Sample records for bolsters

  1. Analysis of occurrence of malfunctions and deterioration of body bolster parts for gondola car

    Directory of Open Access Journals (Sweden)

    V.G. Anofriev


    Full Text Available All parts of a car frame and body are subject to a variable degree to corrosion deterioration but their most problematic part is a body bolster. The work on technical diagnosing of cars, operated more than 22 years, has given the chance to gain an impression on the frequency of occurrence of typical malfunctions, their dislocations and the degree of corrosion damages of the frame (car models 12-532 and 12-119 and can be used for forecasting their residual resource and constructive completion.

  2. Building a substitute model of a bolster based on experimentally determined deflection (United States)

    Zgoll, F.; Götze, T.; Volk, W.


    The high design requirements in the production of car body parts necessitate an exact closure of the forming tools in deep drawing processes. The tool closure is directly related to the machine elastic behaviour. To significantly reduce efforts and save time during ramp up of new forming tools, knowledge of the expected machine behaviour should be considered during the virtual development process of the tools. A prerequisite for that is building a validated machine-specific substitute model of the forming press composed of bolster, ram and drawing cushion. In this contribution, a substitute model with the help of finite element analysis (FEA) based on experimentally determined deflection is presented. The deflection measurements are performed by means of a multifunctional press measuring system from Volkswagen.

  3. Research and Teaching: Think before (and after) You Speak: Practice and Self-Reflection Bolster Oral Communication Skills (United States)

    Sterling, Eleanor; Bravo, Adriana; Porzecanski, Ana Luz; Burks, Romi L.; Linder, Joshua; Langen, Tom; Fernandez, Denny; Ruby, Douglas; Bynum, Nora


    In this study, conservation biology faculty and practitioners from across the United States designed classroom exercises and teaching interventions intended to bolster oral communication skills. Through repeated oral presentation assignments integrated into course requirements, the authors examined individual student learning gains via…

  4. Utilizing intraspecific variation in phenotypic plasticity to bolster agricultural and forest productivity under climate change. (United States)

    Aspinwall, Michael J; Loik, Michael E; Resco de Dios, Victor; Tjoelker, Mark G; Payton, Paxton R; Tissue, David T


    Climate change threatens the ability of agriculture and forestry to meet growing global demands for food, fibre and wood products. Information gathered from genotype-by-environment interactions (G × E), which demonstrate intraspecific variation in phenotypic plasticity (the ability of a genotype to alter its phenotype in response to environmental change), may prove important for bolstering agricultural and forest productivity under climate change. Nonetheless, very few studies have explicitly quantified genotype plasticity-productivity relationships in agriculture or forestry. Here, we conceptualize the importance of intraspecific variation in agricultural and forest species plasticity, and discuss the physiological and genetic factors contributing to intraspecific variation in phenotypic plasticity. Our discussion highlights the need for an integrated understanding of the mechanisms of G × E, more extensive assessments of genotypic responses to climate change under field conditions, and explicit testing of genotype plasticity-productivity relationships. Ultimately, further investigation of intraspecific variation in phenotypic plasticity in agriculture and forestry may prove important for identifying genotypes capable of increasing or sustaining productivity under more extreme climatic conditions. © 2014 John Wiley & Sons Ltd.

  5. Metacognitive Reflection as a Moderator of Attitude Strength Versus Attitude Bolstering: Implications for Attitude Similarity and Attraction. (United States)

    Sawicki, Vanessa; Wegener, Duane T


    "Strong" attitudes often have greater impact than "weak" attitudes. However, emerging research suggests that weak (uncertain) attitudes can substantially influence thinking or behavior. We propose metacognitive reflection as a moderator between traditional strength patterns and these emerging attitude bolstering patterns. Across six studies, research participants encountered a target person who agreed or disagreed with participants' attitudes. When focused on evaluating the target, attitudes predicted target evaluations better when the attitude was held with certainty (Study 1A), or after certainty had been primed (Studies 2A and 3; strength effects). However, when engaged in attitudinal social comparison (metacognitive reflection), attitudes better predicted target evaluation when the attitudes were held with doubt (Study 1B), or after doubt had been primed (Studies 2B and 3; bolstering effects). Expected change in certainty served as a mediator of attitude effects in metacognitive reflection but not target-focus conditions when doubt had been primed (Study 4).

  6. Use of a polytetrafluoroethylene (GORE-TEX) bolster to close the renal parenchymal defect during open partial nephrectomy. (United States)

    Redshaw, Jeffrey D; West, Jeremy M; Stephenson, Robert A; Lowrance, William T; Hamilton, Blake D; Southwick, Andrew W; Dechet, Christopher B


    Numerous surgical techniques have been described to facilitate closure of the renal parenchymal defect. We sought to describe the operative technique and define the safety and efficacy of using an expanded polytetrafluoroethylene (GORE-TEX; WL Gore and Associates, Flagstaff, AZ) bolster to aid in closure of the renal parenchymal defect at the time of open partial nephrectomy (OPN). A retrospective review of 175 patients who underwent an OPN using an expanded polytetrafluoroethylene (ePTFE) bolster at the Huntsman Cancer Hospital, University of Utah and Salt Lake City Veterans Affairs Medical Center from March 2005 to February 2013 was conducted. Postoperative complications occurring within 90 days were graded using the Clavien grading system. Overall, 57 patients (32.6%) experienced a postoperative complication. Fifteen patients (8.5%) had a Clavien ≥ grade-III complication. Ten patients (5.7%) received blood transfusions. Urine leak requiring intervention occurred in 2 patients (1.1%). Delayed hemorrhage requiring nephrectomy and pseudoaneurysm formation were rare, occurring in 1 patient each (0.6%). Infection of the ePTFE material occurred in 2 patients (1.1%). In both cases, it was explanted without requiring nephrectomy. The use of an ePTFE bolster is an effective and safe method of closing the renal parenchymal defect after OPN with an acceptable 90-day postoperative complication rate and a low risk of infection. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Immediate therapist self-disclosure bolsters the effect of brief integrative psychotherapy on psychiatric symptoms and the perceptions of therapists: A randomized clinical trial. (United States)

    Ziv-Beiman, Sharon; Keinan, Giora; Livneh, Elad; Malone, Patrick S; Shahar, Golan


    We report a first randomized clinical trial examining the effect of immediate and non-immediate therapist self-disclosure in the context of a brief integrative psychotherapy for mild to moderate distress. A total of 86 patients with mild to moderate forms of distress were randomly divided into three 12-session integrative psychotherapy conditions based primarily on [Hill, C. E. (2009). Helping skills: Facilitating, exploration, insight, and action (3rd ed.). Washington, DC: American Psychological Association.] three-stage model. Therapists trained in this treatment modality were instructed to use either immediate self-disclosure (expressing feelings towards the patient/treatment/therapeutic relationship) or non-immediate self-disclosure (expressing personal or factual information regarding the therapist's life outside the treatment). In the comparison condition, the therapists were instructed to refrain from self-disclosure altogether. Immediate therapist self-disclosure reduced psychiatric symptoms among patients with elevated pretreatment symptoms (as assessed by the Brief Symptoms Inventory) and bolstered a favorable perception of the therapist. Therapists in both the immediate and non-immediate self-disclosure group evaluated themselves more favorably than their counterparts in the non-disclosure group. Therapist self-disclosure, particularly of the immediate type, might enhance the effect of brief integrative treatment on psychiatric symptoms of high symptomatic patients and contribute to favorable perception of therapists.

  8. 1929 Dünya Ekonomi Krizi Ve Ulusal Ekonomiyi Güçlendirme Mücadelesinde Kadınlar The Impact Of 1929 World Economic Crisis On Turkey And Women In Bolstering National Economy

    Directory of Open Access Journals (Sweden)

    Doğan DUMAN


    Full Text Available After the independence war, Turkey went through some radicalpolitical and legal amendments. Despite the worst picture in economy,Turkey obtained significant successes as a result of the exuberance ofthe new Republic. However, the crisis which broke out first in the USAand then spread to the other capitalistic countries and which wasconsidered as the first major global crisis shook and had its deepreverberations in Turkey. The first impact was the devaluation of theTurkish currency. Secondly, the prices in theagriculture field droppedand affected the economy radically.Like many nations in a similar situation, Turkey planned toundergo a new economic policy and initiated a self sustaining policy.Hence, new measures were taken to encourage the nation to consumethe local products and to start saving. As a result, to implement thepolicy to use the local produce and to save as possible, a lot ofcampaigns were launched. Turkish women had a special mission in thisstruggle. Women who started to take their place sociallyandeconomically in the modernization process in Republic, had anactive role to bolster the national economy. This study aims athighlighting the major causes of the crisis, the impact on Turkisheconomy and the place of women in this struggle to overcome the crisis. Bağımsızlık savaşının kazanılmasından sonra Türkiye’de öncelikle köklü siyasal ve hukuksal değişiklikler gerçekleştirildi. Ekonomi alanında devralınan olumsuz tabloya rağmen ise, yeni bir devlet kurmanın verdiği coşkuyla ekonomik alanda da küçümsenmeyecek başarılar elde edildi. Fakat 1920’lerin sonunda önce Amerika Birleşik Devletleri’nde daha sonra diğer büyük kapitalist ülkelerde ortaya çıkan ve kapitalist dünyanın ilk büyük ekonomi krizi olarak nitelendirilen 1929 Dünya Ekonomi Krizi Türkiye’yi de derinden sarstı. Krizin Türkiye’ye ilk yansıması Türk lirasının hızlı bir değer kaybına uğraması şeklinde oldu. Ard

  9. Bolster Ground Force Capabilities in the Asia-Pacific Region (United States)


    this philosophy to its strategy of building a robust A2 /AD network by accelerating the modernization and capabilities of its force. By increasing the...region are the accelerated pace of China modernizing its People’s Liberation Army Navy (PLAN), increasing its anti-access/area-denial ( A2 /AD...capabilities, and escalating activity to expand territory in the South China Sea. With the rise of China as a maritime power and its increasing A2 /AD

  10. Russian energy in the EU market: Bolstered institutionsand their effects

    International Nuclear Information System (INIS)

    Romanova, Tatiana


    The article examines institutional changes in EU–Russian energy relations since 2000. The article explores the ability of transformed institutions to limit the politicisation of energy and to reconcile the EU competitive-market approach with Russian state capitalism. More specifically, the article focuses on changes in intergovernmental, transgovernmental and transnational interactions. The article demonstrates that the gradual strengthening of transgovernmental and transnational institutions has inhibited the politicisation of energy relations and facilitated regulative cooperation between the EU and Russia. However, the potential of shared institutions is constrained by internal institutions on both sides. In Russia, these obstacles are insufficient top-down delegation of responsibilities in the government and its great power aspirations. In the EU, key barriers include inter-institutional rivalries, the EU’s propensity to impose its legislation on external partners and the integration of energy policy with foreign policy. The article presents several policy implications. First, it is futile to institutionally impose the regulative paradigm of one partner on the other; rather, mutual dialogue is needed. Thus, institutions should be structured appropriately. Second, current depoliticisation will require the involvement of not only the EU and Russia but also transit countries, such as Ukraine. Third, transgovernmental and transnational cooperation should be nurtured because this is a useful channel for both information exchange and a regulative convergence of policy implementing mechanisms. Finally, this incremental regulative convergence is the only option available today for the EU and Russia; this is also a way to further depoliticise energy relations. - Highlights: • EU and Russia developed transgovernmental and transnational energy institutions. • It allowed them to face energy challenges: depoliticisation and market construction. • Internal EU and Russian institutions act as constraints. • Institutions have to marry Russia's state capitalism and EU competitive markets. • Transgovernmental and transnational institutions are to be further promoted

  11. Beyond "Autopsy Data": Bolstering Teacher Leadership, Morale, and School Improvement (United States)

    Sterrett, William; Irizarry, Eric


    Teacher working conditions surveys provide biennial, comprehensive data regarding school leadership. This case describes how a Title I middle school principal proactively addresses end-of-year data to address identified needs and growth areas in a collaborative manner in her middle school. The principal works in a concerted manner with an…

  12. Bolstering medical education to enhance critical care capacity in Cambodia. (United States)

    Albert, Tyler J; Fassier, Thomas; Chhuoy, Meng; Bounchan, Youttiroung; Tan, Sokhak; Ku, No; Chhor, Nareth; LoGerfo, James P; West, T Eoin


    The capacity to care for the critically ill has long been viewed as a fundamental element of established and comprehensive health care systems. Extending this capacity to health care systems in low- and middle-income countries is important given the burden of disease in these regions and the significance of critical care in overall health system strengthening. However, many practicalities of improving access and delivery of critical care in resource-limited settings have yet to be elucidated. We have initiated a program to build capacity for the care of critically ill patients in one low-income Southeast Asian country, Cambodia. We are leveraging existing international academic partnerships to enhance postgraduate critical care education in Cambodia. After conducting a needs assessment and literature review, we developed a three-step initiative targeting training in mechanical ventilation. First, we assessed and revised the current resident curriculum pertaining to mechanical ventilation. We addressed gaps in training, incorporated specific goals and learning objectives, and decreased the hours of lectures in favor of additional bedside training. Second, we are incorporating e-learning, e-teaching, and e-assessment into the curriculum, with both live, interactive and independent, self-paced online instruction. Third, we are developing a train-the-trainer program defined by bidirectional international faculty exchanges to provide hands-on, case-based, and bedside training to achieve competency-based outcomes. In targeting specific educational needs and a key population-the next generation of Cambodian intensivists-this carefully designed approach should address some existing gaps in the health care system and hopefully yield a lasting impact.

  13. V for Voice: Strategies for Bolstering Communication Skills in Statistics (United States)

    Khachatryan, Davit; Karst, Nathaniel


    With the ease and automation of data collection and plummeting storage costs, organizations are faced with massive amounts of data that present two pressing challenges: technical analysis of the data themselves and communication of the analytics process and its products. Although a plethora of academic and practitioner literature have focused on…

  14. States Launch High-Tech Program to Bolster Industrial Economy. (United States)

    Lepkowski, Wil


    Many states are establishing research centers keyed to universities strong in science and engineering as the Unites States' drive to become more technologically competitive shifts to the states. Initiatives in Ohio are provided as an example of this trend. (JN)

  15. Experience with the use of negative pressure bolster dressing for ...

    African Journals Online (AJOL)

    Methodology: This was a prospective study of consecutive patients from January 2009 to December 2010, with wounds over uneven and highly mobile anatomic regions that had their skin grafts stabilized using negative pressure wound dressing. Data on patients' age, sex, region of the body that was skin grafted, size of ...

  16. Update: Bolstering science journalism in the developing world ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    He has to write an article on education and human rights. However, the researchers refuse to disclose their information, because the journalist must submit a request in writing. He does so, but Chabi never receives a reply. SEE ALSO... Listen to science journalists reflect on the program's importance and discuss its ...

  17. Encouraging Spatial Talk: Using Children's Museums to Bolster Spatial Reasoning (United States)

    Polinsky, Naomi; Perez, Jasmin; Grehl, Mora; McCrink, Koleen


    Longitudinal spatial language intervention studies have shown that greater exposure to spatial language improves children's performance on spatial tasks. Can short naturalistic, spatial language interactions also evoke improved spatial performance? In this study, parents were asked to interact with their child at a block wall exhibit in a…

  18. France cuts its 'big science' spend to bolster lab research

    CERN Document Server

    McCabe, H


    French research agencies have been told by minister Allegre to cut FF200 million from their budgets for large scientific facilities to provide additi onal funds for laboratory research. The space agency CNES will absorb half of the cuts but the CNRS, LHC and Ganil will also be affected (1 page).

  19. POWERDRESS and diversified expression of the MIR172 gene family bolster the floral stem cell network.

    Directory of Open Access Journals (Sweden)

    Rae Eden Yumul

    Full Text Available Termination of the stem cells in the floral meristem (also known as floral determinacy is critical for the reproductive success of plants, and the molecular activities regulating floral determinacy are precisely orchestrated during the course of floral development. In Arabidopsis thaliana, regulators of floral determinacy include several transcription factor genes, such as APETALA2 (AP2, AGAMOUS (AG, SUPERMAN (SUP, and CRABSCLAW (CRC, as well as a microRNA (miRNA, miR172, which targets AP2. How the transcription factor and miRNA genes are coordinately regulated to achieve floral determinacy is unknown. A mutation in POWERDRESS (PWR, a previously uncharacterized gene encoding a SANT-domain-containing protein, was isolated in this study as an enhancer of the weakly indeterminate ag-10 allele. PWR was found to promote the transcription of CRC, MIR172a, b, and c and/or enhance Pol II occupancy at their promoters, without affecting MIR172d or e. A mutation in mature miR172d was additionally found to enhance the determinacy defects of ag-10 in an AP2-dependent manner, providing direct evidence that miR172d is functional in repressing AP2 and thereby contributes to floral determinacy. Thus, while PWR promotes floral determinacy by enhancing the expression of three of the five MIR172 members as well as CRC, MIR172d, whose expression is PWR-independent, also functions in floral stem cell termination. Taken together, these findings demonstrate how transcriptional diversification and functional redundancy of a miRNA family along with PWR-mediated co-regulation of miRNA and transcription factor genes contribute to the robustness of the floral determinacy network.

  20. 3D map of Universe bolsters case for dark energy and dark matter

    CERN Multimedia


    "Astronomers from the Sloan Digital Sky Survey (SDSS) have made the most precise measurement to date of the cosmic clustering of galaxies and dark matter, refining our understanding of the structure and evolution of the Universe" (1 page).

  1. Maintaining the system with tokenism: bolstering individual mobility beliefs and identification with a discriminatory organization. (United States)

    Danaher, Kelly; Branscombe, Nyla R


    Two experiments examined the effects of gender-based token hiring practices in organizational settings. In Expt 1, women were exposed to organizational hiring practices that were open, token, or closed. Token practices served to perpetuate inequality by maintaining individual mobility beliefs and organizational identification. In Expt 2, both men and women imagined working for a corporation that planned to implement open, token, or closed hiring practices. Although women reported experiencing negative emotions in the closed and token conditions compared to the open condition, token practices maintained positive perceptions of the organization and individual mobility beliefs compared to the closed condition. Men endorsed more individual mobility beliefs as well as positive emotions in the token and closed conditions compared to the open condition. Token practices distort perceptions of fairness in both women and men. For women, token practices make group boundaries seem more negotiable than they actually are, while for men token practices legitimize their group's dominance.



    Aregamalage Sujeewa Vijayanthi Polgampala; Fang Huang


    The importance of good teachers is no secret. Over the last two decades, research on student achievement has pinpointed the central role of teachers as one of the key propellers referred to in terms of a focus on student outcomes. This review exploits the teacher’s effectiveness and what makes an effective teacher. Classroom management, classroom climate and teaching are the three factors that had statistically significant positive impacts on student academic outcomes. Teachers’ sense of prof...

  3. Does more energy consumption bolster economic growth? An application of the nonlinear threshold regression model

    International Nuclear Information System (INIS)

    Huang, B.-N.; Hwang, M.J.; Yang, C.W.


    This paper separates data extending from 1971 to 2002 into the energy crisis period (1971-1980) and the post-energy crisis period (1981-2000) for 82 countries. The cross-sectional data (yearly averages) in these two periods are used to investigate the nonlinear relationships between energy consumption growth and economic growth when threshold variables are used. If threshold variables are higher than certain optimal threshold levels, there is either no significant relationship or else a significant negative relationship between energy consumption and economic growth. However, when these threshold variables are lower than certain optimal levels, there is a significant positive relationship between the two. In 48 out of the 82 countries studied, none of the four threshold variables is found to be higher than the optimal levels. It is inferred that these 48 countries should adopt a more aggressive energy policy. As for the other 34 countries, at least one threshold variable is higher than the optimal threshold level and thus these countries should adopt energy policies with varying degrees of conservation based on the number of threshold variables that are higher than the optimal threshold levels

  4. Oregonians Debate Whether to Use Tax Funds to Bolster the State Universities' Flagging Sports Programs. (United States)

    Lederman, Douglas


    Rising program deficits and lack of state aid for college sports programs in Oregon have caused the suspension of sports teams as a cost-cutting measure. Some trace the financial problems to equalization of women's sports and the 1982 downturn in the lumber industry. Financing options appear limited. (MSE)

  5. Increasing Neuroplasticity to Bolster Chronic Pain Treatment: A Role for Intermittent Fasting and Glucose Administration? (United States)

    Sibille, KT; Bartsch, F; Reddy, D; Fillingim, RB; Keil, A


    Neuroplastic changes in brain structure and function are not only a consequence of chronic pain but are involved in the maintenance of pain symptoms. Thus, promoting adaptive, treatment responsive neuroplasticity represents a promising clinical target. Emerging evidence about the human brain’s response to an array of behavioral and environmental interventions may assist in identifying targets to facilitate increased neurobiological receptivity, promoting healthy neuroplastic changes. Specifically, strategies to maximize neuroplastic responsiveness to chronic pain treatment could enhance treatment gains by optimizing learning and positive central nervous system (CNS) adaptation. Periods of heightened plasticity have been traditionally identified with the early years of development. More recent research however has identified a wide spectrum of methods that can be used to “re-open” and enhance plasticity and learning in adults. In addition to transcranial direct current stimulation and transcranial magnetic stimulation, behavioral and pharmacological interventions have been investigated. Intermittent fasting and glucose administration are two propitious strategies, which are non-invasive, inexpensive to administer, implementable in numerous settings, and may be applicable across differing chronic pain treatments. Key findings and neurophysiological mechanisms are summarized, providing evidence for the potential clinical contributions of these two strategies toward ameliorating chronic pain. PMID:26848123

  6. Increasing Neuroplasticity to Bolster Chronic Pain Treatment: A Role for Intermittent Fasting and Glucose Administration? (United States)

    Sibille, Kimberly T; Bartsch, Felix; Reddy, Divya; Fillingim, Roger B; Keil, Andreas


    Neuroplastic changes in brain structure and function are not only a consequence of chronic pain but are involved in the maintenance of pain symptoms. Thus, promotion of adaptive, treatment-responsive neuroplasticity represents a promising clinical target. Emerging evidence about the human brain's response to an array of behavioral and environmental interventions may assist in identifying targets to facilitate increased neurobiological receptivity, promoting healthy neuroplastic changes. Specifically, strategies to maximize neuroplastic responsiveness to chronic pain treatment could enhance treatment gains by optimization of learning and positive central nervous system adaptation. Periods of heightened plasticity have been traditionally identified with the early years of development. More recent research, however, has identified a wide spectrum of methods that can be used to "reopen" and enhance plasticity and learning in adults. In addition to transcranial direct current stimulation and transcranial magnetic stimulation, behavioral and pharmacological interventions have been investigated. Intermittent fasting and glucose administration are two propitious strategies, that are noninvasive, inexpensive to administer, implementable in numerous settings, and might be applicable across differing chronic pain treatments. Key findings and neurophysiological mechanisms are summarized, and evidence for the potential clinical contributions of these two strategies toward ameliorating chronic pain is presented. Neuroplastic changes are a defining feature of chronic pain and a complicating factor in treatment. Noninvasive strategies to optimize the brain's response to treatment interventions might improve learning and memory, increase the positive adaptability of the central nervous system, and enhance treatment outcomes. Copyright © 2016 American Pain Society. Published by Elsevier Inc. All rights reserved.

  7. Bolstering resilience in the coconut kingdom: Improving adaptive capacity to climate change in Vanuatu

    International Nuclear Information System (INIS)

    Richmond, Noah; Sovacool, Benjamin K.


    This communication discusses climate change adaptation efforts underway in Vanuatu. In particular, it uncovers why community-based approaches to adaptation are more likely to bear fruit than ones driven from the top-down at the national level. The authors make this claim based on early evidence that small-scale projects (a) support community ownership over adaptation, (b) provide ongoing technical learning lessons (c) relieve pressure from capacity constraints at national administrative bodies, and (d) expedite implementation by avoiding cumbersome multilateral procedures. The first section discusses its research methods and presents important characteristics of the Vanuatu economy, people and geography. The communication then moves on to discuss Vanuatu’s vulnerability to the effects of climate change. It specifically investigates on-going efforts to adapt to natural climatic hazards in Vanuatu. Early evidence and analysis reveals lessons salient for energy and climate policy. - Highlights: ► The island state of Vanuatu is especially vulnerable to natural climatic hazards and climate change. ► Community-based approaches to climate change adaptation have unique benefits in Vanuatu. ► This note provides lessons salient for energy and climate policy in Vanuatu.

  8. S. mansoni bolsters anti-viral immunity in the murine respiratory tract.

    Directory of Open Access Journals (Sweden)

    Sebastian Scheer

    Full Text Available The human intestinal parasite Schistosoma mansoni causes a chronic disease, schistosomiasis or bilharzia. According to the current literature, the parasite induces vigorous immune responses that are controlled by Th2 helper cells at the expense of Th1 helper cells. The latter cell type is, however, indispensable for anti-viral immune responses. Remarkably, there is no reliable literature among 230 million patients worldwide describing defective anti-viral immune responses in the upper respiratory tract, for instance against influenza A virus or against respiratory syncitial virus (RSV. We therefore re-examined the immune response to a human isolate of S. mansoni and challenged mice in the chronic phase of schistosomiasis with influenza A virus, or with pneumonia virus of mice (PVM, a mouse virus to model RSV infections. We found that mice with chronic schistosomiasis had significant, systemic immune responses induced by Th1, Th2, and Th17 helper cells. High serum levels of TNF-α, IFN-γ, IL-5, IL-13, IL-2, IL-17, and GM-CSF were found after mating and oviposition. The lungs of diseased mice showed low-grade inflammation, with goblet cell hyperplasia and excessive mucus secretion, which was alleviated by treatment with an anti-TNF-α agent (Etanercept. Mice with chronic schistosomiasis were to a relative, but significant extent protected from a secondary viral respiratory challenge. The protection correlated with the onset of oviposition and TNF-α-mediated goblet cell hyperplasia and mucus secretion, suggesting that these mechanisms are involved in enhanced immune protection to respiratory viruses during chronic murine schistosomiasis. Indeed, also in a model of allergic airway inflammation mice were protected from a viral respiratory challenge with PVM.

  9. Incidental Learning of Rewarded Associations Bolsters Learning on an Associative Task (United States)

    Freedberg, Michael; Schacherer, Jonathan; Hazeltine, Eliot


    Reward has been shown to change behavior as a result of incentive learning (by motivating the individual to increase their effort) and instrumental learning (by increasing the frequency of a particular behavior). However, Palminteri et al. (2011) demonstrated that reward can also improve the incidental learning of a motor skill even when…

  10. Better BAT to Bolster Ecosystem Resilience : Operationalizing Ecological Governance through the Concept of Best Available Techniques

    NARCIS (Netherlands)

    Giljam, Renske A.

    This article examines to what extent ecological governance can be implemented by extending the concept of Best Available Techniques (BAT) at the European Union level. It therefore firstly analyses what ecological governance would require and what this implies for employing the use of BAT. The

  11. Networking of Public Health Microbiology Laboratories Bolsters Europe’s Defenses against Infectious Diseases

    Directory of Open Access Journals (Sweden)

    Barbara Albiger


    Full Text Available In an era of global health threats caused by epidemics of infectious diseases and rising multidrug resistance, microbiology laboratories provide essential scientific evidence for risk assessment, prevention, and control. Microbiology has been at the core of European infectious disease surveillance networks for decades. Since 2010, these networks have been coordinated by the European Centre for Disease Prevention and Control (ECDC. Activities delivered in these networks include harmonization of laboratory diagnostic, antimicrobial susceptibility and molecular typing methods, multicentre method validation, technical capacity mapping, training of laboratory staff, and continuing quality assessment of laboratory testing. Cooperation among the European laboratory networks in the past 7 years has proved successful in strengthening epidemic preparedness by enabling adaptive capabilities for rapid detection of emerging pathogens across Europe. In partnership with food safety authorities, international public health agencies and learned societies, ECDC-supported laboratory networks have also progressed harmonization of routinely used antimicrobial susceptibility and molecular typing methods, thereby significantly advancing the quality, comparability and precision of microbiological information gathered by ECDC for surveillance for zoonotic diseases and multidrug-resistant pathogens in Europe. ECDC continues to act as a catalyst for sustaining continuous practice improvements and strengthening wider access to laboratory capacity across the European Union. Key priorities include optimization and broader use of rapid diagnostics, further integration of whole-genome sequencing in surveillance and electronic linkage of laboratory and public health systems. This article highlights some of the network contributions to public health in Europe and the role that ECDC plays managing these networks.

  12. Bolstering the Evidence Base for Integrating Abortion and HIV Care: A Literature Review

    Directory of Open Access Journals (Sweden)

    Ruth Manski


    Full Text Available HIV-positive women have abortions at similar rates to their HIV-negative counterparts, yet little is known about clinical outcomes of abortion for HIV-positive women or the best practices for abortion provision. To fill that gap, we conducted a literature review of clinical outcomes of surgical and medication abortion among HIV-positive women. We identified three studies on clinical outcomes of surgical abortion among HIV-positive women; none showed significant differences in infectious complications by HIV status. A review of seven articles on similar gynecological procedures found no differences in complications by HIV status. No studies evaluated medication abortion among HIV-positive women. However, we did find that previously expressed concerns regarding blood loss and vomiting related to medication abortion for HIV-positive women are unwarranted based on our review of data showing that significant blood loss and vomiting are rare and short lived among women. We conclude that although there is limited research that addresses clinical outcomes of abortion for HIV-positive women, existing data suggest that medication and surgical abortion are safe and appropriate. Sexual and reproductive health and HIV integration efforts must include both options to prevent maternal mortality and morbidity and to ensure that HIV-positive women and women at risk of HIV can make informed reproductive decisions.

  13. Bolstering Immunity through Pattern Recognition Receptors: A Unique Approach to Control Tuberculosis

    Directory of Open Access Journals (Sweden)

    Susanta Pahari


    Full Text Available The global control of tuberculosis (TB presents a continuous health challenge to mankind. Despite having effective drugs, TB still has a devastating impact on human health. Contributing reasons include the emergence of drug-resistant strains of Mycobacterium tuberculosis (Mtb, the AIDS-pandemic, and the absence of effective vaccines against the disease. Indeed, alternative and effective methods of TB treatment and control are urgently needed. One such approach may be to more effectively engage the immune system; particularly the frontline pattern recognition receptor (PRR systems of the host, which sense pathogen-associated molecular patterns (PAMPs of Mtb. It is well known that 95% of individuals infected with Mtb in latent form remain healthy throughout their life. Therefore, we propose that clues can be found to control the remainder by successfully manipulating the innate immune mechanisms, particularly of nasal and mucosal cavities. This article highlights the importance of signaling through PRRs in restricting Mtb entry and subsequently preventing its infection. Furthermore, we discuss whether this unique therapy employing PRRs in combination with drugs can help in reducing the dose and duration of current TB regimen.

  14. Using the Think-Aloud Strategy to Bolster Reading Comprehension of Science Concepts (United States)

    Ortlieb, Evan; Norris, Megan


    Comprehension of text is developmental in that it begins with a child's ability to listen and make sense of language. Though listening comprehension is often the predecessor towards reading comprehension; some children maintain difficulties in listening comprehension throughout schooling and into adulthood. This quasi-experimental study…

  15. When Science Replaces Religion: Science as a Secular Authority Bolsters Moral Sensitivity. (United States)

    Yilmaz, Onurcan; Bahçekapili, Hasan G


    Scientific and religious thinking compete with each other on several levels. For example, activating one generally weakens the other. Since priming religion is known to increase moral behaviour and moral sensitivity, priming science might be expected to have the opposite effect. However, it was recently demonstrated that, on the contrary, science priming increases moral sensitivity as well. The present set of studies sought to replicate this effect and test two explanations for it. Study 1 used a sentence unscrambling task for implicitly priming the concept of science but failed to replicate its effect on moral sensitivity, presumably due to a ceiling effect. Study 2 replicated the effect with a new measure of moral sensitivity. Study 3 tested whether science-related words create this effect by activating the idea of secular authority or by activating analytic thinking. It was demonstrated that words related to secular authority, but not words related to analytic thinking, produced a similar increase in moral sensitivity. Religiosity level of the participants did not influence this basic finding. The results are consistent with the hypothesis that science as a secular institution has overtaken some of the functions of religion in modern societies.

  16. Effect of Welding on the Notch Toughness of a Casualty Material (280mm Carriage Number 60 Rear Float Bolster), (United States)

    Gun mounts, * Steel , Mechanical properties, Welds, Welding, Notch toughness, Charpy impact tests , Brittleness, Fracture(Mechanics), Subarctic regions, Low temperature, Test methods, Tension, Flanges

  17. Better Patient Care At High-Quality Hospitals May Save Medicare Money And Bolster Episode-Based Payment Models. (United States)

    Tsai, Thomas C; Greaves, Felix; Zheng, Jie; Orav, E John; Zinner, Michael J; Jha, Ashish K


    US policy makers are making efforts to simultaneously improve the quality of and reduce spending on health care through alternative payment models such as bundled payment. Bundled payment models are predicated on the theory that aligning financial incentives for all providers across an episode of care will lower health care spending while improving quality. Whether this is true remains unknown. Using national Medicare fee-for-service claims for the period 2011-12 and data on hospital quality, we evaluated how thirty- and ninety-day episode-based spending were related to two validated measures of surgical quality-patient satisfaction and surgical mortality. We found that patients who had major surgery at high-quality hospitals cost Medicare less than those who had surgery at low-quality institutions, for both thirty- and ninety-day periods. The difference in Medicare spending between low- and high-quality hospitals was driven primarily by postacute care, which accounted for 59.5 percent of the difference in thirty-day episode spending, and readmissions, which accounted for 19.9 percent. These findings suggest that efforts to achieve value through bundled payment should focus on improving care at low-quality hospitals and reducing unnecessary use of postacute care. Project HOPE—The People-to-People Health Foundation, Inc.

  18. A finite element lower extremity and pelvis model for predicting bone injuries due to knee bolster loading

    NARCIS (Netherlands)

    Rooij, L. van; Hoof, J. van; Barbir, A.; Made, R. van der; Slaats, P.M.A.; McCann, M.J.; Ridella, S.A.; Rupp, J.D.


    Injuries to the knee-thigh-hip (KTH) complex in frontal motor vehicle crashes are of substantial concern because of their frequency and potential to result in long-term disability. Current frontal impact Anthropometric Test Dummies (ATDs) have been shown to respond differently than human cadavers

  19. A Brief Intervention to Bolster a 5th Grader's Regrouping Skills in Math (United States)

    Waugh, Matthew; Harrison, Gina L.


    This study examined the efficacy of a brief math intervention using cognitive behaviour instruction (CBI) supplemented by a mnemonic cue system for a 5th grade student with math computation and fluency difficulties. Regrouping operations in addition and subtraction were the targeted skills. Curriculum-based measurements were conducted at the end…

  20. Assortative and dissortative priorities for game interaction and strategy adaptation significantly bolster network reciprocity in the prisoner’s dilemma

    International Nuclear Information System (INIS)

    Tanimoto, Jun


    In 2 × 2 prisoner’s dilemma games, network reciprocity is one mechanism for adding social viscosity, which leads to cooperative equilibrium. Here we show that combining the process for selecting a gaming partner with the process for selecting an adaptation partner significantly enhances cooperation, even though such selection processes require additional costs to collect further information concerning which neighbor should be chosen. Based on elaborate investigations of the dynamics generated by our model, we find that high levels of cooperation result from two kinds of behavior: cooperators tend to interact with cooperators to prevent being exploited by defectors and defectors tend to choose cooperators to exploit despite the possibility that some defectors convert to cooperators. (paper)

  1. Global representation of threatened amphibians ex situ is bolstered by non-traditional institutions, but gaps remain

    DEFF Research Database (Denmark)

    Biega, A; Greenberg, D.A.; Mooers, A.O.


    priority by testing how eight variables relating to extinction risk – International Union for the Conservation of Nature status, habitat specialization, obligate stream breeding, geographic range size, body size and island, high-altitude and tropical endemism – vary between amphibian species held in zoos...... greater overall extinction risk in the near future. We strongly encourage zoos to continue increasing their holdings of amphibian species, but to pay greater attention to these species of particular conservation concern....

  2. Cancer screening and health system resilience: keys to protecting and bolstering preventive services during a financial crisis. (United States)

    Martin-Moreno, Jose M; Anttila, Ahti; von Karsa, Lawrence; Alfonso-Sanchez, Jose L; Gorgojo, Lydia


    The aim of this paper is to elucidate the rationale for sustaining and expanding cost-effective, population-based screening services for breast, cervical and colorectal cancers in the context of the current financial crisis. Our objective is not only to promote optimal delivery of high-quality secondary cancer prevention services, but also to underline the importance of strengthening comprehensive cancer control, and with it, health system response to the complex care challenges posed by all chronic diseases. We focus primarily on issues surrounding planning, organisation, implementation and resources, arguing that given the growing cancer burden, policymakers have ample justification for establishing and expanding population-based programmes that are well-organised, well-resourced and well-executed. In a broader economic context of rescue packages, deficits and cutbacks to government entitlements, health professionals must intensify their advocacy for the protection of vital preventive health services by fighting for quality services with clear benefits for population health outcomes. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Increasing the Chances of Implementing NGSS by Bolstering High School Teacher Knowledge and Views about Climate Change, a NICE NASA Example (United States)

    Bleicher, R. E.


    Purpose of Presentation This paper will highlight how the results of this initial study foreshadow possibilities of NGSS (NGSS, 2013) playing out in high school classrooms in the near future. Research findings from a three-year NASA-funded project, Promoting Educational Leadership in Climate Science (PEL) will be presented. Objectives and Research Questions PEL aims to increase climate science literacy in high school teachers and students through scientific argumentation using authentic NASA data. This initial study focuses on the following questions: 1. Are teachers increasing their climate science knowledge? 2. Are there changes in teachers' views about climate change? 3. What resources and are provided to assist teachers to develop their students' scientific argumentation skills? Theoretical Framework Because of the changing nature of climate science knowledge and its relevance to societal issues, teachers must be able to understand the basic concepts and remain up-to-date on scientific issues. The need for a more thorough understanding of the concepts of climate change are highlighted by recent studies on the public perceptions and attitudes on the subject (Leiserowitz et al., 2013). Teachers need to understand the difference between skepticism as a characteristic of the nature of science and denial of climate change (Sommervillle & Hasol, 2011). Teachers need to understand the natural and human-induced factors affecting climate, and the potential consequences, and ways to mitigate and adapt to climate change. Generally, when teachers learn about a subject, they demonstrate more self-efficacy to teach about it (Bleicher & Lindgren, 2005). Analytic Strategy Data were analyzed using paired-samples t-tests, independent t -tests, and ANOVA. Latent class analysis was employed to analyze the Six America's Survey data. Correlational studies were conducted to examine possible relationships among variables. Findings in Brief Teachers' content knowledge increased significantly and teachers were more concerned about climate change after participation in PEL. Teachers with higher self-efficacy demonstrated higher climate change science knowledge. Teachers indicated that they felt more confident and were motivated to implement classroom lessons with their students that employed resources rich in NASA climate data and focused on scientific argumentation. References Bleicher, R.E., & Lindgren, J. (2005). Success in learning science and preservice science teaching self-efficacy. Journal of Science Teacher Education. 16, 205-225. Leiserowitz, A., Maibach, E., Roser-Renouf, C., Feinberg, G., & Howe, P.(2013) Climate change in the American mind: Americans' global warming beliefs and attitudes in April, 2013 Yale University and George Mason University. New Haven, CT: Yale Project on Climate Change Communication. Retrieved 7/26/13 from: Next Generation Science Standards (NGSS). (2013). Available at Somerville, R. C. J. & Hassol, S. J. (2011). Communicating the science of climate change. Physics Today, 64(10), 48-53.

  4. An interdisciplinary palliative rehabilitation intervention bolstering general self-efficacy to attenuate symptoms of depression in patients living with advanced cancer. (United States)

    Feldstain, A; Lebel, S; Chasen, M R


    Patients with advanced cancer, post-anticancer treatment, are living longer than 10-20 years ago. This emerging population of survivors has unique palliative and rehabilitation needs. A particular concern is depression, which can impair functioning, quality of life, and survival. The interdisciplinary Palliative Rehabilitation Program offers holistic palliative rehabilitation for this population using a self-efficacy framework. The current study examined the unique impact of three program factors that have been shown to improve depression: inflammation, exercise, and self-efficacy. Patients underwent a 2-month interdisciplinary intervention (up to six disciplines) and thorough pre-post assessments. Measures included serum C-reactive protein, 6-min walk test, General Self-efficacy Scale, and Hospital Anxiety and Depression Scale (depression subscale). Paired t tests analyzed pre-post changes in each variable, and a hierarchical linear regression analyzed the predictors' unique contributions of changes in depression in this quasi-experimental design. The sample included 80 patients (52.5% females), with stages 3/4 heterogeneous cancers. Results revealed that C-reactive protein (CRP) did not significantly change pre-post, from 7.39 (SD = 11.99) to 9.47 mg/L (SD = 16.41), p = 0.110, exercise significantly increased, from 372.55 (SD = 137.71) to 412.64 m (SD = 144.31), p self-efficacy significantly increased from 27.86 (SD = 6.16) to 31.23 units (SD = 5.77), p self-efficacy accounted for 11% of change in depression scores (p self-efficacy framework may be a helpful ingredient in interdisciplinary intervention to decrease depressive symptomatology.

  5. The Ca2+/calmodulin2-binding transcription factor TGA3 elevates LCD expression and H2S production to bolster Cr6+tolerance in Arabidopsis. (United States)

    Fang, Huihui; Liu, Zhiqiang; Long, Yanping; Liang, Yali; Jin, Zhuping; Zhang, Liping; Liu, Danmei; Li, Hua; Zhai, Jixian; Pei, Yanxi


    Heavy metal (HM) contamination on agricultural land not only reduces crop yield but also causes human health concerns. As a plant gasotransmitter, hydrogen sulfide (H 2 S) can trigger various defense responses and help reduce accumulation of HMs in plants; however, little is known about the regulatory mechanisms of H 2 S signaling. Here, we provide evidence to answer the long-standing question about how H 2 S production is elevated in the defense of plants against HM stress. During the response of Arabidopsis to chromium (Cr 6+ ) stress, the transcription of L-cysteine desulfhydrase (LCD), the key enzyme for H 2 S production, was enhanced through a calcium (Ca 2+ )/calmodulin2 (CaM2)-mediated pathway. Biochemistry and molecular biology studies demonstrated that Ca 2+ /CaM2 physically interacts with the bZIP transcription factor TGA3, a member of the 'TGACG'-binding factor family, to enhance binding of TGA3 to the LCD promoter and increase LCD transcription, which then promotes the generation of H 2 S. Consistent with the roles of TGA3 and CaM2 in activating LCD expression, both cam2 and tga3 loss-of-function mutants have reduced LCD abundance and exhibit increased sensitivity to Cr 6+ stress. Accordingly, this study proposes a regulatory pathway for endogenous H 2 S generation, indicating that plants respond to Cr 6+ stress by adjusting the binding affinity of TGA3 to the LCD promoter, which increases LCD expression and promotes H 2 S production. This suggests that manipulation of the endogenous H 2 S level through genetic engineering could improve the tolerance of grains to HM stress and increase agricultural production on soil contaminated with HMs. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

  6. Effect of a Counseling Session Bolstered by Text Messaging on Self-Selected Health Behaviors in College Students: A Preliminary Randomized Controlled Trial. (United States)

    Sandrick, Janice; Tracy, Doreen; Eliasson, Arn; Roth, Ashley; Bartel, Jeffrey; Simko, Melanie; Bowman, Tracy; Harouse-Bell, Karen; Kashani, Mariam; Vernalis, Marina


    The college experience is often the first time when young adults live independently and make their own lifestyle choices. These choices affect dietary behaviors, exercise habits, techniques to deal with stress, and decisions on sleep time, all of which direct the trajectory of future health. There is a need for effective strategies that will encourage healthy lifestyle choices in young adults attending college. This preliminary randomized controlled trial tested the effect of coaching and text messages (short message service, SMS) on self-selected health behaviors in the domains of diet, exercise, stress, and sleep. A second analysis measured the ripple effect of the intervention on health behaviors not specifically selected as a goal by participants. Full-time students aged 18-30 years were recruited by word of mouth and campuswide advertisements (flyers, posters, mailings, university website) at a small university in western Pennsylvania from January to May 2015. Exclusions included pregnancy, eating disorders, chronic medical diagnoses, and prescription medications other than birth control. Of 60 participants, 30 were randomized to receive a single face-to-face meeting with a health coach to review results of behavioral questionnaires and to set a health behavior goal for the 8-week study period. The face-to-face meeting was followed by SMS text messages designed to encourage achievement of the behavioral goal. A total of 30 control subjects underwent the same health and behavioral assessments at intake and program end but did not receive coaching or SMS text messages. The texting app showed that 87.31% (2187/2505) of messages were viewed by intervention participants. Furthermore, 28 of the 30 intervention participants and all 30 control participants provided outcome data. Among intervention participants, 22 of 30 (73%) showed improvement in health behavior goal attainment, with the whole group (n=30) showing a mean improvement of 88% (95% CI 39-136). Mean improvement in any behavioral domains was not seen in the control group. Intervention participants also increased their exercise significantly compared with controls, regardless of their self-selected goal category. The increased exercise was paralleled by significantly lower fasting glucose levels. The health coaching session plus tailored SMS text messages improved self-selected health behaviors with a modest ripple effect to include unselected health behaviors. NCT02476604; (Archived by WebCite at ©Janice Sandrick, Doreen Tracy, Arn Eliasson, Ashley Roth, Jeffrey Bartel, Melanie Simko, Tracy Bowman, Karen Harouse-Bell, Mariam Kashani, Marina Vernalis. Originally published in JMIR Mhealth and Uhealth (, 17.05.2017.

  7. DARWARS Integration Plan: A BBN Technologies Document, Version 2.0

    National Research Council Canada - National Science Library


    .... In the DARWARS vision, current personal computer technology, bolstered by the commercial successes of the massively multiplayer game market, will support a revolution in computer-based training...

  8. Redevelopment Ready Communities: Best Practices and Scoring System (United States)

    This report discusses the Redevelopment Ready Communities program in southeast Michigan, which encourages mature suburbs to bolster their competitiveness by making development more efficient and less complicated.

  9. How to Be Happy: Tips for Cultivating Contentment (United States)

    ... a goal provides a sense of purpose, bolsters self-esteem and brings people together. What your goal is ... fluctuating happiness to authentic-durable happiness. Frontiers in Psychology. 2012;3:16. Miron-Shatz T, et al. ...

  10. 76 FR 11395 - Reducing Regulatory Burden; Retrospective Review Under E.O. 13563 (United States)


    ... range of individuals and families with special needs, including homeless individuals, the elderly, and... rulemaking initiatives to strengthen the housing market to bolster the economy and protect consumers. B...

  11. Working with numbers and statistics a handbook for journalists

    CERN Document Server

    Livingston, Charles


    Working With Numbers and Statistics: A Handbook for Journalists will bolster math skills and improve math confidence for journalists at all skill levels. Authors Charles Livingston and Paul Voakes developed this resource book to improve journalist

  12. 21 CFR 878.4930 - Suture retention device. (United States)


    ... button, or a suture bolster, intended to aid wound healing by distributing suture tension over a larger area in the patient. (b) Classification. Class I (general controls). The device is exempt from the...

  13. Have You Considered Gamifying Your Classroom? (United States)

    Glass, Graham


    New classroom practices can be brought into the classroom that engage students through their enjoyment of games, while building their confidence and bolstering their understanding that mistakes are valuable stops along the journey to understanding.

  14. Armenia, Azerbaijan, and Georgia: Security Issues and Implications for U.S. Interests

    National Research Council Canada - National Science Library

    Nichol, Jim


    .... The regional governments have worked to bolster their security by combating terrorism, limiting political dissent they view as threatening, revamping their armed forces, and seeking outside assistance and allies...

  15. A Heuristic Algorithm for U.S. Naval Mission Resource Allocation

    National Research Council Canada - National Science Library

    Dwyer, Derek T


    Current military leadership is directing the U.S. Navy to engage in theater security cooperation activities or missions to bolster confidence and build trust relationships with other national military forces...

  16. Further Fossil finds from Flores


    Lieberman, Daniel Eric


    New fossil discoveries on Flores, Indonesia, bolster the evidence that Homo floresiensiswas a dwarfed human species that lived at the end of the last ice age. But the species’ evolutionary origins remain obscure.

  17. Optimizing Processes to Minimize Risk (United States)

    Loyd, David


    NASA, like the other hazardous industries, has suffered very catastrophic losses. Human error will likely never be completely eliminated as a factor in our failures. When you can't eliminate risk, focus on mitigating the worst consequences and recovering operations. Bolstering processes to emphasize the role of integration and problem solving is key to success. Building an effective Safety Culture bolsters skill-based performance that minimizes risk and encourages successful engagement.

  18. Special Inspector General for Iraq Reconstruction, Quarterly Report to the United States Congress (United States)


    domestic and foreign partnerships. Status: Inma supported a maize -production project in Anbar province, introducing new varieties of maize to bolster...and foreign partnerships. Status: Inma supported a maize -production project in Anbar province, introducing new varieties of maize to bolster the...and supports commodity -focused agribusinesses, complementing the activities of the U.S. Depart- ment of Agriculture.167 These efforts are aimed at

  19. 77 FR 20485 - Notice of Receipt of Petition for Decision That Nonconforming 1999 to 2006 Toyota Land Cruiser... (United States)


    ... equipped. Standard No. 206 Door Locks and Door Retention Components: inspection of each vehicle and replacement of non U.S.-model door lock components with U.S.-model components on vehicles that are not already... automatic restraint system that consists of dual front air bags and knee bolsters. In addition, the vehicles...

  20. Identification of Factors Contributing to Gender Disparity in an ...

    African Journals Online (AJOL)

    in absolute numbers while female dismissal rates soared alarmingly between 2000/01-2004/05. To bridge the gender disparity in participation, the paper recommends intervention strategies aimed at bolstering academic achievement and positive self-concept among female students. East African Social Science Research ...

  1. Science Production in Germany, France, Belgium, and Luxembourg: Comparing the Contributions of Research Universities and Institutes to Science, Technology, Engineering, Mathematics, and Health (United States)

    Powell, Justin J. W.; Dusdal, Jennifer


    Charting significant growth in science production over the 20th century in four European Union member states, this neo-institutional analysis describes the development and current state of universities and research institutes that bolster Europe's position as a key region in global science. On-going internationalization and Europeanization of…

  2. Biodemography of human ageing

    DEFF Research Database (Denmark)

    Vaupel, James W


    Human senescence has been delayed by a decade. This finding, documented in 1994 and bolstered since, is a fundamental discovery about the biology of human ageing, and one with profound implications for individuals, society and the economy. Remarkably, the rate of deterioration with age seems...

  3. 49 CFR 229.65 - Spring rigging. (United States)


    ... 49 Transportation 4 2010-10-01 2010-10-01 false Spring rigging. 229.65 Section 229.65....65 Spring rigging. (a) Protective construction or safety hangers shall be provided to prevent spring planks, spring seats or bolsters from dropping to track structure in event of a hanger or spring failure...

  4. Unpacking Biases: Developing Cultural Humility in Early Childhood and Elementary Teacher Candidates (United States)

    Brown, Elizabeth Levine; Vesely, Colleen K.; Dallman, Laura


    Changing demographics in the U.S. require a focus on educating future teachers on how to engage children and families with diverse backgrounds. Teacher educators have been charged to address teachers' cultural competence and provide pedagogical instruction for working with diverse populations. We bolster this line of inquiry by sharing activities…

  5. Building Leadership Skills in Middle School Girls through Interscholastic Athletics. ERIC Digest. (United States)

    Hart, Lawrence; Gary, Juneau Mahan; Duhamel, Christie Creney; Homefield, Kimberly

    For the middle school-aged female athlete, self-esteem, empowerment, and self-confidence are often bolstered through participation in interscholastic competitive sports. These traits are also traits of leadership. This digest discusses how many contributing factors and people mold the student athlete into a leader but the process must be…

  6. Apples and Oranges Mean a New Fruit Crop: New Business Plan Competition Model Integrates Economic and Community Development (United States)

    Feldman, Jacqueline; Oden, Lisa Derby


    Mount Wachusett Community College Entrepreneurial Resource Center Business Plan Competition brings together stakeholders across all economic sectors to bolster the regional economy. It also highlights entrepreneurs as a viable career choice. The competition disintegrates existing silos, provides education to all entrants, and gives business…

  7. Women's Educational Opportunities: Factors that Influence Their Graduate School Aspirations (United States)

    Davis, Sharrika D.; Amelink, Catherine; Hirt, Joan B.; Miyazaki, Yasuo


    Education is one key to economic prosperity. However, in a society bolstered by patriarchal systems, economic and educational inequalities exist among the genders. The purpose of this study was to determine whether certain collegiate experiences predict undergraduate women's expectation to enroll in graduate study and to determine if the…

  8. Investigation of Canine-Mediated Human Rabies Death, Haiti, 2015. (United States)

    Tran, Cuc H; Etheart, Melissa D; Andrecy, Lesly L; Augustin, Pierre Dilius; Kligerman, Maxwell; Crowdis, Kelly; Adrien, Paul; Dismer, Amber; Blanton, Jesse D; Millien, Max; Wallace, Ryan M


    In Haiti, an investigation occurred after the death of a 4-year-old girl with suspected rabies. With tips provided by community members, the investigation led to the identification of 2 probable rabies-related deaths and 16 persons bitten by rabid dogs, 75% of which chose postexposure prophylaxis. Community engagement can bolster rabies control.

  9. Investigation of Canine-Mediated Human Rabies Death, Haiti, 2015


    Tran, Cuc H.; Etheart, Melissa D.; Andrecy, Lesly L.; Augustin, Pierre Dilius; Kligerman, Maxwell; Crowdis, Kelly; Adrien, Paul; Dismer, Amber; Blanton, Jesse D.; Millien, Max; Wallace, Ryan M.


    In Haiti, an investigation occurred after the death of a 4-year-old girl with suspected rabies. With tips provided by community members, the investigation led to the identification of 2 probable rabies-related deaths and 16 persons bitten by rabid dogs, 75% of which chose postexposure prophylaxis. Community engagement can bolster rabies control.

  10. 78 FR 26701 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and... (United States)


    ... contains regulatory documents #0;having general applicability and legal effect, most of which are keyed #0...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0... (System) banks, improve the quality of assets in their liquidity reserves, and bolster the ability of...

  11. 78 FR 37101 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and... (United States)


    ... contains regulatory documents #0;having general applicability and legal effect, most of which are keyed #0...;Prices of new books are listed in the first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0...) banks, improve the quality of assets in their liquidity reserves, and bolster the ability of System...

  12. 49 CFR Appendix B to Part 215 - Schedule of Civil Penalties 1 (United States)


    ... outer springs 5,000 7,500 (e) Truck bolster-center plate interference 5,000 7,500 (f) Brake beam shelf... couplers: (a) Shank bent out of alignment 1,000 2,000 (b) Crack in highly stressed junction area. 2,500 5...

  13. Cross-National Impacts of Public-Private Partnerships on Equitable Student Achievement: A Quasi-Experimental Assessment Using PISA 2009 (United States)

    Baum, Donald Rey


    Public-private partnerships are being increasingly supported and advocated for, ideologically and financially, as an approach to educational reform in many countries across the world. Proponents suggest that non-state involvement in the education sector has the potential to bolster international Education for All efforts, improve school…

  14. The Family, Flexible Work and Social Cohesion at Risk. (United States)

    Carnoy, Martin


    Because of women's increased participation in the labor market, there is an increasing pressure on families. Women are expected to provide stability, focus on child development, and bolster colleagues against unemployment and retraining, whereas society is expected to provide child care facilities and flexible education. (JOW)

  15. The Use of the Internet for Alternative Views on Health (United States)

    Bourgoin, Angel


    Today, the majority of American adults uses the internet and looks for health information online. Of interest in this dissertation are people who do not subscribe to mainstream views of health, and may use the internet to discover, bolster, or share their alternative views. Although the Centers for Disease Control and Prevention (CDC) have named…

  16. Establishing the Human Firewall: Reducing an Individual’s Vulnerability to Social Engineering Attacks (United States)


    1988) Bolstering attitudes by autobiographical recall: Attitude persistence and selective memory . Personality and Social Psychology Bulletin, 14...ESTABLISHING THE HUMAN FIREWALL: REDUCING AN INDIVIDUAL’S VULNERABILITY TO SOCIAL ENGINEERING ATTACKS...AFIT/GIR/ENG/08-04 ESTABLISHING THE HUMAN FIREWALL: REDUCING AN INDIVIDUAL’S VULNERABILITY TO SOCIAL ENGINEERING THESIS Presented to the

  17. A Delve into the Deployment of eCommerce and Higher Educational Learning (United States)

    Djoleto, Wilhelmina


    Higher Educational Institutions (HEIs) and organisations have made significant investments in eCommerce/eBusiness in efforts to keep up with heightened technology penetration in organisational and institutional fabrics. These efforts have been incorporated in their strategic mission partly, to bolster their reputation. HEIs reputation depends much…

  18. Fun Club: A Physical Activity Program for Elementary Schools (United States)

    Nye, Susan B.


    Elementary schools have continued to reduce physical education instruction and recess time to bolster classroom instructional time. Many school personnel seem to believe that an increase in time for physical activity or physical education instruction would be counterproductive to students' academic performance. However, due to the rise in…

  19. Pushing the Entrepreneurial Prodigy: Canadian Aboriginal Entrepreneurship Education Initiatives (United States)

    Pinto, Laura Elizabeth; Blue, Levon Ellen


    Globally, neoliberal education policy touts youth entrepreneurship education as a solution for staggering youth unemployment, a means to bolster economically depressed regions, and solution to the ill-defined changing marketplace. Many jurisdictions have emphasized a need for K-12 entrepreneurial education for the general population, and targeted…

  20. Leading to High Performance: A Case Study of the Role of the Balanced Scorecard in Improving Urban Secondary Schools (United States)

    Brown, Pamela C.


    The onset of the standards-based movement in education in the early 1980's, bolstered by the passing of the No Child Left Behind Act (NCLBA) of 2002, led many school districts to shift from a culture of regulatory, process-oriented compliance to one that is more results-oriented, primarily based on state-adopted summative assessment targets in…

  1. 78 FR 35103 - Extension of Border Zone in the State of New Mexico (United States)


    ... border zone was expanded in Arizona in 1999, retail sales in the area increased and the region... view that the 25-mile border zone is antiquated and places the region at a competitive disadvantage... local economy by increasing sales, creating or saving jobs, and bolstering tax revenues. One commenter...

  2. Offering Educational Opportunities to Expelled Students in Wisconsin. Bulletin No. 02030. (United States)

    Fernan, Steve; Parman, Mary Jo; White, Doug; Wiltrout, Dan

    The U.S. Congress bolstered the increase in expulsions by passing into law the federal Gun Free School Act of 1994. All states receiving federal funds were to pass laws requiring schools to expel students who brought firearms to school or to school activities. There is evidence that schools are safer, but expulsion rates continue to climb. With…

  3. 75 FR 29395 - National Maritime Day, 2010 (United States)


    ... America's leadership in the global marketplace, and to our security. Civilian mariners and their ships... continues today. Merchant mariners support military operations in Iraq and Afghanistan, as well as.... They help strengthen our Nation's economy; bolster job-creating businesses; and, along with the...

  4. Case Study: Fuel Cells Provide Combined Heat and Power at Verizon's Garden City Central Office

    Energy Technology Data Exchange (ETDEWEB)



    This case study describes how Verizon's Central Office in Garden City, NY, installed a 1.4-MW phosphoric acid fuel cell system as an alternative solution to bolster electric reliability, optimize the company's energy use, and reduce costs in an environmentally responsible manner.

  5. Data Journalism Grows Up


    Hewett, J.


    Data journalism has evolved partly out of computer-assisted reporting (CAR) in the USA – bolstered by freedom of information (FoI), open data and journalism education. Jonathan Hewett traces the development and teaching of data journalism in the UK.

  6. 76 FR 68623 - National Native American Heritage Month, 2011 (United States)


    ... Indians and Alaska Natives to build a better future together. To strengthen our economy and win the future... communities for too long. We are working to bolster economic development, expand access to affordable health... of tribes and deliver long-awaited trust reform to Indian Country. To bring jobs and sustainable...

  7. Rhetoric and Gender in Jane Austen's "Persuasion." (United States)

    Walzer, Arthur E.


    Argues for a reading of Jane Austen's "Persuasion" that undermines Joseph Duffy's reading of the novel as a commentary on shifting social class structures, and which bolsters Nancy Armstrong's reading as a commentary on female voice and the values of the domestic household. Interprets the novel in the light of 18th-century rhetorical…

  8. Network Centric Operations (NCO) Case Study. The British Approach to Low-Intensity Operations: Part 2 (United States)


    Peace In Ireland. March The IRA plants bombs at Tottenham, Wandsworth Common and Liverpool Street rail stations in London. A 1,000lbs bomb...of tasks to reassure the civilian population and bolster UNAMSIL and the government of Sierra Leone. These tasks included arranging football matches

  9. 78 FR 22789 - Methyl Jasmonate; Exemption From the Requirement of a Tolerance (United States)


    ...) inducer on a variety of agricultural crops. It is applied pre-harvest as a seed treatment and an in-furrow soil treatment. Methyl jasmonate is a naturally occurring biochemical hormone found in most plants. It... variety of stresses. Methyl jasmonate, in particular, is known to bolster plant defenses against extreme...

  10. “Carried Us Away in Captivity:” The Oscar, the Tsotsi, and the ...

    African Journals Online (AJOL)

    African forgiveness and reconciliation (or perhaps because it simply was not as good), Jerusalema not only did not bring Oscar's golden statue back to. South Africa, but indeed did not make the cut of five foreign language finalists at the 2009 Academy Award ceremonies. Ironically, that Hollywood snub may have bolstered ...

  11. Gaming the System: Culture, Process, and Perspectives Supporting a Game and App Design Curriculum (United States)

    Herro, Danielle


    Games and digital media experiences permeate the lives of youth. Researchers have argued the participatory attributes and cognitive benefits of gaming and media production for more than a decade, relying on socio-cultural theory to bolster their claims. Only recently have large-scale efforts ensued towards moving game play and design into formal…

  12. The Impact of Motivational Interviewing on Client Experiences of Cognitive Behavioral Therapy for Generalized Anxiety Disorder (United States)

    Kertes, Angela; Westra, Henny A.; Angus, Lynne; Marcus, Madalyn


    Motivational Interviewing (MI) has recently been applied to the treatment of anxiety disorders in an effort to bolster engagement with and response rates to cognitive behavioral therapy (CBT). In a recent randomized control trial, the addition of MI as a pretreatment compared to no pretreatment was found to significantly improve response to CBT…

  13. An Inevitable Moment: US Brain Drain (United States)

    Coppola, Brian P.


    In this article, Brian Coppola begins by discussing the 2007 National Academies of Sciences (NAS) publication, "Rising Above the Gathering Storm" which called for for reprioritizing investments because "the world is changing rapidly, and our advantages are no longer unique. Without a renewed effort to bolster the foundations of our…

  14. Energy Perspective: Is Hydroelectricity Green? (United States)

    Childress, Vincent W.


    The current worldwide concern over energy is primarily related to imported oil, oil drilling and refining capacity, and transportation capacity. However, this concern has bolstered interest in a broader range of "green" energy technologies. In this article, the author discusses the use of hydroelectricity as an alternative energy source…

  15. "When" Students Miss School: The Role of Timing of Absenteeism on Students' Test Performance (United States)

    Gottfried, Michael A.; Kirksey, J. Jacob


    Policy and practice have charged forward with emphasizing the necessity to reduce school absenteeism in the fall (i.e., Attendance Awareness Month). However, no empirical basis served to bolster these efforts. This study examined whether fall versus spring absenteeism was linked to spring state exam scores for a sample of elementary students over…

  16. Mediation: One Alternative to Traditional Judicial Proceedings. (United States)

    Dunn, Merrily S.


    Presents a model of conflict resolution as an alternative, or in addition, to traditional disciplinary systems. Method relies on mediation and employs a "win/win" philosophy which allows and encourages students to peacefully resolve their own disputes. Believes that the program bolsters self-esteem and helps students resolve differences.…

  17. Investigating the reasons behind the increase in medical negligence ...

    African Journals Online (AJOL)

    The contribution further focuses on patient-centred legislation and pronouncements by courts that bolster patient autonomy and place patients in an ever stronger position to enforce their rights. Relevant provisions of the Constitution, the National Health Act, the Consumer Protection Act and the Children's Act are singled out ...

  18. Exploring the Experiences of School Counselor-Administrator Teams in Their Work with LGBT Students: A Phenomenological Study (United States)

    Beck, Matthew Jon


    Research suggests the collaborative role school counselors can have with administrators to bolster school reform and facilitate a safe and positive learning environment for all K-12 students (College Board, 2009a, 2009b) is vital. Unfortunately, research that explores the roles and efforts of school counselors and administrators in their…

  19. Tracing tribe: Hugh Tracey and the cultural politics of retribalisation ...

    African Journals Online (AJOL)

    The enclosed essay challenges the impulse of Hugh Tracey apologists who argue that the South African musicologist's work in cultural preservation absolves his resistance to musical syncretism, which in many ways bolstered the retribalisation efforts of apartheid South Africa. By viewing musical hybridity as culturally ...

  20. Reframing Internationalization (United States)

    Garson, Kyra


    Canadian higher education has long been involved in international education, partnerships, and research and development projects; however, recent framing of international education as an industry generating revenues to prop up underfunded institutions is troubling. This approach is endorsed by provincial government strategies and bolstered by the…

  1. Engineering in Elementary STEM Education: Curriculum Design, Instruction, Learning, and Assessment (United States)

    Cunningham, Christine M.


    Bolstered by new standards and new initiatives to promote STEM education, engineering is making its way into the school curriculum. This comprehensive introduction will help elementary educators integrate engineering into their classroom, school, or district in age-appropriate, inclusive, and engaging ways. Building on the work of a Museum of…

  2. 76 FR 31680 - Open Meeting of the President's Council on Jobs and Competitiveness (PCJC) (United States)


    ... initiatives and policies to strengthen the economy, promote and accelerate job growth and bolster America's... the government and business can work together to foster growth and create jobs. The PCJC will also... change, including any business or personal information provided such as names, addresses, e-mail...

  3. Identifying Best Practices in Training Transfer: A Qualitative Study of Training Professionals (United States)

    Burke, Lisa A.; Hutchins, Holly


    Qualitative data were gathered from trainers regarding best practices for supporting training transfer. Using content analysis, findings suggest interventions for bolstering transfer are best carried out in the work context and design/delivery phase, take place after training or during, and involve trainers and supervisors. However, trainers…

  4. Adaptive plasticity during stress and depression and the role of ...

    African Journals Online (AJOL)

    Stress in various guises may alter synaptic connectivity in the brain by bolstering glutamatergic excitotoxic mechanisms. Understanding these mechanisms may assist in developing more effective treatment strategies. This paper will review pre-clinical and clinical evidence supporting a role for the glutamatenitric oxide ...

  5. The Information Society: Image versus Reality in National Computer Plans. (United States)

    George, Joey F.; And Others


    Examines what the term "information society" really means and investigates how it is related to national computer plans (NCPs). Analysis of several NCPs indicates that nations are more concerned with a general need to bolster and improve their national economies than in encouraging social transformation. (JKP)

  6. The Tonya Harding Controversy: An Analysis of Image Restoration Strategies. (United States)

    Benoit, William L.; Hanczor, Robert S.


    Analyzes Tonya Harding's defense of her image in "Eye to Eye with Connie Chung," applying the theory of image restoration discourse. Finds that the principal strategies employed in her behalf were bolstering, denial, and attacking her accuser, but that these strategies were not developed very effectively in this instance. (SR)

  7. Responding to organised environmental crimes: Collaborative ...

    African Journals Online (AJOL)

    The aim of this article is to discuss the ways in which collaboration and a coordinated approach to dealing with criminal groups involved in environmental crime can be established and bolstered. The article begins by examining the challenges associated with organised criminal networks and transnational crimes for ...

  8. Where's the Vision? The Concept of Utopia in Contemporary Educational Theory (United States)

    Webb, Darren


    This paper explores the way in which the concept of utopia is employed within contemporary educational theory. Confronted with the relentless marketisation and managerialisation of education, there is a growing willingness to embrace utopianism as a means of bolstering hope, opening up new possibilities and catalysing change. At the same time,…

  9. A World of Competitors: Assessing the US High-Tech Advantage and the Process of Globalisation (United States)

    Douglass, John Aubrey


    Research universities throughout the world are part of a larger effort by countries to bolster science and technological innovation and compete economically. The United States remains highly competitive as a source of high-tech innovation because of a number of market positions, many the results of long-term investments in institutions (such as…

  10. Anglo-South African relations and the Erebus Scheme, 1936-1939 ...

    African Journals Online (AJOL)

    South African Defence Minister, Oswald Pirow, endeavoured to obtain 15-inch guns from Britain to bolster Cape Town's defences against sea-raiders. Despite her strategic interest in safeguarding the Cape sea route, Britain's own efforts at rearmament, however, made her unwilling to part with guns of that calibre. Instead, in ...

  11. Conceptualizing Media Stimuli in Experimental Research: Psychological versus Attribute-Based Definitions (United States)

    Tao, Chen-Chao; Bucy, Erik P.


    This paper argues for a clearer conceptualization of media stimuli in experimental research and identifies 3 issues impeding our understanding of message processing: (a) assumptions bolstered by manipulation checks about homogeneity of response to media stimuli, (b) conflation of 2 different classes of variables--media attributes and psychological…

  12. Do Smallholder, Mixed Crop-Livestock Livelihoods Encourage Sustainable Agricultural Practices? A Meta-Analysis

    NARCIS (Netherlands)

    Rudel, Thomas K.; Kwon, Oh-Jung; Paul, B.K.


    As calls for bolstering ecosystem services from croplands have grown more insistent during the past two decades, the search for ways to foster these agriculture-sustaining services has become more urgent. In this context we examine by means of a meta-analysis the argument, proposed by Robert McC.

  13. Using symbolic meaning as a means to design for happiness : The development of a card set for designers

    NARCIS (Netherlands)

    Marques Ribeiro daSilva Casais, M.; Mugge, R.; Desmet, P.M.A.; Lloyd, Peter; Bohemia, Erik


    Using design to improve the lives of people towards a positive flourishing state is the main premise of Positive Design. Our contribution to this growing field focuses on making use of the symbolic meaning that design can have to bolster
    human happiness. This paper presents the development of a

  14. Universities, the US High Tech Advantage, and the Process of Globalization. Research & Occasional Paper Series: CSHE.8.2008 (United States)

    Douglass, John Aubrey


    Research universities throughout the world are part of a larger effort by nation-states to bolster science and technological innovation and compete economically. The US remains highly competitive as a source of High Tech (HT) innovation because of a number of market positions, many the result of long term investments in institutions such as…

  15. Why the NEA and AFT Sought To Merge--and Failed. (United States)

    Fusarelli, Lance D.; Cooper, Bruce S.


    Four key reasons underlie the push for teacher union solidarity in 1998: desire to fulfill Al Shanker's dream of a unified mission, to end union competition, to bolster Democratic Party weaknesses, and to stop privatization. The NEA/AFT merger failed because of conflicting organizational cultures and teachers' gradualist, localist, and…

  16. Sanctuary … and Other Notes from the "NEJHE" Beat … (United States)

    Harney, John O.


    How will higher education fare under a President Donald Trump? According to this author, the campaign's misogyny shouldn't sit well with a student body that is now majority female, its disavowal of climate changes won't impress research universities, and the xenophobia won't help economies and cultures bolstered by foreign enrollment. The number…

  17. Selected Spiritual, Religious, and Family Factors in the Prevention of School Violence (United States)

    Windham, R. Craig; Hooper, Lisa M.; Hudson, Patricia E.


    The mass-casualty school shooting incidents in recent years have heightened concern about the safety of U.S. schools and prompted responses that, in many cases, have centered mainly on bolstering security on school campuses. Some researchers have concluded, however, that the most effective prevention efforts are those that are more comprehensive…

  18. College Enhancement Strategies and Socioeconomic Inequality (United States)

    Wolniak, Gregory C.; Wells, Ryan S.; Engberg, Mark E.; Manly, Catherine A.


    The study provides new information on the relationships between students' socioeconomic backgrounds, utilization of college enhancement strategies, and subsequent 4-year college enrollment. Enhancement strategies represent student behaviors used to bolster the competitiveness of a college application, such as Advanced Placement exams and a variety…

  19. Mood-Congruent Memory and Natural Mood: New Evidence. (United States)

    Mayer, John D.; And Others


    Presents new evidence that everyday mood does bring about a hypothesized effect on memory, termed mood-congruent memory (MCM). Results of three studies provided evidence for MCM among normal individuals (n=614). Findings support prior studies and bolster notions that mood and memory constantly covary in everyday experience. (RJM)

  20. Vitality and Ethnolinguistic Attitudes of Acadians, Franco-Ontarians and Francophone Quebecers: Two or Three Solitudes in Canada's Bilingual Belt? (United States)

    Sioufi, Rana; Bourhis, Richard Y.; Allard, Réal


    Do French-Canadian (FC) minorities in New Brunswick and Ontario remain as committed as majority Francophone Quebecers in developing their vitality within Canada's bilingual belt? FCs constitute host communities for interprovincial migrants of FC and English-Canadian (EC) background who can bolster or weaken the vitality of FCs. How FCs and ECs…

  1. Capitalizing on Concern: The Making of Troubled Children and Troubling Youth in Late Capitalism. Introduction. (United States)

    Finn, Janet L.; Nybell, Lynn


    Introduces special issue examining how constructions of pathology during childhood and adolescence play out along lines of gender, race, class, age, and citizenship in ways that locate problems in the individual, bolster extant constructions of difference and inequality, and make possible connections between constructions of pathology and…

  2. Rural Elementary Teachers and Place-Based Connections to Text during Reading Instruction (United States)

    Waller, Rachael; Barrentine, Shelby J.


    Schooling can play a role in bolstering a sense of community, but research suggests that curriculum may serve to isolate teachers and students from their rural surroundings. In this qualitative case study, we asked if the literacy curriculum and instruction supported readers to make connections to their rural setting. We analyzed curriculum…

  3. School System (Re)design: Developing Educational Infrastructures to Support School Leadership and Teaching Practice (United States)

    Hopkins, Megan; Woulfin, Sarah L.


    A central challenge for local education agencies (i.e., school districts in the United States) undergoing reform is to design systems that facilitate instructional improvement. At the core of these systems are educational infrastructures that bolster capacity building efforts and support teaching and leadership practices. Our goal for this special…

  4. Things will get better: the anxiety-buffering qualities of progressive hope

    NARCIS (Netherlands)

    Rutjens, B.T.; van der Pligt, J.; van Harreveld, F.


    Terror management theory argues that people can cope with the psychological threat of their own death by bolstering faith in their cultural worldviews. Based on the notion that—since the Age of Enlightenment—belief or faith in progress has become one of the defining qualities of modern Western

  5. 78 FR 73923 - Privacy Act of 1974, as Amended; System of Records (United States)


    ... and bolster taxpayer confidence in the Federal Government's management of taxpayer dollars. Under...), and Preparer Taxpayer Identification Number (PTIN)); (c) Date of birth; (d) Home and work address; (e... accuracy of system records; (f) Disclosure to financial institutions and their servicers in order (1) to...

  6. Darwin's invisible hand: Market competition, evolution and the firm

    NARCIS (Netherlands)

    Johnson, D. D. P.; Price, M. E.; van Vugt, M.


    Competition among firms has been suggested to reflect the ruthless logic of Darwinian selection: a free market is a struggle for survival, in which successful firms survive and unsuccessful ones die. This view appears to bolster three pillars of neoclassical economics: (1) that economic actors are

  7. Building A New South Africa: Volume 3: Science and Technology ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Unfortunately, these structures and people have been guided by a policy based on benefiting a minority and supporting the security needs of a regime whose primary objective was to maintain apartheid. The use of S&T to bolster apartheid resulted in an international cultural and scientific boycott of South Africa. This had the ...

  8. Comparison of Service Effectiveness for Youth with Depressed Versus Nondepressed Caregivers (United States)

    McCarthy, Michael; Schellinger, Jeffrey; Smith, Rachel R.; Behimer, Gretchen; Hargraves, Daniel; Scherra, Karen


    Purpose: (1) To compare demographic, mental health, service usage, and emotional and behavioral characteristics and strengths of youth receiving care from depressed versus nondepressed caregivers and (2) to determine whether a community-based program for reducing problematic behaviors and bolstering strengths is equally effective for youth with…

  9. Partnership for the Advancement of Information Literacy in a Nursing Program (United States)

    Beck, Sheila; Blake-Campbell, Barbara; McKay, Devin


    Nursing educators know that healthcare stakeholders expect nursing graduates to be able to manage information. Consequently, many nursing education programs are exploring ways of integrating information literacy across the curriculum not only to bolster evidence-based practice, but also to enhance professional development and encourage lifelong…

  10. IDRC in Malaysia

    International Development Research Centre (IDRC) Digital Library (Canada)

    As Malaysia became an upper middle-income economy and the government made funding for research a priority in the 1990s, IDRC scaled back its support. Recent IDRC funding has bolstered Malaysian efforts to under stand how the knowledge economy can benefit the poor and has promoted the use of new technologies.

  11. Biomedical Research and the Animal Rights Movement: A Contrast in Values. (United States)

    Morrison, Adrian R.


    This article explains how animals are used in research in an effort to counteract animal rights literature. Reveals how medical professionals and others trained in scholarship have misquoted the scientific literature to bolster their claims against the utility of animal research. (PR)

  12. Resilience Training for Healthcare Staff (RTHS) Implementation Evaluation Phase 1 (United States)


    05-01-2017 2. REPORT TYPE Technical Report 3. DATES COVERED (From - To) JUN 2016 - JAN 2017 4. TITLE AND SUBTITLE Resilience Training for...DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release: distribution unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT The Master Resilience ...Training (MRT) Medical Program includes a 2-hour Resilience Training for Healthcare Staff (RTHS) aimed to bolster resilience by preventing

  13. Getting Students Excited about Learning: Incorporating Digital Tools to Support the Writing Process (United States)

    Saulsburry, Rachel; Kilpatrick, Jennifer Renée; Wolbers, Kimberly A.; Dostal, Hannah


    Technology--in the form of digital tools incorporated into writing instruction--can help teachers motivate and engage young children, and it may be especially critical for students who do everything they can to avoid writing. Technology may bolster student involvement, foster the engagement of reluctant or struggling writers, and support writing…

  14. Looking Past the Spin: Teach for America (United States)

    Miner, Barbara


    Teach for America (TFA) is perceived as a major player in the education wars over the future of public schools, and a key ally of those who disparage teacher unions and schools of education, and who are enamored of entrepreneurial reforms that bolster the privatization of a once-sacred public responsibility. But what exactly is TFA's role in these…

  15. From Swimming Pool to Collaborative Learning Studio: Pedagogy, Space, and Technology in a Large Active Learning Classroom (United States)

    Lee, Dabae; Morrone, Anastasia S.; Siering, Greg


    To promote student learning and bolster student success, higher education institutions are increasingly creating large active learning classrooms to replace traditional lecture halls. Although there have been many efforts to examine the effects of those classrooms on learning outcomes, there is paucity of research that can inform the design and…

  16. Biochar: What is the future for industrial production and world usage? (United States)

    Biochar has gained world attention as a soil amendment to increase carbon sequestration, improve fertility levels and bolster soil water retention. Unfortunately, the amount of biochar needed for field application rates to achieve these results can be in the tons per hectare range. There is concer...

  17. 77 FR 66523 - National Entrepreneurship Month, 2012 (United States)


    ... directed Federal agencies to streamline processes for establishing public-private research partnerships...; and save taxpayers money. In addition, thousands of American entrepreneurs and inventors are helping... and Job Creation Act I signed in February, we have bolstered Self-Employment Assistance programs that...

  18. International Students' Emotional Security and Dignity in an Australian Context: An Aspect of Psychological Well-Being (United States)

    Tananuraksakul, Noparat; Hall, David


    This article explores non-native English-speaking students' emotional security and dignity responses to their English language proficiency in an Australian context. Confidence is a source of emotional security bolstering dignity. Without it, students lack emotional security, diminishing their dignity when communicating with culturally different…

  19. 78 FR 59342 - 36(b)(1) Arms Sales Notification (United States)


    ... is published to fulfill the requirements of section 155 of Public Law 104-164 dated July 21, 1996... strengthen its homeland defense, as well as support counter-terrorism operations. These systems will bolster Tunisia's ability to continue supporting its air and ground forces in counter-terrorism and border...

  20. Using the World Wide Web To Teach Francophone Culture. (United States)

    Beyer, Deborah Berg; Van Ells, Paula Hartwig


    Examined use of the World Wide Web to teach Francophone culture. Suggests that bolstering reading comprehension in the foreign language and increased proficiency in navigating the Web are potential secondary benefits gained from the cultural Web-based activities proposed in the study.(Author/VWL)

  1. From Shards to Stained Glass: Crowdsourcing an E-Book (United States)

    Fontichiaro, Kristin


    In this article, the author discusses crowdsourcing an e-book--gathering wide, diverse opinions from the school library community (including academics, practitioners, vendors, and others), and gathering those results in a free e-book. As e-book publishers, school librarians could be active agents, bolstering community energy, creating a forum for…

  2. Explaining participation of private forest owners in economic incentives. Case studies in Europe

    DEFF Research Database (Denmark)

    Górriz, E.; Mäntymaa, E.; Petucco, C.


    objectives or the land management measures they promote. It demonstrates that the design of mechanisms bolstering synergies between current landowners’ practices and expectations to those demanded by externals have more likelihood of success than those implying drastic management changes. On the other hand...

  3. 76 FR 32857 - Great Outdoors Month, 2011 (United States)


    ..., America's great outdoors have ignited our imaginations, bolstered our economy, and fueled our national... generation of urban parks and community green spaces; and create a new Conservation Service Corps so that... improve our quality of life and our health, rejuvenate local and regional economies, spur job creation...

  4. Linking resilience theory and diffusion of innovations theory to understand the potential for perennials in the U.S. Corn Belt (United States)

    Ryan C. Atwell; Lisa A. Schulte; Lynne M. Westphal


    In the last 200 yr, more than 80% of the land in the U.S. Corn Belt agro-ecosystem has been converted from natural perennial vegetation to intensive agricultural production of row crops. Despite research showing how re-integration of perennial vegetation, e.g., cover crops, pasture, riparian buffers, and restored wetlands, at strategic landscape positions can bolster...

  5. Escalation and Intrawar Deterrence During Limited Wars in the Middle East (United States)


    the stereotype of massive Israeli military superiority. As a hedge, to ensure that Israel’s powerful air force was bolstered with ongoing support...leadership promising massive nuclear retaliation in ways that were impossible to misinterpret.169 Publicly Yitzhak Rabin, a Labour Party leader, who had

  6. Minimum Wages and Skill Acquisition: Another Look at Schooling Effects. (United States)

    Neumark, David; Wascher, William


    Examines the effects of minimum wage on schooling, seeking to reconcile some of the contradictory results in recent research using Current Population Survey data from the late 1970s through the 1980s. Findings point to negative effects of minimum wages on school enrollment, bolstering the findings of negative effects of minimum wages on enrollment…

  7. Practice Stories in Natural Resource Management Continuing Professional Education: Springboards for Learning (United States)

    Stummann, Cathy Brown


    The use of stories from professional experience in continuing professional education has been on the rise in many fields, often aimed at bolstering capacity through sharing professional knowledge and/or supporting reflective practice. Practice stories are also suggested to be beneficial in supporting professional learning of new concepts. These…

  8. Turning up the contrast: self-enhancement motives prompt egocentric contrast effects in social judgments. (United States)

    Beauregard, K S; Dunning, D


    Contrast effects occur when people judge the behavior and attitudes of others relative to their own. We tested a motivational account suggesting that these effects arise because people tailor their judgments of others to affirm their own self-worth. Consistent with that interpretation, participants displayed more egocentric contrast in their judgments of another person's intelligence (i.e., their evaluation of his score on the Scholastic Aptitude Test was more negatively related to their own score) after their self-esteem was threatened than after it was bolstered (Studies 1 and 2). High-self-esteem individuals displayed more judgmental contrast overall than did their low-esteem counterparts (Study 2). Strongly pro-choice participants whose esteem was threatened also displayed more contrast in their judgments of another person's attitude on abortion, relative to esteem-bolstered participants (Study 3). Discussion centers on the implications of these findings for theory on social comparison, self-affirmation, and social judgment.

  9. Fatigue life analysis of die forged railway axle manufactured from C30 steel

    Directory of Open Access Journals (Sweden)

    Libor Trško


    Full Text Available With respect to the manufacturing process, different parts of one structural component can have different fatigue properties. In this study, the fatigue life of a railway axle manufactured from C30 steel by die forging is evaluated in the part of the axle bolster and axle body. According to the fatigue test results obtained at high frequency tension - compression fatigue tests (f ≈ 20 kHz, R = -1, T = 20 ± 5 °C, due to the higher level of work hardening of the axle bolster, the fatigue strength of material in this part is significantly higher than in the axle body. Different fatigue strength of these parts were observed despite the fact, that results of static tensile tests did not proved any important differences in the ultimate tensile strength, yield point and elongation. 

  10. The Art of Appeal in Electronic Commerce

    DEFF Research Database (Denmark)

    Liu, Albert Fei; Xiao, Bo Sophia; Lim, Eric T. K.


    Purpose: The purpose of this paper is to advance product appeal and website appeal as focal psychological mechanisms that can be invoked by business-to-consumer e-commerce sites to mitigate problems of information asymmetry via signaling to bolster consumers’ purchase intention under the influence...... of trust. Design/methodology/approach: Survey approach was employed to validate the research model. Findings: Website appeal partially mediates the positive effect of product appeal on consumers’ purchase intention. Trust in e-commerce sites not only increases purchase intention directly, but it also...... diagnosticity and justifiability are established as positive antecedents of product appeal. Research limitations/implications: This study not only delineates product and website appeal as complementary drivers of consumer purchase on e-commerce sites, but it also derives five signals that aid in bolstering both...

  11. Visual Elements in Flight Simulation (United States)


    greater than the earliest simu- lators. Motion capability has been restored becaise a great deal of evidence bolstered by virtually unanimous pilot...March, 1970, Pip ,r No. 70-347. 10. Ganzler, Bruce C. Virtual image display for flight simulation. NASA Technical Memorandum, NASA TM X-2327, July...studies can be conducted. e. John Dusterberry, Asistant Chief, Simulation Sciences Division, presented remarks on "State-of-the-Art in Visual

  12. A Photo Essay of a Failed Reform


    Zweig, David


    In mid-1975, Deng Xiaoping, with Mao’s blessing, initiated reforms that targeted the negative consequences of the Cultural Revolution. To bolster Deng’s effort, Mao endowed him with penultimate authority over the Party, government, and military. However, in late October, Mao turned on Deng, and within five months, Mao and the radicals toppled Deng from power. As a foreign student at Peking University, David Zweig observed and photographed four key points in this historic struggle: (1) the ini...

  13. The Duterte Administration’s Foreign Policy: Unravelling the Aquino Administration’s Balancing Agenda on an Emergent China


    Renato Cruz De Castro


    From 2010 to 2016, then-President Benigno Aquino balanced China's expansive maritime claim in the South China Sea. President Aquino challenged China by shifting the AFP's focus from domestic security to territorial defence, bolstering closer Philippine-US security relations, acquiring American military equipment, seeking from Washington an explicit security guarantee under the 1951 Mutual Defence Treaty (MDT), and promoting a strategic partnership with Japan. However, the Duterte administrati...

  14. Clicks and bricks : assessing the viability of a food cooperative in Central Pennsylvania


    Carlin, Neal Christian


    As interest in local foods reaches previously unfathomable heights in the United States, there is a growing diversity of business models to bolster local food economies and increase access to a wider range of high quality local products. The cooperative model, in which the business or organization is owned and operated by its users for their benefit, has existed in the food and agricultural sectors for well over a century, but is seeing a resurgence in popularity in recent years. This case st...

  15. Entrepreneurship as a Source of Economic, Political, and Social Improvement in Sub-Saharan Africa (United States)


    thank my wife , Margarita, for her unwavering love and support during my 15-month study. Despite the many long hours at the library, our time in...government.84 The discovery of little transition from necessity entrepreneurship to opportunity entrepreneurship supports this argument.85 Opportunity...and will bolster more entrepreneurship support .104 Lastly, a high level of technological readiness, especially in efficiency-driven countries, could

  16. Photovoltaic Barometer - EurObserv'ER - April 2013

    International Nuclear Information System (INIS)


    After the euphoria of 2011, the European Union's photovoltaic market slowed right down in 2012. EurObserv'ER puts newly-connected capacity in 2012 at 16.5 GWp compared to 22 GWp in 2011, which is a 25% slide. At global level the market generally held up, with just over 30 GWp installed, bolstered by the build-up of the America and Asian markets

  17. Defending the jurisdiction of the clinical ethicist. (United States)

    Evans, John H


    In this essay I suggest that the bioethics profession's jurisdiction over healthcare ethics consultation is in need of reinforcement. I argue that as the profession becomes more successful, competitors will challenge the profession to justify its ethical claims and ask whose ethics the profession represents. This challenge will come more quickly as the profession tries to influence the ethics of healthcare organizations. I propose a method of bolstering jurisdiction that will make the profession less vulnerable to challenge in the future.

  18. Non-Tactical Vehicle Replacement for the Department of the Navy’s Medium- and Heavy-Duty Vehicle Fleet (United States)


    incentives have helped bolster the EV and HEV market. Additionally, battery storage technology is helping to bring the costs of owning an electric vehicle ...replace the existing medium- and heavy-duty non-tactical vehicle fleet. These technologies were electric , hybrid- electric , and compressed natural gas...the existing medium- and heavy-duty non-tactical vehicle fleet. These technologies were electric , hybrid- electric , and compressed natural gas. All



    served to bolster public opinion which favored MacArthur and his promise to return to the Phillipines , thereby influencing perseverance and... Phillipines to add leverage to his argument for overall strategy which focused upon a southern approach to Japan through the Phillipines .12     MacArthur’s...key strategic objective of the Phillipines . Within the campaign itself, several successive objectives were established that shaped the combat

  20. CAES Annual Report FY 2011

    Energy Technology Data Exchange (ETDEWEB)

    Kortny Rolston


    The Center for Advanced Energy Studies was created to lead research programs important to the nation, attract students and faculty to the Idaho universities and act as a catalyst for technology-based economic development. CAES is striving to meet those goals by continuing to develop its infrastructure and equipment capabilities, expand its research portfolio and bolster Idaho's energy workforce. This Annual Report details the progress CAES made in FY 2011 toward fulfilling its research, education and economic development missions.

  1. The Effects of U.S. National Security Strategy on Force Structure and the National Industrial Base: 1945-1960 (United States)


    a withdrawal of these troops would lead to a communist takeover of the peninsula from both the Central Intelligence Agency (CIA, formerly the OSS...Korean revolts and bolster South Korean forces as an effective deterrent to a communist takeover there, General MacArthur recommended otherwise. He...Fifth Regimental Combat Team from South Korea to Hawaii .60 On 23 September 1949, Truman announced to the nation the successful development of a

  2. Protecting Our Future--Developing a National School Security Standard (United States)


    system is prevalent in other industries and could be quickly modified to bolster the protection needed for school buildings.2 Some component agencies...manufacturing, defense industrial base, emergency services, energy, financial services, food and agriculture, government facilities, healthcare and...School in Red Lion, Pennsylvania on April 24, 2003. The student attacker shot and killed his principal in the cafeteria prior to committing suicide.178

  3. Extended Nuclear Deterrence for Europe Without Forward-based Weapons (United States)


    financial costs of nuclear burden sharing, bolsters safety and security and further reduces proliferation risks. 22 Bibliography Bildt, Carl and... Sagan , Scott D. and Waltz, Kenneth N. The Spread of Nuclear Weapons: A Debate Renewed. W. W. Norton and Company New York, NY and London...Point. Center for International Relations, Reports and Analyses. Konrad-Adenauer Foundation, Warsaw, 2011, 2. 30 Bildt, Carl and Sikorski, Radek

  4. Logistic Regression for Extremely Rare Events: The Case of School Shootings


    Christian Westphal


    School shootings are often used in public policy debate as a justification for increased regulation, based on qualitative arguments. However, to date, no effort has been made to find valid quantitative evidence for the claims bolstering the regulation recommendations. In defense of this absence of evidence, it is usually argued that the rarity of such events does not allow the employment of quantitative methods. This paper, using a simulation study, shows that, based on the number of shool sh...

  5. Cognitive Prescriptions: A Nursing Approach to Increasing Cognitive Reserve


    Vance, David E.; Eagerton, Greg; Harnish, Brenna; McKie-Bell, Peggy; Fazeli, Pariya L.


    Non-pathological cognitive declines occur with aging, which negatively affects everyday functioning and reduces quality of life. Many elders, aware of such cognitive changes, seek ways to bolster their cognitive functioning. Evidence based on the cognitive aging literature supports a number of factors associated with cognitive functioning. These factors include physical exercise, intellectual exercise, nutrition, sleep hygiene, social interaction, and mood and emotional state. These factors c...

  6. Connecting America’s People with America’s Army: Breaching the Perceptual Divide (United States)


    public – young and old – thinks the younger generation is more racially tolerant than their elders. In their views about interracial dating, for example...firsthand experience or information passed down from generations. They can adopt policies commensurate with societal norms and laws. For example, the... adopt unwavering entry standards, and continue to remove institutional barriers. The Army should bolster quality education and employment benefit

  7. Criminalising violence against women: feminism, penality, and rights in post neoliberal Ecuador


    Tapia Tapia, Silvana Cristina; National Secretary of Higher Education, Science and Technology of Ecuador


    This thesis asks how penality, understood as the whole of the penal complex, with its laws, procedures, and sanctions, has become central to feminist strategies to counteract violence against women (VAW) in Ecuador. A new penal code came into force in 2014, criminalising some forms of domestic VAW, which had thus far been treated as misdemeanours, and introducing the new crime of "femicide". The thesis argues that human rights discourses have played a crucial role in bolstering penality by pr...

  8. Airsea Battle to Joint Concept for Access and Maneuver in the Global Commons: Imperative for a Continuation of a Crucial Warfighting Concept (United States)


    Russia and China are introducing. 3 U.S. White House, National Security Strategy...guidance from the White House allowed an unrestrained military to create a mythical enemy in China to bolster demands for research and development funding...New Offset Strategy: Exploiting U.S. Long-Term Advantages to Restore U.S. You should not pour new wine into old vessels. Heinz

  9. The global accounting experiment


    Nicolas Véron


    In this essay, Nicolas Véron presents accounting standard-setting as a frontier experiment in international governance, where private initiative can succeed in solving a collective problem that nation-states could not tackle effectively. To make the adoption of International Financial Reporting Standards (IFRS) in Europe and other jurisdictions sustainable, the legitimacy of the International Accounting Standards Board has to be bolstered through significant governance changes; and their impl...

  10. 2015 QuickCompass of Sexual Assault Prevention and Response-Related Responders (QSAPR). Overview Report (United States)


    education so SARCs and VAs can maximize the tools they have for supporting male survivors of sexual assault. Familiarity with SAPRO area where ongoing education about the value of the SVC/VLC program may ultimately bolster support options for survivors of sexual assault...Lower Response SARCs Demonstrate awareness of the impact of sexual assault on survivors 85 83 87 81 91 Facilitate education and training 82 81 77

  11. Citizen Science as a Tool for Augmenting Museum Collection Data from Urban Areas


    Dakota M. Spear; Gregory B. Pauly; Gregory B. Pauly; Kristine Kaiser; Kristine Kaiser; Kristine Kaiser


    Museum collections are critical to contemporary biological research, but museum acquisitions have declined in recent decades, hampering researchers' ability to use collections to assess species responses to habitat modification, urbanization, and global climate change. Citizen science may be a key method to bolster museum collections data, particularly from urban regions, where ongoing data collection is critical to our understanding of ecosystem dynamics in a highly modified and variable lan...

  12. Post-Conflict History Education in Finland, South Africa and Bosnia-Herzegovina


    Ahonen, Sirkka


    A post-conflict society tends to get locked in a history war. As the practice of history in its broad sense is a moral craft, representations of guilt and victimhood prevail in social memory. The representations are often bolstered by mythical references, wherefore deconstruction of myths is expected from history education for the purposes of post-conflict reconciliation. This article deals with the post-conflict uses of history in Finland, South Africa and Bosnia-Herzegovina. The three cases...

  13. Exploiting the bad eating habits of Ras-driven cancers. (United States)

    White, Eileen


    Oncogenic Ras promotes glucose fermentation and glutamine use to supply central carbon metabolism, but how and why have only emerged recently. Ras-mediated metabolic reprogramming generates building blocks for growth and promotes antioxidant defense. To fuel metabolic pathways, Ras scavenges extracellular proteins and lipids. To bolster metabolism and mitigate stress, Ras activates cellular self-cannibalization and recycling of proteins and organelles by autophagy. Targeting these distinct features of Ras-driven cancers provides novel approaches to cancer therapy.

  14. Should knowledge of classical dance be essential for medical practitioners?

    Directory of Open Access Journals (Sweden)

    Shovana T Narayan


    Full Text Available The medical field is constantly throwing challenges, leading to considerable stress for its practitioners. Medical practitioners are expected to be professional, have up-to-date knowledge and expertise, and the ability to withstand fatigue. Through it all they are expected to remain motivated, respectful and humane, patient and kind, and confident and sensitive. The author demonstrates how learning dance can stimulate creativity, increase motivation and bolster social intelligence in medical practitioners.

  15. Synthetic studies toward complex Schisandraceae and zoanthamine natural products


    Fischer, Derek A.


    Natural products, or secondary metabolites of plants and animals, have proven invaluable to humanity. We have used them for myriad reasons throughout history, including non- essential purposes such as dyes for textiles and paints. Less trivial uses, such as those related to food and health better demonstrate the importance of natural products. We have made use of toxic natural products to bolster hunting efficiency (e.g. poison tipped darts), and insect pheromones and natural products with an...

  16. The chemistry and biology of zoanthamine alkaloids and Illicium sesquiterpenes


    Trzoss, Lynnie L.


    Natural products, or secondary metabolites, have proven significant to the existence of life. They have been used for countless reasons throughout history, including nonessential purposes such as dyes for textiles and paints. Less trivial uses, such as those related to health better demonstrate the importance of natural products. Toxic natural products had been used to bolster hunting efficiency and insect pheromones. Therapeutic natural products have long been used as dietary supplements and...

  17. Pengaruh Kepemimpinan Dan Lingkungan Sosial Terhadap Kinerja Karyawan Hotel Muria Semarang


    Wihardi, Aditya Nanda; Pradhanawati, Ari; Nugraha, Hari Susanta


    Leadership an employer who responded positively by employees of Hotel Muria Semarang, will be able to grow the assessment that the employer felt able to lead because they have the skills and be able to establish a good relationship with the employees. The working environment is also an impact on employee performance. Environment conducive working atmosphere and full cooperation to further bolster the performance of employees. Phenomenon encountered by researchers baseline data collection, sho...

  18. American Jihadist Terrorism: Combating a Complex Threat (United States)


    66 Jeanne Meserve, “Anti-Terrorism Chief, U.S.-Born Cleric had Major Role in Airline Bombing Try,”, June...program” to bolster its relationship with Arab, Muslim, Sikh, and South Asian communities in the United States.663 Also, in March 2010, Brett Hovington...2010. 664 Brett Hovington, House Committee on Homeland Security, Subcommittee on Intelligence, Information Sharing, and Terrorism Risk Assessment

  19. Ignoring a Revolution in Military Affairs: The Need to Create a Separate Branch of the Armed Forces for Cyber Warfare (United States)


    a need to bolster their militaries cyber capabilities by dedicating a branch of service. China, North Korea, Russia, Norway , and Israel have all...conversations between them and their allies. Upon fleeing the country following his release from prison , Hussain went to Syria and began working with IS...other nations have resulted in the loss of power and commerce. Multiple nations to include North Korea, China, Russia, Israel, and Norway have all

  20. Routines in management accounting research: Further exploration


    Quinn, Martin


    Purpose This paper seeks to enhance the eminent work of Burns and Scapens (2000) by introducing broader conceptualisations on organisational routines and rules in to management accounting. Design/methodology/approach The paper sets out with the Burns and Scapens (2000) framework. The paper is primarily conceptual in nature and with the addition of some more recent literature on organisational routines serves to bolster the underpinnings of the Burns and Scapens (2000) framework. Dra...

  1. Lone-Wolf Terrorist Radicalization and the Prisoner’s Dilemma: Ensuring Mutual Cooperation Between at-Risk Muslim Americans and Local Communities (United States)


    and, presumably to bolster his self - esteem , began to reach out to terrorist organizations in an attempt to belong to a larger cause.134 He began and the need to leave a lasting contribution in the world. During my periods of study and self - reflection, I came across an arresting quote...Success is rarely achieved without the help of a strong support system. Athletes cannot achieve victory without a coach to drive their daily practice, and

  2. Managing stakeholder contestation and negotiation in amenity-driven land-use planning.


    Ness, Jennifer Catherine


    Many destinations are promoting their natural and cultural amenities to attract visitors and bolster their local tourism product. Increasingly, such efforts are associated with inflows of amenity migrants. In many destinations, local amenities are created to facilitate increased tourism and amenity migration. Growing research reveals that meaningful involvement of local residents in planning for tourism and amenity migration can minimize local contestation and negotiation over tourism induced...

  3. Air & Space Power Journal. Volume 29, Number 3, May-June 2015 (United States)


    hospitals to connect patients, providers, and medical (as well as nonmedical [e.g., agricultural]) materiel via a scheduled “ring route.” This cost... hospitals where they not only perform highly specialized opera- tions but also conduct training clinics for all levels of health professionals. Lauded...airports around the nation, and flyers support humanitarian assistance and domestic flying operations, including tourism , to bolster the economy via

  4. Aviation and Health: A Key Nexus for the US Air Force’s Regional Security-Building Efforts (United States)


    would advance through a network of air- strips near medical facilities including both simple dispensaries and hospitals to connect patients...preventive, community- based health care with a focus on public health research.18 AMREF continues to fly surgeons to rural hospitals where they not only...flyers support humanitarian assistance and domestic flying operations, including tourism , to bolster the economy via scheduled and chartered flights

  5. Self-parameterized active contours based on regional edge structure for medical image segmentation


    Mylona, Eleftheria A; Savelonas, Michalis A; Maroulis, Dimitris


    This work introduces a novel framework for unsupervised parameterization of region-based active contour regularization and data fidelity terms, which is applied for medical image segmentation. The work aims to relieve MDs from the laborious, time-consuming task of empirical parameterization and bolster the objectivity of the segmentation results. The proposed framework is inspired by an observed isomorphism between the eigenvalues of structure tensors and active contour parameters. Both may a...

  6. Fueling the Future: Furthering Theater Security with Burma’s Energy Industry (United States)


    and Opportunities 2 China’s FDI in Burma: An Example of “What Not to Do” 5 U.S. FDI in Burma: “Getting it Right” To...realizes external assistance is needed and thus is seeking to attract foreign direct investment ( FDI ) and technical expertise to bolster the industry...Defined by the World Bank, FDI is investment to acquire a lasting management interest in an enterprise operating within an economy other than that of

  7. The dynamics of the three-piece-freight truck

    DEFF Research Database (Denmark)

    Xia, Fujie


    body and the side supports on the bolsters the side supports must be modelled as nonlinear dead-band springs. The clearances in the assembly in the wedge damper systems give rise to a relative yaw motion of the bolster with respect to the side frame and a rotation around the truck center line and cause...... a warping. In addition the assembly clearances between the side frame and the adapter both in longitudinal and lateral directions produce another dead-band spring force. The tractive effort on the car body in the longitudinal direction may be left out of consideration in the modelling of the passenger car...... at all. The motion of the bolsters are at least two dimensional in the lateral and the vertical directions, so the friction on the surfaces of a wedge should be treated as two-dimensional dry friction, and the same is true for the dry friction on the surfaces of an adapter. For the motion with dry...

  8. The Influence of Concentrative Meditation Training on the Development of Attention Networks during Early Adolescence

    Directory of Open Access Journals (Sweden)

    Shruti eBaijal


    Full Text Available We investigate if concentrative meditation training (CMT offered during adolescent development benefits subsystems of attention using a quasi-experimental design. Attentional alerting, orienting, and conflict monitoring were examined using the Attention Network Test (ANT in 13, 14, and 15 yo children who received CMT as part of their school curriculum (CMT Group: N=79 vs. those who received no such training (Control Group: N=76. Alerting and conflict monitoring, but not orienting, differed between the CMT and Control Group. Only conflict monitoring demonstrated age-related improvements, with smaller conflict effect scores in older vs. younger participants. The influence of CMT on this system was similar to the influence of developmental maturity, with smaller conflict effects in the CMT vs. Control group. To examine if CMT might also bolster conflict-triggered upregulation of attentional control, conflict effects were evaluated as a function of previous trial conflict demands (high conflict vs. low conflict. Smaller current trial conflict effects were observed when previous conflict was high vs. low, suggesting that similar to adults, when previous conflict was high (vs. low children in this age-range proactively upregulated control so that subsequent trial performance was benefitted. The magnitude of conflict-triggered control upregulation was not bolstered by CMT but CMT did have an effect for current incongruent trials preceded by congruent trials. Thus, CMT’s influence on attention may be tractable and specific; it may bolster attentional alerting, conflict monitoring and reactive control, but does not appear to improve orienting.

  9. Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model? (United States)

    Ward, Christopher; Ciraulo, David; Coulter, Michael; Desjardins, Steven; Liaw, Lucy; Peterson, Sarah


    Negative-pressure wound therapy (NPWT) has been used for to treat wounds for more than 15 years and, more recently, has been used to secure split-thickness skin grafts. There are some data to support this use of NPWT, but the actual mechanism by which NPWT speeds healing or improves skin graft take is not entirely known. The purpose of this project was to assess whether NPWT improved angiogenesis, wound healing, or graft survival when compared with traditional bolster dressings securing split-thickness skin grafts in a porcine model. We performed two split-thickness skin grafts on each of eight 30 kg Yorkshire pigs. We took graft biopsies on postoperative days 2, 4, 6, 8, and 10 and submitted the samples for immunohistochemical staining, as well as standard hematoxylin and eosin staining. We measured the degree of vascular ingrowth via immunohistochemical staining for von Willenbrand's factor to better identify blood vessel epithelium. We determined the mean cross-sectional area of blood vessels present for each representative specimen, and then compared the bolster and NPWT samples. We also assessed each graft for incorporation and survival at postoperative day 10. Our analysis of the data revealed that there was no statistically significant difference in the degree of vascular ingrowth as measured by mean cross-sectional capillary area (p = 0.23). We did not note any difference in graft survival or apparent incorporation on a macroscopic level, although standard hematoxylin and eosin staining indicated that microscopically, there seemed to be better subjective graft incorporation in the NPWT samples and a nonsignificant trend toward improved graft survival in the NPWT group. We were unable to demonstrate a significant difference in vessel ingrowth when comparing NPWT and traditional bolster methods for split-thickness skin graft fixation. More studies are needed to elucidate the manner by which NPWT exerts its effects and the true clinical magnitude of these

  10. Simplified geometric model for the calculation of neutron yield in an accelerator of 18 MV for radiotherapy

    International Nuclear Information System (INIS)

    Paredes G, L.C.; Balcazar G, M.; Francois L, J.L.; Azorin N, J.


    The results of the neutrons yield in different components of the bolster of an accelerator Varian Clinac 2100C of 18 MV for radiotherapy are presented, which contribute to the radiation of flight of neutrons in the patient and bolster planes. For the calculation of the neutrons yield, a simplified geometric model of spherical cell for the armor-plating of the bolster with Pb and W was used. Its were considered different materials for the Bremsstrahlung production and of neutrons produced through the photonuclear reactions and of electro disintegration, in function of the initial energy of the electron. The theoretical result of the total yield of neutrons is of 1.17x10 -3 n/e, considering to the choke in position of closed, in the patient plane with a distance source-surface of 100 cm; of which 15.73% corresponds to the target, 58.72% to the primary collimator, 4.53% to the levelled filter of Fe, 4.87% to the levelled filter of Ta and 16.15% to the closed choke. For an initial energy of the electrons of 18 MeV, a half energy of the neutrons of 2 MeV was obtained. The calculated values for radiation of experimental neutrons flight are inferior to the maxima limit specified in the NCRP-102 and IEC-60601-201.Ed.2.0 reports. The absorbed dose of neutrons determined through the measurements with TLD dosemeters in the isocenter to 100 cm of the target when the choke is closed one, is approximately 3 times greater that the calculated for armor-plating of W and 1.9 times greater than an armor-plating of Pb. (Author)

  11. Applying a Family-Level Economic Strengthening Intervention to Improve Education and Health-Related Outcomes of School-Going AIDS-Orphaned Children: Lessons from a Randomized Experiment in Southern Uganda. (United States)

    Ssewamala, Fred M; Karimli, Leyla; Torsten, Neilands; Wang, Julia Shu-Huah; Han, Chang-Keun; Ilic, Vilma; Nabunya, Proscovia


    Children comprise the largest proportion of the population in sub-Saharan Africa. Of these, millions are orphaned. Orphanhood increases the likelihood of growing up in poverty, dropping out of school, and becoming infected with HIV. Therefore, programs aimed at securing a healthy developmental trajectory for these orphaned children are desperately needed. We conducted a two-arm cluster-randomized controlled trial to evaluate the effectiveness of a family-level economic strengthening intervention with regard to school attendance, school grades, and self-esteem in AIDS-orphaned adolescents aged 12-16 years from 10 public rural primary schools in southern Uganda. Children were randomly assigned to receive usual care (counseling, school uniforms, school lunch, notebooks, and textbooks), "bolstered" with mentorship from a near-peer (control condition, n = 167), or to receive bolstered usual care plus a family-level economic strengthening intervention in the form of a matched Child Savings Account (Suubi-Maka treatment arm, n = 179). The two groups did not differ at baseline, but 24 months later, children in the Suubi-Maka treatment arm reported significantly better educational outcomes, lower levels of hopelessness, and higher levels of self-concept compared to participants in the control condition. Our study contributes to the ongoing debate on how to address the developmental impacts of the increasing numbers of orphaned and vulnerable children and adolescents in sub-Saharan Africa, especially those affected by HIV/AIDS. Our findings indicate that innovative family-level economic strengthening programs, over and above bolstered usual care that includes psychosocial interventions for young people, may have positive developmental impacts related to education, health, and psychosocial functioning.

  12. Simplified geometric model for the calculation of neutron yield in an accelerator of 18 MV for radiotherapy; Modelo geometrico simplificado para el calculo del rendimiento de neutrones en un acelerador de 18 MV para radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Paredes G, L.C.; Balcazar G, M. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico); Francois L, J.L. [FI-UNAM, 04510 Mexico D.F. (Mexico); Azorin N, J. [UAM-I, 09340 Mexico D.F. (Mexico)


    The results of the neutrons yield in different components of the bolster of an accelerator Varian Clinac 2100C of 18 MV for radiotherapy are presented, which contribute to the radiation of flight of neutrons in the patient and bolster planes. For the calculation of the neutrons yield, a simplified geometric model of spherical cell for the armor-plating of the bolster with Pb and W was used. Its were considered different materials for the Bremsstrahlung production and of neutrons produced through the photonuclear reactions and of electro disintegration, in function of the initial energy of the electron. The theoretical result of the total yield of neutrons is of 1.17x10{sup -3} n/e, considering to the choke in position of closed, in the patient plane with a distance source-surface of 100 cm; of which 15.73% corresponds to the target, 58.72% to the primary collimator, 4.53% to the levelled filter of Fe, 4.87% to the levelled filter of Ta and 16.15% to the closed choke. For an initial energy of the electrons of 18 MeV, a half energy of the neutrons of 2 MeV was obtained. The calculated values for radiation of experimental neutrons flight are inferior to the maxima limit specified in the NCRP-102 and IEC-60601-201.Ed.2.0 reports. The absorbed dose of neutrons determined through the measurements with TLD dosemeters in the isocenter to 100 cm of the target when the choke is closed one, is approximately 3 times greater that the calculated for armor-plating of W and 1.9 times greater than an armor-plating of Pb. (Author)

  13. Breaking the silence on abortion: the role of adult community abortion education in fostering resistance to norms. (United States)

    Bloomer, Fiona K; O'Dowd, Kellie; Macleod, Catriona


    Meanings of abortion in society are constructed within sociohistorical and gendered spaces and manifested through myriad discourses that impact on the perception and treatment of the issue in that society. In societies with powerful oppressive anti-abortion norms, such as Northern Ireland, little is known as to how these norms are resisted by the adult population. This study uses a Foucauldian feminist approach to show how resistance to religious and patriarchal norms can be fostered through adult community abortion education. This resistance is multi-faceted and bolstered by a lived experience discourse, which does not necessarily involve eschewing religious notions held within society.

  14. Book Reviews


    Redactie KITLV


    -Charles V. Carnegie, W. Jeffrey Bolster, Black Jacks: African American Seamen in the age of sail. Cambridge MA: Harvard University Press, 1997. xiv + 310 pp. -Stanley L. Engerman, Wim Klooster, Illicit Riches: Dutch trade in the Caribbean, 1648-1795. Leiden: KITLV Press, 1998. xiv + 283 pp. -Luis Martínez-Fernández, Emma Aurora Dávila Cox, Este inmenso comercio: Las relaciones mercantiles entre Puerto Rico y Gran Bretaña 1844-1898. San Juan: Editorial de la Universidad de Puerto Rico, 1996. ...

  15. Philippines' downstream sector poised for growth

    International Nuclear Information System (INIS)



    This paper reports that the Philippines' downstream sector is poised for sharp growth. Despite a slip in refined products demand in recent years, Philippines products demand will rebound sharply by 2000, East-West Center (EWC), Honolulu, predicts. Philippines planned refinery expansions are expected to meet that added demand, EWC Director Fereidun Fesharaki says. Like the rest of the Asia-Pacific region, product specifications are changing, but major refiners in the area expect to meet the changes without major case outlays. At the same time, Fesharaki says, push toward deregulation will further bolster the outlook for the Philippines downstream sector

  16. Cue-evoked positive affect, depression vulnerability and smoking years. (United States)

    McChargue, Dennis E; Doran, Neal


    To evaluate whether cue-evoked affective response would moderate the relationship between depression-proneness and smoking years. Depression-proneness profiles were derived using clinician diagnosed personal and family histories of major depression, recurrent depression, trait-anhedonia, and ruminative coping styles (n=70). Affective distress was produced by idiographic, guided negative mood imageries in the presence of an in vivo cigarette exposure. Contrary to expectations, results showed that individuals less vulnerable to depression reported longer smoking histories. Stress-induced decreases in positive affect bolstered the association between depression vulnerability and smoking years. Depression-proneness assumptions are challenged and implications to affective influences on smoking behavior are discussed.

  17. ISES International Solar Energy Society: Italian Section report

    International Nuclear Information System (INIS)

    Sesto, E.; Stancampiano, M.


    After a brief introduction highlighting the potential benefits to be derived from the suitable application of wind turbines, in terms of economic and environmentally compatible energy supplies for remote areas, this paper gives a panoramic look at wind turbine commercialization activities in Italy. The main manufacturers and technical characteristics of the three most promising wind turbines are reported. Comments are made on world market trends and incentive programs being developed by the Italian Government and the European Communities to help bolster industrial participation in this sector

  18. Iran’s Balancing Act in Afghanistan (United States)


    Bolster Afghanistan Rebuilding Efforts,” Christian Science Monitor, April 3, 2009. As of January 5, 2011: 235–256. Mulrine, Anna, “NATO General: We Can Hand Off Some Districts to Afghan Forces Now,” Christian Science Monitor, September 30, 2010. As of...Nader, Lydia Hansell , Rasool Nafisi, and S. R. Bohandy, The Rise of the Pasdaran: Assessing the Domestic Roles of Iran’s Islamic Revolutionary Guards

  19. Continuity and Rupture in the Growth of Cultures

    Directory of Open Access Journals (Sweden)

    Jaume Botey Vallès


    Full Text Available The first part of the article deals with the classical concepts of identity, diversity and pluralism in relation to present societies in conflict. The second part addresses specifically the case of the Andalusian immigration to Catalonia from 1955 to 1975 and the hardening relations and tensions between the two communities in present-day Catalonia. Finally, in the presence of economic globalization and the bolstered emergence of new identities, some of which have religious aspects as significant components, a proposition is put forth to find common ground in the new social movements and religious faith as two arenas of intercultural negotiation.

  20. Cost-time management: A powerful tool in a new application - cleaning up the weapons complex

    International Nuclear Information System (INIS)

    Gallagher, J.L.


    Westinghouse Electric Corporation is aggressively applying cost-time management to bolster timely, cost-effective cleanup and waste management activities at sites it manages for the U.S. Department of Energy (DOE). Cost-time management is a diagnostic technique which is applicable to virtually any process. It identifies opportunities to reduce cycle-times and costs. When applied to cleanup and waste management at DOE facilities, cost-time profile analysis helps identify actions to improve productivity and quality. Moreover, by reducing cycle-times and costs, it achieves significant savings to taxpayers. (author)

  1. Fasting: Molecular Mechanisms and Clinical Applications (United States)

    Longo, Valter D.; Mattson, Mark P.


    Fasting has been practiced for millennia, but only recently studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism and bolster cellular protection. In lower eukaryotes, chronic fasting extends longevity in part by reprogramming metabolic and stress resistance pathways. In rodents intermittent or periodic fasting protects against diabetes, cancers, heart disease and neurodegeneration, while in humans it helps reduce obesity, hypertension, asthma and rheumatoid arthritis. Thus, fasting has the potential to delay aging and help prevent and treat diseases while minimizing the side effects caused by chronic dietary interventions. PMID:24440038

  2. Nuclear waste dumping in the oceans: Has the Cold War taught us anything?

    Energy Technology Data Exchange (ETDEWEB)

    Moody-O`Grady, K.


    The United States and other international actors have relied without much success on traditional approaches to contain environmental damage done to our oceans by Russian dumping of nuclear waste. Our arms control experience suggests that on-site inspection is successful in situations where there is a lack of information or a lack of trust. Using on-site inspection to gather information and bolster trust could ameliorate the problem of Russian dumping of radioactive wastes into the ocean, so long as the political and financial costs of on-site inspection do not prove to be prohibitively high.

  3. Building Cross-Country Networks for Laboratory Capacity and Improvement. (United States)

    Schneidman, Miriam; Matu, Martin; Nkengasong, John; Githui, Willie; Kalyesubula-Kibuuka, Simeon; Silva, Kelly Araujo


    Laboratory networks are vital to well-functioning public health systems and disease control efforts. Cross-country laboratory networks play a critical role in supporting epidemiologic surveillance, accelerating disease outbreak response, and tracking drug resistance. The East Africa Public Health Laboratory Network was established to bolster diagnostic and disease surveillance capacity. The network supports the introduction of regional quality standards; facilitates the rollout and evaluation of new diagnostic tools; and serves as a platform for training, research, and knowledge sharing. Participating facilities benefitted from state-of-the art investments, capacity building, and mentorship; conducted multicountry research studies; and contributed to disease outbreak response. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Metathesis access to monocyclic iminocyclitol-based therapeutic agents

    Directory of Open Access Journals (Sweden)

    Albert Demonceau


    Full Text Available By focusing on recent developments on natural and non-natural azasugars (iminocyclitols, this review bolsters the case for the role of olefin metathesis reactions (RCM, CM as key transformations in the multistep syntheses of pyrrolidine-, piperidine- and azepane-based iminocyclitols, as important therapeutic agents against a range of common diseases and as tools for studying metabolic disorders. Considerable improvements brought about by introduction of one or more metathesis steps are outlined, with emphasis on the exquisite steric control and atom-economical outcome of the overall process. The comparative performance of several established metathesis catalysts is also highlighted.

  5. Comptia Network+ review guide exam N10-006

    CERN Document Server

    Ferguson, Bill


    Be prepared for the Network+ exam CompTIA Network+ Review Guide is your ideal study companion for preparing for the CompTIA Network+ exam (N10-006). This concise review is the perfect companion to the CompTIA Network+ Study Guide and the CompTIA Network+ Deluxe Study Guide, with full exam coverage organized by objective for quick review and reinforcement of key topics. Each of the book's five parts is devoted to a specific domain area of the exam, providing a focused review to bolster areas of weak understanding. You get access to the Sybex test engine, which includes two bonus practice tests

  6. ``Global Warming/Climate Change'': A Critical Look (United States)

    Gould, Laurence I.


    There continues to be an increasing number of scientists from around the world who are challenging the dominant claim that has been bolstered by so-called ``consensus'' scientific views -- that dangerous ``global warming/climate change'' is caused primarily by human-produced carbon dioxide. This poster will show scientific evidence contradicting that claim. It will also explain some of the errors that have been introduced from a corruption of the scientific method. (Further information can be found at

  7. Undertaking and writing research that is important, targeted, and the best you can do. (United States)

    McLeod, Sharynne


    Conducting and writing research is a privilege. It is a privilege because researchers can change lives through their findings and can influence public knowledge and debate. It is also a privilege because researchers are reliant on the time and goodwill of participants (and colleagues), and research is often underpinned by funding raised by the public, either through taxes or philanthropic donations. This privilege comes with responsibility. Researchers have a responsibility to undertake research that is important, targeted, and of high quality. This editorial aims to inspire, challenge, and bolster the research efforts of individuals and teams.

  8. An agenda for increasing grant funding of emergency medicine education research. (United States)

    Choo, Esther K; Fernandez, Rosemarie; Hayden, Emily M; Schneider, Jeffrey I; Clyne, Brian; Ginsburg, Shiphra; Gruppen, Larry D


    Funding is a perennial challenge for medical education researchers. Through a consensus process, the authors developed a multifaceted agenda for increasing funding of education research in emergency medicine (EM). Priority agenda items include developing resources to increase the competitiveness of medical education research faculty in grant applications, identifying means by which departments may bolster their faculty's grant writing success, taking long-term steps to increase the number of grants available to education researchers in the field, and encouraging a shift in cultural attitudes toward education research. © 2012 by the Society for Academic Emergency Medicine.

  9. Panic disorder: the psychobiology of external treat and introceptive distress. (United States)

    Stein, Dan J


    Panic disorder seems to be mediated by the neuronal circuitry and neurochemical systems that have evolved to respond to external threatening stimuli. Distant threats activate prefrontal cortex (involved in complex planning of avoidance strategies), while immediate threats activate midbrain structures (involved in fast reflexive behaviors). Panic disorder may, however, also involve more specific interoceptive mechanisms. For example, the association between respiratory dysfunction and panic disorder has bolstered a false suffocation alarm hypothesis. Genetic and environmental contributors to panic disorder are beginning to be delineated. Effective pharmacotherapy and psychotherapy are able to normalize the relevant psychobiology.

  10. Education and Training in Radiochemistry -- The NAMP Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Patricia Paviet-Hartmann; Mansour Akbarzadeh


    A number of reports have indicated that a sizable percentage of the nation’s experts in radiochemistry are nearing retirement age. This reality has been a concern since the 1970s, when declining numbers of radiochemists worldwide was first observed. Therefore, the NAMP (National Analytical Management Program) has organized a subcommittee focused on training and education in radiochemistry. To bolster interest and increase awareness in radiochemistry, NAMP is offering webinars developed by experts on different topics relevant to radiochemistry. This paper presents our accomplishments in developing these webinars and highlights our efforts in outreaching the national and international radiochemistry community.

  11. Virtual realities: The use of violent video games in U.S. military recruitment and treatment of mental disability caused by war

    Directory of Open Access Journals (Sweden)

    John Derby


    Full Text Available This article critically analyzes the U.S. military's contradictory use of violent video gaming technologies for recruiting young gamers to the military, training soldiers for combat, and clinically treating soldiers for posttraumatic stress disorder (PTSD caused by military service. Using a Disability Studies lens, I discuss the commercial video game Full Spectrum Leader/Warrior, the U.S. Army's free video game America's Army, and the virtual reality exposure therapy application Virtual Iraq. I also discuss missions and omissions from the literature on these gaming technologies, which bolsters the underlying ableism of military culture that inhibits soldiers from recovering from PTSD.

  12. NPRA meeting checks the pulse of the petrochemical industry

    Energy Technology Data Exchange (ETDEWEB)

    Hunter, D.; Young, I.; Wood, A.


    The Globalization of Petrochemicals was the rather hackneyed theme of last week`s National Petroleum Refiners Association (NPRA) international petrochemical conference in San Antonio. But though petrochemicals may be taking on a more global character, the mood of delegates from different parts of the world was sharply different. There was a perceptible feeling of confidence among US delegates, that the current beginnings of an uptick in the economy will bolster the petrochemical business. Producers report that volumes are up during the first quarter and inventories are tightening, providing the backdrop for price initiatives during the second quarter that might this time have a chance of sticking.

  13. Insights into the Ukrainian Crisis

    Directory of Open Access Journals (Sweden)

    Costel Daniel Arfire


    Full Text Available Political crises are increasingly frequent and devastating not only for the population of a state, but also for the international diplomacy. Such an example is the ongoing Ukrainian crisis. Starting from S. Fink‘s life cycle of a crisis and T.W. Coombs‘s crisis response strategies, I will analyse the evolution of the Ukrainian crisis and the crisis response strategies of three major international actors: Vladimir Putin, Barack Obama and Angela Merkel. The findings of my study will prove that the denial strategy prevails in Putin‘s statement, whereas Obama uses the diminish strategy and Merkel focuses on the bolstering strategy.

  14. The LHCb analysis for $B_{s} \\to \\mu^{+}\\mu^{-}$

    CERN Document Server

    Bettler, Marc-Olivier


    LHCb, bolstered up by the $10^{12}$ $b$-hadrons produced yearly, is an excellent place to study rare $B$ decays. The $B^0_s \\to \\mu^+ \\mu^-$ decay, generated by flavour-changing neutral current, is strongly suppressed within the Standard Model (SM). However, its branching ratio can be significantly enhanced if New Physics (NP) exists. The current best limit is still an order of magnitude above the SM prediction, thus leaving room for observation of NP effects. In this document, the current LHCb analysis strategy for the $B^0_s \\to \\mu^+ \\mu^-$ search is presented.

  15. Instant Citrix security how-to

    CERN Document Server

    Jacob, Carmel


    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Get the job done and learn as you go. A how-To book with practical recipes accompanied with rich screenshots for easy comprehension.This easy-to-follow, hands-on guide shows you how to bolster your security with real life cases and step-by-step instructions.This guide gets new users up and running with Citrix Netscaler in simple practical steps and also acts as a refresher to those with some experience of the product and its features.

  16. Purifying Impure Virtue Epistemology

    DEFF Research Database (Denmark)

    Broncano-Berrocal, Fernando


    A notorious objection to robust virtue epistemology—the view that an agent knows a proposition if and only if her cognitive success is because of her intellectual virtues—is that it fails to eliminate knowledge-undermining luck. Modest virtue epistemologists agree with robust virtue epistemologists...... instances of impure virtue epistemology. The aim of the paper is to argue, firstly, that such a move lacks adequate motivation; secondly, that the resulting impure accounts equally fail to handle knowledge-undermining luck. On a more positive note, these results bolster a more orthodox virtue...

  17. Joomla! 25 Beginner's Guide

    CERN Document Server

    Tiggeler, Eric


    Written with a fast-paced but friendly and engaging approach, this Packt Beginner's guide is designed to be placed alongside the computer as your guide and mentor. Step-by-step tutorials are bolstered by explanations of the reasoning behind what you are doing. You will quickly pick up the necessary skills, tips, and tricks for building a successful Joomla! website. This book is written for beginners to website design. By the end of the book you will have built a complete custom content managed website, and be ready to build any kind of website.

  18. Ensuring medical device effectiveness and safety: a cross--national comparison of approaches to regulation. (United States)

    Kramer, Daniel B; Tan, Yongtian T; Sato, Chiaki; Kesselheim, Aron S


    Regulatory bodies weighing market approval for novel medical devices must balance the benefits and potential hazards carefully. We performed a legal and policy review of appraoches in the US, EU, Japan, and China to device regulation with a focus on postmarket surveillance. These markets share broad features such as a heavy reliance on passive adverse event collection, reflected by growing enthusiasm for more active and dynamic mechanisms such as unique device identification. More immediately, US and EU systems might benefit from scheduled, compulsory, and consequential re-examination of select devices, as is done in Japan and China, in order to strengthen post-market protection of patients and bolster public health.

  19. Resident Archive Services of the Yohkoh Legacy Data Archive

    Directory of Open Access Journals (Sweden)

    A Takeda


    Full Text Available The Yohkoh Legacy Data Archive (YLA is one of the first group of Resident Archives (RAs selected for funding for NASA's Virtual Observatories for the Heliophysics Data program. YLA provides the best corrected data set of solar X-ray images and spectra from the Yohkoh satellite with a user-friendly web interface. As a RA, we take responsibility to keep our products well maintained and easily accessible. In addition, we have launched the 'E-consultant service', an e-mail based support to individual users regarding data handling to bolster access and use from a wide range of communities.

  20. CERN and the Wigner Research Centre for Physics inaugurate CERN data centre’s extension in Budapest, Hungary

    CERN Multimedia

    Wigner Research Centre for Physics, Hungary


    On 13 June 2013 CERN and the Wigner Research Centre for Physics inaugurated the Hungarian data centre in Budapest, marking the completion of the facility hosting the extension for CERN computing resources. About 500 servers, 20,000 computing cores, and 5.5 Petabytes of storage are already operational at the site. The dedicated and redundant 100 Gbit/s circuits connecting the two sites are functional since February 2013 and are among the first transnational links at this distance. The capacity at Wigner will be remotely managed from CERN, substantially extending the capabilities of the Worldwide LHC Computing Grid (WLCG) Tier-0 activities and bolstering CERN’s infrastructure business continuity.

  1. Molecular evidence for a terrestrial origin of snakes (United States)

    Vidal, Nicolas; Hedges, S. Blair


    Biologists have debated the origin of snakes since the nineteenth century. One hypothesis suggests that snakes are most closely related to terrestrial lizards, and reduced their limbs on land. An alternative hypothesis proposes that snakes are most closely related to Cretaceous marine lizards, such as mosasaurs, and reduced their limbs in water. A presumed close relationship between living monitor lizards, believed to be close relatives of the extinct mosasaurs, and snakes has bolstered the marine origin hypothesis. Here, we show that DNA sequence evidence does not support a close relationship between snakes and monitor lizards, and thus supports a terrestrial origin of snakes.

  2. Self-parameterized active contours based on regional edge structure for medical image segmentation. (United States)

    Mylona, Eleftheria A; Savelonas, Michalis A; Maroulis, Dimitris


    This work introduces a novel framework for unsupervised parameterization of region-based active contour regularization and data fidelity terms, which is applied for medical image segmentation. The work aims to relieve MDs from the laborious, time-consuming task of empirical parameterization and bolster the objectivity of the segmentation results. The proposed framework is inspired by an observed isomorphism between the eigenvalues of structure tensors and active contour parameters. Both may act as descriptors of the orientation coherence in regions containing edges. The experimental results demonstrate that the proposed framework maintains a high segmentation quality without the need of trial-and-error parameter adjustment.

  3. Android Robot-Mediated Mock Job Interview Sessions for Young Adults with Autism Spectrum Disorder: A Pilot Study


    Kumazaki, Hirokazu; Warren, Zachary; Corbett, Blythe A.; Yoshikawa, Yuichiro; Matsumoto, Yoshio; Higashida, Haruhiro; Yuhi, Teruko; Ikeda, Takashi; Ishiguro, Hiroshi; Kikuchi, Mitsuru


    The feasibility and preliminary efficacy of an android robot-mediated mock job interview training in terms of both bolstering self-confidence and reducing biological levels of stress in comparison to a psycho-educational approach human interview was assessed in a randomized study. Young adults (ages 18–25 years) with autism spectrum disorder (ASD) were randomized to participate either in a mock job interview training with our android robot system (n = 7) or a self-paced review of materials ab...

  4. Implementation Of 5S Quality Tool In Manufacturing Company A Case Study

    Directory of Open Access Journals (Sweden)

    Vibhor Kakkar


    Full Text Available Abstract 5S system is a technique which maintains the quality of working conditions in the organization. Amongst various available Lean resources 5S is a powerful technique that can bolster objectives of the organization to get continuous improvement in performance and productivity. This paper presents the implementation of 5S in a manufacturing company amp 5S rating system was used to audit all changes in the company which enhanced the efficiency of the workers amp ultimately the productivity of the company is enhanced to 91 .

  5. Nuclear waste dumping in the oceans: Has the Cold War taught us anything?

    International Nuclear Information System (INIS)

    Moody-O'Grady, K.


    The United States and other international actors have relied without much success on traditional approaches to contain environmental damage done to our oceans by Russian dumping of nuclear waste. Our arms control experience suggests that on-site inspection is successful in situations where there is a lack of information or a lack of trust. Using on-site inspection to gather information and bolster trust could ameliorate the problem of Russian dumping of radioactive wastes into the ocean, so long as the political and financial costs of on-site inspection do not prove to be prohibitively high

  6. Operational Group Sandy technical progress report (United States)



    Hurricane Sandy made US landfall near Atlantic City, NJ on 29 October 2012, causing 72 direct deaths, displacing thousands of individuals from damaged or destroyed dwellings, and leaving over 8.5 million homes without power across the northeast and mid-Atlantic. To coordinate federal rebuilding activities in the affected region, the President established the cabinet-level Hurricane Sandy Rebuilding Task Force (Task Force). The Task Force was charged with identifying opportunities for achieving rebuilding success while supporting economic vitality, improving public health and safety, protecting and enhancing natural and manmade infrastructure, bolstering resilience, and ensuring appropriate accountability.

  7. Mindfulness Among Genetic Counselors Is Associated with Increased Empathy and Work Engagement and Decreased Burnout and Compassion Fatigue. (United States)

    Silver, Julia; Caleshu, Colleen; Casson-Parkin, Sylvie; Ormond, Kelly


    Genetic counselors experience high rates of compassion fatigue and an elevated risk for burnout, both of which can negatively impact patient care and retention in the profession. In other healthcare professions, mindfulness training has been successfully used to address similar negative psychological sequelae and to bolster empathy, which is the foundation of our counseling work. We aimed to assess associations between mindfulness and key professional variables, including burnout, compassion fatigue, work engagement, and empathy. Data were collected via an anonymous, online survey that included validated measures of mindfulness and these key professional variables. The survey was completed by 441 genetic counselors involved in direct patient care. Half of the respondents (50.1%) reported engaging in yoga, meditation, and/or breathing exercises. Mindfulness was positively correlated with work engagement (r = 0.24, p burnout (r = - 0.50, p < 0.001). Given these findings, mindfulness training may be a valuable addition to graduate and continuing education for genetic counselors. The integration of mindfulness into the genetic counseling field will likely improve professional morale and well-being, while promoting workforce retention and bolstering the relational and counseling aspects of our clinical work.

  8. Subsidy as an agent to enhance the effectiveness of the energy performance certificate

    International Nuclear Information System (INIS)

    McGilligan, Charles; Sunikka-Blank, Minna; Natarajan, Sukumar


    Since more than two-thirds of the United Kingdom housing stock in 2050 will comprise houses that have already been built, the need for a focus of policy on the already-built private housing stock is apparent. This study examines the impact that subsidy can make in bolstering the performance of the Energy Performance Certificate by reducing carbon emissions in the residential sector. The results of a survey of new homeowners' uptake of nine commonly installed energy saving measures in response to subsidy are examined. A cost-benefit analysis is performed using the recently introduced concept of the Shadow Price of Carbon and a model is presented which allows the carbon savings for any level of subsidy to be calculated. The model suggests that subsidisation of the installation of hot water tank insulation, draught proofing measures, loft insulation and cavity wall insulation may be cost-effective, but that the subsidisation of others, most notably interior solid wall insulation, are unlikely to significantly bolster carbon savings.

  9. Ohmic ignition with high engineering beta based on the RFP (United States)

    Sarff, J. S.; Anderson, J. K.; Chapman, B. E.; McCollam, K. J.


    The RFP configuration allows the possibility of ohmic ignition for fusion energy, eliminating the need for auxiliary heating by rf or neutral beam injection. Complex plasma-facing antennas and NBI sources are therefore not required, simplifying the difficult fusion materials challenge. While all toroidal configurations require a volume-average 〈 B 〉 >= 5 T, the field strength at the magnet in the RFP is only Bcoil 3T since plasma current generates almost all of the field. Engineering beta is therefore maximized. We summarize access to ohmic ignition by examining a Lawson-like power balance for an RFP fusion plasma comparable to the ARIES-AT advanced tokamak, which generates neutron wall loading Pn / A 5 MW/m2. The required energy confinement for ohmic ignition in an RFP is similar to that for a tokamak. Confinement in MST is comparable to a same-size, same-field tokamak plasma, but 〈 B 〉 in MST is only 1/20th that required for fusion. While transport could ultimately be dominated by micro turbulence, extrapolation of stochastic transport using Lundquist number scaling for MHD tearing indicates standard RFP confinement (not enhanced by current profile control) could be sufficient to access ohmic ignition. This bolsters the possibility for steady-state inductive sustainment using oscillating field current drive. The high beta and classical energetic ion confinement measured in MST also bolster the RFP's fusion potential. Work supported by U.S. DoE.

  10. A novel technique for treating auricular hematomas in mixed martial artists (ultimate fighters). (United States)

    Roy, Soham; Smith, Lee P


    This study aimed to describe a "bolsterless" technique for managing auricular hematomas in professional fighters. Eight auricular hematomas were drained under local anesthesia by incising along an anatomical auricular crease. After evacuation of the hematoma and copious irrigation, the resultant skin flap was replaced in anatomical position, and through-and-through absorbable mattress sutures were used to secure the flap in place. Incision sites were left open and dressed with antimicrobial ointment. No bolsters were placed. The patients were given 1 week of oral antibiotic therapy. All 8 hematomas resolved without further intervention. All 8 ears returned to their preinjury cosmetic state. Fighters were able to return to training within a week of the initial injury. No postoperative infections or other complications were noted. In contrast to wrestlers, mixed martial artists (also called "ultimate fighters") do not routinely wear protective head gear. As a result, they are at increased risk of recurrent auricular hematomas, often resulting in severe auricular deformities (cauliflower ear). These patients are anxious to return to training and fighting, and are reluctant to wear a bolster after repair. At their urging, we agreed to attempt this bolsterless technique. Although 2 patients in this series already had a significant cauliflower ear before being treated for the current hematoma, in all cases the auricle returned to its preinjury condition. Bolsterless treatment using mattress sutures and cosmetically placed incisions represents a successful technique for management of auricular hematomas in this population.


    Directory of Open Access Journals (Sweden)

    L. A. Muradian


    Full Text Available Purpose. The scientific work is aimed to: 1 analyze the technical condition of freight cars and technological methods used in the repair; 2 identify possible ways to improve resource of freight car bogies; 3 develop a mathematical model to describe the wear geometry of the original surface of bogie center pad at the corresponding life cycle of a freight car. Methodology. In order to solve the problem complex of increasing TBO of freight car bogies the methods for the synthesis, analysis and systematic approach were used. In addition, the use of mathematical modeling unit, solid state physics, the theory of friction and wear of solids. Findings. The analysis of the technical condition of freight cars has shown that up to 15% of the faults falls on the bogies. A separate element of the repaired bogie is a bolster. At this the center pad is recovered most often. The center pad wear is uneven and the technological methods used for the repair, do not allow providing uniform wear due to which there is a need in premature repairs. One of the ways to improve the center pad resource during repair is the application of welding or sputtering deposition, but with providing discrete strength and durability in the longitudinal and transverse directions of the car axis, respectively. In order to establish the boundaries of the distribution of renewable material along the center pad diameter it was considered the fatigue wear process in cooperation with center plate and described the geometry of the surface of the center pad wear. Originality. Technical condition of freight car bogies according to wear criterion was analyzed in the paper. It is shown that the dynamics of bogie faults has a positive character. In addition, a significant place among the repaired parts takes the bolster, and a special loaded place is the center pad. To describe the geometry of wear for the first time a mathematical model for determining the initial surface of the center pad in the

  12. Assessing the religious roots of volunteer work in middle and late life. (United States)

    Krause, Neal


    Research reveals that older people do a significant amount of volunteer work. Moreover, a good deal of this volunteering takes place in religious institutions. The purpose of this study is to examine how social factors in the church influence the decision to volunteer. The analyses are conducted in two steps. First, data from a longitudinal nationwide survey of older people are used to show that increases in spiritual support (i.e., assistance from fellow church members that is designed to bolster religious beliefs and behaviors) are associated with increases in the frequency of volunteer work. Second, cross-sectional analyses from the same survey suggest that spiritual support is associated with volunteering in part because it promotes greater compassion. However, the magnitude of the relationship between compassion and volunteering is fairly modest. © The Author(s) 2014.

  13. The importance of parents and other caregivers to the resilience of high-risk adolescents. (United States)

    Ungar, Michael


    Relationships between 43 high-risk adolescents and their caregivers were examined qualitatively. Parents and other formal and informal caregivers such as youth workers and foster parents were found to exert a large influence on the behaviors that bolster mental health among high-risk youth marginalized by poverty, social stigma, personal and physical characteristics, ethnicity, and poor social or academic performance. Participants' accounts of their intergenerational relationships with caregivers showed that teenagers seek close relationships with adults in order to negotiate for powerful self-constructions as resilient. High-risk teens say they want the adults in their lives to serve as an audience in front of whom they can perform the identities they construct both inside and outside their homes. This pattern was evident even among youth who presented as being more peer-than family-oriented. The implications of these findings to interventions with caregivers and teens is discussed.

  14. Gallinacin and Fowlicidin: Two Promising Antimicrobial Peptides in ChickensAND#8212;A Review

    Directory of Open Access Journals (Sweden)

    C. S. Mukhopadhyaya


    Full Text Available Antimicrobial peptides (AMP which have been identified in almost all groups of organisms, are the small cationic molecules that recognize the pathogen associated molecular patterns of the microbes. In chicken two main AMPs that play significant roles in bolstering the innate immunity are gallinacins and fowlicidins, which are the functional analogues of the mammalian beta-defensins and cathelicidins. Gallinacin identifies the Gram negative bacteria while fowlicidin exerts broad spectral activity. The basic mechanism of action is by far similar in both groups of AMPs. The ‘docking sites’ of these antimicrobial peptides includes the “lipid A” moiety of lipo polysaccharides, lipo-teichoic acids, anionic membrane phospholipids on bacterial surfaces. These AMPs block the DNA replication and protein synthesis in bacteria causing death of the microbe. Researchers have identified reproducible molecular markers of those peptides for selection of disease resistant stock of chickens. [Vet. World 2010; 3(6.000: 297-300

  15. Institutional profile of pharmacogenetics within University of Michigan College of Pharmacy. (United States)

    Hertz, Daniel L; Luzum, Jasmine A; Pasternak, Amy L; Ward, Kristen M; Zhu, Hao-Jie; Rae, James M; Ellingrod, Vicki L


    The University of Michigan College of Pharmacy has made substantial investment in the area of pharmacogenomics to further bolster its activity in pharmacogenomics research, implementation and education. Four tenure-track faculty members have active research programs that focus primarily on the discovery of functional polymorphisms (HJ Zhu), and genetic associations with treatment outcomes in patients with cancer (DL Hertz), cardiovascular disease (JA Luzum) and psychiatric conditions (VL Ellingrod). Recent investments from the University and the College have accelerated the implementation of pharmacogenetics broadly across the institution and in targeted therapeutic areas. Students within the PharmD and other health science professions receive substantial instruction in pharmacogenomics, in preparation for careers in biomedical health in which they can contribute to the generation, dissemination and utilization of pharmacogenomics knowledge to improve patient care.

  16. Correlates of service delivery and social environment in adult day service programs. (United States)

    Gaugler, Joseph E


    The objectives of this study were to better describe adult day service (ADS) programs and determine how various structural and case mix characteristics of ADS were empirically associated with the services provided in and the social environments of adult day programs. All directors of ADS programs in Minnesota (United States) were contacted from 2011 to 2012 to complete a detailed online survey that collected information on ADS structure, client case mix, services and activities, and social environment (n = 83; 67.5% response rate). Several structural characteristics and case mix indicators (e.g., number of clients attending) were significantly associated (p social environment. The results suggest the potential need for bolstering staffing and enhancing the physical environment of ADS programs.

  17. Purpose in life as a resource for increasing comfort with ethnic diversity. (United States)

    Burrow, Anthony L; Stanley, Maclen; Sumner, Rachel; Hill, Patrick L


    Emerging demographic trends signal that White Americans will soon relinquish their majority status. As Whites' acclimation to an increasingly diverse society is poised to figure prominently in their adjustment, identifying sources of greater comfort with diversity is important. Three studies (N = 519) revealed evidence that purpose in life bolsters comfort with ethnic diversity among White adults. Specifically, dispositional purpose was positively related to diversity attitudes and attenuated feelings of threat resulting from viewing demographic projections of greater diversity. In addition, when primed experimentally, purpose attenuated participants' preferences for living in an ethnically homogeneous-White city, relative to a more diverse city when shown maps displaying ethno-demographic information. These effects persisted after controlling for positive affect and perceived connections to ethnic out-groups, suggesting the robust influence of purpose. Potential benefits of situating purpose as a unique resource for navigating an increasingly diverse society are discussed. © 2014 by the Society for Personality and Social Psychology, Inc.

  18. Providing meaningful care: learning from the experiences of suicidal young men. (United States)

    Jordan, Joanne; McKenna, Hugh; Keeney, Sinead; Cutcliffe, John; Stevenson, Chris; Slater, Paul; McGowan, Iain


    Little is known about young suicidal men's preferences for care. Using a broad interpretive approach, we interviewed 36 formerly suicidal young men in a study addressing the development and provision of mental health services. Our analysis yielded three core categories: widening access and bolstering proactive outreach, on becoming a man, and equipping young men for future challenges. Collectively, these categories suggest key features and processes of appropriate service configuration and clinical care: (a) services that reach out proactively serve to encourage young men's initial and ongoing engagement; (b) care delivered over the long term ensures a necessary focus on a meaningful future life; (c) mental health professionals (MHPs) are centrally involved alongside significant others, including those with personal experience of suicide; and (d) the development of a vital interpersonal connection is based on MHPs actively communicating their empathy, open-mindedness, and interest in a young man's unique biography.

  19. NAD+ in Aging: Molecular Mechanisms and Translational Implications. (United States)

    Fang, Evandro F; Lautrup, Sofie; Hou, Yujun; Demarest, Tyler G; Croteau, Deborah L; Mattson, Mark P; Bohr, Vilhelm A


    The coenzyme NAD + is critical in cellular bioenergetics and adaptive stress responses. Its depletion has emerged as a fundamental feature of aging that may predispose to a wide range of chronic diseases. Maintenance of NAD + levels is important for cells with high energy demands and for proficient neuronal function. NAD + depletion is detected in major neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, cardiovascular disease and muscle atrophy. Emerging evidence suggests that NAD + decrements occur in various tissues during aging, and that physiological and pharmacological interventions bolstering cellular NAD + levels might retard aspects of aging and forestall some age-related diseases. Here, we discuss aspects of NAD + biosynthesis, together with putative mechanisms of NAD + action against aging, including recent preclinical and clinical trials. Published by Elsevier Ltd.

  20. HIV-negative and HIV-discordant Gay Male Couples’ Use of HIV Risk-Reduction Strategies: Differences by Partner Type and Couples’ HIV-status (United States)

    Mitchell, Jason W.


    Previous research has found that gay men and other men who have sex with men (MSM) have adopted a variety of HIV risk-reduction strategies to engage in unprotected anal intercourse (UAI). However, whether gay male couples’ use these strategies within and out of their relationships remains unknown. The present national cross-sectional study collected dyadic data from an online sample of 275 HIV-negative and 58 discordant gay male couples to assess their use of these strategies, and whether their use of these strategies had differed by partner type and couples’ HIV-status. The sample used a variety of risk-reduction strategies for UAI. Some differences and patterns by partner type and couples’ HIV status were detected about men’s use of these strategies. Findings indicate the need to bolster HIV prevention and education with gay male couples about their use of these strategies within and outside of their relationships. PMID:23247364

  1. Research Review: Psychosocial adjustment and mental health in former child soldiers – a systematic review of the literature and recommendations for future research (United States)

    Betancourt, Theresa S.; Borisova, Ivelina; Williams, Timothy P.; Meyers-Ohki, Sarah E.; Rubin-Smith, Julia E.; Annan, Jeannie; Kohrt, Brandon A.


    Aims and scope This article reviews the available quantitative research on psychosocial adjustment and mental health among children (age adjustment and social reintegration in CAAFAG. Abduction, age of conscription, exposure to violence, gender, and community stigma were associated with increased internalizing and externalizing mental health problems. Family acceptance, social support, and educational/economic opportunities were associated with improved psychosocial adjustment. Conclusions Research on the social reintegration and psychosocial adjustment of former child soldiers is nascent. A number of gaps in the available literature warrant future study. Recommendations to bolster the evidence base on psychosocial adjustment in former child soldiers and other war-affected youth include more studies comprising longitudinal study designs, and validated cross-cultural instruments for assessing mental health, as well as more integrated community-based approaches to study design and research monitoring. PMID:23061830

  2. From Awareness to Cultural Agency: EFL Colombian Student Teachers’ Travelling Abroad Experiences

    Directory of Open Access Journals (Sweden)

    John Jairo Viafara González


    Full Text Available Colombian English as a foreign language student teachers’ opportunities to grow as educators through international sojourns do not usually subsume the traditional study and residence abroad goal. This was the case for our participants who engaged mainly in working abroad with study being ancillary. Fifty student teachers from two public universities reported how their international sojourn bolstered their intercultural learning. Three different programs, disconnected from participants’ academic institutions, became vehicles for their experiences abroad. Surveys and interviews reveal that participants’ origin, selected programs, and contextual circumstances influenced their intercultural learning. As a result, intercultural development gravitated towards awareness of intercultural patterns, critical reading of culture, and pre-service teachers’ repositioning to build cultural agency. Implications suggest the need to connect traveling abroad programs to undergraduate curricula.

  3. Commodifying Indigeneity: How the Humanization of Birth Reinforces Racialized Inequality in Mexico. (United States)

    Vega, Rosalynn Adeline


    This article examines the humanized birth movement in Mexico and analyzes how the remaking of tradition-the return to traditional birthing arts (home birth, midwife-assisted birth, natural birth)-inadvertently reinscribes racial hierarchies. The great irony of the humanized birth movement lies in parents' perspective of themselves as critics of late capitalism. All the while, their very rejection of consumerism bolsters ongoing commodification of indigenous culture and collapses indigeneity, nature, and tradition onto one another. While the movement is quickly spreading across Mexico, indigenous women and their traditional midwives are largely excluded from the emerging humanized birth community. Through ethnographic examples, the article suggests that indigenous individuals are agentive actors who appropriate cards in decks stacked against them. Examples of resistance emerge within a context of power and political economy that often capitalizes on images of indigeneity while obscuring the lives, experiences, and opinions of indigenous people. © 2016 by the American Anthropological Association.

  4. The exceptional sediment load of fine-grained dispersal systems: Example of the Yellow River, China. (United States)

    Ma, Hongbo; Nittrouer, Jeffrey A; Naito, Kensuke; Fu, Xudong; Zhang, Yuanfeng; Moodie, Andrew J; Wang, Yuanjian; Wu, Baosheng; Parker, Gary


    Sedimentary dispersal systems with fine-grained beds are common, yet the physics of sediment movement within them remains poorly constrained. We analyze sediment transport data for the best-documented, fine-grained river worldwide, the Huanghe (Yellow River) of China, where sediment flux is underpredicted by an order of magnitude according to well-accepted sediment transport relations. Our theoretical framework, bolstered by field observations, demonstrates that the Huanghe tends toward upper-stage plane bed, yielding minimal form drag, thus markedly enhancing sediment transport efficiency. We present a sediment transport formulation applicable to all river systems with silt to coarse-sand beds. This formulation demonstrates a remarkably sensitive dependence on grain size within a certain narrow range and therefore has special relevance to silt-sand fluvial systems, particularly those affected by dams.

  5. Stabilization of switched nonlinear systems with unstable modes

    CERN Document Server

    Yang, Hao; Cocquempot, Vincent


    This book provides its reader with a good understanding of the stabilization of switched nonlinear systems (SNS), systems that are of practical use in diverse situations: design of fault-tolerant systems in space- and aircraft; traffic control; and heat propagation control of semiconductor power chips. The practical background is emphasized throughout the book; interesting practical examples frequently illustrate the theoretical results with aircraft and spacecraft given particular prominence. Stabilization of Switched Nonlinear Systems with Unstable Modes treats several different subclasses of SNS according to the characteristics of the individual system (time-varying and distributed parameters, for example), the state composition of individual modes and the degree and distribution of instability in its various modes. Achievement and maintenance of stability across the system as a whole is bolstered by trading off between individual modes which may be either stable or unstable, or by exploiting areas of part...

  6. "To Bluff like a Man or Fold like a Girl?" - Gender Biased Deceptive Behavior in Online Poker.

    Directory of Open Access Journals (Sweden)

    Jussi Palomäki

    Full Text Available Evolutionary psychology suggests that men are more likely than women to deceive to bolster their status and influence. Also gender perception influences deceptive behavior, which is linked to pervasive gender stereotypes: women are typically viewed as weaker and more gullible than men. We assessed bluffing in an online experiment (N = 502, where participants made decisions to bluff or not in simulated poker tasks against opponents represented by avatars. Participants bluffed on average 6% more frequently at poker tables with female-only avatars than at tables with male-only or gender mixed avatars-a highly significant effect in games involving repeated decisions. Nonetheless, participants did not believe the avatar genders affected their decisions. Males bluffed 13% more frequently than females. Unlike most economic games employed exclusively in research contexts, online poker is played for money by tens of millions of people worldwide. Thus, gender effects in bluffing have significant monetary consequences for poker players.

  7. "To Bluff like a Man or Fold like a Girl?" - Gender Biased Deceptive Behavior in Online Poker. (United States)

    Palomäki, Jussi; Yan, Jeff; Modic, David; Laakasuo, Michael


    Evolutionary psychology suggests that men are more likely than women to deceive to bolster their status and influence. Also gender perception influences deceptive behavior, which is linked to pervasive gender stereotypes: women are typically viewed as weaker and more gullible than men. We assessed bluffing in an online experiment (N = 502), where participants made decisions to bluff or not in simulated poker tasks against opponents represented by avatars. Participants bluffed on average 6% more frequently at poker tables with female-only avatars than at tables with male-only or gender mixed avatars-a highly significant effect in games involving repeated decisions. Nonetheless, participants did not believe the avatar genders affected their decisions. Males bluffed 13% more frequently than females. Unlike most economic games employed exclusively in research contexts, online poker is played for money by tens of millions of people worldwide. Thus, gender effects in bluffing have significant monetary consequences for poker players.

  8. Managing CSR Globally and Locally

    DEFF Research Database (Denmark)

    L. Brown, Dana; Knudsen, Jette Steen

    Corporate Responsibility (CR) is today an essential component of corporate global strategy. CR can bolster the institutional context for market expansion (Porter and Kramer 2006); fill institutional voids (Tarun, 2005); or facilitate market entry as a component of non-market strategy (Baron...... 2006). Yet, in fulfilling these functions, CR may need to be highly sensitive to local contexts. How can transnational firms organize CR so as to maximize efficiencies from globalization and to minimize the fragmentation of corporate organizational cultures? Bartlett and Ghoshal (1989) provide...... a framework for analyzing the way that corporations coordinate global and local functions. We build on this framework in a case study of Novo Nordisk and its approach to determining global and local CR policies and procedures with regard to its China and United States subsidiaries. Our findings suggest...

  9. Clean Energy Manufacturing: U.S. Competitiveness and State Policy Strategies (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Lantz, E.


    The capital intensive nature of clean energy technologies suggests that manufacturing clean energy equipment has the potential to support state and local economic development efforts. However, manufacturing siting decisions tend to be complex and multi-variable decision processes that require in-depth knowledge of specific markets, the logistical requirements of a given technology, and insight into global clean tech trends. This presentation highlights the potential of manufacturing in supporting economic development opportunities while also providing examples of the financial considerations affecting manufacturing facility siting decisions for wind turbine blades and solar PV. The presentation also includes discussion of other more qualitative drivers of facility siting decisions as gleaned from NREL industry interviews and discusses strategies state and local policymakers may employee to bolster their chances of successfully attracting clean energy manufacturers to their localities.


    Directory of Open Access Journals (Sweden)

    Максим Викторович Оськин


    Full Text Available This article considers the problem of food supply to the Eastern front in the winter of 1917 during World War I. In the conditions of the food supply crisis the military authorities managed to avoid the famine in the army. The Front Command and the Supreme Command took some measures to resolve this problem. Attracting extra workers for harvesting, clarity of the resources allocation, calculations of the government funds allocation- all these actions bolstered the army's efforts on the home front. A considerable role in this work was played by Emperor Nicholas II, who timely and positively reacted to the suggestions of the military commanders on the issue. Overall, the Russian military command coped with this problem in the conditions of the general crisis of supplies.

  11. The Effects of Stigma on Recovery Attitudes in People With Anorexia Nervosa in Intensive Treatment. (United States)

    Dimitropoulos, Gina; McCallum, Leslie; Colasanto, Marlena; Freeman, Victoria E; Gadalla, Tahany


    Self-stigma in individuals with anorexia nervosa (AN) may affect engagement in intensive treatment. The objective of this study was to test a Model of Self-Stigma to identify the influence of public stigma, internalized stigma, self-esteem, and self-efficacy on recovery attitudes in individuals in inpatient treatment for AN. Using a cross-sectional design, 36 female participants with AN completed questionnaires during the first week of intensive inpatient treatment. Better attitude towards recovery was positively correlated with higher self-esteem and self-efficacy and negatively correlated with greater internalized stigma and perceptions of others devaluing families of individuals with AN. Together, these factors accounted for 63% of the variance in recovery attitudes. Findings demonstrate the adverse effects perceived stigma towards families, self-stigma, and self-esteem have on recovery attitudes in individuals with AN. Clinical interventions are needed to challenge internalized stigma and bolster self-esteem to enhance individuals' recovery efforts.

  12. [Sialic Acid Replacement Therapy for Distal Myopathy with Rimmed Vacuoles]. (United States)

    Mori-Yoshimura, Madoka; Nishino, Ichizo


    Distal myopathy with rimmed vacuoles or GNE myopathy, is an early adult-onset myopathy with slow progression that preferentially affects the tibialis anterior muscle. Severely affected patients show marked limb muscle atrophy together with respiratory dysfunction. The disease is caused by a mutation in the GNE gene that catalyzes two rate-limiting reactions in cytosolic sialic acid synthesis. Oral treatment with sialic acid metabolite prevents muscle atrophy and weakness in a mouse GNE myopathy model and a global Phase III study is currently underway. In addition, a global patient registry of neuromuscular cases is widely accepted as a useful tool to obtain epidemiological data and bolster patient recruitment for further development of this treatment strategy.

  13. Shifting Liberal and Conservative Attitudes Using Moral Foundations Theory (United States)

    Day, Martin V.; Fiske, Susan T.; Downing, Emily L.; Trail, Thomas E.


    People’s social and political opinions are grounded in their moral concerns about right and wrong. We examine whether five moral foundations—harm, fairness, ingroup, authority, and purity—can influence political attitudes of liberals and conservatives across a variety of issues. Framing issues using moral foundations may change political attitudes in at least two possible ways: 1. Entrenching: relevant moral foundations will strengthen existing political attitudes when framing pro-attitudinal issues (e.g., conservatives exposed to a free-market economic stance). 2. Persuasion: mere presence of relevant moral foundations may also alter political attitudes in counter-attitudinal directions (e.g., conservatives exposed to an economic regulation stance). Studies 1 and 2 support the entrenching hypothesis. Relevant moral foundation-based frames bolstered political attitudes for conservatives (Study 1) and liberals (Study 2). Only Study 2 partially supports the persuasion hypothesis. Conservative-relevant moral frames of liberal issues increased conservatives’ liberal attitudes. PMID:25286912

  14. Transformation of a City

    Directory of Open Access Journals (Sweden)

    Trenessa L. Williams


    Full Text Available Gentrification changes the landscape and the cultural makeup of a city by increasing property values and changing consumption patterns. Since the late 1980s, gentrification has challenged the residential and small business community of Harlem, New York. Guided by the rent gap theory and the consumption-side theory, the purpose of this case study was to explore how small business leaders can compete with demographical changes brought by gentrification. A purposive sample of 20 Harlem small business owners operating during the city’s gentrification participated in interviews. Interview interpretations were triangulated with government documents and periodicals to bolster the trustworthiness of the final report. These findings may contribute to positive social change by informing the strategies employed by small business owners who are currently facing gentrification.

  15. Paradigm Shift: Report on the New Role of Design in Business and Society

    Directory of Open Access Journals (Sweden)

    Gjoko Muratovski

    Full Text Available Corporate cultures' prevailing attitudes towards design have begun to shift. Financial companies and management consultancies now have design teams, and include “design” in their service portfolios. Large corporations are bolstering their in-house design capabilities, and appointing designers to executive roles. Venture capitalist firms and startups increasingly recognize the value of including designers in the early stages of business development. Even global organizations and international foundations now list design on their agendas. A paradigm shift is taking place in the field of design. This study examines some of the latest corporate investments in design, and reflects on what this phenomenon means for the wider field of design. The focus of this study is on the key trend indicators that are defining the current landscape of design, and its changing role in business and society.

  16. Understanding TGEV-ETEC Coinfection through the Lens of Proteomics: A Tale of Porcine Diarrhea. (United States)

    Arango Duque, Guillermo; Acevedo Ospina, Hamlet Adolfo


    Porcine diarrhea and gastroenteritis are major causes of piglet mortality that result in devastating economic losses to the industry. A plethora of pathogens can cause these diseases, with the transmissible gastroenteritis virus (TGEV) and enterotoxigenic Escherichia coli K88 (ETEC) being two of the most salient. In the December 2017 issue of Proteomics Clinical Aplications, Xia and colleagues used comparative proteomics to shed light on how these microbes interact to cause severe disease . The authors discovered that TGEV induces an epithelial-mesenchymal transition-like phenotype that augments cell adhesion proteins mediating the attachment of ETEC to intestinal epithelial cells. Moreover, coinfection was found to modulate several host proteins that could bolster pathogen persistence. Importantly, the authors observed that ETEC suppresses the production of inflammatory cytokines induced by TGEV, which may in turn promote the long-term survival of both microbes. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria?

    Directory of Open Access Journals (Sweden)

    Janet Hemingway


    Full Text Available Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and prevent malaria, including innovative diagnostics, medicines, vaccines, vector control products, and improved mechanisms for surveillance and response. There are at least 25 projects in the global malaria vaccine pipeline, as well as 47 medicines and 13 vector control products. In addition, there are several next-generation diagnostic tools and reference methods currently in development, with many expected to be introduced in the next decade. The development and adoption of these tools, bolstered by strategies that ensure rapid uptake in target populations, intensified mechanisms for information management, surveillance, and response, and continued financial and political commitment are all essential to achieving global eradication.

  18. Information Literacy on the Web: How College Students Use Visual and Textual Cues to Assess Credibility on Health Websites

    Directory of Open Access Journals (Sweden)

    Katrina L. Pariera


    Full Text Available One of the most important literacy skills in today’s information society is the ability to determine the credibility of online information. Users sort through a staggering number of websites while discerning which will provide satisfactory information. In this study, 70 college students assessed the credibility of health websites with a low and high design quality, in either low or high credibility groups. The study’s purpose was to understand if students relied more on textual or visual cues in determining credibility, and to understand if this affected their recall of those cues later. The results indicate that when viewing a high credibility website, high design quality will bolster the credibility perception, but design quality will not compensate for a low credibility website. The recall test also indicated that credibility does impact the participants’ recall of visual and textual cues. Implications are discussed in light of the Elaboration Likelihood Model.

  19. Learning by Doing

    DEFF Research Database (Denmark)

    Liu, Fei; Xiao, Bo Sophia; Lim, Eric T. K.


    Information search is becoming increasingly demanding due to the booming of Consumer Generated Content (CGC) in online environment. This has led to growing scholarly interest in designing search features to accommodate diverse user preferences. Drawing on the Theory of Affordance Informativity, we...... advance ostensive informativity and performative informativity as focal mechanisms for search features to convey actions afforded to users. We further put forth a typology of search features that is grounded in both dimensions of search affordance informativities. Next, we construct a research framework...... that depicts how search affordance informativity bolsters information search performance. By conducting a field experiment on our custom-made online restaurant review website, we discovered that performative informativity increases search result anticipation and reduces search costs whereas ostensive...

  20. Structure of the T6SS lipoprotein TssJ1 from Pseudomonas aeruginosa

    International Nuclear Information System (INIS)

    Robb, Craig S.; Assmus, Mark; Nano, Francis E.; Boraston, Alisdair B.


    The crystal structure of the type VI secretion-system protein TssJ1 from P. aeruginosa was solved by iodide SAD at a resolution of 1.4 Å. The type VI secretion system of Pseudomonas aeruginosa has been shown to be responsible for the translocation of bacteriolytic effectors into competing bacteria. A mechanistic understanding of this widely distributed secretion system is developing and structural studies of its components are ongoing. Two representative structures of one highly conserved component, TssJ, from Escherichia coli and Serratia marcescens have been published. Here, the X-ray crystal structure of TssJ1 from P. aeruginosa is presented at 1.4 Å resolution. The overall structure is conserved among the three proteins. This finding suggests that the homologues function in a similar manner and bolsters the understanding of the structure of this family of proteins

  1. Conformational analysis of small organic molecules using NOE and RDC data: A discussion of strychnine and α-methylene-γ-butyrolactone (United States)

    Kolmer, Andreas; Edwards, Luke J.; Kuprov, Ilya; Thiele, Christina M.


    To understand the properties and/or reactivity of an organic molecule, an understanding of its three-dimensional structure is necessary. Simultaneous determination of configuration and conformation often poses a daunting challenge. Thus, the more information accessible for a given molecule, the better. Additionally to 3J-couplings, two sources of information, quantitative NOE and more recently also RDCs, are used for conformational analysis by NMR spectroscopy. In this paper, we compare these sources of conformational information in two molecules: the configurationally well-characterized strychnine 1, and the only recently configurationally and conformationally characterized α -methylene- γ -butyrolactone 2. We discuss possible sources of error in the measurement and analysis process, and how to exclude them. By this means, we are able to bolster the previously proposed flexibility for these two molecules.

  2. Partial Nephrectomy in a Patient with a Left Ventricular Assist Device

    Directory of Open Access Journals (Sweden)

    Jules P. Manger


    Full Text Available Left ventricular assist device (LVAD use has increased as a bridge to heart transplant as well as destination therapy in patients with severe heart failure. Presence of LVAD is not a contraindication to noncardiac surgery but does present special challenges to the surgical, anesthesia, and cardiac teams. We present the case of a 40-year-old woman with idiopathic cardiomyopathy necessitating LVAD who underwent left partial nephrectomy for a renal mass. She had undergone three nondiagnostic percutaneous image-guided biopsies. Left partial nephrectomy was performed. Perioperative care was without incident due to careful oversight by a multidisciplinary team. Pathology revealed high-grade clear cell renal cell carcinoma (RCC with negative margins. Polytetrafluoroethylene (PTFE bolsters were misidentified six months postoperatively on computed tomography (CT at an outside institution as a retained laparotomy sponge. This is, to our knowledge, the first report of a partial nephrectomy performed in a patient with LVAD.

  3. NAD+ in Aging

    DEFF Research Database (Denmark)

    Fang, Evandro F.; Lautrup, Sofie; Hou, Yujun


    neuronal function. NAD+ depletion is detected in major neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, cardiovascular disease and muscle atrophy. Emerging evidence suggests that NAD+ decrements occur in various tissues during aging, and that physiological and pharmacological...... interventions bolstering cellular NAD+ levels might retard aspects of aging and forestall some age-related diseases. Here, we discuss aspects of NAD+ biosynthesis, together with putative mechanisms of NAD+ action against aging, including recent preclinical and clinical trials. Recent discoveries have...... DNA repair and mitochondrial maintenance. Mitochondrial autophagy (mitophagy) has a major role in clearance of damaged and/or dysfunctional mitochondria, and compromised mitophagy has been linked to metabolic disorders, neurodegeneration [including Alzheimer's disease (AD) and Parkinson's disease (PD...

  4. Mediators of adherence among adults with comorbid diabetes and depression: The role of self-efficacy and social support. (United States)

    Tovar, Elizabeth; Rayens, Mary Kay; Gokun, Yevgeniya; Clark, Michele


    Depression and diabetes have been linked in a variety of ways, and the presence of depression in those with diabetes can negatively affect adherence to care recommendations. A sample of 201 participants with Type 2 Diabetes completed a cross-sectional survey that assessed depressive symptoms, adherence, self-efficacy, social support, and personal characteristics. Multiple regression analysis was used to test whether self-efficacy and social support mediate the relationship between depressive symptoms and adherence. The findings suggest complete mediation via self-efficacy and some types of social support. Intervening to bolster self-efficacy and social support may decrease the negative effect of depression on adherence. © The Author(s) 2013.

  5. Engineering alcohol tolerance in yeast (United States)

    Lam, Felix H.; Ghaderi, Adel; Fink, Gerald R.; Stephanopoulos, Gregory


    Ethanol toxicity in yeast Saccharomyces cerevisiae limits titer and productivity in the industrial production of transportation bioethanol. We show that strengthening the opposing potassium and proton electrochemical membrane gradients is a mechanism that enhances general resistance to multiple alcohols. Elevation of extracellular potassium and pH physically bolster these gradients, increasing tolerance to higher alcohols and ethanol fermentation in commercial and laboratory strains (including a xylose-fermenting strain) under industrial-like conditions. Production per cell remains largely unchanged with improvements deriving from heightened population viability. Likewise, up-regulation of the potassium and proton pumps in the laboratory strain enhances performance to levels exceeding industrial strains. Although genetically complex, alcohol tolerance can thus be dominated by a single cellular process, one controlled by a major physicochemical component but amenable to biological augmentation. PMID:25278607

  6. Biofuels. Engineering alcohol tolerance in yeast. (United States)

    Lam, Felix H; Ghaderi, Adel; Fink, Gerald R; Stephanopoulos, Gregory


    Ethanol toxicity in the yeast Saccharomyces cerevisiae limits titer and productivity in the industrial production of transportation bioethanol. We show that strengthening the opposing potassium and proton electrochemical membrane gradients is a mechanism that enhances general resistance to multiple alcohols. The elevation of extracellular potassium and pH physically bolsters these gradients, increasing tolerance to higher alcohols and ethanol fermentation in commercial and laboratory strains (including a xylose-fermenting strain) under industrial-like conditions. Production per cell remains largely unchanged, with improvements deriving from heightened population viability. Likewise, up-regulation of the potassium and proton pumps in the laboratory strain enhances performance to levels exceeding those of industrial strains. Although genetically complex, alcohol tolerance can thus be dominated by a single cellular process, one controlled by a major physicochemical component but amenable to biological augmentation. Copyright © 2014, American Association for the Advancement of Science.

  7. Housing as a Social Determinant of Health: Exploring the Relationship between Rent Burden and Risk Behaviors for Single Room Occupancy Building Residents. (United States)

    Bowen, Elizabeth A; Mitchell, Christopher G


    A growing body of health determinants research recognizes that housing and health are intimately linked. This study explores the relationship between rent burden (the ratio of rent to income) and health risk behaviors among a sample of single room occupancy (SRO) building residents. Cross-sectional data were gathered from a sample of 162 residents living in privately owned, for-profit SROs in Chicago. Findings indicated that participants who had full rental subsidies and thus were designated in a no-rent-burden category were more likely to engage in risk behaviors including illicit drug use, having multiple sexual partners, and having sex without a condom, in comparison to participants with moderate or high-rent burdens. These findings suggest that interventions to increase housing stability and affordability and bolster reliable income sources (in addition to rental subsidies) may be key in reducing risk behaviors and improving health for vulnerably housed populations such as SRO residents.

  8. The Interaction of Language-Specific and Universal Factors During the Acquisition of Morphophonemic Alternations With Exceptions. (United States)

    Baer-Henney, Dinah; Kügler, Frank; van de Vijver, Ruben


    Using the artificial language paradigm, we studied the acquisition of morphophonemic alternations with exceptions by 160 German adult learners. We tested the acquisition of two types of alternations in two regularity conditions while additionally varying length of training. In the first alternation, a vowel harmony, backness of the stem vowel determines backness of the suffix. This process is grounded in substance (phonetic motivation), and this universal phonetic factor bolsters learning a generalization. In the second alternation, tenseness of the stem vowel determines backness of the suffix vowel. This process is not based in substance, but it reflects a phonotactic property of German and our participants benefit from this language-specific factor. We found that learners use both cues, while substantive bias surfaces mainly in the most unstable situation. We show that language-specific and universal factors interact in learning. Copyright © 2014 Cognitive Science Society, Inc.

  9. Linking population, fertility, and family planning with adaptation to climate change: perspectives from Ethiopia. (United States)

    Rovin, Kimberly; Hardee, Karen; Kidanu, Aklilu


    Global climate change is felt disproportionately in the world's most economically disadvantaged countries. As adaption to an evolving climate becomes increasingly salient on national and global scales, it is important to assess how people at the local-level are already coping with changes. Understanding local responses to climate change is essential for helping countries to construct strategies to bolster resilience to current and future effects. This qualitative research investigated responses to climate change in Ethiopia; specifically, how communities react to and cope with climate variation, which groups are most vulnerable, and the role of family planning in increasing resilience. Participants were highly aware of changing climate effects, impacts of rapid population growth, and the need for increased access to voluntary family planning. Identification of family planning as an important adaptation strategy supports the inclusion of rights-based voluntary family planning and reproductive health into local and national climate change adaptation plans.

  10. Social Stigma and Sexual Minorities' Romantic Relationship Functioning: A Meta-Analytic Review. (United States)

    Doyle, David Matthew; Molix, Lisa


    To bolster knowledge of determinants of relationship functioning among sexual minorities, the current meta-analysis aimed to quantitatively review evidence for the association between social stigma and relationship functioning as well as examine potential moderators. Thirty-five studies were identified, including 130 effect sizes (39 independent; N = 10,745). Across studies, evidence was found for a small but significant inverse association between social stigma and relationship functioning. Furthermore, this association was moderated by stigma type (with more deleterious associations for internalized relative to perceived stigma) and dimension of relationship functioning (with more deleterious associations for affective relative to cognitive and negative relative to positive). Evidence for demographic moderators (region, sex, race, age) was generally mixed although important limitations related to unique characteristics of study samples are discussed. We conclude by highlighting the importance of social stigma for relationship functioning and point toward directions for future research and policy action. © 2015 by the Society for Personality and Social Psychology, Inc.

  11. Social Stigma and Sexual Minorities’ Romantic Relationship Functioning: A Meta-Analytic Review (United States)

    Doyle, David Matthew; Molix, Lisa


    To bolster knowledge of determinants of relationship functioning among sexual minorities, the current meta-analysis aimed to quantitatively review evidence for the association between social stigma and relationship functioning as well as examine potential moderators. Thirty-five studies were identified, including 130 effect sizes (39 independent; N = 10,745). Across studies, evidence was found for a small but significant inverse association between social stigma and relationship functioning. Furthermore, this association was moderated by stigma type (with more deleterious associations for internalized relative to perceived stigma) and dimension of relationship functioning (with more deleterious associations for affective relative to cognitive and negative relative to positive). Evidence for demographic moderators (region, sex, race, age) was generally mixed although important limitations related to unique characteristics of study samples are discussed. We conclude by highlighting the importance of social stigma for relationship functioning and point toward directions for future research and policy action. PMID:26199218

  12. [Health education in schools in Argentina: an art contest as a motivating activity]. (United States)

    Darnaud, Raquel; Dato, María Isabel


    The purpose of this study was to plan health education efforts that integrate the health and education sectors. From March to November 2004, an art contest was held for 7th-9th grade students in 109 schools in 11 of Argentina's provinces. The contest allowed improvements in knowledge to be measured and adjustments to be made to the curriculum. The students created works of art featuring tuberculosis. To evaluate knowledge acquired, two provinces were chosen at random. Student knowledge had increased from 67.2% to 96.4%. The administrators and teachers testified to the usefulness of the materials developed. These results show that when the efforts of health and education sectors are coordinated and the appropriate materials are leveraged, the efforts of educators can be substantially bolstered.

  13. Sources and dispersive modes of micro-fibers in the environment. (United States)

    Carr, Steve A


    Understanding the sources and distribution of microfibers (MFs) in the environment is critical if control and remediation measures are to be effective. Microfibers comprise an overwhelming fraction (>85%) of microplastic debris found on shorelines around the world. Although primary sources have not been fully vetted, until recently it was widely believed that domestic laundry discharges were the major source. It was also thought that synthetic fibers and particles having dimensions environment. This finding may bolster concerns that active and pervasive shedding of fibers from common fabrics and textiles could be contributing significantly, via direct pathways, to burgeoning environmental loads. Integr Environ Assess Manag 2017;13:466-469. © 2017 SETAC. © 2017 SETAC.

  14. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Tucker, Jo A.; Jochems, Caroline [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Gulley, James L. [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Schlom, Jeffrey, E-mail:; Tsang, Kwong Y. [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States)


    Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies.

  15. Climate warming drives local extinction: Evidence from observation and experimentation. (United States)

    Panetta, Anne Marie; Stanton, Maureen L; Harte, John


    Despite increasing concern about elevated extinction risk as global temperatures rise, it is difficult to confirm causal links between climate change and extinction. By coupling 25 years of in situ climate manipulation with experimental seed introductions and both historical and current plant surveys, we identify causal, mechanistic links between climate change and the local extinction of a widespread mountain plant ( Androsace septentrionalis ). Climate warming causes precipitous declines in population size by reducing fecundity and survival across multiple life stages. Climate warming also purges belowground seed banks, limiting the potential for the future recovery of at-risk populations under ameliorated conditions. Bolstered by previous reports of plant community shifts in this experiment and in other habitats, our findings not only support the hypothesis that climate change can drive local extinction but also foreshadow potentially widespread species losses in subalpine meadows as climate warming continues.

  16. Clarifying the link between childhood abuse history and psychopathic traits in adult criminal offenders (United States)

    Dargis, Monika; Newman, Joseph; Koenigs, Michael


    Childhood abuse is a risk factor for the development of externalizing characteristics and disorders, including antisocial personality disorder and psychopathy. However, the precise relationships between particular types of childhood maltreatment and subsequent antisocial and psychopathic traits remain unclear. Using a large sample of incarcerated adult male criminal offenders (n = 183), the current study confirmed that severity of overall childhood maltreatment was linked to severity of both psychopathy and antisocial personality disorder in adulthood. Moreover, this relationship was particularly strong for physical abuse and the antisocial facet of psychopathy. Sexual abuse history was uniquely related to juvenile conduct disorder severity, rather than adult psychopathy or antisocial behaviors. Additionally, there was a significantly stronger relationship between childhood maltreatment and juvenile conduct disorder than between childhood maltreatment and ASPD or psychopathy. These findings bolster and clarify the link between childhood maltreatment and antisocial behavior later in life. PMID:26389621

  17. The Characterization of Biosignatures in Caves Using an Instrument Suite (United States)

    Uckert, Kyle; Chanover, Nancy J.; Getty, Stephanie; Voelz, David G.; Brinckerhoff, William B.; McMillan, Nancy; Xiao, Xifeng; Boston, Penelope J.; Li, Xiang; McAdam, Amy; Glenar, David A.; Chavez, Arriana


    The search for life and habitable environments on other Solar System bodies is a major motivator for planetary exploration. Due to the difficulty and significance of detecting extant or extinct extraterrestrial life in situ, several independent measurements from multiple instrument techniques will bolster the community's confidence in making any such claim. We demonstrate the detection of subsurface biosignatures using a suite of instrument techniques including IR reflectance spectroscopy, laser-induced breakdown spectroscopy, and scanning electron microscopy/energy dispersive X-ray spectroscopy. We focus our measurements on subterranean calcium carbonate field samples, whose biosignatures are analogous to those that might be expected on some high-interest astrobiology targets. In this work, we discuss the feasibility and advantages of using each of the aforementioned instrument techniques for the in situ search for biosignatures and present results on the autonomous characterization of biosignatures using multivariate statistical analysis techniques.

  18. Application and Utility of Psychodynamic Principles in Forensic Assessment. (United States)

    Simopoulos, Eugene F; Cohen, Bruce


    Effective practice of forensic psychiatry is dependent on a clinical recognition and understanding of core psychodynamic principles and theory. Practice guidelines, rooted in the ethics-based imperative to strive for honesty and objectivity, demand that practitioners remain vigilant to the development of bias and appreciate interpersonal dynamics that may be re-enacted in the forensic setting. Although it is not feasible to maintain complete impartiality, especially when confronted with the nature of certain offenses, knowledge of both conscious and unconscious responses can bolster the intellectual integrity of the clinical assessment. The identification of defense mechanisms within both the evaluator and evaluee and attention to transference and countertransference are essential for an accurate conceptualization of an offender's psychological functioning, vulnerabilities, and risk of reoffense. In this article, we review psychodynamic concepts and their potential impact in the forensic setting and underscore interventions that may aid in the elucidation and management of these processes. © 2015 American Academy of Psychiatry and the Law.

  19. Brain insulin signaling and Alzheimer's disease: current evidence and future directions. (United States)

    Schiöth, Helgi B; Craft, Suzanne; Brooks, Samantha J; Frey, William H; Benedict, Christian


    Insulin receptors in the brain are found in high densities in the hippocampus, a region that is fundamentally involved in the acquisition, consolidation, and recollection of new information. Using the intranasal method, which effectively bypasses the blood-brain barrier to deliver and target insulin directly from the nose to the brain, a series of experiments involving healthy humans has shown that increased central nervous system (CNS) insulin action enhances learning and memory processes associated with the hippocampus. Since Alzheimer's disease (AD) is linked to CNS insulin resistance, decreased expression of insulin and insulin receptor genes and attenuated permeation of blood-borne insulin across the blood-brain barrier, impaired brain insulin signaling could partially account for the cognitive deficits associated with this disease. Considering that insulin mitigates hippocampal synapse vulnerability to amyloid beta and inhibits the phosphorylation of tau, pharmacological strategies bolstering brain insulin signaling, such as intranasal insulin, could have significant therapeutic potential to deter AD pathogenesis.

  20. Managing Corporate Responsibility Globally and Locally

    DEFF Research Database (Denmark)

    Brown, Dana; Knudsen, Jette Steen


    Corporate Responsibility (CR) is today an essential component of corporate global strategy. CR can bolster the institutional context for market expansion fill institutional voids or facilitate market entry as a component of non-market strategy. Yet, in fulfilling these functions, CR may need...... to be highly sensitive to local contexts. How can transnational firms organize CR so as to maximize efficiencies from globalization and to minimize the fragmentation of corporate organizational cultures? provide a framework for analyzing the way that corporations coordinate global and local functions. We build...... on this framework in a case study of Novo Nordisk and its approach to determining global and local CR policies and procedures with regard to its China and US subsidiaries. Our findings suggest that it is important for companies to define a common set of organizational norms. In addition, CR need to be sensitive...

  1. Passing Down the Experience

    DEFF Research Database (Denmark)

    Liu, Fei; Lim, Eric T. K.; Tan, Chee-Wee


    Consumers are growing increasingly dependent on Online Customer Reviews (OCRs) when making consumption decisions, more so for services due to their intangibility and variability. To this end, we advance a research model that explores how numerical ratings and opinionated reviews, as key constitue......Consumers are growing increasingly dependent on Online Customer Reviews (OCRs) when making consumption decisions, more so for services due to their intangibility and variability. To this end, we advance a research model that explores how numerical ratings and opinionated reviews, as key...... research model was subsequently validated via a field study that was conducted on a custom developed online restaurant review site. Results suggest that numerical rating and opinionated review can amplify the effectiveness and efficiency of consumers’ decision making process by bolstering the latter...

  2. Educación para la salud en escuelas argentinas: concurso de plástica como actividad motivadora Health education in schools in Argentina: an art contest as a motivating activity

    Directory of Open Access Journals (Sweden)

    Raquel Darnaudy


    Full Text Available The purpose of this study was to plan health education efforts that integrate the health and education sectors. From March to November 2004, an art contest was held for 7th-9th grade students in 109 schools in 11 of Argentina's provinces. The contest allowed improvements in knowledge to be measured and adjustments to be made to the curriculum. The students created works of art featuring tuberculosis. To evaluate knowledge acquired, two provinces were chosen at random. Student knowledge had increased from 67.2% to 96.4%. The administrators and teachers testified to the usefulness of the materials developed. These results show that when the efforts of health and education sectors are coordinated and the ap propriate materials are leveraged, the efforts of educators can be substantially bolstered.

  3. The past makes the present meaningful: nostalgia as an existential resource. (United States)

    Routledge, Clay; Arndt, Jamie; Wildschut, Tim; Sedikides, Constantine; Hart, Claire M; Juhl, Jacob; Vingerhoets, Ad J J M; Schlotz, Wolff


    The present research tested the proposition that nostalgia serves an existential function by bolstering a sense of meaning in life. Study 1 found that nostalgia was positively associated with a sense of meaning in life. Study 2 experimentally demonstrated that nostalgia increases a sense of meaning in life. In both studies, the link between nostalgia and increased meaning in life was mediated by feelings of social connectedness. Study 3 evidenced that threatened meaning increases nostalgia. Study 4 illustrated that nostalgia, in turn, reduces defensiveness following a meaning threat. Finally, Studies 5 and 6 showed that nostalgia disrupts the link between meaning deficits and compromised psychological well-being. Collectively, these findings indicate that the provision of existential meaning is a pivotal function of nostalgia. PsycINFO Database Record (c) 2011 APA, all rights reserved.

  4. Nostalgia: content, triggers, functions. (United States)

    Wildschut, Tim; Sedikides, Constantine; Arndt, Jamie; Routledge, Clay


    Seven methodologically diverse studies addressed 3 fundamental questions about nostalgia. Studies 1 and 2 examined the content of nostalgic experiences. Descriptions of nostalgic experiences typically featured the self as a protagonist in interactions with close others (e.g., friends) or in momentous events (e.g., weddings). Also, the descriptions contained more expressions of positive than negative affect and often depicted the redemption of negative life scenes by subsequent triumphs. Studies 3 and 4 examined triggers of nostalgia and revealed that nostalgia occurs in response to negative mood and the discrete affective state of loneliness. Studies 5, 6, and 7 investigated the functional utility of nostalgia and established that nostalgia bolsters social bonds, increases positive self-regard, and generates positive affect. These findings demarcate key landmarks in the hitherto uncharted research domain of nostalgia.

  5. Analysis of Various Computer System Monitoring and LCD Projector through the Network TCP/IP

    Directory of Open Access Journals (Sweden)

    Santoso Budijono


    Full Text Available Many electronic devices have a network connection facility. Projectors today have network facilities to bolster its customer satisfaction in everyday use. By using a device that can be controlled, the expected availability and reliability of the presentation system (computer and projector can be maintained to keep itscondition ready to use for presentation. Nevertheless, there is still a projector device that has no network facilities so that the necessary additional equipment with expensive price. Besides, control equipment in large quantities has problems in timing and the number of technicians in performing controls. This study began with study of literature, from searching for the projectors that has LAN and software to control and finding a number of computer control softwares where the focus is easy to use and affordable. Result of this research is creating asystem which contains suggestions of procurement of computer hardware, hardware and software projectors each of which can be controlled centrally from a distance.

  6. Elements of condom use decision-making among MSM in South Africa (United States)

    Siegler, Aaron J.; de Voux, Alex; Phaswana-Mafuya, Nancy; Bekker, Linda-Gail; Sullivan, Patrick S.; Baral, Stefan D.; Winskell, Kate; Kose, Zamakayise; Wirtz, Andrea L.; Stephenson, Rob


    South African men who have sex with men (MSM) are at increased risk for HIV infection, and male condoms are fundamental to HIV prevention programs. We explored condom use experiences through in-depth interviews with 34 MSM in Cape Town and Port Elizabeth, South Africa. For data analysis, we generated a codebook and used the constant comparison method. Condom use reinforcing elements included use of alternative sexual strategies, having a high level of self-worth that was linked to protective behaviors, and use of ready-made condom negotiation scripts. Elements inhibiting condom use included perceiving substantial declines in sexual pleasure/performance, experiences of condom failure (possibly related to petroleum-based lubricant), and being in trusted relationships. Our findings suggest nuanced HIV prevention approaches such as bolstering condom negotiation skills based on successful tactics already in use. Further research is needed to address how to mitigate perceptions and experiences that condoms negatively impact sexual pleasure and performance. PMID:24935692

  7. Nasoethmoid orbital fractures. Current concepts and management principles. (United States)

    Leipziger, L S; Manson, P N


    The proper management of nasoethmoid orbital fractures relies upon early accurate diagnosis and treatment. A surgical plan must be established after careful review of the physical examination and CT scans. Identification of the extent and type of fracture pattern determines the operative approach. Extended (wide) exposure, using craniofacial techniques, facilitates precise reduction and rigid fixation of all bone fragments. Transnasal reduction of the canthus-bearing central segment (medial orbital rim) is the critical operative maneuver required to achieve normal intercanthal distance. Immediate bone grafting replaces severely comminuted or missing bone fragments. The skin overlying the nasoethmoid area is carefully redraped by gentle pressure from padded external compression bolsters. These principles form the basis for superior aesthetic and functional results.

  8. Application of geographic information systems and asset mapping to facilitate identification of colorectal cancer screening resources. (United States)

    Gwede, Clement Kudzai; Ward, Beverly G; Luque, John S; Vadaparampil, Susan T; Rivers, Desiree; Martinez-Tyson, Dinorah; Noel-Thomas, Shalewa; Meade, Cathy D


    We sought to identify and map the geographic distribution of available colorectal cancer screening resources; following identification of this priority within a needs assessment of a local community-academic collaborative to reduce cancer health disparities in medically underserved communities. We used geographic information systems (GIS) and asset mapping tools to visually depict resources in the context of geography and a population of interest. We illustrate two examples, offer step-by-step directions for mapping, and discuss the challenges, lessons learned, and future directions for research and practice. Our positive asset driven, community-based approach illustrated the distribution of existing colonoscopy screening facilities and locations of populations and organizations who might use these resources. A need for additional affordable and accessible colonoscopy resources was identified. These transdisciplinary community mapping efforts highlight the benefit of innovative community-academic partnerships for addressing cancer health disparities by bolstering infrastructure and community capacity-building for increased access to colonoscopies.

  9. Tariff Integration for Public Transportation in the Metropolitan Area of Bucaramanga

    Directory of Open Access Journals (Sweden)

    José Carlos Jiménez Serpa


    Full Text Available The sole implementation of a Bus Rapid Transit System -BRT parallel to the conventional is not enough to guarantee meeting users and operators’ needs within the Metropolitan Area of Bucaramanga -MAB, Colombia. As time passed, these systems became inefficient; as a result, users started looking for alternative non-formal transportation means and the State incurred in additional financing for the permanence of the system. This paper seeks to bolster the modes of public transportation through a fare strategy that agrees with the actual distances travelled by the user. In other words, the purpose of this work is to establish tariff zones for the AMB to differentiate between those users moving in short journeys and those who travel long distances to get to their destination in order to create a balance between the users’ benefit, the quality of the travel, and the operation costs of BRT.

  10. Discrete Effects of Religiosity and Spirituality on Gay Identity and Self-Esteem. (United States)

    Stern, Suzanne; Wright, A Jordan


    Previous research has indicated that although spirituality may bolster development of a positive gay identity, religiosity may prove detrimental. Because the majority of this research confounds these constructs, there is little evidence as to the discrete roles religiosity and spirituality may play in LGB identity development. The present study endeavored to tease apart the unique effects of religion and spirituality on positive and negative gay identity and self-esteem. A sample of 376 self-identified sexual minority adults were given measures of religiosity, spirituality, LGB identity, and self-esteem. Models were built to evaluate the effects of religiosity (independent of spirituality) and spirituality (independent of religiosity), understanding that the constructs are greatly overlapped, on identity and self-esteem. Results included a positive association between spirituality and identity affirmation, identity superiority, and self-esteem. Religiosity was negatively associated with identity affirmation and self-esteem and positively associated with internalized homonegativity and heteronormativity. Limitations and implications are discussed.

  11. "Abomination"--life as a Bible belt gay. (United States)

    Barton, Bernadette


    Drawing on observation, autoethnography, and audio-taped interviews, this article explores the religious backgrounds and experiences of Bible Belt gays. In the Bible Belt, Christianity is not confined to Sunday worship. Christian crosses, messages, paraphernalia, music, news, and attitudes permeate everyday settings. Consequently, Christian fundamentalist dogma about homosexuality-that homosexuals are bad, diseased, perverse, sinful, other, and inferior-is cumulatively bolstered within a variety of other social institutions and environments in the Bible Belt. Of the 46 lesbians and gay men interviewed for this study (age 18-74 years), most describe living through spirit-crushing experiences of isolation, abuse, and self-loathing. This article argues that the geographic region of the Bible Belt intersects with religious-based homophobia. Informants explained that negative social attitudes about homosexuality caused a range of harmful consequences in their lives including the fear of going to hell, depression, low self-esteem, and feelings of worthlessness.

  12. The use of brain organoids to investigate neural development and disease. (United States)

    Di Lullo, Elizabeth; Kriegstein, Arnold R


    Understanding the development and dysfunction of the human brain is a major goal of neurobiology. Much of our current understanding of human brain development has been derived from the examination of post-mortem and pathological specimens, bolstered by observations of developing non-human primates and experimental studies focused largely on mouse models. However, these tissue specimens and model systems cannot fully capture the unique and dynamic features of human brain development. Recent advances in stem cell technologies that enable the generation of human brain organoids from pluripotent stem cells (PSCs) promise to profoundly change our understanding of the development of the human brain and enable a detailed study of the pathogenesis of inherited and acquired brain diseases.

  13. Liturgical pharmacology: Time of the question, complexity and ethics

    Directory of Open Access Journals (Sweden)

    Calvyn C. du Toit


    Full Text Available Bernard Stiegler depicts technics as the human’s tertiary memory retention generating a pharmakon with both curative and malignant potential. He additionally rues the posthuman epoch’s depletion of a ‘time of the question’: revealed in the prevalent inaptitude for wisdom – scilicet long-term acuity. We offer Christian liturgy as an abeyant psychotechnique arcing the current pharmakon to cure through soliciting a ‘time of the question’. Rejuvenating Christian liturgy as a psychotechnique can bolster a broader societal ‘time of the question’. Firstly, we describe technic’s du jour mise on scène. Secondly, we constrain Christian liturgies as complex systems incorporating malleability, temporality, and instability. Thirdly, we imagine Christian liturgy as empty tradition allowing amateur repetition of ancient art enticing a ‘time of the question’. Keywords: Liturgy; Ethics; Technology; Stiegler; Complexity; Paul Cilliers; Van Huyssteen

  14. From Slash-and-burn to Disk Ploughing: The Land Policy and Tractors Behind Erosion and Forest Pioneer Farming in Southern Xayabury Province (Laos

    Directory of Open Access Journals (Sweden)

    Marc Dufumier


    Full Text Available Bordering Thailand, the southern part of Xayabury province is engaged in international trade and has experienced agricultural growth like nowhere else in Laos. The rapid transformation from manual slash-and-burn agriculture to mechanized, chemical-based cropping systems is often cited by Laotian authorities as a model of development. But a careful study of changes underway indicates that the reality is far less encouraging than it would appear at first. If many farmers have indeed bolstered their incomes over the last twenty years, it is no less true that some of the poorest peasants have become increasingly poorer and that the new techniques cause serious erosion, as they have not been able to prevent the expansion of cultivated areas on sloping lands.

  15. Are psychogenic non-epileptic seizures just another symptom of conversion disorder? (United States)

    Kanaan, Richard A A; Duncan, Roderick; Goldstein, Laura H; Jankovic, Joseph; Cavanna, Andrea E


    Psychogenic non-epileptic seizures (PNES) are classified with other functional neurological symptoms as 'Conversion Disorder', but there are reasons to wonder whether this symptomatology constitutes a distinct entity. We reviewed the literature comparing PNES with other functional neurological symptoms. We find eight studies that directly examined this question. Though all but one found significant differences-notably in presenting age, trauma history, and dissociation-they were divided on whether these differences represented an important distinction. We argue that the aetiological and mechanistic distinctions they support, particularly when bolstered by additional data, give reason to sustain a separation between these conditions. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.


    Directory of Open Access Journals (Sweden)

    Maria Loredana POPESCU


    Full Text Available Present condition of Romanian economy is (still! bad enough, given the yet existent (aftereffects of world economic and financial crisis, so that this economy badly needs bolstering up in any manner whatsoever; considering this perspective, and Romania’s tourism potential, Romania’s tourism sector can become a hub of/for economic recovery. But, in order to do this, Romania’s policymakers need not lose from sight Romania’s long term objectives, whilst trying to attain (just the short term ones. For the latter’ achievement fiscal policy is a main tool, but if this tool is used in extremis tourism sector will definitely suffer. On the other hand, it is also true fiscal policy, if used wisely, is more than able to be an essential tool with which one can enhance competitiveness of Romania’s tourism sector.

  17. The brown tree snake, an introduced pest species in the central Pacific Islands (United States)

    Fritts, Thomas H.; Rodda, Gordon H.


    The reproduction of endangered Mariana crows (Corvus kubaryi) is intensively monitored, nests are protected, and (when necessary) eggs or young are moved to the safety of lab conditions until they are less vulnerable to the threats in natural habitats. Barriers on tree trunks and judicious pruning of adjacent trees are used in attempts to exclude snakes from nest trees. Two birds unique to Guam--the Micronesian kingfisher (Halcyon cinnamomina cinnamomina) and Guam rail (Gallirallus owstoni)-- are maintained at captive propagation facilities on Guam and in mainland zoos. Studies of these and other species, in captivity and on nearby islands, are underway to bolster our biological understanding of their behavior, reproduction, habitat use, and population biology.

  18. Maternal Morbidity and Mortality: Identifying Opportunities to Improve Clinical Outcomes. (United States)

    Witcher, Patricia M; Sisson, Melissa C


    A better understanding of why women die during pregnancy, childbirth, or postpartum offers valuable insight into strategies aimed at preventing maternal deaths and arresting the progression in the severity of a complication. The rate of severe maternal morbidity and maternal mortality in the United States has been trending upward in recent years and has garnered national attention with concentration on bolstering reviews of maternal deaths and implementing patient safety initiatives. The obstetric nurse is in a unique position to improve maternal outcomes through the anticipation, recognition, and communication of the early warning signs of impending deterioration in maternal condition. Presented in the context of the conceptual model of Stephen Covey's Circle of Influence, the professional nurse can proactively influence maternal outcomes directly, with actions defined by the scope of professional nursing practice or indirectly through professional interactions with others. Advancing one's education, knowledge, and technical skills broadens the influential capacity.

  19. A Systematic Review of Community Engagement in the US Environmental Protection Agency’s Extramural Research Solicitations: Implications for Research Funders (United States)

    Yuen, Tina; Park, Alice N.; Seifer, Sarena D.


    Objectives. We systematically reviewed the Environmental Protection Agency, National Center for Environmental Research’s (NCER’s) requests for applications (RFAs) and identified strategies that NCER and other funders can take to bolster community engagement. Methods. We queried NCER’s publically available online archive of funding opportunities from fiscal years 1997 to 2013. From an initial list of 211 RFAs that met our inclusion criteria, 33 discussed or incorporated elements of community engagement. We examined these RFAs along 6 dimensions and the degree of alignments between them. Results. We found changes over time in the number of RFAs that included community engagement, variations in how community engagement is defined and expected, inconsistencies between application requirements and peer review criteria, and the inclusion of mechanisms supporting community engagement in research. Conclusions. The results inform a systematic approach to developing RFAs that support community engagement in research. PMID:26469656

  20. A Systematic Review of Community Engagement in the US Environmental Protection Agency's Extramural Research Solicitations: Implications for Research Funders. (United States)

    Yuen, Tina; Park, Alice N; Seifer, Sarena D; Payne-Sturges, Devon


    We systematically reviewed the Environmental Protection Agency, National Center for Environmental Research's (NCER's) requests for applications (RFAs) and identified strategies that NCER and other funders can take to bolster community engagement. We queried NCER's publically available online archive of funding opportunities from fiscal years 1997 to 2013. From an initial list of 211 RFAs that met our inclusion criteria, 33 discussed or incorporated elements of community engagement. We examined these RFAs along 6 dimensions and the degree of alignments between them. We found changes over time in the number of RFAs that included community engagement, variations in how community engagement is defined and expected, inconsistencies between application requirements and peer review criteria, and the inclusion of mechanisms supporting community engagement in research. The results inform a systematic approach to developing RFAs that support community engagement in research.

  1. Pharmacology education in undergraduate and graduate medical education in the United States. (United States)

    Candler, C; Ihnat, M; Huang, G


    Pharmacology is considered a core course for virtually every medical school in the world. Although the study and teaching of the properties of drug-like substances dates from at least ancient Greece and Egypt, Oswald Schmiedeberg (1838-1921) at the University of Strassburg in Germany is generally recognized as the founder of modern pharmacology. Schmiedeberg himself trained many of the first generation of modern academic pharmacologists, including the first chair of pharmacology in North America, John Jacob Abel at the University of Michigan. Furthermore, the discovery, development, and use of morphine during the U.S. Civil War bolstered the desire for future physicians to be taught about the properties of drugs, and by the 1890s almost every medical school had a course on drugs.

  2. Do You Really Expect Me to Get MST Care in a VA Where Everyone is Male Innovative Delivery of Evidence Based Psychotherapy to Women with Military Sexual Trauma (United States)


    relative to Veterans in PE-SD. Treatment gains include a reduction of PTSD and other psychiatric symptoms such depression , as well as more global...resources from MUSC to bolster online recruitment strategies (e.g., Facebook ads) and provide materials to study participants (e.g., bags with study...HBT  is   superior  to  PE  PE-­SD  across  critical  clinical  and  quality  of  life  outcomes  (i.e.,  PTSD,   depression ,  quality  of  life)  due

  3. Emerging trends in social media and plastic surgery. (United States)

    Gould, Daniel J; Leland, Hyuma A; Ho, Adelyn L; Patel, Ketan M


    Social media has increasingly changed the landscape of medicine and surgery and is rapidly expanding its influence in most peoples' lives. The average person spends nearly 2 hours per day using social media, consuming information about everything from family updates to entertainment news to presidential elections. The concentration of consumers on social media platforms has resulted in direct medicine and medical products marketing to consumers. Similarly, social media is increasingly becoming a platform for interaction between physicians and potential patients. Some physicians have taken this opportunity to better educate patients, while allowing patients to learn more about their surgeons online. These tools can increase internet traffic online to bonafide internet sites, as well as bolster marketing for many hospitals, hospital systems, and individual doctors. It can also serve to increase knowledge about procedures and conditions through direct outreach to patients. Social media is a powerful tool which needs to be utilized wisely to avoid pitfalls.

  4. Self-efficacy mediates the relationship of depressive symptoms and social support with adherence in patients with heart failure. (United States)

    Tovar, Elizabeth G; Dekker, Rebecca L; Chung, Misook L; Gokun, Yevgeniya; Moser, Debra K; Lennie, Terry A; Rayens, Mary Kay


    Poor self-care is common among adults with heart failure and leads to poor health outcomes. Low self-efficacy, depression, and low social support are associated with poor self-care, but knowledge about these relationships in heart failure is limited. Secondary data analysis of cross-sectional data from 346 adults with heart failure measuring self-efficacy, depressive symptoms, social support, and self-care adherence was conducted. Tests of mediation using multiple linear regressions indicate that self-efficacy fully mediates the relationships between depression and adherence, and social support and adherence. Bolstering self-efficacy may have a greater impact on self-care adherence than targeting either depression or social support alone. © The Author(s) 2015.

  5. Research into the origins and characteristics of unicorns: mental illness as the unicorn. (United States)

    Simon, L


    Basic research, particularly into the psychological and neurological underpinnings of schizophrenia and other "mental illnesses," is flawed because of its adherence to the ideology that unwanted, hard-to-understand behavior constitutes true medical illness. It is argued here that psychiatric diagnostic terms represent moral judgments rather than medical entities. By reducing experimental subjects to a moral label, and assuming that neurological differences associated with unwanted behavior are brain diseases, researchers fail to take into account the conscious experience, organization of self and self-image, patterns of motivation, history and social contexts of their patients. The failure to consider the psychology of their subjects renders the results of these studies ambiguous and irrelevant for any uses except bolstering the biomedical model of psychiatry.

  6. Social identity and the true believer: responses to threatened self-stereotypes among the intrinsically religious. (United States)

    Burris, C T; Jackson, L M


    That religion is an impactful social category has often been assumed but seldom tested. Based on social identity and self-categorization theories, it is argued that devout religious commitment reflects, at least in part, an individual's motivation to engage in religious self-stereotyping (i.e. to perceive oneself as an exemplary religious group member). In order to test this analysis, individuals scoring high or low on a measure of intrinsic religious orientation received false feedback that either threatened or bolstered their self-perceptions on a dimension of behaviour that was either important or not important to religious group membership. As expected, intrinsic orientation predicted increased religious self-stereotyping only when feedback was threatening and important to religious group membership; affective and behavioural indices revealed a similar pattern. Implications for the social identity/self-categorization literature, and for theory development in the psychology of religion, are subsequently discussed.

  7. L’immagine come arma. Il ruolo delle fotografie nella protesta di Euromaidan

    Directory of Open Access Journals (Sweden)

    Tamara Mykhaylyak


    Full Text Available The Euormaidan’s photos are known all around the world; this event has been described through a myriad of photos and videos. Throughout the exploration and analysis of the major Russian and Ukrainian  journals’ websites, online TVs, social networks and blogs, we have gathered a large amount of visual documents.  Intentionally we focused on the images produced by the protesters and the journalists that supported the protest. We decided to divide the analyzed photos into four categories: conflict, pain, memory and symbols. These categories reveal specific investments made on the photos, roles and functions bestowed to them with the purpose of bolster and strengthen the Euromaidan’s themes.

  8. Community-driven standards-based electronic laboratory data-sharing networks. (United States)

    Zarcone, Patina; Nordenberg, Dale; Meigs, Michelle; Merrick, Ulrike; Jernigan, Daniel; Hinrichs, Steven H


    Public health laboratories (PHLs) are critical components of the nation's healthcare system, serving as stewards of valuable specimens, delivering important diagnostic results to support clinical and public health programs, supporting public health policy, and conducting research. This article discusses the need for and challenges of creating standards-based data-sharing networks across the PHL community, which led to the development of the PHL Interoperability Project (PHLIP). Launched by the Association of Public Health Laboratories and the Centers for Disease Control and Prevention in September 2006, PHLIP has leveraged a unique community-based collaborative process, catalyzing national capabilities to more effectively share electronic laboratory-generated diagnostic information and bolster the nation's health security. PHLIP is emerging as a model of accelerated innovation for the fields of laboratory science, technology, and public health.

  9. Gender, technology change and globalization: the case of China. (United States)

    Guo, H; Zhao, M


    This paper reviews the experience of women workers in China while the country's economy is changing into a globalized, technologically advanced one. New computer-based technology is increasingly acknowledged as a powerful and pervasive force that can shape or, at least in many ways, affect employment. It is hailed for opening up fresh employment opportunities and reducing the physical stress involved in work. However, the possibilities of redundancies or intensification of workload also exist. By focusing on changes in women's work, the article reveals the contradictions inherent in following a development path based on ever-higher levels of technology in the context of an intensive mode of production, to which productivity is the core value. The economy is bolstered and some workers gain employment in expanding industries. However, workers, who lack access to training and who are reliant on the dwindling state support for their reproductive responsibilities, are marginalized and seek employment in the growing informal economy.

  10. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Gholamhosein Tavacoly


    Full Text Available   Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist , then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.   In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  11. PIXEL: Japanese InSAR community for crustal deformation research (United States)

    Furuya, M.; Shimada, M.; Ozawa, T.; Fukushima, Y.; Aoki, Y.; Miyagi, Y.; Kitagawa, S.


    In anticipation of the launch of ALOS (Advanced Land Observation Satellite) by JAXA (Japan Aerospace eXploration Agency), and in order to expand and bolster the InSAR community for crustal deformation research in Japan, a couple of scientists established a consortium, PIXEL, in November 2005 in a completely bottom-up fashion. PIXEL stands for Palsar Interferometry Consortium to Study our Evolving Land. Formally, it is a research contract between JAXA and Earthquake Research Institute (ERI), University of Tokyo. As ERI is a shared institute of the Japanese universities and research institutes, every scientist at all Japanese universities and institutes can participate in this consortium. The activity of PIXEL includes information exchange by mailing list, tutorial workshop for InSAR software, research workshop, and PALSAR data sharing. After the launch of ALOS, we have already witnessed several earthquakes and volcanic activities using PALSAR interferometry. We will briefly show and digest some of those observation results.

  12. Costs of global climate protection

    International Nuclear Information System (INIS)

    Krause, F.


    This paper discusses the cost implications of the air pollution abatement recommendations contained in a recently published IPSEP (International Project for Sustainable Energy Paths) study on the feasibility of the abatement of carbon dioxide emissions deemed significantly responsible for the greenhouse effect and its associated negative impacts on this planet's climatic equilibrium. The air pollution abatement strategies are to be enforced in five highly industrialized European countries - Germany, France, Great Britain, Italy and Holland. The study's overall results indicate the feasibility of 50% reductions in carbon dioxide emissions within the next 30 years even with a more than doubling of GNP's and a contemporaneous phase-out of nuclear power production, and all this taking place in a cost effective way and with increased employment. In addition, IPSEP's report states that the implementation of effective program management strategies would bolster Western Europe's competitiveness on a global scale

  13. Does action planning moderate the intention-habit interaction in the exercise domain? A three-way interaction analysis investigation. (United States)

    de Bruijn, Gert-Jan; Rhodes, Ryan E; van Osch, Liesbeth


    Both habit strength and action planning have been found to moderate the intention-exercise behaviour relationship, but no research exists that has investigated how habit strength and action planning simultaneously influence this relationship. The present study was designed to explore this issue in a prospective sample of undergraduate students (N = 415): action planning, habit strength, intention, attitudes, subjective norms and perceived behavioural control were assessed at baseline and exercise behaviour was assessed 2 weeks later. Both habit strength and action planning moderated the intention-exercise relationship, with stronger relationship at higher levels of planning or habit strength. Decomposing a significant action planning × habit strength × intention interaction showed that the strength of the intention-exercise relationship progressed linearly through levels of action planning and habit strength. These novel results show that action planning strengthens the intention-habit strength interaction in the exercise domain: exercise interventions should therefore focus on simultaneously bolstering action planning and habit strength.

  14. Smartphones in Surgery

    Directory of Open Access Journals (Sweden)

    Ara A. Salibian


    Full Text Available Smartphones have the capability of enhancing many aspects of the continuum of surgical care by providing an efficient means of multimedia communication among surgeons and healthcare personnel. The ability for mobile Internet and email access, along with features such as built-in cameras and video calling, allow surgeons to rapidly access, send and receive patient information without being restricted by issues of connectivity. Smartphones create an unrestricted network of data sharing, improving the flexibility of patient consultation, timeliness of preoperative preparation, efficiency of post-operative care and the effectiveness of a surgical team. Furthermore, smartphones provide mobile access to a multitude of surgical resources to bolster continued surgical education. This article presents a review of the current literature on the utilizations of smartphones in surgery, discusses their benefits and limitations, and addresses the possibility of incorporating smartphones into the protocol of surgical care.

  15. Negative thermal expansion near two structural quantum phase transitions (United States)

    Occhialini, Connor A.; Handunkanda, Sahan U.; Said, Ayman; Trivedi, Sudhir; Guzmán-Verri, G. G.; Hancock, Jason N.


    Recent experimental work has revealed that the unusually strong, isotropic structural negative thermal expansion in cubic perovskite ionic insulator ScF3 occurs in excited states above a ground state tuned very near a structural quantum phase transition, posing a question of fundamental interest as to whether this special circumstance is related to the anomalous behavior. To test this hypothesis, we report an elastic and inelastic x-ray scattering study of a second system Hg2I2 also tuned near a structural quantum phase transition while retaining stoichiometric composition and high crystallinity. We find similar behavior and significant negative thermal expansion below 100 K for dimensions along the body-centered-tetragonal c axis, bolstering the connection between negative thermal expansion and zero-temperature structural transitions. We identify the common traits between these systems and propose a set of materials design principles that can guide discovery of new materials exhibiting negative thermal expansion.

  16. Revision of Immediate Post-Open Heart Surgery Education for Critical Care RNs. (United States)

    Mowry, Marianne J; Gabel, Mollie A


    Responding to the complex nature of critical care is imperative, as extensive clinical judgment is required during those vital moments when patients are experiencing complications related to open heart surgery, post-vessel bypass, or valve replacement. Critical care registered nurses must rely on evidence-based foundational knowledge and skills particular to cardiovascular pathophysiology, hemodynamic monitoring, and medications. This article reports on the critical care educator's revision of the immediate post-open heart surgery curriculum. Mixed educational methods within the plan were foundational to develop clinicians for competent care of these complex patients (within the first 8 hours). The revision included experiential learning and learner centeredness to bolster the learner's confidence, reduce the time to competence, and, most important, ensure positive patient outcomes. Kirkpatrick's classic four-level model provided the framework for evaluation. Lessons learned were discussed following the program initiation. Copyright 2015, SLACK Incorporated.

  17. A Mixed-Method Study on Correlates of HIV-Related Stigma Among Gay and Bisexual Men in the Southern United States. (United States)

    Berg, Rigmor C; Carter, Dakota; Ross, Michael W

    Societal prejudice against people living with HIV infection is a formidable public health challenge that can negatively impact health and well-being. We recruited a multiethnic sample of 129 gay and bisexual men living with HIV who completed a brief survey; a subset of participants completed semi-structured qualitative interviews to contextualize the data. In bivariate analyses, stigma was positively and significantly correlated with depression (r = .402, p stigma and coping strategies the men had developed. Although some of the coping strategies reduced the likelihood of experiencing acts of stigmatization, they also exacerbated the psychological stress of living with a stigmatized disease and limited the potential for social support. Our results highlight the need to scale up stigma-reduction programs, particularly those that can bolster social support networks. Copyright © 2017 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

  18. The Individuals With Disabilities Education Act (IDEA) for Children With Special Educational Needs. (United States)

    Lipkin, Paul H; Okamoto, Jeffrey


    The pediatric health care provider has a critical role in supporting the health and well-being of children and adolescents in all settings, including early intervention (EI), preschool, and school environments. It is estimated that 15% of children in the United States have a disability. The Individuals with Disabilities Education Act entitles every affected child in the United States from infancy to young adulthood to a free appropriate public education through EI and special education services. These services bolster development and learning of children with various disabilities. This clinical report provides the pediatric health care provider with a summary of key components of the most recent version of this law. Guidance is also provided to ensure that every child in need receives the EI and special education services to which he or she is entitled. Copyright © 2015 by the American Academy of Pediatrics.

  19. Self-deception's adaptive value: effects of positive thinking and the winner effect. (United States)

    Lopez, Jason Kido; Fuxjager, Matthew J


    There is a puzzle about why self-deception, a process that obscures the truth, is so pervasive in human behavior given that tracking the truth seems important for our survival and reproduction. William von Hippel and Robert Trivers argue that, despite appearances, there is good reason to think that self-deception is an adaptation by arguing: (1) self-deception leads to a positive self-perception and (2) a positive self-perception increases an individual's fitness. D.S. Neil Van Leeuwen, however, gives persuasive arguments against both steps. In response, we will defend both propositions, thereby supporting the conclusion that self-deception indeed has adaptive value. The first premise will be bolstered by a survey of the philosophical literature and empirical work on self-deception, whereas the second will be strengthened by empirical research on a behavioral phenomenon known as the winner effect. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Land use and management change under climate change adaptation and mitigation strategies: a U.S. case study (United States)

    Mu, Jianhong E.; Wein, Anne; McCarl, Bruce


    We examine the effects of crop management adaptation and climate mitigation strategies on land use and land management, plus on related environmental and economic outcomes. We find that crop management adaptation (e.g. crop mix, new species) increases Greenhouse gas (GHG) emissions by 1.7 % under a more severe climate projection while a carbon price reduces total forest and agriculture GHG annual flux by 15 % and 9 %, respectively. This shows that trade-offs are likely between mitigation and adaptation. Climate change coupled with crop management adaptation has small and mostly negative effects on welfare; mitigation, which is implemented as a carbon price starting at $15 per metric ton carbon dioxide (CO2) equivalent with a 5 % annual increase rate, bolsters welfare carbon payments. When both crop management adaptation and carbon price are implemented the effects of the latter dominates.

  1. Climate warming drives local extinction: Evidence from observation and experimentation (United States)

    Panetta, Anne Marie; Stanton, Maureen L.; Harte, John


    Despite increasing concern about elevated extinction risk as global temperatures rise, it is difficult to confirm causal links between climate change and extinction. By coupling 25 years of in situ climate manipulation with experimental seed introductions and both historical and current plant surveys, we identify causal, mechanistic links between climate change and the local extinction of a widespread mountain plant (Androsace septentrionalis). Climate warming causes precipitous declines in population size by reducing fecundity and survival across multiple life stages. Climate warming also purges belowground seed banks, limiting the potential for the future recovery of at-risk populations under ameliorated conditions. Bolstered by previous reports of plant community shifts in this experiment and in other habitats, our findings not only support the hypothesis that climate change can drive local extinction but also foreshadow potentially widespread species losses in subalpine meadows as climate warming continues. PMID:29507884

  2. Materials for Active Engagement in Nuclear and Particle Physics Courses (United States)

    Loats, Jeff; Schwarz, Cindy; Krane, Ken


    Physics education researchers have developed a rich variety of research-based instructional strategies that now permeate many introductory courses. Carrying these active-engagement techniques to upper-division courses requires effort and is bolstered by experience. Instructors interested in these methods thus face a large investment of time to start from scratch. This NSF-TUES grant, aims to develop, test and disseminate active-engagement materials for nuclear and particle physics topics. We will present examples of these materials, including: a) Conceptual discussion questions for use with Peer Instruction; b) warm-up questions for use with Just in Time Teaching, c) ``Back of the Envelope'' estimation questions and small-group case studies that will incorporate use of nuclear and particle databases, as well as d) conceptual exam questions.

  3. Crafting AIDS policy in Brazil and Russia: State-civil societal ties, institutionalised morals, and foreign policy aspiration. (United States)

    Gómez, Eduardo J


    During the 1990s, Brazil and Russia diverged in their policy response to AIDS. This is puzzling considering that both nations were globally integrated emerging economies transitioning to democracy. This article examines to what extent international pressures and partnerships with multilateral donors motivated these governments to increase and sustain federal spending and policy reforms. Contrary to this literature, the cases of Brazil and Russia suggest that these external factors were not important in achieving these outcomes. Furthermore, it is argued that Brazil's policy response was eventually stronger than Russia's and that it had more to do with domestic political and social factors: specifically, AIDS officials' efforts to cultivate a strong partnership with NGOs, the absence of officials' moral discriminatory outlook towards the AIDS community, and the government's interest in using policy reform as a means to bolster its international reputation in health.

  4. Construal Level and Social Exclusion: Concrete Thinking Impedes Recovery From Social Exclusion. (United States)

    Pfundmair, Michaela; Lermer, Eva; Frey, Dieter; Aydin, Nilüfer


    Social exclusion is a painful experience. Recent research has shown, however, that coping with exclusion can be facilitated by favorable conditions. In the current research, we investigated whether construal level affects recovery from social exclusion. We hypothesized that an abstract vs. concrete mindset would moderate coping with exclusion. Indeed, lower compared to higher concrete thinking (Study 1) and abstract compared to concrete thinking (Study 2) bolstered the basic need of belonging when excluded. Priming of abstract thinking, moreover, increased participants' sense of belonging both in response to exclusion and inclusion relative to no priming (Study 3). Our results are the first to establish a relationship between construal level and social exclusion, thereby suggesting an alleviating "abstraction discount" effect for the consequences of social exclusion.

  5. Negative thermal expansion near two structural quantum phase transitions

    Energy Technology Data Exchange (ETDEWEB)

    Occhialini, Connor A.; Handunkanda, Sahan U.; Said, Ayman; Trivedi, Sudhir; Guzmán-Verri, G. G.; Hancock, Jason N.


    Recent experimental work has revealed that the unusually strong, isotropic structural negative thermal expansion in cubic perovskite ionic insulator ScF3 occurs in excited states above a ground state tuned very near a structural quantum phase transition, posing a question of fundamental interest as to whether this special circumstance is related to the anomalous behavior. To test this hypothesis, we report an elastic and inelastic x-ray scattering study of a second system Hg2I2 also tuned near a structural quantum phase transition while retaining stoichiometric composition and high crystallinity. We find similar behavior and significant negative thermal expansion below 100 K for dimensions along the body-centered-tetragonal c axis, bolstering the connection between negative thermal expansion and zero-temperature structural transitions.We identify the common traits between these systems and propose a set of materials design principles that can guide discovery of newmaterials exhibiting negative thermal expansion

  6. Mechanical properties of biocompatible clay/P(MEO2MA-co-OEGMA) nanocomposite hydrogels. (United States)

    Xiang, Hengxue; Xia, Mengge; Cunningham, Alexander; Chen, Wei; Sun, Bin; Zhu, Meifang


    The effects of crosslinking density, polymer concentration and monomer ratio on the mechanical properties (tensile and compressive properties) of biocompatible clay/P(MEO 2 MA-co-OEGMA) nanocomposite (NC) hydrogels were investigated. These novel NC hydrogels, composed of inorganic/organic networks, were prepared via in-situ free radical polymerization. The results showed that with increasing inorganic crosslinking agent, i.e. clay concentration, an increase in the tensile strength, elongation at break and compressive strength was observed. Similarly, with increasing polymer concentration, the tensile strength and compressive strength of the NC hydrogels increased while the elongation at break decreased. Increasing the molar concentration of OEGMA in the comonomer led to an increase in the tensile strength of the NC hydrogels but a reduction in the compressive strength. Moreover, clay/P(MEO 2 MA-co-OEGMA) NC hydrogels presented good biocompatibility bolstering their application as tissue engineering scaffolds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. "That was the Last Time I Saw my House": The Importance of Place Attachment among Children and Youth in Disaster Contexts. (United States)

    Scannell, Leila; Cox, Robin S; Fletcher, Sarah; Heykoop, Cheryl


    Place attachment is important for children and youth's disaster preparedness, experiences, recovery, and resilience, but most of the literature on place and disasters has focused on adults. Drawing on the community disaster risk reduction, recovery, and resilience literature as well as the literature on normative place attachment, children and youth's place-relevant disaster experiences are examined. Prior to a disaster, place attachments are postulated to enhance children and youth's disaster preparedness contributions and reinforce their pre-disaster resilience. During a disaster, damage of, and displacement from, places of importance can create significant emotional distress among children and youth. Following a disaster, pre-existing as well as new place ties can aid in their recovery and bolster their resilience moving forward. This framework enriches current theories of disaster recovery, resilience, and place attachment, and sets an agenda for future research. © Society for Community Research and Action 2016.

  8. Exploring the connections between green economy and informal economy in South Africa

    Directory of Open Access Journals (Sweden)

    Suzanne Smit


    Full Text Available The notion of an inclusive green economy in the context of sustainable development and poverty eradication requires an approach that engages with the informal economy. However, the informal economy is generally ignored or undervalued in discussions on the green economy. This paper set out to bolster this argument by identifying the ways in which the green economy and the informal economy may be connected by establishing the extent to which policies and plans relating to green economy connect with the informal economy, and recognising several informal green activities. The barriers and opportunities for connecting the two spheres were also explored as well as possible ways in which such activities may be supported at different levels of organisation. In the case of South Africa, many informal green activities that contribute to sustainable livelihoods are recognised. However, issues pertaining to procedure, process and participation hinder the transition to a truly inclusive green economy.

  9. Spliced

    DEFF Research Database (Denmark)

    Addison, Courtney Page


    Human gene therapy (HGT) aims to cure disease by inserting or editing the DNA of patients with genetic conditions. Since foundational genetic techniques came into use in the 1970s, the field has developed to the point that now three therapies have market approval, and over 1800 clinical trials have...... been initiated. In this article I present a brief history of HGT, showing how the ethical and practical viability of the field was achieved by key scientific and regulatory actors. These parties carefully articulated gene therapy’s scope, limiting it to therapeutic interventions on somatic cells......, and cultivated alliances and divisions that bolstered the field’s legitimacy. At times these measures faltered, and then practitioners and sometimes patients would invoke an ethical imperative, posing gene therapy as the best solution to life and death problems. I suggest that we consider how boundary...

  10. Therapeutic potential of carbohydrates as regulators of macrophage activation. (United States)

    Lundahl, Mimmi L E; Scanlan, Eoin M; Lavelle, Ed C


    It is well established for a broad range of disease states, including cancer and Mycobacterium tuberculosis infection, that pathogenesis is bolstered by polarisation of macrophages towards an anti-inflammatory phenotype, known as M2. As these innate immune cells are relatively long-lived, their re-polarisation to pro-inflammatory, phagocytic and bactericidal "classically activated" M1 macrophages is an attractive therapeutic approach. On the other hand, there are scenarios where the resolving inflammation, wound healing and tissue remodelling properties of M2 macrophages are beneficial - for example the successful introduction of biomedical implants. Although there are numerous endogenous and exogenous factors that have an impact on the macrophage polarisation spectrum, this review will focus specifically on prominent macrophage-modulating carbohydrate motifs with a view towards highlighting structure-function relationships and therapeutic potential. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Region III involvement in quality control and quality assurance of radon testing methods

    International Nuclear Information System (INIS)

    Coyle, F.T.


    Region III has set a goal of increasing the testing for radon by our residents. One approach to this goal, is to bolster the public's confidence in the testing laboratories. We believe that this can be done most effectively by assuring the quality of the measurements available to the public. All Proficient Laboratories and Pennsylvania Certified Laboratories have submitted a quality assurance (QA) program. A QA audit checklist has been developed which will be finalized and made available to the states in our Region. This paper deals with inspection, verification, and documentation of the various laboratories and their compliance with prudent measuring protocols and addresses the following items: Organization and responsibilities; Sampling procedures; Detector chain of custody; Measurement procedures, quality control checks; State certification and RMP; Data resection, validation, and reporting; Quality assurance reports to management; Interview and discussion of QA audit with responsible officer

  12. The emotional and attitudinal consequences of religious hypocrisy: experimental evidence using a cognitive dissonance paradigm. (United States)

    Yousaf, Omar; Gobet, Fernand


    We explored the emotional and attitudinal consequences of personal attitude-behavior discrepancies using a religious version of the hypocrisy paradigm. We induced cognitive dissonance in participants (n = 206) by making them feel hypocritical for advocating certain religious behaviors that they had not recently engaged in to their own satisfaction. In Experiment 1, this resulted in higher levels of self-reported guilt and shame compared to the control condition. Experiment 2 further showed that a religious self-affirmation task eliminated the guilt and shame. In Experiment 3, participants boosted their religious attitudes as a result of dissonance, and both religious and non-religious self-affirmation tasks eliminated this effect. The findings provide evidence that dissonance induced through religious hypocrisy can result in guilt and shame as well as an attitude bolstering effect, as opposed to the attitude reconciliation effect that is prevalent in previous dissonance research.

  13. How Unequal Is the United States? Adolescents' Images of Social Stratification. (United States)

    Flanagan, Constance A; Kornbluh, Mariah


    This study highlights the use of pictorial images to understand adolescents' views on social stratification. A continuum of five visual images of social stratification were presented to a diverse sample of five hundred ninety-eight 8th-12th graders (14-18 years old). Adolescents selected which image best represented the United States (today, in 20 years, how it ought to be). Images ranged from inequitable to egalitarian. Results supported reference group and possible selves theories. Adolescents in higher status families chose a more egalitarian image for how the United States is today and how it ought to be. African Americans considered the United States today more unequal. Differences in adolescents' commitment to an egalitarian ideal depended on their reactions to inequality and their beliefs about government responsiveness, bolstering the measure's validity. © 2017 The Authors. Child Development © 2017 Society for Research in Child Development, Inc.

  14. On the broad applicability of the affective circumplex: representations of affective knowledge among schizophrenia patients. (United States)

    Kring, Ann M; Barrett, Lisa Feldman; Gard, David E


    Studies of affective experience are guided by the assumption that the structure of affect generalizes across people. Yet this assumption has not been tested among educationally and economically diverse community residents or among individuals with psychopathology. This study explicitly examined the broad applicability of the valence-arousal circumplex and whether schizophrenia patients and nonpatients have comparable knowledge structures of affective phenomena. Patients and nonpatients completed similarity ratings of 120 pairs of affect words. Similarity judgments were analyzed separately for each group using a multidimensional scaling procedure, and solutions were compared. Results revealed the same two-dimensional valence-arousal solution for schizophrenia patients and nonpatients, although there were subtle differences between the groups. These findings provide additional evidence that the circumplex model is a useful formalism for representing affective phenomena across diverse populations, and they bolster confidence in existing interpretations of schizophrenia patients' reports of affective experience.

  15. A computer vision for animal ecology. (United States)

    Weinstein, Ben G


    A central goal of animal ecology is to observe species in the natural world. The cost and challenge of data collection often limit the breadth and scope of ecological study. Ecologists often use image capture to bolster data collection in time and space. However, the ability to process these images remains a bottleneck. Computer vision can greatly increase the efficiency, repeatability and accuracy of image review. Computer vision uses image features, such as colour, shape and texture to infer image content. I provide a brief primer on ecological computer vision to outline its goals, tools and applications to animal ecology. I reviewed 187 existing applications of computer vision and divided articles into ecological description, counting and identity tasks. I discuss recommendations for enhancing the collaboration between ecologists and computer scientists and highlight areas for future growth of automated image analysis. © 2017 The Author. Journal of Animal Ecology © 2017 British Ecological Society.

  16. Leadership and Management Are One and the Same. (United States)

    Azad, Neelam; Anderson, H Glenn; Brooks, Amie; Garza, Oscar; O'Neil, Christine; Stutz, Misty M; Sobotka, Jenelle L


    Defining the attributes of change catalysts within high functioning organizations, including the academic enterprise, is desirable. An understanding of these attributes within our academy may foster faculty interest and engagement in seeking administrative roles and serve to bolster succession planning within our schools. On one hand, there have been numerous publications teasing out the purported differences between leadership and management. On the other hand, does segregating these important characteristics based upon arbitrary distinctions do more harm than good? This commentary represents the work of a group of academic leaders participating in the 2015-2016 AACP Academic Leadership Fellowship Program. This work was presented as a debate at the 2016 AACP Interim Meeting in Tampa, Florida, in February 2016.

  17. Programming iOS 4 Fundamentals of iPhone, iPad, and iPod touch Development

    CERN Document Server

    Neuburg, Matt


    Get a solid grounding in all the fundamentals of Cocoa Touch, and avoid problems during iPhone and iPad app development. With Programming iOS 4, you'll dig into Cocoa and learn how to work effectively with Objective-C and Xcode. This book covers iOS 4 in a rigorous, orderly fashion-ideal whether you're approaching iOS for the first time or need a reference to bolster existing skills. Learn Objective-C language details and object-oriented programming conceptsUnderstand the anatomy of an Xcode project and all the stages of its lifecycleGrasp key Cocoa concepts such as relationships between clas

  18. Claudia Quinta (Pro Caelio 34 and an altar to Magna Mater

    Directory of Open Access Journals (Sweden)

    Eleanor Winsor Leach


    Full Text Available Among the items of sculpture from the Capitoline collection now housed in the Museum of the Power Station Montemartini is a marble relief altar of the Claudian Period (E. Simon's dating dedicated to the mater deorum and the navis salvia and depicting the arrival of the goddess Cybele at Rome by ship. The dedicator is one Claudia Syntyche and the sculpture alludes to the legends attached to a much honored woman of the Claudian family whom Cicero, in his oration pro Caelio brought on stage in a cameo appearance to bolster his case against the controversial contemporary woman Clodia Metelli as one of the accusers of his client M. Caelius Rufus. This paper will consider questions raised by the iconography of the altar with reference to the development of Claudia's legend in Roman mythology and subsequently ask who was this Claudia the dedicator and why did she choose Magna Mater for her vow?

  19. You didn't have to do that: belief in free will promotes gratitude. (United States)

    MacKenzie, Michael J; Vohs, Kathleen D; Baumeister, Roy F


    Four studies tested the hypothesis that a weaker belief in free will would be related to feeling less gratitude. In Studies 1a and 1b, a trait measure of free will belief was positively correlated with a measure of dispositional gratitude. In Study 2, participants whose free will belief was weakened (vs. unchanged or bolstered) reported feeling less grateful for events in their past. Study 3 used a laboratory induction of gratitude. Participants with an experimentally reduced (vs. increased) belief in free will reported feeling less grateful for the favor. In Study 4, a reduced (vs. increased) belief in free will led to less gratitude in a hypothetical favor scenario. This effect was serially mediated by perceiving the benefactor as having less free will and therefore as being less sincerely motivated. These findings suggest that belief in free will is an important part of being able to feel gratitude. © 2014 by the Society for Personality and Social Psychology, Inc.

  20. Phased Retrofits in Existing Homes in Florida Phase II: Shallow Plus Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    Sutherland, K. [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States); Parker, D. [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States); Martin, E. [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States); Chasar, D. [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States); Amos, B. [Building America Partnership for Improved Residential Construction (BA-PIRC), Cocoa, FL (United States)


    Originally published in February 2016, this revision contains an added section called 'Evaluation of Complete Central System Replacement with Inverter-Driven Heat Pump,' which presents the designs and energy savings evaluations of two different schemes wherein inverter-driven systems replaced a home’s existing central system. Analyses for three additional retrofit measures were bolstered by longer-term data; these are described in the sections on supplemental mini-split heat pumps (MSHPs), smart thermostats, and heat pump clothes dryers. The sections on supplemental MSHPs and smart thermostats were also enhanced with larger sample sizes and projections of weather-normalized annual energy savings. Finally, peak system hour energy demand-reduction predictions are provided for all retrofit measures where meaningful impacts could be drawn.

  1. Phased Retrofits in Existing Homes in Florida Phase II: Shallow Plus Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    Sutherland, K. [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States); Parker, D. [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States); Martin, E. [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States); Chasar, D. [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States); Amos, B. [Building America Partnership for Improved Residential Construction, Cocoa, FL (United States)


    Originally published in February 2016, this revision contains an added section called 'Evaluation of Complete Central System Replacement with Inverter-Driven Heat Pump,' which presents the designs and energy savings evaluations of two different schemes wherein inverter-driven systems replaced a home's existing central system. Analyses for three additional retrofit measures were bolstered by longer-term data; these are described in the sections on supplemental mini-split heat pumps (MSHPs), smart thermostats, and heat pump clothes dryers. The sections on supplemental MSHPs and smart thermostats were also enhanced with larger sample sizes and projections of weather-normalized annual energy savings. Finally, peak system hour energy demand-reduction predictions are provided for all retrofit measures where meaningful impacts could be drawn.

  2. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Gholamhosein Tavacoly


    Full Text Available Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist , then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.   In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  3. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Tavacoli, Gh


    Full Text Available Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist, then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences; the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  4. Revealing the Structural Neural Circuitry of Attention Deficit Hyperactivity Disorder With Diffusion MRI: Implications for Future Diagnosis and Treatment. (United States)

    Adisetiyo, Vitria


    Rates of attention deficit hyperactivity disorder (ADHD) diagnosis and psychostimulant prescriptions continue to rise, yet there are no clear diagnostic tests or biomarkers for the disorder. The purpose of this article is to highlight the role of diffusion MRI in bolstering a neurobiologic conceptualization of ADHD and how this holds promise for optimizing future diagnosis. Diffusion MRI is a powerful neuroimaging tool for noninvasive assessment of the structural neural circuitry underlying brain function and behavior. Though the modality is still in its infancy, diffusion MRI studies are showing neural network disruption in ADHD consistent with findings from other imaging modalities. Given the mounting evidence of brain-behavior correlates in ADHD, it is likely that imaging-based biomarkers will one day be incorporated into clinical diagnosis and treatment evaluation. Until then, diffusion MRI findings serve to validate ADHD as a brain-based disorder with immediate public health implications for individuals with ADHD.

  5. Mental Health Promotion in Public Health: Perspectives and Strategies From Positive Psychology (United States)

    Seligman, Martin E.P.; Peterson, Christopher; Diener, Ed; Zack, Matthew M.; Chapman, Daniel; Thompson, William


    Positive psychology is the study of what is “right” about people—their positive attributes, psychological assets, and strengths. Its aim is to understand and foster the factors that allow individuals, communities, and societies to thrive. Cross-sectional, experimental, and longitudinal research demonstrates that positive emotions are associated with numerous benefits related to health, work, family, and economic status. Growing biomedical research supports the view that positive emotions are not merely the opposite of negative emotions but may be independent dimensions of mental affect. The asset-based paradigms of positive psychology offer new approaches for bolstering psychological resilience and promoting mental health. Ultimately, greater synergy between positive psychology and public health might help promote mental health in innovative ways. PMID:21680918

  6. All Aboard the Desistance Line: First Stop, Producing Prosocial Prison Attachments within an HIV Prison-Based Peer Program

    Directory of Open Access Journals (Sweden)

    kimberly A. collica-cox


    Full Text Available This article explores the importance of social bonds in facilitating an investment in prosocial behavior amongst female prisoners working as HIV peer educators. Female prisoners can lack strong prosocial attachments to both individuals and institutions prior to incarceration. Absent this bond, little prevents the female prisoner from recidivating. Prison provides an opportunity to fashion new attachments that will assist in the reintegrative process. One way to create strong bonds of attachment, particularly for women, is through working as an HIV peer educator while incarcerated. In order to measure attachment levels, interviews were conducted with 49 female prisoners who worked in two HIV prison-based peer programs during their incarceration. Female peers developed strong attachments to one another. Such attachments were formed while incarcerated and were maintained upon release, thus serving to bolster support for newfound prosocial identities.

  7. Reading, writing, and reserve: Literacy activities are linked to hippocampal volume and memory in multiple sclerosis. (United States)

    Sumowski, James F; Rocca, Maria A; Leavitt, Victoria M; Riccitelli, Gianna; Meani, Alessandro; Comi, Giancarlo; Filippi, Massimo


    Engagement in cognitive leisure activities during early adulthood has been linked to preserved memory and larger hippocampal volume in persons with multiple sclerosis (MS). To investigate which specific types of cognitive leisure activities contribute to hippocampal volume and memory. We investigated links between three types of cognitive activities (Reading-Writing, Art-Music, Games-Hobbies) and (a) hippocampal volume within independent samples of Italian (n=187) and American (n=55) MS patients and (b) memory in subsamples of Italian (n=97) and American (n=53) patients. Reading-Writing was the only predictor of hippocampal volume (rp=.204, p=.002), and the best predictor of memory (rp=.288, p=.001). Findings inform the development of targeted evidence-based enrichment programs aiming to bolster reserve against memory decline. © The Author(s), 2016.

  8. Perceived control qualifies the effects of threat on prejudice. (United States)

    Greenaway, Katharine H; Louis, Winnifred R; Hornsey, Matthew J; Jones, Janelle M


    People sometimes show a tendency to lash out in a prejudiced manner when they feel threatened. This research shows that the relationship between threat and prejudice is moderated by people's levels of perceived control: Threat leads to prejudice only when people feel concurrently low in control. In two studies, terrorist threat was associated with heightened prejudice among people who were low in perceived control over the threat (Study 1; N = 87) or over their lives in general (Study 2; N = 2,394), but was not associated with prejudice among people who were high in perceived control. Study 3 (N = 139) replicated this finding experimentally in the context of the Global Financial Crisis. The research identifies control as an important ingredient in threatening contexts that, if bolstered, can reduce general tendencies to lash out under threat. © 2013 The British Psychological Society.

  9. Psychical research and the origins of American psychology (United States)

    Sommer, Andreas


    Largely unacknowledged by historians of the human sciences, late-19th-century psychical researchers were actively involved in the making of fledgling academic psychology. Moreover, with few exceptions historians have failed to discuss the wider implications of the fact that the founder of academic psychology in America, William James, considered himself a psychical researcher and sought to integrate the scientific study of mediumship, telepathy and other controversial topics into the nascent discipline. Analysing the celebrated exposure of the medium Eusapia Palladino by German-born Harvard psychologist Hugo Münsterberg as a representative example, this article discusses strategies employed by psychologists in the United States to expel psychical research from the agenda of scientific psychology. It is argued that the traditional historiography of psychical research, dominated by accounts deeply averse to its very subject matter, has been part of an ongoing form of ‘boundary-work’ to bolster the scientific status of psychology. PMID:23355763

  10. Religion and health connection: a study of African American, Protestant Christians. (United States)

    Gonnerman, Melvin E; Lutz, Gene M; Yehieli, Michele; Meisinger, Bruce K


    The roles religious and health promoting behaviors may play in bolstering positive physical and emotional health were assessed using structured, face-to-face interviews conducted using a non-random community sample of 105 adult African American, Protestant Christians in a small city in a rural state in the Midwest. The interview measured health promotion, health locus of control beliefs, emotional health, physical health, religious practices, and demographics. Health promotion, church attendance, or both were related to decreased prevalence of loneliness, depression, trouble sleeping, and family problems. More than 80% of those interviewed ascribed healing power to God and prayer. There was an apparent lack of connection between respondents' attitudes about faith and healing and their actual experiences.

  11. Historical time in the age of big data: Cultural psychology, historical change, and the Google Books Ngram Viewer. (United States)

    Pettit, Michael


    Launched in 2010, the Google Books Ngram Viewer offers a novel means of tracing cultural change over time. This digital tool offers exciting possibilities for cultural psychology by rendering questions about variation across historical time more quantitative. Psychologists have begun to use the viewer to bolster theories about a historical shift in the United States from a more collectivist to individualist form of selfhood and society. I raise 4 methodological cautions about the Ngram Viewer's use among psychologists: (a) the extent to which print culture can be taken to represent culture as a whole, (b) the difference between viewing the past in terms of trends versus events, (c) assumptions about the stability of a word's meaning over time, and (d) inconsistencies in the scales and ranges used to measure change over time. The aim is to foster discussion about the standards of evidence needed for incorporating historical big data into empirical research. (c) 2016 APA, all rights reserved).

  12. Women in Science and Engineering Building Community Online (United States)

    Kleinman, Sharon S.

    This article explores the constructs of online community and online social support and discusses a naturalistic case study of a public, unmoderated, online discussion group dedicated to issues of interest to women in science and engineering. The benefits of affiliation with OURNET (a pseudonym) were explored through participant observation over a 4-year period, telephone interviews with 21 subscribers, and content analysis of e-mail messages posted to the discussion group during a 125-day period. The case study findings indicated that through affiliation with the online discussion group, women in traditionally male-dominated fields expanded their professional networks, increased their knowledge, constituted and validated positive social identities, bolstered their self-confidence, obtained social support and information from people with a wide range of experiences and areas of expertise, and, most significantly, found community.

  13. Fitting in or opting out: A review of key social-psychological factors influencing a sense of belonging for women in physics (United States)

    Lewis, Karyn L.; Stout, Jane G.; Pollock, Steven J.; Finkelstein, Noah D.; Ito, Tiffany A.


    [This paper is part of the Focused Collection on Gender in Physics.] A number of cultural, social, environmental, and biological factors have been suggested to explain women's relatively lower representation in physics and other science, technology, engineering, and math (STEM) fields. Given its persistence, the causes of gender disparities are likely to be complex and multiply determined. In this review paper, we discuss how a sense of belonging relates to women's interest, persistence, and achievement in physics. We explore what it means to "fit in" and belong in academic contexts, the situational and interpersonal antecedents to belonging, and the consequences of a lack of belonging. We review the empirical evidence for the efficacy of interventions designed to bolster a sense of belonging. Based on these interventions we conclude the paper with a number of practical recommendations to affirm women's sense of belonging and create more welcoming and inclusive physics environments for all students.

  14. Introducing a psychosomatic medicine interest group for psychiatry residents. (United States)

    Puri, Neil V; Azzam, Pierre; Gopalan, Priya


    Having gained subspecialty certification in 2003, the field of psychosomatic medicine (PM) addresses the mental health needs of individuals who suffer from general medical conditions. The rising prevalence of chronic illness, along with trends in medical delivery toward more collaborative models of care, underscores the value of recruitment to PM specialty programs. To foster interest and education in PM, we have developed and implemented a Psychosomatic Medicine Interest Group for trainees within a psychiatry residency program. Participants have found the Psychosomatic Medicine Interest Group to be an enjoyable experience that has improved their clinical practice and interest in PM. The Psychosomatic Medicine Interest Group has also been a successful vehicle to enhance clinical knowledge and mentoring opportunities during training, while bolstering residents' desire to pursue a career in PM. Copyright © 2015 The Academy of Psychosomatic Medicine. All rights reserved.

  15. Dermatology training and practice in Australia. (United States)

    Sebaratnam, Deshan F; Murrell, Dédée F


    Dermatology is a relatively young discipline in Australia compared to other specialities within the medical fraternity. From its humble beginnings, the profession has evolved significantly over the decades and is now represented by the Australasian College of Dermatologists which is charged with training the next generation of dermatologists and advocating for and advancing the profession. The authors reviewed and describe the history of dermatology training and practice in Australia. Despite the progress in education, there are only 415 dermatologists serving a population of 23.3 million (1 per 58 000) and yet it has the highest incidence and prevalence of skin cancer in the world. The scope of clinical practice is wide in Australia, with clinicians well versed in medical and procedural dermatology. It is hoped that Australian dermatology will continue to bolster the dermatology profession globally. © 2014 The International Society of Dermatology.

  16. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    International Nuclear Information System (INIS)

    Tucker, Jo A.; Jochems, Caroline; Gulley, James L.; Schlom, Jeffrey; Tsang, Kwong Y.


    Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies

  17. Social media as social capital of LGB individuals in Hong Kong: its relations with group membership, stigma, and mental well-being. (United States)

    Chong, Eddie S K; Zhang, Yin; Mak, Winnie W S; Pang, Ingrid H Y


    Social media are found to facilitate social information exchange among lesbian, gay, and bisexual (LGB) individuals who are subjected to social stigma. This study tested the protective role of LGB-tailored social media uses and gratifications in promoting LGB group membership, which we hypothesized to reduce LGB stigma and enhance mental health among LGB individuals in Hong Kong. Based on a sample of 233 Chinese LGB individuals in Hong Kong, structural equation modeling showed evidence for our hypotheses, χ(df=62)(2)= 88.20, GFI = 0.95, CFI = 0.98, NNFI = 0.98, SRMR = 0.07, RMSEA = 0.04. Community surveillance, identity expression, and emotional support on social media may promote mental health by instilling a sense of group membership and reducing stigma. Social media may build camaraderie and bolster resilience among LGB individuals that may otherwise be difficult in conservative regions.

  18. The Concept of Alliance as an Image and Positioning Instrument for Institutions of Higher Learning

    Directory of Open Access Journals (Sweden)

    Víctor Manuel Alcántar Enríquez


    Full Text Available The present work provides a foundation for the concept of alliance which includes the ability of this to foster the university’s societal position as based on public perception of the institution. Accordingly, the work briefly addresses the development of the university’s collaboration with the productive sector, and emphasizes the need for institutions of higher learning to consider as well, those social sectors (including the government outside the realm of industry or technological expansion. The study concludes by affirming that alliance can become an effective instrument for promoting the university. It is therefore necessary to research the social perception of the university as a means of bolstering its relevance.

  19. Science and Technology Review January/February 2011

    Energy Technology Data Exchange (ETDEWEB)

    Blobaum, K J


    This month's issue has the following articles: (1) World's Most Intense X-Ray Laser Focuses on Livermore Science - Commentary by William H. Goldstein; (2) Groundbreaking Science with the World's Brightest X Rays - Experiments with x rays of unparalleled brightness and extremely short duration aim to reveal new information about atoms and molecules in motion; (3) From Data to Discovery - Ongoing control system enhancements at the National Ignition Facility bolster the understanding of experimental data and keep the system performing at its peak; (4) The Sun in All Its Splendor - Onboard the Solar Dynamics Observatory, Livermore-developed multilayer mirrors are enabling unprecedented full-disk, high-resolution images of the Sun; and (5) Drilling Deep into Plant Veins - A novel combination of imaging techniques is being used to understand the three-dimensional architecture of plant cell walls.

  20. Incorporation of Immune Checkpoint Blockade into Chimeric Antigen Receptor T Cells (CAR-Ts: Combination or Built-In CAR-T

    Directory of Open Access Journals (Sweden)

    Dok Hyun Yoon


    Full Text Available Chimeric antigen receptor (CAR T cell therapy represents the first U.S. Food and Drug Administration approved gene therapy and these engineered cells function with unprecedented efficacy in the treatment of refractory CD19 positive hematologic malignancies. CAR translation to solid tumors is also being actively investigated; however, efficacy to date has been variable due to tumor-evolved mechanisms that inhibit local immune cell activity. To bolster the potency of CAR-T cells, modulation of the immunosuppressive tumor microenvironment with immune-checkpoint blockade is a promising strategy. The impact of this approach on hematological malignancies is in its infancy, and in this review we discuss CAR-T cells and their synergy with immune-checkpoint blockade.

  1. IOT Based Smart Public Transport System

    Directory of Open Access Journals (Sweden)

    Parag Gawade


    Full Text Available Internet of Things IoT joins the objects of this present reality to the virtual world and empowers at whatever time anyplace network for anything that has a turn ON and turn OFF switch. It constitutes to a world where physical things and humans and other living things and virtual information and situations collaborate with each other. Substantial measure of information is created as expansive number of gadgets is associated with the web. So this expansive measure of information must be controlled and changed over to helpful data keeping in mind the end goal to create productive frameworks. In this paper we concentrate on to a urban IoT framework that is utilized to construct Intelligent Transportation System ITS. IoT based intelligent transportation systems are intended to bolster the Smart City vision which intends to utilize the progressed and capable communication systems for the organization of the city and the residents.

  2. Finding revelation in anthropology: Alexander Winchell, William Robertson Smith and the heretical imperative. (United States)

    Livingstone, David N


    Anthropological inquiry has often been considered an agent of intellectual secularization. Not least is this so in the sphere of religion, where anthropological accounts have often been taken to represent the triumph of naturalism. This metanarrative, however, fails to recognize that naturalistic explanations could sometimes be espoused for religious purposes and in defence of confessional creeds. This essay examines two late nineteenth-century figures--Alexander Winchell in the United States and William Robertson Smith in Britain--who found in anthropological analysis resources to bolster rather than undermine faith. In both cases these individuals found themselves on the receiving end of ecclesiastical censure and were dismissed from their positions at church-governed institutions. But their motivation was to vindicate divine revelation, in Winchell's case from the physical anthropology of human origins and in Smith's from the cultural anthropology of Semitic ritual.

  3. Incorporation of Immune Checkpoint Blockade into Chimeric Antigen Receptor T Cells (CAR-Ts): Combination or Built-In CAR-T. (United States)

    Yoon, Dok Hyun; Osborn, Mark J; Tolar, Jakub; Kim, Chong Jai


    Chimeric antigen receptor (CAR) T cell therapy represents the first U.S. Food and Drug Administration approved gene therapy and these engineered cells function with unprecedented efficacy in the treatment of refractory CD19 positive hematologic malignancies. CAR translation to solid tumors is also being actively investigated; however, efficacy to date has been variable due to tumor-evolved mechanisms that inhibit local immune cell activity. To bolster the potency of CAR-T cells, modulation of the immunosuppressive tumor microenvironment with immune-checkpoint blockade is a promising strategy. The impact of this approach on hematological malignancies is in its infancy, and in this review we discuss CAR-T cells and their synergy with immune-checkpoint blockade.

  4. Cryogenically cooled monochromators for the Advanced Photon Source

    International Nuclear Information System (INIS)

    Mills, D.M.


    The use of cryogenically cooled monochromators looks to be a very promising possibility for the Advanced Photon Source. This position has recently been bolstered by several experiments performed on beamlines at the ESRF and CHESS. At the ESRF, several crystal geometries have been tested that were designed for high power densities (approx-gt 150 W/mm 2 ) and moderate total absorbed powers (<200 W). These geometries have proven to be very successful at handling these power parameters with measured strains on the arc-second level. The experiments performed at CHESS were focused on high total power (approx-gt 1000 W) but moderate power densities. As with the previously mentioned experiments, the crystals designed for this application performed superbly with no measurable broadening of the rocking curves on the arc-second level. These experiments will be summarized and, based on these results, the performance of cryogenic monochromators for the APS will be assessed. copyright 1996 American Institute of Physics

  5. Changing public perceptions of genetically modified foods

    DEFF Research Database (Denmark)

    Scholderer, Joachim; Bech-Larsen, Tino; Grunert, Klaus G.


    and values. Two policies can be adopted in such a situation: (a) consumers can be actively informed regarding the risks and benefits and (b) consumers can be given the opportunity to evaluate products on the basis of direct experience. The effectiveness of both policies was tested in two experiments....... In esperiment 1, attitude change experiments were conducted with consumers from Denmark, Germany, Italy and the UK (N=1650). Different information strategies were tested against a control group for their ability to change consumers' attitudes and their influence on product choice. Results indicate...... that no attitude change occured. Instead, all strategies seemed to bolster pre-existing attitudes, thereby significantly decreasing consumers' preferences for GM products. The effect did not occur when consumers only saw a labeled product example. In experiment 2, we tested the effects of direct experience...

  6. Changing public perceptions of genetically modified foods: Effects of consumer information and direct product experience

    DEFF Research Database (Denmark)

    Scholderer, Joachim; Bech-Larsen, Tino; Grunert, Klaus G.

    and values. Two policies can be adopted in such a situation: (a) consumers can be actively informed regarding the risks and benefits and (b) consumers can be given the opportunity to evaluate products on the basis of direct experience. The effectiveness of both policies was tested in two experiments....... In experiment 1, attitude change experiments were conducted with consumers from Denmark, Germany, Italy and the UK (N=1650). Different information strategies were tested against a control group for their ability to change consumers' attitudes and their influence on product choice. Results indicate...... that no attitude change occured. Instead, all stategies seemed to bolster pre-existing attitudes, thereby significantly decreasing consumers' preferences for GM products. The effect did not occur when consumers only saw a labeled product example. In experiment 2, we tested the effects of direct experience...

  7. Is it time to revisit contraindications to organ donation from donors with a JAK-2 mutation? Safe use of a liver allograft from a donor with essential thrombocythaemia. (United States)

    Haldar, Debashis; Chen, Frederick; Byron, Jane; Elsharkawy, Ahmed Mohamed; Perera, M Thamara Pr


    Transplantation can cure end-stage liver disease and hepatocellular carcinoma. However, the balance of organ demand and provision is heavily tipped to the detriment of patients. Patients awaiting transplantation rely on the greater use of marginal donors that may carry a risk to the recipient. UK authorities have decreed donor haematological malignancy an absolute contraindication. The authors describe the first report of a patient being safely transplanted with a liver from a donor who suffered from JAK2 V617F mutation-driven essential thrombocythaemia to a patient with a critical burden of hepatocellular carcinoma. A year after transplantation, the patient has neither evidence of acquisition of the donor's pathology, nor evidence of carcinoma recurrence. The case highlights the responsibility of the recipient team to maximize the use of organs by expert risk assessment. Dissemination of experience should inform future decisions, benefit patients and bolster utility in an era of growing waiting-list mortality. © 2015 Steunstichting ESOT.

  8. Embodied cognition and STEM learning: overview of a topical collection in CR:PI. (United States)

    Weisberg, Steven M; Newcombe, Nora S


    Embodied learning approaches emphasize the use of action to support pedagogical goals. A specific version of embodied learning posits an action-to-abstraction transition supported by gesture, sketching, and analogical mapping. These tools seem to have special promise for bolstering learning in science, technology, engineering, and mathematics (STEM) disciplines, but existing efforts need further theoretical and empirical development. The topical collection in Cognitive Research: Principles includes articles aiming to formalize and test the effectiveness of embodied learning in STEM. The collection provides guideposts, staking out the terrain that should be surveyed before larger-scale efforts are undertaken. This introduction provides a broader context concerning mechanisms that can support embodied learning and make it especially well suited to the STEM disciplines.

  9. Microbial fuel cells: recent developments in design and materials (United States)

    Bhargavi, G.; Venu, V.; Renganathan, S.


    Microbial Fuel Cells (MFCs) are the promising devices which can produce electricity by anaerobic fermentation of organic / inorganic matter from easily metabolized biomass to complex wastewater using microbes as biocatalysts. MFC technology has been found as a potential technology for electricity generation and concomitant wastewater treatment. However, the high cost of the components and low efficiency are barricading the commercialization of MFC when compared with other energy generating systems. The performance of an MFC is largely relying on the reactor design and electrode materials. On the way to improve the efficiency of an MFC, tremendous exercises have been carried out to explore new electrode materials and reactor designs in recent decades. The current review is excogitated to amass the progress in design and electrode materials, which could bolster further investigations on MFCs to improve their performance, mitigate the cost and successful implementation of technology in field applications as well.

  10. Determinants of Scale Efficiency in the Brazilian Third-Party Logistics Industry from 2001 to 2009

    Directory of Open Access Journals (Sweden)

    Peter F. Wanke


    Full Text Available This article investigates the Brazilian third-party logistics (3PL sector which, increasingly competitive, offers clients a wide variety of services/information technologies in the quest to bolster efficiency. The main research objective is to determine which variables significantly impact 3PLs scale efficiency by applying two-stage DEA (Data Envelopment Analysis. Based on an unbalanced panel model, data from the annual study published by Revista Tecnologística (years 2001–2009 were analyzed. Results corroborate evidence in the literature that coordination mechanisms in the supply chain, supported by the availability of real time information and inventory synchronization, favor a more rational allocation of resources (inputs to client demands (outputs.

  11. Older Adult Video Game Preferences in Practice: Investigating the Effects of Competing or Cooperating. (United States)

    Souders, Dustin J; Boot, Walter R; Charness, Neil; Moxley, Jerad H


    Video game interventions with the aim to improve cognition have shown promise for both younger (e.g., Powers et al., 2013) and older adults (e.g., Toril, Reales, and Ballesteros, 2014). Most studies suggest that fast-paced action games produce the largest benefits, but a recent video game intervention with older adults found that an action game intervention can result in poor adherence (Boot et al., 2013). To increase intervention adherence, we investigated older adult video game preferences that might bolster adherence by having participants play a competitive game (Mario Kart DS) or a cooperative game (Lego Star Wars: The Complete Saga) alone or with a partner. Although hypotheses regarding cooperative and multi-player gameplay were not supported, converging evidence suggests multi-player game play may lead to greater enjoyment, which was related to intervention adherence in a previous study (Boot et al., 2013). Insights for gaming intervention studies in older populations are also provided.

  12. Personality predicts working-memory-related activation in the caudal anterior cingulate cortex. (United States)

    Gray, Jeremy R; Braver, Todd S


    Behavioral studies suggest that two affective dimensions of personality are associated with working memory (WM) function. WM load is known to modulate neural activity in the caudal anterior cingulate cortex (ACC), a brain region critical for the cognitive control of behavior. On this basis, we hypothesized that neural activity in the caudal ACC during a WM task should be associated with personality: correlated negatively with behavioral approach sensitivity (BAS) and positively with behavioral inhibition sensitivity (BIS). Using functional magnetic resonance imaging, we measured brain activity in 14 participants performing a three-back WM task. Higher self-reported BAS predicted better WM performance (r = .27) and lower WM-related activation in the caudal ACC (r = -.84), suggesting personality differences in cognitive control. The data bolster approach-withdrawal (action control) theories of personality and suggest refinements to the dominant views of ACC and personality.

  13. Advanced Supersonic Nozzle Concepts: Experimental Flow Visualization Results Paired With LES (United States)

    Berry, Matthew; Magstadt, Andrew; Stack, Cory; Gaitonde, Datta; Glauser, Mark; Syracuse University Team; The Ohio State University Team


    Advanced supersonic nozzle concepts are currently under investigation, utilizing multiple bypass streams and airframe integration to bolster performance and efficiency. This work focuses on the parametric study of a supersonic, multi-stream jet with aft deck. The single plane of symmetry, rectangular nozzle, displays very complex and unique flow characteristics. Flow visualization techniques in the form of PIV and schlieren capture flow features at various deck lengths and Mach numbers. LES is compared to the experimental results to both validate the computational model and identify limitations of the simulation. By comparing experimental results to LES, this study will help create a foundation of knowledge for advanced nozzle designs in future aircraft. SBIR Phase II with Spectral Energies, LLC under direction of Barry Kiel.

  14. Modeling of nanotoxicity molecular interactions of nanomaterials with bionanomachines

    CERN Document Server

    Zhou, Ruhong


    This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines. It lays out the fundamentals of nanotoxicity modeling for an array of nanomaterial systems, ranging from carbon-based nanoparticles to noble metals, metal oxides, and quantum dots. The author illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling approaches can be applied to bolster our understanding of many important aspects of this critical nanotoxicity issue. Each chapter is organized by types of nanomaterials for practicality, making this an ideal book for senior undergraduate students, graduate students, and researchers in nanotechnology, chemistry, physics, molecular biology, and computer science. It is also of interest to academic and industry professionals who work on nanodrug delivery and related biomedical applications, and aids readers in their biocompatibility assessment efforts in the coming age of nanotechnology...

  15. Innovation adoption as facilitated by a change-oriented workplace. (United States)

    Becan, Jennifer E; Knight, Danica K; Flynn, Patrick M


    One of the unique contributions of this study is a glimpse into the process by which counselors decide to try new innovations in their clinical work. Data were collected from 421 counseling staff from 71 outpatient treatment programs in 4 U.S. regions. Using hierarchical linear modeling, results reveal that the propensity to adopt workshop-based interventions is facilitated by two important mechanisms: (a) an innovative organization with creative leadership and (b) change-oriented staff attributes (i.e., seeking professional growth, efficacy, adaptability, and influence on others). Innovative leaders and a climate receptive to change also bolster the development of these change-oriented attributes. One implication of these findings is the cascading effect of leaders' support of innovative thinking and action resulting in employees strengthening their own adaptive skills and carrying this innovative thinking into individual adoption. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. The B P Deepwater Horizon disaster - why it shouldn't happen off Norway; Gulf of Mexico (GoM) oil spill

    Energy Technology Data Exchange (ETDEWEB)

    Stoichevski, William


    As Europe holidayed and the Gulf of Mexico (GoM) filled with oil from the blown Macondo well, Norway's Petroleum Inspection Authority (PSA) worked full tilt to bolster drilling safety with lessons from the Deepwater Horizon disaster. Known for approving the high-pressure, high-temperature wells of the Norwegian Sea, the PSA said it was already practicing 'all but five' of 21 new offshore safety recommendations from the office of US Secretary of the Interior Ken Salazar. Indeed, Salazar and the US President's press chief said out loud that America would look to the offshore safety model in Norway, where PSA inspectors horrified by Macondo were getting tougher on drilling and well design. Local oil spill planning was already on the right track. (Author)

  17. March of the living, a holocaust educational tour: effect on adolescent Jewish identity. (United States)

    Nager, Alan L; Pham, Phung; Gold, Jeffrey I


    March of the Living (MOTL) is a worldwide two-week trip for high school seniors to learn about the Holocaust by traveling to sites of concentration/death camps and Jewish historical sites in Poland and Israel. The mission statement of MOTL International states that participants will be able to "bolster their Jewish identity by acquainting them with the rich Jewish heritage in pre-war Eastern Europe." However, this claim has never been studied quantitatively. Therefore, 152 adolescents who participated in MOTL voluntarily completed an initial background questionnaire, a Jewish Identity Survey and a Global Domains Survey pre-MOTL, end-Poland and end-Israel. Results suggest that Jewish identity did not substantially increase overall or from one time period to the next.

  18. Practice stories in natural resource management continuing professional education: springboards for learning

    DEFF Research Database (Denmark)

    Stummann, Cathy Brown


    The use of stories from professional experience in continuing professional education has been on the rise in many fields, often aimed at bolstering capacity through sharing professional knowledge and/or supporting reflective practice. Practice stories are also suggested to be beneficial...... in supporting professional learning of new concepts. These uses of practice stories are not evident in public natural resource management (NRM) continuing professional education. In light of greater public involvement in NRM practice over the last 20 years, however, the use of practice stories could now...... be particularly beneficial to NRM professionals. This study examines the use of practice stories in workshops aimed at deepening public NRM professionals' understanding of social science concepts suggested to be valuable in making sense of the social and political complexity intertwined in public involvement...

  19. Social support and outcome of alcoholism treatment: an exploratory analysis. (United States)

    Booth, B M; Russell, D W; Soucek, S; Laughlin, P R


    Social support is becoming recognized as a positive influence on health and health maintenance. Forms of support which bolster the patient's sense of personal efficacy should enhance the alcoholic's ability to cope with a specific stressor (i.e., overcoming his or her addiction). Patients reporting higher levels of social support during alcoholism treatment, especially support that enhances his or her self-esteem, should therefore demonstrate improved outcome compared to patients with lower levels. Sixty-one consecutive admissions to an inpatient alcoholism treatment program at a rural midwestern medical center completed an assessment of six forms of social support (Guidance, Reliable Alliance, Reassurance of Worth, Opportunity for Nurturance, Attachment, and Social Integration) in terms of support obtained from family and friends and from the treatment environment. For each patient, additional information concerning age, marital status, financial support, and previous alcohol-related hospitalizations was also obtained. Outcome of treatment was measured by readmission for an alcohol-related diagnosis within 1 year of discharge. Survival analysis found that reassurance of worth from family and friends and number of previous hospitalizations were independent and significant predictors of time to readmission. Higher levels of reassurance of worth or esteem support significantly lengthened time to readmission, with the reverse relationship found for number of previous hospitalizations. These results suggest that specific sources (family and friends) and forms (reassurance of worth) of social support are important to the recovering alcoholic and that the effect of social support on treatment outcome is independent of the alcoholic's history of prior treatment failure. Interventions or program modifications should be designed specifically to bolster these facets of social support rather than addressing more general forms of support.

  20. The art of medicine: arts-based training in observation and mindfulness for fostering the empathic response in medical residents. (United States)

    Zazulak, Joyce; Sanaee, May; Frolic, Andrea; Knibb, Nicole; Tesluk, Eve; Hughes, Edward; Grierson, Lawrence E M


    Empathy is an essential attribute for medical professionals. Yet, evidence indicates that medical learners' empathy levels decline dramatically during medical school. Training in evidence-based observation and mindfulness has the potential to bolster the acquisition and demonstration of empathic behaviours for medical learners. In this prospective cohort study, we explore the impact of a course in arts-based visual literacy and mindfulness practice ( Art of Seeing ) on the empathic response of medical residents engaged in obstetrics and gynaecology and family medicine training. Following this multifaceted arts-based programme that integrates the facilitated viewing of art and dance, art-making, and mindfulness-based practices into a practitioner-patient context, 15 resident trainees completed the previously validated Interpersonal Reactivity Index, Compassion, and Mindfulness Scales. Fourteen participants also participated in semistructured interviews that probed their perceived impacts of the programme on their empathic clinical practice. The results indicated that programme participants improved in the Mindfulness Scale domains related to self-confidence and communication relative to a group of control participants following the arts-based programme. However, the majority of the psychometric measures did not reveal differences between groups over the duration of the programme. Importantly, thematic qualitative analysis of the interview data revealed that the programme had a positive impact on the participants' perceived empathy towards colleagues and patients and on the perception of personal and professional well-being. The study concludes that a multifaceted arts-based curriculum focusing on evidence-based observation and mindfulness is a useful tool in bolstering the empathic response, improving communication, and fostering professional well-being among medical residents. Published by the BMJ Publishing Group Limited. For permission to use (where not already

  1. Laboratory Astronomy Needs for the Study of Dust in Comets in the Next Decade (United States)

    Lisse, Carey M.


    The Spitzer Space Telescope observed the mid-IR ( 5-40 µm) spectra of ejecta from the hypervelocity impact of the Deep Impact projectile with comet 9P/Tempel-1. Spectral modeling demonstrates that there are abundant minerals present in the ejecta including Ca/Fe/Mg-rich silicates, carbonates, phyllosilicates, water ice, amorphous carbon, and sulfides (Lisse et al. 2006). Other Infrared Space Observatory (ISO), Spitzer, and Akari observations provide evidence for large reservoirs of these dusty species not only in comets, but in related reservoirs: Centaurs, Kuiper Belt objects, and exo-solar Kuiper Belts. In the next 5 years, we can expect SOFIA, ASTRO-H and JWST measurements to build on these results in the mid-IR. Consistency with STARDUST sample return findings has bolstered confidence in these remote sensing results (Flynn et al. 2008). However, precise mineralogical identifications are hampered by the lack of detailed spectral measurements, particularly of transmission and of the associated derived absorption coefficient, for astrophysically relevant materials in the 3 - 40 µm range over which Spitzer, etc. sensitive. The upcoming Herschel Space Observatory mission will open up a new wavelength range, collecting mineralogically-characteristic far-IR emission spectra of comet dust populations in the range of 57 - 210 µm using its Photodetector Array Camera and Spectrometer (PACS), and out to 650 um using its Spectral and Photometric Imaging Receiver (SPIRE). Many astrophysically important minerals (e.g., pyroxenes, carbonates, phyllosilicates, water ice) have potentially distinctive, but poorly quantified, PACS-range emission features that are sensitive to chemical composition and crystal structure. Mineral identifications have often been based on a single strong mid-IR feature lack confidence [Molster & Waters 2003], which can be bolstered by measuring multiple complementary far-IR features. Full laboratory spectroscopic knowledge of candidate materials, as

  2. The Australian Hydrogen and Fuel Cells Education Program

    International Nuclear Information System (INIS)

    Luigi Bonadio


    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  3. The Australian Hydrogen and Fuel Cells Education Program

    Energy Technology Data Exchange (ETDEWEB)

    Luigi Bonadio [Senior Consultant Luigi Bonadio and Associates (Australia)


    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  4. Identifying Policy Implications and Future Research Directions Regarding Military Community Support and Child Psychosocial Adjustment. (United States)

    Conforte, Allison M; DeLeon, Patrick H; Engel, Charles C; Ling, Catherine; Bakalar, Jennifer L; Tanofsky-Kraff, Marian


    As former U.S. Army Surgeon General Horoho points out, a large fraction of what determines the health and readiness of our military families does not occur during appointments with professionals, but rather within the "Lifespace-where health really happens...." Indeed, when children of military families experience psychosocial difficulties, such stress impacts the service members' personal well-being and ability to focus at work, impairing their capacity to attend to the mission. As such, the Department of Defense (DoD) has instituted a family readiness system to bolster resiliency within military families, including children, e.g., by linking families with support networks. Bolstering military family resiliency, including the prevention of and effective intervention for child psychosocial problems, is an important issue at all levels of the DoD. Service members, leaders, and policy makers have a vested interest in promoting mission readiness and a healthy force. Research can play an important role in shaping decision-making by consolidating what is currently known and not known about a particular expertise area. To date, there has been no consolidation of research regarding outcomes associated with military community support and the programs that currently exist to bolster child and family resiliency. Given the importance of military families to mission readiness, a review of the relevant research is warranted. This commentary article reviews the literature on community support for military children, provides an overview of currently available resources, discusses concerns with the current provision of support services to military families, and offers recommendations for future research, policy, and implementation of military community support programs. Although there is a dearth of research on available support programs, there appears to be no lack of services available to military families. However, several steps could be taken to make these resources into a

  5. Variability of ischiofemoral space dimensions with changes in hip flexion: an MRI study

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Adam C.; Howe, Benjamin M. [Mayo Clinic College of Medicine, Department of Radiology, Rochester, MN (United States); Hollman, John H.; Finnoff, Jonathan T. [Mayo Clinic College of Medicine, Department of Physical Medicine and Rehabilitation, Rochester, MN (United States)


    The primary aim of this study was to determine if ischiofemoral space (IFS) dimensions vary with changes in hip flexion as a result of placing a bolster behind the knees during magnetic resonance imaging (MRI). A secondary aim was to determine if IFS dimensions vary between supine and prone hip neutral positions. The study employed a prospective design. Sports medicine center within a tertiary care institution. Five male and five female adult subjects (age mean = 29.2, range = 23-35; body mass index [BMI] mean = 23.5, range = 19.5-26.6) were recruited to participate in the study. An axial, T1-weighted MRI sequence of the pelvis was obtained of each subject in a supine position with their hips in neutral and flexed positions, and in a prone position with their hips in neutral position. Supine hip flexion was induced by placing a standard, 9-cm-diameter MRI knee bolster under the subject's knees. The order of image acquisition (supine hip neutral, supine hip flexed, prone hip neutral) was randomized. The IFS dimensions were then measured on a separate workstation. The investigator performing the IFS measurements was blinded to the subject position for each image. The main outcome measurements were the IFS dimensions acquired with MRI. The mean IFS dimensions in the prone position were 28.25 mm (SD 5.91 mm, standard error mean 1.32 mm). In the supine hip neutral position, the IFS dimensions were 25.1 (SD 5.6) mm. The mean difference between the two positions of 3.15 (3.6) mm was statistically significant (95 % CI of the difference = 1.4 to 4.8 mm, t{sub 19} = 3.911, p =.001). The mean IFS dimensions in the hip flexed position were 36.9 (SD 5.7) mm. The mean difference between the two supine positions of 11.8 (4.1) mm was statistically significant (95 % CI of the difference = 9.9 to 13.7 mm, t{sub 19} = 12.716, p <.001). Our findings demonstrate that the IFS measurements obtained with MRI are dependent upon patient positioning with respect to hip flexion and

  6. The gender division of labor and the reproduction of female disadvantage: toward an integrated theory. (United States)

    Chafetz, J S


    A theory of the major mechanisms that sustain and reproduce systems of gender stratification is presented. The central support mechanism is the gender division of labor within both the family and the wider society. This gender division of labor and superior male power continuously bolster each other. Men can use their power, individually at the micro level and collectively at the macro, to allocate work roles and to create social and interpersonal definitions that justify their superior position, their behavior, and the treatment of females. In this way, they individually and collectively coerce women into behaviors and roles that perpetuate their subordinate status. Yet except for occasional times of women's movement activism, most women do not feel coerced, and most members of both genders do not consciously perceive the system as fundamentally inequitable. Indeed, women are likely to feel that they have chosen the lives they lead as freely as have men. This results from the various processes that contribute to the production of gender differentiation, by which both males and females come to want to behave in gender normative ways. The author does not blame the victim or argue that women choose their subordinate status. Instead, her theory suggests that in the absence of gender differentiation and gender-normative choices, women would nonetheless be constrained to perform the work that more powerful men delegate to them. To the extent women perceive that they choose the roles they play, the system of gender stratification is substantially bolstered because of its apparent legitimacy. Most women do not feel that their domestic and childrearing responsibilities, and therefore a heavy double workday, result from male power. Rather, they define them as their natural, God-given or desired labors. Under such circumstances, male power is only potential; it need not be employed. When the women's movement alerts some women to the coercive aspects of the process, system

  7. Effects of Terrestrial Buffer Zones on Amphibians on Golf Courses (United States)

    Puglis, Holly J.; Boone, Michelle D.


    A major cause of amphibian declines worldwide is habitat destruction or alteration. Public green spaces, such as golf courses and parks, could serve as safe havens to curb the effects of habitat loss if managed in ways to bolster local amphibian communities. We reared larval Blanchard's cricket frogs (Acris blanchardi) and green frogs (Rana clamitans) in golf course ponds with and without 1 m terrestrial buffer zones, and released marked cricket frog metamorphs at the golf course ponds they were reared in. Larval survival of both species was affected by the presence of a buffer zone, with increased survival for cricket frogs and decreased survival for green frogs when reared in ponds with buffer zones. No marked cricket frog juveniles were recovered at any golf course pond in the following year, suggesting that most animals died or migrated. In a separate study, we released cricket frogs in a terrestrial pen and allowed them to choose between mown and unmown grass. Cricket frogs had a greater probability of using unmown versus mown grass. Our results suggest that incorporating buffer zones around ponds can offer suitable habitat for some amphibian species and can improve the quality of the aquatic environment for some sensitive local amphibians. PMID:22761833

  8. Patterns and biases in climate change research on amphibians and reptiles: a systematic review (United States)


    Climate change probably has severe impacts on animal populations, but demonstrating a causal link can be difficult because of potential influences by additional factors. Assessing global impacts of climate change effects may also be hampered by narrow taxonomic and geographical research foci. We review studies on the effects of climate change on populations of amphibians and reptiles to assess climate change effects and potential biases associated with the body of work that has been conducted within the last decade. We use data from 104 studies regarding the effect of climate on 313 species, from 464 species–study combinations. Climate change effects were reported in 65% of studies. Climate change was identified as causing population declines or range restrictions in half of the cases. The probability of identifying an effect of climate change varied among regions, taxa and research methods. Climatic effects were equally prevalent in studies exclusively investigating climate factors (more than 50% of studies) and in studies including additional factors, thus bolstering confidence in the results of studies exclusively examining effects of climate change. Our analyses reveal biases with respect to geography, taxonomy and research question, making global conclusions impossible. Additional research should focus on under-represented regions, taxa and questions. Conservation and climate policy should consider the documented harm climate change causes reptiles and amphibians. PMID:27703684

  9. Biogas energy from family-sized digesters in Uganda: Critical factors and policy implications

    International Nuclear Information System (INIS)

    Walekhwa, Peter N.; Mugisha, Johnny; Drake, Lars


    Dependence on fossil energy sources is increasingly becoming unsustainable due to ecological and environmental problems and rapid depletion. Biogas energy could augment these conventional energy sources but despite its advantages and favourable conditions for its production, biogas energy use in Uganda remains low due to technical, economic and socio-cultural impediments. Based on primary data on households in Central and Eastern Uganda and the use of logistic regression, this study analyses factors affecting the adoption of biogas energy in Uganda. The empirical results suggest that the probability of a household adopting biogas technology increases with decreasing age of head of household, increasing household income, increasing number of cattle owned, increasing household size, male head of household and increasing cost of traditional fuels. In contrast, the likelihood of adoption decreases with increasing remoteness of household location and increasing household land area. Policy options and recommendations including educational and awareness campaigns on biogas benefits and successes, the provision of financial and non-financial incentives to households and establishment of an institutional framework could bolster wider biogas energy acceptance in Uganda.

  10. Golden Jubilee Photos: Four giants break new ground

    CERN Multimedia


    The four LHC experiments are on an unprecedented scale. The detectors will record particle collisions far more powerful than those at any other particle accelerator. One of the detectors, ATLAS, will be the largest-volume particle detector ever, a cylinder 45 metres long and 25 metres high. And the collaborations are a step beyond LHC's predecessor, LEP, involving even more people from more countries. Together, these four experiments promise to open a door to new realms of physics. CMS and ATLAS are both general-purpose detectors, whose major quarry include the Higgs particle, which could give other particles their mass, and supersymmetric particles, which would bolster theories beyond the Standard Model. A major technical challenge for CMS has been acquiring 61 000 large, precision-grown crystals, denser than iron, for catching high-energy photons and electrons (1st bottom photo). ATLAS includes the world's largest superconducting magnets (2nd bottom photo), eight coils arranged into a large barrel shape t...

  11. Self-Affirmation Theory and Performance Feedback: When Scoring High Makes You Feel Low. (United States)

    Velez, John A; Hanus, Michael D


    Video games have a wide variety of benefits for players. The current study examines how video games can also increase players' willingness to internalize important but threatening self-information. Research suggests that negative information regarding a valued self-image evokes defensive strategies aimed at dismissing or discrediting the source of information. Self-Affirmation Theory proposes that affirming or bolstering an important self-image unrelated to the previous threat can be an effective strategy for reducing defensiveness. Participants in the current study completed a fictitious intelligence test and received negative or no feedback, followed by 15 minutes of video game play that resulted in positive or no feedback. Results suggest that participants who valued video game success as part of their identity exhibited less defensive strategies in the form of increased test credibility ratings and lower self-perceptions of intelligence. This suggests that performing well on a video game is an affirmational resource for players whose identities are contingent upon such success. However, results also indicate that players who did not value video game success but received positive video game feedback exhibited more defensive reactions to the negative intelligence test feedback. This suggests that while players who value video game success as part of their identity may reap benefits from video game play after a self-threat, those who do not value such success may experience more harmful effects.

  12. Evaluation of Marine Microalga Diacronema vlkianum Biomass Fatty Acid Assimilation in Wistar Rats

    Directory of Open Access Journals (Sweden)

    Cristina de Mello-Sampayo


    Full Text Available Diacronema vlkianum is a marine microalgae for which supposed health promoting effects have been claimed based on its phytochemical composition. The potential use of its biomass as health ingredient, including detox-shakes, and the lack of bioavailability studies were the main concerns. In order to evaluate the microalgae-biomass assimilation and its health-benefits, single-dose (CD1-mice studies were followed by 66-days repeated-dose study in Wistar rats with the highest tested single-dose of microalgae equivalent to 101 mg/kg eicosapentaenoic acid + docosahexaenoic acid (EPA+DHA. Microalgae-supplementation modulated EPA and docosapentaenoic acid enrichment at arachidonic acid content expenditure in erythrocytes and liver, while increasing EPA content of heart and adipose tissues of rats. Those fatty acid (FA changes confirmed the D. vlkianum-biomass FA assimilation. The principal component analyses discriminated brain from other tissues, which formed two other groups (erythrocytes, liver, and heart separated from kidney and adipose tissues, pointing to a distinct signature of FA deposition for the brain and for the other organs. The improved serum lipid profile, omega-3 index and erythrocyte plasticity support the cardiovascular benefits of D. vlkianum. These results bolster the potential of D. vlkianum-biomass to become a “heart-healthy” food supplement providing a safe and renewable source of bioavailable omega-3 FA.

  13. A labor perspective of workplace violence prevention. Identifying research needs. (United States)

    Rosen, J


    During the past decade, labor unions have contributed to efforts to increase awareness of the importance of workplace violence as an occupational hazard. Research by the National Institute for Occupational Safety and Health and the U.S. Department of Justice have bolstered these efforts. This research revealed that workplace violence is the second leading cause of traumatic-injury death on the job for men, the leading cause of traumatic-injury death on the job for women, and accounts for some 2 million nonfatal injuries each year in the United States. Ten years ago, the debate focused on whether workplace violence is an occupational hazard or strictly a police and criminal justice issue. Labor unions have joined with occupational safety and health professionals in recognizing that workplace violence is a serious occupational hazard that is often predictable and preventable. They have advocated that employers establish multidimensional violence-prevention programs. Although the nature of workplace violence varies from industry to industry, implementation of the federal Occupational Safety and Health Administration (OSHA) Violence Prevention Guidelines for Health Care and Social Service Workers and for Late-Night Retail Establishments is a high priority to unions in the affected industries. Labor wants employers to invest in protecting workers from violence through voluntary programs and state legislation, and it supports the promulgation of a mandatory federal OSHA standard. To that end, intervention research can play a key role in demonstrating effective, technically and economically feasible prevention strategies

  14. “Recovering our Stories”: A Small Act of Resistance

    Directory of Open Access Journals (Sweden)

    Lucy Costa


    Full Text Available This paper describes a community event organized in response to the appropriation and overreliance on the psychiatric patient “personal story” within mental health organizations. The sharing of experiences through stories by individuals who self-identify as having “lived experience” has been central to the history of organizing for change in and outside of the psychiatric system. However, in the last decade, personal stories have increasingly been used by the psychiatric system to bolster research, education, and fundraising interests. We explore how personal stories from consumer/survivors have been harnessed by mental health organizations to further their interests and in so doing have shifted these narrations from “agents of change” towards one of “disability tourism” or “patient porn.” We mark the ethical dilemmas of narrative cooptation and consumption, and query how stories of resistance can be reclaimed not as personal recovery narratives but rather as a tool for socio-political change.

  15. Computational Biology and Bioinformatics in Nigeria (United States)

    Fatumo, Segun A.; Adoga, Moses P.; Ojo, Opeolu O.; Oluwagbemi, Olugbenga; Adeoye, Tolulope; Ewejobi, Itunuoluwa; Adebiyi, Marion; Adebiyi, Ezekiel; Bewaji, Clement; Nashiru, Oyekanmi


    Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into useful knowledge has caused bioinformatics to gain prominence and importance. Bioinformatics is an interdisciplinary research area that applies techniques, methodologies, and tools in computer and information science to solve biological problems. In Nigeria, bioinformatics has recently played a vital role in the advancement of biological sciences. As a developing country, the importance of bioinformatics is rapidly gaining acceptance, and bioinformatics groups comprised of biologists, computer scientists, and computer engineers are being constituted at Nigerian universities and research institutes. In this article, we present an overview of bioinformatics education and research in Nigeria. We also discuss professional societies and academic and research institutions that play central roles in advancing the discipline in Nigeria. Finally, we propose strategies that can bolster bioinformatics education and support from policy makers in Nigeria, with potential positive implications for other developing countries. PMID:24763310

  16. The Neuropsychology of Traumatic Brain Injury: Looking Back, Peering Ahead. (United States)

    Yeates, Keith Owen; Levin, Harvey S; Ponsford, Jennie


    The past 50 years have been a period of exciting progress in neuropsychological research on traumatic brain injury (TBI). Neuropsychologists and neuropsychological testing have played a critical role in these advances. This study looks back at three major scientific advances in research on TBI that have been critical in pushing the field forward over the past several decades: The advent of modern neuroimaging; the recognition of the importance of non-injury factors in determining recovery from TBI; and the growth of cognitive rehabilitation. Thanks to these advances, we now have a better understanding of the pathophysiology of TBI and how recovery from the injury is also shaped by pre-injury, comorbid, and contextual factors, and we also have increasing evidence that active interventions, including cognitive rehabilitation, can help to promote better outcomes. The study also peers ahead to discern two important directions that seem destined to influence research on TBI over the next 50 years: the development of large, multi-site observational studies and randomized controlled trials, bolstered by international research consortia and the adoption of common data elements; and attempts to translate research into health care and health policy by the application of rigorous methods drawn from implementation science. Future research shaped by these trends should provide critical evidence regarding the outcomes of TBI and its treatment, and should help to disseminate and implement the knowledge gained from research to the betterment of the quality of life of persons with TBI. (JINS, 2017, 23, 806-817).

  17. Mothers' use of blogs while engaged in family-based treatment for a child's eating disorder. (United States)

    LaMarre, Andrea; Robson, Jane; Dawczyk, Anna


    We explore parents' use of blogs while engaged in family-based treatment (FBT), a form of treatment in which parents engage as the primary givers of care for a child's eating disorder. We sought to bring together emergent literature on the value of blogging for social support with a body of literature on caregiving for a child with an eating disorder and to understand how parents use blogs while engaged in FBT. We conducted a thematic analysis of 138 blog entries written by 5 mothers. Two main themes emerged: the importance of support and shifts in parenting. Blogs detailed how parents actively seek to meet their needs during a difficult time using online interactions to bolster sources of support that exist offline. This intensive form of treatment also provoked shifts in parenting, which parents described on their blogs. Parents' blogs were rich with descriptions of their use of mutually reinforcing on- and offline support. The unique context of the blogs allowed for access to data that were not generated for the purpose of research. Results add to the growing body of literature about parents' caregiving experiences and use of blogs for social support, and they offer implications for using online spaces as adjunct support for families. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  18. Add-on Effects of Repetitive Transcranial Magnetic Stimulation on Subacute Aphasia Therapy: Enhanced Improvement of Functional Communication and Basic Linguistic Skills. A Randomized Controlled Study. (United States)

    Rubi-Fessen, Ilona; Hartmann, Alexander; Huber, Walter; Fimm, Bruno; Rommel, Thomas; Thiel, Alexander; Heiss, Wolf-Dieter


    To determine to what extent repetitive transcranial magnetic stimulation (rTMS) combined with speech and language therapy improves functional communication and basic linguistic skills of individuals with subacute aphasia. Randomized, blinded, and sham-controlled study. Neurologic rehabilitation hospital. Participants (N=30) with subacute aphasia after stroke. During a 2-week treatment period, half of the participants received 10 sessions of 20-minute inhibitory 1-Hz rTMS over the right inferior frontal gyrus (Brodmann area 45), and the other half received sham stimulation. Directly thereafter, all the participants underwent 45 minutes of speech and language therapy. Aachen Aphasia Test, Amsterdam-Nijmegen Everyday Language Test (ANELT), a naming screening, and subscales of the FIM, all assessed the day before and the day after treatment period. The participants who received real rTMS significantly improved with respect to all 10 measures of basic linguistic skills and functional communication, whereas sham-treated participants significantly improved in only 6 of 10 measures (paired t tests, Pcommunication (ANELT) (repeated-measures analysis of variance, P≤.05). For the first time, this study has demonstrated that basic linguistic skills as well as functional communication are bolstered by combining rTMS and behavioral language therapy in patients with subacute aphasia. Copyright © 2015 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  19. A novel function for the IκB inhibitor Cactus in promoting Dorsal nuclear localization and activity in the Drosophila embryo. (United States)

    Cardoso, Maira Arruda; Fontenele, Marcio; Lim, Bomyi; Bisch, Paulo Mascarello; Shvartsman, Stanislav Y; Araujo, Helena Marcolla


    The evolutionarily conserved Toll signaling pathway controls innate immunity across phyla and embryonic patterning in insects. In the Drosophila embryo, Toll is required to establish gene expression domains along the dorsal-ventral axis. Pathway activation induces degradation of the IκB inhibitor Cactus, resulting in a ventral-to-dorsal nuclear gradient of the NFκB effector Dorsal. Here, we investigate how cactus modulates Toll signals through its effects on the Dorsal gradient and on Dorsal target genes. Quantitative analysis using a series of loss- and gain-of-function conditions shows that the ventral and lateral aspects of the Dorsal gradient can behave differently with respect to Cactus fluctuations. In lateral and dorsal embryo domains, loss of Cactus allows more Dorsal to translocate to the nucleus. Unexpectedly, cactus loss-of-function alleles decrease Dorsal nuclear localization ventrally, where Toll signals are high. Overexpression analysis suggests that this ability of Cactus to enhance Toll stems from the mobilization of a free Cactus pool induced by the Calpain A protease. These results indicate that Cactus acts to bolster Dorsal activation, in addition to its role as a NFκB inhibitor, ensuring a correct response to Toll signals. © 2017. Published by The Company of Biologists Ltd.

  20. Development of a data mining and imaging informatics display tool for a multiple sclerosis e-folder system (United States)

    Liu, Margaret; Loo, Jerry; Ma, Kevin; Liu, Brent


    Multiple sclerosis (MS) is a debilitating autoimmune disease of the central nervous system that damages axonal pathways through inflammation and demyelination. In order to address the need for a centralized application to manage and study MS patients, the MS e-Folder - a web-based, disease-specific electronic medical record system - was developed. The e-Folder has a PHP and MySQL based graphical user interface (GUI) that can serve as both a tool for clinician decision support and a data mining tool for researchers. This web-based GUI gives the e-Folder a user friendly interface that can be securely accessed through the internet and requires minimal software installation on the client side. The e-Folder GUI displays and queries patient medical records--including demographic data, social history, past medical history, and past MS history. In addition, DICOM format imaging data, and computer aided detection (CAD) results from a lesion load algorithm are also displayed. The GUI interface is dynamic and allows manipulation of the DICOM images, such as zoom, pan, and scrolling, and the ability to rotate 3D images. Given the complexity of clinical management and the need to bolster research in MS, the MS e-Folder system will improve patient care and provide MS researchers with a function-rich patient data hub.

  1. Angiosperm leaf vein evolution was physiologically and environmentally transformative. (United States)

    Boyce, C Kevin; Brodribb, Tim J; Feild, Taylor S; Zwieniecki, Maciej A


    The veins that irrigate leaves during photosynthesis are demonstrated to be strikingly more abundant in flowering plants than in any other vascular plant lineage. Angiosperm vein densities average 8 mm of vein per mm(2) of leaf area and can reach 25 mm mm(-2), whereas such high densities are absent from all other plants, living or extinct. Leaves of non-angiosperms have consistently averaged close to 2 mm mm(-2) throughout 380 million years of evolution despite a complex history that has involved four or more independent origins of laminate leaves with many veins and dramatic changes in climate and atmospheric composition. We further demonstrate that the high leaf vein densities unique to the angiosperms enable unparalleled transpiration rates, extending previous work indicating a strong correlation between vein density and assimilation rates. Because vein density is directly measurable in fossils, these correlations provide new access to the physiology of extinct plants and how they may have impacted their environments. First, the high assimilation rates currently confined to the angiosperms among living plants are likely to have been unique throughout evolutionary history. Second, the transpiration-driven recycling of water that is important for bolstering precipitation in modern tropical rainforests might have been significantly less in a world before the angiosperms.

  2. Sex differences in preferences for humor: a replication, modification, and extension. (United States)

    Hone, Liana S E; Hurwitz, William; Lieberman, Debra


    Evolutionary-minded scientists have proposed that humor is a sexually selected trait in men that signals mate quality. Indeed, women tend to prefer men who make them laugh and men tend to prefer women who laugh at their jokes. However, it is unclear how robust this pattern is. Here we report a replication of one of the first studies (Bressler, Martin, and Balshine, 2006) to examine the sex differences in preferences for humor receptivity versus humor production. We replicate Bressler et al.'s (2006) findings that men prefer women who are receptive to their humor whereas women prefer men who produce humor. These findings held even after we modified Bressler et al.'s questionnaire for better conceptual validity. Furthermore, using a separate measure designed to assess trade-offs, we found that men viewed humor receptivity as a necessity and humor production as a luxury when they were asked to create an ideal long-term partner. For women, it was just the opposite. These results bolster the claim that sexual selection has shaped sex differences regarding preferences for a prospective mate's sense of humor and that what one means by "sense of humor" can vary.

  3. Monte Carlo Modeling the UCN τ Magneto-Gravitational Trap (United States)

    Holley, A. T.; UCNτ Collaboration


    The current uncertainty in our knowledge of the free neutron lifetime is dominated by the nearly 4 σ discrepancy between complementary ``beam'' and ``bottle'' measurement techniques. An incomplete assessment of systematic effects is the most likely explanation for this difference and must be addressed in order to realize the potential of both approaches. The UCN τ collaboration has constructed a large-volume magneto-gravitational trap that eliminates the material interactions which complicated the interpretation of previous bottle experiments. This is accomplished using permanent NdFeB magnets in a bowl-shaped Halbach array to confine polarized UCN from the sides and below and the earth's gravitational field to trap them from above. New in situ detectors that count surviving UCN provide a means of empirically assessing residual systematic effects. The interpretation of that data, and its implication for experimental configurations with enhanced precision, can be bolstered by Monte Carlo models of the current experiment which provide the capability for stable tracking of trapped UCN and detailed modeling of their polarization. Work to develop such models and their comparison with data acquired during our first extensive set of systematics studies will be discussed.

  4. Mutualism Disruption Threatens Global Plant Biodiversity: A Systematic Review.

    Directory of Open Access Journals (Sweden)

    Clare E Aslan

    Full Text Available As global environmental change accelerates, biodiversity losses can disrupt interspecific interactions. Extinctions of mutualist partners can create "widow" species, which may face reduced ecological fitness. Hypothetically, such mutualism disruptions could have cascading effects on biodiversity by causing additional species coextinctions. However, the scope of this problem - the magnitude of biodiversity that may lose mutualist partners and the consequences of these losses - remains unknown.We conducted a systematic review and synthesis of data from a broad range of sources to estimate the threat posed by vertebrate extinctions to the global biodiversity of vertebrate-dispersed and -pollinated plants. Though enormous research gaps persist, our analysis identified Africa, Asia, the Caribbean, and global oceanic islands as geographic regions at particular risk of disruption of these mutualisms; within these regions, percentages of plant species likely affected range from 2.1-4.5%. Widowed plants are likely to experience reproductive declines of 40-58%, potentially threatening their persistence in the context of other global change stresses.Our systematic approach demonstrates that thousands of species may be impacted by disruption in one class of mutualisms, but extinctions will likely disrupt other mutualisms, as well. Although uncertainty is high, there is evidence that mutualism disruption directly threatens significant biodiversity in some geographic regions. Conservation measures with explicit focus on mutualistic functions could be necessary to bolster populations of widowed species and maintain ecosystem functions.

  5. Playing Music for a Smarter Ear: Cognitive, Perceptual and Neurobiological Evidence (United States)

    Strait, Dana; Kraus, Nina


    Human hearing depends on a combination of cognitive and sensory processes that function by means of an interactive circuitry of bottom-up and top-down neural pathways, extending from the cochlea to the cortex and back again. Given that similar neural pathways are recruited to process sounds related to both music and language, it is not surprising that the auditory expertise gained over years of consistent music practice fine-tunes the human auditory system in a comprehensive fashion, strengthening neurobiological and cognitive underpinnings of both music and speech processing. In this review we argue not only that common neural mechanisms for speech and music exist, but that experience in music leads to enhancements in sensory and cognitive contributors to speech processing. Of specific interest is the potential for music training to bolster neural mechanisms that undergird language-related skills, such as reading and hearing speech in background noise, which are critical to academic progress, emotional health, and vocational success. PMID:22993456

  6. Disordered eating behavior and mental health correlates among treatment seeking obese women. (United States)

    Altamura, M; Rossi, G; Aquilano, P; De Fazio, P; Segura-Garcia, C; Rossetti, M; Petrone, A; Lo Russo, T; Vendemiale, G; Bellomo, A


    Previous research has suggest that obesity is associated with increased risk for psychopathological disorders, however, little is known about which obese patients are most vulnerable to psychopathological disorders. We therefore investigated 126 treatment-seeking obese women to describe eating disorder pathology and mental health correlates, and to identify disordered eating behaviors that may place obese at increased risk for psychopathological disorders. The Structured Clinical Interview for DSM-IV (SCID) was used to identify Eating Disorders (ED). A battery of psychological tests, including the Anxiety Scale Questionnaire (ASQ,) Clinical Depression Questionnaire (CDQ), Eating Disorder Inventory-2 (EDI-2) Eating Attitudes Test-26 (EAT-26) scales and structured clinical interview were administered to all the patients. We analyzed the link between psychopathological disorders and eating attitudes by using both multiple regression analysis and non-parametric correlation. Disordered eating behaviors and emotional behavioral aspects related to Anorexia Nervosa, such as ineffectiveness, are strongly linked to the depression and anxiety in obese subjects. No correlation was found between psychopathological disorders and age or anthropometric measurements. Findings corroborate earlier work indicating that psychological distress is elevated in obese treatment seeking, bolstering the need for mental health assessment of such individuals. The feeling of ineffectiveness constitutes the major predictor of psychopathological aspects. This is an important result which may inform the development of effective interventions for obese patients and prevention of psychopathological disorders.

  7. The effects of parental mental health and social-emotional coping on adolescent eating disorder attitudes and behaviors. (United States)

    Martinson, Laura E; Esposito-Smythers, Christianne; Blalock, Dan V


    This study examined whether social-emotional coping skills moderate the association between parental mental health symptoms and adolescent disordered eating attitudes and behaviors in a clinical sample of adolescents with internalizing and/or externalizing symptoms. Fifty-nine adolescent-parent dyads (N = 118 total participants) recruited from a metropolitan area in the Northeastern United States completed assessments at baseline and 12-month follow-up. Generally, higher parental depression and anxiety were only found to be associated with greater disordered eating attitudes and behaviors among adolescents who reported poorer (versus stronger) emotional awareness/expression skills and less (versus greater) ability to regulate emotions. Results may suggest that adolescents who lack the ability to effectively recognize, express, and manage negative emotions that arise in the context of a challenging home environment may be at greater risk for engaging in maladaptive coping behaviors, such as disordered eating. Thus, bolstering adolescent social-emotional coping skills may help protect against adolescent disordered eating. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  8. Garnet Yield Strength at High Pressures and Implications for Upper Mantle and Transition Zone Rheology

    International Nuclear Information System (INIS)

    Kavner, A.


    Garnet helps control the mechanical behavior of the Earth's crust, mantle, and transition zone. Here, measurements are presented suggesting that garnet, long considered to be a high-viscosity phase, is actually weaker than the other dominant components in the transition zone. The mechanical behavior of garnet at high pressures was examined using radial diffraction techniques in the diamond anvil cell. The yield strength of grossular garnet was inferred from synchrotron X-ray measurements of differential lattice strains. The differential stress was found to increase from 1.3 (±0.6) GPa at a hydrostatic pressure 5.8 (±1.1) GPa to 4.1 (±0.4) GPa at 15.7 (±1.0) GPa, where it was level to 19 GPa. The strength results are consistent with inferred strength values for majorite garnet from measurements in the diamond cell normal geometry, bolstering the idea that garnet-structured materials may all have similar strengths. In this low-temperature, high differential stress regime, garnet is shown to be significantly weaker than anhydrous ringwoodite and to have a strength similar to hydrous ringwoodite. This result suggests that the presence of water in the transition zone may not be required to explain a weak rheology, and therefore models of transition zone behavior built assuming that garnet is the high-strength phase may need to be revised.

  9. The evolution of the federal funding policies for the public health surveillance component of Brazil's Unified Health System (SUS

    Directory of Open Access Journals (Sweden)

    Vitor Laerte Pinto Junior


    Full Text Available Health surveillance (HS is one of the key components of the Brazilian Unified Health System (SUS. This article describes recent changes in health surveillance funding models and the role these changes have had in the reorganization and decentralization of health actions. Federal law no. 8.080 of 1990 defined health surveillance as a fundamental pillar of the SUS, and an exclusive fund with equitable distribution criteria was created in the Basic Operational Norm of 1996 to pay for health surveillance actions. This step facilitated the decentralization of health care at the municipal level, giving local authorities autonomy to plan and provide services. The Health Pact of 2006 and its regulation under federal decree No. 3252 in 2009 bolstered the processes of decentralization, regionalization and integration of health care. Further changes in the basic concepts of health surveillance around the world and in the funding policies negotiated by different spheres of government in Brazil have been catalysts for the process of HS institutionalization in recent years.

  10. Mandates for Collaboration: Health Care and Child Welfare Policy and Practice Reforms Create the Platform for Improved Health for Children in Foster Care. (United States)

    Zlotnik, Sarah; Wilson, Leigh; Scribano, Philip; Wood, Joanne N; Noonan, Kathleen


    Improving the health of children in foster care requires close collaboration between pediatrics and the child welfare system. Propelled by recent health care and child welfare policy reforms, there is a strong foundation for more accountable, collaborative models of care. Over the last 2 decades health care reforms have driven greater accountability in outcomes, access to care, and integrated services for children in foster care. Concurrently, changes in child welfare legislation have expanded the responsibility of child welfare agencies in ensuring child health. Bolstered by federal legislation, numerous jurisdictions are developing innovative cross-system workforce and payment strategies to improve health care delivery and health care outcomes for children in foster care, including: (1) hiring child welfare medical directors, (2) embedding nurses in child welfare agencies, (3) establishing specialized health care clinics, and (4) developing tailored child welfare managed care organizations. As pediatricians engage in cross-system efforts, they should keep in mind the following common elements to enhance their impact: embed staff with health expertise within child welfare settings, identify long-term sustainable funding mechanisms, and implement models for effective information sharing. Now is an opportune time for pediatricians to help strengthen health care provision for children involved with child welfare. Copyright © 2015. Published by Elsevier Inc.

  11. The United Nations Population Fund and Planned Parenthood proudly present the International Conference on Population and Development. (United States)

    Corey, W


    The 1994 International Conference on Population and Development (ICPD) was orchestrated and largely controlled by such pro-choice groups as the UN Population Fund, Planned Parenthood, and radical American feminists. Efforts to promote abortion in parts of the world where it is illegal were couched in such terms as "safe motherhood" and "reproductive health." These efforts failed, however, with inclusion of the clause stating that abortion shall not be promoted as a means of family planning. However, the seeds of abortion, in the form of unnatural contraception, continue to be spread throughout the world. On the other hand, in the nongovernmental organization forum, which ran concurrently with the ICPD, pro-life organizations attracted a great deal of attention at the International Right to Life Federation booth. A workshop on natural family planning was attended by only a few people, but interest was high and the attendees followed-up by requesting more information during the Forum. A press conference held by Catholics for a Free Choice backfired because the mostly Moslem audience left angry at the women's apparent lack of obedience to the Pope. Other American feminists were confronted with the sight of women from the Third World picketing the conference with signs like "2 cars for every family in the North; one child for every family in the South." The pro-choice activists succeeded in bolstering the esteem of the Pope by making it evident that he is carrying the burden of family values almost singlehandedly.

  12. Do organisms have an ontological status? (United States)

    Wolfe, Charles T


    The category "organism" has an ambiguous status: is it scientific or is it philosophical? Or, if one looks at it from within the relatively recent field or sub-field of philosophy of biology, is it a central, or at least legitimate category therein, or should it be dispensed with? In any case, it has long served as a kind of scientific bolstering for a philosophical train of argument which seeks to refute the mechanistic or reductionist trend, which has been perceived as dominant since the 17th century, whether in the case of Stahlian animism, Leibnizian monadology, the neo-vitalism of Hans Driesch, or, lastly, of the "phenomenology of organic life" in the 20th century, with authors such as Kurt Goldstein, Maurice Merleau-Ponty, and Georges Canguilhem. In this paper I try to reconstruct some of the main interpretive stages or layers of the concept of organism in order to evaluate it critically. How might organism be a useful concept if one rules out the excesses of organismic biology and metaphysics? Varieties of instrumentalism and what I call the projective concept of organism are appealing, but perhaps ultimately unsatisfying.

  13. Self-Assessment of Skills and Competencies among Residents Participating in a Pediatric Hospice and Palliative Medicine Elective Rotation. (United States)

    Rossfeld, Zachary M; Tumin, Dmitry; Humphrey, Lisa M


    To describe our institutional experience with a four-week pediatric HPM elective rotation and its impact on residents' self-rated competencies. In the spirit of bolstering primary hospice and palliative medicine (HPM) skills of all pediatricians, it is unclear how best to teach pediatric HPM. An elective rotation during residency may serve this need. An anonymous online survey was distributed to pediatric and internal medicine/pediatrics residents at a single, tertiary academic children's hospital. Respondents were asked to rate education, experience, and comfort with five aspects of communication with families of children with terminal illnesses and six domains of managing the symptoms of terminal illnesses. Self-ratings were recorded on a 1-5 scale: none, minimal, moderate, good, or excellent. Demographic data, including details of training and prior HPM training, were collected. Respondents completed a set of six questions gauging their attitude toward palliative care in general and at the study institution specifically. All respondents desire more HPM training. Those residents who self-selected to complete a pediatric HPM elective rotation had significantly higher self-ratings in 10 of 11 competency/skill domains. Free-text comments expressed concern about reliance on the specialty HPM team. A pediatric HPM elective can significantly increase residents' self-rated competency. Such rotations are an under-realized opportunity in developing the primary HPM skills of pediatricians, but wider adoption is restricted by the limited availability of pediatric HPM rotations and limited elective time during training.

  14. Mood dependence of perceived criticism: a significant null finding. (United States)

    Gerlsma, Coby; de Ruiter, Naomi M P; Kingma, Willem


    Five decades of research have shown that the quality of one׳s interactions with significant others, as captured in the expressed emotion (EE) concept, affects the course of various psychiatric and medical complaints. The key EE-component, interpersonal criticism, is increasingly assessed with the single-item Perceived Criticism Measure (PCM). The measure is highly practical and has shown good concurrent and predictive validity. Because the PCM relies on respondents׳ memories, ratings may be subject to mood bias. In this study we examined to what extent PCM-ratings are mood dependent. College students (N=150) provided data on mood and PCM before and after the induction of either a positive or negative mood. Although the mood induction was highly successful, PCM-ratings remained stable and appeared unaffected by changes in mood. This finding contradicts the robust mood-congruency-effect finding that the valence of one's mood enhances the recollection of similarly valenced memories. This apparent stability bolsters the PCM's construct validity and makes it less likely that high PCM-ratings simply reflect the negatively biased perceptions of distressed individuals. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  15. Social networks, mental health problems, and mental health service utilization in OEF/OIF National Guard veterans. (United States)

    Sripada, Rebecca K; Bohnert, Amy S B; Teo, Alan R; Levine, Debra S; Pfeiffer, Paul N; Bowersox, Nicholas W; Mizruchi, Mark S; Chermack, Stephen T; Ganoczy, Dara; Walters, Heather; Valenstein, Marcia


    Low social support and small social network size have been associated with a variety of negative mental health outcomes, while their impact on mental health services use is less clear. To date, few studies have examined these associations in National Guard service members, where frequency of mental health problems is high, social support may come from military as well as other sources, and services use may be suboptimal. Surveys were administered to 1448 recently returned National Guard members. Multivariable regression models assessed the associations between social support characteristics, probable mental health conditions, and service utilization. In bivariate analyses, large social network size, high social network diversity, high perceived social support, and high military unit support were each associated with lower likelihood of having a probable mental health condition (p social support (OR .90, CI .88-.92) and high unit support (OR .96, CI .94-.97) continued to be significantly associated with lower likelihood of mental health conditions. Two social support measures were associated with lower likelihood of receiving mental health services in bivariate analyses, but were not significant in adjusted models. General social support and military-specific support were robustly associated with reduced mental health symptoms in National Guard members. Policy makers, military leaders, and clinicians should attend to service members' level of support from both the community and their units and continue efforts to bolster these supports. Other strategies, such as focused outreach, may be needed to bring National Guard members with need into mental health care.

  16. The nursing profession in Sri Lanka: time for policy changes. (United States)

    Aluwihare-Samaranayake, D; Ogilvie, L; Cummings, G G; Gellatly, Ian R


    We address issues and challenges in nursing in Sri Lanka with the aim of identifying where and how policy changes need to be made. Increased global interconnectivity calls for professional leadership, research, education, and policy reform in nursing as these are identified as enhancing health workforce performance and professionalization, thereby improving health systems. We draw on first-hand knowledge of health care and nursing in Sri Lanka and a recent survey of nurses at a large urban government hospital in Sri Lanka, followed by discussion and proposed action on themes identified through analysis of published and unpublished literature about the nursing profession. Policy and action are needed to: (a) establish mandatory nurse licensure in the public and private healthcare sectors; (b) implement realistic policies to further develop nursing education; (c) develop a professionalization process to support nursing autonomy and voice; and (d) promote systematic processes for educational accreditation, curriculum revision, continuing professional development, evidence-based practice, research, leadership, and information systems. There is a policy vacuum that requires careful analysis and strategic planning by formal nurse leaders. Implementing change will require political and professional power and strategic, innovative, and evolutionary policy initiatives as well as organizational infrastructure modifications best achieved through committed multidisciplinary collaboration, augmented research capacity, bolstered nursing leadership, and promotion of partnerships with policy makers. © 2017 International Council of Nurses.

  17. The current status of local medicare payment policy: how specialty societies can influence local coverage determinations. (United States)

    Allen, Bibb; Pennington, Anita; Keysor, Kathryn J


    The Medicare Fee-for-Service Program is in the midst of numerous administrative and regulatory changes that may affect the way local Medicare payment policy is implemented. These changes involve redefining the contractors' jurisdictions, competitive bidding for the contractor selection process, combining the administration of Part A and Part B services, and error rate auditing. In addition, the roles of the Contractor Medical Directors and Contractor Advisory Committees are yet to be defined, and the future of the existing advisory process, while currently unchanged, remains uncertain. Most likely, the majority of coverage decisions will continue to be made at the local level; however, the Centers for Medicare & Medicaid Services (CMS) has begun to increase its use of Technology Assessments and National Coverage Determinations for new technology and has developed a new payment category for coverage of new technology: Coverage with Evidence Development. Specialty societies continue to have the ability to exert influence on the coverage process. The American College of Radiology (ACR) monitors the activity of the local contractors and assists local physicians through the ACR Carrier Advisory Committee Network. The ACR has used a combination of clinical and economic experts to develop model Local Coverage Determinations for use by the local contractors, and some of these model policies have been developed in conjunction with other specialty societies, which bolsters their effectiveness. The changing administrative environment presents challenges and opportunities for specialty societies to influence local CMS payment policy.

  18. Impact of a brief intervention on physical activity and social cognitive determinants among working mothers: a randomized trial. (United States)

    Mailey, Emily L; McAuley, Edward


    Working mothers exhibit high levels of inactivity, and theory-based interventions to bolster physical activity within this population are needed. This study examined the effectiveness of a brief social cognitive theory-based intervention designed to increase physical activity among working mothers. Participants (N = 141) were randomly assigned to an intervention only, intervention plus follow-up support, or waitlist control condition. The intervention consisted of two group-based workshop sessions designed to teach behavior modification strategies using social cognitive theory. Data were collected at baseline, immediately post-intervention, and 6-month follow-up. Results showed intervention participants exhibited short-term increases in physical activity, which were partially maintained 6 months later. Improvements in physical activity were mediated by increases in self-regulation and self-efficacy. This study provides some support for the effectiveness of a brief intervention to increase physical activity among working mothers. Future programs should explore alternative support mechanisms which may lead to more effective maintenance of initial behavior changes.

  19. Men as Allies Against Sexism

    Directory of Open Access Journals (Sweden)

    Sezgin Cihangir


    Full Text Available Sexism is often expressed in subtle and ambiguous ways, causing targets to doubt their own capabilities or to show stereotype-confirming behavior. This research examines whether the self-confidence and stereotype (dis-confirming behavior of targets of sexism can be bolstered when other male versus female sources suggest that sexism may have played a role. Both Study 1 (N = 78 and Study 2 (N = 90 show that a suggestion of sexism has more beneficial effects when it is made by male sources than when it is made by female sources. When males suggested that sexism had taken place, targets reported more self-confidence (less self-handicapping and higher personal performance state self-esteem and showed less stereotype confirmation (less self-stereotyping and better task performance than when sexism was suggested by a female source. Study 2 additionally revealed that targets are more likely to file a complaint when men suggest that sexism took place than when this same suggestion was made by women. These results indicate that men can constitute important allies against sexism if they speak out when sexist treatment takes place.

  20. Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

    International Nuclear Information System (INIS)

    Weir, Genevieve M.; Liwski, Robert S.; Mansour, Marc


    Chemotherapy has been a mainstay in cancer treatment for many years. Despite some success, the cure rate with chemotherapy remains unsatisfactory in some types of cancers, and severe side effects from these treatments are a concern. Recently, understanding of the dynamic interplay between the tumor and immune system has led to the development of novel immunotherapies, including cancer vaccines. Cancer vaccines have many advantageous features, but their use has been hampered by poor immunogenicity. Many developments have increased their potency in pre-clinical models, but cancer vaccines continue to have a poor clinical track record. In part, this could be due to an inability to effectively overcome tumor-induced immune suppression. It had been generally assumed that immune-stimulatory cancer vaccines could not be used in combination with immunosuppressive chemotherapies, but recent evidence has challenged this dogma. Chemotherapies could be used to condition the immune system and tumor to create an environment where cancer vaccines have a better chance of success. Other types of immunotherapies could also be used to modulate the immune system. This review will discuss how immune modulation by chemotherapy or immunotherapy could be used to bolster the effects of cancer vaccines and discuss the advantages and disadvantages of these treatments

  1. Hand-rearing, release and survival of African penguin chicks abandoned before independence by moulting parents. (United States)

    Sherley, Richard B; Waller, Lauren J; Strauss, Venessa; Geldenhuys, Deon; Underhill, Les G; Parsons, Nola J


    The African penguin Spheniscus demersus has an 'Endangered' conservation status and a decreasing population. Following abandonment, 841 African penguin chicks in 2006 and 481 in 2007 were admitted to SANCCOB (Southern African Foundation for the Conservation of Coastal Birds) for hand-rearing from colonies in the Western Cape, South Africa, after large numbers of breeding adults commenced moult with chicks still in the nest. Of those admitted, 91% and 73% respectively were released into the wild. There were veterinary concerns about avian malaria, airsacculitis and pneumonia, feather-loss and pododermatitis (bumblefoot). Post-release juvenile (0.32, s.e.  = 0.08) and adult (0.76, s.e.  = 0.10) survival rates were similar to African penguin chicks reared after oil spills and to recent survival rates recorded for naturally-reared birds. By December 2012, 12 birds had bred, six at their colony of origin, and the apparent recruitment rate was 0.11 (s.e.  = 0.03). Hand-rearing of abandoned penguin chicks is recommended as a conservation tool to limit mortality and to bolster the population at specific colonies. The feasibility of conservation translocations for the creation of new colonies for this species using hand-reared chicks warrants investigation. Any such programme would be predicated on adequate disease surveillance programmes established to minimise the risk of disease introduction to wild birds.

  2. Making the innovation case in Open Access scholary communication

    CERN Multimedia

    CERN. Geneva


    It seems almost unnecessary to have to elaborate additional reasons for the adoption of Open Access scholarly communication (OA sc) as manifested through Open Access journals and self-archiving practices. To those active within the OA arena, the case has been convincingly made, and current arguments merely need to be disseminated beyond the Library and Information Science (LIS) sphere. However, it is my contention that a convincing argument for OA sc needs to be launched from the Science Policy perspective if any government mandated pro-OA policy changes are to be effected. This paper, then, is an attempt at taking the OA discussion beyond the LIS arena and into the realm of Science and Innovation Policy. Using Innovation Theory as its theoretical framework, it is argued that Open Access scholarly communication can only serve to bolster Innovation Systems, be they national, regional, or sectoral. The case of South Africa is taken as an illustrative example, though the case can and will be generalised to beyon...

  3. Educating the Psychology Workforce in the Age of the Affordable Care Act: A Graduate Course Modeled after the Priorities of the Patient-Centered Outcomes Research Institute (PCORI) (United States)

    Hoerger, Michael


    The Affordable Care Act (ACA) represents a paradigm shift in the U.S. healthcare system, which has implications for psychology programs producing the next generation of trainees. In particular, the ACA has established the Patient-Centered Outcomes Research Institute (PCORI), which has been tasked with developing national priorities and funding research aimed at improving healthcare quality by helping patients and providers to make informed healthcare decisions. PCORI's national priorities span five broad domains: person-centered outcomes research, health disparities research, healthcare systems research, communication and dissemination research, and methodologic research. As these national priorities overlap with the knowledge and skills often emphasized in psychology training programs, initiatives by training programs to bolster strengths in these domains could place trainees at the forefront of this emerging research paradigm. As a part of a new Masters program in behavioral health, our program developed a health psychology course modeled around PCORI's five national priorities, and an initial evaluation in a small sample supported student learning in the five PCORI domains. In summary, the current report has implications for familiarizing readers with PCORI's national priorities for U.S. healthcare, stimulating debate surrounding psychology's response to the largest healthcare paradigm shift in recent U.S. history, and providing a working model for programs seeking to implement PCORI-related changes to their curricula. PMID:26843899

  4. Low level light in combination with metabolic modulators for effective therapy (United States)

    Dong, Tingting; Zhang, Qi; Hamblin, Michael R.; Wu, Mei X.


    Vascular damage occurs frequently at the injured brain causing hypoxia and is associated with poor outcomes in the clinics. We found high levels of glycolysis, reduced ATP generation, and increased formation of reactive oxygen species (ROS) and apoptosis in neurons under hypoxia. Strikingly, these adverse events were reversed significantly by noninvasive exposure of injured brain to low-level light (LLL). LLL illumination sustained the mitochondrial membrane potential, constrained cytochrome C leakage in hypoxic cells, and protected them from apoptosis, underscoring a unique property of LLL. The effect of LLL was further bolstered by combination with metabolic substrates such as pyruvate or lactate both in vivo and in vitro. The combinational treatment retained memory and learning activities of injured mice to a normal level, whereas those treated with LLL or pyruvate alone, or sham light displayed partial or severe deficiency in these cognitive functions. In accordance with well-protected learning and memory function, the hippocampal region primarily responsible for learning and memory was completely protected by a combination of LLL and pyruvate, in marked contrast to the severe loss of hippocampal tissue due to secondary damage in control mice. These data clearly suggest that energy metabolic modulators can additively or synergistically enhance the therapeutic effect of LLL in energy-producing insufficient tissues like injured brain. Keywords:

  5. Encuentro: Feasibility, Acceptability, and Outcomes of a Culturally Tailored Teen-Parent Health Promotion Program. (United States)

    Sieving, Renee E; Allen, Michele L; Galvan, Adriana; Rodriguez-Hager, Rosemarie; Beckman, Kara; Castillo, Marina; Gadea, Abigail; Jimbo-Llapa, Fanny; Porta, Carolyn; Svetaz, Maria Veronica


    The growth of the Latino youth population, combined with the reality that many Latino adolescents live in environments characterized by social disparities, reveals a compelling need to address health inequalities affecting Latinos through effective health promotion programs designed by and for this population. This article presents findings from a pilot study of Encuentro, a health promotion program for young Latino teens and their parents. Developed by a community-university partnership, Encuentro aims to bolster internal assets, familial and cultural supports for young teens' positive development, and healthy sexual decision making and behaviors. Encuentro was pilot tested with 49 Latino families at 3 community sites in Minneapolis/St. Paul. Families were assigned to a program group or a control group. Pilot study findings confirm program feasibility and acceptability. Compared to the control group, program group youth reported substantially more involvement in activities celebrating Latino culture, and greater communication with their parents about sexual health topics. Parents in the program group reported greater ethnic pride, engaging in more activities to share Latino values and traditions with their teens, greater communication with their teens about sexual health topics, and increased parental monitoring than did parents in the control group. Findings demonstrate the potential of the Encuentro program.

  6. From Lydia Pinkham to Bob Dole: what the changing face of direct-to-consumer drug advertising reveals about the professionalism of medicine. (United States)

    Pinkus, Rosa Lynn


    From its founding in 1847, the AMA divided drugs into "ethical" and "unethical" preparations. Those that were ethical had a known composition and were advertised only to the profession. Other, patent medicines (technically proprietary drugs, whose trademarks were protected by copyright), were sold directly to the public. In spite of the AMA's efforts to ban the advertising and sale of those nostrums, proprietary drugs flourished during the nineteenth century. Starting in 1900, however, three major societal trends combined to bolster the AMA's campaign, and by 1920 almost all advertising was directed to physicians, who would then prescribe medications to their patients. This ban on advertising pharmaceuticals directly to the public remained virtually unchanged until approximately 1980. Since then, it has slowly eroded and, as recently as 1997, the FDA created guidelines for pharmaceutical companies to advertise on television. What does this change say about the profession of medicine, the role of the physician in society, and the doctor-patient relationship? Using a comparative historical approach, this paper examines these issues.

  7. A social media program to increase adolescent seat belt use. (United States)

    Drake, Stacy A; Zhang, Ni; Applewhite, Courtney; Fowler, Katherine; Holcomb, John B


    In response to motor vehicle crashes remaining the leading cause of death for teenagers in the United States, a nursing clinical group (n = 10) in conjunction with a local hospital injury prevention program created an educational campaign to bolster seat belt use. The nursing students created an Instagram account to serve as an educational tool to promote seat belt use among teenagers aged 14-19, and the program was presented at three high school health fairs. In all, 135 postings were made to the account over a 3-month period. The number of likes posted by high school students was the unit of analysis. The most significant result (p = .01) was the difference between postings most liked (celebrities wearing seat belts) and least liked (postings made at the high school health fair), otherwise, differences among postings liked (humor postings, response requests, pictures of celebrities, factual data) were not significant. Instagram user engagement, measured in number of likes, is indicative that social media provides platforms to promote injury prevention efforts. Further research is needed to identify measurable elements of social media and to follow-up on behavioral changes following participation. © 2017 Wiley Periodicals, Inc.

  8. Canadian oilsands, heavy oil poised for surge in development

    International Nuclear Information System (INIS)



    Operators in Canada's oilsands and heavy oil regions are on the brink of a period of growth that could last well into the next century. Several factors are combining in a scenario a National Task Force report on oilsands says could dramatically increase investment and production in the next 25 years. By then, massive oilsands and heavy oil reserves in northern Alberta could account for as much as 50%--perhaps more--of Canada's oil production. Technological improvements in recovery and processing have slashed production costs and put nonconventional oil on a more competitive footing with declining reserves of conventional crude in western Canada. At the same time, persistent lobbying by industry and a well researched national study have persuaded federal and provincial governments to introduce a new royalty and fiscal regime designed to bolster oilsands investment. New policies give clear incentives to investors to put money into oilsands and heavy oil projects. Policies also will provide a generic tax treatment for all new projects, long a major objective of oilsands promoters. Previously, royalty and tax agreements were negotiated for project case by case. This paper reviews the resource base and the new operational developments resulting from these policies

  9. A Novel Dual–Parallelogram Passive Rocking Vibration Isolator: A Theoretical Investigation and Experiment

    Directory of Open Access Journals (Sweden)

    Shuai Wang


    Full Text Available Vibration isolators with quasi-zero stiffness (QZS perform well for low- or ultra-low-frequency vibration isolation. This paper proposes a novel dual-parallelogram passive rocking vibration isolator with QZS that could effectively attenuate in-plane disturbances with low-frequency vibration. First, a kinematic model of the proposed vibration isolator was established and four linear spring configuration schemes were developed to implement the QZS. Next, an optimal scheme with good high-static-low-dynamic stiffness (HSLDS performance was obtained through comparison and analysis, and used as a focus for the QZS model. Subsequently, a dynamic model-based Lagrangian equation that considered the spring stiffness and damping and the influence of the payload gravity center on the vibration isolation system was developed, and an average approach was used to analyze the vibration transmissibility. Finally, the prototype and test system were constructed. A comparison of the simulation and experimental results showed that this novel passive rocking vibration isolator could bolster a heavy payload. Experimentally, the vibration amplitude decreased by 53% and 86% under harmonic disturbances of 0.08 Hz and 0.35 Hz, respectively, suggesting the great practical applicability of this presented vibration isolator.

  10. Financial Performance of Socially Responsible Firms: The Short- and Long-Term Impact

    Directory of Open Access Journals (Sweden)

    Maria J. Charlo


    Full Text Available The pressure of society for firms to adopt socially responsible behavior is evident. Yet, Corporate Social Responsibility (CSR needs an economic justification. In response to this, there exists a comprehensive literature that analyzes the possible relation between social and business financial performance. During the last decade, the literature has been heading toward the carrying out of dynamic studies as researches find that the relationship between social and financial performance is not static. The purpose of this work is to analyze the relevance for the financial performance of Spanish listed firms of maintaining their responsible behavior. To do so, we carry out a comparison between two analyses—one cross-sectional, and the other longitudinal—to be able to conclude whether or not adopting responsible criteria makes a difference in business financial performance in the short and long-term. Some of the results obtained in the cross-sectional study are consolidated in the long-term study. In this sense, responsible firms exhibit a higher systematic risk and have greater size. As a conclusion, be responsible does not mean less stock profitability or a lower business result. It certainly contributes to firms continuing to voluntarily incorporate good corporate social responsibility practices into their business models. What is more, these results support the governmental policies and initiatives that bolster corporate social responsibility.

  11. Ensuring Resilience of Natural Resources under Exposure to Extreme Climate Events

    Directory of Open Access Journals (Sweden)

    Brent Jacobs


    Full Text Available Natural resources directly support rural livelihoods and underpin much of the wealth of rural and regional Australia. Climate change manifesting as increasing frequency and or severity of extreme weather events poses a threat to sustainable management of natural resources because the recurrence of events may exceed the resilience of natural systems or the coping capacity of social systems. We report the findings of a series of participatory workshops with communities in eight discrete landscapes in South East New South Wales, Australia. The workshops focused on how natural resource management (NRM is considered in the Prevent-Prepare-Respond-Recover emergency management cycle. We found that NRM is generally considered only in relation to the protection of life and property and not for the intrinsic value of ecosystem services that support communities. We make three recommendations to improve NRM under extreme climate events. Firstly, the support to communities offered by emergency management agencies could be bolstered by guidance material co-produced with government NR agencies. Secondly, financial assistance from government should specifically target the restoration and maintenance of green infrastructure to avoid loss of social-ecological resilience. Thirdly, action by natural resource dependent communities should be encouraged and supported to better protect ecosystem services in preparation for future extreme events.

  12. The role of the neuro-astro-vascular unit in the etiology of Ataxia Telangiectasia

    Directory of Open Access Journals (Sweden)

    Leenoy eMeshulam


    Full Text Available The growing recognition that brain pathologies do not affect neurons only but rather are, to a large extent, pathologies of glial cells as well as of the vasculature opens to new perspectives in our understanding of genetic disorders of the CNS. To validate the role of the neuron-glial-vascular unit in the etiology of genome instability disorders, we report about cell death and morphological aspects of neuro-glia networks and the associated vasculature in a mouse model of Ataxia Telangiectasia (A-T, a human genetic disorder that induces severe motor impairment. We found that AT-mutated protein deficiency was consistent with aberrant astrocytic morphology and alterations of the vasculature, often accompanied by reactive gliosis. Interestingly similar findings could also be reported in the case of other genetic disorders. These observations bolster the notion that astrocyte-specific pathologies, hampered vascularization and astrocyte-endothelium interactions in the CNS could play a crucial role in the etiology of genome instability brain disorders and could underlie neurodegeneration.

  13. Childhood Maltreatment, Self-Esteem, and Suicidal Ideation in a Low-Ses Emerging Adult Sample: The Moderating Role of Heart Rate Variability. (United States)

    Duprey, Erinn Bernstein; Oshri, Assaf; Liu, Sihong


    Objectives Childhood maltreatment is associated with risk for suicidal ideation later in life, yet more research is needed on the indirect effects and bioregulatory protective factors in this association. The present study aimed to investigate the indirect influence of childhood maltreatment on suicidal ideation in emerging adulthood via level of self-esteem, and examine the moderating role of heart rate variability (HRV; a proxy for emotion regulation) in this indirect association. Methods The study included a sample of 167 non-metropolitan emerging adults (M age  = 21.17, 55.8% female) of low-socioeconomic status (low-SES). HRV data was obained using an electrocardigram, whereas childhood maltreatment, suicidal ideation, and self-esteem data were obtained via self-report. Results Childhood maltreatment was indirectly associated with suicidal ideation via reduced self-esteem. HRV buffered this indirect association. Conclusions Childhood maltreatment poses a risk for the development of suicidal ideation. Interventions that bolster self-esteem and emotion regulation may reduce suicide risk for emerging adults with a history of childhood maltreatment.

  14. Design and methods for a randomized clinical trial treating comorbid obesity and major depressive disorder. (United States)

    Schneider, Kristin L; Bodenlos, Jamie S; Ma, Yunsheng; Olendzki, Barbara; Oleski, Jessica; Merriam, Philip; Crawford, Sybil; Ockene, Ira S; Pagoto, Sherry L


    Obesity is often comorbid with depression and individuals with this comorbidity fare worse in behavioral weight loss treatment. Treating depression directly prior to behavioral weight loss treatment might bolster weight loss outcomes in this population, but this has not yet been tested in a randomized clinical trial. This randomized clinical trial will examine whether behavior therapy for depression administered prior to standard weight loss treatment produces greater weight loss than standard weight loss treatment alone. Obese women with major depressive disorder (N = 174) will be recruited from primary care clinics and the community and randomly assigned to one of the two treatment conditions. Treatment will last 2 years, and will include a 6-month intensive treatment phase followed by an 18-month maintenance phase. Follow-up assessment will occur at 6-months and 1- and 2 years following randomization. The primary outcome is weight loss. The study was designed to provide 90% power for detecting a weight change difference between conditions of 3.1 kg (standard deviation of 5.5 kg) at 1-year assuming a 25% rate of loss to follow-up. Secondary outcomes include depression, physical activity, dietary intake, psychosocial variables and cardiovascular risk factors. Potential mediators (e.g., adherence, depression, physical activity and caloric intake) of the intervention effect on weight change will also be examined. Treating depression before administering intensive health behavior interventions could potentially boost the impact on both mental and physical health outcomes. NCT00572520.

  15. Promoting homework adherence in cognitive-behavioral therapy for adolescent depression. (United States)

    Jungbluth, Nathaniel J; Shirk, Stephen R


    This study used prospective, observational methods to evaluate six features of therapist behavior as predictors of homework adherence in cognitive-behavioral therapy for adolescent depression, with the goal of identifying therapist strategies with the potential to improve adolescent adherence. Therapist behaviors were expected to interact with initial levels of client resistance or adherence to predict subsequent homework completion. Participants were 50 referred adolescents (33 female, 54% ethnic minority) ages 14 to 18 (M = 15.9) meeting diagnostic criteria for a depressive disorder, and without comorbid psychotic disorder, bipolar disorder, autism spectrum disorder, intellectual disability, or concurrent treatments. Therapist homework-related behaviors were coded from audiotapes of Sessions 1 and 2 and used to predict adolescents' homework adherence, coded from audiotapes of Sessions 2 and 3. Several therapist behaviors were predictive of subsequent homework adherence, particularly for initially resistant or nonadherent adolescents. Stronger homework rationale and greater time allocated to explaining homework in Session 1 predicted greater adherence at Session 2, particularly for initially resistant adolescents. Stronger rationale and eliciting reactions/troubleshooting obstacles in Session 2 predicted greater adherence at Session 3, particularly for adolescents who were less adherent to prior homework. Strategies such as providing a strong rationale, allocating more time to assigning homework, and eliciting reactions/troubleshooting obstacles may be effective ways to bolster homework adherence among initially less engaged, depressed teens.

  16. Advocacy Coalition for Safer Sex in the Adult Film Industry: The Case of Los Angeles County's Measure B. (United States)

    Cohen, Adam Carl; Tavrow, Paula; McGrath, Mark Roy


    Performers in the adult film industry are routinely exposed to bloodborne pathogens. In 2012, public health advocates in Los Angeles County convinced voters to pass a ballot initiative-Measure B-to mandate condom use on adult film sets. This article presents a case study of the advocacy coalition's strategies used to achieve greater workplace safety using the advocacy coalition framework. The authors were given access to all memoranda, market research, and campaign tools used to promote Measure B. To reconstruct adult film industry counterefforts, the authors reviewed trade publications, social media, and blog posts. When legislative efforts failed, advocates engaged in a step-by-step strategy built around voters to achieve passage of a ballot initiative mandating condom use for all adult films produced in Los Angeles County. Although the industry immediately filed a lawsuit after passage of Measure B, its constitutionality has been upheld. Measure B passed because public health advocates were able to assemble scientific evidence, build public support, counter false claims, and maintain consistent messages throughout the campaign. The adult film industry lacked social capital, cohesion, and nimbleness. To bolster regulatory efforts, appealing to voters to favor safe workplaces may be an effective advocacy strategy for other industries.

  17. Livestock policy and trade issues in SADC. (United States)

    Hulman, B


    As from 2001, the Southern African Development Community (SADC) has embarked on a course to deepen regional integration through restructuring. Under the new structure SADC has centralised the coordination of its activities to the Secretariat in Gaborone. The former Sector Coordinating Units have been merged into four directorates, one of which is the Food, Agriculture and Natural Resources (FANR) Directorate, which comprises, amongst others, the Livestock Development Unit (LDU). The LDU, under the aegis of the FANR, formulates policies for regional livestock development in order to respond to the objectives of the Regional Indicative Strategic Development Plan (RISDP), and which are mainly to: Contribute to improved food security, Promote wealth creation, Enhance rural livelihood, Enhance livestock as a tradable and consumable commodity. Following the launch of the SADC Economic Partnership Agreement (EPA) negotiations, the eight SADC EPA member states identified sanitary and phytosanitary and technical barriers to trade to be major trade barriers for access to international markets, especially the EU market where standards are normally set beyond international standards. SADC has already brought some of the issues related to beef exports to the OIE Regional Commission for Africa as SADC member states feel that a few of the present requirements do not have a scientific basis. The paper discusses the process that the LDU follows in the formulation of policies and strategies in regional livestock development with the objective of bolstering intra and extra regional trade in livestock and livestock products.

  18. Racial science, geopolitics, and empires: paradoxes of power. (United States)

    Tilley, Helen


    Scholars interested in the history of racial science continue to puzzle over the ways in which such ideas endure. This essay takes up a variant on this theme by considering how critiques of ideas about racial purity and hierarchies, expressed at the Universal Races Congress of 1911, were part of a larger intellectual project that simultaneously under- mined ideas of fixed racial types and bolstered identity categories defined in racial terms. Efforts to destabilize racial science in the early decades of the twentieth century often went hand in glove with burgeoning critiques of "white" and European domination in different parts of the world. This essay shines the spotlight on the paradoxical nature of these processes. While anthropologists helped to spearhead attempts to deconstruct mainstream pillars of racial science, they also left the door open for its reconstitution by refusing to reject classificatory schemes by group. And though global conversations about race and science tended to generate more cosmopolitan and egalitarian views, the very act of bringing together people from different places had the unintended effect of reinforcing racial identities and idioms, especially in the context of challenges to colonial rule. Finally, even as state building within empires ensured that racial taxonomies proliferated on the ground, imperial bureaucrats often avoided promoting racial science and research because such endeavors were a divisive force in transnational management.

  19. The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor

    Directory of Open Access Journals (Sweden)

    Joseph Franz


    Full Text Available Interleukin- (IL- 22 signaling is protective in animal models of pneumonia and bacteremia by Klebsiella pneumoniae and mediates tissue recovery from influenza and Staph aureus infection. We recently described processing of mouse lung epithelial IL-22 receptor (IL-22R by ubiquitination on the intracellular C-terminal. To identify cellular factors that regulate human IL-22R, we screened receptor abundance while overexpressing constituents of the ubiquitin system and identify that IL-22R can be shuttled for degradation by multiple previously uncharacterized F-box protein E3 ligase subunits. We observe that in human cells IL-22R is destabilized by FBXW12. FBXW12 causes depletion of endogenous and plasmid-derived IL-22R in lung epithelia, binds the E3 ligase constituent Skp-1, and facilitates ubiquitination of IL-22R in vitro. FBXW12 knockdown with shRNA increases IL-22R abundance and STAT3 phosphorylation in response to IL-22 cytokine treatment. FBXW12 shRNA increases human epithelial cell growth and cell cycle progression with enhanced constitutive activity of map kinases JNK and ERK. These findings indicate that the heretofore-undescribed protein FBXW12 functions as an E3 ligase constituent to ubiquitinate and degrade IL-22R and that therapeutic FBXW12 inhibition may enhance IL-22 signaling and bolster mucosal host defense and infection containment.

  20. Central venous catheters for chronic hemodialysis: Is "last choice" never the "right choice"? (United States)

    Dumaine, Chance S; Brown, Robert S; MacRae, Jennifer M; Oliver, Matthew J; Ravani, Pietro; Quinn, Robert R


    Since the publication of the first vascular access clinical practice guidelines in 1997, the global nephrology community has dedicated significant time and resources toward increasing the prevalence of arteriovenous fistulas and decreasing the prevalence of central venous catheters for hemodialysis. These efforts have been bolstered by observational studies showing an association between catheter use and increased patient morbidity and mortality. To date, however, no randomized comparisons of the outcomes of different forms of vascular access have been conducted. There is mounting evidence that much of the difference in patient outcomes may be explained by patient factors, rather than choice of vascular access. Some have called into question the appropriateness of fistula creation for certain patient populations, such as those with limited life expectancy and those at high risk of fistula-related complications. In this review, we explore the extent to which catheters and fistulas exhibit the characteristics of the "ideal" vascular access and highlight the significant knowledge gaps that exist in the current literature. Further studies, ideally randomized comparisons of different forms of vascular access, are required to better inform shared decision making. © 2017 Wiley Periodicals, Inc.

  1. Precipitation Insights From Vertically Pointing Radar, Surveillance Radar and Disdrometers During the Two-Year GoAmazon2014/5 (United States)

    WANG, D.; Giangrande, S. E.; Hardin, J. C.; Feng, Z.; Bartholomew, M. J.; Toto, T.


    The Green Ocean Amazon (GoAmazon2014/5) field campaign recently concluded a remote two-year deployment in the central Amazon Basin to study cloud-aerosol-precipitation interactions. As part of GoAmazon2014/5, the Atmospheric Radiation Measurement (ARM) Mobile Facility (AMF) collected a unique set of observations in a region of strong climatic significance near Manacapuru, Brazil, a site known to experience both the pristine condition of its locale, as well as the effects of the Manaus, Brazil, mega city pollution plume. In addition to standard ARM cloud radar observations, this AMF deployment was equipped to capture a complete, continuous record of cloud and precipitation profiling and spatial properties, capitalizing on a reconfigured UHF (915 MHz) radar wind profiler (RWP) and collocated surface disdrometer measurements under the umbrella of the System for the Protection of Amazonia (SIPAM) S-band surveillance radar. Together, these sensors bolster multiple methods to understand detail precipitation processes, including explorations into the controls of large-scale synoptic, precipitation regimes (wet/dry seasons), diurnal cycle, and possible aerosol contributions. Of interest to climate model validation and convective parameterization improvement are new Amazon insights into rainfall characteristics, drop size distribution evolution, and relationships between storm storm dynamical/thermodynamical properties.

  2. Self-directed learning modules of CT scan images to improve students' perception of gross anatomy. (United States)

    Kumar, Pananghat Achutha; Jothi, Ramakrishnan; Mathivanan, Dharmalingam


    A contemporary anatomy curriculum that aims to be clinically relevant requires medical students to be introduced to radiological anatomy in the preclinical years. Ideally, the curriculum should also support self-directed learning, a habit best instilled early. Based on these educational requirements, we designed an interesting and clinically-meaningful program of self-learning modules in radiological anatomy to augment students' learning of gross anatomy. The program is guided by current theories of learning, which emphasize an individualized learning pace for students. This program uses enlarged computerized tomography (CT) scan images and associated resource materials. Scans are posted on the first day of the week in a public area for students to review on their own time. On the second day penciled outlines of important structures are provided to help students identify structures, and students are encouraged to discuss the images with faculty. On the last day of the week the identity of the structures are revealed to students. An open-ended questionnaire used to evaluate the program revealed that 95.5% of students used the program and a great majority recommended the program should be continued for future students. The present program enhances learning of gross anatomical relations through having students use visual clues in logically interpreting unlabeled CT scans in an organized and sequential way. The program promotes self-directed learning. In addition to its use with preclinical students, the modules might also help students in the clinical phase of the curriculum bolster their knowledge of spatial anatomy.

  3. Comparison between a 13-session and one-time program on Korea elementary, middle and high school students' understanding of nuclear power

    Energy Technology Data Exchange (ETDEWEB)

    Han, Eun Ok; Choi, Yoon Seok [Dept. of Education and Research, Korea Academy of Nuclear Safety, Seoul (Korea, Republic of); Lim, Young Khi [Dept. of Radiological Science, Gachon University, Incheon (Korea, Republic of)


    To help future generations make accurate value judgments about nuclear power generation and radiation, this study will provide an effective education plan suitable for South Korea by applying and analyzing programs for the understanding of nuclear power within the diversely operated programs in the current Korean education system. This study analyzed the difference in educational effects by operating a 13-session regular curriculum for one semester and a one-session short-term curriculum from March to July 2016. As a result of operating a 13-session model school and a one-time educational program to analyze behavior changes against the traditional learning model, it was found that all elementary, middle and high school students showed higher acceptability of nuclear power in South Korea. The variation was greater for the model school than the short-term program. To prevent future generations from making biased policy decisions stemming from fear regarding nuclear power, it is necessary to bolster their value judgments in policy decisions by acquiring sufficient information about nuclear power generation and radiation through educational programs.

  4. Older people living alone at home with terminal cancer. (United States)

    Aoun, S; Deas, K; Skett, K


    This study describes the lived experiences of older people coping with terminal cancer and living alone, focusing on how they face challenges of the biographical life changes from their disease progression. Face-to-face semi-structured interviews were conducted in two phases with palliative care clients of a community-based service in Western Australia (2009-2011): Brief interviews with 43 cancer patients who live alone and then in-depth interviews with 8 of them. Using biographical disruption as the analytical framework for interpreting the qualitative data, four main themes emerged: Biographical disruption: adjusting to change; Biographical continuity: preserving normality; Biographical reconstruction: redefining normality; and Biographical closure: facing the end. Biographical disruption was a suitable framework for analysis, permitting identification of the biographical disruptions of the individual's world and the reframing that is undertaken by the individual to maintain autonomy and independence while acknowledging and accepting their closeness to death. Understanding the factors associated with the individual's need to maintain their own identity will enable nurses working with this population to tailor support plans that meet the individuals' needs while maintaining or restoring the person's sense of self. Interventions that directly address end-of-life suffering and bolster sense of dignity and personhood need to be considered. © 2015 John Wiley & Sons Ltd.

  5. CBirTox is a selective antigen-specific agonist of the Treg-IgA-microbiota homeostatic pathway.

    Directory of Open Access Journals (Sweden)

    Katie L Alexander

    Full Text Available Cultivating an environment of mutualism between host cells and the microbiota is vital, and dysregulation of this relationship is associated with multiple immune disorders including metabolic and skin diseases, asthma, allergy, and Inflammatory Bowel Disease (IBD. One prominent mechanism for maintaining homeostasis is the protective regulatory T cell (Treg- Immunoglobulin A (IgA pathway toward microbiota antigens, in which Tregs maintain homeostasis and provide critical survival factors to IgA+ B cells. In order to amplify the Treg-IgA pathway, we have generated a fusion protein, CBirTox, comprised of a portion of the carboxy terminus of CBir1, a microbiota flagellin, genetically coupled to Cholera Toxin B subunit (CTB via the A2 linker of CT. Both dendritic cells (DCs and B cells pulsed with CBirTox selectively induced functional CD4+Foxp3+ Tregs in vitro, and CBirTox augmented CD4+Foxp3+ cell numbers in vivo. The induced Foxp3 expression was independent of retinoic acid (RA signaling but was inhibited by neutralization of TGF-β. CBirTox treatment of B cells downregulated mammalian target of rapamycin (mTOR signaling. Furthermore, CBirTox-pulsed DCs induced substantial production of IgA from naïve B cells. Collectively these data demonstrate that CBirTox represents a novel approach to bolstering the Treg-IgA pathway at the host-microbiota interface.

  6. Characterizing Normal Bowel Frequency and Consistency in a Representative Sample of Adults in the United States (NHANES). (United States)

    Mitsuhashi, Shuji; Ballou, Sarah; Jiang, Zhenghui G; Hirsch, William; Nee, Judy; Iturrino, Johanna; Cheng, Vivian; Lembo, Anthony


    Our current understanding of normal bowel patterns in the United States (US) is limited. Available studies have included individuals with both normal and abnormal bowel patterns, making it difficult to characterize normal bowel patterns in the US. The current study aims to (1) examine frequency and consistency in individuals with self-reported normal bowel habits and (2) determine demographic factors associated with self-reported normalcy. This study used data from adult participants who completed bowel health questions as part of the National Health and Nutrition Examination Survey (NHANES) in 2009-2010 and who reported normal bowel patterns (N=4,775). Data regarding self-perceived bowel health; stool frequency; stool consistency (using the Bristol Stool Form Scale (BSFS)); and demographic factors were analyzed. 95.9% of the sample reported between 3 and 21 BMs per week. Among men, 90% reported a BSFS between 3 and 5, while for women it was 2-6. After controlling for age, the following demographic variables were associated with normalcy: male sex, higher education, higher income, normal bowel frequency and consistency in a representative sample of adults in the US. The current findings bolster the common "3 and 3" metric of normal frequency (3 BMs/day to 3 BMs/week) while also suggesting different criteria for normal consistency for men and women. Finally, this study provides novel information about demographic factors associated with normal frequency and consistency.

  7. Interim report on nodel evaluation methodology and the evaluation of LEAP

    Energy Technology Data Exchange (ETDEWEB)

    Alsmiller, R.G. Jr.; Barish, J.; Bjornstad, D.


    This report describes progress made at ORNL toward development and demonstration of a methodology for evaluating energy-economic modeling codes and important results derived from these codes. To bolster traditional evaluation methods with more-quantitative procedures of interest to the Energy Information Administration, ORNL is applying sensitivity theory as part of a comprehensive effort to quantify the importance of various data and model parameters to the key results that are of interest. The Long-Term Energy Analysis Program (LEAP) was chosen as the initial focus for the research. LEAP is an energy-economy model which resides in the Long-Term Energy Analysis Division (LTEAD) of the Integrative Analysis Group in the Office of Applied Analysis, EIA. LTEAD developed Model 22C of LEAP for two reasons: (1) to prepare projections through the year 2020, which were needed for the 1978 EIA Annual Report to Congress and (2) to develop a base for analyses of specific options for Federal action. LEAP Model 22C and its uses are described to provide the background for this interim description of the model evaluation effort at ORNL. 19 figures, 10 tables.

  8. Effect of an antismoking advertisement on cinema patrons' perception of smoking and intention to smoke: a quasi-experimental study. (United States)

    Hanewinkel, Reiner; Isensee, Barbara; Sargent, James D; Morgenstern, Matthis


    To assess the effect of an antismoking advertisement under real-world conditions. Design Quasi-experimental study. Multiplex cinema in Kiel, Germany; 4073 patrons were surveyed after having viewed a movie. Some 4005 patrons were > or = 10 years old (28.7% between 10 and 17 years). A total of 654 subjects (16.3%) were smokers. In the intervention condition (weeks 1 and 3), a 30-second antismoking advertisement-accentuating long-term health consequences of smoking and promoting cessation-was shown prior to all movies; in the control condition (weeks 2 and 4) no such spot was shown. (i) Awareness of smoking in the movie, (ii) approval of smoking in the movie, (iii) attitude towards smoking, (iv) intention to smoke in the future and (v) desire to smoke among smokers. Findings Patrons who were exposed to the antismoking advertisement were more likely to be female, but did not differ with respect to smoking status. After controlling for gender differences, patrons exposed to the antismoking advertisement had (i) higher awareness of smoking in the movies, (ii) lower levels of approval of smoking in the movies, and (iii) a more negative attitude towards smoking in general compared with those not exposed. Among smokers, smoking in the movies increased urge to smoke, but there was no interaction between smoking in the movies and experimental condition. Study results suggest that placing an antismoking advertisement before movies can affect attitudes towards smoking, bolstering evidence in support of such policies.

  9. Beyond traditional scientific training: The importance of community and empowerment for women in ecology and evolutionary biology

    Directory of Open Access Journals (Sweden)

    M. Claire Horner-Devine


    Full Text Available While the biological sciences have achieved gender parity in the undergraduate and graduate career stages, this is not the case at the faculty level. The WEBS (Women Evolving the Biological Sciences symposia go beyond traditional scientific training and professional development to address factors critical to women’s persistence in faculty careers: community and empowerment. Through a series of panel discussions, personal reflections and skills workshops, WEBS creates a community-based professional development experience and a space for participants to grapple with central issues affecting their scientific careers. Longitudinal qualitative survey data suggest that WEBS bolsters the participants’ confidence and empowerment, in addition to providing concrete skills for addressing a range of issues necessary to navigating scientific careers, leading to increased career satisfaction and career self-efficacy (i.e., the belief in one’s capacity to pursue their chosen career. These results highlight the importance and need for programs and opportunities for women in STEM that go beyond training in scientific skills and traditional professional development to include those that create a sense of community and empowerment.


    Directory of Open Access Journals (Sweden)

    Riski Amanuloh


    Full Text Available The purpose of this research is to improve student learning outcomes through audio-visual media in teaching gymnastics at the front of the class bolsters SMP Negeri 5 Semarang. This study used a descriptive quantitative research methods and types of research is a class action consisting of four stages : planning , action , observation , and reflection. Data collection techniques used were tests , observation sheets and questionnaires. In the first cycle of learning outcomes obtained a mean score of 70.2 category ( good taken from three aspects, namely psychomotor assessment criteria a mean value ( 71.8 , affective a mean value ( 68.5 and cognitive the mean value ( 70.4 , the results it can be concluded that student learning outcomes are good enough but needs to be improved. While in Cycle II study results obtained mean score of 85.8 category ( good taken from three aspects , namely psychomotor assessment criteria with a mean value ( 88.3 , affective with a mean value ( 85.0 and cognitive with the mean value ( 84.2 , of the results can be concluded that student learning outcomes have been good ( Completed All in keeping with KKM in the set , namely ( 80.00 . Can be summed scores increased student learning outcomes . Thus the use of audio-visual media in teaching learning gymnastics forward roll can increase motivation , comprehension and learning outcomes eighth grade students of SMP Negeri 5 Semarang .

  11. Longitudinal analysis of minority women’s perceptions of cohesion: the role of cooperation, communication, and competition (United States)


    Background Interaction in the form of cooperation, communication, and friendly competition theoretically precede the development of group cohesion, which often precedes adherence to health promotion programs. The purpose of this manuscript was to explore longitudinal relationships among dimensions of group cohesion and group-interaction variables to inform and improve group-based strategies within programs aimed at promoting physical activity. Methods Ethnic minority women completed a group dynamics-based physical activity promotion intervention (N = 103; 73% African American; 27% Hispanic/Latina; mage = 47.89 + 8.17 years; mBMI = 34.43+ 8.07 kg/m2) and assessments of group cohesion and group-interaction variables at baseline, 6 months (post-program), and 12 months (follow-up). Results All four dimensions of group cohesion had significant (ps group-interaction variables. Competition was a consistently strong predictor of cohesion, while cooperation did not demonstrate consistent patterns of prediction. Conclusions Facilitating a sense of friendly competition may increase engagement in physical activity programs by bolstering group cohesion. PMID:24779959

  12. Longitudinal analysis of minority women's perceptions of cohesion: the role of cooperation, communication, and competition. (United States)

    Harden, Samantha M; Estabrooks, Paul A; Mama, Scherezade K; Lee, Rebecca E


    Interaction in the form of cooperation, communication, and friendly competition theoretically precede the development of group cohesion, which often precedes adherence to health promotion programs. The purpose of this manuscript was to explore longitudinal relationships among dimensions of group cohesion and group-interaction variables to inform and improve group-based strategies within programs aimed at promoting physical activity. Ethnic minority women completed a group dynamics-based physical activity promotion intervention (N = 103; 73% African American; 27% Hispanic/Latina; mage = 47.89 + 8.17 years; mBMI = 34.43+ 8.07 kg/m2) and assessments of group cohesion and group-interaction variables at baseline, 6 months (post-program), and 12 months (follow-up). All four dimensions of group cohesion had significant (ps group-interaction variables. Competition was a consistently strong predictor of cohesion, while cooperation did not demonstrate consistent patterns of prediction. Facilitating a sense of friendly competition may increase engagement in physical activity programs by bolstering group cohesion.

  13. SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia. (United States)

    Paiva, Cody; Rowland, Taylor A; Sreekantham, Bhargava; Godbersen, Claire; Best, Scott R; Kaur, Prabhjot; Loriaux, Marc M; Spurgeon, Stephen E F; Danilova, Olga V; Danilov, Alexey V


    Although small molecule inhibitors of B-cell receptor-associated kinases have revolutionized therapy in chronic lymphocytic leukemia (CLL), responses are incomplete. Pro-survival signaling emanating from the microenvironment may foster therapeutic resistance of the malignant B cells resident in the protective lymphoid niches. B-cell activating factor (BAFF) is critical to the survival of both healthy and neoplastic B cells. However, the pro-survival pathways triggered by BAFF have not been fully characterized. Here we show that BAFF elicited resistance to spontaneous and drug-induced apoptosis in stromal co-cultures, induced activation of both canonical and non-canonical NFκB signaling pathways, and triggered B-cell receptor signaling in CLL cells, independently of IGHV mutational status. SYK, a proximal kinase in the B-cell receptor signaling cascade, acted via STAT3 to bolster transcription of the anti-apoptotic protein Mcl-1, thereby contributing to apoptosis resistance in BAFF-stimulated cells. SYK inhibitor entospletinib downregulated Mcl-1, abrogating BAFF-mediated cell survival. BAFF-B-cell receptor crosstalk in neoplastic B cells was mediated by SYK interaction with TRAF2/TRAF3 complex. Thus, SYK inhibition is a promising therapeutic strategy uniquely poised to antagonize crosstalk between BAFF and B-cell receptor, thereby disrupting the pro-survival microenvironment signaling in chronic lymphocytic leukemia. Copyright© Ferrata Storti Foundation.

  14. Thermokarst Characteristics and Distribution in a Transitional Arctic Biome: New Discoveries and Possible Monitoring Directions in a Climate Change Scenario (United States)

    Balser, A. W.; Gooseff, M. N.; Jones, J. B.; Bowden, W. B.; Sanzone, D. M.; Allen, A.; Larouche, J. R.


    In arctic regions, climate warming is leading to permafrost melting and wide-scale ecosystem alteration. A prominent pathway of permafrost loss is through thermokarst, which includes the catastrophic loss of soil structure and rapid subsidence. The regional-scale distribution of thermokarst is poorly documented throughout arctic regions. Remote landscapes and a lack of reliable, regional-scale detection techniques severely hamper our understanding of past prevalence and present distribution patterns. Intensive field campaigns are providing key data to bolster our understanding of the distribution and the characteristics of thermokarst formation, and enabling comprehensive method studies to develop remotely-sensed detection techniques. The Noatak Valley in northwestern Alaska's Brooks Range mountains harbors a transitional landscape from arctic and alpine tundra to boreal forest, all contained in a single 7,000,000 acre watershed. Preliminary field investigations augmented by photogrammetric measurements in 2006 revealed consistent patterns in the distribution of classifiable thermokarst feature types in a 2300 square-mile study area in the middle Noatak basin. Four distinct classes of thermokarst show remarkably tight relationships with ambient slope and local landcover. These investigations tie to larger efforts to document past and present regional distribution, testing remotely sensed data analysis techniques for baseline metrics and a future monitoring scheme.

  15. Can an active aging index (AAI) provide insight into reducing elder abuse? A case study in Rajshahi District, Bangladesh. (United States)

    Tareque, Md Ismail; Ahmed, Md Munsur; Tiedt, Andrew D; Hoque, Nazrul


    We use data from respondents aged 60 years and above, collected during April 2009 in the Rajshahi district of Bangladesh, to examine whether high activeness, as captured by an AAI or in sub-domains, can help reduce the risk of elder abuse. The findings suggest that more than half of rural elderly and 14 percent of urban elderly were at some point abused. High activeness in health and security dimensions lowers the risk of being abused while those who are low active in community participation have the lowest risk of being abused in both rural and urban areas. Being literate (elderly with primary/secondary education) is revealed to be a significant factor that lowers the risk of abuse in both rural and urban areas. These results imply a need for educational programs that bolster positive and proper community interaction, in turn promoting a secure later life for elders, and reducing burden for families and society. High activeness in health and security dimensions should also be promoted to keep the elderly healthy and protect from abusive behavior. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  16. How Bell Canada Capitalises on the Millennial: Affective Labour, Intersectional Identity, and Mental Health

    Directory of Open Access Journals (Sweden)

    Peters Meg


    Full Text Available Since 2010, the large telecommunications company, Bell Canada, has invited Canadians to “break the stigma” around mental illness through a campaign called #BellLetsTalk. The campaign claims to donate millions to mental health initiatives, aiming to also “start a conversation” about mental health online. In large part, the Bell Let’s Talk campaign depends on the position of the millennial as a social media user with a real stake in conversations revolving around mental health. I highlight how the term “mental health” is often correlated to normative affect and behaviour, pointing to the importance of an intersectional understanding of mental health. Colonialism is also at play here, as the Bell campaign donates to Indigenous communities, but fails to address how psychiatric intervention is often a colonial process in itself. Through a feminist and critical disability studies lens, I critique Bell for its seemingly apolitical ad campaign, arguing that it bolsters normative narratives around psychological distress and its place in neoliberal corporations and colonial Canada.

  17. Smart Growth and the Challenge of Nimby: Multifamily Dwellings and their Association with Single-Family House Selling Prices in Tallahasse, Florida, USA

    Directory of Open Access Journals (Sweden)

    Huston GIBSON


    Full Text Available Citizens protest development when they consider it undesirable. One type of development commonly perceived as undesirable by single-family home owners is proximate multifamily housing, often considered a cause of property devaluation. This study assesses multifamily housing, by typology, and its monetary association with proximate single-family housing prices. The research design is a cross-sectional study using multivariate regression. The unit of analysis is the detached single-family dwelling. The study population is a sample taken from all arms-length owner-occupied, primary residence, detached single-family property transactions recorded in Tallahassee-Leon County, Florida, USA, during 2008. The key findings show no statistically significant negative associations between multifamily housing and single-family property selling prices in the sample; in fact, the two were positively correlated. These findings address single-family homeowner concerns about proximate multifamily housing and should bolster the political feasibility of Smart Growth policy, which recommends denser urban infill.

  18. Operationalising emergency care delivery in sub-Saharan Africa: consensus-based recommendations for healthcare facilities. (United States)

    Calvello, Emilie J B; Tenner, Andrea G; Broccoli, Morgan C; Skog, Alexander P; Muck, Andrew E; Tupesis, Janis P; Brysiewicz, Petra; Teklu, Sisay; Wallis, Lee; Reynolds, Teri


    A major barrier to successful integration of acute care into health systems is the lack of consensus on the essential components of emergency care within resource-limited environments. The 2013 African Federation of Emergency Medicine Consensus Conference was convened to address the growing need for practical solutions to further implementation of emergency care in sub-Saharan Africa. Over 40 participants from 15 countries participated in the working group that focused on emergency care delivery at health facilities. Using the well-established approach developed in the WHO's Monitoring Emergency Obstetric Care, the workgroup identified the essential services delivered-signal functions-associated with each emergency care sentinel condition. Levels of emergency care were assigned based on the expected capacity of the facility to perform signal functions, and the necessary human, equipment and infrastructure resources identified. These consensus-based recommendations provide the foundation for objective facility capacity assessment in developing emergency health systems that can bolster strategic planning as well as facilitate monitoring and evaluation of service delivery. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

  19. Granulin Secreted by the Food-Borne Liver Fluke Opisthorchis viverrini Promotes Angiogenesis in Human Endothelial Cells

    Directory of Open Access Journals (Sweden)

    Brandon Haugen


    Full Text Available The liver fluke Opisthorchis viverrini is a food-borne, zoonotic pathogen endemic to Thailand and adjacent countries in Southeast Asia. The adult developmental stage of the O. viverrini parasite excretes and secretes numerous proteins within the biliary tract including the gall bladder. Lesions caused by the feeding activities of the liver fluke represent wounds that undergo protracted cycles of healing and re-injury during chronic infection, which can last for decades. Components of the excretory/secretory (ES complement released by the worms capably drive proliferation of bile duct epithelial cells and are implicated in establishing the oncogenic milieu that leads to bile duct cancer, cholangiocarcinoma. An ES protein, the secreted granulin-like growth factor termed Ov-GRN-1, accelerates wound resolution in mice and in vitro. To investigate angiogenesis (blood vessel development that may contribute to wound healing promoted by liver fluke granulin and, by implication, to carcinogenesis during chronic opisthorchiasis, we employed an in vitro tubule formation assay (TFA where human umbilical vein endothelial cells were grown on gelled basement matrix. Ten and 40 nM Ov-GRN-1 significantly stimulated angiogenesis as monitored by cellular proliferation and by TFA in real time. This demonstration of potent angiogenic property of Ov-GRN-1 bolsters earlier reports on the therapeutic potential for chronic non-healing wounds of diabetics, tobacco users, and the elderly and, in addition, showcases another of the hallmark of cancer characteristic of this carcinogenic liver fluke.

  20. An effective workplace stress management intervention: Chicken Soup for the Soul at Work Employee Groups. (United States)

    Horan, Anne Puidk


    Stress is a costly and significant source of health problems and mental distress--with work cited as a primary stressor. This pilot study supports the effectiveness of a new workplace stress intervention: Chicken Soup for the Soul at Work Employee Groups. In this program, employee-participants met during nine weekly meetings to read inspirational workplace stories, comment, and share their own stories. A leader, chosen from and by the group, guided meetings. Utilizing a wait-list control group design, participants were randomly assigned to an experimental or wait-list group. Participants completed pretests and posttests (Coping Resources Inventory, Occupational Stress Inventory-Revised, Job Descriptive Index, Pressure Management Indicator, survey). Statistical interaction effect for subtests was evaluated using a two-way repeated measures analysis of variance. Participants exhibited improved total coping resources, cognitive/rational coping, state of mind, confidence and home/work balance. Participant comments and their continued participation in a similar company-sponsored program bolster these empirical results.

  1. Relationship between a Centers for Disease Control and Prevention expanded HIV testing initiative and past-year testing by race/ethnicity: a multilevel analysis of the Behavioral Risk Factor Surveillance System. (United States)

    Gaines, Tommi L; Caldwell, Julia T; Ford, Chandra L; Mulatu, Mesfin S; Godette, Dionne C


    The Centers for Disease Control and Prevention's (CDC) expanded testing initiative (ETI) aims to bolster HIV testing among populations disproportionately affected by the HIV epidemic by providing additional funding to health departments serving these communities. ETI prioritizes testing in clinical settings; therefore, we examined the relationship between state-level ETI participation and past-year HIV testing among a racially/ethnically diverse sample of adult respondents to the 2012 Behavioral Risk Factor Surveillance System who accessed health services within the 12 months prior to being interviewed. Controlling for individual- and state-level characteristics in a multilevel logistic regression model, ETI participation was independently and positively associated with past-year testing, but this association varied by race/ethnicity. Hispanics had higher odds (adjusted odds ratio [AOR]: 1.49; 95% CI: 1.11-2.02) and American Indian/Alaska Natives had lower odds (AOR: 0.66; 95% CI: 0.43-0.99) of testing if they resided in states with (vs. without) ETI participation. State-level ETI participation did not significantly alter past-year testing among other racial/ethnic groups. Prioritizing public health resources in states most affected by HIV can improve testing patterns, but other mechanisms likely influence which racial/ethnic groups undergo testing.

  2. Do Smallholder, Mixed Crop-Livestock Livelihoods Encourage Sustainable Agricultural Practices? A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Thomas K. Rudel


    Full Text Available As calls for bolstering ecosystem services from croplands have grown more insistent during the past two decades, the search for ways to foster these agriculture-sustaining services has become more urgent. In this context we examine by means of a meta-analysis the argument, proposed by Robert McC. Netting, that small-scale, mixed crop-livestock farming, a common livelihood among poor rural peoples, leads to environmentally sustainable agricultural practices. As predicted, mixed crop-livestock farms exhibit more sustainable practices, but, contrary to predictions, a small scale of operation does not predict sustainability. Many smallholders on mixed crop-livestock farms use sustainable practices, but other smallholders practice a degrading, input-scarce agriculture. Some large farm operators use soil-conserving, minimum-tillage techniques while other large operators ignore soil-conserving techniques and practice an industrialized, high chemical input agriculture. The strength and pervasiveness of the link in the data between mixed crop-livestock farming and sustainable agricultural practices argues for agricultural policies that promote mixed crop-livestock livelihoods.

  3. Forecasting temporal dynamics of cutaneous leishmaniasis in Northeast Brazil.

    Directory of Open Access Journals (Sweden)

    Joseph A Lewnard


    Full Text Available Cutaneous leishmaniasis (CL is a vector-borne disease of increasing importance in northeastern Brazil. It is known that sandflies, which spread the causative parasites, have weather-dependent population dynamics. Routinely-gathered weather data may be useful for anticipating disease risk and planning interventions.We fit time series models using meteorological covariates to predict CL cases in a rural region of Bahía, Brazil from 1994 to 2004. We used the models to forecast CL cases for the period 2005 to 2008. Models accounting for meteorological predictors reduced mean squared error in one, two, and three month-ahead forecasts by up to 16% relative to forecasts from a null model accounting only for temporal autocorrelation.These outcomes suggest CL risk in northeastern Brazil might be partially dependent on weather. Responses to forecasted CL epidemics may include bolstering clinical capacity and disease surveillance in at-risk areas. Ecological mechanisms by which weather influences CL risk merit future research attention as public health intervention targets.

  4. Origins of food crops connect countries worldwide (United States)

    Achicanoy, Harold A.; Bjorkman, Anne D.; Navarro-Racines, Carlos; Guarino, Luigi; Flores-Palacios, Ximena; Engels, Johannes M. M.; Wiersema, John H.; Dempewolf, Hannes; Sotelo, Steven; Ramírez-Villegas, Julian; Castañeda-Álvarez, Nora P.; Fowler, Cary; Jarvis, Andy; Rieseberg, Loren H.; Struik, Paul C.


    Research into the origins of food plants has led to the recognition that specific geographical regions around the world have been of particular importance to the development of agricultural crops. Yet the relative contributions of these different regions in the context of current food systems have not been quantified. Here we determine the origins (‘primary regions of diversity’) of the crops comprising the food supplies and agricultural production of countries worldwide. We estimate the degree to which countries use crops from regions of diversity other than their own (‘foreign crops’), and quantify changes in this usage over the past 50 years. Countries are highly interconnected with regard to primary regions of diversity of the crops they cultivate and/or consume. Foreign crops are extensively used in food supplies (68.7% of national food supplies as a global mean are derived from foreign crops) and production systems (69.3% of crops grown are foreign). Foreign crop usage has increased significantly over the past 50 years, including in countries with high indigenous crop diversity. The results provide a novel perspective on the ongoing globalization of food systems worldwide, and bolster evidence for the importance of international collaboration on genetic resource conservation and exchange.

  5. Holocene history of drift ice in the northern North Atlantic: Evidence for different spatial and temporal modes (United States)

    Moros, M.; Andrews, John T.; Eberl, D.D.; Jansen, E.


    We present new high-resolution proxy data for the Holocene history of drift ice off Iceland based on the mineralogy of the <2-mm sediment fraction using quantitative X-ray diffraction. These new data, bolstered by a comparison with published proxy records, point to a long-term increasing trend in drift ice input into the North Atlantic from 6 to 5 ka toward the present day at sites influenced by the cold east Greenland Current. This feature reflects the late Holocene Neoglacial or cooling period recorded in ice cores and further terrestrial archives on Greenland. In contrast, a decrease in drift ice during the same period is recorded at sites underlying the North Atlantic Drift, which may reflect a warming of this region. The results document that Holocene changes in iceberg rafting and sea ice advection did not occur uniformly across the North Atlantic. Centennial-scale climate variability in the North Atlantic region over the last ???4 kyr is linked to the observed changes in drift ice input. Increased drift ice may have played a role in the increase of cold intervals during the late Holocene, e.g., the Little Ice Age cooling. Copyright 2006 by the American Geophysical Union.

  6. Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements (United States)

    Monroy, Guillermo L.; Won, Jungeun; Spillman, Darold R.; Dsouza, Roshan; Boppart, Stephen A.


    Since the inception of optical coherence tomography (OCT), advancements in imaging system design and handheld probes have allowed for numerous advancements in disease diagnostics and characterization of the structural and optical properties of tissue. OCT system developers continue to reduce form factor and cost, while improving imaging performance (speed, resolution, etc.) and flexibility for applicability in a broad range of fields, and nearly every clinical specialty. An extensive array of components to construct customized systems has also become available, with a range of commercial entities that produce high-quality products, from single components to full systems, for clinical and research use. Many advancements in the development of these miniaturized and portable systems can be linked back to a specific challenge in academic research, or a clinical need in medicine or surgery. Handheld OCT systems are discussed and explored for various applications. Handheld systems are discussed in terms of their relative level of portability and form factor, with mention of the supporting technologies and surrounding ecosystem that bolstered their development. Additional insight from our efforts to implement systems in several clinical environments is provided. The trend toward well-designed, efficient, and compact handheld systems paves the way for more widespread adoption of OCT into point-of-care or point-of-procedure applications in both clinical and commercial settings.

  7. Numerical and experimental modeling of liquid metal thin film flows in a quasi-coplanar magentic field

    Energy Technology Data Exchange (ETDEWEB)

    Morley, Neil B. [Univ. of California, Los Angeles, CA (United States)


    Liquid metal film protection of plasma-facing surfaces in fusion reactors is proposed in an effort to counter the adverse effects of high heat and particle fluxes from the burning plasma. Concerns still exist about establishing the required flow in presence of strong magnetic fields and plasma momentum flux typical of a reactor environment. In this work, the flow behavior of the film is examined under such conditions. Analysis of MHD equations as they apply to liquid metal flows with a free surface in the fully-developed limit was undertaken. Solution yields data for velocity profiles and uniform film heights vs key design parameters (channel size, magnetic field magnitude/orientation, channel slope, wall conductivity). These results are compared to previous models to determine accuracy of simplifying assumptions, in particular Hartmann averaging of films along {rvec B}. Effect of a plasma momentum flux on the thin films is also analyzed. The plasma momentum is strong enough in the cases examined to seriously upset the film, especially for lighter elements like Li. Ga performed much better and its possible use is bolstered by calculations. In an experiment in the MeGA-loop MHD facility, coplanar, wide film flow was found to be little affected by the magnetic field due to the elongated nature of the film. Both MHD drag and partial laminarization are observed, supporting the fully- developed film model predictions of the onset of MHD drag and duct flow estimations for flow laminarization.

  8. The Clinical Translation Gap in Child Health Exercise Research: A Call for Disruptive Innovation (United States)

    Ashish, Naveen; Bamman, Marcas M.; Cerny, Frank J.; D'Hemecourt, Pierre; Eisenmann, Joey C.; Ericson, Dawn; Fahey, John; Falk, Bareket; Gabriel, Davera; Kahn, Michael G.; Kemper, Han C.G.; Leu, Szu‐Yun; Liem, Robert I.; McMurray, Robert; Nixon, Patricia A.; Olin, J. Tod; Pianosi, Paolo T.; Purucker, Mary; Radom‐Aizik, Shlomit; Taylor, Amy


    Abstract In children, levels of play, physical activity, and fitness are key indicators of health and disease and closely tied to optimal growth and development. Cardiopulmonary exercise testing (CPET) provides clinicians with biomarkers of disease and effectiveness of therapy, and researchers with novel insights into fundamental biological mechanisms reflecting an integrated physiological response that is hidden when the child is at rest. Yet the growth of clinical trials utilizing CPET in pediatrics remains stunted despite the current emphasis on preventative medicine and the growing recognition that therapies used in children should be clinically tested in children. There exists a translational gap between basic discovery and clinical application in this essential component of child health. To address this gap, the NIH provided funding through the Clinical and Translational Science Award (CTSA) program to convene a panel of experts. This report summarizes our major findings and outlines next steps necessary to enhance child health exercise medicine translational research. We present specific plans to bolster data interoperability, improve child health CPET reference values, stimulate formal training in exercise medicine for child health care professionals, and outline innovative approaches through which exercise medicine can become more accessible and advance therapeutics across the broad spectrum of child health. PMID:25109386

  9. Examining the protective effects of mindfulness training on working memory capacity and affective experience. (United States)

    Jha, Amishi P; Stanley, Elizabeth A; Kiyonaga, Anastasia; Wong, Ling; Gelfand, Lois


    We investigated the impact of mindfulness training (MT) on working memory capacity (WMC) and affective experience. WMC is used in managing cognitive demands and regulating emotions. Yet, persistent and intensive demands, such as those experienced during high-stress intervals, may deplete WMC and lead to cognitive failures and emotional disturbances. We hypothesized that MT may mitigate these deleterious effects by bolstering WMC. We recruited 2 military cohorts during the high-stress predeployment interval and provided MT to 1 (MT, n = 31) but not the other group (military control group, MC, n = 17). The MT group attended an 8-week MT course and logged the amount of out-of-class time spent practicing formal MT exercises. The operation span task was used to index WMC at 2 testing sessions before and after the MT course. Although WMC remained stable over time in civilians (n = 12), it degraded in the MC group. In the MT group, WMC decreased over time in those with low MT practice time, but increased in those with high practice time. Higher MT practice time also corresponded to lower levels of negative affect and higher levels of positive affect (indexed by the Positive and Negative Affect Schedule). The relationship between practice time and negative, but not positive, affect was mediated by WMC, indicating that MT-related improvements in WMC may support some but not all of MT's salutary effects. Nonetheless, these findings suggest that sufficient MT practice may protect against functional impairments associated with high-stress contexts.

  10. A Longitudinal Experimental Study Comparing the Effectiveness of Happiness-Enhancing Strategies in Anglo Americans and Asian Americans (United States)

    Boehm, Julia K.; Lyubomirsky, Sonja; Sheldon, Kennon M.


    Growing evidence suggests that well-being interventions can be effective. However, it is unclear whether happiness-increasing practices are equally effective for individuals from different cultural backgrounds. To investigate this question, Anglo Americans and predominantly foreign-born Asian Americans were randomly assigned to express optimism, convey gratitude, or list their past experiences (control group). Multi-level analyses indicated that participants in the optimism and gratitude conditions reported enhanced life satisfaction relative to those in the control condition. However, Anglo Americans in the treatment conditions demonstrated larger increases in life satisfaction relative to Asian Americans, while both cultural groups in the control condition showed the least improvement. These results are consistent with the idea that the value individualist cultures place on self-improvement and personal agency bolsters the efforts of Anglo Americans to become more satisfied, whereas collectivist cultures’ de-emphasis of self-focus and individual goals interferes with the efforts of Asian Americans to pursue enhanced well-being. PMID:21432648

  11. Development and implementation of a screen-and-refer approach to addressing maternal depression, substance use, and intimate partner violence in home visiting clients. (United States)

    Dauber, Sarah; John, Tiffany; Hogue, Aaron; Nugent, Jessica; Hernandez, Gina


    Perinatal maternal depression (MD), substance use (SU), and intimate partner violence (IPV) are critical public health concerns with significant negative impacts on child development. Bolstering the capacity of home visiting (HV) programs to address these significant risk factors has potential to improve child and family outcomes. This study presents a description and mixed-methods feasibility evaluation of the "Home Visitation Enhancing Linkages Project (HELP)," a screen-and-refer approach to addressing MD, SU, and IPV within HV aimed at improving risk identification and linkage to treatment among HV clients. HELP was a three-phase intervention that included three evidence-based interventions: screening, motivational interviewing (MI), and case management (CM). This study presents quantitative fidelity data from 21 home visitors reporting on 116 clients in 4 HV programs, as well as qualitative data from structured interviews with 14 home visitors. Nearly all clients were screened and 22% screened positive on at least one risk domain. Rates of MI and CM implementation were lower than expected, however home visitors implemented general supportive interventions at high rates. Home visitor interviews revealed the following factors that may have impacted HELP implementation: client disclosure of risk, barriers to treatment access, systems integration, home visitor role perception, and integration of HELP into the broader HV curriculum. Implications of study findings for the design of future attempts to address maternal risk within HV are discussed.

  12. Larval development of Culex quinquefasciatus in water with low to moderate. (United States)

    Noori, Navideh; Lockaby, B Graeme; Kalin, Latif


    Population growth and urbanization have increased the potential habitats, and consequently the abundance of Culex quinquefasciatus, the southern house mosquito, a vector of West Nile Virus in urban areas. Water quality is critical in larval habitat distribution and in providing microbial food resources for larvae. A mesocosm experiment was designed to demonstrate which specific components of water chemistry are conducive to larval Culex mosquitoes. Dose-response relationships between larval development and NO3 , NH4 , and PO4 concentrations in stream water were developed through this experiment to describe the isolated effects of each nutrient on pre-adult development. The emergence pattern of Culex mosquitoes was found to be strongly related to certain nutrients, and results showed that breeding sites with higher PO4 or NO3 concentrations had higher larval survival rates. High NO3 concentrations favor the development of male mosquitoes and suppress the development of female mosquitoes, but those adult females that do emerge develop faster in containers with high NO3 levels compared to the reference group. The addition of PO4 in the absence of nitrogen sources to the larval habitat slowed larval development, however, it took fewer days for larvae to reach the pupal stage in containers with combinations of NO3 and PO4 or NH4 and PO4 nutrients. Results from this study may bolster efforts to control WNV in urban landscapes by exploring water quality conditions of Culex larval habitats that produce adult mosquitoes. © 2015 The Society for Vector Ecology.

  13. Lessons Learned From a Community–Academic Initiative: The Development of a Core Competency–Based Training for Community–Academic Initiative Community Health Workers (United States)

    Matos, Sergio; Kapadia, Smiti; Islam, Nadia; Cusack, Arthur; Kwong, Sylvia; Trinh-Shevrin, Chau


    Objectives. Despite the importance of community health workers (CHWs) in strategies to reduce health disparities and the call to enhance their roles in research, little information exists on how to prepare CHWs involved in community–academic initiatives (CAIs). Therefore, the New York University Prevention Research Center piloted a CAI–CHW training program. Methods. We applied a core competency framework to an existing CHW curriculum and bolstered the curriculum to include research-specific sessions. We employed diverse training methods, guided by adult learning principles and popular education philosophy. Evaluation instruments assessed changes related to confidence, intention to use learned skills, usefulness of sessions, and satisfaction with the training. Results. Results demonstrated that a core competency–based training can successfully affect CHWs’ perceived confidence and intentions to apply learned content, and can provide a larger social justice context of their role and work. Conclusions. This program demonstrates that a core competency–based framework coupled with CAI-research–specific skill sessions (1) provides skills that CAI–CHWs intend to use, (2) builds confidence, and (3) provides participants with a more contextualized view of client needs and CHW roles. PMID:22594730

  14. Confronting and resolving competing values behind conservation objectives. (United States)

    Karp, Daniel S; Mendenhall, Chase D; Callaway, Elizabeth; Frishkoff, Luke O; Kareiva, Peter M; Ehrlich, Paul R; Daily, Gretchen C


    Diverse motivations for preserving nature both inspire and hinder its conservation. Optimal conservation strategies may differ radically depending on the objective. For example, creating nature reserves may prevent extinctions through protecting severely threatened species, whereas incentivizing farmland hedgerows may benefit people through bolstering pest-eating or pollinating species. Win-win interventions that satisfy multiple objectives are alluring, but can also be elusive. To achieve better outcomes, we developed and implemented a practical typology of nature conservation framed around seven common conservation objectives. Using an intensively studied bird assemblage in southern Costa Rica as a case study, we applied the typology in the context of biodiversity's most pervasive threat: habitat conversion. We found that rural habitats in a varied tropical landscape, comprising small farms, villages, forest fragments, and forest reserves, provided biodiversity-driven processes that benefit people, such as pollination, seed dispersal, and pest consumption. However, species valued for their rarity, endemism, and evolutionary distinctness declined in farmland. Conserving tropical forest on farmland increased species that international tourists value, but not species discussed in Costa Rican newspapers. Despite these observed trade-offs, our analyses also revealed promising synergies. For example, we found that maintaining forest cover surrounding farms in our study region would likely enhance most conservation objectives at minimal expense to others. Overall, our typology provides a framework for resolving the competing objectives of modern conservation.

  15. The Role of International Human Rights Norms in the Liberalization of Abortion Laws Globally. (United States)

    Fine, Johanna B; Mayall, Katherine; Sepúlveda, Lilian


    International and regional human rights norms have evolved significantly to recognize that the denial of abortion care in a range of circumstances violates women's and girls' fundamental human rights. These increasingly progressive standards have played a critical role in transforming national-level abortion laws by both influencing domestic high court decisions on abortion and serving as a critical resource in advancing law and policy reform. Courts in countries such as Argentina, Bolivia, Brazil, Colombia, and Nepal have directly incorporated these standards into groundbreaking cases liberalizing abortion laws and increasing women's access to safe abortion services, demonstrating the influence of these human rights standards in advancing women's reproductive freedom. These norms have also underpinned national-level abortion law and policy reform, including in countries such as Spain, Rwanda, Uruguay, and Peru. As these human rights norms further evolve and increasingly recognize abortion as a human rights imperative, these standards have the potential to bolster transformative jurisprudence and law and policy reform advancing women's and girls' full reproductive autonomy.

  16. Validating indicators of treatment response: application to trichotillomania. (United States)

    Nelson, Samuel O; Rogers, Kate; Rusch, Natalie; McDonough, Lauren; Malloy, Elizabeth J; Falkenstein, Martha J; Banis, Maria; Haaga, David A F


    Different studies of the treatment of trichotillomania (TTM) have used varying standards to determine the proportion of patients who obtain clinically meaningful benefits, but there is little information on the similarity of results yielded by these methods or on their comparative validity. Data from a stepped-care (Step 1: Web-based self-help; Step 2: Individual behavior therapy; N = 60) treatment study of TTM were used to evaluate 7 potential standards: complete abstinence, ≥ 25% symptom reduction, recovery of normal functioning, and clinical significance (recovery + statistically reliable change), each of the last 3 being measured by self-report (Massachusetts General Hospital Hairpulling Scale; MGH-HPS) or interview (Psychiatric Institute Trichotillomania Scale). Depending on the metric, response rates ranged from 25 to 68%. All standards were significantly associated with one another, though less strongly for the 25% symptom reduction metrics. Concurrent (with deciding to enter Step 2 treatment) and predictive (with 3-month follow-up treatment satisfaction, TTM-related impairment, quality of life, and diagnosis) validity results were variable but generally strongest for clinical significance as measured via self-report. Routine reporting of the proportion of patients who make clinically significant improvement on the MGH-HPS, supplemented by data on complete abstinence, would bolster the interpretability of TTM treatment outcome findings. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  17. Ecological effects of nuclear steam electric station operations on estuarine systems. Final report

    International Nuclear Information System (INIS)

    Mihursky, J.A.


    This report summarizes the findings of studies of the impact of the Calvert Cliffs Nuclear Power Plant on the aquatic biota of Chesapeake Bay. Physical findings show that the typical radial extent of influence of the discharge on the physical and chemical environment of the Bay is rather limited (< 2 km). This suggestion is bolstered by findings of phytoplankton and zooplankton studies: when effects were noted at all, they only appeared at sampling stations nearest (within 2 km of) the discharge. Also, direct entrainment effects on these groups were either small (in the case of phytoplankton) or species-specific (in the case of zooplankton). Benthos showed mixed responses to plant operations - the populations of some species were enhanced, one species was adversely affected, and others were unaffected. The major plant effect on the benthos was due to habitat resource enrichment, and the consequence was higher standing stocks (e.g., more food for fish) in the affected area. Direct plant effects on finfish are dominated by impingement. Mortality as a result of impingement, for many species, tends to be moderate to slight. Effects as a result of entrainment of eggs and larvae are limited because the Calvert Cliffs area is not a major spawning location for any species. In sum, the Calvert Cliffs plant appears to have a limited effect on the Chesapeake Bay ecosystem. 180 references, 6 figures, 18 tables

  18. Engaging in an experiential processing mode increases positive emotional response during recall of pleasant autobiographical memories. (United States)

    Gadeikis, Darius; Bos, Nikita; Schweizer, Susanne; Murphy, Fionnuala; Dunn, Barnaby


    It is important to identify effective emotion regulation strategies to increase positive emotion experience in the general population and in clinical conditions characterized by anhedonia. There are indications that engaging in experiential processing (direct awareness of sensory and bodily experience) bolsters positive emotion experience but this has not been extensively tested during memory recall. To further test this notion, 99 community participants recalled two positive autobiographical memories. Prior to the second recall, participants either underwent an experiential, analytical, or distraction induction (n = 33 per condition). Subjective happiness and sadness ratings and heart rate variability (HRV) response were measured during each recall. Greater spontaneous use of experiential processing during the first memory was associated with greater happiness experience, but was unrelated to HRV and sadness experience. Inducing experiential processing increased happiness experience relative to both the analytical and distraction conditions (but had no impact on sadness experience). There was a significant difference in HRV between conditions. The experiential condition led to a trend-significant increase, and the other conditions a non-significant decrease, in HRV from the first to the second memory. These results suggest that engaging in experiential processing is an effective way to up-regulate positive emotion experience during positive memory recall. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  19. Neoliberal Policies and their Impact on Public Health Education: Observations on the Venezuelan Experience

    Directory of Open Access Journals (Sweden)

    Oscar Feo


    Full Text Available This article discusses the impact of neoliberal policies on the training of specialists in Public Health and describes the Venezuelan experience. In Venezuela, like other countries of the American continent, Public Health Schools had been transformed from institutions under the direction of the Ministry of Health to a model in which training took place under market conditions. Education in Public Health became a private good for individual consumption, and schools, lacking official funding, survived by offering courses in a market that did not necessarily respond to a country’s health needs. The conclusion discusses the currrent Venezuelan experience, in which the State has resumed control of the training of specialists in public health, making it more democratic, and adoptng an educational model centered around practice and whose purpose is the mass training of leadership teams to bolster the National Public Health System. In order to comment on the impact of neoliberal policies on training in public health we must first briefly review the following themes: 1. Basic concepts such as neoliberalism, globalization, and health systems. 2. The impact of neoliberal reforms on health. 3. The Venezuelan situation: basic principles for the training of professionals and technicians in health within the framework of a model of independent and sovereign national development. 4. Final reflections: challenges for the coming years.

  20. Mindfulness-Oriented Recovery Enhancement versus CBT for co-occurring substance dependence, traumatic stress, and psychiatric disorders: Proximal outcomes from a pragmatic randomized trial. (United States)

    Garland, Eric L; Roberts-Lewis, Amelia; Tronnier, Christine D; Graves, Rebecca; Kelley, Karen


    In many clinical settings, there is a high comorbidity between substance use disorders, psychiatric disorders, and traumatic stress. Novel therapies are needed to address these co-occurring issues efficiently. The aim of the present study was to conduct a pragmatic randomized controlled trial comparing Mindfulness-Oriented Recovery Enhancement (MORE) to group Cognitive-Behavioral Therapy (CBT) and treatment-as-usual (TAU) for previously homeless men residing in a therapeutic community. Men with co-occurring substance use and psychiatric disorders, as well as extensive trauma histories, were randomly assigned to 10 weeks of group treatment with MORE (n = 64), CBT (n = 64), or TAU (n = 52). Study findings indicated that from pre-to post-treatment MORE was associated with modest yet significantly greater improvements in substance craving, post-traumatic stress, and negative affect than CBT, and greater improvements in post-traumatic stress and positive affect than TAU. A significant indirect effect of MORE on decreasing craving and post-traumatic stress by increasing dispositional mindfulness was observed, suggesting that MORE may target these issues via enhancing mindful awareness in everyday life. This pragmatic trial represents the first head-to-head comparison of MORE against an empirically-supported treatment for co-occurring disorders. Results suggest that MORE, as an integrative therapy designed to bolster self-regulatory capacity, may hold promise as a treatment for intersecting clinical conditions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Examining the Role of Anxiety Sensitivity in Sleep Dysfunction Across Anxiety Disorders. (United States)

    Baker, Amanda W; Keshaviah, Aparna; Goetter, Elizabeth M; Bui, Eric; Swee, Michaela; Rosencrans, Peter L; Simon, Naomi M


    Anxiety Sensitivity (AS) has been associated with sleep difficulties in certain anxiety disorder populations, but no studies have examined cross-diagnostically the role of anxiety sensitivity in sleep dysfunction. Three hundred one participants with generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder (PD) completed an ancillary questionnaire-based study. Linear regression was used to examine AS and sleep dysfunction, and mediation analyses were used to examine whether AS was a mediator of the effect of primary diagnosis on sleep. AS was associated with increased sleep dysfunction across anxiety disorders, and primary anxiety disorder diagnosis was significantly associated with sleep dysfunction. However, after controlling for AS, primary diagnosis was no longer significant. AS significantly mediated the effects of PD versus SAD and of PD versus GAD on sleep dysfunction, but did not significantly mediate the effect of GAD versus SAD on sleep dysfunction. Taken together, AS appears to be a more important predictor of sleep dysfunction overall, emphasizing the cross-diagnostic nature of AS and bolstering the RDoC initiative approach for treating psychological dysfunction.

  2. Ties that bind: state policy and migrant female domestic helpers in Singapore. (United States)

    Huang, S; Yeoh, B S


    The introduction to this paper reviews the global economic restructuring that has led to theories of a new international division of labor (NIDL) marked by a global feminization of labor that exploits traditional feminine qualities. The argument is made that the NIDL theory fails to cover international labor migration such as that undertaken by female domestic servants in East and Southeast Asia. After summarizing recent research on international waged domestic labor, it is noted that policies of labor-sending countries have, until recently, reflected concerns with enhancing the flow of remittances home to relieve international debt rather than with the well-being of the workers. The paper goes on to focus on the effect of Singapore's state policies on incoming labor migration. After examining the conditions that created the demand for foreign maids, the paper investigates how state policy facilitated the exploitation of these women and perpetuated the social ideology of housework both as women's work and as non-work. It is shown that the official view that paid or unpaid productive labor belongs to the private domain beyond the purview of the state has detrimental repercussions for foreign domestic helpers. These arguments are bolstered with data from secondary sources and from field work conducted in 1995 involving a survey of 162 matched pairs of foreign domestic helpers and employers and in-depth interviews with 15 workers and 15 employers (13 matched pairs).

  3. Coral Bleaching Susceptibility Is Decreased following Short-Term (1–3 Year Prior Temperature Exposure and Evolutionary History

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    Joshua A. Haslun


    Full Text Available Coral exposed to short periods of temperature stress (≥1.0°C above mean monthly maximum and/or increased frequencies of high temperatures may bolster resilience to global warming associated with climate change. We compared Montastraea cavernosa (Linnaeus, 1767; Cnidaria, Scleractinia, Faviidae from the Florida Keys National Marine Sanctuary (FKNMS and the Flower Garden Banks National Marine Sanctuary (FGBNMS. Thermal stress has been reported frequently within the FKNMS; however, corals in the FGBNMS experience nominal exposures to similar stressors. Corals were exposed to three temperatures (27°C, 31°C, and 35°C for 72 h. Colonies from the FKNMS lost significantly fewer viable and necrotic zooxanthellae under conditions of acute stress (35°C than the FGBNMS colonies. This indicates that the FKNMS corals are less temperature-sensitive than those in the FGBNMS. The observed differences point to greater prior temperature exposure and adaptation in the former versus the latter site when correlated to previous years of thermal exposure.

  4. Bringing Back the Social Affordances of the Paper Memo to Aerospace Systems Engineering Work (United States)

    Davidoff, Scott; Holloway, Alexandra


    Model-based systems engineering (MBSE) is a relatively new field that brings together the interdisciplinary study of technological components of a project (systems engineering) with a model-based ontology to express the hierarchical and behavioral relationships between the components (computational modeling). Despite the compelling promises of the benefits of MBSE, such as improved communication and productivity due to an underlying language and data model, we observed hesitation to its adoption at the NASA Jet Propulsion Laboratory. To investigate, we conducted a six-month ethnographic field investigation and needs validation with 19 systems engineers. This paper contributes our observations of a generational shift in one of JPL's core technologies. We report on a cultural misunderstanding between communities of practice that bolsters the existing technology drag. Given the high cost of failure, we springboard our observations into a design hypothesis - an intervention that blends the social affordances of the narrative-based work flow with the rich technological advantages of explicit data references and relationships of the model-based approach. We provide a design rationale, and the results of our evaluation.

  5. search.bioPreprint: a discovery tool for cutting edge, preprint biomedical research articles [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Carrie L. Iwema


    Full Text Available The time it takes for a completed manuscript to be published traditionally can be extremely lengthy. Article publication delay, which occurs in part due to constraints associated with peer review, can prevent the timely dissemination of critical and actionable data associated with new information on rare diseases or developing health concerns such as Zika virus. Preprint servers are open access online repositories housing preprint research articles that enable authors (1 to make their research immediately and freely available and (2 to receive commentary and peer review prior to journal submission. There is a growing movement of preprint advocates aiming to change the current journal publication and peer review system, proposing that preprints catalyze biomedical discovery, support career advancement, and improve scientific communication. While the number of articles submitted to and hosted by preprint servers are gradually increasing, there has been no simple way to identify biomedical research published in a preprint format, as they are not typically indexed and are only discoverable by directly searching the specific preprint server websites. To address this issue, we created a search engine that quickly compiles preprints from disparate host repositories and provides a one-stop search solution. Additionally, we developed a web application that bolsters the discovery of preprints by enabling each and every word or phrase appearing on any web site to be integrated with articles from preprint servers. This tool, search.bioPreprint, is publicly available at

  6. Worldwide Engagement for Sustainable Energy Strategies

    Energy Technology Data Exchange (ETDEWEB)



    Almost 40 years after the Agency’s founding, the IEA responsibility for ensuring access to global oil supplies is still a core mandate. Yet over the course of its history, the IEA’s responsibilities have expanded along with both the international energy economy and conceptions of energy security itself. Our mission to promote secure and sustainable energy provision spans the energy mix. At the same time, a changing global energy map means that the industrialised nations of the world no longer dominate energy consumption. The IEA must work in close co-operation with partner countries and organisations worldwide to achieve its three core objectives: energy security, economic prosperity, and environmental sustainability. Working toward international commitments to reduce greenhouse gas emissions that cause global climate change; facilitating energy technology exchange, innovation and deployment; improving modern energy access to the billions of people who are without it; bolstering both cleanliness and security through energy efficiency; and promoting flexible and functioning energy markets – these efforts complement our traditional core responsibilities of mitigating the effects of supply disruptions and improving statistical transparency.

  7. Android Robot-Mediated Mock Job Interview Sessions for Young Adults with Autism Spectrum Disorder: A Pilot Study. (United States)

    Kumazaki, Hirokazu; Warren, Zachary; Corbett, Blythe A; Yoshikawa, Yuichiro; Matsumoto, Yoshio; Higashida, Haruhiro; Yuhi, Teruko; Ikeda, Takashi; Ishiguro, Hiroshi; Kikuchi, Mitsuru


    The feasibility and preliminary efficacy of an android robot-mediated mock job interview training in terms of both bolstering self-confidence and reducing biological levels of stress in comparison to a psycho-educational approach human interview was assessed in a randomized study. Young adults (ages 18-25 years) with autism spectrum disorder (ASD) were randomized to participate either in a mock job interview training with our android robot system ( n  = 7) or a self-paced review of materials about job-interviewing skills ( n  = 8). Baseline and outcome measurements of self-reported performance/efficacy and salivary cortisol were obtained after a mock job interview with a human interviewer. After training sessions, individuals with ASD participating in the android robot-mediated sessions reported marginally improved self-confidence and demonstrated significantly lower levels of salivary cortisol as compared to the control condition. These results provide preliminary support for the feasibility and efficacy of android robot-mediated learning.

  8. Gut microbiota-mediated protection against diarrheal infections. (United States)

    Vogt, Stefanie L; Finlay, B Brett


    The mammalian gut microbiota is a highly abundant and diverse microbial community that resides in the gastrointestinal tract. One major benefit that the gut microbiota provides to its host is colonization resistance-the ability to prevent colonization by foreign microbes, including diarrheal pathogens such as Clostridium difficile , Salmonella enterica serovar Typhimurium and diarrheagenic Escherichia coli . We conducted a literature review of the effects of the gut microbiota on infection by diarrheal pathogens. We used PubMed to search for relevant articles published before July 2016, as well as incorporated data from our laboratory. The gut microbiota provides protection from diarrheal infections both by direct inhibition of pathogens and by indirect effects on host functions. Direct effects of the microbiota on diarrheal pathogens include competing for nutrients and producing metabolites that inhibit pathogen growth or virulence. Indirect effects of the gut microbiota include promoting maintenance of the gut mucosal barrier and stimulating innate and adaptive immunity. Human epidemiological studies and experimental infections of laboratory animals both demonstrate that antibiotic treatment can alter the gut microbial community and thereby reduce colonization resistance against diarrheal pathogens. Further research might lead to the development of next-generation probiotics that could be used to bolster colonization resistance and thus prevent travellers' diarrheal.

  9. The Success of Linear Bootstrapping Models: Decision Domain-, Expertise-, and Criterion-Specific Meta-Analysis (United States)

    Kaufmann, Esther; Wittmann, Werner W.


    The success of bootstrapping or replacing a human judge with a model (e.g., an equation) has been demonstrated in Paul Meehl’s (1954) seminal work and bolstered by the results of several meta-analyses. To date, however, analyses considering different types of meta-analyses as well as the potential dependence of bootstrapping success on the decision domain, the level of expertise of the human judge, and the criterion for what constitutes an accurate decision have been missing from the literature. In this study, we addressed these research gaps by conducting a meta-analysis of lens model studies. We compared the results of a traditional (bare-bones) meta-analysis with findings of a meta-analysis of the success of bootstrap models corrected for various methodological artifacts. In line with previous studies, we found that bootstrapping was more successful than human judgment. Furthermore, bootstrapping was more successful in studies with an objective decision criterion than in studies with subjective or test score criteria. We did not find clear evidence that the success of bootstrapping depended on the decision domain (e.g., education or medicine) or on the judge’s level of expertise (novice or expert). Correction of methodological artifacts increased the estimated success of bootstrapping, suggesting that previous analyses without artifact correction (i.e., traditional meta-analyses) may have underestimated the value of bootstrapping models. PMID:27327085

  10. Unemployment, public-sector healthcare spending and stomach cancer mortality in the European Union, 1981-2009. (United States)

    Maruthappu, Mahiben; Painter, Annabelle; Watkins, Johnathan; Williams, Callum; Ali, Raghib; Zeltner, Thomas; Faiz, Omar; Sheth, Hemant


    We sought to determine the association between changes in unemployment, healthcare spending and stomach cancer mortality. Multivariate regression analysis was used to assess how changes in unemployment and public-sector expenditure on healthcare (PSEH) varied with stomach cancer mortality in 25 member states of the European Union from 1981 to 2009. Country-specific differences in healthcare infrastructure and demographics were controlled for 1- to 5-year time-lag analyses and robustness checks were carried out. A 1% increase in unemployment was associated with a significant increase in stomach cancer mortality in both men and women [men: coefficient (R)=0.1080, 95% confidence interval (CI)=0.0470-0.1690, P=0.0006; women: R=0.0488, 95% CI=0.0168-0.0809, P=0.0029]. A 1% increase in PSEH was associated with a significant decrease in stomach cancer mortality (men: R=-0.0009, 95% CI=-0.0013 to -0.005, Peconomic factors, urbanization, nutrition and alcohol intake were controlled for, but not when healthcare resources were controlled for. Time-lag analysis showed that the largest changes in mortality occurred 3-4 years after any changes in either unemployment or PSEH. Increases in unemployment are associated with a significant increase in stomach cancer mortality. Stomach cancer mortality is also affected by public-sector healthcare spending. Initiatives that bolster employment and maintain public-sector healthcare expenditure may help to minimize increases in stomach cancer mortality during economic downturns.

  11. Back to the Future: The Potential of Intergenerational Justice for the Achievement of the Sustainable Development Goals

    Directory of Open Access Journals (Sweden)

    Rita Vasconcellos Oliveira


    Full Text Available The establishment of the UN Sustainable Development Goals (SDGs bolstered momentum to achieve a sustainable future. Undeniably, the welfare of future generations is a fundamental value of sustainable development since the publication of the Brundtland report. Nevertheless, SDGs and their targets are meagre on intergenerational justice concerns. The 15-year target horizon of the SDGs might be beneficial for implementation reasons. However, such a short-term perspective is far from innocuous in justice terms. It jeopardises the establishment of long-term goals, which protect both present and future people. This article advocates for clearer stances on intergenerational justice. What type of distributive principles could and should dictate the present socio-economic development? Looking at intragenerational justice principles contained in SDGs does not provide a full answer since they express conflicting visions of what constitutes a fair development. Furthermore, a fair distribution of the development benefits and burdens among present and near future people does not necessarily guarantee the wellbeing of more distant generations. I propose an intergenerational sufficientarian perspective as a way of extending the beneficial impacts of SDGs to both close and distant future generations. Hopefully, it facilitates the translation of the SDGs into policies that promote fairer implementation strategies.

  12. Taming a wandering attention: short-form mindfulness training in student cohorts. (United States)

    Morrison, Alexandra B; Goolsarran, Merissa; Rogers, Scott L; Jha, Amishi P


    Mindfulness training (MT) is a form of mental training in which individuals engage in exercises to cultivate an attentive, present centered, and non-reactive mental mode. The present study examines the putative benefits of MT in University students for whom mind wandering can interfere with learning and academic success. We tested the hypothesis that short-form MT (7 h over 7 weeks) contextualized for the challenges and concerns of University students may reduce mind wandering and improve working memory. Performance on the sustained attention to response task (SART) and two working memory tasks (operation span, delayed-recognition with distracters) was indexed in participants assigned to a waitlist control group or the MT course. Results demonstrated MT-related benefits in SART performance. Relative to the control group, MT participants had higher task accuracy and self-reported being more "on-task" after the 7-week training period. MT did not significantly benefit the operation span task or accuracy on the delayed-recognition task. Together these results suggest that while short-form MT did not bolster working memory task performance, it may help curb mind wandering and should, therefore, be further investigated for its use in academic contexts.

  13. Taming a Wandering Attention: Short-Form Mindfulness Training in Student Cohorts

    Directory of Open Access Journals (Sweden)

    Alexandra B. Morrison


    Full Text Available Mindfulness training (MT is a form of mental training in which individuals engage in exercises to cultivate an attentive, present centered, and non-reactive mental mode. The present study examines the putative benefits of MT in University students for whom mind wandering can interfere with learning and academic success. We tested the hypothesis that short-form MT (7 hours over 7 weeks contextualized for the challenges and concerns of University students may reduce mind wandering and improve working memory. Performance on the sustained attention response task (SART and two working memory tasks (operation span, delayed-recognition with distracters was indexed in participants assigned to a waitlist control group or the MT course. Results demonstrated MT-related benefits in SART performance. Relative to the control group, MT participants had higher task accuracy and self-reported being more on-task after the 7-week training period. MT did not significantly benefit the operation span task or accuracy on the delayed-recognition task. Together these results suggest that while short-form MT did not bolster working memory task performance, it may help curb mind wandering and should, therefore, be further investigated for its use in academic contexts.

  14. Revisiting the Diego Blood Group System in Amerindians: Evidence for Gene-Culture Comigration.

    Directory of Open Access Journals (Sweden)

    Christophe Bégat

    Full Text Available Six decades ago the DI*A allele of the Diego blood group system was instrumental in proving Native American populations originated from Siberia. Since then, it has received scant attention. The present study was undertaken to reappraise distribution of the DI*A allele in 144 Native American populations based on current knowledge. Using analysis of variance tests, frequency distribution was studied according to geographical, environmental, and cultural parameters. Frequencies were highest in Amazonian populations. In contrast, DI*A was undetectable in subarctic, Fuegian, Panamanian, Chaco and Yanomama populations. Closer study revealed a correlation that this unequal distribution was correlated with language, suggesting that linguistic divergence was a driving force in the expansion of DI*A among Native Americans. The absence of DI*A in circumpolar Eskimo-Aleut and Na-Dene speakers was consistent with a late migratory event confined to North America. Distribution of DI*A in subtropical areas indicated that gene and culture exchanges were more intense within than between ecozones. Bolstering the utility of classical genetic markers in biological anthropology, the present study of the expansion of Diego blood group genetic polymorphism in Native Americans shows strong evidence of gene-culture comigration.

  15. Death, time and the theory of relativity. (United States)

    Chochinov, Harvey Max


    Many people believe that spending large amounts of money on end-of-life care is unjustified and even irrational. This fails to recognize that the value of time, particularly quality time, appears to increase as death draws near. Paying for treatment that merely allows patients and families to avoid confronting the inevitability of death is wrong. However, palliative care, which can bolster the quality of a patient's remaining days, provides benefits that extend to the family and beyond. How can the notion of time gaining value toward the end of life be incorporated into conventional cost-benefit analyses? A standard QALY (Quality Adjusted Life Years) is the product of quality of life and time, without adjusting for any change in the value of time. An additional variable--a Valuation Index (Palliative) (or VIP)--needs to be factored into the equation, providing a rational explanation for what otherwise might be deemed irrational spending. When one recognizes the multitude of important things that happen as people approach the very end of life, the numbers start to add up. Copyright © 2011 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.

  16. A New Spin on Photoemission Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Jozwiak, Chris [Univ. of California, Berkeley, CA (United States)


    The electronic spin degree of freedom is of general fundamental importance to all matter. Understanding its complex roles and behavior in the solid state, particularly in highly correlated and magnetic materials, has grown increasingly desirable as technology demands advanced devices and materials based on ever stricter comprehension and control of the electron spin. However, direct and efficient spin dependent probes of electronic structure are currently lacking. Angle Resolved Photoemission Spectroscopy (ARPES) has become one of the most successful experimental tools for elucidating solid state electronic structures, bolstered by-continual breakthroughs in efficient instrumentation. In contrast, spin-resolved photoemission spectroscopy has lagged behind due to a lack of similar instrumental advances. The power of photoemission spectroscopy and the pertinence of electronic spin in the current research climate combine to make breakthroughs in Spin and Angle Resolved Photoemission Spectroscopy (SARPES) a high priority . This thesis details the development of a unique instrument for efficient SARPES and represents a radical departure from conventional methods. A custom designed spin polarimeter based on low energy exchange scattering is developed, with projected efficiency gains of two orders of magnitude over current state-of-the-art polarimeters. For energy analysis, the popular hemispherical analyzer is eschewed for a custom Time-of-Flight (TOF) analyzer offering an additional order of magnitude gain in efficiency. The combined instrument signifies the breakthrough needed to perform the high resolution SARPES experiments necessary for untangling the complex spin-dependent electronic structures central to today's condensed matter physics.

  17. The power of the past: nostalgia as a meaning-making resource. (United States)

    Routledge, Clay; Wildschut, Tim; Sedikides, Constantine; Juhl, Jacob; Arndt, Jamie


    In three experiments we tested whether nostalgia bolsters meaning in life relative to two other modes of autobiographical thought: imagining a desired future experience and recalling a positive past experience. In Experiment 1 participants thought about a nostalgic or desired future experience and then completed a presence of meaning scale. Thinking about a nostalgic (compared to desired future) experience increased perceived presence of meaning. In Experiment 2 we examined whether nostalgia can additionally reduce the search for meaning. Participants thought about a nostalgic, desired future or recent positive experience, and then completed a search for meaning scale. Nostalgia, relative to both comparison conditions, decreased the search for meaning. Finally we tested whether, by virtue of its capacity to increase meaning, nostalgia can mitigate threats to meaning. In Experiment 3 participants were exposed to either absurd or representational art, under the guise that they would later have to interpret its meaning, and then thought about either a nostalgic or a recent positive experience. Meaning was subsequently measured. The absurd art interpretation condition decreased the perceived presence of meaning but nostalgic reflection attenuated this effect.

  18. Nostalgia-Evoked Inspiration: Mediating Mechanisms and Motivational Implications. (United States)

    Stephan, Elena; Sedikides, Constantine; Wildschut, Tim; Cheung, Wing-Yee; Routledge, Clay; Arndt, Jamie


    Six studies examined the nostalgia-inspiration link and its motivational implications. In Study 1, nostalgia proneness was positively associated with inspiration frequency and intensity. In Studies 2 and 3, the recollection of nostalgic (vs. ordinary) experiences increased both general inspiration and specific inspiration to engage in exploratory activities. In Study 4, serial mediational analyses supported a model in which nostalgia increases social connectedness, which subsequently fosters self-esteem, which then boosts inspiration. In Study 5, a rigorous evaluation of this serial mediational model (with a novel nostalgia induction controlling for positive affect) reinforced the idea that nostalgia-elicited social connectedness increases self-esteem, which then heightens inspiration. Study 6 extended the serial mediational model by demonstrating that nostalgia-evoked inspiration predicts goal pursuit (intentions to pursue an important goal). Nostalgia spawns inspiration via social connectedness and attendant self-esteem. In turn, nostalgia-evoked inspiration bolsters motivation. © 2015 by the Society for Personality and Social Psychology, Inc.

  19. Conceptual Perspectives: Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human Host

    Directory of Open Access Journals (Sweden)

    Santosh K. Ghosh


    Full Text Available Human beta defensins (hBDs are small cationic peptides, expressed in mucosal epithelia and important agents of innate immunity, act as antimicrobial and chemotactic agents at mucosal barriers. In this perspective, we present evidence supporting a novel strategy by which the oral bacterium Fusobacterium nucleatum induces hBDs and other antimicrobial peptides (AMPs in normal human oral epithelial cells (HOECs and thereby protects them from other microbial pathogens. The findings stress (1 the physiological importance of hBDs, (2 that this strategy may be a mechanism that contributes to homeostasis and health in body sites constantly challenged with bacteria and (3 that novel properties identified in commensal bacteria could, one day, be harnessed as new probiotic strategies to combat colonization of opportunistic pathogens. With that in mind, we highlight and review the discovery and characterization of a novel lipo-protein, FAD-I (FusobacteriumAssociated Defensin Inducer associated with the outer membrane of F. nucleatum that may act as a homeostatic agent by activating endogenous AMPs to re-equilibrate a dysregulated microenvironment. FAD-I has the potential to reduce dysbiosis-driven diseases at a time when resistance to antibiotics is increasing. We therefore postulate that FAD-I may offer a new paradigm in immunoregulatory therapeutics to bolster host innate defense of vulnerable mucosae, while maintaining physiologically responsive states of inflammation.

  20. Technology transfer of oil-in-water emulsion adjuvant manufacturing for pandemic influenza vaccine production in Romania. (United States)

    Fox, Christopher B; Huynh, Chuong; O'Hara, Michael K; Onu, Adrian


    Many developing countries lack or have inadequate pandemic influenza vaccine manufacturing capacity. In the 2009 H1N1 pandemic, this led to delayed and inadequate vaccine coverage in the developing world. Thus, bolstering developing country influenza vaccine manufacturing capacity is urgently needed. The Cantacuzino Institute in Bucharest, Romania has been producing seasonal influenza vaccine since the 1970s, and has the capacity to produce ∼5 million doses of monovalent vaccine in the event of an influenza pandemic. Inclusion of an adjuvant in the vaccine could enable antigen dose sparing, expanding vaccine coverage and potentially allowing universal vaccination of the Romanian population and possibly neighboring countries. However, adjuvant formulation and manufacturing know-how are difficult to access. This manuscript describes the successful transfer of oil-in-water emulsion adjuvant manufacturing and quality control technologies from the Infectious Disease Research Institute in Seattle, USA to the Cantacuzino Institute. By describing the challenges and accomplishments of the project, it is hoped that the knowledge and experience gained will benefit other institutes involved in similar technology transfer projects designed to facilitate increased vaccine manufacturing capacity in developing countries. Copyright © 2012 Elsevier Ltd. All rights reserved.