WorldWideScience

Sample records for blufensin1 negatively impacts

  1. The positive impact of negative role models

    OpenAIRE

    Al Khalidi, Marwa; Barton, John,; Gentile, Niko; Gosztonyi, Susanne; Ronchi, Enrico

    2015-01-01

    The attitude of teachers towards students can vary substantially in relation to different factors, such as educational background, pedagogical training, teaching methods, etc. In this paper, we explore the impact of negative role-models on future teaching. In particular, past experiences of teachers as students as well as the contextual influence of other teachers on their future teaching has been explored. The scope of this paper is to assess the possible impact that negative role-models may...

  2. Exploring Impact: Negative Effects of Social Networks

    OpenAIRE

    Egbert, Henrik; Sedlarski, Teodor

    2011-01-01

    he sociological literature on social networks emphasizes by and large positive network effects. Negative effects of such networks are discussed rather rarely. This paper tackles negative effects by applying economic theory, particularly neoclassical theory, new institutional theory and the results from experimental economics to the concept of social networks. In the paper it is assumed that social networks are exclusive and since exclusiveness affects the allocation of resources, negative ext...

  3. Positive and Negative Impacts of Renewable Energy Sources

    OpenAIRE

    Vezmar, Stanislav; Spajić, Anton; Topić, Danijel; Šljivac, Damir; JOZSA, Lajos

    2014-01-01

    In this paper, positive and negative impacts of renewable energy sources are presented. Impacts of solar power, biomass power, fuel cells, hydro power, wind power and geothermal power are described. Ecological, social and political impacts of different renewable energy sources are described. Impacts of power plants using different renewable energy sources on the power grid are also described.

  4. Impact of Negative Sequence Current Injection by Wind Power Plants

    DEFF Research Database (Denmark)

    Chaudhary, Sanjay; Göksu, Ömer; Teodorescu, Remus;

    2013-01-01

    This paper presents an analysis of the impact from negative sequence current injection by wind power plants in power systems under steady-state and short-term unbalanced conditions, including faults. The separate positive and negative sequence current control capability of the grid-side converters...

  5. Negative Impact of HRM Complementarity on Knowledge Transfer in MNCs

    OpenAIRE

    Minbaeva, Dana B.

    2005-01-01

    This paper explores reasons for negative complementarity among HRM practices. It is built upon the premise that there are certain HRM practices influencing extrinsic and intrinsic motivation of knowledge receivers. If those HRM practices are applied in a complementary way, their impact on knowledge-related outcomes will result in crowding effect of extrinsic and intrinsic motivation and be negative. Hypotheses derived from these arguments are tested on the data from 92 subsidia...

  6. The Impact of Negative Publicity on Celebrity Ad Endorsements

    OpenAIRE

    Thwaites, Des; Lowe, Ben; Monkhouse, Lien L.; Bradley R Barnes

    2012-01-01

    The article reports on an experiment to test the impact of negative publicity on celebrity ad endorsements. The extent to which negativity influences attitudes toward a celebrity, and to what degree this influences consumers of high–low involvement and image-related products is examined. Three hypothetical incidents relating to an extramarital affair, a drink-driving incident, and criticism of the professional integrity for three different celebrities (a television sitcom and film star, a tel...

  7. Negative Impact of HRM Complementarity on Knowledge Transfer in MNCs

    DEFF Research Database (Denmark)

    Minbaeva, Dana

    2005-01-01

    This paper explores reasons for negative complementarity among HRM practices. It isbuilt upon the premise that there are certain HRM practices influencing extrinsic andintrinsic motivation of knowledge receivers. If those HRM practices are applied in acomplementary way, their impact on knowledge......-related outcomes will result incrowding effect of extrinsic and intrinsic motivation and be negative. Hypothesesderived from these arguments are tested on the data from 92 subsidiaries of Danishmultinational corporations located in 11 countries.Extrinsic/intrinsic motivation, HRM practices, knowledge transfer...

  8. Negative-Margin Criterion for Impact-Response Prediction

    Science.gov (United States)

    Anderson, Denton

    2006-01-01

    Some space missions require a nuclear-power source to generate electrical power to meet mission objectives. At present, the nuclear-power source is an assembly of modular heat sources called the general purpose heat source (GPHS) modules. Each module comprises graphite shells designed to protect iridium-alloy clads which serve as the primary containment shells for the radioactive, heat-producing material. In the course of launching the space vehicle to perform its mission the nuclear heat source may be exposed to severe accident environments. One particular environment is a primary impact event where individual GPHS modules impact hard surfaces at speeds in the range of 50 meters per second or more. Tests have shown that some clads may be breached in particularly severe impacts and release a small fraction of their contents. This paper presents an empirical model for predicting essential ingredients for assessing the risk associated with primary impact events. The ingredients include: clad failure probability, release fraction of clad contents, characterization of the released material in terms of particle-size distribution and a means to estimate uncertainty in the prediction process. The empirical model focuses on the deformation of the clads and their capability to withstand deformation without breaching, measured by ductility. The basic criterion used to estimate all ingredients is called ``negative margin''. The procedure for estimating risk factors entails calculation of clad distortion by, e.g. hydrocode simulation, and high-strain-rate ductility of the iridium alloy. Negative margin is a linear combination of distortion and ductility. Regression equations derived from test data are used to calculate the clad failure probability and the fractional activity release as functions of negative margin. The mass-based particle-size distribution is calculated as a function of release fraction. Cumulative uncertainty in this computing process is evaluated using

  9. Predator cannibalism can intensify negative impacts on heterospecific prey.

    Science.gov (United States)

    Takatsu, Kunio; Kishida, Osamu

    2015-07-01

    of hatching can strengthen predatory effects on heterospecific prey and can have impacts on various, traits of both predator and prey. Because animals commonly broaden their diet as they grow, such negative impacts of predator cannibalism on the heterospecific prey may be common in interactions between predators and prey species of similar size. PMID:26378311

  10. NEUTRALIZATION OF HERBICIDE NEGATIVE IMPACT ON SUGAR BEET WITH BIOSTIMULATORS

    Directory of Open Access Journals (Sweden)

    Nazarenko D. Y.

    2013-10-01

    Full Text Available Most modern chemicals designed to protect crop also actually cause negative effects on the protected plants mostly due to side effects and/or not following the application procedures correctly. It is possible to neutralize the negative effects of herbicides they have on cultivated plants with precise use of immunostimulants which will increase the plants' natural immunity against the negative effects of biotic and abiotic environmental factors

  11. Prognostic impact of anticardiolipin antibodies in women with recurrent miscarriage negative for the lupus anticoagulant

    DEFF Research Database (Denmark)

    Nielsen, Henriette Svarre; Christiansen, Ole Bjarne

    2005-01-01

    BACKGROUND: Anticardiolipin antibodies (ACA) are found with increased prevalence in women with unexplained recurrent miscarriage (RM) but their impact on future pregnancy outcome in lupus anticoagulant (LAC) negative patients needs better quantification. METHODS: The impact of a repeatedly positive...

  12. Negative and positive impact of internet addiction on young adults: empericial study in Malaysia

    OpenAIRE

    Syed Shah Alam; Nik Mohd Hazrul Nik Hashim; Maisarah Ahmad; Che Aniza Che Wel; Sallehuddin Mohd Nor; Nor Asiah Omar

    2014-01-01

    Purpose: The purpose of this study is to explore and identify the impact of Internet addictions on young adults in Malaysia. There are six impacts identified, of which five are negative impacts and one is a positive impact. Design/methodology/approach: This study comprised a sample of 200 young adults in Malaysia. A cross-sectional research design was used to examine the impact of Internet addiction. Data were gathered based on personal administered questionnaires. Findings: Mann-Whitney U te...

  13. Invasive Asian Earthworms Negatively Impact Keystone Terrestrial Salamanders

    Science.gov (United States)

    Ziemba, Julie L.

    2016-01-01

    Asian pheretimoid earthworms (e.g. Amynthas and Metaphire spp.) are invading North American forests and consuming the vital detrital layer that forest floor biota [including the keystone species Plethodon cinereus (Eastern Red-backed Salamander)], rely on for protection, food, and habitat. Plethodon cinereus population declines have been associated with leaf litter loss following the invasion of several exotic earthworm species, but there have been few studies on the specific interactions between pheretimoid earthworms and P. cinereus. Since some species of large and active pheretimoids spatially overlap with salamanders beneath natural cover objects and in detritus, they may distinctively compound the negative consequences of earthworm-mediated resource degradation by physically disturbing important salamander activities (foraging, mating, and egg brooding). We predicted that earthworms would exclude salamanders from high quality microhabitat, reduce foraging efficiency, and negatively affect salamander fitness. In laboratory trials, salamanders used lower quality microhabitat and consumed fewer flies in the presence of earthworms. In a natural field experiment, conducted on salamander populations from “non-invaded” and “pheretimoid invaded” sites in Ohio, salamanders and earthworms shared cover objects ~60% less than expected. Earthworm abundance was negatively associated with juvenile and male salamander abundance, but had no relationship with female salamander abundance. There was no effect of pheretimoid invasion on salamander body condition. Juvenile and non-resident male salamanders do not hold stable territories centered beneath cover objects such as rocks or logs, which results in reduced access to prey, greater risk of desiccation, and dispersal pressure. Habitat degradation and physical exclusion of salamanders from cover objects may hinder juvenile and male salamander performance, ultimately reducing recruitment and salamander abundance

  14. Negative impact of asthma on patients in different age groups

    Directory of Open Access Journals (Sweden)

    Marcela Batan Alith

    2015-02-01

    Full Text Available Objective: To evaluate the impact of asthma on patients in Brazil, by age group (12-17 years, 18-40 years, and ≥ 41 years. Methods: From a survey conducted in Latin America in 2011, we obtained data on 400 patients diagnosed with asthma and residing in one of four Brazilian state capitals (São Paulo, Rio de Janeiro, Curitiba, and Salvador. The data had been collected using a standardized questionnaire in face-to-face interviews. For the patients who were minors, the parents/guardians had completed the questionnaire. The questions addressed asthma control, number of hospitalizations, number of emergency room visits, and school/work absenteeism, as well as the impact of asthma on the quality of life, sleep, and leisure. We stratified the data by the selected age groups. Results: The proportions of patients who responded in the affirmative to the following questions were significantly higher in the 12- to 17-year age group than in the other two groups: "Have you had at least one episode of severe asthma that prevented you from playing/exercising in the last 12 months?" (p = 0.012; "Have you been absent from school/work in the last 12 months?" (p < 0.001; "Have you discontinued your asthma relief or control medication in the last 12 months?" (p = 0.008. In addition, 30.2% of the patients in the 12- to 17-year age group reported that normal physical exertion was very limiting (p = 0.010 vs. the other groups, whereas 14% of the patients in the ≥ 41-year age group described social activities as very limiting (p = 0.011 vs. the other groups. Conclusions: In this sample, asthma had a greater impact on the patients between 12 and 17 years of age, which might be attributable to poor treatment compliance.

  15. The negative impact of organizational cynicism on physicians and nurses.

    Science.gov (United States)

    Volpe, Rebecca L; Mohammed, Susan; Hopkins, Margaret; Shapiro, Daniel; Dellasega, Cheryl

    2014-01-01

    Despite the potentially severe consequences that might result, there is a paucity of research on organizational cynicism within US health care providers. In response, this study investigated the effect of cynicism on organizational commitment, job satisfaction, and interest in leaving the hospital for another job in a sample of 205 physicians and 842 nurses. Three types of cynicism were investigated: trait (dispositional), global (directed toward the hospital), and local (directed toward a specific unit or department). Findings indicate that all 3 types of cynicism were negatively related to affective organizational commitment and job satisfaction, but positively related to interest in leaving. In both nurse and physician samples, cynicism explained about half of the variance in job satisfaction and affective commitment, which is the type of commitment managers are most eager to promote. Cynicism accounted for about a quarter and a third of the variance in interest in leaving the hospital for nurses and physicians, respectively. Trait, global, and local cynicism each accounted for unique variance in affective commitment, job satisfaction, and interest in leaving, with global cynicism exerting the largest influence on each outcome. The implications for managers are that activities aimed at decreasing organizational cynicism are likely to increase affective organizational commitment, job satisfaction, and organizational tenure. PMID:25350015

  16. Doing good buffers against feeling bad : prosocial impact compensates for negative task and self-evaluations

    OpenAIRE

    Grant, Adam M.; Sonnentag, Sabine

    2010-01-01

    Although evidence suggests that negative task and self-evaluations are associated with emotional exhaustion, little research has examined factors that buffer against these affects. We propose that perceived prosocial impact, the experience of helping others, compensates for negative task and self-evaluations by focusing attention on positive outcomes for others. In Study 1, perceived prosocial impact attenuated the associations of low intrinsic motivation and core self-evaluations with emotio...

  17. The Impact of Early Powered Mobility on Parental Stress, Negative Emotions, and Family Social Interactions

    Science.gov (United States)

    Tefft, Donita; Guerette, Paula; Furumasu, Jan

    2011-01-01

    Powered mobility has been found to have positive effects on young children with severe physical disabilities, but the impact on the family has been less well documented. We evaluated the impact of early powered mobility on parental stress, negative emotions, perceived social interactions, and parental satisfaction with wheelchair characteristics…

  18. Policy instruments to limit negative environmental impacts from increased international transport: An economic perspective

    OpenAIRE

    Van Dender, Kurt; Crist, Philippe

    2009-01-01

    Transport activities have adverse environmental and health impacts, of which local and regional air pollution, climate change, and noise impacts are the most important. This paper is a non-comprehensive overview of existing and potential policies to deal with these negative impacts, with a focus on “international transport”. We define “international transport” as those transport activities that are mainly derived from the globalization of economic activity, not as cross-border transport flows...

  19. Precipitations in the II region Antofagasta-Chile and their negative impacts

    International Nuclear Information System (INIS)

    The research has the purpose to acknowledge a diagnosis in relation to rainfalls motivated by the action of a frontal system and its negative impacts in the second Region-Antofagasta taken place on Tuesday 18 of June In 1991. The study looks at the synoptic situation that prevails in the Region, historical rainfalls period 1904-1991, floods caused by the effect of rain, the atmospheric situation that has affected the region on days June 17 and 18, lessons, education and propositions, in order to diminish in the future the negative impacts, human danger, technology-housing-located in the zones of high risks

  20. New Sails for the Recruitment, Retention, and Learning Ship: Repairing the Negative Impacts of Enrollment Management

    Science.gov (United States)

    Humphrey, Keith

    2008-01-01

    In this article, the author discusses how the creation of enrollment management organizations separate from traditional student affairs and academic affairs divisions have caused negative impacts on student learning. A relatively new organizational structure that first appeared in the mid-1970s, enrollment management has its roots in…

  1. Ulva additions alter soil biogeochemistry and negatively impact Spartina alterniflora growth

    Science.gov (United States)

    Decaying mats of Ulva can be washed into salt marshes by the tides as large wrack deposits, especially in eutrophic estuaries, where they can negatively impact marsh vegetation. We report on a series of field and laboratory mesocosm experiments where we examined the effects of d...

  2. Cross-sections for the formation of negative ions by electron impact on silane

    Science.gov (United States)

    Srivastava, S. K.; Krishnakumar, E.; De A. E Souza, A. C.

    1991-01-01

    Cross-sections and appearance potentials for the production of various negative ion species by electron impact on SiH4 have been measured. They are compared with two previous measurements which widely differ with each other. Hess' law has been applied to predict the various possible channels of dissociation.

  3. Mothers' perceptions of the negative impact on TV food ads on children's food choices.

    Science.gov (United States)

    Yu, Jay Hyunjae

    2012-10-01

    This exploratory study investigates the opinions of mothers who have at least one child between the ages of 7 and 12 in terms of the impact of TV food advertising on their children. This research also examines whether there is any third person effect active in mothers' opinions of TV food advertising aimed at children by asking them about both the impact on their own children, and the children of strangers. The results reveal that most mothers in the study have generally negative attitudes toward TV food advertising aimed at children, but they believe that the children of strangers are more negatively impacted by exposure to the ads than their own children. PMID:22641145

  4. Elevated Appraisals of the Negative Impact of Naturally Occurring Life Events: A Risk Factor for Depressive and Anxiety Disorders

    OpenAIRE

    Espejo, Emmanuel P.; Hammen, Constance; Brennan, Patricia A.

    2012-01-01

    The tendency to appraise naturally occurring life events (LEs) as having high negative impact may be a predisposing factor for the development of depression and anxiety disorders. In the current study, appraisals of the negative impact of recent LEs were examined in relationship to depressive and anxiety disorders in a sample of 653 adolescents who were administered diagnostic and life stress interviews at ages 15 and 20. Participants’ appraisals of the negative impact of LEs reported at age ...

  5. The impact of negative forensic evidence on mock jurors' perceptions of a trial of drug-facilitated sexual assault.

    Science.gov (United States)

    Jenkins, Gwen; Schuller, Regina A

    2007-08-01

    Legal concerns with regard to the adverse impact of a negative toxicological screening for date-rape drugs in a case of drug-facilitated sexual assault (DFSA) were the focus of a recent Canadian case (R. v. Alouache, 2003). To assess the impact of a negative forensic report, as well as the impact of expert testimony explaining the many factors that may contribute to a negative outcome, participants (N=171) received a written trial stimulus in which the forensic evidence (negative report, negative report plus expert testimony, no negative report and no expert testimony control) and the complainant's beverage consumption (alcohol, cola) were systematically varied. Results indicate that a negative finding in the absence of expert testimony produced greater verdict leniency and more favourable evaluations of the defendant's case. In contrast, no differences were found between the case in which the expert testified and a case in which the negative report and expert testimony were omitted. PMID:17211690

  6. Buffering Negative Impacts of Divorce on Children: Evaluating Impact of Divorce Education

    Science.gov (United States)

    Crawford, Jennifer K.; Riffe, Jane; Trevisan, Dominic A.; Adesope, Olusola O.

    2014-01-01

    Following the call for more stringent evaluation methodology and recently documented national Extension presence in the field of divorce education for parents and children, the study reported here describes a local multi-level evaluation to capture program impact of a stakeholder-accepted divorce education program. Using a post-then-pre…

  7. Prognostic Impact of the Signet Ring Cell Type in Node-Negative Gastric Cancer

    OpenAIRE

    Pengfei Kong; Ruiyan Wu; Chenlu Yang; Qirong Geng; Jianjun Liu; Shangxiang Chen; Xuechao Liu; Minting Ye; Wenzhuo He; Qiong Yang; Liangping Xia; Dazhi Xu

    2016-01-01

    Little is known regarding the prognostic impact of the signet ring cell (SRC) histotype on negative lymph nodes (LNs) in gastric cancer (GC). In this study, we aimed to investigate the differences between SRC and non-SRC GC patients without LN metastasis. The medical records of patients with GC who underwent gastrectomy at Sun Yat-Sen University Cancer Centre from 1996 to 2012 were reviewed to analyse the clinicopathologic characteristics associated with survival. A total of 480 cases of GC p...

  8. Elevated Appraisals of the Negative Impact of Naturally Occurring Life Events: A Risk Factor for Depressive and Anxiety Disorders

    Science.gov (United States)

    Espejo, Emmanuel Peter; Hammen, Constance; Brennan, Patricia A.

    2012-01-01

    The tendency to appraise naturally occurring life events (LEs) as having high negative impact may be a predisposing factor for the development of depression and anxiety disorders. In the current study, appraisals of the negative impact of recent LEs were examined in relationship to depressive and anxiety disorders in a sample of 653 adolescents…

  9. The Role of the Teacher in Helping Learners Overcome the Negative Impact of Child Sexual Abuse: A South African Perspective

    Science.gov (United States)

    Phasha, Tlakale Nareadi

    2008-01-01

    Current literature suggesting the negative impact of childhood experiences of sexual abuse on school functioning makes it imperative to consider the role of the teacher in helping survivors overcome the negative impact of such experiences. Schools cannot ignore the reason why some learners cannot learn. This article presents the findings of a…

  10. Negative and positive impact of internet addiction on young adults: Empericial study in Malaysia

    Directory of Open Access Journals (Sweden)

    Syed Shah Alam

    2014-05-01

    Full Text Available Purpose: The purpose of this study is to explore and identify the impact of internet addictions of young adults in Malaysia. There are six impacts identified, of which five are negative impacts and one is positive impact.Design/methodology/approach: This study comprised sample of 200 young adults in Malaysia. A cross-sectional research design was used to examine the impact of Internet addiction. Data were gathered based on personal administered questionnaire.Findings and Originality/value: This study results show that five negative impacts of excessive internet usages such as interpersonal problem, behavioural problem, physical problem, psychological problem, and work problem of young adults.The young adults believed that the internet usage can help them to improve their skills for doing their work better. This study also reveals that males have a great impact on working problems, psychological problems, behavioural problems and interpersonal problems than female adults. On the other hand, females are leading with their physical problems by getting Internet addiction.Research limitations/implications: The data for this study are collected by self-administered questionnaire, a method with well-known shortcomings. Secondly, this study done only on young adults from only two universities in Malaysia.Practical implications: An important implication of this research is that the interesting findings give some insight to the Internet users to focus on improving Internet usage habits. Originality/value: The findings are original and unique and are based on the literature from different western researches. The results are based on a sample of young adults in Malaysia. The research findings are useful to academics and heavy Internet users those are hooked with Internet to their everyday life.

  11. Biocrust-forming mosses mitigate the negative impacts of increasing aridity on ecosystem multifunctionality in drylands.

    Science.gov (United States)

    Delgado-Baquerizo, Manuel; Maestre, Fernando T; Eldridge, David J; Bowker, Matthew A; Ochoa, Victoria; Gozalo, Beatriz; Berdugo, Miguel; Val, James; Singh, Brajesh K

    2016-03-01

    The increase in aridity predicted with climate change will have a negative impact on the multiple functions and services (multifunctionality) provided by dryland ecosystems worldwide. In these ecosystems, soil communities dominated by mosses, lichens and cyanobacteria (biocrusts) play a key role in supporting multifunctionality. However, whether biocrusts can buffer the negative impacts of aridity on important biogeochemical processes controlling carbon (C), nitrogen (N), and phosphorus (P) pools and fluxes remains largely unknown. Here, we conducted an empirical study, using samples from three continents (North America, Europe and Australia), to evaluate how the increase in aridity predicted by climate change will alter the capacity of biocrust-forming mosses to modulate multiple ecosystem processes related to C, N and P cycles. Compared with soil surfaces lacking biocrusts, biocrust-forming mosses enhanced multiple functions related to C, N and P cycling and storage in semiarid and arid, but not in humid and dry-subhumid, environments. Most importantly, we found that the relative positive effects of biocrust-forming mosses on multifunctionality compared with bare soil increased with increasing aridity. These results were mediated by plant cover and the positive effects exerted by biocrust-forming mosses on the abundance of soil bacteria and fungi. Our findings provide strong evidence that the maintenance of biocrusts is crucial to buffer negative effects of climate change on multifunctionality in global drylands. PMID:26452175

  12. Video-games do not negatively impact adolescent academic performance in science, mathematics or reading.

    Directory of Open Access Journals (Sweden)

    Aaron Drummond

    Full Text Available Video-gaming is a common pastime among adolescents, particularly adolescent males in industrialized nations. Despite widespread suggestions that video-gaming negatively affects academic achievement, the evidence is inconclusive. We reanalyzed data from over 192,000 students in 22 countries involved in the 2009 Programme for International Student Assessment (PISA to estimate the true effect size of frequency of videogame use on adolescent academic achievement in science, mathematics and reading. Contrary to claims that increased video-gaming can impair academic performance, differences in academic performance were negligible across the relative frequencies of videogame use. Videogame use had little impact on adolescent academic achievement.

  13. Video-games do not negatively impact adolescent academic performance in science, mathematics or reading.

    Science.gov (United States)

    Drummond, Aaron; Sauer, James D

    2014-01-01

    Video-gaming is a common pastime among adolescents, particularly adolescent males in industrialized nations. Despite widespread suggestions that video-gaming negatively affects academic achievement, the evidence is inconclusive. We reanalyzed data from over 192,000 students in 22 countries involved in the 2009 Programme for International Student Assessment (PISA) to estimate the true effect size of frequency of videogame use on adolescent academic achievement in science, mathematics and reading. Contrary to claims that increased video-gaming can impair academic performance, differences in academic performance were negligible across the relative frequencies of videogame use. Videogame use had little impact on adolescent academic achievement. PMID:24699536

  14. Organizational impact of workaholism: suggestions for researching the negative outcomes of excessive work.

    Science.gov (United States)

    Porter, G

    1996-01-01

    Excessive work can be viewed as an addictive behavior, and, as such, it will have a negative impact on the setting in which it occurs, as well as on the individual. This change in perspective is needed to address dysfunctional behavior patterns that interfere with organizational operations. Similarities with other addictions include identity issues, rigid thinking, withdrawal, progressive involvement, and denial. These factors influence decision making and goals of the workaholic. They also interfere with effectiveness by distorting interpersonal relations. Suggestions for further research build on established organizational topics that coincide with characteristics of an addictive pattern. PMID:9547036

  15. A critical realist perspective on decoupling negative environmental impacts from housing sector growth and economic growth

    DEFF Research Database (Denmark)

    Xue, Jin

    2012-01-01

    The question that motivates this article has been a matter of dispute: Is it possible to combine perpetual economic growth and longterm environmental sustainability based on the premise that economic growth can be fully decoupled from negative environmental impacts? The article addresses this...... be increased at a rate sufficient to compensate for continual growth in the volume of housing stock. A further elaboration of the topic at an ontological level leads to the conclusion that continual economic growth and long-term environmental sustainability can hardly be combined....... question from the position of critical realism. An empirical study focusing on the housing sector is conducted, indicating that housing stock growth and economic growth have been, at best, weakly decoupled from environmental impacts. In the long run, it seems implausible that the degree of decoupling can...

  16. Evidence for the negative impact of reward on self-regulated learning.

    Science.gov (United States)

    Wehe, Hillary S; Rhodes, Matthew G; Seger, Carol A

    2015-01-01

    The undermining effect refers to the detrimental impact rewards can have on intrinsic motivation to engage in a behaviour. The current study tested the hypothesis that participants' self-regulated learning behaviours are susceptible to the undermining effect. Participants were assigned to learn a set of Swahili-English word pairs. Half of the participants were offered a reward for performance, and half were not offered a reward. After the initial study phase, participants were permitted to continue studying the words during a free period. The results were consistent with an undermining effect: Participants who were not offered a reward spent more time studying the words during the free period. The results suggest that rewards may negatively impact self-regulated learning behaviours and provide support for the encouragement of intrinsic motivation. PMID:26106977

  17. Could shading reduce the negative impacts of drought on coffee? A morphophysiological analysis.

    Science.gov (United States)

    Cavatte, Paulo C; Oliveira, Alvaro A G; Morais, Leandro E; Martins, Samuel C V; Sanglard, Lílian M V P; DaMatta, Fábio M

    2012-02-01

    Based on indirect evidence, it was previously suggested that shading could attenuate the negative impacts of drought on coffee (Coffea arabica), a tropical crop species native to shady environments. A variety (47) of morphological and physiological traits were examined in plants grown in 30-l pots in either full sunlight or 85% shade for 8 months, after which a 4-month water shortage was implemented. Overall, the traits showed weak or negligible responses to the light × water interaction, explaining less than 10% of the total data variation. Only slight variations in biomass allocation were observed in the combined shade and drought treatment. Differences in relative growth rates were mainly associated with physiological and not with morphological adjustments. In high light, drought constrained the photosynthetic rate through stomatal limitations with no sign of apparent photoinhibition; in low light, such constraints were apparently linked to biochemical factors. Sun-grown plants displayed osmotic adjustments, decreased tissue elasticities and improved long-term water use efficiencies, especially under drought. Regardless of the water availability, higher concentrations of lipids, total phenols, total soluble sugars and lignin were found in high light compared to shade conditions, in contrast to the effects on cellulose and hemicellulose concentrations. Proline concentrations increased in water-deprived plants, particularly those grown under full sun. Phenotypic plasticity was much higher in response to the light than to the water supply. Overall, shading did not alleviate the negative impacts of drought on the coffee tree. PMID:21939445

  18. Decoupling in order to reduce the negative environmental impact from transport logistics. From theory to reality

    International Nuclear Information System (INIS)

    This report deals with the issue of decoupling from a bottom-up approach and thereby works as a complementary report to 'A closer Look at Road Freight Transport and Economic Growth in Sweden' published by the Swedish Environmental Protection Agency. The freight transport logistics market is steadily growing in Sweden and the EU. Between 1990 and 2002 the growth in Sweden was 15 % and in EU15 33 %. The increase has primarily occurred within road freight. Economics of scale and low cost for transport logistics services drives centralisation both within trade and manufacturing. This leads to an increase of the transport work. The objective of this report is to describe decoupling from a business perspective. We have therefore focused on industrial sectors that are the largest drivers of transportation demand. In addition we have included the most relevant providers of transport services. In brief this means - Buyers of transport logistics: Clothing, Furniture, Pulp and paper, Oil and energy, Steel, Mechanical industry, Fast moving goods, and Construction. As sellers of transport logistics services we have focused on: Road transport, Rail transport, Sea transport, and Forwarders. During the work we have ended up in a broad perspective when defining decoupling. In general we work with the concept of decoupling defined as 'breaking the connection between the environmentally negative impacts from transport logistics and economic growth'. The negative impacts we include are: Resource use, Climate, Nature, Health, and Accidents. Our focus is a European perspective from a Swedish platform and our time perspective is from relatively narrow to 2020. The business sector raises doubt on the idea of decoupling transport work and GNP. They are however more positive when discussing decoupling economic growth from negative environmental impacts. When analysing the underlying factors for this development we can se a tremendous growth in the global trade. the paper discuses how

  19. The Impact of Negative Stereotypes & Representations of African-Americans in the Media and African-American Incarceration

    OpenAIRE

    Johnson, Tamara Therese

    2012-01-01

    The purpose of this study was to investigate the sociological impact of public polices enacted during slavery in the United States. Another goal was to discover whether the negative stereotypes of African-Americans in film are related to the reinforcement of negative perceptions established during slavery. Finally, a review of the disparate outcomes produced by new discriminatory policies within the criminal justice system details the impact of current policies that disproportionately impac...

  20. Assessing the Personal Negative Impacts of Hooking Up Experienced by College Students: Gender Differences and Mental Health.

    Science.gov (United States)

    Napper, Lucy E; Montes, Kevin S; Kenney, Shannon R; LaBrie, Joseph W

    2016-09-01

    Hooking up is a normative behavior among college students that is associated with a range of positive and negative consequences. While previous research has primarily focused on women's negative experiences of hooking up, the current study explored the relationships among hooking up behaviors, psychological distress, and a broad range of negative effects of hooking up in both male and female college students. Using a multisite sample of college students, we developed the 14-item Negative Impact of Hookups Inventory (NIHI) to assess negative health outcomes, emotional responses, and social consequences associated with hooking up. Unprotected sex and having more hookup partners were associated with greater negative experiences of hooking up. Contrary to expectations, there were no gender differences in the total number of negative hookup effects, although men reported more frequent hookups. In addition, negative impacts of hooking up were positively associated with psychological distress regardless of gender. The NIHI may offer a useful tool to assess the negative impacts of hooking up. Understanding students' hookup experiences is an important step toward developing targeted health interventions related to hooking up behavior in young adult populations. PMID:26445346

  1. Understanding of a negative bowel screening result and potential impact on future symptom appraisal and help-seeking behaviour

    DEFF Research Database (Denmark)

    Barnett, Karen N; Weller, David; Smith, Steve;

    2016-01-01

    ) emotional response to a negative FOBt, (ii) understanding the limitations of FOBt screening, (iii) symptom knowledge and interpretation and (iv) over-reassurance from a negative FOBt. Participants were reassured by a negative FOBt, but there was variability in the extent to which the result was interpreted......BACKGROUND: Colorectal cancer (CRC) screening using a faecal occult blood test (FOBt) has the potential to reduce cancer-related mortality. Symptom vigilance remains crucial as a proportion of cancers will be diagnosed between screening rounds. A negative FOBt has the potential to influence how...... participants respond to future symptoms of CRC. OBJECTIVE: To explore (i) understanding of a negative FOBt and (ii) the potential impact of a negative FOBt upon future symptom appraisal and help-seeking behaviour. DESIGN: Qualitative methodology utilizing focus groups with participants who received a negative...

  2. No time to lose: Negative impact on law student wellbeing may begin in year one

    Directory of Open Access Journals (Sweden)

    Molly Townes O'Brien

    2011-07-01

    Full Text Available Preliminary results of a pilot study of law students suggest that, during the first year of law study, students may experience changes in thinking styles, stress levels, and satisfaction with life. Although further inquiry into the cause of law student distress is necessary, the authors consider certain assumptions underlying the legal curriculum—particularly the conception of a lawyer as adversarial, emotionally detached, and competitive—to be possible sources of the negative impact on student wellbeing.  It is suggested that legal educators should re-examine their curricula, particularly their conception of what it means to be a lawyer, and think creatively about ways that law schools may encourage healthier approaches to the study of law.

  3. The impact of screening-test negative samples not enumerated by MPN

    DEFF Research Database (Denmark)

    Corbellini, Luis Gustavo; Ribeiro Duarte, Ana Sofia; de Knegt, Leonardo; Silva, Luis Eduardo da; Cardoso, Marisa; Nauta, Maarten

    2015-01-01

    In microbiological surveys, false negative results in detection tests precluding the enumeration by MPN may occur. The objective of this study was to illustrate the impact of screening test failure on the probability distribution of Salmonella concentrations in pork using a Bayesian method. A total...... of 276 swab samples in four slaughter steps (69 samples in each slaughter step: after dehairing, after singeing, after evisceration, and before chilling) were screened for Salmonella and enumerated by the MPN method. Salmonella contamination data were fitted to a lognormal distribution by using a...... Bayesian model that uses the number of positive tubes at each dilution in an MPN analysis to estimate the parameters of the concentration distribution. With Salmonella paired data, three data sets were used for each slaughter step: one that includes the positives in the screening test only, a second one...

  4. The negative impacts of the global economic downturn on funding decentralised energy in the UK

    International Nuclear Information System (INIS)

    Over the years, a number of governmental policies have been developed in the UK that offer grants for the installation of distributed energy technologies or financial rewards per unit of electricity/heat generated from renewable and sustainable sources. The current economic climate however has meant that budget cuts have affected almost all government departments; consequently such policies have been adversely impacted. The alterations/modifications to many schemes have resulted in either a reduction in the funding available through these, changes to the eligibility of certain technologies or scales of generation or policy cancellations. The programmes affected include the Feed-In Tariff Scheme, Renewable Heat Incentive and Low Carbon Buildings Programme, among others. The adjustments for these are detailed herein, followed by the impacts these have had on the deployment rates of decentralised energy, especially microgeneration. Since costs are often one of the most significant factors constraining deployment of these technologies, reductions in funding opportunities have made these less financially-viable. Whilst there are still applications for funding under the available schemes, there has been considerably reduced levels of requests for financial support, thus future deployment rates will most likely be negatively affected. The prospects of these technologies in this context are then considered. - Highlights: ► Costs are often a significant barrier limiting distributed energy deployment. ► The economic downturn has reduced funding for policies aiding distributed energy. ► Installing decentralised energy technologies is now less financially-viable. ► This is now starting to negatively affect uptake rates of microgeneration.

  5. Complementary and Alternative Medicine Usage in Skin Diseases and the Positive and Negative Impacts on Patients

    Directory of Open Access Journals (Sweden)

    Gülşen Tükenmez Demirci

    2012-12-01

    Full Text Available Objective: Our purpose was to compare the sosciodemographical differences between Complementary and Alternative medicine (CAM users and non users with skin diseases and to investigate the positive and negative impacts of CAM among patients. Methods: The patients with dermatological conditions attending the dermatology outpatient clinic were enrolled to the study randomly. The sociodemographical properties, diagnosis of the skin diseases, duration of the disease, CAM usage and duration of usage and the positive and negative impacts of the treatments were recorded. Results: A total of 522 (302 female, 220 male, median age 34.8±16.7 patients were enrolled in the study. Eighty-eight patients (16.8% were found to have used a CAM method. The mean age of CAM users (28.2±14.3 were statistically lower than non users (36.0±16.9 (p=0.000 <0.05. The disease duration of CAM users (4.3±5.5 year was statistically longer than non-users (2.8±5.2 year. The CAM methods were mostly preferred in acne vulgaris disease (31.8%, and the mostly used CAM method was herbal therapies (59.1%. We found that 16 (18.2% out of 88 CAM users had side effects from CAM treatment while nine patients (10.3% improved. Conclusion: Complementary and alternative medicine usage is not frequent among skin diseases. The patients with longer disease duration are more prone to use CAM. The side effects rarely occur due to CAM use and we ascertain that very rarely do patients benefit from CAM methods.

  6. Increasing risk for negative ozone impacts on vegetation in northern Sweden

    International Nuclear Information System (INIS)

    Trends were found for increasing surface ozone concentrations during April-September in northern Sweden over the period 1990-2006 as well as for an earlier onset of vegetation growing season. The highest ozone concentrations in northern Sweden occurred in April and the ozone concentrations in April showed a strong increasing trend. A model simulation of ozone flux for Norway spruce indicated that the provisional ozone flux based critical level for forests in Europe is exceeded in northern Sweden. Future climate change would have counteracting effects on the stomatal conductance and needle ozone uptake, mediated on the one hand by direct effect of increasing air temperatures and on the other through increasing water vapour pressure difference between the needles and air. Thus, there is a substantial and increasing risk for negative impacts of ozone on vegetation in northern Sweden, related mainly to increasing ozone concentrations and an earlier onset of the growing season. - Increasing risks for ozone impacts on vegetation in northern Sweden

  7. Negative impact of pretreatment anemia on local control after neoadjuvant chemoradiotherapy and surgery for rectal cancer

    International Nuclear Information System (INIS)

    Although anemia is considered to be a contributor to intra-tumoral hypoxia and tumor resistance to ionizing radiation in cancer patients, the impact of pretreatment anemia on local control after neoadjuvant concurrent chemoradiotherapy (NACRT) and surgery for rectal cancer remains unclear. We reviewed the records of 247 patients with locally advanced rectal cancer who were treated with NACRT followed by curative-intent surgery. The patients with anemia before NACRT (36.0%, 89/247) achieved less pathologic complete response (pCR) than those without anemia (p = 0.012). The patients with pretreatment anemia had worse 3-year local control than those without pretreatment anemia (86.0% vs. 95.7%, p = 0.005). Multivariate analysis showed that pretreatment anemia (p = 0.035), pathologic tumor and nodal stage (p = 0.020 and 0.032, respectively) were independently significant factors for local control. Pretreatment anemia had negative impacts on pCR and local control among patients who underwent NACRT and surgery for rectal cancer. Strategies maintaining hemoglobin level within normal range could potentially be used to improve local control in rectal cancer patients.

  8. Negative impact of pretreatment anemia on local control after neoadjuvant chemoradiotherapy and surgery for rectal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hye Bin; Park, Hee Chul; Park, Won [Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); and others

    2012-09-15

    Although anemia is considered to be a contributor to intra-tumoral hypoxia and tumor resistance to ionizing radiation in cancer patients, the impact of pretreatment anemia on local control after neoadjuvant concurrent chemoradiotherapy (NACRT) and surgery for rectal cancer remains unclear. We reviewed the records of 247 patients with locally advanced rectal cancer who were treated with NACRT followed by curative-intent surgery. The patients with anemia before NACRT (36.0%, 89/247) achieved less pathologic complete response (pCR) than those without anemia (p = 0.012). The patients with pretreatment anemia had worse 3-year local control than those without pretreatment anemia (86.0% vs. 95.7%, p = 0.005). Multivariate analysis showed that pretreatment anemia (p = 0.035), pathologic tumor and nodal stage (p = 0.020 and 0.032, respectively) were independently significant factors for local control. Pretreatment anemia had negative impacts on pCR and local control among patients who underwent NACRT and surgery for rectal cancer. Strategies maintaining hemoglobin level within normal range could potentially be used to improve local control in rectal cancer patients.

  9. Activation of PPAR by Rosiglitazone Does Not Negatively Impact Male Sex Steroid Hormones in Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Mahmoud Mansour

    2009-01-01

    Full Text Available Peroxisome proliferator-activated receptor gamma (PPAR activation decreased serum testosterone (T in women with hyperthecosis and/or polycystic ovary syndrome and reduced the conversion of androgens to estradiol (E2 in female rats. This implies modulation of female sex steroid hormones by PPAR. It is not clear if PPAR modulates sex steroid hormones in diabetic males. Because PPAR activation by thiazolidinedione increased insulin sensitivity in type 2 diabetes, understanding the long term impact of PPAR activation on steroid sex hormones in males is critical. Our objective was to determine the effect of PPAR activation on serum and intratesticular T, luteinizing hormone (LH, follicle stimulating hormone (FSH and E2 concentrations in male Zucker diabetic fatty (ZDF rats treated with the PPAR agonist rosiglitazone (a thiazolidinedione. Treatment for eight weeks increased PPAR mRNA and protein in the testis and elevated serum adiponectin, an adipokine marker for PPAR activation. PPAR activation did not alter serum or intratesticular T concentrations. In contrast, serum T level but not intratesticular T was reduced by diabetes. Neither diabetes nor PPAR activation altered serum E2 or gonadotropins FSH and LH concentrations. The results suggest that activation of PPAR by rosiglitazone has no negative impact on sex hormones in male ZDF rats.

  10. The Effects of Positive versus Negative Impact Reflection on Change in Job Performance and Work-Life Conflict

    Directory of Open Access Journals (Sweden)

    M. Teresa eCardador

    2014-11-01

    Full Text Available Research on task significance and relational job design suggests that information from beneficiaries of one’s work fosters perceptions of impact, and thus improved work outcomes. This paper presents results from a longitudinal field experiment examining the effect of another strategy for fostering perceptions of impact – engaging employees in regular reflection about how their work benefits others. With a sample of professionals from multiple organizations, this longitudinal study examined the effect on job performance and work-life conflict of both positive and negative impact reflection. Results show that negative impact reflection had a pronounced negative effect on job performance, but no effect on work-life conflict. Positive impact reflection had a weak positive effect on work-life conflict, but no significant effect on job performance. The direction of effects seen in the no intervention condition mirrored that of the negative impact reflection condition, suggesting a possible buffering effect for positive impact reflection. This research provides empirical and theoretical contributions to the literatures on relational job design and task significance.

  11. Impact of maternal negative affectivity on light alcohol use and binge drinking during pregnancy

    DEFF Research Database (Denmark)

    Stene-Larsen, Kim; Torgersen, Leila; Strandberg-Larsen, Katrine;

    2013-01-01

    To investigate whether maternal negative affectivity, a tendency to frequent negative emotions and views, is associated with light alcohol use and binge drinking during pregnancy.......To investigate whether maternal negative affectivity, a tendency to frequent negative emotions and views, is associated with light alcohol use and binge drinking during pregnancy....

  12. Impact of Negative Quality Inconsistency on Brand Loyalty – Case of Croatian Food Market

    Directory of Open Access Journals (Sweden)

    Martina Ferenčić

    2015-03-01

    Full Text Available Attracting and keeping consumers’ loyalty in Fast Moving Consumer Goods segment became the main concern for all producing companies and retailers, too. Many marketing researchers argue that product or service quality perception is one of the key elements in brand loyalty building process. When talking about food market, one has to be aware that food consumption has direct impact on human health and, in that context, process of building brand loyalty for food brands is not possible, or it can be hard, if the product quality of food brands is not on the expected level and according to defined food quality standards. The goal of this paper was to understand aspects of connection between food product quality and brand loyalty process better and to explore how problems with negative quality inconsistency in different food categories can influence brand loyalty. An empirical research (on-line survey was conducted to prove and explain the connection between food product quality and food brand loyalty. The research results shows that the main reasons for being loyal to a certain food brand or product are related mostly to positive brand experience, high and stabile product quality, and recognizable taste. In the context of these research results, it can be concluded that long term consumer satisfaction as a factor in food brand loyalty process depends on stabile product quality, so food manufacturers or food brand owners should be focused on preventing or minimizing the aspect of negative quality issues. Regarding research limitations, the study was conducted only on users from Croatian market; so broadening the survey to other markets should give a clearer view on the connection between food product quality and brand loyalty process.

  13. The Impact of Parental Modeling and Permissibility on Alcohol Use and Experienced Negative Drinking Consequences in College

    OpenAIRE

    Abar, Caitlin; Abar, Beau; Turrisi, Rob

    2009-01-01

    This study examined the impact of parental modeled behavior and permissibility of alcohol use in late high school on the alcohol use and experienced negative drinking consequences of college students. Two-hundred ninety college freshmen at a large university were assessed for perceptions of their parents’ permissibility of alcohol use, parents’ alcohol-related behavior, and own experienced negative consequences associated with alcohol use. Results indicate that parental permissibility of alco...

  14. Recreational Physical Activity Ameliorates Some of the Negative Impact of Major Depression on Health-Related Quality of Life

    OpenAIRE

    ScottBurtonPatten

    2013-01-01

    Background: Major depressive episodes (MDEs) have a negative effect on health-related quality of life (HRQoL). The objective of this study was to determine whether recreational physical activity can ameliorate some of this negative impact. Methods: The data source for the study was the Canadian National Population Health Survey (NPHS). The NPHS is a longitudinal study that has collected data from a representative cohort of 15,254 community residents. Sixteen years of follow-up data are ...

  15. The impact of surgical site occurrences and the role of closed incision negative pressure therapy.

    Science.gov (United States)

    Willy, Christian; Engelhardt, Michael; Stichling, Marcus; Grauhan, Onnen

    2016-09-01

    Surgical site occurrences are observed in up to 60% of inpatient surgical procedures in industrialised countries. The most relevant postoperative complication is surgical site infection (SSI) because of its impact on patient outcomes and enormous treatment costs. Literature reviews ('SSI', 'deep sternal wound infections' (DSWI), 'closed incision negative pressure wound therapy' (ciNPT) were performed by electronically searching MEDLINE (PubMed) and subsequently using a 'snowball' method of continued searches of the references in the identified publications. Search criteria included publications in all languages, various study types and publication in a peer-reviewed journal. The SSI literature search identified 1325, the DSWI search 590 and the ciNPT search 103 publications that fulfilled the search criteria. Patient-related SSI risk factors (diabetes mellitus, obesity, smoking, hypertension, female gender) and operation-related SSI risk factors (re-exploration, emergency operations, prolonged ventilation, prolonged operation duration) exist. We found that patient- and operation-related SSI risk factors were often different for each speciality and/or operative procedure. Based on the evidence, we found that high-risk incisions (sternotomy and incisions in extremities after high-energy open trauma) are principally recommended for ciNPT use. In 'lower'-risk incisions, the addition of patient-related or operation-related risk factors justifies the application of ciNPT. PMID:27547962

  16. Negative impact of trading in human organs on the development of transplantation in the Middle East.

    Science.gov (United States)

    Abouna, G M

    1993-06-01

    With recent advances in transplanting human organs, increasing numbers of people in need of replacement organs are opting for transplantation. These medical advances and the subsequent public demand have, however, led to a supply-demand problem in which more patients request replacement organs than the number which are readily available. A flourishing international trade in human organs has developed in response to the comparatively high demand for organs. Organs in demand are bought from the poor for transplantation to wealthy clientele. For their contacts and services, brokers, private hospitals, and physicians earn enormous profits. It is estimated that more than 2000 kidneys since 1990 have been sold annually in India to wealthy recipients from the Middle East, the Far East, and Europe. The phenomenon has alarmed the medical profession, the public, and many governments and has been condemned by all major religions and most transplant societies. The author also condemns the sale of human organs as being damaging to the cause of transplantation as well as many other moral, religious, and ethical values and beliefs of society. The sale of organs negatively affects their altruistic donation by the public as well as the development of local cadaver procurement programs by national governments. All forms of paid organ donation should therefore be made illegal in all countries of the world. Sections consider the donor, the recipient, local transplant programs, the medical profession, and the impact upon society. PMID:8516911

  17. Climate warming mediates negative impacts of rapid pond drying for three amphibian species.

    Science.gov (United States)

    O'Regan, Sacha M; Palen, Wendy J; Anderson, Sean C

    2014-04-01

    Anthropogenic climate change will present both opportunities and challenges for pool-breeding amphibians. Increased water temperature and accelerated drying may directly affect larval growth, development, and survival, yet the combined effects of these processes on larvae with future climate change remain poorly understood. Increased surface temperatures are projected to warm water and decrease water inputs, leading to earlier and faster wetland drying. So it is often assumed that larvae will experience negative synergistic impacts with combined warming and drying. However, an alternative hypothesis is that warming-induced increases in metabolic rate and aquatic resource availability might compensate for faster drying rates, generating antagonistic larval responses. We conducted a mesocosm experiment to test the individual and interactive effects of pool permanency (permanent vs. temporary) and water temperature (ambient vs. (+) -3 degrees C) on three anurans with fast-to-slow larval development rates (Great Basin spadefoot [Spea intermontana], Pacific chorus frog [Pseudacris regilla], and northern red-legged frog [Rana aurora]). We found that although tadpoles in warmed pools reached metamorphosis 15-17 days earlier, they did so with little cost (amphibians. However, they also demonstrate that antagonistic responses are difficult to predict, which poses a challenge to proactive conservation and management. Our study highlights the importance of considering the nature of multiple stressor interactions as amphibians are exposed to an increasing number of anthropogenic threats. PMID:24933805

  18. Positive and Negative Impacts of Cross-border M&A

    Institute of Scientific and Technical Information of China (English)

    裴长洪; 林江

    2007-01-01

    Mergers and acquisitions of Chinese enterprises by foreign investors have moved onto the public radar in recent years.To date,the M&A frenzy has drawn widespread attention,with a mixed reaction from proponents and opponents.Proponents consider such mergers and acquisitions conducive to realizing strategic readjustment of the national economic structure,optimizing resource allocation and improving the corporate governance structure.Opponents,however,are concerned that foreign mergers and acquisitions may jeopardize China’s industrial security and erode the executive power of the central government in undertaking industrial development planning.Are the benefits of M&A outweighed by the costs,or vice versa? The focus column of this edition features two articles which debate this issue from opposing viewpoints.In the article"Positive and Negative Impacts of Cross-border M&A",the authors consider foreign M(?)A to be a new way of boosting the level of foreign investment utilization,and advocate China taking full advantage of this approach.The authors of the article"Self-Improvement Or Self-Mutilation",meanwhile,hold foreign M&A to blame for state-owned asset erosion,and insist that China should oppose mergers and acquisitions of key state- owned enterprises by foreign investors at fire-sale prices.

  19. Asymmetric impact of the physiological effect of carbon dioxide on hydrological responses to instantaneous negative and positive CO2 forcing

    Science.gov (United States)

    Abe, Manabu; Shiogama, Hideo; Yokohata, Tokuta; Emori, Seita; Nozawa, Toru

    2015-10-01

    We conducted sensitivity experiments using a coupled atmosphere-ocean general circulation model to examine the asymmetry between the hydrological responses to instantaneous positive and negative CO2 forcing and the impact of the CO2 physiological effects (CDPEs) on these responses. This study focuses on the fast response occurring on time scales shorter than 1 year after imposing CO2 forcing. Experiments investigating the CO2 physiological effect show that the fast response of precipitation to positive CO2 forcing is a decrease in the global and annual mean, whereas that of negative forcing is an increase the global and annual mean precipitation. The fast global precipitation response to negative forcing is stronger than the response to positive forcing. In contrast, the experiments without the CDPE reveal similar magnitudes of the fast global precipitation responses to negative and positive CO2 forcing. Significant differences in the magnitudes of the fast precipitation response due to the CDPE are found in tropical regions such as the Amazon Basin, the Maritime Continents, and tropical Africa, where C3-type plants are common. The stomatal conductance of plant leaves is decreased by both positive and negative CO2 forcing, which suppress the transpiration from the leaves. Consequently, the CDPE enhances the asymmetry of the fast precipitation responses to positive and negative CO2 forcing. The asymmetric impact of CDPE requires a careful evaluation of future hydrological changes which is constrained by paleoclimate evidence.

  20. Client Violence and Its Negative Impacts on Work Attitudes of Child Protection Workers Compared to Community Service Workers

    Science.gov (United States)

    Shin, Junseob

    2011-01-01

    This study investigated the prevalence of client violence toward child protection workers and its negative impacts on the work attitudes of those workers compared with community service workers in South Korea. This study is based on the assumption that child protection workers are more vulnerable to violence than are community service workers…

  1. Adolescent Depression: Assessing the Impact of Negative Cognitions and Socioenvironmental Problems.

    Science.gov (United States)

    Simons, Ronald L.; Miller, Martin G.

    1987-01-01

    Examined the relative importance of socioenvironmental problems versus negative beliefs in explaining adolescent depression using a sample of high school students (N=423). Only one negative condition--low evaluation of self--was related to depression. Low parental support and employment problems were found to be predictors of depression and a…

  2. ERP Study of Affirmative and Negative Sentences' Impact on Self-Positivity Bias.

    Science.gov (United States)

    Li, Wenhui; Jiang, Zhongqing; Liu, Ying; Dan, Fei

    2016-08-01

    To explore how the sentence contexts affect self-positivity bias, we presented the participants with negation and affirmation sentences. Each sentence was ended with an adjective word describing human being's personality. The participants were asked to judge whether the sentences correctly described their own personalities. In affirmation sentences, the behavioral data showed that self-positivity bias occurred when participants considered the sentences to be in accordance with their personality; the ERP data showed that P200 amplitude was consistent with this behavioral result. In negation sentences, behavioral data showed self-positivity bias, regardless of whether the sentences were in accordance with participants' personality or not. However, the self-positivity bias was not observed in the ERP results from negation sentence. In summary, sentence type modulated the effect of self-positivity bias. The reason could be that processing affirmation and negation sentences requires different amount of cognitive resources. PMID:25980970

  3. Quantifying the Long-Term Impact of Negative Word of Mouth on Cash Flows and Stock Prices

    OpenAIRE

    Xueming Luo

    2009-01-01

    This paper seeks to quantify the long-term financial impact of negative word of mouth (NWOM), an issue that has long challenged extant research. We do so with real-world data on firm security prices. The developed time-series models innovatively uncover (1) short- and long-term effects of NWOM on cash flows, stock returns, and stock volatilities, and (2) NWOM's “wear-in” effects (i.e., it takes a number of months before the stock price impact of NWOM reaches the peak point) and “wear-out” eff...

  4. Do Digital Systems and Concept in Modern Public Service Production Have a Negative Impact on Citizens as End-Users?

    DEFF Research Database (Denmark)

    Pedersen, John Storm; Rendtorff, Jacob Dahl

    2016-01-01

    Do digital systems and concepts in modern public service production have a negative impact on citizens as end-users? To answer this research question, we shall first present our theoretical framework ‘the institutional logics perspective’ and show how we deploy this on modern public service...... production. Second, we claim that digital systems and concepts develop a new institutional logic within modern public service production: the ‘digital logic’. Third, we analyze and discuss the new logic´s possible impact on citizens as end-users. Fourth, we discuss the ethical dimensions of values and ethics...... in relation to public service production and digitizing....

  5. POSITIVE ATTITUDES AND NEGATIVE OF THE STUDENTS IN THE LEARNING OF MATHEMATICS, ITS IMPACT ON THE REPROACH AND TERMINAL EFFICIENCY

    OpenAIRE

    Ladislao Romero–Bojórquez; Alejandra Utrilla–Quiroz; Victor Manuel Utrilla–Quiroz

    2014-01-01

    The present investigation aimed to problematize "the positive and negative attitudes of students in learning mathematics, their impact on disapproval index and terminal efficiency." It was held in the Academic Unit "Rubén Jaramillo" of the Autonomous University of Sinaloa. Participants are students in the group 2 -01 to 2 -08 of the third semester of the morning session of the academic year 2009-2010. We analyze and interpret the attitudes that students have towards learning mathematics. From...

  6. Collective Oriented Culture and Its Negative Impact upon Oral English Teaching

    Institute of Scientific and Technical Information of China (English)

    肖春艳; 约翰·史密斯

    2015-01-01

    As one of the most distinguished features of Chinese Culture, collective oriented cul-ture is the deep structure of Chinese cultural psychology which has shaped Chinese character and inlfuenced their behavior. As a result of it, Chinese students suffer this negative effect from collective orientated culture when acquiring English, especially in oral English acquisition. TEFL teachers should be aware of cultural psychology and try their best to minimize its negative effect instead of neglecting or even en-larging it during oral English teaching.

  7. Impact of Metacognitive Acceptance on Body Dissatisfaction and Negative Affect: Engagement and Efficacy

    Science.gov (United States)

    Atkinson, Melissa J.; Wade, Tracey D.

    2012-01-01

    Objective: To investigate engagement in metacognitive acceptance and subsequent efficacy with respect to decreasing 2 risk factors for disordered eating, body dissatisfaction (BD), and negative affect (NA). Method: In a pilot experiment, 20 female undergraduates (M[subscript age] = 24.35, SD = 9.79) underwent a BD induction procedure, received…

  8. Mass media negative impact on the development and education of preschool children

    OpenAIRE

    Zarema Shhahytova; Anastasia Sitkova

    2014-01-01

    Globalization and modernization have both positive and negative sides. With the development of information technologies, new problems appear such as mass media influence on person, perception and education of preschool age children. The authors discuss the problem of mass media influence on preschool children education.

  9. Impact of physical maltreatment on the regulation of negative affect and aggression.

    Science.gov (United States)

    Shackman, Jessica E; Pollak, Seth D

    2014-11-01

    Physically maltreated children are at risk for developing externalizing behavioral problems characterized by reactive aggression. The current experiment tested the relationships between individual differences in a neural index of social information processing, histories of child maltreatment, child negative affect, and aggressive behavior. Fifty boys (17 maltreated) performed an emotion recognition task while the P3b component of the event-related potential was recorded to index attention allocation to angry faces. Children then participated in a peer-directed aggression task. Negative affect was measured by recording facial electromyography, and aggression was indexed by the feedback that children provided to a putative peer. Physically maltreated children exhibited greater negative affect and more aggressive behavior, compared to nonmaltreated children, and this relationship was mediated by children's allocation of attention to angry faces. These data suggest that physical maltreatment leads to inappropriate regulation of both negative affect and aggression, which likely place maltreated children at increased risk for the development and maintenance of externalizing behavior disorders. PMID:24914736

  10. Impact of Antimicrobial Stewardship Programme on Carbapenem Resistance in Gram Negative Isolates in an Indian Tertiary Care Hospital

    Directory of Open Access Journals (Sweden)

    Namita Jaggi

    2012-01-01

    Full Text Available Problem statement: Increasing Antimicrobial resistance in the World is constantly becoming a Global threat and there is an urgent need to prevent its spread. Various studies of last decade have shown reduced trends of antimicrobial resistance in the pathogens as an outcome of the Antimicrobial Stewardship Programs. In view of this, the present four years’ study was carried out to analyse the impact of Antimicrobial Stewardship Programs on carbapenem resistance in Gram negative isolates in a Tertiary care hospital in India. It involved a retrospective analysis of carbapenem resistance in Gram negatives for one year (July 2007 to June 2008, followed by prospective evaluation of the impact of stewardship interventions on resistance patterns (July 2008 to Jun 2011. Approach: Our study was staged into four parts: (1 July 2007 to June 2008: Resistance patterns of Gram negative isolates-E.coli, Klebsiella, Pseudomonas and Acinetobacter baumannii towards carbapenems were studied. (2 July 2008: Phase I intervention programme Implementation of an antibiotic policy in the hospital. (3 July 2008 to June 2010: The Impact of Phase I intervention programme was assessed subsequently. (4 July 2010 to June 2011: Phase II intervention programme: Formation and effective functioning of the antimicrobial stewardship committee. Results: The percentage resistance towards carbapenems in E.coli, Klebsiella, Pseudomonas and A. baumannii from July 2007-June 2008 was 1.07, 13.1, 21.3 and 12.5% respectively. Phase I intervention programme was initiated in July 2008 and Phase II in July 2010 and a subsequent reduction of 4.03% was observed in the carbapenem resistant Pseudomonas in the last stage of study period following the interventions. However the resistance in the other Gram negatives (E. coli, Klebsiella and A. baumannii rose and then stabilized. Conclusion: An antimicrobial stewardship programme with sustained and multifaceted efforts is essential to control the

  11. The impact of taxing working memory on negative and positive memories

    Directory of Open Access Journals (Sweden)

    Iris M. Engelhard

    2010-12-01

    Full Text Available Background: Earlier studies have shown that horizontal eye movement (EM during retrieval of a negative memory reduces its vividness and emotionality. This may be due to both tasks competing for working memory (WM resources. This study examined whether playing the computer game “Tetris” also blurs memory. Method: Participants recalled negative and positive memories in three conditions: recall only, recall with concurrent EM, and recall with playing Tetris. Before and after these conditions, vividness, emotionality, and physiological startle responses during recall were measured. Results: A reaction time task showed that EM and Tetris both draw on WM, compared to no dual-task. Compared to recall only, EM and Tetris decreased reported emotionality and startle responses. Conclusions: The effects of EM and Tetris did not differ, even though the tasks differed in the degree of taxing WM. This suggests that taxing WM and its effects on emotional memories may not be linearly related. Potential clinical implications are discussed.

  12. Attachment style impacts behavior and early oculomotor response to positive, but not negative, pictures

    OpenAIRE

    Silva, Catarina; Chaminade, Thierry; David, Da Fonseca; Santos, Andreia; Esteves, Francisco; Soares, Isabel; Deruelle, Christine

    2015-01-01

    The present study investigated whether oculomotor behavior is influenced by attachment styles. The Relationship Scales Questionnaire was used to assess attachment styles of forty-eight voluntary university students and to classify them into attachment groups (secure, preoccupied, fearful, and dismissing). Eye-tracking was recorded while participants engaged in a 3-seconds free visual exploration of stimuli presenting either a positive or a negative picture together with a neutral picture, all...

  13. Impact of physical maltreatment on the regulation of negative affect and aggression

    OpenAIRE

    Shackman, Jessica E.; Pollak, Seth D.

    2014-01-01

    Physically maltreated children are at risk for developing externalizing behavioral problems characterized by reactive aggression. The current experiment tested the relationships between individual differences in a neural index of social information processing, histories of child maltreatment, child negative affect, and aggressive behavior. Fifty boys (17 maltreated) performed an emotion recognition task while the P3b component of the event-related potential was recorded to index attention all...

  14. Video-Games Do Not Negatively Impact Adolescent Academic Performance in Science, Mathematics or Reading

    OpenAIRE

    Aaron Drummond; James D Sauer

    2014-01-01

    Video-gaming is a common pastime among adolescents, particularly adolescent males in industrialized nations. Despite widespread suggestions that video-gaming negatively affects academic achievement, the evidence is inconclusive. We reanalyzed data from over 192,000 students in 22 countries involved in the 2009 Programme for International Student Assessment (PISA) to estimate the true effect size of frequency of videogame use on adolescent academic achievement in science, mathematics and readi...

  15. Peer Victimisation and Depressive Symptoms: Can Specific Coping Strategies Buffer the Negative Impact of Cybervictimisation?

    Science.gov (United States)

    Machmutow, Katja; Perren, Sonja; Sticca, Fabio; Alsaker, Francoise D.

    2012-01-01

    This longitudinal study investigated whether cybervictimisation is an additional risk factor for depressive symptoms over and beyond traditional victimisation in adolescents. Furthermore, it explored whether certain coping strategies moderate the impact of cybervictimisation on depressive symptoms. A total of 765 Swiss seventh graders (mean age at…

  16. Similar negative impacts of temperature on global wheat yield estimated by three independent methods

    Science.gov (United States)

    The potential impact of global temperature change on global wheat production has recently been assessed with different methods, scaling and aggregation approaches. Here we show that grid-based simulations, point-based simulations, and statistical regressions produce similar estimates of temperature ...

  17. Attachment style impacts behavior and early oculomotor response to positive, but not negative, pictures.

    Science.gov (United States)

    Silva, Catarina; Chaminade, Thierry; David, Da Fonseca; Santos, Andreia; Esteves, Francisco; Soares, Isabel; Deruelle, Christine

    2015-06-01

    The present study investigated whether oculomotor behavior is influenced by attachment styles. The Relationship Scales Questionnaire was used to assess attachment styles of forty-eight voluntary university students and to classify them into attachment groups (secure, preoccupied, fearful, and dismissing). Eye-tracking was recorded while participants engaged in a 3-seconds free visual exploration of stimuli presenting either a positive or a negative picture together with a neutral picture, all depicting social interactions. The task consisted in identifying whether the two pictures depicted the same emotion. Results showed that the processing of negative pictures was impermeable to attachment style, while the processing of positive pictures was significantly influenced by individual differences in insecure attachment. The groups highly avoidant regarding to attachment (dismissing and fearful) showed reduced accuracy, suggesting a higher threshold for recognizing positive emotions compared to the secure group. The groups with higher attachment anxiety (preoccupied and fearful) showed differences in automatic capture of attention, in particular an increased delay preceding the first fixation to a picture of positive emotional valence. Despite lenient statistical thresholds induced by the limited sample size of some groups (p emotions is affected by attachment styles. These results are discussed within a broader evolutionary framework. PMID:25693911

  18. Negative Impacts of Emerging Informal Groundwater Markets in Peninsular India: Reduced Local Food Security and Unemployment

    OpenAIRE

    H. Diwakara; Nagaraj, N.

    2003-01-01

    In peninsular India, water remains an extremely critical and valuable resource because of its scarcity. Being a semiarid region, demand for irrigation water competes with increasing demands from other sectors such as domestic and industrial uses. This paper analyses the impact of groundwater transfer from rural to urban areas on local food security and employment. We argue that groundwater trading from peri-urban to urban centres has led to ‘overdraft of groundwater,’ inflicting damage to the...

  19. Consequences of teenage parenthood: pathways which minimise the long term negative impacts of teenage childbearing

    OpenAIRE

    Berrington, Ann; Diamond, Ian; Ingham, Roger; Stevenson, Jim; Borgoni, Riccardo; Cobos Hernández, M. Isabel; Peter W.F. Smith

    2005-01-01

    This project was one of a programme of nine jointly funded by the Teenage Pregnancy Unit and the Policy Research Programme, Department of Health. The study used data from two large longitudinal cohort surveys (Avon Longitudinal Study of Parents And Children (ALSPAC) and the 1970 British Birth Cohort Study (BCS70)) to explore aspects of teenage parenthood and its impact for mothers, fathers and their children.

  20. Nostalgia buffers the negative impact of low procedural injustice on cooperation

    OpenAIRE

    Van Dijke, M.; Wildschut, Tim; Leunissen, J.M.; Sedikides, Constantine

    2015-01-01

    This research integrates the discrete emotion of nostalgia (a sentimental longing for the past) with relational models of procedural justice. An organizational survey and four experiments demonstrated that nostalgia buffers (i.e., weakens) the deleterious impact of low (compared to high) procedural justice on organizational citizenship behavior (OCB) and cooperation with authorities. Low procedural justice undermined social connectedness with authorities, and nostalgia’s buffering role derive...

  1. Impact of Negative Quality Inconsistency on Brand Loyalty – Case of Croatian Food Market

    OpenAIRE

    Martina Ferenčić; Ana Wölfling

    2015-01-01

    Attracting and keeping consumers’ loyalty in Fast Moving Consumer Goods segment became the main concern for all producing companies and retailers, too. Many marketing researchers argue that product or service quality perception is one of the key elements in brand loyalty building process. When talking about food market, one has to be aware that food consumption has direct impact on human health and, in that context, process of building brand loyalty for food brands is not possible, or it can ...

  2. Negative Impacts of Human Land Use on Dung Beetle Functional Diversity

    OpenAIRE

    Barragán, Felipe; Moreno, Claudia E.; Escobar, Federico; Gonzalo HALFFTER; Navarrete, Dario

    2011-01-01

    The loss of biodiversity caused by human activity is assumed to alter ecosystem functioning. However our understanding of the magnitude of the effect of these changes on functional diversity and their impact on the dynamics of ecological processes is still limited. We analyzed the functional diversity of copro-necrophagous beetles under different conditions of land use in three Mexican biosphere reserves. In Montes Azules pastures, forest fragments and continuous rainforest were analyzed, in ...

  3. Impact of electric field on Hofmeister effects in aggregation of negatively charged colloidal minerals

    Indian Academy of Sciences (India)

    Ying Tang; Hang Li; Hualing Zhu; Rui Tian; Xiaodan Gao

    2016-01-01

    In this study, the aggregation kinetics of negatively charged colloidal minerals in Na+, K+, NH+4 , Mg2+, Ca2+ and Cu2+ solutions were measured and Hofmeister effects therein were estimated through total average aggregation (TAA) rates and critical coagulation concentration (CCC). Hofmeister effects of TAA rates increased exponentially with the increase in electric field strength, which cannot be explained by the classical theories (i.e., ionic size, hydration and dispersion forces), indicating strong electric field at colloidal surface was an indispensable factor in studying Hofmeister effects. Meanwhile, Hofmeister series of CCC values Na+ > K+ > NH+4 > Mg2+ > Ca2+ > Cu2+ show fine correlation with the polarization of various cations, implying that onic polarization in strong electric field would be responsible for Hofmeister effects in aggregation of colloidal minerals, and the deduction was confirmed by the calculated results of electrostatic interactions between colloidal minerals.

  4. Enhanced interannual precipitation variability increases plant functional diversity that in turn ameliorates negative impact on productivity.

    Science.gov (United States)

    Gherardi, Laureano A; Sala, Osvaldo E

    2015-12-01

    Although precipitation interannual variability is projected to increase due to climate change, effects of changes in precipitation variance have received considerable less attention than effects of changes in the mean state of climate. Interannual precipitation variability effects on functional diversity and its consequences for ecosystem functioning are assessed here using a 6-year rainfall manipulation experiment. Five precipitation treatments were switched annually resulting in increased levels of precipitation variability while maintaining average precipitation constant. Functional diversity showed a positive response to increased variability due to increased evenness. Dominant grasses decreased and rare plant functional types increased in abundance because grasses showed a hump-shaped response to precipitation with a maximum around modal precipitation, whereas rare species peaked at high precipitation values. Increased functional diversity ameliorated negative effects of precipitation variability on primary production. Rare species buffered the effect of precipitation variability on the variability in total productivity because their variance decreases with increasing precipitation variance. PMID:26437913

  5. The negative impact of intentionally introduced Quercus rubra L. on a forest community

    Directory of Open Access Journals (Sweden)

    Beata Woziwoda

    2014-03-01

    Full Text Available Some alien woody species used in commercial forestry become invasive and, as invaders, cause major problems in natural and semi-natural ecosystems. However, the deliberate introduction of aliens can bring unintended negative changes also within areas of their cultivation. This paper presents the effects of the intentional introduction of the North-American Quercus rubra in European mixed Scots pine-Pedunculate oak forests (POFs: Querco roboris-Pinetum (W. Mat. 1981 J. Mat. 1988. Phytosociological data from field research combined with GIS data analysis of the current distribution of Northern Red oak in the studied habitat were used to determine the composition and structure of forest communities in plots with and without Q. rubra participation.  The results show that Q. rubra significantly reduces native species richness and abundance, both in old-growth and in secondary (post-agricultural forests. Not one resident vascular plant benefits from the introduction of Northern Red oak and only a few are able to tolerate its co-occurrence. The natural restocking of all native woody species is also strongly limited by this alien tree.  The introduction of Northern Red oak significantly limits the environmental functions of the POF ecosystem and weakens its economic and social aspects. However, its further cultivation is justified from an economic point of view, as the essential function of the studied forests is commercial timber production, and the introduction of this fast growing alien tree supports the provisioning ecosystem services. A clear description of the level of trade-off between the accepted negative and positive effects of the introduction of Q. rubra on forest ecosystem services requires further interdisciplinary studies.

  6. The Negative Impact of Stark Law Exemptions on Graduate Medical Education and Health Care Costs: The Example of Radiation Oncology

    International Nuclear Information System (INIS)

    Purpose: To survey radiation oncology training programs to determine the impact of ownership of radiation oncology facilities by non-radiation oncologists on these training programs and to place these findings in a health policy context based on data from the literature. Methods and Materials: A survey was designed and e-mailed to directors of all 81 U.S. radiation oncology training programs in this country. Also, the medical and health economic literature was reviewed to determine the impact that ownership of radiation oncology facilities by non-radiation oncologists may have on patient care and health care costs. Prostate cancer treatment is used to illustrate the primary findings. Results: Seventy-three percent of the surveyed programs responded. Ownership of radiation oncology facilities by non-radiation oncologists is a widespread phenomenon. More than 50% of survey respondents reported the existence of these arrangements in their communities, with a resultant reduction in patient volumes 87% of the time. Twenty-seven percent of programs in communities with these business arrangements reported a negative impact on residency training as a result of decreased referrals to their centers. Furthermore, the literature suggests that ownership of radiation oncology facilities by non-radiation oncologists is associated with both increased utilization and increased costs but is not associated with increased access to services in traditionally underserved areas. Conclusions: Ownership of radiation oncology facilities by non-radiation oncologists appears to have a negative impact on residency training by shifting patients away from training programs and into community practices. In addition, the literature supports the conclusion that self-referral results in overutilization of expensive services without benefit to patients. As a result of these findings, recommendations are made to study further how physician ownership of radiation oncology facilities influence graduate

  7. Life cycle assessment as a method of limitation of a negative environment impact of castings

    Directory of Open Access Journals (Sweden)

    M. Holtzer

    2011-07-01

    Full Text Available Casting production constitutes environmental problems going far beyond the foundry plant area. Applying a notion of the life cycle the input (suppliers side and output factors (clients side can be identified. The foundry plant activities for the environment hazard mitigation can be situated on various stages of the casting life cycle. The environment impact of motorisation castings made of different materials – during the whole life cycle of castings – are discussed in the paper. It starts from the charge material production, then follows via the casting process, car assembly, car exploitation and ends at the car breaking up for scrap.

  8. Low level off-road vehicle (ORV) traffic negatively impacts macroinvertebrate assemblages at sandy beaches in south-western Australia

    Science.gov (United States)

    Davies, Rebecca; Speldewinde, Peter C.; Stewart, Barbara A.

    2016-01-01

    Off-road vehicle use is arguably one of the most environmentally damaging human activities undertaken on sandy beaches worldwide. Existing studies focused on areas of high traffic volumes have demonstrated significantly lower abundance, diversity and species richness of fauna in zones where traffic is concentrated. The impact of lower traffic volumes is unknown. This study aimed to investigate the impacts of relatively low-level vehicle traffic on sandy beach fauna by sampling invertebrate communities at eight beaches located in south-western Australia. We found that even low-level vehicle traffic negatively impacts the physical beach environment, and consequently, the ability of many species to survive in this habitat in the face of this disturbance. Compaction, rutting and displacement of the sand matrix were observed over a large area, resulting in significant decreases in species diversity and density, and measurable shifts in community structure on beaches that experienced off-road vehicle traffic. Communities at impact sites did not display seasonal recovery as traffic was not significantly different between seasons. Given a choice between either reducing traffic volumes, or excluding ORV traffic from beaches, our results suggest that the latter would be more appropriate when the retention of ecological integrity is the objective. PMID:27121212

  9. Accepting multiple simultaneous liver offers does not negatively impact transplant outcomes.

    Science.gov (United States)

    Eldeen, Firas Zahr; Mourad, Moustafa Mabrouk; Bhandari, Mayank; Roll, Garrett; Gunson, Bridget; Mergental, Hynek; Bramhall, Simon; Isaac, John; Muiesan, Paolo; Mirza, Darius F; Perera, M Thamara P R

    2016-02-01

    Impact of performing multiple liver transplants (LT) in a short period of time is unknown. Consecutively performed LT potentially increase complication rates through team fatigue and overutilization of resources and increase ischemia time. We analyzed the impact of undertaking consecutive LT (Consecutive liver transplant, CLT; LT preceded by another transplant performed not more than 12 h before, both transplants grouped together) on outcomes. Of 1702 LT performed, 314 (18.4%) were CLT. Outcome data was compared with solitary LT (SLT; not more than one LT in 12-h period). Recipient, donor, and graft characteristics were evenly matched between SLT and CLT; second LT of CLT group utilized younger donors grafts with longer cold ischemic times (P = 0.015). Implantation and operative time were significantly lower in CLT recipients on intergroup analysis (P = 0.0001 and 0.002, respectively). Early hepatic artery thrombosis (E-HAT) was higher in CLT versus SLT (P = 0.038), despite absolute number of E-HAT being low in all groups. Intragroup analysis demonstrated a trend toward more frequent E-HAT in first LT, compared to subsequent transplants; however, difference did not reach statistical significance (P = 0.135). In era of organ scarcity, CLT performed at high-volume center is safe and allows pragmatic utilization of organs, potentially reducing number of discarded grafts and reducing waiting list mortality. PMID:26463509

  10. Swedish Upper Secondary School Students’ Conceptions of Negative Environmental Impact and Pricing

    Directory of Open Access Journals (Sweden)

    Cecilia Lundholm

    2013-03-01

    Full Text Available This study explores relationships between upper secondary school students’ understanding of prices and environmental impacts. The study uses responses from 110 students to problems in which they were asked to explain differences in prices and also to express and justify opinions on what should be the difference in prices. Very few students expressed an environmental dimension in their understanding of price. A few students suggested that environmental impact influenced price by raising demand for “Environmentally friendly products”. A few students suggested that ‘environmentally friendly products’ had higher prices because they were more costly to produce. We found no examples of students combining both lines of explanation. However, nearly half of the students believed that prices should reflect environmental effects, and this reasoning was divided between cases where the point was justified by a broad environmental motivation and cases where the point was justified in relation to incentives–to get consumers to act in a more environmentally friendly way.

  11. Negative Impacts of the Neo-liberal Policies on the Banking Sector in Bulgaria

    Directory of Open Access Journals (Sweden)

    Rossitsa Rangelova Pavlova

    2015-04-01

    Full Text Available From the beginning of the 1970s until the last global financial and economic crisis in 2008-2009, neo-liberal ideas guided economic policy development. It is worth noting that the Central and Eastern European countries transformed their economies from centrally planned to а market type at the peak of the liberal policies. Bulgaria offers a particularly interesting example because the country encountered a very difficult transition from one extreme of an economic system organization to another. The paper considers the reforms in the Bulgarian banking sector during the transition period from a centrally planned to a market type economy (from 1989 onward through the implementation of neo-liberal policies. The development of the banking sector and its transformation is analyzed throughout the two main periods: before and after the transition. The latter is divided into two sub-periods (phases beginning with the early 1990s, followed by the financial and bank crisis in the country, the introduction of a currency board regime in 1997, and stabilization, and ending with the global crisis in 2008-2009. This article summarizes that during the transition period, a modern banking system was established to accumulate profit rather than to promote economic growth. Following a chronological order, the negative effects of the liberalization of the Bulgarian banking sector are specified: the exportation of ownership (and control upon banking system assets, unfair asset redistribution, the emergence of the local oligarchy, the weak protection of the taxpayers and others.

  12. Impact of Triple-Negative Phenotype on Prognosis of Patients With Breast Cancer Brain Metastases

    International Nuclear Information System (INIS)

    Purpose: To elucidate survival times and identify potential prognostic factors in patients with triple-negative (TN) phenotype who harbored brain metastases arising from breast cancer and who underwent stereotactic radiosurgery (SRS). Methods and Materials: A total of 103 breast cancer patients with brain metastases were treated with SRS and then studied retrospectively. Twenty-four patients (23.3%) were TN. Survival times were estimated using the Kaplan-Meier method, with a log–rank test computing the survival time difference between groups. Univariate and multivariate analyses to predict potential prognostic factors were performed using a Cox proportional hazard regression model. Results: The presence of TN phenotype was associated with worse survival times, including overall survival after the diagnosis of primary breast cancer (43 months vs. 82 months), neurologic survival after the diagnosis of intracranial metastases, and radiosurgical survival after SRS, with median survival times being 13 months vs. 25 months and 6 months vs. 16 months, respectively (p < 0.002 in all three comparisons). On multivariate analysis, radiosurgical survival benefit was associated with non-TN status and lower recursive partitioning analysis class at the initial SRS. Conclusion: The TN phenotype represents a significant adverse prognostic factor with respect to overall survival, neurologic survival, and radiosurgical survival in breast cancer patients with intracranial metastasis. Recursive partitioning analysis class also served as an important and independent prognostic factor.

  13. Impact of Triple-Negative Phenotype on Prognosis of Patients With Breast Cancer Brain Metastases

    Energy Technology Data Exchange (ETDEWEB)

    Xu Zhiyuan [Department of Neurosurgery, University of Virginia, Charlottesville, Virginia (United States); Schlesinger, David [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia (United States); Toulmin, Sushila [Department of Neurosurgery, University of Virginia, Charlottesville, Virginia (United States); Rich, Tyvin [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia (United States); Sheehan, Jason, E-mail: jps2f@virginia.edu [Department of Neurosurgery, University of Virginia, Charlottesville, Virginia (United States)

    2012-11-01

    Purpose: To elucidate survival times and identify potential prognostic factors in patients with triple-negative (TN) phenotype who harbored brain metastases arising from breast cancer and who underwent stereotactic radiosurgery (SRS). Methods and Materials: A total of 103 breast cancer patients with brain metastases were treated with SRS and then studied retrospectively. Twenty-four patients (23.3%) were TN. Survival times were estimated using the Kaplan-Meier method, with a log-rank test computing the survival time difference between groups. Univariate and multivariate analyses to predict potential prognostic factors were performed using a Cox proportional hazard regression model. Results: The presence of TN phenotype was associated with worse survival times, including overall survival after the diagnosis of primary breast cancer (43 months vs. 82 months), neurologic survival after the diagnosis of intracranial metastases, and radiosurgical survival after SRS, with median survival times being 13 months vs. 25 months and 6 months vs. 16 months, respectively (p < 0.002 in all three comparisons). On multivariate analysis, radiosurgical survival benefit was associated with non-TN status and lower recursive partitioning analysis class at the initial SRS. Conclusion: The TN phenotype represents a significant adverse prognostic factor with respect to overall survival, neurologic survival, and radiosurgical survival in breast cancer patients with intracranial metastasis. Recursive partitioning analysis class also served as an important and independent prognostic factor.

  14. NEGATIVE AND POSITIVE IMPACTS OF THE OIL PRICE DECLINE ON THE EGYPTIAN ECONOMY

    Directory of Open Access Journals (Sweden)

    Fatima Ahmed Shafiq

    2015-12-01

    Full Text Available The study handled the negative effects of the decline in the prices of oil in Egypt. It aimed at identifying the influence of this fall on the different sectors of the country. The results showed that the total earnings of oil in the balanced budget of the year 2014/15 have reached LE. 110.81 billion or about 20% of the total earnings of the balanced budget. The study also showed that the most important reasons for the fall is the insistence of the oil exporting counties not to decrease the amounts of production despite the fall in prices. Consequently, this has led to the great increase in the demand of oil, the United States’ inclination towards producing rocky oil and increasing the production so that it reaches 4 million barrel per day. This fall in the prices could also be a political game against Russia, which produces 10 million barrel a day and mainly depends on exporting pure oil.

  15. Protein Tyrosine Phosphatase-1B Negatively Impacts Host Defense against Pseudomonas aeruginosa Infection.

    Science.gov (United States)

    Yue, Lei; Xie, Zhongping; Li, Hua; Pang, Zheng; Junkins, Robert D; Tremblay, Michel L; Chen, Xiaochun; Lin, Tong-Jun

    2016-05-01

    Pseudomonas aeruginosa is a major opportunistic pathogen in immune-compromised individuals. Mechanisms governing immune responses to P. aeruginosa infection remain incompletely defined. Herein, we demonstrate that protein tyrosine phosphatase-1B (PTP1B) is a critical negative regulator in P. aeruginosa infection. PTP1B-deficient mice display greatly enhanced bacterial clearance and reduced disease scores, which are accompanied by increased neutrophil infiltration and cytokine production. Interestingly, PTP1B deficiency mainly up-regulates the production of interferon-stimulated response elements-regulated cytokines and chemokines, including chemokine ligand 5 (regulated on activation normal T cell expressed and secreted), CXCL10 (interferon γ-inducible protein 10), and interferon-β production. Further studies reveal that PTP1B deficiency leads to increased interferon regulatory factor 7 (IRF7) expression and activation. These findings demonstrate a novel regulatory mechanism of the immune response to P. aeruginosa infection through PTP1B-IRF7 interaction. This novel PTP1B-IRF7-interferon-stimulated response elements pathway may have broader implications in Toll-like receptor-mediated innate immunity. PMID:27105736

  16. Behavioral Symptoms in Motor Neuron Disease and Their Negative Impact on Caregiver Burden

    Institute of Scientific and Technical Information of China (English)

    Bo Cui; Li-Ying Cui; Ming-Sheng Liu; Xiao-Guang Li; Jun-Fang Ma; Jia Fang; Qing-Yun Ding

    2015-01-01

    Background:The spectrum of abnormal behaviors in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) has been described,but its practical meaning,namely its impact on caregiver burden,has not been clearly documented in Chinese population.This study aimed to assess the distribution of abnormal behaviors in Chinese population,and to analyze the relationship between behavior changes and caregiver burden.Methods:Sixty-five patients with ALS/MND have been consecutively enrolled into registry platform of Peking Union Medical College Hospital.An investigation was performed to these patients and their caregivers using the revised ALS function rating scale,Frontal Behavioral Inventory-ALS version,the Frontal Assessment Battery,and the Caregiver Burden Inventory.Results:Twenty-eight (43.1%) patients displayed abnormal behaviors of varying degrees,with one fulfilling the diagnostic criteria of frontotemporal lobe degeneration.Irritability,logopenia,and inflexibility ranked top 3 of abnormal behavior list.Correlation analysis revealed that the degree of behavioral change and frontal cognitive status were significantly associated with caregiver burden,with more extensive impact from disinhibitive behaviors.Analysis of covariance analysis showed that after associated factors were corrected,caregivers of patients with moderate to severe behavior change reported significantly heavier developmental burden,physical burden,and total burden than those with no behavioral change.Conclusions:Neurobehavioral symptoms could present in around 40% of Chinese patients with ALS/MND,and the distribution of these behaviors was also unique.Besides,abnormal behaviors were highly related to caregivers' burden.

  17. Conversion of sagebrush shrublands to exotic annual grasslands negatively impacts small mammal communities

    Science.gov (United States)

    Ostoja, S.M.; Schupp, E.W.

    2009-01-01

    Aim The exotic annual cheatgrass (Bromus tectorum) is fast replacing sagebrush (Artemisia tridentata) communities throughout the Great Basin Desert and nearby regions in the Western United States, impacting native plant communities and altering fire regimes, which contributes to the long-term persistence of this weedy species. The effect of this conversion on native faunal communities remains largely unexamined. We assess the impact of conversion from native perennial to exotic annual plant communities on desert rodent communities. Location Wyoming big sagebrush shrublands and nearby sites previously converted to cheatgrass-dominated annual grasslands in the Great Basin Desert, Utah, USA. Methods At two sites in Tooele County, Utah, USA, we investigated with Sherman live trapping whether intact sagebrush vegetation and nearby converted Bromus tectorum-dominated vegetation differed in rodent abundance, diversity and community composition. Results Rodent abundance and species richness were considerably greater in sagebrush plots than in cheatgrass-dominated plots. Nine species were captured in sagebrush plots; five of these were also trapped in cheatgrass plots, all at lower abundances than in the sagebrush. In contrast, cheatgrass-dominated plots had no species that were not found in sagebrush. In addition, the site that had been converted to cheatgrass longer had lower abundances of rodents than the site more recently converted to cheatgrass-dominated plots. Despite large differences in abundances and species richness, Simpson's D diversity and Shannon-Wiener diversity and Brillouin evenness indices did not differ between sagebrush and cheatgrass-dominated plots. Main conclusions This survey of rodent communities in native sagebrush and in converted cheatgrass-dominated vegetation suggests that the abundances and community composition of rodents may be shifting, potentially at the larger spatial scale of the entire Great Basin, where cheatgrass continues to invade

  18. Eyewitness memory: The impact of a negative mood during encoding and/or retrieval upon recall of a non-emotive event.

    Science.gov (United States)

    Thorley, Craig; Dewhurst, Stephen A; Abel, Joseph W; Knott, Lauren M

    2016-07-01

    The police often appeal for eyewitnesses to events that were unlikely to have been emotive when observed. An eyewitness, however, may be in a negative mood whilst encoding or retrieving such events as mood can be influenced by a range of personal, social, and environmental factors. For example, bad weather can induce a negative mood. This experiment compared the impact of negative and neutral moods during encoding and/or retrieval upon eyewitness recall of a non-emotive event. A negative mood during encoding had no impact upon the number of correct details recalled (provided participants were in a neutral mood at retrieval) but a negative mood during retrieval impaired the number of correct details recalled (provided participants were in a neutral mood at encoding). A negative mood at both time points enhanced the number of correct details recalled, demonstrating a mood-dependent memory enhancement. The forensic implications of these findings are discussed. PMID:26273852

  19. Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness

    Science.gov (United States)

    Villanueva, Eneko; Martí-Solano, Maria; Fillat, Cristina

    2016-06-01

    Codon usage adaptation of lytic viruses to their hosts is determinant for viral fitness. In this work, we analyzed the codon usage of adenoviral proteins by principal component analysis and assessed their codon adaptation to the host. We observed a general clustering of adenoviral proteins according to their function. However, there was a significant variation in the codon preference between the host-interacting fiber protein and the rest of structural late phase proteins, with a non-optimal codon usage of the fiber. To understand the impact of codon bias in the fiber, we optimized the Adenovirus-5 fiber to the codon usage of the hexon structural protein. The optimized fiber displayed increased expression in a non-viral context. However, infection with adenoviruses containing the optimized fiber resulted in decreased expression of the fiber and of wild-type structural proteins. Consequently, this led to a drastic reduction in viral release. The insertion of an exogenous optimized protein as a late gene in the adenovirus with the optimized fiber further interfered with viral fitness. These results highlight the importance of balancing codon usage in viral proteins to adequately exploit cellular resources for efficient infection and open new opportunities to regulate viral fitness for virotherapy and vaccine development.

  20. Nutritional Solutions to Reduce Risks of Negative Health Impacts of Air Pollution.

    Science.gov (United States)

    Péter, Szabolcs; Holguin, Fernando; Wood, Lisa G; Clougherty, Jane E; Raederstorff, Daniel; Antal, Magda; Weber, Peter; Eggersdorfer, Manfred

    2015-12-01

    Air pollution worldwide has been associated with cardiovascular and respiratory morbidity and mortality, particularly in urban settings with elevated concentrations of primary pollutants. Air pollution is a very complex mixture of primary and secondary gases and particles, and its potential to cause harm can depend on multiple factors-including physical and chemical characteristics of pollutants, which varies with fine-scale location (e.g., by proximity to local emission sources)-as well as local meteorology, topography, and population susceptibility. It has been hypothesized that the intake of anti-oxidant and anti-inflammatory nutrients may ameliorate various respiratory and cardiovascular effects of air pollution through reductions in oxidative stress and inflammation. To date, several studies have suggested that some harmful effects of air pollution may be modified by intake of essential micronutrients (such as B vitamins, and vitamins C, D, and E) and long-chain polyunsaturated fatty acids. Here, we review the existing literature related to the potential for nutrition to modify the health impacts of air pollution, and offer a framework for examining these interactions. PMID:26690474

  1. The creation of special economic zones in China: Positive and negative impacts in its implementation

    Directory of Open Access Journals (Sweden)

    José Manuel Orozco Plascencia

    2011-08-01

    Full Text Available At the end of seventies, Deng Xioaping, President applied a modernization policy in China, that during more than 30 years allow to reach high economic growth rates above 8% average per year. This reform included the instauration of four Special Economic Zones (SEZ in the southeast of the country, three in Guangdong (Shenzhen, Zhuhai and Shantao and one in Xiamen, Fujian.The purpose of this paper is to analyze the backgrounds of SEZ, the reasons of Chinese Government to implement its and the positive impacts and barriers to become operational.The conclusion in this article is that sez arise like an experiment of the Chinese central government economic policy to apply capitalist measures in design previous regions, the most important benefit has been the strong attraction of Foreing Direct Investment, explained in a surplus trade balance, sustanaible economic growht and technological transference. However, the most significative operational barrier has been the legal rigidity in the imported overseas products, a change of nacional politicideology system and problem asociated with burocracy and corruption.

  2. Nutritional Solutions to Reduce Risks of Negative Health Impacts of Air Pollution

    Directory of Open Access Journals (Sweden)

    Szabolcs Péter

    2015-12-01

    Full Text Available Air pollution worldwide has been associated with cardiovascular and respiratory morbidity and mortality, particularly in urban settings with elevated concentrations of primary pollutants. Air pollution is a very complex mixture of primary and secondary gases and particles, and its potential to cause harm can depend on multiple factors—including physical and chemical characteristics of pollutants, which varies with fine-scale location (e.g., by proximity to local emission sources—as well as local meteorology, topography, and population susceptibility. It has been hypothesized that the intake of anti-oxidant and anti-inflammatory nutrients may ameliorate various respiratory and cardiovascular effects of air pollution through reductions in oxidative stress and inflammation. To date, several studies have suggested that some harmful effects of air pollution may be modified by intake of essential micronutrients (such as B vitamins, and vitamins C, D, and E and long-chain polyunsaturated fatty acids. Here, we review the existing literature related to the potential for nutrition to modify the health impacts of air pollution, and offer a framework for examining these interactions.

  3. Costly learning: preference for familiar food persists despite negative impact on survival.

    Science.gov (United States)

    Costa, Thaiany M; Hebets, Eileen A; Melo, Diogo; Willemart, Rodrigo H

    2016-07-01

    Animals often rely on events in their environment that provide information (i.e. experience) to alter their future decision-making in ways that are presumed to be beneficial. Such experience-based learning, however, does not always lead to adaptive decision-making. In this study, we use the omnivorous harvestman Heteromitobates discolor to explore the role of past diet on subsequent food choice and survival. We first tested whether a short-term homogeneous diet (rotten crickets, fresh crickets or dog food) influenced subsequent food choice (rotten cricket versus fresh cricket). We next examine the impact of diet on survival. We found that following experience with a homogeneous cricket diet, adult harvestmen displayed a learned preference for familiar food, regardless of whether it was rotten or fresh crickets; individuals experiencing dog food were equally likely to choose rotten versus fresh crickets. We additionally found that individuals that ate rotten crickets suffered shorter survival than those that ate fresh crickets. Together, our results suggest that the diet an individual experiences can lead to maladaptive food preferences-preferences that ultimately result in reduced longevity. PMID:27405381

  4. Genetically-Improved Tilapia Strains in Africa: Potential Benefits and Negative Impacts

    Directory of Open Access Journals (Sweden)

    Yaw B. Ansah

    2014-06-01

    Full Text Available Two genetically improved tilapia strains (GIFT and Akosombo have been created with Oreochromis niloticus (Nile tilapia, which is native to Africa. In particular, GIFT has been shown to be significantly superior to local African tilapia strains in terms of growth rate. While development economists see the potential for food security and poverty reduction in Africa from culture of these new strains of tilapia, conservationists are wary of potential ecological and genetic impacts on receiving ecosystems and native stocks of tilapia. This study reviews the history of the GIFT technology, and identifies potential environmental and genetic risks of improved and farmed strains and tilapia in general. We also estimate the potential economic gains from the introduction of genetically improved strains in Africa, using Ghana as a case country. Employing a combination of the Economic-Surplus model and Monte Carlo simulation, we found the mean net present value (NPV of the introduction of the GIFT strain in Ghana to be approximately 1% of the country’s gross domestic product. Sensitivity analysis indicated that the difference in growth or yield between the GIFT and locally-available strains has the largest effect on mean NPV. We conclude that improvements in management practices and infrastructure could increase the yield and profitability of the local strains even if genetically-improved strains are not introduced. These improvements also will ensure the realization of the full potential of introduced strains.

  5. How electromagnetic fields can influence adult stem cells: positive and negative impacts.

    Science.gov (United States)

    Maziarz, Aleksandra; Kocan, Beata; Bester, Mariusz; Budzik, Sylwia; Cholewa, Marian; Ochiya, Takahiro; Banas, Agnieszka

    2016-01-01

    The electromagnetic field (EMF) has a great impact on our body. It has been successfully used in physiotherapy for the treatment of bone disorders and osteoarthritis, as well as for cartilage regeneration or pain reduction. Recently, EMFs have also been applied in in vitro experiments on cell/stem cell cultures. Stem cells reside in almost all tissues within the human body, where they exhibit various potential. These cells are of great importance because they control homeostasis, regeneration, and healing. Nevertheless, stem cells when become cancer stem cells, may influence the pathological condition. In this article we review the current knowledge on the effects of EMFs on human adult stem cell biology, such as proliferation, the cell cycle, or differentiation. We present the characteristics of the EMFs used in miscellaneous assays. Most research has so far been performed during osteogenic and chondrogenic differentiation of mesenchymal stem cells. It has been demonstrated that the effects of EMF stimulation depend on the intensity and frequency of the EMF and the time of exposure to it. However, other factors may affect these processes, such as growth factors, reactive oxygen species, and so forth. Exploration of this research area may enhance the development of EMF-based technologies used in medical applications and thereby improve stem cell-based therapy and tissue engineering. PMID:27086866

  6. The negative impacts of human activities in the eastern African region: an international waters perspective.

    Science.gov (United States)

    Payet, Rolph; Obura, David

    2004-02-01

    The complex interactions between human activities and the environment at the interface of land and water is analyzed with a focus on the Somali Current (East Africa), and Indian Ocean Island States, subregions of the Global International Waters Assessment (GIWA). These 2 subregions contain some of the world's richest ecosystems, including the high biodiversity forests of Madagascar and the diverse coastal habitats of the eastern African coast. These ecosystems support local communities and national and regional economies. Current and future degradation of these systems, from water basins to continental shelves, affects the livelihoods and sustainability of the countries in the region, and long-term efforts to reduce poverty. The assessments determined that pollution and climate change are the primary environmental and social concerns in the Islands of the Indian Ocean, while freshwater shortage and unsustainable exploitation of fisheries and other living resources are the primary environmental and social concerns in East Africa. The GIWA approach, through assessing root causes of environmental concerns, enables the development of policy approaches for mitigating environmental degradation. This paper explores policy frameworks for mitigating the impacts, and reducing the drivers, of 3 environmental concerns--freshwater shortage; solid waste pollution; and climate change--addressing social and institutional causes and effects, and linking the subregions to broad international frameworks. The common theme in all 3 case studies is the need to develop integrated ecosystem and international waters policies, and mechanisms to manage conflicting interests and to limit threats to natural processes. PMID:15083647

  7. Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness.

    Science.gov (United States)

    Villanueva, Eneko; Martí-Solano, Maria; Fillat, Cristina

    2016-01-01

    Codon usage adaptation of lytic viruses to their hosts is determinant for viral fitness. In this work, we analyzed the codon usage of adenoviral proteins by principal component analysis and assessed their codon adaptation to the host. We observed a general clustering of adenoviral proteins according to their function. However, there was a significant variation in the codon preference between the host-interacting fiber protein and the rest of structural late phase proteins, with a non-optimal codon usage of the fiber. To understand the impact of codon bias in the fiber, we optimized the Adenovirus-5 fiber to the codon usage of the hexon structural protein. The optimized fiber displayed increased expression in a non-viral context. However, infection with adenoviruses containing the optimized fiber resulted in decreased expression of the fiber and of wild-type structural proteins. Consequently, this led to a drastic reduction in viral release. The insertion of an exogenous optimized protein as a late gene in the adenovirus with the optimized fiber further interfered with viral fitness. These results highlight the importance of balancing codon usage in viral proteins to adequately exploit cellular resources for efficient infection and open new opportunities to regulate viral fitness for virotherapy and vaccine development. PMID:27278133

  8. Negative impacts of human land use on dung beetle functional diversity.

    Science.gov (United States)

    Barragán, Felipe; Moreno, Claudia E; Escobar, Federico; Halffter, Gonzalo; Navarrete, Dario

    2011-01-01

    The loss of biodiversity caused by human activity is assumed to alter ecosystem functioning. However our understanding of the magnitude of the effect of these changes on functional diversity and their impact on the dynamics of ecological processes is still limited. We analyzed the functional diversity of copro-necrophagous beetles under different conditions of land use in three Mexican biosphere reserves. In Montes Azules pastures, forest fragments and continuous rainforest were analyzed, in Los Tuxtlas rainforest fragments of different sizes were analyzed and in Barranca de Metztitlán two types of xerophile scrub with different degrees of disturbance from grazing were analyzed. We assigned dung beetle species to functional groups based on food relocation, beetle size, daily activity period and food preferences, and as measures of functional diversity we used estimates based on multivariate methods. In Montes Azules functional richness was lower in the pastures than in continuous rainforest and rainforest fragments, but fragments and continuous forest include functionally redundant species. In small rainforest fragments (Tuxtlas, dung beetle functional richness was lower than in large rainforest fragments (>20 ha). Functional evenness and functional dispersion did not vary among habitat types or fragment size in these reserves. In contrast, in Metztitlán, functional richness and functional dispersion were different among the vegetation types, but differences were not related to the degree of disturbance by grazing. More redundant species were found in submontane than in crassicaule scrub. For the first time, a decrease in the functional diversity in communities of copro-necrophagous beetles resulting from changes in land use is documented, the potential implications for ecosystem functioning are discussed and a series of variables that could improve the evaluation of functional diversity for this biological group is proposed. PMID:21448292

  9. Adaptive response and genomic instability: allosteric response of genome to negative impact

    International Nuclear Information System (INIS)

    Currently, there is an upsurge concern on the unique response of living cells to low dose ionizing radiation for its inconformity to the existing paradigm of the biological action of radiation and its impact on the current understanding of risk evaluation of health effect of radiation in our workplace and environment. For the allosteric response to have significance, the cells must have an excellent sensing mechanism to discriminate tolerable and intolerable signals. In a series of experiments with mammalian, including human, cells, we demonstrated a novel sensing and signaling mechanism in the low-dose irradiated cells that was mediated by a PKCα-p3BMAPK-PLCδ1 feedback regulatory loop. Upon irradiation, PKCα is immediately activated, which in turn activate p38MAPK. The activation of p38MAPK is feedbacked to the activation of PKCα via PLCδ1, which catalyzes the hydrolysis of PtdInsP2 to generate PKCα-directed second messengers DAG and lnsP3. At low doses, the PKCα and p38MAPK continue to be activated for long time through this feedback loop, but when the cells encounter the high dose (>10 cGy or equivalent), the feedback loop is immediately comes to shutdown by deprivation of PKCα protein, known as down-regulation of PKC signaling. Thus, PKCα plays a key role in the long lasting nature of adaptive response to low doses and a binary switch to the genomic instability by too much signals. Tumor suppressor protein, p53, is a downstream effecter

  10. Urban green spaces′ effectiveness as a psychological buffer for the negative health impact of noise pollution: A systematic review

    Directory of Open Access Journals (Sweden)

    Angel Mario Dzhambov

    2014-01-01

    Full Text Available Noise pollution is one of the four major pollutions in the world. Little evidence exists about the actual preventive benefits of psychological noise attenuation by urban green spaces, especially from the perspective of environmental medicine and, to the best of our knowledge, there is not a systematic analysis on this topic. The aim of this review was to systematically evaluate whether there is conclusive scientific evidence for the effectiveness of urban green spaces as a psychological buffer for the negative impact of noise pollution on human health and to promote an evidence-based approach toward this still growing environmental hazard. MEDLINE and EMBASE databases were searched for experimental and epidemiological studies published before June 04, 2013 in English and Spanish. Data was independently extracted in two step process by the authors. Due to the heterogeneity of the included studies qualitative assessment was performed. We found moderate evidence that the presence of vegetation can generally reduce the negative perception of noise (supported with an electroencephalogram test in one of the experimental studies; consistent with the data from two epidemiological studies; one experiment found no effect and one was inconclusive about the positive effect. This review fills a gap in the literature and could help researchers further clarify the proper implementation of urban green spaces as a psychological buffer in areas with population exposed to chronic noise pollution.

  11. Organizational Justice and Perceived Organizational Support: Impact on Negative Work-Home Interference and Well-being Outcomes

    Directory of Open Access Journals (Sweden)

    Audrey Babic

    2015-10-01

    Full Text Available It is well established that negative work-home interference (NegWHI impacts upon several work attitudes and behaviors. In the interests of both organizational effectiveness and employee well-being, it is important to identify concepts related to NegWHI and investigate their effects on well-being outcomes. This study examines the mediating role of (1 perceived organizational support (POS in the relationship between organizational justice (OJ and NegWHI; and (2 NegWHI in the relationships between POS and four well-being outcomes. A total of 509 employees of a Belgian hospital were surveyed. Data were analyzed using structural equation modeling and the bootstrapping method. Results showed that POS partially mediates the relationships between distributive and passive procedural justice and NegWHI, and fully mediates the relationship between the other justice dimensions and NegWHI. NegWHI partially mediates the relationships between POS and both job satisfaction and intention to quit, and fully mediates the relationship between POS and job strain. Furthermore, POS is positively related to job engagement. This study showed that organizations can help employees to better manage their work and family lives and reduce the impact of NegWHI by enhancing employees’ feeling that they are supported by their organization. In order to increase POS, organizations need to promote justice in the workplace.

  12. Strategies to Mitigate the Negative and Accentuate the Positive Impacts of International Service-Learning on Host Communities

    Directory of Open Access Journals (Sweden)

    Shari Galiardi

    2012-04-01

    Full Text Available International service-learning can have a transformative effect on student participants, but little research has been done on the impact of these experiences on host communities. The authors make the case that an emphasis on intentional personal, cultural, and group preparation is imperative to have the best possible impact on both the student and host community. Overarching strategies include: 1 preparing students for their experience prior to departure from both an individual and group development perspective; 2 designing reflection activities and discussions that include members of the host community; 3 facilitating open conversations about equitable relationships, international perspectives of Americans, and potential negative effects the group could have on the host community; 4 providing opportunities for post-travel dialogue and personal action plans for re-engaging with the local community upon return. The authors draw from both theoretical frameworks and many years of experience traveling abroad with students to underpin the strategies outlined in this article. KEYWORDSservice-learning; group development; international

  13. High water availability increases the negative impact of a native hemiparasite on its non-native host.

    Science.gov (United States)

    Cirocco, Robert M; Facelli, José M; Watling, Jennifer R

    2016-03-01

    Environmental factors alter the impacts of parasitic plants on their hosts. However, there have been no controlled studies on how water availability modulates stem hemiparasites' effects on hosts. A glasshouse experiment was conducted to investigate the association between the Australian native stem hemiparasite Cassytha pubescens and the introduced host Ulex europaeus under high (HW) and low (LW) water supply. Cassytha pubescens had a significant, negative effect on the total biomass of U. europaeus, which was more severe in HW than LW. Regardless of watering treatment, infection significantly decreased shoot and root biomass, nodule biomass, nodule biomass per unit root biomass, F v/F m, and nitrogen concentration of U. europaeus. Host spine sodium concentration significantly increased in response to infection in LW but not HW conditions. Host water potential was significantly higher in HW than in LW, which may have allowed the parasite to maintain higher stomatal conductances in HW. In support of this, the δ(13)C of the parasite was significantly lower in HW than in LW (and significantly higher than the host). C. pubescens also had significantly higher F v/F m and 66% higher biomass per unit host in the HW compared with the LW treatment. The data suggest that the enhanced performance of C. pubescens in HW resulted in higher parasite growth rates and thus a larger demand for resources from the host, leading to poorer host performance in HW compared with LW. C. pubescens should more negatively affect U. europaeus growth under wet conditions rather than under dry conditions in the field. PMID:26703920

  14. Coaching to vision versus coaching to improvement needs: a preliminary investigation on the differential impacts of fostering positive and negative emotion during real time executive coaching sessions

    OpenAIRE

    Howard, Anita R.

    2015-01-01

    Drawing on intentional change theory (ICT; Boyatzis, 2006), this study examined the differential impact of inducing coaching recipients’ vision/positive emotion versus improvement needs/negative emotion during real time executive coaching sessions. A core aim of the study was to empirically test two central ICT propositions on the effects of using the coached person’s Positive Emotional Attractor (vision/PEA) versus Negative Emotional Attractor (improvement needs/NEA) as the anchoring framewo...

  15. Impact of microbiology cascade reporting on antibiotic de-escalation in cefazolin-susceptible Gram-negative bacteremia.

    Science.gov (United States)

    Johnson, L S; Patel, D; King, E A; Maslow, J N

    2016-07-01

    Cascade reporting (CR) involves reporting the susceptibilities of broad-spectrum agents only when the organism is resistant to more narrow-spectrum agents. The purpose of this study is to evaluate the impact of CR on antibiotic de-escalation practices and to characterize the impact of CR on clinical outcomes. CR rules were implemented in the microbiology laboratory at Atlantic Health System (AHS) in June 2013. A retrospective chart review was conducted at two community teaching hospitals in adult patients who had a blood culture positive for a Gram-negative organism susceptible to cefazolin and who were empirically treated with broad-spectrum beta-lactam (BSBL) antibiotics. De-escalation practices were compared in the pre-CR (July 2012-December 2012) and post-CR (July 2013-December 2013) periods. The primary endpoint was the percentage of patients whose BSBL agent was de-escalated to agents listed on the post-CR antibiotic susceptibility report within 48 h of the final report. Secondary endpoints include the difference in pre-CR and post-CR periods in terms of hospital length of stay, in-hospital mortality, 30-day readmission, Clostridium difficile infections, and re-initiation of a BSBL agent within 7 days. A total of 73 patients were included; 31 in the pre-CR and 42 in the post-CR period. Patients had similar baseline characteristics. Therapy was de-escalated in 48 % of pre-CR vs 71 % of post-CR patients (p = 0.043). No significant differences were observed in secondary endpoints between patients in the pre-CR and post-CR periods. CR resulted in significant improvements in de-escalation practices without affecting safety outcomes. PMID:27130036

  16. Using Modified Sorbents for Reducing Negative Impact of Oil-Containing Industrial Wastes on Natural and Artificial Waterways

    Directory of Open Access Journals (Sweden)

    Ljudmila Anatolievna Marchenko

    2015-09-01

    Full Text Available The study is aimed at developing and using co-precipitated hydroxides (CPH of aluminum and magnesium as sorbents, in order to reduce the negative impact of oil-containing industrial wastes on natural and artificial waterways. A new method of synthesizing a modified sorbent has been developed, featuring high sorption capacity to a wide range of pollutants in low-acid, neutral, and low-alkaline environments, able to extract complex compounds. A possibility to use this sorbent has been shown, and its sorption capacity has been studied. Sorption parameters have been defined. It has been shown that the value of the maximum achievable concentration efficiency in extracting the said ions on a co-precipitated sorbent is about ten times higher than the corresponding values that characterize sorption on analogous sorbents. In performing analytical studies, standard methods were used, as well as modern methods of physical and chemical analysis: x-ray phase, x-ray fluorescent, atomic absorption, spectral, chemical, thin layer chromatography, and chromato-mass-spectrometry. The specific surface of the samples was defined by the temperature of nitrogen absorption, using the chromatographic method, followed by processing the obtained results using the Brunauer-Emmett-Teller method. Porosity was defined using mercury porometry. The performed research has made it possible to obtain new highly efficient sorbents and assess their economic efficiency. The performed research will make it possible to resolve ecological and social problems by preventing the damage caused by environmental pollution with anthropogenous wastes.

  17. Be kind to your eating disorder patients: The impact of positive and negative feedback on the explicit and implicit self-esteem of female patients with eating disorders

    NARCIS (Netherlands)

    Linden, J. van der; Kamphuis, J.H.; Slagmolen, C.J.J.; Wigboldus, D.H.J.; Pieters, G.; Probst, M.

    2009-01-01

    OBJECTIVE: Lack of self-esteem may play an important role in the development of eating disorders (ED). This study investigated the differential impact of positive and negative feedback on implicit and explicit self-esteem in women with an ED (N=25) as compared to women without an ED (N=29). METHOD:

  18. Reducing the negative human-health impacts of bioenergy crop emissions through region-specific crop selection

    International Nuclear Information System (INIS)

    An expected global increase in bioenergy-crop cultivation as an alternative to fossil fuels will have consequences on both global climate and local air quality through changes in biogenic emissions of volatile organic compounds (VOCs). While greenhouse gas emissions may be reduced through the substitution of next-generation bioenergy crops such as eucalyptus, giant reed, and switchgrass for fossil fuels, the choice of species has important ramifications for human health, potentially reducing the benefits of conversion due to increases in ozone (O3) and fine particulate matter (PM2.5) levels as a result of large changes in biogenic emissions. Using the Community Earth System Model we simulate the conversion of marginal and underutilized croplands worldwide to bioenergy crops under varying future anthropogenic emissions scenarios. A conservative global replacement using high VOC-emitting crop profiles leads to modeled population-weighted O3 increases of 5–27 ppb in India, 1–9 ppb in China, and 1–6 ppb in the United States, with peak PM2.5 increases of up to 2 μg m−3. We present a metric for the regional evaluation of candidate bioenergy crops, as well as results for the application of this metric to four representative emissions profiles using four replacement scales (10–100% maximum estimated available land). Finally, we assess the total health and climate impacts of biogenic emissions, finding that the negative consequences of using high-emitting crops could exceed 50% of the positive benefits of reduced fossil fuel emissions in value. (letter)

  19. Reducing the negative human-health impacts of bioenergy crop emissions through region-specific crop selection

    Science.gov (United States)

    Porter, William C.; Rosenstiel, Todd N.; Guenther, Alex; Lamarque, Jean-Francois; Barsanti, Kelley

    2015-05-01

    An expected global increase in bioenergy-crop cultivation as an alternative to fossil fuels will have consequences on both global climate and local air quality through changes in biogenic emissions of volatile organic compounds (VOCs). While greenhouse gas emissions may be reduced through the substitution of next-generation bioenergy crops such as eucalyptus, giant reed, and switchgrass for fossil fuels, the choice of species has important ramifications for human health, potentially reducing the benefits of conversion due to increases in ozone (O3) and fine particulate matter (PM2.5) levels as a result of large changes in biogenic emissions. Using the Community Earth System Model we simulate the conversion of marginal and underutilized croplands worldwide to bioenergy crops under varying future anthropogenic emissions scenarios. A conservative global replacement using high VOC-emitting crop profiles leads to modeled population-weighted O3 increases of 5-27 ppb in India, 1-9 ppb in China, and 1-6 ppb in the United States, with peak PM2.5 increases of up to 2 μg m-3. We present a metric for the regional evaluation of candidate bioenergy crops, as well as results for the application of this metric to four representative emissions profiles using four replacement scales (10-100% maximum estimated available land). Finally, we assess the total health and climate impacts of biogenic emissions, finding that the negative consequences of using high-emitting crops could exceed 50% of the positive benefits of reduced fossil fuel emissions in value.

  20. Impact of lower body negative pressure induced hypovolemia on peripheral venous pressure waveform parameters in healthy volunteers

    International Nuclear Information System (INIS)

    Lower body negative pressure (LBNP) creates a reversible hypovolemia by sequestrating blood volume in the lower extremities. This study sought to examine the impact of central hypovolemia on peripheral venous pressure (PVP) waveforms in spontaneously breathing subjects. With IRB approval, 11 healthy subjects underwent progressive LBNP (baseline, −30, −75, and −90 mmHg or until the subject became symptomatic). Each was monitored for heart rate (HR), finger arterial blood pressure (BP), a chest respiratory band and PVP waveforms which are generated from a transduced upper extremity intravenous site. The first subject was excluded from PVP analysis because of technical errors in collecting the venous pressure waveform. PVP waveforms were analyzed to determine venous pulse pressure, mean venous pressure, pulse width, maximum and minimum slope (time domain analysis) together with cardiac and respiratory modulations (frequency domain analysis). No changes of significance were found in the arterial BP values at −30 mmHg LBNP, while there were significant reductions in the PVP waveforms time domain parameters (except for 50% width of the respiration induced modulations) together with modulation of the PVP waveform at the cardiac frequency but not at the respiratory frequency. As the LBNP progressed, arterial systolic BP, mean BP and pulse pressure, PVP parameters and PVP cardiac modulation decreased significantly, while diastolic BP and HR increased significantly. Changes in hemodynamic and PVP waveform parameters reached a maximum during the symptomatic phase. During the recovery phase, there was a significant reduction in HR together with a significant increase in HR variability, mean PVP and PVP cardiac modulation. Thus, in response to mild hypovolemia induced by LBNP, changes in cardiac modulation and other PVP waveform parameters identified hypovolemia before detectable hemodynamic changes. (paper)

  1. Impact of negative emotion on the neural correlates of long-term recognition in younger and older adults

    Directory of Open Access Journals (Sweden)

    Grégoria eKalpouzos

    2012-09-01

    Full Text Available Some studies have suggested that the memory advantage for negative emotional information over neutral information (negativity effect is reduced in aging. Besides the fact that most findings are based on immediate retrieval, the neural underpinnings of long-term emotional memory in aging have so far not been investigated. To address these issues, we assessed recognition of neutral and negative scenes after one- and 3-week retention intervals in younger and older adults using fMRI. We further used an event-related design in order to disentangle successful, false and true recognition. This study revealed 4 key findings: 1 Increased retention interval induced an increased rate of false recognitions for negative scenes, cancelling out the negativity effect (present for hit rates only on discrimination in both younger and older adults; 2 In younger, but not older, adults, reduced activity of the medial temporal lobe was observed over time for neutral scenes, but not for negative scenes, where stable or increased activity was seen; 3 Engagement of amygdala was observed in older adults after a 3-week delay during successful recognition of negative scenes (hits versus misses in comparison with neutral scenes, which may indicate engagement of automatic processes, but engagement of ventrolateral prefrontal cortex was unrelated to amygdala activity and performance; and 4 After 3 weeks, but not after one week, true recognition of negative scenes was characterized by more activity in left hippocampus and lateral occipito-temporal regions (hits versus false alarms. As these regions are known to be related to consolidation mechanisms, the observed pattern may indicate the presence of delayed consolidation of true memories. Nonetheless, older adults’ low performance in discrimination of negative scenes could reflect the fact that overall, after long delays of retention, they rely more on general information rather than on perceptual detail in making

  2. The meaning of collective terrorist threat : Understanding the subjective causes of terrorism reduces its negative psychological impact

    NARCIS (Netherlands)

    Fischer, Peter; Postmes, Tom; Koeppl, Julia; Conway, Lianne; Fredriksson, Tom

    2011-01-01

    This article hypothesized that the possibility to construct intellectual meaning of a terrorist attack (i.e., whether participants can cognitively understand why the perpetrators did their crime) reduces the negative psychological consequences typically associated with increased terrorist threat. Co

  3. Prognostic impact of clinicopathologic parameters in stage II/III breast cancer treated with neoadjuvant docetaxel and doxorubicin chemotherapy: paradoxical features of the triple negative breast cancer

    Directory of Open Access Journals (Sweden)

    Kim Dong-Wan

    2007-11-01

    Full Text Available Abstract Background Prognostic factors in locally advanced breast cancer treated with neoadjuvant chemotherapy differ from those of early breast cancer. The purpose of this study was to identify the clinical significance of potential predictive and prognostic factors in breast cancer patients treated by neoadjuvant chemotherapy. Methods A total of 145 stage II and III breast cancer patients received neoadjuvant docetaxel/doxorubicin chemotherapy were enrolled in this study. We examined the clinical and biological factors (ER, PR, p53, c-erbB2, bcl-2, and Ki-67 by immunohistochemistry. We analyzed clinical outcome and their correlation with clinicopathologic parameters. Results Among the clinicopathologic parameters investigated, none of the marker was correlated with response rate (RR except triple negative phenotype. Patients with triple negative phenotype showed higher RR (83.0% in triple negative vs. 62.2% in non-triple negative, p = 0.012 and pathologic complete RR (17.0% in triple negative vs. 3.1% in non-triple negative, p = 0.005. However, relapse free survival (RFS and overall survival (OS were significantly shorter in triple negative breast cancer patients (p p = 0.021, respectively. Low histologic grade, positive hormone receptors, positive bcl-2 and low level of Ki-67 were associated with prolonged RFS. In addition, positive ER and positive bcl-2 were associated with prolonged OS. In our homogeneous patient population, initial clinical stage reflects RFS and OS more precisely than pathologic stage. In multivariate analysis, initial clinical stage was the only significant independent prognostic factor to impact on OS (hazard ratio 3.597, p = 0.044. Conclusion Several molecular markers provided useful predictive and prognostic information in stage II and III breast cancer patients treated with neoadjuvant docetaxel/doxorubicin chemotherapy. Triple negative phenotype was associated with shorter survival, even though it was associated

  4. 母语负迁移对英语教学的影响及应对策略%Impact of Negative Transfer to English Teaching and Strategies

    Institute of Scientific and Technical Information of China (English)

    郭妍

    2014-01-01

    Negative transfer exists in students' English learning process, and has played a negative impact to some extent. In this paper, pronunciation, vocabulary, grammar, three levels of analysis of the causes and forms of negative migration, and ultimately come to effective coping strategies.%母语负迁移时刻存在于学生英语学习过程中,并且一定程度上起到消极的影响。本文针对语音、词汇、语法三个层面分析了母语负迁移的成因和形式,并最终得出行之有效的应对策略。

  5. Creativity as an Attribute of Positive Psychology: The Impact of Positive and Negative Affect on the Creative Personality

    Science.gov (United States)

    Charyton, Christine; Hutchison, Shannon; Snow, Lindsay; Rahman, Mohammed A.; Elliott, John O.

    2009-01-01

    Positive psychology explores how optimism can lead to health, happiness, and creativity. However, questions remain as to how affective states influence creativity. Data on creative personality, optimism, pessimism, positive and negative affect, and current and usual happiness ratings were collected on 161 college students enrolled in an…

  6. Reactions to perceived fairness: The impact of mortality salience and self-esteem on ratings of negative affect

    NARCIS (Netherlands)

    Bos, K. van den

    2001-01-01

    In correspondence with terror management theory, the findings of two experiments show that reminders of death lead to stronger effects of perceived fairness on ratings of negative affect. Furthermore, in line with the theory''s self-esteem mechanism, results of Experiment 1 suggest that state self-e

  7. Strategies to Mitigate the Negative and Accentuate the Positive Impacts of International Service-Learning on Host Communities

    OpenAIRE

    Shari Galiardi; Jenny Koehn

    2012-01-01

    International service-learning can have a transformative effect on student participants, but little research has been done on the impact of these experiences on host communities. The authors make the case that an emphasis on intentional personal, cultural, and group preparation is imperative to have the best possible impact on both the student and host community. Overarching strategies include: 1) preparing students for their experience prior to departure from both an individual and group dev...

  8. Impact of restriction of cefepime use on the antimicrobial susceptibility of Gram-negative bacilli related to healthcare-associated infections in an orthopedic hospital

    Directory of Open Access Journals (Sweden)

    Rossi F

    2011-08-01

    Full Text Available Priscila R Oliveira1, Adriana P Paula1, Karine Dal-Paz1, Cassia S Felix1, Flavia Rossi2, Jorge S Silva1, Ana Lucia M Lima11Orthopaedics and Traumatology Department, 2Pathology Department, University of São Paulo, São Paulo, BrazilIntroduction: In recent decades, antimicrobial resistance has become a public health problem, particularly in cases of healthcare-associated infections. Interaction between antibiotic consumption and resistance development is of particular interest regarding Gram-negative bacilli, whose growing resistance has represented a great challenge.Objective: Assess the impact of restriction of cefepime use on antimicrobial susceptibility among the Gram-negative bacilli (GNB most frequently involved in healthcare-associated infections (HAI.Methods: Data relating to hospital occupancy and mortality rates, incidence of HAI, incidence of GNB as causative agents of HAI, antimicrobial consumption at the hospital and antimicrobial susceptibility of GNB related to HAI were compared between two periods: a 24-month period preceding restriction of cefepime use and a 24-month period subsequent to this restriction.Results: There was a significant drop in cefepime consumption after its restriction. Susceptibility of Acinetobacter baumanii improved relating to gentamicin, but it worsened in relation to imipenem, subsequent to this restriction. For Pseudomonas aeruginosa, there was no change in antimicrobial susceptibility. For Klebsiella pneumoniae and Enterobacter spp, there were improvements in susceptibility relating to ciprofloxacin.Conclusion: Restriction of cefepime use had a positive impact on K. pneumoniae and Enterobacter spp, given that after this restriction, their susceptibilities to ciprofloxacin improved. However, for A. baumanii, the impact was negative, given the worsening of susceptibility to imipenem.Keywords: ecological studies, cross infection, drug resistance, microbial, Gram-negative bacilli, cefepime

  9. Canine Comfort: Pet Affinity Buffers the Negative Impact of Ambivalence over Emotional Expression on Perceived Social Support

    OpenAIRE

    Bryan, Jennifer L.; Quist, Michelle C.; Young, Chelsie M.; Steers, Mai-Ly N.; Foster, Dawn W.; Lu, Qian

    2014-01-01

    This study evaluated pet affinity as a buffer between ambivalence over emotional expression (AEE) and social support. AEE occurs when one desires to express emotions but is reluctant to do so and is related to negative psychological outcomes. Individuals high in AEE may have difficulty receiving social support and thus may not gain accompanying benefits. Social support has been associated with positive health outcomes, and pet support is positively associated with human social support. The pr...

  10. A Consumer Perspective of the Impact of Corporate Social Responsibility (CSR) Efforts and Negative Externalities on Brand Image

    OpenAIRE

    Wahyudi, Diana Rikasari

    2007-01-01

    Nowadays, companies are increasing their participation towards the implementation of Corporate Social Responsibility (CSR) to help build, and in some cases, repair their brand images. Companies market their CSR initiatives to the public in general and consumers in particular, in hopes that such efforts will result in a higher degree of positive reception from the public and consumers. On the other hand, there exist external parties which equally attempt to expose negative information about co...

  11. The warmer the weather, the more gram-negative bacteria - impact of temperature on clinical isolates in intensive care units.

    Directory of Open Access Journals (Sweden)

    Frank Schwab

    Full Text Available BACKGROUND: We investigated the relationship between average monthly temperature and the most common clinical pathogens causing infections in intensive care patients. METHODS: A prospective unit-based study in 73 German intensive care units located in 41 different hospitals and 31 different cities with total 188,949 pathogen isolates (102,377 Gram-positives and 86,572 Gram-negatives from 2001 to 2012. We estimated the relationship between the number of clinical pathogens per month and the average temperature in the month of isolation and in the month prior to isolation while adjusting for confounders and long-term trends using time series analysis. Adjusted incidence rate ratios for temperature parameters were estimated based on generalized estimating equation models which account for clustering effects. RESULTS: The incidence density of Gram-negative pathogens was 15% (IRR 1.15, 95%CI 1.10-1.21 higher at temperatures ≥ 20°C than at temperatures below 5°C. E. cloacae occurred 43% (IRR=1.43; 95%CI 1.31-1.56 more frequently at high temperatures, A. baumannii 37% (IRR=1.37; 95%CI 1.11-1.69, S. maltophilia 32% (IRR=1.32; 95%CI 1.12-1.57, K. pneumoniae 26% (IRR=1.26; 95%CI 1.13-1.39, Citrobacter spp. 19% (IRR=1.19; 95%CI 0.99-1.44 and coagulase-negative staphylococci 13% (IRR=1.13; 95%CI 1.04-1.22. By contrast, S. pneumoniae 35% (IRR=0.65; 95%CI 0.50-0.84 less frequently isolated at high temperatures. For each 5°C increase, we observed a 3% (IRR=1.03; 95%CI 1.02-1.04 increase of Gram-negative pathogens. This increase was highest for A. baumannii with 8% (IRR=1.08; 95%CI 1.05-1.12 followed by K. pneumoniae, Citrobacter spp. and E. cloacae with 7%. CONCLUSION: Clinical pathogens vary by incidence density with temperature. Significant higher incidence densities of Gram-negative pathogens were observed during summer whereas S. pneumoniae peaked in winter. There is increasing evidence that different seasonality due to physiologic changes underlies

  12. Lumbar Spinal Stenosis Has a Negative Impact on Quality of Life Compared with Other Comorbidities: An Epidemiological Cross-Sectional Study of 1862 Community-Dwelling Individuals

    Directory of Open Access Journals (Sweden)

    Koji Otani

    2013-01-01

    Full Text Available Lumbar spinal stenosis (LSS is common in the elderly. However, there have been few reports on its impact on quality of life (QoL in community-dwelling individuals. The purpose of this study was to clarify how symptomatic LSS affects QoL at the community level. A total of 1862 people (697 males and 1165 females, most subjects were between 40 and 85 y.o. agreed to participate and were interviewed. The presence of symptomatic LSS was assessed by a specially designed questionnaire. The Medical Outcomes Study 36-Item Short Form Health Survey (SF-36 was also administered. In addition, the presence of comorbid conditions that affect QoL, such as osteoarthritis of the knee and hip, cardiovascular disease, cerebrovascular disease, or respiratory disease, was also analyzed. The prevalence of symptomatic LSS gradually increased with age. Furthermore, the presence of symptomatic LSS had a strong negative effect on all 8 physical and mental domains and the physical component summary (PCS (OR: 1.547–2.544 but not the mental component summary (MCS. In comparison with comorbid conditions, LSS had a much stronger negative impact on health-related QoL (HR-QoL. The current study confirmed that the presence of symptomatic LSS might have a strong negative influence on HR-QoL in the community setting.

  13. Negative impacts of a vertebrate predator on insect pollinator visitation and seed output in Chuquiraga oppositifolia, a high Andean shrub.

    Science.gov (United States)

    Muñoz, Alejandro A; Arroyo, Mary T K

    2004-01-01

    Studies on plant-pollinator interactions have largely neglected the potential negative effects of the predators of pollinators on seed output, even though anti-predatory behaviour of pollinators may affect visitation patterns, pollen transfer, and therefore potentially, plant reproductive output. We tested the hypothesis that the presence of lizards and insectivorous birds, by reducing pollinator visitation, can have significant negative effects on seed output in the insect-pollinated, genetically self-incompatible lower alpine Andean shrub, Chuquiraga oppositifolia (Asteraceae). The lower alpine belt supports a high density of territorial Liolaemus (Tropiduridae) lizards and low shrubs interspersed among rocks of varying sizes, the latter inhabited by lizards and commonly used by flycatchers Muscisaxicola (Tyrannidae) as perching sites. In a 2x2 factorial predator-exclusion experiment, visitation rates of the most frequent pollinators of C. oppositifolia (the satyrid butterfly Cosmosatyrus chilensis and the syrphid fly Scaeva melanostoma), the duration of pollinator visits, and seed output, were 2-4 times greater when lizards were excluded, while birds had no effect. In a natural experiment, visits by S. melanostoma were 9 times shorter, and pollinator visitation rates of C. chilensis and S. melanostoma, and C. oppositifolia seed output were 2-3 times lower on shrubs growing adjacent to lizard-occupied rocks compared to those growing distant from rocks. Our results, verified for additional Andean sites, suggest that lizard predators can alter the behaviour of pollinators and elicit strong top-down indirect negative effects on seed output. Such effects may be especially important in high alpine plant communities, where pollinator activity can be low and erratic, and pollen limitation has been reported. PMID:14551828

  14. Countermeasures to Mitigate the Negative Impact of Sensory Deprivation and Social Isolation in Long-Duration Space Flight

    Science.gov (United States)

    Bachman, Katharine Ridgeway OBrien; Otto, Christian; Leveton, Lauren

    2012-01-01

    Long-duration space flight presents several challenges to the behavioral health of crew members. The environment that they are likely to experience will be isolated, confined, and extreme (ICE) and, as such, crew members will experience extreme sensory deprivation and social isolation. The current paper briefly notes the behavioral, cognitive, and affective consequences of psychological stress induced by ICE environments and proposes nine countermeasures aimed at mitigating the negative effects of sensory deprivation and social isolation. Implementation of countermeasures aims to maintain successful crew performance and psychological well-being in a long-duration space flight mission.

  15. Impact on regional recurrence and survival of axillary surgery in women with node-negative primary breast cancer

    DEFF Research Database (Denmark)

    Axelsson, C K; Düring, M; Christiansen, P M;

    2009-01-01

    -negative primary breast cancer treated solely by surgery. Median follow-up was 9 years. RESULTS: The number of lymph nodes removed correlated with a reduction in the rate of subsequent axillary recurrence (from 2.1 to 0.4 per cent; P = 0.037), local recurrence (from 7.4 to 3.8 per cent; P < 0.001) distant......BACKGROUND: This study examined whether axillary lymph node dissection (ALND) with removal of many normal lymph nodes resulted in a reduced rate of axillary recurrence and better survival, as reported in recent studies. METHODS: The follow-up analyses were based on 8657 patients with node...

  16. Clinical Impact of Laboratory Implementation of Verigene BC-GN Microarray-Based Assay for Detection of Gram-Negative Bacteria in Positive Blood Cultures.

    Science.gov (United States)

    Walker, Tamar; Dumadag, Sandrea; Lee, Christine Jiyoun; Lee, Seung Heon; Bender, Jeffrey M; Cupo Abbott, Jennifer; She, Rosemary C

    2016-07-01

    Gram-negative bacteremia is highly fatal, and hospitalizations due to sepsis have been increasing worldwide. Molecular tests that supplement Gram stain results from positive blood cultures provide specific organism information to potentially guide therapy, but more clinical data on their real-world impact are still needed. We retrospectively reviewed cases of Gram-negative bacteremia in hospitalized patients over a 6-month period before (n = 98) and over a 6-month period after (n = 97) the implementation of a microarray-based early identification and resistance marker detection system (Verigene BC-GN; Nanosphere) while antimicrobial stewardship practices remained constant. Patient demographics, time to organism identification, time to effective antimicrobial therapy, and other key clinical parameters were compared. The two groups did not differ statistically with regard to comorbid conditions, sources of bacteremia, or numbers of intensive care unit (ICU) admissions, active use of immunosuppressive therapy, neutropenia, or bacteremia due to multidrug-resistant organisms. The BC-GN panel yielded an identification in 87% of Gram-negative cultures and was accurate in 95/97 (98%) of the cases compared to results using conventional culture. Organism identifications were achieved more quickly post-microarray implementation (mean, 10.9 h versus 37.9 h; P < 0.001). Length of ICU stay, 30-day mortality, and mortality associated with multidrug-resistant organisms were significantly lower in the postintervention group (P < 0.05). More rapid implementation of effective therapy was statistically significant for postintervention cases of extended-spectrum beta-lactamase-producing organisms (P = 0.049) but not overall (P = 0.12). The Verigene BC-GN assay is a valuable addition for the early identification of Gram-negative organisms that cause bloodstream infections and can significantly impact patient care, particularly when resistance markers are detected. PMID:27098961

  17. Negative Attitudes, Network and Education

    DEFF Research Database (Denmark)

    Bennett, Patrick; la Cour, Lisbeth; Larsen, Birthe;

    that more negative attitudes against immigrants has a positive impact on education in one case and a negative impact in the other and has no impact on natives. Immigration improves employment perspectives for immigrants and thereby increases immigrant education whereas endogenous negative attitudes......We consider the impact of negative attitudes against immigrants and immigration on educational choice in a search and wage bargaining model including networking. We consider two cases in terms of the importance of negative attitudes againts immigrants for high and low educated individuals and find...

  18. Prolonged length of stay associated with air leak following pulmonary resection has a negative impact on hospital margin

    OpenAIRE

    Wood,, J.S.; Lauer LM; Layton A; Tong KB

    2016-01-01

    Douglas E Wood,1 Lisa M Lauer,2 Andrew Layton,3 Kuo B Tong3 1Division of Cardiothoracic Surgery, Department of Surgery, University of Washington, Seattle, 2Spiration Inc., Redmond, WA, 3Quorum Consulting, Inc., San Francisco, CA, USABackground: Protracted hospitalizations due to air leaks following lung resections are a significant source of morbidity and prolonged hospital length of stay (LOS), with potentially significant impact on hospital margins. This study aimed to evaluate the relation...

  19. Smoking has a negative impact upon health related quality of life after treatment for head and neck cancer

    DEFF Research Database (Denmark)

    Jensen, Kenneth; Jensen, Anders Bonde; Grau, Cai

    2006-01-01

    To examine the influence of smoking on observer based morbidity scores and patient assessed health related quality of life after treatment for head and neck cancer. The results of EORTC C30 and H&N35 questionnaires and DAHANCA morbidity scores were studied according to smoking status in 114...... recurrence free head and neck cancer patients. In contrast to observer based toxicity scoring, smoking had a significantly negative influence on 20 of the 33 quality of life scales. Previous smokers had quality of life scores in between never smokers and continuous smokers. Smoking after treatment of head...... and neck cancer adversely influenced a wide range of quality of life endpoints. Quitters had better quality of life than patients who continued to smoke after treatment, suggesting that smoking cessation may improve quality of life in addition to reducing the risk of new cancer. Udgivelsesdato: 2007...

  20. Positive or negative? The impact of X-ray feedback on the formation of direct collapse black hole seeds

    Science.gov (United States)

    Regan, John A.; Johansson, Peter H.; Wise, John H.

    2016-09-01

    A nearby source of Lyman-Werner (LW) photons is thought to be a central component in dissociating H2 and allowing for the formation of a direct collapse black hole seed. Nearby sources are also expected to produce copious amounts of hydrogen ionizing photons and X-ray photons. We study here the feedback effects of the X-ray photons by including a spectrum due to high-mass X-ray binaries on top of a galaxy with a stellar spectrum. We explicitly trace photon packages emerging from the nearby source and track the radiative and chemical effects of the multifrequency source (Ephoton = 0.76 eV → 7500 eV). We find that X-rays have a strongly negative feedback effect, compared to a stellar only source, when the radiative source is placed at a separation greater than ≳ 1 kpc. The X-rays heat the low and medium density gas in the envelope surrounding the collapsing halo suppressing the mass inflow. The result is a smaller enclosed mass compared to the stellar only case. However, for separations of ≲ 1 kpc, the feedback effects of the X-rays becomes somewhat neutral. The enhanced LW intensity at close separations dissociates more H2 and this gas is heated due to stellar photons alone, the addition of X-rays is then not significant. This distance dependence of X-ray feedback suggests that a Goldilocks zone exists close to a forming galaxy where X-ray photons have a much smaller negative feedback effect and ideal conditions exist for creating massive black hole seeds.

  1. Does Off-Pump Coronary Artery Bypass Grafting Negatively Impact Long-Term Survival and Freedom from Reintervention?

    Science.gov (United States)

    Raja, Shahzad G.; Husain, Mubassher; Popescu, Florentina L.; Chudasama, Dimple; Daley, Siobhan; Amrani, Mohamed

    2013-01-01

    Recently published evidence has raised concerns about worse late mortality and increasing need for reintervention after off-pump coronary artery bypass grafting. We undertook this study to assess the impact of off-pump coronary artery bypass grafting on survival and freedom from reintervention at 10 years. From January 2002 to December 2002, 307 consecutive patients who had isolated multivessel off-pump coronary artery bypass grafting at our institution were compared to a control group of 397 patients that underwent multivessel on-pump coronary artery bypass grafting during the same period. In addition, univariate and risk-adjusted comparisons between the two groups were performed at 10 years. Kaplan-Meier survival was similar for the two cohorts. After adjusting for clinical covariates, off-pump coronary artery bypass grafting did not emerge as a significant independent predictor of long-term mortality (Hazard Ratio 0.91; 95% Confidence Interval 0.70–1.12), readmission to hospital for cardiac cause (Hazard Ratio 0.96; 95% Confidence Interval 0.78–1.10), or the need for reintervention (Hazard Ratio 0.93; 95% Confidence Interval 0.87–1.05). Off-pump coronary artery bypass grafting compared with on-pump coronary artery bypass grafting does not adversely impact survival or freedom from reintervention at a 10-year follow-up. PMID:24106710

  2. Does Off-Pump Coronary Artery Bypass Grafting Negatively Impact Long-Term Survival and Freedom from Reintervention?

    Directory of Open Access Journals (Sweden)

    Shahzad G. Raja

    2013-01-01

    Full Text Available Recently published evidence has raised concerns about worse late mortality and increasing need for reintervention after off-pump coronary artery bypass grafting. We undertook this study to assess the impact of off-pump coronary artery bypass grafting on survival and freedom from reintervention at 10 years. From January 2002 to December 2002, 307 consecutive patients who had isolated multivessel off-pump coronary artery bypass grafting at our institution were compared to a control group of 397 patients that underwent multivessel on-pump coronary artery bypass grafting during the same period. In addition, univariate and risk-adjusted comparisons between the two groups were performed at 10 years. Kaplan-Meier survival was similar for the two cohorts. After adjusting for clinical covariates, off-pump coronary artery bypass grafting did not emerge as a significant independent predictor of long-term mortality (Hazard Ratio 0.91; 95% Confidence Interval 0.70–1.12, readmission to hospital for cardiac cause (Hazard Ratio 0.96; 95% Confidence Interval 0.78–1.10, or the need for reintervention (Hazard Ratio 0.93; 95% Confidence Interval 0.87–1.05. Off-pump coronary artery bypass grafting compared with on-pump coronary artery bypass grafting does not adversely impact survival or freedom from reintervention at a 10-year follow-up.

  3. Perceived discrimination amongst young people in socio-economically disadvantaged communities: Parental support and community identity buffer (some) negative impacts of stigma.

    Science.gov (United States)

    Bradshaw, Daragh; Jay, Sarah; McNamara, Namh; Stevenson, Clifford; Muldoon, Orla T

    2016-06-01

    There is increasing acceptance that children are not unaware of when they are targets of discrimination. However, discrimination as a consequence of socio-economic disadvantage remains understudied. The aim of this study was to examine the impact of perceived discrimination on well-being, perceptions of safety and school integration amongst children growing up within socio-economically disadvantaged communities in Limerick, Ireland. Mediation analysis was used to explore these relationships and to examine the potential role of parental support and community identity in boys and girls in the 6th to 9th year of compulsory education (N = 199). Results indicate perceived discrimination contributed to negative outcomes in terms of school integration, perceptions of safety and levels of well-being. Age and gender differences were observed which disadvantaged boys and younger children. All negative outcomes were buffered by parental support. Community identity also protected young people in terms of feelings of school integration and risk but not in terms of psychological well-being. Findings are discussed in terms of the different role of family and community supports for children negotiating negative social representations of their community. PMID:26490256

  4. The meaning of collective terrorist threat: understanding the subjective causes of terrorism reduces its negative psychological impact.

    Science.gov (United States)

    Fischer, Peter; Postmes, Tom; Koeppl, Julia; Conway, Lianne; Fredriksson, Tom

    2011-05-01

    This article hypothesized that the possibility to construct intellectual meaning of a terrorist attack (i.e., whether participants can cognitively understand why the perpetrators did their crime) reduces the negative psychological consequences typically associated with increased terrorist threat. Concretely, the authors investigated the effect of intellectual meaning (induced by providing additional information about potential economic, cultural, and historical reasons for the terrorist attack) on perceived terrorist threat and associated emotional well-being. Study 1 revealed that pictures of terrorist attacks elicited less experienced terrorist threat when they were presented with background information about the terrorists' motives (meaning provided) rather than without additional background information (no meaning provided). Study 2 replicated this effect with a different manipulation of terrorist threat (i.e., newspaper article) and clarified the underlying psychological process: Participants in the high terror salience condition with meaning provided experienced less terrorist threat and thus more emotional well-being in the face of crisis than participants in the high terror salience condition without meaning provided. Theoretical and practical implications in the context of psychological health and mass media effects are discussed. PMID:20587476

  5. Auditory Scene Analysis and sonified visual images. Does consonance negatively impact on object formation when using complex sonified stimuli?

    Directory of Open Access Journals (Sweden)

    David J Brown

    2015-10-01

    Full Text Available A critical task for the brain is the sensory representation and identification of perceptual objects in the world. When the visual sense is impaired, hearing and touch must take primary roles and in recent times compensatory techniques have been developed that employ the tactile or auditory system as a substitute for the visual system. Visual-to-auditory sonifications provide a complex, feature-based auditory representation that must be decoded and integrated into an object-based representation by the listener. However, we don’t yet know what role the auditory system plays in the object integration stage and whether the principles of auditory scene analysis apply. Here we used coarse sonified images in a two-tone discrimination task to test whether auditory feature-based representations of visual objects would be confounded when their features conflicted with the principles of auditory consonance. We found that listeners (N = 36 performed worse in an object recognition task when the auditory feature-based representation was harmonically consonant. We also found that this conflict was not negated with the provision of congruent audio-visual information. The findings suggest that early auditory processes of harmonic grouping dominate the object formation process and that the complexity of the signal, and additional sensory information have limited effect on this.

  6. Positive or Negative? The Impact of X-ray Feedback on the Formation of Direct Collapse Black Hole Seeds

    CERN Document Server

    Regan, John A; Wise, John H

    2016-01-01

    A nearby source of Lyman-Werner (LW) photons is thought to be a central component in dissociating H$_2$ and allowing for the formation of a direct collapse black hole seed. Nearby sources are also expected to produce copious amounts of hydrogen ionising photons and X-ray photons. We study here the feedback effects of the X-ray photons by including a spectrum due to high-mass X-ray binaries on top of a galaxy with a stellar spectrum. We explicitly trace photon packages emerging from the nearby source and track the radiative and chemical effects of the multi-frequency source $(E_{\\rm photon} = \\rm{0.76\\ eV \\rightarrow 7500\\ eV}$). We find that X-rays have a strongly negative feedback effect, compared to a stellar only source, when the radiative source is placed at a separation greater than $\\gtrsim 1 \\ \\rm kpc$. The X-rays heat the low and medium density gas in the envelope surrounding the collapsing halo suppressing the mass inflow. The result is a smaller enclosed mass compared to the stellar only case. Howev...

  7. Negative impacts of high temperatures on growth of black spruce forests intensify with the anticipated climate warming

    Science.gov (United States)

    Girardin, M. P.; Hogg, T.; Kurz, W.; Bernier, P. Y.; Guo, X. J.; Cyr, G.

    2015-12-01

    An increasing number of studies conclude that water limitations and heat stress may hinder the capacity of black spruce (Picea mariana (Mill.) B.S.P.) trees, a dominant species of Canada's boreal forests, to grow and assimilate atmospheric carbon. However, there is currently no scientific consensus on the future of these forests over the next century in the context of widespread climate warming. The large spatial extent of black spruce forests across the Canadian boreal forest and associated variability in climate, demography and site conditions pose challenges for projecting future climate change responses. Here we provide an evaluation of the impacts of climate warming and drying, as well as increasing [CO2], on the aboveground productivity of black spruce forests across Canada south of 60ºN for the period 1971 to 2100. We use a new extensive network of tree-ring data obtained from Canada's National Forest Inventory, spatially-explicit simulations of Net Primary Productivity (NPP) and its drivers, and multivariate statistical modelling. We found that soil water availability is a significant driver of black spruce inter-annual variability in productivity across broad areas of the western to eastern Canadian boreal forest. Inter-annual variability in productivity was also found to be driven by autotrophic respiration in the warmest regions. In most regions, the impacts of soil water availability and respiration on inter-annual variability in productivity occurred during the phase of carbohydrate accumulation the year preceding tree ring formation. Results from projections suggest an increase in the importance of soil water availability and respiration as limiting factors on NPP over the next century due to warming, but this response may vary to the extent that other factors such as carbon dioxide fertilization, and respiration acclimation to high temperature, contribute to dampening these limitations.

  8. Negative impacts of high temperatures on growth of black spruce forests intensify with the anticipated climate warming.

    Science.gov (United States)

    Girardin, Martin P; Hogg, Edward H; Bernier, Pierre Y; Kurz, Werner A; Guo, Xiao Jing; Cyr, Guillaume

    2016-02-01

    An increasing number of studies conclude that water limitations and heat stress may hinder the capacity of black spruce (Picea mariana (Mill.) B.S.P.) trees, a dominant species of Canada's boreal forests, to grow and assimilate atmospheric carbon. However, there is currently no scientific consensus on the future of these forests over the next century in the context of widespread climate warming. The large spatial extent of black spruce forests across the Canadian boreal forest and associated variability in climate, demography, and site conditions pose challenges for projecting future climate change responses. Here we provide an evaluation of the impacts of climate warming and drying, as well as increasing [CO2 ], on the aboveground productivity of black spruce forests across Canada south of 60°N for the period 1971 to 2100. We use a new extensive network of tree-ring data obtained from Canada's National Forest Inventory, spatially explicit simulations of net primary productivity (NPP) and its drivers, and multivariate statistical modeling. We found that soil water availability is a significant driver of black spruce interannual variability in productivity across broad areas of the western to eastern Canadian boreal forest. Interannual variability in productivity was also found to be driven by autotrophic respiration in the warmest regions. In most regions, the impacts of soil water availability and respiration on interannual variability in productivity occurred during the phase of carbohydrate accumulation the year preceding tree-ring formation. Results from projections suggest an increase in the importance of soil water availability and respiration as limiting factors on NPP over the next century due to warming, but this response may vary to the extent that other factors such as carbon dioxide fertilization, and respiration acclimation to high temperature, contribute to dampening these limitations. PMID:26507106

  9. The impact of early parenting bonding on young adults' internet addiction, through the mediation effects of negative relating to others and sadness.

    Science.gov (United States)

    Kalaitzaki, Argyroula E; Birtchnell, John

    2014-03-01

    The aim of the present study is the investigation of the potential role of negative relating to others, perceived loneliness, sadness, and anxiety, as mediators of the association between early parental bonding and adult Internet Addiction (IA). The factorial structure of the Internet Addiction Test (IAT) and the prevalence rates of it in a Greek sample will also be investigated. A total of 774 participants were recruited from a Technological Education Institute (mean age=20.2, SD=2.8) and from high school technical schools (mean age=19.9, SD=7.4). The IAT was used to measure the degree of problematic Internet use behaviors; the Parental Bonding Instrument was used to assess one's recalled parenting experiences during the first 16years of life; the shortened Person's Relating to Others Questionnaire was used to assess one's negative (i.e. maladaptive) relating to others (NRO). Both exploratory and confirmatory factor analyses confirmed the three-factor structure of the IAT. Only 1.0% of the sample was severely addicted to the Internet. The mediated effects of only the NRO and sadness were confirmed. Negative relating to others was found to fully mediate the effect of both the father's optimal parenting and affectionless control on IA, whereas sadness was found to fully mediate the effect of the mother's optimal parenting on IA. Overall, the results suggest that parenting style has an indirect impact on IA, through the mediating role of negative relating to others or sadness in later life. Both family-based and individual-based prevention and intervention efforts may reduce the incidence of IA. PMID:24368006

  10. Rapid warming and drought negatively impact population size and reproductive dynamics of an avian predator in the arid southwest.

    Science.gov (United States)

    Cruz-McDonnell, Kirsten K; Wolf, Blair O

    2016-01-01

    Avian communities of arid ecosystems may be particularly vulnerable to global climate change due to the magnitude of projected change for desert regions and the inherent challenges for species residing in resource limited ecosystems. How arid-zone birds will be affected by rapid increases in air temperature and increased drought frequency and severity is poorly understood because avian responses to climate change have primarily been studied in the relatively mesic northern temperate regions. We studied the effects of increasing air temperature and aridity on a Burrowing Owl (Athene cunicularia) population in the southwestern United States from 1998 to 2013. Over 16 years, the breeding population declined 98.1%, from 52 pairs to 1 pair, and nest success and fledgling output also declined significantly. These trends were strongly associated with the combined effects of decreased precipitation and increased air temperature. Arrival on the breeding grounds, pair formation, nest initiation, and hatch dates all showed significant delays ranging from 9.4 to 25.1 days over 9 years, which have negative effects on reproduction. Adult and juvenile body mass decreased significantly over time, with a loss of 7.9% mass in adult males and 10.9% mass in adult females over 16 years, and a loss of 20.0% mass in nestlings over 8 years. Taken together, these population and reproductive trends have serious implications for local population persistence. The southwestern United States has been identified as a climate change hotspot, with projections of warmer temperatures, less winter precipitation, and an increase in frequency and severity of extreme events including drought and heat waves. An increasingly warm and dry climate may contribute to this species' decline and may already be a driving force of their apparent decline in the desert southwest. PMID:26367541

  11. Silviculture and economic benefits of producing wood energy from conventional forestry systems and measures to mitigate negative impacts

    International Nuclear Information System (INIS)

    Activity ''Forest Energy Production'' focused on the development and evaluation, in the context of conventional forestry systems, silvicultural and forest management practices which optimise productivity for traditional products and wood for energy, while safeguarding the forest ecosystem. A series of meetings, workshops, and review papers involving the three participating countries of Canada, Sweden, and the United Kingdom were planned and completed. An additional workshop in Switzerland was also held. Increasing production of biomass for energy is generally found to be positive, from silvicultural, economic, and environmental perspectives. Eight specific forest management systems were investigated and/or reported: five conventional systems involving multiple products in softwood and mixed wood, and three hardwood systems emphasising production of biomass for energy. Modifications in silvercultural practice to also produce biomass for energy included increased opportunities for thinnings, intermediate cuttings, and stand and site rehabilitation as well as more flexible and efficient harvesting systems. Economic benefits accrued from increased investment in harvesting and burning technology, improvements in stand quality and site utilisation, and substitution for more expensive fuels, especially if all costs are considered. Environmental effects were found to be generally positive, but negative effects of nutrient and organic matter removal on the overall sustainability of specific systems are possible. These need to be addressed. Harvest and management guidelines are being designed and put into practice. Social, institutional, and technical barriers to the increased use of biomass for energy are being addressed by specific strategies and initiatives involving programs and incentives for production, market development, research and education. Net positive effects indicate increased use of forest biomass for energy, in the short and long term. (Abstract Truncated)

  12. Flow cytometric evaluation of physico-chemical impact on Gram-positive and Gram-negative bacteria

    Directory of Open Access Journals (Sweden)

    Antje eFröhling

    2015-09-01

    Full Text Available Since heat sensitivity of fruits and vegetables limits the application of thermal inactivation processes, new emerging inactivation technologies have to be established to fulfil the requirements of food safety without affecting the produce quality. The efficiency of inactivation treatments has to be ensured and monitored. Monitoring of inactivation effects is commonly performed using traditional cultivation methods which have the disadvantage of the time span needed to obtain results.The aim of this study was to compare the inactivation effects of peracetic acid (PAA, ozonated water (O3 and cold atmospheric pressure plasma (CAPP on Gram-positive and Gram-negative bacteria using flow cytometric methods. E. coli cells were completely depolarized after treatment (15 s with 0.25 % PAA at 10 °C, and after treatment (10 s with 3.8 mg l-1 O3 at 12°C. The membrane potential of CAPP treated cells remained almost constant at an operating power of 20 W over a time period of 3 min, and subsequently decreased within 30 s of further treatment. Complete membrane permeabilization was observed after 10 s O3 treatment, but treatment with PAA and CAPP did not completely permeabilize the cells within 2 min and 4 min, respectively. Similar results were obtained for esterase activity. O3 inactivates cellular esterase but esterase activity was detected after 4 min CAPP treatment and 2 min PAA treatment. L. innocua cells and P. carotovorum cells were also permeabilized instantaneously by O3 treatment at concentrations of 3.8 ± 1 mg l-1. However, higher membrane permeabilization of L. innocua and P. carotovorum than of E. coli was observed at CAPP treatment of 20 W. The degree of bacterial damage due to the inactivation processes is highly dependent on treatment parameters as well as on treated bacteria. Important information regarding the inactivation mechanisms can be obtained by flow cytometric measurements and this enables the definition of critical process

  13. Negative Happiness

    OpenAIRE

    Adam Barkman

    2009-01-01

    In this paper, I will compare the philosophies of the Buddha and Epicurus. Unusual? Yes. But my intention herein is not a general comparison; rather, I want to explore to what extent these two men accepted what I call “negative happiness.” What is negative, and by extension, positive, happiness? I think we can prepare ourselves for this distinction with two analogous distinctions: (1) the distinction between positive and negative freedom, wherein positive freedom sees true freedom as interna...

  14. Coaching to vision versus coaching to improvement needs: a preliminary investigation on the differential impacts of fostering positive and negative emotion during real time executive coaching sessions.

    Science.gov (United States)

    Howard, Anita R

    2015-01-01

    Drawing on intentional change theory (ICT; Boyatzis, 2006), this study examined the differential impact of inducing coaching recipients' vision/positive emotion versus improvement needs/negative emotion during real time executive coaching sessions. A core aim of the study was to empirically test two central ICT propositions on the effects of using the coached person's Positive Emotional Attractor (vision/PEA) versus Negative Emotional Attractor (improvement needs/NEA) as the anchoring framework of a onetime, one-on-one coaching session on appraisal of 360° feedback and discussion of possible change goals. Eighteen coaching recipients were randomly assigned to two coaching conditions, the coaching to vision/PEA condition and the coaching to improvement needs/NEA condition. Two main hypotheses were tested. Hypothesis1 predicted that participants in the vision/PEA condition would show higher levels of expressed positive emotion during appraisal of 360° feedback results and discussion of change goals than recipients in the improvement needs/NEA condition. Hypothesis2 predicted that vision/PEA participants would show lower levels of stress immediately after the coaching session than improvement needs/NEA participants. Findings showed that coaching to vision/the PEA fostered significantly lower levels of expressed negative emotion and anger during appraisal of 360° feedback results as compared to coaching to improvements needs/the NEA. Vision-focused coaching also fostered significantly greater exploration of personal passions and future desires, and more positive engagement during 360° feedback appraisal. No significant differences between the two conditions were found in emotional processing during discussion of change goals or levels of stress immediately after the coaching session. Current findings suggest that vision/PEA arousal versus improvement needs/NEA arousal impact the coaching process in quite different ways; that the coach's initial framing of the

  15. Elevated temperatures and long drought periods have a negative impact on survival and fitness of strongylid third stage larvae.

    Science.gov (United States)

    Knapp-Lawitzke, Friederike; von Samson-Himmelstjerna, Georg; Demeler, Janina

    2016-04-01

    In grazing cattle, infections with gastrointestinal nematodes pose some of the most important health threats and subclinical infections result in considerable production losses. While there is little doubt that climate change will affect grazing ruminants directly, mean temperature increases of ∼3°C and longer drought stress periods in summer may also influence the free-living stages of parasitic nematodes. Hostile climatic conditions reduce the number of L3s on pasture and therefore the refugium, which is expected to result in a higher selection pressure, accelerating development of resistance against anthelmintic drugs. The aim of the current experiments was to investigate the effects of drought stress and different temperature/humidity ranges over time on the survival and fitness of Cooperia oncophora L3s and their distribution in grass and soil under controlled conditions using a climate chamber. Grass containers inoculated with L3s were analysed after 1-6weeks using descriptive statistics as well as linear models. A large proportion of L3s was recovered from soil where fitness was also better preserved than on grass. Numbers and fitness of recovered L3s declined with duration in the climate chamber under both temperature profiles. However, the results of the linear models confirmed that higher temperatures (20-33°C versus 17-22.6°C) significantly impaired survival, distribution and fitness of L3s. Application of drought stress, known as another important factor, had a surprisingly smaller impact than its duration or higher temperatures. The climate chamber enabled exclusion of confounding factors and therefore accurate interpretation of the investigated climatic aspects. The obtained results highlight the relative importance of those factors, and will help to design better models for the population dynamics of L3s on pasture in the future. Additionally, the outcomes of these investigations may offer explanations regarding interdependencies of development

  16. Fertilization of sea urchin eggs and sperm motility are negatively impacted under low hypergravitational forces significant to space flight

    Science.gov (United States)

    Tash, J. S.; Kim, S.; Schuber, M.; Seibt, D.; Kinsey, W. H.

    2001-01-01

    Sperm and other flagellates swim faster in microgravity (microG) than in 1 G, raising the question of whether fertilization is altered under conditions of space travel. Such alterations have implications for reproduction of plant and animal food and for long-term space habitation by man. We previously demonstrated that microG accelerates protein phosphorylation during initiation of sperm motility but delays the sperm response to the egg chemotactic factor, speract. Thus sperm are sensitive to changes in gravitational force. New experiments using the NiZeMi centrifugal microscope examined whether low hypergravity (hyperG) causes effects opposite to microG on sperm motility, signal transduction, and fertilization. Sperm % motility and straight-line velocity were significantly inhibited by as little as 1.3 G. The phosphorylation states of FP130, an axonemal phosphoprotein, and FP160, a cAMP-dependent salt-extractable flagellar protein, both coupled to motility activation, showed a more rapid decline in hyperG. Most critically, hyperG caused an approximately 50% reduction in both the rate of sperm-egg binding and fertilization. The similar extent of inhibition of both fertilization parameters in hyperG suggests that the primary effect is on sperm rather than eggs. These results not only support our earlier microG data demonstrating that sperm are sensitive to small changes in gravitational forces but more importantly now show that this sensitivity affects the ability of sperm to fertilize eggs. Thus, more detailed studies on the impact of space flight on development should include studies of sperm function and fertilization.

  17. Simulated leakage of high pCO2 water negatively impacts bivalve dominated infaunal communities from the Western Baltic Sea.

    Science.gov (United States)

    Schade, Hanna; Mevenkamp, Lisa; Guilini, Katja; Meyer, Stefanie; Gorb, Stanislav N; Abele, Doris; Vanreusel, Ann; Melzner, Frank

    2016-01-01

    Carbon capture and storage is promoted as a mitigation method counteracting the increase of atmospheric CO2 levels. However, at this stage, environmental consequences of potential CO2 leakage from sub-seabed storage sites are still largely unknown. In a 3-month-long mesocosm experiment, this study assessed the impact of elevated pCO2 levels (1,500 to 24,400 μatm) on Cerastoderma edule dominated benthic communities from the Baltic Sea. Mortality of C. edule was significantly increased in the highest treatment (24,400 μatm) and exceeded 50%. Furthermore, mortality of small size classes (0-1 cm) was significantly increased in treatment levels ≥6,600 μatm. First signs of external shell dissolution became visible at ≥1,500 μatm, holes were observed at >6,600 μatm. C. edule body condition decreased significantly at all treatment levels (1,500-24,400 μatm). Dominant meiofauna taxa remained unaffected in abundance. Densities of calcifying meiofauna taxa (i.e. Gastropoda and Ostracoda) decreased in high CO2 treatments (>6,600 μatm), while the non - calcifying Gastrotricha significantly increased in abundance at 24,400 μatm. In addition, microbial community composition was altered at the highest pCO2 level. We conclude that strong CO2 leakage can alter benthic infauna community composition at multiple trophic levels, likely due to high mortality of the dominant macrofauna species C. edule. PMID:27538361

  18. Phytochrome Signaling in Green Arabidopsis Seedlings: Impact Assessment of a Mutually Negative phyB-PIF Feedback Loop

    Institute of Scientific and Technical Information of China (English)

    Pablo Leivar; Elena Monte; Megan M. Cohn; Peter H. Quail

    2012-01-01

    The reversibly red (R)/far-red (FR)-Iight-responsive phytoch rome (phy) photosensory system initiates both the deetiolation process in dark-germinated seedlings upon first exposure to light,and the shade-avoidance process in fully deetiolated seedlings upon exposure to vegetational shade.The intracellular signaling pathway from the light-activated photoreceptor conformer (Pfr) to the transcriptional network that drives these responses involves direct,physical interaction of Pfr with a small subfamily of bHLH transcription factors,termed Phy-lnteracting Factors (PIFs),which induces rapid PIF proteolytic degradation.In addition,there is evidence of further complexity in light-grown seedlings,whereby phyB-PIF interaction reciprocally induces phyB degradation,in a mutually-negative,feedback-loop configuration.Here,to assess the relative contributions of these antagonistic activities to the net phenotypic readout in light-grown seedlings,we have examined the magnitude of the light- and simulated-shade-induced responses of a pentuple phyBpif1pif3pif4pif5 (phyBpifq) mutant and various multiple pif-mutant combinations.The data (1) reaffirm that phyB is the predominant,if not exclusive,photoreceptor imposing the inhibition of hypocotyl elongation in deetiolating seedlings in response to prolonged continuous R irradiation and (2) show that the PIF quartet (PIF1,PIF3,PIF4,and PIF5) retain and exert a dual capacity to modulate hypocotyl elongation under these conditions,by concomitantly promoting cell elongation through intrinsic transcriptional-regulatory activity,and reducing phyB-inhibitory capacity through feedback-loop-induced phyB degradation.In shade-exposed seedlings,immunoblot analysis shows that the shade-imposed reduction in Pfr levels induces increases in the abundance of PIF3,and mutant analysis indicates that PIF3 acts,in conjunction with PIF4 and PIF5,to promote the known shade-induced acceleration of hypocotyl elongation.Conversely,although the quadruple pifq

  19. Prolonged length of stay associated with air leak following pulmonary resection has a negative impact on hospital margin

    Directory of Open Access Journals (Sweden)

    Wood DE

    2016-05-01

    Full Text Available Douglas E Wood,1 Lisa M Lauer,2 Andrew Layton,3 Kuo B Tong3 1Division of Cardiothoracic Surgery, Department of Surgery, University of Washington, Seattle, 2Spiration Inc., Redmond, WA, 3Quorum Consulting, Inc., San Francisco, CA, USABackground: Protracted hospitalizations due to air leaks following lung resections are a significant source of morbidity and prolonged hospital length of stay (LOS, with potentially significant impact on hospital margins. This study aimed to evaluate the relationship between air leaks, LOS, and financial outcomes among discharges following lung resections.Materials and methods: The Medicare Provider Analysis and Review file for fiscal year 2012 was utilized to identify inpatient hospital discharges that recorded International Classification of Diseases (ICD-9 procedure codes for lobectomy, segmentectomy, and lung volume reduction surgery (n=21,717. Discharges coded with postoperative air leaks (ICD-9-CM codes 512.2 and 512.84 were defined as the air leak diagnosis group (n=2,947, then subcategorized by LOS: 1 <7 days; 2 7–10 days; and 3 ≥11 days. Median hospital charges, costs, payments, and payment-to-cost ratios were compared between non-air leak and air leak groups, and across LOS subcategories.Results: For identified patients, hospital charges, costs, and payments were significantly greater among patients with air leak diagnoses compared to patients without (P<0.001. Hospital charges and costs increased substantially with prolonged LOS, but were not matched by a proportionate increase in hospital payments. Patients with LOS <7, 7–10, and ≥11 days had median hospital charges of US $57,129, $73,572, and $115,623, and costs of $17,594, $21,711, and $33,786, respectively. Hospital payment increases were substantially lower at $16,494, $16,307, and $19,337, respectively. The payment-to-cost ratio significantly lowered with each LOS increase (P<0.001. Higher inpatient hospital mortality was observed among the

  20. In-role perceptions buffer the negative impact of low LMX on helping and enhance the positive impact of high LMX on voice.

    Science.gov (United States)

    Van Dyne, Linn; Kamdar, Dishan; Joireman, Jeffrey

    2008-11-01

    In 2 field studies, we demonstrated that the relationship between leader-member exchange (LMX) and organizational citizenship behavior (OCB) is moderated by employee role perceptions--the extent to which employees view specific types of OCB as in-role behavior (IRB) versus extra-role behavior (ERB). In addition, we predicted and demonstrated that the form of these interactions differs on the basis of the type of OCB. For helping (aimed at the supervisor or the organization), results show a substitute effect in which viewing helping as IRB buffers the negative effect of low-quality LMX on helping. In contrast, for voice (aimed at the supervisor or the organization), results demonstrate an enhancer effect in which viewing voice as IRB amplifies the positive effect of high-quality LMX on voice. We discuss theoretical and practical implications with an emphasis on how conceptual differences in types of OCB influence the interactive effects of role perceptions on LMX-OCB relationships. PMID:19025242

  1. Fractal negations

    OpenAIRE

    Mayor Forteza, Gaspar; Calvo Sánchez, Tomasa

    1994-01-01

    From the concept of attractor of a family of contractive affine transformations in the Euclidean plane R², we study the fractality property of the De Rham function and other singular functions wich derive from it. In particular, we show as fractals the strong negations called k-negations.

  2. Does High-Quality Financial Reporting Mitigate the Negative Impact of Global Financial Crises on Firm Performance? Evidence from the United Kingdom

    Directory of Open Access Journals (Sweden)

    Zhiwei Lin

    2014-12-01

    Full Text Available Prior literature has claimed that accounting plays a negative role in a financial crisis. The current study sought to determine whether this effect is dependent on the quality of financial reporting. Specifically, this study examined the impact of the quality of financial reporting (as measured via earnings quality on liquidity (measured by the bid-ask spread in the equity market during the 2008–2009 global financial crisis in the United Kingdom. We found, as expected, that market liquidity was much lower during the crisis than prior to the crisis; however, firms with high-quality financial reporting suffered fewer negative effects as a result of the financial crisis. The results were robust after controlling for other influences, such as return volatility, loss making, market value of equity, and other potential endogeneity problems. In addition, adopting alternative models for earnings quality did not alter our inferences. Our results support the notion that high-quality accounting information can reduce information asymmetry and hence enhance investor confidence during a financial crisis. The results suggest that a stable financial reporting system is an important part of that overall economic fabric. Our findings will help build a framework on which an overall financial crisis risk-management strategy can be developed to avoid future crises.

  3. Negative Happiness

    Directory of Open Access Journals (Sweden)

    Adam Barkman

    2009-06-01

    Full Text Available In this paper, I will compare the philosophies of the Buddha and Epicurus. Unusual? Yes. But my intention herein is not a general comparison; rather, I want to explore to what extent these two men accepted what I call “negative happiness.” What is negative, and by extension, positive, happiness? I think we can prepare ourselves for this distinction with two analogous distinctions: (1 the distinction between positive and negative freedom, wherein positive freedom sees true freedom as internal control over oneself, while negative freedom sees true freedom as the lack of external coercion, and (2 the distinction between charity and unselfishness, wherein charity stresses selfdenial,though not as an end in itself, whereas unselfishness emphasizes notprimarily doing good things for others but rather going without them ourselves. Thus, in regard to positive and negative happiness, we can say that while positive happiness sees true happiness as a substantial good that makes virtue a constituent of happiness and regards happiness as something more than the avoidance of suffering, negative happiness sees true happiness as simply the absence of suffering.

  4. 大学生手机上网负面影响的对策%Countermeasures of Negative Impact Caused by College Students' Mobile Internet

    Institute of Scientific and Technical Information of China (English)

    刘素娜

    2015-01-01

    The rapid development of mobile phone networks to the students bring endless fun and convenience, but also for the students themselves and the surrounding students, classroom, ideological and political education has brought many nega-tive effects. College students how to solve the negative impact of the mobile Internet is a system that works. This requires a policy-oriented education administrative departments, also need the correct guidance of the media, but also need to improve and enrich the school rules and regulations of the campus culture, the ultimate end result is a positive effort to have the tea-chers and the students themselves actively cooperate.%迅猛发展的手机网络在给大学生带来无尽乐趣与便利的同时,也对学生自身及周边同学、课堂、高校思想政治教育等带来了诸多负面影响。如何解决大学生手机上网产生的负面影响是一个系统的工程。这需要教育行政部门的政策导向,也需要媒体的正确引导,更需要学校规章制度的完善与校园文化的丰富,最终的落脚点是要有教师的积极努力以及学生自身的积极配合。

  5. 灌注负压与标准负压创面治疗的疗效比较%The impact of negative-pressure wound therapy with instillation compared with standard negative-pressure wound therapy

    Institute of Scientific and Technical Information of China (English)

    范伟锋; 区健毅; 陈衍尧; 李锦塘; 朱秋贤; 叶家键

    2015-01-01

    Objective: To evaluate the impact of negative-pressure wound therapy with instillation (NPWTi) compared with standard NPWT. Methods: A total of 142 patients with wound infection were enrolled between 2010 and 2014. Patients were divided into three groups: NPWT group, NPWTi with 6 min dwell time and 20 min dwell time group. The clinical differences among three groups were compared. Results: One hundred forty-two patients (NPWT, n=74; NPWTi, 6-minute dwell time, n=34; and NPWTi, 20-minute dwell time, n=34) were included in the analysis. Number of operative visits was significantly lower for the 6- minute and 20-minute dwell time groups [(2.4 ± 0.9) and (2.6 ± 0.9), respectively] compared with the no-instillation group (P≤0.05). Hospital stay was significantly shorter for the 20-minute dwell time group (11.4 ± 5.1) days compared with the no-instillation group (14.92 ± 9.23) days (P≤0.05). Time to final surgical procedure was significantly shorter for the 6- minute and 20-minute dwell time groups (7.8 ± 5.2 and 7.5 ± 3.1 days, respectively) compared with the no-instillation group (9.23 ± 5.2) days (P<0.05). Percentage of wounds closed before discharge and culture improvement for gram-positive bacteria was significantly higher for the 6-minute dwell time group compared with the no-instillation group (94% vs. 62%, and 90% vs. 63%, P<0.05, respectively). Conclusion: Negative-pressure wound therapy with instillation (6-minute or 20-minute dwell time) is more beneficial than standard negative-pressure wound therapy for the adjunctive treatment of acutely and chronically infected wounds that require hospital admission.%目的:探讨灌注式负压创面治疗与标准负压创面治疗的疗效比较情况。方法:回顾性分析2010年2月-2014年7月因伤口感染就诊于我院的142例患者。详细记录患者的病史及基线等资料,将患者分为灌注式负压治疗组和标准负压治疗组,其中灌注式负压分为6min 和20min 两组

  6. Alpha-synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo: a study in [A30P]alpha-synuclein transgenic mouse.

    Science.gov (United States)

    Unal-Cevik, Isin; Gursoy-Ozdemir, Yasemin; Yemisci, Muge; Lule, Sevda; Gurer, Gunfer; Can, Alp; Müller, Veronica; Kahle, Philip J; Dalkara, Turgay

    2011-03-01

    Alpha-synuclein oligomerization and aggregation are considered to have a role in the pathogenesis of neurodegenerative diseases. However, despite numerous in vitro studies, the impact of aggregates in the intact brain is unclear. In vitro, oxidative/nitrative stress and acidity induce α-synuclein oligomerization. These conditions favoring α-synuclein fibrillization are present in the ischemic brain, which may serve as an in vivo model to study α-synuclein aggregation. In this study, we show that 30-minute proximal middle cerebral artery (MCA) occlusion and 72 hours reperfusion induce oligomerization of wild-type α-synuclein in the ischemic mouse brain. The nonamyloidogenic isoform β-synuclein did not form oligomers. Alpha-synuclein aggregates were confined to neurons and colocalized with ubiquitin immunoreactivity. We also found that 30 minutes proximal MCA occlusion and 24 hours reperfusion induced larger infarcts in C57BL/6(Thy1)-h[A30P]alphaSYN transgenic mice, which have an increased tendency to form synuclein fibrils. Trangenics also developed more selective neuronal necrosis when subjected to 20 minutes distal MCA occlusion and 72 hours reperfusion. Enhanced 3-nitrotyrosine immunoreactivity in transgenic mice suggests that oxidative/nitrative stress may be one of the mechanisms mediating aggregate toxicity. Thus, the increased vulnerability of transgenic mice to ischemia suggests that α-synuclein aggregates not only form during ischemia but also negatively impact neuronal survival, supporting the idea that α-synuclein misfolding may be neurotoxic. PMID:20877387

  7. Prognostic impact of 18F-FDG PET/CT staging and of pathological response to neoadjuvant chemotherapy in triple-negative breast cancer

    International Nuclear Information System (INIS)

    Mortality is high in patients with locally advanced triple-negative breast cancer (TNBC), especially in those with residual tumour after neoadjuvant chemotherapy (NAC). The aim of this study was to determine if pretreatment 18F-FDG PET/CT staging and pathological findings after NAC could together allow stratification of patients into prognostic groups. Initial staging with 18F-FDG PET/CT was performed prospectively in 85 consecutive patients with stage II/III TNBC. Correlations between PET findings and disease-specific survival (DSS) were examined. In patients without distant metastases on PET staging, the impact of pathological response to NAC on DSS was examined. Patterns of recurrence were also analysed. 18F-DG PET/CT revealed distant metastases in 11 of 85 patients (12.9 %). Among 74 M0 patients, 23 (31.1 %) showed a pathological complete response (pCR) at surgery, while 51 had residual invasive disease (no pCR). DSS differed considerably among the three groups of patients (log-rank P 18F-FDG PET/CT findings at initial staging and pathological response at the end of NAC allow three groups of patients with quite different prognoses to be defined. Extraskeletal recurrences predominated. Specific follow-up strategies in patients with TNBC who do not achieve pCR deserve investigation. (orig.)

  8. Impact of type 2 diabetes mellitus on the prognosis of early stage triple-negative breast cancer in People’s Republic of China

    Science.gov (United States)

    Ma, Fang-Jing; Liu, Zhe-Bin; Qu, Li; Hao, Shuang; Liu, Guang-Yu; Wu, Jiong; Shao, Zhi-Ming

    2014-01-01

    Background Type 2 diabetes mellitus (T2DM) is one of the most common chronic metabolic diseases. Increased cause-specific mortality and decreased disease-free survival (DFS) have been reported among cancer patients with T2DM compared with patients without T2DM, even after adjustments of other comorbidities. However, less is known about the impact of T2DM and other comorbidities on DFS in Chinese patients with early stage triple-negative breast cancer (TNBC). Patients and methods We assessed patients who were newly diagnosed with early stage primary TNBC at the Department of Breast Surgery, Fudan University, from 2003 to 2011. Of the 1,100 TNBC patients, 865 female patients had invasive and early stage TNBC. The association of the variables in the T2DM and non-T2DM groups was compared using the Pearson’s chi-square and independent t-tests. DFS was estimated using the Kaplan–Meier method. The effects of T2DM and other possible risk factors on DFS were assessed by Cox proportional hazards regression using univariate or multivariate analysis. Results A total of 865 early stage primary TNBC cases were studied, including 104 (12.02%) subjects with T2DM. Metastatic or recurrent disease was detected in 24 (23.08%) patients in the T2DM group and 35 (4.60%) patients in the non-T2DM group. Patients with T2DM exhibited a significantly lower DFS than patients without T2DM (log-rank P50 or ≤50), menopausal status (post- or premenopausal), tumor size (>5 cm or ≤5 cm), lymph node involvement (positive or negative), and adjuvant chemotherapy (received or not) using the Kaplan–Meier method (log-rank P<0.05). Conclusion In the People’s Republic of China, T2DM is an independent prognostic risk factor that indicates an increased likelihood of recurrence and metastasis in patients with early stage TNBC. The presence of T2DM should be taken into account when evaluating the risk for an early stage TNBC patient. More effective therapeutic regimens are needed for early stage

  9. Impact of type 2 diabetes mellitus on the prognosis of early stage triple-negative breast cancer in People’s Republic of China

    Directory of Open Access Journals (Sweden)

    Ma FJ

    2014-11-01

    Full Text Available Fang-Jing Ma,1–3,* Zhe-Bin Liu,1,2,* Li Qu,4,* Shuang Hao,1,2 Guang-Yu Liu,1,2 Jiong Wu,1,2 Zhi-Ming Shao1,2 1Department of Breast Surgery, Key Laboratory of Breast Cancer in Shanghai, Fudan University Shanghai Cancer Center, 2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People’s Republic of China; 3Department of Breast Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, Xinjiang, People’s Republic of China; 4Department of General Surgery, Zhejiang Hospital, Hangzhou, People’s Republic of China  *These authors have contributed equally to this workBackground: Type 2 diabetes mellitus (T2DM is one of the most common chronic metabolic diseases. Increased cause-specific mortality and decreased disease-free survival (DFS have been reported among cancer patients with T2DM compared with patients without T2DM, even after adjustments of other comorbidities. However, less is known about the impact of T2DM and other comorbidities on DFS in Chinese patients with early stage triple-negative breast cancer (TNBC.Patients and methods: We assessed patients who were newly diagnosed with early stage primary TNBC at the Department of Breast Surgery, Fudan University, from 2003 to 2011. Of the 1,100 TNBC patients, 865 female patients had invasive and early stage TNBC. The association of the variables in the T2DM and non-T2DM groups was compared using the Pearson's chi-square and independent t-tests. DFS was estimated using the Kaplan–Meier method. The effects of T2DM and other possible risk factors on DFS were assessed by Cox proportional hazards regression using univariate or multivariate analysis.Results: A total of 865 early stage primary TNBC cases were studied, including 104 (12.02% subjects with T2DM. Metastatic or recurrent disease was detected in 24 (23.08% patients in the T2DM group and 35 (4.60% patients in the non-T2DM group. Patients with T2DM exhibited a

  10. CT angiography of pulmonary embolism in patients with underlying respiratory disease: impact of multislice CT on image quality and negative predictive value

    International Nuclear Information System (INIS)

    Our objective was to evaluate the impact of multislice CT (MSCT) on image quality and diagnostic value of spiral CT angiograms. Over an 8-month period (January 2000 to August 2000), 134 consecutive patients, including 55 patients with underlying lung disease, underwent MSCT (group 1). Image quality and diagnostic results of CT angiograms were compared with those obtained in 125 consecutive patients, including 58 patients with underlying lung disease, evaluated with thin-collimation single slice CT (SSCT; group 2) over a similar period of time (January 1999 to August 1999). A 3-month clinical follow-up was systematically obtained in all patients who were not anticoagulated in the two groups. For a significantly longer mean z-axis coverage, the mean duration of data acquisition was significantly shorter with MSCT. The frequency of examinations devoid of motion artifacts was significantly higher in group 1 than in group 2. In the absence of significant difference in the quality of vascular enhancement, mainly coded as good or excellent, the proportion of examinations interpretable down to the subsegmental arteries was higher in group 1 (57.5%) than in group 2 (13%) (p<0.0001). The benefits of MSCT were more marked for patients with underlying respiratory disease and did not lead to a higher detection rate of peripheral pulmonary embolism. The negative predictive values of single-slice and multislice CT were 100 and 99%, respectively. Improvement in image quality on MSCT scans accounts for the improved diagnostic accuracy of CT angiography, in particular for patients with impaired respiratory function. (orig.)

  11. Negative impact of oxygen molecular activation on Cr(VI) removal with core–shell Fe@Fe2O3 nanowires

    International Nuclear Information System (INIS)

    Highlights: • The presence of oxygen inhibited Cr(VI) removal efficiency with nZVI by near 3 times. • Cr(VI) removal with nZVI was related to adsorption, reduction, co-precipitation, and adsorption reactions. • Molecular oxygen activation competed donor electrons from Fe0 core and surface bound Fe(II) of nZVI. • Thicker Cr(III)/Fe(III)/Cr(VI) oxyhydroxides shell of nZVI leaded to the electron transfer inhibition. - Abstract: In this study, we demonstrate that the presence of oxygen molecule can inhibit Cr(VI) removal with core–shell Fe@Fe2O3 nanowires at neutral pH of 6.1. 100% of Cr(VI) removal was achieved by the Fe@Fe2O3 nanowires within 60 min in the anoxic condition, in contrast, only 81.2% of Cr(VI) was sequestrated in the oxic condition. Removal kinetics analysis indicated that the presence of oxygen could inhibit the Cr(VI) removal efficiency by near 3 times. XRD, SEM, and XPS analysis revealed that either the anoxic or oxic Cr(VI) removal was involved with adsorption, reduction, co-precipitation, and re-adsorption processes. More Cr(VI) was bound in a reduced state of Cr(III) in the anoxic process, while a thicker Cr(III)/Fe(III)/Cr(VI) oxyhydroxides shell, leading to inhibiting the electron transfer, was found under the oxic process. The negative impact of oxygen molecule was attributed to the oxygen molecular activation which competed with Cr(VI) adsorbed for the consumption of donor electrons from Fe0 core and ferrous ions bound on the iron oxides surface under the oxic condition. This study sheds light on the understanding of the fate and transport of Cr(VI) in oxic and anoxic environment, as well provides helpful guide for optimizing Cr(VI) removal conditions in real applications

  12. Negative impact of oxygen molecular activation on Cr(VI) removal with core–shell Fe@Fe{sub 2}O{sub 3} nanowires

    Energy Technology Data Exchange (ETDEWEB)

    Mu, Yi; Wu, Hao; Ai, Zhihui, E-mail: jennifer.ai@mail.ccnu.edu.cn

    2015-11-15

    Highlights: • The presence of oxygen inhibited Cr(VI) removal efficiency with nZVI by near 3 times. • Cr(VI) removal with nZVI was related to adsorption, reduction, co-precipitation, and adsorption reactions. • Molecular oxygen activation competed donor electrons from Fe{sup 0} core and surface bound Fe(II) of nZVI. • Thicker Cr(III)/Fe(III)/Cr(VI) oxyhydroxides shell of nZVI leaded to the electron transfer inhibition. - Abstract: In this study, we demonstrate that the presence of oxygen molecule can inhibit Cr(VI) removal with core–shell Fe@Fe{sub 2}O{sub 3} nanowires at neutral pH of 6.1. 100% of Cr(VI) removal was achieved by the Fe@Fe{sub 2}O{sub 3} nanowires within 60 min in the anoxic condition, in contrast, only 81.2% of Cr(VI) was sequestrated in the oxic condition. Removal kinetics analysis indicated that the presence of oxygen could inhibit the Cr(VI) removal efficiency by near 3 times. XRD, SEM, and XPS analysis revealed that either the anoxic or oxic Cr(VI) removal was involved with adsorption, reduction, co-precipitation, and re-adsorption processes. More Cr(VI) was bound in a reduced state of Cr(III) in the anoxic process, while a thicker Cr(III)/Fe(III)/Cr(VI) oxyhydroxides shell, leading to inhibiting the electron transfer, was found under the oxic process. The negative impact of oxygen molecule was attributed to the oxygen molecular activation which competed with Cr(VI) adsorbed for the consumption of donor electrons from Fe{sup 0} core and ferrous ions bound on the iron oxides surface under the oxic condition. This study sheds light on the understanding of the fate and transport of Cr(VI) in oxic and anoxic environment, as well provides helpful guide for optimizing Cr(VI) removal conditions in real applications.

  13. Prognostic impact of {sup 18}F-FDG PET/CT staging and of pathological response to neoadjuvant chemotherapy in triple-negative breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Groheux, D.; Merlet, P. [Saint-Louis Hospital, Department of Nuclear Medicine, Paris Cedex 10 (France); University of Paris VII, B2T Doctoral School, Institut Universitaire d' Hematologie, Paris (France); Giacchetti, S.; Hamy, A.S.; Espie, M. [Saint-Louis Hospital, Breast Diseases Unit, Department of Medical Oncology, Paris (France); Delord, M. [Institut Universitaire d' Hematologie, Department of Biostatistics and Bioinformatics, Paris (France); Roquancourt, A. de [Saint-Louis Hospital, Department of Pathology, Paris (France); Hindie, E. [University of Bordeaux, Department of Nuclear Medicine, Haut-Leveque Hospital, CHU Bordeaux, Bordeaux (France)

    2014-11-29

    Mortality is high in patients with locally advanced triple-negative breast cancer (TNBC), especially in those with residual tumour after neoadjuvant chemotherapy (NAC). The aim of this study was to determine if pretreatment {sup 18}F-FDG PET/CT staging and pathological findings after NAC could together allow stratification of patients into prognostic groups. Initial staging with {sup 18}F-FDG PET/CT was performed prospectively in 85 consecutive patients with stage II/III TNBC. Correlations between PET findings and disease-specific survival (DSS) were examined. In patients without distant metastases on PET staging, the impact of pathological response to NAC on DSS was examined. Patterns of recurrence were also analysed. {sup 18}F-DG PET/CT revealed distant metastases in 11 of 85 patients (12.9 %). Among 74 M0 patients, 23 (31.1 %) showed a pathological complete response (pCR) at surgery, while 51 had residual invasive disease (no pCR). DSS differed considerably among the three groups of patients (log-rank P <.001): among patients with occult metastases on baseline PET/CT, 2-year DSS was 18.2 %, and among patients without initial metastases on PET/CT, 5-year DSS was 61.3 % in patients without pCR after NAC and 95.2 % in those with pCR. Of the 51 patients who did not achieve pCR, 21 relapsed (17 developed distant metastases). The sites of distant recurrence were: lung/pleura (nine patients), brain (eight patients), liver (six patients), distant lymph nodes (six patients) and bone (five patients). In patients with clinical stage II/III TNBC, {sup 18}F-FDG PET/CT findings at initial staging and pathological response at the end of NAC allow three groups of patients with quite different prognoses to be defined. Extraskeletal recurrences predominated. Specific follow-up strategies in patients with TNBC who do not achieve pCR deserve investigation. (orig.)

  14. Potential Impact of a Microarray-Based Nucleic Acid Assay for Rapid Detection of Gram-Negative Bacteria and Resistance Markers in Positive Blood Cultures

    OpenAIRE

    Mancini, Nicasio; Infurnari, Laura; Ghidoli, Nadia; Valzano, Grazia; Clementi, Nicola; Burioni, Roberto; Clementi, Massimo

    2014-01-01

    We evaluated the Verigene Gram-negative blood culture (BC-GN) test, a microarray that detects Gram-negative bacteria and several resistance genes. A total of 102 positive blood cultures were tested, and the BC-GN test correctly identified 97.9% of the isolates within its panel. Resistance genes (CTX-M, KPC, VIM, and OXA genes) were detected in 29.8% of the isolates, with positive predictive values of 95.8% (95% confidence interval [CI], 87.7% to 98.9%) in Enterobacteriaceae and 100% (95% CI, ...

  15. The Impact of Positive and Negative Ecstasy-Related Information on Ecstasy Use among College Students: Results of a Longitudinal Study

    Science.gov (United States)

    Vincent, Kathryn B.; Caldeira, Kimberly M.; O'Grady, Kevin E.; Wish, Eric D.; Arria, Amelia M.

    2010-01-01

    Aims: To: (1) estimate the proportion of students exposed to specific types of information regarding the positive and negative effects of ecstasy, (2) test models that quantified the relationship between exposure to these messages and subsequent ecstasy use, controlling for peer drug use and sensation-seeking. Methods: As part of the College Life…

  16. Advertising/public relations campaign to combat the negative economic impact caused by the nuclear mishap at Three Mile Island, Pennsylvania. Final report

    International Nuclear Information System (INIS)

    The Commonwealth of Pennsylvania, through the Department of Commerce, conducted a media advertising campaign to offset the negative implications and effects of the Three Mile Island incident. The emphasis of the campaign has been directed toward a friendly, all-clear image for Pennsylvania. The travel industry of the entire Commonwealth of Pennsylvania is the chief beneficiary of the proposed project

  17. Cognitive Defusion versus Thought Distraction: A Clinical Rationale, Training, and Experiential Exercise in Altering Psychological Impacts of Negative Self-Referential Thoughts

    Science.gov (United States)

    Masuda, Akihiko; Feinstein, Amanda B.; Wendell, Johanna W.; Sheehan, Shawn T.

    2010-01-01

    Using two modes of intervention delivery, the present study compared the effects of a cognitive defusion strategy with a thought distraction strategy on the emotional discomfort and believability of negative self-referential thoughts. One mode of intervention delivery consisted of a clinical rationale and training (i.e., Partial condition). The…

  18. Advertising/public relations campaign to combat the negative economic impact caused by the nuclear mishap at Three Mile Island, Pennsylvania. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1980-10-01

    The Commonwealth of Pennsylvania, through the Department of Commerce, conducted a media advertising campaign to offset the negative implications and effects of the Three Mile Island incident. The emphasis of the campaign has been directed toward a friendly, all-clear image for Pennsylvania. The travel industry of the entire Commonwealth of Pennsylvania is the chief beneficiary of the proposed project.

  19. Negativity in Massive Online Open Courses: Impacts on Learning and Teaching and How Instructional Teams May Be Able to Address It

    Science.gov (United States)

    Comer, Denise; Baker, Ryan; Wang, Yuan

    2015-01-01

    There are many positive aspects of teaching and learning in Massive Online Open Courses (MOOCs), for both instructors and students. However, there is also a considerable amount of negativity in MOOCs, emerging from learners on discussion forums and through peer assessment, from disciplinary colleagues and from public discourse around MOOCs.…

  20. The impact of CBT training and supervision on burnout, confidence and negative beliefs in a staff group working with homeless people

    OpenAIRE

    Maguire, N.; Grellier, B.; Clayton, K.

    2012-01-01

    This study reports the outcomes of providing training and regular clinical supervision in basic cognitive-behavioural formulation and intervention techniques for frontline homelessness workers. Results indicated that confidence increased and negative beliefs decreased at the end of the training, and continued to decrease as a result of the supervision package. Burnout significantly decreased after the training and supervision package.

  1. Negative pressure wound therapy : treatment outcomes and the impact on the patient´s health-related quality of life

    OpenAIRE

    Fagerdahl, Ann-Mari

    2013-01-01

    Throughout history wounds have been a cause of great distress to the sufferer and a major burden to society. Especially the slow-healing wounds have been an issue and in order to find healing treatments, complementary methods have been developed. Negative pressure wound therapy (NPWT) is one such complementary method. The overall aim of this thesis was to study if NPWT is an effective and safe method for wound treatment and to enhance the knowledge of the patients’ experience of the treatment...

  2. "Disorganized in time": impact of bottom-up and top-down negative emotion generation on memory formation among healthy and traumatized adolescents.

    Science.gov (United States)

    Guillery-Girard, Bérengère; Clochon, Patrice; Giffard, Bénédicte; Viard, Armelle; Egler, Pierre-Jean; Baleyte, Jean-Marc; Eustache, Francis; Dayan, Jacques

    2013-09-01

    "Travelling in time," a central feature of episodic memory is severely affected among individuals with Post Traumatic Stress Disorder (PTSD) with two opposite effects: vivid traumatic memories are unorganized in temporality (bottom-up processes), non-traumatic personal memories tend to lack spatio-temporal details and false recognitions occur more frequently that in the general population (top-down processes). To test the effect of these two types of processes (i.e. bottom-up and top-down) on emotional memory, we conducted two studies in healthy and traumatized adolescents, a period of life in which vulnerability to emotion is particularly high. Using negative and neutral images selected from the international affective picture system (IAPS), stimuli were divided into perceptual images (emotion generated by perceptual details) and conceptual images (emotion generated by the general meaning of the material). Both categories of stimuli were then used, along with neutral pictures, in a memory task with two phases (encoding and recognition). In both populations, we reported a differential effect of the emotional material on encoding and recognition. Negative perceptual scenes induced an attentional capture effect during encoding and enhanced the recollective distinctiveness. Conversely, the encoding of conceptual scenes was similar to neutral ones, but the conceptual relatedness induced false memories at retrieval. However, among individuals with PTSD, two subgroups of patients were identified. The first subgroup processed the scenes faster than controls, except for the perceptual scenes, and obtained similar performances to controls in the recognition task. The second subgroup group desmonstrated an attentional deficit in the encoding task with no benefit from the distinctiveness associated with negative perceptual scenes on memory performances. These findings provide a new perspective on how negative emotional information may have opposite influences on memory in

  3. Three-dimensional modeling of a negative ion source with a magnetic filter: impact of biasing the plasma electrode on the plasma asymmetry

    Science.gov (United States)

    Fubiani, G.; Boeuf, J. P.

    2015-10-01

    The effect on the plasma characteristics of biasing positively the plasma electrode (PE) in negative ion sources with a magnetic filter is analysed using a 3D particle-in-cell model with Monte-Carlo collisions (PIC-MCC). We specialize to the one driver (i.e. one inductively coupled radio-frequency discharge) BATMAN negative ion source and the 4-drivers (large volume) ELISE device. Both are ITER prototype high power tandem-type negative ion sources developed for the neutral beam injector (NBI) system. The plasma is generated in the driver and diffuses inside the second chamber which is magnetized. Asymmetric plasma profiles originate from the formation of an electric field transverse to the electron current flowing through the magnetic filter (Hall effect). The model shows that the importance of the asymmetry increases with the PE bias potential, i.e. with the electron flow from the driver to the extraction region and depends on the shape of the magnetic filter field. We find that although the plasma density and potential profiles may be more or less asymmetric depending on the filter field configuration, the electron current to the plasma grid is always strongly asymmetric.

  4. Negative Attitudes, Network and Education

    OpenAIRE

    Bennett, Patrick; La Cour, Lisbeth; Larsen, Birthe; Waisman, Gisela

    2015-01-01

    This paper explores potential explanations behind the educational gap between young natives and immigrants using two measures, negative attitudes towards immigrants and networking, which may influence natives and immigrants differently. The paper considers, both theoretically and empirically, the impact of negative attitudes and networking taking into account that these parameters may influence high and uneducated workers as well as immigrants and natives differently, creating different incen...

  5. The Negative Environmental Changes on the Sea and its Impact on the Aspects of Economic, Social and Health of the Fishermen Living in the East Coast Zone of Peninsular Malaysia

    Directory of Open Access Journals (Sweden)

    Bahaman A. Samah

    2011-01-01

    Full Text Available Problem statement: The sea has never been the same as before. Due to the environment and human factors, lot of negative environmental changes can be detected at the sea. Apparently, one of the main dependents of the sea which is the fishermen has the potential to be affected with such changes. Approach: This study would like to discover whether these changes have affected the aspects of economic, social and health of the fishermen living in the east coast zone of Peninsular Malaysia. This is a quantitative study where a total of 300 fishermen have been selected as the respondents. The number was gained from four states in the east coast zone of Peninsular Malaysia namely Kelantan, Terengganu, Pahang and East Johor. Results: The instrument used for this study is a developed questionnaire that was pre tested earlier before the actual data collection conducted. To gain the data needed, survey was employed. Based on the results gained it can be seen that the negative environmental changes that occurs on the sea have moderately affected the aspects of economic, social and health of the fishermen living in the east coast zone of Peninsular Malaysia. Conclusion/Recommendations: It is recommended that the fishermen all over Malaysia should be provided with information on the potential impacts of the negative environmental changes on the sea so that they can prepare themselves to face these negative changes.

  6. Negative Attitudes, Network and Education

    DEFF Research Database (Denmark)

    Bennett, Patrick; la Cour, Lisbeth; Larsen, Birthe;

    This paper explores potential explanations behind the educational gap between young natives and immigrants using two measures, negative attitudes towards immigrants and networking, which may influence natives and immigrants differently. The paper considers, both theoretically and empirically, the...... impact of negative attitudes and networking taking into account that these parameters may influence high and uneducated workers as well as immigrants and natives differently, creating different incentives to acquire education for the two ethnic groups. Using rich Danish administrative data, this paper...... finds evidence that greater negative attitudes increase incentives for males to acquire education and that networking also increases immigrant education....

  7. Prognostic Value of Molecular Subtypes, Ki67 Expression and Impact of Postmastectomy Radiation Therapy in Breast Cancer Patients With Negative Lymph Nodes After Mastectomy

    International Nuclear Information System (INIS)

    Purpose: To determine whether Ki67 expression and breast cancer subtypes could predict locoregional recurrence (LRR) and influence the postmastectomy radiotherapy (PMRT) decision in breast cancer (BC) patients with pathologic negative lymph nodes (pN0) after modified radical mastectomy (MRM). Methods and Materials: A total of 699 BC patients with pN0 status after MRM, treated between 2001 and 2008, were identified from a prospective database in a single institution. Tumors were classified by intrinsic molecular subtype as luminal A or B, HER2+, and triple-negative (TN) using estrogen, progesterone, and HER2 receptors. Multivariate Cox analysis was used to determine the risk of LRR associated with intrinsic subtypes and Ki67 expression, adjusting for known prognostic factors. Results: At a median follow-up of 56 months, 17 patients developed LRR. Five-year LRR-free survival and overall survival in the entire population were 97%, and 94.7%, respectively, with no difference between the PMRT (n=191) and no-PMRT (n=508) subgroups. No constructed subtype was associated with an increased risk of LRR. Ki67 >20% was the only independent prognostic factor associated with increased LRR (hazard ratio, 4.18; 95% CI, 1.11-15.77; P<.0215). However, PMRT was not associated with better locoregional control in patients with proliferative tumors. Conclusions: Ki67 expression but not molecular subtypes are predictors of locoregional recurrence in breast cancer patients with negative lymph nodes after MRM. The benefit of adjuvant RT in patients with proliferative tumors should be further investigated in prospective studies.

  8. Prognostic Value of Molecular Subtypes, Ki67 Expression and Impact of Postmastectomy Radiation Therapy in Breast Cancer Patients With Negative Lymph Nodes After Mastectomy

    Energy Technology Data Exchange (ETDEWEB)

    Selz, Jessica, E-mail: chaumontjessica@yahoo.fr [Department of Radiation Oncology, Institut Curie, Hopital Rene Huguenin, Saint Cloud (France); Stevens, Denise; Jouanneau, Ludivine [Department of Medical Statistics, Institut Curie, Hopital Rene Huguenin, Saint Cloud (France); Labib, Alain [Department of Radiation Oncology, Institut Curie, Hopital Rene Huguenin, Saint Cloud (France); Le Scodan, Romuald [Department of Radiation Oncology, Centre Hospitalier Prive Saint Gregoire, Saint Gregoire (France)

    2012-12-01

    Purpose: To determine whether Ki67 expression and breast cancer subtypes could predict locoregional recurrence (LRR) and influence the postmastectomy radiotherapy (PMRT) decision in breast cancer (BC) patients with pathologic negative lymph nodes (pN0) after modified radical mastectomy (MRM). Methods and Materials: A total of 699 BC patients with pN0 status after MRM, treated between 2001 and 2008, were identified from a prospective database in a single institution. Tumors were classified by intrinsic molecular subtype as luminal A or B, HER2+, and triple-negative (TN) using estrogen, progesterone, and HER2 receptors. Multivariate Cox analysis was used to determine the risk of LRR associated with intrinsic subtypes and Ki67 expression, adjusting for known prognostic factors. Results: At a median follow-up of 56 months, 17 patients developed LRR. Five-year LRR-free survival and overall survival in the entire population were 97%, and 94.7%, respectively, with no difference between the PMRT (n=191) and no-PMRT (n=508) subgroups. No constructed subtype was associated with an increased risk of LRR. Ki67 >20% was the only independent prognostic factor associated with increased LRR (hazard ratio, 4.18; 95% CI, 1.11-15.77; P<.0215). However, PMRT was not associated with better locoregional control in patients with proliferative tumors. Conclusions: Ki67 expression but not molecular subtypes are predictors of locoregional recurrence in breast cancer patients with negative lymph nodes after MRM. The benefit of adjuvant RT in patients with proliferative tumors should be further investigated in prospective studies.

  9. Leukaemia inhibitory factor (LIF) gene mutations in women diagnosed with unexplained infertility and endometriosis have a negative impact on the IVF outcome a pilot study

    Czech Academy of Sciences Publication Activity Database

    Novotný, Z.; Křižan, Jiří; Šíma, R.; Šíma, Petr; Uher, P.; Zech, N.; Huttelová, R.; Baborová, P.; Ulčová-Gallová, Z.; Šubrt, I.; Ulmanová, E.; Houdek, Z.; Rokyta, Z.; Babuška, V.; Králíčková, M.

    2009-01-01

    Roč. 55, č. 3 (2009), s. 92-97. ISSN 0015-5500 R&D Projects: GA MZd NR9135 Institutional research plan: CEZ:AV0Z50200510 Keywords : leukaemia inhibitory factor * infertility * mutation Subject RIV: EC - Immunology Impact factor: 0.924, year: 2009

  10. Does the nutrition profile of vitamins, fatty acids and microelements counteract the negative impact from organohalogen pollutants on bone mineral density in Greenland sledge dogs (Canis familiaris)?

    DEFF Research Database (Denmark)

    Sonne, Christian; Riget, Frank F.; Jensen, Jens-Erik Beck;

    2008-01-01

    There is a great need for understanding the impact from dietary OHCs (organohalogen compounds) on bone mineral composition - and thereby osteoporosis - in especially arctic wildlife such as polar bears (Ursus maritimus) as well as humans. For that purpose, we measured BMD (bone mineral density) by...... polluted marine species. (C) 2008 Elsevier Ltd. All rights reserved....

  11. A brief report on the illegal cage-bird trade in southern Florida: a potentially serious negative impact on the eastern population of Painted Bunting (Passerina ciris)

    Science.gov (United States)

    Sykes, P.W., Jr.; Manfredi, L.; Padura, M.

    2006-01-01

    Populations of Painted Bunting (Passerina ciris) have been declining annually over the past 35 years. A cursory survey indicates that illegal trapping of Painted Buntings for a black market cage-bird trade is widespread in southeastern Florida. Coupled with other negative factors confronting the eastern population, the trapping of buntings for the cagebird trade may, in time, produce dire results for this native songbird. Law enforcement personnel need to continue to monitor the illegal activity of trapping native passerines for the local songbird market and to continue to arrest those who support it.

  12. On French negation

    NARCIS (Netherlands)

    H. Zeijlstra

    2009-01-01

    Two main characteristics of French negation are (i) that the language is a so-called Negative Concord (NC) language; and (ii) that French exhibits so-called embracing negation. NC refers to the phenomenon where multiple negative expressions yield only one negation. Embracing negation means that the

  13. Media and technology use predicts ill-being among children, preteens and teenagers independent of the negative health impacts of exercise and eating habits

    OpenAIRE

    Rosen, L.D.; Lim, A.F.; Felt, J.; Carrier, L.M.; Cheever, N.A.; Lara-Ruiz, J.M.; Mendoza, J.S.; Rokkum, J.

    2014-01-01

    The American Academy of Pediatrics recommends no screen time for children under the age of 2 and limited screen time for all children. However, no such guidelines have been proposed for preteens and teenagers. Further, research shows that children, preteens, and teenagers are using massive amounts of media and those with more screen time have been shown to have increased obesity, reduced physical activity, and decreased health. This study examined the impact of technology on four areas of ill...

  14. 高校就业工作中同龄人压力的负面影响及对策研究%Research on the Negative Impact of Peer Pressure on Graduate Employment and Related Countermeasures

    Institute of Scientific and Technical Information of China (English)

    谢家荣; 耿佃梅

    2014-01-01

    群体性是高校大学生的显著特点。通过引入同龄人压力这一心理学概念,分析同龄人压力对高校毕业生就业工作带来的负面影响,并提出解决对策。%Group collectivism is a distinctive feature of college students. By introducing the psychological concept of peer pressure, the article analyzes its negative impact on college students in their job seeking process and proposes related countermeasures.

  15. Selection for increased muscling in Angus cattle did not increase the glycolytic potential or negatively impact pH decline, retail colour stability or mineral content.

    Science.gov (United States)

    McGilchrist, P; Greenwood, P L; Pethick, D W; Gardner, G E

    2016-04-01

    This study determined the impact of selection for greater muscling in Angus cattle on myofibre characteristics, muscle enzymatics, retail colour stability, pH decline and mineral content of the semimembranosus (SM), semitendinosus (ST) and longissimus thoracis (LT). Muscle from 10 low muscled (low) and 11 high muscled (high) steers were analysed. The high steers had myofibres 22% and 24% larger in cross-sectional area in the SM and ST (Pmuscle can be maintained in more muscular cattle with no detrimental effects to mineral content, pH decline or retail colour stability. Myofibre hypertrophy is one mechanism leading to greater muscle mass of these high muscled cattle. PMID:26720886

  16. Polemic and Descriptive Negations

    DEFF Research Database (Denmark)

    Horslund, Camilla Søballe

    2011-01-01

    semantics and pragmatics, negations can be used in three different ways, which gives rise to a typology of three different types of negations: 1) the descriptive negation, 2) the polemic negation, and 3) the meta-linguistic negation (Nølke 1999, 4). This typology illuminates the fact that the negation as...... meaning of the utterance (as in polemic negations), the negation will be articulated prominently in order to emphasise this importance. Likewise, if the negation is not central to the meaning of the utterance, it should not be articulated prominently. Moreover, it is plausible to expect descriptive...

  17. Target-site resistance mutations (kdr and RDL), but not metabolic resistance, negatively impact male mating competiveness in the malaria vector Anopheles gambiae.

    Science.gov (United States)

    Platt, N; Kwiatkowska, R M; Irving, H; Diabaté, A; Dabire, R; Wondji, C S

    2015-09-01

    The implementation of successful insecticide resistance management strategies for malaria control is currently hampered by poor understanding of the fitness cost of resistance on mosquito populations, including their mating competiveness. To fill this knowledge gap, coupled and uncoupled Anopheles gambiae s.l. males (all M form (Anopheles coluzzii)) were collected from mating swarms in Burkina Faso. This multiple insecticide resistant population exhibited high 1014F kdr(R) allele frequencies (>60%) and RDL(R) (>80%) in contrast to the Ace-1(R) allele (RDL(R)/RDL(S) were also more likely to mate than homozygote-resistant males (OR=2.58; P=0.007). Furthermore, an additive mating disadvantage was detected in male homozygotes for both kdr/RDL-resistant alleles. In contrast, no fitness difference was observed for the Ace-1 mutation. Comparative microarray-based genome-wide transcription analysis revealed that metabolic resistance did not significantly alter the mating competitiveness of male An. coluzzii mosquitoes. Indeed, no significant difference of expression levels was observed for the main metabolic resistance genes, suggesting that metabolic resistance has a limited impact on male mating competiveness. In addition, specific gene classes/GO terms associated with mating process were detected including sensory perception and peroxidase activity. The detrimental impact of insecticide resistance on mating competiveness observed here suggests that resistance management strategies such as insecticide rotation could help reverse the resistance, if implemented early. PMID:25899013

  18. Dissecting the regulatory microenvironment of a large animal model of non-Hodgkin lymphoma: evidence of a negative prognostic impact of FOXP3+ T cells in canine B cell lymphoma.

    Directory of Open Access Journals (Sweden)

    Dammy Pinheiro

    Full Text Available The cancer microenvironment plays a pivotal role in oncogenesis, containing a number of regulatory cells that attenuate the anti-neoplastic immune response. While the negative prognostic impact of regulatory T cells (Tregs in the context of most solid tissue tumors is well established, their role in lymphoid malignancies remains unclear. T cells expressing FOXP3 and Helios were documented in the fine needle aspirates of affected lymph nodes of dogs with spontaneous multicentric B cell lymphoma (BCL, proposed to be a model for human non-Hodgkin lymphoma. Multivariable analysis revealed that the frequency of lymph node FOXP3(+ T cells was an independent negative prognostic factor, impacting both progression-free survival (hazard ratio 1.10; p = 0.01 and overall survival (hazard ratio 1.61; p = 0.01 when comparing dogs showing higher than the median FOXP3 expression with those showing the median value of FOXP3 expression or less. Taken together, these data suggest the existence of a population of Tregs operational in canine multicentric BCL that resembles thymic Tregs, which we speculate are co-opted by the tumor from the periphery. We suggest that canine multicentric BCL represents a robust large animal model of human diffuse large BCL, showing clinical, cytological and immunophenotypic similarities with the disease in man, allowing comparative studies of immunoregulatory mechanisms.

  19. Negative Pressure Wound Therapy Literature Review of Efficacy, Cost Effectiveness, and Impact on Patients' Quality of Life in Chronic Wound Management and Its Implementation in the United Kingdom

    Directory of Open Access Journals (Sweden)

    Diaa Othman

    2012-01-01

    Full Text Available This is a paper reviewing the National Health Service (NHS agenda in relation to the use of Negative Pressure Wound Therapy (NPWT in chronic wound management and assesses the evidence behind it, its cost effectiveness and the outcome it has on patients’ satisfaction and life style. Multiple studies over the last 10 years looking at clinical efficacy of NPWT with its cost effectiveness and the implementation of this service in the UK were reviewed. NPWT has showed a reasonable body of evidence to support its usage in chronic wounds with potential positive outcomes on finance and patients’ satisfaction. However, the NHS system shows significant variations in the availability and implementation of this useful tool, depending on care providers and resources availabilities. The paper concluded that the NPWT can be a useful source of cutting down costs of chronic wound managements and saving money by its effect on expediting wound healing, which can address a part of the financial crises facing the NHS, however, has to be considered according to specific case needs. There should also be a national standard for the availability and indication of this tool to assure equal opportunities for different patients in different areas in the country.

  20. Do you get where I'm coming from?: Perceived understanding buffers against the negative impact of conflict on relationship satisfaction.

    Science.gov (United States)

    Gordon, Amie M; Chen, Serena

    2016-02-01

    Conflict can have damaging effects on relationship health. But is all conflict detrimental? Across 7 studies, we tested the overarching hypothesis that conflict in close relationships is only detrimental when people do not feel their thoughts, feelings, and point of view are understood by their relationship partners. Supporting this, conflict was negatively associated with relationship satisfaction among participants who perceived their romantic partner as less understanding, but not among those who felt more understood by their partners. This was true cross-sectionally (Study 1), experimentally (Studies 2, 3, 6a, and 6b), in daily life (Study 4), and for both members of couples pre- to postconflict conversation in the laboratory (Study 5). The buffering effects of feeling understood could not be explained by people who felt more understood being more understanding themselves, having more general positive perceptions of their partners, fighting about less important or different types of issues, engaging in more pleasant conflict conversations, or being more satisfied with their relationships before the conflict. Perceived understanding was positively associated with conflict resolution, but this did not explain the benefits of feeling understood. Evidence from Studies 6a and 6b suggests that feeling understood during conflict may buffer against reduced relationship satisfaction in part because it strengthens the relationship and signals that one's partner is invested. Overall, these studies suggest that perceived understanding may be a critical buffer against the potentially detrimental effects of relationship conflict. PMID:26523997

  1. Personality, Negativity, and Political Participation

    Directory of Open Access Journals (Sweden)

    Aaron C. Weinschenk

    2014-08-01

    Full Text Available Scholars have recently started to integrate personality traits into models of political participation. In this paper, we present the results of a survey experiment (N = 724 designed to test whether negative political messages differentially impact people with different personality traits. We found evidence that individuals with high scores on agreeableness were less likely, and individuals with high scores on extraversion were more likely, to report intending to participate in politics than their counterparts after being exposed to negative political messages. Agreeableness and extraversion also interacted with negative messages to influence specific intentions to make a political donation, attend a meeting, rally, or event, and volunteer for a political campaign. We also found suggestive evidence that agreeableness interacted with negativity to influence turnout intentions. The results of this study have important implications for the study of political engagement, the ways in which people interact with political information, and the practice of democratic politics.

  2. Impact of Consolidation Radiation Therapy in Stage III-IV Diffuse Large B-cell Lymphoma With Negative Post-Chemotherapy Radiologic Imaging

    International Nuclear Information System (INIS)

    Purpose: While consolidation radiation therapy (i.e., RT administered after chemotherapy) is routine treatment for patients with early-stage diffuse large B-cell lymphoma (DLBCL), the role of consolidation RT in stage III-IV DLBCL is controversial. Methods and Materials: Cases of patients with stage III-IV DLBCL treated from 1991 to 2009 at Duke University, who achieved a complete response to chemotherapy were reviewed. Clinical outcomes were calculated using the Kaplan-Meier method and were compared between patients who did and did not receive RT, using the log-rank test. A multivariate analysis was performed using Cox proportional hazards model. Results: Seventy-nine patients were identified. Chemotherapy (median, 6 cycles) consisted of anti-CD20 antibody rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP; 65%); cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP; 22%); or other (13%). Post-chemotherapy imaging consisted of positron emission tomography (PET)/computed tomography (CT) (73%); gallium with CT (14%); or CT only (13%). Consolidation RT (median, 25 Gy) was given to involved sites of disease in 38 (48%) patients. Receipt of consolidation RT was associated with improved in-field control (92% vs. 69%, respectively, p = 0.028) and event-free survival (85% vs. 65%, respectively, p = 0.014) but no difference in overall survival (85% vs. 78%, respectively, p = 0.15) when compared to patients who did not receive consolidation RT. On multivariate analysis, no RT was predictive of increased risk of in-field failure (hazard ratio [HR], 8.01, p = 0.014) and worse event-free survival (HR, 4.3, p = 0.014). Conclusions: Patients with stage III-IV DLBCL who achieve negative post-chemotherapy imaging have improved in-field control and event-free survival with low-dose consolidation RT.

  3. Impact of Consolidation Radiation Therapy in Stage III-IV Diffuse Large B-cell Lymphoma With Negative Post-Chemotherapy Radiologic Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Dorth, Jennifer A., E-mail: jennifer.dorth@duke.edu [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Prosnitz, Leonard R. [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Broadwater, Gloria [Cancer Statistical Center, Duke University Medical Center, Durham, North Carolina (United States); Diehl, Louis F.; Beaven, Anne W. [Department of Medicine, Division of Medical Oncology, Duke University Medical Center, Durham, North Carolina (United States); Coleman, R. Edward [Department of Radiology, Division of Nuclear Medicine, Duke University Medical Center, Durham, North Carolina (United States); Kelsey, Chris R. [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States)

    2012-11-01

    Purpose: While consolidation radiation therapy (i.e., RT administered after chemotherapy) is routine treatment for patients with early-stage diffuse large B-cell lymphoma (DLBCL), the role of consolidation RT in stage III-IV DLBCL is controversial. Methods and Materials: Cases of patients with stage III-IV DLBCL treated from 1991 to 2009 at Duke University, who achieved a complete response to chemotherapy were reviewed. Clinical outcomes were calculated using the Kaplan-Meier method and were compared between patients who did and did not receive RT, using the log-rank test. A multivariate analysis was performed using Cox proportional hazards model. Results: Seventy-nine patients were identified. Chemotherapy (median, 6 cycles) consisted of anti-CD20 antibody rituximab combined with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP; 65%); cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP; 22%); or other (13%). Post-chemotherapy imaging consisted of positron emission tomography (PET)/computed tomography (CT) (73%); gallium with CT (14%); or CT only (13%). Consolidation RT (median, 25 Gy) was given to involved sites of disease in 38 (48%) patients. Receipt of consolidation RT was associated with improved in-field control (92% vs. 69%, respectively, p = 0.028) and event-free survival (85% vs. 65%, respectively, p = 0.014) but no difference in overall survival (85% vs. 78%, respectively, p = 0.15) when compared to patients who did not receive consolidation RT. On multivariate analysis, no RT was predictive of increased risk of in-field failure (hazard ratio [HR], 8.01, p = 0.014) and worse event-free survival (HR, 4.3, p = 0.014). Conclusions: Patients with stage III-IV DLBCL who achieve negative post-chemotherapy imaging have improved in-field control and event-free survival with low-dose consolidation RT.

  4. Revised Big Bang Nucleosynthesis with Long-lived, Negatively Charged Massive Particles: Updated Recombination Rates, Primordial 9Be Nucleosynthesis, and Impact of New 6Li Limits

    Science.gov (United States)

    Kusakabe, Motohiko; Kim, K. S.; Cheoun, Myung-Ki; Kajino, Toshitaka; Kino, Yasushi; Mathews, Grant. J.

    2014-09-01

    We extensively reanalyze the effects of a long-lived, negatively charged massive particle, X -, on big bang nucleosynthesis (BBN). The BBN model with an X - particle was originally motivated by the discrepancy between the 6, 7Li abundances predicted in the standard BBN model and those inferred from observations of metal-poor stars. In this model, 7Be is destroyed via the recombination with an X - particle followed by radiative proton capture. We calculate precise rates for the radiative recombinations of 7Be, 7Li, 9Be, and 4He with X -. In nonresonant rates, we take into account respective partial waves of scattering states and respective bound states. The finite sizes of nuclear charge distributions cause deviations in wave functions from those of point-charge nuclei. For a heavy X - mass, mX >~ 100 GeV, the d-wave → 2P transition is most important for 7Li and 7, 9Be, unlike recombination with electrons. Our new nonresonant rate of the 7Be recombination for mX = 1000 GeV is more than six times larger than the existing rate. Moreover, we suggest a new important reaction for 9Be production: the recombination of 7Li and X - followed by deuteron capture. We derive binding energies of X nuclei along with reaction rates and Q values. We then calculate BBN and find that the amount of 7Be destruction depends significantly on the charge distribution of 7Be. Finally, updated constraints on the initial abundance and the lifetime of the X - are derived in the context of revised upper limits to the primordial 6Li abundance. Parameter regions for the solution to the 7Li problem and the primordial 9Be abundances are revised.

  5. REVISED BIG BANG NUCLEOSYNTHESIS WITH LONG-LIVED, NEGATIVELY CHARGED MASSIVE PARTICLES: UPDATED RECOMBINATION RATES, PRIMORDIAL 9Be NUCLEOSYNTHESIS, AND IMPACT OF NEW 6Li LIMITS

    International Nuclear Information System (INIS)

    We extensively reanalyze the effects of a long-lived, negatively charged massive particle, X –, on big bang nucleosynthesis (BBN). The BBN model with an X – particle was originally motivated by the discrepancy between the 6, 7Li abundances predicted in the standard BBN model and those inferred from observations of metal-poor stars. In this model, 7Be is destroyed via the recombination with an X – particle followed by radiative proton capture. We calculate precise rates for the radiative recombinations of 7Be, 7Li, 9Be, and 4He with X –. In nonresonant rates, we take into account respective partial waves of scattering states and respective bound states. The finite sizes of nuclear charge distributions cause deviations in wave functions from those of point-charge nuclei. For a heavy X – mass, mX ≳ 100 GeV, the d-wave → 2P transition is most important for 7Li and 7, 9Be, unlike recombination with electrons. Our new nonresonant rate of the 7Be recombination for mX = 1000 GeV is more than six times larger than the existing rate. Moreover, we suggest a new important reaction for 9Be production: the recombination of 7Li and X – followed by deuteron capture. We derive binding energies of X nuclei along with reaction rates and Q values. We then calculate BBN and find that the amount of 7Be destruction depends significantly on the charge distribution of 7Be. Finally, updated constraints on the initial abundance and the lifetime of the X – are derived in the context of revised upper limits to the primordial 6Li abundance. Parameter regions for the solution to the 7Li problem and the primordial 9Be abundances are revised

  6. Health Technology Assessment of the Negative Pressure Wound Therapy for the treatment of acute and chronic wounds: efficacy, safety, cost effectiveness, organizational and ethical impact

    Directory of Open Access Journals (Sweden)

    Paolo Giorgi Rossi

    2012-06-01

    Full Text Available

    Background: the aim of the study was to assess the safety, efficacy and cost-effectiveness of negative Pressure wound therapy (nPT for people with chronic and acute wounds.

    Methods: the scope and the final draft of the report have been submitted to the stakeholders (producers, payers and patients. safety issues were addressed through a systematic review of the meta-literature. efficacy was addressed through a systematic review and meta-analysis of randomized controlled trials (rcTs comparing nPT and other standard therapies in patients with chronic or acute lesions. cost-consequence was analyzed through a systematic review of the existing studies.

    Results: we retrieved 19 studies, 13 of which were included in the meta-analysis. Many studies had biases that may have resulted in a better performance for nPT. nPT showed: a slightly shorter healing time (-10.4 days, p=0.001, with no heterogeneity, apart from one small study with very positive results, and 40% more patients healed (p=0.002, no heterogeneity.We identified 15 original research papers on nPT costs and cost per outcome. The costs-per-patient- treated varied from +29% to -60%, with several studies reporting savings for nPT.

    Conclusions: despite serious methodological flaws, the body of evidence available was sufficient to prove some clinical benefit of nPT in severe chronic and acute wound treatment. There is a need for independent and contextualized cost analyses....

  7. Forecasting Winter Storms in the Sierra: A Social Science Perspective in Keeping the Public Safe without Negatively Impacting the Local Tourism Industry

    Science.gov (United States)

    Milne, R.; Wallmann, J.; Myrick, D. T.

    2010-12-01

    The National Weather Service Office in Reno is responsible for issuing Blizzard Warnings, Winter Storm Warnings, and Winter Weather Advisories for the Sierra, including the Lake Tahoe Basin and heavily traveled routes such as Interstate 80, Highway 395 and Highway 50. These forecast products prepare motorists for harsh travel conditions as well as those venturing into the backcountry, which are essential to the NWS mission of saving lives and property. During the winter season, millions of people from around the world visit the numerous world class ski resorts in the Sierra and the Lake Tahoe Basin, which is vital to the local economy. This situation creates a challenging decision for the forecasters to provide appropriate wording in winter statements to keep the public safe, without significantly impacting the local tourism-based economy. Numerous text and graphical products, including online weather briefings, are utilized by NWS Reno to highlight hazards in ensuring the public, businesses, and other government agencies are prepared for winter storms and take appropriate safety measures. The effectiveness of these product types will be explored, with past snowstorms used as examples to show how forecasters determine which type of text or graphical product is most appropriate to convey the hazardous weather threats.

  8. Negative impact on growth and photosynthesis in the green alga Chlamydomonas reinhardtii in the presence of the estrogen 17α-ethynylestradiol.

    Directory of Open Access Journals (Sweden)

    Tessa Pocock

    Full Text Available It is well known that estrogenic compounds affect development of fertilized eggs of many species of birds, fish and amphibians through disrupted activity of carbonic anhydrase (CA. The most potent activity comes from the most commonly occurring synthetic sterol, 17α-Ethynylestradiol (EE2. Less is known about the responses of aquatic phytoplankton to these compounds. Here we show for the first time that, in comparision to the control, the addition of 7 µM EE2 reduced the growth rate of the green alga Chlamydomonas reinhardtii by 68% for cells grown at high CO2. When cells were grown in ambient air (low Ci with a fully activated carbon concentrating mechanism through the induction of CA activity, the growth rates were reduced by as much as 119%. A reduced growth rate could be observed at EE2 concentrations as low as 10 pM. This was accompanied by a reduced maximum capacity for electron transport in photosystem II as determined by a lower FV/FM for low Ci-grown cells, which indicates the involvement of CAH3, a CA specifically located in the thylakoid lumen involved in proton pumping across the thylakoid membranes. These results were in agreement with an observed reduction in the chloroplastic affinity for Ci as shown by a strong increase in the Michaelis-Menten K0.5 for HCO3-. In itself, a lowering of the growth rate of a green alga by addition of the sterol EE2 warrants further investigation into the potential environmental impact by the release of treated waste water.

  9. What Negative Impact does Wind have on the Deadline of a Construction Project? Mathematical Modeling for the Measurement and Optimization of Wind Effects

    Directory of Open Access Journals (Sweden)

    Adil Hafidi Alaoui

    2015-10-01

    Full Text Available In regard to economic phenomena such as the expansion of trade, the interactions between markets encouraging companies to cross borders, the research for market in new areas should be accompanied by sufficient knowledge of their own environment and especially the weather conditions. Indeed, the objectives of a construction project (cost, deadline and quality are affected by a multitude of events, of internal and external origin, such as climate changes when they are severe and abrupt. Certainly, each region is characterized by a specific climate. For some regions, it is rather the wind that remains the most characterizing climate factor. Wind is widely felt in areas exposed to currents such as (trade wind, North wind, Nordet, Harmattan etc…, in other places we underestimate, see, ignore the effects of wind, particularly on a construction site. Yet, the consequences of ignoring this risk factor can be heavy on a construction company (in terms of late penalty law for example; In fact, if bad weather affects particularly on the initial works: earthworks, foundations, slab; wind effects may proclaim during all the duration of the construction site. The wind affect all project’s aspects, quality, cost, safety as well as deadline. Nevertheless there are few studies that were interested in studying relation construction‘s deadline and wind. Tangier, the city located on the Strait of Gibraltar, where the study was conducted, is exposed to wind whose origin is the Anti cyclone of the Azores, in addition to the local winds that are due to the presence of the two seas and imposing mountains, with a wind that might exceed 220km/h. The equation introduced by this study will allow evaluating (measuring the impact of wind on the deadline (expressed Δ, it shall encompass all aspects: - Limiting conditions of equipments existing in construction site (producers’ references - Recommendations of the standard practice - Regulation in terms of work

  10. Negating the Verum

    DEFF Research Database (Denmark)

    Ørsnes, Bjarne

    2012-01-01

    complementizer and the subject. This little-studied phenomenon is referred to as preposed negation. The article investigates the syntax and semantics of preposed negation from a primarily descriptive point of view. It is argued that preposed negation is associated with negated verum-focus of a clause lacking an...... (aboutness-)topic. The negation of a verum predicate explains why preposed negation—like other constructions with verum-focus—fails to license strong negative polarity items and fails to rule out positive ones. The lack of a topic explains why preposed negation is preferred with non-referential subjects and...

  11. Digital Publishing Negative Impact of Personalized Service and Its Control%数字出版个性化服务的负面影响及其控制研究

    Institute of Scientific and Technical Information of China (English)

    周斌

    2013-01-01

    Early development of digital publi shing do always meet consumer demand, readers are considered as the center in the process of content production services, profit is the purpose of the business model, maximizing of freedom and opening up is the objective of construction of self-media platform, these have a certain negative impact on reading depth, grade of cultural consumption and media ecology. From the perspective of construction of the media ecology and publishing culture, research initiatives to control digital publishing negative impact of personalized service, protection authority, civilized and effective information dissemination, maintenance ecology of publishing culture, to avoid the development of digital publishing industry into a “grow first, clean up later” cycle.%数字出版发展初期没有节制地迎合读者消费需求,以读者为中心进行内容生产服务,以营利为目的进行经营模式设计,以追求自由开放最大化为目标进行自媒体平台建设,会对读者阅读深度、文化消费品位和媒介生态产生一定负面影响。从媒介生态构建和出版文化建设角度研究举措,控制数字出版个性化服务的负面影响,保障权威、文明和有效的信息传播,维护出版文化生态,以避免数字出版业的发展陷入“先发展,后治理”的怪圈。

  12. 医保基金风险责任转嫁医疗机构负面影响分析%Analysis of Negative Impact from Health-insurance Funds Shifting Their Risks to Medical Institutions

    Institute of Scientific and Technical Information of China (English)

    毕庆森

    2012-01-01

    Objective: To analyze the negative impact originated from the transfer of cost overrun risks to medical institutions from health-insurance funds. Method: Using literature search and site interviews. Result: It is illegal to pass on the overrun risk to medical institutions; value orientation is wrong; and it will have negative influences on medical institutions, patients and health insurance funds. Conclusion: To lower the risk, one should follow the strategy of structure reform, internal policy adjustment, or risk managing enhancement depending on overall budget; the government should take the responsibility of risk analysis and management.%目的:分析医保基金超支风险责任转嫁医疗机构的负面影响.方法:文献研究与现场访谈法.结果:将风险责任转嫁给医疗机构不符合法律规定;价值取向偏误;对医、患、保三方均有负面影响.结论:风险防范应通过体制改革及内部政策调整、加强风险因素管理等途径,依靠预算来实现;风险责任应由政府承担.

  13. IMPACTS !

    CERN Multimedia

    2008-01-01

    (Photo courtesy of Don Davis / NASA)The University of Geneva (UNIGE) and the Ecole Polytechnique Fédérale of Lausanne (EPFL) are organising the 4th series of public lectures on astronomy, on the theme of "Impacts". The schedule is as follows: Il y a 100 ans : une explosion dans la Tunguska – Dr. Frédéric COURBIN, EPFL Les impacts sur Terre – Prof. Didier Queloz, UNIGE La fin des dinosaures – Dr. Stéphane Paltani, UNIGE Wednesday 7 May 2008, from 7.00 p.m. to 9.00 p.m. Auditoire CO1, EPFL, Ecublens Thursday 08 May 2008, from 7.00 p.m. to 9.00 p.m. Auditoire Rouiller, Uni-Dufour, Genève All 3 lectures will be givent each evening! Admission free Information: 022 379 22 00

  14. Sentential Negation in English

    Science.gov (United States)

    Mowarin, Macaulay

    2009-01-01

    This paper undertakes a detailed analysis of sentential negation in the English language with Chomsky's Government-Binding theory of Transformational Grammar as theoretical model. It distinguishes between constituent and sentential negation in English. The essay identifies the exact position of Negation phrase in an English clause structure. It…

  15. The Negative Impacts of Whale-Watching

    OpenAIRE

    Parsons, E. C. M.

    2012-01-01

    Whale watching is an international industry worth more than US$2 billion globally and is currently the greatest economic activity reliant upon cetaceans. However, there is concern that whale watching is detrimental to the target species. Numerous studies have shown that cetaceans exhibit behavioral changes in response to whale-watching boat traffic. Some of these behavioral changes involve inhibiting biologically important behaviors such as feeding and resting. There is convincing evidence fo...

  16. Blunting the negative impact of healthcare reform.

    Science.gov (United States)

    Wallin, Venson; Parrott, Lynne; Simon, John

    2010-09-01

    To prepare for reform, organizations should take the following preventive measures: Create an integrated plan to evaluate the changes under health reform and implement actions for long-term financial success. Plan for lower Medicare payments by negotiating with commercial insurance carriers for contract renewals and implementing cost containment measures. Assess the effectiveness of the charge structure. Improve or establish new procedures to identify and report all charity care services provided. PMID:20830997

  17. We Media’s Negative Impact on Public Security’s Image and Countermeasures%自媒体对公安机关形象的消极影响及应对措施

    Institute of Scientific and Technical Information of China (English)

    韩磊

    2015-01-01

    With the rapid development of the “We Media” industry, the transmission of online information presents a new trend. The characteristics and the unique transmission mode of “We Media” makes lots of negative information of police work be produced and circulated, which has imposed a negative impact on public security’s image, weakened the police authorities, reduced the credibility of law enforcement and impeded the smooth conduct of public security work. Therefore, in order to handle the police image crisis timely and effectively, restore the damaged image and serve people better, public security organs should strengthen their own construction by enhancing cyberspace supervision, guiding the public opinion well and so on.%随着自媒体行业的快速发展,网络信息的传播呈现新的传播态势。自媒体自身的特点及其独特的传播方式使大量有关公安工作的负面信息得以滋生和流转,对公安机关的形象产生了消极影响,进而削弱了警察权威,降低了执法公信力,不利于公安工作的顺利开展。对此,公安机关应从抓好自身建设做起,加强网络监管,做好舆论引导,及时有效地处理好公安形象危机问题,重树公安机关良好形象,更好地为人民服务。

  18. 浅析媒体暴力对观众行为态度的正负面影响%Positive and Negative Impacts of Media Violence to Audience Behavior and Attitude

    Institute of Scientific and Technical Information of China (English)

    黄妍

    2011-01-01

    当今社会,媒体暴力对观众行为态度的影响已经俨然成为一个值得讨论的话题。国内外的许多专家学者也都对此做了无数的研究,并通过这些研究肯定了受众的行为态度是会受到媒体暴力所影响的。在本文中,我们基于任何事物都有其两面性的特点,客观的去认识媒体暴力的影响力,并阐述如何去避免其负面影响以及如何把负面影响降到最低,从而促进其积极面的发展。%Today's society,media violence on behavior and attitude of the audience already has become a topic worthy of discus-sion.Many domestic and foreign experts and scholars also have done numerous studies,and through these studies confirmed the audience's behavior and attitude will be affected by media violence.In this paper,we have everything on the characteristics of its two sides,the objective to understand the influence of media violence,and explains how to avoid its negative effects and to mini-mize the negative impact,so as to promote the positive aspects of development.

  19. Interpretations of Negative Probabilities

    OpenAIRE

    Burgin, Mark

    2010-01-01

    In this paper, we give a frequency interpretation of negative probability, as well as of extended probability, demonstrating that to a great extent, these new types of probabilities, behave as conventional probabilities. Extended probability comprises both conventional probability and negative probability. The frequency interpretation of negative probabilities gives supportive evidence to the axiomatic system built in (Burgin, 2009; arXiv:0912.4767) for extended probability as it is demonstra...

  20. Negative tandem mirror

    International Nuclear Information System (INIS)

    A tandem mirror configuration can be created by combining hot electron end cell plasmas with neutral beam pumping. A region of large negative potential formed in each end cell confines electrons in the central cell. The requirement of charge neutrality causes the central cell potential to become negative with respect to ground in order to confine ions as well as electrons. We discuss the method of producing and calculating the desired axial potential profile, and show the calculated axial potential profile and plasma parameters for a negative configuration of TMX-Upgrade

  1. A Prospective Randomized Trial to Study the Impact of Pretreatment FDG-PET for Cervical Cancer Patients With MRI-Detected Positive Pelvic but Negative Para-Aortic Lymphadenopathy

    International Nuclear Information System (INIS)

    Purpose: This prospective randomized study was undertaken to determine the possible impact of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) on extrapelvic metastasis detection, radiation field design, and survival outcome for cervical cancer patients with enlarged pelvic nodes on MRI image. Methods and Materials: Inclusion criteria were patients with newly diagnosed Stage I-IVA cervical cancer and with positive pelvic but negative para-aortic lymph nodes (PALN) as detected by magnetic resonance image and good performance status for concurrent chemoradiotherapy. Eligible patients were randomized to receive either pretreatment FDG-PET (study group) or not (control group). Whole pelvis was the standard irradiation field for the control group and those with no extrapelvic findings on PET. The radiation fields for the rest of the study group were extended to include the PALN region or were modified according to the extrapelvic PET finding. Results: From January 2002 to April 2006, 129 patients were included, and 66 of them were randomized to receive FDG-PET. PET detected seven extrapelvic metastases (11%, 6 PALN and 1 omental node), and four of them remained disease-free after treatment modification. For patients who underwent PET compared with those who did not, there were no differences in the 4-year rates of overall survival (79% vs. 85%, p = 0.65), disease-free survival (75% vs. 77%, p = 0.64), and distant metastasis-free survival (82% vs. 78%, p = 0.83). Conclusions: Pretreatment FDG-PET in conjunction with magnetic resonance imaging can improve the detection of extrapelvic metastasis, mainly PALN, and help select patients for extended-field radiotherapy. However, the addition of FDG-PET may not translate into survival benefit, even though PALN relapses are reduced.

  2. Logo and Negative Numbers.

    Science.gov (United States)

    Strawn, Candace A.

    1998-01-01

    Describes LOGO's turtle graphics capabilities based on a sixth-grade classroom's activities with negative numbers and Logo programming. A sidebar explains LOGO and offers suggestions to teachers for using LOGO effectively. (LRW)

  3. Isotropic Single Negative Metamaterials

    Directory of Open Access Journals (Sweden)

    P. Protiva

    2008-09-01

    Full Text Available This paper presents the application of simple, and therefore cheap, planar resonators for building 3D isotropic metamaterials. These resonators are: a broadside-coupled split ring resonator with a magnetic response providing negative permeability; an electric dipole terminated by a loop inductor together with a double H-shaped resonator with an electric response providing negative permittivity. Two kinds of 3D isotropic single negative metamaterials are reported. The first material consists of unit cells in the form of a cube bearing on its faces six equal planar resonators with tetrahedral symmetry. In the second material, the planar resonators boxed into spherical plastic shells and randomly distributed in a hosting material compose a real 3D volumetric metamaterial with an isotropic response. In both cases the metamaterial shows negative permittivity or permeability, according to the type of resonators that are used. The experiments prove the isotropic behavior of the cells and of the metamaterial specimens.

  4. 小学生同伴关系负面影响的对策研究%Study on the countermeasures of the negative impact of the pupils' peer relationships

    Institute of Scientific and Technical Information of China (English)

    王星妮

    2013-01-01

      The pupils' peer relationship is a very important interpersonal relationship in child's life, is the foundation of pupils to establish good interpersonal relationships. It will have far-reaching effects to children, to adapt to the school, the social life, and even the adult interpersonal relationship healthy development. The primary school is the starting point for the development of children's peer relationship, is the germination period of self-consciousness in children. Open and explicit children's psychological development, easy to understand children's real mental activities, is the gold period to become the cultivation of good peer relationship. Domestic and foreign researchers have done a lot of research, but few study on the influence of parents education idea for elementary school students peer relationship. So put forward some corresponding solutions on the negative impact on pupils' peer relationship, based on the analysis of the status quo at home and abroad and peer relationship, the paper put forward a review of the research on the peer relationship; analyzes the important problems for elementary school students peer relationship. Analysis of children's peer relationship and family education, and school education and social education, and put forward the countermeasures to the negative influence.%  小学生的同伴关系是儿童生活中的一种非常重要人际关系,是小学生建立良好的人际关系的基础。它对儿童,适应学校、社会生活,乃至成人后的人际关系的健康成长都会产生深远的影响。小学阶段是儿童同伴关系发展的起点,是儿童自我意识的萌发时期。儿童心理发展的开放性和外显性,便于了解儿童真实的心理活动,是成为培养良好同伴关系黄金期。国内外的研究者们对此做了大量的探索,但父母教育观念对小学生同伴关系的影响的研究却很少。所以对小学生同伴关系的负面影响提出

  5. Carbon-negative biofuels

    International Nuclear Information System (INIS)

    Current Kyoto-based approaches to reducing the earth's greenhouse gas problem involve looking for ways to reduce emissions. But these are palliative at best, and at worst will allow the problem to get out of hand. It is only through sequestration of atmospheric carbon that the problem can be solved. Carbon-negative biofuels represent the first potentially huge assault on the problem, in ways that are already technically feasible and practicable. The key to carbon negativity is to see it not as technically determined but as an issue of strategic choice, whereby farmers and fuel producers can decide how much carbon to return to the soil. Biochar amendment to the soil not only sequesters carbon but also enhances the fertility and vitality of the soil. The time is approaching when biofuels will be carbon negative by definition, and, as such, they will sweep away existing debates over their contribution to the solution of global warming. (author)

  6. Tunneling with negative tension

    CERN Document Server

    Marvel, Kate

    2008-01-01

    We describe a new family of thin-wall instantons, with negative tension bubble walls, that mediate tunneling between Minkowski or de Sitter vacua. Some of these instantons can have exponentially enhanced tunneling rates, and would dominate the Euclidean path integral, representing a severe non-perturbative instability in any theory which supports them. We give two constructions of these instantons in theories which are perturbatively stable, but violate the null energy condition. One construction uses a scalar field theory with higher-derivative kinetic term, and is similar to the Coleman-de Luccia positive tension instanton. The other construction employs a negative-tension boundary arising from Z_2 orbifolding: it resembles a "bubble of nothing" which nucleates and grows, consuming the surrounding de Sitter or Minkowski spacetime. We explain how the spectral flow for fluctutations about the thin-wall tunneling solutions automatically protects causality, for both positive and negative tension instantons. We ...

  7. Negative Probabilities and Contextuality

    CERN Document Server

    de Barros, J Acacio; Oas, Gary

    2015-01-01

    There has been a growing interest, both in physics and psychology, in understanding contextuality in experimentally observed quantities. Different approaches have been proposed to deal with contextual systems, and a promising one is contextuality-by-default, put forth by Dzhafarov and Kujala. The goal of this paper is to present a tutorial on a different approach: negative probabilities. We do so by presenting the overall theory of negative probabilities in a way that is consistent with contextuality-by-default and by examining with this theory some simple examples where contextuality appears, both in physics and psychology.

  8. Depressionens negative spiral

    DEFF Research Database (Denmark)

    Munk, Karen

    2006-01-01

    Artiklen formidler resultater fra en longitudinel undersøgelse af det selvforstærkende, negative samspil imellem udvikling og vedligeholdelse af alderdomsdepression via primære miljøbelastninger og via  den deprimerede ældre som belastning for miljøet, som i sin tur "svarer negativt" på lidelsen ...

  9. Negative magnetoresistivity in holography

    CERN Document Server

    Sun, Ya-Wen

    2016-01-01

    Negative magnetoresistivity is a special magnetotransport property associated with chiral anomaly in four dimensional chiral anomalous systems, which refers to the transport behavior that the DC longitudinal magnetoresistivity decreases with increasing magnetic field. We calculate the longitudinal magnetoconductivity in the presence of backreactions of the magnetic field to gravity in holographic zero charge and axial charge density systems with and without axial charge dissipation. In the absence of axial charge dissipation, we find that the quantum critical conductivity grows with increasing magnetic field when the backreaction strength is larger than a critical value, in contrast to the monotonically decreasing behavior of quantum critical conductivity in the probe limit. With axial charge dissipation, we find the negative magnetoresistivity behavior. The DC longitudinal magnetoconductivity scales as $B$ in the large magnetic field limit, which deviates from the exact $B^2$ scaling of the probe limit resul...

  10. Think (Gram) negative!

    Science.gov (United States)

    2010-01-01

    The increasing prevalence of multiresistant Gram-negative bacteria of the Enterobacteriaceae family in Europe is a worrisome phenomenon. Extended spectrum betalactamase-producing Escherichia coli strains are widespread in the community and are frequently imported into the hospital. Of even more concern is the spread of carbapenem-resistant strains of Klebsiella spp. from regions where they are already endemic. Antibiotic use is a main driver of antibiotic resistance, which again increases broad spectrum antibiotic use, resulting in a vicious circle that is difficult to interrupt. The present commentary highlights important findings of a surveillance study of antimicrobial use and resistance in German ICUs over 8 years with a focus on Gram-negative resistance. PMID:20587087

  11. Negative und positive Integration

    OpenAIRE

    Scharpf, F.

    2008-01-01

    Der Beitrag beschäftigt sich mit den Wirkungen der europäischen Integration auf das Grundproblem traditioneller wie moderner Politischer Ökonomie: Die Arbeitsteilung zwischen Staat und Markt. Im Mittelpunkt steht die "negative Integration" und ihr einzigartiger Erfolg bei der Beseitigung der in den Nachkriegsjahrzehnten gewonnenen Kontrolle des Nationalstaates über seine ökonomischen Außengrenzen. Durch die "Konstitutionalisierung" des Wettbewerbsrechts haben die Europäische Kommission ...

  12. Primitive Virtual Negative Charge

    OpenAIRE

    Kim, Kiyoung

    2008-01-01

    Physical fields, such as gravity and electromagnetic field, are interpreted as results from rearrangement of vacuum particles to get the equilibrium of net charge density and net mass density in 4-dimensional complex space. Then, both fields should interact to each other in that physical interaction is considered as a field-to-field interaction. Hence, Mass-Charge interaction is introduced with primitive-virtual negative charge defined for the mass. With the concept of Mass-Charge interaction...

  13. Negative agency costs

    OpenAIRE

    Jacques Thépot

    2009-01-01

    Managerial opportunism is commonly considered as destructive for the parties involved in an agency relationship. Using a close formulation to Jensen and Meckling’s equity model, we consider an agency relationship between a manager and an investor. The latter is assumed to benefit from a market power through external funding opportunities. For high values of the prevailing rate of interest, we prove that the agency costs can be negative, either when the manager or the investor acts as the lead...

  14. Negative refractive index metamaterials

    Directory of Open Access Journals (Sweden)

    Willie J. Padilla

    2006-07-01

    Full Text Available Engineered materials composed of designed inclusions can exhibit exotic and unique electromagnetic properties not inherent in the individual constituent components. These artificially structured composites, known as metamaterials, have the potential to fill critical voids in the electromagnetic spectrum where material response is limited and enable the construction of novel devices. Recently, metamaterials that display negative refractive index – a property not found in any known naturally occurring material – have drawn significant scientific interest, underscoring the remarkable potential of metamaterials to facilitate new developments in electromagnetism.

  15. Negatively buoyant starting jets

    OpenAIRE

    Marugán-Cruz, C.; Rodríguez-Rodríguez, Javier; Martínez-Bazán, C.

    2009-01-01

    The initial development of negatively buoyant jets has been investigated experimentally and numerically, focusing on the role played by gravity in the evolution of the leading vortex ring. Under the experimental conditions considered in this work, the densimetric Froude number, Fr= ρjU²j/[(ρ₀ − ρj) gD] , which represents the ratio between the jet momentum and the buoyancy forces, emerges as the most relevant parameter characterizing the dynamics of the flow. Two different flow regimes h...

  16. Negative Average Preference Utilitarianism

    Directory of Open Access Journals (Sweden)

    Roger Chao

    2012-03-01

    Full Text Available For many philosophers working in the area of Population Ethics, it seems that either they have to confront the Repugnant Conclusion (where they are forced to the conclusion of creating massive amounts of lives barely worth living, or they have to confront the Non-Identity Problem (where no one is seemingly harmed as their existence is dependent on the “harmful” event that took place. To them it seems there is no escape, they either have to face one problem or the other. However, there is a way around this, allowing us to escape the Repugnant Conclusion, by using what I will call Negative Average Preference Utilitarianism (NAPU – which though similar to anti-frustrationism, has some important differences in practice. Current “positive” forms of utilitarianism have struggled to deal with the Repugnant Conclusion, as their theory actually entails this conclusion; however, it seems that a form of Negative Average Preference Utilitarianism (NAPU easily escapes this dilemma (it never even arises within it.

  17. Negative leave balances

    CERN Multimedia

    Human Resources Department

    2005-01-01

    Members of the personnel entitled to annual leave and, where appropriate, saved leave and/or compensatory leave are requested to take note of the new arrangements described below, which were recommended by the Standing Concertation Committee (SCC) at its meeting on 1Â September 2005 and subsequently approved by the Director-General. The changes do not apply to members of the personnel participating in the Progressive Retirement Programme (PRP) or the Part-time Work as a pre-retirement measure, for whom the specific provisions communicated at the time of joining will continue to apply. Â Negative balances in annual leave, saved leave and/or compensatory leave accounts at the end of the leave year (30th September) and on the date on which bonuses are credited to the saved leave account (31st December): Where members of the personnel have a leave account with a negative balance on 30Â September and/or 31Â December, leave will automatically be transferred from one account to another on the relevant dates i...

  18. Negative leave balances

    CERN Multimedia

    Human Resources Department

    2005-01-01

    Members of the personnel entitled to annual leave and, where appropriate, saved leave and/or compensatory leave are requested to take note of the new arrangements described below, which were recommended by the Standing Concertation Committee (SCC) at its meeting on 1 September 2005 and subsequently approved by the Director-General. The changes do not apply to members of the personnel participating in the Progressive Retirement Programme (PRP) or the Part-time Work as a pre-retirement measure, for whom the specific provisions communicated at the time of joining will continue to apply.  Negative balances in annual leave, saved leave and/or compensatory leave accounts at the end of the leave year (30th September) and on the date on which bonuses are credited to the saved leave account (31st December): Where members of the personnel have a leave account with a negative balance on 30 September and/or 31 December, leave will automatically be transferred from one account to another on the relevant dates in or...

  19. Polarized negative ions

    Energy Technology Data Exchange (ETDEWEB)

    Haeberli, W.

    1981-04-01

    This paper presents a survey of methods, commonly in use or under development, to produce beams of polarized negative ions for injection into accelerators. A short summary recalls how the hyperfine interaction is used to obtain nuclear polarization in beams of atoms. Atomic-beam sources for light ions are discussed. If the best presently known techniques are incorporated in all stages of the source, polarized H/sup -/ and D/sup -/ beams in excess of 10 ..mu..A can probably be achieved. Production of polarized ions from fast (keV) beams of polarized atoms is treated separately for atoms in the H(25) excited state (Lamb-Shift source) and atoms in the H(1S) ground state. The negative ion beam from Lamb-Shift sources has reached a plateau just above 1 ..mu..A, but this beam current is adequate for many applications and the somewhat lower beam current is compensated by other desirable characteristics. Sources using fast polarized ground state atoms are in a stage of intense development. The next sections summarize production of polarized heavy ions by the atomic beam method, which is well established, and by optical pumping, which has recently been demonstrated to yield very large nuclear polarization. A short discussion of proposed ion sources for polarized /sup 3/He/sup -/ ions is followed by some concluding remarks.

  20. Polarized negative ions

    International Nuclear Information System (INIS)

    This paper presents a survey of methods, commonly in use or under development, to produce beams of polarized negative ions for injection into accelerators. A short summary recalls how the hyperfine interaction is used to obtain nuclear polarization in beams of atoms. Atomic-beam sources for light ions are discussed. If the best presently known techniques are incorporated in all stages of the source, polarized H- and D- beams in excess of 10 μA can probably be achieved. Production of polarized ions from fast (keV) beams of polarized atoms is treated separately for atoms in the H(25) excited state (Lamb-Shift source) and atoms in the H(1S) ground state. The negative ion beam from Lamb-Shift sources has reached a plateau just above 1 μA, but this beam current is adequate for many applications and the somewhat lower beam current is compensated by other desirable characteristics. Sources using fast polarized ground state atoms are in a stage of intense development. The next sections summarize production of polarized heavy ions by the atomic beam method, which is well established, and by optical pumping, which has recently been demonstrated to yield very large nuclear polarization. A short discussion of proposed ion sources for polarized 3He- ions is followed by some concluding remarks

  1. Moral expressivism and sentential negation

    OpenAIRE

    Sinclair, Neil

    2011-01-01

    This paper advances three necessary conditions on a successful account of sentential negation. First, the ability to explain the constancy of sentential meaning across negated and unnegated contexts (the Fregean Condition). Second, the ability to explain why sentences and their negations are inconsistent, and inconsistent in virtue of the meaning of negation (the Semantic Condition). Third, the ability of the account to generalize regardless of the topic of the negated sentence (the Generalit...

  2. Primitive Virtual Negative Charge

    CERN Document Server

    Kim, Kiyoung

    2008-01-01

    Physical fields, such as gravity and electromagnetic field, are interpreted as results from rearrangement of vacuum particles to get the equilibrium of net charge density and net mass density in 4-dimensional complex space. Then, both fields should interact to each other in that physical interaction is considered as a field-to-field interaction. Hence, Mass-Charge interaction is introduced with primitive-virtual negative charge defined for the mass. With the concept of Mass-Charge interaction electric equilibrium of the earth is discussed, especially about the electric field and magnetic field of the earth. For unsettled phenomena related with the earth's gravity, such as antigravity phenomenon, gravity anomalies during the solar eclipses, the connection between geomagnetic storms and earthquakes, etc., possible explanations are discussed.

  3. Negative Entropy of Life

    Science.gov (United States)

    Goradia, Shantilal

    2015-10-01

    We modify Newtonian gravity to probabilistic quantum mechanical gravity to derive strong coupling. If this approach is valid, we should be able to extend it to the physical body (life) as follows. Using Boltzmann equation, we get the entropy of the universe (137) as if its reciprocal, the fine structure constant (ALPHA), is the hidden candidate representing the negative entropy of the universe which is indicative of the binary information as its basis (http://www.arXiv.org/pdf/physics0210040v5). Since ALPHA relates to cosmology, it must relate to molecular biology too, with the binary system as the fundamental source of information for the nucleotides of the DNA as implicit in the book by the author: ``Quantum Consciousness - The Road to Reality.'' We debate claims of anthropic principle based on the negligible variation of ALPHA and throw light on thermodynamics. We question constancy of G in multiple ways.

  4. Positive Effects of Negative Publicity: When Negative Reviews Increase Sales

    OpenAIRE

    Jonah Berger; Alan T. Sorensen; Scott J. Rasmussen

    2010-01-01

    Can negative information about a product increase sales, and if so, when? Although popular wisdom suggests that "any publicity is good publicity," prior research has demonstrated only downsides to negative press. Negative reviews or word of mouth, for example, have been found to hurt product evaluation and sales. Using a combination of econometric analysis and experimental methods, we unify these perspectives to delineate contexts under which negative publicity about a product will have posit...

  5. The Impact of Organization-Based Self-Esteem on Employees’ Work Alienation-The Role of Negative Emotion and Traditionality%组织自尊对员工工作疏离感影响的实证研究--消极情绪和传统性的作用

    Institute of Scientific and Technical Information of China (English)

    余璇; 陈维政

    2016-01-01

    依据自我一致理论和情感事件理论,文章探讨了组织自尊对员工工作疏离感及其各维度的影响,并检验了消极情绪的中介效应和传统性的调节效应。对448个员工样本的调查问卷进行统计分析,结果显示:(1)组织自尊对员工工作疏离感及其各维度(工作任务疏离感、工作人际疏离感和工作环境疏离感)、消极情绪有显著的负向影响;(2)消极情绪在组织自尊对员工工作疏离感及其各维度的影响中具有部分中介效应;(3)传统性在消极情绪对员工工作疏离感、工作任务疏离感、工作人际疏离感的影响中具有显著调节效应,对工作环境疏离感的影响中不具有显著调节效应。%Based on self‐consistent theory and affective event theory ,the study explored the impact of organiza‐tion‐based self‐esteem on employees’ work alienation and its various dimensions ,and examined the mediating effect of negative emotion and the moderating effect of traditionality .The results of statistical analysis from 448 employees shows that (1) Organization‐based self‐esteem has a significant negative impact on work alienation and its various dimensions(job alienation ,interpersonal alienation and environment alienation) ,and also on negative emotion;(2)Negative emotion plays a partial mediating effect in the impact of organization‐based self‐esteem on work alienation and its various dimensions ,and (3)traditionality plays a significant moderating effect in the impact of organization‐based self‐esteem on negative emotion on work alienation ,job alienation and inter‐personal alienation ,but not on environment alienation .

  6. Negative Expertise: Comparing Differently Tenured Elder Care Nurses' Negative Knowledge

    Science.gov (United States)

    Gartmeier, Martin; Lehtinen, Erno; Gruber, Hans; Heid, Helmut

    2011-01-01

    Negative expertise is conceptualised as the professional's ability to avoid errors during practice due to certain cognitive agencies. In this study, negative knowledge (i.e. knowledge about what is wrong in a certain context and situation) is conceptualised as one such agency. This study compares and investigates the negative knowledge of elder…

  7. Microdosimetry of negative pions

    International Nuclear Information System (INIS)

    The radiation quality of negative and positive pions of initial momentum 168MeV/c has been determined at eight different depths in a liquid phantom. The measurements were made with a 2.5cm diameter spherical proportional counter with Shonka A-150 neutron tissue equivalent plastic walls. The gas pressure in the sensitive volume was chosen to stimulate a diameter of 2μm in unit density material. Dose distributions as a function of lineal energy change slowly in the entrance and plateau regions with a dose mean lineal energy of 6-8keV/μm. Less than 3% of the dose is delivered in excess of 50keV/μm in this region. In the Bragg peak region the distributions change rapidly as a function of depth with the dose mean lineal energy increasing to 38keV/μm at the peak and to 57keV/μm just beyond the peak. On the basis of these microdosimetric data predictions of RBE and OER have been made with the use of both the theory of dual radiation action and also the delta ray theory of cell survival. The former has been used to predict biological response at low doses and the latter at high doses. A comparison is made between the two theories at intermediate doses. The results of these calculations are not inconsistant with recent biological data

  8. Coagulase-negative staphylococci.

    Science.gov (United States)

    Becker, Karsten; Heilmann, Christine; Peters, Georg

    2014-10-01

    The definition of the heterogeneous group of coagulase-negative staphylococci (CoNS) is still based on diagnostic procedures that fulfill the clinical need to differentiate between Staphylococcus aureus and those staphylococci classified historically as being less or nonpathogenic. Due to patient- and procedure-related changes, CoNS now represent one of the major nosocomial pathogens, with S. epidermidis and S. haemolyticus being the most significant species. They account substantially for foreign body-related infections and infections in preterm newborns. While S. saprophyticus has been associated with acute urethritis, S. lugdunensis has a unique status, in some aspects resembling S. aureus in causing infectious endocarditis. In addition to CoNS found as food-associated saprophytes, many other CoNS species colonize the skin and mucous membranes of humans and animals and are less frequently involved in clinically manifested infections. This blurred gradation in terms of pathogenicity is reflected by species- and strain-specific virulence factors and the development of different host-defending strategies. Clearly, CoNS possess fewer virulence properties than S. aureus, with a respectively different disease spectrum. In this regard, host susceptibility is much more important. Therapeutically, CoNS are challenging due to the large proportion of methicillin-resistant strains and increasing numbers of isolates with less susceptibility to glycopeptides. PMID:25278577

  9. Negative results: negative perceptions limit their potential for increasing reproducibility.

    Science.gov (United States)

    Teixeira da Silva, Jaime A

    2015-01-01

    Negative results are an important building block in the development of scientific thought, primarily because most likely the vast majority of data is negative, i.e., there is not a favorable outcome. Only very limited data is positive, and that is what tends to get published, albeit alongside a sub-set of negative results to emphasize the positive nature of the positive results. Yet, not all negative results get published. Part of the problem lies with a traditional mind-set and rigid publishing frame-work that tends to view negative results in a negative light, or that only tends to reward scientists primarily for presenting positive findings. This opinion piece indicates that in addition to a deficient mind-set, there are also severe limitations in the availability of publishing channels where negative results could get published. PMID:26149259

  10. Negative chemical ionization mass spectrometry

    International Nuclear Information System (INIS)

    This thesis describes some aspects of Negative Chemical Ionization (NCI) mass spectrometry. The reasons for the growing interest in NCI are: (i) to extend the basic knowledge of negative ions and their reactions in the gas phase; (ii) to investigate whether or not this knowledge of negative ions can be used successfully to elucidate the structure of molecules by mass spectrometry. (Auth.)

  11. 负性生活事件对新疆公务员生存质量的影响%The impact of negative life events on quality of life of civil servants in Xinjiang

    Institute of Scientific and Technical Information of China (English)

    陈洁; 周增桓; 屈荣杰

    2012-01-01

    Objective To explore the relationship between negative life events and the quality of life of civil servants in Xinjiang. Methods A total of 2695 civil servants in Xinjiang were investigated with SF-36 scale and self-designed negative life events questionnaire. Results 18.33 % of the investigated civil servants had a low quality of life with a score less than 60, and the total average quality-of-life score was 73.16 ± 13.40. The quality-of-life score of civil servants in Xinjiang encountering no , few and many negative events was 76.00 ± 12.71, 71.03 ± 13.23 and 58.47 ± 11.49, respectively, with statistical difference (F = 104.215, P = 0.000). There was a lower negative correlation between the negative life event and the quality-of-life score (r = -0.299, P = 0.000). The multivariate analysis revealed that romance (OR = 2.318) , divorce (OR = 2.767) , family financial problems(OR=2.086) , loss of valuables (OR = 2.447) , housing shortage (OR = 1.370) , satisfaction with job (OR = 1.946), tension between colleagues (OR = 2.126), disharmony with neighbors (OR = 2.447) and emergencies (OR = 2.889) were associated with quality of life. Conclusion Low quality of life of civil servants in Xinjiang was associated with romance, divorce, family financial problems, loss of valuables, housing shortage, satisfaction with job, tension between colleagues and disharmony with neighbors.%目的:探讨负性生活事件与公务员生存质量的关系.方法:应用SF-36量表和自制的负性生活事件量表对2695名新疆公务员进行调查.结果:新疆公务员生存质量总分低于60分占18.33%,总均分为(73.16 ± 13.40)分.无、少和多负性事件组的新疆公务员生存质量总分分别为(76.00 ± 12.71)、(71.03 ± 13.23)和 (58.47 ± 11.49)分,差异有统计学意义(F = 104.215,P = 0.000).负性生活事件得分与生存质量得分呈低度负相关,差异有统计学意义(r = -0.299,P = 0.000).多因素分析显示,失恋(OR = 2.318)

  12. Factors impacting knowledge and use of long acting and permanent contraceptive methods by postpartum HIV positive and negative women in Cape Town, South Africa: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Credé Sarah

    2012-03-01

    Full Text Available Abstract Background The prevention of unintended pregnancies among HIV positive women is a neglected strategy in the fight against HIV/AIDS. Women who want to avoid unintended pregnancies can do this by using a modern contraceptive method. Contraceptive choice, in particular the use of long acting and permanent methods (LAPMs, is poorly understood among HIV-positive women. This study aimed to compare factors that influence women's choice in contraception and women's knowledge and attitudes towards the IUD and female sterilization by HIV-status in a high HIV prevalence setting, Cape Town, South Africa. Methods A quantitative cross-sectional survey was conducted using an interviewer-administered questionnaire amongst 265 HIV positive and 273 HIV-negative postpartum women in Cape Town. Contraceptive use, reproductive history and the future fertility intentions of postpartum women were compared using chi-squared tests, Wilcoxon rank-sum and Fisher's exact tests where appropriate. Women's knowledge and attitudes towards long acting and permanent methods as well as factors that influence women's choice in contraception were examined. Results The majority of women reported that their most recent pregnancy was unplanned (61.6% HIV positive and 63.2% HIV negative. Current use of contraception was high with no difference by HIV status (89.8% HIV positive and 89% HIV negative. Most women were using short acting methods, primarily the 3-monthly injectable (Depo Provera. Method convenience and health care provider recommendations were found to most commonly influence method choice. A small percentage of women (6.44% were using long acting and permanent methods, all of whom were using sterilization; however, it was found that poor knowledge regarding LAPMs is likely to be contributing to the poor uptake of these methods. Conclusions Improving contraceptive counselling to include LAPM and strengthening services for these methods are warranted in this setting

  13. Impact of experimental endogenous gram-negative peritonitis on the pancreas of the rat as evaluated by cationic trypsin-like immunoreactivity in peritoneal fluid and serum and by electron microscopy of pancreatic tissue

    International Nuclear Information System (INIS)

    Endogenous gram-negative peritonitis leading to septic shock was induced in rats by a defined perforation of the coecum. Cationic trypsin-like immunoreactivity (CTLI) was measured in peritoneal fluid and serum by a radioimmunoassay method. 5, 10 and 15 h after the coecal perforation, CTLI in peritoneal fluid was significantly higher than before the coecal perforation and also higher than in the corresponding control rats. Moreover, CTLI in serum was under the same conditions significantly higher 10 and 15 h after the induction of peritonitis. Gel chromatography of peritoneal fluid and serum during peritonitis showed free CTLI and CTLI bound to both alpha-1-antitrypsin and alpha-2-macroglobulin, wheras only free CTLI could be detected in serum from control rats. These findings were accompanied by local ultrastructural changes in the acinar cells as evaluated by electron microscopy. The pathophysiologic implications of the findings are discussed

  14. The discussion about the negative impact of television advertising on children's moral education%论电视广告对儿童道德教育的负面影响

    Institute of Scientific and Technical Information of China (English)

    冯石岗; 王立杰; 高怡钧

    2014-01-01

    TV advertising is to promote goods or services, promote the enterprise image, and establish the consumption idea, in order to get consumer recognition, it can use a variety of media exerts a subtle influence on the children's thinking and understanding and value judgment. Television advertising is a double-edged sword, positive advertising motivating, negative ads mislead people, also can bring the enemies we make, can not only promote beauty and goodness and truth lives on for its negative effects on children's moral education are various:will have far-reaching effects on children's growth, the need to attract the attention of the social related groups.%电视广告是为了宣传商品或服务、宣传企业形象和树立消费观念,为了得到消费者的认可,它可以借助多种媒介潜移默化地影响着儿童的思想认识和价值判断。电视广告是一把双刃剑,正面的广告激励人、负面的广告误导人,既可以宣扬真善美,也可以带来假丑恶,其对儿童道德教育的负面影响是多方面的:会对儿童的成长产生深远的不良影响,需要引起社会相关群体的注意。

  15. Acoustic metamaterial with negative modulus and a double negative structure

    OpenAIRE

    Sharma, Bhisham; Sun, Chin-teh

    2015-01-01

    An acoustic negative bulk modulus metamaterial based on the concept of expansion chambers is proposed. It is shown that addition of a neck region to an ordinary expansion chamber improves its transmission loss characteristics at low frequencies and the resulting structure displays a negative bulk modulus behavior. Additionally, membrane based metamaterials are analyzed. Using FEM, the negative density behavior of a membrane carrying a center mass and of a tensioned membrane array is analyzed ...

  16. Negative snakes in JET: evidence for negative shear

    Energy Technology Data Exchange (ETDEWEB)

    Gill, R.D.; Alper, B.; Edwards, A.W. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking; Pearson, D. [Reading Univ. (United Kingdom)

    1994-07-01

    The signature of the negative snakes from the soft X-ray cameras is very similar to the more usual snakes except that the localised region of the snake has, compared with its surroundings, decreased rather than increased emission. Circumstances where negative snakes have been seen are reviewed. The negative snake appears as a region of increased resistance and of increased impurity density. The relationship between the shear and the current perturbation is shown, and it seem probable that the magnetic shear is reversed at the point of the negative snake, i.e. that q is decreasing with radius. 6 refs., 6 figs.

  17. Acoustic metamaterial with negative modulus and a double negative structure

    CERN Document Server

    Sharma, Bhisham

    2015-01-01

    An acoustic negative bulk modulus metamaterial based on the concept of expansion chambers is proposed. It is shown that addition of a neck region to an ordinary expansion chamber improves its transmission loss characteristics at low frequencies and the resulting structure displays a negative bulk modulus behavior. Additionally, membrane based metamaterials are analyzed. Using FEM, the negative density behavior of a membrane carrying a center mass and of a tensioned membrane array is analyzed and the inherent similarity of the two designs is discussed. Further, the modified expansion chamber is combined with an array of stretched membranes and the resulting structure is analyzed for double negative behavior.

  18. Group counseling for nursing students before negative psychological impact on employment%团体心理咨询对实习护生就业前负性心理的影响

    Institute of Scientific and Technical Information of China (English)

    廖红珍; 卢志坚; 黄萍; 杨素芬; 吴国友; 叶颜凤; 张月嫦

    2015-01-01

    目的:探讨团体心理咨询对实习护生就业前负性心理的影响。方法将120名实习护生随机分为观察组和对照组各60名 ,观察组进院实习后应用团体心理咨询的方法进行训练,对照组不进行团体心理咨询训练。两组均采用抑郁自评量表(SDS)、焦虑自评量表(SAS)和自信心量表(SES)对实习护生在心理咨询前与团体心理咨询训练结束后各测评1次,并进行对比分析。结果观察组实习护生进行团体心理咨询后 SDS 、SAS 测评分值明显低于对照组,出现负性心理(焦虑、抑郁)的例数较对照组明显减少,差异有统计学意义( P <0.05);观察组实习护生自信心测评得分较对照组明显提高,差异有统计学意义( P <0.05)。结论团体心理咨询能有效减轻实习护生就业前的负性心理(焦虑、抑郁),提高自信心,同时也提高实习护生对未来就业的信心。%Objective To investigate the group counseling on employment in nursing students before negative psy ‐chological effects . Methods Selected of 120 name internship nursing born random is divided into group and con‐trol group ,each 60 name ,group into homes internship hou application groups psychological advisory of method for training ,control group not for groups psychological advisory training ;two group are used depression since assess‐ment volume table (SDS ) ,and anxiety since assessment volume table (SAS ) and self‐confidence volume table (SES) ,on internship nursing born in for groups psychological advisory qian and groups psychological advisory training ended hou each evaluation once ,then for compared analysis . Results Study group after group counseling nursing students SDS and SAS test scores significantly lower than control group ,appeared negative psychological (SDS and SAS) significantly reduced the number of cases compared with the control group ,there was a statistically

  19. Negative hydrogen ion production mechanisms

    International Nuclear Information System (INIS)

    Negative hydrogen/deuterium ions can be formed by processes occurring in the plasma volume and on surfaces facing the plasma. The principal mechanisms leading to the formation of these negative ions are dissociative electron attachment to ro-vibrationally excited hydrogen/deuterium molecules when the reaction takes place in the plasma volume, and the direct electron transfer from the low work function metal surface to the hydrogen/deuterium atoms when formation occurs on the surface. The existing theoretical models and reported experimental results on these two mechanisms are summarized. Performance of the negative hydrogen/deuterium ion sources that emerged from studies of these mechanisms is reviewed. Contemporary negative ion sources do not have negative ion production electrodes of original surface type sources but are operated with caesium with their structures nearly identical to volume production type sources. Reasons for enhanced negative ion current due to caesium addition to these sources are discussed

  20. Wages, Amenities and Negative Attitudes

    OpenAIRE

    Waisman, Gisela; Larsen, Birthe

    2012-01-01

    We exploit the regional variation in negative attitudes towards immigrants to Sweden in order to analyse the consequences of the attitudes on immigrants welfare. We find that attitudes towards immigrants are of importance: they both affect their labour market outcomes and their quality of life. We interpret the negative effect on wages as evidence of labour market discrimination. We estimate the welfare effects of negative attitudes, through their wage and local amenities, for immigrants with...

  1. Economic impacts of climate change

    OpenAIRE

    Tol, Richard S.J.

    2015-01-01

    Climate change will probably have a limited impact on the economy and human welfare in the 21st century. The initial impacts of climate change may well be positive. In the long run, the negative impacts dominate the positive ones. Negative impacts will be substantially greater in poorer, hotter, and lower-lying countries. Poverty reduction complements greenhouse gas emissions reduction as a means to reduce climate change impacts. Climate change may affect the growth rate of the economy and ma...

  2. An electromagnetic trinity from "negative permittivity" and "negative permeability"

    CERN Document Server

    Lakhtakia, A

    2001-01-01

    An electromagnetic trinity comprising vacuum, anti--vacuum, and nihility is postulated -- after making use of materials with "negative permittivity" and "negative permeability" -- to illuminate the structure of electromagnetic theory, at least insofar as the relationship of phase velocity with Poynting vector is concerned.

  3. Intrinsic Negative Mass from Nonlinearity

    Science.gov (United States)

    Di Mei, F.; Caramazza, P.; Pierangeli, D.; Di Domenico, G.; Ilan, H.; Agranat, A. J.; Di Porto, P.; DelRe, E.

    2016-04-01

    We propose and provide experimental evidence of a mechanism able to support negative intrinsic effective mass. The idea is to use a shape-sensitive nonlinearity to change the sign of the mass in the leading linear propagation equation. Intrinsic negative-mass dynamics is reported for light beams in a ferroelectric crystal substrate, where the diffusive photorefractive nonlinearity leads to a negative-mass Schrödinger equation. The signature of inverted dynamics is the observation of beams repelled from strongly guiding integrated waveguides irrespective of wavelength and intensity and suggests shape-sensitive nonlinearity as a basic mechanism leading to intrinsic negative mass.

  4. Negative cooperativity in regulatory enzymes.

    Science.gov (United States)

    Levitzki, A; Koshland, D E

    1969-04-01

    Negative cooperativity has been observed in CTP synthetase, an allosteric enzyme which contains a regulatory site. Thus, the same enzyme exhibits negative cooperativity for GTP (an effector) and glutamine (a substrate) and positive cooperativity for ATP and UTP (both substrates). In the process of the delineation of these phenomena, diagnostic procedures for negative cooperativity were developed. Application of these procedures to other enzymes indicates that negative cooperativity is a characteristic of many of them. These findings add strong support for the sequential model of subunit interactions which postulates that ligand-induced conformational changes are responsible for regulatory and cooperative phenomena in enzymes. PMID:5256410

  5. Income, Amenities and Negative Attitudes

    DEFF Research Database (Denmark)

    Waisman, Gisela; Larsen, Birthe

    2016-01-01

    We exploit the regional variation in negative attitudes towards immigrants to Sweden in order to analyse the consequences of negative attitudes on refugees’ utility from labour income and amenities. We find that attitudes towards immigrants are important: while they affect mainly the refugees...

  6. The case for negative senescence

    DEFF Research Database (Denmark)

    Vaupel, James W; Baudisch, Annette; Dölling, Martin;

    2004-01-01

    Negative senescence is characterized by a decline in mortality with age after reproductive maturity, generally accompanied by an increase in fecundity. Hamilton (1966) ruled out negative senescence: we adumbrate the deficiencies of his model. We review empirical studies of various plants and some...

  7. Negative phototropism of rice root

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@It is often believed that the stem of higher plants has characteristics of positive phototropism, and the root shows no phototropism or no sensitivity to light though the root of Arabdopsis was reported possessing characteristics of negative phototropism. In this study, a distinct negative phototropism of the root system of rice seedlings was observed.

  8. Assessing climate impacts

    OpenAIRE

    Wohl, Ellen E.; Roger S. Pulwarty; Zhang, Jian Yun

    2000-01-01

    Assessing climate impacts involves identifying sources and characteristics of climate variability, and mitigating potential negative impacts of that variability. Associated research focuses on climate driving mechanisms, biosphere–hydrosphere responses and mediation, and human responses. Examples of climate impacts come from 1998 flooding in the Yangtze River Basin and hurricanes in the Caribbean and Central America. Although we have limited understanding of the fu...

  9. Analysis of Negative Correlation Learning

    Institute of Scientific and Technical Information of China (English)

    Liu Yong; Zou Xiu-fen

    2003-01-01

    This paper describes negative correlation learning for designing neural network ensembles. Negative correlation learning has been firstly analysed in terms of minimising mutual information on a regression task. By ninimising the mutual information between variables extracted by two neural networks, they are forced to convey different information about some features of their input. Based on the decision boundaries and correct response sets, negative correlation learning has been further studied on two pattern classification problems. The purpose of examining the decision boundaries and the correct response sets is not only to illustrate the learning behavior of negative correlation learning, but also to cast light on how to design more effective neural network ensembles. The experimental results showed the decision boundary of the trained neural network ensemble by negative correlation learning is almost as good as the optimum decision boundary.

  10. Negative refraction by photonic nanostructures

    Science.gov (United States)

    Wu, Qi

    Artificially engineered optical materials composed of nano-structures have unique optical properties which are not available with naturally occurring materials. Thanks to the rapid development in nano-fabrication and numerical modeling technologies, photonic nano-structures such as metamaterials and photonic crystals and various optical devices made by these optical materials create many novel applications and offer new prospects for manipulating light. For instance, both metamaterials and photonic crystals can exhibit negative refraction and negative refractive indexes. As a result, superlens with the capability of achieving imaging with sub-wavelength resolution can be realized. In this dissertation, a new negative index metamaterial architecture based on metallic nanoclusters, negative refraction phenomena in photonic crystals and optical devices implemented with negative index photonic crystals for imaging applications are presented. The nanocluster based metamaterials, which utilizes the magnetic Mie resonances of clusters of metallic inclusions, allow us to achieve negative index materials at optical frequency region. Meanwhile, bottom-up fabrication techniques such as self-assembly can be used, which is suitable for large-scale manufacturing and applicable to 3D structures. On the other hand, negative refraction and sub-wavelength imaging by a mechanically tunable photonic crystal structure were investigated. Using a honeycomb lattice photonic crystal composed of a silicon-polyimide membrane, a mechanically tunable superlens with a tunable frequency bandwidth was numerically demonstrated. Additionally, a graded negative index lens made of photonic crystals, which is capable of focusing plane waves, exhibits superior focusing properties such as low chromatic aberrations and broadband operation. Prisms structures made of negative index photonic crystals can offer useful imaging properties such as image inversion and magnification. These devices have the

  11. 网络低俗化对大学生负面影响及对策研究%On Network Vulgar Negative Impact on College Students and Countermeasures

    Institute of Scientific and Technical Information of China (English)

    冯曦鹏; 何云峰; 王静

    2015-01-01

    互联网技术的发展使人类社会生活进入了一个崭新的时代———网络时代。它给我们的生活带来便捷的同时也给人类社会的发展带来挑战和困惑,其中网络低俗化问题已经成为一个不容忽视的问题,其具体表现为网络成瘾现象严重、网络淫秽信息泛滥、网络暴力言论多发、网络诈骗事件频发等,应从“三观”教育、心理健康、行为方式等三个层面了解网络低俗化的负面影响,并从家庭学校教育、社会技术监管、政府法规建设、学生自我主体修养等方面采取相应的对策,以此来营造一个健康的网络环境。%The development of the Internet technology has made the life of human beings into a new brand era --the Internet age. It brings convenience as well as challenges and confusions to our lives.Especially, the network vulgarization problem has become an ignorable serious problem which shows as: the serious Internet addiction; network bawdy information; network speech violence; and frequent network fraud.This essay, from the three levels of the education of"three outlooks, mental health and behavior focuses, ana-lyses the negative effects of network vulgarization, and puts forward the corresponding countermeasures from the family and school edu-cation, social supervision, construction of government regulations, and the student main body self cultivation to create a healthy net-work environment.

  12. Ecological Impacts of Diesel Engine Emissions

    OpenAIRE

    Jurić, Vanja; Županović, Dino

    2012-01-01

    This article deals with the ecological impacts of chemical substances that are found in the structure of Diesel engine exhaust gases and provides an overview of legislation that limits their maximum allowable emissions. Special consideration is given to the previously mostly neglected negative impact of particulate matter compared to the impact of carbon dioxide. Negative impact of particulates is especially noted as direct negative impact on human health whereby the expenses associated with ...

  13. Three chamber negative ion source

    International Nuclear Information System (INIS)

    A negative ion vessel is divided into an excitation chamber, a negative ionization chamber and an extraction chamber by two magnetic filters. Input means introduces neutral molecules into a first chamber where a first electron discharge means vibrationally excites the molecules which migrate to a second chamber. In the second chamber a second electron discharge means ionizes the molecules, producing negative ions which are extracted into or by a third chamber. A first magnetic filter prevents high energy electrons from entering the negative ionization chamber from the excitation chamber. A second magnetic filter prevents high energy electrons from entering the extraction chamber from the negative ionizing chamber. An extraction grid at the end of the negative ion vessel attracts negative ions into the third chamber and accelerates them. Another grid, located adjacent to the extraction grid, carries a small positive voltage in order to inhibit positive ions from migrating into the extraction chamber and contour the plasma potential. Additional electrons can be suppressed from the output flux using ExB forces provided by magnetic field means and the extractor grid electric potential

  14. Tunable acoustic double negativity metamaterial.

    Science.gov (United States)

    Liang, Z; Willatzen, M; Li, J; Christensen, J

    2012-01-01

    Man-made composite materials called "metamaterials" allow for the creation of unusual wave propagation behavior. Acoustic and elastic metamaterials in particular, can pave the way for the full control of sound in realizing cloaks of invisibility, perfect lenses and much more. In this work we design acousto-elastic surface modes that are similar to surface plasmons in metals and on highly conducting surfaces perforated by holes. We combine a structure hosting these modes together with a gap material supporting negative modulus and collectively producing negative dispersion. By analytical techniques and full-wave simulations we attribute the observed behavior to the mass density and bulk modulus being simultaneously negative. PMID:23152948

  15. Acoustic metamaterial with negative density

    International Nuclear Information System (INIS)

    We fabricated a one-dimensional acoustic metamaterial with negative effective density using an array of very thin elastic membranes. We observed acoustic equivalence of the plasma oscillation at ωc=735 Hz. The metamaterial was opaque in the frequency range from 0 to 735 Hz, and was transparent above 735 Hz. We report direct observation of negative acceleration in this acoustic medium below 735 Hz. The frequency characteristics of the metamaterial have the same form as that of metals with negative permittivity. We also provide a simple theory to explain the experimental results.

  16. Wages, Amenities and Negative Attitudes

    DEFF Research Database (Denmark)

    Waisman, Gisela; Larsen, Birthe

    interpret the negative effect on wages as evidence of labour market discrimination. We estimate the welfare effects of negative attitudes, through their wage and local amenities, for immigrants with different levels of skills, origin, gender and age.......We exploit the regional variation in negative attitudes towards immigrants to Sweden in order to analyse the consequences of the attitudes on immigrants welfare. We find that attitudes towards immigrants are of importance: they both affect their labour market outcomes and their quality of life. We...

  17. Ten Rules for Dealing with Negative Contributions in Social Media

    OpenAIRE

    Adriana Stránská; Václav Stříteský

    2015-01-01

    Social media is becoming a key part of business communication strategy. Despite all the advantages, social media also poses a threat to business reputation. Dissatisfied customers can reach a large audience and share their negative experiences with others. This paper deals with the impact of social media on the practice of public relations. The goal of the paper is to formulate a set of rules for dealing with negative contributions and generally with crisis communication in social media. It...

  18. Negative ions as a source of low energy neutral beams

    Energy Technology Data Exchange (ETDEWEB)

    Fink, J.H.

    1980-01-01

    Little consideration has been given to the impact of recent developments in negative ion source technology on the design of low energy neutral beam injectors. However, negative ion sources of improved operating efficiency, higher gas efficiency, and smaller beam divergence will lead to neutral deuterium injectors, operating at less than 100 keV, with better operating efficiencies and more compact layouts than can be obtained from positive ion systems.

  19. Detecting negative selection on recurrent mutations using gene genealogy

    OpenAIRE

    Ezawa, Kiyoshi; Landan, Giddy; Graur, Dan

    2013-01-01

    Background Whether or not a mutant allele in a population is under selection is an important issue in population genetics, and various neutrality tests have been invented so far to detect selection. However, detection of negative selection has been notoriously difficult, partly because negatively selected alleles are usually rare in the population and have little impact on either population dynamics or the shape of the gene genealogy. Recently, through studies of genetic disorders and genome-...

  20. Piezoelectric enhancement under negative pressure.

    Science.gov (United States)

    Kvasov, Alexander; McGilly, Leo J; Wang, Jin; Shi, Zhiyong; Sandu, Cosmin S; Sluka, Tomas; Tagantsev, Alexander K; Setter, Nava

    2016-01-01

    Enhancement of ferroelectric properties, both spontaneous polarization and Curie temperature under negative pressure had been predicted in the past from first principles and recently confirmed experimentally. In contrast, piezoelectric properties are expected to increase by positive pressure, through polarization rotation. Here we investigate the piezoelectric response of the classical PbTiO3, Pb(Zr,Ti)O3 and BaTiO3 perovskite ferroelectrics under negative pressure from first principles and find significant enhancement. Piezoelectric response is then tested experimentally on free-standing PbTiO3 and Pb(Zr,Ti)O3 nanowires under self-sustained negative pressure, confirming the theoretical prediction. Numerical simulations verify that negative pressure in nanowires is the origin of the enhanced electromechanical properties. The results may be useful in the development of highly performing piezoelectrics, including lead-free ones. PMID:27396411

  1. Negative Database for Data Security

    CERN Document Server

    Patel, Anup; Eirinaki, Magdalini

    2011-01-01

    Data Security is a major issue in any web-based application. There have been approaches to handle intruders in any system, however, these approaches are not fully trustable; evidently data is not totally protected. Real world databases have information that needs to be securely stored. The approach of generating negative database could help solve such problem. A Negative Database can be defined as a database that contains huge amount of data consisting of counterfeit data along with the real data. Intruders may be able to get access to such databases, but, as they try to extract information, they will retrieve data sets that would include both the actual and the negative data. In this paper we present our approach towards implementing the concept of negative database to help prevent data theft from malicious users and provide efficient data retrieval for all valid users.

  2. Negative effects of positive reinforcement

    OpenAIRE

    Perone, Michael

    2003-01-01

    Procedures classified as positive reinforcement are generally regarded as more desirable than those classified as aversive—those that involve negative reinforcement or punishment. This is a crude test of the desirability of a procedure to change or maintain behavior. The problems can be identified on the basis of theory, experimental analysis, and consideration of practical cases. Theoretically, the distinction between positive and negative reinforcement has proven difficult (some would say t...

  3. Does individualism bring happiness? Negative effects of individualism on interpersonal relationships and happiness

    OpenAIRE

    Yuji eOgihara; Yukiko eUchida

    2014-01-01

    We examined the negative effects of individualism in an East Asian culture. Although individualistic systems decrease interpersonal relationships through competition, individualistic values have prevailed in European American cultures. One reason is because individuals could overcome negativity by actively constructing interpersonal relationships. In contrast, people in East Asian cultures do not have such strategies to overcome the negative impact of individualistic systems, leading to decre...

  4. Negativity Bias in Dangerous Drivers.

    Science.gov (United States)

    Chai, Jing; Qu, Weina; Sun, Xianghong; Zhang, Kan; Ge, Yan

    2016-01-01

    The behavioral and cognitive characteristics of dangerous drivers differ significantly from those of safe drivers. However, differences in emotional information processing have seldom been investigated. Previous studies have revealed that drivers with higher anger/anxiety trait scores are more likely to be involved in crashes and that individuals with higher anger traits exhibit stronger negativity biases when processing emotions compared with control groups. However, researchers have not explored the relationship between emotional information processing and driving behavior. In this study, we examined the emotional information processing differences between dangerous drivers and safe drivers. Thirty-eight non-professional drivers were divided into two groups according to the penalty points that they had accrued for traffic violations: 15 drivers with 6 or more points were included in the dangerous driver group, and 23 drivers with 3 or fewer points were included in the safe driver group. The emotional Stroop task was used to measure negativity biases, and both behavioral and electroencephalograph data were recorded. The behavioral results revealed stronger negativity biases in the dangerous drivers than in the safe drivers. The bias score was correlated with self-reported dangerous driving behavior. Drivers with strong negativity biases reported having been involved in mores crashes compared with the less-biased drivers. The event-related potentials (ERPs) revealed that the dangerous drivers exhibited reduced P3 components when responding to negative stimuli, suggesting decreased inhibitory control of information that is task-irrelevant but emotionally salient. The influence of negativity bias provides one possible explanation of the effects of individual differences on dangerous driving behavior and traffic crashes. PMID:26765225

  5. Atomic negative-ion resonances

    International Nuclear Information System (INIS)

    The authors attempt to give a comprehensive discussion of observations of atomic negative-ion resonances throughout the periodic table. A review of experimental and theoretical approaches to the study of negative-ion resonances is given together with a consideration of the various schemes that are used for their classification. In addition to providing, where possible, tabulated data for the energies, widths, and symmetries of these states, the authors also attempt to highlight regularities in their behavior both within groups of the periodic table and along isoionic sequences

  6. Sigma models with negative curvature

    Science.gov (United States)

    Alonso, Rodrigo; Jenkins, Elizabeth E.; Manohar, Aneesh V.

    2016-05-01

    We construct Higgs Effective Field Theory (HEFT) based on the scalar manifold Hn, which is a hyperbolic space of constant negative curvature. The Lagrangian has a non-compact O (n , 1) global symmetry group, but it gives a unitary theory as long as only a compact subgroup of the global symmetry is gauged. Whether the HEFT manifold has positive or negative curvature can be tested by measuring the S-parameter, and the cross sections for longitudinal gauge boson and Higgs boson scattering, since the curvature (including its sign) determines deviations from Standard Model values.

  7. Sigma Models with Negative Curvature

    CERN Document Server

    Alonso, Rodrigo; Manohar, Aneesh V

    2016-01-01

    We construct Higgs Effective Field Theory (HEFT) based on the scalar manifold H^n, which is a hyperbolic space of constant negative curvature. The Lagrangian has a non-compact O(n,1) global symmetry group, but it gives a unitary theory as long as only a compact subgroup of the global symmetry is gauged. Whether the HEFT manifold has positive or negative curvature can be tested by measuring the S-parameter, and the cross sections for longitudinal gauge boson and Higgs boson scattering, since the curvature (including its sign) determines deviations from Standard Model values.

  8. 应激事件、负性思维和应对方式对研究生抑郁的预测及影响研究%Prediction and impacts of stressful events,negative thoughts and coping styles on depression among graduate students

    Institute of Scientific and Technical Information of China (English)

    张俐; 张霞; 刘晓雨; 靳灿灿; 刘云波; 王晓霞

    2015-01-01

    目的:探究应激事件、负性思维和应对方式对高校研究生抑郁的预测及影响,为制定针对性的心理干预措施提供依据。方法采用 SDS 量表、青少年应激事件量表、简易应对方式问卷和自动思维问卷,对659名研究生进行调查。结果抑郁检出率为3.49%(23例),研究生抑郁与应激事件、负性思维和消极应对呈正相关(r =0.235、0.289、0.187,P 值均<0.01),与积极应对呈负相关(r=0.399,P <0.01);多元回归分析显示,应激事件与抑郁无线性关系,负性思维、积极应对和消极应对对抑郁有影响,其中积极应对预测力最强(15.9%)。结论高校研究生存在一定的抑郁人群,应针对性地制定心理干预措施,提高其心理健康水平。%Objective To study prediction and impacts of stressful events,negative thoughts and coping styles on depression among graduate students in colleges;to provide basis for making targeted psychological intervention measures.Methods A to-tal of 659 graduate students were investigated with Self-Rating Depression Scale (SDS),Adolescent Self-Rating Life Events Check List,Simplified Coping Style Questionnaire and Automatic Thoughts Questionnaire.Results The depression rate was 3.49%(23 cases).Depression among graduate students was positively correlated with stressful events,negative thoughts and negative coping style(r=0.235,0.289,0.187,all P <0.01);depression correlated negatively with positive coping style(r=0.399,P <0.01).Multivariate regression analysis showed no distinctive linear relationship between depressions and stressful events,depression was influenced by negative thoughts,positive coping style and negative coping style,among which positive coping style was the most powerful variable for depression predication(15.9%).Conclusion Some graduate students in colle-ges were suffered from depression.Targeted psychological interventions should be carried out to

  9. Food Inequality Negatively Impacts Cardiac Health in Rabbits

    OpenAIRE

    Fatemeh Heidary; Mohammad Reza Vaez Mahdavi; Farshad Momeni; Bagher Minaii; Mehrdad Rogani; Nader Fallah; Roghayeh Heidary; Reza Gharebaghi

    2008-01-01

    BACKGROUND: Individuals with lower socioeconomic status experience higher rates of mortality and are more likely to suffer from numerous diseases. While some studies indicate that humans who suffer from social inequality suffer generally worse health, to our knowledge no controlled experiments of this nature have been done in any species. Lipofuscin is a highly oxidized cross-linked aggregate consisting of oxidized protein and lipid clusters. This eminent terminal oxidation outcome accumulate...

  10. Negative impact of inorganic pollutants transport from landfill

    International Nuclear Information System (INIS)

    Heavy metals concentrations are evaluated in four sampling stations located in the Almendares river to estimate the influence of the leachate from 100 street landfill. The studied metals were Ni, Cr, Cd, Pb, Cu and Zn and the determinations were carried out in waters and sediments in March 2004. In the case of the waters the contents of dissolved metals were low, in most of the cases less than the levels recommended in the drinking water guidelines for Cuba. The high organic matter content and pH values of the water (higher to 7) are factors that may contribute to the precipitation of metals. The contents of metals in the river Almendares sediments were high in most of the cases. The highest metals levels were found in the sampling station located near the landfill. A decrease of the metals content was verified in the sediments when the distance of the evaluated polluting source was increased. Taken into account the enrichment factors for Cr, Cd, Pb, Cu y Zn the total content surpass the level for a lithogenous material. Furthermore, it shows the importance of the anthropogenic metals inputs. Using the method of sequential extractions we found that the organic matter in the sediment fulfils an important role in the immobilization of the metals. The results obtained in the investigation indicate that 100 street leachate could constitute an important source of contamination of the river related to heavy metals. That's why it is necessary to implement a solution for the treatment of the leachate or for to avoid the disposition in the river

  11. The negative impact of technological accidents on the consumers behaviors

    International Nuclear Information System (INIS)

    After the accidental release in the Tricastin site, the wine producers of this region where grows a vineyard with a protected designation of origin (A.O.C. in French legislation) noticed a consistent decrease of their sales. This consumers behavior is not rational because the vineyard is far from the area concerned by this accidental pollution. Face to an open market, the consumer has a freedom of choice that allows him to reject a product on which a sanitary suspicion presses. That is what shows an inquiry made by students in France. The consequences of an accident are not only linked to the sanitary safety or environmental stakes but depends on economical mechanisms such image or attractiveness loss. (N.C.)

  12. Positive and negative impact of increased tertiary attainment

    OpenAIRE

    2013-01-01

    The theory of human capital clearly states that the investments into the education bring many benefits and are worth the cost. The OECD Education at a Glance analysis provides support for both public and private investing in tertiary education as the net present value is positive for all observed countries. Considering the benefits of education, a growth in tertiary education should be viewed very positively. In this context, the European Strategy Europe 2020 set up one of its main goals for ...

  13. Climate change policy positive or negative economic impact? Why?

    NARCIS (Netherlands)

    Kupers, R.T.L.; Mangalagiu, D.

    2010-01-01

    ECF initiates and performs high-class research on climate change in close interaction with stakeholders. We provide a pluralistic communication platform in the emerging global field of researchers, governments, local authorities, businesses, and social movements. This field lies beyond the tradition

  14. Youth sport: positive and negative impact on young athletes.

    Science.gov (United States)

    Merkel, Donna L

    2013-01-01

    Organized youth sports are highly popular for youth and their families, with approximately 45 million children and adolescent participants in the US. Seventy five percent of American families with school-aged children have at least one child participating in organized sports. On the surface, it appears that US children are healthy and happy as they engage in this traditional pastime, and families report higher levels of satisfaction if their children participate. However, statistics demonstrate a childhood obesity epidemic, with one of three children now being overweight, with an increasingly sedentary lifestyle for most children and teenagers. Increasing sports-related injuries, with 2.6 million emergency room visits a year for those aged 5-24 years, a 70%-80% attrition rate by the time a child is 15 years of age, and programs overemphasizing winning are problems encountered in youth sport. The challenges faced by adults who are involved in youth sports, from parents, to coaches, to sports medicine providers, are multiple, complex, and varied across ethnic cultures, gender, communities, and socioeconomic levels. It appears that an emphasis on fun while establishing a balance between physical fitness, psychologic well-being, and lifelong lessons for a healthy and active lifestyle are paramount for success. PMID:24379720

  15. Youth sport: positive and negative impact on young athletes

    OpenAIRE

    Merkel DL

    2013-01-01

    Donna L Merkel Bryn Mawr Rehabilitation Hospital, Main Line Health System, Exton, PA, USA Abstract: Organized youth sports are highly popular for youth and their families, with approximately 45 million children and adolescent participants in the US. Seventy five percent of American families with school-aged children have at least one child participating in organized sports. On the surface, it appears that US children are healthy and happy as they engage in this traditional pastime, and famili...

  16. Youth sport: positive and negative impact on young athletes

    Directory of Open Access Journals (Sweden)

    Merkel DL

    2013-05-01

    Full Text Available Donna L Merkel Bryn Mawr Rehabilitation Hospital, Main Line Health System, Exton, PA, USA Abstract: Organized youth sports are highly popular for youth and their families, with approximately 45 million children and adolescent participants in the US. Seventy five percent of American families with school-aged children have at least one child participating in organized sports. On the surface, it appears that US children are healthy and happy as they engage in this traditional pastime, and families report higher levels of satisfaction if their children participate. However, statistics demonstrate a childhood obesity epidemic, with one of three children now being overweight, with an increasingly sedentary lifestyle for most children and teenagers. Increasing sports-related injuries, with 2.6 million emergency room visits a year for those aged 5–24 years, a 70%–80% attrition rate by the time a child is 15 years of age, and programs overemphasizing winning are problems encountered in youth sport. The challenges faced by adults who are involved in youth sports, from parents, to coaches, to sports medicine providers, are multiple, complex, and varied across ethnic cultures, gender, communities, and socioeconomic levels. It appears that an emphasis on fun while establishing a balance between physical fitness, psychologic well-being, and lifelong lessons for a healthy and active lifestyle are paramount for success. Keywords: youth sports, injuries, benefits, risks, prevention, specialization

  17. The Negative Impact of Organizational Cynicism on Physicians and Nurses

    OpenAIRE

    Volpe, Rebecca L.; Mohammed, Susan; Hopkins, Margaret; Shapiro, Daniel; Dellasega, Cheryl

    2014-01-01

    Despite the potentially severe consequences that could result, there is a paucity of research on organizational cynicism within US healthcare providers. In response, this study investigated the effect of cynicism on organizational commitment, job satisfaction, and interest in leaving the hospital for another job in a sample of 205 physicians and 842 nurses. Three types of cynicism were investigated: trait (dispositional), global (directed toward the hospital), and local (directed toward a spe...

  18. EFFECTS OF MEDICAL DISPUTES ON INTERNET COMMUNICATIONS OF NEGATIVE EMOTIONS AND NEGATIVE ONLINE WORD-OF-MOUTH.

    Science.gov (United States)

    Lee, Yi-Chih; Wu, Wei-Li

    2015-08-01

    Emotions play an important role in human behavior. Negative emotions resulting from medical disputes are problems for medical personnel to solve but also have a significant impact on a hospital's reputation and people's trust in the hospital. One medical dispute case was chosen from an Internet news source to assess the correlation between people's negative emotions and negative online word-of-mouth. Convenience sampling was used in school faculties and university students who had shared their medical treatment experiences online were the research participants. A total of 221 Taiwanese participants volunteered (158 women, 63 men; ages: 26.7% under 19, 22.6% 20-29, 30.8% 30-39,19.9% over 40). Four negative emotions were measured using rating scales: uncertainty, anger, disappointment, and sadness. Four negative online word-of-mouth measures were: venting, advice search, helping receiver, and revenge. A modeled relationship was assessed by partial least square method (PLS). Then, people's positive emotions were further analyzed to assess changes after spreading negative word-of-mouth. The results showed that uncertainty had a positive effect on venting and advice search. People who felt anger or regret spread word-of-mouth in order to help the receiver. Disappointment may trigger the revenge behavior of negative word-of-mouth. Negative emotions could be relieved after engaging in the behavior of helping the receiver. PMID:26226491

  19. The first Robin eigenvalue with negative boundary parameter

    Czech Academy of Sciences Publication Activity Database

    Freitas, P.; Krejčiřík, David

    2015-01-01

    Roč. 280, AUG (2015), s. 322-339. ISSN 0001-8708 R&D Projects: GA ČR(CZ) GA14-06818S Institutional support: RVO:61389005 Keywords : Eigenvalue optimisation * Laplacian * Robin boundary condition * negative parameter * asymptotics * disproval of Bareket's conjecture Subject RIV: BE - Theoretical Physics Impact factor: 1.294, year: 2014

  20. Room temperature negative differential resistance in molecular nanowires

    Czech Academy of Sciences Publication Activity Database

    Kratochvílová, Irena; Kočiřík, Milan; Zambova, A.; Mbindyo, J.; Mallouk, T. E.; Mayer, T. S.

    2002-01-01

    Roč. 12, - (2002), s. 2927-2930. ISSN 0959-9428 R&D Projects: GA AV ČR IAA1040101 Institutional research plan: CEZ:AV0Z1010914 Keywords : nanowires * negative differential resistance * electric-field assembly Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.683, year: 2002

  1. The opportunity cost of negative screening in socially responsible investing

    NARCIS (Netherlands)

    Trinks, Pieter Jan; Scholtens, Lambertus

    2016-01-01

    This paper investigates the impact of negative screening on the investment universe as well as on financial performance. We come up with a novel identification process and as such depart from mainstream Socially Responsible Investing (SRI) literature by concentrating on individual firms’ conduct and

  2. NEGATIVE EFFECT OF METALLOID STRESS ON WHEAT

    Directory of Open Access Journals (Sweden)

    Marína Maglovski

    2015-02-01

    Full Text Available Arsenic (As belongs to heavy metals and its accumulation in plants, besides damaging the organism itself, represents a potential health risk to animal and human consumers. Therefore, contamination of soils and waters with this compound is a serious environmental problem. In this work we focused on investigating a negative impact of As on selected parameters of growth of wheat plants (Triticum aestivum L. cv. Genoveva grown in hydropony. In the stage of first assimilation leaves we applied a solution of heavy metal (1 mg.kg-1 As3+ on wheat plants. For plants grown under hydropony conditions we observed different plant parameters such as length, weight, amount of fresh and dry biomass. Further we analyzed accumulation of hydrogen peroxide and products membrane lipid peroxidation as indicators of oxidative stress. In addition to these we also measured the content of photosynthetic pigments, maximal quantum yield and proline in plant tissue. Our data indicate reduction of the biomass of shoots forthcoming as a result of exposure of stressed plants to As. Decline of biomass accumulation was accompanied by increase of hydrogen peroxide in plant tissue. In contrast, level of lipid peroxidation was suppressed in stressed shoots. Contents of photosynthetic pigments soundly decreased. Interestingly, fluorescence (Fp=Fm in stressed wheat shoots increased. Similarly in tested shoots the content of proline was increased. The results indicate that the applied dose of As has a negative impact on the growth and photosynthetic performance of stressed plants. A better understanding of the mechanisms responsible for As resistance and toxicity in plants requires further investigation.

  3. Underpowered samples, false negatives, and unconscious learning.

    Science.gov (United States)

    Vadillo, Miguel A; Konstantinidis, Emmanouil; Shanks, David R

    2016-02-01

    The scientific community has witnessed growing concern about the high rate of false positives and unreliable results within the psychological literature, but the harmful impact of false negatives has been largely ignored. False negatives are particularly concerning in research areas where demonstrating the absence of an effect is crucial, such as studies of unconscious or implicit processing. Research on implicit processes seeks evidence of above-chance performance on some implicit behavioral measure at the same time as chance-level performance (that is, a null result) on an explicit measure of awareness. A systematic review of 73 studies of contextual cuing, a popular implicit learning paradigm, involving 181 statistical analyses of awareness tests, reveals how underpowered studies can lead to failure to reject a false null hypothesis. Among the studies that reported sufficient information, the meta-analytic effect size across awareness tests was d z = 0.31 (95 % CI 0.24-0.37), showing that participants' learning in these experiments was conscious. The unusually large number of positive results in this literature cannot be explained by selective publication. Instead, our analyses demonstrate that these tests are typically insensitive and underpowered to detect medium to small, but true, effects in awareness tests. These findings challenge a widespread and theoretically important claim about the extent of unconscious human cognition. PMID:26122896

  4. The negative emotional impact of cognitive-behavioral intervention on high school students with chronic hepatitis B virus carriers%认知行为干预对高中生慢性乙型肝炎病毒携带者负性情绪的影响

    Institute of Scientific and Technical Information of China (English)

    李静娣; 陈桂凤; 张静

    2010-01-01

    目的 探讨认知行为干预对高中生慢性乙型肝炎病毒携带者负性情绪的影响.方法 将120例体检的高中生慢性乙型肝炎病毒携带者随机分为对照组和观察组各60例,对照组按常规的方法进行宣教;观察组在常规的宣教方法基础上采用认知行为干预.分别在干预前及干预后第6周进行焦虑自评量表(SAS)和抑郁自评量表(SDS)评定.结果 干预后2组对象SAS、SDS评分较干预前下降(P<0.05),观察组与对照组比较,差异有统计学意义(P<0.05).结论 认知行为干预能改善高中生慢性乙型肝炎病毒携带者负性情绪,帮助其矫正不良认知,重塑健康行为,保持乐观自信的良好个性.%Objective To investigate the negative emotional impact of cognitive-behavioral intervention on high school students with chronic hepatitis B virus carriers. Methods A total of 120 cases of high school students with chronic hepatitis B virus carriers who received physical examination were randomly divided into control group and observation group (60 cases respectively ). The cases in the control group received conventional methods, while those in experiment group received cognitive-behavioral intervention . Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were assessed before and 6 months postintervention between groups. Results The SAS, SDS score were lower after 6 months intervention than before the intervention in two groups ( P < 0. 05 ). The SAS, SDS score reduced much more in experiment group than those in the control group ( P < 0. 05 ). Conclusions Cognitive-behavioral intervention can improve the negative emotions of high school students with chronic hepatitis B virus carriers, help them correct the negative perception, reshape health behavior, self-confident optimism and a good personality.

  5. Negation switching invariant signed graphs

    Directory of Open Access Journals (Sweden)

    Deepa Sinha

    2014-04-01

    Full Text Available A signed graph (or, $sigraph$ in short is a graph G in which each edge x carries a value $\\sigma(x \\in \\{-, +\\}$ called its sign. Given a sigraph S, the negation $\\eta(S$ of the sigraph S is a sigraph obtained from S by reversing the sign of every edge of S. Two sigraphs $S_{1}$ and $S_{2}$ on the same underlying graph are switching equivalent if it is possible to assign signs `+' (`plus' or `-' (`minus' to vertices of $S_{1}$ such that by reversing the sign of each of its edges that has received opposite signs at its ends, one obtains $S_{2}$. In this paper, we characterize sigraphs which are negation switching invariant and also see for what sigraphs, S and $\\eta (S$ are signed isomorphic.

  6. Cosmology with negative absolute temperatures

    Science.gov (United States)

    Vieira, J. P. P.; Byrnes, Christian T.; Lewis, Antony

    2016-08-01

    Negative absolute temperatures (NAT) are an exotic thermodynamical consequence of quantum physics which has been known since the 1950's (having been achieved in the lab on a number of occasions). Recently, the work of Braun et al. [1] has rekindled interest in negative temperatures and hinted at a possibility of using NAT systems in the lab as dark energy analogues. This paper goes one step further, looking into the cosmological consequences of the existence of a NAT component in the Universe. NAT-dominated expanding Universes experience a borderline phantom expansion (w < ‑1) with no Big Rip, and their contracting counterparts are forced to bounce after the energy density becomes sufficiently large. Both scenarios might be used to solve horizon and flatness problems analogously to standard inflation and bouncing cosmologies. We discuss the difficulties in obtaining and ending a NAT-dominated epoch, and possible ways of obtaining density perturbations with an acceptable spectrum.

  7. Dynamically variable negative stiffness structures

    Science.gov (United States)

    Churchill, Christopher B.; Shahan, David W.; Smith, Sloan P.; Keefe, Andrew C.; McKnight, Geoffrey P.

    2016-01-01

    Variable stiffness structures that enable a wide range of efficient load-bearing and dexterous activity are ubiquitous in mammalian musculoskeletal systems but are rare in engineered systems because of their complexity, power, and cost. We present a new negative stiffness–based load-bearing structure with dynamically tunable stiffness. Negative stiffness, traditionally used to achieve novel response from passive structures, is a powerful tool to achieve dynamic stiffness changes when configured with an active component. Using relatively simple hardware and low-power, low-frequency actuation, we show an assembly capable of fast (100×) dynamic stiffness control. This approach mitigates limitations of conventional tunable stiffness structures that exhibit either small (humanoid robotic limbs and lightweight adaptive vibration isolators. PMID:26989771

  8. Closed incision negative pressure therapy

    DEFF Research Database (Denmark)

    Willy, Christian; Agarwal, Animesh; Andersen, Charles A;

    2016-01-01

    Surgical site occurrences (SSOs) affect up to or over 25% of patients undergoing operative procedures, with the subset of surgical site infections (SSIs) being the most common. Commercially available closed incision negative pressure therapy (ciNPT) may offer surgeons an additional option to manage...... of Controlled Trials using key words 'prevention', 'negative pressure wound therapy (NPWT)', 'active incisional management', 'incisional vacuum therapy', 'incisional NPWT', 'incisional wound VAC', 'closed incisional NPWT', 'wound infection', and 'SSIs' identified peer-reviewed studies published from 2000....... A majority presented data supporting ciNPT use. Numerous publications reported SSI risk factors, with the most common including obesity (body mass index ≥30 kg/m(2) ); diabetes mellitus; tobacco use; or prolonged surgical time. We recommend that the surgeon assess the individual patient's risk factors...

  9. Photosynthesis and negative entropy production.

    Science.gov (United States)

    Jennings, Robert C; Engelmann, Enrico; Garlaschi, Flavio; Casazza, Anna Paola; Zucchelli, Giuseppe

    2005-09-30

    The widely held view that the maximum efficiency of a photosynthetic pigment system is given by the Carnot cycle expression (1-T/Tr) for energy transfer from a hot bath (radiation at temperature Tr) to a cold bath (pigment system at temperature T) is critically examined and demonstrated to be inaccurate when the entropy changes associated with the microscopic process of photon absorption and photochemistry at the level of single photosystems are considered. This is because entropy losses due to excited state generation and relaxation are extremely small (DeltaS 0.98 and xi > 0.92 respectively, and which, in principle, function with negative entropy production. It is demonstrated that for the case of xi > (1-T/Tr) entropy production is always negative and only becomes positive when xi < (1-T/Tr). PMID:16139784

  10. Proclus’ View about Negative Theology

    Directory of Open Access Journals (Sweden)

    S Rahimiyan

    2012-09-01

    Full Text Available Negative theology is a modern theological approach that idiomatically implies those theological doctrines which are based on the negative premises and concepts for describing God. Among Greeks, this approach was on its climax in Neo-Platonism. Proclus is one of the Neo-Platonists who lived in fifth century (A.D and was in charge of Athena academy for years. He was the most important Neo-Platonist after Plotinus. In his philosophical system, on the one hand, it is impossible to recognize the first source and, on the other hand, the existence of some principles like the relationship between the creator and the universe, reversion and the way of emanation receiving, requires the knowledge of the first source. It seems that such paradox can be resolved by separating the stages of existence order.

  11. Cosmology with Negative Absolute Temperatures

    CERN Document Server

    Vieira, J P P; Lewis, Antony

    2016-01-01

    Negative absolute temperatures (NAT) are an exotic thermodynamical consequence of quantum physics which has been known since the 1950's (having been achieved in the lab on a number of occasions). Recently, the work of Braun et al (2013) has rekindled interest in negative temperatures and hinted at a possibility of using NAT systems in the lab as dark energy analogues. This paper goes one step further, looking into the cosmological consequences of the existence of a NAT component in the Universe. NAT-dominated expanding Universes experience a borderline phantom expansion ($w<-1$) with no Big Rip, and their contracting counterparts are forced to bounce after the energy density becomes sufficiently large. Both scenarios might be used to solve horizon and flatness problems analogously to standard inflation and bouncing cosmologies. We discuss the difficulties in obtaining and ending a NAT-dominated epoch, and possible ways of obtaining density perturbations with an acceptable spectrum.

  12. Can wormholes have negative temperatures?

    OpenAIRE

    Hong, Soon-Tae; Kim, Sung-Won

    2003-01-01

    We study (3+1) Morris-Thorne wormhole to investigate its higher dimensional embedding structures and thermodynamic properties. It is shown that the wormhole is embedded in (5+2) global embedding Minkowski space. This embedding enables us to construct the wormhole entropy and Hawking temperature by exploiting Unruh effects. We also propose a possibility of negative temperature originated from exotic matter distribution of the wormhole.

  13. Mismatch Negativity: Translating the Potential

    OpenAIRE

    JuanitaTodd

    2013-01-01

    The mismatch negativity (MMN) component of the auditory event-related potential has become a valuable tool in cognitive neuroscience. Its reduced size in persons with schizophrenia is of unknown origin but theories proposed include links to problems in experience-dependent plasticity reliant on N-methyl-d-aspartate glutamate receptors. In this review we address the utility of this tool in revealing the nature and time course of problems in perceptual inference in this illness together with it...

  14. Negative muon spin rotation experiment

    International Nuclear Information System (INIS)

    Results of the experimental project using negative muon spin rotation at Lawrence Berkeley Laboratory are reported. The following were discussed briefly: the bound muon g factors from the viewpoints of the relativistic and nuclear polarization effects, strange depolarization phenomena in terms of the difference between the muonic-atom probe and its equivalent nuclear probe, application of the μ- 0 probe to studies of magnetic oxides, and total muon capture rates in the actinide region. (U.S.)

  15. Quantum Complexity and Negative Curvature

    CERN Document Server

    Brown, Adam R; Zhao, Ying

    2016-01-01

    As time passes, once simple quantum states tend to become more complex. For strongly coupled k-local Hamiltonians, this growth of computational complexity has been conjectured to follow a distinctive and universal pattern. In this paper we show that the same pattern is exhibited by a much simpler system: classical geodesics on a compact two-dimensional geometry of uniform negative curvature. This striking parallel persists whether the system is allowed to evolve naturally or is perturbed from the outside.

  16. Quantum information can be negative

    OpenAIRE

    Horodecki, Michal; Oppenheim, Jonathan; Winter, Andreas

    2005-01-01

    Given an unknown quantum state distributed over two systems, we determine how much quantum communication is needed to transfer the full state to one system. This communication measures the "partial information" one system needs conditioned on it's prior information. It turns out to be given by an extremely simple formula, the conditional entropy. In the classical case, partial information must always be positive, but we find that in the quantum world this physical quantity can be negative. If...

  17. In defense of negative temperature

    Science.gov (United States)

    Poulter, J.

    2016-03-01

    This pedagogical comment highlights three misconceptions concerning the usefulness of the concept of negative temperature, being derived from the usual, often termed Boltzmann, definition of entropy. First, both the Boltzmann and Gibbs entropies must obey the same thermodynamic consistency relation. Second, the Boltzmann entropy does obey the second law of thermodynamics. Third, there exists an integrating factor of the heat differential with both definitions of entropy.

  18. Weak negation in inquisitive semantics

    Czech Academy of Sciences Publication Activity Database

    Punčochář, Vít

    2015-01-01

    Roč. 24, č. 3 (2015), s. 323-355. ISSN 0925-8531 R&D Projects: GA ČR(CZ) GA13-21076S Institutional support: RVO:67985955 Keywords : inquisitive semantics * negation * possible worlds * Fitch-style natural deduction * denial Subject RIV: AA - Philosophy ; Religion http://link.springer.com/article/10.1007%2Fs10849-015-9219-2

  19. 热态启动负温度匹配对转子应力及寿命影响分析%Impact Analysis of the Negative Temperature Mismatch of Hot Start-up on the Stress and Life of Rotors

    Institute of Scientific and Technical Information of China (English)

    李勇; 王晓波

    2015-01-01

    This paper takes a certain 330MW power plant turbine rotor as the research object .Choose the governing stage and the first high pressure stage as isolator to build a two-dimensional axisymmetric model .This paper got the thermal shock stress and maximum equivalent stress during start-up procedure under the condition of different temperatures mismatch with the help of the finite element analysis software ANSYS .The low cycle fatigue life consumption in the process of the start-up is calculated .The results show that the small latitude negative steam temperature mismatch will not impact security , thus reducing the fatigue life loss little .%以某电厂330MW汽轮机转子为研究对象,选取调节级及其高压压力级第一级为隔离体,运用ANSYS有限元软件建立二维轴对称模型,得到不同负温度匹配情况下的冲击热应力和启动过程中的最大应力,进而计算出启动过程中低周疲劳寿命损耗。结果表明:小幅度的负温度匹配不会影响启动过程的安全性,由此引起疲劳寿命损耗增加也很小。

  20. Perfect imaging without negative refraction

    OpenAIRE

    Leonhardt, Ulf

    2009-01-01

    Perfect imaging has been believed to rely on negative refraction, but here we show that an ordinary positively-refracting optical medium may form perfect images as well. In particular, we establish a mathematical proof that Maxwell's fish eye in two-dimensional integrated optics makes a perfect instrument with a resolution not limited by the wavelength of light. We also show how to modify the fish eye such that perfect imaging devices can be made in practice. Our method of perfect focusing ma...

  1. Perfect imaging without negative refraction

    CERN Document Server

    Leonhardt, Ulf

    2009-01-01

    Perfect imaging has been believed to rely on negative refraction, but here we show that an ordinary positively-refracting optical medium may form perfect images as well. In particular, we establish a mathematical proof that Maxwell's fish eye in two-dimensional integrated optics makes a perfect instrument with a resolution not limited by the wavelength of light. We also show how to modify the fish eye such that perfect imaging devices can be made in practice. Our method of perfect focusing may also find applications outside of optics, in acoustics, fluid mechanics or quantum physics, wherever waves obey the two-dimensional Helmholtz equation.

  2. Superluminal travel requires negative energies

    OpenAIRE

    Olum, Ken D.

    1998-01-01

    I investigate the relationship between faster-than-light travel and weak-energy-condition violation, i.e., negative energy densities. In a general spacetime it is difficult to define faster-than-light travel, and I give an example of a metric which appears to allow superluminal travel, but in fact is just flat space. To avoid such difficulties, I propose a definition of superluminal travel which requires that the path to be traveled reach a destination surface at an earlier time than any neig...

  3. Incisional Negative Pressure Wound Therapy

    DEFF Research Database (Denmark)

    Hyldig, Nana; Birke-Sorensen, Hanne; Kruse, Marie;

    incisions to reduce postoperative wound complications, though the evidence base to support this intervention is limited. The aim of this study was to assess if Negative Pressure Wound Therapy (NPWT) reduces postoperative complications when applied on closed surgical incisions. Method: A systematic review...... seroma formation (52%) compared to standard care. The reduction in wound dehiscence was not statistically significant. The numbers needed to treat were 3 (seroma), 17 (dehiscence), and 25 (infection). Methodical heterogeneity across studies led to downgrading quality of evidence to moderate for infection...

  4. Migration between Positive and Negative

    OpenAIRE

    Vancea Diane Paula Corina

    2012-01-01

    The migration phenomenon represents one of the most important issues equally for the recipient and source countries. This paper presents the effects of migration in Romania, as source country, from the point of view of market labour, education and consumption. Analysing the effects of migration we can conclude that is difficult for a country like Romania to draw a general conclusion. On the one hand, we can say that there are a lot of positive effects but on the other hand we remark negative ...

  5. Acoustic metamaterial with negative modulus

    International Nuclear Information System (INIS)

    We present experimental and theoretical results on an acoustic metamaterial that exhibits a negative effective modulus in a frequency range from 0 to 450 Hz. A one-dimensional acoustic metamaterial with an array of side holes on a tube was fabricated. We observed that acoustic waves above 450 Hz propagated well in this structure, but no sound below 450 Hz passed through. The frequency characteristics of the metamaterial has the same form as that of the permittivity in metals due to the plasma oscillation. We also provide a theory to explain the experimental results.

  6. Negative regulators of cell proliferation

    Science.gov (United States)

    Johnson, T. C.; Spooner, B. S. (Principal Investigator)

    1994-01-01

    Cell proliferation is governed by the influence of both mitogens and inhibitors. Although cell contact has long been thought to play a fundamental role in cell cycling regulation, and negative regulators have long been suspected to exist, their isolation and purification has been complicated by a variety of technical difficulties. Nevertheless, over recent years an ever-expanding list of putative negative regulators have emerged. In many cases, their biological inhibitory activities are consistent with density-dependent growth inhibition. Most likely their interactions with mitogenic agents, at an intracellular level, are responsible for either mitotic arrest or continued cell cycling. A review of naturally occurring cell growth inhibitors is presented with an emphasis on those factors shown to be residents of the cell surface membrane. Particular attention is focused on a cell surface sialoglycopeptide, isolated from intact bovine cerebral cortex cells, which has been shown to inhibit the proliferation of an unusually wide range of target cells. The glycopeptide arrest cells obtained from diverse species, both fibroblasts and epithelial cells, and a broad variety of transformed cells. Signal transduction events and a limited spectrum of cells that are refractory to the sialoglycopeptide have provided insight into the molecular events mediated by this cell surface inhibitor.

  7. Impact of Advertisement on Malay Young Consumers

    OpenAIRE

    Asif Khurshid; Aneel Salman; Nedim Makarevic

    2016-01-01

    The purpose of writing this paper is to explore the understanding of advertisement and its impact on young consumers. Also it was discussed that how this impact if it is negative can be neutralized. It has been identified after conducting in depth interviews that all respondents were of the opinion that advertisement is a source of communication. In addition to this all respondents are agreed that it has positive as well as negative effects on both children and young adults. Negative impacts ...

  8. Chiral Negative-Index Metamaterials in Terahertz

    OpenAIRE

    Zhang, Shuang; Park, Yong-Shik; Li, Jensen; Lu, Xinchao; Zhang, Weili; Zhang, Xiang

    2008-01-01

    Negative index metamaterials (NIMs) give rise to unusual and intriguing properties and phenomena, which may lead to important applications such as superlens, subwavelength cavity and slow light devices. However, the negative refractive index in metamaterials normally requires a stringent condition of simultaneously negative permittivity and negative permeability. A new class of negative index metamaterials - chiral NIMs, have been recently proposed. In contrast to the conventional NIMs, chira...

  9. Stability of Negative V'' Systems

    International Nuclear Information System (INIS)

    Negative-V'' systems are more intrinsically stable than shearstabilized systems in that they are completely stable to the pure interchange instability. However, they are unstable to a ballooning mode instability which is essentially a tied interchange localized to a part of a line of force which has adverse curvature. For infinite conductivity this mode leads to a critical value βc of β, the ratio of plasma to magnetic pressures, below which it is stable. This critical value is given by an approximate expression that involves: the relative variation ΔU/U of U = ∫dℓ/B, where the integration is over. the length L of the region of adverse curvature; and L. The variation is that from the axis to the boundary of the plasma at radius a. In its simplest form this formula is βc = g(U/ΔU) (π2a2/L2), where g is a constant of order one. This formula has been justified by a correct stability analysis for the negative-V'' systems of Johnson. If the.resistance of the plasma is nonzero, then the tying of the interchange by the regions of favorable curvature is relaxed and the ballooning mode becomes a resistive-ballooning mode. This mode is always unstable and for β c its growth rate is approximately oR = m2/βc τclass where m is the azimuthal mode number and τclass is the classical diffusion time. If the negative-V'' systems also have a sheared magnetic field, then oR is reduced for large m. Also, it is expected that oR is limited by finite gyration radius effects for large m. On the basis of these considerations it is speculated that the maximum effective value of m is about 10. Thus, βc becomes a figure of merit for the resistive-ballooning mode and must be comparable with one for a successful confinement system. Hence large ΔU/U or large L are unfavorable to stable confinement. (author)

  10. Congenital nystagmus and negative electroretinography

    Directory of Open Access Journals (Sweden)

    Roussi M

    2011-04-01

    Full Text Available Mirella Roussi, Hélène Dalens, Jean Jacques Marcellier, Franck BacinDepartment of Ophthalmology, Clermont-Ferrand University, Clermont-Ferrand, FranceAbstract: Congenital nystagmus is a pathologic oculomotor state appearing at about three to four months of age. The precise diagnosis requires detailed clinical examination and electrophysiological findings. This case report presents two male patients with congenital nystagmus examined longitudinally from the age of six months until 17-18 years of age. Clinical and electrophysiological protocols were detailed. The first results showed electronegative electroretinography in the two cases and examination combined with electroretinographic findings helped us to make the diagnosis of Congenital Night Stationary Blindness (CSNB. This diagnosis was confirmed by genetic studies. CSNB is interesting to study because through electrophysiological findings, it enables a better understanding of the physiology of neural transmission in the outer part of the retina.Keywords: Congenital nystagmus, negative electroretinography, congenital night stationary blindness

  11. Mondialization: The negation of territory

    Directory of Open Access Journals (Sweden)

    Đorđević Dejan

    2007-01-01

    Full Text Available The main objective of this paper is to present some weaknesses and inconsistence of the mondialization/globalization concept, especially regarding obvious negation of territoriality as a principle and a crude reality of uneven spatial distribution of resources, wealth and population on global scale. The domination of the globalism and neo-liberalism in the spheres of economy, society, culture and even language leads toward greater differences, in such intensity that some authors describe it as a "clash of civilizations". Loosing territoriality means loosing "raison d’etre" of spatial planning. Some efforts to introduce participation as a planning solution for the beginning of the new century is actually a Trojan horse and a step in the wrong direction.

  12. Entanglement negativity in the multiverse

    Energy Technology Data Exchange (ETDEWEB)

    Kanno, Sugumi [Department of Theoretical Physics and History of Science, University of the Basque Country UPV/EHU, 48080 Bilbao (Spain); IKERBASQUE, Basque Foundation for Science, Maria Diaz de Haro 3, 48013, Bilbao (Spain); Laboratory for Quantum Gravity & Strings and Astrophysics, Cosmology & Gravity Center, Department of Mathematics & Applied Mathematics, University of Cape Town, Private Bag, Rondebosch 7701 (South Africa); Shock, Jonathan P. [Laboratory for Quantum Gravity & Strings and Astrophysics, Cosmology & Gravity Center, Department of Mathematics & Applied Mathematics, University of Cape Town, Private Bag, Rondebosch 7701 (South Africa); National Institute for Theoretical Physics, Private Bag X1, Matieland, 7602 (South Africa); Soda, Jiro [Department of Physics, Kobe University, Kobe 657-8501 (Japan)

    2015-03-10

    We explore quantum entanglement between two causally disconnected regions in the multiverse. We first consider a free massive scalar field, and compute the entanglement negativity between two causally separated open charts in de Sitter space. The qualitative feature of it turns out to be in agreement with that of the entanglement entropy. We then introduce two observers who determine the entanglement between two causally disconnected de Sitter spaces. When one of the observers remains constrained to a region of the open chart in a de Sitter space, we find that the scale dependence enters into the entanglement. We show that a state which is initially maximally entangled becomes more entangled or less entangled on large scales depending on the mass of the scalar field and recovers the initial entanglement in the small scale limit. We argue that quantum entanglement may provide some evidence for the existence of the multiverse.

  13. Entanglement negativity in the multiverse

    International Nuclear Information System (INIS)

    We explore quantum entanglement between two causally disconnected regions in the multiverse. We first consider a free massive scalar field, and compute the entanglement negativity between two causally separated open charts in de Sitter space. The qualitative feature of it turns out to be in agreement with that of the entanglement entropy. We then introduce two observers who determine the entanglement between two causally disconnected de Sitter spaces. When one of the observers remains constrained to a region of the open chart in a de Sitter space, we find that the scale dependence enters into the entanglement. We show that a state which is initially maximally entangled becomes more entangled or less entangled on large scales depending on the mass of the scalar field and recovers the initial entanglement in the small scale limit. We argue that quantum entanglement may provide some evidence for the existence of the multiverse

  14. Incisional Negative Pressure Wound Therapy

    DEFF Research Database (Denmark)

    Hyldig, Nana

    Women with a pre-gestational body mass index (BMI) above 30 kg/m2 giving birth by caesarean section are at high risk of surgical wound infection compared with women with a BMI below 30 kg/m2. Incisional Negative Pressure Wound Therapy (iNPWT) is one strategy to reduce the rate of surgical wound...... infection. However, the treatment is relatively costly compared to standard postoperative dressings and thus it was important to consider the rationale for using iNPWT before introducing the treatment in a clinical setting. This thesis assesses the current evidence of whether iNPWT reduces post......-surgical wound complications when applied to closed surgical incisions. The meta-analysis showed that iNPWT appears to reduce the risk of post-surgical wound infection and seroma formation in high-risk wounds compared with standard postoperative dressings in selected surgical procedures. The thesis comprises a...

  15. Air pollution monitoring by negative-ion mass spectrometry

    International Nuclear Information System (INIS)

    Research into the use of negative-ion mass spectrometry for the monitoring of oxygen-containing gases is reported. Electron impact by low-energy electrons of oxyden-containing gases will result in dissociative electron capture forming O-. By introducing into a negative-ion mass spectrometer a mixture of SO2, NO, NO2, CO, CO2 and O2, focussing O- (m/e = 16) onto the collector, and varying the electron energy, a spectrum of peaks is obtained, which are characteristic of the oxygen-containing molecules in the mixture. The results of this research will be the basis of the design of a small negative-ion mass spectrometer system for the monitoring of oxygen-containing gases in air. (author)

  16. Negative ion sources for tandem accelerator

    International Nuclear Information System (INIS)

    Four kinds of negative ion sources (direct extraction Duoplasmatron ion source, radial extraction Penniing ion source, lithium charge exchange ion source and Middleton-type sputter ion source) have been installed in the JAERI tandem accelerator. The ion sources can generate many negative ions ranging from Hydrogen to Uranium with the exception of Ne, Ar, Kr, Xe and Rn. Discussions presented in this report include mechanisms of negative ion formation, electron affinity and stability of negative ions, performance of the ion sources and materials used for negative ion production. Finally, the author will discuss difficult problems to be overcome in order to get any negative ion sufficiently. (author)

  17. 收入不平等对经济增长的负面影响机制——近二十年文献综述%Study on the Negative Impact of Income Inequality to Economic Growth——A Literature Review of the Last Twenty Years

    Institute of Scientific and Technical Information of China (English)

    刘孟飞

    2011-01-01

    In recent years,the domestic and foreign scholars used all kinds of methodologies to research the relationship of income inequality and economic growth.Most conclusion indicated that the income inequality have negative impact upon economic growth,between each other there exists a complex conduction process through several factors,including human capital accumulation mechanism,political and economic decision-making mechanism,social conflicts mechanism,the mechanism of conduction and demand of other mechanisms.Considered together,these researches have deepened our knowledge on the nature relation and influence of income inequality and economic growth.But the conclusion divergence and research method limitations still exist.It is necessary to make more researches for farther understanding.%近年来,国内外学者运用各种方法探讨了收入不平等与经济增长的关系。大部分研究结论显示,收入差距对经济增长存在间接的负面影响,两者之间存在一个多因素的传导过程,包括人力资本积累机制、政治经济决策机制、社会冲突机制、需求传导机制以及其他传导机制。总的来看,这些研究加深了对于两者关系性质和相互影响的认识,但研究结论的分歧和研究方法的局限性仍然存在,有必要对两者关系进行更深入的研究。

  18. Job characteristics, ill health and negative work-home interference in the mining industry

    OpenAIRE

    Gary Oldfield; Karina Mostert

    2007-01-01

    The objective of this research was to test a structural model including job demands, job resources, ill health and negative work-home interference (WHI). Random samples (N = 320) were taken from employees working in the mining industry. The results indicated that job demands and job resources had an impact on ill health, and that ill health was associated with negative WHI. It was also found that job demands had a direct relationship with negative WHI, in addition to the indirect relationship...

  19. Negative Pressure Wound Therapy. Therapy Settings and Biological Effects in Peripheral Wounds

    OpenAIRE

    Borgquist, Ola

    2013-01-01

    Negative pressure wound therapy (NPWT) promotes wound healing through several mechanisms, e.g., altered periwound blood flow, mechanical deformation of the wound edge tissue, and drainage of excess fluid and debris. The general aim of this thesis was to study the impact of different levels of negative pressure, different wound filling materials (foam or gauze), and different ways of applying the negative pressure (continuously, intermittently or variably) on the biological effects of NPWT in ...

  20. The role of multiple negative social relationships in inflammatory cytokine responses to a laboratory stressor

    OpenAIRE

    Sunmi Song; Graham-Engeland, Jennifer E.; Corwin, Elizabeth J; Ceballos, Rachel M.; Taylor, Shelley E.; Teresa Seeman; Laura Cousino Klein

    2015-01-01

    The present study examined the unique impact of perceived negativity in multiple social relationships on endocrine and inflammatory responses to a laboratory stressor. Via hierarchical cluster analysis, those who reported negative social exchanges across relationships with a romantic partner, family, and their closest friend had higher mean IL-6 across time and a greater increase in TNF-α from 15 min to 75 min post stress. Those who reported negative social exchanges across relationships with...

  1. Effects of early negative life events on cognitive functioning and risk for suicide in a college sample

    OpenAIRE

    Yang, Bin

    1995-01-01

    The present study was designed to examine the etiology of suicidal behavior from cognitive and developmental perspectives. Given empirical evidence suggesting links between early negative life events and suicidal behavior, between early negative life events and cognitive factors, and between cognitive factors and suicidal behavior, it was hypothesized that early negative life events may impact individuals' suicidal behavior by affecting these individuals' cognitive functioni...

  2. The Effectiveness of Peer Mediation on Reducing Middle School Violence and Negative Behaviors

    Science.gov (United States)

    Cigainero, Lorraine

    2009-01-01

    The purpose of this study was to examine the impact of peer mediation on reducing violence and negative behaviors in middle school students. Negative behaviors included various ways students disrupt learning and included tardiness, absenteeism and truancy as well as classroom distractions of all forms. Three middle schools all in the same school…

  3. Analysing Users' Satisfaction with E-Learning Using a Negative Critical Incidents Approach

    Science.gov (United States)

    Chen, Nian-Shing; Lin, Kan-Min; Kinshuk

    2008-01-01

    One critical success factor for e-learning is learners' satisfaction with it. This is affected by both positive and negative experiences in a learning process. This paper examines the impact of such critical incidents on learners' satisfaction in e-learning. In particular, frequent occurrence of negative critical incidents has significant…

  4. Biophysical and economic limits to negative CO2 emissions

    OpenAIRE

    Smith, P; Davis, S J; Creutzig, F.; Minx, J.

    2016-01-01

    To have a >50% chance of limiting warming below 2 °C, most recent scenarios from integrated assessment models (IAMs) require large-scale deployment of negative emissions technologies (NETs). These are technologies that result in the net removal of greenhouse gases from the atmosphere. We quantify potential global impacts of the different NETs on various factors (such as land, greenhouse gas emissions, water, albedo, nutrients and energy) to determine the biophysical limits to, and economic co...

  5. Cognitive load has negative after effects on consumer decision making.

    OpenAIRE

    Dewitte, Siegfried; Pandelaere, Mario; Briers, Barbara; Warlop, Luk

    2005-01-01

    Concurrent cognitive load has a devastating effect on consumer decision making. Implicit in the theorizing about cognitive load seems to be that this negative effect disappears when the load is removed. Three experiments explored whether cognitive load produces after-effects and showed that various types of prior cognitive load increase the subsequent impact of easily available information on brand choice (study 1), product similarity ratings (study 2), and the quantity of food consumed in a ...

  6. Acute Effects of Marijuana Smoking on Negative and Positive Affect

    OpenAIRE

    Metrik, Jane; Kahler, Christopher W.; McGeary, John E.; Monti, Peter M.; Rohsenow, Damaris J.

    2011-01-01

    Human studies and animal experiments present a complex and often contradictory picture of the acute impact of marijuana on emotions. The few human studies specifically examining changes in negative affect find either increases or reductions following delta-9-tetrahydrocannabinol (THC) administration. In a 2 × 2, instructional set (told THC vs. told no THC) by drug administration (smoked marijuana with 2.8% THC vs. placebo) between-subjects design, we examined the pharmacologic effect of marij...

  7. Chiral Negative-Index Metamaterials in Terahertz

    CERN Document Server

    Zhang, Shuang; Li, Jensen; Lu, Xinchao; Zhang, Weili; Zhang, Xiang

    2008-01-01

    Negative index metamaterials (NIMs) give rise to unusual and intriguing properties and phenomena, which may lead to important applications such as superlens, subwavelength cavity and slow light devices. However, the negative refractive index in metamaterials normally requires a stringent condition of simultaneously negative permittivity and negative permeability. A new class of negative index metamaterials - chiral NIMs, have been recently proposed. In contrast to the conventional NIMs, chiral NIMs do not require the above condition, thus presenting a very robust route toward negative refraction. Here we present the first experimental demonstration of a chiral metamaterial exhibiting negative refractive index down to n=-5 at terahertz frequencies, with only a single chiral resonance. The strong chirality present in the structure lifts the degeneracy for the two circularly polarized waves and relieves the double negativity requirement. Chiral NIM are predicted to possess intriguing electromagnetic properties t...

  8. Negative dimension in general and asymptotic topology

    OpenAIRE

    Maslov, V. P.

    2006-01-01

    We introduce the notion of negative topological dimension and the notion of weight for the asymptotic topological dimension. Quantizing of spaces of negative dimension is applied to linguistic statistics.

  9. Neutral beam production using negative ions

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, E.B. Jr.

    1978-06-14

    Techniques for producing intense negative ion beams are discussed. These beams are required for intense neutral beam development at energies greater than 150 keV. Handling, acceleration, and stripping of negative ion beams are described.

  10. Visual content of words delays negation.

    Science.gov (United States)

    Orenes, Isabel; Santamaría, Carlos

    2014-11-01

    Many studies have shown the advantage of processing visualizable words over non-visualizables due to the associated image code. The present paper reports the case of negation in which imagery could slow down processing. Negation reverses the truth value of a proposition from false to true or vice versa. Consequently, negation works only on propositions (reversing their truth value) and cannot apply directly to other forms of knowledge representation such as images (although they can be veridical or not). This leads to a paradoxical hypothesis: despite the advantage of visualizable words for general processing, the negation of clauses containing words related to the representation of an image would be more difficult than negation containing non-visualizable words. Two experiments support this hypothesis by showing that sentences with a previously negated visualizable word took longer to be read than sentences with previously negated non-visualizable words. The results suggest that a verbal code is used to process negation. PMID:25463550

  11. Negative-on source applications (invited)

    OpenAIRE

    Ishikawa, J

    2008-01-01

    In this paper heavy negative-ion sources which we developed and their applications for materials science are reviewed. Heavy negative ions can be effectively produced by the ejection of a sputtered atom through the optimally cesiated surface of target with a low work function. Then, enough continuous negative-ion currents for materials-science applications can be obtained. We developed several kinds of sputter-type heavy negative-ion sources such as neutral- and ionized-alkaline metal bombard...

  12. DO NEGATIVE SYMPTOMS INFLUENCE OUTCOME OF DEPRESSION?

    OpenAIRE

    Chaturvedi, Santosh K.; Sarmukkaddam, Sanjeev B.

    1986-01-01

    SUMMARY Thirty four cases of endogenous major depression (RDC) have been studied in order to examine whether negative symptoms influence the outcome of depression, by comparing depressives with and without predominant negative symptoms, and by examining which negative symptoms have high percentage reduction in scores. Patients were rated on Scale for Assessment of Negative Symptoms (SANS) during their inclusion and later during one year followup. Complete recovery was seen in only 41 % of the...

  13. Negative creep in nickel base superalloys

    DEFF Research Database (Denmark)

    Dahl, Kristian Vinter; Hald, John

    Negative creep describes the time dependent contraction of a material as opposed to the elongation seen for a material experiencing normal creep behavior. Negative creep occurs because of solid state transformations that results in lattice contractions. For most applications negative creep will h...

  14. Negative creep in nickel base superalloys

    DEFF Research Database (Denmark)

    Dahl, Kristian Vinter; Hald, John

    2004-01-01

    Negative creep describes the time dependent contraction of a material as opposed to the elongation seen for a material experiencing normal creep behavior. Negative creep occurs because of solid state transformations that results in lattice contractions. For most applications negative creep will h...

  15. Energy flow in negative index materials

    Institute of Scientific and Technical Information of China (English)

    Lorenzo Bolla; Michele Midrio; Carlo G. Someda

    2004-01-01

    From Maxwell's equations, we compute the speed and the direction of propagation of active power refractedfrom air into a negative index material. We prove, both analytically and numerically that the power mayrefract positively even if phase fronts refract negatively. Considerations on the usage of ray optics inproblems involving negative index materials are drawn.

  16. 14 CFR 25.943 - Negative acceleration.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Negative acceleration. 25.943 Section 25... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant General § 25.943 Negative acceleration. No... the negative accelerations within the flight envelopes prescribed in § 25.333. This must be shown...

  17. 14 CFR 23.943 - Negative acceleration.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Negative acceleration. 23.943 Section 23... Negative acceleration. No hazardous malfunction of an engine, an auxiliary power unit approved for use in... the airplane is operated at the negative accelerations within the flight envelopes prescribed in §...

  18. 40 CFR 62.06 - Negative declarations.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Negative declarations. 62.06 Section 62....06 Negative declarations. A State may submit to the Administrator a letter certifying that no designated facilities exist in the State if such is the case. The negative declaration will be in lieu of...

  19. 40 CFR 52.122 - Negative declarations.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Negative declarations. 52.122 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.122 Negative declarations. (a) The following air pollution control districts submitted negative declarations for volatile organic compound...

  20. Negative emotion boosts quality of visual working memory representation.

    Science.gov (United States)

    Xie, Weizhen; Zhang, Weiwei

    2016-08-01

    Negative emotion impacts a variety of cognitive processes, including working memory (WM). The present study investigated whether negative emotion modulated WM capacity (quantity) or resolution (quality), 2 independent limits on WM storage. In Experiment 1, observers tried to remember several colors over 1-s delay and then recalled the color of a randomly picked memory item by clicking a best-matching color on a continuous color wheel. On each trial, before the visual WM task, 1 of 3 emotion conditions (negative, neutral, or positive) was induced by having observers to rate the valence of an International Affective Picture System image. Visual WM under negative emotion showed enhanced resolution compared with neutral and positive conditions, whereas the number of retained representations was comparable across the 3 emotion conditions. These effects were generalized to closed-contour shapes in Experiment 2. To isolate the locus of these effects, Experiment 3 adopted an iconic memory version of the color recall task by eliminating the 1-s retention interval. No significant change in the quantity or quality of iconic memory was observed, suggesting that the resolution effects in the first 2 experiments were critically dependent on the need to retain memory representations over a short period of time. Taken together, these results suggest that negative emotion selectively boosts visual WM quality, supporting the dissociable nature quantitative and qualitative aspects of visual WM representation. (PsycINFO Database Record PMID:27078744

  1. Study on space charge compensation in negative hydrogen ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, A. L.; Chen, J. E. [University of Chinese Academy of Sciences, Beijing 100049 (China); State Key Laboratory of Nuclear Physics and Technology, Institute of Heavy Ion Physics, School of Physics, Peking University, Beijing 100871 (China); Peng, S. X., E-mail: sxpeng@pku.edu.cn; Ren, H. T.; Zhang, T.; Zhang, J. F.; Xu, Y.; Guo, Z. Y. [State Key Laboratory of Nuclear Physics and Technology, Institute of Heavy Ion Physics, School of Physics, Peking University, Beijing 100871 (China)

    2016-02-15

    Negative hydrogen ion beam can be compensated by the trapping of ions into the beam potential. When the beam propagates through a neutral gas, these ions arise due to gas ionization by the beam ions. However, the high neutral gas pressure may cause serious negative hydrogen ion beam loss, while low neutral gas pressure may lead to ion-ion instability and decompensation. To better understand the space charge compensation processes within a negative hydrogen beam, experimental study and numerical simulation were carried out at Peking University (PKU). The simulation code for negative hydrogen ion beam is improved from a 2D particle-in-cell-Monte Carlo collision code which has been successfully applied to H{sup +} beam compensated with Ar gas. Impacts among ions, electrons, and neutral gases in negative hydrogen beam compensation processes are carefully treated. The results of the beam simulations were compared with current and emittance measurements of an H{sup −} beam from a 2.45 GHz microwave driven H{sup −} ion source in PKU. Compensation gas was injected directly into the beam transport region to modify the space charge compensation degree. The experimental results were in good agreement with the simulation results.

  2. Study on space charge compensation in negative hydrogen ion beam

    Science.gov (United States)

    Zhang, A. L.; Peng, S. X.; Ren, H. T.; Zhang, T.; Zhang, J. F.; Xu, Y.; Guo, Z. Y.; Chen, J. E.

    2016-02-01

    Negative hydrogen ion beam can be compensated by the trapping of ions into the beam potential. When the beam propagates through a neutral gas, these ions arise due to gas ionization by the beam ions. However, the high neutral gas pressure may cause serious negative hydrogen ion beam loss, while low neutral gas pressure may lead to ion-ion instability and decompensation. To better understand the space charge compensation processes within a negative hydrogen beam, experimental study and numerical simulation were carried out at Peking University (PKU). The simulation code for negative hydrogen ion beam is improved from a 2D particle-in-cell-Monte Carlo collision code which has been successfully applied to H+ beam compensated with Ar gas. Impacts among ions, electrons, and neutral gases in negative hydrogen beam compensation processes are carefully treated. The results of the beam simulations were compared with current and emittance measurements of an H- beam from a 2.45 GHz microwave driven H- ion source in PKU. Compensation gas was injected directly into the beam transport region to modify the space charge compensation degree. The experimental results were in good agreement with the simulation results.

  3. Issues in the understanding of negative ion extraction for fusion

    Science.gov (United States)

    Boeuf, J. P.; Fubiani, G.; Garrigues, L.

    2016-08-01

    A number of recent papers have been devoted to the modeling of negative ion extraction using particle simulations but the published results are not entirely satisfactory and not fully consistent with experiments. Issues raised by the simulations concern the saturation of the negative ion current emitted from the caesiated plasma grid surface, its distribution along the surface, the shape of the meniscus formed around each grid aperture, the distribution and depth of the potential in the virtual cathode, and the profile of the extracted beamlet. These are important issues since they have direct impact on the properties of the extracted negative ion beam (intensity, brightness, aberration). In this paper we first summarize recently published model results that are unexpected and counter-intuitive since they predict that negative ions are extracted from regions of the grid that are directly exposed to the large extraction voltage (i.e. as in vacuum and without the need for a neutralizing background plasma). We then illustrate, with results from two-dimensional particle-in-cell Monte Carlo collision simulations, some regimes of negative ion extraction that are more consistent with the expected physics.

  4. Study on space charge compensation in negative hydrogen ion beam

    International Nuclear Information System (INIS)

    Negative hydrogen ion beam can be compensated by the trapping of ions into the beam potential. When the beam propagates through a neutral gas, these ions arise due to gas ionization by the beam ions. However, the high neutral gas pressure may cause serious negative hydrogen ion beam loss, while low neutral gas pressure may lead to ion-ion instability and decompensation. To better understand the space charge compensation processes within a negative hydrogen beam, experimental study and numerical simulation were carried out at Peking University (PKU). The simulation code for negative hydrogen ion beam is improved from a 2D particle-in-cell-Monte Carlo collision code which has been successfully applied to H+ beam compensated with Ar gas. Impacts among ions, electrons, and neutral gases in negative hydrogen beam compensation processes are carefully treated. The results of the beam simulations were compared with current and emittance measurements of an H− beam from a 2.45 GHz microwave driven H− ion source in PKU. Compensation gas was injected directly into the beam transport region to modify the space charge compensation degree. The experimental results were in good agreement with the simulation results

  5. Immigration Wage Impacts by Origin

    OpenAIRE

    Bernt Bratsberg; Oddbjørn Raaum; Marianne Røed; Pål Schøne

    2010-01-01

    We estimate the direct partial wage effect for native workers of an immigrant-induced increase in labor supply, using longitudinal records drawn from Norwegian registers and the national skill cell approach of Borjas (2003). Our results show overall negative wage impacts for both men and women. Focusing on differential wage impacts by immigrant origin, we find that immigrant inflows from the neighboring Nordic countries have more negative wage effects than inflows from developing countries. T...

  6. The Impact of Exclusionary Discipline on Students

    Science.gov (United States)

    Ryan, Thomas G.; Goodram, Brian

    2013-01-01

    The impact of exclusionary discipline on students is clear and negative as we report herein. The impacts of exclusionary discipline have been negatively linked to the academic and social development of disciplined students. We argue that this discipline form has been disproportionately used among certain groups, particularly those students of…

  7. Job characteristics, ill health and negative work-home interference in the mining industry

    Directory of Open Access Journals (Sweden)

    Gary Oldfield

    2007-02-01

    Full Text Available The objective of this research was to test a structural model including job demands, job resources, ill health and negative work-home interference (WHI. Random samples (N = 320 were taken from employees working in the mining industry. The results indicated that job demands and job resources had an impact on ill health, and that ill health was associated with negative WHI. It was also found that job demands had a direct relationship with negative WHI, in addition to the indirect relationship through ill health. Job resources were not related not negative WHI.

  8. Soil carbon sequestration and biochar as negative emission technologies.

    Science.gov (United States)

    Smith, Pete

    2016-03-01

    Despite 20 years of effort to curb emissions, greenhouse gas (GHG) emissions grew faster during the 2000s than in the 1990s, which presents a major challenge for meeting the international goal of limiting warming to capture, enhanced weathering, bioenergy with carbon capture and storage and afforestation/deforestation, showed that all NETs have significant limits to implementation, including economic cost, energy requirements, land use, and water use. In this paper, I assess the potential for negative emissions from soil carbon sequestration and biochar addition to land, and also the potential global impacts on land use, water, nutrients, albedo, energy and cost. Results indicate that soil carbon sequestration and biochar have useful negative emission potential (each 0.7 GtCeq. yr(-1) ) and that they potentially have lower impact on land, water use, nutrients, albedo, energy requirement and cost, so have fewer disadvantages than many NETs. Limitations of soil carbon sequestration as a NET centre around issues of sink saturation and reversibility. Biochar could be implemented in combination with bioenergy with carbon capture and storage. Current integrated assessment models do not represent soil carbon sequestration or biochar. Given the negative emission potential of SCS and biochar and their potential advantages compared to other NETs, efforts should be made to include these options within IAMs, so that their potential can be explored further in comparison with other NETs for climate stabilization. PMID:26732128

  9. Avoiding Negative Probabilities in Quantum Mechanics

    CERN Document Server

    Nyambuya, Golden Gadzirayi

    2013-01-01

    As currently understood since its discovery, the bare Klein-Gordon theory consists of negative quantum probabilities which are considered to be physically meaningless if not outright obsolete. Despite this annoying setback, these negative probabilities are what led the great Paul Dirac in 1928 to the esoteric discovery of the Dirac Equation. The Dirac Equation led to one of the greatest advances in our understanding of the physical world. In this reading, we ask the seemingly senseless question, "Do negative probabilities exist in quantum mechanics?" In an effort to answer this question, we arrive at the conclusion that depending on the choice one makes of the quantum probability current, one will obtain negative probabilities. We thus propose a new quantum probability current of the Klein-Gordon theory. This quantum probability current leads directly to positive definite quantum probabilities. Because these negative probabilities are in the bare Klein-Gordon theory, intrinsically a result of negative energie...

  10. Negative staining and Cryo-negative Staining of Macromolecules and Viruses for TEM

    OpenAIRE

    De Carlo, Sacha; Harris, J Robin

    2010-01-01

    In this review we cover the technical background to negative staining of biomolecules and viruses, and then expand upon the different possibilities and limitations. Topics range from conventional air-dry negative staining of samples adsorbed to carbon support films, the variant termed the “negative staining-carbon film” technique and negative staining of samples spread across the holes of holey carbon support films, to a consideration of dynamic/time-dependent negative staining. For each of t...

  11. Negative pressure wound therapy: clinical utility

    OpenAIRE

    Sandoz H

    2015-01-01

    Heidi Sandoz Accelerate CIC, Mile End Hospital, London, UK Abstract: Negative pressure wound therapy (NPWT), also known as topical negative pressure therapy, has been increasingly used in health care for the management of a wide variety of wounds over the last 2–3 decades. It is an advanced therapy that can be helpful to accelerate wound healing in both acute and chronic wounds by delivering negative pressure (suction) to the wound bed. More recent advancements in the application of NP...

  12. Numerical predictions of the negative phase

    OpenAIRE

    Sielicki, P.W.; Rigby, S. E.; Sumelka, W.

    2015-01-01

    The field of blast protective design emerged in the late 1940s and focussed mainly on large scale (nuclear) explosive loading massive structures. In these situations, positive phase effects were seen to dominate and the negative phase could effectively be ignored. Recently, however, the threat has moved to smaller scale explosives and increasingly lightweight structures. Here, the negative phase becomes important, however despite this the negative phase is often overlooked. This research pres...

  13. Negational Fragment of Intuitionistic Control Logic

    OpenAIRE

    Glenszczyk, Anna

    2014-01-01

    We investigate properties of monadic purely negational fragment of Intuitionistic Control Logic (ICL). This logic arises from Intuitionistic Propositional Logic (IPL) by extending language of IPL by additional new constant for falsum. Having two different falsum constants enables to define two forms of negation. We analyse implicational relations between negational monadic formulae and present a poset of non equivalent formulae of this fragment of ICL.

  14. Negative pressure wound therapy: clinical utility

    OpenAIRE

    Sandoz H

    2015-01-01

    Heidi Sandoz Accelerate CIC, Mile End Hospital, London, UK Abstract: Negative pressure wound therapy (NPWT), also known as topical negative pressure therapy, has been increasingly used in health care for the management of a wide variety of wounds over the last 2–3 decades. It is an advanced therapy that can be helpful to accelerate wound healing in both acute and chronic wounds by delivering negative pressure (suction) to the wound bed. More recent advancements in the application o...

  15. Conscientiousness predicts greater recovery from negative emotion

    OpenAIRE

    Javaras, Kristin N.; Schaefer, Stacey M.; van Reekum, Carien M.; Lapate, Regina C.; Greischar, Lawrence L.; Bachuber, David R.; Love, Gale; Ryff, Carol D.; Davidson, Richard J

    2012-01-01

    Greater levels of conscientiousness have been associated with lower levels of negative affect. We focus on one mechanism through which conscientiousness may decrease negative affect: effective emotion regulation, as reflected by greater recovery from negative stimuli. In 273 adults who were 35 - 85 years old, we collected self-report measures of personality including conscientiousness and its self-control facet, followed on average 2 years later by psychophysiological measures of emotional re...

  16. Negative Effective Density in An Acoustic Metamaterial

    OpenAIRE

    Lee, Sam Hyeon; Park, Choon Mahn; Seo, Yong Mun; Wang, Zhi Guo; Kim, Chul Koo

    2008-01-01

    We report theoretical and experimental results for a new type of homogenized acoustic metamaterials with negative effective mass density. We constructed one-dimensional metamaterial, which is a tube with an array of very thin elastic membranes placed inside. This structure exhibited negative effective density in the frequency range from 0 to 735 Hz. The experimental result is in excellent agreement with our theoretical model that predicts negative effective density below a cut-off frequency. ...

  17. Negative Priming in Free Recall Reconsidered

    OpenAIRE

    Hanczakowski, Maciej; Beaman, C. Philip; Jones, Dylan M.

    2015-01-01

    Negative priming in free recall is the finding of impaired memory performance when previously ignored auditory distracters become targets of encoding and retrieval. This negative priming has been attributed to an aftereffect of deploying inhibitory mechanisms that serve to suppress auditory distraction and minimize interference with learning and retrieval of task-relevant information. In 6 experiments, we tested the inhibitory account of the effect of negative priming in free recall against a...

  18. Detection of negative energy: 4-dimensional examples

    International Nuclear Information System (INIS)

    We study the response of switched particle detectors to static negative energy densities and negative energy fluxes. It is demonstrated how the switching leads to excitation even in the vacuum and how negative energy can lead to a suppression of this excitation. We obtain quantum inequalities on the detection similar to those obtained for the energy density by Ford and co-workers and in an 'operational' context by Helfer. We reexamine the question 'Is there a quantum equivalence principle?' in terms of our model. Finally, we briefly address the issue of negative energy and the second law of thermodynamics

  19. Pais-Uhlenbeck Oscillator and Negative Energies

    CERN Document Server

    Pavšič, Matej

    2016-01-01

    We review the occurrence of negative energies in Pais-Uhlenbeck oscillator. We point out that in the absence of interactions negative energies are not problematic, neither in the classical nor in the quantized theory. However, in the presence of interactions that couple positive and negative energy degrees of freedom the system is unstable, unless the potential is bounded from bellow and above. We review some approaches in the literature that attempt to avoid the problem of negative energies in the Pais-Uhlenbeck oscillator.

  20. Double-negative flexural acoustic metamaterial

    International Nuclear Information System (INIS)

    We present an acoustic metamaterial for flexural waves with both negative density and elastic modulus. By means of an analytical lumped-element approach, we introduce a combination of resonant elements on the surface of a plate. Following on from experimental demonstrations and theoretical work, negative density is achieved by introducing elements such as stubs that involve normal-force interactions, whereas negative modulus is achieved by introducing new types of resonant element that involve lateral forces and rotational inertia. Our approach therefore opens the way for the realization of double-negative acoustic meta-plates to control flexural waves. Applications include cloaking and filtering. (paper)

  1. Entanglement negativity after a global quantum quench

    International Nuclear Information System (INIS)

    We study the time evolution of the logarithmic negativity after a global quantum quench. In a 1 + 1-dimensional conformal invariant field theory, we consider the negativity between two intervals which can be either adjacent or disjoint. We show that the negativity follows the quasi-particle interpretation for the spreading of entanglement. We check and generalise our findings with a systematic analysis of the negativity after a quantum quench in the harmonic chain, highlighting two peculiar lattice effects: the late birth and the sudden death of entanglement. (paper)

  2. An advanced negative hydrogen ion source

    Energy Technology Data Exchange (ETDEWEB)

    Goncharov, Alexey A., E-mail: gonchar@iop.kiev.ua; Dobrovolsky, Andrey N.; Goretskii, Victor P. [Institute of Physics National Academy of Science in Ukraine, Kiev 03028 (Ukraine)

    2016-02-15

    The results of investigation of emission productivity of negative particles source with cesiated combined discharge are presented. A cylindrical beam of negative hydrogen ions with density about 2 A/cm{sup 2} in low noise mode on source emission aperture is obtained. The total beam current values are up to 200 mA for negative hydrogen ions and up to 1.5 A for all negative particles with high divergence after source. The source has simple design and can produce stable discharge with low level of oscillation.

  3. Negative emotion impairs conflict-driven executive control

    Directory of Open Access Journals (Sweden)

    SrikanthPadmala

    2011-08-01

    Full Text Available Cognition and emotion interact in important ways to shape ongoing behaviors. In this study, we investigated the interaction between conflict-driven executive control adjustments and emotion during a face-word Stroop-like paradigm. Neutral and negative images were employed to manipulate emotion. We were particularly interested in contrasting two hypotheses of the impact of emotion on conflict adaptation effects. On the one hand, resource accounts of cognitive-emotional interactions predict that behavioral adjustments following incongruent trials would be decreased when participants also have to process a negative stimulus. On the other hand, affect regulation models predict that negative emotion should increase behavioral adjustments. We found that task-irrelevant negative stimuli significantly reduced conflict-driven control effects (i.e., conflict adaptation compared to neutral images. We interpret the findings in terms of shared resources between proactive control mechanisms and emotional processing. Our findings demonstrate that emotion interacts with executive mechanisms responsible for dynamic behavioral adjustments that are tied to environmental demands, a central facet of flexible, goal-directed behavior.

  4. Positive and negative corona discharges in flowing carbon dioxide

    International Nuclear Information System (INIS)

    The effect of the gas flow rate (10-320 cm3 min-1) on the process of ozone formation in both positive and negative corona discharges has been studied using a coaxial cylindrical system of electrodes fed by dry CO2. The source of ozone is electron impact dissociation of carbon dioxide to liberate oxygen atoms and their subsequent formation of oxygen molecules, which may then form ozone by the well-known Chapman mechanism. Small increases in flow rate were found to cause a major increase in the discharge current measured in the negative corona discharge. This effect was found to correspond to observed changes in the ozone concentration within the discharge and is a consequence of dissociative electron attachment to ozone leading to negative ion formation in the discharge. In contrast no direct effect of ozone on the positive corona discharge current was observed. The observed increase in average positive ion mobility in the positive corona is ascribed to the conversion of O2+ ions into more mobile O2+ ions. Considerably higher ozone concentrations (up to 100 ppm) were found in the negative corona discharge. The effect of the geometry of the system was also explored by using three different stainless steel outer electrodes with diameters of 10, 15 and 27 mm. Ozone concentrations were found to decrease significantly with increasing radius of the outer electrode at the same average input energy density

  5. Negative ion formation in lanthanide atoms: Many-body effects

    CERN Document Server

    Felfli, Z; Sokolovski, D

    2016-01-01

    Investigations of low-energy electron-scattering of the lanthanide atoms Eu, Nd, Tb, Tm demonstrate that electron-correlation effects and core polarization are the dominant fundamental many-body effects responsible for the formation of metastable states of negative ions. Ramsauer Townsend minima, shape resonances and binding energies of the resultant anions are identified and extracted from the elastic total cross sections calculated using the complex angular momentum method. The large discrepancy between the recently measured electron affinity of 0.116 and the previously measured value of 1.053 eV for Eu is resolved. Also, the previously measured electron affinities for Nd, Tb and Tm are reconciled and new values are extracted from the calculated total cross sections. The large electron affinities found here for these atoms, should be useful in negative ion nanocatalysis, including methane conversion to methanol without CO2 emission, with significant environmental impact.. The powerful complex angular moment...

  6. Ten Rules for Dealing with Negative Contributions in Social Media

    Directory of Open Access Journals (Sweden)

    Adriana Stránská

    2015-03-01

    Full Text Available Social media is becoming a key part of business communication strategy. Despite all the advantages, social media also poses a threat to business reputation. Dissatisfied customers can reach a large audience and share their negative experiences with others. This paper deals with the impact of social media on the practice of public relations. The goal of the paper is to formulate a set of rules for dealing with negative contributions and generally with crisis communication in social media. It is based on two surveys. Individual interviews with social media experts are the core part of the analysis. They are complemented by questioning of consumers to get deeper insight into complaining behavior via social media. The defined set of rules provides a useful tool for the social media crisis management.

  7. Social Impact Assessment in Europe

    DEFF Research Database (Denmark)

    Larsen, Sanne Vammen; Hansen, Anne Merrild; Lyhne, Ivar;

    2015-01-01

    Social impact assessment (SIA) is applied worldwide to assess social impacts of plans and projects. In Europe, directives on environmental assessment (EA) require attention to social impacts, however, there is a need to investigate the implementation in practise. To this end, we study three Danish...... cases, which are characterised by debates and conflicts on social issues. Analysis of the EA statements shows inclusion of a broad range of social impacts. However, the EAs do not fully match the concerns of the public, and social impacts are not always analysed in depth, mitigation measures are not...... suggested or are postponed and the geographical distribution of impacts assessed is biased towards including negative local impacts. We discuss the scope and handling of social impacts, and possible implications. Based on this, we conclude with the view that EA might do the job of handling social impacts in...

  8. The Negative Binomial Distribution in Quantum Physics

    Science.gov (United States)

    Söderholm, Jonas; Inoue, Shuichiro

    2009-06-01

    We give examples of situations where the negative binomial distribution has appeared in quantum physics since its debut in the work of Planck. Several of its properties are reviewed, and Mandel's Q-parameter is shown to play an interesting role. The photon-pair distributions of squeezed vacuum and squeezed single-photon states are identified as negative binomial.

  9. A Characterization of the Negative Binomial Distribution

    OpenAIRE

    Kolev, Nikolay(Department of Physics, University of Regina, SK S4S 0A2, Canada); Minkova, Leda

    2000-01-01

    Only a few characterizations have been obtained in literatute for the negative binomial distribution (see Johnson et al., Chap. 5, 1992). In this article a characterization of the negative binomial distribution related to random sums is obtained which is motivated by the geometric distribution characterization given by Khalil et al. (1991). An interpretation in terms of an unreliable system is given.

  10. Estimation for entanglement negativity of free fermions

    Science.gov (United States)

    Herzog, Christopher P.; Wang, Yihong

    2016-07-01

    In this letter we study the negativity of one dimensional free fermions. We derive the general form of the {{{Z}}N} symmetric term in moments of the partial transposed (reduced) density matrix, which is an algebraic function of the end points of the system. Such a path integral turns out to be a convenient tool for making estimations for the negativity.

  11. About negative refraction and left handed materials

    OpenAIRE

    Ye, Zhen

    2004-01-01

    Here I present an overview of recent studies of the phenomenon of negative refraction and left-handed materials. I will discuss some basic questions pertinent to the problem. It is pointed out that the current claims of negative refraction and left handed materials are not conclusive. To support our consideration, I will start with the fundamental physics.

  12. Negative Knowledge: Understanding Professional Learning and Expertise

    Science.gov (United States)

    Gartmeier, Martin; Bauer, Johannes; Gruber, Hans; Heid, Helmut

    2008-01-01

    In this paper, we critically analyze how the concept of negative knowledge contributes to the understanding of professionals' expert practice and learning. Negative knowledge is experientially acquired knowledge about what is wrong and what is to be avoided during performance in a given work situation. In terms of its theoretical foundation, the…

  13. The Schrodinger equation and negative energies

    OpenAIRE

    Bruce, S

    2008-01-01

    We present a nonrelativistic wave equation for the electron in (3+1)-dimensions which includes negative-energy eigenstates. We solve this equation for three well-known instances, reobtaining the corresponding Pauli equation (but including negative-energy eigenstates) in each case.

  14. Distress attributed to negative symptoms in schizophrenia

    NARCIS (Netherlands)

    Selten, JP; Wiersma, D; van den Bosch, RJ

    2000-01-01

    The purpose of the study was to examine (1) to which negative symptoms schizophrenia patients attribute distress and (2) whether clinical variables can predict the levels of reported distress. With the help of a research assistant, 86 hospitalized patients completed a self-rating scale for negative

  15. Negative Priming in Free Recall Reconsidered

    Science.gov (United States)

    Hanczakowski, Maciej; Beaman, C. Philip; Jones, Dylan M.

    2016-01-01

    Negative priming in free recall is the finding of impaired memory performance when previously ignored auditory distracters become targets of encoding and retrieval. This negative priming has been attributed to an aftereffect of deploying inhibitory mechanisms that serve to suppress auditory distraction and minimize interference with learning and…

  16. 40 CFR 52.2900 - Negative declaration.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Negative declaration. 52.2900 Section... § 52.2900 Negative declaration. (a) Air Pollution Implementation Plan for the Commonwealth of the Northern Mariana Islands. (1) Letter of December 15, 1982, from the Governor to EPA, which is a...

  17. The entanglement negativity in random spin chains

    CERN Document Server

    Ruggiero, Paola; Calabrese, Pasquale

    2016-01-01

    We investigate the logarithmic negativity in strongly-disordered spin chains in the random-singlet phase. We focus on the spin-1/2 random Heisenberg chain and the random XX chain. We find that for two arbitrary intervals the disorder-averaged negativity and the mutual information are proportional to the number of singlets shared between the two intervals. Using the strong-disorder renormalization group (SDRG), we prove that the negativity of two adjacent intervals grows logarithmically with the intervals length. In particular, the scaling behavior is the same as in conformal field theory, but with a different prefactor. For two disjoint intervals the negativity is given by a universal simple function of the cross ratio, reflecting scale invariance. As a function of the distance of the two intervals, the negativity decays algebraically in contrast with the exponential behavior in clean models. We confirm our predictions using a numerical implementation of the SDRG method. Finally, we also implement DMRG simula...

  18. Negative incidental emotions augment fairness sensitivity.

    Science.gov (United States)

    Liu, Cuizhen; Chai, Jing Wen; Yu, Rongjun

    2016-01-01

    Previous studies have shown that task-unrelated emotions induced incidentally exert carryover effects on individuals' subsequent decisions in financial negotiations. However, the specificity of these emotion effects are not clear. In three experiments, we systematically investigated the role of seven transiently induced basic emotions (disgust, sadness, anger, fear, happiness, surprise and neutral) on rejection of unfair offers using the ultimatum game. We found that all negative emotions (disgust, sadness, anger and fear), but not happiness or surprise, significantly increased rejection rates, suggesting that the effect of incidental negative emotions on fairness is not specific to the type of negative emotion. Our findings highlight the role of fleeting emotions in biasing decision-making processes and suggest that all incidental negative emotions exert similar effects on fairness sensitivity, possibly by potentiating attention towards negative aspects of the situation. PMID:27101931

  19. Universe Models with Negative Bulk Viscosity

    CERN Document Server

    Brevik, Iver

    2013-01-01

    The concept of negative temperatures has occasionally been used in connection with quantum systems. A recent example of this sort is reported in the paper of S. Braun et al. [Science 339,52 (2013)], where an attractively interacting ensemble of ultracold atoms is investigated experimentally and found to correspond to a negative-temperature system since the entropy decreases with increasing energy at the high end of the energy spectrum. As the authors suggest, it would be of interest to investigate whether a suitable generalization of standard cosmological theory could be helpful, in order to elucidate the observed accelerated expansion of the universe usually explained in terms of a positive tensile stress (negative pressure). In the present note we take up this basic idea and investigate a generalization of the standard viscous cosmological theory, not by admitting negative temperatures but instead by letting the bulk viscosity take negative values. Evidently, such an approach breaks standard thermodynamics,...

  20. Health in social impact assessment

    OpenAIRE

    den Broeder, Lea; Vanclay, Frank; Fehr, Rainer; Viliani, Francesca; Nowacki, Julia; Martuzzi, Marco

    2014-01-01

    SIA developed alongside EIA in the early 1970s as a mechanism to consider the social impacts of planned interventions. The early understanding tended to limit the practical application of SIA to the project level, usually within the context of regulatory frameworks, and primarily considered only the direct negative impacts. However, like other types of impact assessment, SIA has evolved over time and has diverged considerably from EIA. Nowadays, SIA has widened its scope to become a “philosop...

  1. How do negative emotions impair self-control? A neural model of negative urgency.

    Science.gov (United States)

    Chester, David S; Lynam, Donald R; Milich, Richard; Powell, David K; Andersen, Anders H; DeWall, C Nathan

    2016-05-15

    Self-control often fails when people experience negative emotions. Negative urgency represents the dispositional tendency to experience such self-control failure in response to negative affect. Neither the neural underpinnings of negative urgency nor the more general phenomenon of self-control failure in response to negative emotions are fully understood. Previous theorizing suggests that an insufficient, inhibitory response from the prefrontal cortex may be the culprit behind such self-control failure. However, we entertained an alternative hypothesis: negative emotions lead to self-control failure because they excessively tax inhibitory regions of the prefrontal cortex. Using fMRI, we compared the neural activity of people high in negative urgency with controls on an emotional, inhibitory Go/No-Go task. While experiencing negative (but not positive or neutral) emotions, participants high in negative urgency showed greater recruitment of inhibitory brain regions than controls. Suggesting a compensatory function, inhibitory accuracy among participants high in negative urgency was associated with greater prefrontal recruitment. Greater activity in the anterior insula on negatively-valenced, inhibitory trials predicted greater substance abuse one month and one year after the MRI scan among individuals high in negative urgency. These results suggest that, among people whose negative emotions often lead to self-control failure, excessive reactivity of the brain's regulatory resources may be the culprit. PMID:26892861

  2. Biophysical and economic limits to negative CO2 emissions

    Science.gov (United States)

    Smith, Pete; Davis, Steven J.; Creutzig, Felix; Fuss, Sabine; Minx, Jan; Gabrielle, Benoit; Kato, Etsushi; Jackson, Robert B.; Cowie, Annette; Kriegler, Elmar; van Vuuren, Detlef P.; Rogelj, Joeri; Ciais, Philippe; Milne, Jennifer; Canadell, Josep G.; McCollum, David; Peters, Glen; Andrew, Robbie; Krey, Volker; Shrestha, Gyami; Friedlingstein, Pierre; Gasser, Thomas; Grübler, Arnulf; Heidug, Wolfgang K.; Jonas, Matthias; Jones, Chris D.; Kraxner, Florian; Littleton, Emma; Lowe, Jason; Moreira, José Roberto; Nakicenovic, Nebojsa; Obersteiner, Michael; Patwardhan, Anand; Rogner, Mathis; Rubin, Ed; Sharifi, Ayyoob; Torvanger, Asbjørn; Yamagata, Yoshiki; Edmonds, Jae; Yongsung, Cho

    2016-01-01

    To have a >50% chance of limiting warming below 2 °C, most recent scenarios from integrated assessment models (IAMs) require large-scale deployment of negative emissions technologies (NETs). These are technologies that result in the net removal of greenhouse gases from the atmosphere. We quantify potential global impacts of the different NETs on various factors (such as land, greenhouse gas emissions, water, albedo, nutrients and energy) to determine the biophysical limits to, and economic costs of, their widespread application. Resource implications vary between technologies and need to be satisfactorily addressed if NETs are to have a significant role in achieving climate goals.

  3. On the mechanism of branching in negative ionization fronts

    CERN Document Server

    Arrayas, M; Trueba, J L

    2005-01-01

    We explain a mechanism for branching of a planar negative front. Branching occurs as the result of a balance between the destabilizing effect of impact ionization and the stabilizing effect of electron diffusion on ionization fronts. The dispersion relation for transversal perturbation is obtained analytically and reads: $s = |k|/[2 (1 + |k|)] - D |k|^2$, where $D$, which is assumed to be small, is the ratio between the electron diffusion coefficient and the intensity of the externally imposed electric field. We estimate the spacing $\\lambda$ between streamers in a planar discharge and deduce a scaling law $\\lambda \\sim D^{1/3}$.

  4. Negated bio-events: analysis and identification

    Directory of Open Access Journals (Sweden)

    Nawaz Raheel

    2013-01-01

    Full Text Available Abstract Background Negation occurs frequently in scientific literature, especially in biomedical literature. It has previously been reported that around 13% of sentences found in biomedical research articles contain negation. Historically, the main motivation for identifying negated events has been to ensure their exclusion from lists of extracted interactions. However, recently, there has been a growing interest in negative results, which has resulted in negation detection being identified as a key challenge in biomedical relation extraction. In this article, we focus on the problem of identifying negated bio-events, given gold standard event annotations. Results We have conducted a detailed analysis of three open access bio-event corpora containing negation information (i.e., GENIA Event, BioInfer and BioNLP’09 ST, and have identified the main types of negated bio-events. We have analysed the key aspects of a machine learning solution to the problem of detecting negated events, including selection of negation cues, feature engineering and the choice of learning algorithm. Combining the best solutions for each aspect of the problem, we propose a novel framework for the identification of negated bio-events. We have evaluated our system on each of the three open access corpora mentioned above. The performance of the system significantly surpasses the best results previously reported on the BioNLP’09 ST corpus, and achieves even better results on the GENIA Event and BioInfer corpora, both of which contain more varied and complex events. Conclusions Recently, in the field of biomedical text mining, the development and enhancement of event-based systems has received significant interest. The ability to identify negated events is a key performance element for these systems. We have conducted the first detailed study on the analysis and identification of negated bio-events. Our proposed framework can be integrated with state-of-the-art event

  5. Negative HPV screening test predicts low cervical cancer risk better than negative Pap test

    Science.gov (United States)

    Based on a study that included more than 1 million women, investigators at NCI have determined that a negative test for HPV infection compared to a negative Pap test provides greater safety, or assurance, against future risk of cervical cancer.

  6. Carbon Farming as a Carbon Negative Technology

    Science.gov (United States)

    Anderson, C.; Laird, D.; Hayes, D. J.

    2015-12-01

    Carbon farms have a pivotal role in national and international efforts to mitigate and adapt to climate change. A carbon farm in its broadest sense is one that reduces greenhouse gas (GHG) emissions or captures and holds carbon in vegetation and soils. Their capacity to remove carbon from the air and store it safely and permanently, while providing additional human and ecosystem benefits, means they could contribute significantly to national efforts to stabilize or reduce GHGs. We examine carbon farms in the context of corn and soybean production agriculture. We illustrate, using Iowa data but with relevance across United States corn and soybean production, the potential for carbon farms to reduce human GHG emissions and sequester carbon permanently at a rate that has meaningful impact on global greenhouse gas concentration. Carbon has been viewed as a next generation cash crop in Iowa for over a decade. The carbon farm perspective, however, goes beyond carbon as cash crop to make carbon the center of an entire farm enterprise. The transformation is possible through slight adjustment crop practices mixed with advances in technology to sequester carbon through biochar. We examine carbon balance of Iowa agriculture given only the combination of slight reduction in fertilizer and sequestration by biochar. We find the following. Iowa carbon farms could turn Iowa agriculture into a carbon sink. The estimated range of GHG reduction by statewide implementation of carbon farms is 19.46 to 90.27 MMt CO2-equivalent (CO2-e), while the current agricultural CO2-e emission estimate is 35.38 MMt CO2-e. Iowa carbon farm GHG reduction would exceed Iowa GHG reduction by wind energy (8.7 MMt CO2-e) and could exceed combined reductions from wind energy and corn grain ethanol (10.7 MMt CO2-e; 19.4 MMt CO2-e combined). In fact, Iowa carbon farms alone could exceed GHG reduction from national corn grain ethanol production (39.6 MMt CO2-e). A carbon price accessible to agricultural

  7. Richard Gale and the Problem of Negation

    Directory of Open Access Journals (Sweden)

    Adam Bastek

    2015-01-01

    Full Text Available There is still no agreement as to the way of interpreting negative statements and the ontological status of negative facts or events. Following W. V. Quine (On What There Is, some philosophers claim that world becomes overcrowded. It becomes overcrowded because positive events (or states of affairs carry on their backs an infinite number of negative phantoms (quasi- entities. For instance, my being here now requires my not being elsewhere. As we know, in his works Quine developed a minimalistic vision of ontology (Quine’s taste for desert landscapes related to Ockham’s razor. On the other hand, every true proposition (positive or negative corresponds with an event – there must be a negative event. Otherwise we will find it difficult to express what it is that corresponds to a negative statement. This point of view was temporarily presented by B. Russell (Philosophy of Logical Atomism. Gale (On What There Isn’t examines the arguments for and against negative facts and events. The purpose of this paper is to present Gale’s inquiry into negatives and its ontological consequences. The conclusion of Gale’s investigations is as follows: what exists in the world is positive and the world is fully describable in positive statements. He argues along Kantian lines with British accent: it is meaningful to say that some objects are non-existent but it is meaningless to apply negation to the universe as a whole. While he argues along Kantian lines with British accent, I suggest solution with Polish accent (S. Leśniewski: it is contradictory to say that some objects are nonexistent.

  8. On Negative Yes/No Questions

    OpenAIRE

    Romero, Maribel; Han, Chung-Hye

    2004-01-01

    Preposed negation yes/no (yn)-questions like 'Doesn't John drink?' necessarily carry the implicature that the speaker thinks John drinks, whereas non-preposed negation yn-questions like 'Does John not drink?' do not necessarily trigger this implicature. Furthermore, preposed negation yn-questions have a reading "double-checking" pand a reading "double-checking"≠p, as in 'Isn't Jane coming too?' and in 'Isn't Jane coming either?' respectively. We present other yn-questions that raise parallel ...

  9. Negative temperatures and the definition of entropy

    Science.gov (United States)

    Swendsen, Robert H.; Wang, Jian-Sheng

    2016-07-01

    The concept of negative temperature has recently received renewed interest in the context of debates about the correct definition of the thermodynamic entropy in statistical mechanics. Several researchers have identified the thermodynamic entropy exclusively with the "volume entropy" suggested by Gibbs, and have further concluded that by this definition, negative temperatures violate the principles of thermodynamics. We disagree with these conclusions. We demonstrate that volume entropy is inconsistent with the postulates of thermodynamics for systems with non-monotonic energy densities, while a definition of entropy based on the probability distributions of macroscopic variables does satisfy the postulates of thermodynamics. Our results confirm that negative temperature is a valid extension of thermodynamics.

  10. Critique of Optical Negative Refraction Superlensing

    CERN Document Server

    Christou, George

    2010-01-01

    Has the ten-year old quest for the optical superlens, based on Veselago's hypothesis of negative refraction, been a chimera? We argue that Pendry's alternative prescription of the silver superlens is nothing more than an application of the natural phenomenon of surface plasmon resonance that occurs in the noble metal films. This phenomenon does not predict the reality of Veselago's negative refractive index materials. We give a simple explanation of how this resonance achieves a field intensity enhancement at the interface of silver and air without involving the concept of negative refraction.

  11. Entanglement negativity, Holography and Black holes

    CERN Document Server

    Chaturvedi, Pankaj; Sengupta, Gautam

    2016-01-01

    We conjecture a holographic prescription to compute the entanglement negativity for finite temperature conformal field theories in arbitrary dimensions that leads to the distilled pure quantum entanglement at all temperatures. Our prescription exactly reproduces the entanglement negativity for 1+1 dimensional conformal field theories at finite temperatures dual to bulk Euclidean BTZ black holes. A similar entanglement distillation is also observed for the entanglement negativity of conformal field theories dual to AdS-Schwarzschild black holes in higher dimensions illustrating the universality of our conjecture.

  12. Some dosimetry problems in negative pion radiotherapy

    CERN Document Server

    Baarli, Johan

    1973-01-01

    Momentum beams of negative pions are considered for radiotherapy. It is shown that the measurement of dose in this respect presents problems which are different from those encountered when using the more usual type of radiation. This difference arises principally from the nuclear interaction processes produced when the negative pion comes to rest. These processes, which are superimposed on the Bragg peak of the beam, produce a complex mixture of charged particles together with a beam contamination of muons and electrons. Some experimental studies of depth dose distributions, dose estimates, and other parameters to be considered for radiotherapy of cancer with beams of negative pions are discussed.

  13. Measuring positive and negative occupational states at work: A structural and differential item functioning analysis

    Directory of Open Access Journals (Sweden)

    Marie Barbier

    2012-04-01

    Full Text Available This article reports on the structural validation of the Positive and Negative Occupational States Inventory, which measures positive and negative states at work. The first aim was to check for the impact of item wording. The second aim was to check for interactions between items and gender or age. More than 31,000 data collected in 63 Belgian and French companies were used. Results of structural equation show that meaning better represents the tool structure than wording, at least for the negative occupational state. Results of differential item functioning analyses show that gender and age have no impact on workers' answers. It is concluded that future studies should check for the impact of initial NOSI and POSI levels. Future studies should also examine reciprocal relationships between working conditions on the one hand and NOSI and POSI on the other.

  14. Moderators of Post-Binge Eating Negative Emotion in Eating Disorders

    OpenAIRE

    De Young, Kyle P.; Lavender, Jason M.; Wonderlich, Stephen A.; Crosby, Ross D; Engel, Scott G.; Mitchell, James E; Crow, Scott; Peterson, Carol B.; le Grange, Daniel

    2012-01-01

    The purpose of this study was to test the impact of two variables on post-binge eating negative emotion in a combined sample of women with anorexia nervosa (AN; n = 47) and bulimia nervosa (BN; n = 121). Participants completed two weeks of an ecological momentary assessment protocol during which they provided multiple daily ratings of overall negative affect and guilt and reported eating disorder behaviors including binge eating and self-induced vomiting. The results indicate that both overal...

  15. Negatívne sociálne javy na pracovisku

    OpenAIRE

    Budinská, Dagmara

    2013-01-01

    The bachelor thesis deals with conflicts, mobbing, bossing, staffing,sexual harassment and racism in the workplace. The thesis consists of two parts. The first one, theoretical part, explains and clarifies these negative social phenomenons. Its task is to provide comprehensive information concerning the causes, discourses, stages and impact of negative social phenomenons on the individual and organization. In the second part, practical one, there is analysis and summary of survey that has bee...

  16. Children’s neural response to contrast-negated faces is species-specific

    OpenAIRE

    Balas, Benjamin; Stevenson, Kate

    2013-01-01

    Face recognition abilities develop dramatically during the first year of life, but comparatively little is known about the nature of face-specific perceptual development in early childhood. Face-specific effects of image appearance on recognition, including face inversion and contrast negation, are a useful means of understanding the functional properties of face perception developmentally. Here, we examined the generality of the impact of contrast-negation on face perception in early childho...

  17. Contingent negative variation of mood disorder patients

    Institute of Scientific and Technical Information of China (English)

    Yingzhi Lu; Wenbin Zong; Qingtao Ren; Jinyu Pu; Jun Chen; Juan Li; Xingshi Chen; Yong Wang

    2011-01-01

    Studies on brain-evoked potential and contingent negative variation (CNV) in mood disorder remain controversial. To date, no CNV difference between unipolar and bipolar depression has been reported. Brain-evoked potentials were measured in the present study to analyze CNV in three subtypes of mood disorder (mania, unipolar depression, and bipolar depression), and these results were compared with normal controls. In the mania group, CNV amplitude B was greater than in controls, and the depression group exhibited lower CNV amplitude B and smaller A-S'2 area, and prolonged post-imperative negative variation latency. The CNV comparison between unipolar and bipolar depression found that the prolonged post-imperative negative variation latency was only in unipolar depression. These results suggest that prolonged post-imperative negative variation latency is a characteristic of unipolar depression, and CNV amplitude change is a state characteristic of mood disorder patients.

  18. Unrevealing culture-negative severe sepsis

    OpenAIRE

    de Prost, Nicolas; Razazi, Keyvan; Brun-Buisson, Christian

    2013-01-01

    Sepsis involves a wide array of sources and microorganisms, only a fraction of which are microbiologically documented. Culture-negative sepsis poses special diagnostic challenges to both clinicians and microbiologists and further questions the validity of sepsis definitions.

  19. Negation of the Self in Wuthering Heights

    Institute of Scientific and Technical Information of China (English)

    李敏

    2015-01-01

    Emily Bronte created one of the greatest novels in19th British literary history---Wuthering Heights.Through this works,the writers tries to severely criticize the feature in western civilization:negation of the self.

  20. Surfaces of a Constant Negative Curvature

    Directory of Open Access Journals (Sweden)

    G. M. Gharib

    2012-01-01

    Full Text Available I study the geometric notion of a differential system describing surfaces of a constant negative curvature and describe a family of pseudospherical surfaces for the nonlinear partial differential equations with constant Gaussian curvature .

  1. Cannabis use, schizotypy, and negative priming.

    Science.gov (United States)

    Albertella, Lucy; Le Pelley, Mike E; Copeland, Jan

    2015-08-30

    The present study examined the effects of frequency of cannabis use, schizotypy, and age on cognitive control, as measured using a location-based negative priming task in a sample of 124 Australians aged 15-24 who had ever used cannabis. This study found that the schizotypy dimension of Impulsive Nonconformity had a significant effect on negative priming such that participants with higher scores on this dimension showed reduced negative priming. Also, higher levels of psychological distress were associated with greater negative priming. Finally, there was a significant age by cannabis use interaction indicating that younger, frequent users of cannabis may be more susceptible to its effects on cognitive control and perhaps at greater risk of developing a disorder on the psychosis dimension. PMID:26154815

  2. Negative ion formation processes: A general review

    International Nuclear Information System (INIS)

    The principal negative ion formation processes will be briefly reviewed. Primary emphasis will be placed on the more efficient and universal processes of charge transfer and secondary ion formation through non-thermodynamic surface ionization. 86 refs., 20 figs

  3. Simplifying Negative Goals Using Typed Existence Properties

    CERN Document Server

    Lu, Lunjin

    2010-01-01

    A method for extracting positive information from negative goals is proposed. It makes use of typed existence properties between arguments of a predicate to rewrite negative goals in a logic program. A typed existence property is a generalization of functional dependencies in that an input value maps to a fixed number of output values. Types are used to specify the domains of the input and output values. An implementation of the simplification method is presented and its complexity is analyzed. A key algorithm of the implementation checks if an atom in a negative goal can be extracted using a given typed existence property. A digraph links an atom to the quantified variables occurring in the atom and is used to quickly retrieve atoms in the negative goal that may become extractable after some other atom is extracted.

  4. Negation of the Self in Wuthering Heights

    Institute of Scientific and Technical Information of China (English)

    李敏

    2015-01-01

    Emily Bronte created one of the greatest novels in 19th British literary history---Wuthering Heights.Through this works,the writers tries to severely criticize the feature in western civilization: negation of the self.

  5. Philadelphia-negative classical myeloproliferative neoplasms

    DEFF Research Database (Denmark)

    Barbui, T.; Barosi, G.; Birgegard, G.;

    2011-01-01

    We present a review of critical concepts and produce recommendations on the management of Philadelphia-negative classical myeloproliferative neoplasms, including monitoring, response definition, first- and second-line therapy, and therapy for special issues. Key questions were selected according...

  6. A model for negative ion extraction and comparison of negative ion optics calculations to experimental results

    International Nuclear Information System (INIS)

    Negative ion extraction is described by a model which includes electron diffusion across transverse magnetic fields in the sheath. This model allows a 2-Dimensional approximation of the problem to be made. It is used to introduce electron space charge effects in a 2-D particle trajectory code, designed for negative ion optics calculations. Another physical effect, the stripping of negative ions on gas, has also been included in our model; it is found to play an important role in negative ion optics. The comparison with three sets of experimental data from very different negative ion accelerators, show that our model is capable of accurate predictions

  7. A model for negative ion extraction and comparison of negative ion optics calculations to experimental results

    International Nuclear Information System (INIS)

    Negative ion extraction is described by a model which includes electron diffusion across transverse magnetic fields in the sheath. This model allows a 2-Dimensional approximation of the problem. It is used to introduce electron space charge effects in a 2-D particle trajectory code, designed for negative ion optics calculations. Another physical effect, the stripping of negative ions on neutral gas atoms, has also been included in our model; it is found to play an important role in negative ion optics. The comparison with three sets of experimental data from very different negative ion accelerators, show that our model is able of accurate predictions

  8. Critique of Optical Negative Refraction Superlensing

    OpenAIRE

    Christou, George; Mias, Christos

    2010-01-01

    Has the ten-year old quest for the optical superlens, based on Veselago's hypothesis of negative refraction, been a chimera? We argue that Pendry's alternative prescription of the silver superlens is nothing more than an application of the natural phenomenon of surface plasmon resonance that occurs in the noble metal films. This phenomenon does not predict the reality of Veselago's negative refractive index materials. We give a simple explanation of how this resonance achieves a field intensi...

  9. Classical gravity does not refract negatively.

    Science.gov (United States)

    McCall, Martin W

    2007-03-01

    We appraise recent claims that classical gravitation can induce negative refraction of electromagnetic radiation in vacuum. By recasting the previous literature in covariant notation, we show that the criterion used hitherto for determining negative refraction in vacuum is inappropriate, and can even be satisfied by parametrized transformations in Minkowski spacetime. Using instead a covariantly acceptable definition, we find that in classical vacuum the power flux of a plane electromagnetic wave points in the direction of phase advance. PMID:17359145

  10. Nonparametric Bayesian Negative Binomial Factor Analysis

    OpenAIRE

    Zhou, Mingyuan

    2016-01-01

    A common approach to analyze an attribute-instance count matrix, an element of which represents how many times an attribute appears in an instance, is to factorize it under the Poisson likelihood. We show its limitation in capturing the tendency for an attribute present in an instance to both repeat itself and excite related ones. To address this limitation, we construct negative binomial factor analysis (NBFA) to factorize the matrix under the negative binomial likelihood, and relate it to a...

  11. Negative Binomial States of Quantized Radiation Fields

    OpenAIRE

    Fu, Hong-Chen; Sasaki, Ryu

    1996-01-01

    We introduce the negative binomial states with negative binomial distribution as their photon number distribution. They reduce to the ordinary coherent states and Susskind-Glogower phase states in different limits. The ladder and displacement operator formalisms are found and they are essentially the Perelomov's su(1,1) coherent states via its Holstein-Primakoff realisation. These states exhibit strong squeezing effect and they obey the super-Poissonian statistics. A method to generate these ...

  12. Revisiting the Gram-Negative Lipoprotein Paradigm

    OpenAIRE

    LoVullo, Eric D.; Wright, Lori F.; Isabella, Vincent; Huntley, Jason F.; Pavelka, Martin S.

    2015-01-01

    The processing of lipoproteins (Lpps) in Gram-negative bacteria is generally considered an essential pathway. Mature lipoproteins in these bacteria are triacylated, with the final fatty acid addition performed by Lnt, an apolipoprotein N-acyltransferase. The mature lipoproteins are then sorted by the Lol system, with most Lpps inserted into the outer membrane (OM). We demonstrate here that the lnt gene is not essential to the Gram-negative pathogen Francisella tularensis subsp. tularensis str...

  13. Avoiding Negative Probabilities in Quantum Mechanics

    OpenAIRE

    2013-01-01

    As currently understood since its discovery, the bare Klein-Gordon theory consists of negative quantum probabilities which are considered to be physically meaningless if not outright obsolete. Despite this annoying setback, these negative probabilities are what led the great Paul Dirac in 1928 to the esoteric discovery of the Dirac Equation. The Dirac Equation led to one of the greatest advances in our understanding of the physical world. In this reading, we ask the seemingly senseless questi...

  14. Ruminative Self-Focus and Negative Affect

    OpenAIRE

    Moberly, Nicholas J.; Watkins, Edward R.

    2008-01-01

    The authors conducted an experience sampling study to investigate the relationship between momentary ruminative self-focus and negative affect. Ninety-three adults recorded these variables at quasi-random intervals 8 times daily for 1 week. Scores on questionnaire measures of dispositional rumination were associated with mean levels of momentary ruminative self-focus over the experience sampling week. Concurrently, momentary ruminative self-focus was positively associated with negative affect...

  15. Negative ion formation and neutralization processes, (1)

    International Nuclear Information System (INIS)

    This review has been made preliminary for the purpose of contribute to the plasma heating by ''negative ion based neutral beam injection'' in the magnetic confinement fusion reactor. A compilation includes the survey of the general processes of negative ion formation, the data of the cross section of H- ion formation and the neutralization of H- ion, and some of new processes of H- ion formation. The data of cross section are mainly experimental, but partly include the results of theoretical calculation. (author)

  16. Finite Metric Spaces of Strictly Negative Type

    DEFF Research Database (Denmark)

    Hjorth, Poul; Lisonek, P.; Markvorsen, Steen; Thomassen, Carsten

    We prove that, if a finite metric space is of strictly negative type, then its transfinite diameter is uniquely realized by the infinite extender (load vector). Finite metric spaces that have this property include all spaces on two, three, or four points, all trees, and all finite subspaces of Eu...... by Kelly, we conjecture that all finite subspaces of hyperbolic spaces are hypermetric and regular, and hence of strictly negative type. (C) 1998 Elsevier Science Inc....

  17. Negative Binomial States of Quantized Radiation Fields

    CERN Document Server

    Fu, H C; Fu, Hong-Chen; Sasaki, Ryu

    1996-01-01

    We introduce the negative binomial states with negative binomial distribution as their photon number distribution. They reduce to the ordinary coherent states and Susskind-Glogower phase states in different limits. The ladder and displacement operator formalisms are found and they are essentially the Perelomov's su(1,1) coherent states via its Holstein-Primakoff realisation. These states exhibit strong squeezing effect and they obey the super-Poissonian statistics. A method to generate these states is proposed.

  18. Methodological Issues in Negative Symptom Trials

    OpenAIRE

    Marder, Stephen R.; Daniel, David G; Alphs, Larry; Awad, A George; Richard S E Keefe

    2011-01-01

    Individuals from academia, the pharmaceutical industry, and the US Food and Drug Administration used a workshop format to discuss important methodological issues in the design of trials of pharmacological agents for improving negative symptoms in schizophrenia. The issues addressed included the need for a coprimary functional measure for registration trials; the characteristics of individuals who should enter negative symptom trials; the optimal duration for a proof-of-concept or registration...

  19. Active electroacoustic resonators with negative acoustic properties

    OpenAIRE

    Lissek, Hervé; Boulandet, Romain

    2012-01-01

    Acoustic metamaterials constitute a new class of acoustic structures, composed of periodic arrangements of engineered unit-cells, that exhibit macroscopic acoustic properties not readily available in nature. These properties can either be a negative mass density or a negative bulk modulus. However, these artificial behaviours derive from the engineered arrangement of the unit-cells, which do not present individual ''meta-properties'', rather than from their intrinsic nature. It is although po...

  20. [Depressive symptoms and negative symptoms during schizophrenia].

    Science.gov (United States)

    Dollfus, S; Langlois, S; Assouly-Besse, F; Petit, M

    1995-06-01

    Taking into account the wellknown frequency of depressive and extrapyramidal symptoms in schizophrenia and the rare studies about their evolution, several questions can be raised: How do these different symptoms move? Are there specific characters of each of them? First, stability of negative symptoms evaluated by the Scale for the Assessment of Negative Symptoms (SANS) was studied among 57 schizophrenic patients at admission and at discharge. The course of negative symptoms was compared to that of depressive MADRS (Montgomery et Asberg Depression Rating Scale) and akinetic symptoms (Extrapyramidal Symptom Rating Scale). All the subscores of the SANS decreased significantly but 4 items belonging to the affective flattening subscale and one item belonging to the alogia subscale did not vary significantly, showing the necessity of taking into account the individual items of the SANS rather than the subscale scores to evaluate the course of negative symptoms. Changes in all the SANS subscores except the alogia and anhedonia subscores were associated with variations in scores of other scales. Correlations between the changes of negative symptoms and the changes of depressive symptoms showed the necessity to do more specific scales, for example, scales for depression in schizophrenia. Langlois-Théry et al. (1994) evaluated among 53 schizophrenic patients stabilized with neuroleptic treatment, depressive symptomatology with Echelle de Ralentissement Dépressif (ERD, Widlöcher, 1983) and MADRS, negative symptomatology (Positive and Negative Syndrome Scale) and akinesia (ESRS), to determinate whether ERD composed of 3 subscores (motor, ideic and subjective) could be able to evaluate the depressive symptomatology, independently of the measures of negative and akinetic symptomatology.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7628337

  1. Homologous Recombination in Negative Sense RNA Viruses

    OpenAIRE

    Michael Worobey; Guan-Zhu Han

    2011-01-01

    Recombination is an important process that influences biological evolution at many different levels. More and more homologous recombination events have been reported among negative sense RNA viruses recently. While sporadic authentic examples indicate that homologous recombination does occur, recombination seems to be generally rare or even absent in most negative sense RNA viruses, and most of the homologous recombination events reported in the literature were likely generated artificially d...

  2. Negative Generalization and Symptoms of Anxiety Disorders

    OpenAIRE

    Fulford, Daniel; Rosen, Rebecca K.; Johnson, Sheri L; Carver, Charles S.

    2012-01-01

    The tendency to generalize from a single failure to one's entire self-worth is an important correlate and predictor of depression. Despite conceptual overlap between cognitive biases in anxiety and depression, little research has examined whether negative generalization relates to anxiety symptoms. We examined associations of negative generalization with symptoms of several anxiety disorders, above and beyond its association with lifetime symptoms of depression, among 248 undergraduates. Afte...

  3. Goffman, Parsons, and the Negational Self

    OpenAIRE

    James J. Chriss

    2015-01-01

    Erving Goffman’s emphasis on impression management in everyday life means that for the most part persons offer only partial or incomplete glimpses of themselves. Indeed, under specifiable conditions self-presentations may take the form of a negational self. If negational selves exist at the person or individual level, then they must also exist at the collective level (that is, if we are to take seriously such notions as the social mind, collective representations, or even culture). Understand...

  4. [Pneumocystis pneumonia in HIV-negative adults].

    Science.gov (United States)

    Rouyer, M; Stoclin, A; Blanc, F-X

    2015-12-01

    In HIV-negative adults, Pneumocystis jirovecii pneumonia can be observed when immunodeficiency is present, especially in case of drug-induced immune suppression (steroids, chemotherapy, transplantation). Clinical, radiological, and biological presentations are different in HIV-positive and HIV-negative individuals with different immunodeficiency profiles. In HIV-negative patients, dyspnea occurs more quickly (median duration of 5 days to get a diagnosis), diagnosis is more difficult because of less Pneumocystis in bronchoalveolar lavage, and mortality is higher than in HIV-positive individuals. Lung CT-scan typically shows diffuse ground glass opacities, but peri-bronchovascular condensations or ground glass opacities clearly limited by interlobular septa can also be observed. Lymphopenia is common but CD4+ T-cells count is rarely performed. HIV-negative patients with Pneumocystis pneumonia are co-infected with bacteria, viruses or fungi in about 30% cases. Bronchoalveolar lavage is often more neutrophilic than in HIV-positive individuals. PCR and β-D-glucan have good sensitivity but poor specificity to diagnose Pneumocystis pneumonia. Trimethoprim-sulfamethoxazole remains the first choice of treatment. Duration is 14 days in HIV-negative patients whereas it is typically of 21 days in HIV-positive individuals. Adjunctive corticosteroids are of beneficial effect in HIV-positive adult patients with substantial hypoxaemia but are not recommended in HIV-negative patients, as they could be deleterious in some individuals. PMID:26572261

  5. Negative capacitance in multidomain ferroelectric superlattices

    Science.gov (United States)

    Zubko, Pavlo; Wojdeł, Jacek C.; Hadjimichael, Marios; Fernandez-Pena, Stéphanie; Sené, Anaïs; Luk’Yanchuk, Igor; Triscone, Jean-Marc; Íñiguez, Jorge

    2016-06-01

    The stability of spontaneous electrical polarization in ferroelectrics is fundamental to many of their current applications, which range from the simple electric cigarette lighter to non-volatile random access memories. Research on nanoscale ferroelectrics reveals that their behaviour is profoundly different from that in bulk ferroelectrics, which could lead to new phenomena with potential for future devices. As ferroelectrics become thinner, maintaining a stable polarization becomes increasingly challenging. On the other hand, intentionally destabilizing this polarization can cause the effective electric permittivity of a ferroelectric to become negative, enabling it to behave as a negative capacitance when integrated in a heterostructure. Negative capacitance has been proposed as a way of overcoming fundamental limitations on the power consumption of field-effect transistors. However, experimental demonstrations of this phenomenon remain contentious. The prevalent interpretations based on homogeneous polarization models are difficult to reconcile with the expected strong tendency for domain formation, but the effect of domains on negative capacitance has received little attention. Here we report negative capacitance in a model system of multidomain ferroelectric–dielectric superlattices across a wide range of temperatures, in both the ferroelectric and paraelectric phases. Using a phenomenological model, we show that domain-wall motion not only gives rise to negative permittivity, but can also enhance, rather than limit, its temperature range. Our first-principles-based atomistic simulations provide detailed microscopic insight into the origin of this phenomenon, identifying the dominant contribution of near-interface layers and paving the way for its future exploitation.

  6. Negative brain scintigrams in brain tumors

    International Nuclear Information System (INIS)

    With 53 histologically verified and 2 histologically not identified brain tumors, that showed a negative scintigram, it was tried to find reasons for the wrong and negative dropout of these scintigrams. The electroencephalograms and angiograms, that were made simultaneously were taken into consideration with respect to their propositional capability and were compared with the scintigram findings. For the formation of the negative brain scintigrams there could be found no unique cause or causal constellation. The scintigraphic tumor representation is likely based on a complex process. Therefore the reasons for the negativity of the brain scintigrams can be a manifold of causes. An important role plays the vascularisation of the tumor, but not in a sole way. As well the tumor localisation gains some importance; especially in the temporal lobe or in the deeper structures situated tumors can be negative in the scintigram. To hold down the rate of wrong-negative quote in the case of intracranial tumor search, one is advised to continue with an further exposure after 2 to 4 hours besides the usual exposures, unless a sequential scintigraphy was made from the beginning. (orig./MG)

  7. Queries with Guarded Negation (full version)

    CERN Document Server

    Barany, Vince; Otto, Martin

    2012-01-01

    A well-established and fundamental insight in database theory is that negation (also known as complementation) tends to make queries difficult to process and difficult to reason about. Many basic problems are decidable and admit practical algorithms in the case of unions of conjunctive queries, but become difficult or even undecidable when queries are allowed to contain negation. Inspired by recent results in finite model theory, we consider a restricted form of negation, guarded negation. We introduce a fragment of SQL, called GN-SQL, as well as a fragment of Datalog with stratified negation, called GN-Datalog, that allow only guarded negation, and we show that these query languages are computationally well behaved, in terms of testing query containment, query evaluation, open-world query answering, and boundedness. GN-SQL and GN-Datalog subsume a number of well known query languages and constraint languages, such as unions of conjunctive queries, monadic Datalog, and frontier-guarded tgds. In addition, an a...

  8. Negative evaluations of negative alcohol consequences lead to subsequent reductions in alcohol use.

    Science.gov (United States)

    Barnett, Nancy P; Merrill, Jennifer E; Kahler, Christopher W; Colby, Suzanne M

    2015-12-01

    Alcohol use during young adulthood may reflect a learning process whereby positive and negative alcohol-related experiences and interpretations of those experiences drive subsequent behavior. Understanding the effect of consequences and the evaluation of consequences could be informative for intervention approaches. The objective of this study was to examine the extent to which the number of positive and negative alcohol consequences experienced and the evaluation of those consequences predict subsequent alcohol use and consequences in college students. Students at 3 colleges (N = 679) completed biweekly web-based surveys on alcohol use, positive and negative consequences, and consequence evaluations for 2 academic years. Hierarchical linear modeling tested whether consequences and evaluations in a given week predicted changes in alcohol use and consequences at the next assessment. Moderation by gender and class year were also evaluated. Evaluating past-week negative consequences more negatively than one's average resulted in decreases in alcohol use at the next assessment. More negative evaluation of negative consequences was followed in the subsequent observation by a higher number of positive consequences for females but not for males. A higher number of positive consequences in a given week was followed by a higher number of both positive and negative consequences in the subsequent observation. Number of negative consequences experienced and evaluation of positive consequences had no effect on later behavior. Salient negative consequences may drive naturalistic reductions in alcohol use, suggesting the possible efficacy of programs designed to increase the salience of the negative effects of alcohol. PMID:26168225

  9. English Communication on Migration and Measures to Overcome the Negative Culture

    Institute of Scientific and Technical Information of China (English)

    陈婉媛

    2016-01-01

    Since the reform and opening up, China has more opportunities and European countries, exchanges and cooperation. However, in the process of communication, we may inadvertently ignore each other's culture and customs, the lack of cross-cul-tural communication awareness in local culture to measure the culture of other countries, such behavior is called negative trans-fer culture. Negative Transfer of Culture will have cultural misunderstandings and conflicts between nations and hinder the smooth progress of cross-cultural communication. In order to avoid unnecessary misunderstanding, strengthen the friendship be-tween different countries, we should understand, learn and overcome cultural negative transfer. This will combine theoretical knowledge and examples to explain the culture, language and culture negative relationship between migration and elaborate cul-tural negative transfer of two levels:Negative Transfer negative transfer surface culture and deep culture (including values mi-gration and ethnic psychological aspects), and its negative impact on the English cross-cultural communication. In addition, this paper will propose some strategies and corresponding to the principle of helping people overcome the negative transfer in cross-cultural communication, enhance cross-cultural communication ability, up from psychological acceptance, adaptation, and toler-ance of different cultures.

  10. Token reinforcement therapeutic approach is more effective than exercise for controlling negative symptoms of schizophrenic patients: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    A Gholipour

    2012-01-01

    Conclusion: Both exercise and token-behavior therapies, along with drug treatment, are very effective in reducing the negative symptoms of schizophrenia; but the impact of token therapy issignificantly higher.

  11. The interplay of personality and negative comments about appearance in predicting body image.

    Science.gov (United States)

    Kvalem, Ingela Lundin; von Soest, Tilmann; Roald, Helge E; Skolleborg, Knut Chr

    2006-09-01

    This study investigates how personality traits in combination with frequency of and emotional reaction to negative comments about appearance while growing up are related to appearance evaluation and orientation among adult women. Nine hundred and seven participants from a representative sample of Norwegian women aged 22-55, answered questions measuring body image, personality (Big Five), and history of experiencing negative comments about appearance. Results indicated that only emotional reaction to negative comments about appearance significantly predicted both appearance evaluation and orientation, while frequency of negative comments did not. Being extrovert predicted more positive appearance evaluation and being more appearance oriented than being introvert. Scoring high on neuroticism was related to negative appearance evaluation and high appearance orientation. The findings demonstrate the importance of differentiating between the frequency and the emotional impact of teasing as well as including personality traits when studying body image. PMID:18089229

  12. Does individualism bring happiness? Negative effects of individualism on interpersonal relationships and happiness

    Directory of Open Access Journals (Sweden)

    Yuji eOgihara

    2014-03-01

    Full Text Available We examined the negative effects of individualism in an East Asian culture. Although individualistic systems decrease interpersonal relationships through competition, individualistic values have prevailed in European American cultures. One reason is because individuals could overcome negativity by actively constructing interpersonal relationships. In contrast, people in East Asian cultures do not have such strategies to overcome the negative impact of individualistic systems, leading to decreased well-being. To test this hypothesis, we investigated the relationship between individualistic values, number of close friends, and subjective well-being (SWB. Study 1 indicated that individualistic values were negatively related with the number of close friends and SWB for Japanese college students but not for American college students. Moreover, Study 2 showed that even in an individualistic workplace in Japan, individualistic values were negatively related with the number of close friends and SWB. We discuss how cultural change toward increasing individualism might affect interpersonal relationships and well-being.

  13. Impact of Advertisement on Malay Young Consumers

    Directory of Open Access Journals (Sweden)

    Asif Khurshid

    2016-02-01

    Full Text Available The purpose of writing this paper is to explore the understanding of advertisement and its impact on young consumers. Also it was discussed that how this impact if it is negative can be neutralized. It has been identified after conducting in depth interviews that all respondents were of the opinion that advertisement is a source of communication. In addition to this all respondents are agreed that it has positive as well as negative effects on both children and young adults. Negative impacts can be diluted by advertisers, parents, government and neighbours.

  14. Softening the blow : Company self-disclosure of negative information lessens the damaging effects on consumer judgment and decision making

    NARCIS (Netherlands)

    Fennis, Bob M.; Stroebe, Wolfgang

    2014-01-01

    Is self-disclosure of negative information a viable strategy for a company to lessen the damage done to consumer responses? Three experiments assessed whether self-disclosing negative information in itself lessened the damaging impact of this information compared to third-party disclosure of the sam

  15. Softening the Blow : Company Self-Disclosure of Negative Information Lessens Damaging Effects on Consumer Judgment and Decision Making

    NARCIS (Netherlands)

    Fennis, Bob M.; Stroebe, Wolfgang

    2014-01-01

    Is self-disclosure of negative information a viable strategy for a company to lessen the damage done to consumer responses? Three experiments assessed whether self-disclosing negative information in itself lessened the damaging impact of this information compared to third-party disclosure of the sam

  16. GDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastatic Breast Cancer

    Science.gov (United States)

    2015-08-17

    Estrogen Receptor Negative Breast Cancer; Human Epidermal Growth Factor 2 Negative Carcinoma of Breast; Triple Negative Breast Cancer; Recurrent Breast Cancer; Stage IV Breast Cancer; Triple-negative Breast Cancer

  17. Realism’s understanding of negative numbers

    Directory of Open Access Journals (Sweden)

    Bojanić Petar

    2016-01-01

    Full Text Available Our topic is the understanding of the nature of negative numbers - the entities to which expressions such as ‘-1’ refer. Following Frege, we view positive whole numbers as providing the answer to the question „how many?“ In this light, how are we to view negative numbers? Both positive and negative numbers can be ordered through the relation of larger or smaller. It is then true of all negative numbers that they are entities which are (somehow smaller than zero. For many, this has been understood as an ontological paradox: how can something be „less than nothing?“ Some propose to avoid the paradox by treating negative numbers as mere façons de parler. In this paper, we propose a more realist account, taking as our starting point the thesis that there is at least one familiar type of object, the magnitude of which can be expressed with negative numbers, namely, debt. How can the sense of an expression be ontologically paradoxical, yet the expression itself still plausibly refer to a social object such as a debt? Or, put differently, how is it possible to be, at the same time, a realist in financial theory and a nominalist in mathematical theory? The paper first shows that the paradox arises when the two distinct ways in which negative numbers are connected to real objects are run together. The first of the two refers to debt only, whereas the second could refer to debt, as well as to physical objects. Finally, we claim that a debt is at once a specifically social object and part of reality as described by physics.

  18. Towards enhanced CSR impact?

    International Nuclear Information System (INIS)

    This paper was produced by ECON Analysis in conjunction with the Fridtjof Nansen Institute (FNI) for the Norwegian Research Council's 'Petropol' programme. It is part of a joint project entitled, 'Oil companies and the new petroleum provinces: ethics, business and politics'. This paper examines the possibilities for partnerships between oil companies and multilateral government institutions to address the negative impacts of oil projects that often prevent the resulting revenues leading to social and economic benefits for the host country (author) (ml)

  19. Quarks possibly are negative mass magnetic monopoles

    International Nuclear Information System (INIS)

    Nonlinear gravitational effects require magnetic monopoles to have negative mass. We therefore propose the hypothesis that quarks are magnetic monopoles of negative mass. The positive mass of hadrons is explained as a result of the positive binding energy from the interaction of negative mass quarks. The production of free quarks would be accompanied by the delivery of a very large amount of energy in excess of the hadronic rest mass energy. Consistently with the smallness of the CP violation the interaction is assumed to be a Heisenberg-type magnetic charge exchange force. The negative mass hypothesis may explain the difficulty to produce free quarks. Free quarks could be produced in very strong magnetic fields of the order approximately 1017 Gauss which may occur in the focus of short wave X-ray laser beams and in the gravitational collapse of massive astronomical objects, explaining the large energy output believed to be associated with quasars. By doping solid material with negative mass quarks one could obtain superstrong materials, and macroscopic bodies approaching arbitrarily close a state of zero rest mass. The most profound consequence of such a state of matter would be in the attainability of relativistic velocities for macroscopic bodies. (orig.)

  20. UNDERSTANDING THE NEGATIVE EFFECTS OF SOCIAL-NETWORKING FACEBOOK ON WOMEN

    OpenAIRE

    BRUNEI, Mohd Aliff MOHD NAWI -; REN, Chua CHY

    2014-01-01

    The phenomenon of a rapidly growing social networking site, Facebook has started to give a massive impact on the users. The aim of this study is to examine the influence of Facebook for users, especially to the women. This study will apply qualitative methods, through literature review and document analysis of past studies. The results showed that Facebook gives more negative impact, and if it is not properly controlled, it will be exploited for other dreadful purposes. At the end of this pap...

  1. Does tax enforcement counteract the negative effects of terrorism? A case study of the Basque country

    OpenAIRE

    Salvadori, Luca

    2015-01-01

    This paper analyses the impact of terrorism on tax enforcement policies by focusing on the case of the Basque Country. The presence of externalities in tax administration attributable to the costs of terrorism is investigated by undertaking a theoretical analysis. The findings of this are tested using Spanish data extracted from repeated surveys and other sources. By employing ordered response models, evidence is found of the negative impact of terrorism on tax enforcement as it is perceived ...

  2. Preservation Copying Endangered Historic Negative Collections

    DEFF Research Database (Denmark)

    Kejser, Ulla Bøgvad

    2008-01-01

    files in a digital repository and outputting the copies on film, which is preserved in a traditional storage facility. The issues are put into perspective by a case study completed at the Royal Library, where endangered nitrate negatives of unique national value have been digitized. The paper starts by...... cost-effective preservation solution for large format negatives is to keep the preservation copies as digital files. However, it also acknowledges that it is important to revisit such strategies regularly to monitor changes in user expectations, technologies and costs.......This article discusses preservation copying of unstable B&W nitrate and acetate still photographic negatives. It focuses on evaluating two different strategies for preserving the copies from a point of view of quality and cost-effectiveness. The evaluated strategies are preservation of the master...

  3. WHEN ONE MIGHT EXPECT NEGATIVE DISCOUNT RATE?

    Directory of Open Access Journals (Sweden)

    Marcin Palenik

    2012-12-01

    Full Text Available Both in economics and psychology, positive discount rate is usually assumed as an axiom. However, there are circumstances which may lead to negative discount rate. This article presents such a phenomenon. Moreover, author presents particular cases of theories and models which imply preference of receiving lower income in later period of time, rather than higher income in earlier period of time (“less later than more earlier”. The described models are as follows: Life Cycle Hypothesis together with Self Control Theory, Construal Level Theory, Model of Patience Formation and Loewenstein’s Anticipation Model. Authors conclude that there is a need of empirical research verifying implications of these models concerning negative discount rate. Authors believe that the problem of negative discount rate deserves more attention, taking into account that in developed countries interest rates are close to zero and it still does not discourage customers from putting money aside.

  4. On Unique Games with Negative Weights

    CERN Document Server

    Cui, Peng

    2011-01-01

    In this paper, the author defines Generalized Unique Game Problem (GUGP), where weights of the edges are allowed to be negative. Focuses are made on two special types of GUGP, GUGP-NWA, where the weights of all edges are negative, and GUGP-PWT($\\rho$), where the total weight of all edges are positive and the negative/positive ratio is at most $\\rho$. The author investigates the counterparts of the Unique Game Conjecture for the two types of generalized unique game problems. The author proves Unique Game Conjecture holds false on GUGP-NWA by giving a factor 2 approximation algorithm for Max GUGP-NWA, and Unique Game Conjecture holds true on GUGP-PWT(1) by reducing the parallel repetition of Max 3-Cut Problem to GUGP-PWT(1). The author poses an open problem whether Unique Game Conjecture holds true on GUGP-PWT($\\rho$) with $0<\\rho<1$.

  5. News Media Framing of Negative Campaigning

    DEFF Research Database (Denmark)

    Pedersen, Rasmus Tue

    2014-01-01

    News media coverage of election campaigns is often characterized by use of the strategic game frame and a focus on politicians’ use of negative campaigning. However, the exact relationship between these two characteristics of news coverage is largely unexplored. This article theorizes that consumer...... demand and norms of journalistic independence might induce the news media outlets to cover negative campaigning with a strategic game frame. A comprehensive content analysis based on several newspaper types, several election campaigns, and several different measurements of media framing confirms...... that news coverage of negative campaigning does apply the strategic game frame to a significantly larger degree than articles covering positive campaigning. This finding has significant implications for campaigning politicians and for scholars studying campaign and media effects....

  6. Negative coupled inductors for polyphase choppers

    Science.gov (United States)

    Jamieson, Robert S. (Inventor)

    1984-01-01

    A technique for negatively coupling the outputs of polyphase choppers is disclosed, wherein the output inductance of each phase is divided into two windings, and each winding is negatively coupled to a corresponding winding of a neighboring phase. In a preferred embodiment for a three-phase chopper circuit, the output inductance of phase A is divided into windings 100 and 102, the output inductance of phase B is divided into windings 110 and 112, and the output inductance of phase C is divided into windings 120 and 122. Pairs of windings 100 and 110, 112 and 120, and 102 and 122 are respectively disposed in transformers arranged for negatively coupling the windings of each pair.

  7. Carpal ligamentous disruptions and negative ulnar variance

    International Nuclear Information System (INIS)

    Negative ulnar variance is a condition in which the ulna is relatively shorter than the radius at the carpus. It was found in 21% of 203 normal wrists. We have observed an increased incidence (49%) of this anomaly in patients with carpal ligamentous instabilities (dorsiflexion instability, palmar flexion instability, scapholunate dissociation with rotary luxation of the scaphoid, and lunate and perilunate dislocations). While the reasons for this association have yet to be adequately delineated, the presence of a negative ulnar variant may serve as an impartial clue to the presence of ligamentous instability. Many carpal instabilities present with subtle radiographic findings requiring careful evaluation of radiographs. Patients with negative ulnar variance and histories suggestive of ligamentous instability should undergo careful radiologic evaluation to assure early diagnosis of carpal disruption. (orig.)

  8. A new bivariate negative binomial regression model

    Science.gov (United States)

    Faroughi, Pouya; Ismail, Noriszura

    2014-12-01

    This paper introduces a new form of bivariate negative binomial (BNB-1) regression which can be fitted to bivariate and correlated count data with covariates. The BNB regression discussed in this study can be fitted to bivariate and overdispersed count data with positive, zero or negative correlations. The joint p.m.f. of the BNB1 distribution is derived from the product of two negative binomial marginals with a multiplicative factor parameter. Several testing methods were used to check overdispersion and goodness-of-fit of the model. Application of BNB-1 regression is illustrated on Malaysian motor insurance dataset. The results indicated that BNB-1 regression has better fit than bivariate Poisson and BNB-2 models with regards to Akaike information criterion.

  9. Goffman, Parsons, and the Negational Self

    Directory of Open Access Journals (Sweden)

    James J. Chriss

    2015-01-01

    Full Text Available Erving Goffman’s emphasis on impression management in everyday life means that for the most part persons offer only partial or incomplete glimpses of themselves. Indeed, under specifiable conditions self-presentations may take the form of a negational self. If negational selves exist at the person or individual level, then they must also exist at the collective level (that is, if we are to take seriously such notions as the social mind, collective representations, or even culture. Understandings of how this negational self appears and is produced at various analytical levels (micro, meso, and macro can be anchored via a conceptual schema which merges Goffman’s own identity typology with the three-world model of Jürgen Habermas by way of Talcott Parsons.

  10. Animal Reasoning: Negation and Representations of Absence.

    Directory of Open Access Journals (Sweden)

    Morales Ladrón de Guevara, Jorge

    2011-05-01

    Full Text Available In this paper I reject the possibility that animal reasoning, negation in particular, necessarily involves the representation of Absence, as suggested by José Luis Bermúdez, since this would still work as a logical negation (unavailable for non-linguistic creatures. False belief, pretense, and communication experiments show that non-human animals (at least some primates have difficulties representing absent entities or properties. I offer an alternative account resorting to the sub-symbolic similarity judgments proposed by Vigo & Allen and I introduce the notion of expectation: animal proto-negation takes place through the incompatibility between an expected and the actual representation. Finally, I propose that the paradigm of expectations can be extrapolated to other experiments in cognitive psychology (both with pre-linguistic children and animals in order to design “fair” experiments which test other minds considering their true abilities.

  11. Osmosis at constant volume. Negative pressure

    CERN Document Server

    Zupanovic, Pasko; Brumen, Milan; Fajmut, Ales; Juretic, Davor

    2009-01-01

    A thermodynamic state of solvent and solution separated with an elastic semipermeable membrane, in the box with a fixed volume, is considered. It is shown that the minimum of the free energy is accompanied by the compression of the solution and tension of the solvent caused by the transfer of solvent molecules into compartment with solution. The tensile state of the solvent is described in terms of negative pressure. It is found that the negative pressure as well as compression pressure is of the order of osmotic pressure given by van't Hoff equation. It is proposed that this mechanism could be responsible for the water uptake in tall trees.

  12. Elastic properties of water under negative pressures

    Energy Technology Data Exchange (ETDEWEB)

    Alvarenga, A.D.; Grimsditch, M. (Materials Science Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States)); Bodnar, R.J. (Department of Geological Sciences, Virginia Polytechnic Institute, Blacksburg, Virginia 24061 (United States))

    1993-06-01

    Using Brillouin scattering we have investigated the elastic properties of water under negative pressures. The samples were H[sub 2]O liquid--vapor inclusions in [alpha]-quartz which could be heated to their homogenization temperatures (in the range 120--370 [degree]C); on cooling, negative pressures as high as 1000 bars were reached before a vapor bubble nucleated. The velocity of sound results obtained from our Brillouin experiments indicate that nucleation occurs long before reaching the mechanical instability region where the bulk modulus is zero.

  13. GPM Solar Array Gravity Negated Deployment Testing

    Science.gov (United States)

    Penn, Jonathan; Johnson, Chris; Lewis, Jesse; Dear, Trevin; Stewart, Alphonso

    2014-01-01

    NASA Goddard Space Flight Center (GSFC) successfully developed a g-negation support system for use on the solar arrays of the Global Precipitation Measurement (GPM) Satellite. This system provides full deployment capability at the subsystem and observatory levels. In addition, the system provides capability for deployed configuration first mode frequency verification testing. The system consists of air pads, a support structure, an air supply, and support tables. The g-negation support system was used to support all deployment activities for flight solar array deployment testing.

  14. Negative-Index Media for Matter Waves

    Science.gov (United States)

    Perales, F.; Bocvarski, V.; Baudon, J.; Hamamda, M.; Grucker, J.; Dutier, G.; Mainos, C.; Boustimi, M.; Ducloy, M.

    2010-02-01

    One reviews the recently introduced field of matter-wave "meta-optics", i.e. the extension of optical negative-index media (NIM) to atom optics. After emphasizing the differences with light meta-optics and particularly the necessary transient character of NIM's in atom optics, we present the way of generating matter-wave NIM's and their general properties: negative refraction, atom meta-lenses. Finally their specific features are reviewed: longitudinal wave packet narrowing associated to a time-reversal effect, transient revivals of evanescent matter waves and atom reflection echoes at a potential barrier.

  15. A Negative Permeability Material at Red Light

    DEFF Research Database (Denmark)

    Yuan, Hsiao-Kuan; Chettiar, Uday K.; Cai, Wenshan;

    2007-01-01

    A negative permeability in a periodic array of pairs of thin silver strips is demonstrated experimentally for two distinct samples. The effect of the strip surface roughness on negative permeability is evaluated. The first sample, Sample A, is fabricated of thinner strips with a root mean square...... roughness of 7 nm, while Sample B is made of thicker strips with 3-nm roughness. The real part of permeability, μ ′ , is −1 at a wavelength of 770 nm in Sample A and −1.7 at 725 nm in Sample B. Relative to prototypes simulated with ideal strips, larger strip roughness acts to decrease μ ′ by a factor of 7...

  16. Generalized Cherry oscillators and negative energy waves

    International Nuclear Information System (INIS)

    In 1925 Cherry discussed two oscillators of positive and negative energy that are nonlinearly coupled in a special way, and presented exact solutions of the nonlinear equations showing explosive instabilities independent of the strength of the nonlinearity and the initial amplitudes. In this paper Cherry's Hamiltonian is transformed into a form which allows a simple physical interpretation. The new Hamiltonian is generalized to three nonlinearly coupled oscillators; it corresponds to three-wave interaction in a continuum theory, like the Vlasov-Maxwell theory, if there exist linear negative energy waves. (orig.)

  17. Real and imaginary negative binomial states

    Science.gov (United States)

    Liao, Jing; Wang, Xiaoguang; Wu, Ling-An; Pan, Shao-Hua

    2001-10-01

    The real and imaginary negative binomial states formed by a superposition of the negative binomial states are introduced. The sub-Poissonian statistics, Wigner function and squeezing properties of the real and imaginary states are studied in detail. The oscillatory character of the photon distribution due to the quantum interference between the two components is shown. Moreover, we find that these states are real and imaginary nonlinear Schrödinger cat states and give the corresponding ladder operator formalisms. We also discuss how to generate these general real quantum superposition states based on the intensity-dependent Jaynes-Cummings model.

  18. Towards the development of improved tests for negative symptoms of schizophrenia in a validated animal model.

    Science.gov (United States)

    Sahin, Ceren; Doostdar, Nazanin; Neill, Joanna C

    2016-10-01

    Negative symptoms in schizophrenia remain an unmet clinical need. There is no licensed treatment specifically for this debilitating aspect of the disorder and effect sizes of new therapies are too small to make an impact on quality of life and function. Negative symptoms are multifactorial but often considered in terms of two domains, expressive deficit incorporating blunted affect and poverty of speech and avolition incorporating asociality and lack of drive. There is a clear need for improved understanding of the neurobiology of negative symptoms which can be enabled through the use of carefully validated animal models. While there are several tests for assessing sociability in animals, tests for blunted affect in schizophrenia are currently lacking. Two paradigms have recently been developed for assessing negative affect of relevance to depression in rats. Here we assess their utility for studying negative symptoms in schizophrenia using our well validated model for schizophrenia of sub-chronic (sc) treatment with Phencyclidine (PCP) in adult female rats. Results demonstrate that sc PCP treatment produces a significant negative affect bias in response to a high value reward in the optimistic and affective bias tests. Our results are not easily explained by the known cognitive deficits induced by sc PCP and support the hypothesis of a negative affective bias in this model. We suggest that further refinement of these two tests will provide a means to investigate the neurobiological basis of negative affect in schizophrenia, thus supporting the assessment of efficacy of new targets for this currently untreated symptom domain. PMID:27312268

  19. The Economic and Social Impact of Tourism

    OpenAIRE

    Arroyo, Gloria M; San Buenaventura, Mariano

    1983-01-01

    This paper analyzes the economic and social impact of tourism in Pagsanjan in which tourism development project is located. Results show that the project’s various significant impacts include increases in employment and income and stimulation of political and women’s participation. While its impact on environment and on the people’s social life has been a mixture of positive and negative results, its impact on income distribution has been trifling. To maximize the tourism multiplier, the pape...

  20. Examining the latent structure of negative symptoms: is there a distinct subtype of negative symptom schizophrenia?

    Science.gov (United States)

    Blanchard, Jack J; Horan, William P; Collins, Lindsay M

    2005-09-15

    Negative symptoms have emerged as a replicable factor of symptomatology within schizophrenia. Although rating scales provide assessments along dimensions of severity, categorization into a negative symptom subtype is typically conducted. A categorical view of negative symptoms is best reflected in the proposal that enduring, primary negative symptoms, or deficit symptoms, reflect a distinct subtype of schizophrenia . Despite an accumulation of findings that support a categorical conceptualization, the data are also consistent with a dimensional-only model where negative symptom subtypologies simply reflect an extreme on a continuum of severity. Using taxometric statistical methods , the present study examined whether a taxonic, or latent class, model best describes negative symptoms in a sample of 238 schizophrenia patients. In order to obtain more stable estimates of symptoms, ratings on the Scale for the Assessment of Negative Symptoms [Andreasen, N.C., 1982. Negative symptoms in schizophrenia: Definition and reliability. Arch. Gen. Psychiatry 39, 784-788.] were averaged across two assessments over a 6-month period. Two taxometric methods, maximum covariance analysis (MAXCOV) and mean above minus below a cut (MAMBAC) identified a latent class or taxon with a base rate of approximately 28-36%. Members of the negative symptom taxon differed from the nontaxon class in that taxon members were more likely to be male and demonstrated poorer social functioning. Taxon and nontaxon schizophrenia patients did not differ in psychotic or affective symptoms. The findings converge to provide support for a categorical view of negative symptoms. Further research is required to replicate the present taxonic findings and to examine characteristics (including possible etiological factors) associated with this negative symptom taxon. PMID:15916881

  1. Impact Velocity and Coefficient of Restitution for a Tennis Ball Impacting a Tennis Racquet

    OpenAIRE

    Mongkol Sukpraprut

    2015-01-01

    The impact and exit velocities of a tennis ball impacting on a fixed tennis racquet were measured with high speed video analysis to determine the coefficient of restitution (COR). It was found that there is a negative linear relationship between the COR and the impact velocity of the ball for velocities between 13 and 36 m/s.

  2. Impact Velocity and Coefficient of Restitution for a Tennis Ball Impacting a Tennis Racquet

    Directory of Open Access Journals (Sweden)

    Mongkol Sukpraprut

    2015-01-01

    Full Text Available The impact and exit velocities of a tennis ball impacting on a fixed tennis racquet were measured with high speed video analysis to determine the coefficient of restitution (COR. It was found that there is a negative linear relationship between the COR and the impact velocity of the ball for velocities between 13 and 36 m/s.

  3. Negative running can prevent eternal inflation

    International Nuclear Information System (INIS)

    Current data from the Planck satellite and the BICEP2 telescope favor, at around the 2 σ level, negative running of the spectral index of curvature perturbations from inflation. We show that for negative running α < 0, the curvature perturbation amplitude has a maximum on scales larger than our current horizon size. A condition for the absence of eternal inflation is that the curvature perturbation amplitude always remain below unity on superhorizon scales. For current bounds on nS from Planck, this corresponds to an upper bound of the running α < −9 × 10−5, so that even tiny running of the scalar spectral index is sufficient to prevent eternal inflation from occurring, as long as the running remains negative on scales outside the horizon. In single-field inflation models, negative running is associated with a finite duration of inflation: we show that eternal inflation may not occur even in cases where inflation lasts as long as 104 e-folds

  4. Further Conceptualization of Explanation in Negative Messages.

    Science.gov (United States)

    Limaye, Mohan R.

    1997-01-01

    Makes two suggestions for presentation in the classroom and in textbooks of business communication regarding explanation in negative messages: (1) providing a reasonable explanation is the sender's moral obligation, and receiving such explanation is a natural right of the target; and (2) explanation should be presented on two levels: general and…

  5. On hypergeometric generalized negative binomial distribution

    OpenAIRE

    Ghitany, M. E.; Al-Awadhi, S. A.; S. L. Kalla

    2002-01-01

    It is shown that the hypergeometric generalized negative binomial distribution has moments of all positive orders, is overdispersed, skewed to the right, and leptokurtic. Also, a three-term recurrence relation for computing probabilities from the considered distribution is given. Application of the distribution to entomological field data is given and its goodness-of-fit is demonstrated.

  6. On hypergeometric generalized negative binomial distribution

    Directory of Open Access Journals (Sweden)

    M. E. Ghitany

    2002-01-01

    Full Text Available It is shown that the hypergeometric generalized negative binomial distribution has moments of all positive orders, is overdispersed, skewed to the right, and leptokurtic. Also, a three-term recurrence relation for computing probabilities from the considered distribution is given. Application of the distribution to entomological field data is given and its goodness-of-fit is demonstrated.

  7. Negative Effects from Psychological Treatments: A Perspective

    Science.gov (United States)

    Barlow, David H.

    2010-01-01

    The author offers a 40-year perspective on the observation and study of negative effects from psychotherapy or psychological treatments. This perspective is placed in the context of the enormous progress in refining methodologies for psychotherapy research over that period of time, resulting in the clear demonstration of positive effects from…

  8. Veillonella, Firmicutes: Microbes disguised as Gram negatives

    DEFF Research Database (Denmark)

    Vesth, Tammi Camilla; Ozen, Asli; Andersen, Sandra Christine;

    2013-01-01

    the exception of a shared LPS biosynthesis pathway. The clade within the class Negativicutes to which the genus Veillonella belongs exhibits unique properties, most of which are in common with Gram-positives and some with Gram negatives. They are only distantly related to Clostridia, but are even less...

  9. Revisiting the gram-negative lipoprotein paradigm

    Science.gov (United States)

    The processing of lipoproteins (lpps) in Gram-negative bacteria is generally considered to be an essential pathway. Mature lipoproteins in these bacteria are triacylated, with the final fatty acid addition performed by Lnt, an apolipoprotein n-acyltransferase. The mature lipoproteins are then sorted...

  10. Negative Refraction experiments in Photonic Crystal prisms

    Science.gov (United States)

    Vodo, Plarenta; Parimi, Patanjali. V.; Lu, Wentao. T.; di Gennaro, Emiliano; Sridhar, Srinivas

    2004-03-01

    We have experimentally demonstrated negative refraction in metallic photonic crystal (PC) prisms [1]. The refracted fields in the parallel plate waveguide (PPW) are measured by an automated dipole antenna, which scans the desired area, while the free space (FS) measurements, performed in a anechoic chamber, are measured by a rectangular X-band horn that swings in an arc in far field area. Both TE and TM excitation modes are used in FS experiments. Numerical calculations of the band structure and equi-frequency surface simulations are used to determine frequency regions of negative refraction of the triangular lattice PC. Angle of refraction determined by theoretical simulations and experimental results, are in exceptional good agreement, yielding the negative refraction index. FS and PPW refraction experimental results agree remarkably with simulations. 1. "Negative Refraction and Left-handed electromagnetism in Microwave Photonic Crystals", P.V Parimi, W.T Lu, P.Vodo J. Sokoloff and S.Sridhar, cond-mat/0306109 (2003)

  11. Negative pressure wound therapy: clinical utility

    Directory of Open Access Journals (Sweden)

    Sandoz H

    2015-04-01

    Full Text Available Heidi Sandoz Accelerate CIC, Mile End Hospital, London, UK Abstract: Negative pressure wound therapy (NPWT, also known as topical negative pressure therapy, has been increasingly used in health care for the management of a wide variety of wounds over the last 2–3 decades. It is an advanced therapy that can be helpful to accelerate wound healing in both acute and chronic wounds by delivering negative pressure (suction to the wound bed. More recent advancements in the application of NPWT have provided clinicians with wider choices of utilization. There are now devices available that can deliver irrigation to the wound bed, be used for closed surgical incisions, or are disposable and highly portable. Systematic reviews considering NPWT have been published previously. These usually focus on one wound group or device and fail to offer practical clinical guidance due to the scrutiny offered to the evidence via a systematic review process. Here, an overview of the history of NPWT, the varieties of device available, their wide clinical application, and the evidence to support its use are explored in a pragmatic way. Keywords: negative pressure, wound, incision, healing, pain 

  12. The negative brain scintiscan in brain tumours

    International Nuclear Information System (INIS)

    On the basis of 53 histologically verified and two histologically unidentified brain tumours, the author examined the reasons for these wrongly negative scintiscans. EEGs and angiographies carried out at about the same time were taken into account and compared with the scintigraphic findings. (orig.)

  13. Magnetic levitation induced by negative permeability

    OpenAIRE

    Rangelov, A. A.

    2011-01-01

    In this paper we study the interaction between a point magnetic dipole and a semi-infinite metamaterial using the method of images. We obtain analytical expressions for the levitation force for an arbitrarily oriented dipole. Surprisingly the maximal levitation force for negative permeability is found to be stronger compared to the case when the dipole is above a superconductor.

  14. Attribution of Negative Intention in Williams Syndrome

    Science.gov (United States)

    Godbee, Kali; Porter, Melanie A.

    2013-01-01

    People with Williams syndrome (WS) are said to have sociable and extremely trusting personalities, approaching strangers without hesitation. This study investigated whether people with WS are less likely than controls to attribute negative intent to others when interpreting a series of ambiguous pictures. This may, at least partially, explain…

  15. Impacts of negative emotions on interpersonal trust:Clues effects based on trust game%消极情绪影响人际信任的线索效应:基于信任博弈范式的检验

    Institute of Scientific and Technical Information of China (English)

    李常洪; 高培霞; 韩瑞婧; 宋志红

    2014-01-01

    The influence of emotional states on trust has drawn much attention. This research attempted to ex-plain how negative emotions and clues about the trustee influence the trusting behaviors,and compared the differences between the two negative emotions(anger and sadness)by an experiment. In our experiment,the subkects were induced to different negative emotions or neutral feelings with emotional video clips and then turned to the trust game with some clues about the trustees. The results revealed that the subkect’s amounts of trust investment were influenced by the trustworthy clues and the emotions the subkect experienced. Specifical-ly,in case that the available cues promoted trust,people having negative emotions decreased their trust than those experiencing neutral emotions,but the distrust cues rendered no difference. Furthermore,the result shows that,consistent with the theoretical prediction which argues that angry subkects will render more reliance upon the available clues and schemas than sad ones,these two different kinds of negative emotions influence trust in different ways:compared with the sad ones,angry people significantly increased their amounts of trust investment in the case that the trustee clues promoted trust,and decreased their amounts of trust investment when clues promoted distrust. These findings are discussed in terms of emotional effects on cognitive strate-gies;this study can be a valuable complement to the Accommodation-Assimilation Model and have implications for trust development within organizations.%采用信任博弈范式,通过诱发愤怒、悲伤两种消极情绪和中性情绪,考察不同情绪状态的个体进行陌生人初始信任判断是否存在对信任线索的依赖性,即线索效应。研究结果显示当社会线索指向可信时,消极情绪普遍比中性情绪引起的信任水平低,而在社会线索指向不可信时,消极情绪和中性情绪并没有显著差别;同时悲伤和愤怒

  16. Civil society perspectives on negative biomedical HIV prevention trial results and implications for future trials.

    Science.gov (United States)

    Essack, Zaynab; Koen, Jennifer; Slack, Catherine; Lindegger, Graham; Newman, Peter A

    2012-01-01

    Community engagement is crucial to ongoing development and testing of sorely needed new biomedical HIV prevention technologies. Yet, negative trial results raise significant challenges for community engagement in HIV prevention trials, including the early termination of the Cellulose Sulfate microbicide trial and two Phase IIb HIV vaccine trials (STEP and Phambili). The present study aimed to explore the perspectives and experiences of civil society organization (CSO) representatives regarding negative HIV prevention trial results and perceived implications for future trials. We conducted in-depth interviews with 14 respondents from a broad range of South African and international CSOs, and analyzed data using thematic analysis. CSO representatives reported disappointment in response to negative trial results, but acknowledged such outcomes as inherent to clinical research. Respondents indicated that in theory negative trial results seem likely to impact on willingness to participate in future trials, but that in practice people in South Africa have continued to volunteer. Negative trial results were described as having contributed to improving ethical standards, and to a re-evaluation of the scientific agenda. Such negative results were identified as potentially impacting on funding for trials and engagement activities. Our findings indicate that trial closures may be used constructively to support opportunities for reflection and renewed vigilance in strategies for stakeholder engagement, communicating trial outcomes, and building research literacy among communities; however, these strategies require sustained resources for community engagement and capacity-building. PMID:22360605

  17. Seeing ghosts: Negative body evaluation predicts overestimation of negative social feedback

    NARCIS (Netherlands)

    Alleva, J.M.; Lange, W.G.; Jansen, A.T.M.; Martijn, C.

    2014-01-01

    The current study investigated whether negative body evaluation predicts women's overestimation of negative social feedback related to their own body (i.e., covariation bias). Sixty-five female university students completed a computer task where photos of their own body, of a control woman's body, a

  18. Positive Effects of Talking about the Negative: Family Narratives of Negative Experiences and Preadolescents' Perceived Competence

    Science.gov (United States)

    Marin, Kelly A.; Bohanek, Jennifer G.; Fivush, Robyn

    2008-01-01

    Family narratives about the past are an important context for the socialization of emotion, but relations between expression of negative emotion and children's emerging competence are conflicting. In this study, 24 middle-class two-parent families narrated a shared negative experience together and we examined the process (initiations and…

  19. Negative ion beam extraction in ROBIN

    Energy Technology Data Exchange (ETDEWEB)

    Bansal, Gourab, E-mail: bansal@ipr.res.in [Institute for Plasma Research (IPR), Bhat, Gandhinagar, Gujarat 382428 (India); Gahlaut, Agrajit; Soni, Jignesh; Pandya, Kaushal; Parmar, Kanu G.; Pandey, Ravi; Vuppugalla, Mahesh; Prajapati, Bhavesh; Patel, Amee; Mistery, Hiren [Institute for Plasma Research (IPR), Bhat, Gandhinagar, Gujarat 382428 (India); Chakraborty, Arun; Bandyopadhyay, Mainak; Singh, Mahendrajit J.; Phukan, Arindam; Yadav, Ratnakar K.; Parmar, Deepak [ITER-India, Institute for Plasma Research, A-29, Sector 25, GIDC, Gandhinagar, Gujarat 380025 (India)

    2013-10-15

    Highlights: ► A RF based negative hydrogen ion beam test bed has been set up at IPR, India. ► Ion source has been successfully commissioned and three campaigns of plasma production have been carried out. ► Extraction system (35 kV) has been installed and commissioning has been initiated. Negative ion beam extraction is immediate milestone. -- Abstract: The RF based single driver −ve ion source experiment test bed ROBIN (Replica Of BATMAN like source in INDIA) has been set up at Institute for Plasma Research (IPR), India in a technical collaboration with IPP, Garching, Germany. A hydrogen plasma of density 5 × 10{sup 12} cm{sup −3} is expected in driver region of ROBIN by launching 100 kW RF power into the driver by 1 MHz RF generator. The cesiated source is expected to deliver a hydrogen negative ion beam of 10 A at 35 kV with a current density of 35 mA/cm{sup 2} as observed in BATMAN. In first phase operation of the ROBIN ion source, a hydrogen plasma has been successfully generated (without extraction system) by coupling 80 kW RF input power through a matching network with high power factor (cos θ > 0.8) and different plasma parameters have been measured using Langmuir probes and emission spectroscopy. The plasma density of 2.5 × 10{sup 11} cm{sup −3} has been measured in the extraction region of ROBIN. For negative hydrogen ion beam extraction in second phase operation, extraction system has been assembled and installed with ion source on the vacuum vessel. The source shall be first operated in volume mode for negative ion beam extraction. The commissioning of the source with high voltage power supply has been initiated.

  20. The sputter generation of negative ion beams

    International Nuclear Information System (INIS)

    A brief review is given of recent progress toward a quantitative understanding of negative ion formation by sputtering from surfaces covered with fractional layers of highly electropositive adsorbates. Practical models developed for estimating changes in work functions Δφ by electropositive adsorbates are described. The secondary negative ion generation process is examined through the use of composite energy/velocity dependent analytical models. These models are used to illustrate the effect of work function on the energy distributions of negative ions sputter ejected from a polycrystalline molybdenum surface covered with fractional layers of cesium. Predictions are also made of the functional dependence of the probability for negative ion formation on cesium coverage. The models predict energy distributions which are in basic disagreement with experimental observations, implying their inappropriateness for describing the sputter negative ion generation process. We have also developed a model for calculating sputter ratios based on the use of simple scaling procedures to bring Sigmund theory into close agreement with experimental observation accounting for the threshold effect. Scaling factors for projectile energies E > 1000 eV are found to be independent of energy while those for projectile energies Eth < E < 1000 eV were found to be energy dependent. In this study, the model and scaling techniques utilized to bring Sigmund theory into agreement with experiment are discussed in detail and several examples provided which illustrate the versatility, accuracy and utility of the model. In the present report, we describe the model and apply it to the case of sputtering a selected number of metals with energetic cesium ions. In particular, we present sputter ratio information for a number of Cs-projectile/metal-target combinations; the targets are bombarded at normal incidence to the surface