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Sample records for bohrium 266

  1. 32 CFR 266.5 - Responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 266.5 Section 266.5 National... § 266.5 Responsibilities. (a) The Inspector General of the Department of Defense shall: (1) Serve as the... other nonprofit institutions for which the Department of Defense has assumed oversight...

  2. 32 CFR 266.3 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Definitions. 266.3 Section 266.3 National... AUDITS OF STATE AND LOCAL GOVERNMENTS, INSTITUTIONS OF HIGHER EDUCATION, AND OTHER NONPROFIT INSTITUTIONS § 266.3 Definitions. Terms used in this part are defined in OMB Circulars A-128 and A-133 with...

  3. Dicty_cDB: SLA266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLA266 (Link to dictyBase) - - - Contig-U16382-1 SLA266Z (Link... to Original site) - - SLA266Z 742 - - - - Show SLA266 Library SL (Link to library) Clone ID SLA266 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLA2-C/SLA266Q.Seq.d/ Representative seq. ID SLA26...6Z (Link to Original site) Representative DNA sequence >SLA266 (SLA266Q) /CSM/SL/SLA2-C/SLA266Q.Seq.d/ XXXXX...TGTCCACAGAAAATGTTTCTAAAC AATTAATAAATATGTTGTATTTTATTTAAAAA sequence update 1997. 6. 5 Translated Amino Acid s

  4. 21 CFR 26.6 - Equivalence assessment.

    Science.gov (United States)

    2010-04-01

    ... OF PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS... Specific Sector Provisions for Pharmaceutical Good Manufacturing Practices § 26.6 Equivalence...

  5. 24 CFR 266.110 - Reserve requirements.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Reserve requirements. 266.110... Finance Agency Requirements § 266.110 Reserve requirements. (a) HFAs with top-tier designation or overall... establish a reserve account funded in accordance with the requirements set forth in paragraph (b) of...

  6. 39 CFR 266.10 - Computer matching.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Computer matching. 266.10 Section 266.10 Postal... Computer matching. (a) General. Any agency or Postal Service component that wishes to use records from a... records must submit its proposal to the Postal Service Manager Records Office. Computer matching...

  7. Hypersensitisation using 266nm Laser Light

    DEFF Research Database (Denmark)

    Sørensen, Henrik Rokkjær; Canning, John; Kristensen, Martin

    UV-hypersensitisation using 266nm VW-light on hydrogenated Ge-doped fibre is reported. The optimum fluence to be between 5 to 10 kJ/cm2, coinciding with results obtained using 355nm light, indicating same end-process in both reactions.......UV-hypersensitisation using 266nm VW-light on hydrogenated Ge-doped fibre is reported. The optimum fluence to be between 5 to 10 kJ/cm2, coinciding with results obtained using 355nm light, indicating same end-process in both reactions....

  8. Properties of an $\\alpha$ particle in a Bohrium $270$ Nucleus under the Generalized Symmetric Woods-Saxon Potential

    CERN Document Server

    Lütfüoğlu, B C

    2016-01-01

    The energy eigenvalues and the wave functions of an $\\alpha$ particle in a Bohrium $270$ nucleus were calculated by solving Schr\\"odinger equation for Generalized Symmetric Woods-Saxon potential. Using the energy spectrum by excluding and including the quasi-bound eigenvalues, entropy, internal energy, Helmholtz energy, and specific heat, as functions of reduced temperature were calculated. Stability and emission characteristics are interpreted in terms of the wave and thermodynamic functions. The kinetic energy of a decayed $\\alpha$ particle was calculated using the quasi-bound states, which is found close to the experimental value.

  9. Laser hypersensitisation using 266nm light

    DEFF Research Database (Denmark)

    Sørensen, Henrik Rokkjær; Canning, J.; Kristensen, Martin

    2005-01-01

    UV hypersensitisation using CW 266 nm light on hydrogenated Ge-doped fibre is reported. The optimum sensitisation fluence is found to be in the range of 5 to 10 kJ/cm2, coinciding with previous results obtained using 355 nm light, indicating the same end-process used in the photochemical reaction...

  10. 20 CFR 266.7 - Accountability of a representative payee.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Accountability of a representative payee. 266.7 Section 266.7 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT REPRESENTATIVE PAYMENT § 266.7 Accountability of a representative payee. (a) A...

  11. 40 CFR 266.111 - Standards for direct transfer.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.111 Standards for... boilers and industrial furnaces subject to §§ 266.102 or 266.103 if hazardous waste is directly transferred from a transport vehicle to a boiler or industrial furnace without the use of a storage unit....

  12. 38 CFR 17.266 - Copyrights and patents.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Copyrights and patents. 17.266 Section 17.266 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Grants for Exchange of Information § 17.266 Copyrights and patents. If a grant-supported program...

  13. 24 CFR 266.210 - HUD-retained review functions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false HUD-retained review functions. 266.210 Section 266.210 Housing and Urban Development Regulations Relating to Housing and Urban... Program Requirements § 266.210 HUD-retained review functions. Certain functions are retained by...

  14. 49 CFR 266.13 - Distribution of funds.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Distribution of funds. 266.13 Section 266.13 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... TRANSPORTATION ACT § 266.13 Distribution of funds. (a) Formula. Funds appropriated for or reallocated in...

  15. 266Bh的α衰变性质研究%Alpha-decay Properties of 266Bh

    Institute of Scientific and Technical Information of China (English)

    秦芝; 杨维凡; 甘再国; 范红梅; 郭俊盛; 徐瑚珊; 肖国青; 吴晓蕾; 丁华杰; 吴王锁; 黄文学; 雷祥国; 徐岩冰; 袁晓华; 郭斌

    2006-01-01

    报道了利用兰州重离子研究装置提供的26Mg重离子束流轰击243Am靶产生和鉴别已知超重核素266Bh的实验结果.利用转轮收集探测装置依靠母子核遗传关系通过观测Bh同位素与其子核Db和Lr之间的α-α关联事件来鉴别266Bh. 实验中观测到266Bh的α能量为(9.03 ± 0.08) MeV, 与日本理化学研究所在合成113号元素中第一个衰变链中观测到266Bh的α能量为9.07 MeV相近. 266Bh的半衰期为0.66+0.59-0.26 s, 从实验得到的Qα也符合Z=107的Qα随中子数变化的系统性.%The isotope of 266Bh was produced and identified definitely in bombardments of 243Am target with 162 MeV 26Mg ions at HIRFL. Identification was made by observation of correlated α-particle decays between the Bh isotopes and their Db and Lr daughters using a rotating wheel system. The measured α energy for 266Bh is (9.03±0.08) MeV, and this value close to the 9.07 MeV for 266Bh observed in the first chain of element 113 at RIKEN. The half-life of 266Bh is 0.66+0.59 -0.26 s. The Qα value derived from this experiment fits well into the general trend in a "Qα-N systematics" for the isotopes with Z = 107.

  16. 40 CFR 266.202 - Definition of solid waste.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Definition of solid waste. 266.202 Section 266.202 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... inactive ranges. However, “use for intended purpose” does not include the on-range disposal or burial...

  17. 16 CFR 1500.266 - Notice of sampling.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Notice of sampling. 1500.266 Section 1500.266 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT... Notice of sampling. When a sample of a hazardous substance offered for import has been requested by...

  18. Dicty_cDB: SFC266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ore E Sequences producing significant alignments: (bits) Value SFC266 (SFC266Q) /...nificant alignments: (bits) Value N AC115592 |AC115592.2 Dictyostelium discoideum...uences producing significant alignments: (bits) Value A23559( A23559 )dihydroorot

  19. 40 CFR 266.109 - Low risk waste exemption.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.109 Low risk waste exemption. (a) Waiver of DRE standard. The DRE standard of § 266.104(a) does not apply if the boiler or... boiler or industrial furnace that is exempt under this section must conduct dispersion modeling...

  20. 40 CFR 421.266 - Pretreatment standards for new sources.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 28 2010-07-01 2010-07-01 true Pretreatment standards for new sources. 421.266 Section 421.266 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Secondary Precious...

  1. 40 CFR 266.105 - Standards to control particulate matter.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.105 Standards to control particulate matter. (a) A boiler or industrial furnace burning hazardous waste may...

  2. 40 CFR 266.102 - Permit standards for burners.

    Science.gov (United States)

    2010-07-01

    ... exempt from the particulate matter standard under § 266.105(b); (iii) For cement kilns and light-weight... that the hazardous waste, other fuels, and industrial furnace feedstocks fired into the boiler or... based on either trial burn results or alternative data included with part B of a permit...

  3. 40 CFR 266.106 - Standards to control metals emissions.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.106... operators of facilities with more than one on-site stack from a boiler, industrial furnace, incinerator, or...) Owners and operators of facilities with more than one onsite stack from a boiler, industrial...

  4. 40 CFR 266.112 - Regulation of residues.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.112 Regulation of residues. A residue derived from the burning or processing of hazardous waste in a boiler or industrial... boiler or industrial furnace unit. At a minimum, the following shall be recorded. (1) Levels...

  5. 40 CFR 266.103 - Interim status standards for burners.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.103... boiler or industrial furnace that on or before August 21, 1991 is either in operation burning or... a boiler or industrial furnace is located at a facility that already has a permit or interim...

  6. 40 CFR 266.104 - Standards to control organic emissions.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.104...) of this section, a boiler or industrial furnace burning hazardous waste must achieve a destruction... fired to the boiler or industrial furnace; and Wout= Mass emission rate of the same POHC present...

  7. 40 CFR 266.101 - Management prior to burning.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.101 Management prior to burning. (a) Generators. Generators of hazardous waste that is burned in a boiler or industrial furnace... burned in a boiler or industrial furnace are subject to part 263 of this chapter. (c) Storage...

  8. 24 CFR 266.400 - Property requirements-real estate.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Property requirements-real estate... Mortgage and Closing Requirements; HUD Endorsement § 266.400 Property requirements—real estate. The mortgage must be on real estate held: (a) In fee simple; (b) Under a renewable lease of not less than...

  9. 40 CFR 266.70 - Applicability and requirements.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FACILITIES Recyclable Materials Utilized for Precious Metal Recovery § 266.70 Applicability and... economically significant amounts of gold, silver, platinum, palladium, iridium, osmium, rhodium, ruthenium, or... to or imported from designated OECD member countries for recovery, subpart H of part 262 and §...

  10. 24 CFR 266.115 - Program monitoring and evaluation.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Program monitoring and evaluation... Housing Finance Agency Requirements § 266.115 Program monitoring and evaluation. (a) HFA certifications... and evaluation. Monitoring and evaluation activities will focus on compliance with...

  11. 24 CFR 266.100 - Qualified housing finance agency (HFA).

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Qualified housing finance agency... AUTHORITIES HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Housing Finance Agency Requirements § 266.100 Qualified housing finance agency (HFA). (a)...

  12. [Effects of decitabine on biological behavior of U266 cells].

    Science.gov (United States)

    Wang, Mei-Fang; Yang, Lin-Hua; Dong, Chun-Xia; Zhang, Rui-Juan; Zhang, Jian-Hua; Guo, Zhi-Ping; Chen, Jian-Fang; Zhagn, Li; Feng, Da-Wei

    2011-08-01

    This study was aimed to explore the effects of decitabine on the biological behaviour of U266 cells in vitro so as to provide a new thinking and experiment basis, as well as new evidences for the pathogenesis of multiple myeloma. MTT and colony formation assays were used to evaluate the impact of decitabine on the ability of proliferation of U266 cells; flow cytometry was used to analyze the cell distribution in cell cycle; transwell chamber and matrigel assays were used to observe the ability of migration and invasion. The results indicated that decitabine could significantly suppress the proliferation of U266 cells in time-and dose-dependent manners. The flow cytometric analysis demonstrated that the cells in G(0)-G(1) phase significantly increased while the cells in S and G(2)/M phase decreased. The migration and matrigel invading tests showed that the number of cells moving into under chamber of transwell decreased after U266 cells treated with decitabine. It is concluded that decitabine may act as an effective drug for MM by inhibiting the proliferation, migration and invasion ability, and the specific mechanism needs to be deeply explored.

  13. Photofragment translational spectroscopy of iodobenzene at 266 nm

    Institute of Scientific and Technical Information of China (English)

    张宏; 朱荣顺; 王光俊; 孙巨龙; 韩克利; 何国钟; 楼南泉

    1999-01-01

    The photofragmentation of C6 H5I at 266 nm is investigated on the nuiversal crossed molecular beam machine, and the translational spectroseopy as well as the angular distribution of I atom is measured. The results reveal that under the laser intensity of 108 W/cm2 the single-phuton dissociation competes with multi-photon processes. In singlephoton dissociation the anisotropy parameter β is 0.4 and the average translational energy is only 1.04 keal/mol, which indicates that this process is a slow predissociation. In two-photon phutofragmentation the average translational energy is 51.64 kcal/mol, which accounts for about 35% of the available energy. Another photofragmentation channel is even more faster, whose peak in time-of-flight spectra corresponds to four or five photon absorptions. The branching ratio of these three channels is determined to be about 3: 3: 4.

  14. 24 CFR 266.608 - Mortgage insurance premium: Pro rata refund.

    Science.gov (United States)

    2010-04-01

    ... rata refund. 266.608 Section 266.608 Housing and Urban Development Regulations Relating to Housing and... premium: Pro rata refund. If the Contract of Insurance is terminated by payment in full or is terminated... account. In computing the pro rata portion of the annual mortgage insurance premium, the date...

  15. 40 CFR 266.205 - Standards applicable to the storage of solid waste military munitions.

    Science.gov (United States)

    2010-07-01

    ... solid waste military munitions. 266.205 Section 266.205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS... applicable to the storage of solid waste military munitions. (a) Criteria for hazardous waste regulation...

  16. 40 CFR 266.203 - Standards applicable to the transportation of solid waste military munitions.

    Science.gov (United States)

    2010-07-01

    ... transportation of solid waste military munitions. 266.203 Section 266.203 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS... applicable to the transportation of solid waste military munitions. (a) Criteria for hazardous...

  17. 10 CFR 431.266 - Energy conservation standards and their effective dates.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Energy conservation standards and their effective dates. 431.266 Section 431.266 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL EQUIPMENT Commercial Prerinse Spray Valves Energy Conservation...

  18. Efficient 266 nm Ultraviolet Beam Generation in K2Al2B2O7 Crystal

    Institute of Scientific and Technical Information of China (English)

    吕军华; 王桂玲; 许祖彦; 陈创天; 王继扬; 张承乾; 刘耀岗

    2002-01-01

    The ultraviolet beam at 266 nm was obtained by fourth harmonic generation of 1064 nm Nd:YAG laser radiation through a nonlinear crystal K2Al2 B2O7 (KABO). The fundamental frequency of a Hash-lamp pumped Nd: YAG laser was doubled in a β-Ba2B2O4 crystal to generate a second harmonic output at the wavelength of 532 nm,and then doubled again in the KABO crystal to generate the fourth harmonic output at 266 nm. The optical conversion efficiency from 532 to 266 nm was investigated for the first time, and 13% was achieved.

  19. Compact all-solid-state 266 nm pulse laser%紧凑型全固态266 nm脉冲激光器

    Institute of Scientific and Technical Information of China (English)

    张辰; 高兰兰; 邵志强

    2014-01-01

    报道了利用激光二极管端面抽运Nd ∶YAG晶体,通过Cr4+∶YAG晶体可饱和吸收被动调Q,KTP晶体腔外倍频及BBO晶体腔外四倍频,实现266 nm连续脉冲输出。简要分析了被动调Q基本原理,计算并模拟了1064 nm基频光在理想状态下Cr4+∶YAG晶体不同初始透过率对脉冲激光单脉冲能量的影响。LD抽运功率为4.8 W时,得到266 nm紫外激光平均输出功率为5.63 mW,单脉冲能量约为0.5μJ。在紧凑型毫瓦级266 nm激光器实用化方面取得了一定进展。%266 nm ultraviolet pulse laser is achieved by KTP crystal extra-cavity frequency doubling and BBO crystal extra-cavity frequency quadrupling of a laser in Nd ∶YAG end-pumped by LD and passively Q-switched by Cr4+∶YAG.The basic principle of passively Q-switched is analyzed,and the influence of the initial transmission of the Cr4+∶YAG on single pulse energy of the 1 064nm laser under the ideal condition is calculated and simulated.When the pump power is 4.8W,the output power of 5.63mW and single pulse energy of 0.5μJ at 266 nm laser is ob-tained.Certain progress of practicability of compact milliwatt levels 266nm laser has been made.

  20. Study on a practical 266 nm ultraviolet laser%实用化266nm紫外激光器的研究

    Institute of Scientific and Technical Information of China (English)

    赵书云; 肖磊; 王旭; 张弛; 刘磊

    2012-01-01

    An acousto-optic Q-switched 1064 nm quasi-continuous laser with a LD end-pumped Nd: YVO4 crystal is reported. A LBO crystal and a BBO crystal are respectively used in the cavity for intracavity frequency doubling and ext-racavity frequency quadrupling. A 266 nm ultraviolet laser output with a pulse width of 22 ns, a repetition of 20 kHz and an average power of 1. 12 W is obtained. And the optical-optical efficiency is 21. 37%.%报道了LD端面泵浦Nd∶ YVO4晶体、声光调Q 1064 nm准连续紫外激光,采用LBO晶体和BBO晶体分别进行腔内二倍频和腔外四倍频,从而获得266 nm紫外激光输出,脉冲宽度22 ns、重复频率为20 kHz、平均功率1.12W,光-光转换效率(532 ~266 nm)21.37%.

  1. 40 CFR 266.108 - Small quantity on-site burner exemption.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.108... burn hazardous waste in an on-site boiler or industrial furnace are exempt from the requirements of... boiler or industrial furnace exempt under this section, the quantity limits provided by paragraph...

  2. 29 CFR 500.266 - Responsibility of the Office of Administrative Law Judges.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Responsibility of the Office of Administrative Law Judges... Proceedings Modification Or Vacation of Order of Administrative Law Judge § 500.266 Responsibility of the Office of Administrative Law Judges. Upon receipt of the Secretary's Notice of Intent to Modify or...

  3. Chandra and XMM–Newton Observations of H2O Maser Galaxy Mrk 266

    Indian Academy of Sciences (India)

    J. Wang; J. S. Zhang; J. H. Fan

    2011-03-01

    For H2O megamaser galaxy Mrk 266, its Chandra and XMM–Newton data are analyzed here. It shows existence of two obscured nuclei (separation is ∼ 5''). Our preferred model, the high energy reflected model can fit the hard component of both nuclei spectra well.

  4. 26 CFR 1.401(a)(26)-6 - Excludable employees.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Excludable employees. 1.401(a)(26)-6 Section 1... Excludable employees. (a) In general. For purposes of applying section 401(a)(26) with respect to either employees, former employees, or both employees and former employees, as applicable, all employees other...

  5. 40 CFR Appendix III to Part 266 - Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride III Appendix III to Part 266 Protection of Environment... to Part 266—Tier II Emission Rate Screening Limits for Free Chlorine and Hydrogen Chloride...

  6. Fabrication and stability of fiber bragg gratings for WDM applications using a 266 nm cw-laser

    DEFF Research Database (Denmark)

    Deyerl, Hans-Jürgen; Sørensen, Henrik Rokkjær; Jensen, Jesper Bo Damm

    2003-01-01

    Diode pumped continuous wave all solid state UV-lasers operating at 266 nm offer an interesting alternative to frequency doubled argon ion lasers. We compare photosensitivity, UV-writing of Bragg gratings and thermal decay at 244, 257 and 266 nm....

  7. NF-Kβ Activation in U266 Cells on Mesenchymal Stem Cells

    Science.gov (United States)

    Zahedi, Sara; Shamsasenjan, Karim; Movassaghpour, Aliakbar; Akbarzadehlaleh, Parvin

    2016-01-01

    Purpose: Mesenchymal Stem Cells (MSCs) are one of the essential members of Bone Marrow (BM) microenvironment and the cells affect normal and malignant cells in BM milieu. One of the most important hematological malignancies is Multiple Myeloma (MM). Numerous studies reported various effects of MSCs on myeloma cells. MSCs initiate various signaling pathways in myeloma cells, particularly NF-kβ. NF-kβ signaling pathway plays pivotal role in the survival, proliferation and resistance of myeloma cells to the anticancer drugs, therefore this pathway can be said to be a vital target for cancer therapy. This study examined the relationship between U266 cells and MSCs. Methods: U266 cells were cultured with Umbilical Cord Blood derived-MSCs (UCB-MSCs) and Conditioned Medium (C.M). Effect of UCB-MSCs and C.M on proliferation rate and CD54 expression of U266 cells were examined with MTT assay and Flowcytometry respectively. Furthermore, expression of CXCL1, PECAM-1, JUNB, CCL2, CD44, CCL4, IL-6, and IL-8 were analyzed by Real Time-PCR (RT-PCR). Moreover, status of p65 protein in NF-kβ pathway assessed by western blotting. Results: Our findings confirm that UCB-MSCs support U266 cells proliferation and they increase CD54 expression. In addition, we demonstrate that UCB-MSCs alter the expression of CCL4, IL-6, IL-8, CXCL1 and the levels of phosphorylated p65 in U266 cells. Conclusion: Our study provides a novel sight to the role of MSCs in the activation of NF-kβ signaling pathway. So, NF-kβ signaling pathway will be targeted in future therapies against MM.

  8. Characterization of the Cysteine Content in Proteins Utilizing Cysteine Selenylation with 266 nm Ultraviolet Photodissociation (UVPD)

    Science.gov (United States)

    Parker, W. Ryan; Brodbelt, Jennifer S.

    2016-08-01

    Characterization of the cysteine content of proteins is a key aspect of proteomics. By defining both the total number of cysteines and their bound/unbound state, the number of candidate proteins considered in database searches is significantly constrained. Herein we present a methodology that utilizes 266 nm UVPD to count the number of free and bound cysteines in intact proteins. In order to attain this goal, proteins were derivatized with N-(phenylseleno)phthalimide (NPSP) to install a selectively cleavable Se-S bond upon 266 UVPD. The number of Se-S bonds cleaved upon UVPD, a process that releases SePh moieties, corresponds to the number of cysteine residues per protein.

  9. 1.9-W flash-lamp-pumped solid-state 266-nm ultraviolet laser

    Institute of Scientific and Technical Information of China (English)

    Zhen Xiang; Jianhong Ge; Zhigang Zhao; Sha Wang; Chong Liu; Jun Chen

    2009-01-01

    Deep ultraviolet lasers have various applications in industries and scientific researches.For 266-nrn ultraviolet (UV) laser generation,the good beam quality of 1064-nm laser and the elimination of gray-tracking effect of KTP crystal are two key factors.Using a dynamically stable resonator design,1064-nnl laser with an average power of 52 W is realized with repetition rate of 16 kHz.The measured M2 factor characterizing the beam quality is 1.5.By the elimination of gray-tracking effect of KTP crystal,an 18-W green laser is realized with the M2 factor of 1.6.Using a BBO crystal for tire fourth harmonic generation,a 1.9-W 266-nm UV laser is achieved.

  10. 40 CFR Appendix Xii to Part 266 - Nickel or Chromium-Bearing Materials that may be Processed in Exempt Nickel-Chromium Recovery...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Nickel or Chromium-Bearing Materials that may be Processed in Exempt Nickel-Chromium Recovery Furnaces XII Appendix XII to Part 266... FACILITIES Pt. 266, App. XII Appendix XII to Part 266—Nickel or Chromium-Bearing Materials that may...

  11. 40 CFR Appendix Xi to Part 266 - Lead-Bearing Materials That May be Processed in Exempt Lead Smelters

    Science.gov (United States)

    2010-07-01

    ... WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Pt. 266, App. XI Appendix XI to Part... Pasting additive bags Asphalt paving materials B. Exempt Lead-Bearing Materials When Generated...

  12. Skyrme forces and decay of the Rf266*104 nucleus synthesized via different incoming channels

    Science.gov (United States)

    Niyti, Deep, Aman; Kharab, Rajesh; Chopra, Sahila; Gupta, Raj K.

    2017-03-01

    The excitation functions for the production of 262Rf, 261Rf, and 260Rf isotopes via 4 n -, 5 n -, and 6 n -decay channels from the *266Rf compound nucleus are studied within the dynamical cluster-decay model (DCM), including deformations β2 i and so-called hot-optimum orientations θi which support symmetric fission, in agreement with experiments. The data are available for 18O+248Cm and 22Ne+244Pu reactions, respectively, at the energy ranges of Elab=88.2 to 101.3 and 109.0 to 124.8 MeV. For the nuclear interaction potentials, we use the Skyrme energy density functional (SEDF) based on semiclassical extended Thomas Fermi (ETF) approach, which means an extension of the earlier study of excitation functions of *266Rf formed in 18O+248Cm reaction, based on the DCM using the pocket formula for nuclear proximity potential, showing interaction dependence. The Skyrme forces used here are the old SIII and SIV and new GSkI and KDE0(v1) given for both normal and isospin-rich nuclei, with densities added in frozen density approximation. Interestingly, the DCM gives an excellent fit to the measured data on fusion evaporation residue (ER) for both the incoming channels (18O+248Cm and 22Ne+244Pu ) at the energy range Elab=88.2 to 124.8 MeV, independent of the entrance channel and Skyrme force used. The possible fusion-fission (ff) and quasifission (qf) mass regions of fragments on DCM are also predicted. The DCM with Skyrme forces is further used to look for all the possible target-projectile (t-p) combinations forming the cold compound nucleus (CN) *266Rf at the CN excitation energy of Elab for hot compact configurations. The fusion evaporation residue cross sections, for the proposed new reactions in synthesizing the CN *266Rf, are also estimated for the future experiments, and role of mass asymmetry of nuclei is indicated.

  13. 细菌性脑炎/脑膜炎266例流行病学分析%Epidemic Analysis of 266 Cases With Bacterial Meningitis or Encephalitis

    Institute of Scientific and Technical Information of China (English)

    李静; 张振国; 孙印旗; 郭建花; 甄素娟; 王颖童; 贾肇一; 尹遵栋

    2012-01-01

    Objective To provide scientific evidence for the similar nationwide study by understanding the epidemic characteristics and pathogeny spectrum of bacterial meningitis and encephalitis. Methods Cases with bacterial meningitis and encephalitis were investigated, with the blood samples and/ or CSF samples from surveillance cases were collected for laboratory testing. Results From the May, 2007 to December, 2010, 266 cases was reported and investigated. The male - to - female ratio was 1. 56 : 1, the average age of cases was 8. 7 years old, and 73. 7% of cases were children under 10 years old. Cases occurred all the year round, with no obvious seasonal peak. 19. 9% of cases had been vaccinated at least one of vaccines among encephalitis vaccine , meningococcal vaccine and rlib vaccine. 92.4% of cases used the antibiotics before the collection of samples. The main bacterial pathogeny spectrum of laboratory - confirmed bacterial meningitis/encephalitis cases were Streptococcus pneumoniae, Cryptococcus neoformans, Neisseria catarrhalis and Hib. Conclusion The epidemic characteristics and pathogeny spectrum is preliminary understood. It may provide the experience for the national surveillance of bacterial meningitis or encephalitis and other syndrome.%目的 了解急性细菌性脑炎/脑膜脑炎的流行特征与病原谱,为全国范围内开展类似研究提供科学依据.方法 对监测到的细菌性脑炎/脑膜炎开展个案调查并采集血清和或脑脊液标本,开展实验室检测工作.结果 2007 - 05/2010 -12报告的出院诊断为细菌性脑炎/脑膜脑炎患者266例,男女性别比为1.56∶1,平均年龄8.7岁,73.7%的病例集中在10岁以下儿童,各月都有病例发生,无明显发病季节高峰.19.9%病例接种过乙脑、流脑、Hib疫苗中的一种或一种以上,92.4%的病例在标本采集前使用了抗生素.实验室确诊的细菌性脑炎/脑膜脑炎病例的主要病原为肺炎链球菌、脑膜炎奈瑟菌、新

  14. 地西他滨对多发性骨髓瘤U266细胞株生物学行为的影响%Effects of Decitabine on Biological Behavior of U266 Cells

    Institute of Scientific and Technical Information of China (English)

    王梅芳; 杨林花; 董春霞; 张睿娟; 张建华; 郭志萍; 陈剑芳; 张丽; 冯大伟

    2011-01-01

    This study was aimed to explore the effects of decitabine on the biological behaviour of U266 cellsin vitro so as to provide a new thinking and experiment basis, as well as new evidences for the pathogenesis of multiple myeloma. MIT and colony formation assays were used to evaluate the impact of decitabine on the ability of proliferation of U266 cells; flow cytometry was used to analyze the cell distribution in cell cycle; transwell chamber and matrigel assays were used to observe the ability of migration and invasion. The results indicated that decitabine could significantly suppress the proliferation of U266 cells in time- and dose-dependent manners. The flow cytometric analysis demonstrated that the cells in G0 - G1 phase significantly increased while the cells in S and G2/M phase decreased. The migration and matrigel invasing tests showed that the number of cells moving into under chamber of transwell decreased after U266 cells treated with decitabine. It is concluded that decitabine may act ns an effective drug for MM by inhibiting the proliferation, migration and invasion ability, and the specific mechansim needs to be deeply explored.%本研究以多发性骨髓瘤U266细胞株为实验对象,探讨地西他滨对其生物学功能的影响,为MM的临床治疗提供新思路及实验依据,也为MM的发病机制提供进一步的佐证.应用MTT实验、平板克隆形成试验、FCM分析细胞周期、transwell迁移及matrigel侵袭试验分别检测地西他滨对U266细胞增殖、迁移及侵袭能力的影响.结果表明,地西他滨随着浓度增加对U266细胞增殖抑制作用增强,呈剂量和时间依赖性;FCM检测结果表明地西他滨处理后,G0-G1期U266细胞明显增加,S期和G2-M期细胞降低(p<0.05),表明地西他滨可抑制U266细胞DNA合成,将细胞周期阻滞在G0-G1期;低浓度(0.8 mmol/L)地西他滨处理后U266细胞迁移能力及侵袭力明显降低(p<0.05).结论:地西他滨对U266细胞的增殖、迁移

  15. 安徽耕地面积增加266万亩

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    在城市化进程如火如荼,农村外出务工人员比率居高不下的时候,耕地面积增加释放了怎样的信号?安徽省第二次土地调查数据成果发布,安徽省总面积1401.475公顷(21021万亩),其中耕地面积590.71万公顷(8860.6万亩),比第一次土地调查增加17.75万公顷(266.2万亩)。

  16. Signature of Plausible Accreting Supermassive Black Holes in Mrk 261/262 and Mrk 266

    Directory of Open Access Journals (Sweden)

    Gagik Ter-Kazarian

    2013-01-01

    Full Text Available We address the neutrino radiation of plausible accreting supermassive black holes closely linking to the 5 nuclear components of galaxy samples of Mrk 261/262 and Mrk 266. We predict a time delay before neutrino emission of the same scale as the age of the Universe. The ultrahigh energy neutrinos are produced in superdense protomatter medium via simple (quark or pionic reactions or modified URCA processes (G. Gamow was inspired to name the process URCA after the name of a casino in Rio de Janeiro. The resulting neutrino fluxes for quark reactions are ranging from to , where is the opening parameter. For pionic and modified URCA reactions, the fluxes are and , respectively. These fluxes are highly beamed along the plane of accretion disk, peaked at ultrahigh energies, and collimated in smaller opening angle .

  17. Refractive index-modified structures in glass written by 266nm fs laser pulses.

    Science.gov (United States)

    Saliminia, Ali; Bérubé, Jean-Philippe; Vallée, Réal

    2012-12-03

    We demonstrate the inscription of embedded waveguides, anti-waveguides and Bragg gratings by use of intense femtosecond (fs) UV laser pulses at 266nm in pure fused silica, and for the first time, in bulk fused quartz and ZBLAN glasses. The magnitude of induced index changes, depends, besides pulse energy and translation speed, largely on writing depth and varies from ~10(-4) for smooth modifications to ~10(-3) for damaged structures. The obtained results are promising as they present the feasibility of fabrication of short (< 0.2μm) period first-order fiber Bragg gratings (FBGs) for applications such as in realization of all-fiber lasers operating at short wavelengths.

  18. Inhomogeneous magnetism in the doped kagome lattice of LaCuO2.66

    Energy Technology Data Exchange (ETDEWEB)

    Julien, M.-H. [Laboratoire National des Champs Magn´etiques Intenses; Simonet, V [Institut Neel, CNRS-UJF; Canals, B. [Institut Neel, CNRS-UJF; Garlea, Vasile O [ORNL; Bordet, Pierre [Laboratoire of Cristallographie, Grenoble; Darie, Celine [Laboratoire of Cristallographie, Grenoble

    2013-01-01

    The hole-doped kagome lattice of Cu2+ ions in LaCuO2.66 was investigated by nuclear quadrupole resonance (NQR), electron spin resonance (ESR), electrical resistivity, bulk magnetization and specific heat measurements. For temperatures above 180 K, the spin and charge properties show an activated behavior suggestive of a narrow-gap semiconductor. At lower temperatures, the results indicate an insulating ground state which may or may not be charge ordered. While the frustrated spins in remaining patches of the original kagome lattice might not be directly detected here, the observation of coexisting non-magnetic sites, free spins and frozen moments reveals an intrinsically inhomogeneous magnetism. Numerical simulations of a 1/3-diluted kagome lattice rationalize this magnetic state in terms of a heterogeneous distribution of cluster sizes and morphologies near the site-percolation threshold.

  19. 白桦脂酸联合沙利度胺诱导U266细胞凋亡机制研究%Research on Betulinic Acid Combined with Thalidomide Induce Apoptosis of U266 Cells and Its Mechanism

    Institute of Scientific and Technical Information of China (English)

    孙嘉; 马丹; 王萍; 方琴

    2015-01-01

    Objective:To investigate the betulinic acid combined with Thalidomide induce apoptosis of U266 cells and its mechanism. Methods:U266 cells were treated with betulinic acid(20,40,60 and 80 mg/L,betulinic acid group ),Thalidomide( 10 mg/L,50 mg/L,100 mg/L,Thalidomide group)and betulinic acid(40 mg/L)combined with Thalidomide( betulinic acid 40 mg/L,10,50 and 100 mg/L of Thalidomide,combined group)coupled with control group. Proliferation inhibition rate and apoptosis rate of U266 cells from different concentrations were detected with MTT and flow cy-tometry;Real-time PCR was used to detect the expression levels of Survivin,Cyto-C,Bcl-2,Bax gene. Western blotting was used to detect the expression of Survivin,Cyto-C,Bcl-2,Bax protein. Re-sults:With the increase of betulinic acid concentration,inhibition rate of U266 cells was also in-creased,differences were statistically significant( P <0. 05),the most appropriate concentration was 40 mg/L ;comparing with Thalidomide,inhibition rate and apoptosis rate of U266 cells were obviously increased,differences were statistically significant(P<0. 05);comparing with Thalidomide group or betulinic acid group,Survivin and expression of Bcl-2 mRNA of U2666 cells obviously decreased,Cy-to-C and expression of Bax mRNA obviously increased,differences were statistically significant(P<0. 05 ). Conclusion:The betulinic acid combined with thalidomide induce apoptosis of multiple myeloma U266 cells and its mechanism may be correlated with the proapoptotic molecule of survivin,Bcl-2,Cy-to-c and Bax.%目的:探讨白桦脂酸联合沙利度胺诱导多发性骨髓瘤( MM)U266细胞凋亡的机制。方法:分别用白桦脂酸(20、40、60和80 mg/L,白桦脂酸组)、沙利度胺(10、50和100 mg/L,沙利度胺组)及白桦脂酸(40 mg/L)联合沙利度胺(联合组,白桦脂酸40 mg/L,沙利度胺10、50和100 mg/L)分别处理U266细胞,同期设对照组;MTT法和流式细胞术分别检测不同浓

  20. The effect of peptidoglycan on cell proliferation in multiple myeloma U266 cell line%肽聚葡糖对多发性骨髓瘤U266细胞株增殖的影响

    Institute of Scientific and Technical Information of China (English)

    何丽梅; 李智; 许闪闪

    2011-01-01

    Objective To investigate the effect of peptidoglycan ( PGN) on cell proliferation in multiple myeloma(MM) cell line. Methods The mRNA levels of TLR2, IL-1β (5, IL-8, NF-κB , Stat3 and TNF were measured by fluorescence quantitative polymerase chain reaction (PCR) in MM U266 cells and the peripheral blood mononuclear cells(PBMCs) of 23 healthy individuals. After U266 cells were cultured with 20μg/ml PGN, the mRNA of TLR2 and NF-κB was analyzed by PCR; and the NF-kB protein was evaluated by Western blotting. In addition, the cell proliferation and cell cycle were analyzed by MTT and Flow cytometry (FCM), respectively. Results Compared with PBMCs, the expressions of TLR2, IL-8, TNF decreased in U266, while the expression of NF-κB increased (P < 0.05). After treated with PGN, the mRNA level of TLR2 and NF-κB increased, and the expression of NF-kB protein also increased; G0/G1 phase was propelled and cell mitosis and proliferation were increased. Conclusion PGN may promote cell proliferation in U266 by activating the NF-kB pathway.%目的 研究浆细胞异常增生的多发性骨髓瘤( multiple myeloma,MM)细胞在受到肽聚葡糖(peptidoglycan,PGN)刺激后对细胞增殖的影响.方法 利用荧光定量聚合酶链反应(PCR)分析MM U266细胞株TLR2、IL-1β、IL-8、NF-κB、Stat3和TNF蛋白的mRNA水平,与23名正常人单个核细胞(peripheral blood mononuclear cells,PBMCs)mRNA比较.20μg/ml PGN与U266细胞共培养,分析TLR2和NF-κB蛋白mRNA的变化情况.Western印迹法检测该药对U266细胞NF-κB蛋白的影响.MTT、流式细胞术检测PGN刺激U266后增殖情况.结果 与PBMCs相比,TLR2、IL-8、TNF在U266中表达显著降低,而NF-κB表达增加(P<0.05).经PGN作用后,TLR2、NF-κB mRNA表达均增加,Western印迹法检测NF-κB蛋白表达明显增多.MTT及细胞周期检测发现,PGN可使细胞由G0/G1期向前推进,促进细胞有丝分裂及增殖.结论 PGN可能通过激活NF-κB通路促进U266增殖.

  1. 76 FR 13354 - Foreign-Trade Zone 266-Dane County, WI; Application for Subzone, Cabela's Inc. (Hunting, Fishing...

    Science.gov (United States)

    2011-03-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 266--Dane County, WI; Application for Subzone, Cabela's Inc. (Hunting, Fishing, Camping and Related Outdoor Merchandise), Prairie du Chien, WI An application has...

  2. 40 CFR 266.107 - Standards to control hydrogen chloride (HCl) and chlorine gas (Cl2) emissions.

    Science.gov (United States)

    2010-07-01

    ... Industrial Furnaces § 266.107 Standards to control hydrogen chloride (HCl) and chlorine gas (Cl2) emissions... other thermal treatment unit subject to controls on HCl or Cl2 emissions under a RCRA operating permit... risk assessments—(1) General. Conformance with the Tier III controls must be demonstrated by...

  3. Residue Phe266 in S5-S6 loop is not critical for Charybdotoxin binding to Ca2+-activated K+ (mSlo1) channels

    Institute of Scientific and Technical Information of China (English)

    Jing YAO; Hui LI; Ge-liang GAN; Ying WU; Jiu-ping DING

    2006-01-01

    Aim: To gain insight into the interaction between the Charybdotoxin (ChTX) and BK channels. Methods: Site-directed mutagenesis was used to make two mutants: mSlo1-F266L and mSlo1-F266A. The two mutants were then expressed in Xeno-pus oocytes and their effects were tested on ChTX by electrophysiology experiments. Results: We demonstrate an equilibrium dissociation constant Kd= 3.1-4.2 nmol/L for both the mutants mSlo1-F266L and mSlo1-F266A similar to that of the wild-type mSlo1 Kd=3.9 nmol/L. Conclusion: The residue Phe266 does not play a crucial role in binding to ChTX, which is opposed to the result arising from the simulation of peptide-channel interaction.

  4. The photochemistry of [Fe(III)N3(cyclam-ac)]PF6 at 266 nm.

    Science.gov (United States)

    Torres-Alacan, Joel; Krahe, Oliver; Filippou, Alexander C; Neese, Frank; Schwarzer, Dirk; Vöhringer, Peter

    2012-03-01

    The photochemistry of iron azido complexes is quite challenging and poorly understood. For example, the photochemical decomposition of [Fe(III)N(3)(cyclam-ac)]PF(6) ([1]PF(6)), where cyclam-ac represents the 1,4,8,11-tetraazacyclotetradecane-1-acetate ligand, has been shown to be wavelength-dependent, leading either to the rare high-valent iron(V) nitrido complex [Fe(V)N(cyclam-ac)]PF(6) ([3]PF(6)) after cleavage of the azide N(α)-N(β) bond, or to a photoreduced Fe(II) species after Fe-N(azide) bond homolysis. The mechanistic details of this intriguing reactivity have never been studied in detail. Here, the photochemistry of 1 in acetonitrile solution at room temperature has been investigated using step-scan and rapid-scan time-resolved Fourier transform infrared (FTIR) spectroscopy following a 266 nm, 10 ns pulsed laser excitation. Using carbon monoxide as a quencher for the primary iron-containing photochemical product, it is shown that 266 nm excitation of 1 results exclusively in the cleavage of the Fe-N(azide) bond, as was suspected from earlier steady-state irradiation studies. In argon-purged solutions of [1]PF(6), the solvent-stabilized complex cation [Fe(II)(CH(3)CN)(cyclam-ac)](+) (2red) together with the azide radical (N(3)(.)) is formed with a relative yield of 80%, as evidenced by the appearance of their characteristic vibrational resonances. Strikingly, step-scan experiments with a higher time resolution reveal the formation of azide anions (N(3)(-)) during the first 500 ns after photolysis, with a yield of 20%. These azide ions can subsequently react thermally with 2red to form [Fe(II)N(3)(cyclam-ac)] (1red) as a secondary product of the photochemical decomposition of 1. Molecular oxygen was further used to quench 1red and 2red to form what seems to be the elusive complex [Fe(O(2))(cyclam-ac)](+) (6).

  5. Temperature and bath gas composition dependence of effective fluorescence lifetimes of toluene excited at 266 nm

    Science.gov (United States)

    Faust, S.; Dreier, T.; Schulz, C.

    2011-05-01

    Time-resolved fluorescence spectra of gas-phase toluene upon picosecond excitation at 266 nm were investigated as a function of temperature (296-1074 K) and bath gas composition (varying amounts of N 2, O 2, and CO 2) at 1 bar total pressure with a temporal resolution of 50 ps. In the investigated temperature range the effective fluorescence lifetime drops with increasing temperature from 46 ± 3 ns to 0.05 ± 0.01 ns in N 2 and CO 2. In the presence of O 2 at constant temperature the lifetimes also decrease significantly (e.g., from 46 ± 3 ns without O 2 to 0.63 ± 0.05 ns in air at room temperature), whereas lifetimes are independent on the CO 2 concentration. The implications of the results for the existing phenomenological model of predicting temporally integrated fluorescence intensities in toluene [W. Koban, J.D. Koch, R.K. Hanson, C. Schulz, Appl. Phys. B 80 (2005) 777] are discussed.

  6. Generation of 266 nm continuous-wave with elliptical Gaussian b eams%利用椭圆高斯光束产生266 nm紫外连续激光

    Institute of Scientific and Technical Information of China (English)

    陈国柱; 沈咏; 刘曲; 邹宏新

    2014-01-01

    The 266 nm continuous-wave coherent radiation is generated by the second harmonic generation of aβ-BBO crystal placed inside an external enhancement cavity. Its fundamental beam is a 532 nm laser from commercial production of Coherent Company. Impact of focusing shape of the crystal on the conversion efficiency is simulated detailedly. Theoretical and experimental results show that the elliptical focusing can decrease the walk-off effect and improve conversion efficiency of the second harmonic generation (SHG). We obtain experimentally the 266 nm radiation output of 180 mW with elliptical focusing in a BBO crystal using bowtie cavity when the fundamental wave input 1 W . The SHG conversion efficiency reaches 18%.%本文采用商用532 nm激光器作为基频光源,利用偏硼酸钡(β-BBO)晶体进行外腔倍频,实现了266 nm连续激光的高效输出。文中详细模拟了BBO晶体中的束腰形状对倍频效率的影响,仿真和实验结果均表明椭圆高斯光束可以有效改善走离效应,提高倍频转换效率。通过优化蝶形倍频腔,可以使椭圆高斯光束在腔内共振,当1 W基频光输入时可输出约180 mW的266 nm紫外连续激光,倍频转换效率达到18%。

  7. Yb-fiber-laser-based, 1.8 W average power, picosecond ultraviolet source at 266 nm.

    Science.gov (United States)

    Chaitanya Kumar, S; Canals Casals, J; Sanchez Bautista, E; Devi, K; Ebrahim-Zadeh, M

    2015-05-15

    We report a compact, stable, high-power, picosecond ultraviolet (UV) source at 266 nm based on simple single-pass two-step fourth-harmonic generation (FHG) of a mode-locked Yb-fiber laser at 79.5 MHz in LiB3O5 (LBO) and β-BaB2O4. Using a 30-mm-long LBO crystal for single-pass second-harmonic generation, we achieve up to 9.1 W of average green power at 532 nm for 16.8 W of Yb-fiber power at a conversion efficiency of 54% in 16.2 ps pulses with a TEM00 spatial profile and passive power stability better than 0.5% rms over 16 h. The generated green radiation is then used for single-pass FHG into the UV, providing as much as 1.8 W of average power at 266 nm under the optimum focusing condition in the presence of spatial walk-off, at an overall FHG conversion efficiency of ∼11%. The generated UV output exhibits passive power stability better than 4.6% rms over 1.5 h and beam pointing stability better than 84 μrad over 1 h. The UV output beam has a circularity of >80% in high beam quality with the TEM00 mode profile. To the best of our knowledge, this is the first report of picosecond UV generation at 266 nm at megahertz repetition rates.

  8. Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets

    Science.gov (United States)

    Litou, Zoi I.; Konstandi, Ourania A.; Giannopoulou, Aikaterini F.; Anastasiadou, Ema; Voutsinas, Gerassimos E.; Tsangaris, George Th.; Stravopodis, Dimitrios J.

    2017-01-01

    Cutaneous melanoma is a malignant tumor of skin melanocytes that are pigment-producing cells located in the basal layer (stratum basale) of epidermis. Accumulation of genetic mutations within their oncogenes or tumor-suppressor genes compels melanocytes to aberrant proliferation and spread to distant organs of the body, thereby resulting in severe and/or lethal malignancy. Metastatic melanoma’s heavy mutational load, molecular heterogeneity and resistance to therapy necessitate the development of novel biomarkers and drug-based protocols that target key proteins involved in perpetuation of the disease. To this direction, we have herein employed a nano liquid chromatography-tandem mass spectrometry (nLC-MS/MS) proteomics technology to profile the deep-proteome landscape of WM-266-4 human metastatic melanoma cells. Our advanced melanoma-specific catalogue proved to contain 6,681 unique proteins, which likely constitute the hitherto largest single cell-line-derived proteomic collection of the disease. Through engagement of UNIPROT, DAVID, KEGG, PANTHER, INTACT, CYTOSCAPE, dbEMT and GAD bioinformatics resources, WM-266-4 melanoma proteins were categorized according to their sub-cellular compartmentalization, function and tumorigenicity, and successfully reassembled in molecular networks and interactomes. The obtained data dictate the presence of plastically inter-converted sub-populations of non-cancer and cancer stem cells, and also indicate the oncoproteomic resemblance of melanoma to glioma and lung cancer. Intriguingly, WM-266-4 cells seem to be subjected to both epithelial-to-mesenchymal (EMT) and mesenchymal-to-epithelial (MET) programs, with 1433G and ADT3 proteins being identified in the EMT/MET molecular interface. Oncogenic addiction of WM-266-4 cells to autocrine/paracrine signaling of IL17-, DLL3-, FGF(2/13)- and OSTP-dependent sub-routines suggests their critical contribution to the metastatic melanoma chemotherapeutic refractoriness. Interestingly, the

  9. Epidemiological and clinical characteristics of 266 cases of intracerebral hemorrhage in Hangzhou, China

    Institute of Scientific and Technical Information of China (English)

    Yun-zhen HU; Jian-wen WANG; Ben-yan LUO

    2013-01-01

    Ethnicity and socioeconomic factors can influence disease susceptibility,clinical presentation,and outcome.We investigated the clinical characteristics (age,sex,seasonal variation,lesion site,symptoms,complications,prognosis,and sequelae) and risk factors for intracerebral hemorrhage (ICH) in 266 cases treated at our hospital in Hangzhou City,China,from January 2011 to December 2011.Risk of ICH increased dramatically with age; only 4.3%of cases were <30 years old,while 44.4% were >60 years of age.Men outnumbered women by 2:1 (67.3% vs.32.7%).Single hemorrhage was most often located in the cerebral lobes (37.2% of cases),basal ganglia (34.2%),thalamus (8.3%),cerebellum (6.8%),ventricle (1.5%),and brainstem (1.1%),while 10.9% of cases exhibited hemorrhages at multiple sites.Hypertension was also a major risk factor for ICH,as 47% of all patients were hypertensive and the percentage increased with age.In hypertensive patients,the most common hemorrhage site was the basal ganglia and ICH was often associated with thrombopenia.In patients with leukemia (all forms),most hemorrhages were lobar.Warfarin-and encephalic operation-associated ICHs were all lobar.Headache was the major symptom of occipital,temporal,and frontal lobe hemorrhage.Dizziness,nausea,and vomiting were the major symptoms of cerebellum hemorrhage.Limb dysfunction was the major symptom of thalamic and basal ganglia hemorrhage.Disturbed level of consciousness was the major symptom in multisite,ventricular,parietal lobe,and brainstem hemorrhage.Hyperspasmia occurred most often in lobar hemorrhage and blurred vision in occipital lobe hemorrhage.Hospital mortality was 24.4% (n=65) with a mean delay from presentation to death of (10.5±18.5) d.The majority of fatalities were cerebral hernia cases (58.5%) and these patients also had the shortest time to death [(2.9±3.5) d].Mortality was 100%in brainstem ICH and hemorrhagic conversion of cerebral infarct

  10. 腔镜联合内镜序贯性治疗胆石病266

    Institute of Scientific and Technical Information of China (English)

    陈小勋; 林源; 罗汉传; 李世新; 覃俊仕; 林月双; 吴瑞正; 黄克伟; 张兆明; 莫显伟; 陈培升; 陆声榆

    2007-01-01

    目的 探讨腔镜、十二指肠镜、胆道镜序贯性治疗胆石病的意义.方法 回顾分析采用腔镜、胆道镜、十二指肠镜序贯性治疗胆石病266例的临床资料,其中行腹腔镜胆囊切除术(laparoscopic Cholecystectomy,LC)193例,行十二指肠镜下乳头括约肌囊状扩张术(endoscopic Papillary Balloon Delation,EPBD)20例,行十二指肠镜下乳头括约肌切开取石术(endoscopic Spincterotomy,EST)31例,十二指肠镜鼻胆管引流术(endoscopic Nasobiliary Drainage,ENBD)10例,腹腔镜联合纤维胆道镜胆总管切开探查术(laparoscopic Choledocholihotomy and T-tube Drainage,LCTD)29例.结果 LC成功率98.97%(191/193),EPBD成功率80%(16/20),EST成功率90.33%(28/31),ENBD成功率100%(6/6),LCTD成功率93.10%(27/29).全组中转开腹率1.50%(4/266),并发症4.13%(11/266),术后残石4例,经EST或胆道镜成功取石.结论 腔镜联合内镜序贯性治疗胆石病,微创治疗成功率高,术后残石率低,并发症少,值得临床推广使用.

  11. Preparation of BiSrCaCuO Multilayers by Use of Slower Q-switched 266 nm YAG Laser

    Science.gov (United States)

    Kaneko, Satoru; Shimizu, Yoshitada; Ohya, Seishiro

    2001-08-01

    Multilayers of Bi2Sr2Ca1Cu2Ox{\\slash}Bi2Sr2Cu1Ox were prepared by pulsed laser deposition (PLD) using the fourth harmonic 266 nm YAG. Compared to an excimer laser, YAG PLD required the higher oxygen atmosphere. The higher oxygen pressure together with the lower energy generated by YAG laser collapsed the region of plume emission. In order to produce the same energy density as an excimer, only Q-switch was modulated by 2 Hz while the flash lamp kept the original repetition rate of 10 Hz. With the rate of 2 Hz, we obtained the higher energy density per pulse, and more stable laser output of the fourth harmonics, 266 nm. To characterize the multilayers, reflection high-energy electron diffraction (RHEED) and X-ray diffraction (XRD) were employed, and indicative of epitaxial layers with limited in-plane order. The resistivities of multilayers were measured by the Van der Pauw method, and showed the temperatures of superconducting transition, Tc0 (R=0), around 65 K on the multilayers.

  12. Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells

    Directory of Open Access Journals (Sweden)

    Allouche Stéphane

    2009-06-01

    Full Text Available Abstract Background opioid and somatostatin receptors (SSTRs that can assemble as heterodimer were individually reported to modulate malignant cell proliferation and to favour apoptosis. Materials and methods: SSTRs and opioid receptors expression were examined by RT-PCR, western-blot and binding assays, cell proliferation was studied by XTT assay and propidium iodide (PI staining and apoptosis by annexin V-PI labelling. Results almost all human malignant haematological cell lines studied here expressed the five SSTRs. Further experiments were conducted on the human U266 multiple myeloma cells, which express also μ-opioid receptors (MOP-R. XTT assays and cell cycle studies provide no evidence for a significant effect upon opioid or somatostatin receptors stimulation. Furthermore, neither direct effect nor potentiation of the Fas-receptor pathway was detected on apoptosis after these treatments. Conclusion these data suggest that SSTRs or opioid receptors expression is not a guaranty for an anti-tumoral action in U266 cell line.

  13. On the Expansion Rate, Age, and Distance of the Supernova Remnant G266.2-1.2 (Vela Jr.)

    CERN Document Server

    Allen, G E; DeLaney, T; Filipovic, M D; Houck, J C; Pannuti, T G; Stage, M D

    2014-01-01

    An analysis of Chandra ACIS data for two relatively bright and narrow portions of the northwestern rim of G266.2-1.2 (a.k.a. RX J0852.0-4622 or Vela Jr.) reveal evidence of a radial displacement of 2.40 +/- 0.56 arcsec between 2003 and 2008. The corresponding expansion rate (0.42 +/- 0.10 arcsec/yr or 13.6 +/- 4.2%/kyr) is about half the rate reported for an analysis of XMM-Newton data from a similar, but not identical, portion of the rim over a similar, but not identical, time interval (0.84 +/- 0.23 arcsec/yr, Katsuda et al. 2008a). If the Chandra rate is representative of the remnant as a whole, then the results of a hydrodynamic analysis suggest that G266.2-1.2 is between 2.4 and 5.1 kyr old if it is expanding into a uniform ambient medium (whether or not it was produced by a Type Ia or Type II event). If the remnant is expanding into the material shed by a steady stellar wind, then the age could be as much as 50% higher. The Chandra expansion rate and a requirement that the shock speed be greater than or...

  14. Analysis and investigation of 266 suspicious tuberculosis patients with multi-drug resistance%2013年杂志266例可疑耐多药结核病人筛查情况分析与探讨

    Institute of Scientific and Technical Information of China (English)

    樊晖; 刘国标; 吴龙章; 陈剑锋; 何霞

    2013-01-01

    目的 对266例可疑耐多药结核病患者进行耐多药筛查,并对结果分析和探讨.方法通过痰涂片及培养、菌鉴及药敏试验诊断耐多药结核.结果 266例可疑患者耐药发生率53.3%,其中MDR-TB 28.2%,DR-TB 25.1%,MDR-TB复治失败病人比例最高.DR-TB初治3月末阳性比例最高.MDR-TB中,初治组耐HRES、HRS最多,复治组耐HR、HRES最多.结论 复治组是发生MDR-TB主要类别,耐多药筛查可早期发现MDR-TB病人,为制定耐多药结核病防治对策提供参考依据.%Objective To screen the drug resistance of 266 suspicious tuberculosis patients with multi-drag resistance, and to analyze the results. Methods The drug resistance was test through the sputum smear and culture, bacteria identification and drag sensitivity test. Results The incidence of drug resistance was 53. 3% , including 28. 2% of MDR-TB and 25. 1% of DR-TB. The re-treatment failure rate of NDR-TB patients was the highest. At the end of the third month after the initial treatment, the positive rate of DR-TB was the highest. HRES and HRS were found mostly in the initial treatment group of MDR-TB patients, and HR and HRES were found mostly in the re-treatment group. Conclusion The re-treatment group is the main group where MDR-TB occurs. Therefore, the MDR-TB patients can be found in the early stage by the multi-drag resistance screening which can provide the clinical references for the treatment of patients with multi-drag resistance tuberculosis.

  15. Demonstration of long-term reliability of a 266-nm, continuous-wave, frequency-quadrupled solid-state laser using beta-BaB(2)O(4).

    Science.gov (United States)

    Kondo, K; Oka, M; Wada, H; Fukui, T; Umezu, N; Tatsuki, K; Kubota, S

    1998-02-01

    We report what we believe to be the first operation of more than 1000 h of a 266-nm (cw) frequency-quadrupled solid-state laser with a 100-mW output. We used beta-BaB(2)O(4)(BBO) crystal grown by the Czochralski method to double the green-light (532-nm) wavelength, using an external resonant cavity. The green light was generated with an intracavity frequency-doubled Nd:YVO(4)laser pumped by a 4-W laser diode. When the incident 532-nm power on the external resonant doubler was 500 mW, we generated 100 mW of cw 266-nm radiation with the BBO crystal. The degradation rate seems to be proportional to the strength of the UV optical electric field. We also obtained a relative intensity noise of -130dB/Hz at frequencies of 2 to 10 MHz for 266-nm laser light.

  16. 2009年沈阳地区266例手足口病的临床分析%Clinical analysis of 266 cases with hand foot and mouth disease in Shenyang area 2009

    Institute of Scientific and Technical Information of China (English)

    吴丹

    2011-01-01

    Objective To summarize the prevention and treatment of hand food and mouth disease (HFMD),especially the severe cases.Methods We analyzed the data including gender,age,time of onset,place of residence,contact history,clinical manifestation,accessory examinations and clinical outcome of 266 HFMD cases hospitalized in our department from Apr to Oct 2009,and identified the clinical and epidemiologic features associated with HFMD.Results Age group ranged from 4 months to 11 years with 87.6%(233/266) of the cases≤5 years.Most cases were resident in rural or suburban area,the number of which was 3 times as much as urban.Neurological complications were more common,especially in the cases with increases of white blood cell and neutrophil number in peripheral blood.There were 40 cases with etiological examination results.Twelve cases were infected with enterovirus 71 ( EV71 ) and the others were infected with Coxsackievirus A16.Twelve cases with EV71 infection were complicated with meningoencephalitis,encephalitis,encephalomyelitis,one of whom was brain stem encephalitis.Conclusion The high-risk group of HFMD are the children less than 5 years.The suburban and rural are the key areas of prevention and control.The neurological complications are common,especially in the case with EV71 infection and significant increases of white blood cell and neutrophil number in peripheral blood.%目的 总结儿童手足口病,尤其是重症病例的防治经验.方法 采用回顾性分析方法,对2009年4月至10月我院收治的266例手足口病患儿的性别、年龄、发病时间、居住地、接触史、临床表现、辅助检查结果和临床转归等进行综合分析.结果 患儿年龄4个月~11岁,1~5岁患儿占该病发病人数的87.6% (233/266);城郊及农村病例多于市区,二者比例为3∶1;神经系统并发症主要以脑膜脑炎、脑炎、脑脊髓炎为主,该类患儿可伴有外周血白细胞、中性粒细胞的增高.40

  17. High-power, high-repetition-rate performance characteristics of β-BaB₂O₄ for single-pass picosecond ultraviolet generation at 266 nm.

    Science.gov (United States)

    Kumar, S Chaitanya; Casals, J Canals; Wei, Junxiong; Ebrahim-Zadeh, M

    2015-10-19

    We report a systematic study on the performance characteristics of a high-power, high-repetition-rate, picosecond ultraviolet (UV) source at 266 nm based on β-BaB2O4 (BBO). The source, based on single-pass fourth harmonic generation (FHG) of a compact Yb-fiber laser in a two-crystal spatial walk-off compensation scheme, generates up to 2.9 W of average power at 266 nm at a pulse repetition rate of ~80 MHz with a single-pass FHG efficiency of 35% from the green to UV. Detrimental issues such as thermal effects have been studied and confirmed by performing relevant measurements. Angular and temperature acceptance bandwidths in BBO for FHG to 266 nm are experimentally determined, indicating that the effective interaction length is limited by spatial walk-off and thermal gradients under high-power operation. The origin of dynamic color center formation due to two-photon absorption in BBO is investigated by measurements of intensity-dependent transmission at 266 nm. Using a suitable theoretical model, two-photon absorption coefficients as well as the color center densities have been estimated at different temperatures. The measurements show that the two-photon absorption coefficient in BBO at 266 nm is ~3.5 times lower at 200°C compared to that at room temperature. The long-term power stability as well as beam pointing stability is analyzed at different output power levels and focusing conditions. Using cylindrical optics, we have circularized the generated elliptic UV beam to a circularity of >90%. To our knowledge, this is the first time such high average powers and temperature-dependent two-photon absorption measurements at 266 nm are reported at repetition rates as high as ~80 MHz.

  18. Diaquabis(ethylenediamine-κ2N,N′copper(II bis(4-phenylbenzoate 2.66-hydrate

    Directory of Open Access Journals (Sweden)

    José A. Fernandes

    2010-06-01

    Full Text Available In the title complex, [Cu(C2H8N22(H2O2](C13H9O22·2.66H2O, the CuII centre (located at an inversion centre is coordinated by two bidentate ethylenediamine (en ligands and two water O atoms in a typical Jahn–Teller distorted octahedral geometry. The amino groups and the water molecules are disordered over two distinct crystallographic positions with occupancies of 1/3 and 2/3. In the crystal, the cations and anions are disposed in alternating layers. One of the water molecules of crystallization is disordered and the other has a fractional occupation. In the 2/3 occupancy component, water molecules are organized into a chain composed of hexameric units interconnected by carboxylate bridges.

  19. Types and risk factors of cardiac arrhythmias and its effects on pregnancies in 266 hospitalized pregnancy women%266例妊娠患者合并心律失常的类型、危险因素及对妊娠的影响

    Institute of Scientific and Technical Information of China (English)

    李红; 杜静; 薛倩; 刘元生

    2015-01-01

    Objective To investigate the types and risk factors of cardiac arrhythmias and its influence during pregnancy. Methods A total of 266 cases of pregnancies complicated with arrhythmias admitted and delivered were reviewed from June 1993 to June 2012 in Peking University People's Hospital. Results The most common cardiac arrhythmias during pregnancy was sinus tachycardia ( 41. 4% ) (110 / 266). In all kinds of arrhythmia, gestational hypertension was the most common cause of arrhythmia. Single factor analysis showed that, among all the risk factors and the influence on outcomes during pregnancy complicated with arrhythmias, 74. 8% ( 199 / 266 ) of cases were normal cardiac structure, and 25. 2%(67 / 266) of cases were abnormal cardiac structure. There was no significant difference in maternal mortality between pregnancy with or without abnormal cardiac structure(P ﹥ 0. 05). In addition, 86. 5% (230 / 266) of cases were in NYHA grading Ⅰ-Ⅱ, 13. 5% (36 / 266) were in NYHA grading Ⅲ-Ⅳ. The difference of maternal mortality between pregnancy in NYHA grading Ⅲ-Ⅳ and grading Ⅰ-Ⅱ has significance ( P ﹤0. 01) . Conclusions The most common cardiac arrhythmias during pregnancy is sinus tachycardia. Gestational hypertension is the most common cause of arrhythmia. Pregnancy in NYHA grading Ⅲ-Ⅳ has an obvious bad effect on maternal mortality.%目的:分析妊娠合并心律失常的类型、危险因素及对妊娠的影响。方法入选北京大学人民医院1993年6月至2012年6月间妊娠合并心律失常的266例住院分娩患者的临床病历资料,回顾性分析心律失常的危险因素及其对妊娠的影响。结果妊娠合并心律失常中以窦性心动过速最常见,占41.4%(110/266),其次为室性期前收缩和预激综合征合并的室上性心动过速,分别占18.0%(48/266)和8.3%(22/266)。在各种危险因素中,妊娠期高血压综合征最为常见。所有患者中25.2%(67/266)合并器质性心脏病,74.8

  20. Single shot laser multiphoton ionization detection of UF/sub 5/ following the 266 nm photodissociation of UF/sub 6/

    Energy Technology Data Exchange (ETDEWEB)

    Chou, J.S.; Sumida, D.; Stuke, M.; Wittig, C.

    1982-10-01

    By using laser multiphoton ionization and time-of-flight mass filter, nascent uranium pentafluoride has been detected from the 266 nm laser photodissociation of uranium hexafluoride, following a single laser firing. The method can be used to monitor these species under conditions wherein isotopically selective excitation is responsible for the dissociation of uranium hexafluoride. 10 references, 2 figures.

  1. Whole-Genome Sequence of Multidrug-Resistant Campylobacter coli Strain COL B1-266, Isolated from the Colombian Poultry Chain.

    Science.gov (United States)

    Bernal, Johan F; Donado-Godoy, Pilar; Arévalo, Alejandra; Duarte, Carolina; Realpe, María E; Díaz, Paula L; Gómez, Yolanda; Rodríguez, Fernando; Agarwala, Richa; Landsman, David; Mariño-Ramírez, Leonardo

    2016-03-17

    Campylobacter coli is considered one of the main causes of food-borne illness worldwide. We report here the whole-genome sequence of multidrug-resistant Campylobacter coli strain COL B1-266, isolated from the Colombian poultry chain. The genome sequences encode genes for a variety of antimicrobial resistance genes, including aminoglycosides, β-lactams, lincosamides, fluoroquinolones, and tetracyclines.

  2. Study of acoustic fingerprinting of nitromethane and some triazole derivatives using UV 266 nm pulsed photoacoustic pyrolysis technique

    Science.gov (United States)

    Rao, K. S.; Chaudhary, A. K.; Yehya, F.; Kumar, A. Sudheer

    2015-08-01

    We report a comparative study of acoustic fingerprints of nitromethane, nitrobenzene and some nitro rich triazole derivatives using pulsed photoacoustic technique. UV 266 nm wavelength i.e. Fourth harmonic of Q-switched Nd: YAG laser having pulse duration 7 ns and 10 Hz repetition rate is employed to record the time resolved PA spectrum. The PA fingerprint is produced due to absorption of incident UV light by molecule itself and photo dissociation of nitromethane and nitrobenzene at room temperature while in case of triazole it is attributed to the combination of thermal and photo-dissociation process. The entire dissociation process follows the root of cleavage of C-NO2 bond to produce free NO, NO2 and other by product gases due to π∗ ← n excitation. In addition, we have studied the thermal stability criteria of nitro rich triazoles based on the quality factor of acoustic resonance frequencies of the PA cavity. We have also studied the effect of data acquisition time to ascertain the decay behavior of HEMs samples.

  3. Moved by words: Affective ratings for a set of 2,266 Spanish words in five discrete emotion categories.

    Science.gov (United States)

    Ferré, Pilar; Guasch, Marc; Martínez-García, Natalia; Fraga, Isabel; Hinojosa, José Antonio

    2016-07-06

    The two main theoretical accounts of the human affective space are the dimensional perspective and the discrete-emotion approach. In recent years, several affective norms have been developed from a dimensional perspective, including ratings for valence and arousal. In contrast, the number of published datasets relying on the discrete-emotion approach is much lower. There is a need to fill this gap, considering that discrete emotions have an effect on word processing above and beyond those of valence and arousal. In the present study, we present ratings from 1,380 participants for a set of 2,266 Spanish words in five discrete emotion categories: happiness, anger, fear, disgust, and sadness. This will be the largest dataset published to date containing ratings for discrete emotions. We also present, for the first time, a fine-grained analysis of the distribution of words into the five emotion categories. This analysis reveals that happiness words are the most consistently related to a single, discrete emotion category. In contrast, there is a tendency for many negative words to belong to more than one discrete emotion. The only exception is disgust words, which overlap least with the other negative emotions. Normative valence and arousal data already exist for all of the words included in this corpus. Thus, the present database will allow researchers to design studies to contrast the predictions of the two most influential theoretical perspectives in this field. These studies will undoubtedly contribute to a deeper understanding of the effects of emotion on word processing.

  4. Investigation on the attitude of 1 266 women to menstrual cycle%1266例妇女对月经周期的态度调查

    Institute of Scientific and Technical Information of China (English)

    闵丽华; 吕群; 张潇潇; 张小建; 周远利; 漆平; 吴芳玉

    2011-01-01

    Objective: To survey the optimal menstrual cycle of the women. Methods:A self - designed questionnaire was used to investigate the attitude of 1 266 women who were treated in department of gynecology in the hospital to menstrual cycle. Results; Among 1 266 women, 70. 46% of the women considered that the optimal menstrual cycle was once a month; 61. 69% of the women was unwilling to change the menstrual cycle because they thought the menstrual cycle of once a month was a natural cycle; 59. 48% of the women wanted to change the menstrual cycle because of the discomfort induced by menstruation. Conclusion: The women investigated generally prefer monthly menstruation and they don't want to change this regulation, the great majority of the women think that menstruation is a natural menstrual cycle rhythm.%目的:调查受试者理想的月经周期.方法:采用自设问卷,对1 266例在四川省人民医院妇科门诊就诊的有月经妇女进行月经认识态度调查.结果:1 266例妇女中,70.46%的妇女希望的月经周期为每月1次;其中61.69%的妇女不想改变月经周期的原因是认为每月1次是一种自然周期;59.48%的妇女想改变月经周期的原因是月经会带来不适.结论:被调查妇女普遍偏爱一月一次的月经周期并不愿改变这种规律,多数人认为月经是一种自然周期节律.

  5. Non-Thermal X-ray Emission from the Northwestern Rim of the Galactic Supernova Remnant G266.2-1.2 (RX J0852.0-4622)

    CERN Document Server

    Pannuti, Thomas G; Filipovic, Miroslav D; De Horta, Ain; Stupar, Milorad; Agrawal, Rashika

    2010-01-01

    We present a detailed spatially-resolved spectroscopic analysis of two X-ray observations (with a total integration time of 73280 seconds) made of the luminous northwestern rim complex of the Galactic supernova remnant (SNR) G266.2-1.2 (RX J0852.0-4622) with the Chandra X-ray Observatory. G266.2-1.2 is a member of a class of Galactic SNRs which feature X-ray spectra dominated by non-thermal emission: in the cases of these SNRs, the emission is believed to have a synchrotron origin and studies of the X-ray spectra of these SNRs can lend insights into how SNRs accelerate cosmic-ray particles. The Chandra observations have clearly revealed fine structure in this rim complex and the spectra of these features are dominated by non-thermal emission. We have measured the length scales of the upstream structures at eight positions along the rim and derive lengths of 0.02-0.08 pc (assuming a distance of 750 pc to G266.2-1.2). We have also extracted spectra from seven regions in the rim complex and fit these spectra wit...

  6. In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells.

    Directory of Open Access Journals (Sweden)

    Paolo Arosio

    Full Text Available Excessive production of monoclonal light chains due to multiple myeloma can induce aggregation-related disorders, such as light chain amyloidosis (AL and light chain deposition diseases (LCDD. In this work, we produce a non-amyloidogenic IgE λ light chain dimer from human mammalian cells U266, which originated from a patient suffering from multiple myeloma, and we investigate the effect of several physicochemical parameters on the in vitro stability of this protein. The dimer is stable in physiological conditions and aggregation is observed only when strong denaturating conditions are applied (acidic pH with salt at large concentration or heating at melting temperature T(m at pH 7.4. The produced aggregates are spherical, amorphous oligomers. Despite the larger β-sheet content of such oligomers with respect to the native state, they do not bind Congo Red or ThT. The impossibility to obtain fibrils from the light chain dimer suggests that the occurrence of amyloidosis in patients requires the presence of the light chain fragment in the monomer form, while dimer can form only amorphous oligomers or amorphous deposits. No aggregation is observed after denaturant addition at pH 7.4 or at pH 2.0 with low salt concentration, indicating that not a generic unfolding but specific conformational changes are necessary to trigger aggregation. A specific anion effect in increasing the aggregation rate at pH 2.0 is observed according to the following order: SO(4(-≫Cl(->H(2PO(4(-, confirming the peculiar role of sulfate in promoting protein aggregation. It is found that, at least for the investigated case, the mechanism of the sulfate effect is related to protein secondary structure changes induced by anion binding.

  7. In vitro aggregation behavior of a non-amyloidogenic λ light chain dimer deriving from U266 multiple myeloma cells.

    Science.gov (United States)

    Arosio, Paolo; Owczarz, Marta; Müller-Späth, Thomas; Rognoni, Paola; Beeg, Marten; Wu, Hua; Salmona, Mario; Morbidelli, Massimo

    2012-01-01

    Excessive production of monoclonal light chains due to multiple myeloma can induce aggregation-related disorders, such as light chain amyloidosis (AL) and light chain deposition diseases (LCDD). In this work, we produce a non-amyloidogenic IgE λ light chain dimer from human mammalian cells U266, which originated from a patient suffering from multiple myeloma, and we investigate the effect of several physicochemical parameters on the in vitro stability of this protein. The dimer is stable in physiological conditions and aggregation is observed only when strong denaturating conditions are applied (acidic pH with salt at large concentration or heating at melting temperature T(m) at pH 7.4). The produced aggregates are spherical, amorphous oligomers. Despite the larger β-sheet content of such oligomers with respect to the native state, they do not bind Congo Red or ThT. The impossibility to obtain fibrils from the light chain dimer suggests that the occurrence of amyloidosis in patients requires the presence of the light chain fragment in the monomer form, while dimer can form only amorphous oligomers or amorphous deposits. No aggregation is observed after denaturant addition at pH 7.4 or at pH 2.0 with low salt concentration, indicating that not a generic unfolding but specific conformational changes are necessary to trigger aggregation. A specific anion effect in increasing the aggregation rate at pH 2.0 is observed according to the following order: SO(4)(-)≫Cl(-)>H(2)PO(4)(-), confirming the peculiar role of sulfate in promoting protein aggregation. It is found that, at least for the investigated case, the mechanism of the sulfate effect is related to protein secondary structure changes induced by anion binding.

  8. Chemical, optical and other data collected aboard the THOMAS G. THOMPSON during cruise TN266 in the Coastal Waters of SE Alaska and North Pacific Ocean from 2011-06-27 to 2011-07-27 (NODC Accession 0104365)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0104365 includes chemical, optical and other data collected aboard the THOMAS G. THOMPSON during cruise TN266 in the Coastal Waters of SE Alaska and...

  9. Effect of Buffer Layer on Epitaxial Growth of YSZ Deposited on Si Substrate by Slower Q-switched 266 nm YAG Laser

    Science.gov (United States)

    Kaneko, Satoru; Akiyama, Kensuke; Shimizu, Yoshitada; Ito, Takeshi; Yasaka, Shinji; Mitsuhashi, Masahiko; Ohya, Seishiro; Saito, Keisuke; Watanabe, Takayuki; Okamoto, Shoji; Funakubo, Hiroshi

    2004-04-01

    Yttria-stabilized zirconia (YSZ) was grown on Si(100) substrate by pulsed laser deposition (PLD). The laser used in this study was a 266 nm YAG laser with a second function generator modulating only the Q-switch while the primary generator modulated the flash lamp (slower Q-switch). Epitaxial growth was verified on YSZ film deposited without oxygen gas followed by primary deposition in oxygen atmosphere on Si substrate with a ˜0.4-nm-thin oxide layer. The crystallinity was strongly dependent on the thickness of the buffer layer deposited prior to the primary deposition of YSZ. The epitaxial growth was confirmed by φ scan, and ω scan (rocking curve) showed the full width at half maximum (FWHM) of 1.1 deg. The required oxygen pressure for epitaxial growth was quite high compared to that of excimer deposition.

  10. Non-thermal X-ray Emission from the Northwestern Rim of the Galactic Supernova Remnant G266.2-1.2 (RX J0852.0-4622)

    Science.gov (United States)

    Pannuti, Thomas G.; Allen, Glenn E.; Filipović, Miroslav D.; De Horta, Ain; Stupar, Milorad; Agrawal, Rashika

    2010-10-01

    We present a detailed spatially resolved spectroscopic analysis of two observations (with a total integration time of 73280 s) made of the X-ray-luminous northwestern rim complex of the Galactic supernova remnant (SNR) G266.2-1.2 (RX J0852.0-4622) with the Chandra X-ray Observatory. G266.2-1.2 is a member of a class of Galactic SNRs which feature X-ray spectra dominated by non-thermal emission: in the cases of these SNRs, the emission is believed to have a synchrotron origin and studies of the X-ray spectra of these SNRs can lend insight into how SNRs accelerate cosmic-ray particles. The Chandra observations have clearly revealed fine structure in this rim complex (including a remarkably well-defined leading shock) and the spectra of these features are dominated by non-thermal emission. We have measured the length scales of the upstream structures at eight positions along the rim and derive lengths of 0.02-0.08 pc (assuming a distance of 750 pc to G266.2-1.2). We have also extracted spectra from seven regions in the rim complex (as sampled by the ACIS-S2, -S3, and -S4 chips) and fit these spectra with such models as a simple power law as well as the synchrotron models SRCUT and SRESC. We have constrained our fits to the latter two models using estimates for the flux densities of these filaments at 1 GHz as determined from radio observations of this rim complex made with the Australia Telescope Compact Array. Statistically acceptable fits to all seven regions are derived using each model: differences in the fit parameters (such as photon index and cutoff frequency) are seen in different regions, which may indicate variations in shock conditions and the maximum energies of the cosmic-ray electrons accelerated at each region. Finally, we estimate the maximum energy of cosmic-ray electrons accelerated along this rim complex to be approximately 40 TeV (corresponding to one of the regions of the leading shock structure assuming a magnetic field strength of 10 μG). We

  11. Photodissociation of acetone from 266 to 312 nm: Dynamics of CH3 + CH3CO channels on the S0 and T1 states

    Science.gov (United States)

    Lee, Kin Long Kelvin; Nauta, Klaas; Kable, Scott H.

    2017-01-01

    The photodissociation dynamics of acetone (CH3)2CO, cooled in a molecular beam, have been explored over the wavelength range 266-312 nm. Nascent CH3 fragments were detected by resonance-enhanced multiphoton ionization, followed by mass-selected ion imaging. For photolysis at λ = 306 nm, the image shows a sharp ring, which, when converted to a translational energy distribution, reveals a narrow Gaussian peak with a maximum at 90% of the available energy. As the photolysis energy is increased, the distribution slowly broadens and shifts to higher recoil translational energy. The fraction of available energy in translation energy decreases in favour of internal energy of the CH3CO fragment. These observations are consistent with a dynamical model in which the energy of the exit channel barrier on the T1 surface evolves mostly into relative translational energy. Energy in excess of the barrier is partitioned statistically into all degrees of freedom. No evidence was found for any other dynamical pathway producing CH3 fragments, including reaction on S0 or S1, for dissociation between 306 and 266 nm. For λ > 306 nm, a diffuse, slow recoil component to the image appears. The translational energy distribution for this component is fit well by a statistical prior distribution of energy. We attribute this component to dissociation on the S0, ground state surface; to our knowledge, this is the first direct observation of this channel. The appearance of S0 dynamics and the disappearance of the T1 component are consistent with previously inferred barrier height on T1 for the production of CH3CO + CH3. The possible atmospheric implications of our findings are discussed.

  12. A non-plume model for the Permian protracted (266-286 Ma) basaltic magmatism in the Beishan-Tianshan region, Xinjiang, Western China

    Science.gov (United States)

    Xue, Sheng-Chao; Li, Chusi; Qin, Ke-Zhang; Tang, Dong-Mei

    2016-07-01

    The convenient mantle plume model for the Permian protracted mafic-ultramafic intrusions and mafic dykes (266-286 Ma) in the Beishan-Tianshan region, northern Xinjiang, western China can be rejected, because their temporal-spatial distribution does not show a hotspot track predicted by such model. New zircon U-Pb ages reveal that two small mafic dyke clusters (Podong, 280.5 ± 2 Ma; Luodong, 266.2 ± 3.2 Ma) that are separated by only ~ 20 km in the Pobei area, the southernmost part of the Beishan-Tianshan region, have a large age difference of ~ 18 Ma. The older mafic dykes are characterized by nearly flat mantle-normalized rare-earth-element patterns, pronounced negative Nb-Ta anomalies and positive εNd(t) values from 5.5 to 7.5, similar to the majority of the Permian mafic-ultramafic intrusions in the region. The younger mafic dykes are characterized by significant light rare-earth-element enrichments as well as pronounced negative Nb-Ta anomalies, plus lower εNd(t) (- 1.2 to 2.6) values and higher initial 87Sr/86Sr ratios than the older mafic dykes. The observed compositional variations can be explained by source mantle heterogeneity plus different degrees of crustal contamination. Overall, the Permian mafic-ultramafic rocks in the Beishan-Tianshan region are geochemically consistent with the products of basaltic magmatism induced by lithospheric delamination and asthenosphere upwelling in a convergent tectonic zone.

  13. Planck early results. XXVI. Detection with Planck and confirmation by XMM-Newton of PLCK G266.6-27.3, an exceptionally X-ray luminous and massive galaxy cluster at z ~ 1

    DEFF Research Database (Denmark)

    Delabrouille, J.; Le Jeune, M.; Patanchon, G.;

    2011-01-01

    We present first results on PLCKG266.6-27.3, a galaxy cluster candidate detected at a signal-to-noise ratio of 5 in the Planck All Sky survey. An XMM-Newton validation observation has allowed us to confirm that the candidate isa bona fide galaxy cluster. With these X-ray data we measure an accura...

  14. ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial

    Directory of Open Access Journals (Sweden)

    Pownall Henry J

    2011-06-01

    Full Text Available Abstract Background Elevated triglyceride levels are a risk factor for cardiovascular disease. Angiopoietin-like protein 4 (Angptl4 is a metabolic factor that raises plasma triglyceride levels by inhibiting lipoprotein lipase (LPL. In non-diabetic individuals, the ANGPTL4 coding variant E40K has been associated with lower plasma triglyceride levels while the T266M variant has been associated with more modest effects on triglyceride metabolism. The objective of this study was to determine whether ANGPTL4 E40K and T266M are associated with triglyceride levels in the setting of obesity and T2D, and whether modification of triglyceride levels by these genetic variants is altered by a lifestyle intervention designed to treat T2D. Methods The association of ANGPTL4 E40K and T266M with fasting triglyceride levels was investigated in 2,601 participants from the Look AHEAD Clinical Trial, all of whom had T2D and were at least overweight. Further, we tested for an interaction between genotype and treatment effects on triglyceride levels. Results Among non-Hispanic White Look AHEAD participants, ANGPTL4 K40 carriers had mean triglyceride levels of 1.61 ± 0.62 mmol/L, 0.33 mmol/L lower than E40 homozygotes (p = 0.001. Individuals homozygous for the minor M266 allele (MAF 30% had triglyceride levels of 1.75 ± 0.58 mmol/L, 0.24 mmol/L lower than T266 homozygotes (p = 0.002. The association of the M266 with triglycerides remained significant even after removing K40 carriers from the analysis (p = 0.002. There was no interaction between the weight loss intervention and genotype on triglyceride levels. Conclusions This is the first study to demonstrate that the ANGPTL4 E40K and T266M variants are associated with lower triglyceride levels in the setting of T2D. In addition, our findings demonstrate that ANGPTL4 genotype status does not alter triglyceride response to a lifestyle intervention in the Look AHEAD study.

  15. Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.

    Directory of Open Access Journals (Sweden)

    I-Ting Chow

    Full Text Available Susceptibility to type 1 diabetes (T1D is strongly associated with MHC class II molecules, particularly HLA-DQ8 (DQ8: DQA1*03:01/DQB1*03:02. Monitoring T1D-specific T cell responses to DQ8-restricted epitopes may be key to understanding the immunopathology of the disease. In this study, we examined DQ8-restricted T cell responses to glutamic acid decarboxylase 65 (GAD65 using DQ8 tetramers. We demonstrated that GAD65 121-140 and GAD65 250-266 elicited responses from DQ8+ subjects. Circulating CD4+ T cells specific for these epitopes were detected significantly more often in T1D patients than in healthy individuals after in vitro expansion. T cell clones specific for GAD65 121-140 and GAD65 250-266 carried a Th1-dominant phenotype, with some of the GAD65 121-140-specific T cell clones producing IL-17. GAD65 250-266-specific CD4+ T cells could also be detected by direct ex vivo staining. Analysis of unmanipulated peripheral blood mononuclear cells (PBMCs revealed that GAD65 250-266-specific T cells could be found in both healthy and diabetic individuals but the frequencies of specific T cells were higher in subjects with type 1 diabetes. Taken together, our results suggest a proinflammatory role for T cells specific for DQ8-restricted GAD65 121-140 and GAD65 250-266 epitopes and implicate their possible contribution to the progression of T1D.

  16. Ca48+Bk249 Fusion Reaction Leading to Element Z =117: Long-Lived α-Decaying Db270 and Discovery of Lr266

    Science.gov (United States)

    Khuyagbaatar, J.; Yakushev, A.; Düllmann, Ch. E.; Ackermann, D.; Andersson, L.-L.; Asai, M.; Block, M.; Boll, R. A.; Brand, H.; Cox, D. M.; Dasgupta, M.; Derkx, X.; Di Nitto, A.; Eberhardt, K.; Even, J.; Evers, M.; Fahlander, C.; Forsberg, U.; Gates, J. M.; Gharibyan, N.; Golubev, P.; Gregorich, K. E.; Hamilton, J. H.; Hartmann, W.; Herzberg, R.-D.; Heßberger, F. P.; Hinde, D. J.; Hoffmann, J.; Hollinger, R.; Hübner, A.; Jäger, E.; Kindler, B.; Kratz, J. V.; Krier, J.; Kurz, N.; Laatiaoui, M.; Lahiri, S.; Lang, R.; Lommel, B.; Maiti, M.; Miernik, K.; Minami, S.; Mistry, A.; Mokry, C.; Nitsche, H.; Omtvedt, J. P.; Pang, G. K.; Papadakis, P.; Renisch, D.; Roberto, J.; Rudolph, D.; Runke, J.; Rykaczewski, K. P.; Sarmiento, L. G.; Schädel, M.; Schausten, B.; Semchenkov, A.; Shaughnessy, D. A.; Steinegger, P.; Steiner, J.; Tereshatov, E. E.; Thörle-Pospiech, P.; Tinschert, K.; Torres De Heidenreich, T.; Trautmann, N.; Türler, A.; Uusitalo, J.; Ward, D. E.; Wegrzecki, M.; Wiehl, N.; Van Cleve, S. M.; Yakusheva, V.

    2014-05-01

    The superheavy element with atomic number Z =117 was produced as an evaporation residue in the Ca48+Bk249 fusion reaction at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. The radioactive decay of evaporation residues and their α-decay products was studied using a detection setup that allowed measuring decays of single atomic nuclei with half-lives between sub-μs and a few days. Two decay chains comprising seven α decays and a spontaneous fission each were identified and are assigned to the isotope 117294 and its decay products. A hitherto unknown α-decay branch in Db270 (Z =105) was observed, which populated the new isotope Lr266 (Z =103). The identification of the long-lived (T1/2=1.0-0.4+1.9 h) α-emitter Db270 marks an important step towards the observation of even more long-lived nuclei of superheavy elements located on an "island of stability."

  17. 48Ca+249Bk fusion reaction leading to element Z = 117: long-lived α-decaying 270Db and discovery of 266Lr.

    Science.gov (United States)

    Khuyagbaatar, J; Yakushev, A; Düllmann, Ch E; Ackermann, D; Andersson, L-L; Asai, M; Block, M; Boll, R A; Brand, H; Cox, D M; Dasgupta, M; Derkx, X; Di Nitto, A; Eberhardt, K; Even, J; Evers, M; Fahlander, C; Forsberg, U; Gates, J M; Gharibyan, N; Golubev, P; Gregorich, K E; Hamilton, J H; Hartmann, W; Herzberg, R-D; Heßberger, F P; Hinde, D J; Hoffmann, J; Hollinger, R; Hübner, A; Jäger, E; Kindler, B; Kratz, J V; Krier, J; Kurz, N; Laatiaoui, M; Lahiri, S; Lang, R; Lommel, B; Maiti, M; Miernik, K; Minami, S; Mistry, A; Mokry, C; Nitsche, H; Omtvedt, J P; Pang, G K; Papadakis, P; Renisch, D; Roberto, J; Rudolph, D; Runke, J; Rykaczewski, K P; Sarmiento, L G; Schädel, M; Schausten, B; Semchenkov, A; Shaughnessy, D A; Steinegger, P; Steiner, J; Tereshatov, E E; Thörle-Pospiech, P; Tinschert, K; Torres De Heidenreich, T; Trautmann, N; Türler, A; Uusitalo, J; Ward, D E; Wegrzecki, M; Wiehl, N; Van Cleve, S M; Yakusheva, V

    2014-05-02

    The superheavy element with atomic number Z=117 was produced as an evaporation residue in the (48)Ca+(249)Bk fusion reaction at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. The radioactive decay of evaporation residues and their α-decay products was studied using a detection setup that allowed measuring decays of single atomic nuclei with half-lives between sub-μs and a few days. Two decay chains comprising seven α decays and a spontaneous fission each were identified and are assigned to the isotope (294)117 and its decay products. A hitherto unknown α-decay branch in (270)Db (Z = 105) was observed, which populated the new isotope (266)Lr (Z = 103). The identification of the long-lived (T(1/2) = 1.0(-0.4)(+1.9) h) α-emitter (270)Db marks an important step towards the observation of even more long-lived nuclei of superheavy elements located on an "island of stability."

  18. Hydroxyl radical consumption following photolysis of vapor-phase hydrogen peroxide at 266 nm: Implications for photofragmentation laser-induced fluorescence measurements of hydrogen peroxide

    Science.gov (United States)

    Johansson, O.; Bood, J.; Aldén, M.; Lindblad, U.

    2009-10-01

    The decay of OH concentration following photolysis of room-temperature vapor-phase hydrogen peroxide is studied as a function of photolysis fluence at 266 nm in an open air environment. The rate of decay is found to increase with increasing photolysis fluence, i.e., with increasing number of photodissociated H2O2(g) molecules. Single-exponential functions approximate the OH concentration decay rather well, even for higher photolysis levels, and the decay time is shown to be inversely proportional to the H2O2(g) concentration. For fluences of about 450 mJ/cm2 the difference between a single-exponential decay and measured data is becoming evident after approximately 150 μs. Calculations based on a chemical kinetics model agree well with experimental data also for times >150 μs. By combining the model with measurements, the actual photolysis levels used in experiments are estimated. The best fit between measured data and the model suggests that about 1.1% of the H2O2(g) molecules are dissociated with a photolysis fluence of ˜450 mJ/cm2, in reasonable agreement with a Beer-Lambert based estimation. Excitation scans did not unfold any differences between OH spectra recorded at different photolysis fluences.

  19. Planck early results. XXVI. Detection with Planck and confirmation by XMM-Newton of PLCK G266.6-27.3, an exceptionally X-ray luminous and massive galaxy cluster at z ~ 1

    DEFF Research Database (Denmark)

    Delabrouille, J.; Le Jeune, M.; Patanchon, G.;

    2011-01-01

    We present first results on PLCKG266.6-27.3, a galaxy cluster candidate detected at a signal-to-noise ratio of 5 in the Planck All Sky survey. An XMM-Newton validation observation has allowed us to confirm that the candidate isa bona fide galaxy cluster. With these X-ray data we measure an accurate...... redshift, z = 0.94 ± 0.02, and estimate the cluster mass to be M 500 = (7.8 ± 0.8) × 1014 M. PLCKG266.6-27.3 is an exceptional system: its luminosity of LX [0.5-2.0 keV] = (1.4 ± 0.05) × 1045 erg s-1 equals that of the two most luminous known clusters in the z > 0.5 universe, and it is one of the most...... massive clusters at z ~ 1. Moreover, unlike the majority of high-redshift clusters, PLCKG266.6-27.3 appears to be highly relaxed. This observation confirms Planck's capability of detecting high-redshift, high-mass clusters, and opens the way to the systematic study of population evolution...

  20. Planck Early Results XXVI: Detection with Planck and confirmation by XMM-Newton of PLCK G266.6-27.3, an exceptionally X-ray luminous and massive galaxy cluster at z~1

    CERN Document Server

    Aghanim, N; Atrio-Barandela, F; Aumont, J; Baccigalupi, C; Balbi, A; Banday, A J; Bartlett, J G; Battaner, E; Benabed, K; Bernard, J -P; Bersanelli, M; Bhatia, R; Böhringer, H; Bonaldi, A; Bond, J R; Borgani, S; Borrill, J; Bouchet, F R; Brown, M L; Burigana, C; Cabella, P; Carvalho, P; Chiang, L -Y; Chiang, C; Chon, G; Churazov, E; Colafrancesco, S; Colombi, S; Crill, B P; Cuttaia, F; Da Silva, A; Dahle, H; Danese, L; D'Arcangelo, O; Davis, R J; de Bernardis, P; de Gasperis, G; de Zotti, G; Delabrouille, J; Delouis, J -M; Démoclès, J; Désert, F -X; Dickinson, C; Diego, J M; Dole, H; Donzelli, S; Doré, O; Douspis, M; Dupac, X; Efstathiou, G; En\\sslin, T A; Eriksen, H K; Finelli, F; Flores-Cacho, I; Forni, O; Fosalba, P; Fromenteau, S; Ganga, K; Génova-Santos, R T; Giard, M; González-Nuevo, J; González-Riestra, R; Górski, K M; Gregorio, A; Harrison, D; Heinämäki, P; Hernández-Monteagudo, C; Hildebrandt, S R; Hivon, E; Hurier, G; Jones, W C; Juvela, M; Keskitalo, R; Kneissl, R; Kurki-Suonio, H; Lamarre, J -M; Lasenby, A; Jeune, M Le; Leach, S; Leonardi, R; Leroy, C; Liddle, A; Lilje, P B; López-Caniego, M; Luzzi, G; Macías-Pérez, J F; Maino, D; Marleau, F; Martínez-González, E; Masi, S; Matarrese, S; Mazzotta, P; Meinhold, P R; Melchiorri, A; Melin, J -B; Mendes, L; Mennella, A; Miville-Deschênes, M -A; Moneti, A; Montier, L; Morgante, G; Munshi, D; Naselsky, P; Natoli, P; Nevalainen, J; Norgaard-Nielsen, H U; Noviello, F; O'Dwyer, I J; Paladini, R; Pasian, F; Patanchon, G; Pearson, T J; Perdereau, O; Piacentini, F; Pierpaoli, E; Piffaretti, R; Pointecouteau, E; Polenta, G; Ponthieu, N; Popa, L; Pratt, G W; Prézeau, G; Prunet, S; Rachen, J P; Rebolo, R; Reinecke, M; Ricciardi, S; Riller, T; Rubiño-Martín, J A; Saar, E; Savini, G; Scott, D; Smoot, G F; Sutton, D; Sygnet, J -F; Tauber, J A; Terenzi, L; Toffolatti, L; Tristram, M; Türler, M; Valenziano, L; Vielva, P; Villa, F; Vittorio, N; Wade, L A; Wandelt, B D; White, M; Yvon, D; Zacchei, A; Zonca, A

    2011-01-01

    We present first results on PLCK G266.6-27.3, a galaxy cluster candidate detected at a signal-to-noise ratio of 5 in the Planck All Sky survey. An XMM-Newton validation observation has allowed us to confirm that the candidate is a bona fide galaxy cluster. With these X-ray data we measure an accurate redshift, z = 0.94 +/- 0.02, and estimate the cluster mass to be M_500 = (7.8 +/- 0.8)e+14 solar masses. PLCK G266.6-27.3 is an exceptional system: its luminosity of L_X(0.5-2.0 keV)=(1.4 +/- 0.05)e+45 erg/s, equals that of the two most luminous known clusters in the z > 0.5 universe, and it is one of the most massive clusters at z~1. Moreover, unlike the majority of high redshift clusters, PLCK G266.6-27.3 appears to be highly relaxed. This observation confirms Planck's capability to detect high redshift, high mass clusters, and opens the way to the systematic study of population evolution in the exponential tail of the mass function.

  1. China Report, Agriculture, No. 266

    Science.gov (United States)

    2007-11-02

    province had turned over to the state a grand total of over 735,000 tons of sugar . In the 1982-83 extraction season, there was a big increase in cane ... Fertilizer Prices (RENMIN RIBAO, 2 Jun 83).... 9 Beijing Briefs Cotton Growth Chemical 11 Pastureland Development 11 Fuj ian Province Has...Guangdong Hebei Spring Planting Completed After Long Wet Spell (NANFANG RIBAO, 8 May 83) 20 Province Sets Record For Highest Sugar Output (NANFANG

  2. Development of a fiber-optic laser delivery system capable of delivering 213 and 266 nm pulsed Nd:YAG laser radiation for tissue ablation in a fluid environment.

    Science.gov (United States)

    Miller, Joe; Yu, Xiao-Bo; Yu, Paula K; Cringle, Stephen J; Yu, Dao-Yi

    2011-02-20

    Ultraviolet (UV) lasers have the capability to precisely remove tissue via ablation; however, due to strong absorption of the applicable portion the UV spectrum, their surgical use is currently limited to extraocular applications at the air/tissue boundary. Here we report the development and characterization of a fiber-optic laser delivery system capable of outputting high-fluence UV laser pulses to internal tissue surfaces. The system has been developed with a view to intraocular surgical applications and has been demonstrated to ablate ocular tissue at the fluid/tissue boundary. The fifth (213 nm) and fourth(266 nm) harmonics of a Nd:YAG laser were launched into optical fibers using a hollow glass taper to concentrate the beam. Standard and modified silica/silica optical fibers were used, all commercially available. The available energy and fluence as a function of optical fiber length was evaluated and maximized. The maximum fluence available to ablate tissue was affected by the wavelength dependence of the fiber transmission; this maximum fluence was greater for 266 nm pulses (8.4 J/cm2) than for 213 nm pulses (1.4 J/cm2). The type of silica/silica optical fiber used did not affect the transmission efficiency of 266 nm pulses, but transmission of 213 nm pulses was significantly greater through modified silica/silica optical fiber. The optical fiber transmission efficiency of 213 nm pulses decreased as a function of number of pulses transmitted, whereas the transmission efficiency of 266 nm radiation was unchanged. Single pulses have been used to ablate fresh porcine ocular tissue. In summary, we report a method for delivering the fifth (213 nm) and fourth (266 nm) harmonics of a Nd:YAG laser to the surface of immersed tissue, the reliability and stability of the system has been characterized, and proof of concept via tissue ablation of porcine ocular tissue demonstrates the potential for the intraocular surgical application of this

  3. BBO四倍频全固态Nd:YVO4紫外激光器%ALL-SOLID-STATE Nd:YVO4 UV LASER AT 266nm BY FOURTH HARMONIC USING A BBO CRYSTAL

    Institute of Scientific and Technical Information of China (English)

    何京良; 卢兴强; 贾玉磊; 满宝元; 祝世宁; 朱永元

    2000-01-01

    报道了用BBO晶体对激光二极管抽运Nd:YVO4晶体声光调Q产生的1.064μm激光进行四倍频,实现平均功率为63mW准连续波266nm紫外激光运转,重复频率为12.5kHz、单脉冲能量5μJ、峰值功率达252W,绿光-紫外光转换效率达11%.

  4. Microstructure Evolution of Electron Beam Physical Vapour Deposited Ni-23.5Cr-2.66Co-1.44Al Superalloy Sheet During Annealing at 600 °C

    Directory of Open Access Journals (Sweden)

    Li Mingwei

    2013-02-01

    Full Text Available Microstructure evolution of electron beam physical vapour deposited (EB-PVD Ni‑23.5Cr‑2.66Co‑1.44Al superalloy sheet during annealing at 600 °C was investigated. The results showed that the as-deposited alloy was composed of only g phase. After annealing at 600 °C, the locations of diffraction peaks were still the same. The (220 diffraction peak of the deposition side increased with annealing time. The sheet on deposited side had a tendency toward forming (220 texture during post-annealing. No obvious texture was observed at as-deposited and annealed sheet at 600 °C in substrate side. The count and size of "voids" decreased with time. The size of grains increased obviously with annealing time. The ultimate tensile strength of EB-PVD Ni-23.5Cr-2.66Co-1.44Al alloy sheet increased from 641 MPa to 829 MPa after annealing at 600 °C for 30 hours.

  5. 奉贤区13266例围产儿出生缺陷分析%Analysis on 13 266 perinatal infants with birth defects in Fengxian district

    Institute of Scientific and Technical Information of China (English)

    顾维红

    2011-01-01

    目的:了解奉贤区出生缺陷发生情况、分布特征、影响因素,为降低出生缺陷发生制定干预措施提供依据.方法:采用回顾性方法对2008年1月1日~2009年12月31日奉贤区13 266例监测围产儿进行分析.结果:①奉贤区两年间出生缺陷儿188例,出生缺陷率为14.17%;②出生缺陷前5位分别是先天性心脏病、多指(趾)、总唇裂、血管瘤和神经管畸形;③出生缺陷发生在男女性别、户籍、出生时间方面差异无统计学意义,但与孕妇年龄有关(x2=7.517,P<0.05);④出生缺陷儿死亡与非出生缺陷儿死亡差异有统计学意义(x2=1 345.85,P<0.001);⑤产前诊断及治疗性终止妊娠可降低活产婴儿的出生缺陷发生率,并使出生缺陷顺位发生改变.结论:出生缺陷发生与孕妇年龄有关,与性别、受孕时间、户籍无关;出生缺陷儿死亡是围产儿死亡的主要原因;做好三级预防是降低出生缺陷发生,降低围产儿死亡率的重要措施.%Objective: To understand the occurrence, distribution characteristics and effect factors of birth defects in Fengxian distriet, provide a basis for making intervention measures to reduce the occurrence of birth defects. Methods: A retrospective method was adopted to analyze 13 266 perinatal infants in Fengxian district from January 1,2008 to December 31,2009. Results: From 2008 to 2009,188 perinatal infants with birth defects were born in Fengxian district, the incidence of birth defects was 14. 17‰; the first five birth defects were congenital heart disease, polydaetylism, total cleft lip, hemangioma and neural tube defect; there was no significant difference in incidences of birth defects between the perinatal infants with different genders, census registers and times of birth, but the incidences of birth defects were related to maternal age (x2 = 7. 517, P < 0. 05 ); there was significant difference in perinatal mortality between the perinatal infants with birth

  6. Synthesis of 2-Methyl-4- (2,6,6-trimethyl-1-cyclohexen-1-yl) -2-butenal%2-甲基-4-(2,6,6-三甲基-1-环己烯-1-基)-2-丁烯醛的合成

    Institute of Scientific and Technical Information of China (English)

    蒋晓岳; 胡四平; 宋小华; 叶伟东; 沈润溥

    2011-01-01

    2,6,6-Trimethyl-1-cyclohexen-1-aldehyde underwent Wittig-Horner condensation with (3-methoxy-2-methylallyl) phosphonic acid diethyl ester to obtain 1-methoxy-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,3-butadiene, which was subjected to hydrolysis catalyzed by acid to obtain 2-methyl-4- (2,6,6-trimethyl-1-cyclohexen-1-yl)-2-butenal, the key intermediate of vitamin A. The overall yield was about 47 %.%2,6,6-三甲基-1-环己烯-1-甲醛与(3-甲氧基-2-甲基烯丙基)膦酸二乙酯经Wittig-Homer缩合制得1-甲氧基-2-甲基-4-(2,6,6-三甲基-1-环己烯-1-基)-1,3-丁二烯,然后经酸催化水解得到维生素A的关键中间体2-甲基-4-(2,6,6-三甲基-1-环己烯-1-基)-2-丁烯醛,总收率约47%.

  7. 49 CFR 266.17 - Applications.

    Science.gov (United States)

    2010-10-01

    ..., promotion, and development with provision for public participation; and that it is designated and directed... of the results of a title search, and the basis for the proposed acquisition price including...

  8. Reference: 266 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Najjar Mohammad B et al. 2005 Sep. Plant J. 43(6):789-98. The DNA damage response and DNA recombination are two interrelated mechanis...ms involved in maintaining the integrity of the genome, but in plants they are poor

  9. 38 CFR 26.6 - Environmental documents.

    Science.gov (United States)

    2010-07-01

    ... technology; (v) Potential presence of an endangered species, archeological remains, or other protected...) Environmental Impact Statements. The head of each VA element shall include a detailed written statement “in... significantly affecting the quality of the human environmental.” NEPA 102(2), 42 U.S.C. 4332(2) see...

  10. 7 CFR 1822.266 - Limitations.

    Science.gov (United States)

    2010-01-01

    ... PRIMARILY FOR REAL ESTATE PURPOSES RURAL HOUSING LOANS AND GRANTS Rural Housing Site Loan Policies... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... be for housing low- and moderate-income families and may be sold to families, nonprofit...

  11. 40 CFR 266.100 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... be exceeded for any toxic organic compound that may be emitted based on dispersion modeling to... paragraph including limits on levels of toxic organic constituents and Btu value of the waste, and levels of... hazardous waste has a total concentration of organic compounds listed in part 261, appendix VIII, of...

  12. 24 CFR 266.200 - Eligible projects.

    Science.gov (United States)

    2010-04-01

    ... being collected at unassisted projects in the market area that are similar in amenities and location to... assistance agreement or the unit rents being collected at unassisted projects in the market that are...

  13. 29 CFR 1910.266 - Logging operations.

    Science.gov (United States)

    2010-07-01

    ... employee wears foot protection, such as heavy-duty logging boots that are waterproof or water repellant...(c)(3). (ii) The employer shall notify the power company immediately if a felled tree makes contact... and ice accumulation, the wind, the lean of tree, dead limbs, and the location of other trees,...

  14. 39 CFR 266.9 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ...) because the systems contain information pertaining to the enforcement of criminal laws. The reasons for... the material. The reasons for exemption follow: (i) These systems contain questions and answers to... would be necessary if questions or answers were available for inspection and copying....

  15. 12 CFR 26.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... a monopoly or substantial lessening of competition and would not present safety and soundness... apply a rebuttable presumption that an interlock will not result in a monopoly or substantial lessening...) of this section may continue so long as it does not result in a monopoly or substantial lessening...

  16. 49 CFR 266.19 - Environmental impact.

    Science.gov (United States)

    2010-10-01

    ... the applicant seek the Administrator's advice as to form and substance of the assessment for the... environmental effects. The environmental assessment and all documents used as a basis for the assessment shall... and prudent alternative to the use of such land; and (ii) The project includes all planning...

  17. 24 CFR 266.205 - Ineligible projects.

    Science.gov (United States)

    2010-04-01

    ... services such as room service for food and beverages, maid service, furnishing and laundering of linens, or... kitchens and dining rooms with food service or mandatory services. (d) Nursing homes or intermediate care facilities. Nursing homes and intermediate care facilities licensed and regulated by State or...

  18. 1935 15' Quad #266 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  19. Dicty_cDB: VFA266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available e, mRNA sequence. 92 3e-16 3 AW217896 |AW217896.1 EST296610 tomato flower buds, anthesis, Cornell University...|AI778006.1 EST258885 tomato susceptible, Cornell Lycopersicon esculentum cDNA clone cLES3N17, mRNA sequence..., mRNA sequence. 92 3e-15 2 AW219042 |AW219042.1 EST301524 tomato root during/after fruit set, Cornell...quence. 92 3e-15 2 BG642411 |BG642411.1 EST355887 tomato flower buds, anthesis, Cornell University Lycopersi

  20. 75 FR 266 - Customs and Border Protection's Bond Program

    Science.gov (United States)

    2010-01-05

    ...] [FR Doc No: E9-30920] DEPARTMENT OF HOMELAND SECURITY Bureau of Customs and Border Protection DEPARTMENT OF THE TREASURY 19 CFR Parts 101, 113, and 133 [Docket No. USCBP-2006-0013] RIN 1505-AB54 Customs and Border Protection's Bond Program AGENCIES: Customs and Border Protection, Department of...

  1. Dicty_cDB: CHC266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ---RILINKEIQNF*xq*hlgqfqxnglyfxtkxfg*xgxhyqskgc*w*kxhsigxccw ccnxix*qxkrxqxtxikiftsexnl*slxrsxkxxltrxgxfgne...gsnltnctk*nske*ifkqrntiyqqivypf--- ---RILINKEIQNF*xq*hlgqfqxnglyfxtkxfg*xgxhyqskgc*w*kxhsigxccw ccnxix*qxkrx

  2. Dicty_cDB: SSL266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available NXGDRXNVYXDFSYFFFFFKKKKQTKQVYFHFFFFKKKAIL S*minkeiffqfinpikl*iiniffiqkkkkkkk Translated Amino Acid sequence ...FSYFFFFFKKKKQTKQVYFHFFFFKKKAIL S*minkeiffqfinpikl*iiniffiqkkkkkkk Frame C: qiinth

  3. Dicty_cDB: AFH266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CA813481 |CA813481.1 CA48LN10IF-E8 Cabernet Sauvignon Leaf - CA48LN Vitis vinifera cDNA clone CA48LN10IF-E8 ...5', mRNA sequence. 64 5e-07 2 CB341828 |CB341828.2 CA32EN0002_IIIbF_E01 Cabernet

  4. 40 CFR Appendix IV to Part 266 - Reference Air Concentrations*

    Science.gov (United States)

    2010-07-01

    ... No. RAC (ug/m3) Acetaldehyde 75-07-0 10 Acetonitrile 75-05-8 10 Acetophenone 98-86-2 100 Acrolein 107...-01-8 30 Carbon Disulfide 75-15-0 200 Chloral 75-87-6 2 Chlorine (free) 0.4 2-Chloro-1,3-butadiene 126... Cyanide (free) 57-12-15 20 Cyanogen 460-19-5 30 Cyanogen Bromide 506-68-3 80 Di-n-butyl Phthalate...

  5. Dicty_cDB: VHA266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available GS-28-01-01-1P6-2P0KB marine metagenome genomic clone 1061002356772 3', genomic survey...rine metagenome genomic clone 1061005731710 3', genomic survey sequence. 62 1e-14 2 EK163249 |EK163249.1 109...clone 1061005731710 5', genomic survey sequence. 62 1e-14 2 EJ250666 |EJ250666.1 1095344030991 Global-Ocean-...Sampling_GS-27-01-01-1P8-2P0KB marine metagenome genomic clone 1061005477347 5', genomic survey sequence. 48...nomic clone 1061005784059 5', genomic survey sequence. 68 3e-10 3 EJ059409 |EJ059

  6. 40 CFR 35.266 - Maintenance of effort.

    Science.gov (United States)

    2010-07-01

    ... maintain its aggregate expenditures from all other sources for programs for controlling nonpoint pollution and improving the quality of the State's waters at or above the average level of such expenditures...

  7. Dicty_cDB: SHK266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available S Schistosoma japonicum cDNA, mRNA sequence. 56 0.001 1 CV682907 |CV682907.1 service43_H06_sjs2-16-2B11-T3 S...JS Schistosoma japonicum cDNA, mRNA sequence. 56 0.001 1 CV682854 |CV682854.1 service30_G09_sjs2-14-10C09-T3

  8. Dicty_cDB: SFJ266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available tpvqyenvkstvpaifdiai tiktdaknti*neindniyasndhrx*txxxxixxxxxxxxxxxxxxxxxxlxxxxxx--...k*iinmmnptktir**inwy*ksge*yqyy*ytcti*kc*insssni*hcyy hkn*c*kyhik*nq**yicfk*psxmnxtxxxxxxxxxxxxxxxxxxxxxxxxxxxx

  9. 78 FR 266 - Radio Broadcasting Services; Maysville, GA

    Science.gov (United States)

    2013-01-03

    ...-270; RM-11676; DA 12-2024] Radio Broadcasting Services; Maysville, GA AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: The Audio Division, at the request of Appalachian Broadcasting... Review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Radio, Radio...

  10. 7 CFR 1944.266 - Other Federal requirements.

    Science.gov (United States)

    2010-01-01

    ... 109); (2) The Affirmative Fair Housing Marketing Program requirements of 24 CFR part 200, subpart M, and the implementing regulations at 24 CFR part 108; and (3) Racial and ethnic collection requirements—Recipients must maintain current data on the race, ethnicity and gender of program applicants...

  11. Dicty_cDB: SLC266 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ne) Dictyostelium discoideum cysteine prot... 214 9e-55 AY332271_1( AY332271 |pid:none) Tenebrio molitor cat...hepsin-L-like ... 142 5e-33 AY207373_1( AY207373 |pid:none) Tenebrio molitor cath

  12. Secondary Prevention for Breast Cancer:Evaluation on Effect of Breast Self-examination in 266 064 Women in Shanghai%乳腺癌二级预防——上海266064名妇女乳房自我检查效果的评估

    Institute of Scientific and Technical Information of China (English)

    高道利; 杨如法; 王文婉; 胡永伟; 陈范良; 潘雷达; 袁亚; 郁领娣; 钱锋; 姚引珍

    2008-01-01

    [目的]论证及评估乳房自我检查(BSE)作为乳腺癌二级预防的作用及推广价值.[方法]大样本前瞻性随机对照研究.自1989年10月起,上海纺织系统519个单位266 064名年龄在30~64岁妇女,按单位整体随机进入指导组(BSE组,132979人)或对照组(133 085人).BSE组对人组妇女进行强化型BSE教育和指导5年,持续密切观察两组人群乳房疾病的发生、手术和生存状况7年.对乳腺癌患者随访到2001年12月.实际随访12年.统计分析采用Kaplan-Meier方法、Log-Rank检验以及Cox模型.[结果]BSE组检出乳腺癌864例,死亡133例;对照组检出乳腺癌896例,死亡130例.两组检出率分别为70.6/10万、72.6/10万(P>0.05),两组累积死亡率分别为150.6/10万、120.6/10万(P=0.72).肿块直径≤2.0cm,两组检出率分别为48.0%、44.6%(P=0.07);0+Ⅰ期病例分别为29.7%、27.6%(P=0.39),两组差异均无统计学意义.良性肿块检出率分别为2.3%、1.2%,特别是纤维腺瘤检出率及肿块大小,两组差异有显著性(P<0.01).[结论]对女性人群开展BSE教育和指导不能提高乳腺癌的早期诊断率和降低死亡率:在指导组存在过度诊断,造成过多的乳房良性病变被手术切除.

  13. 20 CFR 266.4 - Information considered in selecting a representative payee.

    Science.gov (United States)

    2010-04-01

    ... Board may consider such factors as the following: (a) The relationship of the person to the annuitant, including the type of relationship, e.g., family or legal guardianship; degree of relationship, if the...'s identification has already been established to the satisfaction of the Board; (g) Whether...

  14. Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H266

    DEFF Research Database (Denmark)

    Marthaler, Adele Gabriele; Schmid, Benjamin; Tubsuwan, Alisa

    2016-01-01

    Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. Here, we demonstrate the generation of an induced pluripotent stem cell...

  15. Brazil and the United States: The Need for Strategic Engagement (Strategic Forum, Number 266, March 2011)

    Science.gov (United States)

    2011-03-01

    Kerr, Bill McIlhenny, Frank Mora , Nicholas Rostow, Phillip C. Saunders, and Paulo Sotero for their support and criticism, but the views ex- pressed...264, february 2011) Conventional Prompt global Strike: Strategic asset or Unusable Liability? M. elaine Bunn and Vincent a. Manzo (Center for

  16. 40 CFR Appendix Ix to Part 266 - Methods Manual for Compliance With the BIF Regulations

    Science.gov (United States)

    2010-07-01

    ...) by the attenuation of the beam by the gas in its path. 2.1.2.3Instrument Measurement Range. The... excess of 10 percent between the average concentration in the duct or stack and the concentration at...

  17. SU-E-J-266: A Pitfall of a Deformable Image Registration in Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Sugawara, Y [The National Center for Global Health and Medicine, Shinjuku, Tokyo (Japan); Tachibana, H [The National Cancer Center Hospital East, Kashiwa, Chiba (Japan); Moriya, S [Komazawa University, Setagaya, Tokyo (Japan); Sawant, A [UT Southwestern Medical Center, Dallas, TX (United States)

    2014-06-01

    Purpose: For four-dimensional (4D) planning and adaptive radiotherapy, deformable image registration (DIR) is needed and the accuracy is essential. We evaluated the accuracy of one free-downloadable DIR software library package (NiftyReg) and one commercial DIR software (MIM) in lung SBRT cancer patients. Methods: A rigid and non-rigid registrations were implemented to our in-house software. The non-rigid registration algorithm of the NiftyReg and MIM was based on the free-form deformation. The accuracy of the two software was evaluated when contoured structures to peak-inhale and peak-exhale 4DCT image data sets were measured using the dice similarity coefficient (DSC). The evaluation was performed in 20 lung SBRT patients. Results: In our visual evaluation, the eighteen cases show good agreement between the deformed structures for the peak-inhale phase and the peak-exhale phase structures (more than 0.8 DSC value). In the evaluation of the DSC in-house software, averaged DSC values of GTV and lung, heart, spinal cord, stomach and body were 0.862 and 0.979, 0.932, 0.974, 0.860, 0.998, respectively. As the Resultof the registration using the MIM program in the two cases which had less than 0.7 DSC value when analyzed using the in-house software, the DSC value were improved to 0.8. The CT images in a case with low DSC value shows the tumor was surrounded by the structure with the similar CT values, which were the chest wall or the diaphragm. Conclusion: Not only a free-downloadable DIR software but also a commercial software may provide unexpected results and there is a possibility that the results would make us misjudge the treatment planning. Therefore, we recommend that a commissioning test of any DIR software should be performed before clinical use and we should understand the characteristics of the software.

  18. The NMR restraints grid at BMRB for 5,266 protein and nucleic acid PDB entries.

    NARCIS (Netherlands)

    Doreleijers, J.F.; Vranken, W.F.; Schulte, C.; Lin, J.; Wedell, J.R.; Penkett, C.J.; Vuister, G.W.; Vriend, G.; Markley, J.L.; Ulrich, E.L.

    2009-01-01

    Several pilot experiments have indicated that improvements in older NMR structures can be expected by applying modern software and new protocols (Nabuurs et al. in Proteins 55:483-186, 2004; Nederveen et al. in Proteins 59:662-672, 2005; Saccenti and Rosato in J Biomol NMR 40:251-261, 2008). A recen

  19. 24 CFR 266.120 - Actions for which sanctions may be imposed.

    Science.gov (United States)

    2010-04-01

    ... matter under this part. (b) Assignment or transfer of interest in any insured mortgage not in accord with... mortgage insurance premiums on a timely basis or failure to refund or credit mortgagor's accounts with overpaid mortgage insurance premiums....

  20. 40 CFR Appendix V to Part 266 - Risk Specific Doses (10−5)

    Science.gov (United States)

    2010-07-01

    ...−04 4.5E−02 1,4-Dioxane 123-91-1 1.4E−06 7.1E+00 Epichlorohydrin 106-89-8 1.2E−06 8.3E+00 Ethylene.... Unit risk (m3/μg) RsD (μg/m3) Acrylamide 79-06-1 1.3E−03 7.7E−03 Acrylonitrile 107-13-1 6.8E−05 1.5E−01 Aldrin 309-00-2 4.9E−03 2.0E−03 Aniline 62-53-3 7.4E−06 1.4E+00 Arsenic 7440-38-2 4.3E−03 2.3E−03...

  1. 40 CFR Appendix Viii to Part 266 - Organic Compounds for Which Residues Must Be Analyzed

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Organic Compounds for Which Residues...—Organic Compounds for Which Residues Must Be Analyzed Volatiles Semivolatiles Benzene Bis(2-ethylhexyl... those compounds that do not have an established F039 nonwastewater concentration limit....

  2. 7 CFR 2.66 - Administrator, Cooperative State Research, Education, and Extension Service.

    Science.gov (United States)

    2010-01-01

    ... productivity; development of new food, fiber, and energy sources; agricultural energy use and production... address concerns about the environmental effects of biotechnology (7 U.S.C. 5921). (38) (39) Administer a... to agriculture, uses of solar energy with respect to agriculture, home economics, and rural energy...

  3. 77 FR 266 - Fresh Garlic From the People's Republic of China: Initiation of New Shipper Reviews

    Science.gov (United States)

    2012-01-04

    ... International Trade Administration Fresh Garlic From the People's Republic of China: Initiation of New Shipper...) under the antidumping duty order on fresh garlic from the People's Republic of China (PRC), meet the... published the antidumping duty order on fresh garlic from the PRC in the Federal Register on November...

  4. 40 CFR 266.210 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-07-01

    ... under subsection 274b of the Atomic Energy Act of 1954, as amended (68 Stat. 919), to assume... sufficient to form a critical mass. Certified delivery means certified mail with return receipt requested, or... regulated by NRC, or NRC Agreement States, under authority of the Atomic Energy Act of 1954, as amended....

  5. Properties of Group Five and Group Seven transactinium elements

    Energy Technology Data Exchange (ETDEWEB)

    Wilk, Philip A.

    2001-05-01

    The detection and positive identification of the short-lived, low cross section isotopes used in the chemical studies of the heaviest elements are usually accomplished by measuring their alpha-decay, thus the nuclear properties of the heaviest elements must be examined simultaneously with their chemical properties. The isotopes 224 Pa and 266,267 Bh have been studied extensively as an integral part of the investigation of the heaviest members of the groups five and seven of the periodic table. The half-life of 224 Pa was determined to be 855 plus/minus19 ms by measuring its alpha-decay using our rotating wheel, solid state detector system at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. Protactinium was produced by bombardment of a bismuth target. New neutron rich isotopes, 267 Bh and 266 Bh, were produced in bombardments of a 249 Bk target and their decay was observed using the rotating wheel system. The 266 Bh that was produced decays with a half-life of approximately 1 s by emission of alpha particles with an average energy of 9.25 plus/minus 0.03 MeV. 267 Bh was observed to decay with a 17 s half-life by emission of alpha-particles with an average energy of 8.83 plus/minus 0.03 MeV. The chemical behavior of hafnium, Ha (element 105) was investigated using the fast on-line continuous liquid extraction and detection system SISAK-LISSY. Hafnium was not observed in this experiment following transport and extraction. Protactinium was used as on-line test of the apparatus to determine the experimental efficiency of the entire system. Unfortunately, the amount of protactinium observed after the extraction, compared to the amount produced, was extremely small, only 2.5%. The extraction of the protactinium isotope indicated the efficiency of the apparatus was too low to observe the extraction of hafnium. The chemical behavior of oxychloride compounds of bohrium was investigated by isothermal gas adsorption chromatography in a quartz column at 180, 150

  6. Study on multi-photon ionization mass spectra of triethylamine at the laser of 266 nm%266 nm激光下三乙胺分子多光子电离质谱研究

    Institute of Scientific and Technical Information of China (English)

    程起元; 周留柱; 孔祥和; 董嫣然; 尹新

    2012-01-01

    利用YAG激光器输出的四倍频激光对三乙胺分子的共振增强双光子电离过程进行了研究,获得了三乙胺分子的飞行时间质谱,母体离子及碎片离子信号达29种之多.对碎片离子(C2H5)2N+CH2(86+)异常漂移做了分析,发现了异常漂移是由于离子信号强度过强时,86+之前的25种离子对其25次瞬间减速效应强于之后的3种离子对其3次瞬间加速效应造成的.%Using the four-harmonic YAG laser as excitation source, studying on the process of resonance-enhanced two-photon ionization of triethylamine, the time-of-flight mass spectra of triethylamine is obtained. Parent ion and fragment ion reach as much as 29 kinds. Analyzing the abnormal variation of (C2H5)2N+CH2(86+) show that when the signal ions' intensity are very strong, the 25-times instantaneous deceleration effort of 25 kinds of ions before 86+ are stronger than 3-times deceleration effort of 3 kinds of ions after 86+.

  7. NUCLEAR CHEMISTRY: Element 107 Leaves the Table Unturned.

    Science.gov (United States)

    Service, R F

    2000-08-25

    This week, an international team of chemists reported on the first successful analysis of the chemical properties of bohrium, element 107. The results matched predictions, postponing scientists' hopes of seeing interesting deviations from theory among ultraheavy elements.

  8. Automatisch snelheidstoezicht op de N266 in Noord-Brabant : evaluatie van het effect op lange termijn.

    NARCIS (Netherlands)

    Oei, H.-l. Minnen, J. van & Goldenbeld, C.

    1995-01-01

    Four road stretches having a speed limit of 80 km/h were equipped with an electronic speed management system, consisting of a fixed warning sign, a switchable sign only showing when cars were speeding and automatic speed enforcing using radar and camera from road side mounted posts. This system was

  9. Social Participation: the construction of democracy in Brazilian health - doi:10.5020/18061230.2011.p266

    Directory of Open Access Journals (Sweden)

    Cibelle Cristina da Silva Santos

    2012-01-01

    Full Text Available Objective: To verify the theoretical construction of the terms “social participation” and “social control” relating them to the process of construction of democracy in Brazilian health. Methods: A bibliographic survey conducted in Lilacs and Scielo databases in the period of 2002 to 2009, using the following descriptors: Unified Health System (SUS, Participation and Social Control, Health Policy. Results: The post-1988 Constitution period brought the democratization and decentralization of social policy making room for countless experiences of popular participation. The SUS was created to meet the demands of the population in face of that historic moment. But today, more than twenty years of its creation, the lack of understanding of its guiding principles by health professionals and the population consists in a challenge to its effectiveness. Conclusions: Despite the institutionalization of participation, a culture of non-participation and the lack of knowledge of its instruments are significant barriers to the practice of social participation in health, which represents a complex work that needs to be developed with active Citizen-State relationship.

  10. 40 CFR Appendix Vii to Part 266 - Health-Based Limits for Exclusion of Waste-Derived Residues*

    Science.gov (United States)

    2010-07-01

    .... Concentration limits for residues (mg/kg) Acetonitrile 75-05-8 2xE−01 Acetophenone 98-86-2 4xE+00 Acrolein 107... Constituent CAS No. Concentration limits (mg/L) Antimony 7440-36-0 1xE+00 Arsenic 7440-38-2 5xE+00 Barium 7440...-92-1 5xE+00 Mercury 7439-97-6 2xE−01 Nickel 7440-02-0 7xE+01 Selenium 7782-49-2 1xE+00 Silver...

  11. The prognostic value of positron emission tomography in non-small cell lung cancer : Analysis of 266 cases

    NARCIS (Netherlands)

    Kramer, H.; Post, W.J.; Pruim, J.; Groen, H.J.M.

    2006-01-01

    Positron emission tomography (PET) is more accurate than computed tomography (CT) in the staging of non-small cell lung cancer (NSCLC). We analyzed the prognostic value of PET for survival in NSCLC patients. Methods: Consecutive patients with proven NSCLC with PET for staging were selected. Staging

  12. Comparison of photosensitivity in germanium doped silica fibers using 244 nm and 266 nm continuous wave lasers

    DEFF Research Database (Denmark)

    Jensen, Jesper Bo; Varming, Poul; Liu, B.;

    2001-01-01

    Diode pumped continuous-wave UV lasers offer an interesting alternative to frequency doubled argon-ion lasers. We report the first photosensitivity comparison using these lasers on deuterium loaded standard telecommunication fibers and unloaded experimental fibers....

  13. Maddy-Weitzman Bruce and Zisenwine Daniel (eds., The Maghrib in the New Century, Gainesville, University of Florida Press, 2007, 266 p.

    Directory of Open Access Journals (Sweden)

    Francesco Cavatorta

    2009-09-01

    Full Text Available The book is a most welcome contribution on the state of the Maghreb at the start of the new century.  A number of external and domestic factors made the three countries examined in this edited volume (Morocco, Tunisia and Algeria primary candidates for successful processes of democratization in the Arab world in the late 1980s and early 1990s. Morocco, despite the significant executive powers of the monarchy and the authoritarianism of the années de plomb, always displayed a degree of politi...

  14. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266

    DEFF Research Database (Denmark)

    Marthaler, Adele Gabriele; Tubsuwan, Alisa; Schmid, Benjamin

    2016-01-01

    Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. We have successfully generated bona fide induced pluripotent stem cel...

  15. Generation of an isogenic, gene-corrected control cell line of the spinocerebellar ataxia type 2 patient-derived iPSC line H266

    DEFF Research Database (Denmark)

    Marthaler, Adele G; Tubsuwan, Alisa; Schmid, Benjamin;

    2016-01-01

    Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. We have successfully generated bona fide induced pluripotent stem cell...

  16. Archaeological Investigations at the Lewis Site (3LE266): A Twentieth- Century Black Owned Farmstead on the St. Francis Floodway, Lee County, Arkansas

    Science.gov (United States)

    1992-09-01

    Arkansas Archeological Survey Research Series 21. Fayetteville. Stine, Linda France 1990 Social Inequality and Turn-of-the-Century Farmsteads: Issues of...University, Pullman , Washington. 1989 - M.A., Anthropology, Memphis State University, Memphis, Tennessee. I Areas of Specialization Ceramic and Lithic Analysis...Department of Anthropology, Washington State University, Pullman , Washington. 1988a Perspectives on Emerging Chiefdoms: A Comparative Analysis. Paper

  17. Jelidi Charlotte, Fès, la fabrication d'une ville nouvelle (1912-1956, Lyon, ENS Editions, 2012, 266 p.

    Directory of Open Access Journals (Sweden)

    Manon Istasse

    2013-07-01

    Full Text Available Le segment d'histoire de l'architecture et de l'urbanisme abordé par Charlotte Jelidi, à savoir la période du Protectorat français (1912-1956 au Maroc, est une pierre à l’édifice des travaux réalisés sur les villes nouvelles marocaines, leur construction et leur évolution. Les villes nouvelles sont ces villes construites durant le Protectorat français, suivant la planification urbaine définie par Lyautey et son administration. Ces villes étaient majoritairement destinées aux Occidentaux, com...

  18. Challand Benoît, Palestinian Civil Society. Foreign donors and the power to promote and exclude, London, Routledge, 2009, 266 p.

    Directory of Open Access Journals (Sweden)

    Daniel Meier

    2010-01-01

    Full Text Available L’ouvrage de Benoît Challand a pour objet la société civile en tant qu’elle est promue par les institutions internationales. En l’inscrivant dans le contexte palestinien, il se demande si l’aide internationale y a réellement permis le développement d’une telle société civile. L’ouvrage repose donc sur un double enjeu, à la fois théorique et empirique : qu’entendre par « société civile » et comment cerner l’efficacité de sa promotion en Palestine ? Ce thème est au cœur de plusieurs colloques d...

  19. SU-E-T-266: Development of Evaluation System of Optimal Synchrotron Controlling Parameter for Spot Scanning Proton Therapy with Multiple Gate Irradiations in One Operation Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, T; Fujii, Y [Hokkaido University Hospital, Sapporo, Hokkaido (Japan); Hitachi Ltd., Hitachi-shi, Ibaraki (Japan); Miyamoto, N; Matsuura, T; Takao, S; Matsuzaki, Y [Hokkaido University Hospital, Sapporo, Hokkaido (Japan); Koyano, H; Shirato, H [Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido (Japan); Nihongi, H; Umezawa, M; Matsuda, K [Hitachi Ltd., Hitachi-shi, Ibaraki (Japan); Umegaki, K [Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido (Japan)

    2015-06-15

    Purpose: We have developed a gated spot scanning proton beam therapy system with real-time tumor-tracking. This system has the ability of multiple-gated irradiation in a single synchrotron operation cycle controlling the wait-time for consecutive gate signals during a flat-top phase so that the decrease in irradiation efficiency induced by irregular variation of gate signal is reduced. Our previous studies have shown that a 200 ms wait-time is appropriate to increase the average irradiation efficiency, but the optimal wait-time can vary patient by patient and day by day. In this research, we have developed an evaluation system of the optimal wait-time in each irradiation based on the log data of the real-time-image gated proton beam therapy (RGPT) system. Methods: The developed system consists of logger for operation of RGPT system and software for evaluation of optimal wait-time. The logger records timing of gate on/off, timing and the dose of delivered beam spots, beam energy and timing of X-ray irradiation. The evaluation software calculates irradiation time in the case of different wait-time by simulating the multiple-gated irradiation operation using several timing information. Actual data preserved in the log data are used for gate on and off time, spot irradiation time, and time moving to the next spot. Design values are used for the acceleration and deceleration times. We applied this system to a patient treated with the RGPT system. Results: The evaluation system found the optimal wait-time of 390 ms that reduced the irradiation time by about 10 %. The irradiation time with actual wait-time used in treatment was reproduced with accuracy of 0.2 ms. Conclusion: For spot scanning proton therapy system with multiple-gated irradiation in one synchrotron operation cycle, an evaluation system of the optimal wait-time in each irradiation based on log data has been developed. Funding Support: Japan Society for the Promotion of Science (JSPS) through the FIRST Program.

  20. A Compact, Solid-State UV (266 nm) Laser System Capable of Burst-Mode Operation for Laser Ablation Desorption Processing

    Science.gov (United States)

    Arevalo, Ricardo, Jr.; Coyle, Barry; Paulios, Demetrios; Stysley, Paul; Feng, Steve; Getty, Stephanie; Binkerhoff, William

    2015-01-01

    Compared to wet chemistry and pyrolysis techniques, in situ laser-based methods of chemical analysis provide an ideal way to characterize precious planetary materials without requiring extensive sample processing. In particular, laser desorption and ablation techniques allow for rapid, reproducible and robust data acquisition over a wide mass range, plus: Quantitative, spatially-resolved measurements of elemental and molecular (organic and inorganic) abundances; Low analytical blanks and limits-of-detection ( ng g-1); and, the destruction of minimal quantities of sample ( g) compared to traditional solution and/or pyrolysis analyses (mg).

  1. Analytical results and sample locality map of heavy-mineral-concentrate and rock samples from the Castle Peaks Wilderness Study Area (CDCA- 266), San Bernardino County, California

    Science.gov (United States)

    Adrian, B.M.; Frisken, J.G.; Malcolm, M.J.; Crock, J.G.

    1986-01-01

    The report presents water-quality and geohydrologic information for 106 public water-supply wells in Illinois. These wells were sampled during April to December 1984 as part of a pilot program to develop a ground-water observation network in the State. The pilot program was designed to sample single-aquifer wells from three major aquifer systems--(1) sand and gravel, both confined and unconfined; (2) Silurian dolomite; and (3) the Ironton-Galesville deep sandstone. Data are tabulated for water temperature, pH, specific conductance, oxidation-reduction potential, ammonia nitrogen, nitrate + nitrite nitrogen, phosphorus, silica, arsenic, lead, mercury, fluoride, chloride, sulfate, cyanide, phenols, selenium, residue on evaporation at 180 degrees Celsius, alkalinity, calcium, magnesium, sodium, potassium, barium, boron, beryllium, cadmium, chormium, copper, cobalt, iron, aluminum, manganese, nickel, silver, strontium, vanadium, zinc, and selected geohydrologic information.

  2. Odd-Z Transactinide Compound Nucleus Reactions Including the Discovery of 260Bh

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Sarah L. [Univ. of California, Berkeley, CA (United States)

    2008-01-01

    Several reactions producing odd-Z transactinide compound nuclei were studiedwith the 88-Inch Cyclotron and the Berkeley Gas-Filled Separator at the Lawrence Berkeley National Laboratory. The goal was to produce the same compound nucleus ator near the same excitation energy with similar values of angular momentum via differentnuclear reactions. In doing so, it can be determined if there is a preference in entrancechannel, because under these experimental conditions the survival portion of Swiatecki, Siwek-Wilcznska, and Wilczynski's"Fusion By Diffusion" model is nearly identical forthe two reactions. Additionally, because the same compound nucleus is produced, theexit channel is the same. Four compound nuclei were examined in this study: 258Db, 262Bh, 266Mt, and 272Rg. These nuclei were produced by using very similar heavy-ion induced-fusion reactions which differ only by one proton in the projectile or target nucleus (e.g.: 50Ti + 209Bi vs. 51V + 208Pb). Peak 1n exit channel cross sections were determined for each reaction in each pair, and three of the four pairs' cross sections were identical within statistical uncertainties. This indicates there is not an obvious preference of entrancechannel in these paired reactions. Charge equilibration immediately prior to fusionleading to a decreased fusion barrier is the likely cause of this phenomenon. In addition to this systematic study, the lightest isotope of element 107, bohrium, was discovered in the 209Bi(52Cr,n) reaction. 260Bh was found to decay by emission of a 10.16 MeV alpha particle with a half-life of 35$+19\\atop{-9}$ ms. The cross section is 59 pb at an excitation energy of 15.0 MeV. The effect of the N = 152 shell is also seen in this isotope's alpha particle energy, the first evidence of such an effect in Bh. All reactions studied are also compared to model predictions by Swiatecki

  3. Glycogen storage disease type Ia : four novel mutations (175delGG, R170X, G266V and V338F) identified. Mutations in brief no. 220. Online

    NARCIS (Netherlands)

    Rake, J P; ten Berge, A M; Verlind, E; Visser, G; Niezen-Koning, K E; Buys, C H; Smit, G P; Scheffer, H

    1999-01-01

    Deficient activity of glucose-6-phosphatase (G6Pase) causes glycogen storage disease type Ia (GSD Ia). We analysed the G6Pase gene of 16 GSD Ia patients using single strand conformation polymorphism (SSCP) analysis prior to automated sequencing of exon(s) revealing an aberrant SSCP pattern. In all G

  4. La urbe global y el gobierno de la vida humana. Coordinadores: Castor M.M. Bartolomé Ruiz y Rubén Alberto Duarte Cuadros. Colombia: Editorial Universidad Libre, 2012, 266 pp

    Directory of Open Access Journals (Sweden)

    Omar Huertas Díaz

    2012-07-01

    Full Text Available El objetivo del libro mediante los conocimientos filosóficos que se manejan y los planteamientos políticos que se utilizan es buscar una minimización de abusos de derechos humanos, observando los casos presentados en Colombia, el abuso de poder de los gobernadores y entes militares en estos últimos años. Es por eso que los autores mediante sus ponencias plantean o presentan una revisión del conflicto latinoamericano, de forma que se pueda visualizar holísticamente un problema y unas posibles soluciones.

  5. 75 FR 11740 - S-Abscisic Acid, (S)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-1-cyclohex-2-enyl)-3-methyl-penta-(2Z,4E...

    Science.gov (United States)

    2010-03-12

    ... hormone, ABA is known to be a strong actor in regulating plant growth by aiding in stress resistance... not appear to produce a toxic metabolite produced by other substances. For the purposes of...

  6. Multibeam collection for TN266: Multibeam data collected aboard Thomas G. Thompson from 2011-06-28 to 2011-07-27, departing from Seattle, WA and returning to Seattle, WA

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  7. Inés Ortiz Yam, De milperos a henenqueneros en Yucatán 1870-1937El Colegio de México, México DF, 2013, 266 p.

    OpenAIRE

    Baños Ramírez, Othón

    2014-01-01

    El cultivo comercial del henequén para exportación a gran escala marcó profundamente la historia contemporánea de Yucatán. De la exportación de fibra transitó a la agro-industria local. Constituyó el eje de un recorrido histórico que abarcó más de un siglo, desde mediados del siglo XIX hasta la última década del siglo XX. Esta obra que reseñaré da cuenta del proceso de transformación agraria que sufrió una porción del territorio yucateco en un trecho de aquel recorrido histórico, con el acica...

  8. The Sutton (13MA266) Site and the Townsites of Percy (13MA347) and Dunreath (13MA449): Data Recovery at Three Historic Sites, Lake Red Rock, Iowa

    Science.gov (United States)

    1989-07-01

    34Lucky Tiger/For Scalp/ Eczema & Dandruff/Lucky Tiger/Remedy Co./Kansas City, Mo." dating from post-1915 (Fike 1987:68) I and was likely from one of...that can’t root?--I tell you these Suffolks wont [sic] do--turn them into the woods, or out in a dog fennel lane to get a living, and they will lay...any account, will live without a shelter, and outrun the dogs , and average 200 pounds at 18 months old, with very little trouble--in short, Sir, we I

  9. SU-E-J-266: Cone Beam Computed Tomography (CBCT) Inter-Scan and Inter-Observer Tumor Volume Variability Assessment in Patients Treated with Stereotactic Body Radiation Therapy (SBRT) for Early Stage Non-Small Cell Lung Cancer (NSCLC)

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Y; Aileen, C; Kozono, D; Killoran, J; Wagar, M; Lee, S; Hacker, F; Aerts, H; Lewis, J; Mak, R [Brigham and Women’s Hospital, Boston, MA (United States)

    2015-06-15

    Purpose: Quantification of volume changes on CBCT during SBRT for NSCLC may provide a useful radiological marker for radiation response and adaptive treatment planning, but the reproducibility of CBCT volume delineation is a concern. This study is to quantify inter-scan/inter-observer variability in tumor volume delineation on CBCT. Methods: Twenty earlystage (stage I and II) NSCLC patients were included in this analysis. All patients were treated with SBRT with a median dose of 54 Gy in 3 to 5 fractions. Two physicians independently manually contoured the primary gross tumor volume on CBCTs taken immediately before SBRT treatment (Pre) and after the same SBRT treatment (Post). Absolute volume differences (AVD) were calculated between the Pre and Post CBCTs for a given treatment to quantify inter-scan variability, and then between the two observers for a given CBCT to quantify inter-observer variability. AVD was also normalized with respect to average volume to obtain relative volume differences (RVD). Bland-Altman approach was used to evaluate variability. All statistics were calculated with SAS version 9.4. Results: The 95% limit of agreement (mean ± 2SD) on AVD and RVD measurements between Pre and Post scans were −0.32cc to 0.32cc and −0.5% to 0.5% versus −1.9 cc to 1.8 cc and −15.9% to 15.3% for the two observers respectively. The 95% limit of agreement of AVD and RVD between the two observers were −3.3 cc to 2.3 cc and −42.4% to 28.2% respectively. The greatest variability in inter-scan RVD was observed with very small tumors (< 5 cc). Conclusion: Inter-scan variability in RVD is greatest with small tumors. Inter-observer variability was larger than inter-scan variability. The 95% limit of agreement for inter-observer and inter-scan variability (∼15–30%) helps define a threshold for clinically meaningful change in tumor volume to assess SBRT response, with larger thresholds needed for very small tumors. Part of the work was funded by a Kaye award; Disclosure/Conflict of interest: Raymond H. Mak: Stock ownership: Celgene, Inc. Consulting: Boehringer-Ingelheim, Inc.

  10. Dicty_cDB: Contig-U09621-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 65 Query: 266 catcagattttaaatatgtttattcagttcancaaattgcaaatacaatttatnatgtac 325 ||...|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 266 catcagattttaaatatgtttattcagttcancaaatt...gcaaatacaatttatnatgtac 325 Query: 326 cagaaacaatcattttagaaagtattcantcaagattactttataaacgtcatggtattc 385 |||||...||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 326 cagaaacaatcattttagaaagtattcan...tta 95612 Query: 239 catattcaaatacatatacatattcaacatcagattttaaatatgtttattcagttcanc 298 ||||||||||||||||||||||

  11. Automatic Parallelization of Scientific Application

    DEFF Research Database (Denmark)

    Blum, Troels

    In my PhD work I show that it is possible to run unmodified Python/NumPy code on modern GPUs. This is done by using the Bohrium runtime system to translate the NumPy array operations into an array based bytecode sequence. Executing these byte-codes on two GPUs from different vendors shows great...... performance gains. Scientists working with computer simulations should be allowed to focus on their field of research and not spend excessive amounts of time learning exotic programming models and languages. We have with Bohrium achieved very promising results by starting out with a relatively simple approach....... This has lead to more specialized methods as I have shown with the work done with both specialized, and parametrizied kernels. Both have their benefits and recognizable use cases. We achieved clear performance benefits without any significant negative impact on overall application performance. Even...

  12. Battling memory requirements of array programming through streaming

    DEFF Research Database (Denmark)

    Kristensen, Mads Ruben Burgdorff; Avery, James Emil; Blum, Troels;

    2016-01-01

    A barrier to efficient array programming, for example in Python/NumPy, is that algorithms written as pure array operations completely without loops, while most efficient on small input, can lead to explosions in memory use. The present paper presents a solution to this problem using array streaming......, implemented in the automatic parallelization high-performance framework Bohrium. This makes it possible to use array programming in Python/NumPy code directly, even when the apparent memory requirement exceeds the machine capacity, since the automatic streaming eliminates the temporary memory overhead...... streaming, yielding corresponding improvements in speed and utilization of GPGPU-cores. The streaming-enabled Bohrium effortlessly runs programs on input sizes much beyond sizes that crash on pure NumPy due to exhausting system memory....

  13. Gclust Server: 61308 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 61308 DME_CG4139_24641394 Cluster Sequences - 266 Karl: Karl CG4139-PB, isoform B 2...er sequences Cluster Sequences Link to related sequences - Sequence length 266 Representative annotation Karl: Karl

  14. En la infancia los diagnósticos se escriben con lápiz. La patologización de las diferencias en la clínica y la educación. Untoiglich, Gisela, et al. /266 p. Buenos Aires: Noveduc. 2013.

    Directory of Open Access Journals (Sweden)

    Adriana Cristóforo

    2013-11-01

    Full Text Available El libro está organizado en cuatro partes, en función del eje temático que tienen los trabajos que integra cada una de ellas: Procesos de Patologización; Procesos diagnósticos en la infancia; Patologías psíquicas graves en la primera infancia; y Acerca de inclusiones y exclusiones. Sin embargo más allá de esta organización, el libro tiene una armonía que, a través de la diversidad, otorga coherencia al abordaje de un problema complejo como lo es el de los diagnósticos en la infancia. Precisamente es esa manera compleja de abordar el problema la que aporta uno de los valores del texto: las múltiples miradas, significaciones y expresiones que surgen del entrecruzamiento entre las distintas profesiones de los autores y las diversas inscripciones geográficas (Argentina, Brasil, Portugal. Asimismo tal diversidad geográfica muestra lo extendido del fenómeno de la patologización de la infancia y de los recursos que el mismo aplicapara perpetuarse, por ejemplo, las regulaciones de distinto estatuto legal que los Estados van estableciendo en relación a las instituciones de salud y educación.

  15. Comparing Patient Safety in Rural Hospitals by Bed Count

    Science.gov (United States)

    2005-01-01

    tomography; SPECT = single photon emission computed tomography; ESWL = extracorporeal shock - wave lithotripte Patient Safety by Rural Hospital Bed Count...Computed Tomography (SPECT), and Extracorporeal Shockwave Lithotripsy (ESWL). Relatively few rural hospitals provide cardiac services, with large...48) 3.0% (266) SPECT* 9.1% (154) 32.8% (64) 56.3% (48) 23.3% (266) Ultrasound 90.9% (154) 95.3% (64) 95.8% (48) 92.9% (266) Radiation therapy * 5.2

  16. Main: 3SC2 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 3SC2 小麦 Bread Wheat Triticum aestivum Serine Carboxypeptidase Ii Chains A And B Nam... 1WHS; X-ray; A=6-260, B=266-418.|PDB; 1WHT; X-ray; A=5-260, B=266-418.|PDB; 3SC2; X-ray; A=1-259, B=266-417...WHDAPRSMLPIYRELIAAGLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPWYDDQEVGGWSQVYKGLTLVSVRGAGHEVPLHRPRQALVLFQYFLQGKPMPGQTKNAT wheat_3SC2.jpg ...

  17. Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter

    Energy Technology Data Exchange (ETDEWEB)

    Gobrecht, J.; Gaeggeler, H.; Herlach, D.; Junker, K.; Kettle, P.-R.; Kubik, P.; Zehnder, A. [eds.

    2000-07-01

    lthough originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element {sup 107} Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.

  18. Gclust Server: 198526 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 198526 Cph_Cpha266_2719 Cluster Sequences - 188 hypothetical protein 1 1.00e-99 0.0... 0.0 0.0 6.67 0.0 0.0 Show 198526 Cluster ID 198526 Sequence ID Cph_Cpha266_2719 Link to cluster sequences C

  19. Gclust Server: 167161 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 167161 Cph_Cpha266_2053 Cluster Sequences - 287 hypothetical protein 1 1.00e-99 0.0... 0.0 0.0 6.67 0.0 0.0 Show 167161 Cluster ID 167161 Sequence ID Cph_Cpha266_2053 Link to cluster sequences C

  20. Gclust Server: 201799 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 201799 Cph_Cpha266_0888 Cluster Sequences - 84 hypothetical protein 1 1.00e-40 0.0 ...0.0 0.0 6.67 0.0 0.0 Show 201799 Cluster ID 201799 Sequence ID Cph_Cpha266_0888 Link to cluster sequences Cl

  1. Constituents of the brown alga Padina tetrastromatica (Hauck)-II

    Digital Repository Service at National Institute of Oceanography (India)

    Parameswaran, P.S.; Naik, C.G.; Das, B.; Kamat, S.Y.; Bose, A; Nair, M.S.R.

    Three terpenoids, (2R,4S)-4-acetoxy-2-hydroxy-2,6,6-trimethylcyclohexanone (1), 3'R,4'-[(2R,4S)-4-acetoxy-2-hydroxy-2,6,6-trimethylcyclohexylidene] but-3'-en-2'-one or apo-9'-fucoxanthinone (2) and loliolide (3) have been isolated from the CHCl sub...

  2. Gclust Server: 200005 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 200005 Cph_Cpha266_0212 Cluster Sequences - 92 hypothetical protein 1 1.00e-45 0.0 ...0.0 0.0 6.67 0.0 0.0 Show 200005 Cluster ID 200005 Sequence ID Cph_Cpha266_0212 Link to cluster sequences Cl

  3. Gclust Server: 200001 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 200001 Cph_Cpha266_0937 Cluster Sequences - 63 hypothetical protein 1 1.00e-28 0.0 ...0.0 0.0 6.67 0.0 0.0 Show 200001 Cluster ID 200001 Sequence ID Cph_Cpha266_0937 Link to cluster sequences Cl

  4. Oil Price Hike Boosts CNOOC Revenue%Oil Price Hike Boosts CNOOC Revenue

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Q1 production up 26.6 percent CNOOC Limited's first-quarter production increased 26.6 percent to 85.2 million barrels of oil equivalent compared with the same period last year. Output at the Jinzhou 25-1 project commenced in the first quarter, CNOOC sa

  5. Gclust Server: 193811 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 193811 Cph_Cpha266_1621 Cluster Sequences - 121 hypothetical protein 1 1.00e-60 0.0... 0.0 0.0 6.67 0.0 0.0 Show 193811 Cluster ID 193811 Sequence ID Cph_Cpha266_1621 Link to cluster sequences C

  6. Elm tree (Ulmus parvifolia) bark bioprocessed with Mycelia of Shiitake (Lentinus edodes) mushrooms in liquid Culture: Composition and mechanism of protection against allergic asthma in mice

    Science.gov (United States)

    The present study investigated the antiasthma effect of a bioprocessed Ulmus parvifolia bark extract (BPUBE) from Lentinus edodes liquid mycelia culture against allergic asthma biomarkers in U266B1 leukemia cells and OVA-sensitized/challenged mice. BPUBE suppressed total IgE release from U266B1 cel...

  7. Gclust Server: 170712 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 170712 Cph_Cpha266_1200 Cluster Sequences - 121 hypothetical protein 1 1.00e-60 0.0... 0.0 0.0 6.67 0.0 0.0 Show 170712 Cluster ID 170712 Sequence ID Cph_Cpha266_1200 Link to cluster sequences C

  8. Gclust Server: 170725 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 170725 Cph_Cpha266_1239 Cluster Sequences - 88 hypothetical protein 1 1.00e-40 0.0 ...0.0 0.0 6.67 0.0 0.0 Show 170725 Cluster ID 170725 Sequence ID Cph_Cpha266_1239 Link to cluster sequences Cl

  9. Forkyndelsesfrihed og straffelov

    DEFF Research Database (Denmark)

    Christoffersen, Lisbet

    2013-01-01

    Kan bibelens ord - eller Koranens for den sags skyld - være hate speech i straffelovens § 266 forstand?......Kan bibelens ord - eller Koranens for den sags skyld - være hate speech i straffelovens § 266 forstand?...

  10. Dicty_cDB: VFJ482 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available pid:none) Asterionella glacialis MAT mRNA fo... 266 4e-72 ( P50304 ) RecName: Ful...... 269 1e-72 (Q9FPL6) RecName: Full=S-adenosylmethionine synthetase 2; ... 266 2e-72 AB461922_1( AB461922 |

  11. Gclust Server: 194141 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 194141 Cph_Cpha266_1661 Cluster Sequences - 85 hypothetical protein 1 1.00e-40 0.0 ...0.0 0.0 6.67 0.0 0.0 Show 194141 Cluster ID 194141 Sequence ID Cph_Cpha266_1661 Link to cluster sequences Cl

  12. Gclust Server: 194137 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 194137 Cph_Cpha266_1611 Cluster Sequences - 138 hypothetical protein 1 1.00e-70 0.0... 0.0 0.0 6.67 0.0 0.0 Show 194137 Cluster ID 194137 Sequence ID Cph_Cpha266_1611 Link to cluster sequences C

  13. Progress report: 1988 walrus Pacific walrus harvest, health and welfare study Diomede, Alaska

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Between May 10 and June 29, 700 walrus were harvested by hunters from Little Diomede Island. Of these 266 (38%) were adult males, 394 (56%) were adult females and 40...

  14. Mars environment. Citations from the NTIS data base

    Science.gov (United States)

    Hundemann, A. S.

    1980-09-01

    Research dealing with atmospheric and surface properties of Mars is discussed. A few abstracts pertain to instrumentation used in the space exploration. This updated bibliography contains 266 citations, 9 of which are new entries to the previous edition.

  15. PHOTOSYNTHETIC ACTIVE RADIATION (PAR) profile data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN262 and others as part of the GB project from 1995-01-12 to 1995-06-04 (NODC Accession 0106520)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0106520 includes profile and physical data collected aboard the ENDEAVOR during cruises EN259, EN262, EN264, EN266 and EN267I in the North Atlantic...

  16. AcEST: BP919649 [AcEST

    Lifescience Database Archive (English)

    Full Text Available S+ P ++I Sbjct: 266 LSAIKVGQEVHGRVVKNDKLRNDIILSNAFVDMYAKCSRIKEARFIFDSM-PIRNVIAET 324 Query: 224 SLLTG 210 S+...AKDLLRSIPPSPDLIIWVSLLTGCKEYGN 192 C G+ N +++L ++ G L A + S+ +PD++ W SL+ G ++G Sbjct: 417 HCYALKTGLNCDTSVTNGLIDLYAKCGSLKTAHKIFDSM-

  17. CHLOROPHYLL A and PHAEOPIGMENTS profile data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN262 and others as part of the GB project from 1995-01-11 to 1995-06-16 (NODC Accession 0104395)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0104395 includes profile and biological data collected aboard the ENDEAVOR during cruises EN259, EN262, EN264, EN266 and EN267II in the North Atlantic...

  18. 77 FR 21986 - Agency Information Collection Activities; Proposed Collection; Comment Request

    Science.gov (United States)

    2012-04-12

    ... Scale, Youth 3,986 5 0.07 1,329 266 Second Edition (RCMAS-2). Reynolds Adolescent Depression Scale...: Staff as Caregiver. Staff as Caregiver--Follow-Up (MSSC-RS-F). Cultural Competence and Service...

  19. Review: Matthew Lange, Lineages of Despotism and Development: British Colonialism and State Power (2009 Besprechung: Matthew Lange, Lineages of Despotism and Development: British Colonialism and State Power (2009

    Directory of Open Access Journals (Sweden)

    Georg Schäfer

    2010-01-01

    Full Text Available Review of the monograph: Matthew Lange (2009, Lineages of Despotism and Development: British Colonialism and State Power, Chicago and London: The University of Chicago Press, ISBN 978-0-266-47068-9, 208 pp. Besprechung der Monographie: Matthew Lange (2009, Lineages of Despotism and Development: British Colonialism and State Power, Chicago and London: The University of Chicago Press, ISBN 978-0-266-47068-9, 208 Seiten

  20. Drug: D05006 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D05006 Drug Metizoline hydrochloride (USAN); Ellsyl (TN) C13H14N2S. HCl 266.0644 266.7896 D0500...ATIONS FOR TOPICAL USE R01AA Sympathomimetics, plain R01AA10 Metizoline D05006 Me...tizoline hydrochloride (USAN) CAS: 5090-37-9 PubChem: 47206733 LigandBox: D05006 NIKKAJI: J388.837A ATOM 17

  1. Th/U dating of marine and continental mollusk shell, and travertine samples in quaternary deposits in Morocco

    Science.gov (United States)

    Semghouli, S.; Choukri, A.; Cherkaoui El Moursli, R.; Jahjouh, E.; Chouak, A.; Ben Mohammadi, A.; Latiris, M.; Reyss, J.-L.; Plaziat, J. L.

    2001-06-01

    Th/U measurements by alpha spectrometry have been carried out on samples of quaternary deposits in Morocco Ages yielded by marine samples allow identification of two high sea levels: (1) Last Interglacial ˜133 ka (ii) Harounien sea level ˜266 ka. The scatter of ages around 133 and 266 ka has been discussed and corrected. For continental samples, the ages allowed identification of humid episodes during which these samples have been deposited.

  2. Older Veteran Digital Disparities: Examining the Potential for Solutions Within Social Networks

    OpenAIRE

    Luger, Tana M; Hogan, Timothy P; Richardson, Lorilei M; Cioffari, Lisa S; Harvey, Kimberly; Houston, Thomas K.

    2016-01-01

    Background Older adults typically have less access to the Internet than other age groups, and older Veterans may use the Internet even less due to economic and geographic reasons. Objective To explore solutions to this problem, our study examined older Veterans’ reported ability to access technology through their close social ties. Methods Data were collected via mail survey from a sample of Veterans aged 65 years and older (N=266). Results Nearly half (44.0%, 117/266) of the sample reported ...

  3. Index of Oral Histories Relating to Naval Research, Development, and Acquisition

    Science.gov (United States)

    1992-07-01

    Mentioned: Byrnes, CAPT James Parsons, RADIA William S. Lauritsen, Dr. Charles C. Sabin , Palmer Aubjects: China Lake pilot plant Michelson Laboratory...119 Seiler, Karl 30 Saalfeld, Dr. Frederick 355, 358 Selwyn, Dr. Philip 355, 358 Sabin , Palmer 266 Senter, Frank 31 Sagdahl, John 266 Sette, Dr...research 157 Lehman, John 222 Libby Board 47, 128 Jaimming devices 210 Life cycle support function 69 Jet Propulsion 308 Light airborne ASW vehicle 235 Jet

  4. Drug: D07791 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07791 Drug Desipramine (INN) C18H22N2 266.1783 266.3807 D07791.gif Antidepressant,... tricyclic Same as: C06943 ATC code: N06AA01 Tricyclic antidepressants serotonin transporter inhibitor [HSA:...ic biomarker: CYP2D6 [HSA:1565] map07027 Antidepressants map07234 Neurotransmitte...ine D07791 Desipramine (INN) USP drug classification [BR:br08302] Antidepressants

  5. Annual Gaseous Electronics Conference (39th) Held in Madison, Wisconsin on 7-10 October 1986. Program and Abstracts.

    Science.gov (United States)

    1986-01-01

    1400 WASHINGTON AVE. NELA PARK ALBANY NY 12222 CLEVELAND OH 44112 518-422-3814 BEBERMAN, JAMES BIGIO, LARRY UNIV.OF ILLINOIS GENERAL ELECTRIC GASEOUS...GENERAL ELECTRIC WRIGHT-PATTERSON NELA PARK AFB OH 45433 CLEVELAND OH 44112 513-255-2923 216-266-3213 GARSCADDEN, ALAN GISLASON, ERIC A. U.S.A.F. UNIV...NOBUAKI GENERAL ELECTRIC CO PROFESSOR NELA PARK TOKUSHIMA UNIVERSITY CLEVELAND OH 44112 TECHNICAL COLLEGE 216-266-8971 MINAMI-JOSANJIMA TOKUSHIMA

  6. Short Communication on "Direct compositional quantification of (U-Th)O2 - MOX nuclear fuel using ns-UV-LIBS and chemometric regression models"

    Science.gov (United States)

    Singh, Manjeet; Sarkar, Arnab; Mao, Xianglei; Russo, Richard E.

    2017-02-01

    The determination of uranium with composition varying from 0% to 35 wt% in (Th-U)O2 mixed oxide fuel using laser induced breakdown spectroscopy (LIBS) utilizing partial least square regression (PLSR) has been demonstrated. Good agreement between expected and experiment results using 266 nm, 532 nm and 1064 nm was shown. The analytical results at 266 nm of 2-3% precision and ∼1% accuracy (bias) satisfy the acceptance criteria range for chemical analysis in the nuclear industry.

  7. The comparative effect of an addition of a surface term to the Woods-Saxon potential on the thermodynamics of a nucleon

    CERN Document Server

    Lütfüoğlu, B C

    2016-01-01

    In this study, we reveal the difference between Woods-Saxon (WS) and Generalized Symmetric Woods-Saxon (GSWS) potentials in order to describe the physical properties of a nucleon, by means of solving Schr\\"odinger equation for the two potentials. The additional term squeezes the WS potential well, which leads an upward shift in the spectrum, resulting in a more realistic picture. The resulting GSWS potential does not merely accommodate extra quasi bound states, but also has modified bound state spectrum. As an application, we apply the formalism to a real problem, an $\\alpha$ particle confined in Bohrium-$270$ nucleus. The thermodynamic functions Helmholtz energy, entropy, internal energy, specific heat of the system are calculated and compared in both wells. The internal energy and the specific heat capacity increase, as a result of upward shift in the spectrum. The shift of the Helmholtz free energy is a direct consequence of the shift of the spectrum. The entropy decreases because of a decrement in the num...

  8. Double-pulse laser ablation sampling: Enhancement of analyte emission by a second laser pulse at 213 nm

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Bruno Yue [Laser Technologies Group, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong (China); Mao, Xianglei [Laser Technologies Group, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Hou, Huaming [Laser Technologies Group, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Ocean University of China, Qingdao (China); Zorba, Vassilia; Russo, Richard E. [Laser Technologies Group, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Cheung, Nai-Ho, E-mail: nhcheung@hkbu.edu.hk [Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong (China)

    2015-08-01

    For the purpose of devising methods for minimally destructive multi-element analysis, we compare the performance of a 266 nm–213 nm double-pulse scheme against that of the single 266 nm pulse scheme. The first laser pulse at 266 nm ablates a mica sample. Ten ns later, the second pulse at 213 nm and 64 mJ cm{sup −2} orthogonally intercepts the gas plume to enhance the analyte signal. Emissions from aluminum, silicon, magnesium and sodium are simultaneously observed. At low 266 nm laser fluence when only sub-ng of sample mass is removed, the signal enhancement by the 213 nm pulse is especially apparent. The minimum detectable amount of aluminum is about 24 fmol; it will be a hundred times higher if the sample is analyzed by the 266 nm pulse alone. The minimum detectable mass for the other analytes is also reduced by about two orders of magnitude when the second pulse at 213 nm is introduced. The spectral and temporal properties of the enhanced signal are consistent with the mechanism of ultra-violet laser excited atomic fluorescence of dense plumes. - Highlights: • We devise a two-laser-pulse scheme to analyze the elemental composition of mica as test samples. • We compare the analytical performance of the single 266 nm pulse scheme against the 266 nm – 213 nm two pulse scheme. • The two pulse scheme improves the absolute LODs of the analytes by about a hundred times. • The spectral and temporal properties of the enhanced signal are consistent with the mechanism.

  9. Aeromonas australiensis sp. nov., isolated from irrigation water.

    Science.gov (United States)

    Aravena-Román, Max; Beaz-Hidalgo, Roxana; Inglis, Timothy J J; Riley, Thomas V; Martínez-Murcia, Antonio J; Chang, Barbara J; Figueras, Maria Jose

    2013-06-01

    A Gram-negative, facultatively anaerobic bacillus, designated strain 266(T), was isolated from an irrigation water system in the south-west of Western Australia. Analysis of the 16S rRNA gene sequence confirmed that strain 266(T) belonged to the genus Aeromonas, with the nearest species being Aeromonas fluvialis (99.6% similarity to the type strain, with 6 nucleotide differences) followed by Aeromonas veronii and Aeromonas allosaccharophila (both 99.5%). Analysis of gyrB and rpoD sequences suggested that strain 266(T) formed a phylogenetic line independent of other species in the genus. This was confirmed using the concatenated sequences of six housekeeping genes (gyrB, rpoD, recA, dnaJ, gyrA and dnaX) that also indicated that A. veronii and A. allosaccharophila were the nearest relatives. DNA-DNA reassociation experiments and phenotypic analysis further supported the conclusion that strain 266(T) represents a novel species, for which the name Aeromonas australiensis sp. nov. is proposed, with type strain 266(T) (=CECT 8023(T) =LMG 26707(T)). [corrected].

  10. Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis

    Energy Technology Data Exchange (ETDEWEB)

    Molle, Virginie; Gulten, Gulcin; Vilchèze, Catherine; Veyron-Churlet, Romain; Zanella-Cléon, Isabelle; Sacchettini, James C.; Jacobs, Jr, William R.; Kremer, Laurent (CNRS-UMR); (Einstein); (TAM)

    2011-08-24

    The remarkable survival ability of Mycobacterium tuberculosis in infected hosts is related to the presence of cell wall-associated mycolic acids. Despite their importance, the mechanisms that modulate expression of these lipids in response to environmental changes are unknown. Here we demonstrate that the enoyl-ACP reductase activity of InhA, an essential enzyme of the mycolic acid biosynthetic pathway and the primary target of the anti-tubercular drug isoniazid, is controlled via phosphorylation. Thr-266 is the unique kinase phosphoacceptor, both in vitro and in vivo. The physiological relevance of Thr-266 phosphorylation was demonstrated using inhA phosphoablative (T266A) or phosphomimetic (T266D/E) mutants. Enoyl reductase activity was severely impaired in the mimetic mutants in vitro, as a consequence of a reduced binding affinity to NADH. Importantly, introduction of inhA{_}T266D/E failed to complement growth and mycolic acid defects of an inhA-thermosensitive Mycobacterium smegmatis strain, in a similar manner to what is observed following isoniazid treatment. This study suggests that phosphorylation of InhA may represent an unusual mechanism that allows M. tuberculosis to regulate its mycolic acid content, thus offering a new approach to future anti-tuberculosis drug development.

  11. Intranasal Delivery of A Novel Amnion Cell Secretome Prevents Neuronal Damage and Preserves Function In A Mouse Multiple Sclerosis Model

    Science.gov (United States)

    Khan, Reas S.; Dine, Kimberly; Bauman, Bailey; Lorentsen, Michael; Lin, Lisa; Brown, Helayna; Hanson, Leah R.; Svitak, Aleta L.; Wessel, Howard; Brown, Larry; Shindler, Kenneth S.

    2017-01-01

    The ability of a novel intranasally delivered amnion cell derived biologic to suppress inflammation, prevent neuronal damage and preserve neurologic function in the experimental autoimmune encephalomyelitis animal model of multiple sclerosis was assessed. Currently, there are no existing optic nerve treatment methods for disease or trauma that result in permanent vision loss. Demyelinating optic nerve inflammation, termed optic neuritis, induces permanent visual dysfunction due to retinal ganglion cell damage in multiple sclerosis and experimental autoimmune encephalomyelitis. ST266, the biological secretome of Amnion-derived Multipotent Progenitor cells, contains multiple anti-inflammatory cytokines and growth factors. Intranasally administered ST266 accumulated in rodent eyes and optic nerves, attenuated visual dysfunction, and prevented retinal ganglion cell loss in experimental optic neuritis, with reduced inflammation and demyelination. Additionally, ST266 reduced retinal ganglion cell death in vitro. Neuroprotective effects involved oxidative stress reduction, SIRT1-mediated mitochondrial function promotion, and pAKT signaling. Intranasal delivery of neuroprotective ST266 is a potential novel, noninvasive therapeutic modality for the eyes, optic nerves and brain. The unique combination of biologic molecules in ST266 provides an innovative approach with broad implications for suppressing inflammation in autoimmune diseases, and for preventing neuronal damage in acute neuronal injury and chronic neurodegenerative diseases such as multiple sclerosis. PMID:28139754

  12. 太阳神的昨天——VIA发展史话(三)

    Institute of Scientific and Technical Information of China (English)

    小白

    2006-01-01

    上期的系列文章中介绍了VIA在进入DDR时代后的坎坷经历,由于VIA推出的P4×266和P4M266侵犯了Intel的经济利益,VIA被Intel以侵权罪名告到了法院。整个P4时代的初期,VIA都被笼罩在这个持久的官司中.在那个经历坎坷的时代里。VIA毅然发布了包括P4×266、P4×333、P4×400在内的多款芯片组,成为了那一时期技术上最为成功的代表产品。

  13. Increased fatty acid synthase as a potential therapeutic target in multiple myeloma

    Institute of Scientific and Technical Information of China (English)

    Wei-qin WANG; Xiao-ying ZHAO; Hai-yan WANG; Yun LIANG

    2008-01-01

    Objective: To determine fatty acid synthase (FAS) expression in human multiple myeloma and verify its potential as a therapeutic target in multiple myeloma. Methods: FAS expression was determined by immunohistochemistry, reverse-transcription polymerase chain reaction (RT-PCR) and immunoblot analysis in bone marrow samples obtained from 27 patients with multiple myeloma (MM patients) and peripheral blood mononuclear cells (PBMCs) obtained from 12 healthy donors. In parallel, additional analyses were performed on 2 human multiple myeloma cell lines, U266 and RPMI8226. U266 cells were treated with cerulenin at various concentrations (5 to 320μg/ml) for 24 h, and metabolic activity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays. Apoptosis was evaluated by dual Annexin V/PI (propidium iodide) labeling and flow cytometry (FCM) in U266 cells treated with 20μg/ml cerulenin for 12 h or 24 h. Results: By immunohistochemistry, we found that 19 of 27 bone marrow samples obtained from MM patients expressed significantly high levels of FAS. Similarly, by RT-PCR, 22 of 27 bone marrow samples obtained from MM patients, U266 and RPMI8226 showed FAS expression, whereas PBMC samples from 12 healthy donors did not express detectable level of FAS. FAS protein expression was confirmed by immunoblot analysis in 16 of 27 bone marrow samples obtained from MM patients, U266 and RPMI8226 cell lines, and no FAS protein expression was detected in PBMC samples from 12 healthy donors. U266 cells were highly sensitive to cerulenin treatment, with a dosage-related effect on metabolic activity, as a measure for cell proliferation. U266 cells treated with20 μg/ml cerulenin for 12 and 24h also showed early sign of apoptosis with 56.9% and 69.3% Annexin V+/PI+ cells, and late apoptotic and necrotic cells with 3.2% and 17.6% Annexin V+/PI+ cells. Conclusion: Increased FAS expression existed in multiple myeloma samples and human myeloma cell lines

  14. Practical Hydrogen Loading of Air Silica Fibres

    DEFF Research Database (Denmark)

    Sørensen, Henrik Rokkjær; Jensen, Jesper Bevensee; Jensen, Jesper Bo Damm;

    2005-01-01

    A method for hydrogen-loading air-silica optical fibres has been developed allowing out-diffusion times comparable to standard step-index fibres. Examples of the first grating written in Ge-doped air-silica fibres using a 266nm UV-laser are shown.......A method for hydrogen-loading air-silica optical fibres has been developed allowing out-diffusion times comparable to standard step-index fibres. Examples of the first grating written in Ge-doped air-silica fibres using a 266nm UV-laser are shown....

  15. Kick to kik. Trabajadores offshore desplazados y ley aplicable a la seguridad social internacional

    Directory of Open Access Journals (Sweden)

    MARINA VARGAS GÓMEZ-URRUTIA

    2015-05-01

    Full Text Available Offshore workers displaced and applicable law to international social security: lex loci laboris, law of residence of the worker or law of the seat of the employer? Responses to light the matter Kik (STJUE c-266/13, 19.3.2015 Trabajadores offshore desplazados y ley aplicable a la seguridad social internacional: ¿lex loci laboris, ley de la residencia del trabajador o ley de la sede del empleador? Respuestas a la luz del asunto Kik (STJUE C-266/13, de 19.3.2015

  16. GETDB: 112201 [GETDB

    Lifescience Database Archive (English)

    Full Text Available 1 1830 Link to cluster table 1830 1 Request - no siganl ubiquitous distal ring of leg, gut ubiquitous (internal) semi lethal - commen...t1:C, comment2:66D11-D12 d1 d2 d3 d4 d5 d6 - - - Show 11...as - Original Comments comment1:C, comment2:66D11-D12 Disc (Image) d1 d2 d3 d4 d5 d6 Disc (number) 6 Embryo ...ing of leg, gut Adult GFP ubiquitous (internal) Lethality semi lethal Also known

  17. Prevalência de parasitoses intestinais na cidade de Eirunepé, Amazonas Prevalence of intestinal parasitosis in the city of Eirunepé, Amazon

    OpenAIRE

    2005-01-01

    Foram analisadas, pelo método de sedimentação espontânea, amostras de fezes de 413 pacientes e encontrada positividade em 266 (64,4%) dos seguintes parasitas: Ascaris lumbricoides (35,6%); Trichuris trichiura (18,6%); Ancilostomídeos(9,9%), Strongyloides stercoralis (1%), Enterobius vermiculares (0,5%), e Entamoeba histolytica (13,3%) e Giardia lamblia (1%).Samples of 413 patient were analyzed and positivity was found in 64.4% (266) of the exams. The intestinal parasites most prevalent were: ...

  18. Grays Harbor and Chehalis River Improvements to Navigation Environmental Studies. Primary Productivity and Organic Carbon Input to Grays Harbor Estuary, Washington.

    Science.gov (United States)

    1981-09-01

    brown fucoid alga Fucus vesiculosus L. The algal associations studied by Pomeroy (1977) exuded from 0 to 30 percent of net carbon (as dissolved...1J79 gC/m2/hr), Fucus distichus ssp. edentatus (0.601 gC/m2/hr), macroscopically evident diatom tufts (0.266 gC/m2/hr), PolysTphonia hendryi var...were: E. intestinalis (1.179 gC/m /hr), Fucus distichus "" 2 ssp. edentatus (0.601 gC/m /hr), macroscopically evident diatom tufts 2 (0.266

  19. Cancer Biomarkers | Division of Cancer Prevention

    Science.gov (United States)

    [[{"fid":"175","view_mode":"default","fields":{"format":"default","field_file_image_alt_text[und][0][value]":"Cancer Biomarkers Research Group Homepage Logo","field_file_image_title_text[und][0][value]":"Cancer Biomarkers Research Group Homepage Logo","field_folder[und]":"15"},"type":"media","attributes":{"alt":"Cancer Biomarkers Research Group Homepage Logo","title":"Cancer Biomarkers Research Group Homepage Logo","height":"266","width":"400","style":"width: 400px; height: 266px;","class":"i | Research to identify, develop and validate biomarkers for early cancer detection and risk assessment.

  20. An experimental paradigm opening the world of superheavy elements

    Science.gov (United States)

    Armbruster, P.; Münzenberg, Gottfried

    2012-07-01

    The history of the discovery of the six elements Z = 107 ∓ 112, bohrium, hassium, meitnerium, darmstadtium, roentgenium, and copernicium goes back to the early 1960s. An experimental method to separate and identify rare nuclear reaction products, the recoil separation, was developed and optimised for beams of fission products at European research reactors. Chemical elements beyond the then first transactinides ( Z = 104), which owe their stability to the internal structure of atomic nuclei, were predicted theoretically. A big brother of the shell-stabilised nucleus 208Pb, a spherical magic nucleus at Z = 114∓126 and N = 184, might reach lifetimes long enough to be detected. In the seventies, hunting superheavy elements (SHE) was on the agenda of nuclear chemistry. Could the Periodic Table of Elements be extended to Z = 120, and is the order of electrons in the atom still following the laws established for lighter elements? In Germany, the heavy ion accelerator (UNILAC) was built by Christoph Schmelzer and his team at GSI, Darmstadt. SHE and UNILAC met the recoil separators in 1968, and SHIP (Separator for Heavy Ion reaction Products) was ready together with the first UNILAC-beams in 1976. Recoil separation is orders of magnitude more sensitive, selective, and faster than earlier methods used to synthesise elements up to seaborgium, Z = 106. The experimental paradigm we introduced opened the world of SHEs. At SHIP we discovered and investigated the elements Z = 107∓112 in the years 1980-2000. Our laboratory was the world champion during this time. Today our experimental method is used worldwide in the search for SHEs, but the leadership went to the Russian laboratory JINR in Dubna, which extended the Periodic Table by 6 more elements to Z = 118, the candidate for the next rare gas.

  1. Synthesis of the heaviest nuclei in cold fusion reactions

    Science.gov (United States)

    Münzenberg, G.; Morita, K.

    2015-12-01

    Cold fusion of heavy ions paved the way to superheavy elements. It was proposed by Yu.Ts. Oganessian more than forty years ago in 1974 [1,2]. First experiments were carried out at JINR Dubna, starting with the reaction 40Ar + 208Pb → 248Fm* where several hundreds to thousand atoms were produced on one day. The large production rate indicating an enhancement of the fusion cross section, especially for the evaporation of two or three neutrons, proved the concept of cold-fusion with the use of the doubly magic nucleus 208Pb as a target. The Dubna experiments were extended to the transactinide region beyond rutherfordium. The breakthrough came with the separation in-flight. Two different approaches were used: kinematic separation with the velocity filter SHIP [3] at GSI Darmstadt, and with the gasfilled separator GARIS [4,5] at RIKEN. With SHIP the concept of cold fusion of massive nuclear systems was convincingly confirmed by the observation of the one-neutron evaporation channel in the production of 247Rf in an irradiation of 208Pb with 50Ti [6] in 1981 which opened the way to the transactinide region. At SHIP the elements bohrium (107) to copernicium (112) were discovered [7]. A new closed shell region around hassium was found. The RIKEN experiments started in 2002. They confirmed the GSI results and in addition improved the data on structure and production of elements hassium to copernicium significantly. The heaviest element ever created in a cold fusion reaction, Z = 113, was observed at GARIS [8,9].

  2. Use of osteoplastic material to guide bone tissue regeneration deffect.

    Science.gov (United States)

    Machavariani, A; Mazmishvili, K; Grdzelidze, T; Menabde, G; Amiranashvili, I

    2011-12-01

    The goal of research was study of restoration processes in jaw-teeth bone defects by application of osteoplastic materials in the experiment. The experiment was performed over 32 white (6-12 month old) rats; the animals were divided into 2 groups; 16 animals were enrolled in the first group; the section was performed in the edge of lower jaw; the lower jaw body was revealed. Under the effect of the dental drilling machine and the # 1 cooling mean by the fissure bohrium (distilled water) the defect of the dimension of 2x2 mm was created; the defect was washed by 0/9% saline to remove the bone sawdust; the wound was sutured tightly, in layers. The second group of the experiment was staffed with 16 animals (main group); the similar bone defect of the size 2 x 2mm was created on the rat's jaw's body. After washing of modeled defect we inserted osteopathic materials PORESORB-TCP crystals with the size of 0,6-1.0 mm the wound was sutured tightly, in layers. After the 3-rd, 15-th, 30-th and 90-th days from the date of operation there was performed X-ray and morphological examination over the animals in the control as well as the main group. The analysis of the examination performed over the experimental materials showed that in the control group in samples taken at 90th day the defects were not completely restored. In the test group in samples taken at 90th day reparative regeneration is confirmed. This is stimulated by the factor that within the main group's animals the defect regeneration process is supported with the osteoplastic material PORESORB-TCP.

  3. Switching behaviour of coupled antiferro- and ferromagnetic systems: exchange bias

    DEFF Research Database (Denmark)

    Lindgård, Per-Anker

    2009-01-01

    in NiO nanoparticles (Kodama and Berkowitz 1999 Phys. Rev. B 59 6321 and Lindgård 2003 J. Magn. Magn. Mater. 266 88)) in a field severely limits the exchange biasing potential. The interface between the different magnets is found to be that originally assumed by Meiklejohn and Bean (1956 Phys. Rev. 102...

  4. 78 FR 32530 - Notice of Final Federal Agency Action on Proposed Highway in Georgia the Northwest I-75/I-575...

    Science.gov (United States)

    2013-05-30

    ... downloaded from the project Web site at http://www.nwcproject.com or at the following local libraries: Central Library, Atlanta-Fulton County Library System, One Margaret Mitchell Square, Atlanta, GA 30303; Central Library, Cobb County Public Library System, 266 Roswell Street, Marietta, GA 30060;...

  5. Training Patterns of Wheelchair Basketball Players in Turkey

    Science.gov (United States)

    Tatar, Yasar

    2008-01-01

    The aim of this study was to analyze technical drills, warm-up and cool-down exercises used by wheelchair basketball players of the Turkish league in relation to training sessions. 33 male wheelchair basketball players participated in the study (mean age 26.6[plus or minus]5,95 years). All players reported that they used warm-up exercises before…

  6. Randomized Controlled Trial of the Focus Parent Training for Toddlers with Autism: 1-Year Outcome

    Science.gov (United States)

    Oosterling, Iris; Visser, Janne; Swinkels, Sophie; Rommelse, Nanda; Donders, Rogier; Woudenberg, Tim; Roos, Sascha; van der Gaag, Rutger Jan; Buitelaar, Jan

    2010-01-01

    This randomized controlled trial compared results obtained after 12 months of nonintensive parent training plus care-as-usual and care-as-usual alone. The training focused on stimulating joint attention and language skills and was based on the intervention described by Drew et al. (Eur Child Adolesc Psychiatr 11:266-272, 2002). Seventy-five…

  7. Drug: D04811 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04811 Mixture, Drug Sulfur and camphor (JP16); Sulfur and camphor (TN) Sulfur [DR:...1] 2 Agents affecting individual organs 26 Epidermides 266 Emollients 2669 Others D04811 Sulfur and camphor (JP16) PubChem: 17398180 ...

  8. Growth in labour productivity of forestry and regional development : a study based on Finnish experience / Seppo Vehkamäki

    Index Scriptorium Estoniae

    Vehkamäki, Seppo

    2003-01-01

    Regionaaltasandil mõjutab metsandussektori töö tootlikkus nii puidutoodete konkurentsivõimet, metsanduse konkurentsivõimelisust tööjõu ja teiste tootmissisendite osas, majanduslikku mitmekesistumist ja arengut kui ka demograafilist ja sotsiaalset arengut. Tabelid. Lisad lk. 265-266

  9. 46th Annual Gun and Missile Systems Conference and Exhibition. Volume 2. Wednesday

    Science.gov (United States)

    2011-09-01

    266-4741 Next Generation Machining & Modeling Technology Presentation NDIA Guns & Missiles 2011 ISO 9001 Certified FS15149 Next...of design, fabrication, acquisition capabilities ISO 9001 Certified FS15149 Next Generation Machining & Modeling Technology • Facts...Management of these elements 3 ISO 9001 Certified FS15149 Next Generation Machining & Modeling Technology Next Generation Machining & Modeling

  10. 76 FR 40118 - Spring 2011 Regulatory Agenda

    Science.gov (United States)

    2011-07-07

    ... for Renewable Fuels Produced Under the Final RFS2 Program From Palm Oil. 10Clean Air Act--Long-Term... Renewable Fuels Produced Under the Final RFS2 Program From Palm Oil Legal Authority: Clean Air Act sec 211(o... No. 266 National Emission 2060-AP52 Standards for Hazardous Air Pollutants From Coal- and...

  11. A Framework for the Integration of E-Learning in Higher Education Institutions in Developing Countries

    Science.gov (United States)

    Kituyi, Geoffrey; Tusubira, Irene

    2013-01-01

    The aim of this research was to design a framework for integrating e-learning in Higher Education Institutions in developing countries. Data were collected from 266 university students and staff of five universities in Uganda using a questionnaire. Data were analyzed using descriptive statistics. The requirements for e-learning integration were…

  12. Effective and versatile software beamformation toolbox

    DEFF Research Database (Denmark)

    Kortbek, Jacob; Nikolov, Svetoslav; Jensen, Jørgen Arendt

    2007-01-01

    and stored in lookup-tables (LUT). Parametric beamforming can also be applied where calculations are done by demand, thus, reducing the storage demand dramatically. On a standard PC with a Pentium 4, 2.66 GHz processor running Linux the toolbox can beamform 100,000 points in lines of various directions in 20...

  13. 8-mJ TEM(00) diode-end-pumped frequency-quadrupled Nd:YAG laser.

    Science.gov (United States)

    Feugnet, G; Pocholle, J P

    1998-01-01

    A frequency-quadrupled Nd:YAG laser pumped by a commercially available high-brightness stack is described. A master oscillator power amplifier configuration was implanted, and the laser delivered energy of 8 mJ at 0.266microm . The laser was air cooled for easy use.

  14. Stability and broad-sense heritability of mineral content in potato: calcium and magnesium

    Science.gov (United States)

    Calcium and magnesium are two minerals with prominent roles in animal and plant metabolism. Advanced potato breeding lines were found to contain between 266 and 944 µg per gram fresh weight of calcium and between 705 1089 µg per gram fresh weight of magnesium. All trials had significant genotype b...

  15. Generic Reference in English, Arabic and Malay: A Cross Linguistic Typology and Comparison

    Science.gov (United States)

    AL-Malki, Eidhah Abdullah; Majid, Norazman Abdul; Omar, Noor Abidah Mohd

    2014-01-01

    According to the Longman Grammar of Spoken and Written English 1999 by Biber et al. (p. 266) generic article uses are more than twice as common in academic English than in conversation or fiction. This is an area that English for Academic Purpose (EPA) textbooks and teachers would need to target more than general English teaching. This paper is…

  16. Fusing Multiple Sensor Modalities for Complex Physiological State Monitoring

    Science.gov (United States)

    2012-12-01

    Canadian Journal of Experimental Psychology December 2000, 54 (4), 266. Academic Search Premier, EBSCOhost (accessed June 18, 2012). 20. Simon, M... EBSCOhost (accessed June 18, 2012). 30. Hugemann, W. Driver Reaction Times in Road Traffic, 06–07 Sept. 2002. (From EVU 2002 in Slovenija, Portoroz

  17. 41 CFR 101-26.602-4 - Procurement of coal.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Procurement of coal. 101... PROGRAM 26.6-Procurement Sources Other Than GSA § 101-26.602-4 Procurement of coal. (a) Federal agencies desiring to participate in the Defense Fuel Supply Center coal contracting program for carload...

  18. Dicty_cDB: SLG236 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 8 clone RP11-266D22, WORK... 46 0.30 4 ( FJ445111 ) Human rhinovirus 1 strain ATC...C VR-1559, complete ... 48 0.45 1 ( AY436674 ) Human rhinovirus 1A polymerase (3D) mRNA, partial... 48 0.45

  19. Domain Modeling: NP_037512.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_037512.3 chr19 Aart, a six finger zinc finger designed to recognize ANN triplets... c2i13b_ chr19/NP_037512.3/NP_037512.3_holo_250-425.pdb blast 257Y,259K,261F,262S,264D,265S,266S,268E,270H,2

  20. Proceedings of the Annual Military Librarians’ Workshop (21st): Resource Sharing, 27-29 September 1977

    Science.gov (United States)

    1977-09-29

    Library Fort Devens, MA 01433 Betty H. Fogler AV: 266-2031 Reference Librarian (Govt Docs Chief) US Air Force Academy Library SEleanor A. Driscoll USAF...Carlisle Barracks, PA 17013 Scott AFE, IL 62225 AV- 242-4442 AV: 638-3228SA 6George Vrooman Dodie C. Thomas Lihrarian Branc Offie, LndonBo 3 DevLopmerint

  1. Triticum Mosaic Virus: A Distinct Member of the Family Potyviridae with an Unusually Long Leader Sequence

    Science.gov (United States)

    The complete genome sequence of Triticum mosaic virus (TriMV), a member in the family Potyviridae, has been determined to be 10,266 nucleotides excluding the 3’-polyadenylated tail. The genome encodes a large polyprotein of 3,112 amino acids with the ‘hall-mark proteins’ of potyviruses including a s...

  2. Drug: D04810 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 99 Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 23 Digestive organ agents... 235 Purgatives, clysters 2359 Others D04810 Potash soap (JP16) 26 Epidermides 266 Emollients 2662 Alkaline agents

  3. Naturally conceived twins with monochorionic placentation have the highest risk of fetal loss

    DEFF Research Database (Denmark)

    Sperling, Lene; Kiil, C; Larsen, L U;

    2006-01-01

    naturally and 266 (54%) by assisted reproduction (AR). Outcome data for 945 liveborn babies were obtained. The spontaneous miscarriage rate before 24 weeks' gestation was 10.9% (7/64) among naturally conceived MC compared to 3.0% (5/165) for naturally conceived DC twins (P

  4. Gclust Server: 86868 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 86868 Mtu_Rv3045=adhC Cluster Sequences Related Sequences(266) 346 PROBABLE NADP-DE...PENDENT ALCOHOL DEHYDROGENASE ADHC 1 1.00e-31 0.0 0.0 0.0 0.0 3.23 0.0 Show 86868 Cluster ID 86868 Sequence

  5. IR-REMPI spectroscopy for thermometry of C-60

    NARCIS (Netherlands)

    van Heijnsbergen, D.; von Helden, G.; Sartakov, B.; Meijer, G.

    2000-01-01

    Gas-phase C-60 molecules are excited with a 30 ps 266 nm Nd:YAG laser, followed by a train of high-power infrared (IR) sub-picosecond pulses from a free electron laser (FEL), which resonantly heats the molecules up to internal energies at which they efficiently undergo delayed ionization. By tuning

  6. Drug: D01168 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01168 Drug Potassium hydroxide (JP16/NF); Potassium hydroxide (TN) KOH 55.9664 56....Glycerin and potash solution [DR:D04809] Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affect...ing individual organs 26 Epidermides 266 Emollients 2662 Alkaline agents D01168 Potassium hydr

  7. The Effect of Morphaction on the Kinetics of Indol-3yl-Acetic Acid-2-14C Transport in Zea Mays L. Coleoptile Segments

    DEFF Research Database (Denmark)

    Naqvi, S. M.

    1972-01-01

    This paper elucidates the effects of chloroflurenol (morphactin, IT 3456) treatment on the kinetics of 14C-IAA transport through Zea mays L. (cv. Orla-266) coleoptile segments. Maximum inhibition of transport was achieved when chloroflurenol remained in contact with the tissue segments for at least...

  8. PCR specific for Actinobacillus pleuropneumoniae serotype 3

    DEFF Research Database (Denmark)

    Zhou, L.; Jones, S.C.P.; Angen, Øystein

    2008-01-01

    , but the method has liminations, for example, cross-reactions between serotypes 3, 6, and 8. This study describes the development of a serotype 3-specific PCR, based on the capsule locus, which can be used in a multiplex format with the organism's specific gene apxIV. The PCR test was evaluated on 266 strains...

  9. Understanding Discrepancy in Perceptions of Values: Individuals with Mild to Moderate Dementia and Their Family Caregivers

    Science.gov (United States)

    Reamy, Allison M.; Kim, Kyungmin; Zarit, Steven H.; Whitlatch, Carol J.

    2011-01-01

    Purpose of the Study: We explore discrepancies in perceptions of values and care preferences between individuals with dementia (IWDs) and their family caregivers. Design and Methods: We interviewed 266 dyads consisting of an individual with mild to moderate dementia and his or her family caregiver to determine IWDs' beliefs for 5 values related to…

  10. Brief Report: Reducing Earthquake-Related Fears in Victim and Nonvictim Children

    Science.gov (United States)

    Karairmak, Ozlem; Aydin, GuL

    2008-01-01

    In this study, the authors investigated the fears of earthquake victim and nonvictim elementary school students and the effectiveness of an activity-based cognitive fear reduction (ABCF) procedure developed by the authors. To measure fear, the authors collected data from 266 participants using a modified version of the Fear Survey Schedule for…

  11. Adolescents' Social Goals, Beliefs about the Causes of Social Success, and Satisfaction in Peer Relations.

    Science.gov (United States)

    Jarvinen, Denis W.; Nicholls, John G.

    1996-01-01

    Examined the social goals and beliefs involved in adolescent peer relationships among 266 ninth-grade students. Factor analysis of questionnaire responses identified relevant goals (intimacy, nurturance, dominance, leadership, popularity, and avoidance) and beliefs (sincerity, status, responsibility, caring, entertaining, and toughness) concerning…

  12. 40 CFR 271.21 - Procedures for revision of State programs.

    Science.gov (United States)

    2010-07-01

    ... amendments to 40 CFR parts 124, 270, 260-266, or 268 and any self-implementing statutory provisions (i.e... the documentation described in paragraph (b) of this section to revise its program. (f) A State must... Monitoring Activities, Methods Innovation Rule July 14, 2005 70 FR 34538, June 14, 2005 Process Vent...

  13. Measurement of the dispersion law for hydrophobic silica aerogel SP-25

    Energy Technology Data Exchange (ETDEWEB)

    Villoro, M.F.; Plascencia, J.C.; Nunez, R.; Menchaca-Rocha, A. E-mail: amen@servidor.unam.mx; Hernandez, J.M.; Camarillo, E.; Buenerd, M

    2002-03-21

    Optical properties of hydrophobic silica aerogel SP-25 have been measured. These include: a seven point dispersion law n({lambda}=266.2-514.5 nm), absorbance, luminescence and other physical properties. The effect of chromatic dispersion on velocity resolution for an aerogel-based RICH counter was estimated.

  14. Data of evolutionary structure change: 1OZFB-1UPCF [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1OZFB-1UPCF 1OZF 1UPC B F YPVRQWAHGADLVVSQLEAQGVRQVFGIPGAKIDKVFDS... 263 ASP CA 266 1UPC F 1UPC... 1UPC F 1UPCF MET CA 302 1UPC F 1UPC...CA 345 LEU CA 430 VAL CA 464 HIS CA 467 1UPC

  15. AcEST: BP920294 [AcEST

    Lifescience Database Archive (English)

    Full Text Available +K Sbjct: 214 LK 215 >tr|Q72RN2|Q72RN2_LEPIC Motility protein B OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar copen...hageni GN=LIC_11713 PE=4 SV=1 Length = 266 Score = 53.1 bits (126), Expect = 7e-06

  16. Reference: ARE1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ARE1 Rushmore TH, Morton MR, Pickett CB The antioxidant responsive element. Activation by oxidative stre...ss and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266:11632-11639 (1991) PubMed: 1646813; ...

  17. A population-based survey to assess troublesome symptoms in gastroesophageal reflux disease

    DEFF Research Database (Denmark)

    Reimer, Christina; Bytzer, Peter

    2009-01-01

    on the classification of troublesome symptoms based on frequency and severity and self-reported troublesome symptoms was poor to fair. Using 4 as the cut-off point on the VAS showed the best agreement (kappa = 0.35). Of the 482 symptomatic respondents, 266 (55%) had troublesome symptoms based on frequency and severity...

  18. 40 CFR 261.39 - Conditional Exclusion for Used, Broken Cathode Ray Tubes (CRTs) and Processed CRT Glass...

    Science.gov (United States)

    2010-07-01

    ... complete until any such claim is resolved in accordance with 40 CFR 260.2. (v) The export of CRTs is... CFR part 266, subpart C instead of the requirements of this section. ... Cathode Ray Tubes (CRTs) and Processed CRT Glass Undergoing Recycling. 261.39 Section 261.39 Protection...

  19. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

    DEFF Research Database (Denmark)

    Thorgeirsson, Thorgeir E; Gudbjartsson, Daniel F; Surakka, Ida;

    2010-01-01

    Smoking is a common risk factor for many diseases. We conducted genome-wide association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers (n = 31,266) and smoking initiation (n = 46,481) using samples from the ENGAGE Consortium. In a second stage, we tested selected SNPs ...

  20. Improving Awareness of Health Hazards Associated with Air Pollution in Primary School Children: Design and Test of Didactic Tools

    Science.gov (United States)

    Carducci, Annalaura; Casini, Beatrice; Donzelli, Gabriele; Verani, Marco; Bruni, Beatrice; Ceretti, Elisabetta; Zani, Claudia; Carraro, Elisabetta; Bonetta, Sara; Bagordo, Francesco; Grassi, Tiziana; Villarini, Milena; Bonizzoni, Silvia; Zagni, Licia; Gelatti, Umberto

    2016-01-01

    One of the objectives of the MAPEC-Life project is raising children's awareness on air quality and its health effects. To achieve this goal, we designed didactic tools for primary school students, including leaflets with more information for teachers, a cartoon, and three educational videogames. The tools were then tested with 266 children who…

  1. HYDROGENATION OF 4-OXOISOPHORONE IN SUPERCRITICAL CO2 MEDIUM OVER ALUMINA SUPPORTED PALLADIUM CATALYST

    Science.gov (United States)

    Ketoisophorone or 4-oxoisophorone (2,6,6-trimethyl-cyclohex-2-ene-1,4-dione) is a cyclic enedione of tremendous industrial importance due to its use as a key intermediate in the synthesis of various carotenoids and flavoring agents. The catalytic hydrogenation and enzymatic reduc...

  2. 77 FR 19455 - Regulations Implementing the Byrd Amendments to the Black Lung Benefits Act: Determining Coal...

    Science.gov (United States)

    2012-03-30

    .... USI Film Prod., 511 U.S. 244, 266-270 (1994). Because the ACA expressly requires retroactive... they merely provide historical information and are not relevant to the adjudication of any current... editorial changes made to update the regulation and eliminate information only of historical interest....

  3. Physical characterization of Galactic O-type stars targeted by the IACOB and OWN surveys

    CERN Document Server

    Holgado, G; Barbá, R H

    2016-01-01

    We present first results from the quantitative spectroscopic analysis of 266 Galactic O-type stars targeted by the IACOB and OWN surveys (implying the largest sample of stars of this type analyzed homogeneously). We also evaluate what is the present situation regarding available information about distances, as provided by the Hipparcos and Gaia missions.

  4. Interpersonal Communication Barriers Identified by Business Communication Students.

    Science.gov (United States)

    Golen, Steven

    1985-01-01

    Presents a study conducted to determine which barriers to effective communication are perceived as most serious by business communication students and to test for differences in the seriousness of the communication barriers based on various student characteristics. The sample consisted of 266 student registered in 10 sections of business…

  5. Serum cholesterol decline and depression in the postpartum period

    NARCIS (Netherlands)

    Dam, van R.M.; Schuit, A.J.; Schouten, E.G.; Vader, H.L.; Pop, V.J.M.

    1999-01-01

    We examined the relation between total serum cholesterol decline and depression in the postpartum period in a prospective study of 266 Dutch women, who were followed until 34 weeks after delivery. The decline in serum cholesterol between week 32 of pregnancy and week 10 postpartum was similar for wo

  6. Catalytic Amination of Alcohols, Aldehydes, and Ketones

    Science.gov (United States)

    Klyuev, M. V.; Khidekel', M. L.

    1980-01-01

    Data on the catalytic amination of alcohols and carbonyl compounds are examined, the catalysts for these processes are described, and the problems of their effectiveness, selectivity, and stability are discussed. The possible mechanisms of the reactions indicated are presented. The bibliography includes 266 references.

  7. 76 FR 28191 - Petition for Rulemaking Submitted by Mr. Erik Erb and 91 Cosigners

    Science.gov (United States)

    2011-05-16

    ... rulemaking (PRM) submitted by Erik Erb, the petitioner, and 91 cosigners, in the planned ``Quality Control..., (75 FR 71368), the NRC published a Notice of Receipt of a PRM filed on August 17, 2010, by Erik Erb... NRC received five public comments. The NRC determined that the issues raised in PRM-26-6...

  8. Work-Related Well-Being of Educators in a District of the North-West Province

    Science.gov (United States)

    Jackson, Leon; Rothmann, Sebastiaan

    2005-01-01

    The objectives of this article were to assess the relationship between burnout, health, job demands and job resources in a sample of educators. A cross-sectional survey design was used. Stratified random samples (N = 266) were taken of educators in an area of the North-West Province. The Maslach Burnout Inventory-General Survey, the Health…

  9. Mental Health among College Students: Do Those Who Need Services Know about and Use Them?

    Science.gov (United States)

    Yorgason, Jeremy B.; Linville, Deanna; Zitzman, Bryan

    2008-01-01

    Objective: The objective of this study was to examine connections between university students' mental health and their knowledge and use of campus mental health services. Participants and Methods: In March 2001, a sample of undergraduate students (N = 266) completed a Web-based questionnaire, providing information related to their mental health,…

  10. An Evaluation of the Brief Symptom Inventory-18 Using Item Response Theory : Which Items Are Most Strongly Related to Psychological Distress?

    NARCIS (Netherlands)

    Meijer, Rob R.; de Vries, Rivka M.; van Bruggen, Vincent

    2011-01-01

    The psychometric structure of the Brief Symptom Inventory-18 (BSI-18; Derogatis, 2001) was investigated using Mokken scaling and parametric item response theory. Data of 487 outpatients, 266 students, and 207 prisoners were analyzed. Results of the Mokken analysis indicated that the BSI-18 formed a

  11. An evaluation of the Brief Symptom Inventory-18 using item response theory: which items are most strongly related to psychological distress?

    NARCIS (Netherlands)

    Meijer, Rob R.; Vries, de Rivka M.; Bruggen, van Vincent

    2011-01-01

    The psychometric structure of the Brief Symptom Inventory–18 (BSI-18; Derogatis, 2001) was investigated using Mokken scaling and parametric item response theory. Data of 487 outpatients, 266 students, and 207 prisoners were analyzed. Results of the Mokken analysis indicated that the BSI-18 formed a

  12. An Evaluation of the Brief Symptom Inventory-18 Using Item Response Theory: Which Items Are Most Strongly Related to Psychological Distress?

    Science.gov (United States)

    Meijer, Rob R.; de Vries, Rivka M.; van Bruggen, Vincent

    2011-01-01

    The psychometric structure of the Brief Symptom Inventory-18 (BSI-18; Derogatis, 2001) was investigated using Mokken scaling and parametric item response theory. Data of 487 outpatients, 266 students, and 207 prisoners were analyzed. Results of the Mokken analysis indicated that the BSI-18 formed a strong Mokken scale for outpatients and…

  13. BATTLE (Biomarker-based Approaches of Targeted Therapy for Lung Cancer Elimination)

    Science.gov (United States)

    2011-04-01

    evaluated biopsies are banked in the Biomarker Core, and they represent 588 ti ssue blocks from 266 cases (2.2 block/case; range 1-4) and 3,965...complex  (DakoCytomation)  and  developed  with  3,  39-diaminobenzidine.  The  sections  were  then  rinsed  in  distilled  water ,  counterstained

  14. Dos tesis convertidas en un libro

    OpenAIRE

    Renán Vega Cantor

    2013-01-01

    Esclavos, negros libres y bogas en la literatura del siglo XIX. María Camila Nieto Villamizar y María Riaño Pradilla. Universidad de los Andes, Facultad de Ciencias Sociales, Departamento de Historia, Centro de Estudios Socioculturales e Internacionales (Ceso), Bogotá, 2011. 266 págs., il.

  15. Plankton biodiversity of Dharamtar creek adjoining Mumbai harbour

    Digital Repository Service at National Institute of Oceanography (India)

    Tiwari, L; Nair, V.R.

    , 6 dinoflagellates and 6 other algae. Variation in phytoplankton cell count was enormous (17-5980 x 10 sup(3) l sup(-1)) with an average cell count of 266 x 10 sup(3) l sup(-1). The phytoplankton community was dominated by diatoms (97.6%) followed...

  16. Congressional Oversight of Intelligence: Current Structure and Alternatives

    Science.gov (United States)

    2012-03-14

    JCAE, this joint panel was a short-term, periodic addition to Congress, set up by the Gramm-Rudman-Hollings Act of 1985 ( GRH ). The panel could come...provision apparently was never activated and was not included in the 1987 revision of GRH . 27 Green and Rosenthal, Government of the Atom, p. 266

  17. Education for Sustainability: A Case Study of Preservice Primary Teachers' Knowledge and Efficacy

    Science.gov (United States)

    Effeney, Gerard; Davis, Julie

    2013-01-01

    This study investigated the relationships between knowledge and efficacy for teaching sustainability in a sample of 266 pre-service primary teachers at a large, metropolitan university in Australia. A survey gathered information about the participant's attitudes and self-efficacy for education for sustainability, along with their perceived and…

  18. Estudios sobre disponibilidad léxica en el español de Galicia [RESEÑA

    OpenAIRE

    Jiménez-Berrio, F. (Felipe)

    2013-01-01

    Reseña de López Meirama, Belén, ed. Estudios sobre disponibilidad léxica en el español de Galicia. Colección Lalia. Series Maior, 24. Santiago de Compostela: Servizo de Publicacións e Intercambio Científico Universidade, 2011. 266 pp. (ISBN: 978-84-9887-748-7)

  19. Bio-ag reutilization of distiller’s dried grains with solubles (DDGS) as a substrate for black soldier fly larvae, Hermetia illucens, along with poultry by-product meal and soybean meal, as total replacement of fish meal in

    Science.gov (United States)

    A feeding trial was conducted in a closed system with Nile tilapia, Oreochromis niloticus, juveniles (mean initial weight, 2.66 g) to examine total replacement of menhaden fish meal (FM) with distiller’s dried grains with solubles (DDGS), which had been used as substrate for the production of black ...

  20. "美文"一篇,遐思无限

    Institute of Scientific and Technical Information of China (English)

    李海梅

    2010-01-01

    @@ Reading Expression Words:266 Time: 12 minutes As the pace of life continues to increase, we are fast losing the art of relaxation. Once you are in the habit of rushing through life, being on the go from morning till night, it is hard to slow down. But relaxation is essential for a healthy mind and body.

  1. 40 CFR 63.4551 - How do I demonstrate initial compliance with the emission limitations?

    Science.gov (United States)

    2010-07-01

    ... initial compliance demonstration for each general use, TPO, automotive lamp, and assembled on-road vehicle... Products” (incorporated by reference, see § 63.14), information from the supplier or manufacturer of the... facility that is regulated as a TSDF under 40 CFR part 262, 264, 265, or 266. The TSDF may be either...

  2. Does Self-Image Matter? Client's Self-Image, Behaviour and Evaluation of a Career Counselling Session: An Exploratory Study

    Science.gov (United States)

    Schedin, Gunnar; Armelius, Kerstin

    2008-01-01

    This exploratory study addresses differences in self-image as a client characteristic in career counselling by using the Structural Analysis of Social Behaviour (Benjamin, L., "Journal of Consulting and Clinical Psychology," 64(6), 1203-1212, 1996; Benjamin, L., "Journal of Personality Assessment," 66(2), 248-266, 1996) and an adaptation…

  3. Individual Differences and Learning Performance in Computer-based Training

    Science.gov (United States)

    2011-02-01

    Navigation in hypermedia learning systems: experts vs. novices. Computers in Human Behavior , 22, 251–266. Chi, M. T. H., Glaser, R., & Rees, E...communication technologies on performance in a Web-based learning program. Computers in Human Behavior , 22(6), 962-970. Shivpuri, S., Schmitt, N., Oswald

  4. Excessive Progression in Weekly Running Distance and Risk of Running-related Injuries

    DEFF Research Database (Denmark)

    Nielsen, R.O.; Parner, Erik Thorlund; Nohr, Ellen Aagaard

    2014-01-01

    trochanteric bursitis, injury to the tensor fascia latae, and patellar tendinopathy) existed in those who progressed their weekly running distance by more than 30% compared with those who progressed less than 10% (hazard ratio = 1.59; 95% confidence interval: 0.96, 2.66; P = .07). Conclusion Novice runners who...

  5. Classroom assessment in the eyes of Chinese primary mathematics teachers: A review of teacher-written papers

    NARCIS (Netherlands)

    Zhao, X.; Van den Heuvel-Panhuizen, M.; Veldhuis, M.

    2017-01-01

    In this paper we report on a review of papers written by teachers aimed at knowing more about teachers’ perceptions of the current situation of classroom assessment in primary mathematics education in China. The review is based on 266 papers included in the China National Knowledge Infrastructure da

  6. Nanosecond pulsed laser deposition of TiO{sub 2}: nanostructure and morphology of deposits and plasma diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Sanz, Mikel; Walczak, Malgorzata; Oujja, Mohamed; Cuesta, Angel [Instituto de Quimica Fisica Rocasolano, CSIC, Serrano 119, 28006 Madrid (Spain); Castillejo, Marta, E-mail: marta.castillejo@iqfr.csic.e [Instituto de Quimica Fisica Rocasolano, CSIC, Serrano 119, 28006 Madrid (Spain)

    2009-10-30

    Nanostructured TiO{sub 2} films on Si (100) substrates have been grown by nanosecond pulsed laser deposition at the wavelengths of 266, 355 and 532 nm using a Q-switched Nd:YAG laser and TiO{sub 2} sintered rutile targets. The effect of laser irradiation wavelength, the temperature of the substrate and the presence of O{sub 2} as background gas on the crystallinity and surface structure of deposits were determined, together with the composition, expansion dynamics and thermodynamic parameters of the ablation plume. Deposits were analyzed by X-ray photoelectron spectroscopy, X-ray diffraction, environmental scanning electron microscopy and atomic force microscopy, while in situ monitoring of the plume was carried out and characterized with spectral, temporal and spatial resolution by optical emission spectroscopy. Stoichiometric, crystalline deposits, with nanostructured morphology were obtained at substrate temperatures above 600 {sup o}C. Microscopic particulates were found overimposed on the nanostructured films but their size and density were significantly reduced by operating at short wavelength (266 nm) and upon addition of a low pressure of oxygen (0.05 Pa). The dominant crystalline phase is rutile at 355 and 532 nm. At the short irradiation wavelength, 266 nm, the preferred phase in the presence of oxygen is rutile, while anatase is preferably observed under vacuum. The narrowest size distribution and smallest nanoparticle diameters, of around 25 nm, were found by deposition at 266 nm under 0.05 Pa of oxygen.

  7. Developing the Evaluation Scale to Determine the Impact of Body Language in an Argument: Reliability & Validity Analysis

    Science.gov (United States)

    Karadag, Engin; Caliskan, Nihat; Yesil, Rustu

    2008-01-01

    In this research, it is aimed to develop a scale to observe the body language which is used during an argument. A sample group of 266 teacher candidates study at the departments of Class, Turkish or Social Sciences at the Faculty of Education was used in this study. A logical and statistical approach was pursued during the development of scale. An…

  8. Medical Entomology Studies - XV. A Revision of the Subgenus Paraedes of the Genus Aedes (Diptera: Culicidae)

    Science.gov (United States)

    1981-01-01

    Med. Res. 10: 430-75. Diptera Nematocera from the Federated Malay States museums. J. Fed. Malay States Mus. 14: l-139. Philippine nematocerous...Culicidae. p. 266-343. In M. D. Delfinado and D. E. Hardy, Ed. A catalog of the Diptera of the Oriental region. Volume I. Suborder Nematocera . Univ

  9. Medical Entomology Studies - XVI. A Review of the Species of Subgenus Verrallina, Genus Aedes, from Sri Lanka and a Revised Description of the Subgenus (Diptera: Culicidae)

    Science.gov (United States)

    1984-01-01

    351-401. Diptera Nematocera from the Federated Malay States Museums. J. Fed. Malay States Mus. 14: 1-139, 2 pls. Diptera, Fam. Culicidae. In P...266-343. In M. D. Delfinado and D. E. Hardy, Ed. A catalog of the Diptera of the Oriental region. Volume I. Suborder Nematocera . Univ. Press Hawaii

  10. An Annotated Bibliography of the Mosquitoes and Mosquito-Borne Diseases of Guam (Diptera: Culicidae)

    Science.gov (United States)

    1976-01-01

    Nematocera . University Press of Hawaii, Honolulu, Hawaii. 618 pp. Family Culicidae; see A. Stone and M.D. Delfinado, 1973. 359 Edgren, D.C., V.S...Culicidae, in Delfinado, M.D. and D.E. Hardy (Eds.), A Catalog of the Diptera of the Oriental Region, Vol. 1: Nematocera , pp. 266-343. University Press

  11. Scholeksters en hun voedsel in de Waddenzee

    NARCIS (Netherlands)

    Rappoldt, C.; Ens, B.J.; Bult, T.P.; Dijkman, E.M.

    2003-01-01

    Dit rapport bevat een analyse van de voedselsituatie van scholeksters gedurende de negentiger jarenin de Waddenzee. Het aantal overwinterende scholeksters is afgenomen van 266 000 in de jaren tachtig tot 170 000 aan het eind van de jaren negentig. De oorzaak is een tekort aan voedsel dat in de eerst

  12. What Do Young Children Dream about?

    Science.gov (United States)

    Honig, Alice Sterling; Nealis, Arlene L.

    2012-01-01

    Young children's dreams can be a way for teachers and caregivers to share with children and an opportunity for children to describe and even draw dreams. In two different preschool settings, in two different geographical locales, 94 children, aged 3-5 years, shared 266 dreams with a trusted, familiar teacher. Dreams were coded anonymously. The…

  13. Water Remedial Investigation Report, Version 3.3. Volume 2

    Science.gov (United States)

    1989-07-01

    Farenheit OXAT oxathiane 0 • OX/DITH Combined oxathiane and dithiane PCE tetrachloroethylene PI plasticity index PID photoionization detector S PMO...TIME 10:24 ’ UNKSIS 91515 26.6 ,I ,2-TRICHLOROETHANE UNKS31 91531 39.1 1,1,2,2-TETRACHLOROETHANE UNK565 91565 451 CAPROLACTAM UNK642 91642 1340 UNK

  14. GETDB: 103768 [GETDB

    Lifescience Database Archive (English)

    Full Text Available e of Genetics. TM3 Ser Link to clone table - 1 1821 Link to cluster table 1821 1 Request - cns + pns subset - sg - lethal - comment...1:A, comment2:66B10 - - - - Show 103768 DGRC Number 103768...arval X-gal sg Adult GFP - Lethality lethal Also known as - Original Comments comment1:A, comment

  15. 76 FR 29770 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-05-23

    ... for Scientific Review Special Emphasis Panel; PAR10-266: Program Project: NFKB Cell Signal Theory and... HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings... Committee: Center for Scientific Review Special Emphasis Panel; Member Conflict: AIDS/HIV. Date: June...

  16. Disease: H00351 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available acteria that causes human respiratory infections. Repeated or prolonged exposure to Cp. pneumoniae is associated with asthma...tic bronchitis and asthma, and chronic infection can contribute to the development of adult-onset asthma...ov R Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma. JAMA 266:225-30 (1991) ...

  17. Apoptotic effects of non-edible parts of Punica granatum on human multiple myeloma cells.

    Science.gov (United States)

    Kiraz, Yağmur; Neergheen-Bhujun, Vidushi S; Rummun, Nawraj; Baran, Yusuf

    2016-02-01

    Multiple myeloma is of great concern since existing therapies are unable to cure this clinical condition. Alternative therapeutic approaches are mandatory, and the use of plant extracts is considered interesting. Punica granatum and its derived products were suggested as potential anticancer agents due to the presence of bioactive compounds. Thus, polypenolic-rich extracts of the non-edible parts of P. granatum were investigated for their antiproliferative and apoptotic effects on U266 multiple myeloma cells. We demonstrated that there were dose-dependent decreases in the proliferation of U266 cells in response to P. granatum extracts. Also, exposure to the extracts triggered apoptosis with significant increases in loss of mitochondrial membrane potential in U266 cells exposed to the leaves and stem extracts, while the flower extract resulted in slight increases in loss of MMP. These results were confirmed by Annexin-V analysis. These results documented the cytotoxic and apoptotic effects of P. granatum extracts on human U266 multiple myeloma cells via disruption of mitochondrial membrane potential and increasing cell cycle arrest. The data suggest that the extracts can be envisaged in cancer chemoprevention and call for further exploration into the potential application of these plant parts.

  18. Review and Synopsis of Natural and Human Controls on Fluvial Channel Processes in the Arid West

    Science.gov (United States)

    2007-09-01

    and other wet saline and alkaline soils: Problems identifying aquic conditions and hydric soils. In Aquic Conditions and Hydric Soils: The Problem...of-the-art of hydrology and hydrogeology in the arid and semi-arid areas of Africa. p. 255–266. Proceedings of the Sahel Forum 1989. Ouagadougou

  19. 31 CFR 7.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... Finance: Treasury Office of the Secretary of the Treasury EMPLOYEE INVENTIONS § 7.1 Purpose. Provisions defining the right, title, and interest of the Government in and to an invention made by a Government... forth in Executive Order 10096, 15 FR 389, as amended (35 U.S.C. 266 note). Further definition of...

  20. Proceedings of the Air Force Geophysics Laboratory Workshop on the Earth’s Radiation Belts: 26-27 January 1981.

    Science.gov (United States)

    1981-10-21

    P., Balsiger, H., Haerendel, G., and Rosenbaum, H. (1978) Plasma composition experiment on ISEE-A, IEEE Transactions on Geoscience Electronics, GE-16...Rosenbauer, H. (1978) Plasma composition experiment on ISEE-A, IEEE Trans. Geosci. Elect. 16:266. 15. Harris, K.K., Sharp, G.W., and Chappell, C.R. (1970

  1. A Role for the NFkB/Rel Transcription Factors in Human Breast Cancer

    Science.gov (United States)

    1996-07-01

    transcription through NF-kB binding sites ( Galang et al., 1996). We have previously found that a breast cancer cell line exhibited constitutive...Futreal, P., Q. Liu, D. Shattuck-Eidens et al. (1994). BRCA1 mutations in primary breast and ovarian carcinomas. Science 266: 120-122. Galang , C., J

  2. The influence of product and oral characteristics on swallowing

    NARCIS (Netherlands)

    Engelen, L; Fontijn-Tekamp, A; van der Bilt, A

    2005-01-01

    The urge to swallow food could be triggered by a threshold level in both food particle size and lubrication of the food bolus. Thus, both oral physiology and product characteristics may influence the swallowing threshold. We quantified the swallowing threshold in a group of 266 healthy adult subject

  3. Dicty_cDB: Contig-U09415-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available lectin mRNA, co... 35 3.0 CU928167_266( CU928167 |pid:none) Kluyveromyces thermotol... 2.3 BT023457_1( BT023457 |pid:none) Arabidopsis thaliana At1g67440 gen... 35 2.3 AY509881_1( AY509881 |pid:none) Equus caballus P-se

  4. 75 FR 14206 - FPL Energy Point Beach, LLC; Point Beach Nuclear Plant, Units 1 and 2; Environmental Assessment...

    Science.gov (United States)

    2010-03-24

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION [Docket Nos. 50-266 And 50-301; NRC-2010-0123 FPL Energy Point Beach, LLC; Point Beach Nuclear Plant, Units 1 and 2; Environmental Assessment and Finding of No Significant Impact The U.S....

  5. Modulation of the acute phase response in feedlot steers supplemented with Saccharomyces cerevisiae

    Science.gov (United States)

    This study was designed to determine the effect of supplementing feedlot steers with Saccharomyces cerevisiae CNCM I-1079 (SC) on the acute phase response to a lipopolysaccharide (LPS) challenge. Steers (n = 18; 266 ± 4 kilograms body weight) were separated into three treatment groups (n = 6/treatm...

  6. Dicty_cDB: AFL124 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available pph30f12, 3' end, single read. 266 1e-96 2 CN206669 |CN206669.1 Tor7097 Gametophy... 66 1e-06 1 CN206834 |CN206834.1 Tor7258 Gametophyte rehydration Library Tortula ruralis cDNA, mRNA sequence

  7. Ühetaoline mõistekasutus karistusõiguses. Riigikohtu otsus 3-1-1-40-12 / Jaan Sootak

    Index Scriptorium Estoniae

    Sootak, Jaan, 1948-

    2012-01-01

    Karistusseadustiku § 266 (omavoliline sissetung) koosseisutunnuste – valdus, võõras asi, sissetungimise ebaseaduslikkus – käsitlusest Riigikohtu otsuses 3-1-1-40-12. Süülise hädaseisundi olemusest ja selle õiguslikest tagajärgedest

  8. Drug: D00604 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 4 266.5548 D00604.gif Antihypertensive Therapeutic category: 2149 ATC code: C02AC01 N02CX02 S01EA04 alpha2-a...Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 21 Cardiovascular agents 214 Antihypertensiv

  9. Domain Modeling: NP_066574.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_066574.2 chr2 CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA c1meyf_ chr2/NP_066574....2/NP_066574.2_holo_254-335.pdb blast 255K,259C,261E,262C,263G,264K,265A,266F,267F,268D

  10. Long-term prognosis of patients with local recurrence after conservative surgery and radiotherapy for early breast cancer

    NARCIS (Netherlands)

    A.C. Voogd (Adri); F.J. van Oost (F.); E.J.T. Rutgers (Emiel); S. Elkhuizen (Sylvia); A.N. van Geel (Albert); L.J.E.E. Scheijmans (L. J E E); M.J.C. van der Sangen (Maurice); G. Botke (G.); C.J.M. Hoekstra (C. J M); J.J. Jobsen (Jan); C.J.H. van de Velde (Cornelis); M.F. von Meyenfeldt (Maarten); J.M. Tabak (J.); J.L. Peterse (J.); M.J. Vijver (Marc ); J.W.W. Coebergh (Jan Willem); G. van Tienhoven (Geertjan)

    2005-01-01

    textabstractWe have studied the long-term prognosis of 266 patients considered to have isolated local recurrence in the breast following conservative surgery and radiotherapy for early breast cancer. The median follow-up of the patients still alive after diagnosis of local relapse was 11.2 years. At

  11. Programmatic Life Cycle Environmental Assessment for Smoke/Obscurants. Volume 4. HC Smoke

    Science.gov (United States)

    1983-07-01

    Properties. The physical properties of hexachloroethane* are: Physical form @ 20°C: solid Color and crystalline form: colorless rhombic Odor camphor ...like "M.P. 16.80 C (triple point - sublimes simultaneously) Crystal density 2.09 Vapor density (airul) 6.3 g/l @ 16.80 C Specific heat @ 20 0 C 0.266

  12. Elliptic Curve Cryptography on Smart Cards Without Coprocessors

    Science.gov (United States)

    2000-09-20

    Lecture Notes in Computer Science , 1998...implementation for arithmetic operations in GF (2n). In Asiacrypt ’96. Springer-Verlag Lecture Notes in Computer Science , 1996. [9] E. De Win, S. Mister, B...pages 252–266, Berlin, 1998. Springer-Verlag Lecture Notes in Computer Science . [10] P. Gaudry, F. Hess, and N. P. Smart. Constructive and

  13. Positive association between blood Omega-3 index and cognition in healthy Dutch adolescents

    NARCIS (Netherlands)

    Van der Wurff, Inge; Von Schacky, Clemens; Berge, Kjetil; Zeegers, Maurice P; Kirschner, Paul A.; De Groot, Renate

    2016-01-01

    The impact of omega-3 long-chain polyunsaturated fatty acids (LCPUFAs) on cognition is heavily debated. In the current study, the possible association between omega-3 LCPUFAs in blood and cognitive performance of 266 typically developing adolescents aged 13–15 years is investigated. Baseline data fr

  14. 75 FR 63506 - Logging Operations; Extension of the Office of Management and Budget's (OMB) Approval of...

    Science.gov (United States)

    2010-10-15

    ... Occupational Safety and Health Administration Logging Operations; Extension of the Office of Management and... specified in its Standard on Logging Operations (29 CFR 1910.266). DATES: Comments must be submitted..., operation, and maintenance of tools, machines, and vehicles the worker/supervisor uses or operates, as...

  15. Farewell to the Man in the Red Beret, Enter the Man in the White Silk Mitre: "There Is a Crack in Everything, That's How the Light Gets In"

    Science.gov (United States)

    McLaren, Peter

    2013-01-01

    This essay examines the legacy of the late President of Venezuela, Hugo Chavez Frias. Shortly after the death of President Chavez, Jorge Mario Bergoglio was elected the 266th and current pope of the Catholic Church and took the name, Francis. The essay contrasts the demonization of Hugo Chavez by the Western corporate media with the adulation of…

  16. Initiation, Desistance, and Persistence of Men's Sexual Coercion

    Science.gov (United States)

    Hall, Gordon C. Nagayama; Degarmo, David S.; Eap, Sopagna; Teten, Andra L.; Sue, Stanley

    2006-01-01

    Patterns of sexually coercive behavior were examined among 266 Asian American and 299 European American men over 1 year. Noncoercer (n = 358), desister (n = 120), initiator (n = 39), and persistent (n = 48) sexually coercive groups were identified. The strongest predictor of sexual coercion was past sexual coercion. Persistent sexual coercers were…

  17. Social Studies Student Teachers' Levels of Understanding Sociology Concepts within Social Studies Curriculum

    Science.gov (United States)

    Karatekin, Kadir

    2013-01-01

    This study aims at investigating social studies student teachers' levels of understanding sociology concepts within social studies curriculum. Study group of the research consists of 266 teacher candidates attending the Department of Social Studies, Faculty of Education, Kastamonu University during 2012 to 2013 education year. A semi-structured…

  18. Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

    NARCIS (Netherlands)

    M. Smid (Marcel); F.G. Rodriguez-Gonzalez (F. German); A.M. Sieuwerts (Anieta); R. Salgado (Roberto); W.J.C. Prager-van der Smissen (Wendy); Vlugt-Daane, M.V.D. (Michelle Van Der); A. van Galen (Anne); S. Nik-Zainal (Serena); J. Staaf (Johan); A.B. Brinkman (Arie B.); M.J. Vijver (Marc ); A.L. Richardson (Andrea); A. Fatima (Aquila); Berentsen, K. (Kim); A. Butler (Adam); S. Martin (Sandra); H. Davies (Helen); J.E.M.A. Debets (Reno); M.E.M.-V. Gelder (Marion E. Meijer-Van); C.H.M. van Deurzen (Carolien); Macgrogan, G. (Gaëtan); Van Den Eynden, G.G.G.M. (Gert G. G. M.); C.A. Purdie (Colin A.); A.M. Thompson (Alastair M.); C. Caldas (Carlos); P.N. Span (Paul); Simpson, P.T. (Peter T.); S. Lakhani (Sunil); S.J. van Laere (Steven); C. Desmedt (Christine); Ringnér, M. (Markus); Tommasi, S. (Stefania); Eyford, J. (Jorunn); A. Broeks (Annegien); A. Vincent-Salomon (Anne); Futreal, P.A. (P. Andrew); S. Knappskog (Stian); King, T. (Tari); G. Thomas (Gilles); Viari, A. (Alain); Langerød, A. (Anita); A.-L. Borresen-Dale (Anne-Lise); E. Birney (Ewan); H. Stunnenberg (Henk); M.R. Stratton (Michael); J.A. Foekens (John); J.W.M. Martens (John)

    2016-01-01

    textabstractA recent comprehensive whole genome analysis of a large breast cancer cohort was used to link known and novel drivers and substitution signatures to the transcriptome of 266 cases. Here, we validate that subtype-specific aberrations show concordant expression changes for, for example, TP

  19. Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

    NARCIS (Netherlands)

    Smid, M.; Rodriguez-Gonzalez, F.G.; Sieuwerts, A.M.; Salgado, R.; Smissen, W.J. Prager-Van der; Vlugt-Daane, M.V.; Galen, A. van; Nik-Zainal, S.; Staaf, J.; Brinkman, A.B.; Vijver, M.J. van de; Richardson, A.L.; Fatima, A.; Berentsen, K.; Butler, A.; Martin, S.; Davies, H.R.; Debets, R.; Gelder, M.E. Meijer-van; Deurzen, C.H. van; MacGrogan, G.; Eynden, G.G. Van den; Purdie, C.; Thompson, A.M.; Caldas, C.; Span, P.N; Simpson, P.T.; Lakhani, S.R.; Laere, S. van; Desmedt, C.; Ringner, M.; Tommasi, S.; Eyford, J.; Broeks, A.; Vincent-Salomon, A.; Futreal, P.A.; Knappskog, S.; King, T.; Thomas, G; Viari, A.; Langerod, A.; Borresen-Dale, A.L.; Birney, E.; Stunnenberg, H.G.; Stratton, M.; Foekens, J.A.; Martens, J.W.M.

    2016-01-01

    A recent comprehensive whole genome analysis of a large breast cancer cohort was used to link known and novel drivers and substitution signatures to the transcriptome of 266 cases. Here, we validate that subtype-specific aberrations show concordant expression changes for, for example, TP53, PIK3CA,

  20. AcEST: DK956022 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ribosomal protein L8-1 OS=Arabidopsis t... 266 7e-71 sp|Q4PSL7|RL82_ARATH 60S ribosomal protein L8-2 OS=Arab...KKIVPS Sbjct: 124 GVLARASGDYAIVIAHNPDSDTTRIKLPSGSKKIVPS 160 >sp|Q4PSL7|RL82_ARATH 60S ribosomal protein L8-2

  1. The Correlation between Ultrasound Testicular Volume and Conventional Semen Parameters in Albanian Subfertile Males

    Directory of Open Access Journals (Sweden)

    Adrian Kristo

    2014-09-01

    CONCLUSION: Testicular volume has a direct correlation with semen parameters and the critical total testicular volume indicating normal testicular function is approximately 26.6 ml (the mean testicular volume 13.3 ml. The measurement of testicular volume can be helpful for assessing fertility at the initial physical examination.

  2. Main: 1SQD [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available rPro; IPR004360; Gly_bleo_diox.|Pfam; PF00903; Glyoxalase; 1.|TIGRFAMs; TIGR01263; 4HPPD; 1. X-Ray Diffrac...tion, Resolution: 1.80 Angstrom, R-Factor: 0.216, R-Free: 0.266 Length: 445 AA, Mol

  3. Parental Influence on Chinese Students' Achievement: A Social Capital Perspective

    Science.gov (United States)

    Wei, Dan

    2012-01-01

    This paper examines how social capital formed by effective parental practices within Chinese families influences student achievement. Survey responses from 266 students from Grades 4 to 6 in a suburban elementary school in China were analysed to identify their perceptions of parental practices (support, pressure, help, monitoring and…

  4. 77 FR 16585 - Arkansas Midland Railroad Company, Inc.-Abandonment Exemption-in Phillips County, AK

    Science.gov (United States)

    2012-03-21

    ..., in Phillips County, Ark. The line traverses United States Postal Service Zip Codes 72342 and 72390. AKMD has certified that: (1) No local traffic has moved over the line for at least 2 years; (2) there... CFR part 1152 subpart F-Exempt Abandonments to abandon an approximately 2.66-mile rail line known...

  5. Disorder-specific cognitive profiles in major depressive disorder and generalized anxiety disorder

    NARCIS (Netherlands)

    Hendriks, Sanne M.; Licht, Carmilla M. M.; Spijker, Jan; Beekman, Aartjan T. F.; Hardeveld, Florian; de Graaf, Ron; Penninx, Brenda W. J. H.

    2014-01-01

    Background: This investigation examines differences in cognitive profiles in subjects with major depressive disorder (MDD) and generalized anxiety disorder (GAD). Methods: Data were used from subjects with current MDD (n = 655), GAD (n = 107) and comorbid MDD/GAD (n = 266) diagnosis from the Netherl

  6. Domain Modeling: NP_660281.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_660281.2 chr1 Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain... Bound to DNA p2prta_ chr1/NP_660281.2/NP_660281.2_holo_261-368.pdb psi-blast 265T,266S,267E,268K,270Q,271G,

  7. School Counselors' and Principals' Perceptions of Violence: Guns, Gangs and Drugs in Rural Schools.

    Science.gov (United States)

    Barrow, Rosemary; VanZommeren, Wayne; Young, Clark; Holtman, Paula

    2001-01-01

    Research investigating perceptions of guns, gangs, drugs, and violence in rural schools surveyed 266 principals and counselors in rural elementary, middle, and high schools in northern Missouri. Smaller schools and elementary schools had fewer problems than larger and middle/high schools. Community collaboration is essential to solving…

  8. Dos tesis convertidas en un libro

    Directory of Open Access Journals (Sweden)

    Renán Vega Cantor

    2013-09-01

    Full Text Available Esclavos, negros libres y bogas en la literatura del siglo XIX. María Camila Nieto Villamizar y María Riaño Pradilla. Universidad de los Andes, Facultad de Ciencias Sociales, Departamento de Historia, Centro de Estudios Socioculturales e Internacionales (Ceso, Bogotá, 2011. 266 págs., il.

  9. Data of evolutionary structure change: 1VLCA-1GRPA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1VLCA-1GRPA 1VLC 1GRP A A -----------------------HMKIAVLPGDGIGPEV...09 GLU CA 266 LYS CA 331 1GRP... A 1GRPA EKAYKGERK...67 LEU CA 375 PRO CA 289 GLU CA 214 1GRP... A 1GRPA

  10. Letters

    Science.gov (United States)

    2000-04-01

    Coulombic Models in Chemical Bonding by Lawrence J. Sacks and by Derek W. Smith Re: articles by R. J. Gillespie and by D. W. Smith D. W. Smith replies Capsaicin Hazard by Paul E. Vorndam Re: article by J. D. Batchelor and B. T. Jones B. T. Jones reply Editor's Note: Hazards Re: JCE 1999, 76, 240 and JCE 2000, 77, 266.

  11. Drug: D08211 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08211 Drug Metomidate hydrochloride; Hypnodil [veterinary] (TN) C13H14N2O2. HCl 26...6.0822 266.7234 D08211.gif Hypnotic, sedative [veterinary] CAS: 35944-74-2 PubChem: 96024899 LigandBox: D082

  12. Population pharmacokinetics of abacavir in pregnant women.

    Science.gov (United States)

    Fauchet, Floris; Treluyer, Jean-Marc; Préta, Laure-Helene; Valade, Elodie; Pannier, Emmanuelle; Urien, Saik; Hirt, Déborah

    2014-10-01

    For the first time, a population approach was used to describe abacavir (ABC) pharmacokinetics in HIV-infected pregnant and nonpregnant women. A total of 266 samples from 150 women were obtained. No covariate effect (from age, body weight, pregnancy, or gestational age) on ABC pharmacokinetics was found. Thus, it seems unnecessary to adapt the ABC dosing regimen during pregnancy.

  13. Shanghai:2011,total imports of cotton up by 26.4%

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    According to Shanghai Customs statistics, in 2011, Shanghai Customs District imported a total of 959000 tons of cotton, increased by 26.4% over the previous year; worth $ 2.66 billion, an increase of 70.7%; import average price

  14. Gclust Server: 198851 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 198851 Rde_RD1_2506 Cluster Sequences - 266 hypothetical protein 1 1.00e-99 0.0 0.0... 0.0 6.67 0.0 0.0 Show 198851 Cluster ID 198851 Sequence ID Rde_RD1_2506 Link to cluster sequences Cluster S

  15. Implications of Women in the Infantry: Will This Improve Combat Efficiency?

    Science.gov (United States)

    2013-04-22

    Kinder , Gentler Military: How Political Correctness Affects Our Ability To Win Wars (San Francisco, CA: Encounter Books, 2000), 266. 157 Moore, “Canada...World War II, and is helpful in understanding why they were used and why their use was discontinued. Gutmann, Stephanie. The Kinder , Gentler

  16. Italian Preschoolers' Peer-Status Linkages with Sociability and Subtypes of Aggression and Victimization

    Science.gov (United States)

    Nelson, David A.; Robinson, Clyde C.; Hart, Craig H.; Albano, Anthony D.; Marshall, Shawna J.

    2010-01-01

    Little is known about the behavior of preschool children belonging to peer sociometric status groups (popular, average, rejected, neglected, and controversial) in cultural contexts outside North America. This study examined the social interactions of Italian preschoolers. The sample consisted of 266 Italian preschoolers (mean age of 64 months).…

  17. Lifelong Learning and the E-Strategy of the Open University of the Netherlands: ou.nl

    NARCIS (Netherlands)

    Westera, Wim; Kalz, Marco

    2008-01-01

    Westera, W., & Kalz, M. (2008). Lifelong Learning and the E-Strategy of the Open University of the Netherlands: ou.nl. In J. Stratmann & M. Kerres (Eds.), E-strategy, Strategisches Informationsmanagement für Forschung und Lehre, Medien in de Wissenschaft Band 46 (pp. 253-266). Gesellschaft für Medie

  18. 77 FR 65196 - Announcement of the Award of a Single-Source Program Expansion Supplement Grant to the Regents of...

    Science.gov (United States)

    2012-10-25

    ...) of the Child Abuse Prevention and Treatment and Adoption Reform Act (CAPTA) of 1978, (Pub. L. 95-266... HUMAN SERVICES Administration for Children and Families Announcement of the Award of a Single-Source..., MI AGENCY: Children's Bureau, Administration on Children, Youth and Families, Administration...

  19. Crystal and magnetic structure of Eusub>4sub>Ga>8sub>Ge>1sub>>6sub>

    DEFF Research Database (Denmark)

    Christensen, M.; Bryan, J.D.; Birkedal, H.

    2003-01-01

    dependence of the crystal structure was investigated from 11 K to room temperature using synchrotron x-ray powder diffraction. Analysis of the atomic displacement parameters with Einstein and Debye models gives Theta(E)=82(3) K for the guest atom and Theta(D)=266(4) K for the framework atoms. Based on Theta...

  20. Revision of the Lauraceae I

    NARCIS (Netherlands)

    Kostermans, A.J.G.H.

    1936-01-01

    Acrodiclidium Nees, Laur. Disp. Progr. (1833), p. 13; id., Syst. Laur. (1836), p. 266; Endl., Gen. (1837), p. 319, n. 2042; id., Ench. (1841), p. 197; Dietrich, Synops. Pl. II (1840), p. 1332; Spach, Hist. nat. Véget., Phaner. X (1841), p. 471; Steudel. Nomencl. ed. 2 (1841), p. 21; Meissn., Gen. I

  1. Fluorescence preselection of bioaerosol for single-particle mass spectrometry

    NARCIS (Netherlands)

    Stowers, M.A.; Van Wuijckhuijse, A.L.; Marijnissen, J.C.M.; Kientz, C.E.; Ciach, T.

    2006-01-01

    We have designed, constructed, and tested a system that preselects the biological fraction of airborne particles from the overall aerosol. The preselection is based on fluorescence emission excited by a continuous 266 nm laser beam. This beam is one of two cw beams used to measure the aerodynamic pa

  2. Psychosocial Factors Versus Single Predictors: A Factor Analytic Approach to Cardiovascular Outcomes in The Women’s Ischemia Syndrome Evaluation (WISE) Study

    Science.gov (United States)

    2010-02-18

    health care services(Bertakis, Azari, Helms, Callahan, & Robbins, 2000) and receive preventive care(Cleary, Mechanic, & Greenley , 1982) than men...treatment, and interpretation of coronary heart disease symptoms. Health Psychol, 25(3), 255-266. Cleary, P. D., Mechanic, D., & Greenley , J. R. (1982

  3. Data of evolutionary structure change: 1ACMD-2YWWB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACMD-2YWWB 1ACM 2YWW D B GVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGL... 113 THR CA 197 SER CA 218 1ACM... D 1ACMD SLFKLTE...SN CA 166 PRO CA 180 LEU CA 266 1ACM... D 1ACMD SFAVRKRANDI

  4. School District Administrators' Perspectives on the Professional Activities and Influence of Special Educators in Norway and Sweden

    Science.gov (United States)

    Cameron, David Lansing; Lindqvist, Gunilla

    2014-01-01

    The purpose of this study is to investigate school district administrators' perspectives concerning the professional activities and influence of special educators in Norway (n?=?266) and Sweden (n?=?290). We examine three themes drawn from a survey of practices and policies in each country: (a) the organisational arrangements in which special…

  5. Draft genome sequence of an aflatoxigenic Aspergillus species, A. bombycis

    Science.gov (United States)

    The genome of the A. bombycis Type strain was sequenced using a Personal Genome Machine, followed by annotation of its predicted genes. The genome size for A. bombycis was found to be approximately 37 Mb and contained 12,266 genes. This announcement introduces a sequenced genome for an aflatoxigenic...

  6. Thermal hypersensitisation and grating evolution in Ge-doped optical fibre

    DEFF Research Database (Denmark)

    Sørensen, Henrik Rokkjær; Canning, John; Kristensen, Martin

    2005-01-01

    Low temperature (sub 1000°C) thermal hypersensitisation is reported in germanosilicate optical waveguides. Gratings are written using a CW 266nm laser source. In contrast to laser hypersensitisation, thermal excitation is generally dispersive involving a range of specific glass sites. More complex...

  7. Comparison of UVB and UVC irradiation disinfection efficacies on Pseudomonas Aeruginosa biofilm

    DEFF Research Database (Denmark)

    Argyraki, Aikaterini; Markvart, M.; Nielsen, Anne;

    2016-01-01

    , on P. aeruginosa biofilms at different growth stages. In our experiments a new type of UV light emitting diodes (LEDs) were used to deliver UV irradiation on the biofilms, in the UVB (296nm) and UVC (266nm) region. The killing rate was studied as a function of dose for 24h grown biofilms. The dose...

  8. Department of the Navy Justification of Estimates for Fiscal Year 1984 Submitted to Congress January 1983. Operation & Maintenance, Navy. Book 3. Budget Activity 3: Intelligence & Communications. Budget Activity 8: Training, Medical & OGPA. Budget Activity 9: Administration & Assoc Acts. Budget Activity 10: Support to Other Nations.

    Science.gov (United States)

    1983-01-01

    1982 Budget Man Costs 5) Officer Retention$ 6) Enlisted Retention 1/ (116) (123) 7) Submarine Motivatio 2/ 79 42 UDT/SEAL 3/ 44 42 8) Officer/Enlisted...Costs 5) Officer Retention -7W ~ 4§ 4 6) Enlisted Retention 1/ 216 266 216 271 7) Submarine Motivatio 2/ 81 44 81 45 UDT/SEAL 3/ 44 43 44 44 8) Officer

  9. Creating and Sustaining School Capacity in the Twenty-First Century: Funding a Physical Environment Conducive to Student Learning.

    Science.gov (United States)

    Crampton, Faith E.; Thompson, David C.; Hagey, Janis M.

    2001-01-01

    Results of state-by-state study of unmet school infrastructure needs using multiple data sources. Found that aggregate unmet infrastructure needs of $266.1 billion were significantly larger than found in earlier studies and varied substantially among states. Suggests different short- and long-term funding strategies to address problem. Includes…

  10. Like Godfather, Like Son: Exploring the Intergenerational Nature of Crime

    Science.gov (United States)

    Hjalmarsson, Randi; Lindquist, Matthew J.

    2012-01-01

    Sons (daughters) with criminal fathers have 2.06 (2.66) times higher odds of having a criminal conviction than those with noncriminal fathers. One additional paternal sentence increases sons' (daughters') convictions by 32 (53) percent. Compared to traditional labor market measures, the intergenerational transmission of crime is lower than that…

  11. 78 FR 22899 - Certain Electronic Devices Having Placeshifting or Display Replication Functionality and Products...

    Science.gov (United States)

    2013-04-17

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE...''); U.S. Patent No. 8,266,657 (``the `657 patent''); and U.S. Patent No. 8,365,236 (``the `236 patent... business hours (8:45 a.m. to 5:15 p.m.) in the Office of the Secretary, U.S. International Trade...

  12. Two-photon photoemission from a copper cathode in an X -band photoinjector

    Science.gov (United States)

    Li, H.; Limborg-Deprey, C.; Adolphsen, C.; McCormick, D.; Dunning, M.; Jobe, K.; Raubenheimer, T.; Vrielink, A.; Vecchione, T.; Wang, F.; Weathersby, S.

    2016-02-01

    This paper presents two-photon photoemission from a copper cathode in an X -band photoinjector. We experimentally verified that the electron bunch charge from photoemission out of a copper cathode scales with laser intensity (I) square for 400 nm wavelength photons. We compare this two-photon photoemission process with the single photon process at 266 nm. Despite the high reflectivity (R ) of the copper surface for 400 nm photons (R =0.48 ) and higher thermal energy of photoelectrons (two-photon at 200 nm) compared to 266 nm photoelectrons, the quantum efficiency of the two-photon photoemission process (400 nm) exceeds the single-photon process (266 nm) when the incident laser intensity is above 300 GW /cm2 . At the same laser pulse energy (E ) and other experimental conditions, emitted charge scales inversely with the laser pulse duration. A thermal emittance of 2.7 mm-mrad per mm root mean square (rms) was measured on our cathode which exceeds by sixty percent larger compared to the theoretical predictions, but this discrepancy is similar to previous experimental thermal emittance on copper cathodes with 266 nm photons. The damage of the cathode surface of our first-generation X -band gun from both rf breakdowns and laser impacts mostly explains this result. Using a 400 nm laser can substantially simplify the photoinjector system, and make it an alternative solution for compact pulsed electron sources.

  13. 77 FR 58761 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Airplanes

    Science.gov (United States)

    2012-09-24

    ...-266-AD; Amendment 39-17201; AD 2012-19-06] RIN 2120-AA64 Airworthiness Directives; Empresa Brasileira... Transportation (DOT). ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) all Empresa... 2. The FAA amends Sec. 39.13 by adding the following new AD: 2012-19-06 Empresa Brasileira...

  14. Kasumi jaotamine aktsiaseltsis : [bakalaureusetöö] / Risto Vahimets ; Tartu Ülikool, õigusteaduskond ; juhendaja: Andres Vutt

    Index Scriptorium Estoniae

    Vahimets, Risto, 1974-

    1996-01-01

    Kasumijaotamise üldmõisted (viisid aktsiaseltsis, omakapitali mõisted, jaotised, dividendid, eelisaktsiad, mitterahaline vara, uute aktsiate jagamine, reservfond, varjatud kasumijaotamine); kasumijaotamise reeglid Euroopa Liidus; Eesti äriseadustik ja Euroopa Liidu direktiivid; kasumijaotamine Soome Vabariigis. Vt. ka: Juridica (1996) nr. 6, lk. 266-268

  15. The Measurement and Conceptualization of Curiosity

    Science.gov (United States)

    Reio, Thomas G., Jr.; Petrosko, Joseph M.; Wiswell, Albert K.; Thongsukmag, Juthamas

    2006-01-01

    In this study, the authors tried various methods to measure and conceptualize curiosity. A sample of 369 education students (103 men, 266 women) who were attending universities on the East Coast of the United States completed 5 paper-and-pencil curiosity measures in 1 of their classes. Using confirmatory factor analysis, the authors found that the…

  16. Characterizing and Optimizing the Performance of the MAESTRO 49-Core Processor

    Science.gov (United States)

    2014-03-27

    DDR memory controllers which are now compatible with both DDR1 and DDR2 memory. [17] In addition to creating the MAESTRO board, OPERA also produced the...GFLOPS (Peak) — single or double precision 25 XAUI Interfaces (4) (errata: half duplex) 10 GBPS (each — half duplex) DDR2 rate (4) 266 MHZ (each

  17. Developmental Trajectories of Acculturation in Hispanic Adolescents: Associations with Family Functioning and Adolescent Risk Behavior

    Science.gov (United States)

    Schwartz, Seth J.; Des Rosiers, Sabrina; Huang, Shi; Zamboanga, Byron L.; Unger, Jennifer B.; Knight, George P.; Pantin, Hilda; Szapocznik, Jose

    2013-01-01

    This study examined longitudinal acculturation patterns, and their associations with family functioning and adolescent risk behaviors, in Hispanic immigrant families. A sample of 266 Hispanic adolescents (M[subscript age] = 13.4) and their primary parents completed measures of acculturation, family functioning, and adolescent conduct problems,…

  18. Proof of the Feasibility of Coherent and Incoherent Schemes for Pumping a Gamma-Ray Laser

    Science.gov (United States)

    1993-08-31

    180Ta sits somewhat aside the main path of the s pro- intensities up to an end point energy Eo is, ces-") for cosmic nucleosynthesis and the survival...details of the calculations, including negative parity I h-states which effectively 12 Volume 266 number 12 PHYtICS I SU TTERS It 22 August 1991 a0 exen

  19. Photodestruction of NO2- using time resolved multicoincidence detection photofragment spectroscopy

    NARCIS (Netherlands)

    Dinu, L.; Zande, W.J. van der

    2004-01-01

    We present an experiment on the photodestruction of the NO2- anion at 266 nm. We have quantified the competition between photodetachment and photodissociation and have identified the nature of the photodissociation process from the photofragment angular distribution. This study involves a novel tech

  20. Mechanism of Transcriptional Regulation by Androgen Receptor and its Coactivators in the Context of Chromatin

    Science.gov (United States)

    2002-07-01

    caso - reaction and the mixture was incubated for 20 min at roomteprtr.In co petition says, unlabeled ARE or TRE 󈧎 dex and flutamide. We are...activation and nuclear targeting sig- nals of the human androgen receptor. J Biol Chem 266: LNCaP cells were culture in Roswell Park Memorial Institute 510

  1. Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.

    Directory of Open Access Journals (Sweden)

    Patrick Auberger

    2013-06-01

    Full Text Available A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2, along with the previously described nepheliosyne A (1, have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.

  2. Articulating Syntactic and Numeric Perspectives on Equivalence: The Case of Rational Expressions

    Science.gov (United States)

    Solares, Armando; Kieran, Carolyn

    2013-01-01

    Our study concerns the conceptual mathematical knowledge that emerges during the resolution of tasks on the equivalence of polynomial and rational algebraic expressions, by using CAS and paper-and-pencil techniques. The theoretical framework we adopt is the Anthropological Theory of Didactics ("Chevallard" 19:221-266, 1999), in…

  3. Data of evolutionary structure change: 1CERO-3CIFC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1CERO-3CIFC 1CER 3CIF O C -MKVGINGFGRIGRQVFRILHSRG-VEVALINDL-TDNK...434 ALA CA 375 LEU CA 455 3CIF C 3CIFC CMERNDIT.../line> LYS CA 254 THR CA 266 3CIF... C 3CIFC AINDPFMDVEY

  4. Polysemy Advantage with Abstract but Not Concrete Words

    Science.gov (United States)

    Jager, Bernadet; Cleland, Alexandra A.

    2016-01-01

    It is a robust finding that ambiguous words are recognized faster than unambiguous words. More recent studies (e.g., Rodd et al. in "J Mem Lang" 46:245-266, 2002) now indicate that this "ambiguity advantage" may in reality be a "polysemy advantage": caused by related senses (polysemy) rather than unrelated meanings…

  5. Agents that increase phosphatidic acid inhibit the LH-induced testosterone production

    DEFF Research Database (Denmark)

    Lauritzen, L.; Nielsen, L.-L.A.; Vinggaard, Anne Marie;

    1994-01-01

    The results of the present study point to phosphatidic acid (PtdOH) as a possible intracellular messenger, which might be involved in local modulation of testicular testosterone production in vivo. Propranolol (27-266 µM) induced an increased level of [H]PtdOH in isolated rat Leydig cells, prelab...

  6. Technological Literacy and Political Participation in McLean County, Illinois.

    Science.gov (United States)

    Welty, Kenneth

    1992-01-01

    A survey of 266 residents of McLean County, Illinois, found that 91 percent believe technology makes life easier; 70 percent believe people are too technologically dependent; those with a history of political participation felt confident engaging in political activities regarding nuclear power, automation, and genetic engineering; and the public…

  7. Domain Modeling: NP_775927.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_775927.1 chr3 COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA c1f2il_ chr3/NP_775927....1/NP_775927.1_holo_204-266.pdb blast 214K,218C,221C,223K,224T,225F,226R,227Y,230K,233R,2

  8. Set9, NF-kB, and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells

    Institute of Scientific and Technical Information of China (English)

    Hai-yan HU; Kun-peng LI; Xiu-ju WANG; Yuan LIU; Zhi-gang LU; Rui-hong DONG; Hong-bo GUO; Mei-xia ZHANG

    2013-01-01

    Aim:To investigate the mechanisms by which berberine suppressed the proliferation of human multiple myeloma cells.Methods:Human U266 multiple myeloma cell line was tested.Cell proliferation,apoptosis,ultramicrostructure and secretion function were examined using Cell Counting Kit-8 (CCK8),flow cytometry (FCM),electron and fluorescence microscopy,as well as ELISA assay.The microRNAs (miRs) and transcription factors in U266 cells were detected using arrays and verified by qRT-PCR.EMSA and luciferase assays were used to verify the p65-dependent transactivation of miR-21 gene.Results:Treatment of U266 cells with berberine (40-160 μmol/L) suppressed cell proliferation and IL-6 secretion in dose-and time-dependent manners.Meanwhile,berberine dose-dependently induced ROS generation,G2/M phase arrest and apoptosis in U266 cells,and decreased the levels of miR-21 and Bcl-2.Overexpression of miR-21 counteracted berberine-induced suppression of cell proliferation and IL-6 secretion.In U266 cells treated with berberine (80 μmol/L),the activity of NF-kB was decreased by approximately 50%,followed by significant reduction of miR-21 level.berberine (80-160 μmol/L) increased the level of Set9 (lysine methyltransferase) by more than 2-fold,caused methylation of the RelA subunit,which inhibited NF-kB nuclear translocation and miR-21transcription.In U266 cells treated with berberine (80 μmol/L),knockdown of Set9 with siRNAs significantly increased NF-kB protein level accompanying with a partial recovery of proliferation.Conclusion:In U266 cells,berberine suppresses NF-kB nuclear translocation via Set9-mediated lysine methylation,leads to decrease in the levels miR21 and Bcl-2,which induces ROS generation and apoptosis.

  9. A novel congenital myasthenic syndrome due to decreased acetylcholine receptor ion-channel conductance.

    Science.gov (United States)

    Webster, Richard; Maxwell, Susan; Spearman, Hayley; Tai, Kaihsu; Beckstein, Oliver; Sansom, Mark; Beeson, David

    2012-04-01

    Muscle acetylcholine receptor ion channels mediate neurotransmission by depolarizing the postsynaptic membrane at the neuromuscular junction. Inherited disorders of neuromuscular transmission, termed congenital myasthenic syndromes, are commonly caused by mutations in genes encoding the five subunits of the acetylcholine receptor that severely reduce endplate acetylcholine receptor numbers and/or cause kinetic abnormalities of acetylcholine receptor function. We tracked the cause of the myasthenic disorder in a female with onset of first symptoms at birth, who displayed mildly progressive bulbar, respiratory and generalized limb weakness with ptosis and ophthalmoplegia. Direct DNA sequencing revealed heteroallelic mutations in exon 8 of the acetylcholine receptor ε-subunit gene. Two alleles were identified: one with the missense substitution p.εP282R, and the second with a deletion, c.798_800delCTT, which result in the loss of a single amino acid, residue F266, within the M2 transmembrane domain. When these acetylcholine receptor mutations were expressed in HEK 293 cells, the p.εP282R mutation caused severely reduced expression on the cell surface, whereas p.εΔF266 gave robust surface expression. Single-channel analysis for p.εΔF266 acetylcholine receptor channels showed the longest burst duration population was not different from wild-type acetylcholine receptor (4.39 ± 0.6 ms versus 4.68 ± 0.7 ms, n = 5 each) but that the amplitude of channel openings was reduced. Channel amplitudes at different holding potentials showed that single-channel conductance was significantly reduced in p.εΔF266 acetylcholine receptor channels (42.7 ± 1.4 pS, n = 8, compared with 70.9 ± 1.6 pS for wild-type, n = 6). Although a phenylalanine residue at this position within M2 is conserved throughout ligand-gated excitatory cys-loop channel subunits, deletion of equivalent residues in the other subunits of muscle acetylcholine receptor did not

  10. AcEST: BP913035 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YMU001_000025_F10 266 Adiantum capillus-veneris mRNA. clone: YMU001_000025_F10. BP91303...5 CL1254Contig1 Show BP913035 Clone id YMU001_000025_F10 Library YMU01 Length 266 Definition Adiantum ca...pillus-veneris mRNA. clone: YMU001_000025_F10. Accession BP913035 Tissue type prothallium Developmental stag...and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= BP91303...T and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= BP91303

  11. Correction of walk-off-induced wavefront distortion for continuous-wave laser

    Science.gov (United States)

    Zou, Hongxin; Chen, Guozhu; Wu, Yue; Shen, Yong; Liu, Qu

    2016-09-01

    We theoretically and experimentally investigate the wave front distortion in critically phase-matched continuous-wave (CW) second harmonic generation (SHG). Due to the walk-off effect in the nonlinear crystal, the generated second harmonic is extremely elliptical and quite non-Gaussian, which causes a very low matching and coupling efficiency in experiment. Cylindrical lenses and walk-off compensating crystals are adopted to correct distorted wave fronts, and obtain a good TEM00 mode efficiently. Theoretically, we simulate the correction effect of 266-nm laser generated with SHG. The experiment results accord well with the theoretical simulation and an above 80% TEM00 component is obtained for 266-nm continuous-wave laser with a 4.8°-walk-off angle in beta barium borate (BBO) crystal. Project supported by the National Natural Science Foundation of China (Grant No. 91436103) and Research Programme of National University of Defense Technology, China (Grant No. JC15-02-03).

  12. Factors influencing the attitudes of Chinese cancer patients and their families toward the disclosure of a cancer diagnosis.

    Science.gov (United States)

    Sun, Wenwen; Wang, Zhehai; Fang, Shu; Li, Minmin

    2015-03-01

    The disclosure of a cancer diagnosis to patients has been a core topic in oncology departments. Previous studies have demonstrated that Chinese cancer patients and their families differ in their attitudes toward cancer diagnosis disclosure. However, the influencing factors regarding their different attitudes remain unknown. In the present study, a questionnaire was delivered to 266 cancer patients and 266 matched family members. The results showed that cancer patients were more likely to desire to be informed of their condition than family members (85 vs. 18%, P cancer, 16.5% expected to reduce the severity of their condition, and 4.9% expected to lengthen their lives. Therefore, physicians have a responsibility to appropriately provide knowledge regarding cancer to the patients' families if their educational level is lower and if they have no knowledge of recent treatments, which may improve their acceptability of a cancer diagnosis for patients.

  13. Prevalência de parasitoses intestinais na cidade de Eirunepé, Amazonas Prevalence of intestinal parasitosis in the city of Eirunepé, Amazon

    Directory of Open Access Journals (Sweden)

    Claudio Fernández Araujo

    2005-02-01

    Full Text Available Foram analisadas, pelo método de sedimentação espontânea, amostras de fezes de 413 pacientes e encontrada positividade em 266 (64,4% dos seguintes parasitas: Ascaris lumbricoides (35,6%; Trichuris trichiura (18,6%; Ancilostomídeos(9,9%, Strongyloides stercoralis (1%, Enterobius vermiculares (0,5%, e Entamoeba histolytica (13,3% e Giardia lamblia (1%.Samples of 413 patient were analyzed and positivity was found in 64.4% (266 of the exams. The intestinal parasites most prevalent were: Ascaris lumbricoides (35.6%; Trichuris trichiura (18.6%; Ancylostomides (9.9%; Strongyloides stercoralis (1%, Enterobius vermiculares (0,5%; Entamoeba histolytica (13.3% and Giardia lamblia (1%. The presence of varied degrees of anemia were detected in 39.8% of the exams.

  14. Effect of antimicrobial on mechanical, barrier and optical properties of corn starch based self-supporting edible film

    Directory of Open Access Journals (Sweden)

    Tanima Chowdhury

    2013-10-01

    Full Text Available Antimicrobials like potassium sorbate, sodium propionate, and benzoic acid were incorporated in corn starch based formulation to investigate their effect on mechanical, water vapour barrier and optical properties of the developed self supporting edible film. The film was prepared by casting technique. When incorporated at 1.40% and above, potassium sorbate decreased the tensile strength (about 22% and increased the elongation (about 55% of control film; whereas, it increased the water vapour permeability by 15% only when added at 2.66%. At 2.66%, benzoic acid reduced the tensile strength by 24% and sodium propionate increased elongation by 17%. These two antimicrobials did not change the water vapour permeability. However, all the three antimicrobials adversely affected the optical properties by decreasing the whiteness index, increasing yellowness index, and reducing the surface gloss, with potassium sorbate showing the maximum effect. Among the three antimicrobials, sodium propionate appeared to be the best with minimum deterioration of film properties.

  15. 牙龈卟啉单胞菌菌毛融合抗原基因果实特异表达载体的构建及意义%Construction and significance of a vector for fruit-specific expression of porphyromonas gingivalis fimbriae fusion antigen gene

    Institute of Scientific and Technical Information of China (English)

    戴海燕; 王华; 文少敏; 解娜

    2011-01-01

    Objective To construct a vector for tomato fruit-specific expression of porphyromonas gingivalis fimbriae fusion antigen gene and to enhance the expression levels of the antigen gene as well as its immunogenicity, as the first step toward achieving its expression in tomato fruit and the development of an effective transgenic plant vaccine for periodontitis. Methods PCR was performed to collect the fragment (about 1.11 kb) of the tomato fruit-specific promoter E8. Meanwhile, a recombinant fragment containing the cholera toxin B subunit (CTB) and FimA (266-337) (about 600 bp) genes was linked together with the use of a soft connector using gene splicing by overlap extension, resulting in a recombinant E8CTB-FimA (266-337) fragment, which then together with the plant expression vector pBI121 underwent double restriction enzyme digestion. The recombinant vector pBI£8-CTB-FimA (266-337) was obtained after joining the restriction enzymedigested fragments and was characterized by restriction enzyme digestion and sequencing methods. Results Results from gene sequencing and restriction enzyme digestion indicated successful construction of the recombinant plasmid. Conchiskm In this study, a vector for tomato fruit-specific expression that contains the porphyromonas gingivalis fimbriae fusion antigen gene has been successfully constructed; the vector can be used in the development of a transgenic plant vaccine for periodontitis.%目的 构建含牙龈卟啉单胞菌菌毛融合抗原基因的番茄果实特异表达载体,并提高抗原基因的表达量和免疫原性,为其在番茄果实内表达和研制有效的转基因植物牙周炎疫苗奠定基础.方法 通过PCR获得番茄果实特异表达启动子E8的核心序列片段(约1.11 kb),同时合成通过柔性接头连接的霍乱毒素B亚基(Cholera Toxin B Subunit,CTB)和牙龈卟啉单胞菌菌毛FimA(266-337)(约600 bp)序列的基因片段,利用重叠区扩增基因拼接法将两基因片段

  16. Excitation wavelength dependence of water-window line emissions from boron-nitride laser-produced plasmas.

    Science.gov (United States)

    Crank, M; Harilal, S S; Hassan, S M; Hassanein, A

    2012-02-01

    We investigated the effects of laser excitation wavelength on water-window emission lines of laser-produced boron-nitride plasmas. Plasmas are produced by focusing 1064 nm and harmonically generated 532 and 266 nm radiation from a Nd:YAG laser on BN target in vacuum. Soft x-ray emission lines in the water-window region are recorded using a grazing-incidence spectrograph. Filtered photodiodes are used to obtain complementary data for water-window emission intensity and angular dependence. Spectral emission intensity changes in nitrogen Ly-α and He-α are used to show how laser wavelength affects emission. Our results show that the relative intensity of spectral lines is laser wavelength dependent, with the ratio of Ly-α to He-α emission intensity decreasing as laser wavelength is shortened. Filtered photodiode measurements of angular dependence showed that 266 and 532 nm laser wavelengths produce uniform emission.

  17. First thermochemical property of Seaborgium determined

    Energy Technology Data Exchange (ETDEWEB)

    Tuerler, A. for a LBNL Berkeley - Univ. Bern - FLNR Dubna -GSI Darmstadt - TU Dresden - Chalmers Univ. of Technology Goeteborg - GH Kassel - ITS and LLNL Livermore - Univ. Mainz - Univ. Oslo - FZ Rossendorf - JAERI Tokai - PSI Villigen collaboration

    1997-09-01

    The chemical properties of SgO{sub 2}Cl{sub 2} (element 106 = Seaborgium, Sg) were successfully studied using the On-line Gas Chromatography Apparatus (OLGA III). After chemical separation of Sg the nuclides {sup 265}Sg and {sup 266}Sg were unambiguously identified and their half-lives were determined for the first time. The Sg nuclides were produced from the {sup 248}Cm({sup 22}Ne,4,5n){sup 266,265}Sg reaction at the GSI Darmstadt UNILAC accelerator. Simultaneously, short-lived W nuclides were produced from a small admixture of {sup 152}Gd to the Cm target material. As predicted by relativistic calculations and by extrapolations of chemical properties, it was demonstrated that Sg oxychlorides are indeed less volatile than their lighter homologue Mo- and equally or less volatile than W-oxychlorides. (author) 1 fig., 1 tab., 4 refs.

  18. Wavelength dependence of repetitive-pulse laser-induced damage threshold in beta-BaB2O4.

    Science.gov (United States)

    Kouta, H

    1999-01-20

    The dependence on wavelength of repetitive-pulse (10 Hz, 8-10 ns) laser-induced damage on beta barium metaborate (BBO) has been investigated. The thresholds of dielectric breakdown in bulk crystal have been found to be 0.3 GW/cm(2) at 266 nm, 0.9 GW/cm(2) at 355 nm, 2.3 GW/cm(2) at 532 nm, and 4.5 GW/cm(2) at 1064 nm. Results indicate two-photon absorption at 266 and 355 nm, which helps to produce an avalanche effect that causes breakdown at each of the four wavelengths tested. Neither the BBO refractive indices nor the absorption spectrum change until breakdown occurs.

  19. Synthesis of Pinoxaden%除草剂唑啉草酯的合成研究

    Institute of Scientific and Technical Information of China (English)

    万琴

    2015-01-01

    以2,6-二乙基-4-甲基苯胺为原料,经重氮化、偶联、醇解、酯胺解,最后与特戊酰氯酯化,制备得到唑啉草酯。产品质量分数大于97%,收率为26.6%(以2,6-二乙基-4-甲基苯胺计)。%Using 2,6-diethyl-4-methylaniline as starting material, pinoxaden was synthesized by diazotization, coupling, alcoholysis, ammonolysis and esterification. The purity of pinoxaden was more than 97%, and the total yield was 26.6%.

  20. Cerebral toxoplasmosis in Danish AIDS patients

    DEFF Research Database (Denmark)

    Smith, E; Pers, C; Aschow, C;

    1991-01-01

    We estimate the frequency of central nervous system (CNS) toxoplasmosis in Danish AIDS patients and evaluate the diagnostic accuracy using the following criteria for acceptance of the diagnosis: either (1) the demonstration of Toxoplasma gondii in brain tissue or (2) one or more hypodense or ring......-enhancing lesions on computerized axial tomography (CAT) scan and a neurologic and CAT scan improvement in response to 2 weeks of treatment. From 1981 until July 1990 266 patients were diagnosed with AIDS at Hvidovre Hospital, Copenhagen and 29 (11%) were treated, suspected for CNS toxoplasmosis. 17 patients had...... the diagnosis confirmed but since 5 patients, who were never treated, were diagnosed at autopsy, the overall cumulated incidence was 8% (22/266 patients). The overall diagnostic accuracy was 59% (17/29 patients) showing some changes over time. Among patients diagnosed with AIDS in 1988 or later, the accuracy...

  1. Ultrafast transient absorption spectrum of the room temperature Ionic liquid 1-hexyl-3-methylimidazolium bromide: Confounding effects of photo-degradation

    Science.gov (United States)

    Musat, Raluca M.; Crowell, Robert A.; Polyanskiy, Dmitriy E.; Thomas, Marie F.; Wishart, James F.; Katsumura, Yosuke; Takahashi, Kenji

    2015-12-01

    The photochemistry of the charge transfer (CT) band of the room temperature ionic liquid (RTIL) 1-hexyl-3-methylimidazolium bromide (HMIm+/Br-) is investigated using near-IR to vis ultrafast transient absorption (TA) and steady-state UV absorption spectroscopies. Continuous irradiation of the CT band at 266 nm results in the formation of photo-products that absorb strongly at 266 nm. It is shown that these photo-products, which are apparently very stable, adversely affect ultrafast TA measurements. Elimination of these effects reveals at least two transient species that exist within the TA detection window of 100 fs to 3 ns and 500-1250 nm. One of the components is a short-lived (mechanism.

  2. Spectroscopic analysis of LYSO:Ce crystals

    Science.gov (United States)

    Martins, A. F.; Carreira, J. F. C.; Rodrigues, J.; Sedrine, N. Ben; Castro, I. F. C.; Correia, P. M. M.; Veloso, J. F. C. A.; Rino, L.; Monteiro, T.

    2017-02-01

    Rare earth orthosilicates are among the most widely used scintillator materials in the last decades. Particularly, lutetium-yttrium oxyorthosilicate (LYSO) is known to exhibit great potentialities in the field of radiation detectors for medical imaging. Consequently, an in-depth knowledge of the material properties is of utmost interest for the mentioned applications. In this work the spectroscopic properties of commercial cerium doped lutetium-yttrium oxyorthosilicate crystals (LYSO:Ce) were investigated by Raman spectroscopy, steady state photoluminescence, photoluminescence excitation and time resolved photoluminescence. Site selective excitation was used under steady state (325 nm) and pulsed (266 nm) conditions to separately investigate the temperature dependence of the 5d → 4f Ce1 and Ce2 luminescence, allowing to establish the thermal quenching dependence of the Ce2 optical center. In the case of the Ce1 optical center, a luminescence quantum efficiency of 78% was obtained from 14 K to room temperature with 266 nm photon excitation.

  3. A new X-ray transient, IGR J17451-3022, discovered by INTEGRAL/JEM-X near the Galactic Centre

    DEFF Research Database (Denmark)

    Chenevez, Jérôme; Vandbaek Kroer, L.; Budtz-Jørgensen, Carl;

    2014-01-01

    The JEM-X twin X-ray monitors on board the INTEGRAL satellite has detected a new X-ray transient during recent observations of the Galactic Centre and Bulge regions. The new source named IGR J17451-3022 has the following coordinates: R.A. = 266.27 Dec. = -30.38 with a 2arcmin 90% confidence radius...... instrument, only 26 arcsec from the JEM-X position, at the enhanced position : R.A. = 266.27824 Dec. = -30.37876 with a 90% error confidence of 2.1 arcsec. Further analysis of the Swift data is on-going. We thank the Swift team for having performed this observation of the new transient source. Multi...

  4. UV fluorescence lidar detection of bioaerosols

    Science.gov (United States)

    Christesen, Steven D.; Merrow, Clifton N.; Desha, Michael S.; Wong, Anna; Wilson, Mark W.; Butler, John C.

    1994-06-01

    A UV fluorescence lidar system for the remote detection of bioaerosols has been built and tested. At the heart of the UV- LIDAR Fluorosensor system are a 200 mJ quadrupled Nd:YAG laser at 266 nm and a 16-inch Cassagrain telescope. Operating on three data collection channels, the UV lidar is capable of real time monitoring of 266 nm elastic backscatter, the total fluorescence between 300 and 400 nm, and the dispersed fluorescence spectrum (using a small spectrograph and gated intensified CCD array). Our goal in this effort was to assess the capabilities of biofluorescence for quantitative detection and discrimination of bioaerosols. To this end, the UV-LIDAR Fluorosensor system was tested against the aerosolized bacterial spore Bacillus subtilus var. niger sp. globiggi (BG) and several likely interferences at several ranges from approximately 600 to 3000 m. Our tests with BG indicate a detection limit of approximately 500 mg/cubic meter at a range of 3000 m.

  5. Photolysis of a Benzyne Precursor Studied by Time-Resolved FTIR Spectroscopy.

    Science.gov (United States)

    Torres-Alacan, Joel

    2016-02-01

    The 266 nm laser flash photolysis of phtaloyl peroxide (2) in liquid acetonitrile solution at room temperature has been investigated. Upon 266 nm laser irradiation, 2 is effectively photodecarboxylated leading to the formation of o-benzyne (1) and two equivalents of CO2, yet a small fraction of photolyzed 2 follows a different pathway leading to 6-oxocyclohexa-2,4-dienylideneketene (3) and one equivalent of CO2. Compound 3 is kinetically reactive and reacts in the microsecond time scale following a first-order kinetic law. The presence of 1 in the photolysis experiment is confirmed by trapping experiments with methyl 1-methylpyrrole-2-carboxylate (6). The Diels-Alder reaction between 1 and 6 occurs under the selected experimental conditions on a time scale shorter than 100 ms.

  6. Ultraviolet photodissociation of hydrogen iodide complexes

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, J.; Dulligan, M.; Wittig, C. [Univ. of Southern California, Los Angeles, CA (United States)

    1995-12-01

    Binary hydrogen halide complexes are useful for studying photoinitiated reactions and inelastic processes at ultraviolet wavelengths where hydrogen halides undergo direct photodissociation. In this work, photo-initiated processes in (HI){sub 2} are investigated at 266 nm. This study has been carried out by measuring the atomic hydrogen velocity distributions via high-n Rydberg time-of-flight (HRTOF) spectroscopy, and the translational energy distributions of the hydrogen atom products have been obtained.

  7. Genistein inhibits the proliferation of human multiple myeloma cells through suppression of nuclear factor-κB and upregulation of microRNA-29b.

    Science.gov (United States)

    Xie, Jie; Wang, Jianchao; Zhu, Bo

    2016-02-01

    Multiple myeloma (MM) is a malignant tumor and is the most common primary tumor of the bone marrow in the USA. Genistein is predominantly found in Leguminosae and various lines of evidence have indicated that it suppresses cell growth, induces programmed cell death and inhibits angiogenesis. As a result of these capabilities, genistein presents as a promising cancer chemopreventive agent. However, the effect of genistein on MM remains to be elucidated. The present study investigated the effect of genistein on the proliferation and apoptosis of MM cells through the regulation of nuclear factor-κB (NF-κB) and microRNA-29b (miR-29b). In the present study, cell proliferation was examined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. In addition, apoptosis was detected using an Annexin V-fluorescein isothiocyanate/propidium iodide apoptosis assay and caspase-3 activation assay. The expression of NF-κB and miR-29b was analyzed using western blotting and reverse transcription quantitative polymerase chain reaction, respectively. Finally, miR-29b and anti-miR-29b plasmids were transfected into U266 cells to determine the effect of genistein on MM. In the present study, the results demonstrated that genistein could significantly reduce cell proliferation, induce apoptosis and increase the activity of caspase-3 in U266 cells. Furthermore, it was found that genistein could suppress the protein level of NF-κB and promote the expression of miR-29b in U266 cells. The results also indicated that miR-29b could alter the expression of NF-κB in U266 cells. These findings suggest that genistein inhibits the proliferation of human MM cells by upregulating miR-29b resulting in suppression of NF-κB.

  8. Drug: D06482 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06482 Drug Thyroid (USP); Thyradin (TN) Thyroid hormone Same as: C08215 thyroid ho...:br08310] Nuclear receptors Thyroid hormone like receptors Thyroid hormone recept...or (THR) thyroid hormone receptor, alpha [HSA:7067] [KO:K05547] Thyroid D06482 Thyroid (USP) thyroid hormone... receptor, beta [HSA:7068] [KO:K08362] Thyroid D06482 Thyroid (USP) CAS: 8028-36-2 PubChem: 47208138 NIKKAJI: J209.266B ...

  9. Workshop on Solutions and Approaches for Alleviating Hypoxia in the Gulf of Mexico.

    Science.gov (United States)

    2007-11-02

    of hvPOXia. Dr. Robert Diaz, VIMS; Dr. Andrew Solow , WHOI. Sources and loads of nutrients transported to the Gulf pf MexipQ. Dr. Donald Goolsby...389-0508 fax: (504)389-0506 Cynthia Sarthou Gulf Restoration Network 400 Magazine St. New Orleans, LA 70130 phone:(504)525-1528 Robert E...266-8513 Lafayette, Louisiana 13 Robert Twilley USL P.O. Box 42451 Lafayette, LA 70504 rtwilley@usl.edu phone: (318)482-6146 fax:(318

  10. TE/TM (Transverse Magnetic/Transverse Electric) Height Profile Measurements of Transpolar VLF (Very Low Frequency) Signals,

    Science.gov (United States)

    1987-10-01

    GQD U.K. 096 3740 [NA]’ 19.6 GBZ Criggion, U.K. 096 3740 10, 20.25 IDO Rome, Italy 086 5260 [NA] 21.4 NSS Annapolis, Md. 190 4180 266 23.4 NPM Haiku ...night no yes yes 23.4 Haiku , Hawaii night no yes yes 24.8 Jim Creek, Wash. night no yes yes 26.1 TACAMO night no no yes 50 TE 40 TM -- 30- M 20- 10

  11. Aquatic Toxicity Screening of an ACWA Secondary Waste, GB-Hydrolysate

    Science.gov (United States)

    2009-01-01

    toxicity the bioassay must include a minimum of four dilutions exhibiting a dose response, plus a control consisting of V.fischeri bioluminescent...typically used in the preliminary screening process and is not intended to be a substitute for risk assessment. This system assigns a score (0-9; 9 being...Aquatic Toxicological Research with Organophosphate Insecticides. Ecotoxicology Environmental Saf 1991, 21 (3), pp 266-274. 10. Maas, J.L. Toxicity of

  12. The impact of meningococcal polymerase chain reaction testing on laboratory confirmation of invasive meningococcal disease.

    LENUS (Irish Health Repository)

    Drew, Richard J

    2012-03-01

    Laboratory methods of diagnosis were examined for 266 children with invasive meningococcal disease. Seventy-five (36%) of 207 cases with bloodstream infection had both positive blood culture and blood meningococcal polymerase chain reaction (PCR), 130 (63%) negative blood culture and positive blood PCR, and 2 (1%) had positive blood culture and negative blood PCR. Sixty-three percent of cases were diagnosed by PCR alone.

  13. A Model of the Traveling Charge

    Science.gov (United States)

    1980-07-01

    covolume correction for other values of y to be unnecessary in view of the smallness of the correction. The stagnation temperature and pressure are...instant, either due to a prespecified pres- sure dependent burning rate or as a consequence of satisfying the pre- determined condition on the pressure ...propellant depends on the distri- bution of pressure . Evidently we have the relation 2.6.6 where Pp is assumed to be related to a according to the

  14. A Theoretical Strategy to Generate an Isolated 80-Attosecond Pulse

    Institute of Scientific and Technical Information of China (English)

    GUO Fu-Ming; YANG Yu-Jun; JIN Ming-Xing; DING Da-Jun; ZHU Qi-Ren

    2009-01-01

    Using a linearly polarized, phase-stabilized 2.66-femtcsecond driving pulse of 400 nm central wavelength orthogonally combined with another linearly polarized long pulse of 800nm central wavelength irradiating jointly on the helium atom, we demonstrate theoretically the generation of a clean isolated 80-attosecond pulse in the spectral region of 93-155 electron volts in a two-dimensional model.

  15. A flexible porous Cu(II) bis-imidazolate framework with ultrahigh concentration of active sites for efficient and recyclable CO2 capture.

    Science.gov (United States)

    Zhou, Dong-Dong; He, Chun-Ting; Liao, Pei-Qin; Xue, Wei; Zhang, Wei-Xiong; Zhou, Hao-Long; Zhang, Jie-Peng; Chen, Xiao-Ming

    2013-12-28

    By virtue of planar Cu2(μ-OH)2(2+) cluster units, a flexible porous metal azolate framework not only adsorbs large amounts of CO2 (19.6 wt% or 266 g L(-1) at 298 K and 1 atm) with a high zero-coverage adsorption enthalpy (-47 kJ mol(-1)), but also desorbs quickly at very low temperatures.

  16. A Variational Framework for Simultaneous Motion Estimation and Restoration of Motion-Blurred Video (PREPRINT)

    Science.gov (United States)

    2007-08-01

    A VARIATIONAL FRAMEWORK FOR SIMULTANEOUS MOTION ESTIMATION AND RESTORATION OF MOTION-BLURRED VIDEO By Leah Bar Benjamin Berkels Martin Rumpf and...Numerical Simulation University of Bonn, Germany benjamin.berkels@ins.uni-bonn.de Martin Rumpf Institute for Numerical Simulation University of Bonn...Image Processing, 10, no. 2:266 – 277, 2001. 6, 7 [6]D. Cremers and S. Soatto. Motion competition: A variotional approach to piecewiese parametric

  17. Influence Operations: Redefining the Indirect Approach

    Science.gov (United States)

    2011-06-01

    disemboweled; and human bonfires were set. Sendero socialized its young recruits to violence; children of five and six were taught to kill chickens so...profile bombings of hotels and embassies including the Bali bombings of 2002. From 2002– 2005, JI was the most lethal terrorist group in the world.266... hotel bombings in Jakarta through links with Al-Qaeda.‖ International Centre for Political Violence and Terrorism Research, Monthly Informatics Report

  18. Screening reading comprehension in adults: Development and initial evaluation of a reading comprehension measure

    OpenAIRE

    Proyer, René T.; Wagner-Menghin, Michaela M; Gyöngyi Grafinger

    2014-01-01

    Reading comprehension in adults is a rather neglected variable in the practice of psychological assessment. We propose a new screening instrument for adult reading comprehension based on a pragmatic definition of reading comprehension as the textual understanding of the text read. Using data from a calibration sample (n = 266) and a replication sample (n = 148) for cross-validation, we tested the model fit for the 1-PL model (Rasch-model; graphic model test, Anderson’s Conditional Likelihood-...

  19. Cultura material y esclavitud afro-opita

    Directory of Open Access Journals (Sweden)

    José Eduardo Rueda Enciso

    2014-03-01

    Full Text Available Los esclavos en las haciendas de la provincia de Neiva durante el siglo XVIII. Arqueología histórica de la Nueva Granada. María Angélica Suaza Español. Gobernación del Huila, Secretaría de Cultura y Turismo, Colección Fondo de autores huilenses, Neiva, 2007, 266 págs.

  20. Chemical composition of the essential oil of Moluccella spinosa L. (Lamiaceae) collected wild in Sicily and its activity on microorganisms affecting historical textiles.

    Science.gov (United States)

    Casiglia, Simona; Jemia, Mariem Ben; Riccobono, Luana; Bruno, Maurizio; Scandolera, Elia; Senatore, Felice

    2015-01-01

    In this study the chemical composition of the essential oil from aerial parts of Moluccella spinosa L. collected in Sicily was evaluated by GC and GC-MS. The main components of M. spinosa L. were α-pinene (26.6%), caryophyllene oxide (16.8%) and β-caryophyllene (8.6%). A comparison with other studied oils of genus Moluccella is made. Antibacterial and antifungal activities against some microorganisms infesting historical textiles were also determined.

  1. Mediterranean Aquaculture: Marine Fish Farming Development

    OpenAIRE

    Basurco, B

    2001-01-01

    in many parts of the world, aquaculture production in the Mediterranean has been expanding rapidly over recent years. Total aquaculture production in the region reached 1,266,959 t in 1999, which represents approximately 6% of the world aquaculture production (3% in 1995). Although Mediterranean aquaculture still focuses more on mollusc production (53.9%), the share of fish production is progressing constantly (46% in 1999, and 35% in 1995), parallel to global trends of world a...

  2. INTEGRAL observation of the Galactic transient Swift J174510.8-262411

    DEFF Research Database (Denmark)

    Vovk, I.; Ferrigno, C.; Bozzo, E.

    2012-01-01

    During the INTEGRAL observations in direction of IGR J17544-2619 and the Galactic bulge performed from 2012-09-16T01:15 to 2012-09-17 05:34 UTC, a bright new transient is detected at coordinates RA=266.29,Dec=-26.40 with a 0.6 arcmin, 90% c.l. confinement radius. The location of the INTEGRAL sour...

  3. A Geometrically Nonlinear Phase Field Theory of Brittle Fracture

    Science.gov (United States)

    2014-10-01

    tension. Int J Fract Mech 4:257–266 Voyiadjis G, Mozaffari N (2013) Nonlocal damage model using the phase field method: theory and applications. Int J... model of fracture. Computer simula- tions enable descriptions of fracture in brittle solids under complex loading conditions and for nonlinear and...Simple models based on the notion of theo- retical strength (Gilman1960;Clayton 2009, 2010) can provide insight into directionality of fracture

  4. Positive selection in the hemagglutinin-neuraminidase gene of Newcastle disease virus and its effect on vaccine efficacy

    Directory of Open Access Journals (Sweden)

    Hu Shunlin

    2011-03-01

    Full Text Available Abstract Background To investigate the relationship between the selective pressure and the sequence variation of the hemagglutinin-neuraminidase (HN protein, we performed the positive selection analysis by estimating the ratio of non-synonymous to synonymous substitutions with 132 complete HN gene sequences of Newcastle disease viruses (NDVs isolated in China. Results The PAML software applying a maximum likelihood method was used for the analysis and three sites (residues 266, 347 and 540 in the HN protein were identified as being under positive selection. Codon 347 was located exactly in a recognized antigenic determinant (residues 345-353 and codon 266 in a predicted linear B-cell epitope. Substitutions at codon 540 contributed to the N-linked glycosylation potential of residue 538. To further evaluate the effect of positively selected sites on the vaccine efficacy, we constructed two recombinant fowlpox viruses rFPV-JS6HN and rFPV-LaSHN, expressing the HN proteins from a genotype VII field isolate Go/JS6/05 (with A266, K347 and A540 and vaccine strain La Sota (with V266, E347 and T540, respectively. Two groups of SPF chickens, 18 each, were vaccinated with the two recombinant fowlpox viruses and challenged by Go/JS6/05 at 3 weeks post-immunization. The results showed that rFPV-JS6HN could elicit more effective immunity against the prevalent virus infection than rFPV-LaSHN in terms of reducing virus shedding. Conclusions The analysis of positively selected codons and their effect on the vaccine efficacy indicated that the selective pressure on the HN protein can induce antigenic variation, and new vaccine to control the current ND epidemics should be developed.

  5. Soluble and Electroactive Nickel Bis(dithiolene) Polymers Prepared Via Metal Complexation Polymerization

    Science.gov (United States)

    1990-04-17

    325, 957. (6) Vicente , R.: Ribas, J.; Cassoux, P.; Valade, L. Synth. Me. 1986, 13, 265. (7) Go;zfried, F.; Beck, W.: Lerf, A.; Sebald, A. Angew. Chcm...Bosseau, M.; Barrett, P. H.; Moraes , F.; Wudl, F.; Heeger, A. j. Macromolecules 1986, 19, 266. (12) Wang, F.; Reynolds, J. R. Macromolecules 1988, 2...Bowmaker, G. A.: Boyd, P. D. W.; Campbell, G. K. Izorg. Chem. 1983, 22. 1208. (26) Alvarez, S.; Vicente , R.; Hoffman, R. J. Am. Chem. Soc. 1985, 107

  6. Technical Ramifications of Inclusion of Toxins in the Chemical Weapons Convention (CWC), Supplement

    Science.gov (United States)

    1993-08-01

    UNCLASSIFIED) 2. Abraham, W.K., et al. "Airway Effects of Inhaled Bradykinin, Substance P, and Neurokinin A in Sheep." (U) (1991). J. Allergy Clin...Output of Vasoactive Intestinal Polypeptide in the Feline Colon." (U) (1991). Life Sci. 48:1037-1944. (UNCLASSIFIED) 17. Brown, R., et al...34Potent Vasoactive Properties of Endothelin 1 in Human Skin ." (U) (1991). J. Appl. Phys. 70:260-266. (UNCLASSIFIED) 27. Darlak, K., Benovitz, D.E

  7. Feasibility of SH2 Binding as a Prognostic and Diagnostic Indicator: Probing the Tyrosine Phosphorylation State in Breast Cancer by Src Homology 2 Domain Binding

    Science.gov (United States)

    2005-08-01

    binding preferences by peptide library screening . This proteomic approach permits the rapid and comprehensive analysis of global patterns of SH2...described above were determined by combinatorial phosphopeptide library screening [6,7,59,61.109,165,255----258], mutagenesis [259.266] or structural...mediating specific interactions. Phosphopeptide not yet been identified in these species [46.48]. Until three- library screening indicated the consensus

  8. Resilient Control and Intrusion Detection for SCADA Systems

    Science.gov (United States)

    2014-05-01

    failures or defects. Anomaly: refers to malicious and intrusive event plus abnormal yet non-intrusive behavior including (faulty and noisy /messy...detection: missed detection in the presence of a real intrusion. Note: Any large network is a very “ noisy ” environment even at the packet level. 3.0.4... Hotelling , pages 448–485, 1960. [266] J. Tukey. Exploratory Data Analysis. Addision-Wesley, Reading,MA, 1977. [267] A. Tversky and D. Kahneman. Loss

  9. Rh-Catalyzed Asymmetric Hydrogenation of a-Enol Ester Phosphonates with 1-Phenylethylamine-Derived Phosphine- Phosphoramidite Ligands

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    HU Juan, WANG Dao-yong, ZHENG Zhuo, HU Xiang-ping J. Mol. Catal. (China) 2012, 26(6), 487 ~492 Chiral phosphine-phosphoramidite ligand, ( So, S,, )-2b, was found to be highly efficient in the Rh-catalyzed asymmetric hydrogenation of various α-enol ester phosphonates, in which excellent enantioselectivities (up to 〉99% ee) and high catalyticactivity ( S/C up to 5000) were achieved.

  10. Experimental Demostration of Wavelength Tuning in High-Gain Harmonic Generation Free Electron Laser

    CERN Document Server

    Shaftan, Timur; Krinsky, Sam; Loos, Henrik; Murphy, James; Rakowsky, George; Rose, James; Sheehy, Brian; Skaritka, John; Wang, Xijie; Wu, Zilu; Yu Li Hua

    2004-01-01

    We present experimental results on tuning of the HGHG FEL output wavelength while holding the input seed wavelength constant. Using compression of the initially chirped beam in the HGHG dispersion section we have measured the wavelength shift of about 1% around the nominal value of 266 nm. The tuning range is expected to reach 3 % after the dispersive section upgrade at the DUV FEL. An optimized design based on this principle, using additional linac sections, would have the capability of providing full tunability.

  11. The Negations of Conjunctions, Conditionals, and Disjunctions

    Science.gov (United States)

    2014-06-03

    example, Beth and Piaget (1966, p. 181) wrote that given a hy pothesis of the form, if p then q, individuals should try to refute it by searching for...hypothesis testing (Beth & Piaget , 1966, p. 181), whereas other formal theorists take it to verge on the paradoxical (Rips, 1994, p. 125). The facts are...Cognition, 75, 237–266. Barsalou, L. W. (1999). Perceptual symbol systems. Behavioral and Brain Sciences, 22, 577–660. Beth, E. W., & Piaget , J. (1966

  12. Reproductive biology of the biofuel plant Jatropha curcas in its center of origin

    OpenAIRE

    2016-01-01

    In this work, we studied the main characteristics of flowering, reproductive system and diversity of pollinators for the biofuel plant Jatropha curcas (L.) in a site of tropical southeastern Mexico, within its center of origin. The plants were monoecious with inflorescences of unisexual flowers. The male flowers produced from 3062–5016 pollen grains (266–647 per anther). The plants produced fruits with both geitonogamy and xenogamy, although insect pollination significantly increased the numb...

  13. Congenital heart disease

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920654 Angiocardiography in double out-let right ventricle with emphasis on anato-mic types, diagnosis and differential dia-gnosis. LI Yiqun (李益群), et al. Dept Radiol,Cardiovasc Instit & Fuwai Hosp, CAMS, 100037.Chin J Radiol 1992; 26(6): 380-384. Based on the correlative study of angiocardic-graphy and surgical exploration in 52 cases with

  14. Poor Vitamin C Status Late in Pregnancy Is Associated with Increased Risk of Complications in Type 1 Diabetic Women: A Cross-Sectional Study

    DEFF Research Database (Denmark)

    Juhl, Bente; Lauszus, Finn Friis; Lykkesfeldt, Jens

    2017-01-01

    of 26.6 μmol/L, respectively, and the umbilical cord blood vitC level (mean (SD)): 101.0 μmol/L (16.6) versus 78.5 μmol/L (27.8), p = 0.02; n = 12/16), while no relation to birth weight or Apgar score was observed. Diabetic women with complications of pregnancy had significantly lower vitC levels...

  15. Stimulated Emission at 722.9 nm by Laser Photodissociation of PbI2 Vapor

    Institute of Scientific and Technical Information of China (English)

    MAN Bao-Yuan; ZHANG Jie; NI Pei-Gen; ZHANG Dao-Zhong

    2000-01-01

    The stimulated emission at 722.9nm is observed by a direct photodissociation of the PbI2 molecules with a 266nm pulse laser. The possible dissociation channels are discussed. Two-photon resonant photodissociation mechanism is used to explain the generation of the 722.9 nm emission. The emission is measured at different incident laser energy and heat-pipe temperature. The obtained experimental result is well supported by the photodissociation mechanism given by us.

  16. [Obstructive anuria. Thirty cases].

    Science.gov (United States)

    Bennani, S; Debbagh, A; Joual, A; el Mrini, M; Benjelloun, S

    1995-01-01

    The authors report 30 cases of obstructive anuria during the last fifteen years. The anuria was secondary to lithiasis in 60 per cent, in 26.6 per cent to pelvic cancer and in 13.4 per cent to retroperitoneal fibrosis. The diagnosis was facilitated by ultrasonography. Emergency treatment of obstructive anuria is based on urinary diversion by ureteral stent or by percutaneous nephrostomy under ultrasound control. Later the treatment depend of etiology.

  17. Impacts of Military Training and Land Management on Threatened and Endangered Species in the Southeastern Fall Line Sandhills Communities

    Science.gov (United States)

    2009-05-01

    Installations in the Southeastern United States (Martin et al. 2001), included determining the life history and habitat requirements of TES species...Mosses Lichens Carphephorus Liatris Shrubs Trees Vines Bare Ground Woody Debris Burn Only Burn + Shred Burn + Herbicide 1.59 0.42 2.66...climate, but locally regulated by the influence of disturbance and land-use histories . Sampled TES plant species had differential actual and

  18. The Battalion Decision Aid: A Kernel Decision Support System

    Science.gov (United States)

    1989-06-01

    RECON PLT E Co 1/33 INF (ITV) 4.1 MORTOR PLY B Co 1140 AR (MI) 1-2 Seo SPLT 8 Co 258 ADA (STINGER) C Co 1/40 AR ftl) 1-2 Sea 8PLT A Co 266 ADA ( VULCAN ...number) / TESIS CRAINW: JOBN R. VALUSEK Lt Col USAFASaTA L NOSSOR Of 6Pm11Ioy RESEARC ABSTRACT: SEE REVERSE SIDE. 20 DISTRIBUTION /AVAILABILITY OF

  19. Point Intercept and Surface Observation GPS (SOG): A Comparison of Survey Methods - Lake Gaston, NC/VA

    Science.gov (United States)

    2008-11-01

    coverage by hydrilla was greater than 50% (littoral zone approximately 5,000 acres, Madsen 2007). Scientific name Common name Exotic/native Whole lake...vegetation in the lake. Scientific name Common name Monospecific acres Total acres Native emergent Echinodorus cordifolius creeping burhead...0.001 0.001 Eleocharis macrostachya flatstem spikerush 0.002 0.002 E. quadrangulata squarestem spikerush 2.66 7.21 Hibiscus spp. mallow 0.06 0.27

  20. Ultra-deep pyrosequencing of partial surface protein genes from infectious Salmon Anaemia virus (ISAV suggest novel mechanisms involved in transition to virulence.

    Directory of Open Access Journals (Sweden)

    Turhan Markussen

    Full Text Available Uncultivable HPR0 strains of infectious salmon anaemia viruses (ISAVs infecting gills are non-virulent putative precursors of virulent ISAVs (vISAVs causing systemic disease in farmed Atlantic salmon (Salmo salar. The transition to virulence involves two molecular events, a deletion in the highly polymorphic region (HPR of the hemagglutinin-esterase (HE gene and a Q266→L266 substitution or insertion next to the putative cleavage site (R267 in the fusion protein (F. We have performed ultra-deep pyrosequencing (UDPS of these gene regions from healthy fish positive for HPR0 virus carrying full-length HPR sampled in a screening program, and a vISAV strain from an ISA outbreak at the same farming site three weeks later, and compared the mutant spectra. As the UDPS data shows the presence of both HE genotypes at both sampling times, and the outbreak strain was unlikely to be directly related to the HPR0 strain, this is the first report of a double infection with HPR0s and vISAVs. For F amplicon reads, mutation frequencies generating L266 codons in screening samples and Q266 codons in outbreak samples were not higher than at any random site. We suggest quasispecies heterogeneity as well as RNA structural properties are linked to transition to virulence. More specifically, a mechanism where selected single point mutations in the full-length HPR alter the RNA structure facilitating single- or sequential deletions in this region is proposed. The data provides stronger support for the deletion hypothesis, as opposed to recombination, as the responsible mechanism for generating the sequence deletions in HE.

  1. Osculating Relative Orbit Elements Resulting from Chief Eccentricity and J2 Perturbing Forces

    Science.gov (United States)

    2011-03-01

    eccentricity as a perturbation to the linearized HCW model using Hamiltonian mechanics . Another non-traditional solution is that of Vadali [25] and Sengupta...numerous partial deriva- tives and extensive use of Lagrangian mechanics will yield Lagrange’s planetary equa- tions, presented in Eq. 2.66 using... Hamiltonian Ap- proach to Eccentricity Perturbations,” AAS/AIAA Spacecraft Mechanics Meet- ing , Vol. 119, 2004, pp. 3075–3086. 25. Vadali, S. R., “An

  2. A Biophysico-Computational Perspective of Breast Cancer Pathogenesis and Treatment Response

    Science.gov (United States)

    2007-03-01

    2006). Mechanical control of tissue morphogenesis during embryological development. Int. J. Dev. Biol. 2–3, 255–266. Jacobson, M. D., Weil, M., and RaV...see appendix), we cannot rule 11 out the possibility that Rac-Pak-dependent modulation of Bad activity additionally contributes to the increased...cannot rule out the possibility that decreased Bad phosphorylation also contributes to Rac-Pak-dependent apoptosis resistance it seems more likely that

  3. Dicty_cDB: Contig-U14032-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ber of sequences better than 10.0: 0 Length of query: 158 Length of database: 95,242,211,685 Length adjustment: 22 Effective... length of query: 136 Effective length of database: 93,199,600,587 Effective search space: 12675145679832 Effective...gapped: 0 Length of query: 52 Length of database: 1,051,180,864 Length adjustment: 25 Effective... length of query: 27 Effective length of database: 970,266,889 Effective search space: 26197206003 Effective

  4. CERN, some astonishing ideas

    CERN Document Server

    Gourber, J P

    1982-01-01

    An account is given of the large (26.6 km) collision and storage ring of the CERN electron-positron collision accelerator under construction. This ring will incorporate a number of bending electromagnets, and the original and surprising design for them, the 'iron-concrete' cores are described, together with the technique for fabrication. A performance comparable with all-steel magnets but at considerably reduced cost is claimed.

  5. Review of Ordinary High Water Mark Indicators for Delineating Arid Streams in the Southwestern United States

    Science.gov (United States)

    2004-01-01

    Hydrogeology in the Arid and Semi-arid Areas of Africa, Proceedings of the Sahel Forum, Ouagadougou, 1989, p. 255–266. Nouh, M. (1990) Flood hydrograph... salinity levels may compound the effects of drought stress, leading to mortality in salt-intolerant species (Vandersande et al. 2001). At elevated... salinity levels in greenhouse experiments, rooted cuttings of T. ramosissima and P. sericea had higher water use efficiency than did P. fremontii, S

  6. 70+ Years of the Watson Integrals

    Science.gov (United States)

    Zucker, I. J.

    2011-11-01

    Watson (Q. J. Math. Oxford 10:266-276, 1939) published in 1939 the evaluation of three integrals submitted to him, which had arisen from a problem in physics (van Pepye in Physica 5:465-482, 1938). Over the years these integrals have continued to occur in other aspects of physics such as random walk problems. This article reviews these integrals and generalisations over the past 70 years.

  7. Status of Department of Defense Architecture Framework (DoDAF) Implementation within the Aeronautical Systems Center (ASC)

    Science.gov (United States)

    2007-11-02

    characterizes these complex, unprecedented systems” (26:6). Further, Howard Eisner offers the following in his book, Essentials of Project and Systems...definitions deal with architectures role in the design of the system. Howard Eisner, author of Essentials of Project and Systems Engineering Management...prescribed several views as beneficial to the program manager in acquisition strategy development. Further, as Zinn noted, with the Clinger-Cohen Act

  8. Cardioembolic stroke prompting diagnosis of LMNA-associated Emery-Dreifuss muscular dystrophy.

    Science.gov (United States)

    Redondo-Vergé, Luis; Yaou, Rabah Ben; Fernández-Recio, María; Dinca, Luminita; Richard, Pascale; Bonne, Gisèle

    2011-10-01

    The diagnosis of Emery-Dreifuss muscular dystrophy (EDMD) is suggested by the combination of musculoskeletal weakness and wasting, joint contractures, and cardiac disease. Herein we report a patient in whom an ischemic stroke prompted the diagnosis of EDMD. A mutation in the LMNA gene (c.266G>T, p.Arg89Leu) was found. It had been reported previously exclusively with isolated cardiac disease, thus reinforcing the high phenotypic heterogeneity of laminopathies.

  9. Propriedades térmicas e de pasta de misturas de fécula de mandioca e polpa cítrica

    OpenAIRE

    Magali Leonel; Luciana Bronzi de Souza; Martha Maria Mischan

    2011-01-01

    Instant mixtures are easy to prepare and frequently present functional appeals. A quality parameter for instant mixtures is their rheological behavior. This study aimed at evaluating the effects of extrusion parameters on the pasting properties of cassava (Manihot esculenta L.) starch and dehydrated orange (Citrus sinensis (L.) Osbeck) pulp mixtures. The variable parameters were moisture of mixtures (12.5 to 19%), barrel temperature (40 to 90ºC) and screw rotation (170 to 266 rpm). The extrud...

  10. Relationship Between Self-Efficacy and Symptoms of Anxiety, Depression, Worry and Social Avoidance in a Normal Sample of Students

    OpenAIRE

    Tahmassian, Karineh; Jalali Moghadam, Niloufar

    2011-01-01

    Objective: Self-efficacy beliefs determine how people feel, think, motivate themselves and behave. Regarding to similar findings it is supposed that concept of self efficacy has a general role on mental health. The present study focused on examining the relationships between self-efficacy and symptoms of depression, anxiety, worry and social avoidance in a large sample of normal students (n=549). Methods: The sample included of 266 female and 283 male high school students from schools of dist...

  11. Center of Excellence in Biotechnology (Fellowships)

    Science.gov (United States)

    1991-12-01

    Receptor-Mediated Activation of Ion Movements During Stimulus-Secretion Coupling in a Mast Cell Line. Soc of Gen Physiologists, September. Labrecque, G. F... Chloroplast Coupling Factor 1". J. Biol. Chem., 266, 4194- 4200. Willins, D.A., Ryan, C.W., Platko, J.V., and Calvo, J.M. (1991) "Characterization of Lrp...1991) "Fluorescence Resonance Energy Transfer Mapping of the Fourth of Six Nucleotide Binding Sites of Chloroplast Coupling Factor 1", Submitted to

  12. The Contingent Value of Organizational Integration

    Directory of Open Access Journals (Sweden)

    Virpi Turkulainen

    2013-08-01

    Full Text Available We elaborate the link between organizational design and effectiveness by examining organizational integration and performance in the context of modern manufacturing. Through careful contextualization and empirical analysis of 266 manufacturing organizations in three industries and nine countries, we uncover a joint effect of integration and complexity on organizational effectiveness. The results extend structural contingency theory, in particular the mechanisms that link organizational integration to organizational effectiveness. We conclude by discussing the continuing relevance of structural contingency theory.

  13. Transcriptional Regulation of Mouse Ribosomal RNA Synthesis by Pathways Involving Protein Kinase C, Calcium, Insulin and Serum

    Science.gov (United States)

    1992-05-08

    Arnheim , 1983). These enhancer regions share many of the same characteristics of polymerase II enhancers (Khoury and Grussl,1983). They enhance 6...1979) were kind gifts of Dr. Norman Arnheim . Plasmids pUC9, pUC19, and pUC18, T4 DNA ligase, all restriction enzymes and molecular weight markers were...H.E. Morgan, 1991. Phorbol Ester Stimulation of Protein Kinase C Activity and Ribosomal DNA Transcription, j. ;iol. Chem. 266:22003-22009. Arnheim , N

  14. Nociceptive Effects of Locally Treated Metoprolol

    Directory of Open Access Journals (Sweden)

    Nursima Cukadar

    2015-06-01

    Results: Metoprolol, an antagonist, significantly decreased the thermal latency and mechanical thresholds with dose and time dependent manner. However, dobutamine, an agonist, enhanced the latency and thresholds dose and time dependent. Conclusions: This results suggest that in contrast to dobutamine, locally treated metoprolol may cause hyperalgesic and allodynic actions. In addition, our results can demonstrate that peripheral beta-adrenergic receptors can play important roles in nociceptive process. [Cukurova Med J 2015; 40(2.000: 258-266

  15. Analisis Faktor-Faktor Yang Mempengaruhi Minat Mahasiswa Akuntansi Berkarir Sebagai Akuntan Publik (Studi Pada Mahasiswa Akuntansi Perguruan Tinggi Negeri Di Medan)

    OpenAIRE

    Herawati, Lily

    2016-01-01

    This research aims to analyze the influence of the motivation, gender, financial respect, profesional training, profesional recognation, sosial values, work environment, consideration of market employee, and personality against accounting student interest on career as a public accountant. The object of the research were accounting student at state of university in Medan as a research sample that taken by using purposive sampling technique. There were 266 accounting students partisipating as ...

  16. Særligt pesticidfølsomme lerområder

    DEFF Research Database (Denmark)

    Nilsson, Bertel; Iversen, Bo Vangsø; Nygaard, Erik;

    daværende amter til opgave at udpege de områder, som er særligt følsomme for bestemte typer af forurening samt at prioritere den indsats, der skal gennemføres i disse områder for at beskytte vandressourcen. Lovgrundlaget er L 56 26/6 1998 om ændring af lov om vandforsyning m.v., samt lov om miljø...

  17. Merged Sounding Value-Added Product

    Energy Technology Data Exchange (ETDEWEB)

    Troyan, D

    2010-03-03

    The Merged Sounding value-added product (VAP) uses a combination of observations from radiosonde soundings, the microwave radiometer (MWR), surface meteorological instruments, and European Centre for Medium-Range Weather Forecasts (ECMWF) model output with a sophisticated scaling/interpolation/smoothing scheme in order to define profiles of the atmospheric thermodynamic state at one-minute temporal intervals and a total of 266 altitude levels.

  18. American Higher Education in the Arabian Gulf-A Force for Liberalization

    Science.gov (United States)

    2010-06-01

    in Saudi Arabia, in descending order, are from India, Egypt, Pakistan, Philippines, Bangladesh , and Yemen.266 One of the main effects of the Gulf...countries, their share ranging from fifty-seven percent in Kuwait to eighty-six percent in Oman. In the late 1990s, India, Pakistan, Bangladesh , and Sri...making them open either only to men or only to women, but these are not in high-demand fields. Specifically, Bachelor of Science degrees in geology

  19. 75 FR 62923 - WRC-07 Table Clean-up Order

    Science.gov (United States)

    2010-10-13

    ... Table Frequency Nomenclature 1. In Radio Regulation No. 2.1 of the 2008 Edition of the ITU Radio Regulations, frequencies are expressed in kilohertz (kHz) up to and including ``3 000'' kHz (i.e., 3,000 kHz... limited to emission type 2K80J3E and as specified in Sec. 90.266. Also, although 20 frequencies...

  20. Low temperature magnetic structure of MnSe

    Indian Academy of Sciences (India)

    J B C Efrem D'sa; P A Bhobe; K R Priolkar; A Das; P S R Krishna; P R Sarode; R B Prabhu

    2004-08-01

    In this paper we report low temperature neutron diffraction studies on MnSe in order to understand the anomalous behaviour of their magnetic and transport properties. Our study indicates that at low temperatures MnSe has two coexisting crystal structures, high temperature NaCl and hexagonal NiAs. NiAs phase appears below 266 K and is antiferromagnetically ordered at all temperatures while the NaCl phase orders antiferromagnetically at 130 K.

  1. Fabrication of Three-Dimensional Imprint Lithography Templates by Colloidal Dispersions

    Science.gov (United States)

    2011-03-06

    Y. Khang, H. Kang, T.-I. Kim and H. H. Lee, Nano Lett. 2004, 25 4(4), 633. 18 C. Pina -Hernandez, P.-F. Fu and L. J. Guo, J. Vac. Sci. Technol. B...2008, 26(6), 2426. 19 C. Pina -Hernandez, L. J. Guo and P.-F. Fu, ACS Nano, 2010, 4(8), 4776. 30 20 A. Greco and A. Maffezzo li, J. Therm. Anal

  2. Target and resistance-related proteins of recombinant mutant human tumor necrosis factor-related apoptosis-inducing ligand on myeloma cell lines.

    Science.gov (United States)

    Jian, Yuan; Chen, Yuling; Geng, Chuanying; Liu, Nian; Yang, Guangzhong; Liu, Jinwei; Li, Xin; Deng, Haiteng; Chen, Wenming

    2016-06-01

    Recombinant mutant human tumor necrosis factor-related apoptosis-inducing ligand (rmhTRAIL) has become a potential therapeutic drug for multiple myeloma (MM). However, the exact targets and resistance mechanisms of rmhTRAIL on MM cells remain to be elucidated. The present study aimed to investigate the target and resistance-related proteins of rmhTRAIL on myeloma cell lines. A TRAIL-sensitive myeloma cell line, RPMI 8226, and a TRAIL-resistance one, U266, were chosen and the differentially expressed proteins between the two cell lines were analyzed prior and subsequent to rmhTRAIL administration by a liquid chromatography-tandem mass spectrometry method. The results showed that following TRAIL treatment, 6 apoptosis-related proteins, calpain small subunit 1 (CPNS1), peflin (PEF1), B-cell receptor-associated protein 31 (BAP31), apoptosis-associated speck-like protein containing CARD (ASC), BAG family molecular chaperone regulator 2 (BAG2) and chromobox protein homolog 3 (CBX3), were upregulated in RPMI 8226 cells while no change was identified in the U266 cells. Furthermore, small ubiquitin-related modifier 1 and several other ubiquitin proteasome pathway (UPP)-related proteins expressed higher levels in TRAIL-resistant cells U266 compared to the RPMI-8226 cells prior and subsequent to rmhTRAIL treatment. These results suggested that CPNS1, PEF1, BAP31, ASC, BAG2 and CBX3 were possibly target proteins of rmhTRAIL on RPMI 8226 cells, while UPP may have a vital role in mediating TRAIL-resistance in U266 cells.

  3. Accession Medical Standards Analysis and Research Activity (AMSARA), 2014 Annual Report

    Science.gov (United States)

    2016-02-02

    syndrome of childhood 1,266 67.1 942 70.3 324 58.0 Anxiety , dissociative and somatoform disorders 681 63.6 526 67.5 155 50.3 Asthma 1,100 49.9 885...Table 1.10: Physical demands rating by TAPAS physical conditioning dimension score quintile, women ...26 Table 1.13: Healthcare utilization for overuse injuries, Women .................................................. 27 Table

  4. Accession Medical Standards Analysis and Research Activity (AMSARA) 2014, Annual Report, and four Supplemental Applicants and Accessions Tables for: Army, Air Force, Marine, and Navy

    Science.gov (United States)

    2016-02-02

    76.6 63 63.5 Hyperkinetic syndrome of childhood 1,266 67.1 942 70.3 324 58.0 Anxiety , dissociative and somatoform disorders 681 63.6 526 67.5 155...20 Table 1.10: Physical demands rating by TAPAS physical conditioning dimension score quintile, women ...injuries, Men ....................................................... 26 Table 1.13: Healthcare utilization for overuse injuries, Women

  5. Fluorescence preselection of bioaerosol for single-particle mass spectrometry

    Science.gov (United States)

    Stowers, M. A.; van Wuijckhuijse, A. L.; Marijnissen, J. C. M.; Kientz, Ch. E.; Ciach, T.

    2006-11-01

    We have designed, constructed, and tested a system that preselects the biological fraction of airborne particles from the overall aerosol. The preselection is based on fluorescence emission excited by a continuous 266 nm laser beam. This beam is one of two cw beams used to measure the aerodynamic particle size of sampled particles. The intention in our system is that single particles, based on size and fluorescence emission, can be selected and further examined for chemical composition by mass spectrometry.

  6. Fluorescence preselection of bioaerosol for single-particle mass spectrometry

    OpenAIRE

    Stowers, M.A.; van Wuijckhuijse, A.L.; Marijnissen, J.C.M.; Kientz, C.E.; Ciach, T.

    2006-01-01

    We have designed, constructed, and tested a system that preselects the biological fraction of airborne particles from the overall aerosol. The preselection is based on fluorescence emission excited by a continuous 266 nm laser beam. This beam is one of two cw beams used to measure the aerodynamic particle size of sampled particles. The intention in our system is that single particles, based on size and fluorescence emission, can be selected and further examined for chemical composition by mas...

  7. 阴道镜联合液基薄层细胞学检测对宫颈癌前病变的诊断价值%Diagnostic value of colposcopy combined new thinprep pap test in cervical cytology precancerous lesions

    Institute of Scientific and Technical Information of China (English)

    王继红

    2011-01-01

    目的 探讨阴道镜联合液基薄层细胞学检测(TCT)在宫颈病变筛查中的诊断价值.方法 选取行宫颈细胞学检查患者1 266例,行阴道镜和液基薄层细胞学联合检查.结果 本组所检1 266例中异常者169例,宫颈病变检出率13.35%,异常者中宫颈上皮内病变及鳞癌共126例,占9.99%.宫颈上皮内病变发病率检测各年龄组之间差异无统计学意义(P>0.05).结论 阴道镜联合液基薄层细胞学检测是宫颈癌前病变可靠的早期临床诊断方法.%Objective To evaluate the new colposcopy combined cytology thinprep pap test(TCT) in cervical screening in the diagnosis of disease. Methods 1 266 patients detected by gynecologic cervical cytology were conducted on colposcopy and liquid-based thin-layer cytology of the Joint Inspection. Results 1 266 cases in which seized 169 cases of abnormal cervical lesion detection rate of 13. 35%,abnormalities in cervical squamous intraepithelial lesions and 126 cases,accounting for 9.99%. The incidence of cervical intraepithelial lesions detected no difference between age groups was statistically significant(P>0.05). Conclusion Thinprep cytology combined colposcopy cervical precancerous lesions was a reliable method for early diagnosis.

  8. Temperature measurement using ultraviolet laser absorption of carbon dioxide behind shock waves.

    Science.gov (United States)

    Oehlschlaeger, Matthew A; Davidson, David F; Jeffries, Jay B

    2005-11-01

    A diagnostic for microsecond time-resolved temperature measurements behind shock waves, using ultraviolet laser absorption of vibrationally hot carbon dioxide, is demonstrated. Continuous-wave laser radiation at 244 and 266 nm was employed to probe the spectrally smooth CO2 ultraviolet absorption, and an absorbance ratio technique was used to determine temperature. Measurements behind shock waves in both nonreacting and reacting (ignition) systems were made, and comparisons with isentropic and constant-volume calculations are reported.

  9. 0935+05 Supernova 1995D in NGC 2962

    Science.gov (United States)

    Waagen, Elizabeth O.

    1995-02-01

    Reiki Kushida of Yatsugatake South Base Observatory discovers 0935+05 Supernova 1995D in NGC 2962. Magnitude 14.0. Position RA 09h 40m 54.79s DEC +5° 08' 26.6" (2000). Nova AQL 95 confirmed spectroscopically "as a slow 'FE II'-class nova in its post-maximum phase of development. Requests continue to monitor 1436-63 Nova Cir 95.

  10. Preliminary Guidelines for Safe and Effective Use of Hot, High-Pressure Washers for Maintenance Cleaning of Army Vehicles.

    Science.gov (United States)

    1982-11-01

    275W0) (31005 (34 4501 PRESSURE, psi ( tiPo ) Figure A3. Impact versus pressure; 0 constant. 31 A00- -- - I =.0526 Q/r- Q = CONSTANT 16 15 (66.7)(57 149...Cosbined Fores Comand V6301 Sunny Point NOT 266t ATTr DAN-Ca- ATTW: EUSA-HIC-CFC/Engr ATTN: tAIN-CWO NARADO M. ATTN O DNA -P 071160 ATTN. DALN-CwP -SA

  11. Dicty_cDB: Contig-U14968-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available anella Adh gene for... 266 7e-72 AJ515987_1( AJ515987 |pid:none) Miscanthus transmorrisonensis part... 270 9...al protei... 221 3e-71 AJ515989_1( AJ515989 |pid:none) Miscanthus transmorrisonensis part... 268 3e-71 AJ515...scanthus sinensis var. sinensis ... 268 3e-71 AJ515994_1( AJ515994 |pid:none) Miscanthus transmorrisonensis

  12. EST Table: NM_001126233 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available NM_001126233 Tra2 10/09/29 60 %/266 aa ref|NP_001119705.1| transformer 2 isoform A ...[Bombyx mori] gb|AAT42220.2| transformer-2 protein A [Bombyx mori] 10/09/13 65 %/101 aa FBpp0236157|Dvira2-P...gi|189240798|ref|XP_968550.2| PREDICTED: similar to transformer-2 protein A [Tribolium castaneum] NM_001126237 ...

  13. Uji Resistensi Beberapa Kultivar Plasma Nutfah Karet (Hevea brasiliensis Muell Arg) Terhadap Penyakit Gugur Daun (Corynespora cassiicola (Berk. & Curt.) Wei) Di Lapangan

    OpenAIRE

    Tari Elvalianda

    2009-01-01

    Penelitian ini dilaksanakan di Pusat Penelitian Perkebunan Sungei Putih dari bulan September 2006 sampai bulan Maret 2007. Tujuan penelitian ini adalah untuk mendapatkan kultivar karet yang tahan terhadap penyakit gugur daun (Corynespora cassiicola). Penelitian menggunakan Rancangan Acak Kelompok ( RAK ) Faktorial dengan 60 perlakuan kombinasi dan 2 ulangan. Kultivar plasma nutfah yang digunakan adalah PN No. 262, PN No. 266, PN No. 386, PN No. 389, PN No. 398, PN No. 803...

  14. [Effect of several extracts derived from plants on the survival of larvae of Aedes fluviatilis (Lutz) (Diptera: Culicidae) in the laboratory].

    Science.gov (United States)

    Consoli, R A; Mendes, N M; Pereira, J P; Santos, B de S; Lamounier, M A

    1988-01-01

    The larvicidal properties of 34 plant extracts were tested against Aedes fluviatilis (Lutz) (Diptera: Culicidae) larvae, at 100, 10 and 1 ppm concentrations; 26.6% of the extracts enhanced larval mortality (alpha = 0.05) at 100 ppm (Anacardium occidentale, Agave americana, Allium sativum, Coriandrum sativum, Nerium oleander, Spatodea campanulata, Tibouchina scrobiculata and Vernonia salzmanni). Anacardic acid (A. occidentale) was effective at 10 ppm and A. sativum (crude extract) at 1 ppm.

  15. Building Partner Capabilities for Coalition Operations

    Science.gov (United States)

    2007-01-01

    Corporation, MG-563-A, 2007. http://www.rand.org/pubs/monographs/MG563/ Olson , Mancur , Logic of Collective Action, Cambridge, Mass.: Harvard...University Press, 1965. Olson , Mancur , and Richard Zeckhauser, “An Economic Theory of Alliances,” The Review of Economics and Statistics, Vol. 48, No. 3...applying rational actor assumptions to the study of security issues, see Schelling (1963). Also, see Olson and Zeckhauser (1966, pp. 266–279), and Sandler

  16. SEG international exposition and sixty-fourth annual meeting -- 1994 Technical program: Expanded abstracts with authors` biographies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    The papers presented at the meeting are arranged into the following sections: Borehole geophysics; Computing techniques; Development and production geophysics; Electromagnetics; Gravity and magnetics; Interpretation methods and case histories; Mining geophysics; Near-surface geophysics; Poster presentations; Seismic acquisition; Seismic inversion; Seismic lithology; Seismic modeling and migration; Seismic processing; and a workshop on Seismic data acquisition and processing in mountainous thrust areas. 266 papers have been processed separately for inclusion on the data base.

  17. Russian Political Warfare: Origin, Evolution, and Application

    Science.gov (United States)

    2015-06-01

    absolute states of being, but rather, exist on a continuum. This idea has been explored by a diverse group of thinkers: from Mao, “Politics is war...These measures played a role in the Christian Democrats emerging with an absolute parliamentary majority in the elections.266 Whether or not the...local news not covered in state-controlled domestic media as well as religion, science, sports, Western music and locally banned literature and music

  18. Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes

    OpenAIRE

    Halstead, Susan K.; Kalna, Gabriela; Islam, Mohammad B.; Jahan, Israt; Mohammad, Quazi D.; Bart C Jacobs; Endtz, Hubert P.; Islam, Zhahirul; Willison, Hugh J.

    2016-01-01

    Objective: To characterize the patterns of autoantibodies to glycolipid complexes in a large cohort of Guillain-Barré syndrome (GBS) and control samples collected in Bangladesh using a newly developed microarray technique.\\ud \\ud Methods: Twelve commonly studied glycolipids and lipids, plus their 66 possible heteromeric complexes, totaling 78 antigens, were applied to polyvinylidene fluoride–coated slides using a microarray printer. Arrays were probed with 266 GBS and 579 control sera (2 μL p...

  19. Microarray screening of Guillain-Barré syndrome sera for antibodies to glycolipid complexes

    OpenAIRE

    Halstead, Susan K.; Kalna, Gabriela; Islam, Mohammad B.; Jahan, Israt; Mohammad, Quazi D.; Bart C Jacobs; Endtz, Hubert P.; Islam, Zhahirul; Willison, Hugh J.

    2016-01-01

    Objective: To characterize the patterns of autoantibodies to glycolipid complexes in a large cohort of Guillain-Barré syndrome (GBS) and control samples collected in Bangladesh using a newly developed microarray technique. Methods: Twelve commonly studied glycolipids and lipids, plus their 66 possible heteromeric complexes, totaling 78 antigens, were applied to polyvinylidene fluoride–coated slides using a microarray printer. Arrays were probed with 266 GBS and 579 control sera (2 μL per seru...

  20. Microbiologic and Clinical Study of Acute Diarrhea in Children in Aswan, Egypt

    Science.gov (United States)

    1989-01-01

    other enteropathogens. Salmonella- and shigella-infected children tended to be cider (mean age 26.6 months) than other children with acute diarrhea...Aswan. Mothers of patients were not just aware of the benefits of ORT but were Lnowledgeable enough to request the-goveriment supplied-rehydration packets...and use them effectively. -others were, in fact, soc.knowledgeable about the benefits of ORT that many were unwilling to wait for their child to

  1. Development of Carbon Nanotube-Based Sensor to Monitor Crack Growth in Cracked Aluminum Structures Underneath Composite Patching

    Science.gov (United States)

    2014-06-01

    carbon nanotube/epoxy composites,” Carbon, vol. 44, no. 14, pp. 3022–3029, Nov. 2006. [15] I. D. Rosca and S. V. Hoa , “Highly conductive...nanotube- based sensor- A review,” IEEE Sensors Journal, vol. 7, no. 1-2, pp. 266–284, Jan.–Feb., 2007. [23] M. Nofar, S. V. Hoa and M. D. Pugh

  2. Domain Modeling: NP_009061.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_009061.1 chrX DSNR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCGT SITE) c1a1ga_ chrX/NP_009061.1.../NP_009061.1_holo_185-266.pdb psi-blast 189L,192C,194T,195I,196L,197K,198H,199T,200L,201N,20

  3. Domain Modeling: NP_005896.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available 32H,333P,334A,335T,373K,378R,385W,388E,389Y,390H,392Q,393D,394V 242Y,245N,250E,251T,264F,265T,266D,267P,273R...,275C,277G,278L,280S,282V,289E,290N,292R,293R,294H,297K,316S,369Y,382V,383K,384G,389Y

  4. Reconstruction of the Phanerozoic tectono-thermal history of central and southern Madagascar, based on fission track thermochronology

    OpenAIRE

    Emmel, Benjamin

    2004-01-01

    Titanite and apatite fission track (FT) thermochronology on 127 basement and 18 sedimentary rock samples from central and southern Madagascar record a complex cooling and denudation history since the Early Palaeozoic. Titanite FT analyses gave ages ranging between 483 Ma and 266 Ma. Apatite FT ages vary between 460 Ma and 79 Ma. Samples from Late Carboniferous to Jurassic sediments from the Morondava basin gave apatite FT ages ranging between 462 Ma and 184 Ma. FT data argues for reactivation...

  5. Disorder-specific cognitive profiles in major depressive disorder and generalized anxiety disorder

    OpenAIRE

    Hendriks, S.M.; Licht, C.M.M.; Spijker, J; Beekman, A T F; Hardeveld, F.; de Graaf, R.; Penninx, B.W.J.H.

    2014-01-01

    Background: This investigation examines differences in cognitive profiles in subjects with major depressive disorder (MDD) and generalized anxiety disorder (GAD). Methods: Data were used from subjects with current MDD (n = 655), GAD (n = 107) and comorbid MDD/GAD (n = 266) diagnosis from the Netherlands Study of Depression and Anxiety (NESDA). The Composite Interview Diagnostic Instrument was used to diagnose MDD and GAD. Cognitive profiles were measured using the Leiden Index of Depression S...

  6. A Theoretical Study of Addition Reactions of L4M(M = Rh, Ir) and L2M(M = Pd, Pt) to Li+@C60.

    Science.gov (United States)

    Yang, Ming-Chung; Sharma, Akhilesh Kumar; Sameera, W M Chamil; Morokuma, Keiji; Su, Ming-Der

    2017-03-16

    The addition reaction of M(Cl)(CO)(PPh3)2 (M = Rh, Ir) and M(PPh3)2 (M = Pd, Pt) fragments with X@C60 (X = 0, Li+) were characterized by density functional theory (DFT) and the artificial force-induced reaction (AFIR) method. The calculated free energy profiles suggested that the η2[6:6]-addition is the most favorable reaction, which is consistent with the experimental observations. In the presence of Li+ ion, the reaction is highly exothermic, leading to η2[6:6] product of L4IrLi+@C60. In contrast, an endothermic reaction was observed in the absence of a Li+ ion. The encapsulated Li+ ion can enhance the thermodynamic stability of the η2[6:6] product. The energy decomposition analysis showed that the interaction between metal fragment and X@C60 fragment is the key for the thermodynamic stability. Among the group IA and IIA metal cations, Be2+ encapsulation is the best candidate for the development of new fullerene-transition metal complexes, which will be useful for future potential applications such as solar cells, catalysts, and electronic devices.

  7. Multiple myeloma cell lines and primary tumors proteoma: protein biosynthesis and immune system as potential therapeutic targets

    Science.gov (United States)

    Mazzotti, Diego Robles; Evangelista, Adriane Feijó; Braga, Walter Moisés Tobias; de Lourdes Chauffaille, Maria; Leme, Adriana Franco Paes; Colleoni, Gisele Wally Braga

    2015-01-01

    Despite great advance in multiple myeloma (MM) treatment since 2000s, it is still an incurable disease and novel therapies are welcome. Therefore, the purpose of this study was to explore MM plasma cells' (MM-PC) proteome, in comparison with their normal counterparts (derived from palatine tonsils of normal donors, ND-PC), in order to find potential therapeutic targets expressed on the surface of these cells. We also aimed to evaluate the proteome of MM cell lines with different genetic alterations, to confirm findings obtained with primary tumor cells. Bone marrow (BM) samples from eight new cases of MM and palatine tonsils from seven unmatched controls were submitted to PC separation and, in addition to two MM cell lines (U266, RPMI-8226), were submitted to protein extraction for mass spectrometry analyses. A total of 81 proteins were differentially expressed between MM-PC and ND-PC - 72 upregulated and nine downregulated; U266 vs. RPMI 8226 cell lines presented 61 differentially expressed proteins - 51 upregulated and 10 downregulated. On primary tumors, bioinformatics analyses highlighted upregulation of protein biosynthesis machinery, as well as downregulation of immune response components, such as MHC class I and II, and complement receptors. We also provided comprehensive information about U266 and RPMI-8226 cell lines' proteome and could confirm some patients' findings. PMID:26807199

  8. Common glycoproteins expressing polylactosamine-type glycans on matched patient primary and metastatic melanoma cells show different glycan profiles.

    Science.gov (United States)

    Kinoshita, Mitsuhiro; Mitsui, Yosuke; Kakoi, Naotaka; Yamada, Keita; Hayakawa, Takao; Kakehi, Kazuaki

    2014-02-07

    Recently, we reported comparative analysis of glycoproteins which express cancer-specific N-glycans on various cancer cells and identified 24 glycoproteins having polylactosamine (polyLacNAc)-type N-glycans that are abundantly present in malignant cells [ Mitsui et al., J. Pharm. Biomed. Anal. 2012 , 70 , 718 - 726 ]. In the present study, we applied the technique to comparative studies on common glycoproteins present in the matched patient primary and metastatic melanoma cell lines. Metastatic melanoma cells (WM266-4) contained a large amount of polyLacNAc-type N-glycans in comparison with primary melanoma cells (WM115). To identify the glycoproteins expressing these N-glycans, glycopeptides having polyLacNAc-type N-glycans were captured by a Datura stramonium agglutinin (DSA)-immobilized agarose column. The captured glycopeptides were analyzed by LC/MS after removing N-glycans, and some glycoproteins such as basigin, lysosome-associated membrane protein-1 (LAMP-1), and chondroitin sulfate proteoglycan 4 (CSPG4) were identified in both WM115 and WM266-4 cells. The expression level of polyLacNAc of CSPG4 in WM266-4 cells was significantly higher than that in WM115 cells. In addition, sulfation patterns of chondroitin sulfate (CS) chains in CSPG4 showed dramatic changes between these cell lines. These data show that characteristic glycans attached to common proteins observed in different stages of cancer cells will be useful markers for determining degree of malignancies of tumor cells.

  9. Reliability of Czochralski-grown {beta}-BaB{sub 2}O{sub 4}(BBO) devices

    Energy Technology Data Exchange (ETDEWEB)

    Umezu, Nobuhiko; Fukui, Tatsuo; Okamoto, Tsutomu; Wada, Hiroyuki; Tatsuki, Kouichi; Kondo, Kenji; Kubota, Shigeo [Sony Corp., Tokyo (Japan)

    1998-03-01

    We have achieved more than 1000 hours-operation in 266 nm-continuous wave (CW), 100 mW-generation of all-solid-state-UV laser system using Czochralski (Cz)-grown {beta}-BaB{sub 2}O{sub 4}(BBO) crystal devices. Absorption of the Cz-grown crystal for e-ray at 266 nm was improved to 1%/cm, which is one-third lower than that of the crystal grown by top seeded solution growth (TSSG) method. Degradation rate of 266 nm generation, using 7 kHz repetition rate laser diode pumped Q switched Nd:YAG laser as a fundamental light source, was one order of magnitude lower than that of TSSG-crystal. Surface roughness of the crystal was better than 0.3 rms.-nm. HfO{sub 2} film with extremely high adhesion was deposited on the surfaces using reactive low voltage ion plating method. Our devices can be put to practical use in areas of photolithography, micro fabrication, material processing and ultra high density optical disk mastering. (author)

  10. The Naval Aviation Enterprise Type/Model/Series Team and Its Effect on AH-1W Readiness

    Science.gov (United States)

    2012-03-23

    Hrs PMCS % VMM-264 FC7 AHAX 1/1/2001 17 907 1.22 13.94 902.00 99.4% 5.00 0.6% 0.00 0.0% 0.00 0.0% 5.00 0.6% 0.00 0.0% 0.00 0.0% VMM-266 FCQ AHAX 1...0.0% 589.00 6.6% 688.00 7.7% 193.00 2.2% VMM-266 FCQ AHAX 2/1/2001 151 4032 6.00 25.17 3531.00 87.6% 170.00 4.2% 331.00 8.2% 0.00 0.0% 170.00 4.2...2.6% 0.00 0.0% 121.00 10.9% 5.00 0.4% 83.00 7.5% VMM-266 FCQ AHAX 3/1/2001 150 4464 6.00 25.00 3440.00 77.1% 321.00 7.2% 703.00 15.7% 0.00 0.0% 321.00

  11. Dissociation of carbon dioxide and creation of carbon particles and films at room temperature

    Energy Technology Data Exchange (ETDEWEB)

    Fukuda, Takahiro [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Maekawa, Toru [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Hasumura, Takashi [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Rantonen, Nyrki [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Ishii, Koji [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Nakajima, Yoshikata [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Hanajiri, Tatsuro [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Yoshida, Yoshikazu [Bio-Nano Electronics Research Centre, Toyo University, 2100 Kujirai, Kawagoe Saitama 350-8585 (Japan); Whitby, Raymond [School of Pharmacy and Biomolecular Sciences, University of Brighton, Cockroft Building, Lewes Road, Brighton BN2 4GJ (United Kingdom); Mikhalovsky, Sergey [School of Pharmacy and Biomolecular Sciences, University of Brighton, Cockroft Building, Lewes Road, Brighton BN2 4GJ (United Kingdom)

    2007-09-15

    As fluids approach their gas-liquid critical points, the physical properties such as the specific heat and compressibility diverge due to the formation of large molecular clusters. Incident light cannot penetrate near-critical fluids because of the large clusters, a phenomenon known as critical opalescence. In this paper, we irradiate near-critical carbon dioxide (ncCO{sub 2}), the critical temperature and pressure of which are 31.0{sup 0}C and 7.38 MPa, with a laser beam of 213, 266, 355 and 532 nm wavelength and show that CO{sub 2} is dissociated and particles are produced when the system is set so close to the critical point that critical opalescence occurs in the case of 213 and 266 nm wavelength, whereas no particles are produced when the temperature is made to deviate from the critical value. We also apply a dc electric field to ncCO{sub 2} during irradiation with a laser beam of 213 and 266 nm wavelength and find that particles are formed on both anode and cathode. As the intensity of the electric field increases, films are formed on the electrodes. Electron diffraction patterns and energy-dispersive x-ray, Auger electron, x-ray photoelectron and Raman spectroscopic analyses show that the particles and films are composed of amorphous carbon.

  12. Dissociation of carbon dioxide and creation of carbon particles and films at room temperature

    Science.gov (United States)

    Fukuda, Takahiro; Maekawa, Toru; Hasumura, Takashi; Rantonen, Nyrki; Ishii, Koji; Nakajima, Yoshikata; Hanajiri, Tatsuro; Yoshida, Yoshikazu; Whitby, Raymond; Mikhalovsky, Sergey

    2007-09-01

    As fluids approach their gas-liquid critical points, the physical properties such as the specific heat and compressibility diverge due to the formation of large molecular clusters. Incident light cannot penetrate near-critical fluids because of the large clusters, a phenomenon known as critical opalescence. In this paper, we irradiate near-critical carbon dioxide (ncCO2), the critical temperature and pressure of which are 31.0°C and 7.38 MPa, with a laser beam of 213, 266, 355 and 532 nm wavelength and show that CO2 is dissociated and particles are produced when the system is set so close to the critical point that critical opalescence occurs in the case of 213 and 266 nm wavelength, whereas no particles are produced when the temperature is made to deviate from the critical value. We also apply a dc electric field to ncCO2 during irradiation with a laser beam of 213 and 266 nm wavelength and find that particles are formed on both anode and cathode. As the intensity of the electric field increases, films are formed on the electrodes. Electron diffraction patterns and energy-dispersive x-ray, Auger electron, x-ray photoelectron and Raman spectroscopic analyses show that the particles and films are composed of amorphous carbon.

  13. The competition between alpha decay and spontaneous fission in odd-even and odd-odd nuclei in the range 99 \\leg Z \\leg 129

    CERN Document Server

    Santhosh, K P

    2015-01-01

    The predictions on the mode of decay of the odd-even and odd-odd isotopes of heavy and superheavy nuclei with Z = 99-129, in the range 228 \\leg A \\leg 336, have been done within the Coulomb and proximity potential model for deformed nuclei (CPPMDN). A comparison of our calculated alpha half lives with the values computed using other theoretical models shows good agreement with each other. An extensive study on the spontaneous fission half lives of all the isotopes under study has been performed to identify the long-lived isotopes in the mass region. The study reveals that the alpha decay half lives and the mode of decay of the isotopes with Z = 109, 111, 113, 115 and 117, evaluated using our formalisms, agrees well with the experimental observations. As our study on the odd-even and odd-odd isotopes of Z = 99-129 predicts that, the isotopes $^{238,240-254}$99, $^{244,246-258}$101, $^{248,250,252-260,262}$103, $^{254,256,258-262,264}$105, $^{258,260,262-264,266}$107, $^{262,264,266-274}$109, $^{266,268-279}$11...

  14. Resistless photochemical etching of a silicon wafer by UV laser with an H2O2 and HF aqueous solution

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A new resistless etching method has been developed for Silicon wafers. This new method uses an aqueous solution consisting of hydrogen peroxide (H2O2) and hydrogen fluoride (HF) as the activating etchants. A 193 nm ArF excimer laser and a 266 nm fourth harmonic generation Nd:YAG laser were used as the photon sources. Results showed that pattern etching has been achieved without any photoresist film. In the case of the 193 nm laser, the optimal etching appeared at a 1.3 H2O2/HF ratio, where an etch depth of 210 nm was achieved with a fluence of 29 mJ/cm2 and shot number of 10000. At the same conditions, the etch depth with H2O2 and HF solution was three times of that by using H2O and HF mixture. In the case of the 266 nm Nd:YAG laser, the optimal etching appeared at twice ratio of H2O2/HF, where the etch depth of 420 nm was achieved with a fluence of 12 mJ/cm2 and shot number of 30000. Results showed that the etch effect of the 266 nm Nd: YAG laser was more desirable than that of the 193 nm ArF excimer laser.``Keyords: UV laser, resistless photochemical etching, hydrogen peroxide (H2O2).

  15. Micrometric rods grown by nanosecond pulsed laser deposition of boron carbide

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Quintas, Ignacio; Oujja, Mohamed; Sanz, Mikel; Benitez-Cañete, Antonio [Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid (Spain); Chater, Richard J. [Imperial College London, South Kensington Campus, London SW7 2AZ (United Kingdom); Cañamares, Maria Vega [Instituto de Estructura de la Materia, CSIC, Serrano 119, 28006 Madrid (Spain); Marco, José F. [Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid (Spain); Castillejo, Marta, E-mail: marta.castllejo@iqfr.csic.es [Instituto de Química Física Rocasolano, CSIC, Serrano 119, 28006 Madrid (Spain)

    2015-02-15

    Highlights: • Micrometric rods obtained by ns pulsed laser deposition of boron carbide at 1064 and 266 nm. • At 1064 nm microrods display crystalline polyhedral shape with sharp edges and flat sides. • Microrods consist of a mixture of boron, boron oxide, boron carbide and aliphatic hydrocarbons. - Abstract: Micrometric size rods have been fabricated via pulsed laser deposition in vacuum from boron carbide targets using nanosecond pulses of 1064 and 266 nm and room temperature Si (1 0 0) substrates. Morphological, structural and chemical characterization of the microrods was made by applying scanning electron microscopy, focussed ion beam microscopy coupled to secondary ion mass spectrometry, X-ray diffraction, X-ray photoelectron spectroscopy and micro-Raman spectroscopy. Ablation at 1064 nm favours the formation of microrods with high aspect ratio, sharp edges and pyramidal tips, typically 10 μm long with a cross section of around 2 μm × 2 μm. Differently, at 266 nm the microrods are of smaller size and present a more globular aspect. The analyses of the microrods provide information about their crystalline nature and composition, based on a mixture which includes boron, boron oxide and boron carbide, and allows discussion of the wavelength dependent growth mechanisms involved.

  16. The Role of Myeloma Cells to Osteoclast Activation

    Directory of Open Access Journals (Sweden)

    Bahare Sadeghi

    2010-01-01

    Full Text Available Objective: Multiple myeloma (MM is a hematological malignancy characterized by osteolyticbone disease which is associated with severe bone pain and pathological bonefractures. The receptor activator of nuclear factor κB (RANK and receptor activator ofnuclear factor κB ligand (RANKL system has an important role in regulation of boneremodeling process. The aim of this study was to evaluate the expression of the RANK/RANKL molecules by the myeloma cells derived from patients and myeloma cell lineU-266.Materials and Methods: Myeloma cells derived from 7 myeloma patients and plasma cellleukemia were included into this study to evaluate the expression of the RANK/RANKLmolecules by the reverse transcriptions-polymerase chain reaction (RT-PCR method atthe mRNA level. As well as human myeloma cell line U266, U937, RPMI-8866 and Helawere used as control groups.Results: In this study we show the expression of RANK and its ligand at the mRNA levelin U-266 (myeloma cell line and plasma cells derived from patients by the RT-PCR technique.Conclusion: Our results demonstrate that expression of RANK and RANKL by plasmacells can contribute to induction of osteoclasts and plasma cell activation which elevatesbone resorption in myeloma patients.

  17. Medical Efforts and Injury Patterns of Military Hospital Patients Following the 2013 Lushan Earthquake in China: A Retrospective Study

    Directory of Open Access Journals (Sweden)

    Peng Kang

    2015-08-01

    Full Text Available The aim of this paper is to investigate medical efforts and injury profiles of victims of the Lushan earthquake admitted to three military hospitals. This study retrospectively investigated the clinical records of 266 admitted patients evacuated from the Lushan earthquake area. The 2005 version of the Abbreviated Injury Scale (AIS-2005 was used to identify the severity of each injury. Patient demographic data, complaints, diagnoses, injury types, prognosis, means of transportation, and cause of injury were all reviewed individually. The statistical analysis of the study was conducted primarily using descriptive statistics. Of the 266 patients, 213 (80.1% were admitted in the first two days. A total of 521 injury diagnoses were recorded in 266 patients. Earthquake-related injuries were primarily caused by buildings collapsing (38.4% and victims being struck by objects (33.8%; the most frequently injured anatomic sites were the lower extremities and pelvis (34.2% and surface area of the body (17.9%. Fracture (41.5% was the most frequent injury, followed by soft tissue injury (27.5%, but crush syndrome was relatively low (1.2% due to the special housing structures in the Lushan area. The most commonly used procedure was suture and dressings (33.7%, followed by open reduction and internal fixation (21.9%.The results of this study help formulate recommendations to improve future disaster relief and emergency planning in remote, isolated, and rural regions of developing countries.

  18. Stability-indicating validation of acitretin and isoacitretin in human plasma by LC-ESI-MS/MS bioanalytical method and its application to pharmacokinetic analysis.

    Science.gov (United States)

    Kumar, Ajay; Monif, Tausif; Khuroo, Arshad; Sasmal, Dinakar; Goswami, Dipanjan; Lahkar, Vijay Kumar

    2011-06-01

    LC- ESI- MS/MS simultaneous bioanalytical method was developed to determine acitretin and its metabolite isoacitretin in human plasma using acitretin-d3 used as the internal standard for both analytes. The compounds were extracted using protein precipitation coupled with liquid-liquid extraction with flash freezing technique. Negative mass transitions (m/z) of acitretin, isoacitretin and acitretin-d3 were detected in multiple reactions monitoring (MRM) mode at 325.4 → 266.3, 325.2 → 266.1 and 328.3 → 266.3, respectively, with a turbo ion spray interface. The chromatographic separation was achieved on an Ascentis-RP amide column (4.6 × 150 mm, 5 µm) with mobile phase delivered in isocratic mode. The method was validated over a concentration range of 1.025-753.217 ng/mL for acitretin and 0.394-289.234 ng/mL for isoacitretin with a limit of quantification of 1.025 and 0.394 ng/mL. The intra-day and inter-day precisions were below 8.1% for acitretin and below 13.8% for isoacitretin, while accuracy was within ±7.0 and ±10.6% respectively. For the first time, the best possible conditions for plasma stability of acitretin and isoacitretin are presented and discussed with application to clinical samples.

  19. Structural analysis of the promoter of tomato 1-aminocyclopropane-1-carboxylate synthase 6 gene(Le-ACS6)

    Institute of Scientific and Technical Information of China (English)

    LIN JingYu; FAN Rong; WAN XiaoRong; CHARNG Yeeyung; WANG NingNing

    2007-01-01

    Ethylene plays an important role in the regulation of many growth and developmental processes of higher plants. In tomato, Le-ACS6, a member of the ACC synthase multigene family involved in system 1 ethylene biosynthesis during fruit ripening, is subject to negative feedback regulation by ethylene. To identify the cis-elements that are responsible for the negative feedback control, we established an in vitro transient assay system employing particle bombardment on mature-green tomato fruit pericarp to examine the expression of a luciferase (LUC) reporter gene driven by a 5'-serially deleted Le-ACS6 promoter. The results localized putative cis-elements required for negative ethylene-response between -347 and -266 upstream from the translational start site ATG. Several lines of stable transformation of the Le-ACS6 promoter and GUS reporter fusion gene containing internal deletion from -347 to -266 were generated. The expression pattern of the GUS reporter showed that removal of the nucleotides from -347 to -266 completely eliminated the response of the Le-ACS6 promoter to exogenous ethylene.

  20. Publications of general practice research in China mainland 1993-2012:a bibliographic review%中国内地全科医学1993-2012年文献回顾分析

    Institute of Scientific and Technical Information of China (English)

    马超; 杜娟; 崔树起; 程艾军

    2014-01-01

    Objectives To review the publications of general practice research in China mainland from 1993 to 2012.Methods The literatures on general practice research published in China mainland from 1993 to 2012 were retrieved from the China Journal Full Text Databases , Wanfang Databases and PubMed . The publications were analyzed using the literature management software NoteExpress 2, Excelland SPSS 19.0.Results A total of 16 349 Chinese publications and 266 English publications of general practice research were collected .The amount of publications was gradually increasing during 1993 and 2012 and there was a sharp increase in the Chinese publications from 2008 to 2012 comparing with the previous years.The Chinese publications in China′s core journals accounted for 32.39%(5 295/16 349) of total of publications;and the English publications in SCI journals accounted for 96.62% ( 257/266 ) of total publications.The authors from community health service facilities accounted for 76.01%(12 427/16 349) of Chinese publications; while authors from research institutes and universities accounted for 61.65%(164/266) of the English publications .Results showed that 37.59% ( 6 145/16 349 ) and 37.12%( 6 069/16 349 ) of the Chinese publications were commentaries and descriptive studies , only 9.57%(1 565/16 349) were randomized controlled trials;52.63% (140/266) of the English publications were descriptive studies and 9.02% ( 24/266 ) were randomized controlled trials .60.75% ( 9 932/16 349 ) of the Chinese publications and 75.94% ( 202/266 ) of the English publications were focused on clinical topics.Conclusion Although the number of general practice publications has been increasing during 1993-2012, the quality of publications is still less satisfactory and need to be further improved .%目的:了解中国内地全科医学论文发表情况,分析存在问题并探讨对策。方法分别利用中国期刊全文数据库( CNKI)、万方数据库和PubMed对1993年1月1

  1. Efficient 2(nd) and 4(th) harmonic generation of a single-frequency, continuous-wave fiber amplifier.

    Science.gov (United States)

    Sudmeyer, Thomas; Imai, Yutaka; Masuda, Hisashi; Eguchi, Naoya; Saito, Masaki; Kubota, Shigeo

    2008-02-01

    We demonstrate efficient cavity-enhanced second and fourth harmonic generation of an air-cooled, continuous-wave (cw), single-frequency 1064 nm fiber-amplifier system. The second harmonic generator achieves up to 88% total external conversion efficiency, generating more than 20-W power at 532 nm wavelength in a diffraction-limited beam (M(2) crystal operated at 25 degrees C. The fourth harmonic generator is based on an AR-coated, Czochralski-grown beta-BaB(2)O(4) (BBO) crystal optimized for low loss and high damage threshold. Up to 12.2 W of 266-nm deep-UV (DUV) output is obtained using a 6-mm long critically phase-matched BBO operated at 40 degrees C. This power level is more than two times higher than previously reported for cw 266-nm generation. The total external conversion efficiency from the fundamental at 1064 nm to the fourth harmonic at 266 nm is >50%.

  2. Monoterpenos di-hidroxilados e hidróxi-nitrogenados 1,2 e 1,3 como ligantes quirais em reação de reformatsky assimétrica 1,2- and 1,3-dihydroxylated and hydroxynitrogenated monoterpenes as chiral ligands in the asymmetric reformatsky reaction

    Directory of Open Access Journals (Sweden)

    Carlos Magno R. Ribeiro

    2008-01-01

    Full Text Available This study describes the use of three (--alpha-pinene derivatives, one diol-1,2 [(--(1R, 2R, 3S, 5R-2,6,6-trimethylbicyclo[3.1.1]heptane-2,3-diol 4] and two piridine-hydroxy derivatives [(+-(1R,2S,3R,5S-2,6,6-trimethyl-3-(2-pyridinylmethylbicyclo[3.1.1]heptan-3-ol 7 and (--(1R,2S,3R,5S-2,6,6-trimethyl-3-[2-(2-pyridinyl ethyl]bicyclo[3.1.1]heptan-3-ol 8]; one diol-1,3 [(--(1S,2R,5S-2-(1-hydroxy-1-methylethyl-5-methylcyclohexanol 5] derived from (+-isopulegol 2 and one diol-1,3 [(+-(1R,2R,5R-2-(1-hydroxy-1-methylethyl-5-methylcyclohexanol 6] derived from (+-neo-isopulegol 3, as ligands in the asymmetric Reformatsky reaction. The best enantiomeric excess of beta-hydroxy ester obtained in the Reformatsky asymmetric reaction was 18% using ligand 6, and the chemical yield of the reactions was 65% on average.

  3. 1,2- and 1,3-dihydroxylated and hydroxynitrogenated monoterpenes as chiral ligands in the asymmetric reformatsky reaction; Monoterpenos di-hidroxilados e hidroxi-nitrogenados 1,2 e 1,3 como ligantes quirais em reacao de reformatsky assimetrica

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Carlos Magno R.; Morita, Cristina M.; Maia, Monica P. [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Inst. de Quimica. Dept. de Quimica Organica]. E-mail: gqocmrr@vm.uff.br

    2008-07-01

    This study describes the use of three (-)-{alpha}-pinene derivatives, one diol-1,2 [(-)- (1R, 2R, 3S, 5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-2,3-diol 4] and two pyridine-hydroxy derivatives [(+)-(1R,2S,3R,5S)-2,6,6- trimethyl-3-(2-pyridinylmethyl)bicyclo[3.1.1]heptane-3-ol 7 and (-)-(1R,2S,3R,5S)-2,6,6-trimethyl-3-[2-(2-pyridinyl) ethyl]bicyclo[3.1.1]heptane-3-ol 8]; one diol-1,3 [(-)-(1S,2R,5S)-2-(1-hydroxy-1-methylethyl)-5-methylcyclohexanol 5] derived from (+)-isopulegol 2 and one diol-1,3 [(+)-(1R,2R,5R)-2-(1-hydroxy-1-methylethyl)-5-methylcyclohexanol 6] derived from (+)-neoisopulegol 3, as ligands in the asymmetric Reformatsky reaction. The best enantiomeric excess of {beta}-hydroxy ester obtained in the Reformatsky asymmetric reaction was 18% using ligand 6, and the chemical yield of the reactions was 65% on average. (author)

  4. Biological activities of thermo-tolerant microbes from fermented rice bran as an alternative microbial feed additive.

    Science.gov (United States)

    Koh, J H; Suh, H J

    2009-06-01

    To evaluate the commercial potential of new microbial feed additive, Issatchenkia orientalis Y266 and Bacillus subtilis B266 from commercial fermented rice bran were tested for their tolerance or resistance to pH, bile, oxgall, and temperature. It was found that the strains grew very well up to pH 3.0 and resistant to relatively high concentrations of bile salt and oxgall. I. orientalis and B. subtilis are extremely tolerant in range of 70-90 degrees C in solid medium. B. subtilis B266 also has excellent tolerant property up to 90 degrees C in liquid medium. The health indexes (the microflora in the small intestines and the antibody titer to Newcastle disease virus) of chicks were significantly improved in the fermented rice bran with these strains (0.25% addition to diet) in comparison with the Avilamycin (20 mg/kg diet)-fed group (p fermented rice bran-fed group showed a better microbial flora in the small intestines. Accordingly, it would appear that the fermented rice bran with these strains may be a potential candidate for an alternative microbial feed additive.

  5. Trophic mode conversion and nitrogen deprivation of microalgae for high ammonium removal from synthetic wastewater.

    Science.gov (United States)

    Wang, Jinghan; Zhou, Wenguang; Yang, Haizhen; Wang, Feng; Ruan, Roger

    2015-11-01

    In this study, a well-controlled three-stage process was proposed for high ammonium removal from synthetic wastewater using selected promising microalgal strain UMN266. Three trophic modes (photoautotrophy, heterotrophy, and mixotrophy), two N sufficiency conditions (N sufficient and N deprived), two inoculum modes (photoautotrophic and heterotrophic), and different NH4(+)-N concentrations were compared to investigate the effect of trophic mode conversion and N deprivation on high NH4(+)-N removal by UMN266. Results showed that photoautotrophic inoculum with trophic mode conversion from heterotrophy to photoautotrophy and N deprivation in Stage 2 turned was the optimum plan for NH4(+)-N removal, and average removal rates were 12.4 and 19.1mg/L/d with initial NH4(+)-N of 80 and 160mg/L in Stage 3. Mechanism investigations based on algal biomass carbon (C) and N content, cellular composition, and starch content confirmed the above optimum plan and potential of UMN266 as bioethanol feedstock.

  6. Developments for transactinide chemistry experiments behind the gas-filled separator TASCA

    Energy Technology Data Exchange (ETDEWEB)

    Even, Julia

    2011-12-13

    synthesised carbonyl complexes were identified by nuclear decay spectroscopy. Some complexes were studied with isothermal chromatography or thermochromatography methods. The chromatograms were compared with Monte Carlo Simulations to determine the adsorption enthalpyrnon silicon dioxide and on gold. These simulations based on existing codes, that were modified for the different geometries of the chromatography channels. All observed adsorption enthalpies (on silcon oxide as well as on gold) are typical for physisorption. Additionally, the thermalstability of some of the carbonyl complexes was studied. This showed that at temperatures above 200 C therncomplexes start to decompose. It was demonstrated that carbonyl-complex chemistry is a suitable method to study rutherfordium, dubnium, seaborgium, bohrium, hassium, and meitnerium. Until now, only very simple, thermally stable compounds have been synthesized in the gas-phase chemistry of the transactindes. With the synthesis of transactinide-carbonyl complexes a new compound class would be discovered. Transactinide chemistry would reach the border between inorganic and metallorganic chemistry. Furthermore, the in-situ synthesised carbonyl complexes would allow nuclear spectroscopy studies under low background conditions making use of chemically prepared samples. [German] Die vorliegende Arbeit befasst sich mit der Entwicklung von Experimenten hinter dem gasgefuellten Separator TASCA (TransActinide Separator and Chemistry Apparatus) zur Studie des chemischen Verhaltens der Transactinide. Zum einen wurde die Moeglichkeit der elektrochemischen Abscheidung kurzlebiger Isotope der Elemente Ruthenium und Osmium auf Goldelektroden im Hinblick auf ein Experiment mit Hassium untersucht. Aus der Literatur ist bekannt, dass bei der elektrochemischen Abscheidung einzelner Atome das Abscheidepotential signifikant vom Nernst-Potential abweicht. Die Verschiebung des Potentials haengt von der Adsorptionsenthalpie des abzuscheidenden Elements

  7. NOD/SCID-GAMMA mice are an ideal strain to assess the efficacy of therapeutic agents used in the treatment of myeloma bone disease.

    Science.gov (United States)

    Lawson, Michelle A; Paton-Hough, Julia M; Evans, Holly R; Walker, Rebecca E; Harris, William; Ratnabalan, Dharshi; Snowden, John A; Chantry, Andrew D

    2015-01-01

    Animal models of multiple myeloma vary in terms of consistency of onset, degree of tumour burden and degree of myeloma bone disease. Here we describe five pre-clinical models of myeloma in NOD/SCID-GAMMA mice to specifically study the effects of therapeutic agents on myeloma bone disease. Groups of 7-8 week old female irradiated NOD/SCID-GAMMA mice were injected intravenously via the tail vein with either 1x106 JJN3, U266, XG-1 or OPM-2 human myeloma cell lines or patient-derived myeloma cells. At the first signs of morbidity in each tumour group all animals were sacrificed. Tumour load was measured by histological analysis, and bone disease was assessed by micro-CT and standard histomorphometric methods. Mice injected with JJN3, U266 or OPM-2 cells showed high tumour bone marrow infiltration of the long bones with low variability, resulting in osteolytic lesions. In contrast, mice injected with XG-1 or patient-derived myeloma cells showed lower tumour bone marrow infiltration and less bone disease with high variability. Injection of JJN3 cells into NOD/SCID-GAMMA mice resulted in an aggressive, short-term model of myeloma with mice exhibiting signs of morbidity 3 weeks later. Treating these mice with zoledronic acid at the time of tumour cell injection or once tumour was established prevented JJN3-induced bone disease but did not reduce tumour burden, whereas, carfilzomib treatment given once tumour was established significantly reduced tumour burden. Injection of U266, XG-1, OPM-2 and patient-derived myeloma cells resulted in less aggressive longer-term models of myeloma with mice exhibiting signs of morbidity 8 weeks later. Treating U266-induced disease with zoledronic acid prevented the formation of osteolytic lesions and trabecular bone loss as well as reducing tumour burden whereas, carfilzomib treatment only reduced tumour burden. In summary, JJN3, U266 or OPM-2 cells injected into NOD/SCID-GAMMA mice provide robust models to study anti-myeloma therapies

  8. NOD/SCID-GAMMA mice are an ideal strain to assess the efficacy of therapeutic agents used in the treatment of myeloma bone disease.

    Directory of Open Access Journals (Sweden)

    Michelle A Lawson

    Full Text Available Animal models of multiple myeloma vary in terms of consistency of onset, degree of tumour burden and degree of myeloma bone disease. Here we describe five pre-clinical models of myeloma in NOD/SCID-GAMMA mice to specifically study the effects of therapeutic agents on myeloma bone disease. Groups of 7-8 week old female irradiated NOD/SCID-GAMMA mice were injected intravenously via the tail vein with either 1x106 JJN3, U266, XG-1 or OPM-2 human myeloma cell lines or patient-derived myeloma cells. At the first signs of morbidity in each tumour group all animals were sacrificed. Tumour load was measured by histological analysis, and bone disease was assessed by micro-CT and standard histomorphometric methods. Mice injected with JJN3, U266 or OPM-2 cells showed high tumour bone marrow infiltration of the long bones with low variability, resulting in osteolytic lesions. In contrast, mice injected with XG-1 or patient-derived myeloma cells showed lower tumour bone marrow infiltration and less bone disease with high variability. Injection of JJN3 cells into NOD/SCID-GAMMA mice resulted in an aggressive, short-term model of myeloma with mice exhibiting signs of morbidity 3 weeks later. Treating these mice with zoledronic acid at the time of tumour cell injection or once tumour was established prevented JJN3-induced bone disease but did not reduce tumour burden, whereas, carfilzomib treatment given once tumour was established significantly reduced tumour burden. Injection of U266, XG-1, OPM-2 and patient-derived myeloma cells resulted in less aggressive longer-term models of myeloma with mice exhibiting signs of morbidity 8 weeks later. Treating U266-induced disease with zoledronic acid prevented the formation of osteolytic lesions and trabecular bone loss as well as reducing tumour burden whereas, carfilzomib treatment only reduced tumour burden. In summary, JJN3, U266 or OPM-2 cells injected into NOD/SCID-GAMMA mice provide robust models to study anti

  9. 锌掺杂对针状氧化铁的结构及电化学性能的影响%Effect of Doping Zinc Ion on Structure and Electrochemical Properties of Needle-like Iron Oxide Nanoparticles

    Institute of Scientific and Technical Information of China (English)

    吕慧; 蒋荣立; 周璐; 李艳芬

    2013-01-01

    采用微乳-超临界干燥法制备了Zn2+掺杂针状Zn034Fe2.66O4纳米晶.利用红外光谱仪、能谱仪、X射线衍射仪和透射电子显微镜对样品的晶体结构、化学组成、粒径和形貌进行表征.结果表明:产物为形貌规整的针状,长径比明显小于Fe3O4的.通过循环伏安、恒流充放电和交流阻抗等方法研究了Zn0.34Fe2.66O4电极的电化学性能,结果表明:在1mol/L H2SO4溶液中,在0~1.6V(vs饱和甘汞电极)电位范围内,Zn2+掺杂Zn0.34Fe2.66O4材料的电活性和循环稳定性、可逆性优于Fe3O4的.在1 A/g电流密度下,单电极比容量达1 116F/g,大电流充放电性能良好.%Zn0.34Fe2.66O4 nanociystallines were synthesized through a microemulsion-alcohol supercritical fluid drying technique. The structure, chemical composition, size and morphology of products were characterized by infrared spectroscopy, energy dispersive X-ray fluoresence spectrometry, X-ray diffraction and transmission electron microscopy. The results show that the as-prepared powder has a regularly needle-like morphology, and the aspect ratio of rod-like Zn0.34Fe2.66O4 microcrystallines is smaller than that of Fe3O4. The electrochemical properties of Zn0.34Fe2.66O4 electrode were investigated by using cyclic voltammetry, galvanostatic charge/discharge and electrochemical impedance spectrometry. It was indicated that Zn0.34Fe2.66O4 nanocrystallines exhibited better electrochemical performance and cycling stability in H2SO4 electrolyte of 1 mol/L in the potential range of 0-1.6 V (vs saturated calomel electrode). The specific capacitance of the material as a single electrode was 1 116F/g at the current density of 1 A/g. The sample had a better load discharge performance.

  10. Clinical Observation of Liver Damage in the Renal Allograft Recipients with Hepatitis B and Hepatitis C Viral Infection%乙、丙型肝炎病毒感染的肾移植受者肝损害临床观察

    Institute of Scientific and Technical Information of China (English)

    兰天飙; 任星峰; 彭隽

    2011-01-01

    Objective : To observe the clinical characteristics of liver damage in the renal allograft recipients with hepatitis B and hepatitis C Infection.Methods : A retrospective review of clinical manifestation was processed in 266 renal allograft recipients.65( 65/266 )cases with the infection of hepatitis B and hepatitis C virus( HBV and HCV ) hefore operation were divided into positive group, and 201( 201/266 ) cases without infection hefore operation were as negative control.All patients were treated with the similar immunosuppressive agents and liver protective medicine after operation.The liver function test, HBVDNA, HCVRNA and the concentration of CsA were monitored.The liver biopsy specimens from 28 patients with chronic hepatitis B and C were assessed.Results :The morbility and mortality of liver damage in the patients with HBV and HCV infection were significantly higher than those without infection.In the sole HBV infection, the degree of liver dysfunction was severer, the inflammatory activity index of liver tissue was higher,and 9 cases fibrosing cholestatic hepatitis( FCH ) were found.Conclusion : The incidence of liver damage in the renal allograft recipients with infection of HBV and HCV is higher after operation, the strict evaluation of liver function should be suhjected hefore operation.The liver damage of renal allograft patients with sole HBV infection should be paid more attention, and treated with protective FCH.%目的:观察乙、丙型肝炎病毒感染的肾移植受者术后肝损害的临床特点.方法:回顾性分析并跟踪观察了266例同种异体肾移植术受者的临床资料.65(65/266)例术前乙、丙肝炎病毒感染者作为阳性组,其中单一HBVM阳性者38例,单一抗HCV阳性者12例,HBVM/抗HCV双阳性15例;同期无病毒感染者201(201/266)例为阴性组.术后均采用三联免疫抑制方案及护肝药物治疗,同时监测肝功能、HBVDNA、HCVRNA及CsA药物浓度.28例术后乙、丙型肝炎受者作肝

  11. Multimodal emissions from Tb3+/Yb3+ co-doped lithium borate glass: Upconversion, downshifting and quantum cutting

    Science.gov (United States)

    Bahadur, A.; Yadav, R. S.; Yadav, R. V.; Rai, S. B.

    2017-02-01

    This paper reports the optical properties of Tb3+/Yb3+ co-doped lithium borate (LB) glass prepared by melt quench method. The absorption spectrum of the Yb3+ doped LB glass contains intense NIR band centered at 976 nm due to 2F7/2→2F5/2 transition. The emission spectra of the prepared glasses have been monitored on excitation with 266, 355 and 976 nm. The Yb3+ doped glass emits a broad NIR band centered at 976 nm whereas the Tb3+ doped glass gives off visible bands on excitations with 266 and 355 nm. When the Tb3+ and Yb3+ ions are co-doped together, the emission intensity in the visible region decreases whereas it increases in the NIR region significantly. The increase in the emission intensity in the NIR region is due to efficient cooperative energy transfer (CET) from Tb3+ to Yb3+ ions. The quantum cutting efficiency for Tb3+/Yb3+ co-doped glass has been calculated and compared for 266 and 355 nm excitations. The quantum cutting efficiency is larger for 355 nm excitation (137%). The Tb3+/Yb3+ co-doped LB glass also emits upconverted visible bands on excitation with 976 nm. The mechanisms involved in the energy transfer have been discussed using schematic energy level diagram. The Tb3+/Yb3+ co-doped LB glass may be used in the optical devices and in solar cell for solar spectral conversion and behaves as a multi-modal photo-luminescent material.

  12. Treatment with 5-Aza-2'-Deoxycytidine Induces Expression of NY-ESO-1 and Facilitates Cytotoxic T Lymphocyte-Mediated Tumor Cell Killing.

    Directory of Open Access Journals (Sweden)

    Agnes S Klar

    Full Text Available NY-ESO-1 belongs to the cancer/testis antigen (CTA family and represents an attractive target for cancer immunotherapy. Its expression is induced in a variety of solid tumors via DNA demethylation of the promoter of CpG islands. However, NY-ESO-1 expression is usually very low or absent in some tumors such as breast cancer or multiple myeloma. Therefore, we established an optimized in vitro treatment protocol for up-regulation of NY-ESO-1 expression by tumor cells using the hypomethylating agent 5-aza-2'-deoxycytidine (DAC.We demonstrated de novo induction of NY-ESO-1 in MCF7 breast cancer cells and significantly increased expression in U266 multiple myeloma cells. This effect was time- and dose-dependent with the highest expression of NY-ESO-1 mRNA achieved by the incubation of 10 μM DAC for 72 hours. NY-ESO-1 activation was also confirmed at the protein level as shown by Western blot, flow cytometry, and immunofluorescence staining. The detection and quantification of single NY-ESO-1 peptides presented at the tumor cell surface in the context of HLA-A*0201 molecules revealed an increase of 100% and 50% for MCF7 and U266 cells, respectively. Moreover, the enhanced expression of NY-ESO-1 derived peptides at the cell surface was accompanied by an increased specific lysis of MCF7 and U266 cells by HLA-A*0201/NY-ESO-1(157-165 peptide specific chimeric antigen receptor (CAR CD8+ T cells. In addition, the killing activity of CAR T cells correlated with the secretion of higher IFN-gamma levels.These results indicate that NY-ESO-1 directed immunotherapy with specific CAR T cells might benefit from concomitant DAC treatment.

  13. Optical properties of polydimethylsiloxane (PDMS) during nanosecond laser processing

    Science.gov (United States)

    Stankova, N. E.; Atanasov, P. A.; Nikov, Ru. G.; Nikov, R. G.; Nedyalkov, N. N.; Stoyanchov, T. R.; Fukata, N.; Kolev, K. N.; Valova, E. I.; Georgieva, J. S.; Armyanov, St. A.

    2016-06-01

    This article presents experimental investigations of effects of the process parameters on the medical grade polydimethylsiloxane (PDMS) elastomer processed by laser source with irradiation at UV (266 and 355 nm), VIS (532 nm) and NIR (1064 nm). Systematic experiments are done to characterize how the laser beam parameters (wavelength, fluence, and number of pulses) affect the optical properties and the chemical composition in the laser treated areas. Remarkable changes of the optical properties and the chemical composition are observed. Despite the low optical absorption of the native PDMS for UV, VIS and NIR wavelengths, successful laser treatment is accomplished due to the incubation process occurring below the polymer surface. With increasing of the fluence and the number of the pulses chemical transformations are revealed in the entire laser treated area and hence decreasing of the optical transmittance is observed. The incubation gets saturation after a certain number of pulses and the laser ablation of the material begins efficiently. At the UV and VIS wavelengths the number of the initial pulses, at which the optical transmittance begins to reduce, decreases from 16 up to 8 with increasing of the laser fluence up to 1.0, 2.5 and 10 J cm-2 for 266, 355 and 532 nm, respectively. In the case of 1064 nm the optical transmittance begins to reduce at 11th pulse incident at a fluence of 13 J cm-2 and the number of the pulses decreases to 8 when the fluence reaches value of 16 J cm-2. The threshold laser fluence needed to induce incubation process after certain number of pulses of 8 is different for every wavelength irradiation as the values increase from 1.0 for 266 nm up to 16 J cm-2 for 1064 nm. The incubation and the ablation processes occur in the PDMS elastomer material during its pulsed laser treatment are a complex function of the wavelength, fluence, number of pulses and the material properties as well.

  14. Microstructuring of fused silica by laser-induced backside wet etching using picosecond laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Ehrhardt, M. [Leibniz-Institute of Surface Modification, Permoserstr. 15, 04318 Leipzig (Germany); Raciukaitis, G.; Gecys, P. [Laboratory for Applied Research, Institute of Physics, Savanoriu Ave. 231, LT-02300 Vilnius (Lithuania); Zimmer, K., E-mail: martin.ehrhardt@iom-leipzig.de [Leibniz-Institute of Surface Modification, Permoserstr. 15, 04318 Leipzig (Germany)

    2010-09-15

    The laser-induced backside wet etching (LIBWE) is an advanced laser processing method used for structuring transparent materials. LIBWE with nanosecond laser pulses has been successfully demonstrated for various materials, e.g. oxides (fused silica, sapphire) or fluorides (CaF{sub 2}, MgF{sub 2}), and applied for the fabrication of microstructures. In the present study, LIBWE of fused silica with mode-locked picosecond (t{sub p} = 10 ps) lasers at UV wavelengths ({lambda}{sub 1} = 355 nm and {lambda}{sub 2} = 266 nm) using a (pyrene) toluene solution was demonstrated for the first time. The influence of the experimental parameters, such as laser fluence, pulse number, and absorbing liquid, on the etch rate and the resulting surface morphology were investigated. The etch rate grew linearly with the laser fluence in the low and in the high fluence range with different slopes. Incubation at low pulse numbers as well as a nearly constant etch rate after a specific pulse number for example were observed. Additionally, the etch rate depended on the absorbing liquid used; whereas the higher absorption of the admixture of pyrene in the used toluene enhances the etch rate and decreases the threshold fluence. With a {lambda}{sub 1} = 266 nm laser set-up, an exceptionally smooth surface in the etch pits was achieved. For both wavelengths ({lambda}{sub 1} = 266 nm and {lambda}{sub 2} = 355 nm), LIPSS (laser-induced periodic surface structures) formation was observed, especially at laser fluences near the thresholds of 170 and 120 mJ/cm{sup 2}, respectively.

  15. Biochemical Roles for Conserved Residues in the Bacterial Fatty Acid-binding Protein Family.

    Science.gov (United States)

    Broussard, Tyler C; Miller, Darcie J; Jackson, Pamela; Nourse, Amanda; White, Stephen W; Rock, Charles O

    2016-03-18

    Fatty acid kinase (Fak) is a ubiquitous Gram-positive bacterial enzyme consisting of an ATP-binding protein (FakA) that phosphorylates the fatty acid bound to FakB. In Staphylococcus aureus, Fak is a global regulator of virulence factor transcription and is essential for the activation of exogenous fatty acids for incorporation into phospholipids. The 1.2-Å x-ray structure of S. aureus FakB2, activity assays, solution studies, site-directed mutagenesis, and in vivo complementation were used to define the functions of the five conserved residues that define the FakB protein family (Pfam02645). The fatty acid tail is buried within the protein, and the exposed carboxyl group is bound by a Ser-93-fatty acid carboxyl-Thr-61-His-266 hydrogen bond network. The guanidinium of the invariant Arg-170 is positioned to potentially interact with a bound acylphosphate. The reduced thermal denaturation temperatures of the T61A, S93A, and H266A FakB2 mutants illustrate the importance of the hydrogen bond network in protein stability. The FakB2 T61A, S93A, and H266A mutants are 1000-fold less active in the Fak assay, and the R170A mutant is completely inactive. All FakB2 mutants form FakA(FakB2)2 complexes except FakB2(R202A), which is deficient in FakA binding. Allelic replacement shows that strains expressing FakB2 mutants are defective in fatty acid incorporation into phospholipids and virulence gene transcription. These conserved residues are likely to perform the same critical functions in all bacterial fatty acid-binding proteins.

  16. Pulsed UV laser light on Escherichia coli and Saccharomyces cerevisiae suspended in non-alcoholic beer

    Science.gov (United States)

    Hosseini, SM; Azar-Daryany, MK; Massudi, R; Elikaei, A

    2011-01-01

    Background The aim of this study was to investigate the effect of pulsed ultra-violet (UV) irradiation on inactivation of beer spoilage microorganisms. UV irradiation is nowadays cost effective enough to compete with traditional biological, physical, and chemical treatment technologies and has become an alternative to such methods. Material and Methods Photoinactivation effects of pulsed UV laser with the wavelengths of 355 and 266 nm, which inactivate typical prokaryotic (Escherichia coli) and eukaryotic (Saccharomyces cerevisiae) microorganisms, were examined with different doses and exposure times. Results A dose of 100 J/cm2 of the 355 nm pulsed UV laser was able to reduce about 1 to 2 log (88.75%) of E.coli with the population of 1.6×108 colony-forming units (CFU/ml), and 97% of 3.2×107, 3×106, 5.5×105, and 9×104 CFU/ml. In the case of 266 nm, more than 99% reduction in E. coli serial dilutions was inactivated, using 10 J/cm2 with exception of 7×104 CFU/ml which was not detected any bacterial growth using 5 J/cm2. In addition, 50, 40, and 20 J/cm2 energy were used successfully to inactivate S. cerevisiae at the populations of 5.4×106, 7×105, 5×104 and 4×103 CFU/ml, respectively. As a result, pulsed UV Laser with 266 nm was strong enough to inactivate a high titer of bacterial and yeast indicator standards suspended in non-alcoholic beer in comparison with 355nm doses. Conclusion Results indicate that pulsed UV technology, in principle, is an attractive alternative to conventional methods for the inactivation of indicator microorganisms and has potential in irradiation of unpasteurized beer. PMID:22347580

  17. Pulsed UV laser light on Escherichia coli and Saccharomyces cerevisiae suspended in non-alcoholic beer

    Directory of Open Access Journals (Sweden)

    A Elikaei

    2011-05-01

    Full Text Available Background: The aim of this study was to investigate the effect of pulsed ultra-violet (UV irradiation on inactivation of beer spoilage microorganisms. UV irradiation is nowadays cost effective enough to compete with traditional biological, physical, and chemical treatment technologies and has become an alternative to such methods."nMaterial and Methods: Photoinactivation effects of pulsed UV laser with the wavelengths of 355 and 266 nm, which inactivate typical prokaryotic (Escherichia coli and eukaryotic (Saccharomyces cerevisiae microorganisms, were examined with different doses and exposure times."nResults: A dose of 100 J/cm2 of the 355 nm pulsed UV laser was able to reduce about 1 to 2 log (88.75% of E.coli with the population of 1.6×108 colony-forming units (CFU/ml, and 97% of 3.2×107, 3×106, 5.5×105, and 9×104 CFU/ml. In the case of 266 nm, more than 99% reduction in E. coli serial dilutions was inactivated, using 10 J/cm2 with exception of 7×104 CFU/ml which was not detected any bacterial growth using 5 J/cm2. In addition, 50, 40, and 20 J/cm2 energy were used successfully to inactivate S. cerevisiae at the populations of 5.4×106, 7×105, 5×104 and 4×103 CFU/ml, respectively."nAs a result, pulsed UV Laser with 266 nm was strong enough to inactivate a high titer of bacterial and yeast indicator standards suspended in non-alcoholic beer in comparison with 355nm doses."nConclusion: Results indicate that pulsed UV technology, in principle, is an attractive alternative to conventional methods for the inactivation of indicator microorganisms and has potential in irradiation of unpasteurized beer.

  18. 广州市孕妇抑郁及社会支持状况的调查%A survey on depression of pregnant women in Guangzhou and social support

    Institute of Scientific and Technical Information of China (English)

    颜君; 刘悦新; 冯莹

    2011-01-01

    Objective To study the correlation between depressions in the pregnant women in Guangzhou and the social supports.Method 266 pregnant women in the obstetrical clinic of a comprehensive hospital in Guangzhou were chosen through convenient sampling for investigation of their demographic data.Edinburg Postnatal Depression Scale (EPDS) and social support.Results 17.3% of these pregnant women were scored more than 9 points in terms of EPDS.The depression was negatively related with social support, subjective and objective support as well as the utility of those aupports.Conclusion Petinent preventive meaaures are critical for preventinS the high-risk groups susceptible to depression from antepartum depression and improving the health of mother and infant.%目的 了解广州市孕妇的抑郁及社会支持状况,并分析探讨其两者间的相关性.方法 采用便利抽样法,对广州市某综合医院产科门诊接受产前保健服务的266例孕妇的一般情况、产后抑郁情况及社会支持状况进行调查.结果 266例孕妇中有抑郁症状的46例,占17.3%;孕妇的抑郁状况与社会支持、主观支持以及对支持的利用度存在负相关.结论 对产前出现抑郁症的高危人群,及时采取针对性的防治措施,对预防孕妇产前抑郁、改善母儿健康具有积极的意义.

  19. High frequencies of Y chromosome lineages characterized by E3b1, DYS19-11, DYS392-12 in Somali males

    DEFF Research Database (Denmark)

    Sanchez Sanchez, Juan Jose; Hallenberg, Charlotte; Børsting, Claus;

    2005-01-01

    f2) (27.1%), R1b3*(xR1b3d, R1b3f) (20.3%), E3b3 and R1a1*(xR1a1b) (both 11.9%). In Iraqis, 12 haplogroups were identified including J2*(xJ2f2) (29.7%) and J*(xJ2) (26.6%). The data suggest that the male Somali population is a branch of the East African population - closely related to the Oromos...

  20. Some Results on Sprout

    DEFF Research Database (Denmark)

    Banik, Subhadeep

    2015-01-01

    Sprout is a lightweight stream cipher proposed by Armknecht and Mikhalev at FSE 2015. It has a Grain-like structure with two state Registers of size 40 bits each, which is exactly half the state size of Grain v1. In spite of this, the cipher does not appear to lose in security against generic Time...... a simple key recovery attack that takes time equivalent to 266.7 encryptions with negligible memory requirement. This although is not the best attack reported against this cipher in termncryptions with negligible memory requirement. This although is not the best attack reported against this cipher in terms...