WorldWideScience

Sample records for bolsters

  1. FDA Bolsters Warnings about Class of Antibiotics

    Science.gov (United States)

    ... html FDA Bolsters Warnings About Class of Antibiotics Fluoroquinolones such as Cipro, Levaquin should be reserved for ... label warnings on a class of antibiotics called fluoroquinolones because the drugs can lead to disabling side ...

  2. Dengue Virus May Bolster Zika's Attack

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_159534.html Dengue Virus May Bolster Zika's Attack Prior exposure to ... 23, 2016 (HealthDay News) -- Prior exposure to the dengue fever virus may increase the severity of Zika ...

  3. Mechanically Powered Negative Pressure Wound Therapy as a Bolster for Skin Grafting

    Directory of Open Access Journals (Sweden)

    Adam L. Isaac, DPM

    2014-02-01

    Full Text Available Summary: The use of negative pressure wound therapy (NPWT as a bolster for split-thickness skin grafts has been well documented in the literature. It facilitates the removal of transudate, which can result in the formation of seroma, and mitigates shear stress, which can detach the graft from the underlying wound bed. Its widespread use may be limited by factors such as increased cost and length of hospitalization. Recently, mechanically powered devices (Smart Negative Pressure; Spiracur, Inc., Sunnyvale, Calif. have been reported as showing promise in healing wounds with outcomes surprisingly comparable to standard NPWT in the populations studied. We are unaware of any reports in the literature that have detailed the use of a mechanically powered NPWT device as a postoperative bolster for split-thickness skin grafts.

  4. Mechanically Powered Negative Pressure Wound Therapy as a Bolster for Skin Grafting

    OpenAIRE

    Adam L. Isaac, DPM; Jessica Rose, DO; David G. Armstrong, DPM, MD, PhD

    2014-01-01

    Summary: The use of negative pressure wound therapy (NPWT) as a bolster for split-thickness skin grafts has been well documented in the literature. It facilitates the removal of transudate, which can result in the formation of seroma, and mitigates shear stress, which can detach the graft from the underlying wound bed. Its widespread use may be limited by factors such as increased cost and length of hospitalization. Recently, mechanically powered devices (Smart Negative Pressure; Spiracur, In...

  5. The Role of Bolstering and Counterarguing Mind-Sets in Persuasion

    OpenAIRE

    Alison Jing Xu; Robert S. Wyer Jr.

    2012-01-01

    The effect of a persuasive communication on individuals' attitudes can be influenced by the cognitive behavior they have performed in an earlier, unrelated situation. Inducing participants to make supportive elaborations about a series of propositions activated a bolstering mind-set that increased the effectiveness of an unrelated advertisement they encountered subsequently. However, inducing participants to refute the implications of a series of propositions activated a counterarguing mind-s...

  6. Research and Teaching: Think before (and after) You Speak: Practice and Self-Reflection Bolster Oral Communication Skills

    Science.gov (United States)

    Sterling, Eleanor; Bravo, Adriana; Porzecanski, Ana Luz; Burks, Romi L.; Linder, Joshua; Langen, Tom; Fernandez, Denny; Ruby, Douglas; Bynum, Nora

    2016-01-01

    In this study, conservation biology faculty and practitioners from across the United States designed classroom exercises and teaching interventions intended to bolster oral communication skills. Through repeated oral presentation assignments integrated into course requirements, the authors examined individual student learning gains via…

  7. The effect of prone positioning with surgical bolsters on liver blood flow in healthy volunteers.

    Science.gov (United States)

    Chikhani, M; Evans, D L; Blatcher, A W; Jackson, A P; Guha, I N; Aithal, G P; Moppett, I K

    2016-05-01

    This study sought to identify changes in hepatic flood flow and cardiac output during prone positioning on surgical bolsters in awake volunteers, and was prompted by a local incident of significant hepatic dysfunction following surgery in the prone position. Cardiac output was determined using the non-invasive Peñáz technique, and plasma disappearance rate of indocyanine green (ICG-PDR) was measured as a surrogate maker for hepatic blood flow along with serum hepatic enzyme assays. Measurements were made after one hour in supine, prone and returned supine positions. Ten volunteers completed the study. There were significant changes in the disappearance rate of indocyanine green, which decreased this from mean (SD) 31.1 (9.70) supine to 19.6 (4.37)%.min prone, respectively (p = 0.02), increasing on return to the supine position to 24.6 (5.54)%.min (p = 0.019). Cardiac output was also significantly reduced when changing from the supine to the prone position, from mean (SD) 4.7 (1.0 to 3.5 (1.1) (l.min(-1) ), respectively (p = 0.002). We demonstrated an acute and reversible change in both hepatocellular function and cardiac output associated with the prone position. PMID:26948476

  8. Moderating Risks, Bolstering Growth

    OpenAIRE

    World Bank

    2012-01-01

    Half a year ago, Russia's economic prospects looked uncertain. The global economy was losing momentum, the expansion in the euro area was grinding to a halt and commodity prices were beginning to fall. Yet, while output growth is slowing this year in line with weaker growth in Europe and elsewhere, Russia's latest economy performance has been solid, though aided by favorable oil prices. Th...

  9. Idelalisib Bolsters CLL Regimen.

    Science.gov (United States)

    2016-03-01

    Idelalisib enhances the effectiveness of bendamustine and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia. The addition of idelalisib increased progression-free survival in these patients from 11 months to 23 months, but it also increased the incidence of side effects. PMID:26772993

  10. A Potential of Rail Vehicle Having Bolster with Side Bearers for Improving Curving Performance on Sharp Curves Employing Link-Type Forced Steering Mechanism

    Science.gov (United States)

    Tanifuji, Katsuya; Yaegashi, Naoki; Soma, Hitoshi

    The air spring of bolsterless bogie trucks, which have been widely employed in railway vehicles in recent years, undergoes a large distortion when the vehicles negotiate sharp curves in lines such as subway lines, and this can deteriorate the durability of air springs. Furthermore, bolsterless trucks tend to suffer from increased wheel lateral force around sharp curves with a radius of 100 m or less. In this paper we discuss the application of a link-type forced steering mechanism to bogie trucks with a bolster as a countermeasure against the above-mentioned situation. A numerical simulation is carried out using a MBS software, SIMPACK. As a result, under the condition of reduced longitudinal stiffness in the primary suspension, a bolster truck with the link-type steering mechanism exhibits the potential to suppress the wheel lateral force occurring around sharp curves. Also, the deterioration in running stability due to the application of the steering mechanism can be recovered by adding moderate lateral damping in the secondary suspension. In addition, the obtained wear index shows that the forced steering truck has decreased flange wear resulting from passing through sharp curves.

  11. Landsat helps bolster food security

    Science.gov (United States)

    U.S. Geological Survey

    2016-01-01

    One of the cruelest, most complex narratives in the world today (2016) is written in the hunger of sub-Saharan Africa. When famine is the only yield from the scorched Earth, survival often depends on a heart-rending calculation—how far is the distant feeding center; how close is the nearest well.

  12. China to Bolster Oil Stockpiles

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ China is accelerating the build-up of its oil reserves to avoid the economic dislocations the country suffered in 2008 from fluctuations in the world oil price.China will,in addition to the current four strategic petroleum reserve bases,build eight new ones by 2011.The program will increase China's strategic crude reserve capacity to 44.6 million cubic meters,or 281 million barrels.The country will also increase its oil products reserve to 10 million tons by 2011."China's attentiveness to its oil reserve capacity has grown in tandem with its rising dependence on imported oil," said Pan Jiahua,an expert with the Chinese petroleum society.

  13. New TRIUMF bolsters Canadian physics

    CERN Document Server

    Gwynne, P

    2001-01-01

    Alan Shotter has been appointed director of TRIUMF. The ISAC accelerator there will be used to simulate astrophysical phenomena but the director will also be looking at ways to expand the research programme into other areas (1/2 page).

  14. Child Care Gifts to Bolster Astronomy

    Science.gov (United States)

    Nemiroff, Robert J.; Allen, Alice

    2016-01-01

    Caring for children should not derail potentially excellent future astronomers. It is therefore suggested that a mechanism be created for established astronomers to voluntarily will 10 percent of their estate to a fund that helps aspiring astronomers reduce child care costs. Statistics indicate that many scientists delay child rearing until they have secure jobs. This delay appears to be based on the early relative cost of child care and the perception that time spent raising children negatively impacts job performance and future employability. Having even a portion of child care expenses covered may increase the efficiency of early-career education and productivity of early-career scientific research. It is hoped that some established astronomers may be inspired to contribute by remembering their own lives as aspiring astronomers, while also wishing to add to their legacy. Only an expression of interest is requested here, both from established astronomers who might be interested in taking such a donation pledge, and from aspiring astronomers who feel their careers would be helped by child care assistance.

  15. Bolstering the U.S.Middle Class

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Making every attempt to boost the sluggish U.S.economy, U.S.President Barack Obama has pledged incentive programs including tax cuts for the middle class that have "for generations,made our economy the envy of the world." But the program may not be a panacea as income inequality in the United States becomes entrenched.Zhang Monan,a researcher with the State Information Center,discussed this issue in an article recently published in the China Securities Journal.Edited excerpts follow.

  16. Russian energy in the EU market: Bolstered institutionsand their effects

    International Nuclear Information System (INIS)

    The article examines institutional changes in EU–Russian energy relations since 2000. The article explores the ability of transformed institutions to limit the politicisation of energy and to reconcile the EU competitive-market approach with Russian state capitalism. More specifically, the article focuses on changes in intergovernmental, transgovernmental and transnational interactions. The article demonstrates that the gradual strengthening of transgovernmental and transnational institutions has inhibited the politicisation of energy relations and facilitated regulative cooperation between the EU and Russia. However, the potential of shared institutions is constrained by internal institutions on both sides. In Russia, these obstacles are insufficient top-down delegation of responsibilities in the government and its great power aspirations. In the EU, key barriers include inter-institutional rivalries, the EU’s propensity to impose its legislation on external partners and the integration of energy policy with foreign policy. The article presents several policy implications. First, it is futile to institutionally impose the regulative paradigm of one partner on the other; rather, mutual dialogue is needed. Thus, institutions should be structured appropriately. Second, current depoliticisation will require the involvement of not only the EU and Russia but also transit countries, such as Ukraine. Third, transgovernmental and transnational cooperation should be nurtured because this is a useful channel for both information exchange and a regulative convergence of policy implementing mechanisms. Finally, this incremental regulative convergence is the only option available today for the EU and Russia; this is also a way to further depoliticise energy relations. - Highlights: • EU and Russia developed transgovernmental and transnational energy institutions. • It allowed them to face energy challenges: depoliticisation and market construction. • Internal EU and Russian institutions act as constraints. • Institutions have to marry Russia's state capitalism and EU competitive markets. • Transgovernmental and transnational institutions are to be further promoted

  17. Pedagogical Stressors and Coping Strategies for Bolstering Teacher Resilience

    Science.gov (United States)

    Moore, Reginald L.

    2013-01-01

    Teacher emotional exhaustion or burnout is a problem for local pubic educators because many teachers do not stay in the profession long enough to become experienced in the classroom. The purpose of this study was to identify practices that assist teachers in overcoming emotional exhaustion related to their profession. Guided by resilience theory,…

  18. Surging electricity demand growth bolsters outlook for natural gas

    International Nuclear Information System (INIS)

    Economic expansion and regulatory reform are combining to boost global opportunities for burning gas to generate electric power. Companies producing, marketing, or transporting gas are capitalizing on the improved outlook by seizing on synergistic roles in the power generation chain. Much of the improved outlook for gas stems from projected hearty increases in global demand for electricity. Bechtel Power Corp., estimates global power generation capacity during 1994--2003 will increase to as much as 1.2 billion kw, about 25% of which could be added by independent power production (IPPs). Since about 200 bcf of gas reserves producing about 20 MMcfd of gas is needed to fuel of a 100,000 kw electric generating station for 25 years, that adds up to a major growth opportunity for gas producers. The paper discusses the assessment of gas reserves, US power growth, the intent of the Energy Policy Act of 1992 (Epact), effects of Epact, gas industry response, power marketing units, synergistic possibilities, effects on US utilities, international power imperatives, non-US projects, funding good projects, and forecasting future developments

  19. Time will tell: resource continuity bolsters ecosystem services.

    Science.gov (United States)

    Schellhorn, Nancy A; Gagic, Vesna; Bommarco, Riccardo

    2015-09-01

    A common suggestion to support ecosystem services to agriculture provided by mobile organisms is to increase the amount of natural and seminatural habitat in the landscape. This might, however, be inefficient, and demands for agricultural products limit the feasibility of converting arable land into natural habitat. To develop more targeted means to promote ecosystem services, we need a solid understanding of the limitations to population growth for service-providing organisms. We propose a research agenda that identifies resource bottlenecks and interruptions over time to key beneficial organisms, emphasising their resulting population dynamics. Targeted measures that secure the continuity of resources throughout the life cycle of service-providing organisms are likely to effectively increase the stock, flow, and stability of ecosystem services. PMID:26138384

  20. Survey Says: Using Teacher Feedback to Bolster Evaluation

    Science.gov (United States)

    Wiener, Ross; Lundy, Kasia

    2014-01-01

    Many of the leading private sector organizations have for years embraced a survey approach to improving products, services, and internal policies and processes. Like these successful private sector businesses, school systems can utilize a similar survey-based approach to improving teacher evaluation. Here, the authors provide and outline some…

  1. Bolstering the Impact of Online Professional Development for Teachers

    Science.gov (United States)

    Reeves, Todd D.; Pedulla, Joseph J.

    2013-01-01

    Online professional development (OPD) for teachers is an increasingly popular and viable alternative to face-to-face professional development. While OPD can be effective, little is known about OPD's design and implementation features that maximize its impact. Using data from a large-scale OPD initiative, this correlational study (N = 1231)…

  2. POWERDRESS and diversified expression of the MIR172 gene family bolster the floral stem cell network.

    Directory of Open Access Journals (Sweden)

    Rae Eden Yumul

    Full Text Available Termination of the stem cells in the floral meristem (also known as floral determinacy is critical for the reproductive success of plants, and the molecular activities regulating floral determinacy are precisely orchestrated during the course of floral development. In Arabidopsis thaliana, regulators of floral determinacy include several transcription factor genes, such as APETALA2 (AP2, AGAMOUS (AG, SUPERMAN (SUP, and CRABSCLAW (CRC, as well as a microRNA (miRNA, miR172, which targets AP2. How the transcription factor and miRNA genes are coordinately regulated to achieve floral determinacy is unknown. A mutation in POWERDRESS (PWR, a previously uncharacterized gene encoding a SANT-domain-containing protein, was isolated in this study as an enhancer of the weakly indeterminate ag-10 allele. PWR was found to promote the transcription of CRC, MIR172a, b, and c and/or enhance Pol II occupancy at their promoters, without affecting MIR172d or e. A mutation in mature miR172d was additionally found to enhance the determinacy defects of ag-10 in an AP2-dependent manner, providing direct evidence that miR172d is functional in repressing AP2 and thereby contributes to floral determinacy. Thus, while PWR promotes floral determinacy by enhancing the expression of three of the five MIR172 members as well as CRC, MIR172d, whose expression is PWR-independent, also functions in floral stem cell termination. Taken together, these findings demonstrate how transcriptional diversification and functional redundancy of a miRNA family along with PWR-mediated co-regulation of miRNA and transcription factor genes contribute to the robustness of the floral determinacy network.

  3. Does more energy consumption bolster economic growth? An application of the nonlinear threshold regression model

    International Nuclear Information System (INIS)

    This paper separates data extending from 1971 to 2002 into the energy crisis period (1971-1980) and the post-energy crisis period (1981-2000) for 82 countries. The cross-sectional data (yearly averages) in these two periods are used to investigate the nonlinear relationships between energy consumption growth and economic growth when threshold variables are used. If threshold variables are higher than certain optimal threshold levels, there is either no significant relationship or else a significant negative relationship between energy consumption and economic growth. However, when these threshold variables are lower than certain optimal levels, there is a significant positive relationship between the two. In 48 out of the 82 countries studied, none of the four threshold variables is found to be higher than the optimal levels. It is inferred that these 48 countries should adopt a more aggressive energy policy. As for the other 34 countries, at least one threshold variable is higher than the optimal threshold level and thus these countries should adopt energy policies with varying degrees of conservation based on the number of threshold variables that are higher than the optimal threshold levels

  4. 3D map of Universe bolsters case for dark energy and dark matter

    CERN Multimedia

    2003-01-01

    "Astronomers from the Sloan Digital Sky Survey (SDSS) have made the most precise measurement to date of the cosmic clustering of galaxies and dark matter, refining our understanding of the structure and evolution of the Universe" (1 page).

  5. Bolstering Resilience through Teacher-Student Interaction: Lessons for School Psychologists

    Science.gov (United States)

    Liebenberg, Linda; Theron, Linda; Sanders, Jackie; Munford, Robyn; van Rensburg, Angelique; Rothmann, Sebastian; Ungar, Michael

    2016-01-01

    Schools are often the only formal service provider for young people living in socio-economically marginalized communities, uniquely positioning school staff to support positive psychosocial outcomes of youth living in adverse contexts. Using data from 2,387 school-going young people [Canada (N = 1,068), New Zealand (N = 591), and South Africa (N =…

  6. Bolstering resilience in the coconut kingdom: Improving adaptive capacity to climate change in Vanuatu

    International Nuclear Information System (INIS)

    This communication discusses climate change adaptation efforts underway in Vanuatu. In particular, it uncovers why community-based approaches to adaptation are more likely to bear fruit than ones driven from the top-down at the national level. The authors make this claim based on early evidence that small-scale projects (a) support community ownership over adaptation, (b) provide ongoing technical learning lessons (c) relieve pressure from capacity constraints at national administrative bodies, and (d) expedite implementation by avoiding cumbersome multilateral procedures. The first section discusses its research methods and presents important characteristics of the Vanuatu economy, people and geography. The communication then moves on to discuss Vanuatu’s vulnerability to the effects of climate change. It specifically investigates on-going efforts to adapt to natural climatic hazards in Vanuatu. Early evidence and analysis reveals lessons salient for energy and climate policy. - Highlights: ► The island state of Vanuatu is especially vulnerable to natural climatic hazards and climate change. ► Community-based approaches to climate change adaptation have unique benefits in Vanuatu. ► This note provides lessons salient for energy and climate policy in Vanuatu.

  7. Bolstering the pipeline for primary care: a proposal from stakeholders in medical education

    OpenAIRE

    Shi, Hanyuan; Kevin C. Lee

    2016-01-01

    The Association of American Medical Colleges reports an impending shortage of over 90,000 primary care physicians by the year 2025. An aging and increasingly insured population demands a larger provider workforce. Unfortunately, the supply of US-trained medical students entering primary care residencies is also dwindling, and without a redesign in this country’s undergraduate and graduate medical education structure, there will be significant problems in the coming decades. As an institution ...

  8. Bolstering the pipeline for primary care: a proposal from stakeholders in medical education

    OpenAIRE

    Hanyuan Shi; Kevin C. Lee

    2016-01-01

    The Association of American Medical Colleges reports an impending shortage of over 90,000 primary care physicians by the year 2025. An aging and increasingly insured population demands a larger provider workforce. Unfortunately, the supply of US-trained medical students entering primary care residencies is also dwindling, and without a redesign in this country's undergraduate and graduate medical education structure, there will be significant problems in the coming decades. As an institution ...

  9. Can developmental disorders be used to bolster claims from evolutionary psychology? a neuroconstructivist approach

    OpenAIRE

    Karmiloff-Smith, Annette; Thomas, Michael S.C.

    2004-01-01

    Book synopsis: Based on the Annual Symposium of the Jean Piaget Society, Biology and Knowledge Revisited focuses on the classic issue of the relationship between nature and nurture in cognitive and linguistic development, and their neurological substrates.

  10. When science replaces religion: Science as a secular authority bolsters moral sensitivity

    OpenAIRE

    Onurcan Yilmaz; Hasan G Bahçekapili

    2015-01-01

    Scientific and religious thinking compete with each other on several levels. For example, activating one generally weakens the other. Since priming religion is known to increase moral behaviour and moral sensitivity, priming science might be expected to have the opposite effect. However, it was recently demonstrated that, on the contrary, science priming increases moral sensitivity as well. The present set of studies sought to replicate this effect and test two explanations for it. Study 1 us...

  11. Using the Think-Aloud Strategy to Bolster Reading Comprehension of Science Concepts

    Science.gov (United States)

    Ortlieb, Evan; Norris, Megan

    2012-01-01

    Comprehension of text is developmental in that it begins with a child's ability to listen and make sense of language. Though listening comprehension is often the predecessor towards reading comprehension; some children maintain difficulties in listening comprehension throughout schooling and into adulthood. This quasi-experimental study…

  12. Bolstering the Scientist Component in the Training of Scientist-Practitioners: One Program's Curriculum Modifications.

    Science.gov (United States)

    Larson, Lisa M.; Besett-Alesch, Tricia M.

    2000-01-01

    Presents three specific curriculum recommendations that have been implemented at one counseling psychology program to increase the didactic and experiential scientific core. Recommendations include requiring an ongoing research practicum, a qualitative methodology course, and an advanced integrative research design course specific to the…

  13. Does Finance Bolster Superstar Companies? Banks, Venture Capital, and Firm Size in Local U.S. Markets

    OpenAIRE

    Popov, Alexander

    2009-01-01

    We study the relative effect of venture capital and bank finance on large manufacturing firms in local U.S. markets. Theory predicts that with venture capital, the firm size distribution should become more stretched-out to the right, but it’s ambiguous on the effect of banks on large firms. The empirical evidence suggests that while the average size of firms in the top bin of the firm size distribution has remained unaffected by banking sector developments, it has increased with venture capit...

  14. Tunable ultraviolet and blue light generation from Nd:YAB random laser bolstered by second-order nonlinear processes

    Science.gov (United States)

    Moura, André L.; Carreño, Sandra J. M.; Pincheira, Pablo I. R.; Fabris, Zanine V.; Maia, Lauro J. Q.; Gomes, Anderson S. L.; de Araújo, Cid B.

    2016-06-01

    Ultraviolet and blue light were obtained by nonlinear frequency conversion in a random laser (RL) based on Nd0.10Y0.90Al3(BO3)4 nanocrystalline powder. RL operation at 1062 nm, due to the 4F3/2 → 4I11/2 transition of neodymium ions (Nd3+), was achieved by exciting the Nd3+ with a tunable beam from 680 to 920 nm covering the ground state absorption transitions to the 4F9/2, (4F7/2,4S3/2), (4F5/2,2H9/2), and 4F3/2 states. Light from 340 to 460 nm was obtained via the second-harmonic generation of the excitation beam while tunable blue light, from 417 to 486 nm, was generated by self-sum-frequency mixing between the excitation beam and the RL emission.

  15. Bolstering Components of the Immune Response Compromised by Prior Exposure to Adenovirus: Guided Formulation Development for a Nasal Ebola Vaccine.

    Science.gov (United States)

    Choi, Jin Huk; Schafer, Stephen C; Freiberg, Alexander N; Croyle, Maria A

    2015-08-01

    The severity and longevity of the current Ebola outbreak highlight the need for a fast-acting yet long-lasting vaccine for at-risk populations (medical personnel and rural villagers) where repeated prime-boost regimens are not feasible. While recombinant adenovirus (rAd)-based vaccines have conferred full protection against multiple strains of Ebola after a single immunization, their efficacy is impaired by pre-existing immunity (PEI) to adenovirus. To address this important issue, a panel of formulations was evaluated by an in vitro assay for their ability to protect rAd from neutralization. An amphiphilic polymer (F16, FW ∼39,000) significantly improved transgene expression in the presence of anti-Ad neutralizing antibodies (NAB) at concentrations of 5 times the 50% neutralizing dose (ND50). In vivo performance of rAd in F16 was compared with unformulated virus, virus modified with poly(ethylene) glycol (PEG), and virus incorporated into poly(lactic-co-glycolic) acid (PLGA) polymeric beads. Histochemical analysis of lung tissue revealed that F16 promoted strong levels of transgene expression in naive mice and those that were exposed to adenovirus in the nasal cavity 28 days prior to immunization. Multiparameter flow cytometry revealed that F16 induced significantly more polyfunctional antigen-specific CD8+ T cells simultaneously producing IFN-γ, IL-2, and TNF-α than other test formulations. These effects were not compromised by PEI. Data from formulations that provided partial protection from challenge consistently identified specific immunological requirements necessary for protection. This approach may be useful for development of formulations for other vaccine platforms that also employ ubiquitous pathogens as carriers like the influenza virus. PMID:25549696

  16. Assortative and dissortative priorities for game interaction and strategy adaptation significantly bolster network reciprocity in the prisoner’s dilemma

    International Nuclear Information System (INIS)

    In 2 × 2 prisoner’s dilemma games, network reciprocity is one mechanism for adding social viscosity, which leads to cooperative equilibrium. Here we show that combining the process for selecting a gaming partner with the process for selecting an adaptation partner significantly enhances cooperation, even though such selection processes require additional costs to collect further information concerning which neighbor should be chosen. Based on elaborate investigations of the dynamics generated by our model, we find that high levels of cooperation result from two kinds of behavior: cooperators tend to interact with cooperators to prevent being exploited by defectors and defectors tend to choose cooperators to exploit despite the possibility that some defectors convert to cooperators. (paper)

  17. A finite element lower extremity and pelvis model for predicting bone injuries due to knee bolster loading

    NARCIS (Netherlands)

    Rooij, L. van; Hoof, J. van; Barbir, A.; Made, R. van der; Slaats, P.M.A.; McCann, M.J.; Ridella, S.A.; Rupp, J.D.

    2004-01-01

    Injuries to the knee-thigh-hip (KTH) complex in frontal motor vehicle crashes are of substantial concern because of their frequency and potential to result in long-term disability. Current frontal impact Anthropometric Test Dummies (ATDs) have been shown to respond differently than human cadavers un

  18. WWW.com: A Brief Intervention to Bolster a 5th Grader's Regrouping Skills in Math

    Science.gov (United States)

    Waugh, Matthew; Harrison, Gina L.

    2014-01-01

    This study examined the efficacy of a brief math intervention using cognitive behaviour instruction (CBI) supplemented by a mnemonic cue system for a 5th grade student with math computation and fluency difficulties. Regrouping operations in addition and subtraction were the targeted skills. Curriculum-based measurements were conducted at the end…

  19. Increasing the Chances of Implementing NGSS by Bolstering High School Teacher Knowledge and Views about Climate Change, a NICE NASA Example

    Science.gov (United States)

    Bleicher, R. E.

    2013-12-01

    Purpose of Presentation This paper will highlight how the results of this initial study foreshadow possibilities of NGSS (NGSS, 2013) playing out in high school classrooms in the near future. Research findings from a three-year NASA-funded project, Promoting Educational Leadership in Climate Science (PEL) will be presented. Objectives and Research Questions PEL aims to increase climate science literacy in high school teachers and students through scientific argumentation using authentic NASA data. This initial study focuses on the following questions: 1. Are teachers increasing their climate science knowledge? 2. Are there changes in teachers' views about climate change? 3. What resources and are provided to assist teachers to develop their students' scientific argumentation skills? Theoretical Framework Because of the changing nature of climate science knowledge and its relevance to societal issues, teachers must be able to understand the basic concepts and remain up-to-date on scientific issues. The need for a more thorough understanding of the concepts of climate change are highlighted by recent studies on the public perceptions and attitudes on the subject (Leiserowitz et al., 2013). Teachers need to understand the difference between skepticism as a characteristic of the nature of science and denial of climate change (Sommervillle & Hasol, 2011). Teachers need to understand the natural and human-induced factors affecting climate, and the potential consequences, and ways to mitigate and adapt to climate change. Generally, when teachers learn about a subject, they demonstrate more self-efficacy to teach about it (Bleicher & Lindgren, 2005). Analytic Strategy Data were analyzed using paired-samples t-tests, independent t -tests, and ANOVA. Latent class analysis was employed to analyze the Six America's Survey data. Correlational studies were conducted to examine possible relationships among variables. Findings in Brief Teachers' content knowledge increased significantly and teachers were more concerned about climate change after participation in PEL. Teachers with higher self-efficacy demonstrated higher climate change science knowledge. Teachers indicated that they felt more confident and were motivated to implement classroom lessons with their students that employed resources rich in NASA climate data and focused on scientific argumentation. References Bleicher, R.E., & Lindgren, J. (2005). Success in learning science and preservice science teaching self-efficacy. Journal of Science Teacher Education. 16, 205-225. Leiserowitz, A., Maibach, E., Roser-Renouf, C., Feinberg, G., & Howe, P.(2013) Climate change in the American mind: Americans' global warming beliefs and attitudes in April, 2013 Yale University and George Mason University. New Haven, CT: Yale Project on Climate Change Communication. Retrieved 7/26/13 from: http://climatechangecommunication.org/sites/default/files/reports/Climate-Beliefs-April-2013.pdf Next Generation Science Standards (NGSS). (2013). Available at http://www.nextgenscience.org/print/121. Somerville, R. C. J. & Hassol, S. J. (2011). Communicating the science of climate change. Physics Today, 64(10), 48-53.

  20. 75 FR 62718 - Disclosure for Asset-Backed Securities Required by Section 943 of the Dodd-Frank Wall Street...

    Science.gov (United States)

    2010-10-13

    ... the underlying transaction agreements for an asset securitization, sponsors or originators typically... American Securitization Forum, ASF Releases Model Representations and Warranties to Bolster Risk Retention... initiates a securitization transaction by selling or pledging to a specially created issuing entity a...

  1. Chinggis Khan: Ancestor, Buddha or Shaman? : On the uses and abuses of the portrait of Chinggis Khan

    OpenAIRE

    Charleux, Isabelle

    2009-01-01

    This article explores some past and present visual images of Chinggis Khan in order to better understand how religious and lay authorities manipulated and distorted his image to make it serve ritual purposes that bolstered their power.

  2. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... abrupt onset or long-standing symptoms. It can help diagnose conditions such as: brain tumors stroke infections ... table. Straps and bolsters may be used to help you stay still and maintain the correct position ...

  3. 77 FR 1127 - Open Meeting of the President's Council on Jobs and Competitiveness (PCJC)

    Science.gov (United States)

    2012-01-09

    .... Eastern Time. You can make an appointment to inspect statements by telephoning (202) 622-0990. All... job growth and bolster America's competitiveness around the world. The President will continue...

  4. Working with numbers and statistics a handbook for journalists

    CERN Document Server

    Livingston, Charles

    2005-01-01

    Working With Numbers and Statistics: A Handbook for Journalists will bolster math skills and improve math confidence for journalists at all skill levels. Authors Charles Livingston and Paul Voakes developed this resource book to improve journalist

  5. The great escape: the role of self-esteem and self-related cognition in terror management

    OpenAIRE

    Wisman, Arnaud; Heflick, Nathan A; Goldenberg, Jamie L.

    2015-01-01

    Integrating terror management theory and objective self-awareness theory, we propose the existential escape hypothesis, which states that people with low self-esteem should be especially prone to escaping self-awareness as a distal response to thoughts of death. This is because they lack the means to bolster the self as a defense, and the propensity to bolster the self reduces the motivation to escape from self-awareness. Five studies supported this hypothesis. Individuals low,...

  6. Use of negative pressure wound therapy in burn patients.

    Science.gov (United States)

    Teng, Shou-Cheng

    2016-09-01

    According to previous research, adjunctive negative pressure wound therapy (NPWT) can help manage infected wounds when applied along with appropriate debridement and antibiotic therapy as deemed clinically relevant. NPWT not only removes fluid, and reduces oedema, but also promotes perfusion around the wounds. In addition, NPWT may lead to improved graft fixation when used as a bolster, especially in patients who are less compliant or have poor graft fixation that result from using traditional methods. NPWT is a good choice to bolster skin grafts in young, active and less-compliant patients. We propose an enhanced segmental compartment-covered technique, which uses NPWT adjunctively as first-line wound treatment to help manage postoperative infection. Moreover, NPWT promotes granulation tissue formation to prepare the wound bed for subsequent skin graft and may be used as a bolster over the graft, which helps to attain skin graft viability. PMID:27547959

  7. School-Based Mutual Support Groups for Parents.

    Science.gov (United States)

    Simoni, Jane M.

    Parental involvement in schooling has been shown to bolster student performance. However, eliciting parents' participation in their children's schooling has proven to be an elusive task, particularly among parents from lower socio-economic and ethnic minority backgrounds. To encourage parent involvement in the school setting, an intervention that…

  8. "Universities, the Major Battleground in the Fight for Reason and Capitalism"

    Science.gov (United States)

    Jones, Gary H.

    2010-01-01

    At the turn of the twentieth century, the presidents of Harvard University, Columbia University, and the University of Chicago issued declarations bolstering institutional resistance to attempts by external agencies to influence a faculty member's stance on issues of the day. The American Association of University Professors (AAUP) emerged some…

  9. "Business Partnerships for American Education": Employer Involvement in the National Academy Foundation's High School Career Academies.

    Science.gov (United States)

    Hughes, Katherine L.; Karp, Melinda Mechur; Orr, Margaret Terry

    2002-01-01

    Data from 192 employers and 10 high schools participating in the National Academy Foundation's (NAF) career academies program reveal the benefits of employer participation and incentives and disincentives to their involvement. Findings demonstrate factors that bolster sustained employer involvement, including industry-specific support and NAF's…

  10. Undergraduate Research Engagement at Major US Research Universities. Research & Occasional Paper Series: CSHE.14.13

    Science.gov (United States)

    Douglass, John Aubrey; Zhao, Chun-Mei

    2013-01-01

    Bolstered by the recommendations of the 1998 Boyer Report, US federal agencies have put significant resources into promoting opportunities for undergraduates to engage in research. American universities and colleges have been creating support programs and curricular opportunities intended to create a "culture of undergraduate research."…

  11. Data Journalism Grows Up

    OpenAIRE

    Hewett, J.

    2015-01-01

    Data journalism has evolved partly out of computer-assisted reporting (CAR) in the USA – bolstered by freedom of information (FoI), open data and journalism education. Jonathan Hewett traces the development and teaching of data journalism in the UK.

  12. Competition and Poverty

    OpenAIRE

    Begazo, Tania; Nyman, Sara

    2016-01-01

    A literature review shows competition policy reforms can deliver benefits for the poorest households and improve income distribution. A lack of competition in food markets hurts the poorest households the most. Competition in input markets and between buyers helps farmers and small businesses. And more competitive markets bolster job growth over the longer term. More research is needed, ho...

  13. Biodemography of human ageing

    DEFF Research Database (Denmark)

    Vaupel, James W

    2010-01-01

    Human senescence has been delayed by a decade. This finding, documented in 1994 and bolstered since, is a fundamental discovery about the biology of human ageing, and one with profound implications for individuals, society and the economy. Remarkably, the rate of deterioration with age seems to be...

  14. School System (Re)design: Developing Educational Infrastructures to Support School Leadership and Teaching Practice

    Science.gov (United States)

    Hopkins, Megan; Woulfin, Sarah L.

    2015-01-01

    A central challenge for local education agencies (i.e., school districts in the United States) undergoing reform is to design systems that facilitate instructional improvement. At the core of these systems are educational infrastructures that bolster capacity building efforts and support teaching and leadership practices. Our goal for this special…

  15. Identifying Best Practices in Training Transfer: A Qualitative Study of Training Professionals

    Science.gov (United States)

    Burke, Lisa A.; Hutchins, Holly

    2008-01-01

    Qualitative data were gathered from trainers regarding best practices for supporting training transfer. Using content analysis, findings suggest interventions for bolstering transfer are best carried out in the work context and design/delivery phase, take place after training or during, and involve trainers and supervisors. However, trainers…

  16. China and Africa

    OpenAIRE

    Pigato, Miria; Tang, Wenxia

    2015-01-01

    Economic growth in Sub-Saharan Africa (SSA) has averaged roughly 5 percent per year over the past decade, improving living standards and bolstering human development indicators across the continent. Stronger public institutions, a supportive, private sector focused policy environment, responsible macroeconomic management, and a sustained commitment to structural reforms have greatly expand...

  17. Smartphone and mobile phone security for the clinician.

    Science.gov (United States)

    Barber, Harry

    2016-08-01

    Smartphones are near ubiquitous and widely used by doctors in discussing patients. In all communication doctors should take steps to protect confidentiality, yet there is a paucity of available information on how clinicians can bolster cyber security and minimize risk when using their mobile phone. PMID:27487057

  18. Mood-Congruent Memory and Natural Mood: New Evidence.

    Science.gov (United States)

    Mayer, John D.; And Others

    1995-01-01

    Presents new evidence that everyday mood does bring about a hypothesized effect on memory, termed mood-congruent memory (MCM). Results of three studies provided evidence for MCM among normal individuals (n=614). Findings support prior studies and bolster notions that mood and memory constantly covary in everyday experience. (RJM)

  19. Effective Inclusive Schools: Designing Successful Schoolwide Programs

    Science.gov (United States)

    Hehir, Thomas; Katzman, Lauren I.

    2012-01-01

    This book presents lessons learned from in-depth case studies of some of our most effective inclusive public schools. The authors conclusively demonstrate that schools can educate students with mild and severe disabilities in general education classrooms by providing special education services that link to and bolster general education…

  20. After Years of Scrutiny, Hundreds of Teams Still Fail to Make the NCAA's Grade

    Science.gov (United States)

    Sander, Libby

    2009-01-01

    Despite years of prodding from officials at the National Collegiate Athletic Association (NCAA) to bolster athletes' performance in the classroom, nearly 10 percent of all athletics teams in the NCAA's top division failed to meet the association's annual benchmark for academic progress, new data show. Of the 6,300 or so teams in Division I, the…

  1. Professional Learning Communities: A Promising Practice for Integrating Novice Special Education Teachers into the School Culture. Induction Insights. Supporting Special Education Teachers-Administrators [AII-09

    Science.gov (United States)

    National Center to Inform Policy and Practice in Special Education Professional Development, 2010

    2010-01-01

    Positive climates that encourage professional growth and teacher collaboration can bolster the impact of induction programs and may influence novice special education teachers' decisions to remain in teaching. As you plan induction programs, consider how Professional Learning Communities--the topic of this Brief--may be used to integrate special…

  2. Biomedical Research and the Animal Rights Movement: A Contrast in Values.

    Science.gov (United States)

    Morrison, Adrian R.

    1993-01-01

    This article explains how animals are used in research in an effort to counteract animal rights literature. Reveals how medical professionals and others trained in scholarship have misquoted the scientific literature to bolster their claims against the utility of animal research. (PR)

  3. IT and the Year of the Chinese Campus

    Science.gov (United States)

    Schaffhauser, Dian

    2010-01-01

    The lure of entering the China "market" has led numerous North American colleges and universities to open campuses or offices on Chinese soil--in anticipation of bolstering enrollment numbers, wooing a promising supply of Chinese students, and offering their American or other international students the opportunity to live and study abroad. In…

  4. Where's the Vision? The Concept of Utopia in Contemporary Educational Theory

    Science.gov (United States)

    Webb, Darren

    2009-01-01

    This paper explores the way in which the concept of utopia is employed within contemporary educational theory. Confronted with the relentless marketisation and managerialisation of education, there is a growing willingness to embrace utopianism as a means of bolstering hope, opening up new possibilities and catalysing change. At the same time,…

  5. Looking Past the Spin: Teach for America

    Science.gov (United States)

    Miner, Barbara

    2010-01-01

    Teach for America (TFA) is perceived as a major player in the education wars over the future of public schools, and a key ally of those who disparage teacher unions and schools of education, and who are enamored of entrepreneurial reforms that bolster the privatization of a once-sacred public responsibility. But what exactly is TFA's role in these…

  6. "Spice Girls,""Nice Girls,""Girlies," and "Tomboys": Gender Discourses, Girls' Cultures and Femininities in the Primary Classroom.

    Science.gov (United States)

    Reay, Diane

    2001-01-01

    Suggests that contemporary gendered power relations are complex, highlighting female British elementary students who assumed varied positions in relation to traditional femininities, though they all occasionally bolstered boys' power at the expense of their own. Students viewed girls as harder working, more mature, and more socially skilled, yet…

  7. Partnership for the Advancement of Information Literacy in a Nursing Program

    Science.gov (United States)

    Beck, Sheila; Blake-Campbell, Barbara; McKay, Devin

    2012-01-01

    Nursing educators know that healthcare stakeholders expect nursing graduates to be able to manage information. Consequently, many nursing education programs are exploring ways of integrating information literacy across the curriculum not only to bolster evidence-based practice, but also to enhance professional development and encourage lifelong…

  8. Parents' Interactions with Preschoolers during Shared Book Reading: Three Strategies for Promoting Quality Interactions

    Science.gov (United States)

    Han, Jisu; Neuharth-Pritchett, Stacey

    2014-01-01

    Research shows that home environments play a critical role in developing children's early literacy skills. Given the importance of developing early literacy skills to bolster children's chances for subsequent academic success, this article highlights the role of parent-child shared book reading. Summarizing research on different types of…

  9. Demanding More: Legal Standards and Best Practices for English Language Learners

    Science.gov (United States)

    Haas, Eric; Gort, Mileidis

    2009-01-01

    In the current english-only programs in California, Arizona, and Massachusetts only a small percentage of students are learning English and subject matter content. This violates the success in practice prong of "Castaneda v. Pickard" (1981). Further, these program failures bolster the claim that these programs also violate castaneda's…

  10. Vitality and Ethnolinguistic Attitudes of Acadians, Franco-Ontarians and Francophone Quebecers: Two or Three Solitudes in Canada's Bilingual Belt?

    Science.gov (United States)

    Sioufi, Rana; Bourhis, Richard Y.; Allard, Réal

    2016-01-01

    Do French-Canadian (FC) minorities in New Brunswick and Ontario remain as committed as majority Francophone Quebecers in developing their vitality within Canada's bilingual belt? FCs constitute host communities for interprovincial migrants of FC and English-Canadian (EC) background who can bolster or weaken the vitality of FCs. How FCs and ECs…

  11. Developing learning motivation in first5graders: The effect of different teaching styles

    OpenAIRE

    Gani, V; S Gani

    2009-01-01

    The article analyzes the specific features of the development of learning motivation in elementary school students at the end of their first year. The authors investigate the effects of three teaching styles: authoritarian, democratic, and unstable. The results of the study suggest that the most efficient style for bolstering learning motivation is the democratic style, while the unstable style is the least efficient.

  12. Is Prescott right? Welfare state policies and the incentives to work, learn, and retire

    NARCIS (Netherlands)

    B. Jacobs (Bas)

    2009-01-01

    textabstractThis paper bolsters Prescott's (Fed. Reserve Bank Minneap. Q. Rev. 28(1):2-13, 2004) claim that high taxes are responsible for lackluster labor market performance in Continental European countries. We develop a life-cycle model with endogenous skill formation, endogenous labor supply, an

  13. Euro-Philiacs, Euro-Sceptics and Europhobics: Higher Education Policy, Values and Institutional Research

    Science.gov (United States)

    Neave, Guy

    2005-01-01

    The European higher education landscape is inhabited by three clans: the Euro-philiac, his wicked twin, the Euro-phobic and most interesting of all, the Euro-sceptic. This unholy trinity has long been with us. Though the recent Euro electoral fiasco has in all probability served to bolster the ranks of the second and third tribes.

  14. Euro-Philiacs, Euro-Sceptics and Europhobics: Higher Education Policy, Values and Institutional Research

    NARCIS (Netherlands)

    Neave, Guy

    2005-01-01

    The European higher education landscape is inhabited by three clans: the Euro-philiac, his wicked twin, the Euro-phobic and most interesting of all, the Euro-sceptic. This unholy trinity has long been with us. Though the recent Euro electoral fiasco has in all probability served to bolster the ranks

  15. Capitalizing on Concern: The Making of Troubled Children and Troubling Youth in Late Capitalism. Introduction.

    Science.gov (United States)

    Finn, Janet L.; Nybell, Lynn

    2001-01-01

    Introduces special issue examining how constructions of pathology during childhood and adolescence play out along lines of gender, race, class, age, and citizenship in ways that locate problems in the individual, bolster extant constructions of difference and inequality, and make possible connections between constructions of pathology and…

  16. The Tonya Harding Controversy: An Analysis of Image Restoration Strategies.

    Science.gov (United States)

    Benoit, William L.; Hanczor, Robert S.

    1994-01-01

    Analyzes Tonya Harding's defense of her image in "Eye to Eye with Connie Chung," applying the theory of image restoration discourse. Finds that the principal strategies employed in her behalf were bolstering, denial, and attacking her accuser, but that these strategies were not developed very effectively in this instance. (SR)

  17. 77 FR 38093 - Meeting of National Council on the Humanities

    Science.gov (United States)

    2012-06-26

    .... Jeffrey Bolster, Associate Professor at the University of New Hampshire, and Gregory White, Qualified... INFORMATION CONTACT: Lisette Voyatzis, Committee Management Officer, 1100 Pennsylvania Ave. NW., Room 529..., 1993. Dated: June 21, 2012. Lisette Voyatzis, Committee Management Officer. BILLING CODE 7536-01-P...

  18. How Wide Is a Squid Eye? Integrating Mathematics into Public Library Programs for the Elementary Grades

    Science.gov (United States)

    Kliman, Marlene; Jaumot-Pascual, Nuria; Martin, Valerie

    2013-01-01

    Although public library programs for the elementary grades offer explorations in a wide range of topics in which mathematics plays a role, are all too rare: Mathematics offerings are typically limited to homework help. Participating in out-of-school activities that embed mathematics in authentic ways bolsters children's skill development,…

  19. Reaching Patients Across the Web.

    Science.gov (United States)

    Berlin, Joey

    2015-12-01

    The explosion of social media and the expectations of frequently refreshed content have changed the rules for physicians and practices looking to market themselves and bolster their online reputation. Just as static websites have become a relatively archaic part of the online equation, the marketing expectations for physician and practice websites have changed substantially. PMID:26630237

  20. A Blended Model: Simultaneously Teaching a Quantitative Course Traditionally, Online, and Remotely

    Science.gov (United States)

    Lightner, Constance A.; Lightner-Laws, Carin A.

    2016-01-01

    As universities seek to bolster enrollment through distance education, faculty are tasked with maintaining comparable teaching/learning standards in traditional, blended, and online courses. Research has shown that there is an achievement gap between students taking courses exclusively offered online versus those enrolled in face-to-face classes.…

  1. Unpacking Biases: Developing Cultural Humility in Early Childhood and Elementary Teacher Candidates

    Science.gov (United States)

    Brown, Elizabeth Levine; Vesely, Colleen K.; Dallman, Laura

    2016-01-01

    Changing demographics in the U.S. require a focus on educating future teachers on how to engage children and families with diverse backgrounds. Teacher educators have been charged to address teachers' cultural competence and provide pedagogical instruction for working with diverse populations. We bolster this line of inquiry by sharing activities…

  2. Moving On

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Ningxia bolsters its economic strength by tapping into Arab markets and green industries For centuries,northwest China’s Ningxia Hui Autonomous Region was a prominent fulcrum on the Silk Road,an ancient trade route linking China and the Western world via the Middle East.

  3. Enjoying the Roller Coaster Ride: Directors' Perspectives on Fostering Staff Morale in University Counseling Centers

    Science.gov (United States)

    Eells, Gregory T.; Seals, Tom; Rockett, Jeri; Hayes, Denise

    2005-01-01

    The demand for mental health services in higher education settings continues to increase and places more pressure on staff, highlighting further the importance of good staff morale in these agencies. This task of bolstering staff morale is often placed primarily on the shoulders of counseling center directors. The present article outlines several…

  4. A Delve into the Deployment of eCommerce and Higher Educational Learning

    Science.gov (United States)

    Djoleto, Wilhelmina

    2012-01-01

    Higher Educational Institutions (HEIs) and organisations have made significant investments in eCommerce/eBusiness in efforts to keep up with heightened technology penetration in organisational and institutional fabrics. These efforts have been incorporated in their strategic mission partly, to bolster their reputation. HEIs reputation depends much…

  5. House Plan May Aid Direct Lending

    Science.gov (United States)

    Field, Kelly

    2007-01-01

    Buried in a spending measure passed by the U.S. House of Representatives is a provision that could thwart Republican efforts to scuttle legislation designed to bolster the federal direct-loan program. The provision, which appears on the final page of the House's spending blueprint for the 2008 fiscal year, simply instructs the House education…

  6. Apples and Oranges Mean a New Fruit Crop: New Business Plan Competition Model Integrates Economic and Community Development

    Science.gov (United States)

    Feldman, Jacqueline; Oden, Lisa Derby

    2007-01-01

    Mount Wachusett Community College Entrepreneurial Resource Center Business Plan Competition brings together stakeholders across all economic sectors to bolster the regional economy. It also highlights entrepreneurs as a viable career choice. The competition disintegrates existing silos, provides education to all entrants, and gives business…

  7. Does Early Adolescent Sex Cause Depressive Symptoms?

    Science.gov (United States)

    Sabia, Joseph J.

    2006-01-01

    A recent study by the Heritage Foundation (Rector, Johnson, & Noyes, 2003) found evidence of a positive relationship between early sexual intercourse and depressive symptoms. This finding has been used to bolster support for funding abstinence only sex education. However, promoting abstinence will only yield mental health benefits if there is a…

  8. Technology's Role in Security.

    Science.gov (United States)

    Day, C. William

    1999-01-01

    Examines the use of technology to bolster the school security system, tips on selecting a security consultant, and several basic strategies to make buildings and grounds safer. Technological ideas discussed include the use of telephones in classrooms to expedite care in emergency situations, surveillance cameras to reduce crime, and metal…

  9. 7 CFR 3575.1 - General.

    Science.gov (United States)

    2010-01-01

    ... purpose of the Community Programs guaranteed loan program is to improve, develop, or finance essential community facilities in rural areas. This purpose is achieved through bolstering the existing private credit... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF...

  10. The UK’s Territorial and Governance Challenge: Regions, Nations and Cities

    OpenAIRE

    SHAW, Jo

    2015-01-01

    Faced with recent events at home and abroad, the UK’s political system needs to adapt to ensure prosperity and to bolster democratic legitimacy, writes Jo Shaw. She argues that devolution to cities might be a viable option to achieve these objectives, while also maintaining a balance in the UK’s complicated territorial politics.

  11. Cross-National Impacts of Public-Private Partnerships on Equitable Student Achievement: A Quasi-Experimental Assessment Using PISA 2009

    Science.gov (United States)

    Baum, Donald Rey

    2013-01-01

    Public-private partnerships are being increasingly supported and advocated for, ideologically and financially, as an approach to educational reform in many countries across the world. Proponents suggest that non-state involvement in the education sector has the potential to bolster international Education for All efforts, improve school…

  12. Rhetoric and Gender in Jane Austen's "Persuasion."

    Science.gov (United States)

    Walzer, Arthur E.

    1995-01-01

    Argues for a reading of Jane Austen's "Persuasion" that undermines Joseph Duffy's reading of the novel as a commentary on shifting social class structures, and which bolsters Nancy Armstrong's reading as a commentary on female voice and the values of the domestic household. Interprets the novel in the light of 18th-century rhetorical theory. (TB)

  13. 78 FR 66613 - National Diabetes Month, 2013

    Science.gov (United States)

    2013-11-05

    ... treatment. Diabetes can lead to serious complications, including heart disease, stroke, kidney failure, and..., advancing work toward improved treatment and care, and bolstering prevention efforts. Thanks to the Affordable Care Act, beginning in 2014, no American with diabetes can be denied health insurance based...

  14. Malaysia Workforce Development : SABER Country Report 2013

    OpenAIRE

    World Bank

    2013-01-01

    Malaysia s technical and vocational training (TVET) program is born out of a combination of ambition and necessity. The country has recorded impressive economic growth over several decades, bolstering ambitions that it should make the transition from middle- to high-income by transforming to a knowledge (K) economy. Vision 2020, announced by then Prime Minister Mahathir Mohamad, was to giv...

  15. Case Study: Fuel Cells Provide Combined Heat and Power at Verizon's Garden City Central Office

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-12-01

    This case study describes how Verizon's Central Office in Garden City, NY, installed a 1.4-MW phosphoric acid fuel cell system as an alternative solution to bolster electric reliability, optimize the company's energy use, and reduce costs in an environmentally responsible manner.

  16. Soda and Tobacco Industry Corporate Social Responsibility Campaigns: How Do They Compare?

    OpenAIRE

    Lori Dorfman; Andrew Cheyne; Friedman, Lissy C; Asiya Wadud; Mark Gottlieb

    2012-01-01

    In an article that forms part of the PLoS Medicine series on Big Food, Andrew Cheyne and colleagues compare soda companies' corporate social responsibility (CSR) campaigns - which are designed to bolster the image and popularity of their products and to prevent regulation - with the tobacco industry's CSR campaigning.

  17. Energy Perspective: Is Hydroelectricity Green?

    Science.gov (United States)

    Childress, Vincent W.

    2009-01-01

    The current worldwide concern over energy is primarily related to imported oil, oil drilling and refining capacity, and transportation capacity. However, this concern has bolstered interest in a broader range of "green" energy technologies. In this article, the author discusses the use of hydroelectricity as an alternative energy source and…

  18. An Inevitable Moment: US Brain Drain

    Science.gov (United States)

    Coppola, Brian P.

    2015-01-01

    In this article, Brian Coppola begins by discussing the 2007 National Academies of Sciences (NAS) publication, "Rising Above the Gathering Storm" which called for for reprioritizing investments because "the world is changing rapidly, and our advantages are no longer unique. Without a renewed effort to bolster the foundations of our…

  19. Practice Stories in Natural Resource Management Continuing Professional Education: Springboards for Learning

    Science.gov (United States)

    Stummann, Cathy Brown

    2014-01-01

    The use of stories from professional experience in continuing professional education has been on the rise in many fields, often aimed at bolstering capacity through sharing professional knowledge and/or supporting reflective practice. Practice stories are also suggested to be beneficial in supporting professional learning of new concepts. These…

  20. Using the World Wide Web To Teach Francophone Culture.

    Science.gov (United States)

    Beyer, Deborah Berg; Van Ells, Paula Hartwig

    2002-01-01

    Examined use of the World Wide Web to teach Francophone culture. Suggests that bolstering reading comprehension in the foreign language and increased proficiency in navigating the Web are potential secondary benefits gained from the cultural Web-based activities proposed in the study.(Author/VWL)

  1. 76 FR 80817 - Funding and Fiscal Affairs, Loan Policies and Operations, and Funding Operations; Liquidity and...

    Science.gov (United States)

    2011-12-27

    ...The Farm Credit Administration (FCA, we or us) proposes to amend its liquidity regulation. The purpose of the proposed rule is to strengthen liquidity risk management at Farm Credit System (FCS or System) banks, improve the quality of assets in the liquidity reserve, and bolster the ability of System banks to fund their obligations and continue their operations during times of economic,......

  2. Gaming the System: Culture, Process, and Perspectives Supporting a Game and App Design Curriculum

    Science.gov (United States)

    Herro, Danielle

    2015-01-01

    Games and digital media experiences permeate the lives of youth. Researchers have argued the participatory attributes and cognitive benefits of gaming and media production for more than a decade, relying on socio-cultural theory to bolster their claims. Only recently have large-scale efforts ensued towards moving game play and design into formal…

  3. Cosmic Ray Accelerators in the Large Magellanic Cloud

    OpenAIRE

    Butt, Yousaf M.

    2010-01-01

    I point out a correlation between gamma-ray emissivity and the historical star formation rate in the Large Magellanic Cloud ~12.5 Myr ago. This correlation bolsters the view that CRs in the LMC are accelerated by conglomerations of supernova remnants: i.e. superbubbles and supergiant shells.

  4. Ecocultural Patterns of Family Engagement among Low-Income Latino Families of Preschool Children

    Science.gov (United States)

    McWayne, Christine M.; Melzi, Gigliana; Limlingan, Maria Cristina; Schick, Adina

    2016-01-01

    For the 5 million low-income Latino children in the United States who are disproportionately impacted by the numerous risk factors associated with poverty, it is essential to identify proximal protective factors that mitigate these risks and bolster the academic and social skills that are foundational to a successful transition into formal…

  5. The Problem of First-Year Seminars: Risking Disengagement through Marketplace Ideals

    Science.gov (United States)

    Hickinbottom-Brawn, Sarah; Burns, David P.

    2015-01-01

    First-year seminars (FYS) have become increasingly prevalent in North American postsecondary institutions. The popularity of such initiatives owes much to the belief that providing unprepared students general life and academic skills can bolster engagement and thereby improve retention. In this paper we argue that, despite their good intentions,…

  6. LEADERSHIP EFFECTIVENESS IN CROSS-CULTURAL BUSINESS ENVIRONMENT

    OpenAIRE

    GOSTROUSHKO VLADLENA

    2015-01-01

    Businesses are operating in an increasingly global environment, which requires careful consideration of cultural differences when marketing goods and services worldwide. Whether you are dealing with international partners or setting up an office in an overseas location, understanding typical leadership styles in that country can be extremely beneficial to bolstering smooth-running relationships.

  7. Investigation of the influence of friction pairs geometrical parameters of wagon truck spring - frictional set on the effectiveness of their operation

    Directory of Open Access Journals (Sweden)

    Oleg CHEREPOV

    2011-01-01

    Full Text Available The article gives an account of the results of the analytical and numerical modeling of force action of friction pairs “truck bolster – frictional wedge” and “frictional wedge – frictional plank”. There have been obtained formulas for determining con-straint reactions according to friction pairs geometrical parameters which makes it possible to find their rational values.

  8. Assessing Conscientious Personality in Primary Care: An Opportunity for Prevention and Health Promotion

    Science.gov (United States)

    Israel, Salomon; Moffitt, Terrie E.

    2014-01-01

    The articles in this special section bolster the already strong evidence base that personality differences in the trait of conscientiousness predict health. What is now needed is a research agenda for translating documented risk associations between low conscientiousness and poor health into policies and interventions that improve health outcomes…

  9. Professional Learning Communities: A Practice to Support the Induction and Retention of Novice Special Education Teachers. Induction Insights. Supporting Special Education Teachers - Teacher Educators [TEII-5

    Science.gov (United States)

    National Center to Inform Policy and Practice in Special Education Professional Development, 2010

    2010-01-01

    Collaboration among novice special education teachers and their general education colleagues can bolster the impact of induction programs for all novice teachers, including special education teachers. Strong, supportive collaborative structures also can influence novice special education teacher retention. A Professional Learning Community--the…

  10. Leadership Choices in Early Care and Education

    Science.gov (United States)

    Goffin, Stacie G.; Washington, Valora

    2008-01-01

    After more than a century of evolution, early care and education is in transition. No longer is it a narrow endeavor of relative obscurity and of limited interest to leaders from outside the field. Early care and education has become of interest to K-12 leaders seeking to bolster school reform efforts; to corporate entrepreneurs and stockholders…

  11. International Students' Emotional Security and Dignity in an Australian Context: An Aspect of Psychological Well-Being

    Science.gov (United States)

    Tananuraksakul, Noparat; Hall, David

    2011-01-01

    This article explores non-native English-speaking students' emotional security and dignity responses to their English language proficiency in an Australian context. Confidence is a source of emotional security bolstering dignity. Without it, students lack emotional security, diminishing their dignity when communicating with culturally different…

  12. Anatomy of an Alumnus. Commentary

    Science.gov (United States)

    Weerts, David

    2011-01-01

    In today's resource scarce environment, it is no surprise that colleges and universities are seeking innovative ways to bolster charitable giving among their alumni. Stripling's article focuses on how alumni research conducted at Claremont McKenna College aims to find out what graduates need and expect from their alma mater. Claremont McKenna…

  13. Ideology, Materiality, and Counterpublicity: William E. Simon and the Rise of a Conservative Counterintelligentsia

    Science.gov (United States)

    Asen, Robert

    2009-01-01

    As a conceptual term, "counterpublic" serves scholarship best when contributing to a critical-theory project, which means that particular constellations of materiality and ideology may bolster some calls for counterpublicity while gainsaying others. This may be investigated by examining how a text upholds or betrays an advocate's values, seeking…

  14. SOE Execs:Get Ready For Stock Incentives

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Stock option incentive plan will soon be available to state-owned enterprise executives, but will it lead to greater prosperity or new problems? Atrailblazing new scheme to infuse state-owned enterprises (SOEs) with incentive stock options is underway. It's a plan that may bolster company performance, but it's

  15. The Role of Transnational Feminism in Psychology: Complementary Visions

    Science.gov (United States)

    Grabe, Shelly; Else-Quest, Nicole M.

    2012-01-01

    Denmark and Segovich's (2012), Hyde's (2012), and Marecek's (2012) reflections on the authors' article (Else-Quest & Grabe, 2012) further bolster the need for feminist psychology to investigate gender disparities in power. The authors offer a rejoinder that draws together the commonalities in their various perspectives by putting the study of…

  16. The Masculine Ideal: Rape on Prime-Time Television, 1976-1978.

    Science.gov (United States)

    Cuklanz, Lisa M.

    1998-01-01

    Contributes to scholarship regarding whether, when, and how feminist formulations of rape made their way into the mainstream by examining 25 episodes of prime-time television featuring rape as a primary plot element from 1976 through 1978. Finds that these episodes bolster hegemonic masculinity by focusing on male protagonists, depicting them as…

  17. 76 FR 16481 - Lifeline and Link Up Reform and Modernization; Federal-State Joint Board on Universal Service...

    Science.gov (United States)

    2011-03-23

    ...In this document, the Federal Communications Commission (Commission) puts forward a set of proposals to reform and modernize Lifeline/Link Up, including recommendations of the Federal-State Joint Board on Universal Service, Government Accountability Office, and the National Broadband Plan. The reforms proposed will significantly bolster protections against waste, fraud, and abuse; control the......

  18. African American Adolescent Engagement in the Classroom and Beyond: The Roles of Mother's Racial Socialization and Democratic-Involved Parenting

    Science.gov (United States)

    Smalls, Ciara

    2009-01-01

    Previous research has explored how differential youth outcomes are associated with racial socialization and parenting style individually, but very little work has examined whether democratic-involved parenting style bolsters the positive link between racial messages and adolescent outcomes. The purpose of this study was to examine mothers' use of…

  19. Locking in on Latin America

    Institute of Scientific and Technical Information of China (English)

    MICHAEL; RICE

    2006-01-01

    China cautious as it sets up generous investment in Latin America The United States is keeping a watchful eye as China bolsters political and economic ties with Latin America. The situation has U.S. political analysts trying to determine just how China s emerging influence

  20. The Impact of Motivational Interviewing on Client Experiences of Cognitive Behavioral Therapy for Generalized Anxiety Disorder

    Science.gov (United States)

    Kertes, Angela; Westra, Henny A.; Angus, Lynne; Marcus, Madalyn

    2011-01-01

    Motivational Interviewing (MI) has recently been applied to the treatment of anxiety disorders in an effort to bolster engagement with and response rates to cognitive behavioral therapy (CBT). In a recent randomized control trial, the addition of MI as a pretreatment compared to no pretreatment was found to significantly improve response to CBT…

  1. From Shards to Stained Glass: Crowdsourcing an E-Book

    Science.gov (United States)

    Fontichiaro, Kristin

    2012-01-01

    In this article, the author discusses crowdsourcing an e-book--gathering wide, diverse opinions from the school library community (including academics, practitioners, vendors, and others), and gathering those results in a free e-book. As e-book publishers, school librarians could be active agents, bolstering community energy, creating a forum for…

  2. Fatigue life analysis of die forged railway axle manufactured from C30 steel

    Directory of Open Access Journals (Sweden)

    Libor Trško

    2014-06-01

    Full Text Available With respect to the manufacturing process, different parts of one structural component can have different fatigue properties. In this study, the fatigue life of a railway axle manufactured from C30 steel by die forging is evaluated in the part of the axle bolster and axle body. According to the fatigue test results obtained at high frequency tension - compression fatigue tests (f ≈ 20 kHz, R = -1, T = 20 ± 5 °C, due to the higher level of work hardening of the axle bolster, the fatigue strength of material in this part is significantly higher than in the axle body. Different fatigue strength of these parts were observed despite the fact, that results of static tensile tests did not proved any important differences in the ultimate tensile strength, yield point and elongation. 

  3. Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic.

    Science.gov (United States)

    Majchrzak, Kinga; Nelson, Michelle H; Bailey, Stefanie R; Bowers, Jacob S; Yu, Xue-Zhong; Rubinstein, Mark P; Himes, Richard A; Paulos, Chrystal M

    2016-03-01

    Cancer immunotherapy is one the most effective approaches for treating patients with tumors, as it bolsters the generation and persistence of memory T cells. In preclinical work, it has been reported that adoptively transferred CD4+ and CD8+ lymphocytes that secrete IL-17A (i.e., Th17 and Tc17 cells) regress tumors to a greater extent than IFN-γ(+)Th1 or Tc1 cells in vivo. Herein, we review the mechanisms underlying how infused Th17 and Tc17 cells regress established malignancies in clinically relevant mouse models of cancer. We also discuss how unique signaling cues--such as co-stimulatory molecules (ICOS and 41BB), cytokines (IL-12 and IL-23) or pharmaceutical reagents (Akt inhibitors, etc.)--can be exploited to bolster the therapeutic potential of IL-17(+) lymphocytes with an emphasis on using this knowledge to improve next-generation clinical trials for patients with cancer. PMID:26825102

  4. The '419 Scam': An Unacceptable 'Power of the False'?

    OpenAIRE

    John Scannell

    2014-01-01

    One of the more virulent manifestations of a burgeoning virtual world is the very physical waste that underwrites its proliferation. Illegal e-waste dumping in Western Africa not only wreaks havoc on the ecosystems of its destination countries, but also bolsters the arsenal of the "419 scammers" and 'data miners,' in turn. As the pernicious nature of such online fraud is protested by Western media, and the global economic inequalities that foster such deception is conveniently ignored, the ma...

  5. Asian Equity Markets; Growth, Opportunities, and Challenges

    OpenAIRE

    Charles Frederick Kramer; Catriona Purfield; Hiroko Oura; Andreas Jobst

    2006-01-01

    Asian equity markets have grown significantly in size since the early 1990s, driven by strong international investor inflows, growing regional financial integration, capital account liberalization, and structural improvements to markets. The development of equity markets provides a more diversified set of channels for financial intermediation to support growth, thus bolstering medium-term financial stability. At the same time, as highlighted by the May-June 2006 market corrections, the increa...

  6. Using Private Contracts to Create Adoptions from Foster Care

    OpenAIRE

    Mary Eschelbach Hansen

    2007-01-01

    Creating adoptions for children waiting in foster care is a good investment, but the number of adoptions created each year meets only a fraction of the need. This paper explores how the organization of the delivery of social services to waiting children and prospective adoptive families influences adoption creation. Cross-section time-series estimates are supplemented with a new augmented fixed effects procedure to demonstrate that the use of contracts with private agencies bolsters adoption ...

  7. The Cost and Value of Early Foreign Language Instruction in America

    Institute of Scientific and Technical Information of China (English)

    张远艳

    2016-01-01

    In light of NCLB and the emphasis for the government to improve student performance, a quick, agile and competent mind, functioning with high cognitive abilities, is the aim in education. And if through Foreign Language instruction we can bolster reading abilities, the basis of all academic achievement. The aim of this essay is to analyze the cost and value of early foreign language instruction and promote, advance, and garner support and understanding about the need for early foreign language study.

  8. Returns on Business-to-Business Relationship Marketing Investments: Strategies for Leveraging Profits

    OpenAIRE

    Robert W. Palmatier; Srinath Gopalakrishna; Mark B. Houston

    2006-01-01

    Firms invest heavily in different types of business-to-business relationship marketing activities in the belief that such programs bolster their bottom line. In this study, we develop and test a conceptual model that links customer-specific relationship marketing investments to short-term, customer-specific financial outcomes. Data from a matched set of 313 business customers covered by 143 salespeople of 34 selling firms indicate that investments in social relationship marketing pay off hand...

  9. Redundancy in Public Transit - Vol. IV: Structure, Competition, and Reliability in Planning and Operations

    OpenAIRE

    Jonathan B. Bendor

    1980-01-01

    In contrast to the private sector, public services in the United States are organized monopolistically. the structure of public sector monopoly has been bolstered by the conventional wisdom in public administration, which has traditionally maintained that functional duplication is wasteful. This position has recently been challenged by a small group of political scientists and economists who suggest that a redundant organizational structure can make the execution of a given program more relia...

  10. PUBLIC-PRIVATE SECTOR RELATIONSHIPS IN DEVELOPING COUNTRIES

    OpenAIRE

    Martin J. Staab

    2003-01-01

    This paper refutes the conventional wisdom, bolstered in the wake of the Asian financial crisis that governments should not become too friendly with the private sector but, instead, should remain neutral and at arms-length distance. The empirical findings presented here indicate that countries in which governments have forged close and cooperative working relationships with the private sector have had much greater economic success. Furthermore, countries with more business-friendly public-pri...

  11. Calling the EU's bluff. Who are the real champions of biodiversity and traditional knowledge in the EU-Central American and EU-Community of Andean Nations Association Agreements?

    International Nuclear Information System (INIS)

    Global Europe and the EU's Raw Materials Initiative are designed to bolster the EU's economic position - whatever the cost - in the face of fierce global competition for both markets and resources, especially from emerging economies such as China and India. The EU also fears losing trade to the US, which has already secured trade and investment concessions from countries in the Western hemisphere, through the Dominican Republic-Central American Free Trade Agreement (DR-CAFTA) and other bilateral trade agreements.

  12. Capital Controls: Mud in the Wheels of Market Discipline

    OpenAIRE

    Kristin J. Forbes

    2004-01-01

    Widespread support for capital account liberalization in emerging markets has recently shifted to skepticism and even support for capital controls in certain circumstances. This sea-change in attitudes has been bolstered by the inconclusive macroeconomic evidence on the benefits of capital account liberalization. There are several compelling reasons why it is difficult to measure the aggregate impact of capital controls in very different countries. Instead, a new and more promising approach i...

  13. A view of the economic crisis and the Federal Reserve’s response

    OpenAIRE

    Janet L. Yellen

    2009-01-01

    The Federal Reserve has responded to a severe recession by developing programs to bolster the financial system and restore economic growth. The Fed has the tools to unwind these programs when appropriate, maintaining price stability. The following is adapted from a speech delivered by the president and CEO of the Federal Reserve Bank of San Francisco to the Commonwealth Club in San Francisco on June 30, 2009.

  14. Current ADC Linker Chemistry

    OpenAIRE

    Jain, Nareshkumar; Smith, Sean W.; Ghone, Sanjeevani; Tomczuk, Bruce

    2015-01-01

    The list of ADCs in the clinic continues to grow, bolstered by the success of first two marketed ADCs: ADCETRIS® and Kadcyla®. Currently, there are 40 ADCs in various phases of clinical development. However, only 34 of these have published their structures. Of the 34 disclosed structures, 24 of them use a linkage to the thiol of cysteines on the monoclonal antibody. The remaining 10 candidates utilize chemistry to surface lysines of the antibody. Due to the inherent heterogeneity of conjugati...

  15. Scientists taste entrepreneurial life

    Directory of Open Access Journals (Sweden)

    Paula Gould

    2005-11-01

    Full Text Available Financing retirement from university life with the proceeds of a smart invention is undeniably an attractive prospect. Unfortunately, attempts to commercialize academic research can result all too easily in knock-backs and disappointed investors, rather than a generous pension deposit. But, if you pitch the right idea to the right market, money can be made. Not only that, the technology could do a great deal of good, while also bolstering its inventor's curriculum vitae.

  16. Time-Compressed Professionalization: The Experience of Public School Sign Language Interpreters in Mountain-Plains States

    OpenAIRE

    Bolster, Laurie A

    2005-01-01

    Laurie Bolster Abstract Rapid establishment of interpreting skill and knowledge standards for public school sign language interpreters has created a virtual mandate for their immediate, time-compressed, professionalization. A series of federal laws requiring accessibility to communication for deaf people have escalated demand for interpreters far beyond the supply. Thousands of people with varying levels of knowledge, skill, and experience, have been drawn into service in ...

  17. Photovoltaic Barometer - EurObserv'ER - April 2013

    International Nuclear Information System (INIS)

    After the euphoria of 2011, the European Union's photovoltaic market slowed right down in 2012. EurObserv'ER puts newly-connected capacity in 2012 at 16.5 GWp compared to 22 GWp in 2011, which is a 25% slide. At global level the market generally held up, with just over 30 GWp installed, bolstered by the build-up of the America and Asian markets

  18. Do Smallholder, Mixed Crop-Livestock Livelihoods Encourage Sustainable Agricultural Practices? A Meta-Analysis

    OpenAIRE

    Rudel, Thomas K.; Oh-Jung Kwon; Paul, Birthe K.; Maryline Boval; Rao, Idupulapati M.; Diana Burbano; Megan McGroddy; Amy M. Lerner; Douglas White; Mario Cuchillo; Manuel Luna; Michael Peters

    2016-01-01

    As calls for bolstering ecosystem services from croplands have grown more insistent during the past two decades, the search for ways to foster these agriculture-sustaining services has become more urgent. In this context we examine by means of a meta-analysis the argument, proposed by Robert McC. Netting, that small-scale, mixed crop-livestock farming, a common livelihood among poor rural peoples, leads to environmentally sustainable agricultural practices. As predicted, mixed crop-livestock ...

  19. Coral Bleaching Susceptibility Is Decreased following Short-Term (1–3 Year) Prior Temperature Exposure and Evolutionary History

    OpenAIRE

    Haslun, Joshua A.; Strychar, Kevin B.; Gregory Buck; Sammarco, Paul W.

    2011-01-01

    Coral exposed to short periods of temperature stress (≥1.0°C above mean monthly maximum) and/or increased frequencies of high temperatures may bolster resilience to global warming associated with climate change. We compared Montastraea cavernosa (Linnaeus, 1767; Cnidaria, Scleractinia, Faviidae) from the Florida Keys National Marine Sanctuary (FKNMS) and the Flower Garden Banks National Marine Sanctuary (FGBNMS). Thermal stress has been reported frequently within the FKNMS; however, corals in...

  20. Implementation Of 5S Quality Tool In Manufacturing Company A Case Study

    OpenAIRE

    Vibhor Kakkar; Vijay Singh Dalal; Vineet Choraria; Ashish S. Pareta; Anmol Bhatia

    2015-01-01

    Abstract 5S system is a technique which maintains the quality of working conditions in the organization. Amongst various available Lean resources 5S is a powerful technique that can bolster objectives of the organization to get continuous improvement in performance and productivity. This paper presents the implementation of 5S in a manufacturing company amp 5S rating system was used to audit all changes in the company which enhanced the efficiency of the workers amp ultimately the productivit...

  1. Sustainable yoga apparel

    OpenAIRE

    Jason, Helen

    2014-01-01

    The two major purposes of this study are to establish whether there is an interest in sustainably regarding locally made yoga sports equipment and to create a design concept for a product line of yoga apparel which is genuinely eco-friendly. The product line consists of a yoga mat bag, straps, pillows and a bolster. Research into issues surrounding sustainability and yoga guided the design process. In order to meet user requirements, yoga classes were observed, a survey was conducted and ...

  2. CAES Annual Report FY 2011

    Energy Technology Data Exchange (ETDEWEB)

    Kortny Rolston

    2011-10-01

    The Center for Advanced Energy Studies was created to lead research programs important to the nation, attract students and faculty to the Idaho universities and act as a catalyst for technology-based economic development. CAES is striving to meet those goals by continuing to develop its infrastructure and equipment capabilities, expand its research portfolio and bolster Idaho's energy workforce. This Annual Report details the progress CAES made in FY 2011 toward fulfilling its research, education and economic development missions.

  3. Emergent gravity: From statistical point of view

    OpenAIRE

    Majhi, Bibhas Ranjan

    2012-01-01

    Near the event horizon of a black hole, the effective theory is two dimensional conformal theory. Here we show that the holographic modes characterising this underlying conformal symmetry and the basic definition of entropy $S$ in statistical mechanics lead the equipartition law of energy. We also show that $S$ is proportional to the gravity action which suggests the emergent nature of gravity. This is further bolstered by expressing the generalised Smarr formula as a thermodynamic relation, ...

  4. Transmission studies of intestinal schistosomiasis in Lake Albert, Uganda and experimental compatibility of local Biomphalaria spp

    DEFF Research Database (Denmark)

    Kazibwe, F.; Makanga, B.; Rubaire-Akiiki, C.;

    2010-01-01

    Despite ongoing preventive chemotherapy campaigns, intestinal schistosomiasis is hyper-endemic in shoreline communities living along Lake Albert, Uganda. To provide a deeper insight into the local epidemiology of Schistosoma mansoni, a variety of field-based studies were undertaken focusing upon ...... environmental modification(s), i.e. improvement in sanitation and hygiene and control of snail populations, is needed to bolster the impact of chemotherapy-based interventions....

  5. The chemistry and biology of zoanthamine alkaloids and Illicium sesquiterpenes

    OpenAIRE

    Trzoss, Lynnie L.

    2012-01-01

    Natural products, or secondary metabolites, have proven significant to the existence of life. They have been used for countless reasons throughout history, including nonessential purposes such as dyes for textiles and paints. Less trivial uses, such as those related to health better demonstrate the importance of natural products. Toxic natural products had been used to bolster hunting efficiency and insect pheromones. Therapeutic natural products have long been used as dietary supplements and...

  6. Synthetic studies toward complex Schisandraceae and zoanthamine natural products

    OpenAIRE

    Fischer, Derek A.

    2008-01-01

    Natural products, or secondary metabolites of plants and animals, have proven invaluable to humanity. We have used them for myriad reasons throughout history, including non- essential purposes such as dyes for textiles and paints. Less trivial uses, such as those related to food and health better demonstrate the importance of natural products. We have made use of toxic natural products to bolster hunting efficiency (e.g. poison tipped darts), and insect pheromones and natural products with an...

  7. From Corporate Philanthropy to Creating Shared Value: Big Pharma’s New Business Models in Developing Markets

    OpenAIRE

    Smith N. Craig

    2016-01-01

    Some big companies have discovered opportunities to bolster their bottom line in emerging and developing markets by creating social value at the same time as generating economic returns. In the pharma industry some have taken the lead in using this concept of shared value to innovate and grow their business, especially in developing markets. Eli Lilly launched the NCD partnership to combat diabetes in underserved areas around the globe. The partnership improves awareness of the disease an...

  8. The Teacher-Student Data Link Project: Three Lasting Accomplishments

    OpenAIRE

    Cassie Pickens Jewell; Kristin Hallgren; Sarah Wissel

    2014-01-01

    In 2010, the Bill & Melinda Gates Foundation invited five states and three pilot districts in each state to participate in the Teacher-Student Data Link (TSDL) project. Mathematica developed a report presenting findings from 2011, the project’s first year of implementation. Building on that report, this brief articulates three lasting accomplishments of the TSDL project, and presents additional resources and best practices for initiatives like TSDL that intend to bolster linked teacher-stud...

  9. Medical students’ awareness and perception of national health examinations

    OpenAIRE

    Wu, Lii-Tzu; Lai, Tsuei-Yuan; Liu, Chiu-Shong; Lee, Cheng-Chun; Lin, Cheng-Chieh; Horng, Meei-Ling

    2014-01-01

    Key ingredients for upgrading health care include bolstering and appraising professional medical education. Health examination as a crucial element of health care that we must incorporate into medical education. This research evaluates medical students’ awareness of national health examinations. Two surveys, focused on health examination knowledge and perspective, were conducted for first- to fourthyear medical students, results analyzed by descriptive statistics, t-test and ANOVA. Research s...

  10. Selective Elimination of Human Regulatory T Lymphocytes In Vitro With the Recombinant Immunotoxin LMB-2

    OpenAIRE

    Attia, Peter; Daniel J Powell; Maker, Ajay V; Kreitman, Robert J.; Pastan, Ira; Rosenberg, Steven A.

    2006-01-01

    CD4+CD25+ T-regulatory cells (Treg) can inhibit the proliferation and cytokine secretion of CD4+CD25− helper T cells in mice and humans. In murine tumor models, the presence of these Treg cells can inhibit the antitumor effectiveness of T-cell transfer and active immunization approaches. We have thus initiated efforts to eliminate Treg cells selectively from human peripheral blood mononuclear cells (PBMCs) to potentially bolster antitumor responses. LMB-2 is a recombinant immunotoxin that is ...

  11. The Irish Economy Today: Albatross or Phoenix?

    OpenAIRE

    Fitz Gerald, John

    2011-01-01

    In 2001 the policy issues facing Ireland were very different than they are today. Growth had surpassed expectations and the high level of unemployment of the 1980s and early 1990s had been eliminated. Instead of emigration, Ireland was experiencing steady immigration as Irish emigrants of the 1980s returned and as skilled foreigners came to bolster the human capital of the work force. The economy and society reflected this turnaround with the population as a whole seeing a...

  12. Book review: The power surge: energy, opportunity, and the battle for America’s future

    OpenAIRE

    Pirgova, Luba

    2013-01-01

    "The Power Surge: Energy, Opportunity and the Battle for America’s Future." Michael Levi. Oxford University Press. May 2013. --- In The Power Surge, Michael Levi takes readers inside the USA’s unfolding energy revolutions, and discusses how both fracking and eco-startups can offer big opportunities for the country to strengthen its economy, bolster its security, and protect the environment. Luba Pirgova finds that academic readers may be disappointed by the lack of scholarly references, but f...

  13. Digital Economy Impact on Society

    OpenAIRE

    Lazãr Cristina; Epure Dãnuþ Tiberius; Spãtariu Elena Cerasela

    2011-01-01

    With this study we’re trying to bolster up the idea that digitization of information combined with the Internet is a form of general purpose technology, which rose a wide range of new possible combinations that could be provided by the digital economy. The impact of the digital economy over societies can be seen and recognized even if only part of it is measurable. The effects of digitalization the economy are seen more in the new activities and products than the productivity.

  14. Can Statistics Tell Us What We Do Not Want to Hear? The Case of Complex Salary Structures

    OpenAIRE

    Gray, Mary W.

    1993-01-01

    It often appears that the most, indeed perhaps the only, effective role of statistics is to bolster decisions policymakers were prepared to take on other grounds. The secondary effects of smoking, the sex differential in SAT scores, the census undercount controvery, the validity of DNA evidence and the evidence of the relation of the race of the victim to the imposition of the death pernalty all provide examples of the intertwining of political and statistical considerations. Although the cou...

  15. Kingdom of the Netherlands; Aruba: 2007 Article IV Consultation: Staff Report; Public Information Notice on the Executive Board Discussion; and Statement by the Executive Director for the Kingdom of the Netherlands -Aruba

    OpenAIRE

    International Monetary Fund

    2008-01-01

    Aruba is one of the most developed islands in the Caribbean. Still, it is vulnerable to external shocks owing to its heavy dependence on tourism and a steady increase in public debt. Policies to support further fiscal consolidation and boost Aruba’s growth potential are needed. Maintaining macroeconomic stability will require fiscal adjustment and an appropriately tight monetary policy. Bolstering the growth potential will require creating the right conditions for private investment and div...

  16. The foreign policy of Egypt under Mubarak : the primacy of regime security

    OpenAIRE

    Shama, Nael M.

    2008-01-01

    The study explores Egypt’s foreign policy under President Hosni Mubarak. It focuses on the way Mubarak's regime dealt with internal and external threats to maintain security and bolster his internal hold on power. Two case studies are chosen to test the hypotheses: Egypt’s reluctance to reestablish diplomatic ties with the Islamic Republic of Iran and Egypt’s response to the Greater Middle East Initiative proposed by the Bush administration and the series of Western efforts aimed at promo...

  17. Strategy: The Logic of War and Peace rev. and enlarged ed. by Edward N. Luttwak Cambridge, MA: The Belknap Press of Harvard University Press, 2001 / Book Review

    OpenAIRE

    Wirtz, James J.

    2003-01-01

    In the 1980s scholars in the ªelds of history and political science rediscovered the work of Carl von Clausewitz, the Prussian philosopher of war. This renewed interest sparked a brief revival of the study of war and strategy (the latter of which encompasses efforts to exploit war’s dialectic to achieve military and political victory). After relying for decades on operations research to minimize the likelihood of nuclear war by bolstering deterrence—an approach that largely eli...

  18. Building the Knowledge-Based Economy in Countries in Transition—from Concepts to Policies

    OpenAIRE

    David A. Dyker; Slavo Radosevic

    2000-01-01

    Conventional transition policies of a predominantly macroeconomic character have done a good deal to create necessary conditions for building the knowledge-based economy in the countries of Eastern Europe and the former Soviet Union. Establishment of sufficient conditions for such an evolution will require a different approach to policy-making, which will range much more widely across the gamut of possible economic policies, but will at the same time seek to bolster state action with the acti...

  19. The Crisis of 1866

    OpenAIRE

    Marc Flandreau; Stefano Ugolini

    2014-01-01

    The collapse of Overend Gurney and the ensuing Crisis of 1866 was a turning point in British financial history. The achievement of relative stability was due to the Bank of England’s willingness to offer generous assistance to the market in a crisis, combined with an elaborate system for maintaining the quality of bills in the market. We suggest that the Bank bolstered the resilience of the money market by monitoring leverage-building by money market participants and threatening exclusion fro...

  20. weSPOT: Inquiry based learning meets learning analytics

    OpenAIRE

    Specht, Marcus; Bedek, Michael; Duval, Erik; Held, Peter; Okada, Alexandra; Stefanov, Krassen; Parodi, Elisabetta; Kikis-Papadakis, K; Strahovnik

    2013-01-01

    weSPOT, a project supported by the European Commission, addresses several challenges to building personal knowledge, specifically in the area of science. It focuses on inquiry-based learning, in which the learner takes the role of a self-motivated explorer, and provides support for building these skills. The main problem areas weSPOT tackles are the general lack of inquiry skills in students from ages 12 to 25, the dearth of technological support to bolster students’ curiosity, linking ev...

  1. Pendulum how past generations shape our present and predict our future

    CERN Document Server

    Williams, Roy H

    2012-01-01

    From New York Times bestselling author and speaker Roy H. Williams and business guru Michael R. Drew comes a revolutionary book outlining the surprising societal phenomenon that unlocks the secrets to success in the worlds of business, politics, advertising, entertainment, and more. Previously available only through private speaking engagements, the wisdom that bolstered the careers of political leaders, celebrities and business owners is now available to you in this entertaining and innovative book.

  2. China: Trotz hoher gesamtwirtschaftlicher Dynamik noch keine Lokomotive der Weltwirtschaft

    OpenAIRE

    Dreger, Christian; Zhang, Yanqun

    2012-01-01

    With China's economic integration a new growth center capable of having a decisive influence on the global economy has emerged. Thus, strong increases in production in China could help to bolster the flagging economies of the industrialized world. This article will analyze the extent to which China already determines macroeconomic growth in the euro area and the US today. It considers the example of the Chinese economic stimulus program implemented during the financial crisis. The analysis sh...

  3. Housing condition alters immunological and reproductive responses to day length in Siberian hamsters (Phodopus sungorus)

    OpenAIRE

    Weil, Zachary M.; Workman, Joanna L.; Nelson, Randy J.

    2007-01-01

    During winter, increased thermoregulatory demands coincide with limited food availability necessitating physiological trade offs among expensive physiological processes resulting in seasonal breeding among small mammals. In the laboratory, short winter-like day lengths induce regression of the reproductive tract, but also enhance many aspects of immune function. It remains unspecified the extent to which bolstered immune responses in short days represent enhanced immune function per se compar...

  4. Modelling Coral Reef Futures to Inform Management: Can Reducing Local-Scale Stressors Conserve Reefs under Climate Change?

    OpenAIRE

    Gurney, Georgina G.; Melbourne-Thomas, Jessica; Geronimo, Rollan C.; Aliño, Perry M.; Craig R. Johnson

    2013-01-01

    Climate change has emerged as a principal threat to coral reefs, and is expected to exacerbate coral reef degradation caused by more localised stressors. Management of local stressors is widely advocated to bolster coral reef resilience, but the extent to which management of local stressors might affect future trajectories of reef state remains unclear. This is in part because of limited understanding of the cumulative impact of multiple stressors. Models are ideal tools to aid understanding ...

  5. Science Alive!: Connecting with Elementary Students through Science Exploration

    OpenAIRE

    Aarti Raja; Emily Schmitt Lavin; Tamara Gali; Kaitlin Donovan

    2016-01-01

    A novel program called Science Alive! was developed by undergraduate faculty members, K–12 school teachers, and undergraduate students to enrich science, technology, engineering, and mathematics (STEM) literacy at community schools located near the university. The ultimate goal of the program is to bolster the scientific knowledge and appreciation of local area students and community members and serve as a model for similar programs. Through the program, we observed that elementary school stu...

  6. Science Alive!: Connecting with Elementary Students through Science Exploration†

    OpenAIRE

    Raja, Aarti; Lavin, Emily Schmitt; Gali, Tamara; Donovan, Kaitlin

    2016-01-01

    A novel program called Science Alive! was developed by undergraduate faculty members, K–12 school teachers, and undergraduate students to enrich science, technology, engineering, and mathematics (STEM) literacy at community schools located near the university. The ultimate goal of the program is to bolster the scientific knowledge and appreciation of local area students and community members and serve as a model for similar programs. Through the program, we observed that elementary school stu...

  7. Motivational factors that influence the acceptance of Moodle using TAM

    OpenAIRE

    Duarte Hueros, Ana María; Arteaga Sánchez, Rocío

    2010-01-01

    Moodle and other virtual teaching platforms have bolstered the ability and motivation of universities to support distance learning. The aim of our study is to improve understanding of the motivational factors behind student satisfaction, or dissatisfaction, with the Web-based learning platform, Moodle. Our study extends the Technology Acceptance Model (TAM) to include technical support and perceived self-efficacy, with the expectation that they influence usage of Moodle. We surveyed 226 stu...

  8. Republic of Belarus; 2009 Article IV Consultation and Second Review Under the Stand-By Arrangement-Staff Report Informational Annex; Staff Statement; Public Information Notice on the Executive Board Discussion; and Press Release

    OpenAIRE

    International Monetary Fund

    2009-01-01

    This 2009 Article IV Consultation highlights that Belarus has so far escaped a significant fall in output, despite a sharp fall in external demand. GDP declined 0.5 percent year over year in the first eight months of 2009, comparing favorably to Belarus’ main trading partners. Economic activity has been bolstered by strong domestic demand, especially for housing construction financed under government programs. Executive Directors have applauded the authorities’ commitment to a tight fisca...

  9. Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium

    OpenAIRE

    Pyne, Michael E.; Mark R. Bruder; Murray Moo-Young; Chung, Duane A; C. Perry Chou

    2016-01-01

    Application of CRISPR-Cas9 systems has revolutionized genome editing across all domains of life. Here we report implementation of the heterologous Type II CRISPR-Cas9 system in Clostridium pasteurianum for markerless genome editing. Since 74% of species harbor CRISPR-Cas loci in Clostridium, we also explored the prospect of co-opting host-encoded CRISPR-Cas machinery for genome editing. Motivation for this work was bolstered from the observation that plasmids expressing heterologous cas9 resu...

  10. The transition to E.M.U.: structural and strategic aspects

    OpenAIRE

    Michel Aglietta

    1995-01-01

    The recurrent crises in the EMS have bolstered a lively debate about the transition to EMU. Indeed the political economy of regional integration is at odds with the theory of optimum currency areas. Essentially static and based on real criteria alone, the latter is not suited to deal with a process which has historical roots, political ends, real and nominal dimensions. The relevant concept is convergence. ; Part I first discusses the interplay of nominal and real convergence, then examines t...

  11. STUDY ON CHEMICAL PARAMETER OF METEORITE IMPACT CRATER LAKE LONAR, INDIA.

    Directory of Open Access Journals (Sweden)

    Tandale M. R.

    2016-01-01

    Full Text Available Lonar Crater (19o58'N and 76o31'E Lake is the third biggest normal salt-water lake on the planet. Lonar Crater is a wet area which is vital biodiversity division. The lake saline solution bolsters run of the mill microbial verdure should be researched to get to its estimation of wet-area to be perceived as Ramsar Site of India.

  12. What Values Should Count in the Arts? The Tension between Economic Effects and Cultural Value

    OpenAIRE

    Frey, Bruno S.

    2005-01-01

    The basic distinction made in this volume compares ?economic value?, expressed in monetary terms, to ?cultural value?, reflecting cultural, aesthetic and artistic significance. This paper makes a different distinction which is rarely made explicit but which is of central importance to the decision process in cultural policy. On the one hand, ?value? is attached to the economic effects of cultural activities: When cultural values are created, economic activity is bolstered. The increase of com...

  13. Survival, Economic Mobility, and Community Among Los Angeles Fruit Vendors

    OpenAIRE

    Rosales, Rocio

    2012-01-01

    How do undocumented immigrants survive in a punitive regulatory environment? Drawing upon four years of ethnographic research, this article examines how local repressive policies affect the economic mobility of immigrant fruit vendors in Los Angeles County. In the face of government enforcement, fruit vendors have implemented strategies that allow for short-term survival but fail to bolster long-term upward mobility. The four survival strategies that I analyze include: 1) reliance on kinship ...

  14. Family-based prevention of mental health problems in children affected by HIV and AIDS: an open trial

    OpenAIRE

    Betancourt, Theresa Stichick; Ng, Lauren; Kirk, Catherine M.; Munyanah, Morris; Mushashi, Christina; Ingabire, Charles; Teta, Sharon; Beardslee, William Rigby; Brennan, Robert Thomas; Zahn, Ista; Stulac, Sara Nicole; Cyamatare, Felix R; Sezibera, Vincent

    2014-01-01

    Objective The objective of this study is to assess the feasibility and acceptability of an intervention to reduce mental health problems and bolster resilience among children living in households affected by caregiver HIV in Rwanda. Design Pre-post design, including 6-month follow-up. Methods The Family Strengthening Intervention (FSI) aims to reduce mental health problems among HIV-affected children through improved child–caregiver relationships, family communication and ...

  15. Simplified Negative Pressure Wound Therapy in Pediatric Hand Wounds

    OpenAIRE

    Kasukurthi, Rahul; Gregory H Borschel

    2009-01-01

    Negative pressure wound therapy (NPWT) is commonly used as a bolster for skin grafts. The technique offers the benefit of negative pressure as well as reduced dressing changes. Skin grafting of the hand provides a unique challenge, and currently, the only commercially available NPWT hand dressings are adult-sized, precluding their use in small children. We present our custom NPWT “mitten” technique for use with skin grafts on the pediatric hand.

  16. Wave Energy Conversion and Ocean Thermal Energy Conversion Potential in Developing Member Countries

    OpenAIRE

    Asian Development Bank

    2014-01-01

    Wave energy conversion (WEC) and Ocean thermal energy conversion (OTEC) are two potentially significant sources of renewable energy that are available to help the Asian Development Bank’s (ADB) developing member countries (DMCs) reduce their dependence on fossil-fuel based energy generation and bolster energy security. This report summarizes WEC and OTEC information that is available in the public domain for the DMCsand assesses the viability of using these resources to produce electricity. I...

  17. North Korea’s nuclear test

    OpenAIRE

    Radchenko, Sergey

    2009-01-01

    North Korea’s nuclear test serves several purposes. Its first purpose is to bolster the flagging legitimacy of the regime and, by drumming up war hysteria, achieve domestic mobilization in the face of mounting internal difficulties. Throughout North Korea’s turbulent history, the regime has periodically resorted to war hysteria, at times on even grander scale than what we have recently seen. North Korea’s Songun (army-first) policy requires periodic crises to maintain the myth of ...

  18. 鹿児島市の公立小学校における音楽教科に関する実態及び音楽と他教科との関連性についての考察(第2報)

    OpenAIRE

    新村, 元植; 川崎, 榮夫; シンムラ, ゲンショク; カワサキ, ヒデオ; Genshoku, Shimmura; Hideo, Kawasaki

    2010-01-01

    This second paper is a presentation of more extensive and detailed inquiry into relation between the musical training, learning of mathematics and Japanese language, carried among the pupils of 3rd through 6th grades of a municipal Elementary School in Kagoshima city. The results of this study have bolstered up the conclusions of our previous study. Namely, that the pupils who obtained better marks in music, had also better marks in mathematics and Japanese language.

  19. The Single Supervisory Mechanism – Panacea or Quack Banking Regulation? : Preliminary assessments of the evolving regime for the prudential supervision of banks with the ECB involvement (August 16, 2013)

    OpenAIRE

    Tröger, Tobias

    2013-01-01

    This paper analyzes the evolving architecture for the prudential supervision of banks in the euro area. It is primarily concerned with the likely effectiveness of the SSM as a regime that intends to bolster financial stability in the steady state. By using insights from the political economy of bureaucracy it finds that the SSM is overly focused on sharp tools to discipline captured national supervisors and thus under-incentives their top-level personnel to voluntarily contribute to rigid ...

  20. The Single Supervisory Mechanism - Panacea or Quack Banking Regulation? Preliminary assessment of the evolving regime for the prudential supervision of banks with ECB involvement

    OpenAIRE

    Tröger, Tobias

    2013-01-01

    This paper analyzes the evolving architecture for the prudential supervision of banks in the euro area. It is primarily concerned with the likely effectiveness of the SSM as a regime that intends to bolster financial stability in the steady state. By using insights from the political economy of bureaucracy it finds that the SSM is overly focused on sharp tools to discipline captured national supervisors and thus underincentives their top-level personnel to voluntarily contribute to rigid supe...

  1. The Single Supervisory Mechanism - Panacea or Quack Banking Regulation? : preliminary assessment of the evolving regime for the prudential supervision of banks with ECB involvement : [Version: 16 August 2013

    OpenAIRE

    Tröger, Tobias

    2013-01-01

    This paper analyzes the evolving architecture for the prudential supervision of banks in the euro area. It is primarily concerned with the likely effectiveness of the SSM as a regime that intends to bolster financial stability in the steady state. By using insights from the political economy of bureaucracy it finds that the SSM is overly focused on sharp tools to discipline captured national supervisors and thus underincentives their top-level personnel to voluntarily contribute to rigid supe...

  2. Volunteering in sport clubs

    OpenAIRE

    Nagel, Siegfried; Schlesinger, Torsten

    2014-01-01

    Volunteers are the most important resource for non-profit sport clubs seeking to bolster their viability (e.g. sporting programs). Although many people do voluntary work in sport clubs, stable voluntary engagement can no longer be granted. This difficulty is confirmed by existing research across various European countries. From a club management point of view, a detailed understanding of how to attract volunteers and retain them in the long term is becoming a high priority. The purpose of thi...

  3. Tilting toward immunosuppression

    OpenAIRE

    Hotchkiss, Richard S.; Coopersmith, Craig M.; McDunn, Jonathan E.; Ferguson, Thomas A.

    2009-01-01

    The immune response goes haywire during sepsis, a deadly condition triggered by infection. Richard S. Hotchkiss and his colleagues take the focus off of the prevailing view that the key aspect of this response is an exuberant inflammatory reaction. They assess recent human studies bolstering the notion that immunosuppression is also a major contributor to the disease. Many people with sepsis succumb to cardiac dysfunction, a process examined by Peter Ward. He showcases the factors that cause ...

  4. Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers

    OpenAIRE

    Warfield, Kelly L.; Swenson, Dana L.; Olinger, Gene G.; Nichols, Donald K; Pratt, William D.; Blouch, Robert; Stein, David A.; Aman, M. Javad; Iversen, Patrick L.; Bavari, Sina

    2006-01-01

    Synopsis Ebola virus (EBOV) causes a highly lethal hemorrhagic fever that results in up to 50%–90% mortality in humans. There are currently no available vaccines or therapeutics to treat EBOV infection. To date, multiple pre- and post-exposure therapeutic strategies, primarily focused on bolstering the host immune response or inhibiting viral replication, have been undertaken with limited success. Here, Bavari and colleagues report the development of a successful therapeutic regimen for EBOV ...

  5. Should knowledge of classical dance be essential for medical practitioners?

    Directory of Open Access Journals (Sweden)

    Shovana T Narayan

    2014-07-01

    Full Text Available The medical field is constantly throwing challenges, leading to considerable stress for its practitioners. Medical practitioners are expected to be professional, have up-to-date knowledge and expertise, and the ability to withstand fatigue. Through it all they are expected to remain motivated, respectful and humane, patient and kind, and confident and sensitive. The author demonstrates how learning dance can stimulate creativity, increase motivation and bolster social intelligence in medical practitioners.

  6. Instruments assessing motivation for change in eating disorders and their psychometric properties – a review.

    OpenAIRE

    2007-01-01

    Abstract Objective: Most patients with an eating disorder are not motivated to change their behavior. Prior research has demonstrated the prognostic value of a stages of change model in predicting outcome. Further, identifying the factors which influence an individual’s decision to change may bolster treatment effectiveness. An instrument with good reliability and validity for assessing motivation in eating disorders is necessary to correctly identify the patient’s motivational state. T...

  7. Rothbard’s and Hoppe’s justifications of libertarianism

    OpenAIRE

    Marian Eabrasu

    2013-01-01

    Murray N. Rothbard and Hans-Hermann Hoppe build their libertarian theory of justice on two axioms concerning self-ownership and homesteading, which are bolstered by two key arguments: reductio ad absurdum and performative contradiction. Each of these arguments is designed to demonstrate that libertarianism is the only theory of justice that can be justified. If either of these arguments were valid, it would prove the libertarian claim that the state is an unjust political arrangement. Giving ...

  8. The Myth of the Lone Physician: Toward a Collaborative Alternative

    OpenAIRE

    Saba, George W; Villela, Teresa J.; Chen, Ellen; Hammer, Hali; Bodenheimer, Thomas

    2012-01-01

    Cultural values and beliefs about the primary care physician bolster the myth of the lone physician: a competent professional who is esteemed by colleagues and patients for his or her willingness to sacrifice self, accept complete responsibility for care, maintain continuity and accessibility, and assume the role of lone decision maker in clinical care. Yet the reality of current primary care models is often fragmented, impersonal care for patients and isolation and burnout for many primary c...

  9. From Slash-and-burn to Disk Ploughing: The Land Policy and Tractors Behind Erosion and Forest Pioneer Farming in Southern Xayabury Province (Laos)

    OpenAIRE

    Marc Dufumier; Jean-Richard Laffort

    2013-01-01

    Bordering Thailand, the southern part of Xayabury province is engaged in international trade and has experienced agricultural growth like nowhere else in Laos. The rapid transformation from manual slash-and-burn agriculture to mechanized, chemical-based cropping systems is often cited by Laotian authorities as a model of development. But a careful study of changes underway indicates that the reality is far less encouraging than it would appear at first. If many farmers have indeed bolstered t...

  10. A mapping of ethnic entrepreneurship in Ireland

    OpenAIRE

    Cooney, Thomas; Flynn, Anthony

    2008-01-01

    The research findings presented in this report represent the first major attempt to map in a systematic fashion ethnic entrepreneurial activity in Ireland. The rapid transformation of the demographic profile of Ireland in this decade through unprecedented levels of immigration has stimulated debate on the economic and social policy implications of the new multi-racial Ireland. One facet to this policy debate is the potential for non-Irish nationals to bolster indigenous business activity. It ...

  11. H3ABioNet computational metagenomics workshop in Mauritius: training to analyse microbial diversity for Africa

    OpenAIRE

    Baichoo, Shakuntala; Botha, Gerrit; Jaufeerally-Fakim, Yasmina; Mungloo-Dilmohamud, Zahra; Lundin, Daniel; Mulder, Nicola; Promponas, Vasilis J.; Ouzounis, Christos A.

    2015-01-01

    In the context of recent international initiatives to bolster genomics research for Africa, and more specifically to develop bioinformatics expertise and networks across the continent, a workshop on computational metagenomics was organized during the end of 2014 at the University of Mauritius. The workshop offered background on various aspects of computational biology, including databases and algorithms, sequence analysis fundamentals, metagenomics concepts and tools, practical exercises, jou...

  12. The Doctrinal Method: Incorporating Interdisciplinary Methods in Reforming the Law

    OpenAIRE

    Hutchinson, Terry

    2015-01-01

    textabstractThe doctrinal methodology is in a period of change and transition. Realising that the scope of the doctrinal method is too constricting, academic lawyers are becoming eclectic in their use of research method. In this transitional time, legal scholars are increasingly infusing evidence (and meth- ods) from other disciplines into their reasoning to bolster their reform recommendations. This article considers three examples of the interplay of the discipline of law with other discipl...

  13. Challenges, Growth and Opportunity: A Shadow Federal Budget for 2015

    OpenAIRE

    William B.P. Robson; Alexandre Laurin

    2015-01-01

    The 2015 edition of the C.D. Howe Institute’s annual Shadow Federal Budget lays out a prudent fiscal course in the face of a challenging world economic environment, bolstering the confidence of Canadians in the sustainability of their public finances. It supports economic growth with tax changes and investments that support business investment and job creation. And it enhances opportunities for Canadians by investing in their skills for the workplace and better preparing them for retirement. ...

  14. In the balance

    DEFF Research Database (Denmark)

    Kluth, Michael Friederich; Pilegaard, Jess

    The present paper seeks to make sense of recent EU naval capability changes by applying neo-realist theory on the EU as an international actor in the global balance of power. The paper compares three different strands of Neo-realist theory by deducting key predictions about the expected defense...... strategy aimed at bolstering the autonomy and international influence of the Union, vis-à-vis other major powers, including the United States....

  15. CALIMACO: desarrollo de un servicio de bibliotecario virtual para la interacción multimodal con dispositivos móviles

    OpenAIRE

    Griol, David; Patricio, Miguel Ángel; Molina, José Manuel

    2016-01-01

    In recent years smart mobile devices have bolstered new interaction scenarios that require more sophisticated human-machine interfaces. The leading developers of operating systems for these devices now provide APIs (Application Programming Interface) for developers to implement their own applications, including different solutions for developing graphical interfaces, control sensors and providing oral interaction. Despite the usefulness of these resources, defined strategies are still needed ...

  16. Unlocking the 'Triple Dividend' of Resilience : Why Investing in Disaster Risk Management Pays Off

    OpenAIRE

    Overseas Development Institute; World Bank Group

    2015-01-01

    The risk of a disaster can cause economic losses even before a disaster strikes. Investing in disaster resilience, therefore, can yield a ‘triple dividend’ by (1) avoiding losses when disasters strike; (2) unlocking development potential by stimulating innovation and bolstering economic activity in a context of reduced disaster-related background risk for investment; and (3) through the synergies of the social, environment and economic co-benefits of disaster risk ...

  17. The EU policy on institutional multilingualism: between policy and practicality

    OpenAIRE

    Baaij, C.J.W.

    2012-01-01

    This article brings to light several inconsistencies within the narrative of the EU policy on institutional multilingualism. The EU has invoked fundamental EU principles of democracy, equality and transparent government, to publically bolster the need for its institutions to communicate and operate in the languages of its citizens. However, these principles do not allow for the pragmatic and budgetary arguments that the EU uses to justify the in reality limited number of official and de facto...

  18. Coastal and marine ecosystem services valuation for policy and management

    OpenAIRE

    Luisetti, Tiziana; Turner, R. Kerry; Hadley, David; Morse-Jones, Sian

    2010-01-01

    Understanding the economic value of nature and the services it provides to humanity has become increasingly important. In this paper we review the progress to date on both the necessary conceptual framework and empirical valuation studies required to bolster decision support systems targeted at integrated coastal zone management goals. We first review definitions of ecosystem services. We then highlight and discuss the importance of: spatial explicitness; marginal changes; double-counting; no...

  19. Effects of Terrestrial Buffer Zones on Amphibians on Golf Courses

    OpenAIRE

    Puglis, Holly J.; Boone, Michelle D.

    2012-01-01

    A major cause of amphibian declines worldwide is habitat destruction or alteration. Public green spaces, such as golf courses and parks, could serve as safe havens to curb the effects of habitat loss if managed in ways to bolster local amphibian communities. We reared larval Blanchard's cricket frogs (Acris blanchardi) and green frogs (Rana clamitans) in golf course ponds with and without 1 m terrestrial buffer zones, and released marked cricket frog metamorphs at the golf course ponds they w...

  20. Republic of Tajikistan; Third Review Under the Three-Year Arrangement Under the Extended Credit Facility, Request for Waiver of Nonobservance of a Performance Criterion and Request for Modification of a Performance Criterion-Staff Report; Staff Supplements; Press Release on the Executive Board Discussion.

    OpenAIRE

    International Monetary Fund

    2010-01-01

    Economic activity is on the upswing in Tajikistan, bolstered by higher hydroelectric power production. The government is working to address the structural energy deficit and achieve energy independence, raise social expenditures, maintain a flexible exchange rate regime, and continue structural reforms. Medium-term fiscal consolidation will be essential while striking a careful balance between social and capital spending. Macroeconomic policies should shift from an anti-crisis to a post-crisi...

  1. Rayleigh-Sommerfeld diffraction and Poisson's spot

    International Nuclear Information System (INIS)

    When the Fresnel-Kirchhoff (FK) diffraction integral is evaluated exactly (instead of using the Fresnel approximation), the well-known mathematical inconsistency in the FK boundary conditions leads to unacceptable results for the intensity of Poisson's spot. The Rayleigh-Sommerfeld (RS) integral has no inconsistencies and leads to an accurate description. The case for RS is bolstered by the observation that it is equivalent to Fourier propagation

  2. Current practices and guidelines for clinical next-generation sequencing oncology testing

    Institute of Scientific and Technical Information of China (English)

    Samuel P. Strom

    2016-01-01

    Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadth genomic of information available to oncologists and their patients. This review will explore the ways in which this new technology is currently applied to bolster care for patients with solid tumors and hematological malignancies, focusing on practices and guidelines for assessing the technical validity and clinical utility of DNA variants identified during clinical NGS oncology testing.

  3. How the Great Firewall of China is Blocking Tor

    OpenAIRE

    Winter, Philipp; Lindskog, Stefan

    2012-01-01

    Internet censorship in China is not just limited to the web: the Great Firewall of China prevents thousands of potential Tor users from accessing the network. In this paper, we investigate how the blocking mechanism is implemented, we conjecture how China's Tor blocking infrastructure is designed and we propose circumvention techniques. Our work bolsters the understanding of China's censorship capabilities and thus paves the way towards more effective circumvention techniques.

  4. The emerging study of positive empathy

    OpenAIRE

    Morelli, SA; Lieberman, MD; Zaki, J

    2015-01-01

    © 2015 John Wiley & Sons Ltd. Lay intuitions suggest that the ability to share, celebrate, and enjoy others' positive emotions - a phenomenon we term positive empathy - bolsters individual well-being and relationship strength. However, it is unclear from the current literature whether (i) positive empathy is distinct from highly related constructs and (ii) whether positive empathy is associated with salutary social and personal outcomes. Here, we begin by examining basic evidence suggesting t...

  5. A pilot feasibility study of a peer-led mindfulness program for medical students

    OpenAIRE

    Danilewitz, Marlon; Bradwejn, Jacques; Koszycki, Diana

    2016-01-01

    Background Mindfulness meditation has gained momentum in medical circles for bolstering wellbeing and other facets of professionalism. This study evaluated the feasibility and benefits of a peer-led mindfulness meditation program (MMP) on medical student wellness and professionalism. Method Pre-clerkship students were recruited and randomized to the 8-week MMP or wait-list. Feasibility outcomes included ease of recruitment, program attendance and homework compliance. Other outcomes included s...

  6. Children, healthy eating and “threat appeals” : An investigation on their effectiveness and working processes

    OpenAIRE

    Charry, Karine

    2009-01-01

    This dissertation aimed at identifying the potential effectiveness of threat appeals in advertising communication when bolstering preadolescents’ consumptions of healthy food is considered. Obesity indeed appears as one of the main health issue for this population (8- to 12-year-olds) in our western societies. Although many prevention programs are being developed, very few appear to achieve the behavioral changes expected. Associating research on advertising persuasion among preadolescents...

  7. MARKET WATCH

    Institute of Scientific and Technical Information of China (English)

    HU YUE

    2011-01-01

    Greater Use of the Yuan In a bid to bolster the global presence of the yuan,China has expanded its yuan settlement program in cross-border trade to cover the entire nation.In July 2009,China launched the pilot program in five cities including Shanghai and Guangzhou.The mechanism was widened to cover 20 provinces,municipalities and autonomous regions across the country in June 2010.

  8. Řízení lidských zdrojů v období hospodářské recese v energetických společnostech

    OpenAIRE

    Mladonický, Jakub

    2015-01-01

    Mladonický, J. Human resources management in energetics during Great Recession. Diploma thesis. Brno Mendel University in Brno, 2014. Remuneration with motivation theory is one of the most important areas in human resources management. The Great Recession theirs status only bolster up. This work was aimed to make a suggestion for lowering the impact to human resources using remuneration as motivation factor during economic crisis. Analysis of remuneration and labour productivity in energetics...

  9. Improving the Efficacy of Appearance-Based Sun Exposure Interventions with the Terror Management Health Model

    OpenAIRE

    Morris, Kasey Lynn; Cooper, Douglas P.; Goldenberg, Jamie L.; Arndt, Jamie; Gibbons, Frederick X.

    2014-01-01

    The terror management health model (TMHM) suggests that when thoughts of death are accessible people become increasingly motivated to bolster their self-esteem relative to their health, because doing so offers psychological protection against mortality concerns. Two studies examined sun protection intentions as a function of mortality reminders and an appearance-based intervention. In Study 1, participants given a sun protection message that primed mortality and shown a UV-filtered photo of t...

  10. The Influence of Concentrative Meditation Training on the Development of Attention Networks during Early Adolescence

    Directory of Open Access Journals (Sweden)

    Shruti eBaijal

    2011-07-01

    Full Text Available We investigate if concentrative meditation training (CMT offered during adolescent development benefits subsystems of attention using a quasi-experimental design. Attentional alerting, orienting, and conflict monitoring were examined using the Attention Network Test (ANT in 13, 14, and 15 yo children who received CMT as part of their school curriculum (CMT Group: N=79 vs. those who received no such training (Control Group: N=76. Alerting and conflict monitoring, but not orienting, differed between the CMT and Control Group. Only conflict monitoring demonstrated age-related improvements, with smaller conflict effect scores in older vs. younger participants. The influence of CMT on this system was similar to the influence of developmental maturity, with smaller conflict effects in the CMT vs. Control group. To examine if CMT might also bolster conflict-triggered upregulation of attentional control, conflict effects were evaluated as a function of previous trial conflict demands (high conflict vs. low conflict. Smaller current trial conflict effects were observed when previous conflict was high vs. low, suggesting that similar to adults, when previous conflict was high (vs. low children in this age-range proactively upregulated control so that subsequent trial performance was benefitted. The magnitude of conflict-triggered control upregulation was not bolstered by CMT but CMT did have an effect for current incongruent trials preceded by congruent trials. Thus, CMT’s influence on attention may be tractable and specific; it may bolster attentional alerting, conflict monitoring and reactive control, but does not appear to improve orienting.

  11. Applying a Family-Level Economic Strengthening Intervention to Improve Education and Health-Related Outcomes of School-Going AIDS-Orphaned Children: Lessons from a Randomized Experiment in Southern Uganda.

    Science.gov (United States)

    Ssewamala, Fred M; Karimli, Leyla; Torsten, Neilands; Wang, Julia Shu-Huah; Han, Chang-Keun; Ilic, Vilma; Nabunya, Proscovia

    2016-01-01

    Children comprise the largest proportion of the population in sub-Saharan Africa. Of these, millions are orphaned. Orphanhood increases the likelihood of growing up in poverty, dropping out of school, and becoming infected with HIV. Therefore, programs aimed at securing a healthy developmental trajectory for these orphaned children are desperately needed. We conducted a two-arm cluster-randomized controlled trial to evaluate the effectiveness of a family-level economic strengthening intervention with regard to school attendance, school grades, and self-esteem in AIDS-orphaned adolescents aged 12-16 years from 10 public rural primary schools in southern Uganda. Children were randomly assigned to receive usual care (counseling, school uniforms, school lunch, notebooks, and textbooks), "bolstered" with mentorship from a near-peer (control condition, n = 167), or to receive bolstered usual care plus a family-level economic strengthening intervention in the form of a matched Child Savings Account (Suubi-Maka treatment arm, n = 179). The two groups did not differ at baseline, but 24 months later, children in the Suubi-Maka treatment arm reported significantly better educational outcomes, lower levels of hopelessness, and higher levels of self-concept compared to participants in the control condition. Our study contributes to the ongoing debate on how to address the developmental impacts of the increasing numbers of orphaned and vulnerable children and adolescents in sub-Saharan Africa, especially those affected by HIV/AIDS. Our findings indicate that innovative family-level economic strengthening programs, over and above bolstered usual care that includes psychosocial interventions for young people, may have positive developmental impacts related to education, health, and psychosocial functioning. PMID:26228480

  12. NF-kappaB in Lung Tumorigenesis

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Zhenjian [Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, 462 First Avenue, NBV 7N24, New York, NY 10016 (United States); Tchou-Wong, Kam-Meng; Rom, William N., E-mail: william.rom@nyumc.org [Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, 462 First Avenue, NBV 7N24, New York, NY 10016 (United States); Department of Environmental Medicine, New York University School of Medicine, 57 Old Forge Road, Tuxedo, NY 10987 (United States)

    2011-12-14

    The development of lung cancer in humans can be divided into three steps initiation, promotion and progression. This process is driven by alterations in related signal transduction pathways. These pathways signal the aberrant activation of NF-kappaB, a transcription factor that regulates the expression of genes important for lung tumorigenesis. Our current knowledge about the role of the NF-kappaB signaling pathway in the development of lung cancer has been bolstered by animal models demonstrating the connection between K-ras and tobacco induced lung transformation with NF-kappaB. Activation of downstream genes leads to cell proliferation, inhibition of apoptosis, angiogenesis, inflammation, invasion, and metastasis.

  13. Continuity and Rupture in the Growth of Cultures

    Directory of Open Access Journals (Sweden)

    Jaume Botey Vallès

    1997-05-01

    Full Text Available The first part of the article deals with the classical concepts of identity, diversity and pluralism in relation to present societies in conflict. The second part addresses specifically the case of the Andalusian immigration to Catalonia from 1955 to 1975 and the hardening relations and tensions between the two communities in present-day Catalonia. Finally, in the presence of economic globalization and the bolstered emergence of new identities, some of which have religious aspects as significant components, a proposition is put forth to find common ground in the new social movements and religious faith as two arenas of intercultural negotiation.

  14. Countering the lingering threat of the Abu Sayyaf group

    OpenAIRE

    Cohn, Stephen C.

    2007-01-01

    This thesis will argue that the most effective strategy for eradicating the U.S. designated Foreign Terrorist Organization, the Abu Sayyaf Group (ASG), is to bolster the current peace talks between the Republic of the Philippines and the Moro Islamic Liberation Front (MILF). The MILF has been providing support and sanctuary to the ASG which has hindered U.S.-Philippine counter-terror operations. This thesis will explain why a shift in U.S.-Philippine strategy is required by examining what...

  15. Implementation Of 5S Quality Tool In Manufacturing Company A Case Study

    Directory of Open Access Journals (Sweden)

    Vibhor Kakkar

    2015-02-01

    Full Text Available Abstract 5S system is a technique which maintains the quality of working conditions in the organization. Amongst various available Lean resources 5S is a powerful technique that can bolster objectives of the organization to get continuous improvement in performance and productivity. This paper presents the implementation of 5S in a manufacturing company amp 5S rating system was used to audit all changes in the company which enhanced the efficiency of the workers amp ultimately the productivity of the company is enhanced to 91 .

  16. Metathesis access to monocyclic iminocyclitol-based therapeutic agents

    Directory of Open Access Journals (Sweden)

    Albert Demonceau

    2011-05-01

    Full Text Available By focusing on recent developments on natural and non-natural azasugars (iminocyclitols, this review bolsters the case for the role of olefin metathesis reactions (RCM, CM as key transformations in the multistep syntheses of pyrrolidine-, piperidine- and azepane-based iminocyclitols, as important therapeutic agents against a range of common diseases and as tools for studying metabolic disorders. Considerable improvements brought about by introduction of one or more metathesis steps are outlined, with emphasis on the exquisite steric control and atom-economical outcome of the overall process. The comparative performance of several established metathesis catalysts is also highlighted.

  17. Joomla! 25 Beginner's Guide

    CERN Document Server

    Tiggeler, Eric

    2012-01-01

    Written with a fast-paced but friendly and engaging approach, this Packt Beginner's guide is designed to be placed alongside the computer as your guide and mentor. Step-by-step tutorials are bolstered by explanations of the reasoning behind what you are doing. You will quickly pick up the necessary skills, tips, and tricks for building a successful Joomla! website. This book is written for beginners to website design. By the end of the book you will have built a complete custom content managed website, and be ready to build any kind of website.

  18. Discovering and exploring ubuntu-language in the dialogue between the Dutch Reformed Church and the Uniting Reformed Church in Southern Africa

    Directory of Open Access Journals (Sweden)

    Lieze Meiring

    2015-06-01

    Full Text Available Discussions with members of the Dutch Reformed Church (DRC and the Uniting Reformed Church in Southern Africa (URCSA in Ohrigstad illustrate the possibilities of ubuntu-language in overcoming racism and prejudice. After proposing a number of meanings and values related to ubuntu, this research explores the role of ubuntu-language � and at times the lack thereof � in the concrete relationship between these two faith communities as an expression of recent South African history. Ubuntu-language seems to offer unique outcomes in this relationship in strengthening identity, unleashing vitality, celebrating diversity, awakening solidarity, revealing humanity, bolstering individualism and enhancing Christianity.

  19. Instant Citrix security how-to

    CERN Document Server

    Jacob, Carmel

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Get the job done and learn as you go. A how-To book with practical recipes accompanied with rich screenshots for easy comprehension.This easy-to-follow, hands-on guide shows you how to bolster your security with real life cases and step-by-step instructions.This guide gets new users up and running with Citrix Netscaler in simple practical steps and also acts as a refresher to those with some experience of the product and its features.

  20. Fronteira, fusão, filme: um toque

    Directory of Open Access Journals (Sweden)

    Tunico Amancio

    2010-12-01

    Full Text Available Considered the first co-production between MERCOSUR countries, "The touch of the Oboe", a film by Claudio MacDowell, suffers from some sort of vagueness that shows off the difficulties of a complete commercial and cultural movie exchange between Brazil's neighbor countries. Even bolstered with powerful traditions, the productive associative project of this cinematic realization emblematizes an economical, symbolical and historical imbalance which still prevails among the countries of the Southern Common Market. The text notes some of these tensions, marked by the relationship between cinema and literature.

  1. Adam Smith and the Invisible Hand: From Metaphor to Myth

    OpenAIRE

    Gavin Kennedy

    2009-01-01

    Adam Smith and the ‘invisible hand’ are nearly synonymous in modern economic thinking. Adam Smith is strongly associated with the invisible hand, understood as a general rule that people in realising their self-interests unintentionally benefit the public good. The attribution to Smith is challengeable. Adam Smith’s use of the metaphor was much more modest; it was re-invented in the 1930s and 1940s onwards to bolster mathematical treatments of capitalism (Samuelson, Friedman) and to sup...

  2. IDEOLOGICAL CONNOTATIONS OF THE INSCRIPTIONS OF JUMA MASJED OF ISFAHAN

    OpenAIRE

    Ghada Abdel Monem El Gemaiey

    2014-01-01

    This paper refers to the role of sacred texts in defining a building by using some texts more than others, by highlight some issues in a context while skip others, or by adopting references from the Quran or Hadith to bolster certain beliefs. The sacred texts in this mosque depend mostly on the Shiites Imams’ speech, some from Hadith of Prophet Muhammad, and the minority of the sacred texts is taken from the Quran. Minority here is not in terms of quantity but in using the context to co...

  3. The Legacy of the Khmer Rouge Tribunal: Maintaining the Status Quo of Cambodia's Legal and Judicial System

    Directory of Open Access Journals (Sweden)

    Sana Ghouse, John Coughlan, Richard Smith

    2012-05-01

    Full Text Available

    The Cambodian judicial system is fraught with deficiencies. The Extraordinary Chambers in the Courts of Cambodia – established to try the leaders of the Khmer Rouge and those most responsible for the atrocities committed during the regime – has been hailed as a model court from which to bolster domestic legal and judicial reform. While the ECCC has made some steps towards providing a positive legacy - enhancing the capacity of the judiciary, addressing fair trial rights and standards of justice - in the absence of political will to address corruption and political interference, this legacy is superficial at best.

  4. The crisis of 1866

    OpenAIRE

    Flandreau, Marc; Ugolini, Stefano

    2014-01-01

    The collapse of Overend Gurney and the ensuing Crisis of 1866 was a turning point in British financial history. The achievement of relative stability was due to the Bank of England´s willingness to offer generous assistance to the market in a crisis, combined with an elaborate system for maintaining the quality of bills in the market. We suggest that the Bank bolstered the resilience of the money market by monitoring leverage-building by money market participants and threatening exclusion fro...

  5. "We live on earth : rotating systems" : performance by J. Jarosz (PL) done at the Physics on Stage Festival

    CERN Multimedia

    CERN Audiovisual Service

    2000-01-01

    Part of the Physics on Stage Festival (04-10 November 2000). During this event, the national competion winners, science teachers, science communicators, publishers, top scientists and high-level representatives of the ministries and European organisations will brainstorm future solutions to bolster physics' popularity. The programme will also include spectacular demonstrations of new educational tools; the best will be disseminated over the national TV networks and other media to the European public. A the end of the film, Dutch Performance by The Eindhoven Circus of Physics, Prof. De Waele from the Eindhoven University of Technology

  6. Are Your Employees Retirement-Ready?

    Science.gov (United States)

    Vorchheiner, Alan H; Zaleta, Cynthia O

    2016-01-01

    Much of the discussion on the decumulation phase of retirement savings has focused on the lack of any lifetime annuities. But there is a whole range of options sponsors can employ to facilitate the generation of retirement income and bolster financial wellness. As U.S. employers show no sign of substantially increasing spending on compensation or benefits, it is imperative that human resources professionals help employees--particularly the retiring baby boomers--to maximize what they have saved. This article presents five first-step ideas toward achieving that goal. PMID:27017793

  7. Innovations in plant health services in Nicaragua

    DEFF Research Database (Denmark)

    Danielsen, Solveig; Centeno, Julio; López, Julio;

    2013-01-01

    creation of a ‘National Plant Health System’ offering regular advice to farmers. The innovations were driven by a momentum for change, committed individuals, joint learning and flexibility in programme management. External facilitation encouraged experimentation and bolstered growth of new alliances. The......Establishing a few community-based plant clinics in Nicaragua led to a series of innovations in plant health service delivery. A grassroots experiment became a nationwide initiative involving local service providers, universities, research institutions and diagnostic laboratories. This led to the...... development of the national plant health system was constrained by existing work cultures that limit the scope of individual and institutional innovations....

  8. Practice stories in natural resource management continuing professional education: springboards for learning

    DEFF Research Database (Denmark)

    Stummann, Cathy Brown

    2014-01-01

    supporting professional learning of new concepts. These uses of practice stories are not evident in public natural resource management (NRM) continuing professional education. In light of greater public involvement in NRM practice over the last 20 years, however, the use of practice stories could now be......The use of stories from professional experience in continuing professional education has been on the rise in many fields, often aimed at bolstering capacity through sharing professional knowledge and/or supporting reflective practice. Practice stories are also suggested to be beneficial in...

  9. Education and Training in Radiochemistry -- The NAMP Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Patricia Paviet-Hartmann; Mansour Akbarzadeh

    2013-07-01

    A number of reports have indicated that a sizable percentage of the nation’s experts in radiochemistry are nearing retirement age. This reality has been a concern since the 1970s, when declining numbers of radiochemists worldwide was first observed. Therefore, the NAMP (National Analytical Management Program) has organized a subcommittee focused on training and education in radiochemistry. To bolster interest and increase awareness in radiochemistry, NAMP is offering webinars developed by experts on different topics relevant to radiochemistry. This paper presents our accomplishments in developing these webinars and highlights our efforts in outreaching the national and international radiochemistry community.

  10. Green shopping

    DEFF Research Database (Denmark)

    Thøgersen, John

    2011-01-01

    Findings suggesting that consumers buy “green” products, such as organic foods, for selfish reasons are usually accepted at face value. In this article, the author argues that the evidence backing this claim is questionable and that it reflects post hoc rationalizations and self-presentation biases......’s beliefs about intangible private benefits in a way that justifies (bolsters) one’s purchasing decision. A survey study among a representative sample of approximately 4,000 respondents from four European countries (Denmark, Germany, United Kingdom, and Italy) confirmed that this is exactly what “green...

  11. Capable of Suicide: A Functional Model of the Acquired Capability Component of the Interpersonal-Psychological Theory of Suicide

    Science.gov (United States)

    Smith, Phillip N.; Cukrowicz, Kelly C.

    2016-01-01

    The current review aims to present a functional model of the acquired capability for suicide; a component of Joiner’s (2005) Interpersonal-Psychological Theory of Suicide. This review is aimed at integrating the points discussed by Joiner into a unified and specific conceptualization of acquired capability. Additionally, we offer some points of elaboration; such as the interaction between specific diatheses with life events, the role of short-term bolstering of the capability for suicide, and how contextual factors moderate the experience of painful and provocative life events; thereby leading to fearlessness and pain insensitivity to the actions and ideas involved in suicide. PMID:20560748

  12. Cost-time management: A powerful tool in a new application - cleaning up the weapons complex

    International Nuclear Information System (INIS)

    Westinghouse Electric Corporation is aggressively applying cost-time management to bolster timely, cost-effective cleanup and waste management activities at sites it manages for the U.S. Department of Energy (DOE). Cost-time management is a diagnostic technique which is applicable to virtually any process. It identifies opportunities to reduce cycle-times and costs. When applied to cleanup and waste management at DOE facilities, cost-time profile analysis helps identify actions to improve productivity and quality. Moreover, by reducing cycle-times and costs, it achieves significant savings to taxpayers. (author)

  13. Onshoring: An i-Opener for Apple, Inc.

    OpenAIRE

    Mr. Francisco Javier Salazar; Dr. Ryan Lunsford

    2014-01-01

    The December 2012 announcement from Apple, Inc.’s CEO Tim Cook that the company intends to move the production of its Mac computer lines to the United States is interesting on several levels. Cook acknowledged that the move is influenced, at least in part, by a desire to bolster a sluggish U.S. unemployment rate that continues to hover around 8% (Gross, 2012). There was no mention of where the company might be locating its facilities at the time of the announcement, “but bringing assembly-lin...

  14. Tilting toward immunosuppression

    Science.gov (United States)

    Hotchkiss, Richard S.; Coopersmith, Craig M.; McDunn, Jonathan E.; Ferguson, Thomas A.

    2013-01-01

    The immune response goes haywire during sepsis, a deadly condition triggered by infection. Richard S. Hotchkiss and his colleagues take the focus off of the prevailing view that the key aspect of this response is an exuberant inflammatory reaction. They assess recent human studies bolstering the notion that immunosuppression is also a major contributor to the disease. Many people with sepsis succumb to cardiac dysfunction, a process examined by Peter Ward. He showcases the factors that cause cardiomyocyte contractility to wane during the disease. PMID:19424209

  15. ISES International Solar Energy Society: Italian Section report. Rapporto del Comitato Energia Eolica della Sezione Italiana dell'ISES: Comitati di lavoro ISES

    Energy Technology Data Exchange (ETDEWEB)

    Sesto, E.; Stancampiano, M.

    After a brief introduction highlighting the potential benefits to be derived from the suitable application of wind turbines, in terms of economic and environmentally compatible energy supplies for remote areas, this paper gives a panoramic look at wind turbine commercialization activities in Italy. The main manufacturers and technical characteristics of the three most promising wind turbines are reported. Comments are made on world market trends and incentive programs being developed by the Italian Government and the European Communities to help bolster industrial participation in this sector.

  16. Philippines' downstream sector poised for growth

    International Nuclear Information System (INIS)

    This paper reports that the Philippines' downstream sector is poised for sharp growth. Despite a slip in refined products demand in recent years, Philippines products demand will rebound sharply by 2000, East-West Center (EWC), Honolulu, predicts. Philippines planned refinery expansions are expected to meet that added demand, EWC Director Fereidun Fesharaki says. Like the rest of the Asia-Pacific region, product specifications are changing, but major refiners in the area expect to meet the changes without major case outlays. At the same time, Fesharaki says, push toward deregulation will further bolster the outlook for the Philippines downstream sector

  17. Arte e identità nazionale. Riflessioni sul caso italiano

    OpenAIRE

    Corgnati, Martina

    2011-01-01

    Artists have played an important role in representations and reflections on the “idea of Italy” from the Risorgimento to the present day.  The Garibaldian, monarchical, and liberal currents of the movement for unification were figured in patriotic scenes and symbols, as were the disappointments with the political realities of the new Italian kingdom.  In the twentieth century the “mission” of a “pure” Italian art to bolster identification with the nation (and with the ruling regime) is repeat...

  18. Causal influence in neural systems: Reconciling mechanistic-reductionist and statistical perspectives. Comment on "Foundational perspectives on causality in large-scale brain networks" by M. Mannino & S.L. Bressler

    Science.gov (United States)

    Griffiths, John D.

    2015-12-01

    The modern understanding of the brain as a large, complex network of interacting elements is a natural consequence of the Neuron Doctrine [1,2] that has been bolstered in recent years by the tools and concepts of connectomics. In this abstracted, network-centric view, the essence of neural and cognitive function derives from the flows between network elements of activity and information - or, more generally, causal influence. The appropriate characterization of causality in neural systems, therefore, is a question at the very heart of systems neuroscience.

  19. Financial Planning and Financial Instruments: 2013 in Review, 2014 in Prospect

    Directory of Open Access Journals (Sweden)

    Mark Brimble

    2013-09-01

    Full Text Available The Global Financial Crisis (GFC; changes in regulation; issues in public perception and trust have contributed to a troubled 2013 for financial planners. As financial planning and wealth management providers seek to bolster their professional status, the Financial Planning Education Council’s National Curriculum and Accreditation Framework and ASIC’s minimum training requirements are also a space to watch. In prospect, 2014 will offer opportunities and challenges in the form of a changed government; regulatory changes; accreditation challenges and the hope of the recruitment of strong financial planning and wealth management professionals for the future.

  20. Globalization Crises, Trade,and Development in Vietnam

    DEFF Research Database (Denmark)

    Abbott, Philip; Tarp, Finn

    Vietnam has been among the most successful East Asian economies, especially in weathering the external shocks of recent globalization crises—the 1997-98 Asian financial crisis and the 2008-09 great recession, financial crisis and collapse of global trade. Its success contradicts its...... dependence and bolster the domestic economy while continuing to restructure the economy toward greater emphasis on the private sector. Growth, employment and poverty alleviation have been maintained at the expense of renewed inflation, larger budget deficits, and currency depreciation. The ‘stop-go’ nature...

  1. CERN and the Wigner Research Centre for Physics inaugurate CERN data centre’s extension in Budapest, Hungary

    CERN Multimedia

    Wigner Research Centre for Physics, Hungary

    2013-01-01

    On 13 June 2013 CERN and the Wigner Research Centre for Physics inaugurated the Hungarian data centre in Budapest, marking the completion of the facility hosting the extension for CERN computing resources. About 500 servers, 20,000 computing cores, and 5.5 Petabytes of storage are already operational at the site. The dedicated and redundant 100 Gbit/s circuits connecting the two sites are functional since February 2013 and are among the first transnational links at this distance. The capacity at Wigner will be remotely managed from CERN, substantially extending the capabilities of the Worldwide LHC Computing Grid (WLCG) Tier-0 activities and bolstering CERN’s infrastructure business continuity.

  2. Comparison of the Transport of Tetracycline-Resistant and Tetracycline-Susceptible Escherichia coli Isolated from Lake Michigan

    OpenAIRE

    Walczak, Jacob J.; Bardy, Sonia L.; Feriancikova, Lucia; Xu, Shangping

    2011-01-01

    It was recently reported that tetracycline could enhance the mobility of manure-derived Escherichia coli within saturated porous media (Walczak et al. (Water Research 45:1681–1690, 2011)). It was also shown, however, that E. coli from various sources could display marked variation in their mobility (Bolster et al. (Journal of Environmental Quality 35:1018–1025, 2009)). The focus of this research was to examine if the observed difference in the mobility of manure-derived tetracycline-resistant...

  3. Immunity challenge.

    Science.gov (United States)

    Davenport, R John

    2003-06-11

    As people get older, their immune systems falter. The elderly are more susceptible to infections than youngsters are, and hyperactive inflammatory responses appear to contribute to some age-associated illnesses, including Alzheimer's disease and atherosclerosis. Investigating the effect of aging on the immune system was once a scientific stepchild, but card-carrying immunologists are now tackling the problem head-on. Despite the immune system's complexity, researchers have started to make sense of how its components change with age. As the research progresses, scientists hope to bolster elderly people's response to infectious diseases and quiet the inflammation that can make aging a painful experience. PMID:12844525

  4. In Search of the jüdische Typus: A Proposed Benchmark to Test the Genetic Basis of Jewishness Challenges Notions of “Jewish Biomarkers”

    OpenAIRE

    Elhaik, E.

    2016-01-01

    The debate as to whether Jewishness is a biological trait inherent from an “authentic” “Jewish type” (jüdische Typus) ancestor or a system of beliefs has been raging for over two centuries. While the accumulated biological and anthropological evidence support the latter argument, recent genetic findings, bolstered by the direct-to-consumer genetic industry, purport to identify Jews or quantify one’s Jewishness from genomic data. To test the merit of claims that Jews and non-Jews are genetical...

  5. Visions of Mughal India: An Anthology of European Travel Writing. London, I.B. Tauris, 2007, 256 p.

    OpenAIRE

    Mitchell, Colin P.

    2013-01-01

    ed. Our understanding of Mughal India is to no small degree bolstered by a significant number of European travel accounts produced in the 16th-18th centuries. While we depend on court chronicles and religio-philosophical treatises to better understand the ‘elite’ narrative of Mughal India, the day-to-day, quotidian details of life in early modern South Asia are largely absent in such ‘indigenous’ documents. For this reason, historians of social, gender, urban and economic history are often dr...

  6. A Robust Environmental Sound Recognition System using BPNN and RBFNN

    Directory of Open Access Journals (Sweden)

    T.Sivaprakasam

    2014-12-01

    Full Text Available In a reverberant environment, the performance of acoustic event recognition system can be bolstered by choosing appropriate feature descriptors and classifier techniques. Neural networks are by far providing stunning classification results when compared to other classifiers. This paper analyses two different neural networks and their precision when they both stumble upon same targets in similar environment. The analysis is done on back propagation neural network (BPNN and radial basis function neural network (RBFNN with same dataset and then a conclusion is formed on the basis of their performance and efficiency. The experiments on various categories illustrate that the results of recognition for BPNN are significant and effective.

  7. Nuclear waste dumping in the oceans: Has the Cold War taught us anything?

    International Nuclear Information System (INIS)

    The United States and other international actors have relied without much success on traditional approaches to contain environmental damage done to our oceans by Russian dumping of nuclear waste. Our arms control experience suggests that on-site inspection is successful in situations where there is a lack of information or a lack of trust. Using on-site inspection to gather information and bolster trust could ameliorate the problem of Russian dumping of radioactive wastes into the ocean, so long as the political and financial costs of on-site inspection do not prove to be prohibitively high

  8. Insights into the Ukrainian Crisis

    Directory of Open Access Journals (Sweden)

    Costel Daniel Arfire

    2014-05-01

    Full Text Available Political crises are increasingly frequent and devastating not only for the population of a state, but also for the international diplomacy. Such an example is the ongoing Ukrainian crisis. Starting from S. Fink‘s life cycle of a crisis and T.W. Coombs‘s crisis response strategies, I will analyse the evolution of the Ukrainian crisis and the crisis response strategies of three major international actors: Vladimir Putin, Barack Obama and Angela Merkel. The findings of my study will prove that the denial strategy prevails in Putin‘s statement, whereas Obama uses the diminish strategy and Merkel focuses on the bolstering strategy.

  9. 10 Practice Recommendations in Adult Vaccination Administration.

    Science.gov (United States)

    Oldfield, Benjamin J; Stewart, Rosalyn W

    2016-02-01

    Although the provision of immunoprophylaxis to children has become routine in the practice of pediatric preventive care, the same is not true in adult primary care. Contributing to this problem is a lack of knowledge among providers of adult preventive care. This review aimed to bolster providers' understanding of adult vaccinations by highlighting changes in vaccination recommendations and addressing common knowledge gaps. This is not a comprehensive list of vaccination recommendations, but rather the "top 10" common misconceptions, advancements, and updates we have found in our reading of the vaccination literature and in our own experience in a training institution. PMID:26840962

  10. On the dynamics of the three-piece-freight truck

    DEFF Research Database (Denmark)

    Xia, Fujie; True, Hans

    2003-01-01

    Although the three-piece-freight truck is a simple design its mathematical model is very complicated. The model is definitely a nonlinear dynamical system, where the nonlinearities arise from the nonlinear kinematic and dynamical contact relations between wheels and rails, the suspensions and the...... nonlinear dry friction damping with hysteresis and stick-slip action. The bolster moves both vertically and laterally relative to the truck frames, so the friction forces on the contact surfaces of the wedges must be treated as two-dimensional vectors, and the same holds for the dry friction on the surfaces...

  11. Contributed Review: Quartz force sensing probes for micro-applications

    Science.gov (United States)

    Abrahamians, Jean-Ochin; Pham Van, Laurent; Régnier, Stéphane

    2016-07-01

    As self-sensing and self-exciting probes, quartz sensors present many advantages over silicon cantilevers for microscopy, micro-robotics, and other micro-applications. Their development and use is further bolstered by the fact that they can be manufactured from common quartz components. This paper therefore reviews applications of the increasingly popular quartz tuning fork probes as force sensors in the literature and examines the options for higher-frequency quartz probes using the other available types of flexional, thickness-shear or length-extensional resonators.

  12. Comptia Network+ review guide exam N10-006

    CERN Document Server

    Ferguson, Bill

    2015-01-01

    Be prepared for the Network+ exam CompTIA Network+ Review Guide is your ideal study companion for preparing for the CompTIA Network+ exam (N10-006). This concise review is the perfect companion to the CompTIA Network+ Study Guide and the CompTIA Network+ Deluxe Study Guide, with full exam coverage organized by objective for quick review and reinforcement of key topics. Each of the book's five parts is devoted to a specific domain area of the exam, providing a focused review to bolster areas of weak understanding. You get access to the Sybex test engine, which includes two bonus practice tests

  13. HEMATOMA AURIKULA

    Directory of Open Access Journals (Sweden)

    Sari Indah

    2014-12-01

    Full Text Available Hematoma aurikula merupakan sekuele yang terjadi akibat trauma langsung pada daun telingayang menyebabkan penimbunan darah dalam ruang antara perikondrium dan kartilago yang biasanyaditemukan pada pegulat atau petinju. Keterlambatan diagnosis serta penanganan dapat menimbulkankomplikasi dimana salah satunya adalah telinga kembang kol atau cauliflower ear. Penatalaksanaanhematoma aurikula cukup bervariasi, namun tujuan utama pengobatan tersebut adalah mengevakuasidarah subperikondrial, mencegah kekambuhan, dan mencegah terjadinya infeksi. Dilaporkan satukasus hematoma aurikula pada seorang laki-laki dewasa berusia 68 tahun di Rumah Sakit UmumPusat ( RSUP  Sanglah-Denpasar yang telah dilakukan penanganan aspirasi serta bebat tekanmenggunakan teknik bolster yang memberikan hasil yang baik.

  14. Towards high performing hospital enterprise systems: an empirical and literature based design framework

    Science.gov (United States)

    dos Santos Fradinho, Jorge Miguel

    2014-05-01

    Our understanding of enterprise systems (ES) is gradually evolving towards a sense of design which leverages multidisciplinary bodies of knowledge that may bolster hybrid research designs and together further the characterisation of ES operation and performance. This article aims to contribute towards ES design theory with its hospital enterprise systems design (HESD) framework, which reflects a rich multidisciplinary literature and two in-depth hospital empirical cases from the US and UK. In doing so it leverages systems thinking principles and traditionally disparate bodies of knowledge to bolster the theoretical evolution and foundation of ES. A total of seven core ES design elements are identified and characterised with 24 main categories and 53 subcategories. In addition, it builds on recent work which suggests that hospital enterprises are comprised of multiple internal ES configurations which may generate different levels of performance. Multiple sources of evidence were collected including electronic medical records, 54 recorded interviews, observation, and internal documents. Both in-depth cases compare and contrast higher and lower performing ES configurations. Following literal replication across in-depth cases, this article concludes that hospital performance can be improved through an enriched understanding of hospital ES design.

  15. Multidisciplinary design optimization of vehicle instrument panel based on multi-objective genetic algorithm

    Science.gov (United States)

    Wang, Ping; Wu, Guangqiang

    2013-03-01

    Typical multidisciplinary design optimization(MDO) has gradually been proposed to balance performances of lightweight, noise, vibration and harshness(NVH) and safety for instrument panel(IP) structure in the automotive development. Nevertheless, plastic constitutive relation of Polypropylene(PP) under different strain rates, has not been taken into consideration in current reliability-based and collaborative IP MDO design. In this paper, based on tensile test under different strain rates, the constitutive relation of Polypropylene material is studied. Impact simulation tests for head and knee bolster are carried out to meet the regulation of FMVSS 201 and FMVSS 208, respectively. NVH analysis is performed to obtain mainly the natural frequencies and corresponding mode shapes, while the crashworthiness analysis is employed to examine the crash behavior of IP structure. With the consideration of lightweight, NVH, head and knee bolster impact performance, design of experiment(DOE), response surface model(RSM), and collaborative optimization(CO) are applied to realize the determined and reliability-based optimizations, respectively. Furthermore, based on multi-objective genetic algorithm(MOGA), the optimal Pareto sets are completed to solve the multi-objective optimization(MOO) problem. The proposed research ensures the smoothness of Pareto set, enhances the ability of engineers to make a comprehensive decision about multi-objectives and choose the optimal design, and improves the quality and efficiency of MDO.

  16. Development of a tilting system for electric multiple unit to speed up on conventional lines

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Sung Il; Kim, Nam Po; Lee, Soo Gil; Kim, Seok Won [Korea Railroad Research Institute, Uiwang (Korea, Republic of)

    2008-11-15

    An advanced tilting system for KTT (Korean Tilting Train) was developed and a performance test of the system has been completed. KTT has been constructed to speed up and promise a significant enhancement in service quality on a conventional line. KTT is an electric multiple unit composed of 6 cars running at the design speed of 200 km/h. The tilting system is the core technology of KTT and combined with the conventional bogie system. It has a self-steering mechanism and a swing link. The self-steering mechanism of Z-bar type is free to rotate on the curve and stable to run on a straight line. The swing link mechanism of the bolster enables the carbody to tilt up to 8 .deg.. A tilting control system detects a curve with sensors and commands the electro-mechanical actuators to move the bolster through the computer network system. GPS collaborates with the tilting system to perceive the curve previously and enables gradual tilting so as not to violate passenger comfort. The performance of the tilting system has been verified by a trial test running of KTT on a commercial conventional line. The tilting system is ready for commercial use

  17. Development of a tilting system for electric multiple unit to speed up on conventional lines

    International Nuclear Information System (INIS)

    An advanced tilting system for KTT (Korean Tilting Train) was developed and a performance test of the system has been completed. KTT has been constructed to speed up and promise a significant enhancement in service quality on a conventional line. KTT is an electric multiple unit composed of 6 cars running at the design speed of 200 km/h. The tilting system is the core technology of KTT and combined with the conventional bogie system. It has a self-steering mechanism and a swing link. The self-steering mechanism of Z-bar type is free to rotate on the curve and stable to run on a straight line. The swing link mechanism of the bolster enables the carbody to tilt up to 8 .deg.. A tilting control system detects a curve with sensors and commands the electro-mechanical actuators to move the bolster through the computer network system. GPS collaborates with the tilting system to perceive the curve previously and enables gradual tilting so as not to violate passenger comfort. The performance of the tilting system has been verified by a trial test running of KTT on a commercial conventional line. The tilting system is ready for commercial use

  18. Motivic multiple zeta values and superstring amplitudes

    International Nuclear Information System (INIS)

    The structure of tree-level open and closed superstring amplitudes is analyzed. For the open superstring amplitude we find a striking and elegant form, which allows one to disentangle its α′-expansion into several contributions accounting for different classes of multiple zeta values. This form is bolstered by the decomposition of motivic multiple zeta values, i.e. the latter encapsulate the α′-expansion of the superstring amplitude. Moreover, a morphism induced by the coproduct maps the α′-expansion onto a non-commutative Hopf algebra. This map represents a generalization of the symbol of a transcendental function. In terms of elements of this Hopf algebra the α′-expansion assumes a very simple and symmetric form, which carries all the relevant information. Equipped with these results we can also cast the closed superstring amplitude into a very elegant form. (paper)

  19. Climate change and the insurance industry. The cost of increased risk and the impetus for action

    International Nuclear Information System (INIS)

    A convincing economic argument for taking action to prevent or ameliorate climate change has not developed because of both uncertainty about the degree of change and its timing. Recent costly weather-related catastrophes with consequent negative impacts on the insurance industry has made the insurance industry a potential advocate for slowing what has been identified as a causal factor in climate change: emissions of greenhouse gases. However, rising costs of claims, without a longer-term trend of such catastrophic losses, will make it difficult to present a strong case for taking costly economic action. Using the Black Scholes Option Pricing Model, it is shown that increasing levels of climate variability as embedded in the anticipated variability of damage to insured assets will have an immediate economic cost that could serve to bolster the argument for more immediate action. That cost is shown to be economically justified higher insurance premiums

  20. Housing as a Social Determinant of Health: Exploring the Relationship between Rent Burden and Risk Behaviors for Single Room Occupancy Building Residents.

    Science.gov (United States)

    Bowen, Elizabeth A; Mitchell, Christopher G

    2016-01-01

    A growing body of health determinants research recognizes that housing and health are intimately linked. This study explores the relationship between rent burden (the ratio of rent to income) and health risk behaviors among a sample of single room occupancy (SRO) building residents. Cross-sectional data were gathered from a sample of 162 residents living in privately owned, for-profit SROs in Chicago. Findings indicated that participants who had full rental subsidies and thus were designated in a no-rent-burden category were more likely to engage in risk behaviors including illicit drug use, having multiple sexual partners, and having sex without a condom, in comparison to participants with moderate or high-rent burdens. These findings suggest that interventions to increase housing stability and affordability and bolster reliable income sources (in addition to rental subsidies) may be key in reducing risk behaviors and improving health for vulnerably housed populations such as SRO residents. PMID:27167535

  1. Modeling of nanotoxicity molecular interactions of nanomaterials with bionanomachines

    CERN Document Server

    Zhou, Ruhong

    2015-01-01

    This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines. It lays out the fundamentals of nanotoxicity modeling for an array of nanomaterial systems, ranging from carbon-based nanoparticles to noble metals, metal oxides, and quantum dots. The author illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling approaches can be applied to bolster our understanding of many important aspects of this critical nanotoxicity issue. Each chapter is organized by types of nanomaterials for practicality, making this an ideal book for senior undergraduate students, graduate students, and researchers in nanotechnology, chemistry, physics, molecular biology, and computer science. It is also of interest to academic and industry professionals who work on nanodrug delivery and related biomedical applications, and aids readers in their biocompatibility assessment efforts in the coming age of nanotechnology...

  2. Shifting Liberal and Conservative Attitudes Using Moral Foundations Theory

    Science.gov (United States)

    Day, Martin V.; Fiske, Susan T.; Downing, Emily L.; Trail, Thomas E.

    2016-01-01

    People’s social and political opinions are grounded in their moral concerns about right and wrong. We examine whether five moral foundations—harm, fairness, ingroup, authority, and purity—can influence political attitudes of liberals and conservatives across a variety of issues. Framing issues using moral foundations may change political attitudes in at least two possible ways: 1. Entrenching: relevant moral foundations will strengthen existing political attitudes when framing pro-attitudinal issues (e.g., conservatives exposed to a free-market economic stance). 2. Persuasion: mere presence of relevant moral foundations may also alter political attitudes in counter-attitudinal directions (e.g., conservatives exposed to an economic regulation stance). Studies 1 and 2 support the entrenching hypothesis. Relevant moral foundation-based frames bolstered political attitudes for conservatives (Study 1) and liberals (Study 2). Only Study 2 partially supports the persuasion hypothesis. Conservative-relevant moral frames of liberal issues increased conservatives’ liberal attitudes. PMID:25286912

  3. Religion and health connection: a study of African American, Protestant Christians.

    Science.gov (United States)

    Gonnerman, Melvin E; Lutz, Gene M; Yehieli, Michele; Meisinger, Bruce K

    2008-02-01

    The roles religious and health promoting behaviors may play in bolstering positive physical and emotional health were assessed using structured, face-to-face interviews conducted using a non-random community sample of 105 adult African American, Protestant Christians in a small city in a rural state in the Midwest. The interview measured health promotion, health locus of control beliefs, emotional health, physical health, religious practices, and demographics. Health promotion, church attendance, or both were related to decreased prevalence of loneliness, depression, trouble sleeping, and family problems. More than 80% of those interviewed ascribed healing power to God and prayer. There was an apparent lack of connection between respondents' attitudes about faith and healing and their actual experiences. PMID:18263995

  4. Experience Economy, Innovation and Traditional Industries

    DEFF Research Database (Denmark)

    Arthur, Isaac Kwamena

    This thesis investigates the role experience-based innovations can play in rural Denmark. The objective is to understand how food enterprises in Danish rural areas are reinventing themselves as viable units in the contemporary world by exploiting the potentials of the experience economy, and in...... practical terms, advise on its potential to enhance the competitiveness for food enterprises and implications for local development. This has been necessitated by the increasing competitions in the contemporary global business/economic environment and the need for strategic measures to bolster the...... competitive prospects of traditional rural enterprises and socio-economic vibrancy of rural areas. The guiding research questions to address the thesis’ objective are what characterises the experience-based innovations of food enterprises; what are the mechanisms that shape the experience-based innovations...

  5. Analysis of Batik Value Chain in Ethnic Minority Areas--A Case Study of Danzhai County in Guizhou Province

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Based on value chain analysis method,we surveyed and interviewed interest groups of batik industry in Danzhai County.From raw material production,product processing,marketing,organization and management,we discussed the supply chain of batik products in ethnic minority areas,and analyzed favorable factors of batik industry development and obstacles to interest groups developing batik industry.Finally,we put forward corresponding policy suggestions,including strengthening farmers’ ability in batik production section,enhancing capability construction of batik cooperatives and associations,increasing cultural value added of batik products,bolster policy and financial support of government departments,and promoting establishment of cooperative mechanism for handicrafts.

  6. The Concept of Alliance as an Image and Positioning Instrument for Institutions of Higher Learning

    Directory of Open Access Journals (Sweden)

    Víctor Manuel Alcántar Enríquez

    2004-05-01

    Full Text Available The present work provides a foundation for the concept of alliance which includes the ability of this to foster the university’s societal position as based on public perception of the institution. Accordingly, the work briefly addresses the development of the university’s collaboration with the productive sector, and emphasizes the need for institutions of higher learning to consider as well, those social sectors (including the government outside the realm of industry or technological expansion. The study concludes by affirming that alliance can become an effective instrument for promoting the university. It is therefore necessary to research the social perception of the university as a means of bolstering its relevance.

  7. Stabilization of switched nonlinear systems with unstable modes

    CERN Document Server

    Yang, Hao; Cocquempot, Vincent

    2014-01-01

    This book provides its reader with a good understanding of the stabilization of switched nonlinear systems (SNS), systems that are of practical use in diverse situations: design of fault-tolerant systems in space- and aircraft; traffic control; and heat propagation control of semiconductor power chips. The practical background is emphasized throughout the book; interesting practical examples frequently illustrate the theoretical results with aircraft and spacecraft given particular prominence. Stabilization of Switched Nonlinear Systems with Unstable Modes treats several different subclasses of SNS according to the characteristics of the individual system (time-varying and distributed parameters, for example), the state composition of individual modes and the degree and distribution of instability in its various modes. Achievement and maintenance of stability across the system as a whole is bolstered by trading off between individual modes which may be either stable or unstable, or by exploiting areas of part...

  8. Republic of Moldova: between the Eropean Union and Commonwealth of Independent States

    Directory of Open Access Journals (Sweden)

    Yuri Josanu

    2012-08-01

    Full Text Available Moldova is the second smallest and the most densely populated of the NIS. It began the arduous task of building a democratic nation and market-based economy as it faced ethnic conflicts and the social hardships accompanying economic and political transformation. The country has pushed ahead with economic policy reform as a model of change among NIS countries. Moldova is also considered one of the top NIS performers in democratic development. Internal political tensions over the pace of reforms have delayed progress in land privatization and fiscal improvement. Underlying all of these issues is the festering problem of Transdniester where ethnic Russians, bolstered by the presence of Russian troops, thus denying Moldova control over significant industrial assets.

  9. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    International Nuclear Information System (INIS)

    Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies

  10. Improving HCAHPS Scores with Advances in Digital Radiography.

    Science.gov (United States)

    Matthews, Marianne; Cretella, Gregg; Nicholas, William

    2016-01-01

    The imaging department can be instrumental in contributing to a healthcare facility's ability to succeed in this new era of competition. Advances in DR technology can improve patient perceptions in the imaging department by improving efficiencies and outcomes which, in turn, can ultimately bolster overall HCAHPS scores. Specific areas for improved scores by utilization of DR include nurse communication, doctor communication, pain management, and communication about medication. Value based purchasing brought with it a mandate for hospitals to track key metrics, which requires an investment in time, tools, and human resources. However, this mandate also presents hospitals and imaging departments, with an opportunity to leverage those very metrics to better market their facilities. PMID:26939298

  11. Lesbian, Gay, and Bisexual Identity as a Moderator of Relationship Functioning After Sexual Assault.

    Science.gov (United States)

    Gemberling, Tess M; Cramer, Robert J; Miller, Rowland S; Stroud, Caroline H; Noland, Ramona M; Graham, James

    2015-12-01

    Sexual assault is unfortunately common, especially among lesbian, gay, and bisexual (LGB) individuals. Yet, the associations of such victimization have not yet been extensively established in the areas of sexual identity and romantic relationship functioning. Accordingly, the present study examined the associations between lifetime sexual assault, LGB identity, and romantic relationship functioning in a sample of 336 LGB individuals. A history of sexual assault was associated with attachment anxiety and several sexual identity components (i.e., higher levels of acceptance concerns, identity uncertainty, internalized homonegativity, and identity superiority). Furthermore, an association of sexual assault and attachment avoidance was moderated by internalized homonegativity. Finally, a more secure LGB identity was associated with healthier romantic relationship functioning. Collectively, these findings are applicable to services for LGB sexual assault victims, suggesting the incorporation of treatment that bolsters LGB identity and couple functioning. Limitations and future directions are discussed. PMID:25516131

  12. Moving water to South America as observed from space

    Science.gov (United States)

    Liu, W. Timothy; Xie, Xiaosu

    2006-01-01

    The approximate balance of the mass change rate measured by the Gravity Recovery and Climate Experiment (GRACE) with the moisture influx across the entire coastline less climatological river discharge for South America (SA), in agreement with the conservation principle, bolsters not only the credibility of the spacebased measurements, but supports the characterization of ocean's influence on the annual variation of continental water balance. The moisture transport integrated over the depth of the atmosphere is estimated using measurements by QuikSCAT and Special Sensor Microwave/Imager. The large-scale geographic patterns of precipitation from the Tropical Rain Measuring Mission (TRMM) and the mass change rate were found to follow similar annual changes over South America.

  13. Platelets in Lung Biology

    Science.gov (United States)

    Weyrich, Andrew S.; Zimmerman, Guy A.

    2013-01-01

    Platelets and the lungs have an intimate relationship. Platelets are anucleate mammalian blood cells that continuously circulate through pulmonary vessels and that have major effector activities in hemostasis and inflammation. The lungs are reservoirs for megakaryocytes, the requisite precursor cell in thrombopoiesis, which is the intricate process by which platelets are generated. Platelets contribute to basal barrier integrity of the alveolar capillaries, which selectively restricts the transfer of water, proteins, and red blood cells out of the vessels. Platelets also contribute to pulmonary vascular repair. Although platelets bolster hemostatic and inflammatory defense of the healthy lung, experimental evidence and clinical evidence indicate that these blood cells are effectors of injury in a variety of pulmonary disorders and syndromes. Newly discovered biological capacities of platelets are being explored in the context of lung defense, disease, and remodeling. PMID:23043249

  14. FIPSER: Performance Study of a Readout Concept With Few Digitization Levels for Fast Signals

    CERN Document Server

    Limyansky, Brent; Cressler, John D; Otte, Adam Nepomuk; Taboada, Ignacio; Ulusoy, Cagri

    2016-01-01

    We discuss the performance of a readout system, Fixed Pulse Shape Efficient Readout (FIPSER), to digitize signals from detectors with a fixed pulse shape. In this study we are mainly interested in the readout of fast photon detectors like photomultipliers or Silicon photomultipliers. But the concept can be equally applied to the digitization of other detector signals. FIPSER is based on the flash analog to digital converter (FADC) concept, but has the potential to lower costs and power consumption by using an order of magnitude fewer discrete voltage levels. Performance is bolstered by combining the discretized signal with the knowledge of the underlying pulse shape. Simulated FIPSER data was reconstructed with two independent methods. One using a maximum likelihood method and the other using a modified chisquared test. Both methods show that utilizing 12 discrete voltage levels with a sampling rate of 4 samples per full width half maximum (FWHM) of the pulse achieves an amplitude resolution that is better th...

  15. The whisper of death: psychotherapy with a dying Vietnam veteran.

    Science.gov (United States)

    Caffrey, T A

    2000-01-01

    Psychotherapy with a dying Vietnam veteran is described. In spite of a severe heart condition and HIV-positive diagnosis, the outspoken and provocative patient reverts to heroin and cocaine use early in the treatment. This causes a heart attack and interruption of treatment. The therapist maintains empathy, a solid bond is forged, and the patient returns, but under constrained circumstances. A turning point is reached, both in the treatment and in this final phase of the patient's life, with major life improvement ensuing. At death the patient leaves word to thank the therapist. This case exemplifies how the approach of death lends urgency to positive forces appropriate to life's final developmental stage, and how end-of-life therapy bolsters those forces. PMID:11109136

  16. Morphological communication: exploiting coupled dynamics in a complex mechanical structure to achieve locomotion

    Science.gov (United States)

    Rieffel, John A.; Valero-Cuevas, Francisco J.; Lipson, Hod

    2010-01-01

    Traditional engineering approaches strive to avoid, or actively suppress, nonlinear dynamic coupling among components. Biological systems, in contrast, are often rife with these dynamics. Could there be, in some cases, a benefit to high degrees of dynamical coupling? Here we present a distributed robotic control scheme inspired by the biological phenomenon of tensegrity-based mechanotransduction. This emergence of morphology-as-information-conduit or ‘morphological communication’, enabled by time-sensitive spiking neural networks, presents a new paradigm for the decentralized control of large, coupled, modular systems. These results significantly bolster, both in magnitude and in form, the idea of morphological computation in robotic control. Furthermore, they lend further credence to ideas of embodied anatomical computation in biological systems, on scales ranging from cellular structures up to the tendinous networks of the human hand. PMID:19776146

  17. Organizational Maturity in Competitive Intelligence – The Case of a Brazilian Financial Institution

    Directory of Open Access Journals (Sweden)

    Leonel Cezar Rodrigues

    2014-04-01

    Full Text Available This study aims at characterizing and identifying the degree of maturity in Competitive Intelligence (CI of a financial organization from a developing country, abyding by a maturity model in the literature. To do this research, the chosen method was the case study. Data were collected among 4 distinct áreas of the organization: Marketing, Physical Security; International Relations; and Risk management.  Main results indicate that two áreas show maturity in CI, level 1 – Informal. The othe two show degree of maturity in CI, level 2 – Formal. Conclusions of the study support coherence of criteria and elements that bolster the logic of the selected model and the decentralized structure of CI in the studied organization, showing, in an yet intuitive way, to hold an advanced CI operating model.

  18. [Possibilities of inclusion of the partner in deliveries in public institutions].

    Science.gov (United States)

    Brüggemann, Odaléa Maria; Ebsen, Erika Simas; Ebele, Romana Raquel; Batista, Bruna Daniela

    2016-08-01

    Qualitative research, with an exploratory and descriptive approach, was conducted between September 2011 and February 2012, aimed at revealing the possibility of inclusion of the partner in deliveries in institutions that currently restrict their presence. Twelve nurses responsible for obstetric centers and five technical directors of health institutions of Santa Catarina, who did not allow or infrequently allowed the presence of the partner during delivery, were interviewed. Data were analyzed using Bardin Content Analysis, with the support of ATLAS.ti software. The possibilities of including the partner are permitted in three categories: I - Labor pain process; II - Receptiveness of professionals to the partner; and III - Empowerment of patients. Although some institutions limit the presence of the partner, they describe aspects that favor their inclusion. From the results presented, it is suggested that these enabling elements could be bolstered with management strategies, ongoing learning and intersectoral actions. PMID:27557028

  19. Immunotherapy: Shifting the Balance of Cell-Mediated Immunity and Suppression in Human Prostate Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Tucker, Jo A.; Jochems, Caroline [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Gulley, James L. [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Schlom, Jeffrey, E-mail: js141c@nih.gov; Tsang, Kwong Y. [Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States)

    2012-12-11

    Active immunotherapy is dependent on the ability of the immune system to recognize and respond to tumors. Despite overwhelming evidence to support a cell-mediated immune response to prostate cancer, it is insufficient to eradicate the disease. This is likely due to a high level of suppression at the tumor site from a variety of sources, including immunosuppressive cells. Immune cells entering the tumor microenvironment may be inhibited directly by the tumor, stromal cells or other immune cells that have been induced to adopt a suppressive phenotype. The resurgence of interest in immunotherapy following the approval of sipuleucel-T and ipilimumab by the Food and Drug Administration has brought about new strategies for overcoming tumor-mediated suppression and bolstering anti-tumor responses. Improved understanding of the immune response to prostate cancer can lead to new combination therapies, such as the use of vaccine with small molecule and checkpoint inhibitors or other immunotherapies.

  20. Costs of global climate protection

    International Nuclear Information System (INIS)

    This paper discusses the cost implications of the air pollution abatement recommendations contained in a recently published IPSEP (International Project for Sustainable Energy Paths) study on the feasibility of the abatement of carbon dioxide emissions deemed significantly responsible for the greenhouse effect and its associated negative impacts on this planet's climatic equilibrium. The air pollution abatement strategies are to be enforced in five highly industrialized European countries - Germany, France, Great Britain, Italy and Holland. The study's overall results indicate the feasibility of 50% reductions in carbon dioxide emissions within the next 30 years even with a more than doubling of GNP's and a contemporaneous phase-out of nuclear power production, and all this taking place in a cost effective way and with increased employment. In addition, IPSEP's report states that the implementation of effective program management strategies would bolster Western Europe's competitiveness on a global scale

  1. Stakeholders in Action

    DEFF Research Database (Denmark)

    of stakeholders and stakeholder roles, which may pave the way for dedicated management and communication strategies to enhance and bolster relationships. This volume follows in the footsteps of the many researchers who have studied and explored the field; however, as opposed to much current...... literature, which often takes a primarily theoretical approach to the study of stakeholders and stakeholder management, the chapters in this book are first and foremost focused on the practical aspects of the field. Thus, through seven separate case studies, the book discusses how stakeholders are...... constructed implicitly and explicitly in corporate and institutional texts, investigating the possible consequences of these constructions for the communication and engagement between stakeholders and organisations....

  2. Region III involvement in quality control and quality assurance of radon testing methods

    International Nuclear Information System (INIS)

    Region III has set a goal of increasing the testing for radon by our residents. One approach to this goal, is to bolster the public's confidence in the testing laboratories. We believe that this can be done most effectively by assuring the quality of the measurements available to the public. All Proficient Laboratories and Pennsylvania Certified Laboratories have submitted a quality assurance (QA) program. A QA audit checklist has been developed which will be finalized and made available to the states in our Region. This paper deals with inspection, verification, and documentation of the various laboratories and their compliance with prudent measuring protocols and addresses the following items: Organization and responsibilities; Sampling procedures; Detector chain of custody; Measurement procedures, quality control checks; State certification and RMP; Data resection, validation, and reporting; Quality assurance reports to management; Interview and discussion of QA audit with responsible officer

  3. Normative Ethics and Sport: A Moral Manifesto

    Directory of Open Access Journals (Sweden)

    Kosiewicz Jerzy

    2014-06-01

    Full Text Available This article constitutes a strictly cognitive and completely non-ideological moral (or rather, amoral manifesto that makes no value judgments. The article concerns relationships that, according to sport enthusiasts with varying levels of competence, occur between sport and normative ethics. The author of this article supports a standpoint he terms ethical negationism that rejects the need for moral rules to externally support and bolster the rules of sport competition. The author assumes that the rules of sport play and competition are, and should be, completely amoral and independent from ethics. While this article is a fully autonomous ethical manifesto, it also constitutes an introduction to other articles in this issue of the journal arguing that sport competition takes place beyond the scope of moral good and evil.

  4. Potential of Neural Stem Cells for the Treatment of Brain Tumors

    Directory of Open Access Journals (Sweden)

    P. Taupin

    2008-01-01

    Full Text Available Neural stem cells (NSCs are self-renewing multipotent cells that generate the main phenotypes of the nervous system, neurons, astrocytes and oligodendrocytes. As such they hold the promise to treat a broad range of neurological diseases and injuries. Neural progenitor and stem cells have been isolated and characterized in vitro, from adult, fetal and post-mortem tissues, providing sources of material for cellular therapy. However, NSCs are still elusive cells and remain to be unequivocally identified and characterized, limiting their potential use for therapy. Neural progenitor and stem cells, isolated and cultured in vitro, can be genetically modified and when transplanted migrate to tumor sites in the brain. These intrinsic properties of neural progenitor and stem cells provide tremendous potential to bolster the translation of NSC research to therapy. It is proposed to combine gene therapy and cellular therapy to treat brain cancers. Hence, neural progenitor and stem cells provide new opportunities for the treatment of brain cancers.

  5. Historical time in the age of big data: Cultural psychology, historical change, and the Google Books Ngram Viewer.

    Science.gov (United States)

    Pettit, Michael

    2016-05-01

    Launched in 2010, the Google Books Ngram Viewer offers a novel means of tracing cultural change over time. This digital tool offers exciting possibilities for cultural psychology by rendering questions about variation across historical time more quantitative. Psychologists have begun to use the viewer to bolster theories about a historical shift in the United States from a more collectivist to individualist form of selfhood and society. I raise 4 methodological cautions about the Ngram Viewer's use among psychologists: (a) the extent to which print culture can be taken to represent culture as a whole, (b) the difference between viewing the past in terms of trends versus events, (c) assumptions about the stability of a word's meaning over time, and (d) inconsistencies in the scales and ranges used to measure change over time. The aim is to foster discussion about the standards of evidence needed for incorporating historical big data into empirical research. (PsycINFO Database Record PMID:27100927

  6. Programming iOS 4 Fundamentals of iPhone, iPad, and iPod touch Development

    CERN Document Server

    Neuburg, Matt

    2011-01-01

    Get a solid grounding in all the fundamentals of Cocoa Touch, and avoid problems during iPhone and iPad app development. With Programming iOS 4, you'll dig into Cocoa and learn how to work effectively with Objective-C and Xcode. This book covers iOS 4 in a rigorous, orderly fashion-ideal whether you're approaching iOS for the first time or need a reference to bolster existing skills. Learn Objective-C language details and object-oriented programming conceptsUnderstand the anatomy of an Xcode project and all the stages of its lifecycleGrasp key Cocoa concepts such as relationships between clas

  7. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Gholamhosein Tavacoly

    2011-09-01

    Full Text Available   Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist , then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.   In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  8. Craig and Kalam Cosmological Argument

    Directory of Open Access Journals (Sweden)

    Tavacoli, Gh

    2011-01-01

    Full Text Available Among different arguments for the existence of God the Kalam cosmological argument is a very famous one which is elaborated by Professor William lane Craig. Craig claims that the universe began to exist, then he continues to say: everything that begins to exist has a cause and therefore the universe has a cause. But how do we know that the universe began to exist? This premise forms the most important part of Craig’s contention, and he bolsters it by four arguments, the first two are driven from philosophy and the other two, which he prefers to name them “confirmations from sciences” are driven from sciences; the first one evokes to big bang theory and the seconds to the second principle of thermodynamic which are respectively adopted from cosmology and physics.In this essay we are going to survey Craig’s arguments and estimate their value and weight.

  9. Determinants of Scale Efficiency in the Brazilian Third-Party Logistics Industry from 2001 to 2009

    Directory of Open Access Journals (Sweden)

    Peter F. Wanke

    2012-01-01

    Full Text Available This article investigates the Brazilian third-party logistics (3PL sector which, increasingly competitive, offers clients a wide variety of services/information technologies in the quest to bolster efficiency. The main research objective is to determine which variables significantly impact 3PLs scale efficiency by applying two-stage DEA (Data Envelopment Analysis. Based on an unbalanced panel model, data from the annual study published by Revista Tecnologística (years 2001–2009 were analyzed. Results corroborate evidence in the literature that coordination mechanisms in the supply chain, supported by the availability of real time information and inventory synchronization, favor a more rational allocation of resources (inputs to client demands (outputs.

  10. The Critical Role of Clerks in the Patient-Centered Medical Home.

    Science.gov (United States)

    Solimeo, Samantha L; Stewart, Greg L; Rosenthal, Gary E

    2016-07-01

    Research evaluating the effectiveness, function, and implementation of patient-centered medical homes (PCMHs) has found major socioprofessional transformations and contributions of primary care physicians and, to a lesser degree, nurses. Our longitudinal ethnographic research with teams implementing PCMH in Veterans Health Administration (VHA) primary care identifies the important but largely underutilized contributions of clerks to PCMH outcomes. Although the relationship of high-performing clerical staff to patient satisfaction is widely acknowledged, PCMH can be further enhanced by enabling clerks to use administrative tasks as conduits for investing in long-term personalized relationships with patients that foster trust in the PCMH and the broader health care organization. Such relationships are engendered through the care-coordination activities clerks perform, which may be bolstered by organizational investment in clerks as skilled health care team members. PMID:27401428

  11. First detection of Agrilus planipennis in Connecticut made by monitoring Cerceris fumipennis (Crabronidae colonies

    Directory of Open Access Journals (Sweden)

    Claire Rutledge

    2013-04-01

    Full Text Available Smoky winged beetle bandits, Cerceris fumipennis Say, digger wasps in the family Hymenoptera: Crabronidae: Cercerini, provision their underground nests with adult metallic wood-boring beetles (Coleoptera: Buprestidae. Researchers, as well as engaged community volunteers, in several states have monitored female wasps returning to their nests as a means to detect invasive buprestid species. In this paper, we report the first detection of emerald ash borer (Agrilus planipennis Fairemore, an invasive beetle responsible for killing millions of ash trees in North America, in Connecticut by C. fumipennis and discuss its relationship to A. planipennis survey efforts by other modalities in the state. We also report detections of A. planipennis by C. fumipennis in Illinois, New York and Ontario; all of which were made after it was known the beetle was in the area. These findings support the use of C. fumipennis as a biomonitoring tool and bolster the use of engaged volunteers.

  12. Clarifying the link between childhood abuse history and psychopathic traits in adult criminal offenders.

    Science.gov (United States)

    Dargis, Monika; Newman, Joseph; Koenigs, Michael

    2016-07-01

    Childhood abuse is a risk factor for the development of externalizing characteristics and disorders, including antisocial personality disorder and psychopathy. However, the precise relationships between particular types of childhood maltreatment and subsequent antisocial and psychopathic traits remain unclear. Using a large sample of incarcerated adult male criminal offenders (n = 183), the current study confirmed that severity of overall childhood maltreatment was linked to severity of both psychopathy and antisocial personality disorder in adulthood. Moreover, this relationship was particularly strong for physical abuse and the antisocial facet of psychopathy. Sexual abuse history was uniquely related to juvenile conduct disorder severity, rather than adult psychopathy or antisocial behaviors. Additionally, there was a significantly stronger relationship between childhood maltreatment and juvenile conduct disorder than between childhood maltreatment and ASPD or psychopathy. These findings bolster and clarify the link between childhood maltreatment and antisocial behavior later in life. (PsycINFO Database Record PMID:26389621

  13. The Relationship Between Psychopathology and a Hierarchical Model of Normal Personality Traits: Evidence From a Psychiatric Patient Sample.

    Science.gov (United States)

    Uliaszek, Amanda A; Al-Dajani, Nadia; Bagby, R Michael

    2015-12-01

    Shifts in the conceptualization of psychopathology have favored a dimensional approach, with the five-factor model (FFM) playing a prominent role in this research. However, reservations about the utility of the FFM in differentiating disorders have risen. In the current investigation, a "bottom-up" analytical method was used to ascertain the hierarchical structure of personality, with investigation of the specificity of the traits in categorizing diagnostic categories across an expanded array of psychiatric disorders. Following earlier investigations, which used a hierarchical structural approach, this study presents new results relating to the differentiation of several forms of psychopathology not included in these earlier analyses--bipolar disorder, psychotic disorders, problem gambling, posttraumatic stress disorder, and somatoform disorders--across distinct levels of a personality hierarchy based on the FFM. These results bolster the argument for the use of FFM personality traits in characterizing and differentiating psychiatric diagnostic groups. PMID:25562540

  14. "To Bluff like a Man or Fold like a Girl?" – Gender Biased Deceptive Behavior in Online Poker

    Science.gov (United States)

    Palomäki, Jussi; Yan, Jeff; Modic, David; Laakasuo, Michael

    2016-01-01

    Evolutionary psychology suggests that men are more likely than women to deceive to bolster their status and influence. Also gender perception influences deceptive behavior, which is linked to pervasive gender stereotypes: women are typically viewed as weaker and more gullible than men. We assessed bluffing in an online experiment (N = 502), where participants made decisions to bluff or not in simulated poker tasks against opponents represented by avatars. Participants bluffed on average 6% more frequently at poker tables with female-only avatars than at tables with male-only or gender mixed avatars—a highly significant effect in games involving repeated decisions. Nonetheless, participants did not believe the avatar genders affected their decisions. Males bluffed 13% more frequently than females. Unlike most economic games employed exclusively in research contexts, online poker is played for money by tens of millions of people worldwide. Thus, gender effects in bluffing have significant monetary consequences for poker players. PMID:27383472

  15. Spacebased Observations of Oceanic Influence on the Annual Variation of South American Water Balance

    Science.gov (United States)

    Liu, W. Timothy; Xie, Xiaosu; Tang, Wenqing; Zlotnicki, Victor

    2006-01-01

    The mass change of South America (SA) continent measured by the Gravity Recovery and Climate Experiment (GRACE) imposes a constraint on the uncertainties in estimating the annual variation of rainfall measured by Tropical Rain Measuring Mission (TRMM) and ocean moisture influx derived from QuikSCAT data. The approximate balance of the mass change rate with the moisture influx less climatological river discharge, in agreement with the conservation principle, bolsters not only the credibility of the spacebased measurements, but supports the characterization of ocean's influence on the annual variation of continental water balance. The annual variation of rainfall is found to be in phase with the mass change rate in the Amazon and the La Plata basins, and the moisture advection across relevant segments of the Pacific and Atlantic coasts agrees with the annual cycle of rainfall in the two basins and the Andes mountains.

  16. Internationalizing nuclear safety: The pursuit of collective responsibility

    International Nuclear Information System (INIS)

    The future of nuclear energy could depend upon the international infrastructure established to ensure the creation of a strong and uniform safety culture. Deliberations during the 1990s, leading to the recently promulgated International Nuclear Safety Convention, held out the prospect of both bolstering nuclear safety and gaining public recognition of the need to address transboundary safety concerns head-on. Unfortunately, the Convention that emerged from the deliberations constitutes little more than another form of technical assistance. The basis for an alternative, and more substantial, Convention is presented--one that would be based on the establishment and evaluation of performance standards, the creation of a series of political firebreaks, and the encouragement of nuclear power plant designs that minimize the catastrophic offsite consequences of accidents

  17. Linking Europa's plume activity to tides, tectonics, and liquid water

    CERN Document Server

    Rhoden, Alyssa R; Roth, Lorenz; Retherford, Kurt

    2015-01-01

    Much of the geologic activity preserved on Europa's icy surface has been attributed to tidal deformation, mainly due to Europa's eccentric orbit. Although the surface is geologically young (30 - 80 Myr), there is little information as to whether tidally-driven surface processes are ongoing. However, a recent detection of water vapor near Europa's south pole suggests that it may be geologically active. Initial observations indicated that Europa's plume eruptions are time-variable and may be linked to its tidal cycle. Saturn's moon, Enceladus, which shares many similar traits with Europa, displays tidally-modulated plume eruptions, which bolstered this interpretation. However, additional observations of Europa at the same time in its orbit failed to yield a plume detection, casting doubt on the tidal control hypothesis. The purpose of this study is to analyze the timing of plume eruptions within the context of Europa's tidal cycle to determine whether such a link exists and examine the inferred similarities and...

  18. Revision of Immediate Post-Open Heart Surgery Education for Critical Care RNs.

    Science.gov (United States)

    Mowry, Marianne J; Gabel, Mollie A

    2015-11-01

    Responding to the complex nature of critical care is imperative, as extensive clinical judgment is required during those vital moments when patients are experiencing complications related to open heart surgery, post-vessel bypass, or valve replacement. Critical care registered nurses must rely on evidence-based foundational knowledge and skills particular to cardiovascular pathophysiology, hemodynamic monitoring, and medications. This article reports on the critical care educator's revision of the immediate post-open heart surgery curriculum. Mixed educational methods within the plan were foundational to develop clinicians for competent care of these complex patients (within the first 8 hours). The revision included experiential learning and learner centeredness to bolster the learner's confidence, reduce the time to competence, and, most important, ensure positive patient outcomes. Kirkpatrick's classic four-level model provided the framework for evaluation. Lessons learned were discussed following the program initiation. PMID:26509403

  19. Songs for funerals and intercession. A collection of polyphony for the confraternity of St Barbara at the Corbie Abbey, Amiens, Bibliothèque Centrale Louis Aragon, MS 162 D. Edited by Peter Woetmann Christoffersen. Volume 1

    DEFF Research Database (Denmark)

    Christoffersen, Peter Woetmann

    2015-01-01

    the ideas of a new age, fought with arguments as well as violence. A bold move to bolster its position was the demolition of the abbey’s old main church and starting the building of a vast new one in 1502. The founding of the confraternity and the ordering of the music manuscript in Paris were......MS Amiens 162 was made in Paris in 1502 in cooperation between a professional music copyist and the young monk Antoine de Caulaincourt. The MS contained simple polyphony for funerals and commemorative services, and it was to be used in a confraternity, Confrérie Ste Barbe, at the big Benedictine...... probably deliverate moves to ensure local support for the building project. The MS offers music whose sound may compare with contemporary art music in fullness and solemnity, but monks who were neither able to read modern mensural notation nor improvise simple polyphony could perform it. Their competence...

  20. Rechtspraak en totale oorlog

    Directory of Open Access Journals (Sweden)

    S. Faber

    2004-01-01

    Full Text Available

    J. Meihuizen, Noodzakelijk kwaad. De bestraffing van economische collaboratie in Nederland na de Tweede Wereldoorlog

    A successful failure?

    Melhuizen’s powerful dissertation focuses on one section of the Special Judicial Procedure: settling cases of economic collaboration, particularly the more serious ones. He also examines the Special Judicial Procedure as a whole. First of all with figures, which are less reliable than suggested as is argued in this contribution. Secondly, he used these figures to bolster up his conclusion that we have failed to punish economic collaboration. This is questionable, because the element of punishment was more important in those days than can be deducted from Melhuizen’s views.

  1. Moving From Digitalization to Digitization in Cardiovascular Care: Why Is it Important, and What Could it Mean for Patients and Providers?

    Science.gov (United States)

    Steinhubl, Steven R; Topol, Eric J

    2015-09-29

    So far, the digitization of health care is best exemplified by electronic medical records, which have been far from favorably or uniformly accepted. However, properly implemented digitization can enable better patient outcomes, improve convenience, potentially lower healthcare costs, and possibly lead to much greater physician satisfaction. Precision (also known as personalized or individualized) medicine is frequently discussed today, but, in reality, it is what physicians have attempted to do as best they could for millennia. But now we have new tools that can begin to give us a much more high-definition view of our patients; from affordable and rapid genetic testing to wearable sensors that track a wide range of important physiologic parameters continuously. Although seemingly counterintuitive, the digitization of health care can also markedly improve the physician-patient relationship, allowing more time for human interaction when care is bolstered by digital technologies that better individualize diagnostics and treatments. PMID:26403346

  2. Language exposure facilitates talker learning prior to language comprehension, even in adults.

    Science.gov (United States)

    Orena, Adriel John; Theodore, Rachel M; Polka, Linda

    2015-10-01

    Adults show a native language advantage for talker identification, which has been interpreted as evidence that phonological knowledge mediates talker learning. However, infants also show a native language benefit for talker discrimination, suggesting that sensitivity to linguistic structure due to systematic language exposure promotes talker learning, even in the absence of functional phonological knowledge or language comprehension. We tested this hypothesis by comparing two groups of English-monolingual adults on their ability to learn English and French voices. One group resided in Montréal with regular exposure to spoken French; the other resided in Storrs, Connecticut and did not have French exposure. Montréal residents showed faster learning and better retention for the French voices compared to their Storrs-residing peers. These findings demonstrate that systematic exposure to a foreign language bolsters talker learning in that language, expanding the gradient effect of language experience on talker learning to perceptual learning that precedes sentence comprehension. PMID:26113447

  3. Science and Technology Review January/February 2011

    International Nuclear Information System (INIS)

    This month's issue has the following articles: (1) World's Most Intense X-Ray Laser Focuses on Livermore Science - Commentary by William H. Goldstein; (2) Groundbreaking Science with the World's Brightest X Rays - Experiments with x rays of unparalleled brightness and extremely short duration aim to reveal new information about atoms and molecules in motion; (3) From Data to Discovery - Ongoing control system enhancements at the National Ignition Facility bolster the understanding of experimental data and keep the system performing at its peak; (4) The Sun in All Its Splendor - Onboard the Solar Dynamics Observatory, Livermore-developed multilayer mirrors are enabling unprecedented full-disk, high-resolution images of the Sun; and (5) Drilling Deep into Plant Veins - A novel combination of imaging techniques is being used to understand the three-dimensional architecture of plant cell walls.

  4. Psychocapital and Shangri-Las: How happiness became both a means and end to governmentality

    Directory of Open Access Journals (Sweden)

    F. Mckay

    2013-11-01

    Full Text Available In this paper a paradox is revealed in the politics of well-being over the means and ends of happiness. That paradox, in brief, is that although happiness is argued to be the ultimate end of all governmentality, in order to serve as that end, it first needs to be translated into a means for bolstering the economy, for only that way can a teleology of happiness gain a foothold in a world which prioritizes economic growth as an end in itself. To show this the paper gives a history of subjective well-being (SWB research, and contrasts it with the politics of happiness in the UK, where SWB has in the past decade been translated into a discourse around the psychological wealth of the nation via the concepts of mental capital (MC and mental well-being (MWB.

  5. A Change for the Better

    DEFF Research Database (Denmark)

    Rozendal, Arjan; Lim, Eric T. K.; Tan, Chee-Wee

    2015-01-01

    argues for effective change management as a means for organizations to realize business-IT alignment. Findings from a grounded theory study revealed that having clear assessment criteria, promoting information exchange, getting managers to act as role models, expanding the involvement and participation...... of employees in decision making as well as drawing on positive collaborative experiences in the past bolster the success of change initiatives for realizing business-IT alignment. Conversely, pursuing partisan interest at the expense of the organization, speaking different professional languages, displaying......Investments in information technology will only yield dividends whenever technological spending complements corporate objectives, a phenomenon termed as business-IT alignment within extant literature. Synthesizing extant literature on business-IT alignment and organizational change, this paper...

  6. From Awareness to Cultural Agency: EFL Colombian Student Teachers’ Travelling Abroad Experiences

    Directory of Open Access Journals (Sweden)

    John Jairo Viafara González

    2015-01-01

    Full Text Available Colombian English as a foreign language student teachers’ opportunities to grow as educators through international sojourns do not usually subsume the traditional study and residence abroad goal. This was the case for our participants who engaged mainly in working abroad with study being ancillary. Fifty student teachers from two public universities reported how their international sojourn bolstered their intercultural learning. Three different programs, disconnected from participants’ academic institutions, became vehicles for their experiences abroad. Surveys and interviews reveal that participants’ origin, selected programs, and contextual circumstances influenced their intercultural learning. As a result, intercultural development gravitated towards awareness of intercultural patterns, critical reading of culture, and pre-service teachers’ repositioning to build cultural agency. Implications suggest the need to connect traveling abroad programs to undergraduate curricula.

  7. Land use and management change under climate change adaptation and mitigation strategies: a U.S. case study

    Science.gov (United States)

    Mu, Jianhong E.; Wein, Anne; McCarl, Bruce

    2015-01-01

    We examine the effects of crop management adaptation and climate mitigation strategies on land use and land management, plus on related environmental and economic outcomes. We find that crop management adaptation (e.g. crop mix, new species) increases Greenhouse gas (GHG) emissions by 1.7 % under a more severe climate projection while a carbon price reduces total forest and agriculture GHG annual flux by 15 % and 9 %, respectively. This shows that trade-offs are likely between mitigation and adaptation. Climate change coupled with crop management adaptation has small and mostly negative effects on welfare; mitigation, which is implemented as a carbon price starting at $15 per metric ton carbon dioxide (CO2) equivalent with a 5 % annual increase rate, bolsters welfare carbon payments. When both crop management adaptation and carbon price are implemented the effects of the latter dominates.

  8. Optimation of patient positioning and irradiation field documentation when irradiating in oto-rhino-laryngological area

    International Nuclear Information System (INIS)

    The large mobility of head and neck requires, when irradiating in this area, positioning and fastening aids, which go beyond simple head bolsters or head moulds. This paper presented describes a positioning system developed by us for irradiating the neck-nose-throat area, which, due to its construction, consists of a non-slipping positioning ground plate and an individually adjustable masking system, which is physiological safe, can be proceeded quickly and exactly, is relatively inexpensive, and is accepted by patients without objections, furthermore since skin markings by drawing field limits onto the face mask are no longer necessary. Various technical aids allow the placement of satellites to spare those body parts which are not irradiated and to installed compensators for the direction of radiation. An integrated cartridge mount enables in a simple way easy production of field control documentation photos. (orig.)

  9. A pilot feasibility study of a peer-led mindfulness program for medical students

    Science.gov (United States)

    Danilewitz, Marlon; Bradwejn, Jacques; Koszycki, Diana

    2016-01-01

    Background Mindfulness meditation has gained momentum in medical circles for bolstering wellbeing and other facets of professionalism. This study evaluated the feasibility and benefits of a peer-led mindfulness meditation program (MMP) on medical student wellness and professionalism. Method Pre-clerkship students were recruited and randomized to the 8-week MMP or wait-list. Feasibility outcomes included ease of recruitment, program attendance and homework compliance. Other outcomes included self-reported psychological distress, empathy, self-compassion, mindfulness, altruism and program satisfaction. Results The MMP decreased levels of stress and enhanced mindfulness, self-compassion and altruism from baseline to post-study. Changes were not significant for the wait-list condition. Although satisfaction with the MMP was high compliance was suboptimal. Conclusions A peer-led MMP is feasible and may be a promising approach to enhance medical student wellbeing. Further research is needed to explore strategies to improve program compliance in this student population. PMID:27103950

  10. Clinical Experience in TCM Treatment of Insomnia

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Insomnia is a sleeping disorder that affects 1 in 10 Americans and around 50% of the seniors. It is often more prevalent in women. Since September 11, 2005 these estimations have increased. Insomnia can affect not only your energy level and mood, but your health as well because sleep helps bolster your immune system. Insomnia is characterized by: 1) difficulty in falling asleep; 2) waking up frequently during the night with difficulty of returning to sleep; 3) waking up too early in the morning; and 4) with unrefreshing sleep, the patient has a low spirit, palpation, poor memory, viscera function disorder. All these seriously affect the patient's life and work. The following is an account of the authors' clinical TCM experience in treating insomnia.

  11. The Interaction of Language-Specific and Universal Factors During the Acquisition of Morphophonemic Alternations With Exceptions.

    Science.gov (United States)

    Baer-Henney, Dinah; Kügler, Frank; van de Vijver, Ruben

    2015-09-01

    Using the artificial language paradigm, we studied the acquisition of morphophonemic alternations with exceptions by 160 German adult learners. We tested the acquisition of two types of alternations in two regularity conditions while additionally varying length of training. In the first alternation, a vowel harmony, backness of the stem vowel determines backness of the suffix. This process is grounded in substance (phonetic motivation), and this universal phonetic factor bolsters learning a generalization. In the second alternation, tenseness of the stem vowel determines backness of the suffix vowel. This process is not based in substance, but it reflects a phonotactic property of German and our participants benefit from this language-specific factor. We found that learners use both cues, while substantive bias surfaces mainly in the most unstable situation. We show that language-specific and universal factors interact in learning. PMID:25546633

  12. Minimally invasive posterior hamstring harvest.

    Science.gov (United States)

    Wilson, Trent J; Lubowitz, James H

    2013-01-01

    Autogenous hamstring harvesting for knee ligament reconstruction is a well-established standard. Minimally invasive posterior hamstring harvest is a simple, efficient, reproducible technique for harvest of the semitendinosus or gracilis tendon or both medial hamstring tendons. A 2- to 3-cm longitudinal incision from the popliteal crease proximally, in line with the semitendinosus tendon, is sufficient. The deep fascia is bluntly penetrated, and the tendon or tendons are identified. Adhesions are dissected. Then, an open tendon stripper is used to release the tendon or tendons proximally; a closed, sharp tendon stripper is used to release the tendon or tendons from the pes. Layered, absorbable skin closure is performed, and the skin is covered with a skin sealant, bolster dressing, and plastic adhesive bandage for 2 weeks. PMID:24266003

  13. Science and Technology Review January/February 2011

    Energy Technology Data Exchange (ETDEWEB)

    Blobaum, K J

    2010-11-22

    This month's issue has the following articles: (1) World's Most Intense X-Ray Laser Focuses on Livermore Science - Commentary by William H. Goldstein; (2) Groundbreaking Science with the World's Brightest X Rays - Experiments with x rays of unparalleled brightness and extremely short duration aim to reveal new information about atoms and molecules in motion; (3) From Data to Discovery - Ongoing control system enhancements at the National Ignition Facility bolster the understanding of experimental data and keep the system performing at its peak; (4) The Sun in All Its Splendor - Onboard the Solar Dynamics Observatory, Livermore-developed multilayer mirrors are enabling unprecedented full-disk, high-resolution images of the Sun; and (5) Drilling Deep into Plant Veins - A novel combination of imaging techniques is being used to understand the three-dimensional architecture of plant cell walls.

  14. From Slash-and-burn to Disk Ploughing: The Land Policy and Tractors Behind Erosion and Forest Pioneer Farming in Southern Xayabury Province (Laos

    Directory of Open Access Journals (Sweden)

    Marc Dufumier

    2013-02-01

    Full Text Available Bordering Thailand, the southern part of Xayabury province is engaged in international trade and has experienced agricultural growth like nowhere else in Laos. The rapid transformation from manual slash-and-burn agriculture to mechanized, chemical-based cropping systems is often cited by Laotian authorities as a model of development. But a careful study of changes underway indicates that the reality is far less encouraging than it would appear at first. If many farmers have indeed bolstered their incomes over the last twenty years, it is no less true that some of the poorest peasants have become increasingly poorer and that the new techniques cause serious erosion, as they have not been able to prevent the expansion of cultivated areas on sloping lands.

  15. The Individuals With Disabilities Education Act (IDEA) for Children With Special Educational Needs.

    Science.gov (United States)

    Lipkin, Paul H; Okamoto, Jeffrey

    2015-12-01

    The pediatric health care provider has a critical role in supporting the health and well-being of children and adolescents in all settings, including early intervention (EI), preschool, and school environments. It is estimated that 15% of children in the United States have a disability. The Individuals with Disabilities Education Act entitles every affected child in the United States from infancy to young adulthood to a free appropriate public education through EI and special education services. These services bolster development and learning of children with various disabilities. This clinical report provides the pediatric health care provider with a summary of key components of the most recent version of this law. Guidance is also provided to ensure that every child in need receives the EI and special education services to which he or she is entitled. PMID:26620061

  16. Crafting AIDS policy in Brazil and Russia: State-civil societal ties, institutionalised morals, and foreign policy aspiration.

    Science.gov (United States)

    Gómez, Eduardo J

    2016-10-01

    During the 1990s, Brazil and Russia diverged in their policy response to AIDS. This is puzzling considering that both nations were globally integrated emerging economies transitioning to democracy. This article examines to what extent international pressures and partnerships with multilateral donors motivated these governments to increase and sustain federal spending and policy reforms. Contrary to this literature, the cases of Brazil and Russia suggest that these external factors were not important in achieving these outcomes. Furthermore, it is argued that Brazil's policy response was eventually stronger than Russia's and that it had more to do with domestic political and social factors: specifically, AIDS officials' efforts to cultivate a strong partnership with NGOs, the absence of officials' moral discriminatory outlook towards the AIDS community, and the government's interest in using policy reform as a means to bolster its international reputation in health. PMID:27564438

  17. Resilience, integrated development and family planning: building long-term solutions.

    Science.gov (United States)

    De Souza, Roger-Mark

    2014-05-01

    For the many individuals and communities experiencing natural disasters and environmental degradation, building resilience means becoming more proficient at anticipating, preventing, recovering, and rebuilding following negative shocks and stresses. Development practitioners have been working to build this proficiency in vulnerable communities around the world for several decades. This article first examines the meaning of resilience as a component of responding to disasters and some of the key components of building resilience. It then summarises approaches to resilience developed by the Rockefeller and Packard Foundations, the Intergovernmental Panel on Climate Change, USAID and DFID, which show how family planning services can contribute to resilience. Next, it gives some examples of how family planning has been integrated into some current environment and development programmes. Finally, it describes how these integrated programmes have succeeded in helping communities to diversify livelihoods, bolster community engagement and resilience, build new governance structures, and position women as agents of change. PMID:24908458

  18. March of the living, a holocaust educational tour: effect on adolescent Jewish identity.

    Science.gov (United States)

    Nager, Alan L; Pham, Phung; Gold, Jeffrey I

    2013-12-01

    March of the Living (MOTL) is a worldwide two-week trip for high school seniors to learn about the Holocaust by traveling to sites of concentration/death camps and Jewish historical sites in Poland and Israel. The mission statement of MOTL International states that participants will be able to "bolster their Jewish identity by acquainting them with the rich Jewish heritage in pre-war Eastern Europe." However, this claim has never been studied quantitatively. Therefore, 152 adolescents who participated in MOTL voluntarily completed an initial background questionnaire, a Jewish Identity Survey and a Global Domains Survey pre-MOTL, end-Poland and end-Israel. Results suggest that Jewish identity did not substantially increase overall or from one time period to the next. PMID:23801019

  19. Effects of competition on video-task performance in monkeys (Macaca mulatta)

    Science.gov (United States)

    Washburn, David A.; Hopkins, William D.; Rumbaugh, Duane M.

    1990-01-01

    The effects of competition on performance of a video-formatted task were examined in a series of experiments. Two rhesus monkeys (Macaca mulatta) were trained to manipulate a joystick to shoot at moving targets on a computer screen. The task was made competitive by requiring both animals to shoot at the same target and by rewarding only the animal that hit the target first each trial. The competitive task produced a significant and robust speed-accuracy trade-off in performance. The monkeys hit the target in significantly less time on contested than on uncontested trials. However, they required significantly more shots to hit the target on contested trials in relation to uncontested trials. This effect was unchanged when various schedules of reinforcement were introduced in the uncontested trials. This supports the influence of competition qua competition on performance, a point further bolstered by other findings of behavioral contrast presented here.

  20. Compassion fatigue and burnout: what managers should know.

    Science.gov (United States)

    Slatten, Lise Anne; David Carson, Kerry; Carson, Paula Phillips

    2011-01-01

    Most health care employees experience and are bolstered by compassion satisfaction as they deal with patients in need. However, the more empathetic a health care provider is, the more likely he or she will experience compassion fatigue. Compassion fatigue is a negative syndrome that occurs when dealing with the traumatic experiences of patients, and examples of symptoms include intrusive thoughts, sleeping problems, and depression. Compassion fatigue is different from burnout. Compassion fatigue is a rapidly occurring disorder for primary health care workers who work with suffering patients, whereas burnout, a larger construct, is a slowly progressing disorder for employees who typically are working in burdensome organizational environments. Managers can mitigate problems associated with compassion fatigue with a number of interventions including patient reassignments, formal mentoring programs, employee training, and a compassionate organizational culture. With burnout, health care managers will want to focus primarily on chronic organizational problems. PMID:22042140

  1. LGBT community, social network characteristics, and smoking behaviors in young sexual minority women.

    Science.gov (United States)

    Johns, Michelle Marie; Pingel, Emily S; Youatt, Emily J; Soler, Jorge H; McClelland, Sara I; Bauermeister, Jose A

    2013-09-01

    Smoking rates among young sexual minority women (YSMW) are disproportionately high as compared to heterosexual populations. While this disparity has commonly been attributed to the sexual minority stress process, little empirical work has explored what may protect YSMW from high rates of smoking. Using data (N = 471) from a cross-sectional study designed to investigate YSMW's (age 18-24) smoking behaviors and correlates; we explore the relationship of LGBT community connections, YSMW's social network characteristics, and stress to smoking behaviors (i.e., status, frequency, amount). Through this analysis, we find support for LGBT community connection as well as friendships with other sexual minorities as protective in relation to YSMW's smoking behaviors. We discuss the implications of our results, highlighting the need for future longitudinal research and interventions designed to bolster YSMW's connections to the LGBT community and their social networks. PMID:23783884

  2. Claudia Quinta (Pro Caelio 34 and an altar to Magna Mater

    Directory of Open Access Journals (Sweden)

    Eleanor Winsor Leach

    2010-11-01

    Full Text Available Among the items of sculpture from the Capitoline collection now housed in the Museum of the Power Station Montemartini is a marble relief altar of the Claudian Period (E. Simon's dating dedicated to the mater deorum and the navis salvia and depicting the arrival of the goddess Cybele at Rome by ship. The dedicator is one Claudia Syntyche and the sculpture alludes to the legends attached to a much honored woman of the Claudian family whom Cicero, in his oration pro Caelio brought on stage in a cameo appearance to bolster his case against the controversial contemporary woman Clodia Metelli as one of the accusers of his client M. Caelius Rufus. This paper will consider questions raised by the iconography of the altar with reference to the development of Claudia's legend in Roman mythology and subsequently ask who was this Claudia the dedicator and why did she choose Magna Mater for her vow?

  3. Health care and family support systems of functionally impaired rural elderly men and women in Terengganu, Malaysia.

    Science.gov (United States)

    Tracy, M B; Tracy, P D

    1993-01-01

    This article examines the health and social support systems of a small survey sample of rural, low-income, functionally impaired elderly persons in the state of Terengganu, Malaysia. Increases in the number and proportion of the elderly are a growing concern, especially in rural areas where there are indications that traditional care givers (daughters) for the elderly are migrating to urban areas. The out-migration patterns in this survey, however, were less than expected. In general, the needs of the respondents are being met by multiple in-kind assistance from adult children, spouses, relatives, friends and neighbors bolstered by free government health care and cash assistance programs. The survey does raise serious concerns regarding the utilization of health care facilities by women, the negative impact of detrimental myths about aging, and the need for more visiting nurses and mobile clinics. PMID:24389755

  4. How to shape positive relationships in medical practices and hospitals.

    Science.gov (United States)

    Sotile, W M; Sotile, M O

    1999-01-01

    Managing workplace conflict is one of the most important, stressful, and time-consuming tasks faced by today's medical leaders. Poorly managed workplace conflict can alienate patients, demoralize staff, increase turnover, damage relationships with valued referral sources and third party carriers concerned about patient satisfaction, and lead medical practices to costly "corporate divorces." Physician executives cannot solve the problems caused by disruptive doctors simply by bolstering their own conflict management skills or by policing offenders. The larger contexts within which inappropriate workplace behavior occurs must also be assessed and addressed. The true leadership challenge is to intervene in ways that help to foster a "culture" of appropriate interpersonal dynamics throughout your organization. This requires learning to think and to intervene systematically. PMID:10557487

  5. Quantifying crustal thickness over time in magmatic arcs

    Science.gov (United States)

    Profeta, Lucia; Ducea, Mihai N.; Chapman, James B.; Paterson, Scott R.; Gonzales, Susana Marisol Henriquez; Kirsch, Moritz; Petrescu, Lucian; DeCelles, Peter G.

    2015-01-01

    We present global and regional correlations between whole-rock values of Sr/Y and La/Yb and crustal thickness for intermediate rocks from modern subduction-related magmatic arcs formed around the Pacific. These correlations bolster earlier ideas that various geochemical parameters can be used to track changes of crustal thickness through time in ancient subduction systems. Inferred crustal thicknesses using our proposed empirical fits are consistent with independent geologic constraints for the Cenozoic evolution of the central Andes, as well as various Mesozoic magmatic arc segments currently exposed in the Coast Mountains, British Columbia, and the Sierra Nevada and Mojave-Transverse Range regions of California. We propose that these geochemical parameters can be used, when averaged over the typical lifetimes and spatial footprints of composite volcanoes and their intrusive equivalents to infer crustal thickness changes over time in ancient orogens. PMID:26633804

  6. The evolution of index signals to avoid the cost of dishonesty.

    Science.gov (United States)

    Biernaskie, Jay M; Grafen, Alan; Perry, Jennifer C

    2014-09-01

    Animals often convey useful information, despite a conflict of interest between the signaller and receiver. There are two major explanations for such 'honest' signalling, particularly when the size or intensity of signals reliably indicates the underlying quality of the signaller. Costly signalling theory (including the handicap principle) predicts that dishonest signals are too costly to fake, whereas the index hypothesis predicts that dishonest signals cannot be faked. Recent evidence of a highly conserved causal link between individual quality and signal growth appears to bolster the index hypothesis. However, it is not clear that this also diminishes costly signalling theory, as is often suggested. Here, by incorporating a mechanism of signal growth into costly signalling theory, we show that index signals can actually be favoured owing to the cost of dishonesty. We conclude that costly signalling theory provides the ultimate, adaptive rationale for honest signalling, whereas the index hypothesis describes one proximate (and potentially very general) mechanism for achieving honesty. PMID:25056623

  7. The physician charter on medical professionalism from the Chinese perspective: a comparative analysis.

    Science.gov (United States)

    Jin, Pingyue

    2015-07-01

    The charter of medical professionalism in the new millennium (Charter) has been endorsed worldwide, including by the Chinese Medical Doctor Association from 2005. Six years later, the association drafted a Chinese version of medical professionalism based on the Charter, the Chinese Medical Doctor Declaration (Declaration). This Declaration encompasses six tenets, which have large areas of overlap with the Charter. Meanwhile, certain differences also exist between the universal professionalism that the Charter aims to disseminate and the ideal Chinese professionalism that the Declaration endeavours to bolster. In this paper, we explore the unique aspects of the Declaration in contrast with the Charter to gain a deeper understanding of professionalism in the particular context of China. The Declaration may omit some valuable commitments found in the Charter, but it includes longstanding Confucian and cultural traditions of China, as well as consideration of current social circumstances. The Declaration thus re-establishes the ideal of universal professionalism in light of the Chinese context. PMID:25341734

  8. Using communities that care for community child maltreatment prevention.

    Science.gov (United States)

    Salazar, Amy M; Haggerty, Kevin P; de Haan, Benjamin; Catalano, Richard F; Vann, Terri; Vinson, Jean; Lansing, Michaele

    2016-03-01

    The prevention of mental, emotional, and behavioral (MEB) disorders among children and adolescents is a national priority. One mode of implementing community-wide MEB prevention efforts is through evidence-based community mobilization approaches such as Communities That Care (CTC). This article provides an overview of the CTC framework and discusses the adaptation process of CTC to prevent development of MEBs through preventing child abuse and neglect and bolstering child well-being in children aged 0 to 10. Adaptations include those to the intervention itself as well as those to the evaluation approach. Preliminary findings from the Keeping Families Together pilot study of this evolving approach suggest that the implementation was manageable for sites, and community board functioning and community adoption of a science-based approach to prevention in pilot sites looks promising. Implications and next steps are outlined. (PsycINFO Database Record PMID:26963184

  9. Mental Health Promotion in Public Health: Perspectives and Strategies From Positive Psychology

    Science.gov (United States)

    Seligman, Martin E.P.; Peterson, Christopher; Diener, Ed; Zack, Matthew M.; Chapman, Daniel; Thompson, William

    2011-01-01

    Positive psychology is the study of what is “right” about people—their positive attributes, psychological assets, and strengths. Its aim is to understand and foster the factors that allow individuals, communities, and societies to thrive. Cross-sectional, experimental, and longitudinal research demonstrates that positive emotions are associated with numerous benefits related to health, work, family, and economic status. Growing biomedical research supports the view that positive emotions are not merely the opposite of negative emotions but may be independent dimensions of mental affect. The asset-based paradigms of positive psychology offer new approaches for bolstering psychological resilience and promoting mental health. Ultimately, greater synergy between positive psychology and public health might help promote mental health in innovative ways. PMID:21680918

  10. Playing Games with the Quantum Three-Body Problem

    CERN Document Server

    Biswas, T

    2004-01-01

    Quantum mechanics courses focus mostly on its computational aspects. This alone does not provide the same depth of understanding as most physicists have of classical mechanics. The understanding of classical mechanics is significantly bolstered by the intuitive understanding that one acquires through the playing of games like baseball at an early age. It would be good to have similar games for quantum mechanics. However, real games that involve quantum phenomena directly are impossible. So, computer simulated games are good alternatives. Here a computer game involving three interacting quantum particles is discussed. It is hoped that such games played at an early age will provide the intuitive background for a better understanding of quantum mechanics at a later age.

  11. Little Ice Age wetting of interior Asian deserts and the rise of the Mongol Empire

    Science.gov (United States)

    Putnam, Aaron E.; Putnam, David E.; Andreu-Hayles, Laia; Cook, Edward R.; Palmer, Jonathan G.; Clark, Elizabeth H.; Wang, Chunzeng; Chen, Feng; Denton, George H.; Boyle, Douglas P.; Bassett, Scott D.; Birkel, Sean D.; Martin-Fernandez, Javier; Hajdas, Irka; Southon, John; Garner, Christopher B.; Cheng, Hai; Broecker, Wallace S.

    2016-01-01

    The degree to which warming of the planet will alter Asia's water resources is an important question for food, energy, and economic security. Here we present geological evidence, underpinned by radiometric dating and dendrochronology, and bolstered by hydrological modeling, indicating that wetter-than-present conditions characterized the core of the inner Asian desert belt during the Little Ice Age, the last major Northern Hemispheric cold spell of the Holocene. These wetter conditions accompanied northern mid-latitude cooling, glacier expansion, a strengthened/southward-shifted boreal jet, and weakened south Asian monsoons. We suggest that southward migration of grasslands in response to these wetter conditions aided the spread of Mongol Empire steppe pastoralists across Asian drylands. Conversely, net drying over the 20th century has led to drought that is unprecedented for the past ∼830 years, and that could intensify with further heating of the Asian continent.

  12. Materials for Active Engagement in Nuclear and Particle Physics Courses

    Science.gov (United States)

    Loats, Jeff; Schwarz, Cindy; Krane, Ken

    2013-04-01

    Physics education researchers have developed a rich variety of research-based instructional strategies that now permeate many introductory courses. Carrying these active-engagement techniques to upper-division courses requires effort and is bolstered by experience. Instructors interested in these methods thus face a large investment of time to start from scratch. This NSF-TUES grant, aims to develop, test and disseminate active-engagement materials for nuclear and particle physics topics. We will present examples of these materials, including: a) Conceptual discussion questions for use with Peer Instruction; b) warm-up questions for use with Just in Time Teaching, c) ``Back of the Envelope'' estimation questions and small-group case studies that will incorporate use of nuclear and particle databases, as well as d) conceptual exam questions.

  13. Partial nephrectomy in a patient with a left ventricular assist device.

    Science.gov (United States)

    Manger, Jules P; Kern, John A; Krupski, Tracey L

    2011-01-01

    Left ventricular assist device (LVAD) use has increased as a bridge to heart transplant as well as destination therapy in patients with severe heart failure. Presence of LVAD is not a contraindication to noncardiac surgery but does present special challenges to the surgical, anesthesia, and cardiac teams. We present the case of a 40-year-old woman with idiopathic cardiomyopathy necessitating LVAD who underwent left partial nephrectomy for a renal mass. She had undergone three nondiagnostic percutaneous image-guided biopsies. Left partial nephrectomy was performed. Perioperative care was without incident due to careful oversight by a multidisciplinary team. Pathology revealed high-grade clear cell renal cell carcinoma (RCC) with negative margins. Polytetrafluoroethylene (PTFE) bolsters were misidentified six months postoperatively on computed tomography (CT) at an outside institution as a retained laparotomy sponge. This is, to our knowledge, the first report of a partial nephrectomy performed in a patient with LVAD. PMID:22606616

  14. Structure of the T6SS lipoprotein TssJ1 from Pseudomonas aeruginosa

    International Nuclear Information System (INIS)

    The crystal structure of the type VI secretion-system protein TssJ1 from P. aeruginosa was solved by iodide SAD at a resolution of 1.4 Å. The type VI secretion system of Pseudomonas aeruginosa has been shown to be responsible for the translocation of bacteriolytic effectors into competing bacteria. A mechanistic understanding of this widely distributed secretion system is developing and structural studies of its components are ongoing. Two representative structures of one highly conserved component, TssJ, from Escherichia coli and Serratia marcescens have been published. Here, the X-ray crystal structure of TssJ1 from P. aeruginosa is presented at 1.4 Å resolution. The overall structure is conserved among the three proteins. This finding suggests that the homologues function in a similar manner and bolsters the understanding of the structure of this family of proteins

  15. You didn't have to do that: belief in free will promotes gratitude.

    Science.gov (United States)

    MacKenzie, Michael J; Vohs, Kathleen D; Baumeister, Roy F

    2014-11-01

    Four studies tested the hypothesis that a weaker belief in free will would be related to feeling less gratitude. In Studies 1a and 1b, a trait measure of free will belief was positively correlated with a measure of dispositional gratitude. In Study 2, participants whose free will belief was weakened (vs. unchanged or bolstered) reported feeling less grateful for events in their past. Study 3 used a laboratory induction of gratitude. Participants with an experimentally reduced (vs. increased) belief in free will reported feeling less grateful for the favor. In Study 4, a reduced (vs. increased) belief in free will led to less gratitude in a hypothetical favor scenario. This effect was serially mediated by perceiving the benefactor as having less free will and therefore as being less sincerely motivated. These findings suggest that belief in free will is an important part of being able to feel gratitude. PMID:25209516

  16. Gallinacin and Fowlicidin: Two Promising Antimicrobial Peptides in ChickensAND#8212;A Review

    Directory of Open Access Journals (Sweden)

    C. S. Mukhopadhyaya

    2010-12-01

    Full Text Available Antimicrobial peptides (AMP which have been identified in almost all groups of organisms, are the small cationic molecules that recognize the pathogen associated molecular patterns of the microbes. In chicken two main AMPs that play significant roles in bolstering the innate immunity are gallinacins and fowlicidins, which are the functional analogues of the mammalian beta-defensins and cathelicidins. Gallinacin identifies the Gram negative bacteria while fowlicidin exerts broad spectral activity. The basic mechanism of action is by far similar in both groups of AMPs. The ‘docking sites’ of these antimicrobial peptides includes the “lipid A” moiety of lipo polysaccharides, lipo-teichoic acids, anionic membrane phospholipids on bacterial surfaces. These AMPs block the DNA replication and protein synthesis in bacteria causing death of the microbe. Researchers have identified reproducible molecular markers of those peptides for selection of disease resistant stock of chickens. [Vet. World 2010; 3(6.000: 297-300

  17. Clean Energy Manufacturing: U.S. Competitiveness and State Policy Strategies (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Lantz, E.

    2014-02-01

    The capital intensive nature of clean energy technologies suggests that manufacturing clean energy equipment has the potential to support state and local economic development efforts. However, manufacturing siting decisions tend to be complex and multi-variable decision processes that require in-depth knowledge of specific markets, the logistical requirements of a given technology, and insight into global clean tech trends. This presentation highlights the potential of manufacturing in supporting economic development opportunities while also providing examples of the financial considerations affecting manufacturing facility siting decisions for wind turbine blades and solar PV. The presentation also includes discussion of other more qualitative drivers of facility siting decisions as gleaned from NREL industry interviews and discusses strategies state and local policymakers may employee to bolster their chances of successfully attracting clean energy manufacturers to their localities.

  18. mRNA Transfection to Improve NK Cell Homing to Tumors.

    Science.gov (United States)

    Levy, Emily R; Carlsten, Mattias; Childs, Richard W

    2016-01-01

    The ability of natural killer (NK) cells to mediate antitumor effects following adoptive transfer is dependent on their capacity to traffic to the microenvironment where tumors reside. Recent studies have shown that cytokine-activated and ex vivo-expanded NK cells lack or express at low levels homing receptors required to achieve tissue-specific tumor targeting by cells administered intravenously. In this chapter, we describe a method to enhance NK cell homing toward specific chemoattractants expressed in secondary lymphoid tissues through genetic modification of NK cells using mRNA electroporation. The method described here is scalable, cGMP-compliant, and offers a strategy to bolster the efficacy of adoptive NK cell immunotherapy for the treatment of hematological malignancies in the clinic. PMID:27177670

  19. Application and Utility of Psychodynamic Principles in Forensic Assessment.

    Science.gov (United States)

    Simopoulos, Eugene F; Cohen, Bruce

    2015-12-01

    Effective practice of forensic psychiatry is dependent on a clinical recognition and understanding of core psychodynamic principles and theory. Practice guidelines, rooted in the ethics-based imperative to strive for honesty and objectivity, demand that practitioners remain vigilant to the development of bias and appreciate interpersonal dynamics that may be re-enacted in the forensic setting. Although it is not feasible to maintain complete impartiality, especially when confronted with the nature of certain offenses, knowledge of both conscious and unconscious responses can bolster the intellectual integrity of the clinical assessment. The identification of defense mechanisms within both the evaluator and evaluee and attention to transference and countertransference are essential for an accurate conceptualization of an offender's psychological functioning, vulnerabilities, and risk of reoffense. In this article, we review psychodynamic concepts and their potential impact in the forensic setting and underscore interventions that may aid in the elucidation and management of these processes. PMID:26668219

  20. EXPORTS, FOREIGN DIRECT INVESTMENT AND ECONOMIC GROWTH: EMPIRICAL EVIDENCE FROM MALAYSIA (1971-2013

    Directory of Open Access Journals (Sweden)

    Muhammad Haseeb

    2014-01-01

    Full Text Available The main objective of this study is to empirically investigate the relationship between exports, Foreign Direct Investment (FDI and the economic growth in Malaysia. Records of annual time series data from the year 1971 till 2013 have been utilized for this purpose. Upon testing the data for stationarity, the Auto Regressive Distributed Lag (ARDL model has been applied for the purpose of empirical investigation. The empirical results indicate that the productivity factor and externality effect of exports on the non-export sector are found to be statistically, positively significant, with the exports also having a positive impact on the economic growth and FDI of the country. The results support Exports Led Growth (ELG and FDI-Led economic Growth (FLG in Malaysia. The finding further suggests that Malaysia should continuous pursue exports promotion and a liberal investment economic policy in order to maintain and bolster overall economic growth.

  1. Managing CSR Globally and Locally

    DEFF Research Database (Denmark)

    L. Brown, Dana; Knudsen, Jette Steen

    Corporate Responsibility (CR) is today an essential component of corporate global strategy. CR can bolster the institutional context for market expansion (Porter and Kramer 2006); fill institutional voids (Tarun, et.al. 2005); or facilitate market entry as a component of non-market strategy (Baron...... 2006). Yet, in fulfilling these functions, CR may need to be highly sensitive to local contexts. How can transnational firms organize CR so as to maximize efficiencies from globalization and to minimize the fragmentation of corporate organizational cultures? Bartlett and Ghoshal (1989) provide a...... framework for analyzing the way that corporations coordinate global and local functions. We build on this framework in a case study of Novo Nordisk and its approach to determining global and local CR policies and procedures with regard to its China and United States subsidiaries. Our findings suggest that...

  2. Managing Corporate Responsibility Globally and Locally

    DEFF Research Database (Denmark)

    Brown, Dana; Knudsen, Jette Steen

    2012-01-01

    Corporate Responsibility (CR) is today an essential component of corporate global strategy. CR can bolster the institutional context for market expansion fill institutional voids or facilitate market entry as a component of non-market strategy. Yet, in fulfilling these functions, CR may need to be...... highly sensitive to local contexts. How can transnational firms organize CR so as to maximize efficiencies from globalization and to minimize the fragmentation of corporate organizational cultures? provide a framework for analyzing the way that corporations coordinate global and local functions. We build...... on this framework in a case study of Novo Nordisk and its approach to determining global and local CR policies and procedures with regard to its China and US subsidiaries. Our findings suggest that it is important for companies to define a common set of organizational norms. In addition, CR need to...

  3. Curtis's cephaloscope: deafness and the making of surgical authority in London, 1816-1845.

    Science.gov (United States)

    Virdi-Dhesi, Jaipreet

    2013-01-01

    Aural surgery is a branch of nineteenth-century medicine and surgery providing specialized treatment for ear diseases. During the 1830s, faced with a "popular prejudice" against the curability of deafness as well as intraprofessional rivalries and continuous accusations of quackery, aurists found their surgical authority questioned and their field's value threatened. In an attempt to bolster aural surgery's reputation, in 1841, the aurist John Harrison Curtis (1778-1856) introduced his new diagnostic instrument, the cephaloscope, which could not only improve diagnosis but also provide approaches for regulating aural knowledge, thus strengthening aural surgery's authority. This article examines the motives underlying Curtis's introduction of the cephaloscope and the meanings it held for the occupational group at large. PMID:24096558

  4. Commentary on Alcorn & Massé: troubling pedagogy

    Directory of Open Access Journals (Sweden)

    Michael O’Loughlin

    2011-12-01

    Full Text Available Responding to papers by Michelle Massé and Marshall Alcorn, I begin with an argument for the need to recognize ignorance as performative rather than merely as illustrative of student resistance in some pathological sense. I then explore the Lacanian notion that teachers develop imaginary suppositions about the lack in their students, and that these suppositions support rescue fantasies among teachers that are related to bolstering their own unconscious need for narcissistic gratification and love. I conclude by showing how these ideas resonate with my own autobiographical history as a teacher, as well as with key ideas in the two papers under discussion, and I commend both authors for opening up a valuable discussion of teaching as an “impossible profession”.

  5. The Australian Hydrogen and Fuel Cells Education Program

    International Nuclear Information System (INIS)

    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  6. Bounded agency in humanitarian settings: a qualitative study of adherence to antiretroviral therapy among refugees situated in Kenya and Malaysia.

    Science.gov (United States)

    Mendelsohn, Joshua B; Rhodes, Tim; Spiegel, Paul; Schilperoord, Marian; Burton, John Wagacha; Balasundaram, Susheela; Wong, Chunting; Ross, David A

    2014-11-01

    HIV-positive refugees confront a variety of challenges in accessing and adhering to antiretroviral therapy (ART) and attaining durable viral suppression; however, there is little understanding of what these challenges are, how they are navigated, or how they may differ across humanitarian settings. We sought to document and examine accounts of the threats, barriers and facilitators experienced in relation to HIV treatment and care and to conduct comparisons across settings. We conducted semi-structured interviews among a purposive sample of 14 refugees attending a public, urban HIV clinic in Kuala Lumpur, Malaysia (July-September 2010), and 12 refugees attending a camp-based HIV clinic in Kakuma, Kenya (February-March 2011). We used framework methods and between-case comparison to analyze and interpret the data, identifying social and environmental factors that influenced adherence. The multiple issues that threatened adherence to antiretroviral therapy or precipitated actual adherence lapses clustered into three themes: "migration", "insecurity", and "resilience". The migration theme included issues related to crossing borders and integrating into treatment systems upon arrival in a host country. Challenges related to crossing borders were reported in both settings, but threats pertaining to integration into, and navigation of, a new health system were exclusive to the Malaysian setting. The insecurity theme included food insecurity, which was most commonly reported in the Kenyan setting; health systems insecurity, reported in both settings; and emotional insecurity, which was most common in the Kenyan setting. Resilient processes were reported in both settings. We drew on the concept of "bounded agency" to argue that, despite evidence of personal and community resilience, these processes were sometimes insufficient for overcoming social and environmental barriers to adherence. In general, interventions might aim to bolster individuals' range of action with

  7. The Australian Hydrogen and Fuel Cells Education Program

    Energy Technology Data Exchange (ETDEWEB)

    Luigi Bonadio [Senior Consultant Luigi Bonadio and Associates (Australia)

    2006-07-01

    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  8. DYNAMICS OF FREIGHT CARS ON BOGIES MODEL 18-1711 WITH DIFFERENT WEDGE DE-SIGNS OF SPRING SUSPENSION

    Directory of Open Access Journals (Sweden)

    N. B. Mankevych

    2014-01-01

    Full Text Available Purpose. To analyze the results of the study of dynamic parameters of a gondola car, model 12-1704-04 with axle load 23.5 ton in bogies, models 18-1750 and two gondola cars, model 12-1905 with axial load of 25 ton, one of which is equipped with bogies, model 18-1711 with friction wedges of spring suspension with spatial form with increased angle to the horizontal line of intersection of the contact surfaces between the wedge and bolster, the other gondola car, model 12-1905 is equipped with bogies of the same model on which the friction wedges fitted with a flat form of contact surface. It has an angle of inclination like a wedge of bogie, model 18-100. On the basis of the obtained results to draw conclusions about the feasibility of unification design bogie bolster, model 18-1711 with bogie, model 18-100 by contact surfaces with elements of spring suspension. Methodology. Research on dynamic performance of cars was performed during running dynamic tests of specimens of freight cars in experimental train consisting of two locomotives, a laboratory, and three gondola cars of the above mentioned models. Findings. Main results of dynamic studies are presented as graphs of indicators on the speed of the train and the experimental evidence that the freight gondola cars on bogies, model 18-1711 with flat-shaped wedges, in most cases are better than the others. Originality. Research results of cars on bogies, model 18-1711 were obtained. They let assess the dependence of the dynamic performance of the car from the design of the friction wedges of spring suspension. Practical value. Cast parts of bogie, model 18-1711 with 25 ton axle load can be used as a replacement of defective parts of bogie, model 18-100 and its analogs.

  9. Upper lid crease approach for margin rotation in trachomatous cicatricial entropion without external sutures

    Directory of Open Access Journals (Sweden)

    Antonio Augusto Velasco e Cruz

    2015-12-01

    Full Text Available ABSTRACT Purpose: To describe the use of a lid crease incision for upper eyelid margin rotation in cicatricial entropion combining internal traction on the anterior lamella, tarsotomy, and tarsal overlap without external sutures. Methods: Surgical description: The main steps of the procedure consisted of exposure of the entire tarsal plate up to the eyelashes followed by tarsotomy through the conjunctiva. A double-armed 6.0 polyglactin suture was then passed through the distal tarsal fragment to the marginal section of the orbicularis oculi muscle. As the sutures were tied, the distal tarsus advanced over the marginal section, and traction was exerted on the marginal strip of the orbicularis muscle. There were no bolsters or external knots. The pretarsal skin-muscle flap was closed with a 6.0 plain gut suture. Results: We used this procedure at a tertiary hospital in Saudi Arabia from 2013 to 2014. Sixty upper lids of 40 patients (23 women and 17 men were operated on, with an age range of 44-99 years [mean ± standard deviation (SD = 70.9 ± 13.01 years]. Bilateral surgery was performed on 21 patients. Follow-up ranged from 1 to 12 months (mean 3.0 ± 2.71 months. Forty percent of the patients (24 lids had more than 3 months' follow-up. The postoperative lid margin position was good in all cases. Trichiasis (two lashes was observed in only one patient with unilateral entropion on the medial aspect of the operated lid. Conclusions: The upper lid margin can be effectively rotated through a lid crease incision with internal sutures. The technique combines the main mechanisms of the Wies and Trabut approaches and avoids the use of bolsters or external sutures, which require a second consultation to be removed. Some other lid problems, such as ptosis, retraction, or dermatochalasis, can be concomitantly addressed during the procedure.

  10. Fiscal and Macroeconomic Effects of Colombia`s Pension Reform Fiscal and Macroeconomic Effects of Colombia`s Pension Reform

    Directory of Open Access Journals (Sweden)

    Klaus Schmidt-Hebbel

    1997-03-01

    Full Text Available In 1994 Colombia started replacing its state-run and pay-as-you-go (PAYG pension system by a privately-run and fully-funded scheme. Numerical simulations for the government's reform transition reveal implicit PAYG debt levels and corresponding reform transition deficits that are high relative to other countries, considering that Colombia's old pension system was characterized by low coverage, low system maturity, and a young population.Simulation results show that output could increase by 10% due to higher future saving caused by financing the pension deficit by a fiscal contraction -but this would occur only in the very long term. Sooner and possibly larger gains could be reaped from higher employment and production in formal sectors, and the development of capital markets spurred by the reform. In addition, Colombia's new pension systemthat includes a redistributive pillar targeted at the poor -is potentially more equitable than the old scheme, To reap these efficiency and equity bellefits, however, the Colombian government would have to adopt complementary reforms. They include giving the private fully-funded pension pillar a commanding role, supporting the development of capital markets, and bolstering formal-sector employment by the reduction of deadweight tax burden of non-pension programs that are currently financed by payroll taxes on labor. In 1994 Colombia started replacing its state-run and pay-as-you-go (PAYG pension system by a privately-run and fully-funded scheme. Numerical simulations for the government's reform transition reveal implicit PAYG debt levels and corresponding reform transition deficits that are high relative to other countries, considering that Colombia's old pension system was characterized by low coverage, low system maturity, and a young population.Simulation results show that output could increase by 10% due to higher future saving caused by financing the pension deficit by a fiscal contraction -but this would

  11. Noninvasive low-level laser therapy for thrombocytopenia.

    Science.gov (United States)

    Zhang, Qi; Dong, Tingting; Li, Peiyu; Wu, Mei X

    2016-07-27

    Thrombocytopenia is a common hematologic disorder that is managed primarily by platelet transfusions. We report here that noninvasive whole-body illumination with a special near-infrared laser cures acute thrombocytopenia triggered by γ-irradiation within 2 weeks in mice, as opposed to a 5-week recovery time required in controls. The low-level laser (LLL) also greatly accelerated platelet regeneration in the presence of anti-CD41 antibody that binds and depletes platelets, and prevented a severe drop in platelet count caused by a common chemotherapeutic drug. Mechanistically, LLL stimulated mitochondrial biogenesis specifically in megakaryocytes owing to polyploidy of the cells. LLL also protected megakaryocytes from mitochondrial injury and apoptosis under stress. The multifaceted effects of LLL on mitochondria bolstered megakaryocyte maturation; facilitated elongation, branching, and formation of proplatelets; and doubled the number of platelets generated from individual megakaryocytes in mice. LLL-mediated platelet biogenesis depended on megakaryopoiesis and was inversely correlated with platelet counts, which kept platelet biogenesis in check and effectively averted thrombosis even after repeated uses, in sharp contrast to all current agents that stimulate the differentiation of megakaryocyte progenitors from hematopoietic stem cells independently of platelet counts. This safe, drug-free, donor-independent modality represents a paradigm shift in the prophylaxis and treatment of thrombocytopenia. PMID:27464749

  12. Slovenia: Health System Review.

    Science.gov (United States)

    Albreht, Tit; Pribakovic Brinovec, Radivoje; Josar, Dusan; Poldrugovac, Mircha; Kostnapfel, Tatja; Zaletel, Metka; Panteli, Dimitra; Maresso, Anna

    2016-06-01

    This analysis of the Slovene health system reviews recent developments in organization and governance, health financing, health care provision, health reforms and health system performance. The health of the population has improved over the last few decades. While life expectancy for both men and women is similar to EU averages, morbidity and mortality data show persistent disparities between regions, and mortality from external causes is particularly high. Satisfaction with health care delivery is high, but recently waiting times for some outpatient specialist services have increased. Greater focus on preventive measures is also needed as well as better care coordination, particularly for those with chronic conditions. Despite having relatively high levels of co-payments for many services covered by the universal compulsory health insurance system, these expenses are counterbalanced by voluntary health insurance, which covers 95% of the population liable for co-payments. However, Slovenia is somewhat unique among social health insurance countries in that it relies almost exclusively on payroll contributions to fund its compulsory health insurance system. This makes health sector revenues very susceptible to economic and labour market fluctuations. A future challenge will be to diversify the resource base for health system funding and thus bolster sustainability in the longer term, while preserving service delivery and quality of care. Given changing demographics and morbidity patterns, further challenges include restructuring the funding and provision of long-term care and enhancing health system efficiency through reform of purchasing and provider-payment systems. PMID:27467813

  13. Treatment and recycling of spent nuclear fuel. Actinide partitioning - Application to waste management

    International Nuclear Information System (INIS)

    subsequent to its in-reactor dwell time, spent fuel still contains large amounts of materials that are recoverable, for value-added energy purposes (uranium, plutonium), together with fission products, and minor actinides, making up the residues from nuclear reactions. The treatment and recycling of spent nuclear fuel, as implemented in France, entail that such materials be chemically partitioned. The development of the process involved, and its deployment on an industrial scale stand as a high achievement of French science, and technology. Treatment and recycling allow both a satisfactory management of nuclear waste to be implemented, and substantial savings, in terms of fissile material. Bolstered of late as it has been, due to spectacularly skyrocketing uranium prices, this strategy is bound to become indispensable, with the advent of the next generation of fast reactors. This Monograph surveys the chemical process used for spent fuel treatment, and its variants, both current, and future. It outlines currently ongoing investigations, setting out the challenges involved, and recent results obtained by CEA. (authors)

  14. Treatment and recycling of spent nuclear fuel. Actinide partitioning - Application to waste management

    Energy Technology Data Exchange (ETDEWEB)

    Abonneau, E.; Baron, P.; Berthon, C.; Berthon, L.; Beziat, A.; Bisel, I.; Bonin, L.; Bosse, E.; Boullis, B.; Broudic, J.C.; Charbonnel, M.C.; Chauvin, N.; Den Auwer, C.; Dinh, B.; Duhamet, J.; Escleine, J.M.; Grandjean, S.; Guilbaud, P.; Guillaneux, D.; Guillaumont, D.; Hill, C.; Lacquement, J.; Masson, M.; Miguirditchian, M.; Moisy, P.; Pelletier, M.; Ravenet, A.; Rostaing, C.; Royet, V.; Ruas, A.; Simoni, E.; Sorel, C.; Vaudano, A.; Venault, L.; Warin, D.; Zaetta, A.; Pradel, P.; Bonin, B.; Bouquin, B.; Dozol, M.; Lecomte, M.; Forestier, A.; Beauvy, M.; Berthoud, G.; Defranceschi, M.; Ducros, G.; Guerin, Y.; Latge, C.; Limoge, Y.; Madic, C.; Santarini, G.; Seiler, J.M.; Sollogoob, P.; Vernaz, E.; Bazile, F.; Parisot, J.P.; Finot, P.; Roberts, J.F

    2008-07-01

    subsequent to its in-reactor dwell time, spent fuel still contains large amounts of materials that are recoverable, for value-added energy purposes (uranium, plutonium), together with fission products, and minor actinides, making up the residues from nuclear reactions. The treatment and recycling of spent nuclear fuel, as implemented in France, entail that such materials be chemically partitioned. The development of the process involved, and its deployment on an industrial scale stand as a high achievement of French science, and technology. Treatment and recycling allow both a satisfactory management of nuclear waste to be implemented, and substantial savings, in terms of fissile material. Bolstered of late as it has been, due to spectacularly skyrocketing uranium prices, this strategy is bound to become indispensable, with the advent of the next generation of fast reactors. This Monograph surveys the chemical process used for spent fuel treatment, and its variants, both current, and future. It outlines currently ongoing investigations, setting out the challenges involved, and recent results obtained by CEA. (authors)

  15. 西方制造商售后服务战略研究述评%A Literature Review on After-Sales Strategies for Manufacturers in Western Countries

    Institute of Scientific and Technical Information of China (English)

    张辉

    2012-01-01

    Integrating literatures in marketing management,operation management,and logistics,this paper reviews and discusses the driving forces of an after-sales strategy,after-sales service portfolios design,pricing and distributing after-sales services and corresponding organizational changes bolstering the strategy,in hope that it can guide the manufacturers in China to formulate and implement the strategy.Last,this paper also illuminates the paths leading to future research.%综合营销管理、运营管理和物流管理等多个学科的研究成果,从售后服务战略的动因,售后服务组合设计、定价、渠道、制造商组织变革几个方面对西方现有研究成果进行了回顾和评述,以期对我国制造商售后服务战略的制定与实施有所启示。最后,还对未来研究进行了展望。

  16. Financial Bubbles, Real Estate Bubbles, Derivative Bubbles, and the Financial and Economic Crisis

    Science.gov (United States)

    Sornette, Didier; Woodard, Ryan

    The financial crisis of 2008, which started with an initially well-defined epicenter focused on mortgage backed securities (MBS), has been cascading into a global economic recession, whose increasing severity and uncertain duration has led and is continuing to lead to massive losses and damage for billions of people. Heavy central bank interventions and government spending programs have been launched worldwide and especially in the USA and Europe, with the hope to unfreeze credit and bolster consumption. Here, we present evidence and articulate a general framework that allows one to diagnose the fundamental cause of the unfolding financial and economic crisis: the accumulation of several bubbles and their interplay and mutual reinforcement have led to an illusion of a "perpetual money machine" allowing financial institutions to extract wealth from an unsustainable artificial process. Taking stock of this diagnostic, we conclude that many of the interventions to address the so-called liquidity crisis and to encourage more consumption are ill-advised and even dangerous, given that precautionary reserves were not accumulated in the "good times" but that huge liabilities were. The most "interesting" present times constitute unique opportunities but also great challenges, for which we offer a few recommendations.

  17. Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium.

    Science.gov (United States)

    Pyne, Michael E; Bruder, Mark R; Moo-Young, Murray; Chung, Duane A; Chou, C Perry

    2016-01-01

    Application of CRISPR-Cas9 systems has revolutionized genome editing across all domains of life. Here we report implementation of the heterologous Type II CRISPR-Cas9 system in Clostridium pasteurianum for markerless genome editing. Since 74% of species harbor CRISPR-Cas loci in Clostridium, we also explored the prospect of co-opting host-encoded CRISPR-Cas machinery for genome editing. Motivation for this work was bolstered from the observation that plasmids expressing heterologous cas9 result in poor transformation of Clostridium. To address this barrier and establish proof-of-concept, we focus on characterization and exploitation of the C. pasteurianum Type I-B CRISPR-Cas system. In silico spacer analysis and in vivo interference assays revealed three protospacer adjacent motif (PAM) sequences required for site-specific nucleolytic attack. Introduction of a synthetic CRISPR array and cpaAIR gene deletion template yielded an editing efficiency of 100%. In contrast, the heterologous Type II CRISPR-Cas9 system generated only 25% of the total yield of edited cells, suggesting that native machinery provides a superior foundation for genome editing by precluding expression of cas9 in trans. To broaden our approach, we also identified putative PAM sequences in three key species of Clostridium. This is the first report of genome editing through harnessing native CRISPR-Cas machinery in Clostridium. PMID:27157668

  18. Management for Mountain Pine Beetle Outbreak Suppression: Does Relevant Science Support Current Policy?

    Directory of Open Access Journals (Sweden)

    Diana L. Six

    2014-01-01

    Full Text Available While the use of timber harvests is generally accepted as an effective approach to controlling bark beetles during outbreaks, in reality there has been a dearth of monitoring to assess outcomes, and failures are often not reported. Additionally, few studies have focused on how these treatments affect forest structure and function over the long term, or our forests’ ability to adapt to climate change. Despite this, there is a widespread belief in the policy arena that timber harvesting is an effective and necessary tool to address beetle infestations. That belief has led to numerous proposals for, and enactment of, significant changes in federal environmental laws to encourage more timber harvests for beetle control. In this review, we use mountain pine beetle as an exemplar to critically evaluate the state of science behind the use of timber harvest treatments for bark beetle suppression during outbreaks. It is our hope that this review will stimulate research to fill important gaps and to help guide the development of policy and management firmly based in science, and thus, more likely to aid in forest conservation, reduce financial waste, and bolster public trust in public agency decision-making and practice.

  19. The future of psychiatry as clinical neuroscience.

    Science.gov (United States)

    Reynolds, Charles F; Lewis, David A; Detre, Thomas; Schatzberg, Alan F; Kupfer, David J

    2009-04-01

    Psychiatry includes the assessment, treatment, and prevention of complex brain disorders, such as depression, bipolar disorder, anxiety disorders, schizophrenia, developmental disorders (e.g., autism), and neurodegenerative disorders (e.g., Alzheimer dementia). Its core mission is to prevent and alleviate the distress and impairment caused by these disorders, which account for a substantial part of the global burden of illness-related disability. Psychiatry is grounded in clinical neuroscience. Its core mission, now and in the future, is best served within this context because advances in assessment, treatment, and prevention of brain disorders are likely to originate from studies of etiology and pathophysiology based in clinical and translational neuroscience. To ensure its broad public health relevance in the future, psychiatry must also bridge science and service, ensuring that those who need the benefits of its science are also its beneficiaries. To do so effectively, psychiatry as clinical neuroscience must strengthen its partnerships with the disciplines of public health (including epidemiology), community and behavioral health science, and health economics.The authors present a Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis of psychiatry and identify strategies for strengthening its future and increasing its relevance to public health and the rest of medicine. These strategies encompass new approaches to strengthening the relationship between psychiatry and neurology, financing psychiatry's mission, emphasizing early and sustained multidisciplinary training (research and clinical), bolstering the academic infrastructure, and reorganizing and refinancing mental health services both for preventive intervention and cost-effective chronic disease management. PMID:19318776

  20. Coherent state description of non-topological solitons and momentum projection

    International Nuclear Information System (INIS)

    The solitons we are studing are localized, static solutions to classical (or semiclassical) non-linear field equations. Being localized, they do not correspond to momentum eigenstates, even though the field theories we are trying to solve are translationally invariant. In order to construct states of good momentum we need an explicity quantum wave function and not just expectation values of the fields (which are all we can get from a semiclassical treatment). The techniques discussed provide a wave function which embodies many of the features of the semiclassical (or mean field) approximation. This wave function can be projected onto states of definite momentum and hence can be used to calculate center-of-mass corrections to soliton properties. Many of the ideas involved have been around since the early days of quantum field theory but they have received little application apart from work by Bolsterli and Parmentola. The specific model to which we apply these methods is the soliton bag model of Friedberg and Lee. This is a model for the low energy properties of QCD in which hadrons appear as solitons in a scalar field with quarks trapped inside them. 27 references

  1. Exploratory study of the feasibility and utility of the colored eco-genetic relationship map (CEGRM) in women at high genetic risk of developing breast cancer.

    Science.gov (United States)

    Peters, June A; Kenen, Regina; Giusti, Ruthann; Loud, Jennifer; Weissman, Nancy; Greene, Mark H

    2004-10-15

    We report here the results of an exploratory feasibility study of the colored eco-genetic relationship map (CEGRM), a novel, recently-developed psychosocial assessment tool, which incorporates features of the genetic pedigree, family systems genogram, and ecomap. The CEGRM presents a simple, concise, visual representation of the social interaction domains of information, services, and emotional support through the application of color-coded symbols to the genetic pedigree. The interactive process of completing the CEGRM was designed to facilitate contemporary genetic counseling goals of: (a) understanding the client in the context of her/his social milieu; (b) bolstering client self-awareness and insight; (c) fostering active client participation and mutuality in the counseling interaction; (d) eliciting illuminating social narratives; and (e) addressing outstanding emotional issues. Twenty women participating in a breast imaging study of women from families with BRCA1/2 mutations completed and evaluated various aspects of the CEGRM. We found that efficient construction of the CEGRM was feasible, and that compliance was excellent. Participants developed insights into their social milieu through observing the visual pattern of relationships illustrated by the CEGRM. The process of co-constructing the CEGRM fostered the participant's active involvement in the session, marked by mutuality and increased empathy. In this clinical research context, the participants felt free to share poignant stories about their friends and families. Further studies are planned to refine the CEGRM and to examine its utility in cancer genetics research. PMID:15378540

  2. A Revised Method of Presenting Wavenumber-Frequency Power Spectrum Diagrams That Reveals the Asymmetric Nature of Tropical Large-scale Waves

    Science.gov (United States)

    Chao, Winston C.; Yang, Bo; Fu, Xiouhua

    2007-01-01

    The popular method of presenting wavenumber-frequency power spectrum diagrams for studying tropical large-scale waves in the literature is shown to give an incomplete presentation of these waves. The so-called "convectively-coupled Kelvin (mixed Rossby-gravity) waves" are presented as existing only in the symmetric (antisymmetric) component of the diagrams. This is obviously not consistent with the published composite/regression studies of "convectively-coupled Kelvin waves," which illustrate the asymmetric nature of these waves. The cause of this inconsistency is revealed in this note and a revised method of presenting the power spectrum diagrams is proposed. When this revised method is used, "convectively-coupled Kelvin waves" do show anti-symmetric components, and "convectively-coupled mixed Rossby-gravity waves (also known as Yanai waves)" do show a hint of symmetric components. These results bolster a published proposal that these waves be called "chimeric Kelvin waves," "chimeric mixed Rossby-gravity waves," etc. This revised method of presenting power spectrum diagrams offers a more rigorous means of comparing the General Circulation Models (GCM) output with observations by calling attention to the capability of GCMs in correctly simulating the asymmetric characteristics of the equatorial waves.

  3. Testing Capital Asset Pricing Model: Empirical Evidences from Indian Equity Market

    Directory of Open Access Journals (Sweden)

    Kapil CHOUDHARY

    2010-11-01

    Full Text Available The present study examines the Capital Asset Pricing Model (CAPM for the Indian stock market using monthly stock returns from 278 companies of BSE 500 Index listed on the Bombay stock exchange for the period of January 1996 to December 2009. The findings of this study are not substantiating the theory’s basic result that higher risk (beta is associated with higher levels of return. The model does explain, however, excess returns and thus lends support to the linear structure of the CAPM equation. The theory’s prediction for the intercept is that it should equal zero and the slope should equal the excess returns on the market portfolio. The results of the study lead to negate the above hypotheses and offer evidence against the CAPM. The tests conducted to examine the nonlinearity of the relationship between return and betas bolster the hypothesis that the expected return-beta relationship is linear. Additionally, this study investigates whether the CAPM adequately captures all-important determinants of returns including the residual variance of stocks. The results exhibit that residual risk has no effect on the expected returns of portfolios.

  4. Defining Socially-Based Spatial Boundaries in the Region of Peel, Ontario, Canada

    Directory of Open Access Journals (Sweden)

    Newbold K Bruce

    2011-05-01

    Full Text Available Abstract Background The purpose of the project was to delineate a series of contiguous neighbourhood-based "Data Zones" within the Region of Peel (Ontario for the purpose of health data analysis and dissemination. Zones were to be built on Census Tracts (N = 205 and obey a series of requirements defined by the Region of Peel. This paper explores a method that combines statistical analysis with ground-truthing, consultation, and the use of a decision tree. Data Census Tract data for Peel were derived from the 2006 Canadian Census Master file. Methods Following correlation analysis to reduce the data set, Principal Component Analysis was applied to the data set to reduce the complexity and derive an index. The Getis-Ord Gi*statistic was then applied to look for statistically significant clusters of like Census Tracts. A detailed decision tree for the amalgamation of remaining zones and ground-truthing with Peel staff verified the resulting zones. Results A total of 15 Data Zones that are similar with respect to socioeconomic and sociodemographic attributes and that met criteria defined by Peel were derived for the region. Conclusion The approach used in this analysis, which was bolstered by a series of checks and balances throughout the process, gives statistical validity to the defined zones and resulted in a robust series of Data Zones for use by Peel Public Health. We conclude by offering insight into alternative uses of the methodology, and limitations.

  5. Numerical and experimental modeling of liquid metal thin film flows in a quasi-coplanar magentic field

    International Nuclear Information System (INIS)

    Liquid metal film protection of plasma-facing surfaces in fusion reactors is proposed in an effort to counter the adverse effects of high heat and particle fluxes from the burning plasma. Concerns still exist about establishing the required flow in presence of strong magnetic fields and plasma momentum flux typical of a reactor environment. In this work, the flow behavior of the film is examined under such conditions. Analysis of MHD equations as they apply to liquid metal flows with a free surface in the fully-developed limit was undertaken. Solution yields data for velocity profiles and uniform film heights vs key design parameters (channel size, magnetic field magnitude/orientation, channel slope, wall conductivity). These results are compared to previous models to determine accuracy of simplifying assumptions, in particular Hartmann averaging of films along rvec B. Effect of a plasma momentum flux on the thin films is also analyzed. The plasma momentum is strong enough in the cases examined to seriously upset the film, especially for lighter elements like Li. Ga performed much better and its possible use is bolstered by calculations. In an experiment in the MeGA-loop MHD facility, coplanar, wide film flow was found to be little affected by the magnetic field due to the elongated nature of the film. Both MHD drag and partial laminarization are observed, supporting the fully- developed film model predictions of the onset of MHD drag and duct flow estimations for flow laminarization

  6. Smart Growth and the Challenge of Nimby: Multifamily Dwellings and their Association with Single-Family House Selling Prices in Tallahasse, Florida, USA

    Directory of Open Access Journals (Sweden)

    Huston GIBSON

    2013-06-01

    Full Text Available Citizens protest development when they consider it undesirable. One type of development commonly perceived as undesirable by single-family home owners is proximate multifamily housing, often considered a cause of property devaluation. This study assesses multifamily housing, by typology, and its monetary association with proximate single-family housing prices. The research design is a cross-sectional study using multivariate regression. The unit of analysis is the detached single-family dwelling. The study population is a sample taken from all arms-length owner-occupied, primary residence, detached single-family property transactions recorded in Tallahassee-Leon County, Florida, USA, during 2008. The key findings show no statistically significant negative associations between multifamily housing and single-family property selling prices in the sample; in fact, the two were positively correlated. These findings address single-family homeowner concerns about proximate multifamily housing and should bolster the political feasibility of Smart Growth policy, which recommends denser urban infill.

  7. Biogas energy from family-sized digesters in Uganda: Critical factors and policy implications

    Energy Technology Data Exchange (ETDEWEB)

    Walekhwa, Peter N. [Department of Agricultural Economics and Agribusiness, Makerere University, P.O. Box 7062, Kampala (Uganda)], E-mail: Peter.Walekhwa@mv.slu.se; Mugisha, Johnny [Department of Agricultural Economics and Agribusiness, Makerere University, P.O. Box 7062, Kampala (Uganda); Drake, Lars [Swedish Chemicals Agency, P.O. Box 2, SE-172 13, Sundbyberg (Sweden)

    2009-07-15

    Dependence on fossil energy sources is increasingly becoming unsustainable due to ecological and environmental problems and rapid depletion. Biogas energy could augment these conventional energy sources but despite its advantages and favourable conditions for its production, biogas energy use in Uganda remains low due to technical, economic and socio-cultural impediments. Based on primary data on households in Central and Eastern Uganda and the use of logistic regression, this study analyses factors affecting the adoption of biogas energy in Uganda. The empirical results suggest that the probability of a household adopting biogas technology increases with decreasing age of head of household, increasing household income, increasing number of cattle owned, increasing household size, male head of household and increasing cost of traditional fuels. In contrast, the likelihood of adoption decreases with increasing remoteness of household location and increasing household land area. Policy options and recommendations including educational and awareness campaigns on biogas benefits and successes, the provision of financial and non-financial incentives to households and establishment of an institutional framework could bolster wider biogas energy acceptance in Uganda.

  8. Biogas energy from family-sized digesters in Uganda. Critical factors and policy implications

    Energy Technology Data Exchange (ETDEWEB)

    Walekhwa, Peter N.; Mugisha, Johnny [Department of Agricultural Economics and Agribusiness, Makerere University, P.O. Box 7062, Kampala (Uganda); Drake, Lars [Swedish Chemicals Agency, P.O. Box 2, SE-172 13, Sundbyberg (Sweden)

    2009-07-15

    Dependence on fossil energy sources is increasingly becoming unsustainable due to ecological and environmental problems and rapid depletion. Biogas energy could augment these conventional energy sources but despite its advantages and favourable conditions for its production, biogas energy use in Uganda remains low due to technical, economic and socio-cultural impediments. Based on primary data on households in Central and Eastern Uganda and the use of logistic regression, this study analyses factors affecting the adoption of biogas energy in Uganda. The empirical results suggest that the probability of a household adopting biogas technology increases with decreasing age of head of household, increasing household income, increasing number of cattle owned, increasing household size, male head of household and increasing cost of traditional fuels. In contrast, the likelihood of adoption decreases with increasing remoteness of household location and increasing household land area. Policy options and recommendations including educational and awareness campaigns on biogas benefits and successes, the provision of financial and non-financial incentives to households and establishment of an institutional framework could bolster wider biogas energy acceptance in Uganda. (author)

  9. DISCOVERY OF THE HOST CLUSTER FOR THE FUNDAMENTAL CEPHEID CALIBRATOR ZETA GEMINORUM

    International Nuclear Information System (INIS)

    New and existing CORAVEL, UBVJHKs , HST, HIP/Tycho, ARO, KPNO, and DAO observations imply that the fundamental Cepheid calibrator ζ Gem is a cluster member. The following parameters were inferred for ζ Gem from cluster membership and are tied to new spectral classifications (DAO) established for 26 nearby stars (e.g., HD53588/B7.5IV, HD54692/B9.5IV): EB–V = 0.02 ± 0.02, log τ = 7.85 ± 0.15, and d = 355 ± 15 pc. The mean distance to ζ Gem from cluster membership and six recent estimates (e.g., IRSB) is d=363±9(σx-bar )±26 (σ) pc. The results presented here support the color-excess and HST parallax derived for the Cepheid by Benedict et al. Forthcoming precise proper motions (DASCH) and Chandra/XMM-Newton observations of the broader field may be employed to identify cluster members, bolster the cluster's existence, and provide stronger constraints on the Cepheid's fundamental parameters.

  10. NEW EVIDENCE SUPPORTING CLUSTER MEMBERSHIP FOR THE KEYSTONE CALIBRATOR DELTA CEPHEI

    International Nuclear Information System (INIS)

    New and existing UBVJHKs , spectroscopic, NOMAD, Hubble Space Telescope, and revised Hipparcos observations are employed to determine properties for δ Cep and its host star cluster. The multi-faceted approach ensured that uncertainties were mitigated (σ/d ∼ 2%). The following fundamental parameters were inferred for δ Cep: E(B – V) = 0.073 ± 0.018(σ), log τ = 7.9 ± 0.1, and d=272 ± 3(σx-bar) ± 5 (σ) pc. The cluster exhibits a turnoff near B6 (M*/M☉ ∼ 5), and the brightest host cluster members are the supergiants ζ Cep (K1.5Ib) and δ Cep. To within the uncertainties, the two stars share common astrometric parameters (π, μα, μδ, RV ∼ –17 km s–1) and are tied to bluer members via the evolutionary track implied by the cluster's UBVJHKs color-color and color-magnitude diagrams. The cluster's existence is bolstered by the absence of an early-type sequence in color-magnitude diagrams for comparison fields. NOMAD data provided a means to identify potential cluster members (n ∼ 30) and double the existing sample. That number could increase with forthcoming precise proper motions (DASCH) for fainter main-sequence stars associated with classical Cepheids (e.g., δ Cep), which may invariably foster efforts to strengthen the Galactic Cepheid calibration and reduce uncertainties tied to H0.

  11. Shared Illness and Social Support Within Two HIV-Affected African American Communities.

    Science.gov (United States)

    Mosack, Katie E; Stevens, Patricia E; Brouwer, Amanda M; Wendorf, Angela R

    2016-09-01

    A key source of resiliency within HIV-affected African American communities is informal social support. Data from dyadic conversations and focus groups were used to address the following research question: What are HIV-positive African Americans' social support experiences within their informal social networks in response to HIV-related problems? Circumstances that exacerbated HIV-related problems included others' fear of contagion, reticence to be involved, judgment and rejection, and disregard for privacy Support from HIV-negative others buffered the impact of problems when others communicate interest, take the initiative to help, or make a long-term investment in their success. Support from other HIV-positive persons was helpful given the shared connection because of HIV, the opportunity to commiserate about what is mutually understood, and the fight for mutual survival Based on these findings, we offer suggestions for future research and social network interventions aimed at bolstering connections between HIV-positive peers, reducing stigma, and improving family support. PMID:26515921

  12. Stages of Colonialism in Africa: From Occupation of Land to Occupation of Being

    Directory of Open Access Journals (Sweden)

    Hussein A. Bulhan

    2015-08-01

    Full Text Available This paper draws primarily on my own scholarship, supplemented by the limited academic resources available in the “peripheries” of the world where I live and work (namely, Somali society and Darfur, Sudan, to consider the relationship between colonialism and psychology. I first consider the history of psychology in justifying and bolstering oppression and colonialism. I then consider the ongoing intersection of colonialism and psychology in the form of metacolonialism (or coloniality. I end with thoughts about decolonizing psychological science in teaching, social, and clinical practice. To decolonize psychological science, it is necessary to transform its focus from promotion of individual happiness to cultivation of collective well-being, from a concern with instinct to promotion of human needs, from prescriptions for adjustment to affordances for empowerment, from treatment of passive victims to creation of self-determining actors, and from globalizing, top-down approaches to context-sensitive, bottom-up approaches. Only then will the field realize its potential to advance Frantz Fanon’s call for humane and just social order.

  13. The Dynamics of Brownfield Redevelopment

    Directory of Open Access Journals (Sweden)

    Mark Paich

    2011-06-01

    Full Text Available Negligence of former industrial sites (“brownfields” has adversely impacted urban landscapes throughout the industrialized world. Brownfield redevelopment has recently emerged as a sustainable land use strategy and impetus for urban revitalization. This study presents a system dynamics model of the redevelopment process that illustrates how delays compound before realizing financial benefits from investment in these core urban areas. We construct a dynamic hypothesis, in which brownfield redevelopment activities are dependent upon funding and in turn bolster tax base through job creation. Drawing on previous studies, barriers to brownfield redevelopment are explored, including fear of liability, regulatory concerns, and uncertain cleanup standards and funding mechanisms. We model a case study of redevelopment in the State of Michigan (USA, which is informed by data from the Department of Environmental Quality (MDEQ and U.S. Conference of Mayors brownfield surveys. Stock-flow structures represent phases of redevelopment, with diverted streams for sites in which no contamination was found (false alarms and those with excess contamination level. The model is used to examine the point at which cumulative tax revenues from redeveloped areas exceed cumulative expenditures on brownfield redevelopment under different levels of funding availability.

  14. Worldwide Engagement for Sustainable Energy Strategies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-01

    Almost 40 years after the Agency’s founding, the IEA responsibility for ensuring access to global oil supplies is still a core mandate. Yet over the course of its history, the IEA’s responsibilities have expanded along with both the international energy economy and conceptions of energy security itself. Our mission to promote secure and sustainable energy provision spans the energy mix. At the same time, a changing global energy map means that the industrialised nations of the world no longer dominate energy consumption. The IEA must work in close co-operation with partner countries and organisations worldwide to achieve its three core objectives: energy security, economic prosperity, and environmental sustainability. Working toward international commitments to reduce greenhouse gas emissions that cause global climate change; facilitating energy technology exchange, innovation and deployment; improving modern energy access to the billions of people who are without it; bolstering both cleanliness and security through energy efficiency; and promoting flexible and functioning energy markets – these efforts complement our traditional core responsibilities of mitigating the effects of supply disruptions and improving statistical transparency.

  15. The Yeast Retrograde Response as a Model of Intracellular Signaling of Mitochondrial Dysfunction

    Directory of Open Access Journals (Sweden)

    S. Michal eJazwinski

    2012-05-01

    Full Text Available Mitochondrial dysfunction activates intracellular signaling pathways that impact yeast longevity, and the best known of these pathways is the retrograde response. More recently, similar responses have been discerned in other systems, from invertebrates to human cells. However, the identity of the signal transducers is either unknown or apparently diverse, contrasting with the well-established signaling module of the yeast retrograde response. On the other hand, it has become equally clear that several other pathways and processes interact with the retrograde response, embedding it in a network responsive to a variety of cellular states. An examination of this network supports the notion that the master regulator NFkB aggregated a variety of mitochondria-related cellular responses at some point in evolution and has become the retrograde transcription factor. This has significant consequences for how we view some of the deficits associated with aging, such as inflammation. The support for NFkB as the retrograde response transcription factor is not only based on functional analyses. It is bolstered by the fact that NFkB can regulate Myc-Max, which is activated in human cells with dysfunctional mitochondria and impacts cellular metabolism. Myc-Max is homologous to the yeast retrograde response transcription factor Rtg1-Rtg3. Further research will be needed to disentangle the pro-aging from the anti-aging effects of NFkB. Interestingly, this is also a challenge for the complete understanding of the yeast retrograde response.

  16. The Energy Box

    Energy Technology Data Exchange (ETDEWEB)

    Friedmann, S J; Homer-Dixon, T

    2004-07-12

    Only Nixon could go to China. And maybe only petroleum industry CEOs can spur action on global climate change. Here's Lord Browne, head of BP, in a recent issue of Foreign Affairs magazine: 'Global temperatures have risen by about 0.6 degrees Celsius since the nineteenth century. Other measures of climate bolster the theory that the world is getting warmer. . . . [The] trend is undoubtedly due in large part to substantial increases in carbon dioxide (CO2) emissions from human activity.' But should we do something about this trend? Browne is unequivocal. In a speech to the Council on Foreign Relations at about the same time his article appeared, he declared: 'It would be too great a risk to stand by, do nothing, and to wait so long that when the impact on the climate really does begin to be felt, you have to take action which is so disruptive as to cause serious damage to the world's economy. There is a very strong case for precautionary action.'

  17. Objections, confusion among pharmacists threaten access to emergency contraception.

    Science.gov (United States)

    Cohen, S A

    1999-06-01

    Emergency contraception (EC) involves women taking a high dose of regular oral contraceptives very shortly after unprotected intercourse. Specifically, emergency contraceptive pills (ECPs) can prevent pregnancy if taken within 72 hours of intercourse in cases of known or suspected contraception failure or when no contraception was used. Adherence to this approach is now widely accepted as capable of dramatically contributing toward the reduction of unintended pregnancies and subsequent abortions. However, in the media and in political debates, ECPs are often confused with mifepristone (RU-486), which is clearly an abortion-inducing drug. The misconception that EC is a method of abortion must be corrected. For example, in some cases, pharmacists refuse to fill prescriptions for ECPs, presumably because they believe they are facilitating abortion. Wal-Mart, one of the country's largest drug retailers, has decided to not sell ECPs. A concerted public education effort is needed to make more people both aware and properly informed of EC in the US. Educational efforts targeted to physicians and women over the past several years appear to have already resulted in a marked increase in the knowledge and use of EC nationwide. Those efforts were likely bolstered by the 1998 US Food and Drug Administration approval, for the first time, of an oral contraception regimen to be packaged and marketed in the US specifically for postcoital use. PMID:12295186

  18. Highly sensitive tube-topology magnetoelectric magnetic sensors

    Science.gov (United States)

    Gillette, Scott Matthew

    Magnetoelectric (ME) composites have drawn increasing interest in recent years due to advancements in the technology resulting in enhanced ME coupling coefficients, stable room-temperature operation, sub-nanoTesla noise floor, low- and zero-biased operation, and fabrication of compact, miniaturized devices. Now, more than ever, practical use of ME devices in commercial magnetometry applications is feasible, while continued development of numerous other applications, such as voltage-tunable magnetic field generators, voltage-tunable inductors, and magnetically-tunable capacitors, bolster the overall usefulness of ME composites as a valuable technology. This dissertation focuses on development and characterization of tube-topology ME composites as magnetic field sensors. The novel topology is most notable for demonstrating high zero-external-bias sensitivity, low noise floor, low-frequency bandwidth, and self-powered, stable room temperature operation. Numerous characterization studies are included in this work where several devices are analyzed as a function of test-field, DC-bias field, geometry, material choice, and more. The overall conclusions drawn upon these results indicate strongly that the tube-topology ME magnetic field sensor holds promise to compete with existing hall-effect and flux-gate magnetometers. ME composites are at the tipping point of commercialization for use in magnetometry applications and are emerging as a valuable technology for use in numerous creative ways.

  19. Influence of ethnocentrism and neo-phobia on ethnic food consumption in Spain.

    Science.gov (United States)

    Camarena, Dena M; Sanjuán, Ana I; Philippidis, George

    2011-08-01

    Over the last decade, a strong upsurge in Spanish immigration has fostered a thriving ethnic food market. To examine indigenous consumer predilections toward ethnic foods, a carefully designed choice experiment is employed, with particular focus on ethnocentricity and food neo-phobia traits on potential purchase decisions. Employing a two level nested logit model, consumers choose to accept/reject ethnic foods, with a positive response met by a further series of different ethnic cuisine and consumption scenario alternatives. Bivariate tests reveal that higher ethnocentric and neo-phobic segments possess common socio-demographic characteristics, whilst neo-phobia plays a significantly stronger role in determining the probability of rejection. Further tests reveal culturally similar Mexican food as the preferred ethnic food across all consumption scenarios. Moreover, the 'restaurant' is the favoured format of consumption, whilst there is evidence of a strong association between specific ethnic food types and consumption formats. The implications of our research suggest that in the short to medium turn, price is a strong strategic variable, whilst marketing strategies must successfully isolate and exploit specific 'ethnic food/consumption scenario' mixes. Finally, stronger messages emphasizing quality and convenience factors are seen as key to bolstering the underrepresented 'home preparation' ethnic food market in Spain. PMID:21513751

  20. REVERBERATION MAPPING OF A LOW-MASS BLACK HOLE IN A NARROW-LINE SEYFERT 1 GALAXY

    International Nuclear Information System (INIS)

    We present results of a reverberation mapping (RM) campaign on the low black hole mass narrow-line Seyfert 1 (NLS1) galaxy SDSS J113913.91+335551.1 (hereafter SL01). Using the Hβ measurements, we find a time lag τ= 12.5+0.5-11 days and a broad-line velocity width of 1450 km s–1 which implies a black hole mass of 3.8+0.6-2.8×106 M☉. To further bolster our time lag results, we employ a secondary method based on the multivariate correlation function as described in Chelouche and Zucker, in which case we obtain consistent lags for the Balmer lines, yet without the need to spectrally deconvolve line from continuum emission processes. Given SL01's luminosity (Lbol ≈ 7 × 1043 erg s–1), we estimate an Eddington ratio (Lbol/LEdd) of ∼0.18. This fairly low-mass determination and rather high Lbol/LEdd is consistent with the current paradigm that the nuclei of NLS1 galaxies host small black holes (as low as 106 M☉) with high accretion rates. SL01 is one of only a few NLS1s to date with robust RM results

  1. Golden Jubilee Photos: Four giants break new ground

    CERN Multimedia

    2004-01-01

    The four LHC experiments are on an unprecedented scale. The detectors will record particle collisions far more powerful than those at any other particle accelerator. One of the detectors, ATLAS, will be the largest-volume particle detector ever, a cylinder 45 metres long and 25 metres high. And the collaborations are a step beyond LHC's predecessor, LEP, involving even more people from more countries. Together, these four experiments promise to open a door to new realms of physics. CMS and ATLAS are both general-purpose detectors, whose major quarry include the Higgs particle, which could give other particles their mass, and supersymmetric particles, which would bolster theories beyond the Standard Model. A major technical challenge for CMS has been acquiring 61 000 large, precision-grown crystals, denser than iron, for catching high-energy photons and electrons (1st bottom photo). ATLAS includes the world's largest superconducting magnets (2nd bottom photo), eight coils arranged into a large barrel shape t...

  2. TOPICAL REVIEW: Stem cells engineering for cell-based therapy

    Science.gov (United States)

    Taupin, Philippe

    2007-09-01

    Stem cells carry the promise to cure a broad range of diseases and injuries, from diabetes, heart and muscular diseases, to neurological diseases, disorders and injuries. Significant progresses have been made in stem cell research over the past decade; the derivation of embryonic stem cells (ESCs) from human tissues, the development of cloning technology by somatic cell nuclear transfer (SCNT) and the confirmation that neurogenesis occurs in the adult mammalian brain and that neural stem cells (NSCs) reside in the adult central nervous system (CNS), including that of humans. Despite these advances, there may be decades before stem cell research will translate into therapy. Stem cell research is also subject to ethical and political debates, controversies and legislation, which slow its progress. Cell engineering has proven successful in bringing genetic research to therapy. In this review, I will review, in two examples, how investigators are applying cell engineering to stem cell biology to circumvent stem cells' ethical and political constraints and bolster stem cell research and therapy.

  3. Polyacrylamide Gel-Entrapped Fungal Manganese Peroxidase from Ganoderma lucidum IBL-05 with Enhanced Catalytic, Stability, and Reusability Characteristics.

    Science.gov (United States)

    Bilal, Muhammad; Asgher, Muhammad; Iqbal, Hafiz M N

    2016-01-01

    In the present study, polyacrylamide gel (PAG) was utilized as bolster material for the immobilization of in-house extracted and partially purified manganese peroxidase (MnP) through an entrapment technique yielding significant MnP immobilization (87.3±3.3 %) and remarkable stability of the enzyme (37.2±2.4 %) after a storage period of two months at 4°C. The immobilization also increased the optimal temperature by 10 °C and provided an alkaline shift of the pH optimum. Moreover, a significant enhancement in the thermo-stability was observed. After an incubation period of 72 h at 50°C, the PAG-entrapped-MnP still exhibited 41.2 % of the initial activity, whereas the free enzyme was completely inactive. Furthermore, PAG-entrapped-MnP showed an excellent recycling efficiency and retained more than 50% of its initial activity after five consecutive reaction cycles. In conclusion, owing to the economic feasibility, carrier-supported MnP may be a promising candidate for various applications in different industrial sectors. PMID:27531237

  4. European Community in new international petroleum order

    International Nuclear Information System (INIS)

    This paper examines the chances that the European Community (EC) has of enhancing its position in the international petroleum order. Its identity should become stronger than it is in the current feeble state of Europe as a world presence for four reasons: greater convergence in the ideas and interests of the Member Countries; the bolstering of Community institutions; thanks to new treaties, more balanced petro-political relations; and the geographical advantage of being within reach of Russia's enormous hydrocarbon resources. In its producer-consumer relations, the EC has a certain amount of upfront legitimacy over the actions of the individual member countries, insofar as multilateral actions in this field are more efficient than are bilateral relations. The EC is acquiring a certain autonomy of action from the AIH. It is already helping to build up new relations through informal dialogue and free-trade agreements with the producing countries, and is helping Russia to emerge as a major competitor for the Gulf countries

  5. Comparing the health and social protection effects of measles vaccination strategies in Ethiopia: An extended cost-effectiveness analysis.

    Science.gov (United States)

    Driessen, Julia; Olson, Zachary D; Jamison, Dean T; Verguet, Stéphane

    2015-08-01

    Vaccination coverage rates often mask wide variation in access, uptake, and cost of providing vaccination. Financial incentives have been effective at creating demand for social services in a variety of settings. Using methods of extended cost-effectiveness analysis, we compare the health and economic implications of three different vaccine delivery strategies for measles vaccination in Ethiopia: i) routine immunization, ii) routine immunization with financial incentives, and iii) mass campaigns, known as supplemental immunization activities (SIAs). We examine annual birth cohorts of almost 3,000,000 births over a ten year period, exploring variation in these outcomes based on economic status to understand how various options may improve equity. SIAs naturally achieve higher levels of vaccine coverage, but at higher costs. Routine immunization combined with financial incentives bolsters demand among more economically vulnerable households. The relative appeal of routine immunization with financial incentives and SIAs will depend on the policy environment, including short-term financial limitations, time horizons, and the types of outcomes that are desired. While the impact of financial incentives has been more thoroughly studied in other policy arenas, such as education, consideration of this approach alongside standard vaccination models such as SIAs is timely given the dialog around measles eradication. PMID:26189009

  6. Biofidelity Evaluation of a Prototype Hybrid III 6 Year-Old ATD Lower Extremity.

    Science.gov (United States)

    Boucher, Laura C; Bing, Julie; Bolte, John H

    2016-09-01

    Incomplete instrumentation and a lack of biofidelity in the extremities of the 6 year-old anthropomorphic test device (ATD) pose challenges when studying regions of the body known to interact with the vehicle interior. This study sought to compare a prototype Hybrid III 6 year-old ATD leg (ATD-LE), with a more biofidelic ankle and tibia load cell, to previously collected child volunteer data and to the current Hybrid III 6 year-old ATD (HIII). Anthropometry, range of motion (ROM), and stiffness measurements were taken, along with a dynamic evaluation of the ATD-LE using knee-bolster airbag (KBA) test scenarios. Anthropometry values were similar in eight of twelve measurements. Total ankle ROM was improved in the ATD-LE with no bumper compared to the HIII. The highest tibia moments and tibia index values were recorded in KBA scenarios when the toes were positioned in contact with the dashboard prior to airbag deployment, forcing the ankle into axial loading and dorsiflexion. While improvements in the biofidelity of the ATD-LE are still necessary, the results of this study are encouraging. Continued advancement of the 6 year-old ATD ankle is necessary to provide a tool to directly study the behavior of the leg during a motor vehicle crash. PMID:26864538

  7. Surface-sensitive two-dimensional magneto-fingerprint in mesoscopic Bi2Se3 channels.

    Science.gov (United States)

    Kandala, Abhinav; Richardella, Anthony; Zhang, Duming; Flanagan, Thomas C; Samarth, Nitin

    2013-06-12

    Periodic Aharonov–Bohm and Altshuler–Aronov–Spivak oscillations have traditionally been observed in lateral transport through patterned mesoscopic loops of diffusive conductors. However, our studies of perpendicular-to-plane magnetotransport in straight-channel, diffusive devices of epitaxial Bi2Se3 surprisingly reveal signatures of Aharonov–Bohm orbits, periodic conductance fluctuation magneto-fingerprints, even though the devices are not explicitly patterned into loops. We show that the length scale of these orbits corresponds to the typical perimeter of triangular terraces found on the surface of these thin film devices, strongly suggesting that the periodic magneto-fingerprint arises from coherent scattering of electron waves from the step-edges. Our interpretation is bolstered by control measurements in devices without such surface morphology that only show a conventional, aperiodic magneto-fingerprint. These results show that lithographically patterned Bi2Se3 devices provide a novel class of mesoscopic physical systems for systematic studies of coherent surface sensitive transport. PMID:23642037

  8. The study on key performance indices in national nuclear R and D program

    International Nuclear Information System (INIS)

    Korean government has increased its investment of national research and development (R and D) recognizing that science and technology is a core element to bolster national economy and upgrade human life. In addition, measures have been developed to evaluate the R and D performance and contribution as they become critical and play pivotal roles to allocate national R and D budget in order to prevent the spillover effects. The nuclear technology development program is the backbone of the nuclear R and D programs in Korea. Since the nuclear R and D requires not only massive human resources and capitals but huge research equipment and facilities, the nuclear related science technology field is usually led by the government because of the high possibility of risk, failure or rewards, the necessity of huge budget, and the research spin off. The MEST (Ministry of Education and Science Technology) lays the groundwork for the advancement in nuclear R and D and the development of highly advanced technology by securing core technology. In addition, it also fosters world leading scientists with a creative research environment and an efficient R and D infrastructure. The main purpose of the study is to develop the logic model and design key performance indices for nuclear R and D program. The brief review of basic framework and contents for the performance evaluation system was explained in section 2. Based on the suggested evaluation framework, logic model and key performance indices are provided in section 3 and finally, concluding remarks are given in section 4

  9. Computational biology and bioinformatics in Nigeria.

    Directory of Open Access Journals (Sweden)

    Segun A Fatumo

    2014-04-01

    Full Text Available Over the past few decades, major advances in the field of molecular biology, coupled with advances in genomic technologies, have led to an explosive growth in the biological data generated by the scientific community. The critical need to process and analyze such a deluge of data and turn it into useful knowledge has caused bioinformatics to gain prominence and importance. Bioinformatics is an interdisciplinary research area that applies techniques, methodologies, and tools in computer and information science to solve biological problems. In Nigeria, bioinformatics has recently played a vital role in the advancement of biological sciences. As a developing country, the importance of bioinformatics is rapidly gaining acceptance, and bioinformatics groups comprised of biologists, computer scientists, and computer engineers are being constituted at Nigerian universities and research institutes. In this article, we present an overview of bioinformatics education and research in Nigeria. We also discuss professional societies and academic and research institutions that play central roles in advancing the discipline in Nigeria. Finally, we propose strategies that can bolster bioinformatics education and support from policy makers in Nigeria, with potential positive implications for other developing countries.

  10. Modelling the extreme precipitation event over Madeira Island on 20 February 2010

    Directory of Open Access Journals (Sweden)

    T. Luna

    2011-09-01

    Full Text Available In the morning of the 20 February of 2010 an extreme precipitation event occurred over Madeira Island. This event triggered several flash floods and mudslides in the southern parts of the island, resulting in 42 confirmed deaths, 100 injured, and at least 8 people still missing. These extreme weather conditions were associated to a weather frontal system moving northeastwards embedded in a low pressure area centered in the Azores archipelago. This storm was one in a series of such storms that affected Portugal, Spain, Morocco and the Canary islands causing flooding and strong winds. These storms were bolstered by an unusually strong sea surface temperature gradient across the Atlantic Ocean.

    In this study, the WRF model is used to evaluate the intensity and predictability of this precipitation extreme event over the island. The synoptic/orographic nature of the precipitation is also evaluated, as well as the sensitivity of the model to horizontal resolution and cumulus parameterization. Orography was found to be the main factor explaining the occurrence, amplitude and phase of precipitation over the Island.

  11. Competition in California: questions remain about the impact of deregulation on renewable energy

    International Nuclear Information System (INIS)

    After little more than a year of client choice in California's electricity market, it is still uncertain whether competition can create anything more than a niche market for the state's renewable energy industry. As of the end of May, only about 1.35% of California's eligible clients had switched their electricity provider. More than 92,000 of those switches were residential, representing roughly 1% of the state's households. While the total number of switches is small, an estimated 50% of all small clients who have switched have chosen renewables. Deregulation came with a $540 million fund to bolster renewable technologies. About 30% of that, or $162 million, is being used to subsidize 55 new wind, geothermal, landfill gas, biomass and small hydro projects totalling more than 500 MW, expected to come on stream over the next four years. The new competitive turn could have an impact on the kind of technologies that become the preferred providers over the long term. California's deregulation has been criticized as confusing and poorly constructed, leaving small clients with little incentive to change. A higher than expected demand for green power among commercial clients is one of the positive surprises of the California market. Twenty one percent of green power demand came from small commercial, industrial and agricultural clients

  12. Extension of an Exponential Light Curve GRB Pulse Model Across Energy Bands

    CERN Document Server

    Nemiroff, Robert J

    2011-01-01

    A simple mathematical model of GRB pulses in time, suggested in Norris et al. (2005), is extended across energy. For a class of isolated pulses, two of those parameters appear effectively independent of energy. Specifically, statistical fits indicate that pulse amplitude $A$ and pulse width $\\tau$ are energy dependent, while pulse start time and pulse shape are effectively energy independent. These results bolster the Pulse Start and Pulse Scale conjectures of Nemiroff (2000) and add a new Pulse Shape conjecture which states that a class of pulses all have the same shape. The simple resulting pulse counts model is $P(t,E) = A(E) \\ {\\rm exp} (-t/\\tau(E) - \\tau(E)/t)$, where $t$ is the time since the start of the pulse. This pulse model is found to be an acceptable statistical fit to many of the fluent separable BATSE pulses listed in Norris et al. (2005). Even without theoretical interpretation, this cross-energy extension may be immediately useful for fitting prompt emission from GRB pulses across energy chan...

  13. Leveraging the Experiences of Informal Caregivers to Create Future Healthcare Workforce Options.

    Science.gov (United States)

    Phillips, Sara S; Ragas, Daiva M; Hajjar, Nadia; Tom, Laura S; Dong, XinQi; Simon, Melissa A

    2016-01-01

    The objective of this study was gather pilot data from informal caregivers regarding the potential for a training program to assist current or past caregivers in reentering the job market, and thus offering a pathway to economic resilience. In an effort that could foster a sustainable and competent caregiving market to help meet the needs of an aging America, whether training informal caregivers might help them transition into a paid caregiving or other health service role was explored. Caregivers (N=55) of a chronically or terminally ill family member or friend in a suburban county near Chicago were interviewed. The interview guide addressed household economic effect of illness, emotional burden, and training program interest. Fifty-six percent of caregivers were interested in training to work outside the home, caring for people in other households, 84% indicated a desire to learn more about health care, and 68% reported a desire to explore job possibilities in health care. Eighty-two percent were experienced in working with an individual aged 50 and older. Informal caregivers' interest in a training program to bolster their qualifications for a role in the healthcare workforce, including the option of a formal caregiver position, supports the demand for such a program. Considering the need for healthcare workers to serve the growing elderly population and the desire of informal caregivers to find gainful employment, these informal caregivers could provide the impetus to invest in informal caregiver training. PMID:26782869

  14. Conductometric and volumetric studies of atorvastatin in aqueous solution of arginine from 298.15 to 313.15 K

    Directory of Open Access Journals (Sweden)

    M. M. R. Meor Mohd Affandi

    2016-01-01

    Full Text Available Categorized as a Biopharmaceutics Classification System Class II drugs, atorvastatin (ATV exhibits low aqueous solubility and bioavailability thus presenting an obstacle and great challenge to formulation researchers. Numerous studies are available in regard to the solubility enhancement of ATV, but very few actually describe this phenomenon in terms of thermodynamics and the solute-solvent interaction. Arginine (ARG is an amino acid that has been reported to enhance the solubility of the highly insoluble wheat protein gluten through hydrogen bonding and π electron-cation interaction. To our knowledge, ARG has never been investigated as a solubility enhancement agent of aqueous insoluble drugs. Thus, this study aimed to elucidate the solute-solvent and solute-cosolute interactions and derive thermodynamic parameters that bolstered the solubility of ATV in the presence of ARG. We examined the electrolytic conductance and densities of ATV-ARG binary system covering the temperature ranging from 298.15 K to 313.15 K. Conductometric and volumetric parameters such as limiting molar conductance, association constants, limiting partial molar volumes, and expansibility values were calculated. Additionally, thermodynamic parameters (ΔG0, ΔH0, ΔS0, and Es involved in the association process of the solute in the aqueous solution of ARG were also determined.

  15. Private Equity Capital in a Less Developed Economy: Evidence, Issues and Perspectives

    Directory of Open Access Journals (Sweden)

    Melusi Mpofu

    2015-10-01

    Full Text Available This study investigates the structure of the private equity industry and issues that impact on its development and growth in Zimbabwe. Studies conducted internationally have unequivocally demonstrated the importance of private equity investments in assisting firms at start/growth phase and decline phase. However there is a dearth of literature on how these financial intermediaries assist in unlocking firm value from an emerging markets perspective. The study uses the document analysis and an exploratory research paradigms to achieve the stated objectives. The study finds that the venture capital industry in Zimbabwe mimics similar industries in other countries except that it is constrained by market liquidity. Lack of regulation and viable business sectors coupled with excessive risks in the political economy narrows the scope of private equity operations. Several issues impacting on the development of the private equity industry are identified and evaluated. The study has policy implications for the development of regulatory framework to bolster the growth of the private equity industry in emerging market economies. This study provides new evidence and policy suggestions on the operations of the private equity industry in a liquidity constrained and less developed economy.

  16. No evidence for melatonin-linked immunoenhancement over the annual cycle of an avian species.

    Science.gov (United States)

    Buehler, Deborah M; Koolhaas, Anita; Van't Hof, Thomas J; Schwabl, Ingrid; Dekinga, Anne; Piersma, Theunis; Tieleman, B Irene

    2009-05-01

    The winter immunoenhancement hypothesis associates long nights and increased exposure to melatonin with enhanced immune function in winter when resource availability is low and the chances of becoming ill are high. Thus, increased exposure to melatonin in the winter could be adaptive for species facing difficult winter conditions. This idea has found some support in studies of resident mammals. In birds, the link between day length and melatonin over the annual cycle is weaker, and contributions of melatonin to seasonal timing are unclear. Furthermore, many species, especially migrants, do not experience the most difficult conditions of their annual cycle in winter. In this study, we tested whether the winter immunoenhancement hypothesis holds in an avian species, the red knot Calidris canutus. We found that melatonin duration and amplitude varied significantly over the annual cycle with the highest values occurring in winter. However, peaks did not correspond to the winter solstice or with annual variation in immune function. Our findings do not support the winter immunoenhancement hypothesis in knots and question whether the idea that immune function should be bolstered in winter can be generalized to systems where winter is not the most difficult time of the year. PMID:19234709

  17. Urbanization, housing and environment: Megacities of Africa

    Directory of Open Access Journals (Sweden)

    Olusola Oladapo Makinde

    2012-12-01

    Full Text Available This paper takes a look at urbanization, housing and environment in Africa megacities; it enumerates the problems caused by the continued influx of migrant into cities, and state the government, private and public organization effort in solving these challenges. It found out that with proper management, the chilling prospect of a serious deterioration in quality of life could be averted. The report noted that continuing migration from rural to urban areas will expand the number of megacities, and it concedes that megacities are often plagued by environmental deterioration, inadequate housing, traffic congestion, social alienation slums, crime and homelessness. Etc. The paper, observed that megacities are important to a country's economic development, and also provide residents with a satisfying quality of life, if properly managed. The report looked for ways of solving the problems to a significant degree and observed that nearly in all cases, the gaps between demand and supply are management related, and recommends ways of improving the quality of citizen life by provision of adequate and quality housing, reduction in land costs, healthy environment, clean water and sanitation services, security within the city, employment opportunity, bolstering urban farming, and improving public transportation and make sure that the megacities are beneficial to the environment as well as to the national economy. The paper admits that the solutions are far from easy. It is difficult to predict what will happen if there are shortfalls in the financing of megacity growth and management.

  18. The role of the neuro-astro-vascular unit in the etiology of Ataxia Telangiectasia

    Directory of Open Access Journals (Sweden)

    Leenoy eMeshulam

    2012-09-01

    Full Text Available The growing recognition that brain pathologies do not affect neurons only but rather are, to a large extent, pathologies of glial cells as well as of the vasculature opens to new perspectives in our understanding of genetic disorders of the CNS. To validate the role of the neuron-glial-vascular unit in the etiology of genome instability disorders, we report about cell death and morphological aspects of neuro-glia networks and the associated vasculature in a mouse model of Ataxia Telangiectasia (A-T, a human genetic disorder that induces severe motor impairment. We found that AT-mutated protein deficiency was consistent with aberrant astrocytic morphology and alterations of the vasculature, often accompanied by reactive gliosis. Interestingly similar findings could also be reported in the case of other genetic disorders. These observations bolster the notion that astrocyte-specific pathologies, hampered vascularization and astrocyte-endothelium interactions in the CNS could play a crucial role in the etiology of genome instability brain disorders and could underlie neurodegeneration.

  19. The Effects of Stigma on Recovery Attitudes in People With Anorexia Nervosa in Intensive Treatment.

    Science.gov (United States)

    Dimitropoulos, Gina; McCallum, Leslie; Colasanto, Marlena; Freeman, Victoria E; Gadalla, Tahany

    2016-05-01

    Self-stigma in individuals with anorexia nervosa (AN) may affect engagement in intensive treatment. The objective of this study was to test a Model of Self-Stigma to identify the influence of public stigma, internalized stigma, self-esteem, and self-efficacy on recovery attitudes in individuals in inpatient treatment for AN. Using a cross-sectional design, 36 female participants with AN completed questionnaires during the first week of intensive inpatient treatment. Better attitude towards recovery was positively correlated with higher self-esteem and self-efficacy and negatively correlated with greater internalized stigma and perceptions of others devaluing families of individuals with AN. Together, these factors accounted for 63% of the variance in recovery attitudes. Findings demonstrate the adverse effects perceived stigma towards families, self-stigma, and self-esteem have on recovery attitudes in individuals with AN. Clinical interventions are needed to challenge internalized stigma and bolster self-esteem to enhance individuals' recovery efforts. PMID:26894311

  20. Young adult Ecstasy users' enhancement of the effects of their Ecstasy use.

    Science.gov (United States)

    Klein, Hugh; Elifson, Kirk W; Sterk, Claire E

    2009-06-01

    This study examines drug effect-enhancing behaviors practiced by young adult users of the drug, Ecstasy. Between August 2002 and August 2004, 283 face-to-face interviews were conducted with active Ecstasy users. Study participants were recruited in the Atlanta, Georgia metropolitan area using a targeted sampling approach. The large majority of study participants (87%) engaged in at least one behavior specifically designed to bolster the effects of their Ecstasy use, with 61% of the study participants reporting having engaged in at least three such behaviors during the past 30 days. Taking steps to boost one's Ecstasy-related high was associated with binging on Ecstasy and a variety of adverse outcomes, such as experiencing a greater number of negative consequences resulting from Ecstasy use and experiencing more Ecstasy-related drug dependency symptoms. Multivariate analysis revealed several factors associated with greater involvement in effects-boosting behaviors, including race (not being African American), spending time with other drug users, using Ecstasy for its touch-enhancing qualities, enjoyment of the music-and-Ecstasy-use experience, and childhood maltreatment experiences. The implications of these findings for treatment, prevention, and intervention for drug problems among Ecstasy users are discussed. PMID:19705673

  1. Mandating supplemental intervention services: Is New York state doing enough to help all students succeed?

    Directory of Open Access Journals (Sweden)

    Kieran M. Killeen

    2005-03-01

    Full Text Available As states have become more active in establishing curriculum content standards and related assessments disappointingly little attention has been paid to policy efforts that create learning opportunities for students to meet the new standards. This study examines one state policy designed to bolster the opportunity to learn by mandating additional instruction for students not currently achieving proficiency in the state standards. The results focus on a detailed description of New York State's Academic Intervention Services, including its organizational and instructional elements (e.g., staffing, scheduling, student grouping, instructional strategies across NYS schools. While the majority of states have established curriculum frameworks and linked them to assessment instruments, this experience in NY may be unique for its coordinated emphasis on intervention services (academic and non-academic linked to rigorous learning and accountability standards. However, the caveats identified in this study promote a familiar sense of local discretion in the interpretation and implementation of state policy mandates. The analyses describe how such practices vary by local district context, such as community wealth and geography, and if those practices have equity implications. The primary analyses draw on survey data from a stratified random sample of 764 teachers and principals from 125 school districts, and feature multi-variate methods with proper adjustment for the clustering of responses within districts (i.e., multiple teachers and administrators within each district.

  2. Gravitational anomalies and one-dimensional behavior of black holes

    Energy Technology Data Exchange (ETDEWEB)

    Majhi, Bibhas Ranjan, E-mail: bibhas.majhi@iitg.ernet.in [Department of Physics, Indian Institute of Technology Guwahati, 781039, Guwahati, Assam (India)

    2015-12-08

    It has been pointed out by Bekenstein and Mayo that the behavior of the black hole’s entropy or information flow is similar to information flow through one-dimensional channel. Here I analyze the same issue with the use of gravitational anomalies. The rate of the entropy change (S{sup .}) and the power (P) of the Hawking emission are calculated from the relevant components of the anomalous stress tensor under the Unruh vacuum condition. I show that the dependence of S{sup .} on the power is S{sup .} ∝P{sup 1/2}, which is identical to that for the information flow in a one-dimensional system. This is established by using the (1+1)-dimensional gravitational anomalies first. Then the fact is further bolstered by considering the (1+3)-dimensional gravitational anomalies. It is found that, in the former case, the proportionality constant is exactly identical to the one-dimensional situation, known as Pendry’s formula, while in the latter situation its value decreases.

  3. Transforming followers' value internalization and role self-efficacy: Dual processes promoting performance and peer norm-enforcement.

    Science.gov (United States)

    Hannah, Sean T; Schaubroeck, John M; Peng, Ann C

    2016-02-01

    We develop a model in which transformational leadership bolsters followers' internalization of core organizational values, which in turn influences their performance and willingness to report peers' transgressions. The model also specifies a distinct process wherein transformational leadership enhances follower performance by promoting followers' role self-efficacy. We tested the model on 2 large units (i.e., companies) of soldiers undergoing training and socialization. The study bracketed changes in soldiers' internalization of the organizational values and role self-efficacy over a 14-week period. The results support the widely held but empirically unestablished views that transformational leadership promotes change in value internalization and that this partially explains its influence on follower performance. Findings also indicate a distinct intervening process through which transformational leadership promotes performance by enhancing followers' beliefs in their own capabilities (i.e., self-efficacy). This research thus shows that 2 key processes both contribute to the understanding of how transformational leadership transforms followers and influences their behavior. PMID:26167644

  4. Learning from dying patients during their final days: life reflections gleaned from dignity therapy.

    Science.gov (United States)

    Hack, Thomas F; McClement, Susan E; Chochinov, Harvey M; Cann, Beverley J; Hassard, Thomas H; Kristjanson, Linda J; Harlos, Mike

    2010-10-01

    Dignity therapy is a novel therapeutic approach designed to decrease suffering, enhance quality of life and bolster a sense of dignity for patients approaching death. The benefits of dignity therapy were previously documented in a sample of 100 terminally ill patients. One of the products of dignity therapy is a transcript of the edited therapy session(s). In this qualitative study, 50 of the 100 (17 from Winnipeg, Manitoba, Canada, and 33 from Perth, Australia) dignity therapy transcripts were randomly drawn, and independently coded and analysed by three investigators using a grounded theory approach. The transcripts revealed that dignity therapy serves to provide a safe, therapeutic environment for patients to review the most meaningful aspects of their lives in such a manner that their core values become apparent. The most common values expressed by the patients included 'Family', 'Pleasure', 'Caring', 'A Sense of Accomplishment', 'True Friendship', and 'Rich Experience'. Exemplars of each of these values illustrate the pervasive, defining role of values in our lives. The findings are discussed in terms of values theory, the role of dignity therapy, and consideration of values clarification in clinicians' efforts to enhance the dignity of terminally ill patients. PMID:20605851

  5. Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence.

    Science.gov (United States)

    Mattson, Mark P

    2015-03-01

    Although the human brain is exceptional in size and information processing capabilities, it is similar to other mammals with regard to the factors that promote its optimal performance. Three such factors are the challenges of physical exercise, food deprivation/fasting, and social/intellectual engagement. Because it evolved, in part, for success in seeking and acquiring food, the brain functions best when the individual is hungry and physically active, as typified by the hungry lion stalking and chasing its prey. Indeed, studies of animal models and human subjects demonstrate robust beneficial effects of regular exercise and intermittent energy restriction/fasting on cognitive function and mood, particularly in the contexts of aging and associated neurodegenerative disorders. Unfortunately, the agricultural revolution and the invention of effort-sparing technologies have resulted in a dramatic reduction or elimination of vigorous exercise and fasting, leaving only intellectual challenges to bolster brain function. In addition to disengaging beneficial adaptive responses in the brain, sedentary overindulgent lifestyles promote obesity, diabetes and cardiovascular disease, all of which may increase the risk of cognitive impairment and Alzheimer's disease. It is therefore important to embrace the reality of the requirements for exercise, intermittent fasting and critical thinking for optimal brain health throughout life, and to recognize the dire consequences for our aging population of failing to implement such brain-healthy lifestyles. PMID:25576651

  6. Determining the Appropriate Package and Transportation Methodology for the Detroit Edison, Fermi II Msrs and Associated Components

    International Nuclear Information System (INIS)

    During the spring of 2005, Detroit Edison, Enrico Fermi II Nuclear Power Station (Fermi) decided to disposition two MSRs and associated components scheduled for replacement in the spring of 2006 during the MSR Replacement Outage. Of concern to Fermi was the proper packaging and transportation methodology when dis-positioning a component measuring approximately 110' in length and 13' in diameter and weighing over 300 tons. Upon removal from the Turbine Deck the retired MSRs and associated components were turned over to the Rad Waste Group for packaging and final disposition. Fermi requested quotations from vendors to package, transport, and disposition the MSRs and associated components. However, multiple Vendors informed Fermi that the size and weight of the MSRs were questionable in passing permitting requirements and would require segmentation and volume reduction on site or at a waste processor. Fermi contracted with MHF Logistical Solutions (MHF-LS) based on their ability to receive clearances for shipping the MSRs in one piece via two heavy haul rail conveyances acting as a bolstered load with professionally engineered blocking and bracing configured to support the retired MSRs. (authors)

  7. Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress.

    Science.gov (United States)

    Jaiswal, Manish; Haelterman, Nele A; Sandoval, Hector; Xiong, Bo; Donti, Taraka; Kalsotra, Auinash; Yamamoto, Shinya; Cooper, Thomas A; Graham, Brett H; Bellen, Hugo J

    2015-07-01

    Two insults often underlie a variety of eye diseases including glaucoma, optic atrophy, and retinal degeneration--defects in mitochondrial function and aberrant Rhodopsin trafficking. Although mitochondrial defects are often associated with oxidative stress, they have not been linked to Rhodopsin trafficking. In an unbiased forward genetic screen designed to isolate mutations that cause photoreceptor degeneration, we identified mutations in a nuclear-encoded mitochondrial gene, ppr, a homolog of human LRPPRC. We found that ppr is required for protection against light-induced degeneration. Its function is essential to maintain membrane depolarization of the photoreceptors upon repetitive light exposure, and an impaired phototransduction cascade in ppr mutants results in excessive Rhodopsin1 endocytosis. Moreover, loss of ppr results in a reduction in mitochondrial RNAs, reduced electron transport chain activity, and reduced ATP levels. Oxidative stress, however, is not induced. We propose that the reduced ATP level in ppr mutants underlies the phototransduction defect, leading to increased Rhodopsin1 endocytosis during light exposure, causing photoreceptor degeneration independent of oxidative stress. This hypothesis is bolstered by characterization of two other genes isolated in the screen, pyruvate dehydrogenase and citrate synthase. Their loss also causes a light-induced degeneration, excessive Rhodopsin1 endocytosis and reduced ATP without concurrent oxidative stress, unlike many other mutations in mitochondrial genes that are associated with elevated oxidative stress and light-independent photoreceptor demise. PMID:26176594

  8. Russian view of ventures brightens

    International Nuclear Information System (INIS)

    Russia's attitude toward prospects for massive foreign investment in its ailing petroleum industry has shifted from ill-concealed disappointment to widely expressed optimism. Major exploration and development deals that have been long delayed and often verged on collapse are now being implemented at an accelerating pace. Moscow media reports, which as recently as last winter emphasized the meager number and relatively small size of active foreign joint ventures designed to bolster sagging oil output, have turned distinctly upbeat. That also contrasts with attacks in recent months by Russian media against high profile ventures such as Chevron Corp.'s Tengiz project and the Sakhalin Island tender process. Problems remain involving taxes, bureaucratic foot-dragging, and fears of capitalist exploitation of Russian natural resources. Add to that the Yeltsin administration's slowdown in its drive toward a market economy, Russia's desperate financial plight, and rumors of another coup attempt by hardline Communists. This paper reports that all these factors, however, haven't dampened growing belief that the outlook for agreements on mutually profitable, long term petroleum deals involving billions of dollars has become more favorable

  9. Making the innovation case in Open Access scholary communication

    CERN Document Server

    CERN. Geneva

    2005-01-01

    It seems almost unnecessary to have to elaborate additional reasons for the adoption of Open Access scholarly communication (OA sc) as manifested through Open Access journals and self-archiving practices. To those active within the OA arena, the case has been convincingly made, and current arguments merely need to be disseminated beyond the Library and Information Science (LIS) sphere. However, it is my contention that a convincing argument for OA sc needs to be launched from the Science Policy perspective if any government mandated pro-OA policy changes are to be effected. This paper, then, is an attempt at taking the OA discussion beyond the LIS arena and into the realm of Science and Innovation Policy. Using Innovation Theory as its theoretical framework, it is argued that Open Access scholarly communication can only serve to bolster Innovation Systems, be they national, regional, or sectoral. The case of South Africa is taken as an illustrative example, though the case can and will be generalised to beyon...

  10. Optimizing Health Care Coalitions: Conceptual Frameworks and a Research Agenda.

    Science.gov (United States)

    Hupert, Nathaniel; Biala, Karen; Holland, Tara; Baehr, Avi; Hasan, Aisha; Harvey, Melissa

    2015-12-01

    The US health care system has maintained an objective of preparedness for natural or manmade catastrophic events as part of its larger charge to deliver health services for the American population. In 2002, support for hospital-based preparedness activities was bolstered by the creation of the National Bioterrorism Hospital Preparedness Program, now called the Hospital Preparedness Program, in the US Department of Health and Human Services. Since 2012, this program has promoted linking health care facilities into health care coalitions that build key preparedness and emergency response capabilities. Recognizing that well-functioning health care coalitions can have a positive impact on the health outcomes of the populations they serve, this article informs efforts to optimize health care coalition activity. We first review the landscape of health care coalitions in the United States. Then, using principles from supply chain management and high-reliability organization theory, we present 2 frameworks extending beyond the Office of the Assistant Secretary for Preparedness and Response's current guidance in a way that may help health care coalition leaders gain conceptual insight into how different enterprises achieve similar ends relevant to emergency response. We conclude with a proposed research agenda to advance understanding of how coalitions can contribute to the day-to-day functioning of health care systems and disaster preparedness. PMID:26545194

  11. Brief intervention to encourage empathic discipline cuts suspension rates in half among adolescents.

    Science.gov (United States)

    Okonofua, Jason A; Paunesku, David; Walton, Gregory M

    2016-05-10

    Growing suspension rates predict major negative life outcomes, including adult incarceration and unemployment. Experiment 1 tested whether teachers (n = 39) could be encouraged to adopt an empathic rather than punitive mindset about discipline-to value students' perspectives and sustain positive relationships while encouraging better behavior. Experiment 2 tested whether an empathic response to misbehavior would sustain students' (n = 302) respect for teachers and motivation to behave well in class. These hypotheses were confirmed. Finally, a randomized field experiment tested a brief, online intervention to encourage teachers to adopt an empathic mindset about discipline. Evaluated at five middle schools in three districts (Nteachers = 31; Nstudents = 1,682), this intervention halved year-long student suspension rates from 9.6% to 4.8%. It also bolstered respect the most at-risk students, previously suspended students, perceived from teachers. Teachers' mindsets about discipline directly affect the quality of teacher-student relationships and student suspensions and, moreover, can be changed through scalable intervention. PMID:27114516

  12. Potential factors that may promote successful cognitive aging

    Directory of Open Access Journals (Sweden)

    Vance DE

    2012-06-01

    Full Text Available David E VanceCenter for Nursing Research, School of Nursing, Edward R Roybal Center for Translational Research in Aging and Mobility, University of Alabama at Birmingham (UAB, Birmingham, AL, USAAbstract: With the unprecedented number of older adults worldwide, it is important to consider ways of facilitating successful cognitive aging. One way to think of this is by augmenting or bolstering cognitive reserve. Loosely defined, cognitive reserve is considered a neurological reservoir that can be depleted by physiological insults (eg, white matter hyperintensities, oxidative stress to the brain but yet maintain optimal cognitive functioning. Cognitive reserve is built up or depleted by processes of positive and negative neuroplasticity, respectively. Lifestyle factors such as physical exercise (+, mental stimulation (+, good sleep hygiene (+, substance abuse (-, sedentary lifestyle (-, chronic stress and depression (-, social isolation (-, and poor health (- can either promote or discourage positive and negative neuroplasticity, which in turn impacts cognitive reserve. Nurses are encouraged to understand these processes so they can help facilitate successful cognitive aging in their patients.Keywords: cognitive reserve, Alzheimer's disease, neuroplasticity

  13. Integrating Diverse Types of Genomic Data to Identify Genes that Underlie Adverse Pregnancy Phenotypes.

    Directory of Open Access Journals (Sweden)

    Jibril Hirbo

    Full Text Available Progress in understanding complex genetic diseases has been bolstered by synthetic approaches that overlay diverse data types and analyses to identify functionally important genes. Pre-term birth (PTB, a major complication of pregnancy, is a leading cause of infant mortality worldwide. A major obstacle in addressing PTB is that the mechanisms controlling parturition and birth timing remain poorly understood. Integrative approaches that overlay datasets derived from comparative genomics with function-derived ones have potential to advance our understanding of the genetics of birth timing, and thus provide insights into the genes that may contribute to PTB. We intersected data from fast evolving coding and non-coding gene regions in the human and primate lineage with data from genes expressed in the placenta, from genes that show enriched expression only in the placenta, as well as from genes that are differentially expressed in four distinct PTB clinical subtypes. A large fraction of genes that are expressed in placenta, and differentially expressed in PTB clinical subtypes (23-34% are fast evolving, and are associated with functions that include adhesion neurodevelopmental and immune processes. Functional categories of genes that express fast evolution in coding regions differ from those linked to fast evolution in non-coding regions. Finally, there is a surprising lack of overlap between fast evolving genes that are differentially expressed in four PTB clinical subtypes. Integrative approaches, especially those that incorporate evolutionary perspectives, can be successful in identifying potential genetic contributions to complex genetic diseases, such as PTB.

  14. [Cognitive Function and Calcium. Ca2+-dependent regulatory mechanism of circadian clock oscillation and its relevance to neuronal function].

    Science.gov (United States)

    Kon, Naohiro; Fukada, Yoshitaka

    2015-02-01

    Circadian clock generates a variety of biological rhythms such as sleep/wake cycles and blood hormone rhythms. The circadian clock also bolsters daily mental activities. In fact, abnormalities of the circadian rhythms are found in several neurological disorders. The circadian clock has two important functions: (i) a cell-autonomous oscillatory function and (ii) a phase-adjusting function that synchronizes the clock oscillation with environmental cycling conditions such as light/dark cycle. Behavioral rhythms are controlled by the central clock in hypothalamic suprachiasmatic nucleus (SCN). The central clock orchestrates peripheral clocks in the other tissues via neuronal connection and/or actions of humoral factors. The molecular mechanism of the cell-autonomous clock is based on transcriptional feedback regulation of clock genes by their encoded products. Ca2+ is essential for not only the light response of the clock but also the cell autonomous oscillation mechanism. This article provides an overview of recent progress in studies of Ca2+-dependent regulatory mechanism of the molecular clockwork. PMID:25634045

  15. Genetic Variability and Phylogenetic Relationships within Trypanosoma cruzi I Isolated in Colombia Based on Miniexon Gene Sequences

    Directory of Open Access Journals (Sweden)

    Claudia Herrera

    2009-01-01

    Full Text Available Phylogenetic studies of Trypanosoma cruzi have identified the existence of two groups: T. cruzi I and T. cruzi II. There are aspects that still remain unknown about the genetic variability within the T. cruzi I group. Given its epidemiological importance, it is necessary to have a better understanding of T. cruzi transmission cycles. Our purpose was to corroborate the existence of haplotypes within the T. cruzi I group and to describe the genetic variability and phylogenetic relationships, based on single nucleotide polymorphisms (SNPs found in the miniexon gene intergenic region, for the isolates from different hosts and epidemiological transmission cycles in Colombian regions. 31 T. cruzi isolates were molecularly characterized. Phylogenetic relationships within T. cruzi I isolates showed four haplotype groups (Ia–Id, associated with their transmission cycle. In previous studies, we reported that haplotype Ia is mainly associated with the domestic cycle and domiciliated Rhodnius prolixus. Haplotype Ib is associated with the domestic cycle and peridomestic cycle, haplotype Ic is closely related with the peridomestic cycle, and haplotype Id is strongly associated with the sylvatic cycle. The phylogenetic methodologies applied in this study are tools that bolster the associations among isolates and thus shed light on Chagas disease epidemiology.

  16. "I used to be an ordinary mom": The maternal identity of mothers of women abused by an intimate partner.

    Science.gov (United States)

    Gueta, Keren; Peled, Einat; Sander-Almoznino, Nili

    2016-01-01

    Mothers of children who suffer various problems tend to discuss their experience as a crisis in their maternal identity, regardless of whether the children are young or adults. However, the maternal identity of mothers who are aware that their adult daughters are being abused has not yet been explored. This study aims to examine the construction of the maternal identity by Israeli women whose grown daughters have been subjected to intimate partner violence (IPV), in the light of cultural representations of motherhood and domestic violence (DV). Thematic discourse analysis of in-depth interviews with 11 mothers identified discursive strategies that they used to negotiate a troubled maternal identity following their daughters' IPV experience. The mothers asserted a positive maternal identity by referring to common discourses about DV and motherhood, in a bid to bolster their "good mother" identity, to reframe motherhood, and to assign responsibility for the abuse to the abuser, to their daughters, or to the patriarchal social structure. The implications of these findings for motherhood and maternal identity theories and for professionals working in the field of DV are discussed. (PsycINFO Database Record PMID:26752440

  17. The next frontier in composite tissue allotransplantation.

    Science.gov (United States)

    Ren, Xiaoping; Laugel, Michael C

    2013-01-01

    Solid organ transplantations became a clinical option in the 1950s. The hand allograft was the pioneer of composite tissue allotransplantation (CTA), successfully started near the end of the last century despite arguments over the practicality and methods. Since then, CTA such as hand and face has continued to progress from the theoretical to clinical reality. The treatment principles, drug combinations, and mechanisms of the immunosuppression medications on which contemporary transplant surgeries have been based continue to develop as researchers and physicians gain more experience in the CTA field. It could be argued that the ethical issues associated with CTA have prevented evolution of the field rather than surgical or technical skill. This is particularly true for allo-head and body reconstruction (AHBR). How can leaders in the field of CTA develop a model that would satisfy ethical concerns? Bolstered by recent successes in the field, is it time to traverse the next frontier? Can AHBR ever be a feasible option in the clinical setting? The reader will be provided with a brief history of CTA from theory to research to clinical practice. A concise description of AHBR as it pertains to the critical procedure (i.e., surgery design) will also be discussed. PMID:23157698

  18. Portugal: participation in peace missions as a factor of external credibility

    Directory of Open Access Journals (Sweden)

    Maria do Céu Pinto

    2012-01-01

    Full Text Available In per capita terms, Portugal is one of the most significant European contributors to international peacekeeping operations around the world. It presently ranks 45th in a list of 115 countries contributing to the United Nations (UN peace operations and 7th in the European Union (EU. The multiplicity of forces used, as well as the diversity of the locations of deployment, reflect the ambition and effort made by the Portuguese governments in the last 20 years. Portuguese participation in peacekeeping missions has been seen as a vehicle for strengthening Portugal’s position in the world: the involvement under the flag of international organisations raises the profile of Portuguese foreign policy and diplomacy. In this paper, we argue that Portuguese involvement in peace missions reflects Portugal’s pursuit of its national interest and foreign policy. The aim is to bolster Portugal’s capacity to influence the decision-making process in major international fora, such as the UN, NATO and the EU. The goal established since the late 1980s aims to strengthen the visibility and specific weight of Portugal in the multilateral framework. The country´s contribution to peacekeeping operations has increased the bargaining power of Portugal, which has become an active partner with a more audible voice within those organisations. That voice led to gaining a better position when it came to negotiating major international posts and policies.

  19. The potential of crowdsourcing and mobile technology to support flood disaster risk reduction

    Science.gov (United States)

    See, Linda; McCallum, Ian; Liu, Wei; Mechler, Reinhard; Keating, Adriana; Hochrainer-Stigler, Stefan; Mochizuki, Junko; Fritz, Steffen; Dugar, Sumit; Arestegui, Michael; Szoenyi, Michael; Laso-Bayas, Juan-Carlos; Burek, Peter; French, Adam; Moorthy, Inian

    2016-04-01

    The last decade has seen a rise in citizen science and crowdsourcing for carrying out a variety of tasks across a number of different fields, most notably the collection of data such as the identification of species (e.g. eBird and iNaturalist) and the classification of images (e.g. Galaxy Zoo and Geo-Wiki). Combining human computing with the proliferation of mobile technology has resulted in vast amounts of geo-located data that have considerable value across multiple domains including flood disaster risk reduction. Crowdsourcing technologies, in the form of online mapping, are now being utilized to great effect in post-disaster mapping and relief efforts, e.g. the activities of Humanitarian OpenStreetMap, complementing official channels of relief (e.g. Haiti, Nepal and New York). Disaster event monitoring efforts have been further complemented with the use of social media (e.g. twitter for earthquakes, flood monitoring, and fire detection). Much of the activity in this area has focused on ex-post emergency management while there is considerable potential for utilizing crowdsourcing and mobile technology for vulnerability assessment, early warning and to bolster resilience to flood events. This paper examines the use of crowdsourcing and mobile technology for measuring and monitoring flood hazards, exposure to floods, and vulnerability, drawing upon examples from the literature and ongoing projects on flooding and food security at IIASA.

  20. A Review of the Water and Energy Sectors and the Use of a Nexus Approach in Abu Dhabi

    Science.gov (United States)

    Paul, Parneet; Al Tenaiji, Ameena Kulaib; Braimah, Nuhu

    2016-01-01

    Rapid population increase coupled with urbanization and industrialization has resulted in shortages of water in the Middle East. This situation is further exacerbated by global climate change due to greenhouse gas emissions. Recent research advocates that solutions to the global water security and scarcity crisis must involve water–energy nexus approaches. This means adopting policies and strategies that harmonize these inter-related sectors to minimize environmental impact while maximizing human benefit. In the case of Abu Dhabi, when designing and locating oil/gas refineries and associated power generation facilities, previous relevant decisions were based on simple economic and geographical grounds, such as nearness to oil rigs, pipelines, existing industries and port facilities, etc. The subsequent design and location of water abstraction and treatment works operated by the waste heat from these refining and/or power generation processes was catered for as an afterthought, meaning that there is now a mismatch between the water and energy supplies and demands. This review study was carried out to show how Abu Dhabi is trying now to integrate its water–energy sectors using a nexus approach so that future water/power infrastructure is designed optimally and operated in harmony, especially in regard to future demand. Based upon this review work, some recommendations are made for designers and policy makers alike to bolster the nexus approach that Abu Dhabi is pursuing. PMID:27023583

  1. Detection of Abiotic Methane in Terrestrial Continental Hydrothermal Systems: Implications for Methane on Mars

    Science.gov (United States)

    Socki, Richard A.; Niles, Paul B.; Gibson, Everett K., Jr.; Romanek, Christopher S.; Zhang, Chuanlun L.; Bissada, Kadry K.

    2008-01-01

    The recent detection of methane in the Martian atmosphere and the possibility that its origin could be attributed to biological activity, have highlighted the importance of understanding the mechanisms of methane formation and its usefulness as a biomarker. Much debate has centered on the source of the methane in hydrothermal fluids, whether it is formed biologically by microorganisms, diagenetically through the decomposition of sedimentary organic matter, or inorganically via reduction of CO2 at high temperatures. Ongoing research has now shown that much of the methane present in sea-floor hydrothermal systems is probably formed through inorganic CO2 reduction processes at very high temperatures (greater than 400 C). Experimental results have indicated that methane might form inorganically at temperatures lower still, however these results remain controversial. Currently, methane in continental hydrothermal systems is thought to be formed mainly through the breakdown of sedimentary organic matter and carbon isotope equilibrium between CO2 and CH4 is thought to be rarely present if at all. Based on isotopic measurements of CO2 and CH4 in two continental hydrothermal systems, we suggest that carbon isotope equilibration exists at temperatures as low as 155 C. This would indicate that methane is forming through abiotic CO2 reduction at lower temperatures than previously thought and could bolster arguments for an abiotic origin of the methane detected in the martian atmosphere.

  2. Do Smallholder, Mixed Crop-Livestock Livelihoods Encourage Sustainable Agricultural Practices? A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Thomas K. Rudel

    2016-02-01

    Full Text Available As calls for bolstering ecosystem services from croplands have grown more insistent during the past two decades, the search for ways to foster these agriculture-sustaining services has become more urgent. In this context we examine by means of a meta-analysis the argument, proposed by Robert McC. Netting, that small-scale, mixed crop-livestock farming, a common livelihood among poor rural peoples, leads to environmentally sustainable agricultural practices. As predicted, mixed crop-livestock farms exhibit more sustainable practices, but, contrary to predictions, a small scale of operation does not predict sustainability. Many smallholders on mixed crop-livestock farms use sustainable practices, but other smallholders practice a degrading, input-scarce agriculture. Some large farm operators use soil-conserving, minimum-tillage techniques while other large operators ignore soil-conserving techniques and practice an industrialized, high chemical input agriculture. The strength and pervasiveness of the link in the data between mixed crop-livestock farming and sustainable agricultural practices argues for agricultural policies that promote mixed crop-livestock livelihoods.

  3. Code Forking, Governance, and Sustainability in Open Source Software

    Directory of Open Access Journals (Sweden)

    Juho Lindman

    2013-01-01

    Full Text Available The right to fork open source code is at the core of open source licensing. All open source licenses grant the right to fork their code, that is to start a new development effort using an existing code as its base. Thus, code forking represents the single greatest tool available for guaranteeing sustainability in open source software. In addition to bolstering program sustainability, code forking directly affects the governance of open source initiatives. Forking, and even the mere possibility of forking code, affects the governance and sustainability of open source initiatives on three distinct levels: software, community, and ecosystem. On the software level, the right to fork makes planned obsolescence, versioning, vendor lock-in, end-of-support issues, and similar initiatives all but impossible to implement. On the community level, forking impacts both sustainability and governance through the power it grants the community to safeguard against unfavourable actions by corporations or project leaders. On the business-ecosystem level forking can serve as a catalyst for innovation while simultaneously promoting better quality software through natural selection. Thus, forking helps keep open source initiatives relevant and presents opportunities for the development and commercialization of current and abandoned programs.

  4. Transmission and epidemiology of zoonotic protozoal diseases of companion animals.

    Science.gov (United States)

    Esch, Kevin J; Petersen, Christine A

    2013-01-01

    Over 77 million dogs and 93 million cats share our households in the United States. Multiple studies have demonstrated the importance of pets in their owners' physical and mental health. Given the large number of companion animals in the United States and the proximity and bond of these animals with their owners, understanding and preventing the diseases that these companions bring with them are of paramount importance. Zoonotic protozoal parasites, including toxoplasmosis, Chagas' disease, babesiosis, giardiasis, and leishmaniasis, can cause insidious infections, with asymptomatic animals being capable of transmitting disease. Giardia and Toxoplasma gondii, endemic to the United States, have high prevalences in companion animals. Leishmania and Trypanosoma cruzi are found regionally within the United States. These diseases have lower prevalences but are significant sources of human disease globally and are expanding their companion animal distribution. Thankfully, healthy individuals in the United States are protected by intact immune systems and bolstered by good nutrition, sanitation, and hygiene. Immunocompromised individuals, including the growing number of obese and/or diabetic people, are at a much higher risk of developing zoonoses. Awareness of these often neglected diseases in all health communities is important for protecting pets and owners. To provide this awareness, this review is focused on zoonotic protozoal mechanisms of virulence, epidemiology, and the transmission of pathogens of consequence to pet owners in the United States. PMID:23297259

  5. Improving the World’s Health through the Post-2015 Development Agenda: Perspectives from Rwanda

    Directory of Open Access Journals (Sweden)

    Agnes Binagwaho

    2015-04-01

    Full Text Available The world has made a great deal of progress through the Millennium Development Goals (MDGs to improve the health and well-being of people around the globe, but there remains a long way to go. Here we provide reflections on Rwanda’s experience in working to meet the health-related targets of the MDGs. This experience has informed our proposal of five guiding principles that may be useful for countries to consider as the world sets and moves forward with the post-2015 development agenda. These include: 1 advancing concrete and meaningful equity agendas that drive the post-2015 goals; 2 ensuring that goals to meet Universal Health Coverage (UHC incorporate real efforts to focus on improving quality and not only quantity of care; 3 bolstering education and the internal research capacity within countries so that they can improve local evidence-based policy-making; 4 promoting intersectoral collaboration to achieve goals, and 5 improving collaborations between multilateral agencies – that are helping to monitor and evaluate progress towards the goals that are set – and the countries that are working to achieve improvements in health within their nation and across the world

  6. The Navajo Learning Network and the NASA Life Sciences/AFOSR Infrastructure Development Project

    Science.gov (United States)

    1999-01-01

    The NSF-funded Navajo Learning Network project, with help from NASA Life Sciences and AFOSR, enabled Dine College to take a giant leap forward technologically - in a way that could never had been possible had these projects been managed separately. The combination of these and other efforts created a network of over 500 computers located at ten sites across the Navajo reservation. Additionally, the college was able to install a modern telephone system which shares network data, and purchase a new higher education management system. The NASA Life Sciences funds further allowed the college library system to go online and become available to the entire campus community. NSF, NASA and AFOSR are committed to improving minority access to higher education opportunities and promoting faculty development and undergraduate research through infrastructure support and development. This project has begun to address critical inequalities in access to science, mathematics, engineering and technology for Navajo students and educators. As a result, Navajo K-12 education has been bolstered and Dine College will therefore better prepare students to transfer successfully to four-year institutions. Due to the integration of the NSF and NASA/AFOSR components of the project, a unified project report is appropriate.

  7. CD40 signaling synergizes with TLR-2 in the BCR independent activation of resting B cells.

    Science.gov (United States)

    Jain, Shweta; Chodisetti, Sathi Babu; Agrewala, Javed N

    2011-01-01

    Conventionally, signaling through BCR initiates sequence of events necessary for activation and differentiation of B cells. We report an alternative approach, independent of BCR, for stimulating resting B (RB) cells, by involving TLR-2 and CD40--molecules crucial for innate and adaptive immunity. CD40 triggering of TLR-2 stimulated RB cells significantly augments their activation, proliferation and differentiation. It also substantially ameliorates the calcium flux, antigen uptake capacity and ability of B cells to activate T cells. The survival of RB cells was improved and it increases the number of cells expressing activation induced deaminase (AID), signifying class switch recombination (CSR). Further, we also observed increased activation rate and decreased threshold period required for optimum stimulation of RB cells. These results corroborate well with microarray gene expression data. This study provides novel insights into coordination between the molecules of innate and adaptive immunity in activating B cells, in a BCR independent manner. This strategy can be exploited to design vaccines to bolster B cell activation and antigen presenting efficiency, leading to faster and better immune response. PMID:21674065

  8. Inside the whale: the structure and dynamics of the isolated Cetus dwarf spheroidal

    CERN Document Server

    Lewis, G F; Chapman, S C; McConnachie, A; Irwin, M J; Tolstoy, E; Tanvir, N R

    2006-01-01

    This paper presents a study of the Cetus dwarf, an isolated dwarf galaxy within the Local Group. A matched-filter analysis of the INT/WFC imaging of this system reveals no evidence for significant tidal debris that could have been torn from the galaxy, bolstering the hypothesis that Cetus has never significantly interacted with either the Milky Way or M31. Additionally, Keck/Deimos spectroscopic observations identify this galaxy as a distinct kinematic population possessing a systematic velocity of $-87\\pm2{\\rm km\\ s^{-1}}$ and with a velocity dispersion of $17\\pm2{\\rm km s^{-1}}$; while tentative, these data also suggest that Cetus possesses a moderate rotational velocity of $\\sim8{\\rm km s^{-1}}$. The population is confirmed to be relatively metal-poor, consistent with ${\\rm [Fe/H]\\sim-1.9}$, and, assuming virial equilibrium, implies that the Cetus dwarf galaxy possesses a $M/L\\sim70$. It appears, therefore, that Cetus may represent a primordial dwarf galaxy, retaining the kinematic and structural propertie...

  9. Validation of potential reference genes for qPCR in maize across abiotic stresses, hormone treatments, and tissue types.

    Directory of Open Access Journals (Sweden)

    Yueai Lin

    Full Text Available The reverse transcription quantitative polymerase chain reaction (RT-qPCR is a powerful and widely used technique for the measurement of gene expression. Reference genes, which serve as endogenous controls ensure that the results are accurate and reproducible, are vital for data normalization. To bolster the literature on reference gene selection in maize, ten candidate reference genes, including eight traditionally used internal control genes and two potential candidate genes from our microarray datasets, were evaluated for expression level in maize across abiotic stresses (cold, heat, salinity, and PEG, phytohormone treatments (abscisic acid, salicylic acid, jasmonic acid, ethylene, and gibberellins, and different tissue types. Three analytical software packages, geNorm, NormFinder, and Bestkeeper, were used to assess the stability of reference gene expression. The results revealed that elongation factor 1 alpha (EF1α, tubulin beta (β-TUB, cyclophilin (CYP, and eukaryotic initiation factor 4A (EIF4A were the most reliable reference genes for overall gene expression normalization in maize, while GRP (Glycine-rich RNA-binding protein, GLU1(beta-glucosidase, and UBQ9 (ubiquitin 9 were the least stable and most unsuitable genes. In addition, the suitability of EF1α, β-TUB, and their combination as reference genes was confirmed by validating the expression of WRKY50 in various samples. The current study indicates the appropriate reference genes for the urgent requirement of gene expression normalization in maize across certain abiotic stresses, hormones, and tissue types.

  10. Placentation in mammals once grouped as insectivores.

    Science.gov (United States)

    Carter, Anthony M; Enders, Allen C

    2010-01-01

    Interest in insectivoran grade mammals has been reawakened by taxonomic changes that place tenrecs and golden moles in a new order and separate hedgehogs from moles, shrews and solenodons. This survey of their placentation shows there is great variation even within families. As an example three subfamilies of tenrec have been examined. The interhemal region is cellular hemomonochorial in Echinops and Microgale but endotheliochorial in Micropotamogale. Golden moles, which are placed in the same order, have hemodichorial placentation. Many insectivores have complex arrangements for histotrophic nutrition involving columnar trophoblast cells. These range from areolae in moles through complexly folded hemophagous regions in tenrecs to the trophoblastic annulus in shrews. Of these placental characters, few offer support to current phylogenies. However, the case for placing hedgehogs and gymnures in a separate order (Erinaceomorpha) is bolstered by the presence of interstitial implantation, amniogenesis by cavitation, a hemochorial barrier and a prominent spongy zone; these features do not occur in shrews, moles or solenodons (Soricomorpha). Three insectivoran grade mammals deserve close attention as they have been selected for genome sequencing. One of these, the European hedgehog (Erinaceus europaeus), has not been studied with current methodology and renewed investigation of this or the closely related genus Atelerix should be a priority. PMID:19876821

  11. Exploring the Role of Self-Esteem and Parenting Patterns on Alcohol Use and Abuse Among Adolescents

    Science.gov (United States)

    Glozah, Franklin N.

    2014-01-01

    The type of parental child-rearing practices used by parents and guardians substantially influence children’s self-esteem and consequently their decision to engage in alcohol use, its abuse. The aim of this study was to explore the role of self-esteem and parenting patterns on alcohol use and abuse among adolescents. Three hundred and sixteen boys and girls in Senior High Schools completed self-report questionnaires assessing self-esteem, parenting patterns and alcohol use and abuse. The results showed that while girls reported lesser self-esteem than boys, boys reported higher levels of alcohol use and abuse than girls. Also, authoritative parenting pattern had a positive effect on self-esteem and a negative effect on alcohol use. On the other hand, authoritarian and permissive parenting patterns had negative effects on self-esteem and positive effects on alcohol use, with slight variations. These results provide valuable information regarding strategies aimed at fostering parent-child relationship and rapport with the ultimate aim of bolstering the self-esteem of adolescents to subsequently eschew insalubrious behaviour, particularly alcohol use and abuse. PMID:26973951

  12. A Dynamic Community of Discovery: Planning, Learning, and Change

    Directory of Open Access Journals (Sweden)

    Michelle Gordon

    2011-01-01

    Full Text Available Ryerson University’s Prior Learning and Competency Evaluation and Documentation (PLACED program is funded by the Government of Ontario to engage internationally educated professionals (IEPs, employers, and regulatory/occupational bodies in the use of competency-based practices. In 2008, the authors created a self-assessment tool for IEPs that would build a portfolio reflecting an individual’s knowledge and skills while introducing him or her to aspects of the Canadian workplace and labour market. The authors felt that this tool would be useful to assist IEPs in considering their career options and wanted to create an online workshop that would provide flexibility to users whose priorities were most likely work and family obligations. This short project description will capture a why the self-assessment tool was developed; (b how we fostered participants’ self-efficacy; c how we used Blackboard; (d what the participants gained from the workshop; and (e how the workshop has evolved based on facilitators’ observations, participants’ feedback, and an external organization’s request for customizing the workshop. In working together to design the online workshop, IEPs’ Self-Assessment and Planning, we focused on two main concepts: self-assessment and career planning. With that in mind, we set out in the workshop to bolster self-discovery, self-efficacy, individualized research skills, action planning, and ongoing professional development. The learning platform was Blackboard, which is used across Ryerson University in both classroom and online learning.

  13. Scientific Legitimation of the European Union’s Competence Development Policy

    Directory of Open Access Journals (Sweden)

    Rosario Sergio Maniscalco

    2012-01-01

    Full Text Available This study provides an accessible account of the policy making process of the European Union in the arena of adult skills and competence development. In particular, the way skill standards for adult learners is designed in the EU official statements is investigated, analyzing the developments in the European Union’s adult education policies since the Lisbon process was launched in order to verify to what extent they are evidence-based and legitimated through scientific research and specific ex-ante studies. In fact, because of the ageing work force in Europe, but also in the light of the recent economic downturns and the increased labor market’s flexibility and dynamics, many governments have tried to foster the involvement and participation of adults in lifelong learning paths for them to suit the transformations of the knowledge-based societies and be active and competitive even in older ages. This empirical paper is based on literature review and content analysis of the relevant policy documents and official EU statements. The main findings show how, beyond declared purposes and political slogans, the way the EU is shaping the adult learners’ upskilling significantly appears to aim at the substantial bolstering of basic and digital skills in order to cope with the knowledge economy rather than giving emphasis to more comprehensive sets of competences for lifelong learning and active ageing, which are going to be needed more than ever in the years to come.

  14. THE APPLICATION OF RADAR IN THE UDF DURING WORLD WAR II

    Directory of Open Access Journals (Sweden)

    T.C.B. Vlok

    2012-02-01

    Full Text Available Throughout the history of large decisive campaigns and wars, and more so when opposing forces are clearly defined, appearing on a massive scale, conventional weapons and methods of warfare are produced in enormous quantities, to be used by every able-bodied person available; this because every war holds the threat that a state of attrition will be reached when superiority in numbers will tip the scales. To bolster morale, to minimise what is indeed a fateful attitude, a great deal of effort and energy is devoted to developing the secret weapon, the one that will more than restore the balance. Such were in their time: ballistae, the short sword, bows and arrows, gunpowder, breech loading rifles, machine guns, submarines, aerial bombs, tanks, and poison gas. The World War II crop was roughly: Blitzkrieg, radar, V.-type bombs and the atomic bomb. Great leaps ahead like these, in advance of current practice, were the fruits of labour by devoted and untrammelled "Backroom Boys". They produced the strategic ideas and material which were then handed over to the combat forces to exploit tactically. With a strong element of secrecy and national security ever-present, it was invariably necessary to create new units in the field for such exploitation, rather than to extend the functions of existing organisations. It is against this background that the development of radar in the South African Armed Forces must be seen.

  15. Structural community factors and sub-optimal engagement in HIV care among low-income women in the Deep South of the USA.

    Science.gov (United States)

    Walcott, Melonie; Kempf, Mirjam-Colette; Merlin, Jessica S; Turan, Janet M

    2016-06-01

    This study describes the ways in which poverty and other structural factors create a risk environment for sub-optimal engagement in HIV care among low-income women living with HIV in the Southern USA, contributing to existing health disparities. We conducted a qualitative study in 2012, involving in-depth interviews with 14 stakeholders (service providers and representatives of community-based organisations) and 7 focus-group discussions with 46 women living with HIV (89% African American). A thematic approach in the context of the social ecological model guided data analysis. Data were coded and analysed using NVivo qualitative software. The findings suggested that structural community factors, such as poverty, poor employment opportunities, limited access to healthcare resources, stigma, transportation challenges and access to illicit substances, may work independently and in synergy to impact women's health seeking behaviour and decision-making, thereby influencing their ability to engage in HIV care. Interventions designed to improve engagement in HIV care should address structural factors to bolster low-income women's ability to engage in care. PMID:26670722

  16. Reconstructing the history of residence strategies in Indo-European-speaking societies: neo-, uxori-, and virilocality.

    Science.gov (United States)

    Fortunato, Laura

    2011-02-01

    Linguists and archaeologists have used reconstructions of early Indo-European residence strategies to constrain hypotheses about the homeland and trajectory of dispersal of Indo-European languages; however, these reconstructions are largely based on unsystematic and a historical use of the linguistic and ethnographic evidence, coupled with substantial bias in interpretation. Here I use cross-cultural data in a phylogenetic comparative framework to reconstruct the pattern of change in residence strategies in the history of societies speaking Indo-European languages. The analysis provides evidence in support of prevailing virilocality with alternative neolocality for Proto-Indo-European, and that this pattern may have extended back to Proto-Indo-Hittite. These findings bolster interpretations of the archaeological evidence that emphasize the "non-matricentric" structure of early Indo-European society; however, they also counter the notion that early Indo-European society was strongly "patricentric." I discuss implications of these findings in the context of the archaeological and genetic evidence on prehistoric social organization. PMID:21453007

  17. Eleven Tribes Jump START Clean Energy Projects, Summer 2012 (Newsletter)

    Energy Technology Data Exchange (ETDEWEB)

    2012-06-01

    This newsletter describes key activities of the DOE Office of Indian Energy Policy and Programs for Summer 2012. The U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) has selected 11 Tribes - five in Alaska and six in the contiguous United States - to receive on-the-ground technical support for community-based energy efficiency and renewable energy projects as part of DOE-IE's Strategic Technical Assistance Response Team (START) Program. START finalists were selected based on the clarity of their requests for technical assistance and the ability of START to successfully work with their projects or community. Technical experts from DOE and its National Renewable Energy Laboratory (NREL) will work directly with community-based project teams to analyze local energy issues and assist the Tribes in moving their projects forward. In Alaska, the effort will be bolstered by DOE-IE's partnership with the Denali Commission, which will provide additional assistance and expertise, as well as funding to fuel the Alaska START initiative.

  18. Canadian oilsands, heavy oil poised for surge in development

    International Nuclear Information System (INIS)

    Operators in Canada's oilsands and heavy oil regions are on the brink of a period of growth that could last well into the next century. Several factors are combining in a scenario a National Task Force report on oilsands says could dramatically increase investment and production in the next 25 years. By then, massive oilsands and heavy oil reserves in northern Alberta could account for as much as 50%--perhaps more--of Canada's oil production. Technological improvements in recovery and processing have slashed production costs and put nonconventional oil on a more competitive footing with declining reserves of conventional crude in western Canada. At the same time, persistent lobbying by industry and a well researched national study have persuaded federal and provincial governments to introduce a new royalty and fiscal regime designed to bolster oilsands investment. New policies give clear incentives to investors to put money into oilsands and heavy oil projects. Policies also will provide a generic tax treatment for all new projects, long a major objective of oilsands promoters. Previously, royalty and tax agreements were negotiated for project case by case. This paper reviews the resource base and the new operational developments resulting from these policies

  19. Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

    Directory of Open Access Journals (Sweden)

    Marc Mansour

    2011-08-01

    Full Text Available Chemotherapy has been a mainstay in cancer treatment for many years. Despite some success, the cure rate with chemotherapy remains unsatisfactory in some types of cancers, and severe side effects from these treatments are a concern. Recently, understanding of the dynamic interplay between the tumor and immune system has led to the development of novel immunotherapies, including cancer vaccines. Cancer vaccines have many advantageous features, but their use has been hampered by poor immunogenicity. Many developments have increased their potency in pre-clinical models, but cancer vaccines continue to have a poor clinical track record. In part, this could be due to an inability to effectively overcome tumor-induced immune suppression. It had been generally assumed that immune-stimulatory cancer vaccines could not be used in combination with immunosuppressive chemotherapies, but recent evidence has challenged this dogma. Chemotherapies could be used to condition the immune system and tumor to create an environment where cancer vaccines have a better chance of success. Other types of immunotherapies could also be used to modulate the immune system. This review will discuss how immune modulation by chemotherapy or immunotherapy could be used to bolster the effects of cancer vaccines and discuss the advantages and disadvantages of these treatments.

  20. How interdisciplinary is nanotechnology?

    International Nuclear Information System (INIS)

    Facilitating cross-disciplinary research has attracted much attention in recent years, with special concerns in nanoscience and nanotechnology. Although policy discourse has emphasized that nanotechnology is substantively integrative, some analysts have countered that it is really a loose amalgam of relatively traditional pockets of physics, chemistry, and other disciplines that interrelate only weakly. We are developing empirical measures to gauge and visualize the extent and nature of interdisciplinary interchange. Such results speak to research organization, funding, and mechanisms to bolster knowledge transfer. In this study, we address the nature of cross-disciplinary linkages using 'science overlay maps' of articles, and their references, that have been categorized into subject categories. We find signs that the rate of increase in nano research is slowing, and that its composition is changing (for one, increasing chemistry-related activity). Our results suggest that nanotechnology research encompasses multiple disciplines that draw knowledge from disciplinarily diverse knowledge sources. Nano research is highly, and increasingly, integrative-but so is much of science these days. Tabulating and mapping nano research activity show a dominant core in materials sciences, broadly defined. Additional analyses and maps show that nano research draws extensively upon knowledge presented in other areas; it is not constricted within narrow silos.

  1. Consanguinity Associated With Increased Risk for Bipolar I Disorder in Egypt

    Science.gov (United States)

    Mansour, Hader; Klei, Lambertus; Wood, Joel; Talkowski, Michael; Chowdari, Kodavali; Fathi, Warda; Eissa, Ahmed; Yassin, Amal; Salah, Hala; Tobar, Salwa; El-Boraie, Hala; Gaafar, Hanan; Elassy, Mai; Ibrahim, Nahed E.; El-Bahaei, Wafaa; Elsayed, Mohamed; Shahda, Mohamed; Sheshtawy, Eman El; El-Boraie, Osama; El-Chennawi, Farha; Devlin, Bernie; Nimgaonkar, Vishwajit L.

    2016-01-01

    We aimed to contrast rates of consanguinity among patients with bipolar I disorder (BP1) and controls in a population with customary consanguineous marriages (i.e., marriage between related individuals). Consanguinity increases risk for numerous monogenic and polygenic diseases. Whether the risk for BP1 increases with consanguinity has not been investigated systematically. Two independent studies were conducted in Egypt: (1) Case–control study 93 patients with BP1, 90 screened adult control individuals, and available parents. The inbreeding coefficient/consanguinity rate was estimated in two ways: using 64 DNA polymorphisms (“DNA-based” rate); and from family history data (“self report”); (2) Epidemiological survey: total of 1,584 individuals were screened, from whom self-reported consanguinity data were obtained for identified BP1 cases (n=35) and 150 randomly selected, unaffected control individuals. DNA-based consanguinity rates showed significant case–control control differences (P=0.0039). Self-reported consanguinity rates were also elevated among BP1 patients in both samples (Study #1 OR=2.66, 95% confidence intervals, CI: 1.34, 5.29; Study #2: OR=4.64, 95% CI: 2.01, 10.34). In conclusion, two independent, systematic studies indicate increased consanguinity among Egyptian BP1 patients in the Nile delta region. Self-reported estimates of consanguinity are bolstered by DNA-based estimates, and both show significant case–control differences for BP1. PMID:19152378

  2. Cats on the Couch: The Experimental Production of Animal Neurosis.

    Science.gov (United States)

    Winter, Alison

    2016-03-01

    Argument In the 1940s-50s, one of the most central questions in psychological research related to the nature of neurosis. In the final years of the Second World War and the following decade, neurosis became one of the most prominent psychiatric disorders, afflicting a high proportion of military casualties and veterans. The condition became central to the concerns of several psychological fields, from psychoanalysis to Pavlovian psychology. This paper reconstructs the efforts of Chicago psychiatrist Jules Masserman to study neurosis in the laboratory during the 1940s and 1950s. Masserman used Pavlovian techniques in a bid to subject this central psychoanalytic subject to disciplined scientific experimentation. More generally, his project was an effort to bolster the legitimacy of psychoanalysis as a human science by articulating a convergence of psychoanalytic categories across multiple species. Masserman sought to orchestrate a convergence of psychological knowledge between fields that were often taken to be irreconcilable. A central focus of this paper is the role of moving images in this project, not only as a means of recording experimental data but also as a rhetorical device. The paper argues that for Masserman film played an important role in enabling scientific observers (and then subsequent viewers) to see agency and emotion in the animals they observed. PMID:26903373

  3. Neuromorphic atomic switch networks.

    Directory of Open Access Journals (Sweden)

    Audrius V Avizienis

    Full Text Available Efforts to emulate the formidable information processing capabilities of the brain through neuromorphic engineering have been bolstered by recent progress in the fabrication of nonlinear, nanoscale circuit elements that exhibit synapse-like operational characteristics. However, conventional fabrication techniques are unable to efficiently generate structures with the highly complex interconnectivity found in biological neuronal networks. Here we demonstrate the physical realization of a self-assembled neuromorphic device which implements basic concepts of systems neuroscience through a hardware-based platform comprised of over a billion interconnected atomic-switch inorganic synapses embedded in a complex network of silver nanowires. Observations of network activation and passive harmonic generation demonstrate a collective response to input stimulus in agreement with recent theoretical predictions. Further, emergent behaviors unique to the complex network of atomic switches and akin to brain function are observed, namely spatially distributed memory, recurrent dynamics and the activation of feedforward subnetworks. These devices display the functional characteristics required for implementing unconventional, biologically and neurally inspired computational methodologies in a synthetic experimental system.

  4. Engagement processes in model programs for community reentry from prison for people with serious mental illness.

    Science.gov (United States)

    Angell, Beth; Matthews, Elizabeth; Barrenger, Stacey; Watson, Amy C; Draine, Jeffrey

    2014-01-01

    Linking prisoners with mental illness with treatment following release is critical to preventing recidivism, but little research exists to inform efforts to engage them effectively. This presentation compares the engagement process in two model programs, each representing an evidence-based practice for mental health which has been adapted to the context of prison reentry. One model, Forensic Assertive Community Treatment (FACT), emphasizes a long-term wrap-around approach that seeks to maximize continuity of care by concentrating all services within one interdisciplinary team; the other, Critical Time Intervention (CTI), is a time-limited intervention that promotes linkages to outside services and bolsters natural support systems. To compare engagement practices, we analyze data from two qualitative studies, each conducted in a newly developed treatment program serving prisoners with mental illness being discharged from prisons to urban communities. Findings show that the working relationship in reentry services exhibits unique features and is furthered in both programs by the use of practitioner strategies of engagement, including tangible assistance, methods of interacting with consumers, and encouragement of service use via third parties such as families and parole officers. Nevertheless, each program exhibited distinct cultures and rituals of reentry that were associated with fundamental differences in philosophy and differences in resources available to each program. PMID:24650496

  5. Independent Domestication of Two Old World Cotton Species.

    Science.gov (United States)

    Renny-Byfield, Simon; Page, Justin T; Udall, Joshua A; Sanders, William S; Peterson, Daniel G; Arick, Mark A; Grover, Corrinne E; Wendel, Jonathan F

    2016-01-01

    Domesticated cotton species provide raw material for the majority of the world's textile industry. Two independent domestication events have been identified in allopolyploid cotton, one in Upland cotton (Gossypium hirsutum L.) and the other to Egyptian cotton (Gossypium barbadense L.). However, two diploid cotton species, Gossypium arboreum L. and Gossypium herbaceum L., have been cultivated for several millennia, but their status as independent domesticates has long been in question. Using genome resequencing data, we estimated the global abundance of various repetitive DNAs. We demonstrate that, despite negligible divergence in genome size, the two domesticated diploid cotton species contain different, but compensatory, repeat content and have thus experienced cryptic alterations in repeat abundance despite equivalence in genome size. Evidence of independent origin is bolstered by estimates of divergence times based on molecular evolutionary analysis of f7,000 orthologous genes, for which synonymous substitution rates suggest that G. arboreum and G. herbaceum last shared a common ancestor approximately 0.4-2.5 Ma. These data are incompatible with a shared domestication history during the emergence of agriculture and lead to the conclusion that G. arboreum and G. herbaceum were each domesticated independently. PMID:27289095

  6. Instilling professionalism in the nuclear industry

    International Nuclear Information System (INIS)

    The American nuclear industry has implemented many technical changes in the past TMI decade. Equipment and facilities have been improved, procedures have been rewritten and refined, and operational personnel have bolstered their technical expertise. This paper reports that to place an increased focus upon professional -- the attitude, demeanor, and conscientiousness with which everyone conduct their jobs --- Westinghouse implemented the Conduct of Operations training program at the Department of Energy's (DOE) Waste Isolation Pilot Plant (WIPP). The program began by involving plant operations personnel in an intensive one-day training session using case studies to emphasize that it is people who determine the safety and effectiveness of our work environment. The case studies made it apparent that the human element is the factor common in all of these incidents. And, in these cases, when people became too removed from and/or complacent to automation, tragedy resulted. Finally, several organizations were explored in which a positive work culture and ethic is imbued so deeply and completely within the work force that it would be unthinkable to oppose the culture. Also, during the seminar session, work groups compiled their goals and values for good conduct of operations. In particular, each work group listed its standards for good conduct of operations as well as those factors necessary in the working environment to achieve their standard

  7. search.bioPreprint: a discovery tool for cutting edge, preprint biomedical research articles [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Carrie L. Iwema

    2016-07-01

    Full Text Available The time it takes for a completed manuscript to be published traditionally can be extremely lengthy. Article publication delay, which occurs in part due to constraints associated with peer review, can prevent the timely dissemination of critical and actionable data associated with new information on rare diseases or developing health concerns such as Zika virus. Preprint servers are open access online repositories housing preprint research articles that enable authors (1 to make their research immediately and freely available and (2 to receive commentary and peer review prior to journal submission. There is a growing movement of preprint advocates aiming to change the current journal publication and peer review system, proposing that preprints catalyze biomedical discovery, support career advancement, and improve scientific communication. While the number of articles submitted to and hosted by preprint servers are gradually increasing, there has been no simple way to identify biomedical research published in a preprint format, as they are not typically indexed and are only discoverable by directly searching the specific preprint server websites. To address this issue, we created a search engine that quickly compiles preprints from disparate host repositories and provides a one-stop search solution. Additionally, we developed a web application that bolsters the discovery of preprints by enabling each and every word or phrase appearing on any web site to be integrated with articles from preprint servers. This tool, search.bioPreprint, is publicly available at http://www.hsls.pitt.edu/resources/preprint.

  8. Incomplete Markets and Imperfect Institutions: Some Challenges Posed by Trust for Contemporary Health Care and Health Policy.

    Science.gov (United States)

    Schlesinger, Mark; Gray, Bradford H

    2016-08-01

    As contemporary health policy promotes evidence-based practices using targeted incentives, policy makers may lose track of vital aspects of care that are difficult to measure. For more than a half century, scholars have recognized that these latter aspects play a crucial role in high-quality care and equitable health system performance but depend on the potentially frail reed of providers' trustworthiness: that is, their commitment to facets and outcomes of care not easily assessed by external parties. More recently, early experience with pay for performance in health settings suggests that enhancing financial rewards for the measurable undermines providers' commitment to the unmeasurable, degrading the trustworthiness of their practices. Reformers have looked to revised professional norms or reorganized practice arrangements to bolster the intrinsic motivations required for trustworthiness. We suggest here that these responses are likely to prove inadequate. We propose that they be complemented by a renewed policy-making commitment to nonprofit ownership among health care providers, insurers, and integrated delivery systems. We identify some of the concerns raised in the past with ownership-based policies and propose a set of responses. If these are pursued in combination, they hold the promise of a sustainable ownership-based policy reform for the United States. PMID:27127254

  9. Identifying the Importance of Software Reuse in COCOMO81, COCOMOII

    Directory of Open Access Journals (Sweden)

    J.N.V.R Swarup Kumar

    2009-11-01

    Full Text Available Software project management is an interpolation of project planning, project monitoring and project termination. The substratal goals of planning are to scout for the future, to diagnose the attributes that are essentially done for the consummation of the project successfully, animate the scheduling and allocate resources for the attributes. Software cost estimation is a vital role in preeminent software project decisions such as resource allocation and bidding. This paper articulates the conventional overview of software cost estimation modus operandi available. The cost, effort estimates of software projects done by the various companies are congregated, the results are segregated with the present cost models and the MRE (Mean Relative Error is enumerated. We have administered the historical data to COCOMO 81, COCOMOII model and identified that the stellar predicament is that no cost model gives the exact estimate of a software project. This is due to the fact that a lot of productivity factors are not contemplated in estimation process. The vital dilemma we identified is that “software reuse” is being eclipsed although most of the contemporary software projects are based on object oriented development where no component is made from scratch (Inheritance. By using the principal of software reuse the ROI (Return of Investment is also bolstered for the companies. So further research exposure is in “software Reuse” and Reuse software cost estimation model.

  10. US firms still restructuring, cutting costs under oil price uncertainty

    International Nuclear Information System (INIS)

    Despite more than a decade of downsizing, continuing uncertainty in oil markets is forcing US petroleum companies into another round of cutting and restructuring operations. Wellhead gas prices in the US, although still volatile, in the past 2 years have risen to levels adequate to allow profits for most producers in that sector. Higher gas reserves valuations have strengthened producers' overall balance sheets. But the slide in oil prices from the middle of fourth quarter 1993 until the recent upswing the past month has withered producers' financial performances and reserves values. With little prospect of significantly higher oil prices anytime soon, US companies feel they have little choice but to continue pressing cost cutting moves in order to sustain profits in the near term while at the same time earnings a higher return on investment in the long term. Petroleum company executives are overlooking almost no operating or investment strategy thought capable of bolstering the bottom line. Because no two US oil and gas companies are alike, each profit protection plan is a unique mix of similar solutions. Oil and gas production companies most often try to lower operating costs by vigorously selling noncore properties or business units and reducing staff. The paper discusses measures taken by oil and gas companies to lower costs

  11. Albanian legal framework on Factoring contract

    Directory of Open Access Journals (Sweden)

    Anjeza Liçenji

    2013-07-01

    Full Text Available Factoring contract is a new phenomenon, compared to earlier forms of commerce in juridical circulation. Factoring is a method used by a firm to obtain cash when available cash balance, held by the firm, is insufficient to meet current obligations, and accommodate its other cash needs, such as new orders or contracts. The use of factoring to obtain the cash, needed to accommodate the firm’s immediate cash needs, will allow the firm to maintain a smaller ongoing cash balance. By reducing the size of its cash balances, more money becomes available for investment in the firm’s growth. A company sells its invoices at discount to their face value when it calculates that it will be better off proceeding to bolster its own growth than it would be by effectively functioning as its “customer’s bank”. Many businesses have cash flow that varies. A business might have a relatively large cash flow in one period, as well as a relatively small cash flow in another period. Because of this, firms find it necessary to both keep a cash balance on hand, and use such methods as factoring, in order to enable them to cover their short term cash needs in those periods in which these needs exceed cash flow.

  12. The study of perceived stress, coping strategy and self-efficacy of Chinese undergraduate nursing students in clinical practice.

    Science.gov (United States)

    Zhao, Fang-Fang; Lei, Xiao-Ling; He, Wei; Gu, Yan-Hong; Li, Dong-Wen

    2015-08-01

    The aim of the study was to explore the coping strategy and the effects of self-efficacy of Chinese undergraduate nursing students when they face the stress in clinical practice. Convenience sampling was used to recruit undergraduate nursing students in Mainland China who have practiced 3 months in hospitals in their final college year. Self-report questionnaires including demographics, Perceived Stress Scale, coping behaviour inventory and Generalized Self-Efficacy Scale were collected. The results showed that during clinical practice, assignments and workload were the most common stress to students; transference was the most frequently used coping strategy by students. Self-efficacy not only had a positive main effect in predicting the frequency of use of staying optimistic and problem solving strategies but also moderated the effects of stress from taking care of patients on transference strategy, as well as stress from assignments and workload on problem solving strategy. It is essential to bolster the students' self-efficacy to reduce stress and adopt positively the coping strategies during clinical practice. PMID:24750234

  13. Report on the first Quadrennial Technology Review (QTR)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-09-30

    Access to clean, affordable, secure, and reliable energy has been a cornerstone of America’s economic growth. The Nation’s systems that produce, store, transmit, and use energy are falling short of U.S. needs. Maintaining energy security, bolstering U.S. competitiveness, and mitigating the environmental impacts of energy are long-­standing challenges. Governments, consumers, and the private sector have worked for decades to address these challenges, yet they remain among the Nation’s most pressing issues. President Obama has articulated broad national energy goals for reducing U.S. dependence on oil, reducing pollution, and investing in research and development (R&D) for clean-­energy technologies in the United States to create jobs. These include: Reducing oil imports by one-third by 2025; Supporting the deployment of 1 million electric vehicles on the road by 2015; Making non-residential buildings 20% more energy efficient by 2020; Deriving 80% of America's electricity from clean-energy sources by 2035; and Reducing greenhouse gas emissions by 175 by 2020 and 83% of 2050, from a 2005 baseline.

  14. Graphic warning labels on plain cigarette packs: will they make a difference to adolescents?

    Science.gov (United States)

    McCool, Judith; Webb, Lisa; Cameron, Linda D; Hoek, Janet

    2012-04-01

    Graphic warning labels and plain cigarette packaging are two initiatives developed to increase quit behaviour among smokers. Although a little is known about how adolescents interpret graphic warning labels, very few studies have examined how plain cigarette packaging would affect adolescents' perceptions of cigarette smoking and smoking behaviour. We explored how teens interpret and respond to graphic warning labels and the plain packaging of cigarettes, to assess the potential these strategies may offer in deterring smoking initiation. Twelve focus group interviews with a sample of 80 14-16 year old students from a diverse range of schools in Auckland, New Zealand were undertaken between June and August 2009. Textual analysis revealed that graphic warning labels may influence adolescents by reiterating a negative image of smokers. Graphic warning on a plain cigarette pack increased the attention paid to graphic warning labels and the overall perceptions of harm caused by cigarette smoking, and reduced the social appeal of cigarette smoking. This research offers evidence on how adolescents are appraising and interpreting graphic warning labels, and explores how dominant appraisals may affect the role graphic warning labels play in preventing smoking. Not only would plain cigarette packaging enhance the salience and impact of graphic warning labels, but it would potentially bolster the overall message that cigarette smoking is harmful. In the context of a comprehensive tobacco control programme, graphic warning labels on plain cigarette packaging present an explicit message about the risks (to health and image) associated with cigarette smoking. PMID:22385817

  15. La partialité par les projets

    Directory of Open Access Journals (Sweden)

    Sarah Stroud

    2008-02-01

    Full Text Available This paper investigates how we can most effectively argue that partiality toward certain people and not others is morally permissible. Philosophers who strongly insist that morality must leave room for partiality have not made explicit their basis for this conclusion; the present paper comparatively assesses a variety of possible argument strategies which could be deployed in this regard. One promising strategy exploits the acknowledged force of the argument from “the personal point of view,” here interpreted as referring specifically to an agent’s projects. If moral demands must be tempered in light of the special significance to an agent of his own projects, then perhaps the agent’s partial attachments to other people should also receive a measure of protection from impartial moral claims. The case is bolstered by noting the ubiquity of plural or collective agency in contexts of close personal relations: often the two (or more agents in such relationships together pursue joint projects and even constitute a plural agent. This approach does justify special moral treatment of one’s co-agents, although it does not match our initial conception of partiality in all respects.

  16. Wind energy: Past experience and future

    International Nuclear Information System (INIS)

    Reductions in the cost of producing wind energy are helping to make this renewable energy source competitive with conventional energy sources. The market for this type of energy in Italy, however, hasn't yet gained a foothold even though close examination of Italy's geomorphology reveals that this country is in fact endowed with many areas having good potential for wind power production. This paper discusses the measures to be taken to bolster wind energy commercialization efforts in Italy. It provides a brief assessment of the current state of wind power technology, national and international market trends, and the directions being taken by other national governments to promote wind turbine manufacturing industries and applications. The comparative analysis indicates that in order to have this energy source alternative taken seriously as an economically viable energy option in Italy, greater financial assistance should be given to local manufacturers involved in commercialization efforts. In addition, a suitable rate structure should be created favouring wind power by taking into account cost benefits afforded by this renewable energy source in terms of reduced air pollution, as well as, reduced national dependency on foreign energy imports

  17. “Recovering our Stories”: A Small Act of Resistance

    Directory of Open Access Journals (Sweden)

    Lucy Costa

    2012-10-01

    Full Text Available This paper describes a community event organized in response to the appropriation and overreliance on the psychiatric patient “personal story” within mental health organizations. The sharing of experiences through stories by individuals who self-identify as having “lived experience” has been central to the history of organizing for change in and outside of the psychiatric system. However, in the last decade, personal stories have increasingly been used by the psychiatric system to bolster research, education, and fundraising interests. We explore how personal stories from consumer/survivors have been harnessed by mental health organizations to further their interests and in so doing have shifted these narrations from “agents of change” towards one of “disability tourism” or “patient porn.” We mark the ethical dilemmas of narrative cooptation and consumption, and query how stories of resistance can be reclaimed not as personal recovery narratives but rather as a tool for socio-political change.

  18. Exploiting dimensionality and defect mitigation to create tunable microwave dielectrics

    Science.gov (United States)

    Lee, Che-Hui; Orloff, Nathan D.; Birol, Turan; Zhu, Ye; Goian, Veronica; Rocas, Eduard; Haislmaier, Ryan; Vlahos, Eftihia; Mundy, Julia A.; Kourkoutis, Lena F.; Nie, Yuefeng; Biegalski, Michael D.; Zhang, Jingshu; Bernhagen, Margitta; Benedek, Nicole A.; Kim, Yongsam; Brock, Joel D.; Uecker, Reinhard; Xi, X. X.; Gopalan, Venkatraman; Nuzhnyy, Dmitry; Kamba, Stanislav; Muller, David A.; Takeuchi, Ichiro; Booth, James C.; Fennie, Craig J.; Schlom, Darrell G.

    2013-10-01

    The miniaturization and integration of frequency-agile microwave circuits--relevant to electronically tunable filters, antennas, resonators and phase shifters--with microelectronics offers tantalizing device possibilities, yet requires thin films whose dielectric constant at gigahertz frequencies can be tuned by applying a quasi-static electric field. Appropriate systems such as BaxSr1-xTiO3 have a paraelectric-ferroelectric transition just below ambient temperature, providing high tunability. Unfortunately, such films suffer significant losses arising from defects. Recognizing that progress is stymied by dielectric loss, we start with a system with exceptionally low loss--Srn+1TinO3n+1 phases--in which (SrO)2 crystallographic shear planes provide an alternative to the formation of point defects for accommodating non-stoichiometry. Here we report the experimental realization of a highly tunable ground state arising from the emergence of a local ferroelectric instability in biaxially strained Srn+1TinO3n+1 phases with n>=3 at frequencies up to 125GHz. In contrast to traditional methods of modifying ferroelectrics--doping or strain--in this unique system an increase in the separation between the (SrO)2 planes, which can be achieved by changing n, bolsters the local ferroelectric instability. This new control parameter, n, can be exploited to achieve a figure of merit at room temperature that rivals all known tunable microwave dielectrics.

  19. Spectroscopy of Young Planetary Mass Candidates with Disks

    CERN Document Server

    Jayawardhana, R; Jayawardhana, Ray; Ivanov, Valentin D.

    2006-01-01

    It is now well established that many young brown dwarfs exhibit characteristics similar to classical T Tauri stars, including infrared excess from disks and emission lines related to accretion. Whether the same holds true for even lower mass objects, namely those near and below the Deuterium-burning limit, is an important question. Here we present optical spectra of six isolated planetary mass candidates in Chamaeleon II, Lupus I and Ophiuchus star-forming regions, recently identified by Allers and collaborators to harbor substantial mid-infrared excesses. Our spectra, from ESO's Very Large Telescope and New Technology Telescope, show that four of the targets have spectral types in the ~M9-L1 range, and three of those also exhibit H_alpha. Their luminosities are consistent with masses of ~5-15 M_{Jupiter} according to models of Chabrier, Baraffe and co-workers, thus placing these four objects among the lowest mass brown dwarfs known to be surrounded by circum-sub-stellar disks. Our findings bolster the idea t...

  20. Use screening tools, partnerships to improve identification, care of victims of IPV.

    Science.gov (United States)

    2015-02-01

    While accrediting organizations require hospitals to put protocols in place to deal with intimate partner violence (IPV), research shows that the problem is often left uncovered in women who present for care in busy EDs. One study suggests that as much as 72% of women with a history of IPV are not identified when they visit the ED for medical issues. Experts are hopeful that recent publicity about IPV will heighten awareness and improve screening for the problem. Experts say providers are often reluctant to ask questions about IPV, either because they are unsure of how to respond or they lack ready access to resources for referral. When screening for IPV, it is important to ask behavior-specific questions so that there is no room for misinterpretation. To bolster the emergency response to incidents of IPV, hospitals need to seek out and nurture relationships with community organizations that can serve as referral sources to victims. Experts say providers need to consider the possibility of traumatic brain injury in women who present with head and/or facial injuries. PMID:25688415

  1. The Contribution of and Uncertainty Associated with Self-Multiplication when Assaying Plutonium in Waste by Passive Neutron Coincidence Counting

    International Nuclear Information System (INIS)

    When Pu is present in waste items as lumps, the Reals neutron coincidence signal may be bolstered by virtue of self induced fission events. This gives rise to a positive bias to the assay result and leads to a one sided contribution to the total measurement uncertainty. In the general it is not feasible to determine to magnitude of this effect experimentally and allowance for it must therefore be estimated using separate ad hoc rules. In this paper we to develop a simple model for the self-multiplication enhancement in small lumps allowing the importance of the effect in waste assay to be quantified. In addition, an approach is suggested for how to propagate an uncertainty contribution in to the final result. In conclusion: By introducing a generic scheme we have taken the first pragmatic steps to accounting for multiplication effects in the TMU in the determination of Pu-240 eff-mass by PNCC in waste. We have used a simple physical model to derive the underlying relationships needed. A first order expression suitable for small, dense lumps was set out, primarily for instructive reasons, but this is not a restriction of the method. The method is readily scaleable to material of different isotopic composition, density and a. Numerical parameters suitable for practical applications have been established and we feel the approach is fit for the intended purpose reflecting operational experiences and the general state of knowledge of waste items. (authors)

  2. Light: A Spectrum of Utility, the 2014-2015 Society of Physics Students Science Outreach Catalyst Kit

    Science.gov (United States)

    Sellers, Mark; Louis-Jean, Kearns; Society of Physics Students Collaboration; National Institute of Standards; Technology Collaboration

    2015-03-01

    The Science Outreach Catalyst Kit (SOCK) is a set of activities and demonstrations designed to bolster the outreach programs of undergraduate Society of Physics Students (SPS) chapters, creating the framework for a lasting outreach program. Targeted for students ranging from kindergarten to high school, the SOCK allows students to actively engage in hands-on activities that teach them scientific skills and allow them to exercise their natural curiosity. The 2014-2015 SOCK united themes from the 2014 International Year of Crystallography and the 2015 International Year of Light to explore how light is used as a tool every day. This presentation will discuss the contents of the SOCK, which contains a large assortment of materials, such as diffraction glasses, polarizers, ultraviolet flashlights, etc. and describe the research and development of the activities. Each activity explores a different light phenomenon, such as diffraction, polarization, reflection, or fluorescence. These activities will promote critical thinking and analysis of data. This work was supported by the Society of Physics Students summer intern program and by the National Institute of Standards and Technology.

  3. A New Spin on Photoemission Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Jozwiak, Chris [Univ. of California, Berkeley, CA (United States)

    2008-12-01

    The electronic spin degree of freedom is of general fundamental importance to all matter. Understanding its complex roles and behavior in the solid state, particularly in highly correlated and magnetic materials, has grown increasingly desirable as technology demands advanced devices and materials based on ever stricter comprehension and control of the electron spin. However, direct and efficient spin dependent probes of electronic structure are currently lacking. Angle Resolved Photoemission Spectroscopy (ARPES) has become one of the most successful experimental tools for elucidating solid state electronic structures, bolstered by-continual breakthroughs in efficient instrumentation. In contrast, spin-resolved photoemission spectroscopy has lagged behind due to a lack of similar instrumental advances. The power of photoemission spectroscopy and the pertinence of electronic spin in the current research climate combine to make breakthroughs in Spin and Angle Resolved Photoemission Spectroscopy (SARPES) a high priority . This thesis details the development of a unique instrument for efficient SARPES and represents a radical departure from conventional methods. A custom designed spin polarimeter based on low energy exchange scattering is developed, with projected efficiency gains of two orders of magnitude over current state-of-the-art polarimeters. For energy analysis, the popular hemispherical analyzer is eschewed for a custom Time-of-Flight (TOF) analyzer offering an additional order of magnitude gain in efficiency. The combined instrument signifies the breakthrough needed to perform the high resolution SARPES experiments necessary for untangling the complex spin-dependent electronic structures central to today's condensed matter physics.

  4. Immune Modulation by Chemotherapy or Immunotherapy to Enhance Cancer Vaccines

    Energy Technology Data Exchange (ETDEWEB)

    Weir, Genevieve M. [Suite 411, 1344 Summer St., Immunovaccine Inc., Halifax, NS, B3H 0A8 (Canada); Room 11-L1, Sir Charles Tupper Building, Department of Microbiology & Immunology, Dalhousie University, 5850 College St, Halifax, NS, B3H 1X5 (Canada); Liwski, Robert S. [Room 11-L1, Sir Charles Tupper Building, Department of Microbiology & Immunology, Dalhousie University, 5850 College St, Halifax, NS, B3H 1X5 (Canada); Room 206E, Dr. D. J. Mackenzie Building, Department of Pathology, Dalhousie University, 5788 University Avenue, Halifax, NS, B3H 2Y9 (Canada); Mansour, Marc [Suite 411, 1344 Summer St., Immunovaccine Inc., Halifax, NS, B3H 0A8 (Canada)

    2011-08-05

    Chemotherapy has been a mainstay in cancer treatment for many years. Despite some success, the cure rate with chemotherapy remains unsatisfactory in some types of cancers, and severe side effects from these treatments are a concern. Recently, understanding of the dynamic interplay between the tumor and immune system has led to the development of novel immunotherapies, including cancer vaccines. Cancer vaccines have many advantageous features, but their use has been hampered by poor immunogenicity. Many developments have increased their potency in pre-clinical models, but cancer vaccines continue to have a poor clinical track record. In part, this could be due to an inability to effectively overcome tumor-induced immune suppression. It had been generally assumed that immune-stimulatory cancer vaccines could not be used in combination with immunosuppressive chemotherapies, but recent evidence has challenged this dogma. Chemotherapies could be used to condition the immune system and tumor to create an environment where cancer vaccines have a better chance of success. Other types of immunotherapies could also be used to modulate the immune system. This review will discuss how immune modulation by chemotherapy or immunotherapy could be used to bolster the effects of cancer vaccines and discuss the advantages and disadvantages of these treatments.

  5. Proximity of snacks to beverages increases food consumption in the workplace: A field study.

    Science.gov (United States)

    Baskin, Ernest; Gorlin, Margarita; Chance, Zoë; Novemsky, Nathan; Dhar, Ravi; Huskey, Kim; Hatzis, Michelle

    2016-08-01

    In an effort to bolster employee satisfaction, many employers provide free snacks at the office. Unfortunately, keeping employees happy can conflict with the goal of keeping them healthy, since increased snacking at work can contribute to overeating and obesity. Building on the growing body of research in choice architecture, we tested one factor that might influence snack consumption without impacting satisfaction: the relative distance between snacks and beverages. In a large field study at Google, we measured snack consumption when snacks were closer to or farther from beverages. We found that employees who used the beverage station closer to the snack station were more likely to take a snack- the likelihood of snacking increased from 12% to 23% for men and from 13% to 17% for women when the beverage station closest to the snack station was used. These results imply that employers and even families could reduce snack consumption easily, cheaply, and without backlash, by increasing the relative distance between beverages and snacks. PMID:27112315

  6. Online and Social Media Suicide Prevention Interventions for Young People: A Focus on Implementation and Moderation

    Science.gov (United States)

    Rice, Simon; Robinson, Jo; Bendall, Sarah; Hetrick, Sarah; Cox, Georgina; Bailey, Eleanor; Gleeson, John; Alvarez-Jimenez, Mario

    2016-01-01

    Objective: Suicide remains a major global public health issue for young people. The reach and accessibility of online and social media-based interventions herald a unique opportunity for suicide prevention. To date, the large body of research into suicide prevention has been undertaken atheoretically. This paper provides a rationale and theoretical framework (based on the interpersonal theory of suicide), and draws on our experiences of developing and testing online and social media-based interventions. Method: The implementation of three distinct online and social media-based intervention studies, undertaken with young people at risk of suicide, are discussed. We highlight the ways that these interventions can serve to bolster social connectedness in young people, and outline key aspects of intervention implementation and moderation. Results: Insights regarding the implementation of these studies include careful protocol development mindful of risk and ethical issues, establishment of suitably qualified teams to oversee development and delivery of the intervention, and utilisation of key aspects of human support (i.e., moderation) to encourage longer-term intervention engagement. Conclusions: Online and social media-based interventions provide an opportunity to enhance feelings of connectedness in young people, a key component of the interpersonal theory of suicide. Our experience has shown that such interventions can be feasibly and safely conducted with young people at risk of suicide. Further studies, with controlled designs, are required to demonstrate intervention efficacy. PMID:27274743

  7. Gravitational anomalies and one-dimensional behavior of black holes

    Energy Technology Data Exchange (ETDEWEB)

    Majhi, Bibhas Ranjan [Indian Institute of Technology Guwahati, Department of Physics, Guwahati, Assam (India)

    2015-12-15

    It has been pointed out by Bekenstein and Mayo that the behavior of the black hole's entropy or information flow is similar to information flow through one-dimensional channel. Here I analyze the same issue with the use of gravitational anomalies. The rate of the entropy change (S) and the power (P) of the Hawking emission are calculated from the relevant components of the anomalous stress tensor under the Unruh vacuum condition. I show that the dependence of S on the power is S ∝ P{sup 1/2}, which is identical to that for the information flow in a one-dimensional system. This is established by using the (1+1)-dimensional gravitational anomalies first. Then the fact is further bolstered by considering the (1+3)-dimensional gravitational anomalies. It is found that, in the former case, the proportionality constant is exactly identical to the one-dimensional situation, known as Pendry's formula, while in the latter situation its value decreases. (orig.)

  8. Iridium-Tin oxide solid-solution nanocatalysts with enhanced activity and stability for oxygen evolution

    Science.gov (United States)

    Li, Guangfu; Yu, Hongmei; Yang, Donglei; Chi, Jun; Wang, Xunying; Sun, Shucheng; Shao, Zhigang; Yi, Baolian

    2016-09-01

    Addressing major challenges from the material cost, efficiency and stability, it is highly desirable to develop high-performance catalysts for oxygen evolution reaction (OER). Herein we explore a facile surfactant-assisted approach for fabricating Irsbnd Sn (Ir/Sn = 0.6/0.4, by mol.) nano-oxide catalysts with good morphology control. Direct proofs from XRD and X-ray photoelectron spectra indicate hydrophilic triblock polymer (TBP, like Pluronic® F108) surfactant can boost the formation of stable solid-solution structure. With the TBP hydrophilic and block-length increase, the fabricated Irsbnd Sn oxides undergoing the rod-to-sphere transition obtain the relatively lower crystallization, decreased crystallite size, Ir-enriched surface and incremental available active sites, all of which can bolster the OER activity and stability. Meanwhile, it is observed that the coupled Ir oxidative etching takes a crucial role in determining the material structure and performance. Compared with commercial Ir black, half-cell tests confirm F108-assistant catalysts with over 40 wt% Ir loading reduction show 2-fold activity enhancement as well as significant stability improvement. The lowest cell voltage using 0.88 mg cm-2 Ir loading is only 1.621 V at 1000 mA cm-2 and 80 °C with a concomitant energy efficiency of 75.8% which is beyond the DOE 2017 efficiency target of 74%.

  9. A dual-systems perspective on addiction: contributions from neuroimaging and cognitive training.

    Science.gov (United States)

    McClure, Samuel M; Bickel, Warren K

    2014-10-01

    Dual-systems theories explain lapses in self-control in terms of a conflict between automatic and deliberative modes of behavioral control. Numerous studies have now tested whether the brain areas that control behavior are organized in a manner consistent with dual-systems models. Brain regions directly associated with the mesolimbic dopamine system, the nucleus accumbens and ventromedial prefrontal cortex in particular, capture some of the features assumed by automatic processing. Regions in the lateral prefrontal cortex are more closely linked to deliberative processing and the exertion of self-control in the suppression of impulses. While identifying these regions crudely supports dual-systems theories, important modifications to what constitutes automatic and deliberative behavioral control are also suggested. Experiments have identified various means by which automatic processes may be sculpted. Additional work decomposes deliberative processes into component functions such as generalized working memory, reappraisal of emotional stimuli, and prospection. The importance of deconstructing dual-systems models into specific cognitive processes is clear for understanding and treating addiction. We discuss intervention possibilities suggested by recent research, and focus in particular on cognitive training approaches to bolster deliberative control processes that may aid quit attempts. PMID:25336389

  10. U.S. industry to hold 1994 spending at the 1993 level

    International Nuclear Information System (INIS)

    A sharp cut in spending on pipelines will hold US petroleum industry budgets at about 1993 levels for domestic projects this year. Excluding pipeline outlays, industry spending for capital and exploration items will advance. Oil and Gas Journal's annual budget survey shows US companies plan to spend $31.3 billion on US projects in 1994, down only 0.7% from 1993. Spending last year was down by the same percentage from 1992's $31.7 billion. Total outlays, excluding pipelines, well be $28.9 billion, up 5.8% from 1993. In 1993 spending excluding pipelines was $27.3 billion, down 1.2% from 1992. Industry's total spending hit a high of $83 billion in 1981. It then fell to the recent low of $25.2 billion in 1987. Adjusted for inflation, spending in 1994 will be the lowest since 1987. A sharp drop in drilling lowered upstream outlays during the past several years. At the same time, spending for upgrades, renovation, environmental compliance, marketing, and transportation bolstered downstream budgets. E and P spending in 1994 will increase 6.2% from the 1993 level, moving up to $14.8 billion. Refining capital spending will inch up 0.9% to $5.4 billion for 1994

  11. Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

    Science.gov (United States)

    Eruslanov, Evgeniy B.; Bhojnagarwala, Pratik S.; Quatromoni, Jon G.; Stephen, Tom Li; Ranganathan, Anjana; Deshpande, Charuhas; Akimova, Tatiana; Vachani, Anil; Litzky, Leslie; Hancock, Wayne W.; Conejo-Garcia, José R.; Feldman, Michael; Albelda, Steven M.; Singhal, Sunil

    2014-01-01

    Infiltrating inflammatory cells are highly prevalent within the tumor microenvironment and mediate many processes associated with tumor progression; however, the contribution of specific populations remains unclear. For example, the nature and function of tumor-associated neutrophils (TANs) in the cancer microenvironment is largely unknown. The goal of this study was to provide a phenotypic and functional characterization of TANs in surgically resected lung cancer patients. We found that TANs constituted 5%–25% of cells isolated from the digested human lung tumors. Compared with blood neutrophils, TANs displayed an activated phenotype (CD62LloCD54hi) with a distinct repertoire of chemokine receptors that included CCR5, CCR7, CXCR3, and CXCR4. TANs produced substantial quantities of the proinflammatory factors MCP-1, IL-8, MIP-1α, and IL-6, as well as the antiinflammatory IL-1R antagonist. Functionally, both TANs and neutrophils isolated from distant nonmalignant lung tissue were able to stimulate T cell proliferation and IFN-γ release. Cross-talk between TANs and activated T cells led to substantial upregulation of CD54, CD86, OX40L, and 4-1BBL costimulatory molecules on the neutrophil surface, which bolstered T cell proliferation in a positive-feedback loop. Together our results demonstrate that in the earliest stages of lung cancer, TANs are not immunosuppressive, but rather stimulate T cell responses. PMID:25384214

  12. A 26-year Composite Stable Isotope Record of Precipitation, Humidity and El Niño in the Spines of Saguaro Cactus, Carnegiea gigantea.

    Science.gov (United States)

    English, N. B.; Dettman, D. L.; Williams, D. G.

    2008-12-01

    Seasonal cycles of rainfall and humidity are recorded by stable isotopes in the spines of columnar cactuses. Multi-decadal δ18O and δ13C records of spine series from five saguaro cactuses, dated using bomb radiocarbon and semi-annual variations in δ13C, demonstrate the reproducibility of a climate signal. For δ18O and δ13C, the expressed population signal between 1980 and 2006 is 0.68 and 0.66, respectively, but 0.76 and 0.59 between 1980 and 1997, suggesting that age/height related effects are present in isotopic spine series. Composite δ18O and δ13C records constructed from five spine series show significant relationships to external climate forcing. Once dating errors are corrected, mean annual spine δ18O is negatively correlated with total annual precipitation (TAP) from November through October (P 2‰) in the maximum annual spine δ18O are positively correlated with the Southern Oscillation Index (P < 0.01). We hypothesize these decreases are caused by El Niño enhanced winter rainfall. While less significant, minimum annual δ13C is negatively correlated with TAP (P < 0.05) and mean nighttime VPD (P < 0.05). These results bolster proposed mechanistic models of isotopic variation in the spines of columnar cactuses and demonstrate the use of isotopic spine series as climate proxies.

  13. Science Alive!: Connecting with Elementary Students through Science Exploration.

    Science.gov (United States)

    Raja, Aarti; Lavin, Emily Schmitt; Gali, Tamara; Donovan, Kaitlin

    2016-05-01

    A novel program called Science Alive! was developed by undergraduate faculty members, K-12 school teachers, and undergraduate students to enrich science, technology, engineering, and mathematics (STEM) literacy at community schools located near the university. The ultimate goal of the program is to bolster the scientific knowledge and appreciation of local area students and community members and serve as a model for similar programs. Through the program, we observed that elementary school students made gains toward learning their grade-level science curricula after a hands-on learning experience and had fun doing these hands-on activities. Through the program, undergraduate students, working with graduate students and alumni, build scientific learning modules using explanatory handouts and creative activities as classroom exercises. This helps better integrate scientific education through a collaborative, hands-on learning program. Results showed that elementary school students made the highest learning gains in their performance on higher-level questions related to both forces and matter as a result of the hands-on learning modules. Additionally, college students enjoyed the hands-on activities, would consider volunteering their time at such future events, and saw the service learning program as a benefit to their professional development through community building and discipline-specific service. The science modules were developed according to grade-level curricular standards and can be used year after year to teach or explain a scientific topic to elementary school students via a hands-on learning approach. PMID:27158309

  14. Bringing Back the Social Affordances of the Paper Memo to Aerospace Systems Engineering Work

    Science.gov (United States)

    Davidoff, Scott; Holloway, Alexandra

    2014-01-01

    Model-based systems engineering (MBSE) is a relatively new field that brings together the interdisciplinary study of technological components of a project (systems engineering) with a model-based ontology to express the hierarchical and behavioral relationships between the components (computational modeling). Despite the compelling promises of the benefits of MBSE, such as improved communication and productivity due to an underlying language and data model, we observed hesitation to its adoption at the NASA Jet Propulsion Laboratory. To investigate, we conducted a six-month ethnographic field investigation and needs validation with 19 systems engineers. This paper contributes our observations of a generational shift in one of JPL's core technologies. We report on a cultural misunderstanding between communities of practice that bolsters the existing technology drag. Given the high cost of failure, we springboard our observations into a design hypothesis - an intervention that blends the social affordances of the narrative-based work flow with the rich technological advantages of explicit data references and relationships of the model-based approach. We provide a design rationale, and the results of our evaluation.

  15. The Relationship of Self Esteem and Humor Styles in First Class Medical Students: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Soner Cakmak

    2015-12-01

    Material and Methods: Two hundred three medical students (107 males, 96 females were included this study. Self-esteem was measured with the Rosenberg Self Esteem Scale and humor style was measured with Humor Styles Questionnaire. Results: The rate of students who have mild or high self-esteem levels was 89.7%. In Humor Styles Questionnaire, the average scores of affiliative and self-enhancing humor were significantly higher than the average scores of aggressive and self-defeating humor. Male students were using humor, especially aggressive and self-defeating humor styles more commonly than female students. A positive correlation was found between self-esteem and affiliative and self-enhancing humor styles. Conclusion: The present study revealed a positive correlation between self-esteem and positive humor styles. There is a need to develop educational models that would bolster self-esteem and positive humor in medical students. [Cukurova Med J 2015; 40(4.000: 782-793

  16. Extending the Fermi - Swift Joint AGN Sample

    Science.gov (United States)

    Shrader, Chris R.; Macomb, D. J.

    2014-01-01

    The Swift BAT and the Fermi LAT each provide excellent sky coverage and have led to impressive compilations of extragalactic source catalogs. For the most part they sample separate AGN subpopulations - Swift the lower-luminosity and relatively nearby Seyfert galaxies while the Fermi sample is dominated by blazars and does not include any radio-quiet objects. The overlap between these samples is among the radio-loud subset of the Swift sample as has been discussed elsewhere in the literature. The observable properties at these two bands - flux and spectral indices - are not expected to be well correlated as they sample different portions of the synchrotron self-Compton (SSC) spectral energy distribution. In this contribution we consider an extension of the high-latitude Swift sample by relaxing the significance cut to less than 5 standard deviations and consider the overlap of that subsample with the Fermi AGN catalog. While such a threshold is generally inadvisable as it introduces the strong possibility of spurious detections, the objects of the overlapping sample which are detected at high significance in Fermi can be considered as reasonably high-confidence Swift detections. For example, there are 190 Swift sub-5-sigma Swift sources that have significance >2-sigma with Fermi counterparts, whereas we predict only ~5 due to statistical fluctuation. We also investigate any coincident INTEGRAL/IBIS observations to further bolster or diminish candidate Swift detections. We present our correlation analyses and offer interpretation in the context of the blazar sequence.

  17. EVA Skills Training

    Science.gov (United States)

    Parazynski, Scott

    2012-01-01

    Dr. Parazynski and a colleague from Extravehicular Activity (EVA), Robotics, & Crew Systems Operations (DX) worked closely to build the EVA Skills Training Program, and for the first time, defined the gold standards of EVA performance, allowing crewmembers to increase their performance significantly. As part of the program, individuals had the opportunity to learn at their own rate, taking additional water time as required, to achieve that level of performance. This focus on training to one's strengths and weaknesses to bolster them enabled the Crew Office and DX to field a much larger group of spacewalkers for the daunting "wall of EVA" required for the building and maintenance of the ISS. Parazynski also stressed the need for designers to understand the capabilities and the limitations of a human in a spacesuit, as well as opportunities to improve future generations of space. He shared lessons learned (how the Crew Office engaged in these endeavors) and illustrated the need to work as a team to develop these complex systems.

  18. From road to lab to math: the co-evolution of technological, regulatory, and organizational innovations for automotive crash testing.

    Science.gov (United States)

    Leonardi, Paul M

    2010-04-01

    Today, in the midst of economic crisis, senior executives at US automakers and influential industry analysts frequently reflect on the progression that safety testing has taken from the crude trials done on the road, to controlled laboratory experiments, and to today's complex math-based simulation models. They use stories of this seemingly linear and natural sequence to justify further investment in simulation technologies. The analysis presented in this paper shows that change in the structures of automakers' organizations co-evolved with regulations specifying who was at fault in vehicle impacts, how vehicles should be built to withstand the force of an impact, and how testing should be done to assure that vehicles met those requirements. Changes in the regulatory environment were bolstered by new theories about crash test dynamics and changing technologies with which to test those theories. Thus, as new technological and regulatory innovations co-evolved with innovations in organizational structuring, ideas about how to best conduct crash tests shifted and catalyzed new cycles of technological, regulatory, and organizational innovation. However, this co-evolutionary story tells us that the move from road to lab to math was not natural or linear as today's managerial rhetoric would have us believe. Rather, the logic of math-based simulation was the result of technological, regulatory and organizational changes that created an industry-wide ideology that supported the move toward math while making it appear natural within the shifting structure of the industry. PMID:20527322

  19. Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly.

    Science.gov (United States)

    Roessler, Erich; Pei, Wuhong; Ouspenskaia, Maia V; Karkera, Jayaprakash D; Veléz, Jorge Ivan; Banerjee-Basu, Sharmilla; Gibney, Gretchen; Lupo, Philip J; Mitchell, Laura E; Towbin, Jeffrey A; Bowers, Peter; Belmont, John W; Goldmuntz, Elizabeth; Baxevanis, Andreas D; Feldman, Benjamin; Muenke, Maximilian

    2009-01-01

    The cyclopic and laterality phenotypes in model organisms linked to disturbances in the generation or propagation of Nodal-like signals are potential examples of similar impairments resulting in birth defects in humans. However, the types of gene mutation(s) and their pathogenetic combinations in humans are poorly understood. Here we describe a mutational analysis of the human NODAL gene in a large panel of patients with phenotypes compatible with diminished NODAL ligand function. Significant reductions in the biological activity of NODAL alleles are detected among patients with congenital heart defects (CHD), laterality anomalies (e.g. left-right mis-specification phenotypes), and only rarely holoprosencephaly (HPE). While many of these NODAL variants are typical for family-specific mutations, we also report the presence of alleles with significantly reduced activity among common population variants. We propose that some of these common variants act as modifiers and contribute to the ultimate phenotypic outcome in these patients; furthermore, we draw parallels with strain-specific modifiers in model organisms to bolster this interpretation. PMID:19553149

  20. Flowing with the changing needs of hydrogeology instruction

    Directory of Open Access Journals (Sweden)

    T. Gleeson

    2012-01-01

    Full Text Available Hydrogeology is now taught in a broad spectrum of departments and institutions to students with diverse backgrounds. Successful instruction in hydrogeology thus requires a variety of pedagogical approaches depending on desired learning outcomes and the diverse background of students. We review the pedagogical literature in hydrogeology to highlight recent advances and analyze a 2005 survey of 68 hydrogeology instructors. The literature and survey results suggest there are ~15 topics that are considered crucial by most hydrogeologists and >100 other topics that are considered crucial by some hydrogeologists. The crucial topics focus on properties of aquifers and fundamentals of groundwater flow, and should likely be part of all undergraduate hydrogeology courses. Other topics can supplement and support these crucial topics, depending on desired learning outcomes. Classroom settings continue to provide a venue for emphasizing fundamental knowledge. However, recent pedagogical advances are biased towards field and laboratory instruction with a goal of bolstering experiential learning. Field methods build on the fundamentals taught in the classroom and emphasize the collection of data, data uncertainty, and the development of vocational skills. Laboratory and computer-based exercises similarly build on theory, and offer an opportunity for data analysis and integration. The literature suggests curricula at all levels should ideally balance field, laboratory, and classroom pedagogy into an iterative and integrative whole. An integrated approach leads to greater student motivation and advancement of theoretical and vocational knowledge.

  1. Effectively Responding to Public Scrutiny When Communicating Climate Science.

    Science.gov (United States)

    Huertas, A.; Halpern, M.

    2014-12-01

    Climate researchers face regular scrutiny of their work from groups outside academia. In recent years, interest groups that oppose climate policy have targeted scientists with hate-mail campaigns, invasive document requests, hostile questioning and legal threats. In their day-to-day work, scientists struggle to respond to heated discussions about their research, whether from online commentators, opinion columnists, or special interest groups. Based on decades of experience and interviews with scientists, the Union of Concerned Scientists has developed a guide for communicating science amid heightened scrutiny. Building on the information contained in the UCS guide, this presentation will discuss best practices for climate researchers, including suggestions for when scrutiny can be ignored or when it deserves a response and methods for responding that can uphold scientific integrity while also protecting an individual researcher's reputation and ability to publicly communicate. Examples include scientists who have responded to bloggers criticizing their research, advocacy groups demanding their personal emails and policymakers targeting them with personal attacks. In understanding how to respond to scrutiny, scientists can bolster their own ability to communicate and curtail the chilling effect that scrutiny can have on other scientists conducting public enegagement.

  2. IAEA Director General addresses efforts to protect against nuclear terrorism before UN General Assembly

    International Nuclear Information System (INIS)

    The Director General of the IAEA, Dr. Mohamed ElBaradei, said October 22 in New York that the September 11 attacks on the United States had been a 'wake-up call' to everyone that more can and must be done to bolster security as an integral part of the management of national nuclear programmes. In support of that effort, he had already initiated a thorough review of all IAEA activities and programmes relevant to preventing acts of terrorism involving nuclear and other radioactive materials. 'The Agency is engaged in a variety of activities relevant to combating nuclear terrorism -- including programmes to ensure physical security, to help prevent and respond to illicit trafficking of nuclear material and other radioactive sources, to promote the safety of nuclear facilities, to safeguard nuclear material against non-peaceful uses, and to respond to emergencies', he said. Each of these programmes was being reviewed in-depth to identify additional measures that need to be taken in the light of recent events. In particular, expanding the scope and reach of many of the Agency's security and safety services was being considered. Also, existing conventions and guidelines, including the Convention on the Physical Protection of Nuclear Material, would be examined to ensure that they were comprehensive and effective, and efforts would be redoubled to ensure their universal application. The full text of the Director General's speech is available on the IAEA Web site www.iaea.org/worldatom/Press/Statements

  3. NASA Astronauts on Soyuz: Experience and Lessons for the Future

    Science.gov (United States)

    2010-01-01

    The U. S., Russia, and, China have each addressed the question of human-rating spacecraft. NASA's operational experience with human-rating primarily resides with Mercury, Gemini, Apollo, Space Shuttle, and International Space Station. NASA s latest developmental experience includes Constellation, X38, X33, and the Orbital Space Plane. If domestic commercial crew vehicles are used to transport astronauts to and from space, Soyuz is another example of methods that could be used to human-rate a spacecraft and to work with commercial spacecraft providers. For Soyuz, NASA's normal assurance practices were adapted. Building on NASA's Soyuz experience, this report contends all past, present, and future vehicles rely on a range of methods and techniques for human-rating assurance, the components of which include: requirements, conceptual development, prototype evaluations, configuration management, formal development reviews (safety, design, operations), component/system ground-testing, integrated flight tests, independent assessments, and launch readiness reviews. When constraints (cost, schedule, international) limit the depth/breadth of one or more preferred assurance means, ways are found to bolster the remaining areas. This report provides information exemplifying the above safety assurance model for consideration with commercial or foreign-government-designed spacecraft. Topics addressed include: U.S./Soviet-Russian government/agency agreements and engineering/safety assessments performed with lessons learned in historic U.S./Russian joint space ventures

  4. Grist to the Mill of Anti-evolutionism: The Failed Strategy of Ruling the Supernatural Out of Science by Philosophical Fiat

    Science.gov (United States)

    Boudry, Maarten; Blancke, Stefaan; Braeckman, Johan

    2012-08-01

    According to a widespread philosophical opinion, science is strictly limited to investigating natural causes and putting forth natural explanations. Lacking the tools to evaluate supernatural claims, science must remain studiously neutral on questions of metaphysics. This (self-imposed) stricture, which goes under the name of `methodological naturalism', allows science to be divorced from metaphysical naturalism or atheism, which many people tend to associate with it. However, ruling the supernatural out of science by fiat is not only philosophically untenable, it actually provides grist to the mill of anti-evolutionism. The philosophical flaws in this conception of methodological naturalism have been gratefully exploited by advocates of intelligent design creationism to bolster their false accusations of naturalistic bias and dogmatism on the part of modern science. We argue that it promotes a misleading view of the scientific endeavor and is at odds with the foremost arguments for evolution by natural selection. Reconciling science and religion on the basis of such methodological strictures is therefore misguided.

  5. On the evolutionary advantage of multi-cusped teeth.

    Science.gov (United States)

    Constantino, Paul J; Bush, Mark B; Barani, Amir; Lawn, Brian R

    2016-08-01

    A hallmark of mammalian evolution is a progressive complexity in postcanine tooth morphology. However, the driving force for this complexity remains unclear: whether to expand the versatility in diet source, or to bolster tooth structural integrity. In this study, we take a quantitative approach to this question by examining the roles of number, position and height of multiple cusps in determining sustainable bite forces. Our approach is to use an extended finite-element methodology with due provision for step-by-step growth of an embedded crack to determine how fracture progresses with increasing occlusal load. We argue that multi-cusp postcanine teeth are well configured to withstand high bite forces provided that multiple cusps are contacted simultaneously to share the load. However, contact on a single near-wall cusp diminishes the strength. Location of the load points and cusp height, rather than cusp number or radius, are principal governing factors. Given these findings, we conclude that while complex tooth structures can enhance durability, increases in cusp number are more likely to be driven by the demands of food manipulation. Structural integrity of complex teeth is maintained when individual cusps remain sufficiently distant from the side walls and do not become excessively tall relative to tooth width. PMID:27558851

  6. Environmental valuation for long-term strategic planning. The case of the Brazilian power sector

    International Nuclear Information System (INIS)

    If not properly dealt with over compatible horizons, environmental issues may cause ventures to incur higher costs and extend over longer implementation periods. Prompted by the uncertainties and risks inherent in these issues, as well as by the need for long-term plans to incorporate sustainable development principles, the Brazilian Power Sector is encouraging the inclusion of environmental aspects as a decision variable right from the start of the planning cycle. The purpose of this paper is to bolster efforts to include in this sector's expansion plans, costs resulting from environmental degradation of the environment. The paper offers an overview of the methodology developed to assess and include in long-term planning for this sector, external environmental costs linked to hydro-power and thermo-power generation. It suggests the use of environmental economic valuation techniques a practice commonly used to analyze the degradation of natural capital in various countries as well as assessing projects and programs, adopting the premises and simplifications required for application over the longer term.21 refs

  7. The Alliance Negotiation Scale: A psychometric investigation.

    Science.gov (United States)

    Doran, Jennifer M; Safran, Jeremy D; Muran, J Christopher

    2016-08-01

    This study investigates the utility and psychometric properties of a new measure of psychotherapy process, the Alliance Negotiation Scale (ANS; Doran, Safran, Waizmann, Bolger, & Muran, 2012). The ANS was designed to operationalize the theoretical construct of negotiation (Safran & Muran, 2000), and to extend our current understanding of the working alliance concept (Bordin, 1979). The ANS was also intended to improve upon existing measures such as the Working Alliance Inventory (WAI; Horvath & Greenberg, 1986, 1989) and its short form (WAI-S; Tracey & Kokotovic, 1989) by expanding the emphasis on negative therapy process. The present study investigates the psychometric validity of the ANS test scores and interpretation-including confirming its original factor structure and evaluating its internal consistency and construct validity. Construct validity was examined through the ANS' convergence and divergence with several existing scales that measure theoretically related constructs. The results bolster and extend previous findings about the psychometric integrity of the ANS, and begin to illuminate the relationship between negotiation and other important variables in psychotherapy research. (PsycINFO Database Record PMID:26460895

  8. Gender Differences in Cognitive and Noncognitive Factors Related to Achievement in Organic Chemistry

    Science.gov (United States)

    Turner, Ronna C.; Lindsay, Harriet A.

    2003-05-01

    For many college students in the sciences, organic chemistry poses a difficult challenge. Indeed, success in organic chemistry has proven pivotal in the careers of a vast number of students in a variety of science disciplines. A better understanding of the factors that contribute to achievement in this course should contribute to efforts to increase the number of students in the science disciplines. Further, an awareness of gender differences in factors associated with achievement should aid efforts to bolster the participation of women in chemistry and related disciplines. Using a correlation research design, the individual relationships between organic chemistry achievement and each of several cognitive variables and noncognitive variables were assessed. In addition, the relationships between organic chemistry achievement and combinations of these independent variables were explored. Finally, gender- and instructor-related differences in the relationships between organic chemistry achievement and the independent variables were investigated. Cognitive variables included the second-semester general chemistry grade, the ACT English, math, reading, and science-reasoning scores, and scores from a spatial visualization test. Noncognitive variables included anxiety, confidence, effectance motivation, and usefulness. The second-semester general chemistry grade was found to be the best indicator of performance in organic chemistry, while the effectiveness of other predictors varied between instructors. In addition, gender differences were found in the explanations of organic chemistry achievement variance provided by this study. In general, males exhibited stronger correlations between predictor variables and organic chemistry achievement than females.

  9. Open Education Resources: The New Paradigm in Academic Libraries

    Directory of Open Access Journals (Sweden)

    Carmen Mitchell

    2014-04-01

    Full Text Available Academic library budgets are contracting while library usage is increasing. How can academic libraries best help campuses reduce costs and better serve their communities? One strategy is collecting campus-created content online and making it available through the campus Institutional Repository. All faculty, including tenure track and adjuncts, at California State University San Marcos were invited to participate in a brief Web-based survey with both quantitative and qualitative questions. With an 18% response rate, the survey results indicate a strong interest in free or reduced cost educational materials, as well as a high level of concern about the cost of educational materials. Faculty responses indicate they are looking for alternatives to high priced curriculum materials, and are looking to the library for assistance. The crisis in scholarly communication and educational budgets is coming together to create a surge of support for free or low cost educational resources. Many campuses across the country have created programs to support open educational resources, with the main push coming from campus libraries or librarians. The data from this survey and examination of current campus climate, combined with the analysis of implementation factors by other organizations, will bolster the argument for libraries to create open repositories for campus scholarship.

  10. Development of a data mining and imaging informatics display tool for a multiple sclerosis e-folder system

    Science.gov (United States)

    Liu, Margaret; Loo, Jerry; Ma, Kevin; Liu, Brent

    2011-03-01

    Multiple sclerosis (MS) is a debilitating autoimmune disease of the central nervous system that damages axonal pathways through inflammation and demyelination. In order to address the need for a centralized application to manage and study MS patients, the MS e-Folder - a web-based, disease-specific electronic medical record system - was developed. The e-Folder has a PHP and MySQL based graphical user interface (GUI) that can serve as both a tool for clinician decision support and a data mining tool for researchers. This web-based GUI gives the e-Folder a user friendly interface that can be securely accessed through the internet and requires minimal software installation on the client side. The e-Folder GUI displays and queries patient medical records--including demographic data, social history, past medical history, and past MS history. In addition, DICOM format imaging data, and computer aided detection (CAD) results from a lesion load algorithm are also displayed. The GUI interface is dynamic and allows manipulation of the DICOM images, such as zoom, pan, and scrolling, and the ability to rotate 3D images. Given the complexity of clinical management and the need to bolster research in MS, the MS e-Folder system will improve patient care and provide MS researchers with a function-rich patient data hub.

  11. Racial science, geopolitics, and empires: paradoxes of power.

    Science.gov (United States)

    Tilley, Helen

    2014-12-01

    Scholars interested in the history of racial science continue to puzzle over the ways in which such ideas endure. This essay takes up a variant on this theme by considering how critiques of ideas about racial purity and hierarchies, expressed at the Universal Races Congress of 1911, were part of a larger intellectual project that simultaneously under- mined ideas of fixed racial types and bolstered identity categories defined in racial terms. Efforts to destabilize racial science in the early decades of the twentieth century often went hand in glove with burgeoning critiques of "white" and European domination in different parts of the world. This essay shines the spotlight on the paradoxical nature of these processes. While anthropologists helped to spearhead attempts to deconstruct mainstream pillars of racial science, they also left the door open for its reconstitution by refusing to reject classificatory schemes by group. And though global conversations about race and science tended to generate more cosmopolitan and egalitarian views, the very act of bringing together people from different places had the unintended effect of reinforcing racial identities and idioms, especially in the context of challenges to colonial rule. Finally, even as state building within empires ensured that racial taxonomies proliferated on the ground, imperial bureaucrats often avoided promoting racial science and research because such endeavors were a divisive force in transnational management. PMID:25665384

  12. Th Ages for Metal-Poor Stars

    CERN Document Server

    Johnson, J A; Johnson, Jennifer A.; Bolte, Michael

    2001-01-01

    With a sample of 22 metal-poor stars, we demonstrate that the heavy element abundance pattern (Z > 55) is the same as the r-process contributions to the solar nebula. This bolsters the results of previous studies that there is a universal r-process production pattern. We use the abundance of thorium in five metal-poor stars, along with an estimate of the initial Th abundance based on the abundances of stable r-process elements, to measure their ages. We have four field red giants with errors of 4.2 Gyr in their ages and one M92 giant with an error of 5.6 Gyr, based on considering the sources of observational error only. We obtain an average age of 11.4 Gyr, which depends critically on the assumption of an initial production ratio of Th/Eu of 0.496. If the Universe is 15 Gyr old, then the initial Th/Eu value should be 0.590, in agreement with some theoretical models of the r-process.

  13. Animal cryptochromes mediate magnetoreception by an unconventional photochemical mechanism.

    Science.gov (United States)

    Gegear, Robert J; Foley, Lauren E; Casselman, Amy; Reppert, Steven M

    2010-02-11

    Understanding the biophysical basis of animal magnetoreception has been one of the greatest challenges in sensory biology. Recently it was discovered that the light-dependent magnetic sense of Drosophila melanogaster is mediated by the ultraviolet (UV)-A/blue light photoreceptor cryptochrome (Cry). Here we show, using a transgenic approach, that the photoreceptive, Drosophila-like type 1 Cry and the transcriptionally repressive, vertebrate-like type 2 Cry of the monarch butterfly (Danaus plexippus) can both function in the magnetoreception system of Drosophila and require UV-A/blue light (wavelength below 420 nm) to do so. The lack of magnetic responses for both Cry types at wavelengths above 420 nm does not fit the widely held view that tryptophan triad-generated radical pairs mediate the ability of Cry to sense a magnetic field. We bolster this assessment by using a mutant form of Drosophila and monarch type 1 Cry and confirm that the tryptophan triad pathway is not crucial in magnetic transduction. Together, these results suggest that animal Crys mediate light-dependent magnetoreception through an unconventional photochemical mechanism. This work emphasizes the utility of Drosophila transgenesis for elucidating the precise mechanisms of Cry-mediated magnetosensitivity in insects and also in vertebrates such as migrating birds. PMID:20098414

  14. Erich Regener and the maximum in ionisation of the atmosphere

    CERN Document Server

    Carlson, P

    2014-01-01

    In the 1930s the German physicist Erich Regener (1881-1955) did important work on the measurement of the rate of production of ionisation deep under-water and in the atmosphere. He discovered, along with one of his students, Georg Pfotzer, the altitude at which the production of ionisation in the atmosphere reaches a maximum, often, but misleadingly, called the Pfotzer maximum. Regener was one of the first to estimate the energy density of cosmic rays, an estimate that was used by Baade and Zwicky to bolster their postulate that supernovae might be their source. Yet Regener's name is less recognised by present-day cosmic ray physicists than it should be largely because in 1937 he was forced to take early retirement by the National Socialists as his wife had Jewish ancestors. In this paper we briefly review his work on cosmic rays and recommend an alternative naming of the ionisation maximum. The influence that Regener had on the field through his son, his son-in-law, his grandsons and his students and through...

  15. ASTEROSEISMOLOGY OF THE SOLAR ANALOGS 16 Cyg A AND B FROM KEPLER OBSERVATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Metcalfe, T. S.; Dogan, G. [High Altitude Observatory, NCAR, P.O. Box 3000, Boulder, CO 80307 (United States); Chaplin, W. J.; Garcia, R. A.; Basu, S.; Deheuvels, S.; Miglio, A. [Kavli Institute for Theoretical Physics, Kohn Hall, University of California, Santa Barbara, CA 93106 (United States); Appourchaux, T. [Institut d' Astrophysique Spatiale, Univ Paris-Sud, UMR8617, CNRS, Batiment 121, 91405 Orsay Cedex (France); Brandao, I. [Centro de Astrofisica and Faculdade de Ciencias, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Creevey, O. L.; Salabert, D. [Laboratoire Lagrange, UMR7293, Observatoire de la Cote d' Azur, Universite de Nice Sophia-Antipolis, CNRS, BP 4229, 06304 Nice Cedex 4 (France); Eggenberger, P. [Observatoire de Geneve, Universite de Geneve, 51 Ch. des Maillettes, CH-1290 Sauverny (Switzerland); Karoff, C. [Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Stello, D.; Benomar, O. [Sydney Institute for Astronomy (SIfA), School of Physics, University of Sydney, NSW 2006 (Australia); Y Latin-Small-Letter-Dotless-I ld Latin-Small-Letter-Dotless-I z, M.; Celik, Z. [Department of Astronomy and Space Sciences, Ege University, Bornova, 35100 Izmir (Turkey); Antia, H. M. [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400005 (India); Howe, R. [School of Physics and Astronomy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom); Regulo, C. [Instituto de Astrofisica de Canarias, 38205 La Laguna, Tenerife (Spain); and others

    2012-03-20

    The evolved solar-type stars 16 Cyg A and B have long been studied as solar analogs, yielding a glimpse into the future of our own Sun. The orbital period of the binary system is too long to provide meaningful dynamical constraints on the stellar properties, but asteroseismology can help because the stars are among the brightest in the Kepler field. We present an analysis of three months of nearly uninterrupted photometry of 16 Cyg A and B from the Kepler space telescope. We extract a total of 46 and 41 oscillation frequencies for the two components, respectively, including a clear detection of octupole (l = 3) modes in both stars. We derive the properties of each star independently using the Asteroseismic Modeling Portal, fitting the individual oscillation frequencies and other observational constraints simultaneously. We evaluate the systematic uncertainties from an ensemble of results generated by a variety of stellar evolution codes and fitting methods. The optimal models derived by fitting each component individually yield a common age (t = 6.8 {+-} 0.4 Gyr) and initial composition (Z{sub i} = 0.024 {+-} 0.002, Y{sub i} = 0.25 {+-} 0.01) within the uncertainties, as expected for the components of a binary system, bolstering our confidence in the reliability of asteroseismic techniques. The longer data sets that will ultimately become available will allow future studies of differential rotation, convection zone depths, and long-term changes due to stellar activity cycles.

  16. Post-Conflict History Education in Finland, South Africa and Bosnia-Herzegovina

    Directory of Open Access Journals (Sweden)

    Sirkka Ahonen

    2013-08-01

    Full Text Available A post-conflict society tends to get locked in a history war. As the practice of history in its broad sense is a moral craft, representations of guilt and victimhood prevail in social memory. The representations are often bolstered by mythical references, wherefore deconstruction of myths is expected from history education for the purposes of post-conflict reconciliation. This article deals with the post-conflict uses of history in Finland, South Africa and Bosnia-Herzegovina. The three cases constitute examples of a class war, a race conflict and an ethno-religious armed clash. The memory politics and history curricula differ between the cases. Their comparison indicates, how far an imposition of one ´truth´, a dialogue of two ´truths´ and segregation of different memory communities are feasible strategies of post-conflict history education. The article suggests that history lessons can be an asset instead of a liability in the pursuit of reconciliation.

  17. Lab-Based Nanofocus X-ray CT as a Supplemental Analysis Tool in Studies of Earth Materials

    Science.gov (United States)

    Santillan, J. D.; Maher, K.; O'Henley, G.; Zacher, G.; Brunke, O.

    2009-12-01

    In recent years, lab-based X-ray CT has become a viable alternative to the use of a synchrotron beamline for Earth Science researchers. CT for geological research purposes can lead to a new dimension of understanding of the distribution of rock properties. Because it has only been a few years since lab-based nano-CT has been applied to such problems, the breadth of these studies in quickly expanding. Results of studies we have performed show data consistent with those obtained using synchrotron radiation. Our presentation will focus on studies where CT is not the primary investigative technique, but where the information gained can strongly inform the approach taken using other methods, such as XRD. Using CT to bolster other techniques will be of great interest as X-ray CT is applied to solving a greater variety of geological problems. We have examined several samples using X-ray CT in sizes up to 120 mm in diameter and weighing up to 1 kg with voxel-resolutions down to CT. X-ray CT (positive image)

  18. Driving Green: Toward the Prediction and Influence of Efficient Driving Behavior

    Science.gov (United States)

    Newsome, William D.

    Sub-optimal efficiency in activities involving the consumption of fossil fuels, such as driving, contribute to a miscellany of negative environmental, political, economic and social externalities. Demonstrations of the effectiveness of feedback interventions can be found in countless organizational settings, as can demonstrations of individual differences in sensitivity to feedback interventions. Mechanisms providing feedback to drivers about fuel economy are becoming standard equipment in most new vehicles, but vary considerably in their constitution. A keystone of Radical Behaviorism is the acknowledgement that verbal behavior appears to play a role in mediating apparent susceptibility to influence by contingencies of varying delay. In the current study, samples of verbal behavior (rules) were collected in the context of a feedback intervention to improve driving efficiency. In an analysis of differences in individual responsiveness to the feedback intervention, the rate of novel rules per week generated by drivers is revealed to account for a substantial proportion of the variability in relative efficiency gains across participants. The predictive utility of conceptual tools, such as the basic distinction among contingency-shaped and rule governed behavior, the elaboration of direct-acting and indirect-acting contingencies, and the psychological flexibility model, is bolstered by these findings.

  19. Weed flora of South Africa 2: power shifts in the veld

    Directory of Open Access Journals (Sweden)

    M. J. Wells

    1983-12-01

    Full Text Available This paper, the second in a series analysing data from the National Weed List, concentrates on weedy changes that affect the indigenous flora. The incidence of weediness and of threatened species is used as an indication of success or failure of families under prevailing conditions of disturbance. The resulting power shifts between indigenous families and the impact of exotic weeds on the situation are reviewed. Many power shifts are taking place between indigenous species in the veld. Superficially it seems as though a relatively few invasive species are displacing a larger number of threatened species, but evidence from Natal points to more species increasing than decreasing under conditions of over-utilization. Amongst small families power shifts are almost as prevalent and important as at species level. Seventeen small families have over 20% indigenous weed species. Thirty small families have over 20% threatened species, and 21 small families have had their species numbers bolstered by more than  20% by exotic weeds. A very few large and medium-sized families contain over 50% of our weeds and our threatened species. It is mostly temperate (Cape families that are under pressure relative to more tropical families. This trend is echoed at sub-family level within the Fabaceae.

  20. Gravitational anomalies and one-dimensional behavior of black holes

    International Nuclear Information System (INIS)

    It has been pointed out by Bekenstein and Mayo that the behavior of the black hole’s entropy or information flow is similar to information flow through one-dimensional channel. Here I analyze the same issue with the use of gravitational anomalies. The rate of the entropy change (S.) and the power (P) of the Hawking emission are calculated from the relevant components of the anomalous stress tensor under the Unruh vacuum condition. I show that the dependence of S. on the power is S. ∝P1/2, which is identical to that for the information flow in a one-dimensional system. This is established by using the (1+1)-dimensional gravitational anomalies first. Then the fact is further bolstered by considering the (1+3)-dimensional gravitational anomalies. It is found that, in the former case, the proportionality constant is exactly identical to the one-dimensional situation, known as Pendry’s formula, while in the latter situation its value decreases