WorldWideScience

Sample records for bohrium 275

  1. 21 CFR 556.275 - Fenbendazole.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Fenbendazole. 556.275 Section 556.275 Food and... Residues of New Animal Drugs § 556.275 Fenbendazole. (a) Acceptable daily intake (ADI). The ADI for total residues of fenbendazole is 40 micrograms per kilogram of body weight per day. (b) Tolerances—(1)...

  2. 47 CFR 27.5 - Frequencies.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Frequencies. 27.5 Section 27.5... COMMUNICATIONS SERVICES General Information § 27.5 Frequencies. (a) 2305-2320 MHz and 2345-2360 MHz bands. The following frequencies are available for WCS in the 2305-2320 MHz and 2345-2360 MHz bands: (1) Two...

  3. 7 CFR 275.11 - Sampling.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Sampling. 275.11 Section 275.11 Agriculture... § 275.11 Sampling. (a) Sampling plan. Each State agency shall develop a quality control sampling plan which demonstrates the integrity of its sampling procedures. (1) Content. The sampling plan...

  4. 28 CFR 27.5 - Review.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Review. 27.5 Section 27.5 Judicial... Investigating Reprisal Allegations and Ordering Corrective Action § 27.5 Review. The Complainant or the FBI may..., review by the Deputy Attorney General of that determination or order. The Deputy Attorney General...

  5. 275 C Downhole Microcomputer System

    Energy Technology Data Exchange (ETDEWEB)

    Chris Hutchens; Hooi Miin Soo

    2008-08-31

    An HC11 controller IC and along with serial SRAM and ROM support ICs chip set were developed to support a data acquisition and control for extreme temperature/harsh environment conditions greater than 275 C. The 68HC11 microprocessor is widely used in well logging tools for control, data acquisition, and signal processing applications and was the logical choice for a downhole controller. This extreme temperature version of the 68HC11 enables new high temperature designs and additionally allows 68HC11-based well logging tools and MWD tools to be upgraded for high temperature operation in deep gas reservoirs, The microcomputer chip consists of the microprocessor ALU, a small boot ROM, 4 kbyte data RAM, counter/timer unit, serial peripheral interface (SPI), asynchronous serial interface (SCI), and the A, B, C, and D parallel ports. The chip is code compatible with the single chip mode commercial 68HC11 except for the absence of the analog to digital converter system. To avoid mask programmed internal ROM, a boot program is used to load the microcomputer program from an external mask SPI ROM. A SPI RAM IC completes the chip set and allows data RAM to be added in 4 kbyte increments. The HC11 controller IC chip set is implemented in the Peregrine Semiconductor 0.5 micron Silicon-on-Sapphire (SOS) process using a custom high temperature cell library developed at Oklahoma State University. Yield data is presented for all, the HC11, SPI-RAM and ROM. The lessons learned in this project were extended to the successful development of two high temperature versions of the LEON3 and a companion 8 Kbyte SRAM, a 200 C version for the Navy and a 275 C version for the gas industry.

  6. 32 CFR 275.5 - Responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 275.5 Section 275.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS... Responsibilities. (a) The Director of Administration and Management, Office of the Secretary of Defense shall:...

  7. 28 CFR 2.75 - Reconsideration proceedings.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Reconsideration proceedings. 2.75 Section 2.75 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF....75 Reconsideration proceedings. (a)(1) Following an initial or subsequent hearing, the Commission...

  8. Dicty_cDB: SLB275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLB275 (Link to dictyBase) - - - Contig-U16513-1 SLB275Z (Link... to Original site) - - SLB275Z 589 - - - - Show SLB275 Library SL (Link to library) Clone ID SLB275 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLB2-D/SLB275Q.Seq.d/ Representative seq. ID SLB27...5Z (Link to Original site) Representative DNA sequence >SLB275 (SLB275Q) /CSM/SL/SLB2-D/SLB275Q.Seq.d/ XXXXX...ignificant alignments: (bits) Value SLB275 (SLB275Q) /CSM/SL/SLB2-D/SLB275Q.Seq.d/ 1126 0.0 VFN233 (VFN233Q)

  9. Dicty_cDB: VHF275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHF275 (Link to dictyBase) - - - Contig-U15033-1 - (Link to Original site) VHF...275F 582 - - - - - - Show VHF275 Library VH (Link to library) Clone ID VHF275 (Link to dicty...iol.tsukuba.ac.jp/CSM/VH/VHF2-D/VHF275Q.Seq.d/ Representative seq. ID - (Link to ...Original site) Representative DNA sequence >VHF275 (VHF275Q) /CSM/VH/VHF2-D/VHF275Q.Seq.d/ ATAGTTACAAATAAATA...yyiyfhyllf*ypkt*livkiii*qngiy*hhfqvhqekmlmy*ivmveli iyq*viiqhilvn*lmeqeldgiiiqqmlmvwli*ifqim*igi**iigqdqvahilvvg efqhf

  10. Properties of an $\\alpha$ particle in a Bohrium $270$ Nucleus under the Generalized Symmetric Woods-Saxon Potential

    CERN Document Server

    Lütfüoğlu, B C

    2016-01-01

    The energy eigenvalues and the wave functions of an $\\alpha$ particle in a Bohrium $270$ nucleus were calculated by solving Schr\\"odinger equation for Generalized Symmetric Woods-Saxon potential. Using the energy spectrum by excluding and including the quasi-bound eigenvalues, entropy, internal energy, Helmholtz energy, and specific heat, as functions of reduced temperature were calculated. Stability and emission characteristics are interpreted in terms of the wave and thermodynamic functions. The kinetic energy of a decayed $\\alpha$ particle was calculated using the quasi-bound states, which is found close to the experimental value.

  11. 32 CFR 275.3 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... OBTAINING INFORMATION FROM FINANCIAL INSTITUTIONS: RIGHT TO FINANCIAL PRIVACY ACT OF 1978 § 275.3...) A licensed sender of money or any other person who engages as a business in the transmission of... network of people who engage as a business in facilitating the transfer of money domestically...

  12. Reference: 275 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 275 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16176934i Chelysheva Liudm...|Bhatt Anuj M|Chelysheva Liudmila|Diallo Stéphanie|Gendrot Ghislaine|Grelon Mathilde|Horlow Christine|Mercie

  13. 21 CFR 173.275 - Hydrogenated sperm oil.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Hydrogenated sperm oil. 173.275 Section 173.275... CONSUMPTION Solvents, Lubricants, Release Agents and Related Substances § 173.275 Hydrogenated sperm oil. The food additive hydrogenated sperm oil may be safely used in accordance with the following...

  14. 7 CFR 275.21 - Quality control review reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  15. 38 CFR 3.275 - Criteria for evaluating net worth.

    Science.gov (United States)

    2010-07-01

    ... net worth. 3.275 Section 3.275 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Improved Pension Program Which Became Effective January 1, 1979 § 3.275 Criteria for evaluating net worth. (a) General. The following rules are for application in determining the corpus of estate or net...

  16. 7 CFR 275.13 - Review of negative cases.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Review of negative cases. 275.13 Section 275.13... § 275.13 Review of negative cases. (a) General. A sample of households whose applications for food stamp... month or effective for the sample month shall be selected for quality control review. These...

  17. 21 CFR 73.275 - Dried algae meal.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Dried algae meal. 73.275 Section 73.275 Food and... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.275 Dried algae meal. (a) Identity. The color additive dried algae meal is a dried mixture of algae cells (genus Spongiococcum, separated from its culture...

  18. 48 CFR 236.275 - Construction of industrial resources.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Construction of industrial resources. 236.275 Section 236.275 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... CONTRACTS Special Aspects of Contracting for Construction 236.275 Construction of industrial resources....

  19. 7 CFR 275.16 - Corrective action planning.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Corrective action planning. 275.16 Section 275.16... Corrective action planning. (a) Corrective action planning is the process by which State agencies shall...)/management unit(s) in the planning, development, and implementation of corrective action are those which:...

  20. 49 CFR 234.275 - Processor-based systems.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION GRADE CROSSING SIGNAL SYSTEM SAFETY AND STATE ACTION PLANS Maintenance, Inspection, and Testing Requirements for Processor-Based Systems § 234.275 Processor-based systems. (a... 49 Transportation 4 2010-10-01 2010-10-01 false Processor-based systems. 234.275 Section...

  1. 27 CFR 24.275 - Prepayment of tax.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Prepayment of tax. 24.275 Section 24.275 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... of tax. (a) General. The proprietor shall, before removal of wine for consumption or sale,...

  2. 40 CFR 421.275 - Pretreatment standards for existing sources.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Pretreatment standards for existing sources. 421.275 Section 421.275 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Rare...

  3. 49 CFR 192.275 - Cast iron pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Cast iron pipe. 192.275 Section 192.275... Cast iron pipe. (a) Each caulked bell and spigot joint in cast iron pipe must be sealed with mechanical leak clamps. (b) Each mechanical joint in cast iron pipe must have a gasket made of a...

  4. 17 CFR 275.206(4)-8 - Pooled investment vehicles.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Pooled investment vehicles... COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT ADVISERS ACT OF 1940 § 275.206(4)-8 Pooled investment vehicles. (a) Prohibition. It shall constitute a fraudulent, deceptive, or manipulative...

  5. 7 CFR 1822.275 - Actions after sites are developed.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE LOANS AND GRANTS PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing... 1822.275 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE... in accordance with 7 CFR part 3550, subpart D or otherwise in accordance with prior approval of...

  6. 24 CFR 990.275 - Project-based management (PBM).

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Project-based management (PBM). 990... URBAN DEVELOPMENT THE PUBLIC HOUSING OPERATING FUND PROGRAM Asset Management § 990.275 Project-based... of rental housing at the project level. Under PBM, these property management services are...

  7. Composite augmentation phalloplasty: personal experience after 275 patients

    OpenAIRE

    Juan Monreal

    2015-01-01

    Aim: To report the author's experience in augmentation phalloplasty by studying a retrospective series of patients who underwent fat grafting for girth enhancement or a composite technique based on suspensory ligament release plus fat grafting performed simultaneously. Methods: The author analyzed retrospectively the outcomes of 275 augmentation phalloplasty procedures performed in 259 patients until November 2013. Of these, 127 correspond to girth augmentation with fat grafting and 148 to co...

  8. 32 CFR Appendix A to Part 275 - Obtaining Basic Identifying Account Information

    Science.gov (United States)

    2010-07-01

    ... A Appendix A to Part 275 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY... FINANCIAL PRIVACY ACT OF 1978 Pt. 275, App. A Appendix A to Part 275—Obtaining Basic Identifying Account Information A. A DoD law enforcement office may issue a formal written request for basic identifying...

  9. 275 C Downhole Switched-Mode Power Supply

    Energy Technology Data Exchange (ETDEWEB)

    Chris Hutchens; Vijay Madhuravasal

    2008-08-31

    A vee-square (V2) control based controller IC is developed for a switch mode power supply capable of operating at extreme temperature/harsh environment conditions. A buck type regulator with silicon carbide power junction field effect transistors (JFET) as power devices is used to analyze the performance of controller. Special emphases are made on the analog sub-blocks--voltage reference, operational transconductance amplifier and comparator as individual building blocks. Transformer coupled gate drives and high temperature operable magnetic cores and capacitors are identified and tested for use in the design. Conventional ceramic chip packaging of ICs combined with lead carrier type mounting of passive filter components is introduced for hybrid packaging of the complete product. The developed SMPS is anticipated to support the operation of down-hole microcontrollers and other electronics devices that require low/medium power filtered dc inputs over an operating temperature of 275 C.

  10. Composite augmentation phalloplasty: personal experience after 275 patients

    Directory of Open Access Journals (Sweden)

    Juan Monreal

    2015-03-01

    Full Text Available Aim: To report the author's experience in augmentation phalloplasty by studying a retrospective series of patients who underwent fat grafting for girth enhancement or a composite technique based on suspensory ligament release plus fat grafting performed simultaneously. Methods: The author analyzed retrospectively the outcomes of 275 augmentation phalloplasty procedures performed in 259 patients until November 2013. Of these, 127 correspond to girth augmentation with fat grafting and 148 to composite augmentation phalloplasty (girth augmentation with fat grafting and length improvement by suspensory ligament release. In 16 patients girth and length enhancement were performed in two separate procedures. Results: Of this 259 patients, 87 underwent postoperative follow-up for at least 12 months and 160 patients underwent follow-up for at least 6 months. The average increase in circumference at 6 months was 1.7 cm (1.57 cm at 12 months and the average increase in length of 3.2 cm (3.1 cm at 12 months. Twenty-two patients showed minor complications that were treated without sequelae and without influencing the final result. Conclusion: By judicious use of currently available techniques, it is possible to achieve stable increases in penis size. The use of composite techniques provides better final results than the use of individual techniques performed alone due to the increase of the actual volume of the penis. An adequate informed consent is essential in all patients due to the unrealistic expectations expressed by the majority of them.

  11. East Weddell Sea echinoids from the JR275 expedition

    Directory of Open Access Journals (Sweden)

    Thomas Saucède

    2015-05-01

    Full Text Available Information regarding the echinoids in this dataset is based on the Agassiz Trawl (AGT and epibenthic sledge (EBS samples collected during the British Antarctic Survey cruise JR275 on the RRS James Clark Ross in the austral summer 2012. A total of 56 (1 at the South Orkneys and 55 in the Eastern Weddell Sea Agassiz Trawl and 18 (2 at the South Orkneys and 16 in the Eastern Weddell Sea epibenthic sledge deployments were performed at depths ranging from ~280 to ~2060 m. This presents a unique collection for the Antarctic benthic biodiversity assessment of an important group of benthic invertebrates. In total 487 specimens belonging to six families, 15 genera, and 22 morphospecies were collected. The species richness per station varied between one and six. Total species richness represents 27% of the 82 echinoid species ever recorded in the Southern Ocean (David et al. 2005b, Pierrat et al. 2012, Saucède et al. 2014. The Cidaridae (sub-family Ctenocidarinae and Schizasteridae are the two most speciose families in the dataset. They comprise seven and nine species respectively. This is illustrative of the overall pattern of echinoid diversity in the Southern Ocean where 65% of Antarctic species belong to the families Schizasteridae and Cidaridae (Pierrat et al. 2012.

  12. 24 CFR 213.275 - Nature of the Cooperative Management Housing Insurance Fund.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Nature of the Cooperative Management Housing Insurance Fund. 213.275 Section 213.275 Housing and Urban Development Regulations Relating... Nature of the Cooperative Management Housing Insurance Fund. The Cooperative Management Housing...

  13. 17 CFR 275.204A-1 - Investment adviser codes of ethics.

    Science.gov (United States)

    2010-04-01

    ... enforce a written code of ethics that, at a minimum, includes: (1) A standard (or standards) of business... ethics. 275.204A-1 Section 275.204A-1 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... codes of ethics. (a) Adoption of code of ethics. If you are an investment adviser registered or...

  14. 32 CFR Appendix C to Part 275 - Obtaining Access by Administrative or Judicial Subpoena or by Formal Written Request

    Science.gov (United States)

    2010-07-01

    ... Subpoena or by Formal Written Request C Appendix C to Part 275 National Defense Department of Defense... INSTITUTIONS: RIGHT TO FINANCIAL PRIVACY ACT OF 1978 Pt. 275, App. C Appendix C to Part 275—Obtaining Access by... Appendix K to this part and shall: 1. State that the request is issued under 12 U.S.C. Chapter 35 and...

  15. Clinical analysis of 275 cases of acute drug-induced liver disease

    Institute of Scientific and Technical Information of China (English)

    LI Lei; JIANG Wei; WANG Jiyao

    2007-01-01

    In order to analyze the causative drugs,clinical manifestation and pathological characteristics of the patients with acute drug-induced liver disease,from January 2000 to December 2005,275 cases diagnosed as acute druginduced liver diseases according to Maria Criterion and hospitalized in Zhongshan Hospital of Fudan University were retrospectively reviewed.Each was determined by drug history,clinical symptoms and signs,laboratory tests and therapeutic effects.In 41 cases,the diagnosis was confirmed by liver biopsy.The proportion of acute drug-induced liver disease among all of the acute liver injuries was annually increased.The most common drugs which induced acute liver injuries were traditional Chinese herb medicine (23.3 %,64/275 cases),antineoplastics (15.3%,42/275),hormones and other immunosuppressant agents (13.8%,38/275),antihypertensive drugs and other cardiovascular drugs (10.2 %,28/275),NSAIDs (8.7%,24/275) respectively.Hepatocellular injury was the predominant type in these cases (132 cases,48%).The principal clinical manifestation included nausea (54.8%),fatigue (50.2%),jaundice (35.6%).27.9% patients were asymptomatic.Most patients were cured with good prognosis.The total effective rate was 94.2% after treatment.The clinicians should pay attention to the prevention,diagnosis and therapy of drug-induced liver disease.

  16. Progress of 275 kV-3 kA YBCO HTS cable

    Science.gov (United States)

    Yagi, M.; Mukoyama, S.; Amemiya, N.; Ishiyama, A.; Wang, X.; Aoki, Y.; Saito, T.; Ohkuma, T.; Maruyama, O.

    2011-11-01

    A 275 kV-3 kA high temperature superconducting (HTS) cable has been developed in the Materials & Power Applications of Coated Conductors (M-PACC) project. AC loss reduction of a two-layer HTS conductor was undertaken by removing the edges of YBCO tapes with low critical current density. The HTS conductor using these tapes was fabricated, and low loss of 0.235 W/m at 3 kA rms was achieved. The 275 kV-3 kA cable was designed, and the 2 m model cables were fabricated. This cable had 325 mm 2 copper stranded former inside the HTS conductor and a 310 mm 2 copper shield layer on the HTS shield layer for over-current protection. These cables withstood an over-current of 63.0 kA for 0.6 s, which is the worst situation for 275 kV systems. The partial discharge (PD) and V- t characteristics of a liquid nitrogen (LN 2)/polypropylene (PP) laminated paper composite insulation system have been integrated into the design of the insulation for the 275 kV cable. The results revealed that the PD inception stress (PDIE) did not depend on the insulation thickness, and that lifetime indices of V- t characteristics at PD inception were as high as about 80-100.

  17. 17 CFR 275.206(4)-1 - Advertisements by investment advisers.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Advertisements by investment... COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT ADVISERS ACT OF 1940 § 275.206(4)-1 Advertisements.... 80b-3), directly or indirectly, to publish, circulate, or distribute any advertisement: (1)...

  18. 275例唐氏综合征患儿染色体分析%The chromosome karyotype of 275 examples of Down's syndrome

    Institute of Scientific and Technical Information of China (English)

    安会波; 刘征燕; 张丽丽

    2012-01-01

    Objective; Check the chromosome in peripheral blood of Down's syndrome suspected by clinic, who visited our hospital from 2. 2007 -3.2010. Methods; Cultivate lymphocyte in peripheral blood in nutritive medium, analyze the karyotype using G band. Results; Detected 275 examples of Down's syndrome, including 247 examples of simple type, 21 examples of translocation type and 7 examples of mosaicism type.%目的 对2007年2月至2010年3月期间来我院就诊,临床疑为先天愚型的患者进行外周血染色体检查.方法 用培养基培养外周血淋巴细胞,G显带进行染色体核型分析.结果 检出唐氏综合征患者275例,其中单纯型247例,易位型21例,嵌合型7例.

  19. 33 CFR 207.275 - McClellan-Kerr Arkansas River navigation system: use, administration, and navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false McClellan-Kerr Arkansas River navigation system: use, administration, and navigation. 207.275 Section 207.275 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS §...

  20. The class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells

    Directory of Open Access Journals (Sweden)

    Gianluigi Franci

    2013-08-01

    Exploitation of embryonic stem cells (ESC for therapeutic use and biomedical applications is severely hampered by the risk of teratocarcinoma formation. Here, we performed a screen of selected epi-modulating compounds and demonstrate that a transient exposure of mouse ESC to MS-275 (Entinostat, a class I histone deacetylase inhibitor (HDAC, modulates differentiation and prevents teratocarcinoma formation. Morphological and molecular data indicate that MS-275-primed ESCs are committed towards neural differentiation, which is supported by transcriptome analyses. Interestingly, in vitro withdrawal of MS-275 reverses the primed cells to the pluripotent state. In vivo, MS275-primed ES cells injected into recipient mice give only rise to benign teratomas but not teratocarcinomas with prevalence of neural-derived structures. In agreement, MS-275-primed ESC are unable to colonize blastocysts. These findings provide evidence that a transient alteration of acetylation alters the ESC fate.

  1. Discovery of Multi-target Anticancer Agents Based on HDAC Inhibitor MS-275 and 5-FU.

    Science.gov (United States)

    Jiang, Yuqi; Li, Xiaoguang; Li, Xiaoyang; Hou, Jinning; Ding, Yongzheng; Zhang, Jian; Xu, Wenfang; Zhang, Yingjie

    2016-01-01

    Histone deacetylases (HDACs) inhibitors have multiple effects targeting the cancer cells and have become one of the promising cancer therapeutics with possibly broad applicability. Combination of HDAC inhibitors with the cytotoxic fluorouracil (5-FU) showed additive and synergistic effects both in vitro and in vivo. To explore the possibility in cancer therapy of a bivalent agent that combines two bioactive groups within a single molecular architecture, we designed and synthesized new dual-acting compounds by combining the bioactive fragment of MS-275, a clinical HDACs inhibitor, with cytotoxic agent 5-FU. The target compounds 9a and 9b showed comparable HDACs inhibition with MS-275 and moderate antiproliferative acitivities against six cancer cells lines.

  2. Formation and early hydration characteristics of C2.75B1.25A3$ in binary system of C2.75B1.25A3$-C2S

    Directory of Open Access Journals (Sweden)

    Wang, Shoude

    2016-09-01

    Full Text Available C2.75B1.25A3$ (2.75CaO•1.25BaO• 3Al2O3• SO3 is one of the important minerals and it govern-directly the early-strength of belite-barium calcium sulphoaluminate cement. In this paper a binary system C2.75B1.25A3$-C2S is selected to investigate the formation of C2.75B1.25A3$. In the range of 1100 °C–1200 °C, the earlier formed C2S hinders the formation of C2.75B1.25A3$. On the contrary, when the temperature is in the range of 1200 °C–1350 °C, the initially formed C2S could provide a surface for the nucleation of C2.75B1.25A3$ and cut down the potential barrier (?Gk* for the heterogeneous nucleation of C2.75B1.25A3$, which contributes to its formation. Moreover, at 1350 °C, the large amount of previously formed C2S benefits the extent of formation of C2.75B1.25A3$. The possible reason was that it could prevent sulfur evaporation. In early hydration age, AFm and AFt originating from C2.75B1.25A3$ hydration are found within 2 h and 12 h under 95% RH at 1 °C, respectively, whereas C2S is unhydrated at this moment.En el cemento de sulfoaluminato de calcio y bario, el C2.75B1.25A3$ (2.75CaO•1.25BaO• 3Al2 O3• SO3 es una de las principales fases, y regula directamente la resistencia inicial del cemento. En este trabajo, se ha seleccionado el sistema binario C2.75B1.25A3$-C2S para investigar la formación de C2.75B1.25A3$. En el rango de 1100 °C-1200 °C, el C2S formado anteriormente impide la formación de C2.75B1.25A3$, mientras que cuando la temperatura está entre 1200 °C-1350 °C, el C2S proporcionaría una superficie de nucleación de C2.75B1.25A3$ reduciendo la barrera de potencial (?Gk* para la nucleación heterogénea de C2.75B1.25A3$, lo que contribuye a su formación. Además, a 1350 °C, la gran cantidad de C2S formado beneficia la formación de C2.75B1.25A3$, ya que podía prevenir la evaporación del azufre. En las primeras etapas de la hidratación (entre 2 y 12h y 95% HR a 1 ºC se pueden encontrar AFM y AFt

  3. GLFW 2.7.5发布,OpenGL应用框架

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    GLFW 2.7.5发布了,该版本修复了特定MacOSX版本下的编译错误,支持Cocoa的单调时间输入。 GLFW是一个OpenGL的应用框架,支持Linux和Windows。GLFW主要用来处理特定操作系统下的特定任务,例如OpenGL窗口管理、

  4. Development of Y-branch Joint for 275kV XLPE and Fluid Filled Cable

    Science.gov (United States)

    Goto, Takeshi; Yamashita, Makoto; Sakamaki, Masatoshi

    When a new UHV substation is built in an urban region, generally, an existing underground transmission line shall be diverted and drawn into the new substation. Compared with above mentioned construction method, enormous cost reduction of switching facilities and cable construction is expected with applying a Y-Branch Joint (YJ) which is able to be a 3-way joint. The YJ has already been applied for 154kV class circuit, however, it has not been investigated for 275kV class circuit. Since both XLPE and Fluid-Filled cable are presently used in 275kV class underground cable line, an universal design YJ for both cables have been investigated. The YJ was applied a compact design which was based on our sophisticated electrical stress control technology for 500kV prefabricated type joint. Furthermore, the design was based on its prefabricated assembling technology. The YJ was verified its electrical and mechanical performance as 275kV cable joint by completion of its assembling test and a long term electrical test.

  5. 32 CFR Appendix M to Part 275 - Format for Certificate of Compliance With the Right to Financial Privacy Act of 1978

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Format for Certificate of Compliance With the Right to Financial Privacy Act of 1978 M Appendix M to Part 275 National Defense Department of Defense... INSTITUTIONS: RIGHT TO FINANCIAL PRIVACY ACT OF 1978 Pt. 275, App. M Appendix M to Part 275—Format...

  6. 49 CFR 40.275 - What is the effect of procedural problems that are not sufficient to cancel an alcohol test?

    Science.gov (United States)

    2010-10-01

    ... in Alcohol Testing § 40.275 What is the effect of procedural problems that are not sufficient to... 49 Transportation 1 2010-10-01 2010-10-01 false What is the effect of procedural problems that are not sufficient to cancel an alcohol test? 40.275 Section 40.275 Transportation Office of the...

  7. Clinical characteristics of 275 pediatric cases of acquired immune deficiency syndrome%儿童艾滋病275例临床特点分析

    Institute of Scientific and Technical Information of China (English)

    赵燕; 庞琳; 云鹰; 刘中夫; 张福杰; 豆智慧; 程跃武; 唐志荣; 刘爱文; 彭国平; 乔晓春; 赵红心

    2008-01-01

    Objective To study the clinical characteristic of acquired immune deficiency syndrome (AIDS) patients younger than 15 years old and to explore the influence of human immunodeficiency virus (HIV) infection on them. Methods The clinical information, including demographic profile, clinical stages of the disease, laboratory test results and developmental status were gathered from 275 antiretroviral therapy naive patients. Results Seventy eight point nine percent patients were infected by vertical transmission. Sixteen percent were infected by receiving blood products. The average age was (7.6±3. 7) years, with 5 cases younger than 1 year old, 104 cases ranging from 1 - 5 years and 166 cases elder than 6 years. Seventy point one percent patients were classified as stage 3 or 4 according to World Health Organization definitions. The average CD4 count was ( 137 ± 159 )/μL, ( 304 ± 317 ) /μL and ( 1 246 ± 776 )/μL respectively in children elder than 6 years, ranging from 1 to 5 years and younger than 1 year. One hundred and eighty one cases suffered from anemia on different severity grading. The most common HIV related symdromes included persistent fever, skin damage, persistent diarrhea, oral candidiasis and recurrent upper respiratory tract infection. Among these infected children, 49. 6% showed height lower than x - 2s and 19. 9% showed weight lower than x - 2s. Conclusions Most survival pediatric AIDS patients are elder than 6 years. HIV infection can significantly affect the children's immune system function,growth and development.%目的 研究15岁以下AIDS患者的临床特点,了解HIV对患儿的影响.方法 分析275例即将入选接受高效抗反转录病毒治疗患者的临床资料,对人口学、流行病学、临床分期、实验室特点及生长发育状况进行分析.结果 275例AIDS患者主要以母婴途径传播为主,占78.9%,输血及血制品传播的为16.0%.平均年龄(7.6±3.7)岁,其中1岁以内5例,1~5岁104例,6

  8. Demographic and injury characteristics of spinal cord injury in 275 children%儿童脊髓损伤275例人口学与损伤特点

    Institute of Scientific and Technical Information of China (English)

    王一吉; 周红俊; 卫波; 刘根林; 郑樱; 郝春霞; 张缨; 康海琼; 袁媛

    2015-01-01

    目的 分析14岁以下儿童脊髓损伤住院患者人口学和损伤特点,为儿童脊髓损伤防治提供依据.方法 对1989年1月至2014年12月中国康复研究中心收治的275例14岁以下儿童脊髓损伤患者的性别、年龄、致伤原因、受伤日期及损伤情况等资料进行回顾性分析.结果 275例患儿中,男111例(40.4%),女164例(59.6%).4.0~7.0岁年龄组患儿最多(48.0%,132/275例),其中女93例(70.5%,93/132例).致伤原因中前3位分别是交通事故损伤74例(26.9%)、非外伤性损伤72例(26.2%)、体育运动损伤70例(25.5%).2003年至2014年最主要的致伤原因为体育运动损伤(28.0%,65/232例),远高于1987至2002年(11.6%,5/43例),差异有统计学意义(x2 =5.135,P=0.023).体育运动损伤中男女比例差距最大(男7例,女63例).4.0 ~7.0岁年龄组最主要的致伤原因是体育运动损伤(48.2%,55/114例).外伤性脊髓损伤中无骨折脱位型脊髓损伤141例(69.5%,141/203例),脊柱骨折62例(30.5%,62/203例);无骨折脱位型脊髓损伤中主要为胸髓损伤(85.8%,121/141例),4.0 ~7.0岁的患儿最多(64.5%,78/121例),体育运动损伤是其最常见的致伤原因(64.1%,50/78例).最早1例体育运动损伤发生在1995年,从2001年开始全国范围内每年都有发生.体育运动损伤以脊柱过伸损伤为主(90.0%,63/70例),夏秋季多见,主要为无骨折脱位型脊髓损伤(98.4%,62/63例),胸髓完全性损伤最多(75.8%,47/62例).结论 体育运动损伤是中国康复研究中心近12年来住院脊髓损伤患儿的主要致伤原因,发病有增多趋势,以4.0~7.0岁女童最多,其原因与舞蹈练习脊柱过伸有关,且大多为胸髓完全性损伤,损伤程度较重,应引起临床高度重视.重点防护人群为练习舞蹈下腰动作的儿童.%Objective To study the demographic and injury characteristics of pediatric spinal cord injury (SCI) in children less than 14 years old in order to

  9. Design and Evaluation of 275 kV-3 kA HTS Power Cable

    Science.gov (United States)

    Yagi, M.; Mukoyama, S.; Mitsuhashi, T.; Jun, T.; Liu, J.; Nakayama, R.; Hayakawa, N.; Wang, X.; Ishiyama, A.; Amemiya, N.; Hasegawa, T.; Saitoh, T.; Ohkuma, T.; Maruyama, O.

    A 275 kV 3 kA high temperature superconducting (HTS) cable has been developed in the Materials & Power Applications of Coated Conductors (M-PACC) project. The cable is expected to be put to practical use as the backbone power line in the future because the capacity of 1.5 GW is about the same as overhead transmission lines. The 30 m cable has been designed on the basis of design values that had been obtained by various voltage tests, AC loss measurement tests, short circuit tests, and other elementary tests. Cable insulation was determined by the design stresses and test conditions based on IEC, JEC (Japan electrical standards), and other HTS demonstrations. This cable was also designed to withstand the short circuit test of 63 kA for 0.6 seconds and to have low losses, including AC loss and dielectric loss of 0.8 W/m at 3kA, 275 kV. Based on the design, a 30 m cable was manufactured, and short samples during this manufacturing process were confirmed to have the designed characteristics. Furukawa Electric prepared a demonstration of the 30 m cable with two terminations and a cable joint. The long-term test under a current of 3 kA, and test voltage determined from 30 years of insulation degradation has been conducted since November 2012 at Shenyang in China.

  10. Autopsy study of 275 medical dispute cases%医疗纠纷275例尸体解剖分析

    Institute of Scientific and Technical Information of China (English)

    谢志刚; 郑杰

    2009-01-01

    目的 探讨医疗纠纷死亡病例的特点,尤其是尸体解剖量、医院、科室、年龄及死亡原因分布特点,为完善医疗纠纷尸体解剖工作提供经验.方法 对北京大学医学部病理学系2002年1月1日至2008年9月30日275例医疗纠纷尸体解剖病例进行回顾性分析.结果 2002年1月1日至2008年9月30日,医疗纠纷尸体解剖逐年增加,二三级医院的外科、妇产科及一级医院的门急诊为死亡纠纷好发科室,1岁以内围生期胎儿及幼童死亡病例比其他年龄组死亡病例更易导致纠纷,国际疾病分类表(ICD10)中心血管系统疾病、围生期疾患、外伤或医疗过程附加因素三个大类在纠纷病例死亡原因多于其他大类.绝大多数死亡是疾病自然转归的结果,医疗过失行为与患者死亡存在密切关系的病例只占13.5%(37/275).对冠心病猝死、心肌梗死和病毒性心肌炎等的病理诊断应严格掌握诊断标准.结论 医疗纠纷尸体解剖可以明确死因,保留证据,对解决纠纷至关重要.严谨细致的操作、规范的诊断及死因分析是做好医疗纠纷尸体解剖工作的关键.%Objective To study the characteristics of autopsies in medical dispute cases, with respect to class of hospitals, clinical units concerned, age of deceased and cause of death. Methods Two hundred and seventy-five autopsies performed on medical dispute cases during the period from January 1, 2002 to September 30, 2008 at the Department of Pathology, Health Science Center, Peking University, China were retrospectively reviewed. Results During the period of study, the number of autopsies performed on medical dispute cases gradually increased. Medical dispute cases happened more often in surgical, obstetric and gynecology departments of grade Ⅱ and Ⅲ hospitals, as well as emergency departments of grade Ⅰ hospitals. Perinatal death in infants of less than 1 year old more frequently caused medical dispute than death

  11. Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells

    Institute of Scientific and Technical Information of China (English)

    Viola Baradari; Michael H(o)pfner; Alexander Huether; Detlef Schuppan; Hans Scherübl

    2007-01-01

    AIM: To investigate the antiproliferative effect of the histone deacetylase (HDAC) inhibitor MS-275 on cholangiocarcinoma cells alone and in combination with conventional cytostatic drugs (gemcitabine or doxorubicin)or the novel anticancer agents sorafenib or bortezomib.METHODS: Two human bile duct adenocarcinoma cell lines (EGI-1 and TFK-1) were studied. Crystal violet staining was used for detection of cell number changes.Cytotoxicity was determined by measuring the release of the cytoplasmic enzyme lactate dehydrogenase (LDH).Apoptosis was determined by measuring the enzyme activity of caspase-3. Cell cycle status reflected by the DNA content was detected by flow cytometry.RESULTS: MS-275 treatment potently inhibited the proliferation of EGI-1 and TFK-1 cholangiocarcinoma cells by inducing apoptosis and cell cycle arrest. MS-275-induced apoptosis was characterized by activation of caspase-3, up-regulation of Bax and down-regulation of Bcl-2. Cell cycle was predominantly arrested at the G1/S checkpoint, which was associated with induction of the cyclin-dependent kinase inhibitor p21Waf/CIP1. Furthermore,additive anti-neoplastic effects were observed when MS-275 treatment was combined with gemcitabine or doxorubicin, while combination with the multikinase inhibitor sorafenib or the proteasome inhibitor bortezomib resulted in overadditive anti-neoplastic effects.CONCLUSION: The growth of human cholangiocarcinoma cells can be potently inhibited by MS-275 alone or in combination with conventional cytostatic drugs or new,targeted anticancer agents.

  12. 从技术层面上解析27.5kV专用电缆的构造特性%Technical Analysis of Formation of 27.5 kV Special Cable

    Institute of Scientific and Technical Information of China (English)

    邱汉忠

    2012-01-01

    27.5 kV single phase copper core XLPE cable for electrified railway,as an indispensible product for the development of electrified railway is introduced in terms of the selection of material,section,insulation,metal screen.%27.5 kV电气化铁道单相铜芯交联聚乙烯绝缘电缆,是电气化铁路发展中必不可少的产品,对电缆导体的材质、截面、绝缘、金属屏蔽的选择进行了介绍。

  13. l275np.m77t - MGD77 data file for Geophysical data from feld activity L-2-75-NP in Gulf of Alaska from 08/25/1975 to 09/04/1975

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Single-beam bathymetry and magnetics data along with DGPS navigation data was collected as part of field activity L-2-75-NP in Gulf of Alaska from 08/25/1975 to...

  14. Lead-Free Double-Base Propellant for the 2.75 Inch Rocket Motor

    Science.gov (United States)

    Magill, B. T.; Nauflett, G. W.; Furrow, K. W.

    2000-01-01

    The current MK 66 2.75 inch Rocket Motor double-base propellant contains the lead-based ballistic modifier LC-12-15 to achieve the desired plateau and mesa burning rate characteristics. The use of lead compounds poses a concern for the environment and for personal safety due to the metal's toxic nature when introduced into the atmosphere by propellant manufacture, rocket motor firing, and disposal. Copper beta-resorcylate (copper 2,4-di-hydroxy-benzoate) was successfully used in propellant as a simple modifier in the mid 1970's. This and other compounds have also been mixed with lead salts to obtain more beneficial ballistic results. Synthesized complexes of lead and copper compounds soon replaced the mixtures. The complexes incorporate the lead, copper lack of organic liquids, which allows for easier propellant processing. About ten years ago, the Indian Head Division, Naval Surface Warfare Center (NSWC), initiated an effort to develop a lead-free propellant for use in missile systems. Several lead-free propellant candidate formulations were developed. About five years ago, NSWC, in conjunction with Alliant Techsystems, Radford Army Ammunition Plant, continued ballistic modifier investigations. A four component ballistic modifier system without lead for double-base propellants that provide adequate plateau and mesa burn rate characteristics was developed and patented. The ballistic modifier's system contains bismuth subsalicylate, 1.5 percent; copper salicylate, 1.0 percent, copper stannate, 0.77 percent; and carbon black, 0.1 percent. Action time and impulse data obtained through multiple static firings indicate that the new lead-free double-base propellant, while not a match for NOSIH-AA-2, will be a very suitable replacement in the 2.75 inch Rocket Motor. Accelerated aging of the double-base propellant containing the lead-free ballistic modifier showed that it had a much higher rate of stabilizer depletion than the AA-2. A comprehensive study showed that an

  15. 49 CFR 178.275 - Specification for UN Portable Tanks intended for the transportation of liquid and solid hazardous...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Specification for UN Portable Tanks intended for... Portable Tanks § 178.275 Specification for UN Portable Tanks intended for the transportation of liquid and... definitions and requirements that apply to UN portable tanks intended for the transportation of liquid...

  16. 42 CFR 137.275 - May Self-Governance Tribes include IHS construction programs in a construction project agreement...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false May Self-Governance Tribes include IHS construction... OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Purpose and Scope § 137.275 May Self-Governance Tribes include IHS construction programs in a construction project agreement or in a...

  17. Production of polyclonal antiserum specific to the 27.5 kDa envelope protein of white spot syndrome virus

    NARCIS (Netherlands)

    You, Z.O.; Nadala, E.C.B.; Yang, J.S.; Hulten, van M.C.W.; Loh, P.C.

    2002-01-01

    A truncated version of the white spot syndrome virus (WSSV) 27.5 kDa envelope protein was expressed as a histidine tag fusion protein in Escherichia coli. The bacterial expression system allowed the production of up to 10 mg of purified recombinant protein per liter of bacterial culture. Antiserum f

  18. Dead or Alive? Long-time evolution of SN 2015bh (SNhunt275)

    CERN Document Server

    Elias-Rosa, N; Benetti, S; Cappellaro, E; Taubenberger, S; Terreran, G; Fraser, M; Brown, P J; Tartaglia, L; Morales-Garoffolo, A; Harmanen, J; Tomasella, L; Margutti, R; Smartt, S J; Dennefeld, M; Turatto, M; Anupama, G C; Arbour, R; Berton, M; Boles, T; Chornock, R; Briganti, F; Ciabattari, F; Cortini, G; Dimai, A; Itagaki, K; Kamble, A; Kotak, R; Mancini, R; Martinelli, F; Milisavljevic, D; Misra, K; Ochner, P; Patnaude, D; Polshaw, J; Sahu, D K; Zaggia, S

    2016-01-01

    Supernova (SN) 2015bh (or SNhunt275) was discovered in NGC 2770 on 2015 February with an absolute magnitude of Mr ~ -13 mag, and was initially classified as a SN impostor. Here we present the photometric and spectroscopic evolution of SN 2015bh from discovery to late phases (~ 1 yr after). In addition, we inspect archival images of the host galaxy up to ~ 16 yr before discovery, finding a burst ~ 1 yr before discovery, and further signatures of stellar instability until late 2014. Later on, the luminosity of the transient slowly increases, and a broad light curve peak is reached after about three months. We propose that the transient discovered in early 2015 could be a core-collapse SN explosion. The pre-SN luminosity variability history, the long-lasting rise and faintness first light curve peak suggests that the progenitor was a very massive, unstable and blue star, which exploded as a faint SN because of severe fallback of material. Later on, the object experiences a sudden brightening of 3 mag, which resu...

  19. Multimodality treatment of brain metastases: an institutional survival analysis of 275 patients

    Directory of Open Access Journals (Sweden)

    Demakas John J

    2011-07-01

    Full Text Available Abstract Background Whole brain radiation therapy (WBRT, surgical resection, stereotactic radiosurgery (SRS, and combinations of the three modalities are used in the management of patients with metastatic brain tumors. We present the previously unreported survival outcomes of 275 patients treated for newly diagnosed brain metastases at Cancer Care Northwest and Gamma Knife of Spokane between 1998 and 2008. Methods The effects treatment regimen, age, Eastern Cooperative Oncology Group-Performance Status (ECOG-PS, primary tumor histology, number of brain metastases, and total volume of brain metastases have on patient overall survival were analyzed. Statistical analysis was performed using Kaplan-Meier survival curves, Andersen 95% confidence intervals, approximate confidence intervals for log hazard-ratios, and multivariate Cox proportional hazard models. Results The median clinical follow up time was 7.2 months. On multivariate analysis, survival statistically favored patients treated with SRS alone when compared to patients treated with WBRT alone (p Conclusions In our analysis, patients benefited from a combined modality treatment approach and physicians must consider patient age, performance status, and primary tumor histology when recommending specific treatments regimens.

  20. "Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183"

    NARCIS (Netherlands)

    Marchetti, Serena; Pluim, Dick; Beijnen, Jos H; Mazzanti, Roberto; van Tellingen, Olaf; Schellens, Jan H M

    2014-01-01

    BMS-275,183 is a novel oral C-4 methyl carbonate analogue of paclitaxel. Recently, a drug-drug interaction between BMS-275,183 and benzimidazole proton pump inhibitors (PPIs) was suggested in clinical trials resulting in elevated drug exposure and toxicity. We explored whether the interaction takes

  1. The basis for fibrinogen Cedar Rapids ({gamma}R275C) fibrin network structure

    Energy Technology Data Exchange (ETDEWEB)

    DiOrio, J.P. [Baxter Healthcare Corp., Round Lake, IL (United States); Mosesson, M.W.; Siebenlist, K.R. [Univ. Wisconsin Medical School-Milwaukee Clinic Campus, WI (United States)] [and others

    1996-12-31

    Fibrinogen `Cedar Rapids` is a heterozygous dysfibrinogenemia characterized by delayed and abnormal fibrin polymerization. The specific molecular defect ({gamma}R275C) is relatively common, but in only one case, fibrinogen Tokyo II, has the ultrastructural basis for defective clot formation been determined. This report reflects similar structural studies on Cedar Rapids fibrinogen and fibrin. Crosslinked fibrinogen molecules and fibrils, were prepared at 1 mg/ml in the presence of factor XIIIa (100 u/ml). When {gamma} chains had become {approximately}10 to 20% crosslinked to {gamma} dimers, samples were diluted with Hepes buffered saline, pH 7, to a fibrinogen concentrated of 5 to 10 {mu}g/ml. Three {mu}l was then injected into 3 {mu}l buffer on a carbon-coated EM grid, the specimen allowed to attach for one minute, fluid-exchanged several times with 150 mM NH{sub 4} acetate solution, frozen in liquid nitrogen, freeze-dried, and imaged at the Brookhaven STEM facility using a 40 kv probe focused at 0.25 nm. Fibrin for scanning EM (SEM) was formed directly on carbon-formvar coated gold grids. Clots that had formed overnight were fixed with 2.5% glutaraldehyde in 0.1 M Hepes, pH 7 buffer containing 0.2% tannic acid, washed with buffer, dehydrated, CO{sub 2} critical point dried, coated with 7.5 nm platinum, and imaged in a JOEL Field Emission SEM operated at 5 kV.

  2. Eleven-Year Retrospective Survival Study of 275 Veneered Lithium Disilicate Single Crowns.

    Science.gov (United States)

    Simeone, Piero; Gracis, Stefano

    2015-01-01

    The aim of the present clinical retrospective study was to evaluate the long-term survival and clinical performance of veneered lithium disilicate single restorations in anterior and posterior areas after up to 11 years. Following a rigid protocol, 275 lithium disilicate single crowns (35 IPS Empress II and 240 e.max Press) were cemented over 11 years, in 106 patients, using an adhesive technique; of these 106 were anterior (38.5%) and 169 posterior (61.5%) teeth. Teeth receiving endodontic therapy and composite reconstruction (50%) and teeth with preexisting metalceramic crowns, called prosthetic retreatments (PR; 65%), were included as well. Of the 106 patients enrolled in the study, 25 (23.5%) were diagnosed with bruxism habits, and 7 of these patients (6.6% of all patients) received full-mouth single lithium disilicate restorations (FMR). The exclusion criteria for this retrospective clinical study were: monolithic lithium disilicate crowns, teeth with cast post and cores, implant-supported all-ceramic crowns, active periodontitis, and/or poor oral hygiene. Clinical reevaluation was performed by the clinicians who prepared and luted them during maintenance appointments between January 2012 and October 2013. Number of restoration failures and characteristics of failures were recorded. Marginal adaptation and marginal discoloration were evaluated based on the Cvar-Ryge criteria. The overall cumulative survival rate was 98.2%. The failures recorded were the result of either mechanical failure or debonding. Five crowns failed mechanically-three because of chipping and two because of core fracture-and were replaced. None of the failed crowns was associated with the bruxers with FMR. A total of 15 crowns debonded (5.5% of all crowns); however, 11 belonged to the same patient who had endodontically treated and reconstructed abutments. In this retrospective clinical evaluation of up to 132 months, veneered lithium disilicate single crowns had a low failure rate.

  3. Rotator cuff tears: assessment with MR arthrography in 275 patients with arthroscopic correlation

    Energy Technology Data Exchange (ETDEWEB)

    Waldt, S.; Bruegel, M.; Mueller, D.; Holzapfel, K.; Rummeny, E.J.; Woertler, K. [Technische Universitaet Muenchen, Department of Radiology, Munich (Germany); Imhoff, A.B. [Technische Universitaet Muenchen, Department of Sports Orthopedics, Munich (Germany)

    2007-02-15

    We assessed the diagnostic performance of magnetic resonance (MR) arthrography in the diagnosis of articular-sided partial-thickness and full-thickness rotator cuff tears in a large symptomatic population. MR arthrograms obtained in 275 patients including a study group of 139 patients with rotator cuff tears proved by arthroscopy and a control group of 136 patients with arthroscopically intact rotator cuff tendons were reviewed in random order. MR imaging was performed on a 1.0 T system (Magnetom Expert, Siemens). MR arthrograms were analyzed by two radiologists in consensus for articular-sided partial-thickness and full-thickness tears of the supraspinatus, infraspinatus, and subscapularis tendons. At arthroscopy, 197 rotator cuff tears were diagnosed, including 105 partial-thickness (93 supraspinatus, nine infraspinatus, three subscapularis) and 92 full-thickness (43 supraspinatus, 20 infraspinatus, 29 subscapularis) tendon tears. For full-thickness tears, sensitivity, specificity, and accuracy were 96%, 99%, and 98%, respectively, and for partial tears 80%, 97%, and 95%, respectively. False negative and positive assessments in the diagnosis of articular-sided partial-thickness tears were predominantly [78% (35/45)] observed with small articular-sided (Ellman grade1) tendon tears. MR arthrography is highly accurate in the diagnosis of full-thickness rotator cuff tears and is accurate in the diagnosis of articular-sided partial-thickness tears. Limitations in the diagnosis of partial-thickness tears are mainly restricted to small articular-sided tears (Ellman grade 1) due to difficulties in differentiation between fiber tearing, tendinitis, synovitic changes, and superficial fraying at tendon margins. (orig.)

  4. A novel presenilin 1 mutation (Ala275Val) as cause of early-onset familial Alzheimer disease.

    Science.gov (United States)

    Luedecke, Daniel; Becktepe, Jos S; Lehmbeck, Jan T; Finckh, Ulrich; Yamamoto, Raina; Jahn, Holger; Boelmans, Kai

    2014-04-30

    Mutations in the presenilin 1 (PS1) gene (PSEN1) are associated with familial Alzheimer disease (FAD). Here, we report on a 50-year-old patient presenting with progressive deterioration of his short-term memory and a family history of early-onset dementia. Diagnostic workup included a neuropsychological examination, structural magnetic resonance (MR) imaging, cerebrospinal fluid (CSF) biomarkers including total tau, phosphorylated tau, and Aβ42 levels, as well as sequencing relevant fragments of the genes PSEN1, PSEN2, and APP. Additionally, we were able to obtain archival paraffin-embedded cerebellar tissue from the patient's father for cosegregation analysis. Clinical, neuropsychological and MR imaging data were indicative of early-onset Alzheimer disease. Furthermore, CSF biomarkers showed a typical pattern for Alzheimer disease. DNA sequencing revealed a heterozygous nucleotide transition (c.824C>T) in exon 8 of PSEN1, leading to an amino acid change from alanine to valine at codon 275 (Ala275Val). The same mutation was found in an archival brain specimen of the patient's demented father, but not in a blood sample of the non-demented mother. This mutation alters a conserved residue in the large hydrophilic loop of PS1, suggesting pathogenic relevance. Cosegregegation analysis and the structural as well as the presumed functional role of the mutated and highly conserved residue suggest FAD causing characteristics of the novel PSEN1 mutation Ala275Val.

  5. Spin excitations in stripe-ordered La{sub 2-x}Sr{sub x}NiO{sub 4} (x=0.275 and ((1)/(3)))

    Energy Technology Data Exchange (ETDEWEB)

    Boothroyd, A.T. E-mail: a.boothroyd1@physics.ox.ac.uk; Freeman, P.G.; Prabhakaran, D.; Woo, H.; Nakajima, K.; Tranquada, J.M.; Yamada, K.; Frost, C.D

    2004-05-01

    We report neutron scattering measurements of the spectrum of magnetic excitations in the stripe-ordered phase of La{sub 2-x}Sr{sub x}NiO{sub 4} (x=0.275 and ((1)/(3))). The propagating spin excitations follow a similar dispersion relation for the two compositions, but the line widths are broader for x=0.275 than for ((1)/(3))

  6. Spin excitations in stripe-ordered La 2- xSr xNiO 4 ( x=0.275 and {1}/{3})

    Science.gov (United States)

    Boothroyd, A. T.; Freeman, P. G.; Prabhakaran, D.; Woo, H.; Nakajima, K.; Tranquada, J. M.; Yamada, K.; Frost, C. D.

    2004-05-01

    We report neutron scattering measurements of the spectrum of magnetic excitations in the stripe-ordered phase of La 2- xSr xNiO 4 ( x=0.275 and {1}/{3}). The propagating spin excitations follow a similar dispersion relation for the two compositions, but the line widths are broader for x=0.275 than for {1}/{3}.

  7. Lambda0 polarization in p p ---> p Lambda0 K+ (pi+ pi-) at 27.5-GeV

    Energy Technology Data Exchange (ETDEWEB)

    Felix, J.; Christian, D.C.; Church, M.D.; Forbush, M.; Gottschalk, E.E.; Gutierrez, G.; Hartouni, E.P.; Holmes, Stephen D.; Huson, F.R.; Jensen, D.A.; Knapp, B.C.; Kreisler, M.N.; Uribe, J.; Stern, B.J.; Wang, M.H.L.S.; Wehmann, A.; Wiencke, L.R.; White, J.T.; /Guanajuato U. /Fermilab /Nevis Labs, Columbia U. /Texas A-M /Massachusetts U.,

    2004-10-01

    The polarization of 1973 {Lambda}{sup 0}'s from the specific reaction pp {yields} p{Lambda}{sup 0}K{sup +}({pi}{sup +}{pi}{sup -}){sup 5} created by 27.5 Gev incident protons on a liquid hydrogen target, as a function of {chi}{sub F}, P{sub T}, and M{sub {Lambda}{sup 0}K{sup +}}, is, within statistics, consistent with the polarization of {Lambda}{sup 0}'s from pp {yields} P{sub fast} {Lambda}{sup 0}K{sup +} at 800 GeV.

  8. A Novel Electrical Insulating Material for 275 kV High-Voltage HTS Cable with Low Dielectric Loss

    Science.gov (United States)

    Hayakawa, N.; Nishimachi, S.; Maruyama, O.; Ohkuma, T.; Liu, J.; Yagi, M.

    2014-05-01

    In the case of high temperature superconducting (HTS) power transmission cables at high voltage operation, the electrical insulation technique in consideration of the dielectric loss reduction becomes crucial. In this paper, we focused on a Tyvek/polyethylene (PE) sheet, instead of the conventional polypropylene laminated paper (PPLP). We obtained the dielectric characteristics (epsilonr, tanδ) and partial discharge inception strength (PDIE) of PPLP, Tyvek and Tyvek/PE. We pointed out that the dielectric loss of 275 kV HTS cable with Tyvek/PE insulation will be reduced to 21 % of that with PPLP, and the total electrical loss including the AC loss will be reduced to 41 %.

  9. Gravitational quantization of exoplanet orbits in HD 40307, $\\mu$ Ara, Kepler-26, Kepler-62, and Kepler-275: Comparing predicted orbits

    CERN Document Server

    Geroyannis, Vassilis S

    2015-01-01

    According to the so-called "global polytropic model", hydrostatic equilibrium for a planetary system leads to the Lane-Emden differential equation. Solving this equation in the complex plane, we obtain polytropic spherical shells defined by succesive roots of the real part $\\mathrm{Re}(\\theta)$ of the Lane-Emden function $\\theta$. Such shells provide hosting orbits for the members of a planetary system. Within the framework of the global polytropic model, we study the exoplanet systems HD 40307, $\\mu$ Ara, Kepler-26, Kepler-62, and Kepler-275. We give emphasis on comparing our results with observations, and with orbit predictions derived from the "generalized Titius-Bode relation".

  10. "Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183".

    Science.gov (United States)

    Marchetti, Serena; Pluim, Dick; Beijnen, Jos H; Mazzanti, Roberto; van Tellingen, Olaf; Schellens, Jan H M

    2014-12-01

    BMS-275,183 is a novel oral C-4 methyl carbonate analogue of paclitaxel. Recently, a drug-drug interaction between BMS-275,183 and benzimidazole proton pump inhibitors (PPIs) was suggested in clinical trials resulting in elevated drug exposure and toxicity. We explored whether the interaction takes place at the level of P-glycoprotein (Pgp, MDR1, ABCB1), Breast Cancer Resistance Protein (BCRP, ABCG2) and MRP2 (ABCC2) using in vitro and in vivo models. In vitro cell survival, drug accumulation, efflux and transport studies with BMS-275,183 were performed employing MDCKII (wild-type, MDR1, BCRP, MRP2) and LLCPK (wild-type and MDR1) cells. In vivo the pharmacokinetics and tissue distribution of BMS-275,183 after p.o. and i.v. administration were explored in Mdr1a/1b(-/-) and wild-type mice, in presence or absence of the PPI pantoprazole. Results In vitro, BMS-275,183 was found to be a good substrate for MDR1, a moderate substrate for MRP2 and not a substrate for BCRP. In vivo, oral bioavailability, plasma AUC0-6h and brain concentrations were significantly 1.5-, 4-, and 2-fold increased, respectively, in Mdr1a/1b(-/-) compared with wild-type mice (p < 0.001). However, oral co-administration of pantoprazole (40 mg/kg) did not alter the pharmacokinetics of BMS-275,183 in wild-type mice. Conclusions BMS-275,183 is efficiently transported by Pgp and to a lesser extent by MRP2 in vitro. Genetic deletion of Pgp significantly altered the pharmacokinetics and brain distribution of p.o. and i.v. administered BMS-275,183 in Mdr1a/1b-/- compared to wild-type mice. Oral co-administration of BMS-275,183 with pantoprazole did not affect the pharmacokinetics of BMS-275,183 in wild-type mice, suggesting no interaction with PPI at the dose employed.

  11. The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients.

    Science.gov (United States)

    Brouns, Elisabeth-R E A; Baart, Jacques-A; Bloemena, Elisabeth; Karagozoglu, Hakki; van der Waal, Isaäc

    2013-01-01

    The aim of the present study was to evaluate the definition of oral leukoplakia, proposed by the WHO in 2005 and taking into account a previously reported classification and staging system, including the use of a Certainty factor of four levels with which the diagnosis of leukoplakia can be established. In the period 1997-2012 a hospital-based population of 275 consecutive patients with a provisional diagnosis of oral leukoplakia has been examined. In only 176 patients of these 275 patients a firm diagnosis of leukoplakia has been established based on strict clinicopathological criteria. The 176 patients have subsequently been staged using a classification and staging system based on size and histopathologic features. For use in epidemiological studies it seems acceptable to accept a diagnosis of leukoplakia based on a single oral examination (Certainty level 1). For studies on management and malignant transformation rate the recommendation is made to include the requirement of histopathologic examination of an incisional or excisional biopsy, representing Certainty level 3 and 4, respectively. This recommendation results in the following definition of oral leukoplakia: "A predominantly white lesion or plaque of questionable behaviour having excluded, clinically and histopathologically, any other definable white disease or disorder". Furthermore, we recommend the use of strict diagnostic criteria for predominantly white lesions for which a causative factor has been identified, e.g. smokers' lesion, frictional lesion and dental restoration associated lesion.

  12. VizieR Online Data Catalog: PTF obs. of a precursor to SNHunt 275 2015 May event (Ofek+, 2016)

    Science.gov (United States)

    Ofek, E. O.; Cenko, S. B.; Shaviv, N. J.; Duggan, G.; Strotjohann, N.-L.; Rubin, A.; Kulkarni, S. R.; Gal-Yam, A.; Sullivan, M.; Cao, Y.; Nugent, P. E.; Kasliwal, M. M.; Sollerman, J.; Fransson, C.; Filippenko, A. V.; Perley, D. A.; Yaron, O.; Laher, R.

    2016-08-01

    The Palomar Transient Factory (PTF and iPTF; Law et al. 2009PASP..121.1395L; Rau et al. 2009PASP..121.1334R), using the 48inch Oschin Schmidt telescope, observed the field of SNHunt 275 starting in 2009 March. On 2013 December 12, PTF detected a new source at the location of the event, and the transient was named PTF 13efv (see Figure 1). Three images obtained between 2014 January 23 and April 25 were used as a reference. The PTF R-band photometry is listed in Table1. Most of the optical spectra were obtained with the Low Resolution Imaging Spectrometer (LRIS) on the Keck I 10m telescope, although a few spectra were also taken with the DEep Imaging Multi-Object Spectrograph (DEIMOS) on the Keck II 10m telescope, the Kast spectrograph on the Shane 3m telescope at Lick Observatory, and the Gemini-North Multiobject Spectrograph (GMOS) on the 8m Gemini-N telescope. The first spectrum was obtained during the 2013 December outburst. We used the Swift/UVOT observations of SNHunt 275, since 2008, to construct the bolometric light curve of the transient. The log of Swift-XRT observations, along with the source and background X-ray counts in the individual observations, is given in Table 5. (3 data files).

  13. EtiOlOgy and clinical analysis Of 275 admitted children with hypertensiOn%275例住院儿童高血压的病因及临床分析

    Institute of Scientific and Technical Information of China (English)

    张仪; 张清友; 张春雨; 闫辉; 齐建光; 肖慧捷; 姚勇; 刘雪芹; 陈永红; 钟旭辉; 王芳; 管娜

    2014-01-01

    Objective This study pursues to analyze the independent risk factors in primary and secondary hyperten-sion, and to provide the references for the diagnosis and differential diagnosis of hypertension in children. MethOd The clinical data of 275 inpatient children in the Pediatrics Department of Peking University First Hospital were ret-rospectively reviewed. The Logistic regression analysis was used to find out the risk factors for primary and seconda-ry hypertension. Result In these 275 patients, the most common symptoms are headache and dizziness(34%), and 45. 7% patients have no symptoms. After our calculation by Logistic multivariable regression analysis, the inde-pendent risk factors of primary hypertension are Hypertension family history and BMI overload, but the independent risk factor of secondary hypertension is proteinuria. COnclusiOn The most common symptoms of hypertension are dizziness and headache in children, but many children with hypertension have no symptoms. Hypertension family history and BMI overload indicates primary hypertension, proteinuria indicates secondary hypertension in children with hypertension.%目的:分析原发性及继发性高血压的危险因素,为儿童高血压的诊断和鉴别诊断提供参考依据。方法回顾性总结275例住院高血压患儿的临床资料, Logistic回归分析原发性和继发性高血压的危险因素。结果高血压患儿最常见的症状为头痛、头晕,占34%;约45.7%的病例无临床症状。经逐步向前引入剔除,Logistic回归多因素分析显示,高血压家族史、体重指数( BMI)升高为原发性高血压的独立危险因素,蛋白尿为继发性高血压的独立危险因素。结论儿童高血压以头晕、头痛为最常见症状,但相当比例的患儿隐匿起病,无临床症状。儿童高血压伴随高血压家族史、BMI升高提示原发性高血压,伴随蛋白尿提示继发性高血压。

  14. A microstructural investigation of gas atomized Raney type Al-27.5 at.% Ni catalyst precursor alloys

    Energy Technology Data Exchange (ETDEWEB)

    Mullis, A.M., E-mail: a.m.mullis@leeds.ac.uk [Institute for Materials Research, University of Leeds, Leeds LS2 9JT (United Kingdom); Bigg, T.D., E-mail: t.bigg@leeds.ac.uk [Institute for Materials Research, University of Leeds, Leeds LS2 9JT (United Kingdom); Adkins, N.J., E-mail: n.j.e.adkins@bham.ac.uk [IRC in Materials Processing, University of Birmingham, Edgbaston, Birmingham B15-2TT (United Kingdom)

    2015-11-05

    Quantitative image analysis has been used to investigate the phase composition of gas atomized powders of a Raney type Ni catalyst precursor alloys of composition Al-27.5 at.% Ni in the powder size range 150–212 μm. We find that there are considerable variations in phase composition both between powders from the same batch and as a function distance from the particle surface within individual particles. Such variations may have significant implications for the future production and uptake of such catalysts, including the necessity for post-production crushing of gas atomized powders. Models are proposed to account for both variations. - Highlights: • The phase composition of powder Raney-Ni catalysts has been investigated. • Image analysis is used to quantify differences between and within particles. • Phase composition can vary by up to 10% between the particle surface and centre. • Differences of up to 10% in the mean composition are also found between particles.

  15. Cytogenetic characteristics of B cell chronic lymphocytic leukemia in 275 Chinese patients by fluorescence in situ hybridization: a multicenter study

    Institute of Scientific and Technical Information of China (English)

    LAI Yue-yun; HUANG Xiao-jun

    2011-01-01

    Background Under conventional cytogenetic (CC) analysis, only 30%-50% of B cell chronic lymphocytic leukemia (B-CLL) cases show clonal aberrations. Using fluorescence in situ hybridization (FISH), the percentage of patients with abnormalities rises to almost 80%, among them, the most frequent abnormalities were 13q14, 11q22, p53 deletions and trisomy 12. The aim of this study was to explore the incidence of cytogenetic changes in Chinese patients with B-CLL.Methods We used FISH methods to detect the cytogenetic features in 275 cases of B-CLL from 48 hospitals. The correlation between FISH abnormalities and clinical characteristics such as age, gender, white blood cell count,peripheral hemoglobin (Hb) level, peripheral platelet count (PLT), lactate dehydrogenase (LDH) level, Rai stage, Binet stage, and overall survival was analyzed, and the relationship between them and overall survival was also analyzed to evaluate their prognostic implications.Results Of the 275 patients, genetic aberrations were found in 77.8% using FISH. The frequencies of abnormalities were as follows: 13q deletion (56.4%), trisomy 12 (34.5%), p53 deletion (33.5%) and 11q22 deletion (30.5%). It was obvious that the patients with p53 deletion had lower level of Hb (P=0.001) and PLT (P=0.003) when compared to patients without p53 deletion. Significant differences were obtained in the distribution of p53 deletion according to Rai and Binet classification systems (P=0.016 and 0.008 respectively). Significant differences were also observed when the overall survival was correlated with p53 deletion (P=0.043), Rai stage (P=0.006), Binet stage (P=0.013), Hb level (P=0.004) and PLT level (P=0.010).Conclusions Chinese CLL patients have the similar frequencies of del(13q), trisomy 12, del(11q) and a higher frequency of del(17p) when compared to literatures. Del(17p) is associated with advanced stage and low levels of Hb and PLT. Patients with p53 deletion, or advanced stage probably have poor survival in

  16. THE RATIONALE FOR THE USE OF TWO-PHASE SWITCHES FOR THREE-PHASE CONNECTIONS OF DISTRIBUTIVE DEVICE 27.5 KV

    Directory of Open Access Journals (Sweden)

    Yu. Ya. Sheika

    2008-12-01

    Full Text Available On the basis of materials of scientists of Moscow and Petersburg State Universities of C Ways and NIIEFAENERGO Ltd.» the author of this article with additions has considered a practical possibility of us bipolar switches on three-phase connections of distributive device 27,5 кV.

  17. The temperature evolution of the out-of-plane correlation lengths of charge-stripe ordered La1.725Sr0.275NiO4

    DEFF Research Database (Denmark)

    Freeman, P.G.; Christensen, Niels Bech; Prabhakaran, D.;

    2010-01-01

    The temperature dependence of the magnetic order of stripe-ordered La1.725Sr0.275NiO4 is investigated by neutron diffraction. Upon cooling, the widths of the magnetic Bragg peaks are observed to broaden. The degree of broadening is found to be very different for l = odd-integer and l = even-integ...

  18. Pressure effect on crystallization kinetics in Zr46.8Ti8.2Cu7.5Ni10Be27.5 bulk glass

    DEFF Research Database (Denmark)

    Jiang, Jianzhong; Gerward, Leif; Xu, Y.S.

    2002-01-01

    Crystallization kinetics of a Zr46.8Ti8.2Cu7.5Ni10Be27.5 bulk glass in the supercooled liquid region have been investigated by performing in situ high-temperature and high-pressure x-ray diffraction measurements using synchrotron radiation. A pressure-time-temperature-transformation diagram, desc...

  19. Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.

    Science.gov (United States)

    Akarte, Atul Sureshrao; Srinivasan, B P; Gandhi, Sonia; Sole, Sushant

    2012-09-29

    Inhibitors of dipeptidyl peptidase-4 (DPP-IV), a key regulator of the actions of incretin hormones, exert antihyperglycemic effects in type 2 diabetic patients. A major question concerns the potential ability of long term DPP-IV inhibition to have beneficial disease-modifying effects, specifically to attenuate loss of pancreatic β-cell mass due to oxidative stress induced inflammation. Here, we investigated the effects of a potent and selective DPP-4 inhibitor, an analog of vildagliptin (PKF-275-055), on glycemic control, pancreatic β-cell mass, genes and proteins expressions, tumor necrosis factor-alpha, and nitric oxide in an n2-STZ diabetic model of rat with defects in insulin sensitivity and secretion. To induce NIDDM, streptozotocin (STZ) 90 mg/kg was administered i.p. to a group of 2 days old pups. Diabetic rats were administered orally with vildagliptin analog PKF-275-055. Saline treated animals served as diabetic control. Significant and dose-dependent correction of postprandial hyperglycemia was observed in diabetic rats following 8 weeks of chronic therapy. Treatment with PKF-275-055 showed increased the number of insulin-positive β-cells in islets and improved the expressions of genes and proteins are responsible for insulin secretions. In addition, treatment of rats with PKF-275-055 significantly increased insulin content, glycogen content and total proteins content; and decreased the inflammatory markers i.e. nitric oxide and TNF-alpha. The present studies indicate that PKF-275-055 is a novel selective DPP-IV inhibitor having potential to reduce inflammation that might be a potential agent for type 2 diabetes.

  20. Study of {Lambda}{sup 0} polarization in exclusive {ital pp} reactions at 27.5 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Felix, J.; Avilez, C.; Moreno, G. [Universidad de Guanajuato, Leon, Guanajuato (Mexico); Hartouni, E.P.; Jensen, D.A.; Kreisler, M.N.; Uribe, J.; Wang, M.H. [University of Massachusetts, Amherst, Massachusetts (United States); Christian, D.C.; Gutierrez, G.; Holmes, S.D.; Wehmann, A. [Fermilab, Batavia, Illinois (United States); Church, M.D.; Gottschalk, E.E.; Knapp, B.C.; Stern, B.J.; Wiencke, L.R. [Columbia University, Nevis Labs, New York (United States); Forbush, M.; Huson, F.R.; White, J.T. [Department of Physics, Texas AM University, College Station, Texas 77843 (United States)

    1998-10-01

    We report a measurement of the x{sub F} and P{sub T}{Lambda}{sup 0} polarization dependence; {Lambda}{sup 0}{close_quote}s were produced in the specific channels: pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +}{pi}{sup {minus}}, pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}, pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}, and pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}} with 27.5 GeV/c protons incident on a liquid hydrogen target. We find that {Lambda}{sup 0} polarization is independent of the final state. {copyright} {ital 1998 American Institute of Physics.}

  1. CP-Violating Asymmetries in B0 --> pi+ pi- Decays With 275 Million BB-bar Pairs

    CERN Document Server

    Abe, K; Adachi, I; Aihara, H; Akatsu, M; Asano, Y; Aso, T; Aulchenko, V M; Aushev, T; Aziz, T; Bahinipati, S; Bakich, A M; Ban, Y; Barbero, M; Bay, A; Bedny, I; Bitenc, U; Bizjak, I; Blyth, S; Bondar, A; Bozek, A; Bracko, M; Brodzicka, J; Browder, T E; Chang, M C; Chang, P; Chao, Y; Chen, A; Chen, K F; Chen, W T; Cheon, B G; Chistov, R; Choi, S K; Choi, Y; Choi, Y K; Chuvikov, A; Cole, S; Danilov, M; Dash, M; Dong, L Y; Dowd, R; Dragic, J; Drutskoy, A; Eidelman, S; Enari, Y; Epifanov, D A; Everton, C W; Fang, F; Fratina, S; Fujii, H; Gabyshev, N; Garmash, A; Gershon, T; Go, A; Gokhroo, G; Golob, B; Grosse-Perdekamp, M; Guler, H; Haba, J; Handa, F; Hara, K; Hara, T; Hastings, N C; Hasuko, K; Hayasaka, K; Hayashii, H; Hazumi, M; Heenan, E M; Higuchi, I; Higuchi, T; Hinz, L; Hojo, T; Hokuue, T; Hoshi, Y; Hoshina, K; Hou, S; Hou Wei Shu; Hsiung, Y B; Huang, H C; Igaki, T; Igarashi, Y; Iijima, T; Imoto, A; Inami, K; Ishikawa, A; Ishino, H; Itoh, K; Itoh, R; Iwamoto, M; Iwasaki, M; Iwasaki, Y; Kagan, R; Kakuno, H; Kang, J H; Kang, J S; Kapusta, P; Kataoka, S U; Katayama, N; Kawai, H; Kawakami, Y; Kawamura, N; Kawasaki, T; Kent, N; Khan, H R; Kibayashi, A; Kichimi, H; Kim, H J; Kim, H O; Hyunwoo Kim; Kim, J H; Kim, S K; Kim, T H; Kinoshita, K; Koppenburg, P; Korpar, S; Krizan, P; Krokovnyi, P P; Kulasiri, R; Kuo, C C; Kurashiro, H; Kurihara, E; Kusaka, A; Kuzmin, A; Kwon, Y J; Lange, J S; Leder, G; Lee, S E; Lee, S H; Lee, Y J; Lesiak, T; Li, J; Limosani, A; Lin, S W; Liventsev, D; MacNaughton, J; Majumder, G; Mandl, F; Marlow, D; Matsuishi, T; Matsumoto, H; Matsumoto, S; Matsumoto, T; Matyja, A; Mikami, Y; Mitaroff, W A; Miyabayashi, K; Miyabayashi, Y; Miyake, H; Miyata, H; Mizuk, R; Mohapatra, D; Moloney, G R; Moorhead, G F; Mori, T; Murakami, A; Nagamine, T; Nagasaka, Y; Nakadaira, T; Nakamura, I; Nakano, E; Nakao, M; Nakazawa, H; Natkaniec, Z; Neichi, K; Nishida, S; Nitoh, O; Noguchi, S; Nozaki, T; Ogawa, A; Ogawa, S; Ohshima, T; Okabe, T; Okuno, S; Olsen, S L; Onuki, Y; Ostrowicz, W; Ozaki, H; Pakhlov, P; Palka, H; Park, C W; Park, H; Park, K S; Parslow, N; Peak, L S; Pernicka, M; Perroud, Jean-Pierre; Peters, M; Piilonen, L E; Poluektov, A; Ronga, F J; Root, N; Rózanska, M; Sagawa, H; Saigo, M; Saitoh, S; Sakai, Y; Sakamoto, H; Sarangi, T R; Satapathy, M; Sato, N; Schneider, O; Schümann, J; Schwanda, C; Schwartz, A J; Seki, T; Semenov, S; Senyo, K; Settai, Y; Seuster, R; Sevior, M E; Shibata, T; Shibuya, H; Shwartz, B; Sidorov, V; Siegle, V; Singh, J B; Somov, A; Soni, N; Stamen, R; Stanic, S; Staric, M; Sugi, A; Sugiyama, A; Sumisawa, K; Sumiyoshi, T; Suzuki, S; Suzuki, S Y; Tajima, O; Takasaki, F; Tamai, K; Tamura, N; Tanabe, K; Tanaka, M; Taylor, G N; Teramoto, Y; Tian, X C; Tokuda, S; Tovey, Stuart N; Trabelsi, K; Tsuboyama, T; Tsukamoto, T; Uchida, K; Uehara, S; Uglov, T; Ueno, K; Unno, Y; Uno, S; Ushiroda, Y; Varner, G; Varvell, K E; Villa, S; Wang, C C; Wang, C H; Wang, J G; Wang, M Z; Watanabe, M; Watanabe, Y; Widhalm, L; Xie, Q L; Yabsley, B D; Yamaguchi, A; Yamamoto, H; Yamamoto, S; Yamanaka, T; Yamashita, Y; Yamauchi, M; Yang, H; Yeh, P; Ying, J; Yoshida, K; Yuan, Y; Yusa, Y; Yuta, H; Zang, S L; Zhang, C C; Zhang, J; Zhang, L M; Zhang, Z P; Zhilich, V; Ziegler, T; Zontar, D; Zürcher, D

    2005-01-01

    We present a new measurement of the time-dependent CP-violating parameters in B0 --> pi+ pi- decays using a 253 fb-1 data sample that contains 275 x 10^6 BB-bar pairs collected with the Belle detector at the KEKB asymmetric-energy e+e- collider operating at the Upsilon(4S) resonance. We reconstruct one neutral B meson as a pi+ pi- CP eigenstate and identify the flavor of the accompanying B meson from its decay products. We find 666 +/- 43 B0 --> pi+ pi- events and perform an unbinned maximum likelihood fit to the distribution of the proper-time differences between the two B meson decays. The fit yields the CP-violating parameters: S_pipi = -0.67 +/- 0.16(stat) +/- 0.06(syst) and A_pipi = +0.56 +/- 0.12(stat) +/- 0.06(syst). Large direct CP-violation is observed with a significance greater than 4 standard deviations for any S_pipi value. Using isospin relations, we obtain 95.4% confidence intervals for the CKM angle phi_2 of 0 deg. < phi_2 < 19 deg. and 71 deg. < phi_2 < 180 deg.

  2. A 25-year follow-up of cognitive/behavioral therapy with 7,275 sexual offenders.

    Science.gov (United States)

    Maletzky, Barry M; Steinhauser, Cynthia

    2002-04-01

    Outcome data are presented, grouped into 5-year cohorts, for 7,275 sexual offenders entering a cognitive/behavioral treatment program. Assessment variables included treatment completion, self-admission of covert and/or overt deviant behaviors, the presence of deviant sexual arousal, or being recharged for any sexual crime (regardless of plea or conviction). It proved possible to follow 62% for the cohort at 5 years after initiating treatment, but follow-up completion rates decreased with time. Outcomes were significantly different based on offender subtype, with child molesters and exhibitionists achieving better overall success than pedophiles or rapists. Prematurely terminating treatment was a strong indicator of committing a new sexual offense. Of interest was the general improvement of success rates over each successive 5-year period for many types of offenders. Unfortunately, failure rates remained comparatively high for rapists (20%) and homosexual pedophiles (16%), regardless of when they were treated over the 25-year period. Implications for clinical practice and future research are drawn.

  3. PTF 13efv - An outburst 500 days prior to the SNHunt 275 explosion and its radiative efficiency

    CERN Document Server

    Ofek, E O; Shaviv, N J; Duggan, G; Strotjohann, N -L; Rubin, A; Kulkarni, S R; Gal-Yam, A; Sullivan, M; Cao, Y; Nugent, P E; Kasliwal, M M; Sollerman, J; Fransson, C; Filippenko, A V; Perley, D A; Yaron, O; Laher, R

    2016-01-01

    The progenitors of some supernovae (SNe) exhibit outbursts with super-Eddington luminosities prior to their final explosions. This behavior is common among Type IIn SNe, but the driving mechanisms of these precursors are not yet well understood. SNHunt 275 was announced as a possible new SN during May 2015. Here we report on pre-explosion observations of the location of this event by the Palomar Transient Factory (PTF) and report the detection of a precursor about 500 days prior to the 2015 May activity (PTF 13efv). The observed velocities in the 2015 transient and its 2013 precursor absorption spectra are low (1000-2000 km/s), so it is not clear yet if the recent activity indeed marks the final disruption of the progenitor. Regardless of the nature of this event, we use the PTF photometric and spectral observations, as well as Swift-UVOT observations, to constrain the efficiency of the radiated energy relative to the total kinetic energy of the precursor. We find that, using an order-of-magnitude estimate an...

  4. HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells

    Science.gov (United States)

    Yar Saglam, Atiye Seda; Yilmaz, Akin; Onen, Hacer Ilke; Alp, Ebru; Kayhan, Handan; Ekmekci, Abdullah

    2016-01-01

    Histone deacetylases (HDACs) play a major role in the regulation of chromatin structure and gene expression by changing acetylation status of histone and non-histone proteins. MS-275 (entinostat, MS) is a well-known benzamide-based HDACI and Salermide (SAL), a reverse amide compound HDACI, have antiproliferative effects on several human cancer cells. In this study, we aimed to investigate the effects of HDACIs (MS and SAL) alone and/or combined use with EF24 (EF), a novel synthetic curcumin analog, on human pancreatic cancer cell line (BxPC-3). In vitro, BxPC-3 cells were exposed to varying concentrations of MS, SAL with or without EF, and their effects on cell viability, acetylated Histone H3 and H4 levels, cytotoxicity, and cleaved caspase 3 levels, and cell cycle distribution were measured. The viability of BxPC-3 cells decreased significantly after treatment with EF, MS and SAL treatments. MS and SAL treatment increased the acetylation of histone H3 and H4 in a dose dependent manner. MS and SAL alone or combined with EF were increased the number of cells in G1 phase. In addition, treatment with agents significantly decreased the ratio of cell in G2/M phase. There were significant dose-dependent increases at cleaved Caspase 3 levels after MS treatment but not after SAL treatment. Our results showed that HDAC inhibitors (MS and SAL), when combined with EF, may effectively reduce pancreatic cancer cell (BxPC-3) progression and stop the cell cycle at G1 phase. Further molecular analyses are needed to understand the fundamental molecular consequences of HDAC inhibition in pancreas cancer cells. PMID:27330528

  5. Formation of quasicrystals in Zr46.8Ti8.2Cu7.5Ni10Be27.5 bulk glass

    DEFF Research Database (Denmark)

    Wanderka, N.; Macht, M. P.; Siedel, M.;

    2000-01-01

    The formation of the quasicrystalline phase is observed as a first step of crystallization during isothermal annealing of the Zr46.7Ti8.3Cu7.5Ni10Be27.5 bulk glass. The structure of the quasicrystals and the sequence of phase formation have been investigated by x-ray powder diffraction and transm......The formation of the quasicrystalline phase is observed as a first step of crystallization during isothermal annealing of the Zr46.7Ti8.3Cu7.5Ni10Be27.5 bulk glass. The structure of the quasicrystals and the sequence of phase formation have been investigated by x-ray powder diffraction...

  6. Análisis del efecto entalla en la tenacidad aparente y en los micromecanismos de rotura del acero S275JR en condiciones de lower shelf

    OpenAIRE

    Cicero González, Sergio; García Pemán, Tiberio; Madrazo Acebes, Virginia; Ruiz Martínez, Estela

    2014-01-01

    La resistencia a fractura de los materiales es generalmente mayor en condiciones entalladas que en condiciones fisuradas. En otras palabras, cuando el radio de entalla crece se produce igualmente un aumento de la tenacidad aparente a fractura, que es aquella observada en condiciones entalladas. Este artículo presenta un análisis del efecto entalla en el acero S275JR cuando opera a temperaturas pertenecientes al Lower Shelf del material, es decir, aquellas temperaturas en las cuales la fractur...

  7. GCK-MODY diabetes as a protein misfolding disease: the mutation R275C promotes protein misfolding, self-association and cellular degradation.

    Science.gov (United States)

    Negahdar, Maria; Aukrust, Ingvild; Molnes, Janne; Solheim, Marie H; Johansson, Bente B; Sagen, Jørn V; Dahl-Jørgensen, Knut; Kulkarni, Rohit N; Søvik, Oddmund; Flatmark, Torgeir; Njølstad, Pål R; Bjørkhaug, Lise

    2014-01-25

    GCK-MODY, dominantly inherited mild hyperglycemia, is associated with more than 600 mutations in the glucokinase gene. Different molecular mechanisms have been shown to explain GCK-MODY. Here, we report a Pakistani family harboring the glucokinase mutation c.823C>T (p.R275C). The recombinant and in cellulo expressed mutant pancreatic enzyme revealed slightly increased enzyme activity (kcat) and normal affinity for α-D-glucose, and resistance to limited proteolysis by trypsin comparable with wild-type. When stably expressed in HEK293 cells and MIN6 β-cells (at different levels), the mutant protein appeared misfolded and unstable with a propensity to form dimers and aggregates. Its degradation rate was increased, involving the lysosomal and proteasomal quality control systems. On mutation, a hydrogen bond between the R275 side-chain and the carbonyl oxygen of D267 is broken, destabilizing the F260-L271 loop structure and the protein. This promotes the formation of dimers/aggregates and suggests that an increased cellular degradation is the molecular mechanism by which R275C causes GCK-MODY.

  8. Mapping spin-wave dispersions in stripe-ordered La2-xSrxNiO4 ( x=0.275 , 0.333)

    Science.gov (United States)

    Woo, Hyungje; Boothroyd, A. T.; Nakajima, K.; Perring, T. G.; Frost, C. D.; Freeman, P. G.; Prabhakaran, D.; Yamada, K.; Tranquada, J. M.

    2005-08-01

    Using the MAPS spectrometer at the ISIS spallation source, we have measured the magnetic excitations of single-crystal samples of stripe-ordered La2-xSrxNiO4 with x=0.333 and 0.275. The full two-dimensional spin-wave dispersions were obtained using incident energies of 60 and 160 meV. To analyze the excitations, we have evaluated a spin-only Hamiltonian describing diagonal, site-centered stripes in the linear spin-wave approximation. Besides the superexchange energy J within antiferromagnetic domains, we have considered effective exchange couplings J1 and J2 across a charge stripe coupling second-neighbor Ni sites along Ni-O bond directions and along the plaquette diagonal, respectively. From least-squares fits of the model to the measurements on the x=1/3 sample at T=10K , we find that the dispersions are well described by a model using just J and J1 , but not J and J2 . Consistent with an analysis of previous measurements, we find that J is about 90% of the superexchange energy of undoped La2NiO4 and J1/J≈0.5 . The excitations observed for x=0.275 are surprisingly similar to those for x=1/3 , despite the differing magnetic-ordering wave vectors; the main difference is a broadening of the excitations for x=0.275 . For both samples, we find that one spin-wave branch has a gap of ˜20meV , confirming a previous observation for x=1/3 . We discuss the possible origin of this gap.

  9. Pressure effect of glass transition temperature in Zr46.8Ti8.2Cu7.5Ni10Be27.5 bulk metallic glass

    DEFF Research Database (Denmark)

    Jiang, Jianzhong; Roseker, W.; Sikorski, M.;

    2004-01-01

    Pressure effects on glass transition temperature and supercooled liquid region of a Zr46.8Ti8.2Cu7.5Ni10Be27.5 bulk glass have been investigated by performing in situ high-temperature and high-pressure x-ray powder diffraction measurements using synchrotron radiation. The glass transition was det...... range of 0-2.2 GPa. This method opens a possibility to study the pressure effect of glass transition process in glassy systems under high pressures (>1 GPa). (C) 2004 American Institute of Physics....

  10. Fe72.5Ga27.5合金的定向凝固工艺与磁致伸缩性能研究%Directional Solidification and Magnetostricive Properties of Fe72.2Ga27.5 Alloys

    Institute of Scientific and Technical Information of China (English)

    徐立红; 祁焱; 王蕾; 杜兆富; 何峻; 赵栋梁

    2012-01-01

    The influence of different parameters (temperature gradient Gl and crystal growth velocity V) on the Fe72.5Ga27.5 crystal orientation in the process of crystal growth were studied in this paper. The effect of different heat treatments on the magnetostrictive properties of polycrystalline Fe72.5Ga27.5 alloys were studied, which including furnace cooling, air cooling and quenched. Necessary explanations were made by microstructure analysis. The re-sults show that: The magnetostrictive property of the sample is closely related to the temperature gradient and growth rate. There are no obvious microstructure changes in the orientation of polycrystalline samples after the heat treatment The magnetostrictive property of the oriented polycrystalline sample after quenching has improved significantly.%研究了晶体生长过程中的不同参数(温度梯度GL,晶体生长速度V)对Fe72.5Ga27.5合金晶体取向规律的影响.Fe72.5Ga27.5合金经过炉冷、空冷及淬火等热处理后,研究了热处理对<110>取向多晶合金磁致伸缩性能的影响,并通过微观组织分析进行必要的解释.结果表明:样品的性能与温度梯度和生长速度有着密切的关系.取向多晶样品热处理前后组织形貌没有明显变化,淬火后<110>轴向取向多晶FeGa样品的性能明显提高.

  11. Solidification pathways of ternary Cu62.5Fe27.5Sn10 alloy modulated through liquid undercooling and containerless processing

    Science.gov (United States)

    Xia, Z. C.; Wang, W. L.; Wu, Y. H.; Luo, S. B.; Wei, B.

    2016-11-01

    The active control of microstructure evolution is still a challenging factor for the development of advanced immiscible alloys. Here, we make an attempt to modulate the solidification pathways of undercooled Cu62.5Fe27.5Sn10 alloy by glass fluxing and drop tube techniques. Through regulating the liquid undercooling, three types of microstructures, dendrite, dispersive structure and macrosegregation pattern, were formed under the normal gravity condition. Below the first critical undercooling of 15 K, the alloy melt displayed the normal peritectic solidification. At moderate undercoolings above 15 K, the metastable liquid phase separation took place and the solidified microstructure appeared as homogeneously dispersed structure. If undercooling further overtook the second threshold of 107 K, macrosegregation occurred and the bulk alloy separated into an Fe-rich zone and a Cu-rich zone. Under the free fall condition, the alloy droplets with the droplet diameter beyond 805 μm showed the equilibrium peritectic solidification. If the droplet diameter decreased below 805 μm, the metastable liquid phase separation was induced and the microstructural morphology of Cu62.5Fe27.5Sn10 alloy droplet evolved from dendrite into dispersive structure. Furthermore, experimental and simulated results revealed that the temperature gradient had great influence on the size distribution of Fe-rich globules.

  12. 组蛋白去乙酰化酶抑制剂MS-275对创伤性脑损伤大鼠的神经保护作用%Neuroprotective effect of histone deacetylases inhibitor MS-275 following traumatic brain injury in rats

    Institute of Scientific and Technical Information of China (English)

    曹鹏; 宋振全; 于春泳; 冯思哲; 胡国汉; 卢亦成

    2013-01-01

    目的 探讨组蛋白去乙酰化酶(histone deacetylases,HDAC)抑制剂MS-275对大鼠中度创伤性颅脑损伤(traumatic brain injury,TBI)的神经保护作用. 方法 68只SD成年雄性大鼠按随机数字表法分为4组:无损伤对照+安慰剂组(对照组)、脑损伤+安慰剂组(损伤组)、脑损伤+ 15mg/kg MS-275组(治疗Ⅰ组)和脑损伤+45mg/kg MS-275组(治疗Ⅱ组).大鼠侧方液压打击装置诱导形成中度实验性TBI模型.MS-275溶解于二甲基亚砜中,15,45 mg/kg两种浓度的MS-275伤后连续7d(1次/d)腹腔注射大鼠体内,首次给药于伤后30 min完成.伤后记录各组大鼠体重变化,伤后10 ~ 14 d行Morris水迷宫测试评估大鼠空间探索及记忆存储功能.脑组织经提取固定后通过免疫组化及甲酚紫组织染色方法比较不同组别海马CA2 ~3区乙酰化组蛋白H3水平和存活神经细胞数量的差异. 结果 与对照组比较,其余3组伤后前3d体重均显著下降(P<0.05),伤后4~5d体重逐渐增加至伤前基础体重水平,但各组间差异无统计学意义(F=0.149,P>0.05).行为学测试结果显示,与损伤组比较,两治疗组均可明显改善大鼠伤后认知行为表现(P<0.01).组织染色结果显示,两治疗组均可明显增加脑组织乙酰化组蛋白H3水平,与对照组比较差异无统计学意义;伤后14 d两治疗组均表现出脑组织海马CA2 ~3区神经细胞存活数量增加的趋势(P>0.05). 结论 MS-275可显著改善大鼠TBI后急性期乙酰化组蛋白水平及认知行为功能,同时改善TBI后的病理变化,对神经起到一定的保护作用.%Objective To evaluate the neuroprotective benefits of histone deacetylases (HDAC)inhibitor MS-275 in rats with moderate traumatic brain injury (TBI).Methods Sixty-eight adult male SD rats were assigned to sham injury + placebo treatment (control group),TBI + placebo treatment (injury group),TBI + MS-275 (15 mg/kg) treatment (treatment group Ⅰ) and TBI + MS-275 (45

  13. Transmission-electron-microscopy study of charge-stripe order in La1.725Sr0.275NiO4

    Science.gov (United States)

    Li, Jianqi; Zhu, Yimei; Tranquada, J. M.; Yamada, K.; Buttrey, D. J.

    2003-01-01

    We characterize the local structure and correlations of charge stripes in La1.725Sr0.275NiO4 using transmission-electron microscopy. We present direct evidence that the stripe modulation is indeed one-dimensional within each NiO2 plane. Furthermore, we show that individual stripes tend to be either site centered or bond centered, with a bias towards the former. The spacing between stripes often fluctuates about the mean separation, contributing to a certain degree of frustration of the approximate body-centered stacking along the c axis. These results confirm ideas inferred from previous neutron-diffraction measurements on doped nickelates, and demonstrate that charge-stripe order is quite different from the conventional concept of charge-density-wave order.

  14. A novel R275X mutation of the SLC25A15 gene in a Japanese patient with the HHH syndrome.

    Science.gov (United States)

    Torisu, Hiroyuki; Kira, Ryutaro; Kanazawa, Naomi; Takemoto, Megumi; Sanefuji, Masafumi; Sakai, Yasunari; Tsujino, Seiichi; Hara, Toshiro

    2006-06-01

    The hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome (MIM 238970) is an autosomal recessive metabolic disorder caused by a deficiency of the mitochondrial ornithine transporter, one of the urea cycle components. Mutations in the SLC25A15 gene have been coupled to the HHH syndrome. We describe a Japanese female patient with the HHH syndrome due to a novel homozygous R275X SLC25A15 mutation and male sibling who presumably carried the same mutation. He exhibited slowly progressive deterioration with seizures, a gait disturbance due to polyneuropathy, episodic confusion, and died of acute encephalopathy at 34 years of age while the proband exhibited moderate mental retardation, seizures, mild spastic paraplegia, and deafness without neurological deterioration for more than 20 years. The clinical features of previously documented patients with the homozygous SLC25A15 mutation demonstrated that genotype did not simply correlate with clinical severity. The phenotypic variability might depend on other factors, such as dietary and other genetic ones.

  15. 275例自身免疫性疾病患者ANA与ENA自身抗体的检测分析

    Institute of Scientific and Technical Information of China (English)

    张凤杰

    2012-01-01

    目的 研究抗核抗体(ANA)、抗可提取性核抗原抗体(ENA)自身抗体在自身免疫性疾病患者中的阳性情况及诊断价值.方法 选择临床275例确诊自身免疫性疾病患者为观察组,以87例正常体检人员为对照组,采用胶体金法检测两组ANA、ENA自身抗体.结果 观察组与对照组ANA、ENA阳性率经卡方检验比较分析x2分别为64.39、27.2,P值均<0.001,差异有统计学意义;ANA阳性率在SLE、SS、PSS比较高,分别为89.4%、72.2%、75.0%;ENA阳性率在SLE、PSS比较高,分别为57.6%、45.8%;在275例自身免疫性疾病患者中,女性与男性的ANA、ENA阳性率经卡方检验比较分析x2分别为14.75、4.21,P值均<0.05,差异有统计学意义.结论 ANA、ENA检测对自身免疫性疾病的早期诊断和鉴别其有重要的临床意义.

  16. I223R mutation in influenza A(H1N1pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y.

    Directory of Open Access Journals (Sweden)

    Jérome LeGoff

    Full Text Available BACKGROUND: Resistance of pandemic A(H1N12009 (H1N1pdm09 virus to neuraminidase inhibitors (NAIs has remained limited. A new mutation I223R in the neuraminidase (NA of H1N1pdm09 virus has been reported along with H275Y in immunocompromised patients. The aim of this study was to determine the impact of I223R on oseltamivir and zanamivir susceptibility. METHODS: The NA enzymatic characteristics and susceptibility to NAIs of viruses harbouring the mutations I223R and H275Y alone or in combination were analyzed on viruses produced by reverse genetics and on clinical isolates collected from an immunocompromised patient with sustained influenza H1N1pdm09 virus shedding and treated by oseltamivir (days 0-15 and zanamivir (days 15-25 and 70-80. RESULTS: Compared with the wild type, the NA of recombinant viruses and clinical isolates with H275Y or I223R mutations had about two-fold reduced affinity for the substrate. The H275Y and I223R isolates showed decreased susceptibility to oseltamivir (246-fold and oseltamivir and zanamivir (8.9- and 4.9-fold, respectively. Reverse genetics assays confirmed these results and further showed that the double mutation H275Y and I223R conferred enhanced levels of resistance to oseltamivir and zanamivir (6195- and 15.2-fold. In the patient, six days after initiation of oseltamivir therapy, the mutation H275Y conferring oseltamivir resistance and the I223R mutation were detected in the NA. Mutations were detected concomitantly from day 6-69 but molecular cloning did not show any variant harbouring both mutations. Despite cessation of NAI treatment, the mutation I223R persisted along with additional mutations in the NA and the hemagglutinin. CONCLUSIONS: Reduced susceptibility to both oseltamivir and zanamivir was conferred by the I223R mutation which potentiated resistance to both NAIs when associated with the H275Y mutation in the NA. Concomitant emergence of the I223R and H275Y mutations under oseltamivir treatment

  17. Reverse-transcription polymerase chain reaction/pyrosequencing to characterize neuraminidase H275 residue of influenza A 2009 H1N1 virus for rapid and specific detection of the viral oseltamivir resistance marker in a clinical laboratory.

    Science.gov (United States)

    Bao, Jian R; Huard, Thomas K; Piscitelli, Arelis E; Tummala, Praveena R; Aleemi, Virginia E; Coon, Stephanie L; Master, Ronald N; Lewinski, Michael A; Clark, Richard B

    2011-12-01

    Pandemic 2009 H1N1 is normally susceptible to oseltamivir, but variants harboring the H275Y (CAC → TAC) mutation exhibit resistance. We describe the use of a combined reverse-transcription polymerase chain reaction (RT-PCR)/pyrosequencing approach to identify the H275 residue. A total of 223 specimens were tested with this method: 216 randomly selected clinical specimens positive for 2009 H1N1 and 7 cell-culture supernatants from the Centers for Disease Control and Prevention (CDC; 4 resistant, 3 susceptible 2009 H1N1 strains). The assay detected H275Y in 1 clinical respiratory sample (0.5%) and all 4 oseltamivir-resistant strains from the CDC; the remaining 215 clinical and 3 susceptible CDC specimens were wild-type. Sanger sequencing confirmed the results for 50 of 50 selected isolates. The RT-PCR/pyrosequencing method was highly specific, producing no amplicons or valid sequences from samples containing non-H1N1 viruses or bacteria. Our findings suggest that this method provides a rapid tool for H275Y detection, with high sensitivity and potential benefit for patient care.

  18. Persistence of pandemic influenza H1N1 virus in young patients after oseltamivir therapy in the 2009-2010 season: a comparison with seasonal H1N1 with or without H275Y mutation.

    Science.gov (United States)

    Kawai, Naoki; Ikematsu, Hideyuki; Iwaki, Norio; Kondou, Kunio; Hirotsu, Nobuo; Kawashima, Takashi; Maeda, Tetsunari; Tanaka, Osame; Doniwa, Ken-ichi; Iwakuni, Osamu; Egashira, Keisuke; Yamaji, Kouzaburo; Kashiwagi, Seizaburo

    2012-04-01

    Comparison of the viral persistence of pandemic H1N1 (H1N1pdm) and seasonal H1N1 with or without H275Y mutation after oseltamivir therapy has not been adequately done. Virus was isolated before and on days 4-6 from the start of oseltamivir treatment for 158 cases of seasonal (2007-2008 and 2008-2009 seasons) or pandemic (2009-2010 season) H1N1 influenza. Sequence analysis was done for each season and NA inhibition assay (IC(50)) was done in the 2009-2010 season. H275Y mutation before therapy was 0% in the 2007-2008 and 2009-2010 seasons, but 100% in the 2008-2009 season. Fever and other symptoms were noticeably prolonged after oseltamivir therapy for children with H275Y mutated seasonal H1N1 (2008-2009 season), but not in patients with seasonal H1N1 without mutation (2007-2008) or H1N1pdm (2009-2010). The viral persistence rate was significantly higher for patients 15 years or younger than for those 16 years and older with H275Y mutated seasonal H1N1 (46.2% and 10.5%, respectively) or with H1N1pdm (43.3% and 11.5%, respectively). The H275Y mutation emerged after oseltamivir treatment in 2.4% (2/82) of all patients with H1N1pdm. In two children, the H275Y mutation emerged after therapy and the IC(50) increased more than 200 fold; however, the prolongation of fever was not so prominent. In conclusion, oseltamivir was effective for fever and other clinical symptoms; however, the virus persisted longer than expected after treatment in H1N1pdm influenza-infected children in the 2009-2010 season, similar to seasonal H1N1 with H275Y mutation in the 2008-2009 season.

  19. Exploiting MISR products at the full spatial resolution (275m) to document changes in land properties in and around the Kruger National Park, South Africa

    Science.gov (United States)

    Verstraete, M. M.; Hunt, L. A.; Pinty, B.; Clerici, M.; Scholes, R. J.

    2009-12-01

    The MISR instrument on NASA's Terra platform has been acquiring data globally and continuously for almost 10 years. A wide range of atmospheric and land products are operationally generated at the LaRC ASDC, at spatial resolutions of 1.1 km or coarser. Yet, the intrinsic spatial resolution of that sensor is 275m and 12 out of the 36 spectro-directional data channels are transmitted to the ground segment at that resolution. Recent algorithmic developments have permitted us to reconstruct reasonable estimates of the other 24 channels and to account for atmospheric effects at the full original spatial resolution. Spectro-directional reflectances have been processed to characterize the anisotropy of observed land surfaces and then optimally estimate various geophysical properties of the environment such as the fluxes of radiation in and out of plant canopies, the albedo, FAPAR, etc. These detailed products allow us to investigate ecological and environmental changes in much greater spatial and thematic detail than was previously possible. The paper outlines the various methodological steps implemented and exhibits concrete results for a region of moderate size (280 by 380 km) in South Africa. Practical downstream applications of this approach include monitoring desertification and biomass burning, documenting urbanization or characterizing the phenology of vegetation.

  20. 纤维蛋白原γ链Arg275His突变所致的遗传性异常纤维蛋白原血症家系分析%Analysis of a family with congenital dysfibrinogenemia caused by an Arg275His mutation in the gamma chain of fibrinogen

    Institute of Scientific and Technical Information of China (English)

    闫婕; 邓东红; 邓雪连; 罗美玲; 程鹏; 廖林; 林发全

    2016-01-01

    Objective To explore the clinical phenotype of a family affected with congenital dysfibrinogenemia and potential mutations underlying the disease.Methods Coagulation testing and hepatorenal function testing were conducted on 18 individuals fromthree generations.Plasma fibrinogen was extracted and analyzed with SDS-PAGE electrophoresis.All of the exons and flanking sequences of fibrinogen FGA,FGB,FGG genes were analyzed by PCR,and the products were subjected to Sanger sequencing.Results Hepatorenal function,prothrombin time and activated partial thromboplastin time of the proband were all normal.However,his thrombin time was significantly prolonged.Fibrinogen activity was decreased,while the concentration of antigen was in the normal range.The results of his mother,brother,and nephew were similar.DNA sequencing has confirmed that the proband,his mother,brother,and nephew have all carried a g.5877G> A mutation in the exon 8 of the FGG gene,which resultedin replacement of arginine (Arg) by histidine (His) at position 275.Conclusion The Arg275His mutation of the fibrinogen γ chain probably underlies the pathogenesis of congenital dysfibrinogenemia in this family.%目的 对1个遗传性异常纤维蛋白原血症家系进行临床表型和基因型研究,了解其分子遗传学发病机制.方法 抽取家系18名成员外周血,进行凝血指标检测;提取血浆纤维蛋白原,进行SDS-PAGE电泳;PCR扩增纤维蛋白原FGA、FGB、FGG基因所有外显子以及侧翼序列.PCR扩增产物进行测序,确定突变位点.结果 先证者肝肾功能、凝血酶原时间与活化部分凝血活酶时间均正常,但凝血酶时间显著延长.纤维蛋白原活性明显降低,而抗原浓度在正常范围,先证者母亲、弟弟及侄子的表型检测结果与其相似.基因测序结果显示,先证者及其母亲、弟弟及侄子FGG基因第8外显子发生了g.5877G>A杂合突变,导致275位的精氨酸(Arg)被组氨酸(His)取代.FGG基因第8

  1. Wide Variety of Experiments Using a Cryogen-Free 27.5 T Hybrid Magnet and a Cryogen-Free 18.1 T Superconducting Magnet

    Science.gov (United States)

    Watanabe, K.; Awaji, S.; Oguro, H.

    2013-03-01

    A cryogen-free hybrid magnet without liquid helium for operation, generating 27.5 T in a 32 mm room temperature bore of an 8 MW water-cooled resistive insert magnet in an 8.5 T background field of a cryogen-free superconducting outsert magnet, is being operated for basic research at low temperatures down to 17 mK in combination with a dilution refrigerator. In addition, we are developing functional materials using a differential thermal analysis DTA at high temperatures up to 1473 K in high fields up to 27 T. This cryogen-free hybrid magnet will be upgraded to generate 29 T by improving the outer superconducting magnet. A cryogen-free 18.1 T superconducting magnet with a 52 mm room temperature experimental bore, consisting of a Bi2Sr2Ca2Cu3O10 (Bi2223) insert coil, has been developed using a GM-JT cryocooler. Recently, bronze-tape-laminated Bi2223 has revealed excellent irreversible stress tolerance of 250 MPa at 77 K. In addition, the critical current properties for recent Bi2223 tapes are largely improved from 200 to 400 A/cm-width at 77 K in a self-field. Therefore, the stainless steel reinforcement tape incorporated for the previous Bi2223 insert coil is no longer needed for a new Bi2223 one. A new Bi2223 insert coil with almost the same size as the existing insert coil can generate two times higher fields at the elevated operation current from 162 to 191 A. An upgraded cryogen-free superconducting magnet can offer a long-term experiment at the constant magnetic field of 20 T for an in-field heat-treatment investigation.

  2. Study of {Lambda}{sup 0} Polarization in Four Different Exclusive pp Reactions at 27.5 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Felix, J.; Avilez, C.; Moreno, G. [Universidad de Guanajuato, Leon, Guanajuato (Mexico); Hartouni, E.P.; Jensen, D.A.; Kreisler, M.N.; Uribe, J.; Wang, M.H. [University of Massachusetts, Amherst, Massachusetts 01003 (United States); Christian, D.C.; Gutierrez, G.; Holmes, S.D.; Wehmann, A. [Fermilab, Batavia, Illinois 60510 (United States); Church, M.D.; Gottschalk, E.E.; Knapp, B.C.; Stern, B.J.; Wiencke, L.R. [Columbia University, Nevis Laboratories, Irvington, New York 10533 (United States); Forbush, M.; Huson, F.R.; White, J.T. [Department of Physics, Texas AM University, College Station, Texas 77843 (United States)

    1999-06-01

    We have measured the x{sub F} and P{sub T} dependence of the polarization of {Lambda}{sup 0} hyperons produced in exclusive final states pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +} {pi}{sup {minus}} , pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +} {pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}} , pp{r_arrow}p{Lambda}{sup 0}K{sup + }{pi}{sup +}{pi}{sup {minus}}{pi}{sup +} {pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}} , and pp{r_arrow}p{Lambda}{sup 0}K{sup +}{pi}{sup +} {pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus} } at 27.5thinspthinspGeV/c . We present an empirical parametrization for {Lambda}{sup 0} polarization as a function of x{sub F} and P{sub T} : P=({minus}0.443{plus_minus}0.03 7)x{sub F}P{sub T} for {minus}1{le}x{sub F}{le}1 and 0{le}P{sub T}{le}1.8 GeV/ c . This parametrization is independent of the final state and provides a good description of the data. We note that the mechanism responsible for {Lambda}{sup 0} polarization appears to be independent of the production mechanism. {copyright} {ital 1999} {ital The American Physical Society}

  3. Speed-of-Sound Measurements in (Argon + Carbon Dioxide) over the Temperature Range from (275 to 500) K at Pressures up to 8 MPa.

    Science.gov (United States)

    Wegge, Robin; McLinden, Mark O; Perkins, Richard A; Richter, Markus; Span, Roland

    2016-08-01

    The speed of sound of two (argon + carbon dioxide) mixtures was measured over the temperature range from (275 to 500) K with pressures up to 8 MPa utilizing a spherical acoustic resonator. The compositions of the gravimetrically prepared mixtures were (0.50104 and 0.74981) mole fraction carbon dioxide. The vibrational relaxation of pure carbon dioxide led to high sound absorption, which significantly impeded the sound-speed measurements on carbon dioxide and its mixtures; pre-condensation may have also affected the results for some measurements near the dew line. Thus, in contrast to the standard operating procedure for speed-of-sound measurements with a spherical resonator, non-radial resonances at lower frequencies were taken into account. Still, the data show a comparatively large scatter, and the usual repeatability of this general type of instrument could not be realized with the present measurements. Nonetheless, the average relative combined expanded uncertainty (k = 2) in speed of sound ranged from (0.042 to 0.056)% for both mixtures, with individual state-point uncertainties increasing to 0.1%. These uncertainties are adequate for our intended purpose of evaluating thermodynamic models. The results are compared to a Helmholtz energy equation of state for carbon capture and storage applications; relative deviations of (-0.64 to 0.08)% for the (0.49896 argon + 0.50104 carbon dioxide) mixture, and of (-1.52 to 0.77)% for the (0.25019 argon + 0.74981 carbon dioxide) mixture were observed.

  4. 纤维蛋白原γ链Arg275His突变所致异常纤维蛋白原的功能研究%Functional study of abnormal fibrinogen caused by Arg275His mutation in fibrinogen γchain

    Institute of Scientific and Technical Information of China (English)

    周景艺; 王学锋; 丁秋兰; 许冠群; 张利伟; 戴菁; 陆晔玲; 奚晓东; 王鸿利

    2013-01-01

    目的 对两个遗传性异常纤维蛋白原血症家系的突变纤维蛋白原(Fg)进行功能研究.方法 常规筛查凝血功能;Fg抗原和活性分别用免疫比浊法和Clauss法测定;抽提DNA,对Fg 3个基因(FGA、FGB和FGG)以及抗凝血酶基因(AT3)所有外显子及侧翼序列进行PCR扩增、测序及分析;采用常规血栓弹力图(TEG)和功能性FgTEG检查对家系B先证者及其父亲进行凝血功能的综合评价及血浆功能性Fg评估;应用Western blot检测血浆Fg肽链分子量;采用Fg动态聚集曲线和纤维蛋白溶解曲线实验检测血浆Fg的功能.结果 2例先证者凝血酶原时间(TT)和爬虫酶凝固时间(RT)明显延长,Fg活性仅为0.5 g/L和0.6 g/L,但其抗原均正常,分别为2.32 g/L和2.66 g/L.两个家系先证者均存在γ链Arg275His杂合突变,家系B先证者的祖父和姑母同时检出AT3 g.5876T>C(Ser116Pro)杂合突变.家系B先证者及其父亲TEG检测结果中α值分别接近和低于正常参考值范围下限,但最大波幅(MA值)均为正常;在功能性Fg TEG检测中,MA值明显偏低.Fg动态聚集曲线中先证者和家系患者的起跳时间明显延长、峰值明显降低.纤维蛋白溶解曲线中多数患者的纤维蛋白在特定时间内不能被纤溶酶原完全溶解.结论 首次发现遗传性异常纤维蛋白原血症合并AT缺陷的患者.γ链Arg275 His突变使Fg在纤维蛋白单体聚合以及纤维蛋白溶解方面出现异常.联合应用常规TEG和功能性TEG检测,可以更好地评估异常纤维蛋白原血症患者Fg的功能.%Objective To investigate the function of abnormal fibrinogen in two inherited dysfibrinogenemia pedigrees.Methods Routine coagulation tests were conducted in the probands and related family members.The antigen and activity levels of fibrinogen were detected by immunoturbidimetry assay and clauss assay,respectively.All the exons and exon-intron boundaries of the three fibrinogen genes and antithrombin gene (AT3

  5. Inherited dysfibrinogenemia caused by Arg275His in the γ chain of fibrinogen%一个纤维蛋白原γ链Arg275His突变导致的遗传性异常纤维蛋白原血症家系

    Institute of Scientific and Technical Information of China (English)

    方怡; 王鸿利; 王学锋; 傅启华; 武文漫; 丁秋兰; 戴菁; 周荣富; 王文斌; 谢爽

    2005-01-01

    目的对一个遗传性异常纤维蛋白原血症家系进行表型和基因型分析.方法采集家系3代5人外周血,吸取上层血浆用血凝仪检测活化部分凝血酶原时间、凝血酶原时间、凝血酶时间、蛋白C活性、蛋白S活性和抗凝血酶活性,纤维蛋白原活性和抗原分别用Clauss法和免疫比浊法进行检测.以常规酚-氯仿法抽提家系所有成员外周血基因组DNA,PCR扩增纤维蛋白原基因FGA、FGB和FGG所有外显子及其侧翼序列,PCR产物纯化后直接测序以检测基因突变.结果先证者活化部分凝血酶原时间、凝血酶原时间正常,凝血酶时间超出正常上限值2倍以上,纤维蛋白原活性明显下降,抗原也低于正常范围,且活性显著低于抗原;其母表型检测结果与之相似.基因分析显示先证者呈纤维蛋白原FGG基因第8外显子g.5678 G>A杂合碱基置换,导致Arg275His错义突变,该突变来源于母系.结论纤维蛋白原γ链Arg275His杂合错义突变是引起该家系异常纤维蛋白原血症的原因.

  6. Thirty-eight-year follow-up of two sibling Lipoid Congenital Adrenal Hyperplasia patients due to homozygous Steroidogenic Acute Regulatory (STARD1 protein Mutation. Molecular structure and modeling of the STARD1 L275P mutation.

    Directory of Open Access Journals (Sweden)

    Jean-Guy Lehoux

    2016-11-01

    Full Text Available Objective: Review the impact of StAR (STARD1 mutations on steroidogenesis and fertility in LCAH patients. Examine the endocrine mechanisms underlying the pathology of the disorder and the appropriate therapy for promoting fertility and pregnancies.Design: Published data in the literature and a detailed 38-year follow-up of two sibling LCAH patients. Molecular structure and modeling of the STARD1 L275P mutation.Setting : University hospital.Patients: Patient A (46,XY female phenotype and patient B (46,XX female with LCAH bearing the L275P mutation in STARD1.Interventions : Since early-age diagnosis, both patients underwent corticoid replacement therapy. Patient A received estrogen therapy at pubertal age. Clomiphene therapy was given to Patient B to induce ovulation. Pregnancies were protected with progesterone administration.Main Outcome Measures : Clinical and molecular assessment of adrenal and gonadal functions.Results: Both patients have classic manifestations of corticosteroid deficiency observed in LCAH. Time of onset and severity were different. Patient A developed into a female phenotype due to early and severe damage of Leydig cells. Patient B started a progressive pubertal development, menarche and regular non-ovulatory cycle. She was able to have successful pregnancies.Conclusions: Understanding the molecular structure and function of STARD1 in all steroidogenic tissues is the key for comprehending the heterogeneous clinical manifestations of LCAH, and the development of an appropriate strategy for the induction of ovulation and protecting pregnancies in this disease.

  7. Correlation between ferromagnetism and the concentration of interfacial defects in multiferroic Bi7Fe2.75Co0.25Ti3O21 studied by positron annihilation

    Science.gov (United States)

    Ge, W. N.; Li, X. N.; Xu, J. P.; Huang, S. J.; Liu, J. D.; Zhu, Z.; Fu, Z. P.; Lu, Y. L.; Ye, B. J.

    2017-03-01

    This paper investigated the effect of the annealing temperature on the interfacial defects and the magnetization of a single-phase multiferroic Bi7Fe2.75Co0.25Ti3O21. With the increase of annealing temperature, the average thickness of the nonaplates increased from 80 to 180 nm. But the magnetic property measurement shows that the saturation magnetization gradually decreases with the increase of the annealing temperature correspondingly. Positron annihilation measurements reveal that the interfacial defects disappear obviously when the annealing temperature increased, which is found to agree well with the variation of saturation magnetization. The results suggest that with the higher concentration of interfacial defects may bring about higher saturation magnetization for the Aurivillius phase material, opening a window to improve the magnetic performance through controlling the concentration of interfacial defects.

  8. Rapid detection of the H275Y oseltamivir resistance mutation in influenza A/H1N1 2009 by single base pair RT-PCR and high-resolution melting.

    Directory of Open Access Journals (Sweden)

    Steven Y C Tong

    Full Text Available INTRODUCTION: We aimed to design a real-time reverse-transcriptase-PCR (rRT-PCR, high-resolution melting (HRM assay to detect the H275Y mutation that confers oseltamivir resistance in influenza A/H1N1 2009 viruses. FINDINGS: A novel strategy of amplifying a single base pair, the relevant SNP at position 823 of the neuraminidase gene, was chosen to maintain specificity of the assay. Wildtype and mutant virus were differentiated when using known reference samples of cell-cultured virus. However, when dilutions of these reference samples were assayed, amplification of non-specific primer-dimer was evident and affected the overall melting temperature (T(m of the amplified products. Due to primer-dimer appearance at >30 cycles we found that if the cycle threshold (C(T for a dilution was >30, the HRM assay did not consistently discriminate mutant from wildtype. Where the C(T was 32.98 would have an H275Y assay C(T>30. Analysis of the TaqMan C(T values for 609 consecutive clinical samples predicted that 207 (34% of the samples would result in an HRM assay C(T>30 and therefore not be amenable to the HRM assay. CONCLUSIONS: The use of single base pair PCR and HRM can be useful for specifically interrogating SNPs. When applied to H1N1 09, the constraints this placed on primer design resulted in amplification of primer-dimer products. The impact primer-dimer had on HRM curves was adjusted for by plotting T(m against C(T. Although less sensitive than TaqMan assays, the HRM assay can rapidly, and at low cost, screen samples with moderate viral concentrations.

  9. UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients.

    Science.gov (United States)

    van Schaik, R H N; van Agteren, M; de Fijter, J W; Hartmann, A; Schmidt, J; Budde, K; Kuypers, D; Le Meur, Y; van der Werf, M; Mamelok, R; van Gelder, T

    2009-09-01

    Mycophenolate mofetil (MMF) is an immunosuppressive drug commonly used in the context of kidney transplantation. Exposure to the active metabolite mycophenolic acid (MPA) is associated with risk of allograft rejection. MPA pharmacokinetics varies between individuals, the potential cause being the presence of genetic polymorphisms in key enzymes. We genotyped 338 kidney transplant patients for UGT1A8, UGT1A9, UGT2B7, and MRP2 polymorphisms and recorded MPA exposure and biopsy-proven acute rejections (BPARs) during a 1-year follow-up. Tacrolimus-treated patients who were UGT1A9 -275T>A and/or -2152C>T carriers displayed a 20% lower MPA area under the concentration-time curve from 0 to 12 h (AUC(0-12)) (P = 0.012). UGT1A9*3 carriers displayed a 49% higher MPA AUC(0-12) when treated with tacrolimus and a 54% higher MPA AUC(0-12) when treated with cyclosporine (P A and/or -2152C>T polymorphism significantly predicted acute rejection in fixed-dose (FD) MMF-treated patients receiving tacrolimus (odds ratio 13.3, 95% confidence interval 1.1-162.3; P A and/or -2152C>T genotyping may identify patients at risk of MPA underexposure and acute rejection when receiving treatment with MMF and tacrolimus.

  10. 49 CFR 27.5 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... job in question, but the term does not include any individual who is an alcoholic or drug abuser whose current use of alcohol or drugs prevents such person from performing the duties of the job in question or...; cancer; heart disease; mental retardation; emotional illness; drug addiction; and alcoholism. (b)...

  11. BDML Metadata: 275 [SSBD[Archive

    Lifescience Database Archive (English)

    Full Text Available Ce_KK_P002 BDML file for quantitative information about nuclear division dynamics o...f wild-type embryo quantitative information about nuclear division dynamics in wild-type embryo C. elegans nuclear division dynamic

  12. 48 CFR 211.275-2 - Policy.

    Science.gov (United States)

    2010-10-01

    ... that— (1) Contain items in any of the following classes of supply, as defined in DoD 4140.1-R, DoD Supply Chain Materiel Management Regulation, AP1.1.11: (i) Subclass of Class I—Packaged operational... administrative and housekeeping supplies and equipment. (iii) Class IIIP—Packaged petroleum, lubricants,...

  13. 7 CFR 275.15 - Data management.

    Science.gov (United States)

    2010-01-01

    ...; (2) Identify causal factors and their relationships; (3) Identify magnitude of each deficiency, where... available to make a determination of the actual causal factor(s), magnitude, or geographic extent necessary... problems arise from the causal factors which contributed to the occurrence of previously...

  14. CONDIÇÕES HIGIÊNICAS DE FATIADORES DE FRIOS AVALIADAS POR ATP-BIOLUMINESCÊNCIA E CONTAGEM MICROBIANA: SUGESTÃO DE HIGIENIZAÇÃO CONFORME RDC 275 DA ANVISA

    Directory of Open Access Journals (Sweden)

    A. C. S. PIRES

    2009-01-01

    Full Text Available

    As superfícies de fatiadores de frios de sete estabelecimentos comerciais foram consideradas em condições higiênicas insatisfatórias tanto pela análise microbiológica convencional quanto pela técnica do ATP-bioluminescência, de acordo com as recomendações propostas pelas entidades científicas e pesquisas relacionadas, uma vez que não existem padrões estabelecidos pela legislação. As contagens microbianas alcançaram valores elevados, atingindo médias de 3,87 log UFC.cm-2, 1,89 log UFC.cm-2 e 0,86 log UFC.cm-2 , para mesófilos aeróbios, coliformes totais e Staphylococcus coagulase positiva, respectivamente. As contagens de fungos filamentosos e leveduras variaram de 1,58 a 3,88 log UFC.cm-2 e a maioria das contagens de Staphylococcus spp. variou de 2,88 a 3,80 log UFC.cm-2. Constatou-se uma elevada contagem de Staphylococcus spp., que pode ser originária de manipuladores com hábitos higiênicos inadequados, ou dos próprios alimentos fatiados, particularmente no caso de queijos. Uma sugestão de procedimento operacional padronizado (POP para os fatiadores com base na RDC 275/2002 da ANVISA foi disponibilizada aos responsáveis pela higienização dos estabelecimentos comerciais. No POP, foram enfatizados os produtos químicos e as ajudas de limpeza; freqüência e descrição completa do procedimento que inclui concentração, pH, tempo e temperatura de contato. Além do monitoramento do procedimento, medidas de correção e riscos de uma higienização incorreta foram apontados.

  15. This Letter is a Non-Technical Annual Report of Activities on Project 2007-275-00, Impact of American Shad for the Period February 1, 2008 through January 31, 2009.

    Energy Technology Data Exchange (ETDEWEB)

    Parsley, Michael J.

    2009-01-30

    This letter is a non-technical annual report of activities on Project 2007-275-00, Impact of American Shad for the period February 1, 2008 through January 31, 2009. A non-technical report is appropriate at this time since data collection is ongoing and results are preliminary. This report is intended to highlight accomplishments during this performance period. Progress on administrative work elements in the statement of work has been captured in the periodic status reports provided through Pisces. During this performance period the USGS accomplished the following tasks: (1) Co-chaired a symposium on American shad in the Columbia Basin at the annual meeting of the Western Division, American Fisheries Society. The USGS gave four presentations from work done during this project. Abstracts of the presentations were attached to the 2007 progress report. (2) Continued parameterization of a bioenergetics model for juvenile American shad. We performed a literature review to determine the applicability of the existing adult salmon bioenergetics parameters to juvenile fall Chinook salmon in support of our modeling investigation of diet overlap between juvenile American shad and fall Chinook salmon. We formulated testable hypotheses to investigate using bioenergetics models and conceptually developed model simulations. Held an in-house workshop to obtain feedback on the physiological parameters we selected for the American shad bioenergetics model and to solicit feedback on our modeling approach to address research questions. (3) Received a Section 10 ESA sampling permit based on the application submitted in the 2007 contract period. With the ESA permit in hand, we obtained scientific collection permits from the states of Washington and Oregon that allowed us to use a variety of fisheries sampling techniques to capture juvenile and adult American shad. (4) Conducted field sampling to meet project objectives. Gillnetting efforts to capture adult American shad near Astoria were

  16. Study of {Lambda}{sup 0} polarization in {ital pp}{r_arrow}{ital p}{Lambda}{sup 0}{ital K}{sup +}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}} at 27.5 GeV

    Energy Technology Data Exchange (ETDEWEB)

    Felix, J.; Avilez, C.; Moreno, G. [Instituto de Fisica, Universidad de Guanajuato, Leon, Guanajuato 37000 (Mexico); Hartouni, E.P.; Jensen, D.A.; Kreisler, M.N.; Uribe, J. [Department of Physics and Astronomy, University of Massachusetts, Amherst, Massachusetts 01003 (United States); Christian, D.C.; Gutierrez, G.; Holmes, S.D.; Wehmann, A. [Fermilab, Batavia, Illinois 60510 (United States); Church, M.D.; Gottschalk, E.E.; Knapp, B.C.; Stern, B.J.; Wiencke, L.R. [Nevis Laboratories, Columbia University, Irvington, New York 10533 (United States); Forbush, M.; Huson, F.R.; White, J.T. [Department of Physics, Texas A& M University, College Station, Texas 77843 (United States)

    1996-01-01

    We measured the polarization of 51195 {Lambda}{sup 0}{close_quote}s produced in the specific reaction {ital pp}{r_arrow}{ital p}{Lambda}{sup 0}{ital K}{sup +}{pi}{sup +}{pi}{sup {minus}}{pi}{sup +}{pi}{sup {minus}} with 27.5GeV/{ital c} protons incident on a liquid hydrogen target. Because the reaction was measured completely, the polarization was studied versus the following: {ital x}{sub {ital F}}({minus}1to+1), {Lambda}{sup 0} transverse momentum (0 to 1.32GeV/{ital c}), correlations with the momentum vectors of the other particles in the reaction, and the invariant mass of combinations of particles in the final state. The dependence of the polarization on these variables does not always agree with theoretical expectations. {copyright} {ital 1995 The American Physical Society.}

  17. 1935 15' Quad #275 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  18. Dicty_cDB: VFA275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available lkiylekqqkevfhqc*ldyqiifsheetgighdsdffqlii qscyavkkypnidkniltspigwiglntikmignekcwnksssnqlniyslnsevssiks sfsf...rfirfttskfk*ifkfn c**i*l*fn*eirirninfpkirfhfkfyqgkr****ww*ky*yfreypneife*nfrtl in*tikd--- ---iliiyqvvixkvk*l

  19. 40 CFR 98.275 - Procedures for estimating missing data.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Procedures for estimating missing data... for estimating missing data. A complete record of all measured parameters used in the GHG emissions... substitute data value for the missing parameter shall be used in the calculations, according to...

  20. Dicty_cDB: SSE275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CSM-cDNA Score E Sequences producing significant alignments: (bits) Value VHP524 (VHP524Q) /CSM/VH/VHP5-A/V...ignificant alignments: (bits) Value N AC137757 |AC137757.1 Mus musculus chromosome UNK clone RP23-287N15, WO...vs Protein Score E Sequences producing significant alignments: (bits) Value EU016579_19( EU016579 |pid:none)

  1. 50 CFR 216.275 - Requirements for monitoring and reporting.

    Science.gov (United States)

    2010-10-01

    ...—indication of whale/dolphin/pinniped) (C) Number of individuals (D) Calves observed (y/n) (E) Initial...) a brief annual progress update on the status of the development of an effective and unclassified...) Species (if not possible, indicate whale, dolphin or pinniped) (C) Number of individuals (D)...

  2. Nuclear Technology. Course 27: Metrology. Module 27-5, Tolerancing.

    Science.gov (United States)

    Selleck, Ben; Espy, John

    This fifth in a series of eight modules for a course titled Metrology describes the application of the American National Standard (ANSI Y14.5-1973) for dimensioning and tolerancing and gives guidance on interpreting form and location controls consistent with the national standard. The module follows a typical format that includes the following…

  3. 40 CFR 1065.275 - N2O measurement devices.

    Science.gov (United States)

    2010-07-01

    ... infra-red (NDIR) analyzer. You may use an NDIR analyzer that has compensation algorithms that are... for any compensation algorithm is 0.0% (that is, no bias high and no bias low), regardless of the... has compensation algorithms that are functions of other gaseous measurements and the engine's known...

  4. 7 CFR 275.12 - Review of active cases.

    Science.gov (United States)

    2010-01-01

    ... quality control, and that a personal face-to-face interview will be conducted in the future. The method of... eligibility; an overdue subsequent certification; no current application on file; insufficient documentation... that a review is conducted of a household which is receiving restored or retroactive benefits for...

  5. Worldwide Report, Telecommunications Policy, Research and Development, No. 275

    Science.gov (United States)

    2007-11-02

    Connections To Be Provided in Sind (DAWN, 17 May 83) 13 Briefs Reduction in Telex Fee 14 WEST EUROPE FEDERAL REPUBLIC OF GERMANY Broadcasting...Martinsen; AFTENPOSTEN, 4 May 83) 42 Firm Introduces World’s First Automated ’Super Telex ’ (Rolf L. Larsen; AFTENPOSTEN, 6 May 83) .......... ... 44...subsidiary at will and transfer data as required, reducing costs previously incurred through Telex and FAX services. [Perth THE WEST AUSTRALIAN in English 6

  6. Dicty_cDB: CHP275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Salivary Gland 4th instar 3rd period (spinning cocoon) Rhynchosciara americana cDNA, mRNA sequence. 34 3e-0...ence. 48 7e-05 17 CK808739 |CK808739.1 Rasgsc1529 Salivary Gland 4th instar 3rd period (spinning...808037 |CK808037.1 Rasgsc0316 Salivary Gland 4th instar 3rd period (spinning cocoon) Rhynchosciara americana

  7. 36 CFR 223.275 - Establishment of a pilot program.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Establishment of a pilot... Establishment of a pilot program. This subpart governs the Forest Service's pilot program for the disposal of... of Title III of H.R. 3423)), as amended in 2004 by Section 335 of Public Law 108-108. The...

  8. 9 CFR 2.75 - Records: Dealers and exhibitors.

    Science.gov (United States)

    2010-01-01

    ... of, including by euthanasia; (vi) The official USDA tag number or tattoo assigned to a dog or cat..., death, euthanasia, or donation. (2) Each dealer and exhibitor shall use Record of Aquisition and...

  9. Dicty_cDB: VHD275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available vkvlkkisimklkkrkdkknlerecgktk*skrcsktkn Translated Amino Acid sequence (All Frames) Frame A: nnnnnnnnnnnnnnk...n*rfkentkd*qqkvkvlkkisimklkkrkdkknlerecgktk*skrcsktkn Frame B: ttttttttttttttnktkitittsttttsrrtsfttyik***i*k

  10. 40 CFR 180.275 - Chlorothalonil; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ... Apricot 0.5 Asparagus 0.1 Banana (NMT 0.05 ppm in edible pulp) 0.5 Bean, dry, seed 0.1 Bean, snap... with husks removed 1 Cranberry 5.0 Ginseng 4.0 Horseradish 4.0 Lentil 0.10 Lychee 15 Mango 1.0...

  11. Dicty_cDB: AFJ275 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ary Heliocidaris erythrogramma cDNA 3', mRNA sequence. 32 1.5 2 AE017339 |AE01733...7E17 in linkage group 8. 36 0.73 4 BM322107 |BM322107.1 RN708T7 Sea urchin radial nerve Lambda Zap cDNA libr

  12. Cruise Report, Townsend Cromwell, Cruise 02-01 (TC-275)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Personnel from the Coral Reef Ecosystem Investigation (CRED), Honolulu Laboratory (HL), National Marine Fisheries Service (NMFS), and NOAA conducted reef...

  13. 论未成年人轻罪犯罪记录封存制度——我国新《刑事诉讼法》第275条之理解与适用%Analysis about System of Sealing Up for Safekeeping Misdemeanor Criminal Record of Minors

    Institute of Scientific and Technical Information of China (English)

    曾新华

    2012-01-01

    未成年人轻罪犯罪记录封存制度的适用对象除被判处五年有期徒刑以下刑罚的未成年犯外,未成年人相对不起诉和附条件不起诉记录封存也应参照适用,而且,从长远来看,应适用于所有未成年人;在法律效力上应严格限定但书中“国家规定”的范围,并协调与其他相关法律的关系;适用主体除公安机关、检察院、法院和未成年犯管教所外,还包括知晓未成年人犯罪记录的有关机关、单位以及当事人、辩护人、诉讼代理人和其他知晓其犯罪记录的个人。为充分发挥该制度的重要价值,应当将其“升级”为未成年人犯罪记录消灭制度。%The system of sealing up for safekeeping misdemeanor criminal record of minors is a major develop- ment of the minor criminal justice system. In addition to minors who were sentenced for fixed - term imprisonment of not more than five years, the system is applicable to the minors against whom a People's Procuratorate decides not to initiate a prosecution in accordance with the provisions of the second paragraph of Article 173 and Article 271 of the Criminal Procedure Law, and in the long term, the system shall be applied to all minors; the scope of "State regulations" in the provision of Article 275 of the Law shall be strictly limited, and coordinate with other relevant laws; In the addition to the public security organs, the peopleg procuratorates, the peopleg court and the reformato- ry for juvenile delinquents, the relevant organs, units and the parties, defenders, agents ad litem and other individ- uals who knew the criminal records of minors should seal up for safekeeping misdemeanor criminal record of minors. In order to give full play to the important value and significance of the system, it should be "upgraded" the eradica- tion system for the criminal records of minors.

  14. OC275L01: WHOI cruise 275 leg 01 aboard the R/V Oceanus from 1996-03-08 - 1996-03-22 (NODC Accession 0078919)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  15. 综合治疗肩周炎275例疗效观察%Complex therapy bursitis in shoulder 275 example curative effect observation

    Institute of Scientific and Technical Information of China (English)

    康永华; 吴晓峰

    2011-01-01

    肩周炎是常见病,多发病,治疗方法有很多种,往往单一疗效不确定,严重影响患者生活质量.笔者根据多年临床经验和体会,总结一套行之有效的综合治疗肩周炎方法,能够较快缓解病痛,直至治愈.下面详细介绍治疗方法,以供参考应用.

  16. 78 FR 275 - Airworthiness Directives; REIMS Aviation S.A. Airplanes

    Science.gov (United States)

    2013-01-03

    ... INFORMATION CONTACT: Albert Mercado, Aerospace Engineer, FAA, Small Airplane Directorate, 901 Locust, Room 301, Kansas City, Missouri 64106; telephone: (816) 329-4119; fax: (816) 329-4090; email: albert.mercado@faa... requested using the procedures found in 14 CFR 39.19. Send information to ATTN: Albert Mercado,...

  17. SU-E-T-275: Dose Build Up and Bolusing Characteristics for Total Body Irradiation Dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Butson, M; Pope, D; Whitaker, M [Chris O’Brien LifeHouse, Sydney, NSW (Australia)

    2015-06-15

    Purpose: Total Body Irradiation (TBI) treatments are mainly used in a preparative regimen for haematopoietic stem cell (or bone marrow) transplantation. Our standard regimen is a 12 Gy / 6 fraction bi-daily technique. To evaluate the delivered dose homogeneity to the patient, EBT3 Gafchromic film is positioned at the head, neck, chest, pelvis and groin for all fractions. This work investigates and quantifies the build-up dose characteristics at TBI distances and requirements for in-vivo dosimetry bolusing. Methods: Percentage dose build up characteristics of photon beams have been investigated at large extended SSD’s using parallel plate ionisations chambers (Attix) and EBT3 Gafchromic film. Measurements were made to open fields at different field sizes as well as large 40cm × 40cm fields with differing scatter conditions such as the introduction of standard Perspex scattering plates at different distances to the measurement point. Results: Percentage surface dose measured values for open fields at 300 cm SSD were found to range from 20 % up to 65.5 % for fields of 5 cm × 5 cm to 40 cm × 40 cm. With the introduction of 1cm Perspex scattering plates used in TBI treatments the surface dose values increased up to 83% to 90%, depending on the position of the Perspex scattering plate compared to the measurement point. Our work showed that at least 3mm water equivalent bolus / scatter material should be placed over the EBT3 for accurate dose assessment for TBI treatments. Conclusion: Build up dose characteristics exist at long (300cm) SSD’s including treatments using Perspex scattering plates placed at various distances form the patient during TBI treatment. Top accurately assess the applied dose during treatment, in-vivo dosimeters such as Gafchromic EBT3 should have at least 3mm bolus / scatter material placed over them to measure actual applied doses.

  18. 40 CFR 80.275 - How are allotments generated and used?

    Science.gov (United States)

    2010-07-01

    ... achieve compliance with the transferee's corporate pool average standard or be converted to credits... discounted by 50 percent. The discounted allotments may be used to demonstrate compliance with the corporate... allotments for use in demonstrating compliance with the corporate pool average standard in 2005, but...

  19. 17 CFR 275.203-1 - Application for investment adviser registration.

    Science.gov (United States)

    2010-04-01

    ..., substantial changes to Part II of Form ADV. Thus, the rules for preparing, delivering, and offering Part II... materially inaccurate. State law may continue to require you to file Part II with the appropriate State...) When filed. Each Form ADV is considered filed with the Commission upon acceptance by the IARD....

  20. Determination of the curves, torque harnesses of performance of an agricultural tractor Massey Ferguson MF 275

    Energy Technology Data Exchange (ETDEWEB)

    Paula, Vanderson Rabelo de [Universidade de Sao Paulo (ESALQ/USP), Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz; Silva, Breno Alves; Santos, Thiago Castro Vidal dos; Porto, Rodrigo Padovani; Volpato, Carlos Eduardo Silva; Barbosa, Jackson Antonio [Universidade Federal de Lavras (UFLA), MG (Brazil)

    2008-07-01

    The globalization of the economy has approached the markets and one of the consequences of this approach is the entrance of new equipment and highly competitive machines in cost terms. This is the same reality of the Brazilian agricultural sector that today counts on new options of machines and very interesting implements of the point of view of the acquisition cost. In this context, this work aimed at the dynamometric assay of an agricultural tractor for attainment of its curves of torque, power using the B100 soybean fuels, B100 olive, B100 diesel. (author)

  1. The Gow-Gates mandibular block. Evaluation after 4,275 cases.

    Science.gov (United States)

    Malamed, S F

    1981-05-01

    The Gow-Gates mandibular block, introduced in the United States in 1973, represents the first new approach to intraoral regional anesthesia in many years. The technique is being taught at most United States dental schools. This article presents a clinical evaluation of the Gow-Gates technique after 5 years of application and more than 4,000 cases. Advantages of this technique over the conventional inferior alveolar nerve block include a greater success rate, decreased positive aspiration rate, and fewer postinjection problems.

  2. 32 CFR Appendix G to Part 275 - Releasing Information Obtained From Financial Institutions

    Science.gov (United States)

    2010-07-01

    ... SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS OBTAINING INFORMATION FROM FINANCIAL INSTITUTIONS: RIGHT TO... Financial Institutions A. Financial records obtained under 12 U.S.C. chapter 35 shall be marked: “This... 32 National Defense 2 2010-07-01 2010-07-01 false Releasing Information Obtained From...

  3. 17 CFR 275.206(3)-2 - Agency cross transactions for advisory clients.

    Science.gov (United States)

    2010-04-01

    ..., receive commissions from, and have a potentially conflicting division of loyalties and responsibilities... of such other remuneration will be furnished upon written request of such customer; (3)...

  4. 7 CFR 275.23 - Determination of State agency program performance.

    Science.gov (United States)

    2010-01-01

    ... national weighted mean negative case error rate for the prior fiscal year; (ii) Beginning with Fiscal Year... case error rate less than the national weighted mean negative case rate for the prior fiscal year will... required sample size expressed as a decimal value, and S1 is the standard error of the State agency...

  5. 17 CFR 275.204-2 - Books and records to be maintained by investment advisers.

    Science.gov (United States)

    2010-04-01

    ... reasons therefor. (12)(i) A copy of the investment adviser's code of ethics adopted and implemented... record of any violation of the code of ethics, and of any action taken as a result of the violation; and... investment adviser on: (i) Micrographic media, including microfilm, microfiche, or any similar medium; or...

  6. 32 CFR Appendix D to Part 275 - Obtaining Access By Search Warrant

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) MISCELLANEOUS OBTAINING INFORMATION FROM FINANCIAL INSTITUTIONS: RIGHT TO FINANCIAL PRIVACY ACT... of Criminal Procedure. B. Unless a delay of notice has been obtained under provisions of Appendix H... rights under the Right to Financial Privacy Act of 1978.” C. In any state or territory of the...

  7. Environmental Assessment: Employment of the 2.75-Inch Rocket at Saylor Creek Air Force Range

    Science.gov (United States)

    2007-06-01

    78 Dishwasher 75 Vacuum Cleaner 70 Hair Dryer 70 Intrusive; interferes with telephone conversation Normal Conversation 50-65 Quiet Office 50...Ranunculus glaberrimus X Yes Hornseed buttercup Ranunculus testiculatus X Yes Russian thistle Salsola kali X Yes Tumble mustard Sisymbrium

  8. Strategic Defense Initiative: Splendid Defense or Pipe Dream? Headline Series No. 275.

    Science.gov (United States)

    Armstrong, Scott; Grier, Peter

    This pamphlet presents a discussion of the various components of President Reagan's Strategic Defense Initiative (SDI) including the problem of pulling together various new technologies into an effective defensive system and the politics of the so-called "star wars" system. An important part of the defense initiative is the "layered" defense…

  9. 17 CFR 275.202(a)(11)-1 - Certain broker-dealers.

    Science.gov (United States)

    2010-04-01

    ... connection with providing financial planning services and: (i) Holds itself out generally to the public as a financial planner or as providing financial planning services; (ii) Delivers to the customer a financial... connection with financial planning services; or (3) Exercises investment discretion, as that term is...

  10. 人血白蛋白275例临床应用调查分析

    Institute of Scientific and Technical Information of China (English)

    徐峰

    2013-01-01

    目的 分析人血白蛋白的临床应用情况,评价其使用的合理性.方法 回顾性调查2012年7-9月10 g人血白蛋白的应用情况,结合美国医院大学联合会(UHC)制定的《人血白蛋白、非白蛋白胶体及晶体溶液使用指南》、人血白蛋白药品说明书及浙江省医疗保险人血白蛋白限用规定进行分析.结果 癌症患者使用人数最多,占46.55%;其次为低蛋白血症,占12.00%;用药量和用药人数居前5位的科室为普外科、心外科、胸外科、肿瘤内科和重症监护病房共有用药人数142例(51.6%);使用人血白蛋白前患者血清白蛋白分布主要集中在26~30g/L.结论本次调查显示人血白蛋白的临床应用基本合理,但仍存在一些误区,有待积极干预.

  11. 17 CFR 275.206(4)-2 - Custody of funds or securities of clients by investment advisers.

    Science.gov (United States)

    2010-04-01

    ... management or policies of a person, whether through ownership of securities, by contract, or otherwise...; and (iii) Does not have, and has not had within the past two years, a material business relationship... in customer accounts; (iii) A futures commission merchant registered under section 4f(a) of...

  12. The relevance of uniform reporting in oral leukoplakia: Definition, certainty factor and staging based on experience with 275 patients

    NARCIS (Netherlands)

    Brouns, E.R.E.A.; Baart, J.A.; Bloemena, E.; Karagozoglu, H.; van der Waal, I.

    2013-01-01

    The aim of the present study was to evaluate the definition of oral leukoplakia, proposed by the WHO in 2005 and taking into account a previously reported classification and staging system, including the use of a Certainty factor of four levels with which the diagnosis of leukoplakia can be establis

  13. 17 CFR 275.206(4)-4 - Financial and disciplinary information that investment advisers must disclose to clients.

    Science.gov (United States)

    2010-04-01

    ... such action involved: an investment-related business; fraud, false statements, or omissions; wrongful... course of business within the meaning of section 206(4) of the Act (15 U.S.C. 80b-6(4)) for any... caused an investment-related business to lose its authorization to do business; or (ii) Was found to...

  14. Environmental Assessment for Travis AFB C-17 Use of Instrument Routes 264, 275, 280, 281 , and 282 in Central Nevada

    Science.gov (United States)

    2013-09-01

    Effects on Small Mammals …………………………………………. E-10 Table E-5. Sound Thresholds for Effects on Reptiles and Amphibians ………………………………. E-12 Table F-1. Steady A...Publication, Area Planning, Military Training Routes, North and South America . Table 3-3 lists the altitude structure and hours of operation of the SUA...to noise from aircraft. A few reptiles and amphibians have also been studied for aircraft noise response. There are no known effects of low level

  15. NUCLEAR CHEMISTRY: Element 107 Leaves the Table Unturned.

    Science.gov (United States)

    Service, R F

    2000-08-25

    This week, an international team of chemists reported on the first successful analysis of the chemical properties of bohrium, element 107. The results matched predictions, postponing scientists' hopes of seeing interesting deviations from theory among ultraheavy elements.

  16. Radiation-associated circulatory disease mortality in a pooled analysis of 77,275 patients from the Massachusetts and Canadian tuberculosis fluoroscopy cohorts

    Science.gov (United States)

    Tran, Van; Zablotska, Lydia B.; Brenner, Alina V.; Little, Mark P.

    2017-01-01

    High-dose ionising radiation is associated with circulatory disease. Risks associated with lower-dose (Tuberculosis patients in Canada and Massachusetts received multiple diagnostic x-ray fluoroscopic exposures, over a wide range of ages, many at doses <0.5 Gy. We evaluated risks of circulatory-disease mortality associated with <0.5 Gy radiation exposure in a pooled cohort of 63,707 patients in Canada and 13,568 patients in Massachusetts. Under 0.5 Gy there are increasing trends for all circulatory disease (n = 10,209; excess relative risk/Gy = 0.246; 95% CI 0.036, 0.469; p = 0.021) and for ischaemic heart disease (n = 6410; excess relative risk/Gy = 0.267; 95% CI 0.003, 0.552; p = 0.048). All circulatory-disease and ischaemic-heart-disease risk reduces with increasing time since exposure (p < 0.005). Over the entire dose range, there are negative mortality dose trends for all circulatory disease (p = 0.014) and ischaemic heart disease (p = 0.003), possibly due to competing causes of death over this dose interval.These results confirm and extend earlier findings and strengthen the evidence for circulatory-disease mortality radiation risk at doses <0.5 Gy. The limited information on well-known lifestyle/medical risk factors for circulatory disease implies that confounding of the dose trend cannot be entirely excluded. PMID:28287147

  17. The synchronization of palaeoclimatic events in the North Atlantic region during Greenland Stadial 3 (ca 27.5 to 23.3 kyr b2k)

    DEFF Research Database (Denmark)

    Hibbert, F.D.; Peters, C.; Rasmussen, Sune Olander

    2012-01-01

    SST records demonstrates that such events may not readily be identified within the coldest stadials of the Greenland ice cores, highlights the need for carefully constructed event stratigraphies (independently tested by the use of tephra isochrones and radiocarbon) and illustrates pervasive millennial...

  18. Low Mass Dimuon Production in p-A Collisions at $\\sqrt{s} = 27.5$ GeV with NA60

    CERN Document Server

    Uras, Antonio; Oppedisano, C; Scomparin, E; Banicz, K; Damjanovic, S; David, A; Forster, A; Guettet, N; Keil, M; Lourenco, C; Martins, P; Radermacher, E; Ramalhete, P; Rosinsky, P; Shahoyan, R; Specht, H J; Castor, J; Devaux, A; Fargeix, J; Seixas, J; Sonderegger, P; Gulkanian, H; Poghosyan, T; Heuser, J M; Guichard, A; Floris, M; Li, Z; Force, P; Ferretti, A; En'yo, H; Ducroux, L; de Falco, A; Colla, A; Cortese, P; Cicalo, C; Pillot, P; Chaurand, B; Ohnishi, H; Parracho, P; Puddu, G; Veenhof, R; Serci, S; Lozano, J; Usai, G; Wohri, H K; Tieulent, R; Masoni, A; Neves, A; Manso, F

    2011-01-01

    The NA60 experiment has studied low-mass muon pair production in proton-nucleus collisions with a system of Be, Cu, In, W, Pb and U targets using a 400 GeV/$c$ proton beam at the CERN SPS. The mass spectrum is well described by the superposition of the two-body and Dalitz decays of the light neutral mesons $\\eta$, $\\rho$, $\\omega$, $\\eta'$ and $\\phi$. A new high-precision measurement of the electromagnetic transition form factors of the $\\eta$ and $\\omega$ mesons is presented, complemented with a measurement of the temperature parameter of the $\\rho$ meson in cold nuclear matter. The $\\pt$ spectra for the $\\omega$ and $\\phi$ mesons are extracted in the full $\\pt$ range accessible, up to $\\pt = 2$ GeV/$c$. The nuclear dependence of the production cross sections for the $\\eta$, $\\omega$ and $\\phi$ mesons has been investigated in terms of the power law $\\sigma_\\mathrm{pA} \\propto \\mathrm{A}^\\alpha$, and the $\\alpha$ parameter was studied as a function of $\\pt$.

  19. Dissolved organic matter fluorescence at wavelength 275/342 nm as a key indicator for detection of point-source contamination in a large Chinese drinking water lake.

    Science.gov (United States)

    Zhou, Yongqiang; Jeppesen, Erik; Zhang, Yunlin; Shi, Kun; Liu, Xiaohan; Zhu, Guangwei

    2016-02-01

    Surface drinking water sources have been threatened globally and there have been few attempts to detect point-source contamination in these waters using chromophoric dissolved organic matter (CDOM) fluorescence. To determine the optimal wavelength derived from CDOM fluorescence as an indicator of point-source contamination in drinking waters, a combination of field campaigns in Lake Qiandao and a laboratory wastewater addition experiment was used. Parallel factor (PARAFAC) analysis identified six components, including three humic-like, two tryptophan-like, and one tyrosine-like component. All metrics showed strong correlation with wastewater addition (r(2) > 0.90, p water quality in surface drinking water sources.

  20. Gene order in a 10 275 bp fragment of Yarrowia lipolytica, including adjacent YlURA5 and YlSEC65 genes conserved in four yeast species.

    Science.gov (United States)

    Sánchez, M; Domínguez, A

    2001-06-30

    We have determined the sequence of a 10275 bp DNA segment of Yarrowia lipolytica located on chromosome VI. The sequence contains six complete open reading frames (ORFs) longer than 100 amino acids and two more partial ORFs at both ends. Two of the ORFs encode for the well-characterized genes YlURA5 (orotate phosphoribosyltransferase) and YlSEC65 (encoding a subunit of the signal recognition particle). These two genes show an identical organization-located on opposite strands and in opposite orientations-in four yeast species: Saccharomyces cerevisiae, Kluyveromyces lactis, Candida albicans and Y. lipolytica. One ORF and the two partial ORFs code for putative proteins showing significant homology with proteins from other organisms. YlVI-108w (partial) and YlVI-103w show 39% and 54% identity, respectively, with YDR430c and YHR088w from S. cerevisiae. YlVI-102c (partial) shows significant homology with a matrix protein, lustrin A from Haliotis rufescens, and with the PGRS subfamily (Gly-rich proteins) of Mycobacterium tuberculosis. The three remaining ORFs show weak or non-significant homology with previously sequenced genes. The nucleotide sequence has been submitted to the EMBL database under Accession No. AI006754.

  1. 17 CFR 275.205-1 - Definition of “investment performance” of an investment company and “investment record” of an...

    Science.gov (United States)

    2010-04-01

    ...: EC14NO91.095 The same method can be extended to cases where an investment company's fiscal quarters do not... November 30, 1971: EC14NO91.096 Exhibit II (1)—Quarter ending (2)—Index value 1 (3)—Aggregate market value... editions. Upon request the Statistics Division of the Research Department of the NYSE will make this...

  2. Spin Density Matrix Elements in Exclusive rho^0 Electroproduction on 1H and 2H Targets at 27.5 GeV Beam Energy

    CERN Document Server

    Airapetian, A

    2009-01-01

    Spin Density Matrix Elements (SDMEs) describing the angular distribution of exclusive rho^0 electroproduction and decay are determined in the HERMES experiment with 27.6 GeV beam energy and unpolarized hydrogen and deuterium targets. Eight (fifteen) SDMEs that are related (unrelated) to the longitudinal polarization of the beam are extracted in the kinematic region 1 GeV^2 < Q^2 < 7 GeV^2, 3.0 GeV < W < 6.3 GeV, and -t < 0.4 GeV^2. Within the given experimental uncertainties, a hierarchy of relative sizes of helicity amplitudes is observed. Kinematic dependences of all SDMEs on Q^2 and t are presented, as well as the longitudinal-to-transverse rho^0 electroproduction cross section ratio as a function of Q^2. A small but statistically significant deviation from the hypothesis of s-channel helicity conservation is observed. An indication is seen of a contribution of unnatural-parity-exchange amplitudes; these amplitudes are naturally generated with a quark-exchange mechanism.

  3. SU-E-T-275: Radiobiological Evaluation of Intensity Modulated Radiotherapy Treatment for Locally Advanced Head and Neck Squamous Cell Carcinomas

    Energy Technology Data Exchange (ETDEWEB)

    Rekha Reddy, B.; Ravikumar, M.; Tanvir Pasha, C.R; Anil Kumar, M.R; Varatharaj, C. [Kidwai Memorial Institute of Oncology Bangalore, Karnataka (India); Pyakuryal, A [University Illinois at Chicago, Chicago, IL (United States); Narayanasamy, Ganesh [UTHSCSA, San Antonio, TX (United States)

    2014-06-01

    Purpose: To evaluate the radiobiological outcome of Intensity Modulated Radiotherapy Treatment (IMRT) for locally advanced head and neck squamous cell carcinomas using HART (Histogram Analysis in Radiation Therapy; J Appl Clin Med Phys 11(1): 137–157, 2010) program and compare with the clinical outcomes. Methods: We have treated 20 patients of stage III and IV HNSCC Oropharynx and hypopharynx with accelerated IMRT technique and concurrent chemotherapy. Delineation of tumor and normal tissues were done using Danish Head and Neck Cancer Group (DAHANCA) contouring guidelines and radiotherapy was delivered to a dose of 70Gy in 35 fractions to the primary and involved lymph nodes, 63Gy to intermediate risk areas and 56 Gy to lower risk areas, Monday to Saturday, 6 Days/week using 6 MV Photons with an expected overall treatment time of 6 weeks. The TCP and NTCP's were calculated from the dose-volume histogram (DVH) statistics using the Poisson Statistics (PS) and JT Lyman models respectively and the Resultwas correlated with clinical outcomes of the patients with mean follow up of 24 months. Results: Using HART program, the TCP (0.89± 0.01) of primary tumor and the NTCP for parotids (0.20±0.12), spinal cord (0.05±0.01), esophagus (0.30±0.2), mandible (0.35±0.21), Oral cavity (0.37±0.18), Larynx (0.30±0.15) were estimated and correlated with clinical outcome of the patients. Conclusion: Accelerated IMRT with Chemotherapy is a clinical feasible option in the treatment of locally advanced HNSCC with encouraging initial tumour response and acceptable acute toxicities. The correlation between the clinical outcomes and radiobiological model estimated parameters using HART programs are found to be satisfactory.

  4. Danish Post‐Secondary Students Use Public Libraries for Study Purposes. A review of: Pors, Niels Ole. “The Public Library and Students’ Information Needs.” New Library World 107.1226/12272 (2006: 275‐85.

    Directory of Open Access Journals (Sweden)

    Julie McKenna

    2007-09-01

    Full Text Available Objective – To determine whether and how Danish university and higher education students use public libraries for studypurposes.Design – Online survey.Setting – Post‐secondary programs in Denmark.Subjects – 1,575 students in university‐level programs or other higher education programs (vocational three‐to‐four‐year programs in Denmark.Methods – A sample of students was drawn from the national database of students by selecting every student born on the 15th of every month (approximately 4,900 students. A letter describing the study and with an invitation to fill out an online questionnaire was sent to all students in the sample. There were 1,694 valid responses (approximately 35% response rate. Students following short vocational programs were deemed to be under‐represented and these subjects were omitted from the analysis of this report,which reflects the response of 1,575 students. The online questionnaire gathered demographic details (gender, age, educational institution, study topic, study year, geographical location, access to the Internet, etc. and used 110 questions or statements to gather information about student information‐seeking behaviour related to study purposes. These included use of the physical library and satisfaction with services, use of search engines, awareness and use of library Web‐based services, study behaviour, and participation in information literacy activities. Main results – For the purposes of this study, “academic library is used as a generic term covering university libraries, research libraries, educational libraries and all other kind of libraries outside the field of public libraries” (p. 278. The survey results confirmed many of the previous international reports of student information‐seeking behaviour: 85% of students use the academic library for study purposes; fewer than 10% of all students are able to cope without any library use; students in technology and engineering, the sciences and arts, architecture and music have a higher rate of non‐use of their academic libraries; a large percentage of students access the electronic resources from home; the physical library is still considered important to students; Google is used extensively and is nearly the exclusive choice for search engine. The public library is used for study purposes by about 58 percent of all students with the highest use (76% by students in higher education institutions (HEI; students of education, social topics and psychology are very frequent public library users. Female students in HEI were the most frequent users of the public library independent of study subject or year, or any other demographic variable. Seven per cent of students rely exclusively on the public library for study purposes and first‐year HEI students in the subject areas of education, social topics and psychology are over‐represented in this group (which additionally has less Internet access from home than the other students. Students perceive nearly all aspects of service in the academic library as superior; HEI students rate ambience, electronic resources and speed of inter‐library loan provision in the public library as higher than the academic. University students give a low rating to the collections of public library, although the students use the public library principally to supplement the collections available in their academic libraries. Another high use of public libraries by HEI students is for interlibrary loans placed through the national resource sharing system. Public library reference services are used often by only one per cent of students and only two per cent use the public library on a regular basis for “study related group activities.” Conclusion – Students use physical libraries to a great extent to support their studies and students have embraced digital access to collections, especially access from home. Google is the most heavily used search engine and is used by nearly all students;use of Google complements and supplements library use. Nearly 60% of all students use public libraries for study purposes and to supplement the collections of their academic library, but they find that the public library collections are insufficient to meet their needs. The inter‐library loan policies of public libraries are more lenient and accommodating to student needs and may drive the high use of public libraries. Students form a large constituency of the public library user population and they generally rate most aspects of service as substandard to those of academic libraries. There is a call for review of the public library’s role in meeting the information needs of students, and in particular, those of HEI programs who are most dependent on the public library.

  5. Desarmamento, Desmobilização e Reintegração dos ex-combatentes no âmbito das Nações Unidas - 10.5102/uri.v4i1.275

    Directory of Open Access Journals (Sweden)

    Aline Peixoto

    2007-08-01

    Full Text Available This article is about disarmament, demobilization and reintegration (DDR of ex-combatants – activities that have recently become part of the United Nations peace operations and that are progressively receiving more attention within the Organization. The DDR is essential for the stabilization of the region and to avoid the re-incidence of the conflict. Nevertheless, it is a very complex activity (with many institutions involved and it is difficult to coordinate and to execute. Therefore, it can be concluded that this subject demands greater efforts from the United Nations in order to overcome the problems and difficulties DDR has been facing.

  6. François Paris, Les sépultures du Sahara nigérien du Néolithique à l'islamisation, Paris, ORSTOM, 1996, 2 vols., 376 p., 275 p.

    Directory of Open Access Journals (Sweden)

    Gabriel Camps

    2005-01-01

    Full Text Available Les nombreuses campagnes de fouilles entreprises par F. Paris au Niger, ont abouti à la rédaction de cet ouvrage en deux tomes. Le premier, de 376 pages est la présentation des travaux réalisés dans le Sahara nigérien, l'Azawagh, l'Aïr, le Djado… L'étude du vaste bassin de l'Azawagh et de l'importance de ses réserves en eau, permet de définir le grand épisode humide du début de l'Holocène (8000-6500 av. J.-C. Un épisode aride se situe entre 5500 et 4500 av. J.-C.. Un autre épisode, de moindr...

  7. Ab initio study of H, He, Li and Be impurity effect in tungsten Σ3{1 1 2} and Σ27{5 5 2} grain boundaries.

    Science.gov (United States)

    Setyawan, Wahyu; Kurtz, Richard J

    2014-04-02

    Density functional theory calculations were performed to investigate the effect of H, He, Li and Be impurities on the intergranular cohesion of W Σ3〈1 1 0〉{1 1 2} and Σ27〈1 1 0〉{5 5 2} grain boundaries (GBs). A rigorous search of unique interstices was performed to reveal a range of impurity behaviors. It was found that He exhibits the largest defect formation energy, however it is Li that shows the strongest tendency to segregate towards the GBs. The embrittling potency was studied using the ideal GB fracture energy (Rice-Wang) criterion (Rice and Wang 1989 Mater. Sci. Eng. A 107 23). The potency was found to depend significantly on the local atomic environment. A site-dependent concentration was used as the weighing factor to obtain an average potency as a function of temperature. It was found that the potency depends only weakly on temperature. In Σ3 H, He, Li and Be decrease fracture energy by 4%, 27%, 30% and 14%, respectively. In Σ27 H, He and Li also decrease cohesion, albeit less severely: 3%, 14% and 7%. On the other hand, Be increases cohesion in Σ27 by 3%.

  8. Automatic Parallelization of Scientific Application

    DEFF Research Database (Denmark)

    Blum, Troels

    In my PhD work I show that it is possible to run unmodified Python/NumPy code on modern GPUs. This is done by using the Bohrium runtime system to translate the NumPy array operations into an array based bytecode sequence. Executing these byte-codes on two GPUs from different vendors shows great...... performance gains. Scientists working with computer simulations should be allowed to focus on their field of research and not spend excessive amounts of time learning exotic programming models and languages. We have with Bohrium achieved very promising results by starting out with a relatively simple approach....... This has lead to more specialized methods as I have shown with the work done with both specialized, and parametrizied kernels. Both have their benefits and recognizable use cases. We achieved clear performance benefits without any significant negative impact on overall application performance. Even...

  9. Battling memory requirements of array programming through streaming

    DEFF Research Database (Denmark)

    Kristensen, Mads Ruben Burgdorff; Avery, James Emil; Blum, Troels;

    2016-01-01

    A barrier to efficient array programming, for example in Python/NumPy, is that algorithms written as pure array operations completely without loops, while most efficient on small input, can lead to explosions in memory use. The present paper presents a solution to this problem using array streaming......, implemented in the automatic parallelization high-performance framework Bohrium. This makes it possible to use array programming in Python/NumPy code directly, even when the apparent memory requirement exceeds the machine capacity, since the automatic streaming eliminates the temporary memory overhead...... streaming, yielding corresponding improvements in speed and utilization of GPGPU-cores. The streaming-enabled Bohrium effortlessly runs programs on input sizes much beyond sizes that crash on pure NumPy due to exhausting system memory....

  10. Martha Ruffini. 2007. La pervivencia de la República posible en los territorios nacionales. Poder y ciudadanía en Río Negro : Buenos Aires: Editorial de la Universidad Nacional de Quilmes. Colección Convergencia. 275 p.

    OpenAIRE

    Girbal de Blacha, Noemí M.

    2007-01-01

    Historia, Memoria, Olvido, forman parte de las representaciones del pasado y cobran hoy una renovada importancia, en una perspectiva comparada, porque la Memoria es un objeto histórico. Pierre Norá habla de “los lugares de Memoria” (no los físicos sino los espacios de reflexión), mientras Henri Ruso la asocia a la noción de trauma, usando categorías del psicoanálisis. Lo cierto es que cualquiera sea la interpretación, la Memoria (individual o colectiva) se inscribe en un pasado coherente y le...

  11. Myriam Bienenstock et Michèle Crampe-Casnabet (dir., Dans quelle mesure la philosophie est pratique. Fichte, Hegel, avec la collaboration de Jean-François Goubet Lyon, ENS Éditions (Theoria, 2000, 275 p., 22 euros.

    Directory of Open Access Journals (Sweden)

    Mathias Goy

    2006-04-01

    Full Text Available Dans sa présentation, Myriam Bienenstock évoque l’interrogation qui fait l’unité philosophique de ce recueil, issu d’un colloque qui s’est tenu en avril 1999 à la maison Heinrich Heine et à l’ENS de Fontenay/Saint-Cloud, associant des chercheurs français et étrangers autour d’une question posée par Hegel dans un fragment de 1801 (publié en 1998. Il s’agit pour Hegel d’interroger la relation de la philosophie avec la vie, le besoin de philosophie ne portant « en fin de compte, sur rien d’autr...

  12. Zakharia Katia et Cheiban Ali (dir., Savoirs et Pouvoirs : genèse des traditions, traditions réinventées, coordonnée par, Maisonneuve et Larose, Maison de l’Orient et de la Méditerranée, 2008, 275 p.

    Directory of Open Access Journals (Sweden)

    Thomas Brisson

    2009-05-01

    Full Text Available Issues d’un séminaire organisé au GREMMO (Groupe de recherches et d’études sur la Méditerranée et le Moyen-Orient, les onze contributions rassemblées par K. Zahharia et A. Cheiban font dialoguer des chercheurs issus de disciplines différentes (historiens, sociologues, politologues, anthropologues, etc. autour d’un thème aussi riche que complexe : celui de la liaison entre savoirs et pouvoirs. L’intérêt de cette étude, ce qui en constitue parfois aussi les limites, tient en grande partie dan...

  13. Drug: D04997 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 275.7286 D04997.gif Antihypertensive USP drug classification [BR:br08302] Cardiovascular Agents Alpha-adrene...D04997 Drug Methyldopate hydrochloride (USP); Aldomet (TN) C12H17NO4. HCl 275.0924

  14. Protein (Viridiplantae): 302855471 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_70544 Volvox carteri f. nagariensis MRSASICHYTICKHMPYAICKHMRSASICHY...AICKHMPYAICKHIPYAICEHMPYATCKHMRSASICDLQAYAICKHMRSHMPYAICKHMRSASICHYAICKHMPYAICKHIPYAICEHMPYATCKHMRSASICDLQAY...AICKHIRSASICDLQAYAICKHMPSVICKHMRSASICDLQAYAICDLQACAICKHMRSTSICHYAICKHMPSCHLQAYAIMRSASISHYAICKHMPSCDLQAYAIMRSASICHYAICKHMPL ...

  15. Protein (Viridiplantae): 302856498 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_71475 Volvox carteri f. nagariensis MRSAGICHMLAYAICKHMPYAICKHMPLCDL...QAYAIMRSSSICHYAICKHMQSASICHMFAYAICKHMPYAICKHMPCAICKHMPYAICGHMRSASICHMLAYAICKHMPYAICKHMPLTICKHMPLCDQQAYAICKHMPYVCICDLQAYAIMRSAGICDLQAYAIMLSAGICDLQAYVICLHMRSASICHMRSASICH ...

  16. Protein (Viridiplantae): 302855851 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_70901, partial Volvox carteri f. nagariensis MQSASICNLQAYAICDLQAYAICKHMPYAICKHHMPYAICKHMRSA...SICDLQAYAICKHMLSASICDLQAYAVCKHMRSASICCLQAYAICKHLRSASICDLQAYVICKHMRSASICHMRSASICDLQAYAVCKHMRSASICSLQAYAVCKHMQSASICDLQAYAICKHMRFASMC ...

  17. Protein (Viridiplantae): 302855547 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_70645, partial Volvox carteri f. nagariensis MRSASICHIRCASICDLQAYAT...SDVQAYAICKHMPDAICKHMPHSMCKHMRSASICDLQAYAICKHMRSASICDLQAYAICKHLPDTICKHMPHSMCKHMRSASICDLQAYAICKHMPSASICQMRSASICHIRCASICDLQAYARCDLQAYATFDVQTYAICKHLRSASICDLQAYAICKHMPHSMCKH ...

  18. Protein (Viridiplantae): 302842271 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_81968 Volvox carteri f. nagariensis MRSARICDLQAYAICDLQAYAKCKHLPNASICDLQAYAICKHMRSA...SICDLQAYAICKHMRYAICKHMHYAHMRSASICHLQAYAICDLQAYAICDLQAYAICELQAYAICAIYAICKHMRSASICNMQVYAICKHMRSASRCTYAICDLQAYAICKHMRSASICDLQAYAICKHMCCILLNHNWMVASEDTDLEEFHPLK ...

  19. Protein (Viridiplantae): 302841701 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_62437, partial Volvox carteri f. nagariensis MRSASICHIRCASICELQAYAI...CKHVRSASICDRQAYAICKHMPDTICKHMPHSMCKHMRSASICQIRPASICHIRCASICDLQAYATCKHMRAASICDRQAYAICKHMPDAICKHMPHSMCKHMRSASICQMRSASICHIRCASICDLQAYARCDLQAYAICKHMRSASICQIRCASICDL ...

  20. Protein (Viridiplantae): 302856118 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_71227 Volvox carteri f. nagariensis MRCANICDLQAYAICKHMGCASICDLQPYAICNHMRSA...SICDLQAYAMCKHMRCASICDLQAYAICKHMRCASICDLQAYAICKHMRSASICDLQAYAMCKHMRSASICDLQAYALCKHMGCASICDVQAYAMCKHMRCASICDVQAYAMCKHMRSA...SICALQAYALCKHMRFASIWDVQAYEICKHMRCASICDLQAYALCKHMRSASICDVQAYAMCKHMRSA...SICDLQAYALCKHMGCASICDVQAYAMCKHMRCASICDVQAYAMCKHMRSASICALQAYALCKHMRFASIWDVQAYEICKHMRCASICDMQTYALCKHMRSASICDVQAYVLCKYM ...

  1. Protein (Viridiplantae): 302855974 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_70990, partial Volvox carteri f. nagariensis MRSASICDLQAYAICKHLGCASICDAQAYAIWKHMRSA...SICDLQVYALCKHIGCASVCDLQAYAIICDLQAYAICKHMRCASICALQAYAICKHMRYYMRSASICDLQAYATCKHMPYAICKHMPYAICKHMPYAICKHMPYAICKHMRSASICHMRSASICDLQAYAICDLQAYAMLCLLCLL ...

  2. Protein (Viridiplantae): 302855864 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_70912 Volvox carteri f. nagariensis MRSASICDLQAYVICKHIPYAICKHTPYAICKHMPYAICKHIPLCDLQAYAIMRSA...SICNYAIGKHMPLCDLQAYAICDLQAYTICDLQAYAICDLQAYAICKHMRSASICDLQAYMICKHIICDLQAYAICKHMRSASICDLQAYAICDLQAYAICKHMPYAICKHMPYAICKHMRSASICNLQAYAICDLQAYVICKHT ...

  3. Protein (Viridiplantae): 302856745 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_71629 Volvox carteri f. nagariensis MRSASVCDLQAYAICKHMPDAICKHMPHSMCKHMRSASICDLQAYAICKHMRSA...SICDLQAYAICKHMPDAICKHMPHPMCKHMRSASICQMRSASICHIRCASICDLQAYATSDVQAYAICKHMPDAICKHMPHSMCKHMRSASICDLQAYAICKHMRSA...SICDLQAYAICKHLPDTICKHMPHSMCKHMRSASICDLQAYAICKHMPSASICQMRSAS

  4. Protein (Viridiplantae): 302852975 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available 3068:275 hypothetical protein VOLCADRAFT_68841 Volvox carteri f. nagariensis MPYAICKHMQYALCNHMQYAICKHMRSASICHMRPASMCNMRSA...SICDLQAYDKCDLQAYAICKNMPYAICKHMPYAICKHMPYAICKHMHLQAYAVCKHMPYAICKHMPYAICKHMPYAICKHMPYAICKDYNLQAYAICKHMRSA...SICDLQAYAICDLQACAICDLQAYAICKHMTNAICKHMPSARICHMRSASICHMRSASICHMRYAICDLQAYAVCKHTQSASICSL ...

  5. Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter

    Energy Technology Data Exchange (ETDEWEB)

    Gobrecht, J.; Gaeggeler, H.; Herlach, D.; Junker, K.; Kettle, P.-R.; Kubik, P.; Zehnder, A. [eds.

    2000-07-01

    lthough originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element {sup 107} Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.

  6. Gclust Server: 203310 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 203310 Bja_bll2067=nfeC Cluster Sequences - 275 nodulate formation efficiency C pro...ciency C protein Number of Sequences 1 Homologs 1 Cluste...cluster sequences Cluster Sequences Link to related sequences - Sequence length 275 Representative annotation nodulate formation effi

  7. Drug: D00196 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00196 Drug Physostigmine (USP); Eserine (TN) C15H21N3O2 275.1634 275.3461 D00196.g... D00196 Physostigmine (USP) CAS: 57-47-6 PubChem: 7847264 DrugBank: DB00981 LigandBox: D00196 NIKKAJI: J4.57

  8. A Three-Component Seismic Refraction Survey in Northwestern Arizona

    Science.gov (United States)

    1989-01-31

    United States. Amer. J. of ScL 272:97-118. 19. Burchflel, B.C. and Davis. G.A. (1975) Nature and Controls of the Cordilleran Orogenesis , Western United...1975) Nature and Controls of the Cordilleran Orogenesis , Western United States - Extensions of an Earlier Synthesis, Amer. J. of ScL 275-k275. 20

  9. Drug: D06268 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06268 Drug Trimeperidine (INN) C17H25NO2 275.1885 275.3859 D06268.gif opioid analgesic... ligand-receptor interaction map07039 Opioid analgesics map07224 Opioid receptor agonists/antagonists Target

  10. NEWS

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Textile industrial output value of the first 11 months increased27.5% The total production:from January to November,China’s35,900 large-scale(the main business income more than 20million Yuan)textile enterprises realized an industrial out-put value of4952.64billion Yuan,up27.5%,

  11. The hard ellipsoid-of-revolution fluid. I. Monte Carlo simulations - Comment

    NARCIS (Netherlands)

    Frenkel, D; Mulder, BM

    2002-01-01

    We present the results of Monte Carlo simulations on a system of hard ellipsoids of revolution with length-to-breadth ratios a/b = 3, 2.75, 2, 1.25 and b/a = 3, 2.75, 2, 1.25. We identify four distinct phases, viz. isotropic fluid, nematic fluid, ordered solid and plastic solid. The coexistence poin

  12. GETDB: 105331 [GETDB

    Lifescience Database Archive (English)

    Full Text Available 2 1 Request - cns, oenocyte. sg sg, oenocyte leg, wing margin, vein. internal semi lethal - comment...thal Also known as - Original Comments comment1:A, comment2:75B Disc (Image) - Disc (number) 0 Embryo (Image...1:A, comment2:75B - - - - Show 105331 DGRC Number 105331 Link to Original Genotype y[*] w[

  13. Domain Modeling: NP_001005851.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001005851.1 chr19 ZINC FINGER-DNA RECOGNITION: CRYSTAL STRUCTURE OF A ZIF268-DNA... COMPLEX AT 2.1 ANGSTROMS c1zaac_ chr19/NP_001005851.1/NP_001005851.1_holo_275-356.pdb blast 275K,279C,282C,

  14. Drug: D08214 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08214 Drug Metronidazole benzoate (USP); Elyzol (TN) C13H13N3O4 275.0906 275.26 D08214.gif Antiprotozoa...cs Agents against Amebiasis and other antiprotozoals Nitroimidazole derivatives Metronidazole [ATC:A01AB17 D

  15. Seasonal variation in the flux of planktic foraminifera: Sediment trap results from the Bay of Bengal, Northern Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Guptha, M.V.S; Curry, W.B.; Ittekkot, V.; Muralinath, A.S

    stream_size 15 stream_content_type text/plain stream_name J_Foramin_Res_27_5.pdf.txt stream_source_info J_Foramin_Res_27_5.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  16. Genetic and bibliographic information: KRT5 [GenLibi

    Lifescience Database Archive (English)

    Full Text Available genital, Hereditary, and Neonatal Diseases and Abnormalities (C16) > Genetic Dise...ases, Inborn (C16.320) > Skin Diseases, Genetic (C16.320.850) > Epidermolysis Bullosa (C16.320.850.275) > Ep... Diseases (C17.800) > Skin Diseases, Genetic (C17.800.827) > Epidermolysis Bullosa (C17.800.827.275) > Epide

  17. The comparative effect of an addition of a surface term to the Woods-Saxon potential on the thermodynamics of a nucleon

    CERN Document Server

    Lütfüoğlu, B C

    2016-01-01

    In this study, we reveal the difference between Woods-Saxon (WS) and Generalized Symmetric Woods-Saxon (GSWS) potentials in order to describe the physical properties of a nucleon, by means of solving Schr\\"odinger equation for the two potentials. The additional term squeezes the WS potential well, which leads an upward shift in the spectrum, resulting in a more realistic picture. The resulting GSWS potential does not merely accommodate extra quasi bound states, but also has modified bound state spectrum. As an application, we apply the formalism to a real problem, an $\\alpha$ particle confined in Bohrium-$270$ nucleus. The thermodynamic functions Helmholtz energy, entropy, internal energy, specific heat of the system are calculated and compared in both wells. The internal energy and the specific heat capacity increase, as a result of upward shift in the spectrum. The shift of the Helmholtz free energy is a direct consequence of the shift of the spectrum. The entropy decreases because of a decrement in the num...

  18. Sensor I threonine of the AAA+ ATPase transcriptional activator PspF is involved in coupling nucleotide triphosphate hydrolysis to the restructuring of sigma 54-RNA polymerase.

    Science.gov (United States)

    Schumacher, Jörg; Joly, Nicolas; Rappas, Mathieu; Bradley, Dominic; Wigneshweraraj, Siva R; Zhang, Xiaodong; Buck, Martin

    2007-03-30

    Transcriptional initiation invariably involves the transition from a closed RNA polymerase (RNAP) promoter complex to a transcriptional competent open complex. Activators of the bacterial sigma(54)-RNAP are AAA+ proteins that couple ATP hydrolysis to restructure the sigma(54)-RNAP promoter complex. Structures of the sigma(54) activator PspF AAA+ domain (PspF(1-275)) bound to sigma(54) show two loop structures proximal to sigma(54) as follows: the sigma(54) contacting the GAFTGA loop 1 structure and loop 2 that classifies sigma(54) activators as pre-sensor 1 beta-hairpin AAA+ proteins. We report activities for PspF(1-275) mutated in the AAA+ conserved sensor I threonine/asparagine motif (PspF(1-275)(T148A), PspF(1-275)(N149A), and PspF(1-275)(N149S)) within the second region of homology. We show that sensor I asparagine plays a direct role in ATP hydrolysis. However, low hydrolysis rates are sufficient for functional output in vitro. In contrast, PspF(1-275)(T148A) has severe defects at the distinct step of sigma(54) promoter restructuring. This defect is not because of the failure of PspF(1-275)(T148A) to stably engage with the closed sigma(54) promoter, indicating (i) an important role in ATP hydrolysis-associated motions during energy coupling for remodeling and (ii) distinguishing PspF(1-275)(T148A) from PspF(1-275) variants involved in signaling to the GAFTGA loop 1, which fail to stably engage with the promoter. Activities of loop 2 PspF(1-275) variants are similar to those of PspF(1-275)(T148A) suggesting a functional signaling link between Thr(148) and loop 2. In PspF(1-275) this link relies on the conserved nucleotide state-dependent interaction between the Walker B residue Glu(108) and Thr(148). We propose that hydrolysis is relayed via Thr(148) to loop 2 creating motions that provide mechanical force to the GAFTGA loop 1 that contacts sigma(54).

  19. Identification of a short interspersed repetitive element insertion polymorphism in the porcine MX1 promoter associated with resistance to porcine reproductive and respiratory syndrome virus infection.

    Science.gov (United States)

    Li, Yanping; Liang, Sen; Liu, Hao; Sun, Yi; Kang, Li; Jiang, Yunliang

    2015-08-01

    The myxovirus resistance (Mx) proteins belong to the dynamin superfamily and are important for innate host defence against RNA viruses. In this study, we demonstrate that positive elements are present in the two promoter regions of -2713 to -2565 and -688 to -431 in the porcine MX1 gene. Sequencing and alignment of the amplified porcine MX1 gene promoter region identified a short interspersed repetitive element (SINE) insertion of 275 bp at site -547. At this site, allele B (an insertion of 275 bp) is dominant in Chinese indigenous pig breeds but has a workable minor allele frequency in western lean-type pig breeds. Luciferase activity was compared between promoters with and without the insertion of the 275-bp fragment in transiently transfected MARC-145 cells. The insertion of the 275-bp fragment increased the luciferase activity significantly (P MX1 gene promoter region is a potential DNA marker for PRRS resistance in pigs.

  20. TMFunction data: 233 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available Biol Chem. 2000 Jul 14;275(28):21017-24 mutagenesis ... affinity chromatography 1AJJ ... LDLR_HUMAN (P01130) Helix ... ligand binding site; surface exposed; acidic residue; conserved

  1. TMFunction data: 238 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available HC. J Biol Chem. 2000 Jul 14;275(28):21017-24 mutagenesis ... affinity chromatography 1AJJ ... LDLR_HUMAN (P01130) Helix ... ligand binding site; surface exposed; acidic residue; conserved

  2. TMFunction data: 237 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available HC. J Biol Chem. 2000 Jul 14;275(28):21017-24 mutagenesis ... affinity chromatography 1AJJ ... LDLR_HUMAN (P01130) Helix ... ligand binding site; surface exposed; acidic residue; conserved

  3. TMFunction data: 234 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available Biol Chem. 2000 Jul 14;275(28):21017-24 mutagenesis ... affinity chromatography 1AJJ ... LDLR_HUMAN (P01130) Helix ... ligand binding site; surface exposed; acidic residue; conserved

  4. TMFunction data: 239 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available HC. J Biol Chem. 2000 Jul 14;275(28):21017-24 mutagenesis ... affinity chromatography 1AJJ ... LDLR_HUMAN (P01130) Helix ... ligand binding site; surface exposed; acidic residue; conserved

  5. 76 FR 10165 - Endangered and Threatened Wildlife and Plants; 12-Month Finding on a Petition To List Astragalus...

    Science.gov (United States)

    2011-02-23

    ... the Livestock Grazing section above), wildlife, or insects. However, we do not ] believe herbivory... reproduction rates (Ellstrand and Elam 1993, entire; Wilcock and Neiland 2002, p. 275). Lower genetic...

  6. 76 FR 27910 - Modification of the Significant New Uses of 2-Propen-1-one, 1-(4-morpholinyl)-

    Science.gov (United States)

    2011-05-13

    ... show photographic identification, pass through a metal detector, and sign the EPA visitor log. All... number 275 gloves have been tested in accordance with the American Society for Testing Materials...

  7. Comparison of Intravenous Paracetamol and Tramadol in Children Undergoing Major Abdominal Surgery

    Directory of Open Access Journals (Sweden)

    Aysu Aydogan

    2015-06-01

    Conclusion: It was concluded that, intravenous paracetamol was provided effective analgesia but it was not superior to intravenous tramadol in children undergoing major abdominal surgery. [Cukurova Med J 2015; 40(2.000: 275-281

  8. 77 FR 66069 - Veterans' Group Life Insurance (VGLI) No-Health Period Extension

    Science.gov (United States)

    2012-11-01

    ...,'' which refer to Retired Reservist SGLI, which was discontinued by Public Law 104-275 as an independent..., 2012, for publication. List of Subjects in 38 CFR Part 9 Life insurance, Military personnel,...

  9. 77 FR 41953 - Representative Edward J. Markey; Filing of Food Additive Petition

    Science.gov (United States)

    2012-07-17

    ... CONTACT: Vanee Komolprasert, Center for Food Safety and Applied Nutrition (HFS-275), Food and Drug.... Background Under section 409(b)(5) of the Federal Food, Drug, and Cosmetic Act (the FD&C Act) (21 U.S.C....

  10. Increased postprandial energy expenditure in obese women after peroral K- and Mg-phosphate.

    Science.gov (United States)

    Jaedig, S; Lindgärde, F; Arborelius, M

    1994-01-01

    Energy expenditure (EE) was studied in 15 obese (BMI > 27.5, median 29.2) and 15 lean (BMI magnesium-phosphate to glucose increases the postprandial thermogenesis in obese postmenopausal women, but not in lean ones.

  11. A mtDNA-based phylogeny of the brown algal genus Fucus (Heterokontophyta; Phaeophyta)

    NARCIS (Netherlands)

    Coyer, JA; Hoarau, G; Oudot-Le Secq, MP; Stam, WT; Olsen, JL; Oudot-LeSecq, M.-P.

    2006-01-01

    Species of Fucus are among the dominant seaweeds along Northern Hemisphere shores, but taxonomic designations often are confounded by significant intraspecific morphological variability. We analyzed intra- and inter-specific phylogenetic relationships within the genus (275 individuals representing 1

  12. Morphologic and anatomic features of new breeding lines of cucumber var. Borszczagowski

    Directory of Open Access Journals (Sweden)

    Jolanta Lauk

    2014-02-01

    Full Text Available Four growth type mutants 2-75, W-SK, W-19, W-97 obtained from seeds of Cucumis sativus var. Borszczagowski treated with ethylene imine were studied. These mutants represented two types of growth: intensive (2-75 and dwarf (W-SK, W-19, W-97. The exuberant growth of mutant 2-75 was the result of internode elongation, intensive production of lateral shoots, enlargement of leaf and number of vascular bundles (11 as compared with 9 in the remaining mutants. The dwarfness of W-SK, W-19, W-97 mutants was caused by strong shoot reduction resulting from decreased length and number of internodes, limiting of lateral shoot production, smaller and darker leaf blade. The mutants produced fruits which differed in shape, dimension and colouring. Moreover, the fruits of mutant 2-75 were characterized by the presence of empty chambers in the endocarp.

  13. Impact of transporters in oral absorption

    DEFF Research Database (Denmark)

    Gram, Luise K; Rist, Gerda Marie; Steffansen, Bente

    2009-01-01

    was to investigate whether transporters were involved in the intestinal absorption of an organic anion A275 and to compare the impact of interactions related to transporters in the Caco-2 cell model versus the in vivo rat model of intestinal absorption. In both models, it was investigated whether intestinal...... permeation of A275 was concentration dependent and affected by inhibitors or competitive organic anions. Interactions related to transporters in intestinal permeation was clearly demonstrated in the Caco-2 cell model but was not directly evident for in vivo rat absorption. However, an observed biphasic...... in vivo absorption and a large intervariability between rats might mask a dose-dependent absorption of A275. To avoid these suggested interactions, a dose of at least 10 mg/kg, which saturates the intestinal transporters involved in A275 absorption, should be administered, but at doses below that the risk...

  14. 76 FR 58827 - Announcement of Funding Awards; Fair Housing Initiatives Program Fiscal Year (FY) 2009

    Science.gov (United States)

    2011-09-22

    ..., color, religion, sex, handicap, familial status or national origin in the sale, rental, or financing of... Tennessee Fair Housing Council, Inc.: 107 Music City Circle, (615) 874-2344 4 275,000.00 Nashville, TN...

  15. Stimulating Personal Development and Knowledge Sharing (editorial special issue)

    NARCIS (Netherlands)

    Koper, Rob; Stefanov, Krassen; Dicheva, Darina

    2010-01-01

    Koper, R., Stefanov, K., & Dicheva, D. (2009). Stimulating Personal Development and Knowledge Sharing (editorial) [Special issue]. International Journal of Continuing Engineering Education and Life-Long Learning (IJCEELL), 19(Nos. 4/5/6), 271-275.

  16. Joint swelling

    Science.gov (United States)

    ... chap 275. Raftery AT, Lim E, Ostor AJK. Joint disorders. In: Raftery AT, Lim E, Ostor AJK, eds. ... A.M. Editorial team. Related MedlinePlus Health Topics Joint Disorders Browse the Encyclopedia A.D.A.M., Inc. ...

  17. CHLOROPHYLL A, growth rate and graze rate (or grazing rate) site samples data collected in the Gulf of Alaska on the ALPHA HELIX cruises HX242, HX244 and others as part of the NEP project from 2001-04-18 to 2003-08-10 (NODC Accession 0114241)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0114241 includes site samples and biological data collected aboard the ALPHA HELIX during cruises HX242, HX244, HX247, HX271 and HX275 in the Gulf of...

  18. Disease: H01178 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available . (secondary/wound myiasis) Turpentine oil (Oral myaisis) Gatifloxacin (Ophthalmo...gadge AP, Chande MS, Bhalerao S, Tamgadge S Oral myiasis. Contemp Clin Dent 1:275-6 (2010) PMID:22124072 (de

  19. SALINITY, WATER TEMPERATURE, FLUORESCENCE, PHOTOSYNTHETIC ACTIVE RADIATION (PAR) and other profile data collected in the Gulf of Alaska on the ALPHA HELIX cruises HX242, HX244 and others as part of the NEP project from 2001-04-18 to 2003-08-11 (NODC Accession 0115255)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0115255 includes profile, biological and physical data collected aboard the ALPHA HELIX during cruises HX242, HX244, HX247, HX271 and HX275 in the...

  20. 77 FR 23484 - Agency Information Collection Activities; Proposed Collection; Comment Request; Medical Device...

    Science.gov (United States)

    2012-04-19

    ... percent of women in America reported being obese in 2010. This represents an increase from 27.5 percent..., disease history, and weight- management history. There is no cost to respondents other than about...

  1. 76 FR 37150 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-06-24

    ... Hill Rd., Wesley Hills, 11000451 Saratoga County Best, Abraham, House, 113 Vischer Ferry Rd., Vischer.... & Lakeshore Dr., New Orleans, 85003186 NEBRASKA Douglas County South Omaha Bridge, US 275/NE 92 over...

  2. Drug: D04861 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04861 Mixture, Drug Cresol - formalin - clove oil - zinc oxide mixt; Palpack V (TN...preparations 275 Pulp capping agents 2750 Pulp capping agents D04861 Cresol - formalin - clove oil - zinc oxide mixt PubChem: 17398199 ...

  3. Prevalence of Helicobacter pylori in Children and Their Family Members in a District in Turkey

    OpenAIRE

    CEYLAN, Abdullah; Kırımi, Ercan; Tuncer, Oğuz; Türkdoğan, Kürşat; Arıyuca, Sevil; Ceylan, Nesrin

    2007-01-01

    The aim of this study was to determine the prevalence of Helicobacter pylori among children and their family members and to evaluate some epidemiologic characteristics. The study included 275 children, aged 1-15 year(s), suffering from different gastrointestinal complaints. Blood serology and stool antigen testing were used for the diagnosis of infection due to H. pylori. Sixty-five (23.6%) of the 275 children were positive for H. pylori, and this positivity had a significantly increasing cor...

  4. Complete genome sequences of three strains of coxsackievirus a7.

    Science.gov (United States)

    Ylä-Pelto, Jani; Koskinen, Satu; Karelehto, Eveliina; Sittig, Eleonora; Roivainen, Merja; Hyypiä, Timo; Susi, Petri

    2013-04-11

    Genomes of three strains (Parker, USSR, and 275/58) of coxsackievirus A7 (CV-A7) were amplified by the long reverse transcription (RT)-PCR method and sequenced. While the sequences of Parker and USSR were identical, the similarities of 275/58 to the CV-A7 reference sequence, accession no. AY421765, were 82.6% and 96.2% for nucleotides and amino acids, respectively.

  5. PM Raman fiber laser at 1679 nm

    DEFF Research Database (Denmark)

    Svane, Ask Sebastian; Rottwitt, Karsten

    2012-01-01

    We demonstrate a PM Raman fiber laser emitting light at 1679 nm. The laser has an slope efficiency of 67 % and an output power of more than 275mWwith a 27 pm linewidth.......We demonstrate a PM Raman fiber laser emitting light at 1679 nm. The laser has an slope efficiency of 67 % and an output power of more than 275mWwith a 27 pm linewidth....

  6. NCBI nr-aa BLAST: CBRC-CINT-01-0130 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-CINT-01-0130 ref|ZP_01274834.1| HylII [Lactobacillus reuteri 100-23] ref|YP_00...1271372.1| channel protein, hemolysin III family [Lactobacillus reuteri F275] gb|EAS88198.1| HylII [Lactobacillus... reuteri 100-23] gb|ABQ83035.1| channel protein, hemolysin III family [Lactobacillus reuteri F275] ZP_01274834.1 2.9 25% ...

  7. Capacity analysis for high-speed terahertz wireless communications

    DEFF Research Database (Denmark)

    Dogadaev, Anton Konstantinovich; Lavrinenko, Andrei; Tafur Monroy, Idelfonso

    2012-01-01

    We report on the analytical capacity analysis of terahertz wireless communications supporting 275–325 GHz frequency band. Our goal in this paper is to provide design guidelines for close proximity links with transmission capacity beyond 100 Gbit/s.......We report on the analytical capacity analysis of terahertz wireless communications supporting 275–325 GHz frequency band. Our goal in this paper is to provide design guidelines for close proximity links with transmission capacity beyond 100 Gbit/s....

  8. The effect of transport density and gender on stress indicators and carcass and meat quality in pigs

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, T.L.; Corassa, A.; Komiyama, C. M.; Araújo, C.V.; Kataoka, A.

    2015-07-01

    A total of 168 finishing pigs were used to investigate the effects of gender (barrows and gilts) and transport densities for slaughter (236, 251, and 275 kg/m²) on stress indicators and carcass and pork quality. The animals transported at 251 kg/m² (T251) presented cortisol values below those at 236 kg/m2 (T236), but no different from those at 275 kg/m2 (T275). The lactate dehydrogenase (LDH) values in pigs transported at T236 were the lowest. The blood components did not differ between T236 and T275. The pH values at 45 min (pH45) and at 24 h (pH24) postmortem were higher for pigs subjected to T236. However, the pH45 was higher at T251 than at T275, but pH24 was lower at T251 than at T275. The lightness values in the muscles of the pigs transported at T236 and T251 were higher than those at T275. Lower drip loss values were observed in the muscle of animals at T251. Carcasses of pigs at T236 contained more 1–5 cm lesions while those at T275 contained more 5–10 cmlesions in sections of loin. No significant effects of gender were found on the stress indicators, blood components, pH45, pH24, color, drip loss or carcass lesions in general. These results indicate that the pre-slaughter transport of pigs at densities of 251 kg/m² generates less physiological damage and smaller losses on carcass and pork quality irrespective of gender. (Author)

  9. Cornering the Market: Lessons from Industry about Shaping Public Opinion

    Science.gov (United States)

    2008-03-24

    challenges or Ideas that Work.73 Databases from each of these awards are filled with winners’ own submissions and provide countless examples of incredibly...Army." The Public Opinion Quarterly 5 (1941): 275-282. JSTOR . University of Texas At Austin, Austin. 30 Oct. 2007. Keyword: Army Public Relations, 275...1943), JSTOR . University of Texas At Austin, Austin. 3 Oct. 2007, 56-68. 8 Mari K. Eder, Brigadier General, U.S. Army "Toward Strategic Communication

  10. Further Constraints on the Presence of a Debris Disk in the Multiplanet System Gliese 876

    Science.gov (United States)

    2008-06-01

    Continuum Continuum Elements 5 of 6 23 of 27 Bandwidth (MHz) 128, 128 50 Synthesized beam (arcsec2) 2.75 × 2.75 1.47 × 0.93 Configuration H168 DnC , D...2453658 while epoch 2 was centered on JD 2453676. Again, Table 1 details the observations. For the first epoch, we used the hybrid DnC configuration with

  11. Wind Generated Ocean Waves

    DEFF Research Database (Denmark)

    Frigaard, Peter

    2001-01-01

    Book review: I. R. Young, Elsevier Ocean Engineering Series, Vol 2. Elsevier Science, Oxford, UK, 1999, 306 pages, hardbound, ISBN 0-08-043317-0, Dfl. 275,00 (US$ 139.50)......Book review: I. R. Young, Elsevier Ocean Engineering Series, Vol 2. Elsevier Science, Oxford, UK, 1999, 306 pages, hardbound, ISBN 0-08-043317-0, Dfl. 275,00 (US$ 139.50)...

  12. Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains.

    Science.gov (United States)

    Abed, Yacine; Pizzorno, Andrés; Bouhy, Xavier; Boivin, Guy

    2015-02-01

    Permissive neuraminidase (NA) substitutions such as R222Q, V234M and D344N have facilitated the emergence and worldwide spread of oseltamivir-resistant influenza A/Brisbane/59/2007 (H1N1)-H275Y viruses. However, the potential contribution of genetic changes in other viral segments on viral fitness remains poorly investigated. A series of recombinant A(H1N1)pdm09 and A/WSN/33 7:1 reassortants containing the wild-type (WT) A/Brisbane/59/2007 NA gene or its single (H275Y) and double (H275Y/Q222R, H275Y/M234V and H275Y/N344D) variants were generated and their replicative properties were assessed in vitro. The Q222R reversion substitution significantly reduced viral titers when evaluated in both A(H1N1)pdm09 and A/WSN/33 backgrounds. The permissive role of the R222Q was further confirmed using A/WSN/33 7:1 reassortants containing the NA gene of the oseltamivir-susceptible or oseltamivir-resistant influenza A/Mississippi/03/2001 strains. Therefore, NA permissive substitutions play a dominant role for improving viral replication of oseltamivir-resistant A (H1N1)-H275Y viruses in vitro.

  13. Properties of Group Five and Group Seven transactinium elements

    Energy Technology Data Exchange (ETDEWEB)

    Wilk, Philip A.

    2001-05-01

    The detection and positive identification of the short-lived, low cross section isotopes used in the chemical studies of the heaviest elements are usually accomplished by measuring their alpha-decay, thus the nuclear properties of the heaviest elements must be examined simultaneously with their chemical properties. The isotopes 224 Pa and 266,267 Bh have been studied extensively as an integral part of the investigation of the heaviest members of the groups five and seven of the periodic table. The half-life of 224 Pa was determined to be 855 plus/minus19 ms by measuring its alpha-decay using our rotating wheel, solid state detector system at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. Protactinium was produced by bombardment of a bismuth target. New neutron rich isotopes, 267 Bh and 266 Bh, were produced in bombardments of a 249 Bk target and their decay was observed using the rotating wheel system. The 266 Bh that was produced decays with a half-life of approximately 1 s by emission of alpha particles with an average energy of 9.25 plus/minus 0.03 MeV. 267 Bh was observed to decay with a 17 s half-life by emission of alpha-particles with an average energy of 8.83 plus/minus 0.03 MeV. The chemical behavior of hafnium, Ha (element 105) was investigated using the fast on-line continuous liquid extraction and detection system SISAK-LISSY. Hafnium was not observed in this experiment following transport and extraction. Protactinium was used as on-line test of the apparatus to determine the experimental efficiency of the entire system. Unfortunately, the amount of protactinium observed after the extraction, compared to the amount produced, was extremely small, only 2.5%. The extraction of the protactinium isotope indicated the efficiency of the apparatus was too low to observe the extraction of hafnium. The chemical behavior of oxychloride compounds of bohrium was investigated by isothermal gas adsorption chromatography in a quartz column at 180, 150

  14. An experimental paradigm opening the world of superheavy elements

    Science.gov (United States)

    Armbruster, P.; Münzenberg, Gottfried

    2012-07-01

    The history of the discovery of the six elements Z = 107 ∓ 112, bohrium, hassium, meitnerium, darmstadtium, roentgenium, and copernicium goes back to the early 1960s. An experimental method to separate and identify rare nuclear reaction products, the recoil separation, was developed and optimised for beams of fission products at European research reactors. Chemical elements beyond the then first transactinides ( Z = 104), which owe their stability to the internal structure of atomic nuclei, were predicted theoretically. A big brother of the shell-stabilised nucleus 208Pb, a spherical magic nucleus at Z = 114∓126 and N = 184, might reach lifetimes long enough to be detected. In the seventies, hunting superheavy elements (SHE) was on the agenda of nuclear chemistry. Could the Periodic Table of Elements be extended to Z = 120, and is the order of electrons in the atom still following the laws established for lighter elements? In Germany, the heavy ion accelerator (UNILAC) was built by Christoph Schmelzer and his team at GSI, Darmstadt. SHE and UNILAC met the recoil separators in 1968, and SHIP (Separator for Heavy Ion reaction Products) was ready together with the first UNILAC-beams in 1976. Recoil separation is orders of magnitude more sensitive, selective, and faster than earlier methods used to synthesise elements up to seaborgium, Z = 106. The experimental paradigm we introduced opened the world of SHEs. At SHIP we discovered and investigated the elements Z = 107∓112 in the years 1980-2000. Our laboratory was the world champion during this time. Today our experimental method is used worldwide in the search for SHEs, but the leadership went to the Russian laboratory JINR in Dubna, which extended the Periodic Table by 6 more elements to Z = 118, the candidate for the next rare gas.

  15. Synthesis of the heaviest nuclei in cold fusion reactions

    Science.gov (United States)

    Münzenberg, G.; Morita, K.

    2015-12-01

    Cold fusion of heavy ions paved the way to superheavy elements. It was proposed by Yu.Ts. Oganessian more than forty years ago in 1974 [1,2]. First experiments were carried out at JINR Dubna, starting with the reaction 40Ar + 208Pb → 248Fm* where several hundreds to thousand atoms were produced on one day. The large production rate indicating an enhancement of the fusion cross section, especially for the evaporation of two or three neutrons, proved the concept of cold-fusion with the use of the doubly magic nucleus 208Pb as a target. The Dubna experiments were extended to the transactinide region beyond rutherfordium. The breakthrough came with the separation in-flight. Two different approaches were used: kinematic separation with the velocity filter SHIP [3] at GSI Darmstadt, and with the gasfilled separator GARIS [4,5] at RIKEN. With SHIP the concept of cold fusion of massive nuclear systems was convincingly confirmed by the observation of the one-neutron evaporation channel in the production of 247Rf in an irradiation of 208Pb with 50Ti [6] in 1981 which opened the way to the transactinide region. At SHIP the elements bohrium (107) to copernicium (112) were discovered [7]. A new closed shell region around hassium was found. The RIKEN experiments started in 2002. They confirmed the GSI results and in addition improved the data on structure and production of elements hassium to copernicium significantly. The heaviest element ever created in a cold fusion reaction, Z = 113, was observed at GARIS [8,9].

  16. Use of osteoplastic material to guide bone tissue regeneration deffect.

    Science.gov (United States)

    Machavariani, A; Mazmishvili, K; Grdzelidze, T; Menabde, G; Amiranashvili, I

    2011-12-01

    The goal of research was study of restoration processes in jaw-teeth bone defects by application of osteoplastic materials in the experiment. The experiment was performed over 32 white (6-12 month old) rats; the animals were divided into 2 groups; 16 animals were enrolled in the first group; the section was performed in the edge of lower jaw; the lower jaw body was revealed. Under the effect of the dental drilling machine and the # 1 cooling mean by the fissure bohrium (distilled water) the defect of the dimension of 2x2 mm was created; the defect was washed by 0/9% saline to remove the bone sawdust; the wound was sutured tightly, in layers. The second group of the experiment was staffed with 16 animals (main group); the similar bone defect of the size 2 x 2mm was created on the rat's jaw's body. After washing of modeled defect we inserted osteopathic materials PORESORB-TCP crystals with the size of 0,6-1.0 mm the wound was sutured tightly, in layers. After the 3-rd, 15-th, 30-th and 90-th days from the date of operation there was performed X-ray and morphological examination over the animals in the control as well as the main group. The analysis of the examination performed over the experimental materials showed that in the control group in samples taken at 90th day the defects were not completely restored. In the test group in samples taken at 90th day reparative regeneration is confirmed. This is stimulated by the factor that within the main group's animals the defect regeneration process is supported with the osteoplastic material PORESORB-TCP.

  17. The Alleghanian orogeny in the southern Appalachians: Perspective from the hinterland

    Energy Technology Data Exchange (ETDEWEB)

    Secor, D.T. Jr.; Barker, C.A.; Boland, I.B.; Pray, J.R.; Steinke, T.R.; West, T.E. (Univ. of South Carolina, Columbia, SC (United States). Dept. of Geological Science); Dallmeyer, R.D. (Univ. of Georgia, Athens, GA (United States). Dept. of Geology); Dennis, A.J. (Univ. of South Carolina, Aiken, SC (United States). Dept. of Physical Science); Maher, H.D. (Univ. of Nebraska, Omaha, NE (United States). Dept. of Geography and Geology); Wright, J.E. (Rice Univ., Houston, TX (United States). Dept. of Geology and Geophysics); Sacks, P.E.

    1992-01-01

    Along the Savannah River, the southeastern edge of the exposed Appalachian orogen provides a record of Alleghanian tectonothermal activity spanning 275--315 Ma. The earliest known structure is the Modoc fault extending 250 km along the Fall Line from Lake Murray, SC to Forsyth, GA. The Modoc fault is interpreted as a low-angle normal fault kinematically related to delamination during collision between Gondwana and Laurentia. During 275--315 Ma, the Modoc fault and adjacent terranes were deformed by NW vergent folds that are interpreted to have been kinematically linked to shortening in the foreland VIA a regional decollement. Prior to 275 Ma, the Modoc fault formed along the SE side of the Savannah River terrane. Ar-40/Ar-39 muscovite plateau ages in the Savannah River terrane define a 275 Ma horizontal isothermal surface which has not been folded or tilted. The Alleghanian orogeny in the hinterland is therefore interpreted to have terminated at ca. 275 Ma. The variety of Alleghanian structures in the hinterland may be a consequence of indentor tectonics and partitioning of displacement among coeval thrust, normal, and strike-slip faults. Taken together, the structures are interpreted to indicate relative convergence and counterclockwise rotation of Gondwana during the Alleghanian orogeny.

  18. [Analysis of the mineral elements of Lactuca sativa under the condition of different spectral components].

    Science.gov (United States)

    Chen, Xiao-Li; Guo, Wen-Zhong; Xue, Xu-Zhang; Wang, Li-Chun; Li, Liang; Chen, Fei

    2013-08-01

    Mineral elements absorption and content of Lactuca sativa under different spectral component conditions were studied by ICP-AES technology. The results showed that: (1) For Lactuca sativa, the average proportion for Ca : Mg : K : Na : P was 5.5 : 2.5 : 2.3 : 1.5 : 1.0, the average proportion for Fe : Mn : Zn : Cu : B was 25.9 : 5.9 : 2.8 : 1.1 : 1.0; (2) The absorptions for K, P, Ca, Mg and B are the largest under the LED treatment R/B = 1 : 2.75, red light from fluorescent lamps and LED can both promote the absorptions of Fe and Cu; (3)The LED treatments exhibiting relatively higher content of mineral elements are R/B = 1 : 2.75 and R/W = 1 : 1 while higher dry matter accumulations are R/B = 1 : 2.75 and B/W = 1 : 1.

  19. Dicty_cDB: SLF129 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLF129 (Link to dictyBase) - - - Contig-U13374-1 SLF129Z (Link... to Original site) - - SLF129Z 482 - - - - Show SLF129 Library SL (Link to library) Clone ID SLF129 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLF1-B/SLF129Q.Seq.d/ Representative seq. ID SLF12...9Z (Link to Original site) Representative DNA sequence >SLF129 (SLF129Q) /CSM/SL/SLF1-B/SLF129Q.Seq.d/ XXXXX... SLF275 (SLF275Q) /CSM/SL/SLF2-D/SLF275Q.Seq.d/ 938 0.0 SLF129 (SLF129Q) /CSM/SL/SLF1-B/SLF129Q.Seq.d/ 938 0

  20. AcEST: DK958301 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 8. 5' end sequence. DK958301 - Show DK958301 Clone id TST39A01NGRL0030_K08 Library TST39 Length 275 Definiti...on Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0030_K08. 5' end sequence. Accession DK958301 Tissue t...25:3389-3402. Query= DK958301|Adiantum capillus-veneris mRNA, clone: TST39A01NGRL0030_K08, 5' (275 letters) ...Nucleic Acids Res. 25:3389-3402. Query= DK958301|Adiantum capillus-veneris mRNA, ...TST39A01NGRL0030_K08 275 Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0030_K0

  1. HDAC I inhibition in the dorsal and ventral hippocampus differentially modulates predator-odor fear learning and generalization

    Directory of Open Access Journals (Sweden)

    Robin K Yuan

    2015-09-01

    Full Text Available Although predator odors are ethologically relevant stimuli for rodents, the molecular pathways and contribution of some brain regions involved remain elusive. Inhibition of histone deacetylases (HDACs in the dorsal hippocampus has been shown to enhance shock-induced contextual fear learning, but it is unknown if HDACs have differential effects along the dorso-ventral hippocampal axis during predator odor fear learning. We injected MS-275, a class I HDAC inhibitor, bilaterally in the dorsal or ventral hippocampus of mice and found that it had no effects on innate anxiety in either region. We then assessed the effects of MS-275 at different stages of fear learning along the longitudinal hippocampal axis. Animals were injected with MS-275 or vehicle after context pre-exposure (pre-conditioning injections, when a representation of the context is first formed, or after exposure to coyote urine (post-conditioning injections, when the context becomes associated with predator odor. When MS-275 was administered after context pre-exposure, dorsally injected animals showed enhanced fear in the training context but were able to discriminate it from a neutral environment. Conversely, ventrally injected animals did not display enhanced learning in the training context but generalized the fear response to a neutral context. However, when MS-275 was administered after conditioning, there were no differences between MS-275 or vehicle control groups in either the dorsal or ventral hippocampus. Surprisingly, all groups displayed generalization to a neutral context, suggesting that predator odor exposure followed by the restraint necessary for the injections leads to fear generalization. These results may elucidate distinct functions of the dorsal and ventral hippocampus in predator odor-induced fear conditioning as well as some of the molecular mechanisms underlying fear generalization.

  2. The analysis of functional movement screen test for Elite Male Kayak Canoeists%优秀男子皮艇运动员功能动作筛查测试分析

    Institute of Scientific and Technical Information of China (English)

    王兆征; 刘利; 徐宇

    2015-01-01

    s:Through the literature data method, experimental method, and interview method, functional movement screen (FMS) test on the 8 men kayak athletes. the seven fundamental testing movements score: 18.25±1.28, The deep squat, hurdle step, and in-line lunge, active straight leg raise, trunk stability push-up finished good, average score: 2.63, 2.75, 2.75, 3, 2.75, shoulder mobility and rotary stability completed general, average scores are 2.12. Combining the kayak motion analysis found two is the ability to kayak need most, and provides the improvement methods.%运用文献资料法、实验法和访谈法,对8名男子皮艇运动员进行功能动作测试(FMS)。结果:7个测试动作得分18.25±1.28分,深蹲,过栏架步,前后分腿蹲,主动直膝抬腿和躯干稳定性俯撑完成的较好,平均得分:2.63、2.752.75、3、2.75分,肩部灵活性和转动稳定性得分较一般,平均分均为2.12分。结合皮艇专项运动特点与动作分析发现后两项是皮艇项目最需要的能力,并提供了改进的方法。

  3. Dipeptidyl peptidase-4 inhibitor ameliorates early renal injury through its anti-inflammatory action in a rat model of type 1 diabetes

    Energy Technology Data Exchange (ETDEWEB)

    Kodera, Ryo, E-mail: kodera@cc.okayama-u.ac.jp [Center for Innovative Clinical Medicine, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558 (Japan); Shikata, Kenichi [Center for Innovative Clinical Medicine, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558 (Japan); Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558 (Japan); Takatsuka, Tetsuharu; Oda, Kaori; Miyamoto, Satoshi; Kajitani, Nobuo; Hirota, Daisho; Ono, Tetsuichiro [Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558 (Japan); Usui, Hitomi Kataoka [Department of Primary Care and Medical Education, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558 (Japan); Makino, Hirofumi [Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558 (Japan)

    2014-01-17

    Highlights: •DPP-4 inhibitor decreased urinary albumin excretion in a rat of type 1 diabetes. •DPP-4 inhibitor ameliorated histlogical changes of diabetic nephropathy. •DPP-4 inhibitor has reno-protective effects through anti-inflammatory action. •DPP-4 inhibitor is beneficial on diabetic nephropathy besides lowering blood glucose. -- Abstract: Introduction: Dipeptidyl peptidase-4 (DPP-4) inhibitors are incretin-based drugs in patients with type 2 diabetes. In our previous study, we showed that glucagon-like peptide-1 (GLP-1) receptor agonist has reno-protective effects through anti-inflammatory action. The mechanism of action of DPP-4 inhibitor is different from that of GLP-1 receptor agonists. It is not obvious whether DPP-4 inhibitor prevents the exacerbation of diabetic nephropathy through anti-inflammatory effects besides lowering blood glucose or not. The purpose of this study is to clarify the reno-protective effects of DPP-4 inhibitor through anti-inflammatory actions in the early diabetic nephropathy. Materials and methods: Five-week-old male Sprague–Dawley (SD) rats were divided into three groups; non-diabetes, diabetes and diabetes treated with DPP-4 inhibitor (PKF275-055; 3 mg/kg/day). PKF275-055 was administered orally for 8 weeks. Results: PKF275-055 increased the serum active GLP-1 concentration and the production of urinary cyclic AMP. PKF275-055 decreased urinary albumin excretion and ameliorated histological change of diabetic nephropathy. Macrophage infiltration was inhibited, and inflammatory molecules were down-regulated by PKF275-055 in the glomeruli. In addition, nuclear factor-κB (NF-κB) activity was suppressed in the kidney. Conclusions: These results indicate that DPP-4 inhibitor, PKF275-055, have reno-protective effects through anti-inflammatory action in the early stage of diabetic nephropathy. The endogenous biological active GLP-1 might be beneficial on diabetic nephropathy besides lowering blood glucose.

  4. The calm before the storm. Insurance against climate change; Stilte voor de storm. Verzekeren tegen klimaatverandering

    Energy Technology Data Exchange (ETDEWEB)

    De Rooij, A.; Van den Bergh, J.C.J.M. [Faculteit der Economische Wetenschappen en Bedrijfskunde, Vrije Universiteit, Amsterdam (Netherlands)

    2005-06-17

    An overview is given of the consequences of climate change for insurance companies. The article is followed by two one-page reactions to this article on page 275 and page 276. [Dutch] Een overzicht wordt gegeven van de gevolgen van klimaatverandering voor de verzekeringsbranche. Het artikel wordt gevolgd door 2 reacties van ieder 1 pagina door M.H. Propper ('Aanpassen aan klimaatverandering', p. 275) , respectievelijk door D.A. Bloemendaal en M.P. Vogelsang ('Klimaatverandering. Verzekeren van buitenproportionele risico's', p. 276)

  5. Electronic and photo-electronic transport in sputter deposited MoS2 film

    Science.gov (United States)

    Wasala, Milinda; Ghosh, Sujoy; Zhang, Jie; Richie, Julianna; Mazumdar, Dipanjan; Kar, Swastik; Talapatra, Saikat

    2015-03-01

    Here we report on the electrical transport as well as photo response of large area sputter deposited few-layers of thin MoS2. Temperature dependent (55 K -275K) electronic conductivity measured on these samples show evidence of 2D Variable Range Hopping (2D-VRH) mechanism within 100K-275K. Photoconductivity measurements investigated using a continuous laser of λ = 658nm (E =1.88eV), over a broad range of illuminating laser intensity, P (0.19 μW OISE-0968405.

  6. Effects of irradiation at low temperature on V-4Cr-4Ti

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, D.J.; Snead, L.L.; Zinkle, S.J. [Oak Ridge National Lab., TN (United States)] [and others

    1996-10-01

    Irradiation at low temperatures (100 to 275{degrees}C) to 0.5 dpa causes significant embrittlement and changes in the subsequent room temperature tensile properties of V-4Cr-4Ti. The yield strength and microhardness at room temperature increase with increasing irradiation temperature. The tensile flow properties at room temperature show large increases in strength and a complete loss of work hardening capacity with no uniform ductility. Embrittlement, as measured by an increase in the ductile-to-brittle transition temperature, increases with increasing irradiation temperature, at least up to 275{degrees}C. This embrittlement is not due to pickup of O or other interstitial solutes during the irradiation.

  7. Contributions to the Data on Theoretical Metallurgy. 3. The Free Energies of Vaporization and Vapor Pressures of Inorganic Substances

    Science.gov (United States)

    1935-01-01

    an approximate vapor-pressure equation is included. 0 Liquid- Gas ((Si0.).) log P (at.)=- 13+7.65. Monosilane .-Vapor pressures of the hydride, SiB4...91 0 0 0 AImonbrom- monosilane .--Stock and Sonieski (393) (179-275*) have determined the vapor pressure of monobrom- monosilane , SiHtBr. The results are...11. P. =275.5°; A!!2,&.j5,648; AS,.6=20.5, AH,..,=5,558; AFmj,=-460. The above authors find 179.30 for the melting point. Dibrom- monosilane .-The vapor

  8. SIMPLY ANALYZE THE APPLICATION OF HART COMMUNICATOR IN INSTRUMENT%浅析HART通讯器在仪表中的应用

    Institute of Scientific and Technical Information of China (English)

    李蕾; 赵旭; 刘海岭

    2011-01-01

    This paper introduces HART protocol and function of the model 275 HART Communicator, and enumerates several application of HART communicator in actual instrument. It has active effects to feature application and popularization of the HART Communicator.%介绍了HART通讯协议及275型HART通讯器的功能,并列举了HART通讯器在冶金行业现场仪表中的几种具体应用,对HART通讯器的进一步使用和推广起到了积极的作用。

  9. Drug: D02124 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D02124 Drug Penciclovir sodium (USAN); Denavir (TN) C10H14N5O3. Na 275.0994 275.239...LOGICAL USE D06B CHEMOTHERAPEUTICS FOR TOPICAL USE D06BB Antivirals D06BB06 Penciclovir D02124 Penciclovir s... J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors J05AB13 Penciclo...vir D02124 Penciclovir sodium (USAN) USP drug classification [BR:br08302] Antivirals Antiherpetic Agents Penciclo...vir D02124 Penciclovir sodium (USAN) Antiinfectives [BR:br08307] Antivirals Anti-HSV agent DNA

  10. Evidence from Central Mexico Supporting the Younger Dryas Extraterrestrial Impact Hypothesis

    Science.gov (United States)

    2012-03-05

    Steven M. Stanley, University of Hawaii , Honolulu, HI, and approved January 31, 2012 (received for review July 13, 2011) We report the discovery in...second largest lake in Mexico, located at high elevation of 1,820 m in the northern part of the state of Michoacán within the tectonically active...and Fe, concentrated in the rind. They reach a significant peak of approximately 680∕kg at 2.75 m within the YDB layer. Above 2.75 m, the CSp persist

  11. 75 FR 68621 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-08

    ... 16, 2009. Trimline, Accountemps, Kelly, Delta, and Connection. 74,275A Welch Allyn, Inc., Also..., Incorporated, Pleasant Pairie, WI August 30, 2009. Kelly Service. 74,682 Broadview Network Rye Brook, NY........... October 13, 2009. Inc.; Monroe Staffing Services, LLC and Photo Temps. The following certifications...

  12. TMFunction data: 335 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available M. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis No accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Helix... ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  13. TMFunction data: 329 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available M. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis No accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Helix... ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  14. TMFunction data: 327 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available AM. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis yes accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Hel...ix ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  15. TMFunction data: 314 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available M. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis No accessible to aqueous phase (accessibility...) ... TXTP_YEAST (P38152) Helix ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  16. TMFunction data: 321 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available M. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis No accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Helix... ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  17. TMFunction data: 318 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available AM. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis yes accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Hel...ix ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  18. TMFunction data: 323 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available AM. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis yes accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Hel...ix ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  19. TMFunction data: 325 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available M. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis No accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Helix... ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  20. TMFunction data: 316 [TMFunction[Archive

    Lifescience Database Archive (English)

    Full Text Available M. J Biol Chem. 2000 Apr 21;275(16):12009-16 site-directed mutagenesis No accessible to aqueous phase (accessibility...) accessible to aqueous phase (accessibility) ... TXTP_YEAST (P38152) Helix... ... first order rate constant; accessibility; transmembrane domain; substrate translocation pathway

  1. Human-Robot Interaction: A Survey

    Science.gov (United States)

    2007-01-01

    itself [210, 275]. One relevant study explored how ROOMBA robots are used in practice without attempting to make operators use the robots in a specific way...Robotics. Berlin: Springer, 2003. [99] J. Forlizzi and C. DiSalvo, “Service robots in the domestic environment: A study of the Roomba vacuum in the home

  2. Isoflavonoids of the leguminosae.

    Science.gov (United States)

    Veitch, Nigel C

    2013-07-01

    This account describes 275 new isoflavonoids published between 2008 and 2011 as constituents of the Leguminosae, commenting on their source, identification, biological activity, synthesis, and ecological or chemosystematic significance. Applications of hyphenated analytical techniques to the characterisation of Leguminosae isoflavonoids are also reviewed, together with advances in biosynthetic studies. A checklist of new compounds by species is given, and 226 references are cited.

  3. Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)

    DEFF Research Database (Denmark)

    Bjerrum, Esben J; Kristensen, Anders S; Pickering, Darryl S

    2003-01-01

    On the basis of structural studies, chloro-homoibotenic acid (Cl-HIBO) was designed and synthesized. Cl-HIBO was characterized in binding and electrophysiology experiments on native and cloned subtypes of GluRs. Electrophysiological selectivities ranged from 275 to 1600 for GluR1/2 over GluR3/4. ...

  4. Understanding the Association between Future Time Perspective and Self-Regulated Learning through the Lens of Self-Determination Theory

    Science.gov (United States)

    de Bilde, Jerissa; Vansteenkiste, Maarten; Lens, Willy

    2011-01-01

    The present cross-sectional research examined a process underlying the positive association between holding an extended future time perspective (FTP) and learning outcomes through the lens of self-determination theory. High school students and university students (N = 275) participated in the study. It was found that students with an extended FTP…

  5. Operation REDWING. Technical Summary of Military Effects. Programs 1-9

    Science.gov (United States)

    1981-05-15

    uicontrolled conditions involving a water-soil Interface. Because of the radiological fallout hazard limitations imposed, there was no prospect of...high enough to show the variation in dose com- Ntations that could result from the 1.38 and 2-75 Mev gammas from Na’, which created a large portion

  6. Comparative analysis of pharmaceuticals versus industrial chemicals acute aquatic toxicity classification according to the United Nations classification system for chemicals. Assessment of the (Q)SAR predictability of pharmaceuticals acute aquatic toxicity and their predominant acute toxic mode-of-action

    DEFF Research Database (Denmark)

    Sanderson, Hans; Thomsen, Marianne

    2009-01-01

    the United Nations Global Harmonized System for classification and labeling of chemicals (GHS). Moreover, we statistically explored whether the predominant mode-of-action (MOA) for pharmaceuticals is narcosis. We found 275 pharmaceuticals with 569 acute aquatic effect data; 23 pharmaceuticals had chronic...

  7. Growth and reproductive investment of introduced Pacific oysters

    NARCIS (Netherlands)

    Cardoso, J.F.M.F.; Peralta, N.R.E.; Machado, J.P.; van der Veer, H.W.

    2013-01-01

    Growth and reproductive investment of cultured Pacific oysters Crassostrea gigas were studied in two south-western European estuaries: the Ria de Ribadeo in Spain and the Ria Formosa in Portugal. Developing gonads were found in individuals >23.5 mm shell length in the Ria Formosa and >27.5 mm shell

  8. Aerogenic Vaccination With a Burkholderia mallei Auxotroph Protects Against Aerosol-Initiated Glanders in Mice

    Science.gov (United States)

    2005-03-14

    Greenfield RA. Other bacte- rial diseases as a potential consequence of bioterrorism: Q fever, brucellosis , glanders, and melioidosis. J Okla State Med...sheep and goats . Prev Vet Med 1997;31:275–83. 15] Garmory HS, Griffin KF, Brown KA, Titball RW. Oral immunisation with live aroA attenuated Salmonella

  9. Fractal Image Filters for Specialized Image Recognition Tasks

    Science.gov (United States)

    2010-02-11

    1985) 243�275. [9] M. A. Berger and Y. Wang, Bounded semigroups of matrices, Linear Algebra and Appl. 166 (1992), 21-27. [10] I. Daubechies and J.C...Nat. Acad. Sci. 83 (1985) 1975-1977. [3] M. A. Berger and Y. Wang, Bounded semigroups of matrices, Linear Alge- bra and Appl. 166 (1992), 21-27. [4] I

  10. Violent women : A multicentre study into gender differences in forensic psychiatric patients

    NARCIS (Netherlands)

    de Vogel, Vivienne; Stam, Jeantine; Bouman, Yvonne H. A.; Ter Horst, P.R.M.; Lancel, Marike

    2016-01-01

    To gain insight into the relatively small, but increasing group of women in forensic psychiatry, a retrospective multicentre study was started gathering information from the files of 275 female patients of four Dutch forensic psychiatric hospitals on characteristics and violence risk factors. Overal

  11. Development of depressive symptoms and depression during organizational change--a two-year follow-up study of civil servants

    DEFF Research Database (Denmark)

    Netterstrøm, Bo; Blønd, Morten; Nielsen, Martin;

    2010-01-01

    On 1 January 2007, Denmark went through a major reorganization, where most of its 275 municipalities and 14 counties merged into larger units. Our study aimed to examine the development of depressive symptoms and incident depression among employees affected by this organizational change....

  12. Place-Based Stewardship Education: Nurturing Aspirations to Protect the Rural Commons

    Science.gov (United States)

    Gallay, Erin; Marckini-Polk, Lisa; Schroeder, Brandon; Flanagan, Constance

    2016-01-01

    In this mixed-methods study, we examine the potential of place-based stewardship education (PBSE) for nurturing rural students' community attachment and aspirations to contribute to the preservation of the environmental "commons." Analyzing pre- and post-experience surveys (n = 240) and open-ended responses (n = 275) collected from…

  13. An Epithelial-Derived, Integral Membrane, Kunitz-Type Serine Protease Inhibitor in Breast Cancer

    Science.gov (United States)

    2005-08-01

    an epithelial membrane serine protease. J Biol Chein 275: 36720-36725, 2000. prevents15. Lin CY, Anders J, Johnson M, and Dickson RB. Purification and...functions properly, thus trypsin-like activity. J Biol Chein 274: 18231--18236, 1999. 0 avoiding harmful effects. 17. Lin CY, Wang JK, Torri J, Dou L, Sang

  14. Parent-Child Predictors of Social Competence with Peers in Children with and without Autism

    Science.gov (United States)

    Meek, Shantel E.; Robinson, Lauren T.; Jahromi, Laudan B.

    2012-01-01

    The current study investigated the relations among parent-child joint engagement, dyadic interactive behaviors, and children's subsequent social competence with peers. Participants were 40 children (20 children with autism, and 20 developmentally-matched typical children) between the ages of 2.75 and 6.5 years. Observational coding was conducted…

  15. Eosinophilia is associated with increased all-cause mortality after a follow-up of 30 years in a general population sample

    NARCIS (Netherlands)

    Hospers, JJ; Schouten, JP; Weiss, ST; Postma, DS; Rijcken, B

    2000-01-01

    We investigated whether allergy is associated with increased all-cause mortality. Two allergy markers, peripheral blood eosinophilia (greater than or equal to 275 eosinophilic cells per mm(3)) and positive skin tests (sum score greater than or equal to 3), were available for 5,383 subjects of a coho

  16. Comparison of Numerical and Experimental Time-Resolved Near-Field Hall Thruster Plasma Properties

    Science.gov (United States)

    2014-03-06

    ABSTRACT Unclassified c. THIS PAGE Unclassified SAR 8 19b. TELEPHONE NO (include area code ) 661-275-6799 Standard Form 298 (Rev. 8-98...81, no. 7, p. 073503, 2010. [14] D. Liu, R. E. Huffman , R. D. Branam, and W. A. Hargus, “Ultra- high speed imaging of Hall thruster discharge

  17. 78 FR 67386 - Announcement of Funding Awards; Indian Community Development Block Grant Program Fiscal Year 2013

    Science.gov (United States)

    2013-11-12

    ... job Wolfe, Governer, 2025 South Gordon training. Cooper, Shawnee, OK 74801, 405-275-4030. All Mission..., Tom 600,000 HC Relocation and new homes Malson, PO Box 67, Lac du Flambeau, WI for 20 families. 54538... Rehabilitation of 23 Entity, Tom Yellow Wolf, P.O. Box 250, homeownership units and Fort Duchesne, UT 84026,...

  18. The Use of Lego Technologies in Elementary Teacher Preparation

    Science.gov (United States)

    Hadjiachilleos, Stella; Avraamidou, Lucy; Papastavrou, Stavros

    2013-01-01

    The need to reform science teacher preparation programs has been pointed out in research (Bryan and Abell in "J Res Sci Teach" 36:121-140, 1999; Bryan and Atwater in "Sci Educ" 8(6):821-839, 2002; Harrington and Hathaway in "J Teach Educ" 46(4):275-284, 1995). Science teachers are charged with the responsibility of…

  19. Extension Master Gardener Social Media Needs: A National Study

    Science.gov (United States)

    Vines, Karen A.; Jeannette, Karen; Eubanks, Emily; Lawrence, Maggie; Radhakrishna, Rama

    2016-01-01

    An online survey was conducted to assess the feasibility of providing training on the use of social media for the Extension Master Gardener (EMG) program. Volunteers (n = 1,275) and coordinators (n = 111) responded. Findings indicate the existence of sufficient interest in a nationally coordinated social media training. Inclusion of social media…

  20. The Use of Lego Technologies in Elementary Teacher Preparation

    NARCIS (Netherlands)

    Hadjiachilleos, Stella; Avraamidou, Lucy; Papastavrou, Stavros

    2013-01-01

    The need to reform science teacher preparation programs has been pointed out in research (Bryan and Abell in J Res Sci Teach 36:121-140, 1999; Bryan and Atwater in Sci Educ 8(6):821-839, 2002; Harrington and Hathaway in J Teach Educ 46(4):275-284, 1995). Science teachers are charged with the respons

  1. GLYCOGEN IN BACILLUS-SUBTILIS - MOLECULAR CHARACTERIZATION OF AN OPERON ENCODING ENZYMES INVOLVED IN GLYCOGEN BIOSYNTHESIS AND DEGRADATION

    NARCIS (Netherlands)

    KIEL, JAKW; BOELS, JM; BELDMAN, G; VENEMA, G

    1994-01-01

    Although it has never been reported that Bacillus subtilis is capable of accumulating glycogen, we have isolated a region from the chromosome of B. subtilis containing a glycogen operon. The operon is located directly downstream from trnB, which maps at 275 degrees on the B. subtilis chromosome. It

  2. Holocene eruptions of mauna kea volcano, hawaii.

    Science.gov (United States)

    Porter, S C

    1971-04-23

    Postglacial lava flows, interstratified with thick locally derived sheets of tephra, cover some 27.5 square kilometers on the south slope of Mauna Kea. Most of the volcanics were erupted about 4500 years ago and overlie a regionally extensive paleosol which developed largely during the last glaciation.

  3. Aromatised product of n-heptane. Characterization by gas chomatography

    Energy Technology Data Exchange (ETDEWEB)

    Chopra, S.K. [Indian Inst. of Petroleum, Council of Scientific and Industrial Research, Dehradun (India); Kapoor, V.B. [Indian Inst. of Petroleum, Council of Scientific and Industrial Research, Dehradun (India); Bhagat, S.D. [Indian Inst. of Petroleum, Council of Scientific and Industrial Research, Dehradun (India)

    1995-04-01

    A high resolution gas chromatography method for the analysis of the aromatised product of n-heptane has been developed. The individual aromatics were separated on OV-101 and OV-275 capillary columns. The qualitative analysis was done using correlation between retention data vs. boiling point and the literature data available. Quantitation was achieved using flame ionisation detector assuming that the relative response for all aromatics is same. Packed column of OV-275 gave group type distribution of saturate (1.2%), monoaromatics (76.6%) diaromatics 21.9% and triaromatics 0.3%. Data generated are presented as individual components, hydrocarbon groups and according to carbon number distribution. (orig.) [Deutsch] Eine hochaufloesende gaschromatographische Methode fuer die Analyse des aromatisierten Produktes von n-Heptan wurde entwickelt. Die einzelnen Aromaten wurden ueber Kapillarsaeulen OV-101 und OV-275 getrennt. Die qualitative Bestimmung wurde durchgefuehrt mittels der Korrelation zwischen Verweilzeitdaten und Siedepunkten und anhand der verfuegbaren Literaturangaben. Fuer die Quantifizierung wurde der Flammenionendetektor eingesetzt, in der Annahme einer gemeinsamen Basis der Messungen fuer alle Aromaten. Die Fuellkoerperkolonne OV-275 zeigte die Verteilung der Verbindungsgruppen an: Gesaettigte (1,2%), Monoaromaten (76,6%), Diaromaten (21,9%) und Triaromaten (0,3%). Die erhaltenen Daten sind als einzelne Komponenten und als Kohlenwasserstoffgruppen dargelegt. (orig.)

  4. Endophragmiella bogoriensis Rifai, spec. nov. (Hyphomycetes

    Directory of Open Access Journals (Sweden)

    Mien A. Rifai

    2008-12-01

    Full Text Available RIFAI, M.A. 2008. Endophragmiella bogoriensis Rifai, spec. nov. (Hyphomycetes. Reinwardtia 12 (4: 275 – 276. –– A new species of Endophragmiella is described and illustrated based on a specimen found growing on dead branchlets of Morinda citrifolia in Bogor, West Java, and compared with its closely related congeners thus far known.

  5. Environmental Effects Exceed Genetic Effects on Perceived Intensity and Pleasantness of Several Odors

    DEFF Research Database (Denmark)

    Knaapila, Antti; Tuorila, Hely; Silventoinen, Karri

    2008-01-01

    and pleasantness of cinnamon, chocolate, turpentine, and isovaleric acid (sweaty) odors by quantitative genetic modeling of odor rating data from 856 twin individuals (including 83 complete monozygotic and 275 dizygotic twin pairs) aged 10-60 years (44% males and 56% females) from Australia, Denmark, and Finland...

  6. 50 CFR 648.82 - Effort-control program for NE multispecies limited access vessels.

    Science.gov (United States)

    2010-10-01

    ... according to paragraph (k)(4)(xi) of this section. (x) Leasing by vessels fishing under a sector allocation... section, or reduced pursuant to § 648.87(b)(1)(iii). (B) For a sector vessel, Category A DAS allocated for... section. (ii) For a sector vessel, Regular B DAS are defined as 27.5 percent of the vessel's used...

  7. Homeschooling. ERIC Digest.

    Science.gov (United States)

    Lines, Patricia M.

    Homeschooling has grown over the past several decades. It is estimated that 923,700 to 1,275,098 children will be homeschooled by the 2001-02 school year. Homeschooling families come from all major ethnic, cultural, and religious backgrounds and all income levels. Homeschooling parents are commonly active in their communities and join community…

  8. Stable Hydrogen and Oxygen Isotope Ratios for Selected Sites of the U.S. Geological Survey’s NASQAN and Benchmark Surface-Water Networks

    Science.gov (United States)

    2000-01-01

    274 Ohio 03159510 Hocking River Below Athens .................................................................................275...369 12039300 North Fork Quinault River Near Amanda Park...Kanawha River At Palestine WV 54 N 39.05972 81.3903 1515 05030203 585.51 03159510 Hocking River Below Athens OH 39 N 39.32749 82.0050 957 05030204

  9. Solar energy directories

    Energy Technology Data Exchange (ETDEWEB)

    Frankena, F.

    1984-01-01

    This annotated bibliography lists 275 directories relating to solar energy and renewable energy resources. The references include the newsletters and in-house publications of small firms and groups, plans and designs for solar housing, catalogs, and directories of agencies and organizations involved in solar energy. The references are listed in alphabetical order.

  10. Gclust Server: 68684 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 68684 Ava_Ava_4151 Cluster Sequences Related Sequences(508) 275 ABC transporter-lik...e 1 9.98e-01 0.0 0.0 4.0 0.0 0.0 0.0 Show 68684 Cluster ID 68684 Sequence ID Ava_Ava_4151 Link to cluster se

  11. Is a Luxury Goods Consumption Tax Useful?

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ U.S. management consultaney firm Bain & Company has released a report show-ing in 2009 China's luxury goods market swelled by nearly 12 percent, reaching $9.6 billion and accounting for 27.5 percent of global sales.

  12. FID detection of EPR and ENDOR spectra at high microwave frequencies

    Science.gov (United States)

    Blok, H.; Akimoto, I.; Milikisyants, S.; Gast, P.; Groenen, E. J. J.; Schmidt, J.

    2009-11-01

    High-frequency pulsed EPR spectroscopy allows FID detection of EPR spectra owing to the short dead time that can be achieved. This FID detection is particularly attractive for EPR and ENDOR spectroscopy of paramagnetic species that exhibit inhomogeneously broadened EPR lines and short dephasing times. Experiments are reported for the metalloprotein azurin at 275 GHz.

  13. Oseltamivir-resistant influenza virus A (H1N1), Europe, 2007/08 season.

    NARCIS (Netherlands)

    Meijer, A.; Lackenby, A.; Hungnes, O.; Lina, B.; Werf, S. van der; Schweiger, B.; Opp, M.; Paget, J.; Kassteele, J. van de; Hay, A.; Zambon, M.

    2009-01-01

    In Europe, the 2007/08 winter season was dominated by influenza virus A (H1N1) circulation through week 7, followed by influenza B virus from week 8 onward. Oseltamivir-resistant influenza viruses A (H1N1) (ORVs) with H275Y mutation in the neuraminidase emerged independently of drug use. By country,

  14. Domain Modeling: NP_008881.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_008881.2 chrX Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP (...Form 1) c1px2b_ chrX/NP_008881.2/NP_008881.2_holo_113-417.pdb blast 188H,225K,267V,269K,273A,274H,275S,276G,

  15. Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes

    DEFF Research Database (Denmark)

    Lohmueller, Kirk E.; Sparsø, Thomas; Li, Qibin;

    2013-01-01

    It has been hypothesized that, in aggregate, rare variants in coding regions of genes explain a substantial fraction of the heritability of common diseases. We sequenced the exomes of 1,000 Danish cases with common forms of type 2 diabetes (including body mass index > 27.5 kg/m2 and hypertension)...

  16. Drug: D03308 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available benzylguanidine; PheoMIBG-I 131 (TN) C8H10IN3 278.9936 275.0896 D03308.gif Diagnostic aid; Radioactive agent...Agents affecting cellular function 43 Radioactive drugs 430 Radioactive drugs 4300 Radioactive

  17. Attitudes of Health Care Providers toward Elderly Patients with Normal Aging and Disease-Related Symptoms.

    Science.gov (United States)

    Baker, Rodney R.

    1984-01-01

    Examined preferences of 275 health care providers for working with elderly patients exhibiting symptoms of normal aging or diseases. In comparing descriptions of two hospitalized patients, physicians, nurses and social workers expressed a preference for working with patients with disease symptoms, raising concerns about geriatric care. (JAC)

  18. Dicty_cDB: CHP678 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available us laevis MGC81821 protein, m... 276 1e-72 EU850439_1( EU850439 |pid:none) Adineta vaga dihydrogenpyrimidine... ... 275 3e-72 EU652316_1( EU652316 |pid:none) Adineta vaga dihydrogenpyrimidine

  19. [Peculiarities of surgical interventions for the treatment of inflammatory and traumatic lesions in the frontal sinus].

    Science.gov (United States)

    Piskunov, S Z; Kuriatina, E I; Tarasov, I V

    2011-01-01

    This paper summarizes the experience with the treatment of 275 patients presenting with inflammatory diseases and traumatic lesions of the frontal sinus. Based on the results of the present study, recommendations have been developed designed to optimize surgical interventions for the enhancement of treatment efficiency and the prevention of relapses.

  20. Vibration of Ship Hulls Due to Wave Excitation.

    Science.gov (United States)

    1979-05-01

    Wave Induced Stress in a Ship Executing Symmetric Motions," Philosophical Transactions of the Royal Society of London, A-275, 1973, p. 1-32. 13. Boyce ...William E. and Richard C. DiPrima , Elementary Differential Equations. New York: John Wiley and Sons, 1969. 14. Comstock, John P. ed. Principles of

  1. 77 FR 53225 - Draft Environmental Impact Statement for the Proposed Seminole Tribe of Florida Fee-to-Trust...

    Science.gov (United States)

    2012-08-31

    ... development of a hotel/resort and other ancillary uses (Proposed Project). At full build-out, the proposed... dining, a 2,500 seat showroom, and a 1,000-room hotel. The hotel tower would not exceed 275 feet...

  2. Enrollment and Completions at Private Career Schools. A Factual Look at Private Career Institutions in Nebraska.

    Science.gov (United States)

    Nebraska Coordinating Commission for Postsecondary Education, Lincoln.

    A survey of 53 private career institutions in Nebraska (56 percent located in the Omaha area) revealed the following statistics for the period July 1, 1990 to June 30, 1991: (1) 9,275 students were enrolled; (2) business programs enrolled the largest percentage (35 percent) of the total student population, with business, trade, and technical…

  3. [Standardizing a protocol of magnetic resonance imaging of temporomandibular joints. Part I].

    Science.gov (United States)

    Bulanova, T V

    2004-01-01

    The paper presents the standard of a procedure for magnetic resonance imaging of temporomandibular joints, which has been used to examine 275 patients. It describes the study projections, that are most significant for visualization, and scanning protocols. Illustrations of magnetic resonance imaging of the structures of the intact temporomandibular joint are presented.

  4. Heavy Metal Music and Adolescent Suicidal Risk.

    Science.gov (United States)

    Lacourse, Eric; Claes, Michel; Villeneuve, Martine

    2001-01-01

    Studied differentiating characteristics of youth who prefer heavy metal music, worship music, and use music for vicarious release. Data for 275 secondary school students suggest that heavy metal music preference and worshipping is not related to suicidal risk when controlling for other suicide factors. Discusses findings in the context of…

  5. Reference: CURECORECR [PLACE

    Lifescience Database Archive (English)

    Full Text Available CURECORECR Quinn JM, Barraco P, Eriksson M, Merchant S. Coordinate copper- and oxygen-re...sponsive Cyc6 and Cpx1 expression in Chlamydomonas is mediated by the same element. J Biol Chem. 275: 6080-6089 (2000). PubMed: 10692397 ...

  6. Design and Integration of a Scent Delivery System in the Computer Assisted Rehabilitation Environment (CAREN)

    Science.gov (United States)

    2013-12-06

    Scents Used in Exhibits, Simulations, and Military Applications Environmental Mood 152 Musty 275 Dinosaur Dung/Iraq 160 Earth 402 Leather 681...Cordite 1095 Coffee 1433 Burnt Wire 1633 Curry 1635 Oily Chemicals/Industrial 1644 Roasting Meat 1638 Gasoline 1663 Black Pepper 1640 Burning

  7. 21 CFR 520.903b - Febantel suspension.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Febantel suspension. 520.903b Section 520.903b... DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.903b Febantel suspension. (a) Specifications. The suspension contains 9.3 percent (2.75 grams per ounce) febantel. (b) Sponsor. See 000859...

  8. Transitions into and out of Cohabitation in Later Life

    Science.gov (United States)

    Brown, Susan L.; Bulanda, Jennifer Roebuck; Lee, Gary R.

    2012-01-01

    Cohabitation among adults over age 50 is rising rapidly, more than doubling from 1.2 million in 2000 to 2.75 million in 2010. A small literature provides a descriptive portrait of older cohabitors, but no study has investigated transitions into and out of cohabitation during later life. Drawing on demographic and life course perspectives, the…

  9. The Goteborg Discotheque Fire: Posttraumatic Stress, and School Adjustment as Reported by the Primary Victims 18 Months Later

    Science.gov (United States)

    Broberg, Anders G.; Dyregrov, Atle; Lilled, Lars

    2005-01-01

    Background: On October 29, 1998, around 400 young people were gathered in an old warehouse in Goteborg, Sweden, for a discotheque party. A fire erupted and spread explosively. Adolescents were exposed to dreadful scenes inside and outside the building. In all, 63 young people were killed and 213 physically injured. An 18-month follow-up with 275

  10. Perceptions and Use of Language Learning Strategies among ESL Teachers and ELLs

    Science.gov (United States)

    Ardasheva, Yuliya; Tretter, Thomas R.

    2012-01-01

    This survey study explored perceptions and use of language learning strategies among English as a second language teachers and English-learning students (Grades 3-8, 10, and 11). The sample comprised 1,057 students (651 elementary, 275 middle, and 131 high school) and 54 teachers (31 elementary, 11 middle, and 12 high school) from 38 schools…

  11. File list: ALL.Neu.50.AllAg.Neurospheres [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Neu.50.AllAg.Neurospheres mm9 All antigens Neural Neurospheres SRX275807,SRX275...808,SRX275810,SRX275812,SRX275809,SRX275811 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Neu.50.AllAg.Neurospheres.bed ...

  12. File list: ALL.Neu.10.AllAg.Neurospheres [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Neu.10.AllAg.Neurospheres mm9 All antigens Neural Neurospheres SRX275807,SRX275...808,SRX275810,SRX275812,SRX275809,SRX275811 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Neu.10.AllAg.Neurospheres.bed ...

  13. File list: ALL.Neu.20.AllAg.Neurospheres [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Neu.20.AllAg.Neurospheres mm9 All antigens Neural Neurospheres SRX275807,SRX275...808,SRX275810,SRX275812,SRX275809,SRX275811 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Neu.20.AllAg.Neurospheres.bed ...

  14. File list: ALL.Neu.05.AllAg.Neurospheres [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Neu.05.AllAg.Neurospheres mm9 All antigens Neural Neurospheres SRX275807,SRX275...808,SRX275810,SRX275812,SRX275811,SRX275809 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Neu.05.AllAg.Neurospheres.bed ...

  15. Additive Effectiveness Investigations in Alternative Fuels

    Science.gov (United States)

    2014-05-01

    coupon, in a tube in shell heat exchanger. The fuel flows in the annulus and deposit forms on the outside. When a test temperature is specified, 275 °C...has a small filter made from materials similar to those found in aviation filter separators. The rating is a form of turbidity measurement with 100

  16. Exposure of pregnant mice to carbon black by intratracheal instillation

    DEFF Research Database (Denmark)

    Jackson, Petra; Hougaard, Karin S.; Vogel, Ulla;

    2011-01-01

    -induced response, such as inflammation during gestation, leads to secondary effects in the fetus. Time-mated C57BL/6BomTac mice were exposed by intratracheal instillation to vehicle (Nanopure water) or one of three concentrations (2.75, 13.5 or 67μg in 40μl Nanopure water) of carbon black Printex 90 (CB...

  17. FIS STUDY FOR CLARION COUNTY, PA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — This is a revised preliminary to case 11-03-1438S, adding 11.3 miles of new Zone AE study on Allegheny River and updating a 2.75 mile Zone AE detailed study on...

  18. Recent Developments in the Dutch Cervical Cancer Screening Programme

    NARCIS (Netherlands)

    M. Rebolj (Matejka)

    2008-01-01

    textabstractWorldwide, cervical cancer is the second most common female malignancy, diagnosed in 500,000 women each year, while 275,000 die from it. Without prevention, the peak incidence occurs at a relatively young age, between 40-55 years, when women are still active on the labour market and have

  19. Take One for the Team? Influence of Team and Individual Sport Participation on High School Athlete Substance Use Patterns

    Science.gov (United States)

    Kulesza, Magdalena; Grossbard, Joel R.; Kilmer, Jason; Copeland, Amy L.; Larimer, Mary E.

    2014-01-01

    The current Web-based survey investigated the association between team or individual sport participation (or both) and self-reported alcohol and tobacco use among high school athletes (N = 1,275) transitioning to college. Peak blood alcohol concentration, weekly drinking, and alcohol-related problems were significantly lower among athletes in…

  20. Asthma attacks with eosinophilia predict mortality from chronic obstructive pulmonary disease in a general population sample

    NARCIS (Netherlands)

    Hospers, JJ; Schouten, JP; Weiss, ST; Rijcken, B; Postma, DS

    1999-01-01

    We studied the association between allergy defined as eosinophilia (greater than or equal to 275 cells/mm(3)) and/or positive skin tests (sum score greater than or equal to 3) and mortality from chronic obstructive pulmonary disease (COPD) after adjustment for major risk factors. In addition, we inv

  1. Non-equilibrium Numerical Model of Homogeneous Condensation in Argon and Water Vapor Expansions

    Science.gov (United States)

    2010-02-05

    deficiencies, the steady state CNT nucleation rate with a correction10 is 2 used in such commercial fluid dynamics codes as GASP or CFD -particle. Unlike CNT...Phys. Chem. 92, 1023 (1988). 77U. Buck and H. Meyer, Surf . Sci. 156, 275 (1985). 78P. Lohbrandt, R. Galonska, H. J. Kim, M. Schmidt, C. Lauen- stein

  2. Invasive Infections with Multidrug-Resistant Yeast Candida auris, Colombia

    Science.gov (United States)

    Morales-López, Soraya E.; Parra-Giraldo, Claudia M.; Ceballos-Garzón, Andrés; Martínez, Heidys P.; Rodríguez, Gerson J.; Álvarez-Moreno, Carlos A.

    2017-01-01

    Candida auris is an emerging multidrug-resistant fungus that causes a wide range of symptoms. We report finding 17 cases of C. auris infection that were originally misclassified but correctly identified 27.5 days later on average. Patients with a delayed diagnosis of C. auris had a 30-day mortality rate of 35.2%. PMID:27983941

  3. Understanding, scoping and defining user experience: A survey approach

    NARCIS (Netherlands)

    Law, E.L.C.; Roto, V.; Hassenzahl, M.; Vermeeren, A.P.O.S.; Kort, J.

    2009-01-01

    Despite the growing interest in user experience (UX), it has been hard to gain a common agreement on the nature and scope of UX. In this paper, we report a survey that gathered the views on UX of 275 researchers and practitioners from academia and industry. Most respondents agree that UX is dynamic,

  4. Drug: D00817 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available NO. HCl 275.0844 276.2021 D00817.gif Antidepressant ATC code: N06AX12 dopamine noradrenalin selective reupta...ANTIDEPRESSANTS N06AX Other antidepressants N06AX12 Bupropion D00817 Bupropion hydrochloride (JAN/USP) USP d...ropion D00817 Bupropion hydrochloride (JAN/USP) Antidepressants Antidepressants,

  5. Can a school physical activity intervention improve physical self-perception and enjoyment?

    DEFF Research Database (Denmark)

    Lund-Cramer, Pernille; Christiansen, Lars Breum Skov; Smedegaard, Søren;

    2016-01-01

    -perception, and HRQoL) was collected prior to intervention and after 9 months. Results At baseline 2.892 children (92%) completed the survey. Mean physical self-perceptions [1-4] were generally high; Athletic Competence: 2.95, Body Attractiveness: 2.75, Physical Self-Worth: 3.12. However, a large minority had low self...

  6. Twin Screw Extrusion of DDGS-based Aquaculture Feeds

    Science.gov (United States)

    Six isocaloric (3.65 kilocalories/gram; kcal/g), isonitrogenous (35% dry-basis; db protein), ingredient blends were prepared with 0, 17.5, 20, 22.5, 25, and 27.5% DDGS and other ingredients (soybean meal, corn, fish meal, whey, soybean oil, vitamin and mineral mix). The blends were moisture balanced...

  7. 41 CFR 101-27.504 - Notice to GSA.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Notice to GSA. 101-27.504 Section 101-27.504 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 27-INVENTORY MANAGEMENT 27.5-Return of...

  8. Antibodies to immunoglobulin-G in dog sera, synovial fluids and aqueous humor : a comparative study of rheumatoid factor assays, suitable for routine application

    NARCIS (Netherlands)

    Bernadina, W.E.; Kol, P.J. van; Willemse, A.

    1988-01-01

    The incidence of anti-IgG antibodies (rheumatoid factors, RF) in body fluids (sera, synovial fluids and aqueous humor) selected from 62 normal and 275 diseased dogs was studied. Fluids were assayed by canine versions of standard agglutinating and/or precipitating RF assays with routine application i

  9. 78 FR 35087 - Office of Commercial Space Transportation; Notice of Extension of Comment Period for the Draft...

    Science.gov (United States)

    2013-06-11

    ... Ms. Stacey M. Zee, FAA Environmental Specialist, SpaceX EIS c/o Cardno TEC Inc., 275 West Street... Brownsville, Oliveira Library, 80 Fort Brown St. FOR FURTHER INFORMATION CONTACT: Ms. Stacey M. Zee..., Washington, DC 20591; email Stacey.Zee@faa.gov ; or phone (202) 267-9305. Issued in Washington, DC on: May...

  10. African Security Challenges: Now and Over the Horizon. Refugees, Internally-Displaced Persons, and Militancy in Africa: Current and/or Future Threat?

    Science.gov (United States)

    2010-01-01

    Aristide R., Astri Suhrke, and Sergio Aguayo , Escape from Violence (Oxford: Oxford University Press, 1989), p.275. 35 This is not to say that the... Sergio Aguayo , Escape from Violence (Oxford: Oxford University Press, 1989); Terry, Fiona. Condemned to Repeat: The Paradox of Humanitarian Action

  11. Pion-pion correlations at low relative momentum produced in [ital p]-[ital p] collisions at 27. 5 GeV/[ital c

    Energy Technology Data Exchange (ETDEWEB)

    Uribe, J.; Hartouni, E.P.; Jensen, D.A.; Kreisler, M.N. (Department of Physics and Astronomy, University of Massachusetts, Amherst, Massachusetts 01003 (United States)); Church, M.D.; Gottschalk, E.E.; Knapp, B.C.; Sippach, W.; Stern, B.J.; Wiencke, L.R. (Columbia University, Nevis Laboratories, Irvington, New York 10533 (United States)); Christian, D.C.; Gutierrez, G.; Holmes, S.D.; Wehmann, A. (Fermilab, Batavia, Illinois 60510 (United States)); Avilez, C. (Instituto de Fisica, Universidad de Guanajuato, Leon, Gto. (Mexico)); Forbush, M.; Huson, F.R.; White, J.T. (Department of Physics, Texas A M University, College Station, Texas 77843 (United States))

    1994-05-01

    We have measured the momentum correlation of pion pairs produced in the collisions of 27.5 GeV/[ital c] protons in liquid hydrogen. By considering events for which all final state particles have been measured, we have succeeded in reducing backgrounds due to particle misidentification below 5% for [pi][sup +] and 1% for [pi][sup [minus

  12. 76 FR 627 - Medicare Program; End-Stage Renal Disease Quality Incentive Program

    Science.gov (United States)

    2011-01-05

    ... Patients and Providers Act of 2008 (Pub. L. 110-275) NQF National Quality Forum PPS Prospective payment... the ``ESRD PPS final rule''), which appeared in the Federal Register on August 12, 2010 (75 FR 49030... PPS final rule the following three measures for the initial year of the ESRD QIP: Percentage...

  13. Memory Awareness for Faces in Individuals with Autism

    Science.gov (United States)

    Wilkinson, Desiree A.; Best, Catherine A.; Minshew, Nancy J.; Strauss, Mark S.

    2010-01-01

    Little is known regarding metacognition in individuals with autism. Specifically, it is unclear how individuals with autism think about their own mental states. The current study assessed memory awareness during a facial recognition task. High-functioning children (M = 13.1 years, n = 18) and adults (M = 27.5 years, n = 16) with autism matched…

  14. Lateral Reaction Jet Flow Interaction Effects on a Generic Fin-Stabilized Munition in Supersonic Crossflows

    Science.gov (United States)

    2013-11-01

    269–275. 9. Stahl, B.; Edmunds , H.; Gulhan, A. Experimental Investigation of Hot and Cold Side Jet Interaction With a Supersonic Cross Flow...LICHTENBERG-SCANLAN G MALEJKO T RECCHIA C STOUT W TOLEDO J TRAVAILLE E VAZQUEZ C WILSON 4 PM CAS (PDF) M BURKE R KIEBLER

  15. Experimental and Theoretical Investigation of Surface Chemistry Induced by Direct and Indirect Electronic Excitation

    Science.gov (United States)

    1993-07-01

    correlation between substrate absorption and the wavelength dependance of photodissociation or photodesorption was found. he lack of substrate involvement...0.8x10Ŗ cmŖ for 257, 275, 302 and 351 nm radiation respectively. We find no correlation between substrate absorption and the wavelength dependance of

  16. 76 FR 31547 - Medicare Program; Proposed Changes to the Electronic Prescribing (eRx) Incentive Program

    Science.gov (United States)

    2011-06-01

    ... Law 110-275, authorized the Secretary to establish a program to encourage the adoption and use of eRx... programs, and to encourage adoption of certified EHR technology. Accordingly, we are proposing changes to... hardship exemption requests using a Web-based tool or interface. However, our ability to receive...

  17. 77 FR 41899 - Indirect Food Additives: Polymers

    Science.gov (United States)

    2012-07-17

    ... Safety and Applied Nutrition (HFS-275), Food and Drug Administration, 5100 Paint Branch Pkwy., College.... Evaluation of Abandonment Under section 409(i) of the Federal Food, Drug, and Cosmetic Act (the FD&C Act) (21... the Center for Food Safety and Applied Nutrition by appointment with the information contact...

  18. 77 FR 9608 - American Chemistry Council; Filing of Food Additive Petition

    Science.gov (United States)

    2012-02-17

    ... CONTACT: Vanee Komolprasert, Center for Food Safety and Applied Nutrition (HFS-275), Food and Drug.... Background Under section 409(b)(5) of the Federal Food, Drug, and Cosmetic Act (the FD&C Act) (21 U.S.C. 348..., Center for Food Safety and Applied Nutrition. BILLING CODE 4160-01-P...

  19. Thyroid and parathyroid gland

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    2008399 Epidemiologic study of hypothyroidism in Jiangsu province. DUAN Yu(段宇), et al. Dept Endocrinol, 1st Affili Hosp, Nanjing Med Univ, Nanjing 210029. Chin J Endocrinol Metab 2008;24(3):275-277. Objective To investigate the prevalence and epidemiologic characteristics of hypothyroidism among community population in Jiangsu province.

  20. First results of ISO-SWS observations of Jupiter

    NARCIS (Netherlands)

    Encrenaz, T.; de Graauw, T.; Schaeidt, S.; Lellouch, E.; Feuchtgruber, H.; Beintema, D. A.; Bezard, B.; Drossart, P.; Griffin, M.; Heras, A.; Kessler, M.; Leech, K.; Morris, P.; Roelfsema, P. R.; Roos-Serote, M.; Salama, A.; Vandenbussche, B.; Valentijn, E. A.; Davis, G. R.; Naylor, D. A.

    1996-01-01

    The spectrum of Jupiter has been recorded between 2.75 and 14.5 mu m with the grating mode of the Short-Wavelength Spectrometer (SWS) of ISO. The resolving power is 1500. The main preliminary results of this observation are (1) at 3 mu m, the first spectroscopic signature, probably associated with N

  1. The Role of the Omental Microenvironment in Ovarian Cancer Metastatic Colonization

    Science.gov (United States)

    2012-08-01

    allowed us to rule out a requirement for B cells, T cells, or NK cells for ovarian cancer cell lodging within milky spots, confirming and expanding...Anatomy, embryology , and surgical applications. Surg Clin North Am 2000, 80:275–93–xii. 9. Collins D, Hogan AM, O’Shea D, Winter DC: The omentum

  2. Bibliography: The Mexican American in the Migrant Labor Setting.

    Science.gov (United States)

    Strange, Susan; Priest, Rhea Pendergrass

    The bibliography presents 275 citations (some with annotations) dealing with Mexican Americans in a migrant labor setting. Dates of the bibliographic entries range from 1928 to 1967. Materials are grouped under 9 subject categories. These include cultural characteristics, education, employment, health, migrant farm labor, minorities (minority…

  3. Data of evolutionary structure change: 1ACMC-3GD5C [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACMC-3GD5C 1ACM 3GD5 C C ANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELL...KHKVIASCFFEASTATRLSFQTSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQQTEGRLDNLHVAMVGD...EEYAHYAG-IPVINALTD-HEHPCQVVADLLTIRENFGRLAGLKLAYVGDG--NNVAHSLLLGCAKV-GMSIAVATPEGFTPDPAVSARASEIAGRTGAEVQIL--RD...4 ALA CA 275 THR CA 231 3GD5 C 3GD5C CLPAHRGEEI

  4. Data of evolutionary structure change: 1Q95E-3GD5E [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1Q95E-3GD5E 1Q95 3GD5 E E ANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELL...KHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGD...TELEEYAHYAG-IPVINALTD-HEHPCQVVADLLTIRENFGRLAGLKLAYVGDG--NNVAHSLLLGCAKVG-MSIAVATPEGFTPDPAVSARASEIAGRTGAEVQIL-...line> ILE CA 374 ALA CA 275 THR CA 238 3GD...5 E 3GD5E

  5. A Proof of Concept Imaging System for Automated Cervical Cancer Screening in Peru

    Science.gov (United States)

    Raza Garcia, Mabel Karel

    2013-01-01

    Cervical cancer is the second most frequent cancer in women around the world and affects half a million women per year. The World Health Organization (WHO) estimates that 275,000 women die every year, and 80% to 85% of these deaths occur in low-resource countries in Africa and South America. In Peru, cervical cancer has the highest incidence and…

  6. Model for Characterizing and Creating Certificate Programs in Technology-Specific Areas,

    Science.gov (United States)

    1996-05-01

    the TOEFL for applicants whose first language is not English. • GRE general and subject test. • Demonstrated competency in <prerequisites for...least 2.75 • English competency as demonstrated by TOEFL • Competence in data structures • Introductory level course in software engineering Course

  7. Why Women Choose Information Technology Careers: Educational, Social, and Familial Influences.

    Science.gov (United States)

    Turner, Sandra V.; Bernt, Phyllis W.; Pecora, Norma

    The educational, social, and familial influences that lead women to choose information technology (IT) careers were examined in an online survey. Of the 2,500 women who were employed in IT careers in 38 countries and who belonged to the IT professional organization, Systers, 275 responded to the online survey (11% response rate). The respondents…

  8. Gclust Server: 70170 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 70170 ATH_AT2G27470_15225884 Cluster Sequences - 275 CCAAT-box binding transcriptio...n factor subunit HAP3-related 1 1.00e+00 14.29 0.0 0.0 0.0 0.0 0.0 Show 70170 Cluster ID 70170 Sequence ID ATH_AT2G27470

  9. QTL Information Table: 851 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available D.Y., Chen, R.S., Zhai, W.X., and Zhu, L.H. (2006). Testifying the rice bacteria...ts homolog TFIIAgamma1. Mol Genet Genomics 275, 354-366. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16614777 ...

  10. Deep Hubble Space Telescope imaging of Sextans A. III. The star formation history

    NARCIS (Netherlands)

    Dolphin, AE; Saha, A; Skillman, ED; Dohm-Palmer, RC; Tolstoy, E; Cole, AA; Gallagher, JS; Hoessel, JG; Mateo, M

    2003-01-01

    We present a measurement of the star formation history of Sextans A, based on WFPC2 photometry that is 50% complete to V = 27.5 (M-V similar to +1.9) and I = 27.0. The star formation history and chemical enrichment history have been measured through modeling of the color-magnitude diagram (CMD). We

  11. Predictive Service Life Tests for Roofing Membranes: Phase 1

    Science.gov (United States)

    1993-12-01

    April 1991), pp 37-38, 40, 42, 44, 46. Puterman . M., K.H. Reinhorn, and M. Marton, "Specifications for Quality Assurance of Single-Ply Membrane...Material." Third International Symposium on Roofing Technology (NRCA, 1991), pp 271-275. Puterman , M., I. Soroka, and A. Bentur, "Deterioration of

  12. Influence of a constant magnetic field on thrombocytes. [delay of blood coagulation time

    Science.gov (United States)

    Meyerova, Y. A.

    1974-01-01

    In an experiment on white mice it was found that a constant electromagnetic field with strength of 250-275 oersteds is biologically active at an exposure of 55 minutes. Qualitative and morphological changes in thrombocytes 1-3 days following exposure reduced their numbers, prolonged blood coagulation time and increased the number of leucocytes.

  13. Characterization of pectate lyase A from Aspergillus niger

    NARCIS (Netherlands)

    Benen, J.A.E.; Parenicova, L.; Kester, H.C.M.; Visser, J.

    2001-01-01

    The Aspergillus niger plyA gene encoding pectate lyase A (EC 4.2.99.3) was cloned from a chromosomal EMBL4 library using the Aspergillus nidulans pectate lyase encoding gene [Dean, R. A., and Timberlake, W. E. (1989) Plant Cell 1, 275-284] as a probe. The plyA gene was overexpressed using a promoter

  14. VizieR Online Data Catalog: S4G galaxy morphologies in the CVRHS system (Buta+, 2015)

    Science.gov (United States)

    Buta, R. J.; Sheth, K.; Athanassoula, E.; Bosma, A.; Knapen, J. H.; Laurikainen, E.; Salo, H.; Elmegreen, D.; Ho, L. C.; Zaritsky, D.; Courtois, H.; Hinz, J. L.; Munoz-Mateos, J.-C.; Kim, T.; Regan, M. W.; Gadotti, D. A.; Gil de, Paz A.; Laine, J.; Menendez-Delmestre, K.; Comeron, S.; Erroz-Ferrer, S.; Seibert, M.; Mizusawa, T.; Holwerda, B.; Madore, B. F.

    2015-05-01

    Our final list has 2412 galaxies, 60 more than the extended S4system is a modified version of the de Vaucouleurs (1959HDP....53..275D) revised Hubble-Sandage (VRHS) system that is described in the de Vaucouleurs Atlas of Galaxies (dVA, Buta et al. 2007dvag.book.....B). (4 data files).

  15. Review of the Relationship between the College Students' Attitudes towards Love and Depression Levels

    Science.gov (United States)

    Sirin, Ahmet; Dashdamirov, Elshad; Ummet, Durmus

    2015-01-01

    This study aims to review the relation between college students' love attitudes and depression levels. Subjects selected were 125 male and 275 female bachelor's and master's degree students; a total of 400 students from various universities in Istanbul in academic year 2013-2014. Data for this study were collected employing both the Love Attitudes…

  16. Drug: D04857 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04857 Mixture, Drug Zinc oxide - eugenol mixt; Neodyne (TN) Zinc oxide [DR:D01170]...s affecting individual organs 27 Dental preparations 275 Pulp capping agents 2750 Pulp capping agents D04857 Zinc oxide - eugenol mixt PubChem: 17398198 ...

  17. 20.11.Symptom,sign and syndrome

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920196 The test combining brainstemevoked potentials (BAEP) with electrococh-leogram (Ecoch G).PAN Yingfu (潘映福),et al.Dept Neurol.Beijing Friendship Hosp.BeijingMed J 1991; 13 (5): 275-277.Twenty two patients,divided into 4 groups(deafness and tinnitus,vertigo brainstem and

  18. 78 FR 53763 - Proposed Collection; 60-day Comment Request Cancer Trials Support Unit (CTSU) (NCI)

    Science.gov (United States)

    2013-08-30

    ......... Health Care 75 12 10/60 150 Practitioner. CTSU Web Site Customer Health Care 275 1 15/60 69 Satisfaction Survey. Practitioner. CTSU Helpdesk Customer Health Care 325 1 15/60 81 Satisfaction Survey. Practitioner. CTSU OPEN Survey Health Care 60 1 15/60 15 Practitioner. PIO Customer Satisfaction Health Care 100 1...

  19. 78 FR 69428 - Submission for OMB Review; 30-Day Comment Request: Cancer Trials Support Unit (CTSU) (NCI)

    Science.gov (United States)

    2013-11-19

    ......... Health Care 75 12 10/60 150 Practitioner. CTSU Web Site Customer Health Care 275 1 15/60 69 Satisfaction Survey. Practitioner. CTSU Helpdesk Customer Health Care 325 1 15/60 81 Satisfaction Survey. Practitioner. CTSU OPEN Survey Health Care 60 1 15/60 15 Practitioner. PIO Customer Satisfaction Health Care 100 1...

  20. Improved renal function after early conversion from a calcineurin inhibitor to everolimus

    DEFF Research Database (Denmark)

    Mjörnstedt, L; Sørensen, S S; von Zur Mühlen, B;

    2012-01-01

    .2) mL/min with everolimus versus a decrease of 0.4 (12.0) mL/min in controls (p biopsy-proven acute rejection (BPAR) was 27.5% (n = 28) with everolimus and 11.0% (n = 11) in controls (p = 0.004). All...

  1. Domain Modeling: NP_003932.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_003932.3 chr7 Solution Structure of the GTPase Binding Domain of WASP in Complex with EspFU, an EHEC Effe...ctor p2k42a_ chr7/NP_003932.3/NP_003932.3_apo_204-275.pdb blast 0 ...

  2. Techniques for the Design and Implementation of Highly Reliable Multi- Processing Systems

    Science.gov (United States)

    1991-07-01

    Lecture Notes in Computer Science . Number... Lecture Notes in Computer Science , No. 275, Proceedings of the CRAI Consorzio per le Ricerche e le Applicazioni di Informatica Workshop on Software...and Languages Europe. Volume 365 of Lecture Notes in Computer Science , Springer-Verlag, New York, June 1989. [24] D. S. Rosenblum. Design

  3. Shape manipulation of ion irradiated Ag nanoparticles embedded in lithium niobate

    NARCIS (Netherlands)

    Wolf, S.; Rensberg, J.; Johannes, A.; Thomae, R.; Smit, F.; Neveling, R.; Moodley, M.; Bierschenk, T.; Rodriquez, M.; Afra, B.; Hasan, S.B.; Rockstuhl, C.; Ridgway, M.; Bharuth-Ram, K.; Ronning, C.

    2016-01-01

    Spherical silver nanoparticles were prepared by means of ion beam synthesis in lithium niobate. The embedded nanoparticles were then irradiated with energetic 84Kr and 197Au ions, resulting in different electronic energy losses between 8.1 and 27.5 keV nm−1 in the top layer of the samples. Due to th

  4. 76 FR 2863 - Endangered and Threatened Wildlife and Plants; Designation of Critical Habitat for the Sonoma...

    Science.gov (United States)

    2011-01-18

    ... effect'' area in Enclosure 1 (California Department of Fish and Game 2008) of the ``Programmatic... with fewer than 500 employees, wholesale trade entities with fewer than 100 employees, retail and... with less than $27.5 million in annual business, special trade contractors doing less than...

  5. Variations in concentrations and fluxes of dimethylsulfide (DMS) from the Indian estuaries

    Digital Repository Service at National Institute of Oceanography (India)

    Viswanadham, R.; Bharathi, M.D.; Sarma, V.V.S.S.

    . Biogeochemistry 83: 245-275. Suzuki, R., and T. Ishimaru. 1990. An improved method for the determination of phytoplankton chlorophyll using N,N-dimethylformamide. Journal of Oceanography 46: 190-194. Turner, S.M., G. Malin, P. Liss, D.S. Harbour, and P...

  6. Life history and population dynamics of an estuarine amphipod, Eriopisa chilkensis Chilton (Gammaridae)

    Digital Repository Service at National Institute of Oceanography (India)

    Aravind, N.P.; Sheeba, P.; Nair, K.K.C.; Achuthankutty, C.T.

    in fish culture. Eriopisa chilkensis can withstand wide variations in salinity (5-35) and temperature (27.5 - 34 degrees C) of the medium. It was cultured in un-aerated finger bowls using dried algal matter (Chara sp.) as food. The life span of females...

  7. Domain Modeling: NP_115859.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_115859.2 chr6 SOLUTION NMR STRUCTURE OF LINKED CELL ATTACHMENT MODULES OF MOUSE ...FIBRONECTIN CONTAINING THE RGD AND SYNERGY REGIONS, 10 STRUCTURES c2mfna_ chr6/NP_115859.2/NP_115859.2_apo_275-448.pdb blast 0 ...

  8. File list: Oth.Oth.10.AllAg.Thymus [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Oth.10.AllAg.Thymus mm9 TFs and others Others Thymus SRX107342,SRX107343,SRX275...397,SRX143826,SRX389596,SRX109320,SRX107341,SRX107339 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/Oth.Oth.10.AllAg.Thymus.bed ...

  9. FiveS rRNA sequences and fatty acid profiles of colourless sulfur-oxidising bacteria

    Digital Repository Service at National Institute of Oceanography (India)

    LokaBharathi, P.A.; Ortiz-conde, B.A.; Nair, S.; Chandramohan, D.; Colwell, R.R.

    was Pediococcus halophlus with an E.D. of 27.5 with very little similarity. Visual comparison of 5S rRNA sequences with other G-ve organisms that were intuitively chosen for their relatedness showed that both these isolates have the greatest homology (82...

  10. Assessment of shale-oil resources of the Central Sumatra Basin, Indonesia, 2015

    Science.gov (United States)

    Schenk, Christopher J.; Charpentier, Ronald R.; Klett, Timothy R.; Tennyson, Marilyn E.; Mercier, Tracey J.; Brownfield, Michael E.; Pitman, Janet K.; Gaswirth, Stephanie B.; Leathers-Miller, Heidi M.

    2015-11-12

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated means of 459 million barrels of shale oil, 275 billion cubic feet of associated gas, and 23 million barrels of natural gas liquids in the Central Sumatra Basin, Indonesia.

  11. Finding Edges and Lines in Images.

    Science.gov (United States)

    1983-06-01

    Artificial Intelligence Laboratory, Cambridge Mass., Al Memo 183, 1970. lildreth E. C. "Implementation of a Theory of Edge Detection ," M.I.T...1970. Marr D. C. "Early Processing of Visual Information," Phil. Trans. R. Soc. Lond. B 275 (1976), 483-524. Marr D. C. and Hildreth E. " Theory of Edge Detection ," Proc

  12. Decreasing serial cost sharing

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Østerdal, Lars Peter Raahave

    2009-01-01

    The increasing serial cost sharing rule of Moulin and Shenker (Econometrica 60:1009-1037, 1992) and the decreasing serial rule of de Frutos (J Econ Theory 79:245-275, 1998) are known by their intuitive appeal and striking incentive properties. An axiomatic characterization of the increasing serial...

  13. Assessment of the Molecular Classfication of Diffuse Large B-Cell Lymphoma by Immunohistochemistry Using A Tissue Microarray%组织芯片免疫组化法确定弥漫大B细胞性淋巴瘤的分子分型的评价

    Institute of Scientific and Technical Information of China (English)

    刘艳辉; 董秋美

    2007-01-01

    @@ 1 文献类型 预后. 2 证据水平 2b. 3 文献来源 Hans CP, Weisenburger DD, Greiner TC, et al. Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray [J]. Blood, 2004,1 (103) :275-281.

  14. Data of evolutionary structure change: 1FGQA-2IUKB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1FGQA-2IUKB 1FGQ 2IUK A B -HKIKGTVVLMPKNELNL-----------NAFLGRSVSL...line>PHE CA 468 2IUK B 2IUK...> SER CA 225 THR CA 303 PRO CA 275 2IUK... B 2IUKB KSAIFQLRVTS GLU CA 493 PHE CA 555 2IUK

  15. Dicty_cDB: AFM791 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ts) Value AB170103_1( AB170103 |pid:none) Macaca fascicularis brain cDNA clo... 246 e-130 EU684308_1( EU6843...08 |pid:none) Exorista civilis heat shock protei... 275 e-125 ( P36415 ) RecName: Full=Heat shock cognate 70

  16. Violent women : a multicentre study into gender differences in forensic psychiatric patients

    NARCIS (Netherlands)

    de Vogel, Vivienne; Stam, Jeantine; Bouman, Yvonne H. A.; Ter Horst, P.R.M.; Lancel, Marike

    2016-01-01

    To gain insight into the relatively small, but increasing group of women in forensic psychiatry, a retrospective multicentre study was started gathering information from the files of 275 female patients of four Dutch forensic psychiatric hospitals on characteristics and violence risk factors. Overal

  17. PEOPLE & POINTS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    “U.S. traders are wise and we have no grounds for suspicion.”Chinese Minister of Commerce Bo Xilai,criticizing some U.S. lawmakers’ proposal for a 27.5 percent increase in import tariff on Chinese goods at a March 12 press conference in Beijing “Serving

  18. Does the expansion of a motorway network lead to economic agglomeration? : Evidence from China

    NARCIS (Netherlands)

    Yu, Nannan; de Roo, Gert; de Jong, Martin; Storm, Servaas

    2016-01-01

    In contrast to most existing studies examining the generative effects of transport infrastructure, this paper addresses the distributive effects of transport infrastructure in China. Using panel data from 275 Chinese municipalities in the 2000–2010 period, our study explores the role of road infrast

  19. The Child's Status in the Democratic State

    Science.gov (United States)

    Schrag, Francis

    1975-01-01

    Examines and questions the child and universal adult suffrage, justifying the child's exclusion, establishing criteria for voter competence, evaluating the competence of children, and chronological age as a criterion. Journal available from Sage Publications, Inc., 275 South Beverly Drive, Beverly Hills, California 90212. (ND)

  20. Natural gas industry in Iran

    Energy Technology Data Exchange (ETDEWEB)

    Omidvar, Hedayat

    2010-09-15

    Iran holds the second largest gas reserves in the word with over 27.5 trillion cubic meters (TCM) of natural gas. Due to lack of geological surveys in certain geographical regions in Iran, it is likely to explore further reserves in the future.

  1. Compilation of 1990 Annual Reports of the Navy ELF Communications System Ecological Monitoring Program. Volume 3. Tabs G thru I.

    Science.gov (United States)

    1991-08-01

    plant cell wall ( Lehninger 1982). Enzymes used to break down leaves are named according to the structure on which they react; for example, cellulase...Freshwater Ecol., 5: 269-275. Lehninger , G. 1982. Principles of Biochemistry, p. 262. New York, Worth Publishers. g McArthur, J. V., LG. Left, D. A

  2. Organic carbon and iron modulate nitrification rates in mangrove swamps of Goa, south west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Krishnan, K.P.; LokaBharathi, P.A.

    , Publishers, San Diego, CA. 275p. Qasim, S.Z., Wafar, M.V.M.,1990. Marine resources in the tropics. Resource Management and Optimization 7,141–169. Rivera-Monroy, V.H., Day, J.D., Twilley, R.R., Vera-Herrera, F., Coronado-Molina 1995.Flux of nitrogen...

  3. Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene

    DEFF Research Database (Denmark)

    Jakkula, Eveliina; Leppä, Virpi; Sulonen, Anna-Maija;

    2010-01-01

    in 711 cases and 1029 controls from Finland, and the top two findings were validated in 3859 cases and 9110 controls from more heterogeneous populations. SNP (rs744166) within the STAT3 gene was associated to MS (p = 2.75 x 10(-10), OR 0.87, confidence interval 0.83-0.91). The protective haplotype for MS...

  4. 21.3.Other psychosis

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920199 Quantitative EEG analysis and itsvalue in differential diagnosis of depression:power spectrum and coherence analysis.LIUXiang (刘向),et al.Instit Merit Health,Beijing MedUniv,100083.Chin J Neurol & Psychiat 1991; 24(5): 275-277.Power spectrum and coherence analysis weretaken on 47 depressive patients and 43 normal

  5. 75 FR 1589 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-01-12

    ... been lowered, the reinterview rate has been increased and a new Census Coverage Measurement Recall Bias... Coverage Measurement, Person Interview, Person Interview Reinterview, and Recall Bias Panel Study. OMB.... Type of Request: New collection. Burden Hours: 68,938. Number of Respondents: 275,750. Average...

  6. Pepper yellow mosaic virus, a new potyvirus in sweet-pepper. Archives of Virology

    NARCIS (Netherlands)

    Inoue-Nagata, A.K.; Fonseca, M.E.N.; Resende, de R.O.; Boiteux, L.S.; Monte, D.C.; Dusi, A.N.; Ávila, de A.C.; Vlugt, van der R.A.A.

    2002-01-01

    A potyvirus was found causing yellow mosaic and veinal banding in sweetpepper in Central and Southeast Brazil. The sequence analysis of the 3' terminal region of the viral RNA revealed a coat protein of 278 amino acids, followed by 275 nucleotides in the 3'-untranslated region preceding a polyadenyl

  7. The Mediator Effect of Career Development between Personality Traits and Organizational Commitment: The Example of Sport Communication Technology Talents

    Science.gov (United States)

    Lo, Hung-Jen; Lin, Chun-Hung; Tung-Hsing, Lin; Tu, Peng-Fei

    2014-01-01

    This paper explored the relationships among career development, personality trait, and organizational commitment and examines whether career development mediates the relationship between personality trait and organizational commitment. The sample was 275 sport communication technology talents in Taiwan. The instrument included the Personality…

  8. FID detection of EPR and ENDOR spectra at high microwave frequencies.

    Science.gov (United States)

    Blok, H; Akimoto, I; Milikisyants, S; Gast, P; Groenen, E J J; Schmidt, J

    2009-11-01

    High-frequency pulsed EPR spectroscopy allows FID detection of EPR spectra owing to the short dead time that can be achieved. This FID detection is particularly attractive for EPR and ENDOR spectroscopy of paramagnetic species that exhibit inhomogeneously broadened EPR lines and short dephasing times. Experiments are reported for the metalloprotein azurin at 275 GHz.

  9. 76 FR 43923 - Final Flood Elevation Determinations

    Science.gov (United States)

    2011-07-22

    ... participation in the National Flood Insurance Program (NFIP). DATES: The date of issuance of the Flood Insurance Rate Map (FIRM) showing BFEs and modified BFEs for each community. This date may be obtained by... Approximately 275 feet downstream of Big Bethel +9 Road. Approximately 20 feet upstream of the confluence...

  10. Beliefs about Parental Authority Legitimacy among Refugee Youth in Jordan: Between- and Within-Person Variations

    Science.gov (United States)

    Smetana, Judith G.; Ahmad, Ikhlas; Wray-Lake, Laura

    2016-01-01

    We examined within- and between-person variations in parental legitimacy beliefs in a sample of 883 Arab refugee youth (M[subscript age] = 15.01 years, SD = 1.60), 277 Iraqis, 275 Syrians, and 331 Palestinians, in Amman, Jordan. Latent profile analyses of 22 belief items yielded 4 profiles of youth. The "normative" profile (67% of the…

  11. 75 FR 11940 - Office of the Chief Human Capital Officer; Information Collection; Ancestry and Ethnicity Data...

    Science.gov (United States)

    2010-03-12

    ... NATIONAL INTELLIGENCE Office of the Chief Human Capital Officer; Information Collection; Ancestry and... the Chief Human Capital Officer, ODNI, at Washington, DC 20511, or call 703-275-3369. Please cite... submitted on or before April 12, 2010. FOR FURTHER INFORMATION CONTACT: The Office of the Chief...

  12. Academic Expectations and Actual Achievements: The Roles of Hope and Effort

    Science.gov (United States)

    Levi, Uzi; Einav, Michal; Ziv, Orit; Raskind, Ilana; Margalit, Malka

    2014-01-01

    This study sought to extend the research on adolescents' hope, academic expectations, and average grades. The hope theory (Snyder, "Psychological Inquiry" 13(4):249-275, 2002), the salutogenic paradigm (with a focus on sense of coherence (SOC) (Antonovsky 1987)), and Bandura's ("Journal of Management" 38(1):9-44,…

  13. The Child with Arthritis in the School Setting

    Science.gov (United States)

    Sanzo, Maria

    2008-01-01

    Arthritis is a condition often associated with the elderly. However, arthritis affects approximately 275,000 children nationwide. Symptoms may vary from one swollen joint to multiply affected joints coupled with fatigue, fever, and rash. Its effect on the school-age child can range from missing a few days of school per year to hospitalizations…

  14. Factor Analysis of the Aberrant Behavior Checklist in Individuals with Autism Spectrum Disorders

    Science.gov (United States)

    Brinkley, Jason; Nations, Laura; Abramson, Ruth K.; Hall, Alicia; Wright, Harry H.; Gabriels, Robin; Gilbert, John R.; Pericak-Vance, Margaret A. O.; Cuccaro, Michael L.

    2007-01-01

    Exploratory factor analysis (varimax and promax rotations) of the aberrant behavior checklist-community version (ABC) in 275 individuals with Autism spectrum disorder (ASD) identified four- and five-factor solutions which accounted for greater than 70% of the variance. Confirmatory factor analysis (Lisrel 8.7) revealed indices of moderate fit for…

  15. Integrative prognostic risk score in acute myeloid leukemia with normal karyotype

    NARCIS (Netherlands)

    F. Damm (Frederik); M. Heuser (Michael); H.M. Morgan (Helen); K. Wagner (Katharina); K. Görlich (Kerstin); A. Großhennig (Anika); I. Hamwi (Iyas); F. Thol (Felicitas); E. Surdziel (Ewa); W. Fiedler (Walter); M. Lübbert (Michael); L. Kanz (Lothar); C. Reuter (Christoph); G. Heil (Gerhard); H.R. Delwel (Ruud); B. Löwenberg (Bob); P.J.M. Valk (Peter); J. Krauter; A. Ganser (Arnold)

    2011-01-01

    textabstractTo integrate available clinical and molecular information for cytogenetically normal acute myeloid leukemia (CN-AML) patients into one risk score, 275 CN-AML patients from multicenter treatment trials AML SHG Hannover 0199 and 0295 and 131 patients from HOVON/SAKK protocols as external c

  16. Micro-PROUST.

    Science.gov (United States)

    1985-06-01

    275. 4. Johnson, W.L., and Soloway, E. Intention-Based Diagnosis of Programming Errors. Proc. of the Nat. Conf. on Art . Intel., AAAI, 1984, pp. 162...CHAR 124.)) (INCF CNT)) ((AND (m LCHAR 124.)(a CHAR 35.)(- CNT 0)) (DECF CNT)))))) Used by the #+ and - sacros (DEFUN 1#-FEATUREPI (F) (COND ((ATOM F

  17. Eco-biology of marine diatoms with emphasis on the influence of physico-chemical parameters

    Digital Repository Service at National Institute of Oceanography (India)

    Mitbavkar, S.

    in the Dutch Wadden Sea. Nether J Sea Res 15: 196-216 Connor MS, Edgar RK (1982) Selective grazing by the mud snail Ilyanassa obsoleta. Oecologia 53: 271-275 Corpe WA (1970) Attachment of marine bacteria to solid surfaces. In: Manley RS (ed) Adhesions...

  18. Extending quantum efficiency roll-over threshold with compositionally graded InGaN/GaN LED

    KAUST Repository

    Mishra, Pawan

    2014-12-01

    We report a significant improvement in the electrical characteristic of compositionally graded InGaN/GaN multiple-quantum-well (MQWs) micro-LED. The efficiency droop in this device occurred at ∼20 times higher injection levels (∼275 A/cm2) compared to a conventional step-MQWs microLED (∼14 A/cm2).

  19. 78 FR 50026 - Basin Electric Power Cooperative, Inc.: Notice of Intent To Prepare a Supplemental Draft...

    Science.gov (United States)

    2013-08-16

    ..., operation and maintenance of approximately 275 ] miles of new 345-kV single pole transmission line... SDEIS will evaluate a new alternative for the transmission line. The SDEIS will address the construction...-kV single pole transmission line and double circuit 345/115-kV transmission lines, 5 new...

  20. 75 FR 1568 - Endangered and Threatened Wildlife and Plants; Proposed Designation of Critical Habitat for...

    Science.gov (United States)

    2010-01-12

    ... the level, design, or regulation of forecast economic activities. That is, the designation of critical..., productivity, jobs, the environment, or other units of the government. (b) Whether the rule will create... than $5 million in annual sales, general and heavy construction businesses with less than $27.5...

  1. Het effect van personalisatie en leeftijdscongruentie in narratieve communicatie op website satisfactie en recall van online gezondheidsinformatie

    NARCIS (Netherlands)

    Bol, N.; van Weert, J.; de Haes, H.; Loos, E.; Smets, E.

    2013-01-01

    The effect of personalization and age congruency on website satisfaction and recall of information was tested in a 2 (personalization: personalized vs. nonpersonalized video) × 2 (age congruency: congruent vs. incongruent) experimental design (n = 275). Personalization was found to be an effective c

  2. 76 FR 45697 - Vocational Rehabilitation and Employment Program-Changes to Subsistence Allowance

    Science.gov (United States)

    2011-08-01

    ... military to civilian careers. Because eligible veterans will begin to make the election on August 1, 2011... transition from military to civilian careers. Because eligible veterans will begin to make the election on...,252 2015 65,176 872.49 56,865 2016 65,829 889.94 58,584 5-Year Total 275,726 Accounting Statement...

  3. Professional Accounting Body Affiliation: Shifting Priorities in the Transition from Student to Practitioner

    Science.gov (United States)

    Sidaway, Shannon; de Lange, Paul; Bouilheres, Frederique; Sangster, Alan

    2013-01-01

    Extending the scope of prior research, this study examines perceptions of the costs and benefits of professional accounting body affiliation in the transition from student to practitioner. The study employs data obtained from 275 students and 508 practitioners and reports differences in respect of the importance placed on various costs and…

  4. Effectiveness of interventions influencing activities of daily living on visually impaired patients: a systematic review.

    NARCIS (Netherlands)

    Poot, E.; Mistiaen, P.; Hickox, S.; Wagner, C.

    2003-01-01

    Visually impaired patients have difficulty in performing the activities of daily living (ADL). For example, one study found that 21% of the participants had trouble with dressing or undressing, 25 % with mobility at home, and 31 % with eating and drinking. Another study showed that 27,5% experience

  5. Success with lean processing. An example with the type AM 105 selective-cut roadheading machine; Mit lean processing zum Erfolg. Ein Praxisbeispiel aus dem Streckenvortrieb

    Energy Technology Data Exchange (ETDEWEB)

    Tubbesing, W.; Jung, K. [Deutsche Steinkohle AG (DSK), Gelsenkirchen (Germany). Bergwerk Lippe; Forell, R. [Deutsche Steinkohle AG (DSK), Bottrop (Germany). Servicebereich Belegschaft

    2007-08-02

    A significant increase in the drivage rate in heading BP 275.1 was achieved at the Lippe colliery by effective application of lean processing. The drivage team was trained in this method in workshops and reduced the cycle times by more than 15% by standard working processes. Operating studies conducted in parallel accompanied the drivage and confirm the success. (orig.)

  6. Domain Modeling: NP_667338.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_667338.3 chr4 THE MODELED STRUCTURE OF FIBRITIN (GPWAC) OF BACTERIOPHAGE T4 BASED ON CRYO-EM RECONSTRUCTI...ON OF THE EXTENDED TAIL OF BACTERIOPHAGE T4 p2bsga_ chr4/NP_667338.3/NP_667338.3_apo_275-740.pdb swppa 0 ...

  7. Breaking the DNA damage response to improve cervical cancer treatment

    NARCIS (Netherlands)

    Wieringa, Hylke W.; van der Zee, Ate G. J.; Vries, de Elisabeth G. E.; van Vugt, Marcel A. T. M.

    2016-01-01

    Every year, cervical cancer affects similar to 500,000 women worldwide, and similar to 275,000 patients die of this disease. The addition of platin-based chemotherapy to primary radiotherapy has increased 5-year survival of advanced-stage cervical cancer patients, which is, however, still only 66%.

  8. Listado anotado de Solanum L. (Solanaceae) en el Perú

    DEFF Research Database (Denmark)

    Särkinen, Tiina; Baden, Maria; Gonzáles, Paúl

    2015-01-01

    The genus Solanum is among the most species-rich genera both of the Peruvian flora and of the tropical Andes in general. The present revised checklist treats 275 species of Solanum L., of which 252 are native, while 23 are introduced and/or cultivated. A total of 73 Solanum species (29% of native...

  9. Teaching Managerial Economics in MBA Programs: A Survey of AACSB Colleges

    Science.gov (United States)

    Kolluri, Bharat; Singamsett, Rao

    2007-01-01

    There is a significant variation in the managerial economics course in terms of the prerequisites, contents and delivery in the MBA programs of AACSB [Association to Advance Collegiate Schools of Business] institutions. In order to get detailed information on these aspects, we conducted a survey of 275 AACSB institutions and reported the results.…

  10. 40 CFR 721.10168 - Cesium tungsten oxide.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Cesium tungsten oxide. 721.10168... Substances § 721.10168 Cesium tungsten oxide. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified as cesium tungsten oxide (PMN P-08-275; CAS No....

  11. Deposition temperature effect on electrical properties and interface of high-k ZrO{sub 2} capacitor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Joo-Hyung; Ignatova, Velislava A [Fraunhofer Institute, Center of Nanoelectronic Technologies (CNT), Koenigsbruecker Str., 01099 Dresden (Germany); Heitmann, Johannes; Oberbeck, Lars [Qimonda Dresden GmbH and Co. OHG, Koenigsbruecker Str. 180, 01099 Dresden (Germany)], E-mail: joo-hyung.kim@inha.ac.kr

    2008-09-07

    The electrical characteristics, i.e. leakage current and capacitance, of ZrO{sub 2} based metal-insulator-metal structures, grown at 225, 250 and 275 deg, C by atomic layer deposition, were studied. The lowest leakage current was obtained at 250 deg. C deposition temperature, while the highest dielectric constant (k {approx} 43) was measured for the samples grown at 275 {sup 0}C, most probably due to the formation of tetragonal/cubic phases in the ZrO{sub 2} layer. We have shown that the main leakage current of these ZrO{sub 2} capacitors is governed by the Poole-Frenkel conduction mechanism. It was observed by x-ray photoelectron spectroscopy depth profiling that at 275 {sup 0}C deposition temperature the oxygen content at and beyond the ZrO{sub 2}/TiN interface is higher than at lower deposition temperatures, most probably due to oxygen inter-diffusion towards the electrode layer, forming a mixed TiN-TiO{sub x}N{sub y} interface layer. At and above 275 deg. C the ZrO{sub 2} layer changes its structure and becomes crystalline as proven by XRD analysis. (fast track communication)

  12. Silica extraction from geothermal water

    Science.gov (United States)

    Bourcier, William L; Bruton, Carol J

    2014-09-23

    A method of producing silica from geothermal fluid containing low concentration of the silica of less than 275 ppm includes the steps of treating the geothermal fluid containing the silica by reverse osmosis treatment thereby producing a concentrated fluid containing the silica, seasoning the concentrated fluid thereby producing a slurry having precipitated colloids containing the silica, and separating the silica from the slurry.

  13. 33 CFR 159.16 - Authorization to label devices.

    Science.gov (United States)

    2010-07-01

    ... accordance with the procedure in 46 CFR 2.75, may suspend, withdraw, or terminate any letter of authorization... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Authorization to label devices... (CONTINUED) POLLUTION MARINE SANITATION DEVICES Certification Procedures § 159.16 Authorization to...

  14. The meaning of Mindfulness in children and adolescents: Further validation of the Child and Adolescent Mindfulness Measure (CAMM) in two independent samples from The Netherlands

    NARCIS (Netherlands)

    E.I. de Bruin; B.J.H. Zijlstra; S.M. Bögels

    2013-01-01

    Factor structure, internal consistency, and construct validity of the Dutch version of the Child and Adolescent Mindfulness Measure (CAMM) were studied in two samples of school children and adolescents (n = 275, 10-12 years and n = 560, 13-16 years) from The Netherlands, using principle factor analy

  15. 76 FR 255 - Amendments To Form ADV; Extension of Compliance Date

    Science.gov (United States)

    2011-01-04

    ... COMMISSION 17 CFR Parts 275 and 279 RIN 3235-AI17 Amendments To Form ADV; Extension of Compliance Date AGENCY: Securities and Exchange Commission. ACTION: Final rule; extension of compliance date. SUMMARY: The Securities and Exchange Commission is extending the compliance date for Part 2B of Form ADV, the...

  16. Psychometric Properties of the Chinese Cultural Beliefs about Adversity Scale

    Science.gov (United States)

    Leung, Janet T. Y.; Shek, Daniel T. L.

    2013-01-01

    Objective: The purpose of the study was to examine the psychometric properties of the Chinese Cultural Beliefs about Adversity scale (CBA). Methods: The CBA was administered in a sample of 275 Chinese parents experiencing economic disadvantage. Results: The CBA was found to be internally consistent. Consistent with the conceptual framework, factor…

  17. Sleep EEG spectral analysis in a diurnal rodent : Eutamias sibiricus

    NARCIS (Netherlands)

    DIJK, DJ; DAAN, S

    1989-01-01

    1. Sleep was studied in the diurnal rodent Eutamias sibiricus, chronically implanted with EEG and EMG electrodes. Analysis of the distribution of wakefulness, nonrapid eye movement (NREM) sleep, and rapid eye movement (REM) sleep over the 24 h period (LD 12:12) showed that total sleep time was 27.5%

  18. Study of electronic prescribing rates and barriers identified among providers using electronic health records in New York City

    Directory of Open Access Journals (Sweden)

    Sam Amirfar

    2011-05-01

    Conclusions The data gathered from our providers indicate that there is an increasing trend in the eRx rate to 27.5% by July 2010, but still short of the 40% meaningful use level. However, obstacles to increased rates remain primarily providers' belief that many patients prefer paper prescriptions and many pharmacies are not yet prepared to accept electronic prescriptions.

  19. A transfer technique for high mobility graphene devices on commercially available hexagonal boron nitride

    NARCIS (Netherlands)

    Zomer, P. J.; Dash, S. P.; Tombros, N.; van Wees, B. J.

    2011-01-01

    We present electronic transport measurements of single and bilayer graphene on commercially available hexagonal boron nitride. We extract mobilities as high as 125 000 cm(2) V-1 s(-1) at room temperature and 275 000 cm(2) V-1 s(-1) at 4.2 K. The excellent quality is supported by the early developmen

  20. Analysis of Microtubule Mediated Functions of Prostate Specific Membrane Antigen

    Science.gov (United States)

    2006-04-01

    proteins. Proteins such as CD3-, LIMP-II, tyrosi- nase CD4, and GLUT4 have a [DE]XXXL type signal, whereas a DXXLL signal has been characterized in...PII and the insulin-sensitive glucose transporter GLUT4 . J. Biol. Chem. 275, 39874–39885. Sekiguchi, M., Okamoto, K., and Sakai, Y. (1989). Release of

  1. Wood preservation of low-temperature carbonisation

    NARCIS (Netherlands)

    Gosselink, R.J.A.; Krosse, A.M.A.; Putten, van der J.C.; Kolk, van der J.C.; Klerk-Engels, de B.; Dam, van J.E.G.

    2004-01-01

    Pine (Pinus sylvestris L.) wood with dimensions (100 x 10 x 10mm) was thermally treated at 275degreesC in a muffle oven to impart resistance to microbial degradation. Low-temperature carbonised pine resulted in a visually homogeneously treated product with a substantial (about 70% w/w) reduced non-c

  2. 21 CFR 177.2420 - Polyester resins, cross-linked.

    Science.gov (United States)

    2010-04-01

    .... Pentaerythritol. Polyoxypropylene ethers of 4,4′-isopropylide-nediphenol (containing an average of 2-7.5 moles of...-pentanediol. (3) Cross-linking agents: Butyl acrylate. Butyl methacrylate. Ethyl acrylate. Ethylhexyl acrylate... the production of the resins or added thereto to impart desired technical or physical...

  3. Domain Modeling: NP_068741.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_068741.1 chr6 Crystal structure of human Fanconi Anemia protein E C-terminal dom...ain p2ilra_ chr6/NP_068741.1/NP_068741.1_apo_275-535.pdb blast 276E,277S,278L,320S,321P,322S,323Q,325D,356S,

  4. Encyclopedia of new media an essential reference to communication and technology

    CERN Document Server

    Jones, Steve

    2002-01-01

    ""From Space Invaders to digital television, the 275 entries explore the developments of computer and Web applications and related media. Most take a historical perspective to innovation, but many explain such concepts as access, firewalls, information design, linking, markup languages and usability. . . . This informed and up-to-date guide to emerging technologies is highly recommended to academic and public libraries.""

  5. Computers, pattern, chaos and beauty

    CERN Document Server

    Pickover, Clifford A

    1980-01-01

    Combining fractal theory with computer art, this book introduces a creative use of computers. It describes graphic methods for detecting patterns in complicated data and illustrates simple techniques for visualizing chaotic behavior. ""Beautiful."" - Martin Gardner, Scientific American. Over 275 illustrations, 29 in color.

  6. AcEST: DK950159 [AcEST

    Lifescience Database Archive (English)

    Full Text Available _BOVIN PAX-interacting protein 1 OS=Bos taurus GN... 33 1.0 sp|Q8K4J0|DCR1C_MOUSE Protein artemis OS=Mus mus...: 275 AAAKRRLPPGKEPGLIN 291 >sp|Q8K4J0|DCR1C_MOUSE Protein artemis OS=Mus musculu

  7. File list: InP.Bld.05.AllAg.Leukemia,_Myeloid [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Bld.05.AllAg.Leukemia,_Myeloid mm9 Input control Blood Leukemia, Myeloid SRX275...704,SRX467481,SRX760026,SRX275706,SRX1527585,SRX1527584,SRX1527583,SRX760025 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/InP.Bld.05.AllAg.Leukemia,_Myeloid.bed ...

  8. Adult Attachment, Culturally Adjusted Attachment, and Interpersonal Difficulties of Taiwanese Adults

    Science.gov (United States)

    Wang, Chia-Chih DC; Scalise, Dominick A.

    2010-01-01

    This study examines the applicability of Western adult attachment perspectives to interpersonal difficulties experienced by individuals with indigenous Chinese cultural backgrounds. A total of 275 Taiwanese university students completed self-report surveys of adult attachment, ideal attachment, and interpersonal problems. Culturally adjusted…

  9. Compact Solid State Terahertz Detectors

    Science.gov (United States)

    2007-07-09

    Liu, C. Y. Song, and Z. R. Wasilewski , Appl. Phys. Lett. 86, 231103 (2005). [4] F.H. Pollak and H. Shen, Mater. Sci. Eng., R. 10, 275 (1993). [5...H. C. Liu, C. Y. Song, and Z. R. Wasilewski , Appl. Phys. Lett. 86, 231103 (2005). 3 Design of Be and Si δ-doped GaAs/AlAs quantum

  10. Gclust Server: 118187 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 118187 CRE_180514 Cluster Sequences Related Sequences(29) 275 no annotation 1 1.00e...-99 14.29 0.0 0.0 0.0 0.0 0.0 Show 118187 Cluster ID 118187 Sequence ID CRE_180514 Link to cluster sequences

  11. Role of the Chemokine MCP-1 in Sensitization of PKC-Medicated Apoptosis in Prostate Cancer Cells

    Science.gov (United States)

    2008-02-01

    prostate cancer cells. Lack of proteolytic cleavage of PKCδ. J. Biol. Chem. 275: 7574-7582 (2000). 5. Garcia -Bermejo, M.L., Leskow, F.C., Fujii, T., Wang...Q., Blumberg, P.M., Ohba, M., Kuroki, T., 5 Han, K.C., Lee, J., Marquez , V.E., and Kazanietz, M.G. Diacylglycerol (DAG)-lactones, a new class of

  12. Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Sarah L. [Univ. of California, Berkeley, CA (United States)

    2008-01-01

    Several reactions producing odd-Z transactinide compound nuclei were studiedwith the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus ator near the same excitation energy with similar values of angular momentum via differentnuclear reactions. In doing so, it can be determined if there is a preference in entrancechannel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's"Fusion By Diffusion" model is nearly identical forthe two reactions. Additionally, because the same compound nucleus is produced, theexit channel is the same. Four compound nuclei were examined in this study: 258Db, 262Bh, 266Mt, and 272Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: 50Ti + 209Bi vs. 51V + 208Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs' cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrancechannel in these paired reactions. Charge equilibration immediately prior to fusionleading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the 209Bi(52Cr,n) reaction. 260Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35$+19\\atop{-9}$ ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki

  13. Rodents and risk in the Mekong Delta of Vietnam: seroprevalence of selected zoonotic viruses in rodents and humans.

    Science.gov (United States)

    Van Cuong, Nguyen; Carrique-Mas, Juan; Vo Be, Hien; An, Nguyen Ngoc; Tue, Ngo Tri; Anh, Nguyet Lam; Anh, Pham Hong; Phuc, Nguyen The; Baker, Stephen; Voutilainen, Liina; Jääskeläinen, Anne; Huhtamo, Eili; Utriainen, Mira; Sironen, Tarja; Vaheri, Antti; Henttonen, Heikki; Vapalahti, Olli; Chaval, Yannick; Morand, Serge; Bryant, Juliet E

    2015-01-01

    In the Mekong Delta in southern Vietnam, rats are commonly traded in wet markets and sold live for food consumption. We investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. The indirect fluorescence antibody test (IFAT) was used to determine seropositivity to representative reference strains of hantaviruses (Dobrava virus [DOBV], Seoul virus [SEOV]), cowpox virus, arenaviruses (lymphocytic choriomeningitis virus [LCMV]), flaviviruses (tick-borne encephalitis virus [TBEV]), and rodent parechoviruses (Ljungan virus), using sera from 245 humans living in Dong Thap Province and 275 rodents representing the five common rodent species sold in wet markets and present in peridomestic and farm settings. Combined seropositivity to DOBV and SEOV among the rodents and humans was 6.9% (19/275) and 3.7% (9/245), respectively; 1.1% (3/275) and 4.5% (11/245) to cowpox virus; 5.4% (15/275) and 47.3% (116/245) for TBEV; and exposure to Ljungan virus was 18.8% (46/245) in humans, but 0% in rodents. Very little seroreactivity was observed to LCMV in either rodents (1/275, 0.4%) or humans (2/245, 0.8%). Molecular screening of rodent liver tissues using consensus primers for flaviviruses did not yield any amplicons, whereas molecular screening of rodent lung tissues for hantavirus yielded one hantavirus sequence (SEOV). In summary, these results indicate low to moderate levels of endemic hantavirus circulation, possible circulation of a flavivirus in rodent reservoirs, and the first available data on human exposures to parechoviruses in Vietnam. Although the current evidence suggests only limited exposure of humans to known rodent-borne diseases, further research is warranted to assess public health implications of the rodent trade.

  14. Developments for transactinide chemistry experiments behind the gas-filled separator TASCA

    Energy Technology Data Exchange (ETDEWEB)

    Even, Julia

    2011-12-13

    synthesised carbonyl complexes were identified by nuclear decay spectroscopy. Some complexes were studied with isothermal chromatography or thermochromatography methods. The chromatograms were compared with Monte Carlo Simulations to determine the adsorption enthalpyrnon silicon dioxide and on gold. These simulations based on existing codes, that were modified for the different geometries of the chromatography channels. All observed adsorption enthalpies (on silcon oxide as well as on gold) are typical for physisorption. Additionally, the thermalstability of some of the carbonyl complexes was studied. This showed that at temperatures above 200 C therncomplexes start to decompose. It was demonstrated that carbonyl-complex chemistry is a suitable method to study rutherfordium, dubnium, seaborgium, bohrium, hassium, and meitnerium. Until now, only very simple, thermally stable compounds have been synthesized in the gas-phase chemistry of the transactindes. With the synthesis of transactinide-carbonyl complexes a new compound class would be discovered. Transactinide chemistry would reach the border between inorganic and metallorganic chemistry. Furthermore, the in-situ synthesised carbonyl complexes would allow nuclear spectroscopy studies under low background conditions making use of chemically prepared samples. [German] Die vorliegende Arbeit befasst sich mit der Entwicklung von Experimenten hinter dem gasgefuellten Separator TASCA (TransActinide Separator and Chemistry Apparatus) zur Studie des chemischen Verhaltens der Transactinide. Zum einen wurde die Moeglichkeit der elektrochemischen Abscheidung kurzlebiger Isotope der Elemente Ruthenium und Osmium auf Goldelektroden im Hinblick auf ein Experiment mit Hassium untersucht. Aus der Literatur ist bekannt, dass bei der elektrochemischen Abscheidung einzelner Atome das Abscheidepotential signifikant vom Nernst-Potential abweicht. Die Verschiebung des Potentials haengt von der Adsorptionsenthalpie des abzuscheidenden Elements

  15. Algorithm Development and Validation of CDOM Properties for Estuarine and Continental Shelf Waters Along the Northeastern U.S. Coast

    Science.gov (United States)

    Mannino, Antonio; Novak, Michael G.; Hooker, Stanford B.; Hyde, Kimberly; Aurin, Dick

    2014-01-01

    An extensive set of field measurements have been collected throughout the continental margin of the northeastern U.S. from 2004 to 2011 to develop and validate ocean color satellite algorithms for the retrieval of the absorption coefficient of chromophoric dissolved organic matter (aCDOM) and CDOM spectral slopes for the 275:295 nm and 300:600 nm spectral range (S275:295 and S300:600). Remote sensing reflectance (Rrs) measurements computed from in-water radiometry profiles along with aCDOM() data are applied to develop several types of algorithms for the SeaWiFS and MODIS-Aqua ocean color satellite sensors, which involve least squares linear regression of aCDOM() with (1) Rrs band ratios, (2) quasi-analytical algorithm-based (QAA based) products of total absorption coefficients, (3) multiple Rrs bands within a multiple linear regression (MLR) analysis, and (4) diffuse attenuation coefficient (Kd). The relative error (mean absolute percent difference; MAPD) for the MLR retrievals of aCDOM(275), aCDOM(355), aCDOM(380), aCDOM(412) and aCDOM(443) for our study region range from 20.4-23.9 for MODIS-Aqua and 27.3-30 for SeaWiFS. Because of the narrower range of CDOM spectral slope values, the MAPD for the MLR S275:295 and QAA-based S300:600 algorithms are much lower ranging from 9.9 and 8.3 for SeaWiFS, respectively, and 8.7 and 6.3 for MODIS, respectively. Seasonal and spatial MODIS-Aqua and SeaWiFS distributions of aCDOM, S275:295 and S300:600 processed with these algorithms are consistent with field measurements and the processes that impact CDOM levels along the continental shelf of the northeastern U.S. Several satellite data processing factors correlate with higher uncertainty in satellite retrievals of aCDOM, S275:295 and S300:600 within the coastal ocean, including solar zenith angle, sensor viewing angle, and atmospheric products applied for atmospheric corrections. Algorithms that include ultraviolet Rrs bands provide a better fit to field measurements than

  16. The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear.

    Science.gov (United States)

    Chang-Chien, Ju; Yen, Yung-Chang; Chien, Kuo-Hsuan; Li, Shaun-Yow; Hsu, Tsai-Ching; Yang, Jiann-Jou

    2014-07-01

    The intercellular gap junction channels formed by connexins (CXs) are important for recycling potassium ions in the inner ear. CXs are encoded by a family of the CX gene, such as GJB2, and the mechanism leading to mutant connexin-associated diseases, including hearing loss, remains to be elucidated. In this study, using bioinformatics, we found that two zebrafish cx genes, cx27.5 and cx30.3, are likely homologous to human and mouse GJB2. During embryogenesis, zebrafish cx27.5 was rarely expressed at 1.5-3 h post-fertilization (hpf), but a relatively high level of cx27.5 expression was detected from 6 to 96 hpf. However, zebrafish cx30.3 transcripts were hardly detected until 9 hpf. The temporal experiment was conducted in whole larvae. Both cx27.5 and cx30.3 transcripts were revealed significantly in the inner ear by reverse transcription polymerase chain reaction (RT-PCR) and whole-mount in situ hybridization (WISH). In the HeLa cell model, we found that zebrafish Cx27.5 was distributed intracellularly in the cytoplasm, whereas Cx30.3 was localized in the plasma membrane of HeLa cells stably expressing Cx proteins. The expression pattern of zebrafish Cx30.3 in HeLa cells was more similar to that of cells expressing human CX26 than Cx27.5. In addition, we found that Cx30.3 was localized in the cell membrane of hair cells within the inner ear by immunohistochemistry (IHC), suggesting that zebrafish cx30.3 might play an essential role in the development of the inner ear, in the same manner as human GJB2. We then performed morpholino knockdown studies in zebrafish embryos to elucidate the physiological functions of Cx30.3. The zebrafish cx30.3 morphants exhibited wild-type-like and heart edema phenotypes with smaller inner ears at 72 hpf. Based on these results, we suggest that the zebrafish Cx30.3 and mammalian CX26 may play alike roles in the inner ear. Thus, zebrafish can potentially serve as a model for studying hearing loss disorders that result from human CX

  17. GETDB: 112122 [GETDB

    Lifescience Database Archive (English)

    Full Text Available 112122 Link to Original y[*] w[*]; P{GawB}NP0275 / TM6, P{UAS-lacZ.UW23-1}UW23-1 47A12... ; -; 47A13 Link to DGRC Genome Viewer: 112122 lola psq 275 3 FlyBase Insertion: P{GawB}NP0275 NP line. R... 662 1 Request - muscle ubiquitous sg - - - - - - - - Show 112122 DGRC Number 11212...2 Link to Original Genotype y[*] w[*]; P{GawB}NP0275 / TM6, P{UAS-lacZ.UW23-1}UW23-1 Insertion Site 47A12 ...; -; 47A13 Map Viewer Link to DGRC Genome Viewer: 112122 Related Genes lola psq Original Number 275 Chr. 3 C

  18. 乐果对金鱼的急性毒性影响%Acute Toxicity Influence on Goldfish by Dimethoate

    Institute of Scientific and Technical Information of China (English)

    谢进金; 齐兆明; 陈琳钦; 林娟娟; 冯琳; 谢进辉

    2006-01-01

    用改进的寇氏法(karber)测定了乐果对金鱼(Carassius auratus)的急性毒性.急性试验经150mg/L、188.4mg/L、234.4mg/L、291.7mg/L、360mg/L乐果暴露4d,在15℃~20℃下,24、48、72、96h的LTm值分别为297.17、289.13、259.12、238.67mg/L,其95%置信限分别为284.25~310.67、275.17~303.81、243.33~275.93、223.98~254.33mg/L.

  19. Stages in the Formation of the Romanian Mental Space

    Directory of Open Access Journals (Sweden)

    POMPEI COCEAN

    2008-01-01

    Full Text Available In the evolution of the Romanian mental space, four distinct stages can be emphasized, each of them bringing its specific contribution to its defining and structuring. These stages are the following: the forerunning, Dacian stage, the 2nd century B.C. - 106 A.D.; the incipient, Dacian-Roman stage, 105 – 275 A.D.; the structuring, proto-Romanian stage, 275 – the 6th and 7th centuries; the Romanian stage of completion and affirmation, the 8th century – nowadays. Each stage is characterized by different forms, in continuous affirmation and improvement, of interrelations between the human communities and the site, of spiritually sublimation of the physical-geographical substratum features, of the territory inhabited by them.

  20. High cycle fatigue properties of CLAM steel at 723 K and 823 K

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Yanyun; Zhai, Xiangwei; Liu, Shaojun, E-mail: shaojun.liu@fds.org.cn; Li, Chunjing; Huang, Qunying

    2015-11-15

    Highlights: • High cycle fatigue properties of CLAM steel were investigated at 723 K and 823 K. • The condition fatigue limit at N = 10{sup 7} were 275 MPa and 235 MPa at 723 K and 823 K. • Fatigue strength decreased when stress and temperature increased at 723 K and 823 K. • Dislocation density decrease and subgrain coarsening during the test process were the possible reasons for fatigue limit decrease. - Abstract: This paper highlights the results of a study on the high cycle fatigue strength and fracture mechanism of China Low Activation Martensitic (CLAM) steel. The high cycle fatigue test results showed that the fatigue strength of CLAM steel decreased with the temperature, and the condition fatigue strengths (N = 10{sup 7}) were 275 MPa and 235 MPa at 723 K and 823 K, respectively. The fractograph results indicated that the fractures were mainly initiated from the surface of the specimen.

  1. COMBUSTION CHARACTERISTICS OF TORREFIED WOOD SAMPLES OF PINUS CARREBEA AND LEUCAENA LEUCOCEPHALA GROWN IN NIGERIA

    Directory of Open Access Journals (Sweden)

    Joseph Adeola FUWAPE

    2016-12-01

    Full Text Available Torrefaction of selected wood samples of Pinus Carrebea and Leucaena Leucocephala were carried out at temperatures ranging from 200 to 300°C to improve the energy parameters of biomass and to determine the effect of torrefication temperature on the physical and combustion properties of wood selected from Pinus carrebea and Leuceanea leucocephala grown in Nigeria. In this process the biomass hemicellulose is degraded, maintaining its cellulose and lignin content. The samples were dried and heated to 225, 250, 275, and 300°C. Then the torrefied mass was subjected to basic property testing on proximate analysis and heating value was calculated in order to understand the differences between raw material and its torrefied products. Specifically, the wood blocks changed from light brown to black, stemming from the partial carbonization at the wood surface. When the temperature is 225°C, the color of the wood is between dark brown and once the torrefaction temperatures are 250 and 275°C, the colors of the wood become dark and darker respectively. The results of the proximate analysis also showed that increasing of torrefied temperature; volatile fraction was reduced while fixed carbon was increased with increase in temperature from 21.34 to 52.74 and 18.58 to 56.83 for Leucaena leucocephala and Pinus carreabeanus respectively at 225 to 300°C. The volatile content is decreased from 78.58% to 62.76% with increase in temperature. Ash content of were within 1.57-3.41% of torrefied wood. It could be observed that the High calorific value (HCV for pine ranged between 19.80 and 28.06MJ/Kg for the top, 19.93and 24.96MJ/kg for middle with 19.72and 25.96MJ/Kg for base. The values recorded for raw sample and at 275°C been the lowest and highest respectively. The High calorific value (HCV were found to be on the increase and nose dive at 300°C for the tree parts used in this research. The result revealed that for Leuceana the value increased from raw up to

  2. Two different phase-change origins with chemical- and structural-phase-changes in C doped (1.5 wt.%) In3Sb1Te2.

    Science.gov (United States)

    Lee, Y M; Lee, S Y; Sasaki, T; Kim, K; Ahn, D; Jung, M-C

    2016-12-08

    We fabricated C-doped (1.5 wt.%) In3Sb1Te2 (CIST) thin films with amorphous phase (a-CIST) using a sputter method. Two electrical-phase-changes at 250 and 275 °C were observed in the sheet resistance measurement. In order to understand the origin of these electrical-phase-changes, all samples were characterized by XRD, TEM, and HRXPS with synchrotron radiation. In a-CIST, only weak Sb-C bonding was observed. In the first electrical-phase-change at 250 °C, strong Sb-C bonding occurred without an accompanying structural/phase change (still amorphous). On the other hand, the second electrical-phase-change at 275 °C was due to the structural/phase change from amorphous to crystalline without a chemical state change.

  3. U-Pb ages of Kude and Sajia leucogranites in Sajia dome from North Himalaya and their geological implications

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hongfei; Nigel Harris; Randy Parrish; ZHANG Li; ZHAO Zidan

    2004-01-01

    U-Pb ages of zircon, monazite and xenotime from the Kude and the Sajia leucogranites in the Sajia dome of the North Himalayan tectonic unit are measured using TIMS method. The results show that the magma emplacement ages for the Kude and the Sajia leucogranite are 27.5 ±0.5 and 14.4± 0.2 Ma, respectively. Combined with published U-Pb data from the North Himalayan leucogranites, the time-span for the formation of the North Himalayan leucogranites is updated from 27.5 to 10 Ma, instead of previous 15 to 10 Ma. According to the U-Pb ages, the petrogenesis for the North Himalayan leucogranites can be constrained. It is suggested that the North Himalayan leucogranites have variety in their petrogenesis.

  4. Metalloproteins and the Pyrite-based Origin of Life: A Critical Assessment

    Science.gov (United States)

    Rivas, Mario; Becerra, Arturo; Peretó, Juli; Bada, Jeffrey L.; Lazcano, Antonio

    2011-08-01

    We critically examine the proposal by Wächtershäuser (Prokaryotes 1:275-283, 2006a, Philos Trans R Soc Lond B Biol Sci 361: 787-1808, 2006b) that putative transition metal binding sites in protein components of the translation machinery of hyperthermophiles provide evidence of a direct relationship with the FeS clusters of pyrite and thus indicate an autotrophic origin of life in volcanic environments. Analysis of completely sequenced cellular genomes of Bacteria, Archaea and Eucarya does not support the suggestion by Wächtershäuser (Prokaryotes 1:275-283, 2006a, Philos Trans R Soc Lond B Biol Sci 361: 787-1808, 2006b) that aminoacyl-tRNA synthetases and ribosomal proteins bear sequence signatures typical of strong covalent metal bonding whose absence in mesophilic species reveals a process of adaptation towards less extreme environments.

  5. Determination of Diclofenac Potassium Gel by HPLC%双氯芬酸钾凝胶含量的HPLC测定

    Institute of Scientific and Technical Information of China (English)

    周学敏; 徐群为; 张勤; 郝钦; 许荔欣

    2001-01-01

    建立了双氯芬酸钾凝胶含量的HPLC测定法。采用YWG-C18柱,以甲醇-5%醋酸水溶液为流动相,检测波长275 nm。方法平均回收率为99.55%,RSD为1.22%。%Diclofenac potassium gel was determined by HPLC, using YWG-C18 column, with methanol -5% acetic acid solution (80∶20) as the mobile phase at the detection wavelength of 275 nm. The average recovery was 99.55%, with RSD of 1.22%.

  6. Fireball ejection from a molten hot spot to air by localized microwaves.

    Science.gov (United States)

    Dikhtyar, Vladimir; Jerby, Eli

    2006-02-03

    A phenomenon of fireball ejection from hot spots in solid materials (silicon, germanium, glass, ceramics, basalt, etc.) to the atmosphere is presented. The hot spot is created in the substrate material by the microwave-drill mechanism [Jerby, Science 298, 587 (2002)10.1126/science.1077062]. The vaporized drop evolved from the hot spot is blown up, and forms a stable fireball buoyant in the air. The experimental observations of fireball ejection from silicate hot spots are referred to the Abrahamson-Dinniss theory [Nature (London) 403, 519 (2000)10.1038/35000525] suggesting a mechanism for ball-lightning initiation in nature. The fireballs observed in our experiments tend to absorb the available microwave power entirely, similarly to the plasmon resonance effect in submicron wavelengths [Nie and Emory, Science 275, 1102 (1997)10.1126/science.275.5303.1102].

  7. Life Satisfaction, Self-Esteem, and Loneliness Among LGB Adults and Heterosexual Adults in China.

    Science.gov (United States)

    Hu, Jingchu; Hu, Jize; Huang, Gang; Zheng, Xifu

    2016-01-01

    Low levels of life satisfaction have been linked to low self-esteem and loneliness, but this association has never been tested directly in LGB (lesbian/gay/bisexual) populations. We compared 275 Chinese LGB adults to 275 demographic-matched Chinese heterosexual controls on life satisfaction, self-esteem, and loneliness. LGB adults reported lower levels of self-esteem and higher levels of loneliness than heterosexuals, but similar levels of overall life satisfaction. Self-esteem partially mediated (but did not moderate) the relationship between loneliness and life satisfaction in both groups. Hierarchical regressions indicated that demographic variables, loneliness, and self-esteem can predict life satisfaction in both LGB and heterosexual adults, but explained more variance of life satisfaction in the LGB group. Thus self-esteem and loneliness play a more important role in life satisfaction for LGB rather than heterosexual Chinese adults.

  8. Thermodynamic Investigation of the Azeotropic Mixture Composed of Water and Benzene

    Institute of Scientific and Technical Information of China (English)

    NAN,Zhao-Dong(南照东); TAN,Zhi-Cheng(谭志诚)

    2004-01-01

    The molar heat capacity of the azeotropic mixture composed of water and benzene was measured by an adiabatic calorimeter in the temperature range from 80 to 320 K. The phase transitions took place in the temperature range from 265.409 to 275.165 K and 275.165 to 279.399 K. The phase transition temperatures were determined to be 272.945 and 278.339 K, which were corresponding to the solid-liquid phase transitions of water and benzene, respectively. The thermodynamic functions and the excess thermodynamic functions of the mixture relative to standard temperature 298.15 K were derived from the relationships of the thermodynamic functions and the function of the measured heat capacity with respect to temperature.

  9. Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2

    DEFF Research Database (Denmark)

    Hogan, Meghan F; Ravnskjaer, Kim; Matsumura, Shigenobu

    2015-01-01

    and dephosphorylation of the cAMP regulated CREB coactivators CRTC2 and CRTC3. In parallel, decreases in circulating insulin also increase gluconeogenic gene expression via the de-phosphorylation and activation of the forkhead transcription factor FOXO1. Hepatic gluconeogenesis is increased in insulin resistance where...... accompanying decreases in FOXO1 activity, hepatic gluconeogenic gene expression remained elevated in CRTC2S171,275A mice demonstrating that chronic increases in CRTC2 activity in the liver are indeed sufficient to promote hepatic insulin resistance and to disrupt glucose homeostasis....... increased gluconeogenic gene expression under fasting as well as feeding conditions. Circulating glucose concentrations were constitutively elevated in CRTC2S171,275A expressing mice, leading to compensatory increases in circulating insulin concentrations that enhance FOXO1 phosphorylation. Despite...

  10. Thermally Stable Siloxane Hybrid Matrix with Low Dielectric Loss for Copper-Clad Laminates for High-Frequency Applications.

    Science.gov (United States)

    Kim, Yong Ho; Lim, Young-Woo; Kim, Yun Hyeok; Bae, Byeong-Soo

    2016-04-06

    We report vinyl-phenyl siloxane hybrid material (VPH) that can be used as a matrix for copper-clad laminates (CCLs) for high-frequency applications. The CCLs, with a VPH matrix fabricated via radical polymerization of resin blend consisting of sol-gel-derived linear vinyl oligosiloxane and bulky siloxane monomer, phenyltris(trimethylsiloxy)silane, achieve low dielectric constant (Dk) and dissipation factor (Df). The CCLs with the VPH matrix exhibit excellent dielectric performance (Dk = 2.75, Df = 0.0015 at 1 GHz) with stability in wide frequency range (1 MHz to 10 GHz) and at high temperature (up to 275 °C). Also, the VPH shows good flame resistance without any additives. These results suggest the potential of the VPH for use in high-speed IC boards.

  11. 2-(Trimethylsiloxyadamantane-2-carbonitrile

    Directory of Open Access Journals (Sweden)

    Richard Betz

    2009-01-01

    Full Text Available In the crystal structure of the title compound, C14H23NOSi, cyclic dimeric units are established by two very weak hydrogen bonds of the type C—H...N with an H...N distance which is only slightly shorter than the sum of the van der Waals radii of 2.75 Å. The graph-set descriptor on the unitary level is R22(14 for the cyclic dimer.

  12. What is the Risk for Exposure to Vector-Borne Pathogens in United States National Parks?

    OpenAIRE

    Eisen, Lars; Wong, David; SHELUS, VICTORIA; Eisen, Rebecca J.

    2013-01-01

    United States national parks attract >275 million visitors annually and collectively present risk of exposure for staff and visitors to a wide range of arthropod vector species (most notably fleas, mosquitoes, and ticks) and their associated bacterial, protozoan, or viral pathogens. We assessed the current state of knowledge for risk of exposure to vector-borne pathogens in national parks through a review of relevant literature, including internal National Park Service documents and organisma...

  13. Flow of endogenous and exogenous nitrogen in different segments of the small intestine in pigs fed diets with soyabean concentrate, soyabean meal or rapeseed cake

    NARCIS (Netherlands)

    Grala, W.; Buraczewska, L.; Wasilewko, J.; Verstegen, M.W.A.; Tamminga, S.; Jansman, A.J.M.; Huisman, J.; Korczynski, W.

    1998-01-01

    Six barrows of an average initial BW 27.5±1.2 kg were used. Each pig was fitted with two cannulas in different segments of the small intestine: pig 1 in the duodenum (C1) and upper jejunum (C2), pig 2 in C2 and the lower jejunum (C3), pig 3 in C2 and C3, pig 4 in C1 and the terminal ileum (C4), pig

  14. Data mining methods for parameters forecasting of a small solar plant

    Science.gov (United States)

    Muntean, Maria; Tulbure, Adrian; Rotar, Corina

    2016-12-01

    This paper investigates the relation between the intensity of solar radiation correlated with ambient temperature and energy production, at local scale and area, using a forecasting algorithm. In the first step, using the experimental collected data, the authors have developed a suitable model to study the analyzed phenomena. The model can be applied for forecasts in the energy sector, very useful especially because UAT (territorial administrative unit) of Alba Iulia has a 275kW functional photovoltaic park.

  15. Ordered Nanopillar Structured Electrodes for Depleted Bulk Heterojunction Colloidal Quantum Dot Solar Cells

    KAUST Repository

    Kramer, Illan J.

    2012-03-30

    A bulk heterojunction of ordered titania nanopillars and PbS colloidal quantum dots is developed. By using a pre-patterned template, an ordered titania nanopillar matrix with nearest neighbours 275 nm apart and height of 300 nm is fabricated and subsequently filled in with PbS colloidal quantum dots to form an ordered depleted bulk heterojunction exhibiting power conversion efficiency of 5.6%. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Effects of temperature on gene expression in embryos of the coral Montastraea faveolata.

    KAUST Repository

    Voolstra, Christian R.

    2009-12-23

    Coral reefs are expected to be severely impacted by rising seawater temperatures associated with climate change. This study used cDNA microarrays to investigate transcriptional effects of thermal stress in embryos of the coral Montastraea faveolata. Embryos were exposed to 27.5 degrees C, 29.0 degrees C, and 31.5 degrees C directly after fertilization. Differences in gene expression were measured after 12 and 48 hours.

  17. Broadband S-band class E HPA

    NARCIS (Netherlands)

    Wanum, van M.; Dijk, van R.; Hek, de A.P.; Vliet, van F.E.

    2009-01-01

    A broadband class E High Power Amplifier (HPA) is presented. This HPA is designed to operate at S-band (2.75 to 3.75 GHz). A power added efficiency of 50% is obtained for the two stage amplifier with an output power of 35.5 dBm on a chip area of 5.25 times 2.8 mm2.

  18. Broadband S-band Class E HPA

    NARCIS (Netherlands)

    Wanum, M. van; Dijk, R. van; Hek, A.P. de; Vliet, F.E. van

    2009-01-01

    A broadband class E High Power Amplifier (HPA) is presented. This HPA is designed to operate at S-band (2.75 to 3.75 GHz). A power added efficiency of 50% is obtained for the two stage amplifier with an output power of 35.5 dBm on a chip area of 5.25 × 2.8 mm2.

  19. Prevalence of stress in Casablanca medical students: a cross-sectional study

    OpenAIRE

    Ben Loubir, Dalal; Serhier, Zeineb; Diouny, Samir; Battas, Omar; Agoub, Mohamed; Othmani, Mohammed Bennani

    2014-01-01

    Introduction Recently, an important literature data has reported that medical students experience stress more than students in other disciplines. In contrast, there is a significant shortage of the stress impact on the academic performance. The primary purpose of our study was to determine the prevalence of stress among Casablanca Medical students and to investigate if there is an association between stress and academic skills. Methods A total of 275 participants studying at Casablanca Medica...

  20. Synthesis, spectroscopy, and electrochemistry of ionic hosts for organic electronics

    Science.gov (United States)

    Shavaleev, Nail M.; Nazeeruddin, Mohammad K.

    2015-02-01

    We report on charge- and ion-transport ionic hosts made from an imidazolium-cation-modified aryl-1,2,4-triazole, phosphineoxide-carbazole, and phosphineoxide. The hosts are white solids that have short-wavelength absorption cut-off at 28,200 cm-1) and that exhibit oxidation at (-2.75) V against ferrocene with a wide redox gap of >3.9 V.

  1. Polarized Light Experiment, Presa Don Martin, Mexico

    Science.gov (United States)

    1989-01-01

    This is a single scene from a pair (frames 021 and 024) to study the effects of polarized light in Earth Observations. One scene was exposed with vertically polarized light, the other, horizontally. The subject in this study, is a lake behind Presa (dam) Don Martin (27.5N, 100.5W) on thge edge of the Rio Grande Plain near it's boundry with the Sierra Madre Oriental in Coahuila, Mexico.

  2. Polarized Light Experiment, Presa Don Martin, Coahuila, Mexico

    Science.gov (United States)

    1989-01-01

    This is a single scene from a pair (frames 021 and 024) to study the effects of polarized light in Earth Observations. One scene was exposed with vertically polarized light, the other, horizontally. The subject in this study, is a lake behind Presa (dam) Don Martin (27.5N, 100.5W) on the edge of the Rio Grande Plain near it's boundry with the Sierra Madre Orientral in Coahuila, Mexico.

  3. Carbon Nanotube Synthesis an Detection: Limiting the Environmental Impact of Novel Technologies

    Science.gov (United States)

    2009-06-01

    recognized as contributors to smog and lower atmosphere ozone formation, thereby exacerbating respiratory diseases (e.g., 1976 report from the...nanotube integration. Nanotechnology 2007, 18, 075603. [40] Stein, S.E.; Fahr , A. High-temperature stabilities of hydrocarbons. J. Phys. Chem, 1985...Centers for Disease Control and Prevention. [42] Dean, K.A. A new era: Nanotube displays. Nature Photonics 2007, 1 (5), 273- 275. [43

  4. Advertising Bans and the Substitutability of Online and Offline Advertising

    OpenAIRE

    Goldfarb, Avi; Tucker, Catherine Elizabeth

    2010-01-01

    The authors examine whether the growth of the Internet has reduced the effectiveness of government regulation of advertising. They combine nonexperimental variation in local regulation of offline alcohol advertising with data from field tests that randomized exposure to online advertising for 275 different online advertising campaigns to 61,580 people. The results show that people are 8% less likely to say that they will purchase an alcoholic beverage in states that have alcohol advertising b...

  5. 大青叶蝉寄主植物名录%Catalogue of Host Plants of Cicadella viridi L.(Hemiptera: Cicadellidae)

    Institute of Scientific and Technical Information of China (English)

    高宇; 韩琪; 徐博

    2015-01-01

    在田间调查和查阅国内外文献的基础上,整理出大青叶蝉(Cicadella viridis L.)寄主植物名录,主要涉及裸子植物、双子叶植物和单子叶植物,共计3纲65科275种(含变型、亚种和变种).

  6. Codon Constraints on Closed 2D Shapes,

    Science.gov (United States)

    2014-09-26

    yields the "vase" of Rubin’s famous figure-ground illusion observed as erly as 1819 by Turton .] Thus, knowing which side is figure determines the...inflections), then the segment is designated as a type 0 codon (see Fig. 4). Those with two zeroes are called type 2 codons. If a segment has exactly one...34: Marr, D. (1976) Early processing of visual information. Phil. Trans. Roy. Soc. Lond., 275:483-524. Marr, D. (1982) Vision: A Computational

  7. Tallinna Moefestival 88

    Index Scriptorium Estoniae

    1989-01-01

    1988. a. 28. nov.-5. dets. toimunud Tallinna Moefestivalist, kus üleliidulisel autorikonkursil osales 195 kunstnikku 275 kollektsiooniga; 10 võrdset preemiat said: Ugis Jankavs, Natalja Tjutjunova-Orskaja, Ivo Nikkolo, Olga Lipatova, Larissa Tkatshenko, Anzhelina Zahharova, Vladimir Bulgakov, Anu Hint, Zanete Meldere, Nadezhda Prishep; eripreemiad said: Ljudmila Aristova (rahvuslikel ainetel loodud kollektsioon), Nonna Melikova ja Svetlana Talõsheva (fantaasia), Andra Treibana (avangard)

  8. Domain Modeling: NP_060012.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_060012.3 chr1 ADR1 DNA-BINDING DOMAIN FROM SACCHAROMYCES CEREVISIAE, NMR, 25 STR...UCTURES c2adra_ chr1/NP_060012.3/NP_060012.3_holo_242-299.pdb psi-blast 244A,246A,247M,249R,263D,275A,277G,278D,280I,296M,297N _ZN 0 ...

  9. Individual Differences and Short-Term Military Factors Associated With Unhealthy Weight Control Behaviors Among Active Duty and Reserve Army Soldiers

    Science.gov (United States)

    2009-03-01

    dieting in binge eating disorder: Etiology and treatment implications. Clinical Psychology Review , 19(1), 25-44. Hudson, J. I., Hiripi, E., Pope, H...eating among males. Clinical Psychology Review , 27(5), 582-606. 123 Rodin, J., Silberstein, L., & Striegel-Moore, R. (1984). Women and weight...dissatisfaction: A meta-analytic review. Clinical Psychology Review , 21(4), 521-551. Wynd, C. A., & Ryan-Wenger, N. A. (2004). Factors predicting health

  10. Clivagens, conjuntura económica e comportamento eleitoral em Portugal: uma análise das legislativas de 1995 com dados agregados

    Directory of Open Access Journals (Sweden)

    André Freire

    2000-04-01

    Full Text Available Este artigo analisa o impacte das estruturas de clivagem (centro-periferia; religiosidade-secularização; urbano-rural; capital-trabalho e da conjuntura económica sobre os alinhamentos dos eleitores, nas eleições legislativas portuguesas de 1995. Em termos metodológicos, utilizou-se a análise de dados agregados, tomando como unidades de análise os 275 concelhos do Continente.

  11. Semiannual Technical Summary, 1 April-30 September 1993

    Science.gov (United States)

    1993-12-01

    aftershock sequence occurred in the Southern Sinkiang province only three days before the explosion, and this gave an opportunity to make some interesting...expected uncertainty for all arrays. It is also noted that a large earthquake and aftershock sequence occurred in the Southern Sinkiang province only three...we will just note that on 2 October (day 275) an aftershock sequence occurred in the S. Sinkiang prov- ince. Furthermore, the last day, 5 October 1993

  12. Risk Factors Influencing Conception Rate in Holstein Heifers before Artificial Insemination or Embryo Transfer

    OpenAIRE

    2016-01-01

    The objective of this study was to show the risk factors affecting the conception rate in Holstein heifers after synchronization of estrus. A total of 275 Holstein heifers housed in a free barn were used for the experiment. The herd was visited regularly at four week intervals for synchronization of estrus using Heatsynch and CIDR-Heatsynch protocols. A group of four to 14 animals, depending on the availability, were referred to the experiment at each visit. Estrus induction rates in the two ...

  13. Combined Hydrophobic/Oleophobic Membrane Separation and Extraction for Fuel Treatment (Briefing Charts)

    Science.gov (United States)

    2015-03-24

    Extraction for Fuel Treatment 5a. CONTRACT NUMBER In-House 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Guenthner, Andrew; Reams, Josiah...SEPARATION AND EXTRACTION FOR FUEL TREATMENT 24 March 2015 Presenter: Dr. Andrew Guenthner Air Force Research Laboratory, AFRL/RQRP Ph: 661-275... extraction fluids. The attainable partition coefficients for typical sulfur contaminants are marginal for operation of a portable fuel treatment

  14. Abacus of Frozen Conflicts

    Science.gov (United States)

    2010-06-01

    Italy in 275 BC, the Gallic, Gothic , and Heruli invasions of the Roman Empire in the third century AD, and the Muslim conquest of Persia in 636 AD.4...war. A. THE SPIRAL MODEL The theoretical literature of interstate conflict is dominated by two conceptual models, classical Deterrence Theory...large body of literature on the causes of war, there is a stark contrast in the ways in which political scientists and historians view the concept

  15. Defining the erythrocyte binding domains of Plasmodium vivax tryptophan rich antigen 33.5.

    Directory of Open Access Journals (Sweden)

    Hema Bora

    Full Text Available Tryptophan-rich antigens play important role in host-parasite interaction. One of the Plasmodium vivax tryptophan-rich antigens called PvTRAg33.5 had earlier been shown to be predominantly of alpha helical in nature with multidomain structure, induced immune responses in humans, binds to host erythrocytes, and its sequence is highly conserved in the parasite population. In the present study, we divided this protein into three different parts i.e. N-terminal (amino acid position 24-106, middle (amino acid position 107-192, and C-terminal region (amino acid position 185-275 and determined the erythrocyte binding activity of these fragments. This binding activity was retained by the middle and C-terminal fragments covering 107 to 275 amino acid region of the PvTRAg33.5 protein. Eight non-overlapping peptides covering this 107 to 275 amino acid region were then synthesized and tested for their erythrocyte binding activity to further define the binding domains. Only two peptides, peptide P4 (at 171-191 amino acid position and peptide P8 (at 255-275 amino acid position, were found to contain the erythrocyte binding activity. Competition assay revealed that each peptide recognizes its own erythrocyte receptor. These two peptides were found to be located on two parallel helices at one end of the protein in the modelled structure and could be exposed on its surface to form a suitable site for protein-protein interaction. Natural antibodies present in the sera of the P. vivax exposed individuals or the polyclonal rabbit antibodies against this protein were able to inhibit the erythrocyte binding activity of PvTRAg33.5, its fragments, and these two synthetic peptides P4 and P8. Further studies on receptor-ligand interaction might lead to the development of the therapeutic reagent.

  16. Content Analysis of Reporting Templates and Free-Text Radiology Reports

    OpenAIRE

    Hong, Yi; Kahn, Charles E.

    2013-01-01

    The Radiological Society of North America (RSNA) has developed a set of templates for structured reporting of radiology results. To measure how much of the content of conventional narrative (“free-text”) reports is covered by the concepts included in the RSNA reporting templates, we selected five reporting templates that represented a variety of imaging modalities and organ systems. From a sample of 8,275 consecutive, de-identified radiology reports from an academic medical center, we identif...

  17. CTC Sentinel. Volume 7, Issue 4, January 2014

    Science.gov (United States)

    2014-01-01

    Symptoms,” Science Translational Medicine 5:207 (2013): pp. 143-153, for a recent report on blocking Ebola in non- human primates by using a...to new discoveries in terms of medicine , but also provide information that enables the biohacker. In a world accustomed to well-defined toxin...pp. 244, 267, 275; Lorenzo Vidino, Al Qaeda in Europe. The New Battleground of Inter- national Jihad (New York: Prometheus Books, 2006), pp. 322

  18. Effects of G-Induced Stress on Pulmonary Circulation.

    Science.gov (United States)

    1976-12-01

    INTRODUCTION Previous studies have demonstrated that, in subjects, NI results in a significant and reproducible natriuresis and diuresis , and a...a natriuresis similar to that of water immersion (33). The noticeable differences between the two con- ditions are: the higher airway resistance...D. C. Duncan, and L. M. Fishman. Characterization of the natriuresis caused in normal man by immersion in water. Clin Sci 43:275-287 (1972). 14

  19. Upper extremity injury management by non-physician emergency practitioners in rural Uganda: A pilot study

    Directory of Open Access Journals (Sweden)

    Daniel S. Frank

    2014-03-01

    Conclusions: When compared to the standardised Quick DASH outcomes (no work limitation at 27.5 vs. work limited by injury at 52.6 the non-physician clinicians appear to be performing upper extremity repairs with good outcomes. The key variable to successful repair was the initial injury type. Although accommodations needed to be made to the standard Quick DASH protocol, the tool appears to be usable in non-traditional settings.

  20. Synthesis and Structural Characterization of New High-Valent Inorganic Fluorine Compounds and their Oxidizing Properties. Volume 2

    Science.gov (United States)

    1992-02-01

    Franklin, J.L., J. Am. Chem. Soc., 1961, 83, 1813. " Rosums, P., Stafast, H. and Bock, H., Chem. Plys. Lett., 1975, JA, 275. ° Prasad, S.R. and Singh , A.N...191; NMR spectrum, but no r~sonance attributable to Tej -’ 2 - closely celated anioni are under-way both in our laboratories could tie observed. T’he N

  1. Clinical Investigation Program: Annual Progress Report

    Science.gov (United States)

    1992-09-30

    Failure ....... 82 90/124 C The Effectiveness of Octreotide (Sandostatin*) to Prevent Pancreatitis Caused by Endoscopic Pancreacto- Biliary Procedures: A...203 T Cryoprecipitate in the Treatment of Seroma . 275 92/204 0 Effect of Intravenous Erythromycin on Post- Operative Ileus ...JE: Cutaneous sarcoidal granulo- mas in a patient with primary biliary cirrhosis. Cutis 49:271- 274, 1992. Homas PB, David-Bajar KM, Fitzpatrick JE

  2. Effect of Structure on the Initiation and Ignition Chemistry of Energetic Ionic Liquids

    Science.gov (United States)

    2010-06-30

    products were sampled using a quartz microprobe and the products were analyzed using a triple quadrupole mass spectrometer. When possible, the...has a height of 27.5 cm and an inner diameter of 5 cm approximately. The CRT/FTIR technique has been described in detail in a previous work.1 The...1,2,4-triazolium nitrate (4ATN) were determined by numerical techniques . The supplementary compounds studied for comparison were 4-amino-1,2,4

  3. Species-richness of the Anopheles annulipes Complex (Diptera: Culicidae) Revealed by Tree and Model-Based Allozyme Clustering Analyses

    Science.gov (United States)

    2007-01-01

    and systematics ofAnopheles: insights from a molecular phy· logeny of Australasian mosquitoes. Molecular Phylogenetics and Evolution 9: 262-275. Foley... systematics and pop- ulation studies. Sydney: Academic Press. Roscnberg NA, Burke T, Elo K, Feldman MW, Freidlin PJ, Groenen MAM, Hillel J, Maki·Taniia...of molecular-functional variation patterns among butterfly species complexes IColias: Lepidoptera , Pieridae). Molecular Ecology 12: 1265-1275. © 2007

  4. Efficient optical trapping and visualization of silver nanoparticles

    DEFF Research Database (Denmark)

    Bosanac, Lana; Aabo, Thomas; Bendix, Pól Martin

    2008-01-01

    We performed efficient optical trapping combined with sensitive optical detection of individual silver nanoparticles. The particles ranging in size from 20 to 275 nm in diameter were trapped in three dimensions using low laser power by minimizing spherical aberrations at the focus. The optical...... forces were quantified, and we found that the larger the particle, the stronger the optical force. The particles were imaged by an additional strongly scattered laser....

  5. A Comparison of Proximal Tibia and Proximal Humerus Infusion Rates of Plasma Under High Pressure Using the EZ IO Intraosseous Device in the Adult Swine (Sus scrofa) Hypovolemic Model

    Science.gov (United States)

    2013-01-10

    plasma under high pressure using the EZ IO intraosseous device in the adult swine (Sus scrofa ) hypovolemic model. FWH20100171A FWH20100171ALairet...resuscitation, swine, sus scrofa U U U SAR Vikhyat Bebarta, MD 210-275-3794 WHASC- Animal Final Report 170ct2012 1. Protocol Number: FWH20100171A 2...the EZ 10 intraosseous device in the adult swine (Sus scrofa ) hypovolemic model. 4. Principal Investigator PI): Name Rank Date of Branch Staff

  6. The life and health challenges of young Malaysian couples: results from a stakeholder consensus and engagement study to support non-communicable disease prevention

    OpenAIRE

    S. Norris; Anuar, H; Matzen, P; Cheah, J.; Jensen, B.; Hanson, Mark A.

    2014-01-01

    BACKGROUND: Malaysia faces burgeoning obesity and diabetes epidemics with a 250% and 88% increase respectively between 1996 and 2006. Identifying the health challenges of young adults in Malaysia, who constitute 27.5 % of the population, is critical for NCD prevention. The aim of the study was two-fold: (1) to achieve consensus amongst stakeholders on the most important challenge impacting the health of young adults, and (2) to engage with stakeholders to formulate a NCD prevention framework....

  7. Three National Standardization Technical Committees Authorized By SAC

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ In December, 2004, the Standardization Administration of China (SAC) has approved the establishments of three National Standardization Technical Committees. They are the National Standardization Technical Committees for Environmental Protection Products (SAC/TC275), for Safety Management of Agricultural Transgenic Biology (SAC/TC276) and for Testing of New Varieties of Plant (SAC/TC277).The National Standardization Technical Committee for Environmental Protection Products is responsible for the development and revision of national standards in the following fields:

  8. Food source and residual efficacy of chlorfenapyr on sealed and unsealed concrete

    Science.gov (United States)

    Adult Tribolium castaneum (Herbst), the red flour beetle, were exposed at 1 day, and 2, 4, and 6 weeks post-treatment on sealed and unsealed concrete arenas treated with chlorfenapyr at rates of 2.8, 6.9, 13.5, 20.6, 27.5 mg active ingredient/m2. Beetles were held either with or without flour, and a...

  9. Water vapor pressure over molten KH2PO4 and demonstration of water electrolysis at ∼300ºC

    DEFF Research Database (Denmark)

    Berg, Rolf W.; Nikiforov, Aleksey Valerievich; Petrushina, Irina

    2016-01-01

    A new potentially high-efficiency electrolyte for water electrolysis: molten monobasic potassium phosphate, KH2PO4 or KDP has been investigated at temperatures ∼275–325 °C. At these temperatures, KH2PO4 was found to dissociate into H2O gas in equilibrium with a melt mixture of KH2PO4—K2H2P2O7—KPO3...

  10. Policonsumo simultâneo de drogas entre estudantes de graduação da área de ciências da saúde de uma universidade: implicações de gênero, sociais e legais, Santo André - Brasil

    OpenAIRE

    Maria do Perpétuo Socorro de Sousa Nóbrega; Laura Simich; Carol Strike; Bruna Brands; Norman Giesbrecht; Akwatu Khenti

    2012-01-01

    Estudio transversal que busca comprender los patrones de poli-consumo simultáneo de drogas y sus consecuencias de genero, sociales y legales entre estudiantes universitarios. 275 estudiantes de las ciencias de la salud de pregrado de una universidad en Santo André, Brasil participaran en el estudio. El policonsumo simultáneo estuvo presente en 27,9% de los estudiantes de la muestra. Combinaciones: alcohol + marihuana; alcohol + medicamentos de prescripción; alcohol + tabaco + cannabis; tabaco...

  11. Experiment list: SRX559607 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =asynchronous cells || experiment_batch_number=Batch 1 || strain=YAEH275= BY4741 but PGAL1-3HA-TOP1 (KanMx6)...SRX559607 sacCer3 TFs and others DNA-RNA hybrids Yeast strain BY4741 NA 20623754,93.8,60.2,0 GSM1402302: Bat...ch1 ChIP-seq PGAL::TOP1rnh1drnh201d; Saccharomyces cerevisiae; ChIP-Seq source_name

  12. A Review of Optically Controlled Microwave Devices and Circuits

    Science.gov (United States)

    1992-09-01

    Japanese Journal of Applied Physics , Vol. 19, No. 1, pp. L27-29, January 1980. 26. Gammel, J. C., Ballantyne, J. M...34Comments on ’High Speed Photoresponse Mechanism of a GaAs MESFET’," Japanese Journal of Applied Physics , Vol. 19, No. 5, pp. L273-275, May 1980. 27...818, June 1987, Las Vegas, Nv. 55. Umeda, T., Cho, Y., Shibatomi, A., "Picosecond HEMT Photodetector," Japanese Journal of Applied Physics

  13. Detection of the excited carbon lines at decameter waves in some galactic objects

    Energy Technology Data Exchange (ETDEWEB)

    Konovalenko, A.A.

    1984-12-01

    The absorption lines C638..cap alpha..-C641..cap alpha.. are detected at 25 MHz in the region with galactic coordinates l/sub 2/=75 deg; b/sub 2/=0 deg and near the NGC 2024 nebulae. The observed parameters of lines can be only explained in the frame of the low-temperature dielectronic recombination mechanism. The advantages of decametric observations of carbon recombination lines in the various components of the interstellar medium are pointed out.

  14. Trace metal levels in nearshore sediments close to industrial discharges off Cuddalore (Bay of Bengal)

    Digital Repository Service at National Institute of Oceanography (India)

    Joseph, T.; Balachandran, K.K.; Nair, M.; Das, V.K.; Nair, K.K.C.; Paimpillii, J.S.

    97.23 2.75 0.02 °e Table 2 - Sediment Characteristics alon/? different transects(Ran/?es!~ndA vera/?esj ! Transect Sand % Clay % Silt % Organic carbon (mg/g) ! Tl 54.32-98.73 0.30- 8.00 0.02-37.68 2.58.14.21 (89.24) (3.85) (6.90) (5.44) T2 16...

  15. Observation of Coulomb effects in production of. pi. sup +. pi. sup minus , p. pi. sup minus , and K sup + K minus pairs in pp collisions at 27. 5 GeV/ c

    Energy Technology Data Exchange (ETDEWEB)

    Wiencke, L.R.; Church, M.D.; Gottschalk, E.E.; Hylton, R.A.; Knapp, B.C.; Sippach, W.; Stern, B.J. (Columbia University, Nevis Laboratories, Irvington, New York 10533 (United States)); Hartouni, E.P.; Jensen, D.A.; Klima, B.; Kreisler, M.N.; Rabin, M.S.Z.; Strait, J.B.; Uribe, J. (Department of Physics and Astronomy, University of Massachusetts, Amherst, Massachusetts 01003 (United States)); Christian, D.C.; Gutierrez, G.; Holmes, S.D.; Wehmann, A. (Fermilab, Batavia, Illinois 60510 (United States)); Avilez, C. (Instituto de Fisica, Universidad de Guanajuato, Leon, Guanajato (Mexico)); Forbush, M.; Huson, F.R.; White, J.T. (Department of Physics, Texas A M University, College Station, Texas 77843 (United States))

    1992-11-01

    In a study of collisions of 27.5 GeV/{ital c} protons in liquid hydrogen we have observed enhanced production of oppositely charged hadron pairs when the relative velocity of the two hadrons in the pair rest frame approaches {alpha}{ital c}. The scale and velocity dependence of the enhancement agree well with the effect of the attractive Coulomb interaction as described by the Gamow factor.

  16. Manpower Management (Officer and Enlisted) AFSC 74XX/733XX

    Science.gov (United States)

    1989-03-01

    SIGNIFICANTLY CHANGED 94 E340 REVIEW MISSION STATEMENTS 94 E310 IDENTIFY ASSUMED OR INFERRED WORK 94 E331 RESEARCH HISTORY OF MANPOWER ACTIONS 90 E349... E331 RESEARCH HISTORY OF MANPOWER ACTIONS 100 N906 EVALUATE ORGANIZATIONAL STRUCTURES 100 E275 COLLECT WORKLOAD DATA 100 E274 COLLECT MAN-HOUR DATA...INFERRED WORK 89 E273 COLLECT FAMILIARIZATION INFORMATION 78 E331 RESEARCH HISTORY OF MANPOWER ACTIONS 78 E315 INTERVIEW WORK CENTER PERSONNEL 78

  17. Catastrophising, pain, and disability in patients with nonspecific low back pain

    OpenAIRE

    2015-01-01

    Background: Attention has been drawn to examining the contributions of “catastrophising” to the prediction of pain and disability in individuals with low back pain (LBP). Objectives: This study investigated the proportion of patients with LBP who engaged in catastrophic thinking about pain and its association with pain intensity and disability. We also investigated the components of pain catastrophising that is predictive of disability. Methods: A total of 275 participants with nonspeci...

  18. Wage-Tenure Profiles in Contractual Labor Markets,

    Science.gov (United States)

    1981-11-01

    Luis and Andrew Weiss, "Self-Selection in the Labor Market," American Economic Review 71, June 1981, 275-84. Hall, Robert, "The Importance of Lifetime...Efficiency, Boston, M.I.T. University Press, 1965. Johnson, George E., "Economic Analysis of Trade Unionism," American Economic Review 65, May 1975, 23-8...Profiles, Productivity and Hours Restrictions," American Economic Review 71, September 1981, 606-20. Mincer, Jacob, and Boyan Jovanovich, "Labor

  19. Turbine Engine Control Synthesis. Volume 1. Optimal Controller Synthesis and Demonstration

    Science.gov (United States)

    1975-03-01

    stability. rolume 11 contains three Appendices. Appendix A contains the details of engine math models. The software for the wind tu reel -ontroller is...aspects of optimal control. Volume II contains primarily data concerning the NASA component engine model and software for the wind tunnel test con...PTPB.NRTTB,6) Turbine FN 275 WT WTTNPB N * PB/TB 276 PBDLTB = PB (TB - TCD) 277 ETAB - FUNI(19, PBDLTB, 35) Combustion efficiency 278 CALL PROCOM (0

  20. Cerebral control and survival after stereotactic radiotherapy of brain metastases; Zerebrale Kontrolle und Ueberleben nach stereotaktischer Strahlentherapie von Hirnmetastasen

    Energy Technology Data Exchange (ETDEWEB)

    Arnold, Elmar Till

    2014-06-04

    This retrospective study, including 275 patients who underwent stereotactic radiotherapy due to brain metastases between 2003 and 2008, investigates influencing factors regarding cerebral control and survival, symptomatic effects and a potential benefit for patients older than 70 years. We were able to identify risk factors for remote brain failure which leads to a therapeutic recommendation. Furthermore we confirm a positive symptomatic effect and a benefit of stereotactic readiotherapy for patients over 70 years.