolster an inherent immune response and/or increase the efficacy of immunotherapeutic approaches.

  11. Programming iOS 6

    CERN Document Server

    Neuburg, Matt

    2013-01-01

    Get a solid grounding in all the fundamentals of Cocoa Touch, and avoid problems during iPhone and iPad app development. With this revised and expanded edition, you'll dig into Cocoa and learn how to work effectively with Objective-C and Xcode. This book covers iOS 6 in a rigorous, orderly fashion-ideal whether you're approaching iOS for the first time or need a reference to bolster existing skills. Learn about features introduced with iOS 6, including Objective-C language advances, autosynthesis, autolayout, new view controller rotation rules, unwind segues, state restoration, styled text, and collection views. * Learn Objective-C language details and object-oriented programming concepts * Understand the anatomy of an Xcode project and all the stages of its lifecycle * Grasp key Cocoa concepts such as relationships between classes, receiving events, and model-view-controller architecture * Learn how views and layers are managed, drawn, composited, and animated * Become familiar with view controllers and thei...

  12. Cognitive empathy contributes to poor social functioning in schizophrenia: Evidence from a new self-report measure of cognitive and affective empathy.

    Science.gov (United States)

    Michaels, Tania M; Horan, William P; Ginger, Emily J; Martinovich, Zoran; Pinkham, Amy E; Smith, Matthew J

    2014-12-30

    Cognitive empathy impairments have been linked to poor social functioning in schizophrenia. However, prior studies primarily used self-reported empathy measures developed decades ago that are not well-aligned with contemporary models of empathy. We evaluated empathy and its relationship to social functioning in schizophrenia using the recently developed Questionnaire of Cognitive and Affective Empathy (QCAE). Schizophrenia (n=52) and healthy comparison (n=37) subjects completed the QCAE, Interpersonal Reactivity Index (IRI), and measures of neurocognition, symptoms, and social functioning. Between-group differences on the QCAE, and relationships between QCAE and IRI subscales, neurocognition, symptoms, and social functioning were examined. The schizophrenia group reported significantly lower cognitive empathy than comparison subjects, which was driven by low online simulation scores. Cognitive empathy explained significant variance in social functioning after accounting for neurocognition and symptoms. Group differences for affective empathy were variable; the schizophrenia group reported similar proximal responsivity, but elevated emotion contagion relative to comparison subjects. These findings bolster support for the presence and functional significance of impaired cognitive empathy in schizophrenia using a contemporary measure of empathy. Emerging evidence that some aspects of affective empathy may be unimpaired or hyper-responsive in schizophrenia and implications for the assessment and treatment of empathy in schizophrenia are discussed.

  13. Power and death: Mortality salience increases power seeking while feeling powerful reduces death anxiety.

    Science.gov (United States)

    Belmi, Peter; Pfeffer, Jeffrey

    2016-05-01

    According to Terror Management Theory, people respond to reminders of mortality by seeking psychological security and bolstering their self-esteem. Because previous research suggests that having power can provide individuals a sense of security and self-worth, we hypothesize that mortality salience leads to an increased motivation to acquire power, especially among men. Study 1 found that men (but not women) who wrote about their death reported more interest in acquiring power. Study 2A and Study 2B demonstrated that when primed with reminders of death, men (but not women) reported behaving more dominantly during the subsequent week, while both men and women reported behaving more prosocially during that week. Thus, mortality salience prompts people to respond in ways that help them manage their death anxiety but in ways consistent with normative gender expectations. Furthermore, Studies 3-5 showed that feeling powerful reduces anxiety when mortality is salient. Specifically, we found that when primed to feel more powerful, both men and women experienced less mortality anxiety. (PsycINFO Database Record PMID:26867106

  14. Then I started thinking: A qualitative study of innovative projects by secondary students in STEM disciplines

    Science.gov (United States)

    Haggerty, Rebecca

    This qualitative bounded case study examined the self-described motivations of 14 finalists in an international science fair, eight male and six female, between the ages of 15 and 19, from Spain, Ukraine, India, Singapore, Australia, Canada, and the United States. The study used semi-structured interviews and document review to explore participant motivation for undertaking complex research in math and science. Participants reported being highly motivated to pursue their projects, which they found intrinsically interesting and valuable. They enjoyed the benefits that ensued from their science fair activities, including prizes and acclaim, social camaraderie, a satisfying sense of accomplishment and independence, and access to well-known and established practitioners in the field. Female participants experienced a comfortable gender balance in science fairs. Prosocial motivations, and the opportunity to have a positive impact on the world, emerged from the findings as important factors in stimulating the creativity of many participants as well as in bolstering their persistence. Participants showed adaptive patterns of attributions as well as high self-efficacy. They successfully strategized to overcome setbacks, and drew upon their available resources of family, school, and community support to develop and sustain their interest.

  15. A Review of the Water and Energy Sectors and the Use of a Nexus Approach in Abu Dhabi

    Science.gov (United States)

    Paul, Parneet; Al Tenaiji, Ameena Kulaib; Braimah, Nuhu

    2016-01-01

    Rapid population increase coupled with urbanization and industrialization has resulted in shortages of water in the Middle East. This situation is further exacerbated by global climate change due to greenhouse gas emissions. Recent research advocates that solutions to the global water security and scarcity crisis must involve water–energy nexus approaches. This means adopting policies and strategies that harmonize these inter-related sectors to minimize environmental impact while maximizing human benefit. In the case of Abu Dhabi, when designing and locating oil/gas refineries and associated power generation facilities, previous relevant decisions were based on simple economic and geographical grounds, such as nearness to oil rigs, pipelines, existing industries and port facilities, etc. The subsequent design and location of water abstraction and treatment works operated by the waste heat from these refining and/or power generation processes was catered for as an afterthought, meaning that there is now a mismatch between the water and energy supplies and demands. This review study was carried out to show how Abu Dhabi is trying now to integrate its water–energy sectors using a nexus approach so that future water/power infrastructure is designed optimally and operated in harmony, especially in regard to future demand. Based upon this review work, some recommendations are made for designers and policy makers alike to bolster the nexus approach that Abu Dhabi is pursuing. PMID:27023583

  16. Public trust in the healthcare system in a developing country.

    Science.gov (United States)

    Peters, Dexnell; Youssef, Farid F

    2016-04-01

    Broadly defined, trust in the healthcare system is concerned with how the public perceives the system and the actors therein as it pertains to their ability to both deliver services and seek the best interests of their clientele. Trust is important because it impacts upon a range of health behaviors including compliance and ultimately affects the ability of the healthcare system to meet its goals. While several studies exist on public trust within the developed world, few studies have explored this issue in developing countries. This paper therefore assesses public trust in the healthcare system of a developing small island nation, Trinidad and Tobago. A cross-sectional survey of adults was conducted using a questionnaire that has been successfully used across Europe. We report that trust levels in the healthcare system in Trinidad and Tobago are relatively low with less than 50% of persons indicating fair trust in the healthcare system. In addition, individual health professionals also did not score highly with lowest scores found for nurses and complementary therapists. Results on four out of five dimensions of trust also demonstrated scores significantly lower than those reported in more developed nations. Open-ended comments supported these findings with the majority of persons indicating a lack of confidence in the healthcare system. These results may reflect the reality in the wider developing world, and we suggest that bolstering trust is a needed area of focus in the delivery of healthcare services throughout the nation. Copyright © 2014 John Wiley & Sons, Ltd.

  17. Extending the Reach of Early Intervention Training for Practitioners: A Preliminary Investigation of an Online Curriculum for Teaching Behavioral Intervention Knowledge in Autism to Families and Service Providers.

    Science.gov (United States)

    Hamad, Charles D; Serna, Richard W; Morrison, Leslie; Fleming, Richard

    2010-07-01

    Early behavioral intervention, based on the methods of applied behavior analysis, has the strongest and most consistent scientific support as a means of teaching skills to young children with Autism Spectrum Disorder and reducing their restricted and maladaptive behavior. Though individual ABA-based treatment plans are usually developed, designed and supervised by a senior-level clinician, they are most often implemented by a practitioner, such as a parent, direct service provider, aide, or an early childhood professional from a related discipline. Unfortunately, few practitioner-orientated training programs are available to geographically disparate persons. Online distance-learning education offers a potential solution to this problem. Fifty-one individuals participated in an initial study of a short, three-module online course. The results showed a highly statistically significant difference between the mean pre-test and post-test score. The outcomes suggest the feasibility and user satisfaction of teaching BI knowledge acquisition online, and thus bolster confidence that future, larger-scale curricula aimed at teaching BI in a distance-learning format is warranted. PMID:23504540

  18. An effective workplace stress management intervention: Chicken Soup for the Soul at Work Employee Groups.

    Science.gov (United States)

    Horan, Anne Puidk

    2002-01-01

    Stress is a costly and significant source of health problems and mental distress--with work cited as a primary stressor. This pilot study supports the effectiveness of a new workplace stress intervention: Chicken Soup for the Soul at Work Employee Groups. In this program, employee-participants met during nine weekly meetings to read inspirational workplace stories, comment, and share their own stories. A leader, chosen from and by the group, guided meetings. Utilizing a wait-list control group design, participants were randomly assigned to an experimental or wait-list group. Participants completed pretests and posttests (Coping Resources Inventory, Occupational Stress Inventory-Revised, Job Descriptive Index, Pressure Management Indicator, survey). Statistical interaction effect for subtests was evaluated using a two-way repeated measures analysis of variance. Participants exhibited improved total coping resources, cognitive/rational coping, state of mind, confidence and home/work balance. Participant comments and their continued participation in a similar company-sponsored program bolster these empirical results.

  19. DISCOVERY OF THE HOST CLUSTER FOR THE FUNDAMENTAL CEPHEID CALIBRATOR ZETA GEMINORUM

    International Nuclear Information System (INIS)

    New and existing CORAVEL, UBVJHKs , HST, HIP/Tycho, ARO, KPNO, and DAO observations imply that the fundamental Cepheid calibrator ζ Gem is a cluster member. The following parameters were inferred for ζ Gem from cluster membership and are tied to new spectral classifications (DAO) established for 26 nearby stars (e.g., HD53588/B7.5IV, HD54692/B9.5IV): EB–V = 0.02 ± 0.02, log τ = 7.85 ± 0.15, and d = 355 ± 15 pc. The mean distance to ζ Gem from cluster membership and six recent estimates (e.g., IRSB) is d=363±9(σx-bar )±26 (σ) pc. The results presented here support the color-excess and HST parallax derived for the Cepheid by Benedict et al. Forthcoming precise proper motions (DASCH) and Chandra/XMM-Newton observations of the broader field may be employed to identify cluster members, bolster the cluster's existence, and provide stronger constraints on the Cepheid's fundamental parameters.

  20. NEW EVIDENCE SUPPORTING CLUSTER MEMBERSHIP FOR THE KEYSTONE CALIBRATOR DELTA CEPHEI

    International Nuclear Information System (INIS)

    New and existing UBVJHKs , spectroscopic, NOMAD, Hubble Space Telescope, and revised Hipparcos observations are employed to determine properties for δ Cep and its host star cluster. The multi-faceted approach ensured that uncertainties were mitigated (σ/d ∼ 2%). The following fundamental parameters were inferred for δ Cep: E(B – V) = 0.073 ± 0.018(σ), log τ = 7.9 ± 0.1, and d=272 ± 3(σx-bar) ± 5 (σ) pc. The cluster exhibits a turnoff near B6 (M*/M☉ ∼ 5), and the brightest host cluster members are the supergiants ζ Cep (K1.5Ib) and δ Cep. To within the uncertainties, the two stars share common astrometric parameters (π, μα, μδ, RV ∼ –17 km s–1) and are tied to bluer members via the evolutionary track implied by the cluster's UBVJHKs color-color and color-magnitude diagrams. The cluster's existence is bolstered by the absence of an early-type sequence in color-magnitude diagrams for comparison fields. NOMAD data provided a means to identify potential cluster members (n ∼ 30) and double the existing sample. That number could increase with forthcoming precise proper motions (DASCH) for fainter main-sequence stars associated with classical Cepheids (e.g., δ Cep), which may invariably foster efforts to strengthen the Galactic Cepheid calibration and reduce uncertainties tied to H0.

  1. The Dynamics of Brownfield Redevelopment

    Directory of Open Access Journals (Sweden)

    Mark Paich

    2011-06-01

    Full Text Available Negligence of former industrial sites (“brownfields” has adversely impacted urban landscapes throughout the industrialized world. Brownfield redevelopment has recently emerged as a sustainable land use strategy and impetus for urban revitalization. This study presents a system dynamics model of the redevelopment process that illustrates how delays compound before realizing financial benefits from investment in these core urban areas. We construct a dynamic hypothesis, in which brownfield redevelopment activities are dependent upon funding and in turn bolster tax base through job creation. Drawing on previous studies, barriers to brownfield redevelopment are explored, including fear of liability, regulatory concerns, and uncertain cleanup standards and funding mechanisms. We model a case study of redevelopment in the State of Michigan (USA, which is informed by data from the Department of Environmental Quality (MDEQ and U.S. Conference of Mayors brownfield surveys. Stock-flow structures represent phases of redevelopment, with diverted streams for sites in which no contamination was found (false alarms and those with excess contamination level. The model is used to examine the point at which cumulative tax revenues from redeveloped areas exceed cumulative expenditures on brownfield redevelopment under different levels of funding availability.

  2. Explaining participation of private forest owners in economic incentives. Case studies in Europe

    DEFF Research Database (Denmark)

    Górriz, E.; Mäntymaa, E.; Petucco, C.;

    2014-01-01

    Taking part in the implementation of a voluntary policy instrument for land use management implies motivational requirements of the targeted landowner. Increasing knowledge on the potential economic, managerial and attitudinal factors helps design incentives in accordance and facilitates an effec......Taking part in the implementation of a voluntary policy instrument for land use management implies motivational requirements of the targeted landowner. Increasing knowledge on the potential economic, managerial and attitudinal factors helps design incentives in accordance and facilitates...... an effective performance. We analyzed surveys and interviews addressed to private forest owners, at country or regional level in five European countries. Participation rates for different schemes aimed at enhancing the provision of ecosystem services were contrasted with a range of landowners’ socio-economic...... objectives or the land management measures they promote. It demonstrates that the design of mechanisms bolstering synergies between current landowners’ practices and expectations to those demanded by externals have more likelihood of success than those implying drastic management changes. On the other hand...

  3. Improved prediction of antibody VL-VH orientation.

    Science.gov (United States)

    Marze, Nicholas A; Lyskov, Sergey; Gray, Jeffrey J

    2016-10-01

    Antibodies are important immune molecules with high commercial value and therapeutic interest because of their ability to bind diverse antigens. Computational prediction of antibody structure can quickly reveal valuable information about the nature of these antigen-binding interactions, but only if the models are of sufficient quality. To achieve high model quality during complementarity-determining region (CDR) structural prediction, one must account for the VL-VH orientation. We developed a novel four-metric VL-VH orientation coordinate frame. Additionally, we extended the CDR grafting protocol in RosettaAntibody with a new method that diversifies VL-VH orientation by using 10 VL-VH orientation templates rather than a single one. We tested the multiple-template grafting protocol on two datasets of known antibody crystal structures. During the template-grafting phase, the new protocol improved the fraction of accurate VL-VH orientation predictions from only 26% (12/46) to 72% (33/46) of targets. After the full RosettaAntibody protocol, including CDR H3 remodeling and VL-VH re-orientation, the new protocol produced more candidate structures with accurate VL-VH orientation than the standard protocol in 43/46 targets (93%). The improved ability to predict VL-VH orientation will bolster predictions of other parts of the paratope, including the conformation of CDR H3, a grand challenge of antibody homology modeling.

  4. REVERBERATION MAPPING OF A LOW-MASS BLACK HOLE IN A NARROW-LINE SEYFERT 1 GALAXY

    International Nuclear Information System (INIS)

    We present results of a reverberation mapping (RM) campaign on the low black hole mass narrow-line Seyfert 1 (NLS1) galaxy SDSS J113913.91+335551.1 (hereafter SL01). Using the Hβ measurements, we find a time lag τ= 12.5+0.5-11 days and a broad-line velocity width of 1450 km s–1 which implies a black hole mass of 3.8+0.6-2.8×106 M☉. To further bolster our time lag results, we employ a secondary method based on the multivariate correlation function as described in Chelouche and Zucker, in which case we obtain consistent lags for the Balmer lines, yet without the need to spectrally deconvolve line from continuum emission processes. Given SL01's luminosity (Lbol ≈ 7 × 1043 erg s–1), we estimate an Eddington ratio (Lbol/LEdd) of ∼0.18. This fairly low-mass determination and rather high Lbol/LEdd is consistent with the current paradigm that the nuclei of NLS1 galaxies host small black holes (as low as 106 M☉) with high accretion rates. SL01 is one of only a few NLS1s to date with robust RM results

  5. Results of a Technical Review of the U.S. Climate Change Technology Program's R&D Portfolio

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Marilyn A [ORNL

    2006-07-01

    The U.S. Climate Change Technology Program (CCTP) is a multi-agency planning and coordinating entity, led by the U.S. Department of Energy that aims to accelerate the development and facilitate the adoption of technologies to address climate change. In late 2005, CCTP asked Oak Ridge National Laboratory and Energetics Incorporated to organize and coordinate a review of the CCTP R&D portfolio using structured workshops. Each workshop focused on one of CCTP's six strategic goals: 1.Reduce emissions from energy end-use and infrastructure 2.Reduce emissions from energy supply 3.Capture and sequester carbon dioxide 4.Reduce emissions of non-CO2 greenhouse gases (GHG) 5.Improve capabilities to measure and monitor GHG emissions 6.Bolster basic science contributions to technology development To promote meaningful dialogue while ensuring broad coverage, a group of broadly experienced professionals with expertise in fields relevant to each CCTP goal were asked to participate in the portfolio reviews and associated workshops. A total of 75 experts participated in the workshops; 60 of these participants represented non-Federal organizations. This report summarizes the findings of the workshops and the results of the Delphi assessment of the CCTP R&D portfolio.

  6. Shared Illness and Social Support Within Two HIV-Affected African American Communities.

    Science.gov (United States)

    Mosack, Katie E; Stevens, Patricia E; Brouwer, Amanda M; Wendorf, Angela R

    2016-09-01

    A key source of resiliency within HIV-affected African American communities is informal social support. Data from dyadic conversations and focus groups were used to address the following research question: What are HIV-positive African Americans' social support experiences within their informal social networks in response to HIV-related problems? Circumstances that exacerbated HIV-related problems included others' fear of contagion, reticence to be involved, judgment and rejection, and disregard for privacy Support from HIV-negative others buffered the impact of problems when others communicate interest, take the initiative to help, or make a long-term investment in their success. Support from other HIV-positive persons was helpful given the shared connection because of HIV, the opportunity to commiserate about what is mutually understood, and the fight for mutual survival Based on these findings, we offer suggestions for future research and social network interventions aimed at bolstering connections between HIV-positive peers, reducing stigma, and improving family support. PMID:26515921

  7. The Alliance Negotiation Scale: A psychometric investigation.

    Science.gov (United States)

    Doran, Jennifer M; Safran, Jeremy D; Muran, J Christopher

    2016-08-01

    This study investigates the utility and psychometric properties of a new measure of psychotherapy process, the Alliance Negotiation Scale (ANS; Doran, Safran, Waizmann, Bolger, & Muran, 2012). The ANS was designed to operationalize the theoretical construct of negotiation (Safran & Muran, 2000), and to extend our current understanding of the working alliance concept (Bordin, 1979). The ANS was also intended to improve upon existing measures such as the Working Alliance Inventory (WAI; Horvath & Greenberg, 1986, 1989) and its short form (WAI-S; Tracey & Kokotovic, 1989) by expanding the emphasis on negative therapy process. The present study investigates the psychometric validity of the ANS test scores and interpretation-including confirming its original factor structure and evaluating its internal consistency and construct validity. Construct validity was examined through the ANS' convergence and divergence with several existing scales that measure theoretically related constructs. The results bolster and extend previous findings about the psychometric integrity of the ANS, and begin to illuminate the relationship between negotiation and other important variables in psychotherapy research. (PsycINFO Database Record

  8. Towards new business models for R&D for novel antibiotics.

    Science.gov (United States)

    So, A D; Gupta, N; Brahmachari, S K; Chopra, I; Munos, B; Nathan, C; Outterson, K; Paccaud, J P; Payne, D J; Peeling, R W; Spigelman, M; Weigelt, J

    2011-04-01

    In the face of a growing global burden of resistance to existing antibiotics, a combination of scientific and economic challenges has posed significant barriers to the development of novel antibacterials over the past few decades. Yet the bottlenecks at each stage of the pharmaceutical value chain-from discovery to post-marketing-present opportunities to reengineer an innovation pipeline that has fallen short. The upstream hurdles to lead identification and optimization may be eased with greater multi-sectoral collaboration, a growing array of alternatives to high-throughput screening, and the application of open source approaches. Product development partnerships and South-South innovation platforms have shown promise in bolstering the R&D efforts to tackle neglected diseases. Strategies that delink product sales from the firms' return on investment can help ensure that the twin goals of innovation and access are met. To effect these changes, both public and private sector stakeholders must show greater commitment to an R&D agenda that will address this problem, not only for industrialized countries but also globally. PMID:21439891

  9. Inside the whale: the structure and dynamics of the isolated Cetus dwarf spheroidal

    CERN Document Server

    Lewis, G F; Chapman, S C; McConnachie, A; Irwin, M J; Tolstoy, E; Tanvir, N R

    2006-01-01

    This paper presents a study of the Cetus dwarf, an isolated dwarf galaxy within the Local Group. A matched-filter analysis of the INT/WFC imaging of this system reveals no evidence for significant tidal debris that could have been torn from the galaxy, bolstering the hypothesis that Cetus has never significantly interacted with either the Milky Way or M31. Additionally, Keck/Deimos spectroscopic observations identify this galaxy as a distinct kinematic population possessing a systematic velocity of $-87\\pm2{\\rm km\\ s^{-1}}$ and with a velocity dispersion of $17\\pm2{\\rm km s^{-1}}$; while tentative, these data also suggest that Cetus possesses a moderate rotational velocity of $\\sim8{\\rm km s^{-1}}$. The population is confirmed to be relatively metal-poor, consistent with ${\\rm [Fe/H]\\sim-1.9}$, and, assuming virial equilibrium, implies that the Cetus dwarf galaxy possesses a $M/L\\sim70$. It appears, therefore, that Cetus may represent a primordial dwarf galaxy, retaining the kinematic and structural propertie...

  10. Financial Bubbles, Real Estate Bubbles, Derivative Bubbles, and the Financial and Economic Crisis

    Science.gov (United States)

    Sornette, Didier; Woodard, Ryan

    The financial crisis of 2008, which started with an initially well-defined epicenter focused on mortgage backed securities (MBS), has been cascading into a global economic recession, whose increasing severity and uncertain duration has led and is continuing to lead to massive losses and damage for billions of people. Heavy central bank interventions and government spending programs have been launched worldwide and especially in the USA and Europe, with the hope to unfreeze credit and bolster consumption. Here, we present evidence and articulate a general framework that allows one to diagnose the fundamental cause of the unfolding financial and economic crisis: the accumulation of several bubbles and their interplay and mutual reinforcement have led to an illusion of a "perpetual money machine" allowing financial institutions to extract wealth from an unsustainable artificial process. Taking stock of this diagnostic, we conclude that many of the interventions to address the so-called liquidity crisis and to encourage more consumption are ill-advised and even dangerous, given that precautionary reserves were not accumulated in the "good times" but that huge liabilities were. The most "interesting" present times constitute unique opportunities but also great challenges, for which we offer a few recommendations.

  11. Albanian legal framework on Factoring contract

    Directory of Open Access Journals (Sweden)

    Anjeza Liçenji

    2013-07-01

    Full Text Available Factoring contract is a new phenomenon, compared to earlier forms of commerce in juridical circulation. Factoring is a method used by a firm to obtain cash when available cash balance, held by the firm, is insufficient to meet current obligations, and accommodate its other cash needs, such as new orders or contracts. The use of factoring to obtain the cash, needed to accommodate the firm’s immediate cash needs, will allow the firm to maintain a smaller ongoing cash balance. By reducing the size of its cash balances, more money becomes available for investment in the firm’s growth. A company sells its invoices at discount to their face value when it calculates that it will be better off proceeding to bolster its own growth than it would be by effectively functioning as its “customer’s bank”. Many businesses have cash flow that varies. A business might have a relatively large cash flow in one period, as well as a relatively small cash flow in another period. Because of this, firms find it necessary to both keep a cash balance on hand, and use such methods as factoring, in order to enable them to cover their short term cash needs in those periods in which these needs exceed cash flow.

  12. Leveraging the Experiences of Informal Caregivers to Create Future Healthcare Workforce Options.

    Science.gov (United States)

    Phillips, Sara S; Ragas, Daiva M; Hajjar, Nadia; Tom, Laura S; Dong, XinQi; Simon, Melissa A

    2016-01-01

    The objective of this study was gather pilot data from informal caregivers regarding the potential for a training program to assist current or past caregivers in reentering the job market, and thus offering a pathway to economic resilience. In an effort that could foster a sustainable and competent caregiving market to help meet the needs of an aging America, whether training informal caregivers might help them transition into a paid caregiving or other health service role was explored. Caregivers (N=55) of a chronically or terminally ill family member or friend in a suburban county near Chicago were interviewed. The interview guide addressed household economic effect of illness, emotional burden, and training program interest. Fifty-six percent of caregivers were interested in training to work outside the home, caring for people in other households, 84% indicated a desire to learn more about health care, and 68% reported a desire to explore job possibilities in health care. Eighty-two percent were experienced in working with an individual aged 50 and older. Informal caregivers' interest in a training program to bolster their qualifications for a role in the healthcare workforce, including the option of a formal caregiver position, supports the demand for such a program. Considering the need for healthcare workers to serve the growing elderly population and the desire of informal caregivers to find gainful employment, these informal caregivers could provide the impetus to invest in informal caregiver training. PMID:26782869

  13. The power to resist: the relationship between power, stigma, and negative symptoms in schizophrenia.

    Science.gov (United States)

    Campellone, Timothy R; Caponigro, Janelle M; Kring, Ann M

    2014-02-28

    Stigmatizing beliefs about mental illness can be a daily struggle for people with schizophrenia. While investigations into the impact of internalizing stigma on negative symptoms have yielded mixed results, resistance to stigmatizing beliefs has received little attention. In this study, we examined the linkage between internalized stigma, stigma resistance, negative symptoms, and social power, or perceived ability to influence others during social interactions among people with schizophrenia. Further, we sought to determine whether resistance to stigma would be bolstered by social power, with greater power in relationships with other possibly buffering against motivation/pleasure negative symptoms. Fifty-one people with schizophrenia or schizoaffective disorder completed measures of social power, internalized stigma, and stigma resistance. Negative symptoms were assessed using the Clinical Assessment Interview for Negative Symptoms (CAINS). Greater social power was associated with less internalized stigma and negative symptoms as well as more stigma resistance. Further, the relationship between social power and negative symptoms was partially mediated by stigma resistance. These findings provide evidence for the role of stigma resistance as a viable target for psychosocial interventions aimed at improving motivation and social power in people with schizophrenia.

  14. No evidence for melatonin-linked immunoenhancement over the annual cycle of an avian species.

    Science.gov (United States)

    Buehler, Deborah M; Koolhaas, Anita; Van't Hof, Thomas J; Schwabl, Ingrid; Dekinga, Anne; Piersma, Theunis; Tieleman, B Irene

    2009-05-01

    The winter immunoenhancement hypothesis associates long nights and increased exposure to melatonin with enhanced immune function in winter when resource availability is low and the chances of becoming ill are high. Thus, increased exposure to melatonin in the winter could be adaptive for species facing difficult winter conditions. This idea has found some support in studies of resident mammals. In birds, the link between day length and melatonin over the annual cycle is weaker, and contributions of melatonin to seasonal timing are unclear. Furthermore, many species, especially migrants, do not experience the most difficult conditions of their annual cycle in winter. In this study, we tested whether the winter immunoenhancement hypothesis holds in an avian species, the red knot Calidris canutus. We found that melatonin duration and amplitude varied significantly over the annual cycle with the highest values occurring in winter. However, peaks did not correspond to the winter solstice or with annual variation in immune function. Our findings do not support the winter immunoenhancement hypothesis in knots and question whether the idea that immune function should be bolstered in winter can be generalized to systems where winter is not the most difficult time of the year. PMID:19234709

  15. Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania.

    Science.gov (United States)

    Fox, Christopher B; Huynh, Chuong; O'Hara, Michael K; Onu, Adrian

    2013-03-15

    Many developing countries lack or have inadequate pandemic influenza vaccine manufacturing capacity. In the 2009 H1N1 pandemic, this led to delayed and inadequate vaccine coverage in the developing world. Thus, bolstering developing country influenza vaccine manufacturing capacity is urgently needed. The Cantacuzino Institute in Bucharest, Romania has been producing seasonal influenza vaccine since the 1970s, and has the capacity to produce ∼5 million doses of monovalent vaccine in the event of an influenza pandemic. Inclusion of an adjuvant in the vaccine could enable antigen dose sparing, expanding vaccine coverage and potentially allowing universal vaccination of the Romanian population and possibly neighboring countries. However, adjuvant formulation and manufacturing know-how are difficult to access. This manuscript describes the successful transfer of oil-in-water emulsion adjuvant manufacturing and quality control technologies from the Infectious Disease Research Institute in Seattle, USA to the Cantacuzino Institute. By describing the challenges and accomplishments of the project, it is hoped that the knowledge and experience gained will benefit other institutes involved in similar technology transfer projects designed to facilitate increased vaccine manufacturing capacity in developing countries.

  16. Constraining the last 7 billion years of galaxy evolution in semi-analytic models

    CERN Document Server

    Mutch, Simon J; Croton, Darren J

    2012-01-01

    We investigate the ability of the Croton et al. (2006) semi-analytic model to reproduce the evolution of observed galaxies across the final 7 billion years of cosmic history. Using Monte-Carlo Markov Chain techniques we explore the available parameter space to produce a model which attempts to achieve a statistically accurate fit to the observed stellar mass function at z=0 and z~0.8, as well as the local black hole-bulge relation. We find that in order to be successful we are required to push supernova feedback efficiencies to extreme limits which are, in some cases, unjustified by current observations. This leads us to the conclusion that the current model may be incomplete. Using the posterior probability distributions provided by our fitting, as well as the qualitative details of our produced stellar mass functions, we suggest that any future model improvements must act to preferentially bolster star formation efficiency in the most massive halos at high redshift.

  17. ASTEROSEISMOLOGY OF THE SOLAR ANALOGS 16 Cyg A AND B FROM KEPLER OBSERVATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Metcalfe, T. S.; Dogan, G. [High Altitude Observatory, NCAR, P.O. Box 3000, Boulder, CO 80307 (United States); Chaplin, W. J.; Garcia, R. A.; Basu, S.; Deheuvels, S.; Miglio, A. [Kavli Institute for Theoretical Physics, Kohn Hall, University of California, Santa Barbara, CA 93106 (United States); Appourchaux, T. [Institut d' Astrophysique Spatiale, Univ Paris-Sud, UMR8617, CNRS, Batiment 121, 91405 Orsay Cedex (France); Brandao, I. [Centro de Astrofisica and Faculdade de Ciencias, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Creevey, O. L.; Salabert, D. [Laboratoire Lagrange, UMR7293, Observatoire de la Cote d' Azur, Universite de Nice Sophia-Antipolis, CNRS, BP 4229, 06304 Nice Cedex 4 (France); Eggenberger, P. [Observatoire de Geneve, Universite de Geneve, 51 Ch. des Maillettes, CH-1290 Sauverny (Switzerland); Karoff, C. [Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Stello, D.; Benomar, O. [Sydney Institute for Astronomy (SIfA), School of Physics, University of Sydney, NSW 2006 (Australia); Y Latin-Small-Letter-Dotless-I ld Latin-Small-Letter-Dotless-I z, M.; Celik, Z. [Department of Astronomy and Space Sciences, Ege University, Bornova, 35100 Izmir (Turkey); Antia, H. M. [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400005 (India); Howe, R. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom); Regulo, C. [Instituto de Astrofisica de Canarias, 38205 La Laguna, Tenerife (Spain); and others

    2012-03-20

    The evolved solar-type stars 16 Cyg A and B have long been studied as solar analogs, yielding a glimpse into the future of our own Sun. The orbital period of the binary system is too long to provide meaningful dynamical constraints on the stellar properties, but asteroseismology can help because the stars are among the brightest in the Kepler field. We present an analysis of three months of nearly uninterrupted photometry of 16 Cyg A and B from the Kepler space telescope. We extract a total of 46 and 41 oscillation frequencies for the two components, respectively, including a clear detection of octupole (l = 3) modes in both stars. We derive the properties of each star independently using the Asteroseismic Modeling Portal, fitting the individual oscillation frequencies and other observational constraints simultaneously. We evaluate the systematic uncertainties from an ensemble of results generated by a variety of stellar evolution codes and fitting methods. The optimal models derived by fitting each component individually yield a common age (t = 6.8 {+-} 0.4 Gyr) and initial composition (Z{sub i} = 0.024 {+-} 0.002, Y{sub i} = 0.25 {+-} 0.01) within the uncertainties, as expected for the components of a binary system, bolstering our confidence in the reliability of asteroseismic techniques. The longer data sets that will ultimately become available will allow future studies of differential rotation, convection zone depths, and long-term changes due to stellar activity cycles.

  18. [Cognitive Function and Calcium. Ca2+-dependent regulatory mechanism of circadian clock oscillation and its relevance to neuronal function].

    Science.gov (United States)

    Kon, Naohiro; Fukada, Yoshitaka

    2015-02-01

    Circadian clock generates a variety of biological rhythms such as sleep/wake cycles and blood hormone rhythms. The circadian clock also bolsters daily mental activities. In fact, abnormalities of the circadian rhythms are found in several neurological disorders. The circadian clock has two important functions: (i) a cell-autonomous oscillatory function and (ii) a phase-adjusting function that synchronizes the clock oscillation with environmental cycling conditions such as light/dark cycle. Behavioral rhythms are controlled by the central clock in hypothalamic suprachiasmatic nucleus (SCN). The central clock orchestrates peripheral clocks in the other tissues via neuronal connection and/or actions of humoral factors. The molecular mechanism of the cell-autonomous clock is based on transcriptional feedback regulation of clock genes by their encoded products. Ca2+ is essential for not only the light response of the clock but also the cell autonomous oscillation mechanism. This article provides an overview of recent progress in studies of Ca2+-dependent regulatory mechanism of the molecular clockwork. PMID:25634045

  19. Report on the first Quadrennial Technology Review (QTR)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-09-30

    Access to clean, affordable, secure, and reliable energy has been a cornerstone of America’s economic growth. The Nation’s systems that produce, store, transmit, and use energy are falling short of U.S. needs. Maintaining energy security, bolstering U.S. competitiveness, and mitigating the environmental impacts of energy are long-­standing challenges. Governments, consumers, and the private sector have worked for decades to address these challenges, yet they remain among the Nation’s most pressing issues. President Obama has articulated broad national energy goals for reducing U.S. dependence on oil, reducing pollution, and investing in research and development (R&D) for clean-­energy technologies in the United States to create jobs. These include: Reducing oil imports by one-third by 2025; Supporting the deployment of 1 million electric vehicles on the road by 2015; Making non-residential buildings 20% more energy efficient by 2020; Deriving 80% of America's electricity from clean-energy sources by 2035; and Reducing greenhouse gas emissions by 175 by 2020 and 83% of 2050, from a 2005 baseline.

  20. Do Smallholder, Mixed Crop-Livestock Livelihoods Encourage Sustainable Agricultural Practices? A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Thomas K. Rudel

    2016-02-01

    Full Text Available As calls for bolstering ecosystem services from croplands have grown more insistent during the past two decades, the search for ways to foster these agriculture-sustaining services has become more urgent. In this context we examine by means of a meta-analysis the argument, proposed by Robert McC. Netting, that small-scale, mixed crop-livestock farming, a common livelihood among poor rural peoples, leads to environmentally sustainable agricultural practices. As predicted, mixed crop-livestock farms exhibit more sustainable practices, but, contrary to predictions, a small scale of operation does not predict sustainability. Many smallholders on mixed crop-livestock farms use sustainable practices, but other smallholders practice a degrading, input-scarce agriculture. Some large farm operators use soil-conserving, minimum-tillage techniques while other large operators ignore soil-conserving techniques and practice an industrialized, high chemical input agriculture. The strength and pervasiveness of the link in the data between mixed crop-livestock farming and sustainable agricultural practices argues for agricultural policies that promote mixed crop-livestock livelihoods.

  1. Musical experience shapes top-down auditory mechanisms: evidence from masking and auditory attention performance.

    Science.gov (United States)

    Strait, Dana L; Kraus, Nina; Parbery-Clark, Alexandra; Ashley, Richard

    2010-03-01

    A growing body of research suggests that cognitive functions, such as attention and memory, drive perception by tuning sensory mechanisms to relevant acoustic features. Long-term musical experience also modulates lower-level auditory function, although the mechanisms by which this occurs remain uncertain. In order to tease apart the mechanisms that drive perceptual enhancements in musicians, we posed the question: do well-developed cognitive abilities fine-tune auditory perception in a top-down fashion? We administered a standardized battery of perceptual and cognitive tests to adult musicians and non-musicians, including tasks either more or less susceptible to cognitive control (e.g., backward versus simultaneous masking) and more or less dependent on auditory or visual processing (e.g., auditory versus visual attention). Outcomes indicate lower perceptual thresholds in musicians specifically for auditory tasks that relate with cognitive abilities, such as backward masking and auditory attention. These enhancements were observed in the absence of group differences for the simultaneous masking and visual attention tasks. Our results suggest that long-term musical practice strengthens cognitive functions and that these functions benefit auditory skills. Musical training bolsters higher-level mechanisms that, when impaired, relate to language and literacy deficits. Thus, musical training may serve to lessen the impact of these deficits by strengthening the corticofugal system for hearing. PMID:20018234

  2. Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

    International Nuclear Information System (INIS)

    Chemotherapy has been a mainstay in cancer treatment for many years. Despite some success, the cure rate with chemotherapy remains unsatisfactory in some types of cancers, and severe side effects from these treatments are a concern. Recently, understanding of the dynamic interplay between the tumor and immune system has led to the development of novel immunotherapies, including cancer vaccines. Cancer vaccines have many advantageous features, but their use has been hampered by poor immunogenicity. Many developments have increased their potency in pre-clinical models, but cancer vaccines continue to have a poor clinical track record. In part, this could be due to an inability to effectively overcome tumor-induced immune suppression. It had been generally assumed that immune-stimulatory cancer vaccines could not be used in combination with immunosuppressive chemotherapies, but recent evidence has challenged this dogma. Chemotherapies could be used to condition the immune system and tumor to create an environment where cancer vaccines have a better chance of success. Other types of immunotherapies could also be used to modulate the immune system. This review will discuss how immune modulation by chemotherapy or immunotherapy could be used to bolster the effects of cancer vaccines and discuss the advantages and disadvantages of these treatments

  3. Longitudinal Impact of Two Universal Preventive Interventions in First Grade on Educational Outcomes in High School.

    Science.gov (United States)

    Bradshaw, Catherine P; Zmuda, Jessika H; Kellam, Sheppard G; Ialongo, Nicholas S

    2009-11-01

    This study examined the longitudinal effects of 2 first-grade universal preventive interventions on academic outcomes (e.g., achievement, special education service use, graduation, postsecondary education) through age 19 in a sample of 678 urban, primarily African American children. The classroom-centered intervention combined the Good Behavior Game (H. H. Barrish, Saunders, & Wolfe, 1969) with an enhanced academic curriculum, whereas a second intervention, the Family-School Partnership, focused on promoting parental involvement in educational activities and bolstering parents' behavior management strategies. Both programs aimed to address the proximal targets of aggressive behavior and poor academic achievement. Although the effects varied by gender, the classroom-centered intervention was associated with higher scores on standardized achievement tests, greater odds of high school graduation and college attendance, and reduced odds of special education service use. The intervention effects of the Family-School Partnership were in the expected direction; however, only 1 effect reached statistical significance. The findings of this randomized controlled trial illustrate the long-term educational impact of preventive interventions in early elementary school. PMID:23766545

  4. "I used to be an ordinary mom": The maternal identity of mothers of women abused by an intimate partner.

    Science.gov (United States)

    Gueta, Keren; Peled, Einat; Sander-Almoznino, Nili

    2016-01-01

    Mothers of children who suffer various problems tend to discuss their experience as a crisis in their maternal identity, regardless of whether the children are young or adults. However, the maternal identity of mothers who are aware that their adult daughters are being abused has not yet been explored. This study aims to examine the construction of the maternal identity by Israeli women whose grown daughters have been subjected to intimate partner violence (IPV), in the light of cultural representations of motherhood and domestic violence (DV). Thematic discourse analysis of in-depth interviews with 11 mothers identified discursive strategies that they used to negotiate a troubled maternal identity following their daughters' IPV experience. The mothers asserted a positive maternal identity by referring to common discourses about DV and motherhood, in a bid to bolster their "good mother" identity, to reframe motherhood, and to assign responsibility for the abuse to the abuser, to their daughters, or to the patriarchal social structure. The implications of these findings for motherhood and maternal identity theories and for professionals working in the field of DV are discussed. (PsycINFO Database Record PMID:26752440

  5. The Relationship of Self Esteem and Humor Styles in First Class Medical Students: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Soner Cakmak

    2015-12-01

    Material and Methods: Two hundred three medical students (107 males, 96 females were included this study. Self-esteem was measured with the Rosenberg Self Esteem Scale and humor style was measured with Humor Styles Questionnaire. Results: The rate of students who have mild or high self-esteem levels was 89.7%. In Humor Styles Questionnaire, the average scores of affiliative and self-enhancing humor were significantly higher than the average scores of aggressive and self-defeating humor. Male students were using humor, especially aggressive and self-defeating humor styles more commonly than female students. A positive correlation was found between self-esteem and affiliative and self-enhancing humor styles. Conclusion: The present study revealed a positive correlation between self-esteem and positive humor styles. There is a need to develop educational models that would bolster self-esteem and positive humor in medical students. [Cukurova Med J 2015; 40(4.000: 782-793

  6. The next frontier in composite tissue allotransplantation.

    Science.gov (United States)

    Ren, Xiaoping; Laugel, Michael C

    2013-01-01

    Solid organ transplantations became a clinical option in the 1950s. The hand allograft was the pioneer of composite tissue allotransplantation (CTA), successfully started near the end of the last century despite arguments over the practicality and methods. Since then, CTA such as hand and face has continued to progress from the theoretical to clinical reality. The treatment principles, drug combinations, and mechanisms of the immunosuppression medications on which contemporary transplant surgeries have been based continue to develop as researchers and physicians gain more experience in the CTA field. It could be argued that the ethical issues associated with CTA have prevented evolution of the field rather than surgical or technical skill. This is particularly true for allo-head and body reconstruction (AHBR). How can leaders in the field of CTA develop a model that would satisfy ethical concerns? Bolstered by recent successes in the field, is it time to traverse the next frontier? Can AHBR ever be a feasible option in the clinical setting? The reader will be provided with a brief history of CTA from theory to research to clinical practice. A concise description of AHBR as it pertains to the critical procedure (i.e., surgery design) will also be discussed. PMID:23157698

  7. Portugal: participation in peace missions as a factor of external credibility

    Directory of Open Access Journals (Sweden)

    Maria do Céu Pinto

    2012-01-01

    Full Text Available In per capita terms, Portugal is one of the most significant European contributors to international peacekeeping operations around the world. It presently ranks 45th in a list of 115 countries contributing to the United Nations (UN peace operations and 7th in the European Union (EU. The multiplicity of forces used, as well as the diversity of the locations of deployment, reflect the ambition and effort made by the Portuguese governments in the last 20 years. Portuguese participation in peacekeeping missions has been seen as a vehicle for strengthening Portugal’s position in the world: the involvement under the flag of international organisations raises the profile of Portuguese foreign policy and diplomacy. In this paper, we argue that Portuguese involvement in peace missions reflects Portugal’s pursuit of its national interest and foreign policy. The aim is to bolster Portugal’s capacity to influence the decision-making process in major international fora, such as the UN, NATO and the EU. The goal established since the late 1980s aims to strengthen the visibility and specific weight of Portugal in the multilateral framework. The country´s contribution to peacekeeping operations has increased the bargaining power of Portugal, which has become an active partner with a more audible voice within those organisations. That voice led to gaining a better position when it came to negotiating major international posts and policies.

  8. The Effects of Triggers’ Modifying on Adolescent Self-Efficacy with Asthma: A Randomized Controlled Clinical Trial

    Directory of Open Access Journals (Sweden)

    Leila Valizadeh

    2014-06-01

    Full Text Available Introduction: The management of asthma during adolescence has specific challenges and is likely influenced, to some extent, by the patient's belief in their ability to affect change, their self-efficacy. Bolstering self-efficacy could potentially improve an adolescent’s ability to self-manage their asthma. The aim of this study was to examine the effects of a triggers’ educational-modifying intervention on self-efficacy among adolescents diagnosed with asthma living in Iran. Methods: Sixty adolescents, aged 12 to 18 years, diagnosed with asthma participated in this randomized clinical trial. Participants randomly assigned to the control group received standard care while those assigned to the experimental group participated in a 5 week, nurse led, triggers modifying educational intervention in specialized clinics of lung in Tabriz, Iran. The self-efficacy scale developed by Bursh et al., was used for data collection. Results: The level of self- efficacy in two groups before intervention was not statistically significant, while the post intervention measures were statistically significant. Intervention was effective in improving adolescents’ self-efficacy. Conclusion: Since this type of intervention has the potential to improve Self- efficacy in adolescents with asthma, it is suggested that adolescence directly education about asthma triggers along with modulating triggers will be of value and parent‐centered could be diminished. The need for such interventions emphasizes in clinic and outpatient clinics.

  9. When two heads are better than one: Interactive versus independent benefits of collaborative cognition.

    Science.gov (United States)

    Brennan, Allison A; Enns, James T

    2015-08-01

    Previous research has shown that two heads working together can outperform one working alone, but whether such benefits result from social interaction or from the statistical facilitation of independent responses is not clear. Here we apply Miller's (Cognitive Psychology, 14, 247-279, 1982; Ulrich, Miller & Schröter, Behavior Research Methods, 39(2), 291-302, 2007) race model inequality (RMI) to distinguish between these two possibilities. Pairs of participants completed a visual enumeration task, both as independent individuals and as two members of a team. The results showed that team performance exceeded the efficiency of two individuals working independently, indicating that interpersonal interaction underlies the collaborative gains in this task. This interpretation was bolstered by analyses showing that the magnitude of the collaborative benefit was positively mediated by the strength of social affiliation and by the similarity of verbal communication among team members. This research serves as a proof-of-concept that Miller's RMI can differentiate between interactive versus independent effects of collaborative cognition. Moreover, the finding that social affiliation and communication similarity each contribute to the collaborative benefit suggests new avenues of research for establishing the mechanisms supporting collaborative cognition. PMID:25416077

  10. A need analysis of technical writing skill of engineering students in India

    Directory of Open Access Journals (Sweden)

    Evangeline JCK

    2016-01-01

    Full Text Available The development of Science and Technology has bolstered the use of English Language around the world. The purpose of teaching English to non-native speakers of English is to help them in communicating, and more precisely sharing knowledge and information with speakers of other languages. In the field of higher education, the learners need English for Academic purposes (EAP and learn to use it later for occupational purposes (EOP. Students who had their primary education in English, manage to cope up with this way of the world; whereas students from sub-standard schools or vernacular medium of instruction, many times find it very difficult to cope up with the trend. This paper analyses the need to teach technical writing as a course to students of technical education in order to make them competent in academics and later in their work place. A few sample technical writing papers have been assessed and added to substantiate the need for educating students in technical writing skill. A review of literature and available ESP courses have been done to analyse the present strategies in teaching writing. A course was designed and tried to improve technical writing skill of students of higher education.

  11. EVA Skills Training

    Science.gov (United States)

    Parazynski, Scott

    2012-01-01

    Dr. Parazynski and a colleague from Extravehicular Activity (EVA), Robotics, & Crew Systems Operations (DX) worked closely to build the EVA Skills Training Program, and for the first time, defined the gold standards of EVA performance, allowing crewmembers to increase their performance significantly. As part of the program, individuals had the opportunity to learn at their own rate, taking additional water time as required, to achieve that level of performance. This focus on training to one's strengths and weaknesses to bolster them enabled the Crew Office and DX to field a much larger group of spacewalkers for the daunting "wall of EVA" required for the building and maintenance of the ISS. Parazynski also stressed the need for designers to understand the capabilities and the limitations of a human in a spacesuit, as well as opportunities to improve future generations of space. He shared lessons learned (how the Crew Office engaged in these endeavors) and illustrated the need to work as a team to develop these complex systems.

  12. Conductometric and volumetric studies of atorvastatin in aqueous solution of arginine from 298.15 to 313.15 K

    Directory of Open Access Journals (Sweden)

    M. M. R. Meor Mohd Affandi

    2016-01-01

    Full Text Available Categorized as a Biopharmaceutics Classification System Class II drugs, atorvastatin (ATV exhibits low aqueous solubility and bioavailability thus presenting an obstacle and great challenge to formulation researchers. Numerous studies are available in regard to the solubility enhancement of ATV, but very few actually describe this phenomenon in terms of thermodynamics and the solute-solvent interaction. Arginine (ARG is an amino acid that has been reported to enhance the solubility of the highly insoluble wheat protein gluten through hydrogen bonding and π electron-cation interaction. To our knowledge, ARG has never been investigated as a solubility enhancement agent of aqueous insoluble drugs. Thus, this study aimed to elucidate the solute-solvent and solute-cosolute interactions and derive thermodynamic parameters that bolstered the solubility of ATV in the presence of ARG. We examined the electrolytic conductance and densities of ATV-ARG binary system covering the temperature ranging from 298.15 K to 313.15 K. Conductometric and volumetric parameters such as limiting molar conductance, association constants, limiting partial molar volumes, and expansibility values were calculated. Additionally, thermodynamic parameters (ΔG0, ΔH0, ΔS0, and Es involved in the association process of the solute in the aqueous solution of ARG were also determined.

  13. Coral Bleaching Susceptibility Is Decreased following Short-Term (1–3 Year Prior Temperature Exposure and Evolutionary History

    Directory of Open Access Journals (Sweden)

    Joshua A. Haslun

    2011-01-01

    Full Text Available Coral exposed to short periods of temperature stress (≥1.0°C above mean monthly maximum and/or increased frequencies of high temperatures may bolster resilience to global warming associated with climate change. We compared Montastraea cavernosa (Linnaeus, 1767; Cnidaria, Scleractinia, Faviidae from the Florida Keys National Marine Sanctuary (FKNMS and the Flower Garden Banks National Marine Sanctuary (FGBNMS. Thermal stress has been reported frequently within the FKNMS; however, corals in the FGBNMS experience nominal exposures to similar stressors. Corals were exposed to three temperatures (27°C, 31°C, and 35°C for 72 h. Colonies from the FKNMS lost significantly fewer viable and necrotic zooxanthellae under conditions of acute stress (35°C than the FGBNMS colonies. This indicates that the FKNMS corals are less temperature-sensitive than those in the FGBNMS. The observed differences point to greater prior temperature exposure and adaptation in the former versus the latter site when correlated to previous years of thermal exposure.

  14. A legal "right" to mental health care? Impediments to a global vision of mental health care access.

    Science.gov (United States)

    Glover-Thomas, N; Chima, S C

    2015-12-01

    Mental health law across many jurisdictions provides a legal framework for the compulsory detention and, where appropriate, treatment in hospital of people with mental health problems. Latent within many of these "systems" of mental health provision is the concern that the quality of care people receive does not always meet legal and ethical norms. For many, there remains the very serious recognition that access to mental health care in its entirety remains elusive. International human rights discourse has influenced the shaping of modern mental health laws in many developed countries. In 2008, the Convention on the Rights of Persons with Disabilities (CRPD) entered into force. For many countries, such as South Africa, the CRPD provides a human rights instrument with the scope to establish a worldwide means of bolstering human rights. This paper examines both the UK and the broader African position with regard to the extent redress can be sought if and when an individual does not receive the care and treatment needed. Within this, consideration will be given to one of the paradoxes of mental health care which bedevil mental health systems: How do legal frameworks for detaining and treating people without their consent work when there is no corresponding enforceable right that appropriate treatment or suitable conditions of detention must be provided. The focus of this paper is the question of whether there is indeed a legal "right" to mental health care.

  15. Radiochemistry Education and Research Program at the Pennsylvania State University

    Science.gov (United States)

    Ünlü, Kenan

    2009-08-01

    A new Radiochemistry Education and Research Program was started at the Pennsylvania University, Radiation Science and Engineering Center. The program was initially supported by the Department of Energy, Radiochemistry Education Award Program (REAP). Using REAP funding as leverage we obtained support from the Los Alamos National Laboratory, Department of Homeland Security, Domestic Nuclear Detection Office, various internal funding from PSU and other entities. The PSU radiochemistry program primarily addresses radiochemistry education and secondarily nuclear and radiochemistry research. The education program consists of bolstering our existing radiochemistry and related courses; Nuclear and Radiochemistry, Radiation Detection and Measurement, Radiological Safety and developing new courses, e.g., Laboratory Experiments in Applied Nuclear and Radiochemistry, and Nuclear Methods in Science. A new laboratory has been created with state of the art equipment for the Laboratory Experiments in Applied Nuclear and Radiochemistry course. We also plan to revitalize the nuclear and radiochemistry research programs. We established a state-of-the-art Neutron Activation Analysis Laboratory and a gamma ray spectroscopy laboratory that has 10 stations including state-of-the-art nuclear spectroscopy hardware and software. In addition, we embarked on an expansion plan that included building a new neutron beam hall and neutron beam ports with a cold neutron source. One of the reasons to have a cold neutron source is for the development of a prompt gamma activation analysis facility. A detailed description of PSU radiochemistry education and research program will be given and the future plans will be discussed.

  16. 中国传统文化元素在服装设计中的创新性应用%The Innovative Application of Chinese Traditional Cultural Elements in Fashion Design

    Institute of Scientific and Technical Information of China (English)

    焦乐杰

    2013-01-01

    Chinese colorful traditional cultural elements have become China ’ s national costume designers ’ bolster for brands building and showcase of the Chinese clothing culture art .But in the process of artistic creation ,there ex-ist quite a lot of problems like tradition neglecting ,lack of innovation ,admiring the foreign styles and so on .Thus, the contemporary fashion designers must take the initiative to learn Chinese excellent traditional cultural enrich -ment,so that to make the Chinese traditional costumes glow with unique artistic charm .%我国丰富多彩的传统文化已经成为服装设计师打造民族服装品牌和展示中国服装文化艺术的重要元素。但是我国服装设计师在运用传统文化元素进行艺术创作的过程中仍然存在着忽视传统、崇洋媚外,机械复古、缺乏创新等问题。因此,服装设计师必须将中国传统文化元素融入服装设计中,从而使中国传统服装焕发出独特的艺术魅力。

  17. Exploiting dimensionality and defect mitigation to create tunable microwave dielectrics.

    Science.gov (United States)

    Lee, Che-Hui; Orloff, Nathan D; Birol, Turan; Zhu, Ye; Goian, Veronica; Rocas, Eduard; Haislmaier, Ryan; Vlahos, Eftihia; Mundy, Julia A; Kourkoutis, Lena F; Nie, Yuefeng; Biegalski, Michael D; Zhang, Jingshu; Bernhagen, Margitta; Benedek, Nicole A; Kim, Yongsam; Brock, Joel D; Uecker, Reinhard; Xi, X X; Gopalan, Venkatraman; Nuzhnyy, Dmitry; Kamba, Stanislav; Muller, David A; Takeuchi, Ichiro; Booth, James C; Fennie, Craig J; Schlom, Darrell G

    2013-10-24

    The miniaturization and integration of frequency-agile microwave circuits--relevant to electronically tunable filters, antennas, resonators and phase shifters--with microelectronics offers tantalizing device possibilities, yet requires thin films whose dielectric constant at gigahertz frequencies can be tuned by applying a quasi-static electric field. Appropriate systems such as BaxSr1-xTiO3 have a paraelectric-ferroelectric transition just below ambient temperature, providing high tunability. Unfortunately, such films suffer significant losses arising from defects. Recognizing that progress is stymied by dielectric loss, we start with a system with exceptionally low loss--Srn+1TinO3n+1 phases--in which (SrO)2 crystallographic shear planes provide an alternative to the formation of point defects for accommodating non-stoichiometry. Here we report the experimental realization of a highly tunable ground state arising from the emergence of a local ferroelectric instability in biaxially strained Srn+1TinO3n+1 phases with n ≥ 3 at frequencies up to 125 GHz. In contrast to traditional methods of modifying ferroelectrics-doping or strain-in this unique system an increase in the separation between the (SrO)2 planes, which can be achieved by changing n, bolsters the local ferroelectric instability. This new control parameter, n, can be exploited to achieve a figure of merit at room temperature that rivals all known tunable microwave dielectrics. PMID:24132232

  18. Playing Music for a Smarter Ear: Cognitive, Perceptual and Neurobiological Evidence.

    Science.gov (United States)

    Strait, Dana; Kraus, Nina

    2011-12-01

    Human hearing depends on a combination of cognitive and sensory processes that function by means of an interactive circuitry of bottom-up and top-down neural pathways, extending from the cochlea to the cortex and back again. Given that similar neural pathways are recruited to process sounds related to both music and language, it is not surprising that the auditory expertise gained over years of consistent music practice fine-tunes the human auditory system in a comprehensive fashion, strengthening neurobiological and cognitive underpinnings of both music and speech processing. In this review we argue not only that common neural mechanisms for speech and music exist, but that experience in music leads to enhancements in sensory and cognitive contributors to speech processing. Of specific interest is the potential for music training to bolster neural mechanisms that undergird language-related skills, such as reading and hearing speech in background noise, which are critical to academic progress, emotional health, and vocational success. PMID:22993456

  19. In Search of the jüdische Typus: A Proposed Benchmark to Test the Genetic Basis of Jewishness Challenges Notions of "Jewish Biomarkers".

    Science.gov (United States)

    Elhaik, Eran

    2016-01-01

    The debate as to whether Jewishness is a biological trait inherent from an "authentic" "Jewish type" (jüdische Typus) ancestor or a system of beliefs has been raging for over two centuries. While the accumulated biological and anthropological evidence support the latter argument, recent genetic findings, bolstered by the direct-to-consumer genetic industry, purport to identify Jews or quantify one's Jewishness from genomic data. To test the merit of claims that Jews and non-Jews are genetically distinguishable, we propose a benchmark where genomic data of Jews and non-Jews are hybridized over two generations and the observed and predicted Jewishness of the terminal offspring according to either the Orthodox religious law (Halacha) or the Israeli Law of Return are compared. Members of academia, the public, and 23andMe were invited to use the benchmark to test claims that Jews are genetically distinct from non-Jews. Here, we report the findings from these trials. We also compare the genomic similarity of ∼300 individuals from nearly thirty Afro-Eurasian Jewish communities to a simulated jüdische Typus population. The results are discussed in light of modern trends in the genetics of Jews and related fields and provide a tentative answer to the ageless question "who is a Jew?" PMID:27547215

  20. Opening new horizons, building new synergies : 1998 annual report of Hydro-Quebec International

    International Nuclear Information System (INIS)

    Hydro-Quebec International (HQI) was established in 1978 as a wholly owned subsidiary of Hydro-Quebec. Its mission is to contribute to Hydro-Quebec's growth and profitability by investing in energy partnerships and by selling Hydro-Quebec expertise internationally. This annual report presents highlights of the company's operations, balance sheet, financial position, and investments. 1998 proved to be a year of market development and prospecting which yielded promising results. The expanded scope of the company that now includes investment and infrastructure construction was already generating $ 26 million in economic spinoff for Quebec. The report highlights HQI's involvement in Europe, the Middle East, Africa, and Asia. Great strides have been made also in ensuring the most rigorous practices possible to assess and manage risk and to bolster the company's ability to take unforeseen events in stride. On the investment side, in 1998, the first year of its involvement as an investor, HQI initiated investments amounting to $137 million. Plans are to double that figure in 1999. tabs., figs

  1. Toward ubiquitous environmental gas sensors-capitalizing on the promise of graphene.

    Science.gov (United States)

    Ratinac, Kyle R; Yang, Wenrong; Ringer, Simon P; Braet, Filip

    2010-02-15

    Atomically thin sheets of carbon known as "graphene" have captured the imagination of much of the scientific world during the past few years. Although these single sheets of graphite were under our noses for years-within technologies ranging from the humble pencil, which has been around since at least 1565 (Petroski, H. The Pencil: A History of Design and Circumstance; Alfred A. Knopf: New York, 1993), to modern nuclear reactors-graphene was merely considered as part of graphite's crystal structure until 2004, when Novoselov, Geim, and colleagues (Science 2004, 306, 666-669) first presented some of the surprising electrical properties of graphene layers they had isolated by mechanically peeling sheets off graphite crystals. Today, graphene's unique electronic structures and properties, bolstered by other intriguing properties discovered in the intervening years, threaten the dominance of carbon nanotubes, a more mature allotrope of carbon, in potential applications from electronics to sensors. In this review, we will consider the promise of graphene for producing small-scale gas sensors for environmental monitoring.

  2. Peru Water Resources: Integrating NASA Earth Observations into Water Resource Planning and Management in Perus La Libertad Region

    Science.gov (United States)

    Padgett-Vasquez, Steve; Steentofte, Catherine; Holbrook, Abigail

    2014-01-01

    Developing countries often struggle with providing water security and sanitation services to their populations. An important aspect of improving security and sanitation is developing a comprehensive understanding of the country's water budget. Water For People, a non-profit organization dedicated to providing clean drinking water, is working with the Peruvian government to develop a water budget for the La Libertad region of Peru which includes the creation of an extensive watershed management plan. Currently, the data archive of the necessary variables to create the water management plan is extremely limited. Implementing NASA Earth observations has bolstered the dataset being used by Water For People, and the METRIC (Mapping EvapoTranspiration at High Resolution and Internalized Calibration) model has allowed for the estimation of the evapotranspiration values for the region. Landsat 8 imagery and the DEM (Digital Elevation Model) from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) sensor onboard Terra were used to derive the land cover information, and were used in conjunction with local weather data of Cascas from Peru's National Meteorological and Hydrological Service (SENAMHI). Python was used to combine input variables and METRIC model calculations to approximate the evapotranspiration values for the Ochape sub-basin of the Chicama River watershed. Once calculated, the evapotranspiration values and methodology were shared Water For People to help supplement their decision support tools in the La Libertad region of Peru and potentially apply the methodology in other areas of need.

  3. Migration selection, protection, and acculturation in health: a binational perspective on older adults.

    Science.gov (United States)

    Riosmena, Fernando; Wong, Rebeca; Palloni, Alberto

    2013-06-01

    In this article, we test for four potential explanations of the Hispanic Health Paradox (HHP): the "salmon bias," emigration selection, and sociocultural protection originating in either destination or sending country. To reduce biases related to attrition by return migration typical of most U.S.-based surveys, we combine data from the Mexican Health and Aging Study in Mexico and the U.S. National Health Interview Survey to compare self-reported diabetes, hypertension, current smoking, obesity, and self-rated health among Mexican-born men ages 50 and older according to their previous U.S. migration experience, and U.S.-born Mexican Americans and non-Hispanic whites. We also use height, a measure of health during childhood, to bolster some of our tests. We find an immigrant advantage relative to non-Hispanic whites in hypertension and, to a lesser extent, obesity. We find evidence consistent with emigration selection and the salmon bias in height, hypertension, and self-rated health among immigrants with less than 15 years of experience in the United States; we do not find conclusive evidence consistent with sociocultural protection mechanisms. Finally, we illustrate that although ignoring return migrants when testing for the HHP and its mechanisms, as well as for the association between U.S. experience and health, exaggerates these associations, they are not fully driven by return migration-related attrition.

  4. Patterns and biases in climate change research on amphibians and reptiles: a systematic review

    Science.gov (United States)

    2016-01-01

    Climate change probably has severe impacts on animal populations, but demonstrating a causal link can be difficult because of potential influences by additional factors. Assessing global impacts of climate change effects may also be hampered by narrow taxonomic and geographical research foci. We review studies on the effects of climate change on populations of amphibians and reptiles to assess climate change effects and potential biases associated with the body of work that has been conducted within the last decade. We use data from 104 studies regarding the effect of climate on 313 species, from 464 species–study combinations. Climate change effects were reported in 65% of studies. Climate change was identified as causing population declines or range restrictions in half of the cases. The probability of identifying an effect of climate change varied among regions, taxa and research methods. Climatic effects were equally prevalent in studies exclusively investigating climate factors (more than 50% of studies) and in studies including additional factors, thus bolstering confidence in the results of studies exclusively examining effects of climate change. Our analyses reveal biases with respect to geography, taxonomy and research question, making global conclusions impossible. Additional research should focus on under-represented regions, taxa and questions. Conservation and climate policy should consider the documented harm climate change causes reptiles and amphibians.

  5. The chronic leukaemias

    Directory of Open Access Journals (Sweden)

    Peter Jacobs

    1989-09-01

    Full Text Available The slow progression of both chronic granulocytic and lymphocytic leukaemia, when compared to their acute counterparts, has been used as an argument to support less aggressive therapy or even, in some instances, a watch-and-wait policy. This conservative approach is bolstered by a number of observations including the ease with which haematologic control can initially be achieved, the older age of patients with the lymphocytic variant and the paucity of controlled data showing that long disease-free survival or cure can result from the use of aggressive treatment. Given these circumstances, it is not surprising that many such individuals are managed outside specialised centres using a variety of agents and schedules, both of which may, on occasions, be inappropriate. Accumulating evidence suggests a need to reconsider these practices since cure is now possible in selected patients with chronic granulocytic leukaemia while the use of multi-drug regimens in the lymphatic form can significantly improve survival. These advances are the result of carefully conducted clinical trials involving many individuals the world over and constitute the basis fo r advocating early referral to those institutions where all the necessary expertise is available.

  6. When what you have is who you are: self-uncertainty leads individualists to see themselves in their possessions.

    Science.gov (United States)

    Morrison, Kimberly Rios; Johnson, Camille S

    2011-05-01

    Four studies tested whether uncertainty about the self-concept can motivate people, particularly individualists who define themselves in terms of their personal traits and characteristics, to perceive their material possessions as extensions of themselves (i.e., as self-expressive). In Study 1, European American participants rated their favorite pair of blue jeans as more self-expressive after being induced to feel self-uncertain, whereas Asian American participants did not. In Study 2, participants who scored high on a measure of individualism rated their cars as more self-expressive following a self-uncertainty manipulation. In Study 3, individualists (but not collectivists) rated their favorite possessions as more self-expressive after being subject to self-uncertainty; a manipulation of self-irrelevant uncertainty did not produce these results. In Study 4, thinking about a self-expressive (relative to utilitarian) possession bolstered self-certainty among individualists, but not collectivists. Implications for research on culture, the self-concept, and possessions are discussed.

  7. Moving forward responsibly: Oversight for the nanotechnology-biology interface

    International Nuclear Information System (INIS)

    Challenges and opportunities for appropriate oversight of nanotechnology applied to or derived from biological systems (nano-bio interface) were discussed in a public workshop and dialog hosted by the Center for Science, Technology, and Public Policy of the University of Minnesota on September 15, 2005. This paper discusses the themes that emerged from the workshop, including the importance of analyzing potential gaps in current regulatory systems; deciding upon the general approach taken toward regulation; employing non-regulatory mechanisms for governance; making risk and other studies transparent and available to the public; bolstering mechanisms for public participation in risk analysis; creating more opportunities for meaningful discussion of the social and ethical dimensions of the nano-bio interface; increasing funds for implications and problem-solving research in this area; and having independent and reliable sources for communication. The workshop was successful in identifying ways of moving forward responsibly so that ultimately nanotechnology and its products can succeed in developers', researchers', regulators', and the public's eyes

  8. Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes

    Science.gov (United States)

    Jhala, Gaurang; Chee, Jonathan; Trivedi, Prerak M.; Selck, Claudia; Gurzov, Esteban N.; Graham, Kate L.; Thomas, Helen E.; Kay, Thomas W.H.; Krishnamurthy, Balasubramanian

    2016-01-01

    High-affinity self-reactive thymocytes are purged in the thymus, and residual self-reactive T cells, which are detectable in healthy subjects, are controlled by peripheral tolerance mechanisms. Breakdown in these mechanisms results in autoimmune disease, but antigen-specific therapy to augment natural mechanisms can prevent this. We aimed to determine when antigen-specific therapy is most effective. Islet autoantigens, proinsulin (PI), and islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) were expressed in the antigen-presenting cells (APCs) of autoimmune diabetes-prone nonobese diabetic (NOD) mice in a temporally controlled manner. PI expression from gestation until weaning was sufficient to completely protect NOD mice from diabetes, insulitis, and development of insulin autoantibodies. Insulin-specific T cells were significantly diminished, were naive, and did not express IFN-γ when challenged. This long-lasting effect from a brief period of treatment suggests that autoreactive T cells are not produced subsequently. We tracked IGRP206–214-specific CD8+ T cells in NOD mice expressing IGRP in APCs. When IGRP was expressed only until weaning, IGRP206–214-specific CD8+ T cells were not detected later in life. Thus, anti-islet autoimmunity is determined during early life, and autoreactive T cells are not generated in later life. Bolstering tolerance to islet antigens in the perinatal period is sufficient to impart lasting protection from diabetes.

  9. An Unattended Cloud-Profiling Radar for Use in Climate Research.

    Science.gov (United States)

    Moran, Kenneth P.; Martner, Brooks E.; Post, M. J.; Kropfli, Robert A.; Welsh, David C.; Widener, Kevin B.

    1998-03-01

    A new millimeter-wave cloud radar (MMCR) has been designed to provide detailed, long-term observations of nonprecipitating and weakly precipitating clouds at Cloud and Radiation Testbed (CART) sites of the Department of Energy's Atmospheric Radiation Measurement (ARM) program. Scientific requirements included excellent sensitivity and vertical resolution to detect weak and thin multiple layers of ice and liquid water clouds over the sites and long-term, unattended operations in remote locales. In response to these requirements, the innovative radar design features a vertically pointing, single-polarization, Doppler system operating at 35 GHz (Ka band). It uses a low-peak-power transmitter for long-term reliability and high-gain antenna and pulse-compressed waveforms to maximize sensitivity and resolution. The radar uses the same kind of signal processor as that used in commercial wind profilers. The first MMCR began operations at the CART in northern Oklahoma in late 1996 and has operated continuously there for thousands of hours. It routinely provides remarkably detailed images of the ever-changing cloud structure and kinematics over this densely instrumented site. Examples of the data are presented. The radar measurements will greatly improve quantitative documentation of cloud conditions over the CART sites and will bolster ARM research to understand how clouds impact climate through their effects on radiative transfer. Millimeter-wave radars such as the MMCR also have potential applications in the fields of aviation weather, weather modification, and basic cloud physics research.

  10. Brief intervention to encourage empathic discipline cuts suspension rates in half among adolescents.

    Science.gov (United States)

    Okonofua, Jason A; Paunesku, David; Walton, Gregory M

    2016-05-10

    Growing suspension rates predict major negative life outcomes, including adult incarceration and unemployment. Experiment 1 tested whether teachers (n = 39) could be encouraged to adopt an empathic rather than punitive mindset about discipline-to value students' perspectives and sustain positive relationships while encouraging better behavior. Experiment 2 tested whether an empathic response to misbehavior would sustain students' (n = 302) respect for teachers and motivation to behave well in class. These hypotheses were confirmed. Finally, a randomized field experiment tested a brief, online intervention to encourage teachers to adopt an empathic mindset about discipline. Evaluated at five middle schools in three districts (Nteachers = 31; Nstudents = 1,682), this intervention halved year-long student suspension rates from 9.6% to 4.8%. It also bolstered respect the most at-risk students, previously suspended students, perceived from teachers. Teachers' mindsets about discipline directly affect the quality of teacher-student relationships and student suspensions and, moreover, can be changed through scalable intervention. PMID:27114516

  11. The evolution of the federal funding policies for the public health surveillance component of Brazil's Unified Health System (SUS

    Directory of Open Access Journals (Sweden)

    Vitor Laerte Pinto Junior

    2014-12-01

    Full Text Available Health surveillance (HS is one of the key components of the Brazilian Unified Health System (SUS. This article describes recent changes in health surveillance funding models and the role these changes have had in the reorganization and decentralization of health actions. Federal law no. 8.080 of 1990 defined health surveillance as a fundamental pillar of the SUS, and an exclusive fund with equitable distribution criteria was created in the Basic Operational Norm of 1996 to pay for health surveillance actions. This step facilitated the decentralization of health care at the municipal level, giving local authorities autonomy to plan and provide services. The Health Pact of 2006 and its regulation under federal decree No. 3252 in 2009 bolstered the processes of decentralization, regionalization and integration of health care. Further changes in the basic concepts of health surveillance around the world and in the funding policies negotiated by different spheres of government in Brazil have been catalysts for the process of HS institutionalization in recent years.

  12. US firms still restructuring, cutting costs under oil price uncertainty

    International Nuclear Information System (INIS)

    Despite more than a decade of downsizing, continuing uncertainty in oil markets is forcing US petroleum companies into another round of cutting and restructuring operations. Wellhead gas prices in the US, although still volatile, in the past 2 years have risen to levels adequate to allow profits for most producers in that sector. Higher gas reserves valuations have strengthened producers' overall balance sheets. But the slide in oil prices from the middle of fourth quarter 1993 until the recent upswing the past month has withered producers' financial performances and reserves values. With little prospect of significantly higher oil prices anytime soon, US companies feel they have little choice but to continue pressing cost cutting moves in order to sustain profits in the near term while at the same time earnings a higher return on investment in the long term. Petroleum company executives are overlooking almost no operating or investment strategy thought capable of bolstering the bottom line. Because no two US oil and gas companies are alike, each profit protection plan is a unique mix of similar solutions. Oil and gas production companies most often try to lower operating costs by vigorously selling noncore properties or business units and reducing staff. The paper discusses measures taken by oil and gas companies to lower costs

  13. Stages of Colonialism in Africa: From Occupation of Land to Occupation of Being

    Directory of Open Access Journals (Sweden)

    Hussein A. Bulhan

    2015-08-01

    Full Text Available This paper draws primarily on my own scholarship, supplemented by the limited academic resources available in the “peripheries” of the world where I live and work (namely, Somali society and Darfur, Sudan, to consider the relationship between colonialism and psychology. I first consider the history of psychology in justifying and bolstering oppression and colonialism. I then consider the ongoing intersection of colonialism and psychology in the form of metacolonialism (or coloniality. I end with thoughts about decolonizing psychological science in teaching, social, and clinical practice. To decolonize psychological science, it is necessary to transform its focus from promotion of individual happiness to cultivation of collective well-being, from a concern with instinct to promotion of human needs, from prescriptions for adjustment to affordances for empowerment, from treatment of passive victims to creation of self-determining actors, and from globalizing, top-down approaches to context-sensitive, bottom-up approaches. Only then will the field realize its potential to advance Frantz Fanon’s call for humane and just social order.

  14. La partialité par les projets

    Directory of Open Access Journals (Sweden)

    Sarah Stroud

    2008-02-01

    Full Text Available This paper investigates how we can most effectively argue that partiality toward certain people and not others is morally permissible. Philosophers who strongly insist that morality must leave room for partiality have not made explicit their basis for this conclusion; the present paper comparatively assesses a variety of possible argument strategies which could be deployed in this regard. One promising strategy exploits the acknowledged force of the argument from “the personal point of view,” here interpreted as referring specifically to an agent’s projects. If moral demands must be tempered in light of the special significance to an agent of his own projects, then perhaps the agent’s partial attachments to other people should also receive a measure of protection from impartial moral claims. The case is bolstered by noting the ubiquity of plural or collective agency in contexts of close personal relations: often the two (or more agents in such relationships together pursue joint projects and even constitute a plural agent. This approach does justify special moral treatment of one’s co-agents, although it does not match our initial conception of partiality in all respects.

  15. Wind energy: Past experience and future

    International Nuclear Information System (INIS)

    Reductions in the cost of producing wind energy are helping to make this renewable energy source competitive with conventional energy sources. The market for this type of energy in Italy, however, hasn't yet gained a foothold even though close examination of Italy's geomorphology reveals that this country is in fact endowed with many areas having good potential for wind power production. This paper discusses the measures to be taken to bolster wind energy commercialization efforts in Italy. It provides a brief assessment of the current state of wind power technology, national and international market trends, and the directions being taken by other national governments to promote wind turbine manufacturing industries and applications. The comparative analysis indicates that in order to have this energy source alternative taken seriously as an economically viable energy option in Italy, greater financial assistance should be given to local manufacturers involved in commercialization efforts. In addition, a suitable rate structure should be created favouring wind power by taking into account cost benefits afforded by this renewable energy source in terms of reduced air pollution, as well as, reduced national dependency on foreign energy imports

  16. A Social Ecological Model of Syndemic Risk affecting Women with and At-Risk for HIV in Impoverished Urban Communities.

    Science.gov (United States)

    Batchelder, A W; Gonzalez, J S; Palma, A; Schoenbaum, E; Lounsbury, D W

    2015-12-01

    Syndemic risk is an ecological construct, defined by co-occurring interdependent socio-environmental, interpersonal and intrapersonal determinants. We posited syndemic risk to be a function of violence, substance use, perceived financial hardship, emotional distress and self-worth among women with and at-risk for HIV in an impoverished urban community. In order to better understand these interrelationships, we developed and validated a system dynamics (SD) model based upon peer-reviewed literature; secondary data analyses of a cohort dataset including women living with and at-risk of HIV in Bronx, NY (N = 620); and input from a Bronx-based community advisory board. Simulated model output revealed divergent levels and patterns of syndemic risk over time across different sample profiles. Outputs generated new insights about how to effectively explore multicomponent multi-level programs in order to strategically develop more effective services for this population. Specifically, the model indicated that effective multi-level interventions might bolster women's resilience by increasing self-worth, which may result in decreased perceived financial hardship and risk of violence. Overall, our stakeholder-informed model depicts how self-worth may be a major driver of vulnerability and a meaningful addition to syndemic theory affecting this population. PMID:26370203

  17. The study of perceived stress, coping strategy and self-efficacy of Chinese undergraduate nursing students in clinical practice.

    Science.gov (United States)

    Zhao, Fang-Fang; Lei, Xiao-Ling; He, Wei; Gu, Yan-Hong; Li, Dong-Wen

    2015-08-01

    The aim of the study was to explore the coping strategy and the effects of self-efficacy of Chinese undergraduate nursing students when they face the stress in clinical practice. Convenience sampling was used to recruit undergraduate nursing students in Mainland China who have practiced 3 months in hospitals in their final college year. Self-report questionnaires including demographics, Perceived Stress Scale, coping behaviour inventory and Generalized Self-Efficacy Scale were collected. The results showed that during clinical practice, assignments and workload were the most common stress to students; transference was the most frequently used coping strategy by students. Self-efficacy not only had a positive main effect in predicting the frequency of use of staying optimistic and problem solving strategies but also moderated the effects of stress from taking care of patients on transference strategy, as well as stress from assignments and workload on problem solving strategy. It is essential to bolster the students' self-efficacy to reduce stress and adopt positively the coping strategies during clinical practice. PMID:24750234

  18. Gravitational anomalies and one dimensional behaviour of black holes

    CERN Document Server

    Majhi, Bibhas Ranjan

    2015-01-01

    It has been pointed out by Bekenstein and Mayo that the behavior of the Black hole's entropy or information flow is similar to that through one-dimensional channel. Here I analyse the same issue with the use of gravitational anomalies. The rate of the entropy change ($\\dot{S}$) and the power ($P$) of the Hawking emission are calculated from the relevant components of the anomalous stress-tensor under the Unruh vacuum condition. I show that the dependence of $\\dot{S}$ on power is $\\dot{S}\\propto P^{1/2}$ which is identical to that for the information flow in one dimensional system. This is established by using the ($1+1$) dimensional gravitational anomalies first. Then the fact is further bolstered by considering the ($1+3$) dimensional gravitational anomalies. It is found that in the former case, the proportionality constant is exactly identical to one dimensional situation, known as Pendry's formula, while in later situation its value decreases.

  19. Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

    Science.gov (United States)

    Eruslanov, Evgeniy B.; Bhojnagarwala, Pratik S.; Quatromoni, Jon G.; Stephen, Tom Li; Ranganathan, Anjana; Deshpande, Charuhas; Akimova, Tatiana; Vachani, Anil; Litzky, Leslie; Hancock, Wayne W.; Conejo-Garcia, José R.; Feldman, Michael; Albelda, Steven M.; Singhal, Sunil

    2014-01-01

    Infiltrating inflammatory cells are highly prevalent within the tumor microenvironment and mediate many processes associated with tumor progression; however, the contribution of specific populations remains unclear. For example, the nature and function of tumor-associated neutrophils (TANs) in the cancer microenvironment is largely unknown. The goal of this study was to provide a phenotypic and functional characterization of TANs in surgically resected lung cancer patients. We found that TANs constituted 5%–25% of cells isolated from the digested human lung tumors. Compared with blood neutrophils, TANs displayed an activated phenotype (CD62LloCD54hi) with a distinct repertoire of chemokine receptors that included CCR5, CCR7, CXCR3, and CXCR4. TANs produced substantial quantities of the proinflammatory factors MCP-1, IL-8, MIP-1α, and IL-6, as well as the antiinflammatory IL-1R antagonist. Functionally, both TANs and neutrophils isolated from distant nonmalignant lung tissue were able to stimulate T cell proliferation and IFN-γ release. Cross-talk between TANs and activated T cells led to substantial upregulation of CD54, CD86, OX40L, and 4-1BBL costimulatory molecules on the neutrophil surface, which bolstered T cell proliferation in a positive-feedback loop. Together our results demonstrate that in the earliest stages of lung cancer, TANs are not immunosuppressive, but rather stimulate T cell responses. PMID:25384214

  20. A 26-year Composite Stable Isotope Record of Precipitation, Humidity and El Niño in the Spines of Saguaro Cactus, Carnegiea gigantea.

    Science.gov (United States)

    English, N. B.; Dettman, D. L.; Williams, D. G.

    2008-12-01

    Seasonal cycles of rainfall and humidity are recorded by stable isotopes in the spines of columnar cactuses. Multi-decadal δ18O and δ13C records of spine series from five saguaro cactuses, dated using bomb radiocarbon and semi-annual variations in δ13C, demonstrate the reproducibility of a climate signal. For δ18O and δ13C, the expressed population signal between 1980 and 2006 is 0.68 and 0.66, respectively, but 0.76 and 0.59 between 1980 and 1997, suggesting that age/height related effects are present in isotopic spine series. Composite δ18O and δ13C records constructed from five spine series show significant relationships to external climate forcing. Once dating errors are corrected, mean annual spine δ18O is negatively correlated with total annual precipitation (TAP) from November through October (P 2‰) in the maximum annual spine δ18O are positively correlated with the Southern Oscillation Index (P < 0.01). We hypothesize these decreases are caused by El Niño enhanced winter rainfall. While less significant, minimum annual δ13C is negatively correlated with TAP (P < 0.05) and mean nighttime VPD (P < 0.05). These results bolster proposed mechanistic models of isotopic variation in the spines of columnar cactuses and demonstrate the use of isotopic spine series as climate proxies.

  1. Bringing Back the Social Affordances of the Paper Memo to Aerospace Systems Engineering Work

    Science.gov (United States)

    Davidoff, Scott; Holloway, Alexandra

    2014-01-01

    Model-based systems engineering (MBSE) is a relatively new field that brings together the interdisciplinary study of technological components of a project (systems engineering) with a model-based ontology to express the hierarchical and behavioral relationships between the components (computational modeling). Despite the compelling promises of the benefits of MBSE, such as improved communication and productivity due to an underlying language and data model, we observed hesitation to its adoption at the NASA Jet Propulsion Laboratory. To investigate, we conducted a six-month ethnographic field investigation and needs validation with 19 systems engineers. This paper contributes our observations of a generational shift in one of JPL's core technologies. We report on a cultural misunderstanding between communities of practice that bolsters the existing technology drag. Given the high cost of failure, we springboard our observations into a design hypothesis - an intervention that blends the social affordances of the narrative-based work flow with the rich technological advantages of explicit data references and relationships of the model-based approach. We provide a design rationale, and the results of our evaluation.

  2. Two highly similar LAEDDTNAQKT and LTDKIGTEI epitopes in G glycoprotein may be useful for effective epitope based vaccine design against pathogenic Henipavirus.

    Science.gov (United States)

    Parvege, Md Masud; Rahman, Monzilur; Nibir, Yead Morshed; Hossain, Mohammad Shahnoor

    2016-04-01

    Nipah virus and Hendra virus, two members of the genus Henipavirus, are newly emerging zoonotic pathogens which cause acute respiratory illness and severe encephalitis in human. Lack of the effective antiviral therapy endorses the urgency for the development of vaccine against these deadly viruses. In this study, we employed various computational approaches to identify epitopes which has the potential for vaccine development. By analyzing the immune parameters of the conserved sequences of G glycoprotein using various databases and bioinformatics tools, we identified two potential epitopes which may be used as peptide vaccines. Using different B cell epitope prediction servers, four highly similar B cell epitopes were identified. Immunoinformatics analyses revealed that LAEDDTNAQKT is a highly flexible and accessible B-cell epitope to antibody. Highly similar putative CTL epitopes were analyzed for their binding with the HLA-C 12*03 molecule. Docking simulation assay revealed that LTDKIGTEI has significantly lower binding energy, which bolstered its potential as epitope-based vaccine design. Finally, cytotoxicity analysis has also justified their potential as promising epitope-based vaccine candidate. In sum, our computational analysis indicates that either LAEDDTNAQKT or LTDKIGTEI epitope holds a promise for the development of universal vaccine against all kinds of pathogenic Henipavirus. Further in vivo and in vitro studies are necessary to validate the obtained findings.

  3. The effects of parental mental health and social-emotional coping on adolescent eating disorder attitudes and behaviors.

    Science.gov (United States)

    Martinson, Laura E; Esposito-Smythers, Christianne; Blalock, Dan V

    2016-10-01

    This study examined whether social-emotional coping skills moderate the association between parental mental health symptoms and adolescent disordered eating attitudes and behaviors in a clinical sample of adolescents with internalizing and/or externalizing symptoms. Fifty-nine adolescent-parent dyads (N = 118 total participants) recruited from a metropolitan area in the Northeastern United States completed assessments at baseline and 12-month follow-up. Generally, higher parental depression and anxiety were only found to be associated with greater disordered eating attitudes and behaviors among adolescents who reported poorer (versus stronger) emotional awareness/expression skills and less (versus greater) ability to regulate emotions. Results may suggest that adolescents who lack the ability to effectively recognize, express, and manage negative emotions that arise in the context of a challenging home environment may be at greater risk for engaging in maladaptive coping behaviors, such as disordered eating. Thus, bolstering adolescent social-emotional coping skills may help protect against adolescent disordered eating. PMID:27567519

  4. Extending the Fermi - Swift Joint AGN Sample

    Science.gov (United States)

    Shrader, Chris R.; Macomb, D. J.

    2014-01-01

    The Swift BAT and the Fermi LAT each provide excellent sky coverage and have led to impressive compilations of extragalactic source catalogs. For the most part they sample separate AGN subpopulations - Swift the lower-luminosity and relatively nearby Seyfert galaxies while the Fermi sample is dominated by blazars and does not include any radio-quiet objects. The overlap between these samples is among the radio-loud subset of the Swift sample as has been discussed elsewhere in the literature. The observable properties at these two bands - flux and spectral indices - are not expected to be well correlated as they sample different portions of the synchrotron self-Compton (SSC) spectral energy distribution. In this contribution we consider an extension of the high-latitude Swift sample by relaxing the significance cut to less than 5 standard deviations and consider the overlap of that subsample with the Fermi AGN catalog. While such a threshold is generally inadvisable as it introduces the strong possibility of spurious detections, the objects of the overlapping sample which are detected at high significance in Fermi can be considered as reasonably high-confidence Swift detections. For example, there are 190 Swift sub-5-sigma Swift sources that have significance >2-sigma with Fermi counterparts, whereas we predict only ~5 due to statistical fluctuation. We also investigate any coincident INTEGRAL/IBIS observations to further bolster or diminish candidate Swift detections. We present our correlation analyses and offer interpretation in the context of the blazar sequence.

  5. Beyond the organ donor card: the effect of knowledge, attitudes, and values on willingness to communicate about organ donation to family members.

    Science.gov (United States)

    Morgan, Susan E; Miller, Jenny K

    2002-01-01

    Although numerous studies have examined many of the predictors of signing an organ donor card, including knowledge, attitudes, values, and demographic variables, very few have examined the factors associated with individuals' willingness to communicate about organ donation with family members. Because organ donation does not take place without the permission of a person's next-of-kin, government agencies and organ procurement organizations have targeted communication with family members as a primary objective of organ donation campaigns. This study reports the results of a survey of a stratified random sample of adults at 2 local sites of a national employer. Results indicate that knowledge, attitude, and altruism are significantly related to 2 measures of willingness to communicate: past behavior (whether respondents had already discussed organ donation with family members) and a scale measuring willingness to communicate about organ donation in the future. Because the quality of discussions between the potential donor and his or her family will depend on how well the donor is able to address vital issues regarding donation, it is concluded that campaigns seeking to promote communication between family members about organ donation must simultaneously seek to increase knowledge, debunk myths, and bolster positive attitudes about donation.

  6. Commensal enteric bacteria lipopolysaccharide impairs host defense against disseminated Candida albicans fungal infection.

    Science.gov (United States)

    Jiang, T T; Chaturvedi, V; Ertelt, J M; Xin, L; Clark, D R; Kinder, J M; Way, S S

    2015-07-01

    Commensal enteric bacteria maintain systemic immune responsiveness that protects against disseminated or localized infection in extra-intestinal tissues caused by pathogenic microbes. However, as shifts in infection susceptibility after commensal bacteria eradication have primarily been probed using viruses, the broader applicability to other pathogen types remains undefined. In sharp contrast to diminished antiviral immunity, we show commensal bacteria eradication bolsters protection against disseminated Candida albicans fungal infection. Enhanced antifungal immunity reflects more robust systemic expansion of Ly6G(hi)Ly6C(int) neutrophils, and their mobilization into infected tissues among antibiotic-treated compared with commensal bacteria-replete control mice. Reciprocally, depletion of neutrophils from expanded levels or intestinal lipopolysaccharide reconstitution overrides the antifungal protective benefits conferred by commensal bacteria eradication. This discordance in antifungal compared with antiviral immunity highlights intrinsic differences in how commensal bacteria control responsiveness for specific immune cell subsets, because pathogen-specific CD8(+) T cells that protect against viruses were suppressed similarly after C. albicans and influenza A virus infection. Thus, positive calibration of antiviral immunity by commensal bacteria is counterbalanced by restrained activation of other immune components that confer antifungal immunity.

  7. Peripheral Visual Cues: Their Fate in Processing and Effects on Attention and Temporal-Order Perception

    Science.gov (United States)

    Tünnermann, Jan; Scharlau, Ingrid

    2016-01-01

    Peripheral visual cues lead to large shifts in psychometric distributions of temporal-order judgments. In one view, such shifts are attributed to attention speeding up processing of the cued stimulus, so-called prior entry. However, sometimes these shifts are so large that it is unlikely that they are caused by attention alone. Here we tested the prevalent alternative explanation that the cue is sometimes confused with the target on a perceptual level, bolstering the shift of the psychometric function. We applied a novel model of cued temporal-order judgments, derived from Bundesen's Theory of Visual Attention. We found that cue–target confusions indeed contribute to shifting psychometric functions. However, cue-induced changes in the processing rates of the target stimuli play an important role, too. At smaller cueing intervals, the cue increased the processing speed of the target. At larger intervals, inhibition of return was predominant. Earlier studies of cued TOJs were insensitive to these effects because in psychometric distributions they are concealed by the conjoint effects of cue–target confusions and processing rate changes.

  8. Exploring the Role of Self-Esteem and Parenting Patterns on Alcohol Use and Abuse Among Adolescents.

    Science.gov (United States)

    Glozah, Franklin N

    2014-11-01

    The type of parental child-rearing practices used by parents and guardians substantially influence children's self-esteem and consequently their decision to engage in alcohol use, its abuse. The aim of this study was to explore the role of self-esteem and parenting patterns on alcohol use and abuse among adolescents. Three hundred and sixteen boys and girls in Senior High Schools completed self-report questionnaires assessing self-esteem, parenting patterns and alcohol use and abuse. The results showed that while girls reported lesser self-esteem than boys, boys reported higher levels of alcohol use and abuse than girls. Also, authoritative parenting pattern had a positive effect on self-esteem and a negative effect on alcohol use. On the other hand, authoritarian and permissive parenting patterns had negative effects on self-esteem and positive effects on alcohol use, with slight variations. These results provide valuable information regarding strategies aimed at fostering parent-child relationship and rapport with the ultimate aim of bolstering the self-esteem of adolescents to subsequently eschew insalubrious behaviour, particularly alcohol use and abuse. PMID:26973951

  9. From road to lab to math: the co-evolution of technological, regulatory, and organizational innovations for automotive crash testing.

    Science.gov (United States)

    Leonardi, Paul M

    2010-04-01

    Today, in the midst of economic crisis, senior executives at US automakers and influential industry analysts frequently reflect on the progression that safety testing has taken from the crude trials done on the road, to controlled laboratory experiments, and to today's complex math-based simulation models. They use stories of this seemingly linear and natural sequence to justify further investment in simulation technologies. The analysis presented in this paper shows that change in the structures of automakers' organizations co-evolved with regulations specifying who was at fault in vehicle impacts, how vehicles should be built to withstand the force of an impact, and how testing should be done to assure that vehicles met those requirements. Changes in the regulatory environment were bolstered by new theories about crash test dynamics and changing technologies with which to test those theories. Thus, as new technological and regulatory innovations co-evolved with innovations in organizational structuring, ideas about how to best conduct crash tests shifted and catalyzed new cycles of technological, regulatory, and organizational innovation. However, this co-evolutionary story tells us that the move from road to lab to math was not natural or linear as today's managerial rhetoric would have us believe. Rather, the logic of math-based simulation was the result of technological, regulatory and organizational changes that created an industry-wide ideology that supported the move toward math while making it appear natural within the shifting structure of the industry. PMID:20527322

  10. Exploiting dimensionality and defect mitigation to create tunable microwave dielectrics

    Science.gov (United States)

    Lee, Che-Hui; Orloff, Nathan D.; Birol, Turan; Zhu, Ye; Goian, Veronica; Rocas, Eduard; Haislmaier, Ryan; Vlahos, Eftihia; Mundy, Julia A.; Kourkoutis, Lena F.; Nie, Yuefeng; Biegalski, Michael D.; Zhang, Jingshu; Bernhagen, Margitta; Benedek, Nicole A.; Kim, Yongsam; Brock, Joel D.; Uecker, Reinhard; Xi, X. X.; Gopalan, Venkatraman; Nuzhnyy, Dmitry; Kamba, Stanislav; Muller, David A.; Takeuchi, Ichiro; Booth, James C.; Fennie, Craig J.; Schlom, Darrell G.

    2013-10-01

    The miniaturization and integration of frequency-agile microwave circuits--relevant to electronically tunable filters, antennas, resonators and phase shifters--with microelectronics offers tantalizing device possibilities, yet requires thin films whose dielectric constant at gigahertz frequencies can be tuned by applying a quasi-static electric field. Appropriate systems such as BaxSr1-xTiO3 have a paraelectric-ferroelectric transition just below ambient temperature, providing high tunability. Unfortunately, such films suffer significant losses arising from defects. Recognizing that progress is stymied by dielectric loss, we start with a system with exceptionally low loss--Srn+1TinO3n+1 phases--in which (SrO)2 crystallographic shear planes provide an alternative to the formation of point defects for accommodating non-stoichiometry. Here we report the experimental realization of a highly tunable ground state arising from the emergence of a local ferroelectric instability in biaxially strained Srn+1TinO3n+1 phases with n>=3 at frequencies up to 125GHz. In contrast to traditional methods of modifying ferroelectrics--doping or strain--in this unique system an increase in the separation between the (SrO)2 planes, which can be achieved by changing n, bolsters the local ferroelectric instability. This new control parameter, n, can be exploited to achieve a figure of merit at room temperature that rivals all known tunable microwave dielectrics.

  11. Of Stars and Harlow Shapley

    Science.gov (United States)

    Palmeri, J.

    2016-01-01

    For much of the twentieth century, the astronomer and longtime director of the Harvard College Observatory, Harlow Shapley (1885-1972), embodied the public face of astronomy. From the 1920s through the 1960s he introduced millions to the wonders of the night sky. His compelling vision of humanity's place in the universe and moving message about cosmic connections inspired many who had never looked through a telescope, visited a planetarium, or taken an astronomy class. He encouraged readers and audiences to learn more about astronomy and other sciences. Over the course of a long career, Shapley not only bolstered the image of astronomy, but also the role of the astronomer as a public intellectual and spokesperson for science. Shapley's early years on the newspaper beat honed his storytelling, and he then put these skills to use as a promoter and fundraiser for astronomy and science at Harvard. He used a variety of means to convey his message beyond the observatory, including radio talks, lectures, magazine articles, television appearances, and popular books. He also narrated an award-winning animated film based on one of his most widely read books, Of Stars and Men. Through words, voice, and visuals, Shapley offered the world an eloquent perspective on the cosmos and a timely message about the significance of science for society. In this paper I focus on how Shapley conveyed the meaning and value of astronomical inquiry, and I explore audience reception of the messages and images he used to popularize astronomy.

  12. A New Spin on Photoemission Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Jozwiak, Chris [Univ. of California, Berkeley, CA (United States)

    2008-12-01

    The electronic spin degree of freedom is of general fundamental importance to all matter. Understanding its complex roles and behavior in the solid state, particularly in highly correlated and magnetic materials, has grown increasingly desirable as technology demands advanced devices and materials based on ever stricter comprehension and control of the electron spin. However, direct and efficient spin dependent probes of electronic structure are currently lacking. Angle Resolved Photoemission Spectroscopy (ARPES) has become one of the most successful experimental tools for elucidating solid state electronic structures, bolstered by-continual breakthroughs in efficient instrumentation. In contrast, spin-resolved photoemission spectroscopy has lagged behind due to a lack of similar instrumental advances. The power of photoemission spectroscopy and the pertinence of electronic spin in the current research climate combine to make breakthroughs in Spin and Angle Resolved Photoemission Spectroscopy (SARPES) a high priority . This thesis details the development of a unique instrument for efficient SARPES and represents a radical departure from conventional methods. A custom designed spin polarimeter based on low energy exchange scattering is developed, with projected efficiency gains of two orders of magnitude over current state-of-the-art polarimeters. For energy analysis, the popular hemispherical analyzer is eschewed for a custom Time-of-Flight (TOF) analyzer offering an additional order of magnitude gain in efficiency. The combined instrument signifies the breakthrough needed to perform the high resolution SARPES experiments necessary for untangling the complex spin-dependent electronic structures central to today's condensed matter physics.

  13. A New Spin on Photoemission Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Advanced Light Source; Jozwiak, Chris

    2008-12-18

    The electronic spin degree of freedom is of general fundamental importance to all matter. Understanding its complex roles and behavior in the solid state, particularly in highly correlated and magnetic materials, has grown increasingly desirable as technology demands advanced devices and materials based on ever stricter comprehension and control of the electron spin. However, direct and efficient spin dependent probes of electronic structure are currently lacking. Angle Resolved Photoemission Spectroscopy (ARPES) has become one of the most successful experimental tools for elucidating solid state electronic structures, bolstered bycontinual breakthroughs in efficient instrumentation. In contrast, spin-resolved photoemission spectroscopy has lagged behind due to a lack of similar instrumental advances. The power of photoemission spectroscopy and the pertinence of electronic spin in the current research climate combine to make breakthroughs in Spin and Angle Resolved Photoemission Spectroscopy (SARPES) a high priority . This thesis details the development of a unique instrument for efficient SARPES and represents a radical departure from conventional methods. A custom designed spin polarimeter based on low energy exchange scattering is developed, with projected efficiency gains of two orders of magnitude over current state-of-the-art polarimeters. For energy analysis, the popular hemispherical analyzer is eschewed for a custom Time-of-Flight (TOF) analyzer offering an additional order of magnitude gain in efficiency. The combined instrument signifies the breakthrough needed to perform the high resolution SARPES experiments necessary for untangling the complex spin-dependent electronic structures central to today?s condensed matter physics.

  14. [The Health Academy Program as a strategy to promote health and healthy lifestyles: the national implementation scenario].

    Science.gov (United States)

    Sá, Gisele Balbino Araujo Rodrigues de; Dornelles, Gabriela Chagas; Cruz, Kátia Godoy; Amorim, Roberta Corrêa de Araújo; Andrade, Silvânia Suely Caribé de Araújo; Oliveira, Taís Porto; Silva, Marta Maria Alves da; Malta, Deborah Carvalho; Souza, Maria de Fátima Marinho de

    2016-06-01

    The National Health Promotion Policy reasserted the Brazilian Ministry of Health's commitment to bolster the promotion of health in the Unified Health System. In this context, the Health Academy Program constitutes a new tool of the health network for the enhancement of individual and collective primary healthcare. The scope of this study is to present the program implementation scenario, describing characteristics of its operation in the country. Data were collected through an electronic form sent to all Municipal Health Departments that received federal resources to implement the program. The response rate was 85%, corresponding to 2,418 municipalities. A total of 856 centers were found to be in operation, primarily promoting physical exercise, healthy eating and health education. The main participants were adults and the elderly. Difficulties reported by the administrators involve the inclusion of children and adolescents and the hiring of professionals. Over 90% of the program centers do not depend exclusively on federal funding for operation and receive municipal support to conduct their activities. The results show the potential of the program as a strategy to promote healthcare in the community nationwide in Brazil. PMID:27276540

  15. Stabilization of memory States by stochastic facilitating synapses.

    Science.gov (United States)

    Miller, Paul

    2013-12-06

    Bistability within a small neural circuit can arise through an appropriate strength of excitatory recurrent feedback. The stability of a state of neural activity, measured by the mean dwelling time before a noise-induced transition to another state, depends on the neural firing-rate curves, the net strength of excitatory feedback, the statistics of spike times, and increases exponentially with the number of equivalent neurons in the circuit. Here, we show that such stability is greatly enhanced by synaptic facilitation and reduced by synaptic depression. We take into account the alteration in times of synaptic vesicle release, by calculating distributions of inter-release intervals of a synapse, which differ from the distribution of its incoming interspike intervals when the synapse is dynamic. In particular, release intervals produced by a Poisson spike train have a coefficient of variation greater than one when synapses are probabilistic and facilitating, whereas the coefficient of variation is less than one when synapses are depressing. However, in spite of the increased variability in postsynaptic input produced by facilitating synapses, their dominant effect is reduced synaptic efficacy at low input rates compared to high rates, which increases the curvature of neural input-output functions, leading to wider regions of bistability in parameter space and enhanced lifetimes of memory states. Our results are based on analytic methods with approximate formulae and bolstered by simulations of both Poisson processes and of circuits of noisy spiking model neurons.

  16. Precision measures of the primordial abundance of deuterium

    CERN Document Server

    Cooke, Ryan; Jorgenson, Regina A; Murphy, Michael T; Steidel, Charles C

    2013-01-01

    We report the discovery of deuterium absorption in the very metal-poor ([Fe/H] = -2.87) damped Lyman-alpha system at z_abs = 3.06726 towards the QSO SDSS J1358+6522. On the basis of 13 resolved D I absorption lines and the damping wings of the H I Lyman alpha transition, we have obtained a new, precise measure of the primordial abundance of deuterium. Furthermore, to bolster the present statistics of precision D/H measures, we have reanalyzed all of the known deuterium absorption-line systems that satisfy a set of strict criteria. We have adopted a blind analysis strategy (to remove human bias), and developed a software package that is specifically designed for precision D/H abundance measurements. For this reanalyzed sample of systems, we obtain a weighted mean of (D/H)_p = (2.53 +/- 0.04) x 10^-5, corresponding to a Universal baryon density 100 Omega_b h^2 = 2.202 +/- 0.045 for the standard model of Big Bang Nucleosynthesis. By combining our measure of (D/H)_p with observations of the cosmic microwave backg...

  17. Generalized trust and intelligence in the United States.

    Science.gov (United States)

    Carl, Noah; Billari, Francesco C

    2014-01-01

    Generalized trust refers to trust in other members of society; it may be distinguished from particularized trust, which corresponds to trust in the family and close friends. An extensive empirical literature has established that generalized trust is an important aspect of civic culture. It has been linked to a variety of positive outcomes at the individual level, such as entrepreneurship, volunteering, self-rated health, and happiness. However, two recent studies have found that it is highly correlated with intelligence, which raises the possibility that the other relationships in which it has been implicated may be spurious. Here we replicate the association between intelligence and generalized trust in a large, nationally representative sample of U.S. adults. We also show that, after adjusting for intelligence, generalized trust continues to be strongly associated with both self-rated health and happiness. In the context of substantial variation across countries, these results bolster the view that generalized trust is a valuable social resource, not only for the individual but for the wider society as well. PMID:24619035

  18. Proximity of snacks to beverages increases food consumption in the workplace: A field study.

    Science.gov (United States)

    Baskin, Ernest; Gorlin, Margarita; Chance, Zoë; Novemsky, Nathan; Dhar, Ravi; Huskey, Kim; Hatzis, Michelle

    2016-08-01

    In an effort to bolster employee satisfaction, many employers provide free snacks at the office. Unfortunately, keeping employees happy can conflict with the goal of keeping them healthy, since increased snacking at work can contribute to overeating and obesity. Building on the growing body of research in choice architecture, we tested one factor that might influence snack consumption without impacting satisfaction: the relative distance between snacks and beverages. In a large field study at Google, we measured snack consumption when snacks were closer to or farther from beverages. We found that employees who used the beverage station closer to the snack station were more likely to take a snack- the likelihood of snacking increased from 12% to 23% for men and from 13% to 17% for women when the beverage station closest to the snack station was used. These results imply that employers and even families could reduce snack consumption easily, cheaply, and without backlash, by increasing the relative distance between beverages and snacks. PMID:27112315

  19. Regulatory T Cells in Colorectal Cancer: From Biology to Prognostic Relevance

    Energy Technology Data Exchange (ETDEWEB)

    Mougiakakos, Dimitrios [Department of Oncology and Pathology, Immune and Gene Therapy Unit, Cancer Centre Karolinska, CCK R8:01, 17176 Stockholm (Sweden)

    2011-03-29

    Regulatory T cells (Tregs) were initially described as “suppressive” lymphocytes in the 1980s. However, it took almost 20 years until the concept of Treg-mediated immune control in its present form was finally established. Tregs are obligatory for self-tolerance and defects within their population lead to severe autoimmune disorders. On the other hand Tregs may promote tolerance for tumor antigens and even hamper efforts to overcome it. Intratumoral and systemic accumulation of Tregs has been observed in various types of cancer and is often linked to worse disease course and outcome. Increase of circulating Tregs, as well as their presence in mesenteric lymph nodes and tumor tissue of patients with colorectal cancer de facto suggests a strong involvement of Tregs in the antitumor control. This review will focus on the Treg biology in view of colorectal cancer, means of Treg accumulation and the controversies regarding their prognostic significance. In addition, a concise overview will be given on how Tregs and their function can be targeted in cancer patients in order to bolster an inherent immune response and/or increase the efficacy of immunotherapeutic approaches.

  20. On the evolutionary advantage of multi-cusped teeth.

    Science.gov (United States)

    Constantino, Paul J; Bush, Mark B; Barani, Amir; Lawn, Brian R

    2016-08-01

    A hallmark of mammalian evolution is a progressive complexity in postcanine tooth morphology. However, the driving force for this complexity remains unclear: whether to expand the versatility in diet source, or to bolster tooth structural integrity. In this study, we take a quantitative approach to this question by examining the roles of number, position and height of multiple cusps in determining sustainable bite forces. Our approach is to use an extended finite-element methodology with due provision for step-by-step growth of an embedded crack to determine how fracture progresses with increasing occlusal load. We argue that multi-cusp postcanine teeth are well configured to withstand high bite forces provided that multiple cusps are contacted simultaneously to share the load. However, contact on a single near-wall cusp diminishes the strength. Location of the load points and cusp height, rather than cusp number or radius, are principal governing factors. Given these findings, we conclude that while complex tooth structures can enhance durability, increases in cusp number are more likely to be driven by the demands of food manipulation. Structural integrity of complex teeth is maintained when individual cusps remain sufficiently distant from the side walls and do not become excessively tall relative to tooth width. PMID:27558851

  1. Environmental valuation for long-term strategic planning. The case of the Brazilian power sector

    International Nuclear Information System (INIS)

    If not properly dealt with over compatible horizons, environmental issues may cause ventures to incur higher costs and extend over longer implementation periods. Prompted by the uncertainties and risks inherent in these issues, as well as by the need for long-term plans to incorporate sustainable development principles, the Brazilian Power Sector is encouraging the inclusion of environmental aspects as a decision variable right from the start of the planning cycle. The purpose of this paper is to bolster efforts to include in this sector's expansion plans, costs resulting from environmental degradation of the environment. The paper offers an overview of the methodology developed to assess and include in long-term planning for this sector, external environmental costs linked to hydro-power and thermo-power generation. It suggests the use of environmental economic valuation techniques a practice commonly used to analyze the degradation of natural capital in various countries as well as assessing projects and programs, adopting the premises and simplifications required for application over the longer term.21 refs

  2. The Alliance Negotiation Scale: A psychometric investigation.

    Science.gov (United States)

    Doran, Jennifer M; Safran, Jeremy D; Muran, J Christopher

    2016-08-01

    This study investigates the utility and psychometric properties of a new measure of psychotherapy process, the Alliance Negotiation Scale (ANS; Doran, Safran, Waizmann, Bolger, & Muran, 2012). The ANS was designed to operationalize the theoretical construct of negotiation (Safran & Muran, 2000), and to extend our current understanding of the working alliance concept (Bordin, 1979). The ANS was also intended to improve upon existing measures such as the Working Alliance Inventory (WAI; Horvath & Greenberg, 1986, 1989) and its short form (WAI-S; Tracey & Kokotovic, 1989) by expanding the emphasis on negative therapy process. The present study investigates the psychometric validity of the ANS test scores and interpretation-including confirming its original factor structure and evaluating its internal consistency and construct validity. Construct validity was examined through the ANS' convergence and divergence with several existing scales that measure theoretically related constructs. The results bolster and extend previous findings about the psychometric integrity of the ANS, and begin to illuminate the relationship between negotiation and other important variables in psychotherapy research. (PsycINFO Database Record PMID:26460895

  3. Improving the efficacy of appearance-based sun exposure interventions with the terror management health model.

    Science.gov (United States)

    Morris, Kasey Lynn; Cooper, Douglas P; Goldenberg, Jamie L; Arndt, Jamie; Gibbons, Frederick X

    2014-01-01

    The terror management health model (TMHM) suggests that when thoughts of death are accessible people become increasingly motivated to bolster their self-esteem relative to their health, because doing so offers psychological protection against mortality concerns. Two studies examined sun protection intentions as a function of mortality reminders and an appearance-based intervention. In Study 1, participants given a sun protection message that primed mortality and shown a UV-filtered photo of their face reported greater intentions to use sun protection on their face, and took more sunscreen samples than participants shown a regular photo of their face. In Study 2, reminders of mortality increased participants' intentions to use facial sun protection when the UV photo was specifically framed as revealing appearance consequences of tanning, compared to when the photo was framed as revealing health consequences or when no photo was shown. These findings extend the TMHM, and provide preliminary evidence that appearance-based tanning interventions have a greater influence on sun protection intentions under conditions that prime thoughts of death. We discuss implications of the findings, and highlight the need for additional research examining the applicability to long-term tanning behaviour. PMID:24811049

  4. Community rating in the absence of risk equalisation: lessons from the Irish private health insurance market.

    Science.gov (United States)

    Turner, Brian; Shinnick, Edward

    2013-04-01

    Ireland's private health insurance market operates on the basis of community rating, alongside open enrolment and lifetime cover. A risk equalisation scheme was introduced in 2003 to bolster community rating. However, in July 2008 the Irish Supreme Court set aside this scheme, on the basis of the interpretation of community rating in Irish legislation. This decision has significant implications for the Irish private health insurance market. This paper reviews the development of the market, focusing in particular on community rating. The breakdown of community rating in a market with multiple insurers with differing risk profiles is discussed. Applying this to the Irish market, it can be seen that the Irish Supreme Court judgment has significant implications for the application of community rating. Specifically, while community rating operates within plans, it no longer operates across the market, leading to high-risk lives paying more, on average, than low-risk lives. It has also led to greater opportunities for insurers to engage in market segmentation. This may have relevance for the design and operation of other community rated markets. PMID:22717020

  5. [The voice of municipal administrators on access to health in management practices].

    Science.gov (United States)

    Silva, Bela Feiman Sapiertein; Benito, Gladys Amelia Vélez

    2013-08-01

    Universal access to health services is a challenge for municipal administration in a society that treats health as a commodity and gives preference to the individual consumer to the detriment of the citizen. This study sought to identify the social representations in the narrative of local health managers in a micro-region of southeast Brazil about access to health services. It consists of qualitative research with interviews conducted with 16 managers. The Collective Subject Discourse technique was employed with the use of Qualiquantisoft software in the data analysis. Four core ideas were identified: coordination between federal states; reorganization of admission procedures; user service and the precariousness of guaranteed access. It was revealed that the quality, resolvability, approach to the user's needs and the care network organization are poorly addressed, which reflects an understanding that does not consider 'access quality and resolution.' It is understood that the managers' impotence to make changes and the lack of society and worker engagement in management bolster the supremacy of market interests and contribute to 'limited access' and the continuity of the hegemonic model of care. PMID:23896901

  6. The Technological Expansion of Sociability: Virtual Communities as Imagined Communities

    Directory of Open Access Journals (Sweden)

    Camelia Grădinaru

    2016-07-01

    Full Text Available The reception of Benedict Anderson’s ideas was very fruitful in many disciplines, and his work provided key concepts that can now throw a clarifying light in some blurry matters. The expression “imagined community” has known a remarkable proliferation, a situation that led to both the formation of a research direction and to the perpetuation of a cliché. In this respect, my article pointed out some suggestive characteristics of virtual communities, explaining why the imagined community is a valuable subject for the theorists of new media. The impossibility to know in person all the members of a big community is just one factor that determines its imagined face. Moreover, the set of values and inner presuppositions that guide the members are important bricks in the construction of community. In my opinion, the virtual community is imagined as a multi-layered experience (technological, conversational, relational etc.. The dynamic of a virtual community contains the tension amongst these layers and the degree of its imagined side depends on multiple factors. In order to illustrate these aspects, I gave a brief example by analysing a Romanian virtual community, using the triad common language – temporality – high centers. In spite of its limitations, the perspectives offered by this concept are still useful for understanding the nature of online communities. Thus, the imagined community is a valuable set of beliefs and practices that underlie and bolster the effective meaning and functioning of the virtual communities.

  7. Private Equity Capital in a Less Developed Economy: Evidence, Issues and Perspectives

    Directory of Open Access Journals (Sweden)

    Melusi Mpofu

    2015-10-01

    Full Text Available This study investigates the structure of the private equity industry and issues that impact on its development and growth in Zimbabwe. Studies conducted internationally have unequivocally demonstrated the importance of private equity investments in assisting firms at start/growth phase and decline phase. However there is a dearth of literature on how these financial intermediaries assist in unlocking firm value from an emerging markets perspective. The study uses the document analysis and an exploratory research paradigms to achieve the stated objectives. The study finds that the venture capital industry in Zimbabwe mimics similar industries in other countries except that it is constrained by market liquidity. Lack of regulation and viable business sectors coupled with excessive risks in the political economy narrows the scope of private equity operations. Several issues impacting on the development of the private equity industry are identified and evaluated. The study has policy implications for the development of regulatory framework to bolster the growth of the private equity industry in emerging market economies. This study provides new evidence and policy suggestions on the operations of the private equity industry in a liquidity constrained and less developed economy.

  8. Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

    Directory of Open Access Journals (Sweden)

    Marc Mansour

    2011-08-01

    Full Text Available Chemotherapy has been a mainstay in cancer treatment for many years. Despite some success, the cure rate with chemotherapy remains unsatisfactory in some types of cancers, and severe side effects from these treatments are a concern. Recently, understanding of the dynamic interplay between the tumor and immune system has led to the development of novel immunotherapies, including cancer vaccines. Cancer vaccines have many advantageous features, but their use has been hampered by poor immunogenicity. Many developments have increased their potency in pre-clinical models, but cancer vaccines continue to have a poor clinical track record. In part, this could be due to an inability to effectively overcome tumor-induced immune suppression. It had been generally assumed that immune-stimulatory cancer vaccines could not be used in combination with immunosuppressive chemotherapies, but recent evidence has challenged this dogma. Chemotherapies could be used to condition the immune system and tumor to create an environment where cancer vaccines have a better chance of success. Other types of immunotherapies could also be used to modulate the immune system. This review will discuss how immune modulation by chemotherapy or immunotherapy could be used to bolster the effects of cancer vaccines and discuss the advantages and disadvantages of these treatments.

  9. Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

    Energy Technology Data Exchange (ETDEWEB)

    Weir, Genevieve M. [Suite 411, 1344 Summer St., Immunovaccine Inc., Halifax, NS, B3H 0A8 (Canada); Room 11-L1, Sir Charles Tupper Building, Department of Microbiology & Immunology, Dalhousie University, 5850 College St, Halifax, NS, B3H 1X5 (Canada); Liwski, Robert S. [Room 11-L1, Sir Charles Tupper Building, Department of Microbiology & Immunology, Dalhousie University, 5850 College St, Halifax, NS, B3H 1X5 (Canada); Room 206E, Dr. D. J. Mackenzie Building, Department of Pathology, Dalhousie University, 5788 University Avenue, Halifax, NS, B3H 2Y9 (Canada); Mansour, Marc [Suite 411, 1344 Summer St., Immunovaccine Inc., Halifax, NS, B3H 0A8 (Canada)

    2011-08-05

    Chemotherapy has been a mainstay in cancer treatment for many years. Despite some success, the cure rate with chemotherapy remains unsatisfactory in some types of cancers, and severe side effects from these treatments are a concern. Recently, understanding of the dynamic interplay between the tumor and immune system has led to the development of novel immunotherapies, including cancer vaccines. Cancer vaccines have many advantageous features, but their use has been hampered by poor immunogenicity. Many developments have increased their potency in pre-clinical models, but cancer vaccines continue to have a poor clinical track record. In part, this could be due to an inability to effectively overcome tumor-induced immune suppression. It had been generally assumed that immune-stimulatory cancer vaccines could not be used in combination with immunosuppressive chemotherapies, but recent evidence has challenged this dogma. Chemotherapies could be used to condition the immune system and tumor to create an environment where cancer vaccines have a better chance of success. Other types of immunotherapies could also be used to modulate the immune system. This review will discuss how immune modulation by chemotherapy or immunotherapy could be used to bolster the effects of cancer vaccines and discuss the advantages and disadvantages of these treatments.

  10. ASTEROSEISMOLOGY OF THE SOLAR ANALOGS 16 Cyg A AND B FROM KEPLER OBSERVATIONS

    International Nuclear Information System (INIS)

    The evolved solar-type stars 16 Cyg A and B have long been studied as solar analogs, yielding a glimpse into the future of our own Sun. The orbital period of the binary system is too long to provide meaningful dynamical constraints on the stellar properties, but asteroseismology can help because the stars are among the brightest in the Kepler field. We present an analysis of three months of nearly uninterrupted photometry of 16 Cyg A and B from the Kepler space telescope. We extract a total of 46 and 41 oscillation frequencies for the two components, respectively, including a clear detection of octupole (l = 3) modes in both stars. We derive the properties of each star independently using the Asteroseismic Modeling Portal, fitting the individual oscillation frequencies and other observational constraints simultaneously. We evaluate the systematic uncertainties from an ensemble of results generated by a variety of stellar evolution codes and fitting methods. The optimal models derived by fitting each component individually yield a common age (t = 6.8 ± 0.4 Gyr) and initial composition (Zi = 0.024 ± 0.002, Yi = 0.25 ± 0.01) within the uncertainties, as expected for the components of a binary system, bolstering our confidence in the reliability of asteroseismic techniques. The longer data sets that will ultimately become available will allow future studies of differential rotation, convection zone depths, and long-term changes due to stellar activity cycles.

  11. Undocumented migration and the residential segregation of Mexicans in new destinations.

    Science.gov (United States)

    Hall, Matthew; Stringfield, Jonathan

    2014-09-01

    This study uses data from the 2000 Census and 2005-2009 American Community Survey to examine the impact of undocumented Mexican migration to new destinations on residential segregation between Mexican immigrants and native-born whites and native-born blacks. We find that Mexican-white and Mexican-black segregation is higher in new Mexican gateways than in established areas and that, for Mexican-immigrant segregation from whites, this heightened level of residential segregation in new destinations can be explained by the high presence of unauthorized Mexican immigrants living there which tends to bolster segregation between the two groups. By contrast, Mexican-immigrant segregation from native-born blacks tends to be lower in areas with larger undocumented populations, a pattern that is especially true in new destinations. Neither of these opposing effects of legal status on Mexican-immigrant segregation can be explained by compositional differences in assimilation (English ability and earnings) between documented and undocumented immigrants nor by structural variation in metropolitan areas, suggesting a unique association between legal status and segregation. PMID:24913945

  12. Wind and wildlife in the Northern Great Plains: identifying low-impact areas for wind development.

    Directory of Open Access Journals (Sweden)

    Joseph Fargione

    Full Text Available Wind energy offers the potential to reduce carbon emissions while increasing energy independence and bolstering economic development. However, wind energy has a larger land footprint per Gigawatt (GW than most other forms of energy production and has known and predicted adverse effects on wildlife. The Northern Great Plains (NGP is home both to some of the world's best wind resources and to remaining temperate grasslands, the most converted and least protected ecological system on the planet. Thus, appropriate siting and mitigation of wind development is particularly important in this region. Steering energy development to disturbed lands with low wildlife value rather than placing new developments within large and intact habitats would reduce impacts to wildlife. Goals for wind energy development in the NGP are roughly 30 GW of nameplate capacity by 2030. Our analyses demonstrate that there are large areas where wind development would likely have few additional impacts on wildlife. We estimate there are ∼1,056 GW of potential wind energy available across the NGP on areas likely to have low-impact for biodiversity, over 35 times development goals. New policies and approaches will be required to guide wind energy development to low-impact areas.

  13. TOPICAL REVIEW: Stem cells engineering for cell-based therapy

    Science.gov (United States)

    Taupin, Philippe

    2007-09-01

    Stem cells carry the promise to cure a broad range of diseases and injuries, from diabetes, heart and muscular diseases, to neurological diseases, disorders and injuries. Significant progresses have been made in stem cell research over the past decade; the derivation of embryonic stem cells (ESCs) from human tissues, the development of cloning technology by somatic cell nuclear transfer (SCNT) and the confirmation that neurogenesis occurs in the adult mammalian brain and that neural stem cells (NSCs) reside in the adult central nervous system (CNS), including that of humans. Despite these advances, there may be decades before stem cell research will translate into therapy. Stem cell research is also subject to ethical and political debates, controversies and legislation, which slow its progress. Cell engineering has proven successful in bringing genetic research to therapy. In this review, I will review, in two examples, how investigators are applying cell engineering to stem cell biology to circumvent stem cells' ethical and political constraints and bolster stem cell research and therapy.

  14. Fluid mechanics films in the 21st century

    Science.gov (United States)

    Settles, Gary; Tremblay, Gabrielle; Cimbala, John; Dodson, Lori; Miller, J. D.

    2006-11-01

    The 1960's-era National Committee for Fluid Mechanics Films produced 39 famous 16mm films - dated but still in use - with 3 million dollars of NSF funding. Here we examine the nature of new fluid mechanics films, goals, media changes, and practicality. Examples are given of new narrated videos produced to illustrate chapters of a basic fluids text and provide a ``glimpse through the laboratory window.'' Both experiments and CFD are featured, though the facilities needed for the former are declining. The fundamentally-visual nature of the topic is emphasized with no repetition of text or equations. We believe this visual nature of fluid mechanics is the key to its role in renewed efforts to bolster US science education. This is one - not the only - paradigm for new fluid mechanics films. While inflation makes such film production perhaps 6 times more expensive than in the 1960's, there are offsetting economies based on consumer video technology and digital desktop production. Nonetheless, funding new educational fluid mechanics videos in the 21st century remains a daunting prospect.

  15. Medical Subspecialty Textbooks in the 21st Century. Essential or Headed for Extinction?

    Science.gov (United States)

    Broaddus, V Courtney; Grippi, Michael A

    2015-08-01

    In recent years, the role of medical subspecialty textbooks as sources of information for students, trainees, and practicing clinicians has been challenged. Although the structure of textbooks continues to evolve from standard, printed versions to digital formats, including e-books and online texts, we maintain that the authoritative compilation of clinical and scientific material by experts in the field (i.e., a modern-day textbook) remains central to the education, training, and practice of subspecialists. Regardless of format, an effective medical subspecialty textbook is authoritative, comprehensive, and integrated in its coverage of the subject. Textbook content represents a unique synthesis of clinical and scientific material of real educational and clinical value. Incorporation of illustrations, including figures, tables, videos, and audios, bolsters the presentation and further solidifies the reader's understanding of the subject. The textbook, both printed and digital, reinforces the many widely available online resources and serves as a platform from which to evaluate other sources of information and to launch additional scientific and clinical inquiry. PMID:26177458

  16. Determining the Appropriate Package and Transportation Methodology for the Detroit Edison, Fermi II Msrs and Associated Components

    International Nuclear Information System (INIS)

    During the spring of 2005, Detroit Edison, Enrico Fermi II Nuclear Power Station (Fermi) decided to disposition two MSRs and associated components scheduled for replacement in the spring of 2006 during the MSR Replacement Outage. Of concern to Fermi was the proper packaging and transportation methodology when dis-positioning a component measuring approximately 110' in length and 13' in diameter and weighing over 300 tons. Upon removal from the Turbine Deck the retired MSRs and associated components were turned over to the Rad Waste Group for packaging and final disposition. Fermi requested quotations from vendors to package, transport, and disposition the MSRs and associated components. However, multiple Vendors informed Fermi that the size and weight of the MSRs were questionable in passing permitting requirements and would require segmentation and volume reduction on site or at a waste processor. Fermi contracted with MHF Logistical Solutions (MHF-LS) based on their ability to receive clearances for shipping the MSRs in one piece via two heavy haul rail conveyances acting as a bolstered load with professionally engineered blocking and bracing configured to support the retired MSRs. (authors)

  17. Placentation in mammals once grouped as insectivores.

    Science.gov (United States)

    Carter, Anthony M; Enders, Allen C

    2010-01-01

    Interest in insectivoran grade mammals has been reawakened by taxonomic changes that place tenrecs and golden moles in a new order and separate hedgehogs from moles, shrews and solenodons. This survey of their placentation shows there is great variation even within families. As an example three subfamilies of tenrec have been examined. The interhemal region is cellular hemomonochorial in Echinops and Microgale but endotheliochorial in Micropotamogale. Golden moles, which are placed in the same order, have hemodichorial placentation. Many insectivores have complex arrangements for histotrophic nutrition involving columnar trophoblast cells. These range from areolae in moles through complexly folded hemophagous regions in tenrecs to the trophoblastic annulus in shrews. Of these placental characters, few offer support to current phylogenies. However, the case for placing hedgehogs and gymnures in a separate order (Erinaceomorpha) is bolstered by the presence of interstitial implantation, amniogenesis by cavitation, a hemochorial barrier and a prominent spongy zone; these features do not occur in shrews, moles or solenodons (Soricomorpha). Three insectivoran grade mammals deserve close attention as they have been selected for genome sequencing. One of these, the European hedgehog (Erinaceus europaeus), has not been studied with current methodology and renewed investigation of this or the closely related genus Atelerix should be a priority.

  18. Polyacrylamide Gel-Entrapped Fungal Manganese Peroxidase from Ganoderma lucidum IBL-05 with Enhanced Catalytic, Stability, and Reusability Characteristics.

    Science.gov (United States)

    Bilal, Muhammad; Asgher, Muhammad; Iqbal, Hafiz M N

    2016-01-01

    In the present study, polyacrylamide gel (PAG) was utilized as bolster material for the immobilization of in-house extracted and partially purified manganese peroxidase (MnP) through an entrapment technique yielding significant MnP immobilization (87.3±3.3 %) and remarkable stability of the enzyme (37.2±2.4 %) after a storage period of two months at 4°C. The immobilization also increased the optimal temperature by 10 °C and provided an alkaline shift of the pH optimum. Moreover, a significant enhancement in the thermo-stability was observed. After an incubation period of 72 h at 50°C, the PAG-entrapped-MnP still exhibited 41.2 % of the initial activity, whereas the free enzyme was completely inactive. Furthermore, PAG-entrapped-MnP showed an excellent recycling efficiency and retained more than 50% of its initial activity after five consecutive reaction cycles. In conclusion, owing to the economic feasibility, carrier-supported MnP may be a promising candidate for various applications in different industrial sectors. PMID:27531237

  19. 西方制造商售后服务战略研究述评%A Literature Review on After-Sales Strategies for Manufacturers in Western Countries

    Institute of Scientific and Technical Information of China (English)

    张辉

    2012-01-01

    Integrating literatures in marketing management,operation management,and logistics,this paper reviews and discusses the driving forces of an after-sales strategy,after-sales service portfolios design,pricing and distributing after-sales services and corresponding organizational changes bolstering the strategy,in hope that it can guide the manufacturers in China to formulate and implement the strategy.Last,this paper also illuminates the paths leading to future research.%综合营销管理、运营管理和物流管理等多个学科的研究成果,从售后服务战略的动因,售后服务组合设计、定价、渠道、制造商组织变革几个方面对西方现有研究成果进行了回顾和评述,以期对我国制造商售后服务战略的制定与实施有所启示。最后,还对未来研究进行了展望。

  20. Electrocardiogram-assisted blood pressure estimation.

    Science.gov (United States)

    Ahmad, Saif; Chen, Silu; Soueidan, Karen; Batkin, Izmail; Bolic, Miodrag; Dajani, Hilmi; Groza, Voicu

    2012-03-01

    Accurate automatic noninvasive assessment of blood pressure (BP) presents a challenge due to conditions like arrhythmias, obesity, and postural changes that tend to obfuscate arterial amplitude pulsations sensed by the cuff. Researchers tried to overcome this challenge by analyzing oscillometric pulses with the aid of a higher fidelity signal-the electrocardiogram (ECG). Moreover, pulse transit time (PTT) was employed to provide an additional method for BP estimation. However, these methods were not fully developed, suitably integrated, or tested. To address these issues, we present a novel method whereby ECG-assisted oscillometric and PTT (measured between ECG R-peaks and maximum slope of arterial pulse peaks) analyses are seamlessly integrated into the oscillometric BP measurement paradigm. The method bolsters oscillometric analysis (amplitude modulation) with more reliable ECG R-peaks provides a complementary measure with PTT analysis (temporal modulation) and fuses this information for robust BP estimation. We have integrated this technology into a prototype that comprises a BP cuff with an embedded conductive fabric ECG electrode, associated hardware, and algorithms. A pilot study has been undertaken on ten healthy subjects (150 recordings) to validate the performance of our prototype against United States Food and Drug Administration approved Omron oscillometric monitor (HEM-790IT). Our prototype achieves mean absolute difference of less than 5 mmHg and grade A as per the British Hypertension Society protocol for estimating BP, with the reference Omron monitor.