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Sample records for blood lead secular

  1. Secular trend of the leading causes of death in China from 2003 to ...

    African Journals Online (AJOL)

    Secular trend of the leading causes of death in China from 2003 to 2013. ... African Health Sciences ... respiratory, and digestive system diseases in urban areas and genito-urinary system diseases in rural areas decreased during this period ...

  2. Total contribution of airborne lead to blood lead.

    OpenAIRE

    Manton, W I

    1985-01-01

    A nine year study of blood lead concentrations and isotope ratios carried out on a married couple shows that pulmonary deposition cannot account for all the airborne lead in blood; that lead from bone may comprise 70% of blood lead; and that during pregnancy blood lead may double due to mobilisation of lead from bone.

  3. Total contribution of airborne lead to blood lead.

    Science.gov (United States)

    Manton, W I

    1985-01-01

    A nine year study of blood lead concentrations and isotope ratios carried out on a married couple shows that pulmonary deposition cannot account for all the airborne lead in blood; that lead from bone may comprise 70% of blood lead; and that during pregnancy blood lead may double due to mobilisation of lead from bone. PMID:3970881

  4. Blood lead levels and chronic blood loss

    Energy Technology Data Exchange (ETDEWEB)

    Manci, E.A.; Cabaniss, M.L.; Boerth, R.C.; Blackburn, W.R.

    1986-03-01

    Over 90% of lead in blood is bound to the erythrocytes. This high affinity of lead for red cells may mean that chronic blood loss is a significant means for excretion of lead. This study sought correlations between blood lead levels and clinical conditions involving chronic blood loss. During May, June and July, 146 patients with normal hematocrits and red cell indices were identified from the hospital and clinic populations. For each patient, age, race, sex and medical history were noted, and a whole blood sample was analyzed by flameless atomic absorption spectrophotometry. Age-and race-matched pairs showed a significant correlation of chronic blood loss with lead levels. Patients with the longest history of blood loss (menstruating women) had the lowest level (mean 6.13 ..mu..g/dl, range 3.6-10.3 ..mu..g/dl). Post-menopausal women had levels (7.29 ..mu..g/dl, 1.2-14 ..mu..g/dl) comparable to men with peptic ulcer disease, or colon carcinoma (7.31 ..mu..g/dl, 5.3-8.6 ..mu..g/dl). The highest levels were among men who had no history of bleeding problems (12.39 ..mu..g/dl, 2.08-39.35 ..mu..g/dl). Chronic blood loss may be a major factor responsible for sexual differences in blood lead levels. Since tissue deposition of environmental pollutants is implicated in diseases, menstruation may represent a survival advantage for women.

  5. Secularism, secular state and religious freedom | Nweke | Journal of ...

    African Journals Online (AJOL)

    The historic separation of the Church and the State, as an immediate product of secularism, informs the reality of secular state, a state without official religion. This paper attempts to understudy the extent to which secularism enhances religious freedom within the frame of secular state. With the tools of phenomenological ...

  6. Metaphysical Concept of Secularization versus Islamic Concept of Secularization

    Directory of Open Access Journals (Sweden)

    Volkan ERTİT

    2017-12-01

    Full Text Available In early 21st century, the question “Is Turkey becoming secularized contrary to popular belief?” was one of the discussions occupying Turkish public opinion. These discussions led to the encounter of two different concepts of secularization, “theological (Islamic” and "metaphysical", and to put forward different claims using the same concept. Hence, it became evidentwas understood that a discussion was necessary to understand what secularization is and what it is not before starting any debate on Turkey's secularization. That is because the metaphysical discussion that defines secularization as the decline in the social influence of metaphysical realm (religion, religion-like mechanisms, folk religions, superstitious beliefs, etc. is overshadowed by the Islamic definition describing secularization as "irreligiousness" or "non-Islamism". Therefore, discussingTo understand the social transformation in Turkey, this article attempts to explain that metaphysical rather than theological definition of secularization is necessary for understanding the social implications of the process of modernization.

  7. Lead levels - blood

    Science.gov (United States)

    Blood lead levels ... is used to screen people at risk for lead poisoning. This may include industrial workers and children ... also used to measure how well treatment for lead poisoning is working. Lead is common in the ...

  8. (Post Secular Discomforts: Religio-Secular Disclosures in the Indian Context

    Directory of Open Access Journals (Sweden)

    Goldie Osuri

    2012-09-01

    Full Text Available The post-secular turn at the intersection of the fields of political philosophy, anthropology, religious, postcolonial and cultural studies has highlighted theological political formations which have informed differential histories of the secular. This essay examines how debates around the secular and the post-secular play out in the Indian context. Some questions that the essay addresses are: What does a reconsideration of the secular, a probing of its discomforts, offer in the Indian context? And what are the limits of a post-secular turn—in the sense of a reconsideration of spiritual belief or theological conventions as a resource for co-existence—if we think through the forms of power generated by this turn?

  9. Blood Test: Lead (For Parents)

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Blood Test: Lead KidsHealth / For Parents / Blood Test: Lead What's ... español Análisis de sangre: plomo What Is a Blood Test? A blood test is when a sample of ...

  10. 85 SECULARISM, SECULAR STATE AND RELIGIOUS FREEDOM ...

    African Journals Online (AJOL)

    finds that, although more feasible within secular states, religious freedom and human rights are possibilities ... and values, nor uses its powers and offices to persecute religion.” According to ... Secularism is in fact an expression of humanism.

  11. Secular Religious Establishment

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2013-01-01

    Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer...... to the compatibility question is not obvious and requires a systematic analysis of secularism. Based on a distinction between a general concept and specific conceptions of secularism I offer a general structure for conceptions of secularism that incorporates both a) basic values, e.g. political equality and freedom...

  12. Secular spirituality versus secular dualism: Towards postsecular ...

    African Journals Online (AJOL)

    The term “secular spirituality” is meant to convey the contemporary phenomenon of spirituality as experienced in different spheres not associated with structured, institutionalised religion. An outline is given of the relation between secular reality (the natural realm) and religious/spiritual reality (the supernatural realm), as it ...

  13. SECULAR CHAOS AND THE PRODUCTION OF HOT JUPITERS

    International Nuclear Information System (INIS)

    Wu Yanqin; Lithwick, Yoram

    2011-01-01

    In a planetary system with two or more well-spaced, eccentric, inclined planets, secular interactions may lead to chaos. The innermost planet may gradually become very eccentric and/or inclined as a result of the secular degrees of freedom drifting toward equipartition of angular momentum deficit. Secular chaos is known to be responsible for the eventual destabilization of Mercury in our own solar system. Here we focus on systems with three giant planets. We characterize the secular chaos and demonstrate the criterion for it to occur, but leave a detailed understanding of secular chaos to a companion paper. After an extended period of eccentricity diffusion, the inner planet's pericenter can approach the star to within a few stellar radii. Strong tidal interactions and ensuing tidal dissipation extract orbital energy from the planet and pull it inward, creating a hot Jupiter. In contrast to other proposed channels for the production of hot Jupiters, such a scenario (which we term 'secular migration') explains a range of observations: the pile-up of hot Jupiters at 3 day orbital periods, the fact that hot Jupiters are in general less massive than other radial velocity planets, that they may have misaligned inclinations with respect to stellar spin, and that they have few easily detectable companions (but may have giant companions in distant orbits). Secular migration can also explain close-in planets as low in mass as Neptune; and an aborted secular migration can explain the 'warm Jupiters' at intermediate distances. In addition, the frequency of hot Jupiters formed via secular migration increases with stellar age. We further suggest that secular chaos may be responsible for the observed eccentricities of giant planets at larger distances and that these planets could exhibit significant spin-orbit misalignment.

  14. Beyond comparing secularisms: a critique of religio-secularism

    NARCIS (Netherlands)

    Jansen, Y.; Zuckerman, P.; Shook, J.R.

    2017-01-01

    “Religio-secularism” denotes the tendency to understand specific cultural and political conflicts in terms an opposition between religion on the one hand and secularism on the other. Religio-secularism as a cultural-political paradigm tends to obscure the intricacies of political, socioeconomic,

  15. Surface dust wipes are the best predictors of blood leads in young children with elevated blood lead levels

    Energy Technology Data Exchange (ETDEWEB)

    Gulson, Brian, E-mail: brian.gulson@mq.edu.au [Graduate School of the Environment, Macquarie University, North Ryde NSW 2109 (Australia); CSIRO Earth Science and Resource Engineering, North Ryde NSW 2113 (Australia); Anderson, Phil [Information and Statistics Group, Australian Institute of Health and Welfare, Canberra ACT 2601 (Australia); Faculty of Health, University of Canberra, Canberra ACT 2601 (Australia); Taylor, Alan [Department of Psychology, Macquarie University, Sydney NSW 2109 (Australia)

    2013-10-15

    Background: As part of the only national survey of lead in Australian children, which was undertaken in 1996, lead isotopic and lead concentration measurements were obtained from children from 24 dwellings whose blood lead levels were ≥15 µg/dL in an attempt to determine the source(s) of their elevated blood lead. Comparisons were made with data for six children with lower blood lead levels (<10 µg/dL). Methods: Thermal ionisation and isotope dilution mass spectrometry were used to determine high precision lead isotopic ratios ({sup 208}Pb/{sup 206}Pb, {sup 207}Pb/{sup 206}Pb and {sup 206}Pb/{sup 204}Pb) and lead concentrations in blood, dust from floor wipes, soil, drinking water and paint (where available). Evaluation of associations between blood and the environmental samples was based on the analysis of individual cases, and Pearson correlations and multiple regression analyses based on the whole dataset. Results and discussion: The correlations showed an association for isotopic ratios in blood and wipes (r=0.52, 95% CI 0.19–0.74), blood and soil (r=0.33, 95% CI −0.05–0.62), and blood and paint (r=0.56, 95% CI 0.09–0.83). The regression analyses indicated that the only statistically significant relationship for blood isotopic ratios was with dust wipes (B=0.65, 95% CI 0.35–0.95); there were no significant associations for lead concentrations in blood and environmental samples. There is a strong isotopic correlation of soils and house dust (r=0.53, 95% CI 0.20–0.75) indicative of a common source(s) for lead in soil and house dust. In contrast, as with the regression analyses, no such association is present for bulk lead concentrations (r=−0.003, 95% CI −0.37–0.36), the most common approach employed in source investigations. In evaluation of the isotopic results on a case by case basis, the strongest associations were for dust wipes and blood. -- Highlights: • Children with elevated blood lead ≥15 µg/dL compared with a group with <10

  16. Lead shot from hunting as a source of lead in human blood

    International Nuclear Information System (INIS)

    Johansen, Poul; Pedersen, Henning Sloth; Asmund, Gert; Riget, Frank

    2006-01-01

    This study investigates the relationship between the intake of birds hunted with lead shot and the lead concentration in human blood. Fifty adult men from Nuuk, Greenland took part in the study. From September 2003 to June 2004 they regularly gave blood samples and recorded how many birds they ate. We found a clear relationship between the number of bird meals and blood lead and also a clear seasonal variation. The concentration was highest in mid-winter when bird consumption is at its highest. Blood lead was low (15 μg/L, mean concentration) among the participants reporting not eating birds. Among those reporting to eat birds regularly, blood lead was significantly higher, up to 128 μg/L (mean concentration). Concentrations depended on the frequency of bird meals: the more the bird meals, the higher the resulting blood lead. This clear relationship points to lead shot as the dominating lead source to people in Greenland. - Birds hunted with lead shot and consumed are a source of lead in human blood

  17. Lead shot from hunting as a source of lead in human blood

    Energy Technology Data Exchange (ETDEWEB)

    Johansen, Poul [National Environmental Research Institute, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: poj@dmu.dk; Pedersen, Henning Sloth [Primary Health Care Center, DK-3900 Nuuk (Greenland); Asmund, Gert [National Environmental Research Institute, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Riget, Frank [National Environmental Research Institute, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)

    2006-07-15

    This study investigates the relationship between the intake of birds hunted with lead shot and the lead concentration in human blood. Fifty adult men from Nuuk, Greenland took part in the study. From September 2003 to June 2004 they regularly gave blood samples and recorded how many birds they ate. We found a clear relationship between the number of bird meals and blood lead and also a clear seasonal variation. The concentration was highest in mid-winter when bird consumption is at its highest. Blood lead was low (15 {mu}g/L, mean concentration) among the participants reporting not eating birds. Among those reporting to eat birds regularly, blood lead was significantly higher, up to 128 {mu}g/L (mean concentration). Concentrations depended on the frequency of bird meals: the more the bird meals, the higher the resulting blood lead. This clear relationship points to lead shot as the dominating lead source to people in Greenland. - Birds hunted with lead shot and consumed are a source of lead in human blood.

  18. Determination of lead in whole blood: Comparison of the LeadCare blood lead testing system with zeeman longitudinal electrothermal atomic absorption spectrometry

    International Nuclear Information System (INIS)

    Pineau, A.; Viallefont, A.; Fauconneau, B.; Rafael, M.; Guillard, O.

    2002-01-01

    This study compares the efficiency of blood lead level analysis by graphite furnace atomic absorption spectrometry (GFAAS) and the portable LeadCare Blood lead testing system (LCS). Recoveries of two added lead concentrations of 22 and 42 μg/dL ranged from 102.4 to 105.5% for LCS and from 96.3 to 97.2% for GFAAS. Measurement of a certified sample (Certified Danish Whole Blood) at a blood lead concentration of 26.2 μg/dL gave within- and between-run coefficients of variation which were both approximately 8% by LCS and 2% by GFAAS. Comparison of the tested method (LCS) versus GFAAS from analysis of 76 samples of blood lead collected from workers in different industrial sectors showed imperfect overall correlation (r = 0.95). The LCS is quite suitable for screening purposes, but requires the use of non-frozen blood collected less than 24 h before. Conservative threshold values should be applied when using the LCS for initial screening in the field. (orig.)

  19. Blood lead and lead-210 origins in residents of Toulouse

    International Nuclear Information System (INIS)

    Servant, J.; Delapart, M.

    1981-01-01

    Blood lead and lead-210 analyses were performed on blood samples from non-smoking residents of Toulouse (city of 400,000 inhabitants). Simultaneous surface soil lead content determinations were carried out by the same procedure on rural zone samples of southwestern France. The observed isotopic ratios were compared in order to evaluate food chain contamination. For an average of 19.7 +- 5.8 μg 100 cc -1 of lead in blood, atmospheric contamination amounts to 20%, estimated as follows: 6% from direct inhalation and 14% from dry deposits on vegetation absorbed as food. The natural levels carried over by the food chain reach 14.9 μg 100 cc -1 and have a 210 Pb/Pb concentration ratio of 0.055 dpmμg -1 . These results lead to a maximum value of 15 μg 100 cc -1 for natural lead in human blood according to the ICRP model. (author)

  20. Multiculturalism and secularism

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2017-01-01

    . Secularism denotes what such principles imply for the relationship between politics and religion. Such formal understandings provide theoretical frameworks for specifying different conceptions of multiculturalism and secularism and for determining in precisely which respects conflicts might arise......Multiculturalism in a European context increasingly has come to denote a concern with religious minorities. Claims for multicultural accommodation of minorities therefore potentially conflict with secularist requirements of separation of politics and religion. Whether there is a conflict depends...... on the general understandings of multiculturalism and secularism. The paper therefore distinguishes and examines different general understandings. Both multiculturalism and secularism can be understood as sets of policies, or as forms of minority accommodation or views about the relationship between religion...

  1. Effect measure modification of blood lead-air lead slope factors.

    Science.gov (United States)

    Richmond-Bryant, Jennifer; Meng, Qingyu; Cohen, Jonathan; Davis, J Allen; Svendsgaard, David; Brown, James S; Tuttle, Lauren; Hubbard, Heidi; Rice, Joann; Kirrane, Ellen; Vinikoor-Imler, Lisa; Kotchmar, Dennis; Hines, Erin; Ross, Mary

    2015-01-01

    There is abundant literature finding that susceptibility factors, including race and ethnicity, age, and housing, directly influence blood lead levels. No study has explored how susceptibility factors influence the blood lead-air lead relationship nationally. The objective is to evaluate whether susceptibility factors act as effect measure modifiers on the blood lead-air lead relationship. Participant level blood lead data from the 1999 to 2008 National Health and Nutrition Examination Survey were merged with air lead data from the US Environmental Protection Agency. Linear mixed effects models were run with and without an air lead interaction term for age group, sex, housing age, or race/ethnicity to determine whether these factors are effect measure modifiers for all ages combined and for five age brackets. Age group and race/ethnicity were determined to be effect measure modifiers in the all-age model and for some age groups. Being a child (1-5, 6-11, and 12-19 years) or of Mexican-American ethnicity increased the effect estimate. Living in older housing (built before 1950) decreased the effect estimate for all models except for the 1-5-year group, where older housing was an effect measure modifier. These results are consistent with the peer-reviewed literature of time-activity patterns, ventilation, and toxicokinetics.

  2. Moderate Secularism and Multicultural Equality

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2008-01-01

    Tariq Modood argues that European states are only ‘moderately secular' and that this kind of secularism is compatible with public accommodation of religious groups and provides a model of Muslim integration appropriate for European states. Although attention to the fact of moderate secularism...... provides a response to a prominent argument against multicultural accommodation of religious minorities, what is really at stake in discussions of multiculturalism and secularism are political principles. Modood's case for accommodation of Muslims along the lines of moderate secularism presupposes...

  3. Temporal stability of blood lead concentrations in adults exposed only to environmental lead

    Energy Technology Data Exchange (ETDEWEB)

    Delves, H T; Sherlock, J C; Quinn, M J

    1984-08-01

    The temporal stability of blood lead concentrations of 21 health adults (14 men and 7 women) exposed only to environmental lead was assessed by analysis of 253 blood specimens collected serially over periods from 7 to 11 months. The women had lower blood lead concentrations (mean 8.5, range 7.4-10.8 micrograms/100 ml) than did the men (mean 12.2, range 8.6-15.8 micrograms/100 ml). These are within the expected ranges for non-occupationally exposed persons. Blood lead concentrations in the serial specimens from both men and women changed very little over the study period, with standard deviations of less than 0.5 micrograms/100 ml for the majority of individual mean concentrations: for all except low subjects the standard deviations were less than 0.8 micrograms/100 ml. Two subjects showed significant changes in blood lead concentrations during the study. A temporary increase in oral lead intake was identified for one of these subjects. In the absence of substantial changes in lead exposure blood lead levels in adults are remarkably stable and for their environmental monitoring a single blood lead concentration is an excellent biological indicator.

  4. geomagnetic secular variation and the 1969–1970 secular jerk

    African Journals Online (AJOL)

    Preferred Customer

    The plots of D rather strongly suggest the presence of a jerk around 1980 at most of the stations. Key words/phrases: Magnetic observatories, polynomial fitting, residuals, secular variation, secular jerk. INTRODUCTION. The magnetic field of the Earth has been observed to exhibit changes of remarkably wide spectral.

  5. Post-Secularism or Liberal-Democratic Constitutionalism?

    NARCIS (Netherlands)

    V. Bader (Veit)

    2012-01-01

    markdownabstract__Abstract__ The increasingly fashionable concept and framing of post-secularism aims to construct simplistic dichotomies and clear-cut ruptures between pre-secular, secular and post-secular ages or epochs, in order to paint generalised and homogenised pictures of societies and

  6. Relationship of blood lead levels to obstetric outcome

    Energy Technology Data Exchange (ETDEWEB)

    Angell, N.F.; Lavery, J.P.

    1982-01-01

    Lead represents a significant environmental hazard to pregnant women and their offspring. Exposure to high environmental levels of lead has been associated with spontaneous abortion, premature rupture of fetal membranes (PROM), and preterm delivery. The relationship between lower exposures and obstetric complications is unknown. The concentration of lead in the blood was measured in 635 specimens of umbilical cord blood collected at delivery. No relationship was found between concentrations of lead in cord blood and the incidence of PROM, preterm delivery, preeclampsia, or meconium staining. Maternal and infant capillary blood was collected 24 hours post partum from 154 of these deliveries. The concentrations of lead in the blood did not vary significantly among cord, infant, and maternal samples, and the three measurements were highly correlated. Levels of zinc protoporphyrin (ZnP) were increased in cord blood as compared with mothers' blood, but no concentration-response relationships between the ratio of cord ZnP to maternal ZnP and lead were found.

  7. Post-Secularism or Liberal-Democratic Constitutionalism?

    NARCIS (Netherlands)

    Bader, V.

    2012-01-01

    The increasingly fashionable concept and framing of post-secularism aims to construct simplistic dichotomies and clear-cut ruptures between pre-secular, secular and post-secular ages or epochs, in order to paint generalised and homogenised pictures of societies and their inevitable evolution. This

  8. The church and the secular: The effect of the post-secular on Christianity

    Directory of Open Access Journals (Sweden)

    Jaco Beyers

    2014-07-01

    Full Text Available Paradigms determine relationships. During the Enlightenment period Emile Durkheim proposed a relationship between the sacred and the profane. Religion, which is concerned with the sacred, was defined in terms of being different from the profane. The profane came to denote the secular. The organic character of religion caused some scholars to predict the end of the church at the hand of modernisation and rationalisation. Some scholars instead envisaged a new form and function of the church. Some scholars anticipated the growth of Christianity. Reality shows that Christianity has not died out but seems to be growing. The new era we are currently in (identified as the postmodern has been described as the post-secular age where a process of re-sacralisation takes place. How will the post-secular influence the church? What will the relationship between the church and the secular be like under a new paradigm? This article suggests that within a postmodern paradigm, the post-secular will emphasise the place of the individual in the church. Fragmentation of society will also be the result of the post-secular. Religiosity in future will have to contend with fundamentalism and civil religion.

  9. Craniofacial Secular Change in Recent Mexican Migrants.

    Science.gov (United States)

    Spradley, Katherine; Stull, Kyra E; Hefner, Joseph T

    2016-01-01

    Research by economists suggests that recent Mexican migrants are better educated and have higher socioeconomic status (SES) than previous migrants. Because factors associated with higher SES and improved education can lead to positive secular changes in overall body form, secular changes in the craniofacial complex were analyzed within a recent migrant group from Mexico. The Mexican group represents individuals in the act of migration, not yet influenced by the American environment, and thus can serve as a starting point for future studies of secular change in this population group. The excavation of a historic Hispanic cemetery in Tucson, Arizona, also allows for a comparison between historic Hispanics and recent migrants to explore craniofacial trends over a broad time period, as both groups originate from Mexico. The present research addresses two main questions: (1) Are cranial secular changes evident in recent Mexican migrants? (2) Are historic Hispanics and recent Mexican migrants similar? By studying secular changes within a migrant population group, secular trends may be detected, which will be important for understanding the biological variation of the migrants themselves and will serve as a preliminary investigation of secular change within Mexican migrants. The comparison of a sample of recent Mexican migrants with a historic Hispanic sample, predominantly of Mexican origin, allows us to explore morphological similarities and differences between early and recent Mexicans within the United States. Vault and face size and a total of 82 craniofacial interlandmark distances were used to explore secular changes within the recent Mexican migrants (females, n = 38; males, n = 178) and to explore the morphological similarities between historic Hispanics (females, n = 54; males, n = 58) and recent migrants. Sexes were separated, and multivariate adaptive regression splines and basis splines (quadratic with one knot) were used to assess the direction and magnitude

  10. BLASPHEMY IN A SECULAR STATE:

    African Journals Online (AJOL)

    MLR

    altogether the religious basis of secular authority'.2 Accordingly, it 'terminated the Pope's claim to universal authority and confirmed the diplomatic independence of secular rulers'.3 However, the meaning of the secular is itself in a continuous state of articulation and re-articulation, casting doubts also on its attributes.

  11. The effect of lead-based paint hazard remediation on blood lead levels of lead poisoned children in New York City.

    Science.gov (United States)

    Leighton, Jessica; Klitzman, Susan; Sedlar, Slavenka; Matte, Thomas; Cohen, Neal L

    2003-07-01

    Despite the widespread use of lead paint hazard control for children with lead poisoning, few controlled studies that estimate the effect of such control on children's blood lead levels have been published. This retrospective follow-up study examined the effects of lead hazard remediation and its timing on the blood lead levels of lead-poisoned children. From the New York City child blood lead registry, 221 children were selected who had an initial blood lead level of 20-44 micro g/dL between 1 July 1994 and 31 December 1996; were 6 months to 6 years of age; had a report of a follow-up blood lead test between 10 and 14 months after the initial test; had a lead-based paint hazard identified in the primary dwelling unit prior to the 10- to 14-month follow-up blood lead test; had resided or spent time at only one address with an identified lead-based paint hazard; and were not chelated. The decline in geometric mean blood lead levels from baseline to 10-14 months later was compared for children whose homes were remediated and whose homes were not remediated during the follow-up period. Regardless of remediation, geometric mean blood lead levels declined significantly from 24.3 micro g/dL at the initial diagnosis to 12.3 micro g/dL at the 10- to 14-month follow-up blood lead test (Premediated the geometric mean blood lead levels declined 53% compared to 41% among the 75 children whose homes were not remediated by the follow-up blood lead test, a remediation effect of approximately 20% (Premediation effect was 11%, although it was no longer significant. Race was the only factor that appeared to confound the relationship: Black children had higher follow-up blood lead levels even after controlling for other factors, including the natural logarithm of the initial blood lead level. The effect of remediation appeared to be stronger for younger (10 to remediation (within less than 3 months) appeared to have greater declines in blood lead levels at the follow-up test than

  12. The Incidence and Management of Conflicts in Secular and Non-Secular Tertiary Institutions in South West Nigeria

    Science.gov (United States)

    Ayodele, Joseph Babatola; Adewumi, Joseph Olukayode

    2007-01-01

    This paper compared the incidence and management of conflicts in secular and non-secular tertiary institutions in Nigeria. The sample of this study was made of sixty staff, and two hundred and forty students randomly selected each from two secular and two non-secular tertiary institutions in south western Nigeria. A validated questionnaire was…

  13. The effect of interior lead hazard controls on children's blood lead concentrations: a systematic evaluation.

    Science.gov (United States)

    Haynes, Erin; Lanphear, Bruce P; Tohn, Ellen; Farr, Nick; Rhoads, George G

    2002-01-01

    Dust control is often recommended to prevent children's exposure to residential lead hazards, but the effect of these controls on children's blood lead concentrations is uncertain. We conducted a systematic review of randomized, controlled trials of low-cost, lead hazard control interventions to determine the effect of lead hazard control on children's blood lead concentration. Four trials met the inclusion criteria. We examined mean blood lead concentration and elevated blood lead concentrations (> or = 10 microg/dL, > or = 15 microg/dL, and > or = 20 microg/dL) and found no significant differences in mean change in blood lead concentration for children by random group assignment (children assigned to the intervention group compared with those assigned to the control group). We found no significant difference between the intervention and control groups in the percentage of children with blood lead > or = 10 microg/dL, 29% versus 32% [odds ratio (OR), 0.85; 95% confidence interval (CI), 0.56-1.3], but there was a significant difference in the percentage of children with blood lead > or = 15 microg/dL between the intervention and control groups, 6% versus 14% (OR, 0.40; 95% CI, 0.21-0.80) and in the percentage of children with blood lead > or = 20 microg/dL between the intervention and control groups, 2% versus 6% (OR, 0.29; 95% CI, 0.10-0.85). We conclude that although low-cost, interior lead hazard control was associated with 50% or greater reduction in the proportion of children who had blood lead concentrations exceeding 15 microg/dL and > or = 20 microg/dL, there was no substantial effect on mean blood lead concentration.

  14. HAS ROMANIA BECOME A SECULAR SOCIETY?

    Directory of Open Access Journals (Sweden)

    IRINA STAHL

    2016-04-01

    Full Text Available The article examines the question of secularization of Europe, and in particular of Romania, by using multiple international data sets. Secularization has been defined separation of the state government and religious authority resulting in a decrease in church attendance, a diminished trust in religious institutions, a lessening of religions’ importance in society, an increase in religious diversity with a concomitant decrease in group cohesiveness, and the rise of situational ethics and moral relativism. Several theories of secularization are explored in an effort to determine the presence of a secular continuum. Although there may be an increase of secular behaviours in member states of the European Union, a claim of growing secularism in Romania is not supported by an examination of the multiple data sets

  15. The effect of lead-based paint hazard remediation on blood lead levels of lead poisoned children in New York City

    International Nuclear Information System (INIS)

    Leighton, Jessica; Klitzman, Susan; Sedlar, Slavenka; Matte, Thomas; Cohen, Neal L.

    2003-01-01

    Despite the widespread use of lead paint hazard control for children with lead poisoning, few controlled studies that estimate the effect of such control on children's blood lead levels have been published. This retrospective follow-up study examined the effects of lead hazard remediation and its timing on the blood lead levels of lead-poisoned children. From the New York City child blood lead registry, 221 children were selected who had an initial blood lead level of 20-44 μg/dL between 1 July 1994 and 31 December 1996; were 6 months to 6 years of age; had a report of a follow-up blood lead test between 10 and 14 months after the initial test; had a lead-based paint hazard identified in the primary dwelling unit prior to the 10- to 14-month follow-up blood lead test; had resided or spent time at only one address with an identified lead-based paint hazard; and were not chelated. The decline in geometric mean blood lead levels from baseline to 10-14 months later was compared for children whose homes were remediated and whose homes were not remediated during the follow-up period. Regardless of remediation, geometric mean blood lead levels declined significantly from 24.3 μg/dL at the initial diagnosis to 12.3 μg/dL at the 10- to 14-month follow-up blood lead test (P<0.01). Among the 146 children whose homes were remediated the geometric mean blood lead levels declined 53% compared to 41% among the 75 children whose homes were not remediated by the follow-up blood lead test, a remediation effect of approximately 20% (P<0.01). After adjusting for potential confounders, the remediation effect was 11%, although it was no longer significant. Race was the only factor that appeared to confound the relationship: Black children had higher follow-up blood lead levels even after controlling for other factors, including the natural logarithm of the initial blood lead level. The effect of remediation appeared to be stronger for younger (10 to <36 months old) than for older (36

  16. Relationship between blood lead, blood pressure, stroke, and heart attacks in middle-aged British men

    International Nuclear Information System (INIS)

    Pocock, S.J.; Shaper, A.G.; Ashby, D.; Delves, H.T.; Clayton, B.E.

    1988-01-01

    The relationship between blood lead concentration and blood pressure is examined in a survey of 7371 men aged 40 to 59 from 24 British towns. After allowance for relevant confounding variables, including town of residence and alcohol consumption, there exists a very weak but statistically significant positive association between blood lead and both systolic and diastolic blood pressure. After 6 years of follow-up, 316 of these men had major ischemic heart disease, and 66 had a stroke. After allowance for the confounding effects of cigarette smoking and town of residence there is no evidence that blood lead is a risk factor for these cardiovascular events. However, as the blood lead-blood pressure association is so weak, it is unlikely that any consequent association between lead and cardiovascular disease could be demonstrated from prospective epidemiological studies. An overview of data from this and other large epidemiological surveys provides reasonable consistent evidence on lead and blood pressure. While NHANES II data on 2254 US men indicate a slightly stronger association between blood lead and systolic blood pressure, data from two Welsh studies on over 2000 men did not show a statistically significant association. Nevertheless, such statistical association cannot be taken as establishing a causal effect of low-level lead exposure on blood pressure

  17. Consumption of lead-shot cervid meat and blood lead concentrations in a group of adult Norwegians.

    Science.gov (United States)

    Meltzer, H M; Dahl, H; Brantsæter, A L; Birgisdottir, B E; Knutsen, H K; Bernhoft, A; Oftedal, B; Lande, U S; Alexander, J; Haugen, M; Ydersbond, T A

    2013-11-01

    Several recent investigations have reported high concentrations of lead in samples of minced cervid meat. This paper describes findings from a Norwegian study performed in 2012 among 147 adults with a wide range of cervid game consumption. The main aim was to assess whether high consumption of lead-shot cervid meat is associated with increased concentration of lead in blood. A second aim was to investigate to what extent factors apart from game consumption explain observed variability in blood lead levels. Median (5 and 95 percentile) blood concentration of lead was 16.6 µg/L (7.5 and 39 µg/L). An optimal multivariate linear regression model for log-transformed blood lead indicated that cervid game meat consumption once a month or more was associated with approximately 31% increase in blood lead concentrations. The increase seemed to be mostly associated with consumption of minced cervid meat, particularly purchased minced meat. However, many participants with high and long-lasting game meat intake had low blood lead concentrations. Cervid meat together with number of bullet shots per year, years with game consumption, self-assembly of bullets, wine consumption and smoking jointly accounted for approximately 25% of the variation in blood lead concentrations, while age and sex accounted for 27% of the variance. Blood lead concentrations increased approximately 18% per decade of age, and men had on average 30% higher blood lead concentrations than women. Hunters who assembled their own ammunition had 52% higher blood lead concentrations than persons not making ammunition. In conjunction with minced cervid meat, wine intake was significantly associated with increased blood lead. Our results indicate that hunting practices such as use of lead-based ammunition, self-assembling of lead containing bullets and inclusion of lead-contaminated meat for mincing to a large extent determine the exposure to lead from cervid game consumption. © 2013 Elsevier Inc. All rights

  18. Letter to editor: Blood pressure, hypertension and lead exposure.

    Science.gov (United States)

    Yang, Wen-Yi; Staessen, Jan A

    2018-02-19

    A significant association of office diastolic blood pressure with low-level blood lead exposure was reported in a Brazilian adult population. However, caution should be taken to interpret these results. The multivariable-adjusted association with blood pressure was positive for diastolic blood pressure, but inverse for systolic blood pressure. The association sizes were infinitesimal without clinical relevance. The outcome measures, i.e. blood pressure and the prevalence of hypertension were analysed across categories of the blood lead distribution - not in relation to blood lead as continuous variable. Blood pressure was the average of two oscillometric office readings, whereas ambulatory monitoring is the state-of-the-art.

  19. Children’s Blood Lead Seasonality in Flint, Michigan (USA), and Soil-Sourced Lead Hazard Risks

    Science.gov (United States)

    Laidlaw, Mark A.S.; Filippelli, Gabriel M.; Sadler, Richard C.; Gonzales, Christopher R.; Ball, Andrew S.; Mielke, Howard W.

    2016-01-01

    In Flint; MI; USA; a public health crisis resulted from the switching of the water supply from Lake Huron to a more corrosive source from the Flint River in April 2014; which caused lead to leach from water lines. Between 2010 and 2015; Flint area children’s average blood lead patterns display consistent peaks in the third quarter of the year. The third quarter blood lead peaks displayed a declining trend between 2010 and 2013; then rose abruptly between the third quarters of 2013 from 3.6% blood lead levels ≥5 µg/dL to a peak of about 7% in the third quarter of 2014; an increase of approximately 50%. The percentage of blood lead level ≥5 µg/dL in the first quarter of 2015 then dropped to 2.3%; which was the same percentage as the first quarter of 2014 (prior to the Flint River water source change). The Flint quarterly blood lead level peak then rose to about 6% blood lead levels ≥ 5 µg/dL in the third quarter of 2015; and then declined to about 2.5% in the fourth quarter of 2015. Soil lead data collected by Edible Flint food collaborative reveal generally higher soil lead values in the metropolitan center for Flint; with lower values in the outskirts of the city. The questions that are not being asked is why did children’s blood lead levels display a seasonal blood lead pattern before the introduction of the new water supply in Flint; and what are the implications of these seasonal blood lead patterns? Based upon previous findings in Detroit and other North American cities we infer that resuspension to the air of lead in the form of dust from lead contaminated soils in Flint appears to be a persistent contribution to lead exposure of Flint children even before the change in the water supply from Lake Huron to the Flint River. PMID:27023578

  20. An examination of blood lead levels in thai nielloware workers.

    Science.gov (United States)

    Decharat, Somsiri; Kongtip, Pornpimol; Thampoophasiam, Prapin; Thetkathuek, Anamai

    2012-09-01

    The objectives of this study were to determine the lead levels in blood samples from nielloware workers, to determine airborne lead levels, to describe the workers' hygiene behaviors, and to ascertain and describe any correlations between lead levels in blood samples and lead levels in airborne samples. Blood samples and airborne samples from 45 nielloware workers were collected from nielloware workplaces in Nakhon Sri Thammarat Province, Thailand. Lead levels were determined by flame atomic absorption spectrometry (FAAS), at a wavelength of 283.3 nm. FAAS was used especially adequate for metals at relatively high concentration levels. The geometric mean of the 45 airborne lead levels was 81.14 µg/m(3) (range 9.0-677.2 µg/m(3)). The geometric mean blood lead level of the 45 workers was 16.25 µg/dL (range 4.59-39.33 µg/dL). No worker had a blood lead level > 60 µg/dL. A statistically significantly positive correlation was found between airborne lead level and blood lead levels (r = 0.747, p lead levels (p leads and airborne lead levels.

  1. Environmental lead exposure among preschool children in Shanghai, China: blood lead levels and risk factors.

    Directory of Open Access Journals (Sweden)

    Jia Cao

    Full Text Available OBJECTIVE: To determine blood lead levels and to identify related risk factors among children in Shanghai; to explore the lead change trend of children after industrial transformation and to provide data for policy development to control environmental lead pollution in Shanghai. METHODS: A stratified-clustered-random sampling method was used. A tungsten atomizer absorption spectrophotometer was employed to determine blood lead levels. RESULTS: The arithmetic mean, geometric mean and median of blood lead levels of 0- to 6-year-old children from Shanghai were 22.49 µg/L, 19.65 µg/L and 19.5 µg/L, including 0.26% (6/2291 with concentrations ≥100 µg/L and 2.7% (61/2291 with concentrations ≥50 µg/L. Boys' levels (23.57 µg/L were greater than those of girls (21.2 µg/L. The blood lead levels increased with age. This survey showed that the Chongming district was the highest and Yangpu district was the lowest, this result is completely opposite with the earlier survey in Shanghai. Risk factors for lead contamination included housing environment, parents' education levels, social status, hobbies, and children's nutritional status. CONCLUSIONS: The blood lead levels of children in Shanghai were lower than the earlier data of Shanghai and those of published studies in China, but higher than the blood lead levels of developed countries. The blood lead levels of urban districts are higher than the central districts with the industrial transformation. Society and the government should take an active interest in childhood lead poisoning of urban areas.

  2. Relationship of blood lead levels and blood pressure in NHANES II: additional calculations

    International Nuclear Information System (INIS)

    Gartside, P.S.

    1988-01-01

    In performing research for associations and relationships among the data thus far published from the NHANES II survey, only the data for the 64 communities involved may be used. The simple omission of a few essential data makes impossible any valid analysis from the data for the 20,325 individual respondents. In this research for associations between blood lead levels and blood pressure in NHANES II, the method of forward stepwise regression was used. This avoids the problem of inflated error rates for blood lead, maximizes the number of data analyzed, and minimizes the number of independent variables entered into the regression model, thus avoiding the pitfalls that previous NHANES II research of blood lead and blood pressure has fallen into when using backward stepwise regression. The results of this research for white male adults, white female adults, and black adults were contradictory and lacked consistency and reliability. In addition, the overall average association between blood lead level and blood pressure was so minute that the only rational conclusion is that there is no evidence for this association to be found in the NHANES II data

  3. Blood lead and carboxyhemoglobin levels in chainsaw operators.

    Science.gov (United States)

    van Netten, C; Brubaker, R L; Mackenzie, C J; Godolphin, W J

    1987-06-01

    Fallers in the British Columbia west coast lumber industry often work in climatic and local conditions where little ventilation in their immediate environment is possible. Under these conditions carbon monoxide (CO) and lead fumes from exhaust gases could build up and become a serious occupational hazard. This study monitored the environmental exposure of six fallers to carbon monoxide, nitrogen oxides, and lead under conditions where buildup of these agents would be expected. At the same time blood samples were taken to correlate these environmental concentrations to carboxyhemoglobin (COHb) and blood lead levels. Although there was a highly significant difference between the fallers and the controls regarding the exposure to CO and lead as well as their corresponding COHb and blood lead levels, the environmental and blood concentration of the agents in question did not exceed the maximum allowable concentrations. Temporary short fluctuations in carboxyhemoglobin levels were not monitored in this study and cannot be ruled out as a potential occupational hazard.

  4. Blood lead and carboxyhemoglobin levels in chainsaw operators

    Energy Technology Data Exchange (ETDEWEB)

    van Netten, C.; Brubaker, R.L.; Mackenzie, C.J.; Godolphin, W.J.

    1987-06-01

    Fallers in the British Columbia west coast lumber industry often work in climatic and local conditions where little ventilation in their immediate environment is possible. Under these conditions carbon monoxide (CO) and lead fumes from exhaust gases could build up and become a serious occupational hazard. This study monitored the environmental exposure of six fallers to carbon monoxide, nitrogen oxides, and lead under conditions where buildup of these agents would be expected. At the same time blood samples were taken to correlate these environmental concentrations to carboxyhemoglobin (COHb) and blood lead levels. Although there was a highly significant difference between the fallers and the controls regarding the exposure to CO and lead as well as their corresponding COHb and blood lead levels, the environmental and blood concentration of the agents in question did not exceed the maximum allowable concentrations. Temporary short fluctuations in carboxyhemoglobin levels were not monitored in this study and cannot be ruled out as a potential occupational hazard.

  5. Fuzzy Law and the Boundaries of Secularism

    Directory of Open Access Journals (Sweden)

    W Menski

    2010-12-01

    Full Text Available The author delivered a speech at a Religare Conference. Showing his distaste for fuzzy law, he argues that "moderate secularism" is not merely another fuzzy concept, but it is "super-fuzzy", and that lawyers claiming to love certainty "have a tendency to sit in judgment over matters and even pre-judge things they know little about, including legal pluralism" leading to much irritation.

  6. Secular change of LOD caused by core evolution

    Science.gov (United States)

    Denis, C.; Rybicki, K. R.; Varga, P.

    2003-04-01

    Fossils and tidal deposits suggest that, on the average, the Earth's despinning rate had been five times less in the Proterozoic than in the Phanerozoic. This difference is probably due, for the major part, to the existence of a Proterozoic supercontinent. Nevertheless, core formation and core evolution should have compensated to some extent the effect of tidal friction, by diminishing the Earth's inertia moment. We have investigated quantitatively this contribution of the evolving core to the change of LOD. For the present epoch, we find that the solidification of the inner core causes a relative secular decrease of LOD of approximately 3 μs per century, whereas the macrodiffusion of iron oxides and sulfides from the D" into the outer core across the CMB (inasfar as Majewski's theory holds) leads to a relative secular decrease of LOD by about 15 μs per century. On the other hand, the theory of slow core formation developped by Runcorn in the early 1960s as a by-product of his theory of mantle-wide convection, leads to a relative secular decrease of LOD during most of the Proterozoic of about 0.25 ms per century. Although core formation is now widely assumed to have been a thermal run-away process that occurred shortly after the Earth itself had formed, Runcorn's theory of the growing core would nicely explain the observed palaeo-LOD curve. In any case, formation of the core implies, all in all, a relative decrease of LOD of typically 3 hours.

  7. Blood harmane, blood lead, and severity of hand tremor: evidence of additive effects.

    Science.gov (United States)

    Louis, Elan D; Factor-Litvak, Pam; Gerbin, Marina; Slavkovich, Vesna; Graziano, Joseph H; Jiang, Wendy; Zheng, Wei

    2011-03-01

    Tremor is a widespread phenomenon in human populations. Environmental factors are likely to play an etiological role. Harmane (1-methyl-9H-pyrido[3,4-β]indole) is a potent tremor-producing β-carboline alkaloid. Lead is another tremor-producing neurotoxicant. The effects of harmane and lead with respect to tremor have been studied in isolation. We tested the hypothesis that tremor would be particularly severe among individuals who had high blood concentrations of both of these toxicants. Blood concentrations of harmane and lead were each quantified in 257 individuals (106 essential tremor cases and 151 controls) enrolled in an environmental epidemiological study. Total tremor score (range = 0-36) was a clinical measure of tremor severity. The total tremor score ranged from 0 to 36, indicating that a full spectrum of tremor severities was captured in our sample. Blood harmane concentration correlated with total tremor score (p = 0.007), as did blood lead concentration (p = 0.045). The total tremor score was lowest in participants with both low blood harmane and lead concentrations (8.4 ± 8.2), intermediate in participants with high concentrations of either toxicant (10.5 ± 9.8), and highest in participants with high concentrations of both toxicants (13.7 ± 10.4) (p=0.01). Blood harmane and lead concentrations separately correlated with total tremor scores. Participants with high blood concentrations of both toxicants had the highest tremor scores, suggesting an additive effect of these toxicants on tremor severity. Given the very high population prevalence of tremor disorders, identifying environmental determinants is important for primary disease prevention. Copyright © 2010 Elsevier Inc. All rights reserved.

  8. Factors Associated With Elevated Blood Lead Levels in Children.

    Science.gov (United States)

    Chaudhary, Sakshi; Firdaus, Uzma; Ali, Syed Manazir; Mahdi, Abbas Ali

    2018-01-15

    To determine the prevalence and correlates of elevated blood lead level in children (6-144 months) of Aligarh. A hospital-based cross-sectional study was conducted. Venous blood was obtained for lead estimation and a structured questionnaire was filled. A total of 260 children were enrolled. The prevalence of elevated blood lead level was 44.2%, seen mostly in children below 5 years of age. Old and deteriorating wall paints at home was found to be significantly associated with elevated levels. Lead-based house paints are potential source of lead exposure. Meticulous renovation and painting of the walls with safe paints is desirable.

  9. Post-secular religious practices entering traditional religion

    Directory of Open Access Journals (Sweden)

    Urszula Pękala

    2012-01-01

    Full Text Available Nowadays we can observe complex interactions between the religious and secular spheres. Several different processes take place simultaneously: the traditionally religious elements function in the secular sphere as if they were part of secular culture; elements of the secular sphere build a specific kind of post-secular religiosity; finally, this post-secular religiosity influences traditional religions. This article focuses on the last stage of these changes. The author's purpose is to describe and interpret the practices we can observe. Because of the complexity of this issue, the analyses are limited to examples taken from the Catholic Church in Germany, where this process seems to be as popular as it is paradoxical. Catholicism realises that the post-secular forms of religiosity are very popular and that many people choose them instead of the traditional Church. It could offer them spirituality based on ages of experience. But instead of making its own spiritual tradition competitive on the spiritual market, Catholicism seems to offer Christianised post-secular goods, or its own traditional elements represented in a secularised form. It seems difficult to predict how it will all end. However, we observe an interesting encounter and interaction between an ‘old’ religion and a new religiosity, which will certainly have impact on further presence of the Church in the society.

  10. Research on meaning-making and health in secular society: Secular, spiritual and religious existential orientations

    DEFF Research Database (Denmark)

    Hvidt, Niels Christian; La Cour, Peter

    2010-01-01

    cultural basis for research in secular society. Reviewing the literature, three main domains of existential meaning-making emerge: Secular, spiritual, and religious. In reconfirming these three domains, we propose to couple them with the three dimensions of cognition (knowing), practice (doing...

  11. Religious Globalisms in the Post-Secular Age

    NARCIS (Netherlands)

    Wilson, E.K.; B. Steger, Manfred

    2013-01-01

    This article explores the interconnections between mounting global crises and the emergence of the post-secular. Specifically, the article argues that the post-secular is both a description of and a response to shifting global realities in the twenty-first century. It describes the crisis of secular

  12. An Examination of Blood Lead Levels in Thai Nielloware Workers

    OpenAIRE

    Decharat, Somsiri; Kongtip, Pornpimol; Thampoophasiam, Prapin; Thetkathuek, Anamai

    2012-01-01

    Objectives: The objectives of this study were to determine the lead levels in blood samples from nielloware workers, to determine airborne lead levels, to describe the workers’ hygiene behaviors, and to ascertain and describe any correlations between lead levels in blood samples and lead levels in airborne samples. Methods: Blood samples and airborne samples from 45 nielloware workers were collected from nielloware workplaces in Nakhon Sri Thammarat Province, Thailand. Lead levels were det...

  13. Blood lead levels in preschool children in Cape Town

    Energy Technology Data Exchange (ETDEWEB)

    Deveaux, P.; Kibel, M.A.; Dempster, W.S.; Pocock, F.; Formenti, K.

    1986-03-29

    Blood lead levels were assessed in 293 children aged between 4 and 6 years attending preschool centers in metropolitan Cape Town in order to establish the degree of lead absorption. Anthropometric data, blood count, zinc protoporphyrin and blood lead level were obtained for each child. A questionnaire was used to determine socio-economic status, dietary habits and history of pica. Thirteen children, or 4,4% of those sampled, had blood levels of greater than or equal to 30 micrograms/dl. The majority of these children lived in close proximity to one another in a socially deprived inner urban environment. Environmental sampling for lead was carried out in the homes of children with the highest blood levels as well as in the homes of a matched control group with low levels living in the same area. The only difference was a significantly higher incidence of pica in the children with high levels.

  14. Elevated blood lead levels associated with illegally distilled alcohol.

    Science.gov (United States)

    Pegues, D A; Hughes, B J; Woernle, C H

    1993-06-28

    Whiskey produced in illegal stills (ie, "moonshine") remains an important and underappreciated source of lead toxicity in some rural counties of the Southeast. From March 5 through October 26, 1991, eight adult patients with elevated blood lead levels were identified at a rural county hospital in Alabama and were reported to the Alabama Department of Public Health notifiable disease surveillance system. A case-patient was defined as any person 17 years of age or more who presented to the hospital from January 1, 1990, through December 31, 1991, and had a blood lead level of 0.72 mumol/L or more (15 micrograms/dL or more). To identify cases and potential sources of lead exposure, we reviewed medical and laboratory records from the hospital, interviewed patients with elevated blood lead levels, and determined the lead content of moonshine samples. Nine patients met the case definition, including one patient who was not reported to the state. Patients ranged in age from 28 to 62 years; blood lead values ranged from 0.77 to 12.50 mumol/L (16 to 259 micrograms/dL). The most frequent signs of possible lead toxicity included seizures (six), microcytic anemia (five), and encephalopathy (two); one patient died. The only identified source of lead exposure for the nine patients was moonshine ingestion. Moonshine samples available from local stills contained sufficient amounts of lead (340 to 4600 mumol/L) to result in the observed blood lead levels. This investigation emphasizes the adverse health effects and ongoing public health impact of moonshine ingestion.

  15. Blood Lead Levels and Risk Factors among Preschool Children in a Lead Polluted Area in Taizhou, China

    Directory of Open Access Journals (Sweden)

    Zhenyan Gao

    2017-01-01

    Full Text Available Objective. To determine the blood lead levels and identify related risk factors among preschool children in a lead polluted area (Taizhou, China and provide theoretical support for prevention of lead pollution. Methods. A stratified-clustered-random sampling method was used to determine the survey sample. Blood lead levels were determined by the tungsten atomizer absorption spectrophotometer. Results. A total of 2,018 subjects (average age of 59 months; 1,087 boys and 931 girls were included. The arithmetic mean, geometric mean, and median blood lead levels of the preschool children were 56.4 μg/L, 48.9 μg/L, and 46 μg/L. A total of 8.8% children had blood lead levels >100 μg/L and 43.9% had blood lead levels >50 μg/L. Mother’s education level, father’s occupation, decorative tableware, exposure to makeup, and the residential floor were all risk factors for elevated blood lead levels (odds ratios of 1.42, 1.21, 1.11, 1.19, and 1.27, resp., while hand washing before eating food was a protective factor (odds ratio of 0.88. Conclusions. The blood lead levels of preschool children in Taizhou were higher than in other areas in China and in developed countries. Therefore, policies ensuring lead-based industries are not placed in close proximity to residential areas are required.

  16. Out of time : the limits of secular critique

    Directory of Open Access Journals (Sweden)

    Randell-Moon, Holly

    2011-01-01

    Full Text Available A review of Talal Asad, Wendy Brown, Judith Butler, Saba Mahmood, 'Is critique secular? Blasphemy, injury, and free speech' and Michael Warner, Jonathan Vanantwerpen, and Craig Calhoun (eds, 'Varieties of secularism in a secular age'.

  17. Thinking beyond Secularism: The Catholic Church and Political Practice in Rural South India

    Directory of Open Access Journals (Sweden)

    Aparna Sundar

    2012-04-01

    Full Text Available This article re-opens the debate on secularism in India by looking at a religion and a region that has historically been marginal to this discourse, focusing on the way in which the Catholic Church has historically mediated the relationship between individuals and the state, among the fishing communities of South India. The Catholic Church’s dominant position among the fishing communities, its minority status within India, as well as theological and other shifts that have taken place within the global Church, lead it to articulate a secular, even radical politics as its primary mode of religious engagement. Radical clergy, many from fishing backgrounds, act as both organic and traditional intellectuals in the Gramscian sense, linking the traditional religious concerns of the Church to the secular interests of their parishioners. Likewise, villagers participate in Church-generated associations spaces to secure wider political goals. The paper concludes that certain forms of religious organisation in the public sphere might indeed be compatible with democracy, citizenship, and even secularism.

  18. Lead poisoning and the blood-brain barrier

    International Nuclear Information System (INIS)

    Hertz, M.H.; Bolwig, T.G.; Grandjean, P.; Westergaard, E.

    1981-01-01

    Lead exposure may produce varying degrees of neuropsychiatric manifestations from discrete phenomena, quite often seen in children and as an occupational disease, to the rare fulminant lead encephalopathy. It was determined whether or not damage of the blood-brain barrier permeability in adult rats, as has been demonstr rated in neonatal animals exposed to lead, could also play a role. Massive lead exposure did not induce any change in the transfer (facilitated diffusion) of phenylalanine and tyrosine measured by means of the indicator dilution technique. Ultrastructural examination, after application of horseradish peroxidase, did not reveal any pahtological changes in the permeability to the tracer. It is concluded that in adult rats, in contrast to neonatal anmials, the observed pathological signs clearly seen in the chronically exposed animals must be ascribed to a noxious influence of lead on the extravascular side of the blood-brain barrier. (author)

  19. Atmospheric lead as indicator of children's blood lead in Mumbai India

    Science.gov (United States)

    Tripathi, R. M.; Raghunath, R.; Sadasivan, S.; Puranik, V. D.

    2003-05-01

    Average concentration of Pb in air particulates in different suburbs of Mumbai during 1998-2001 varied between 0.11 and 0.35 μg m^{-3}. The concentration of Pb in all the residential suburban atmosphere is well below the Central Pollution Control Board (CPCB, 1994) prescribed limit of 1 μg m^{-3}. The daily intake Pb for Mumbai children through ingestion was found to vary from 13.9-18.9 μg. The concentrations of Pb in blood of 6-lOy old children residing in different suburbs of Mumbai were found to vary from 8.3 to 9.8 μg dl^{-l}. The correlation between blood lead of children and air lead reveals that the blood Pb level in children could increase by 3.52 μg dl^{-1} for an incremental rise of 1.0 μg m^{-3} of air Pb concentration.

  20. Blood Lead Toxicity Analysis of Multipurpose Canines and Military Working Dogs.

    Science.gov (United States)

    Reid, Paul; George, Clinton; Byrd, Christopher M; Miller, Laura; Lee, Stephen J; Motsinger-Reif, Alison; Breen, Matthew; Hayduk, Daniel W

    Special Operations Forces and their accompanying tactical multipurpose canines (MPCs) who are involved in repeated live-fire exercises and military operations have the potential for increased blood lead levels and toxicity due to aerosolized and environmental lead debris. Clinical lead-toxicity symptoms can mimic other medical disorders, rendering accurate diagnosis more challenging. The objective of this study was to examine baseline lead levels of MPCs exposed to indoor firing ranges compared with those of nontactical military working dogs (MWDs) with limited or no exposure to the same environment. In the second part of the study, results of a commercially available, human-blood lead testing system were compared with those of a benchtop inductively coupled plasma-mass spectrometry (ICP-MS) analysis technique. Blood samples from 18 MPCs were tested during routine clinical blood draws, and six samples from a canine group with limited exposure to environmental lead (nontactical MWDs) were tested for comparison. There was a high correlation between results of the commercial blood-testing system compared with ICP-MS when blood lead levels were higher than 4.0µg/dL. Both testing methods recorded higher blood lead levels in the MPC blood samples than in those of the nontactical MWDs, although none of the MPC samples tested contained lead levels approaching those at which symptoms of lead toxicity have previously been reported in animals (i.e., 35µg/dL). 2018.

  1. Occurrence and determinants of increases in blood lead levels in children shortly after lead hazard control activities

    International Nuclear Information System (INIS)

    Clark, Scott; Grote, JoAnn; Wilson, Jonathan; Succop, Paul; Chen Mei; Galke, Warren; McLaine, Pat

    2004-01-01

    This study is an examination of the effect of lead hazard control strategies on children's blood lead levels immediately after an intervention was conducted as part of the US Department of Housing and Urban Development's Lead-Based Paint Hazard Control Grant Program. Fourteen state and local government grantees participated in the evaluation. The findings indicated an overall average reduction in the blood lead levels of 869 children soon after the implementation of lead hazard controls. However, 9.3% of these children (n=81) had blood lead increases of 5 μg/dL or more. Data routinely collected as part of the evaluation, as well as additional information supplied by the individual programs, were used to determine potential reasons for these observed increases in blood lead. A logistic regression analysis indicated that three principal factors were associated with the blood lead increases: the number of exterior deteriorations present in the child's home (prior to intervention), the educational level of the female parent or guardian of the child, and the child's age. The statistical analysis did not find evidence that children living in households that either did not relocate or relocated for less than the full work period were significantly more likely to have a blood lead increase equal to or greater than 5 μg/dL than children living in households that fully relocated. Statistical analyses also did not reveal any single interior strategy to be more or less likely than others to be associated with a blood lead increase of 5 μg/dL or more

  2. In vivo x-ray fluorescence of bone lead in the study of human lead metabolism: Serum lead, whole blood lead, bone lead, and cumulative exposure

    International Nuclear Information System (INIS)

    Cake, K.M.; Chettle, D.R.; Webber, C.E.; Gordon, C.L.

    1995-01-01

    Traditionally, clinical studies of lead's effect on health have relied on blood lead levels to indicate lead exposure. However, this is unsatisfactory because blood lead levels have a half-life of approximately 5 weeks, and thus reflect recent exposure. Over 90% of the lead body burden is in bone, and it is thought to have a long residence time, thus implying that measurements of bone lead reflect cumulative exposure. So, measurements of bone lead are useful in understanding the long-term health effects of lead. Ahlgren reported the first noninvasive measurements of bone lead in humans, where γ-rays from 57 Co were used to excite the K series x-rays of lead. The lead detection system at McMaster University uses a 109 Cd source which is positioned at the center of the detector face (HPGe) and a near backscatter (∼160 degrees) geometry. This arrangement allows great flexibility, since one can sample lead in a range of different bone sites due to a robust normalization technique which eliminates the need to correct for bone geometry, thickness of overlying tissue, and other related factors. The effective radiation dose to an adult during an x-ray fluorescence bone lead measurement is extremely low, being 35 nSv. This paper addresses the issue of how bone, whole blood, and serum lead concentrations can be related in order to understand a person's lead exposure history

  3. The Coming of Secular Buddhism: a Synoptic View

    Directory of Open Access Journals (Sweden)

    Winton Higgins

    2015-02-01

    Full Text Available Secular Buddhism is coalescing today in response to two main factors. First, it rejects the incoherence of Buddhist modernism, a protean formation that accommodates elements as far afield as ancestral Buddhism and psychotherapies claiming the Buddhist brand. Second, it absorbs the cultural influence of modern secularity in the West. Historically understood, secularity has constituted a centuries-long religious development, not a victory of "science" over "religion." Today's secularity marks a further stage in the cultural decline of "enchanted" truth-claims and the intellectual eclipse of metaphysics, especially under the aegis of phenomenology. In Buddhism as in Christianity, secularity brings forth a new humanistic approach to ethical-spiritual life and creative this-worldly practices.

  4. Both physiology and epidemiology support zero tolerable blood lead levels.

    Science.gov (United States)

    Shefa, Syeda T; Héroux, Paul

    2017-10-05

    Inorganic lead is one of the most common causes of environmental metal poisonings, and its adverse effects on multiple body systems are of great concern. The brain, along with the kidneys, are critically susceptible to lead toxicity for their hosting of high affinity lead binding proteins, and very sensitive physiology. Prolonged low-lead exposure frequently remains unrecognized, causes subtle changes in these organ systems, and manifests later at an irreversible stage. With the repeated documentation of "no safe blood lead level", the pernicious effects of lead at any measurable concentration need to be emphasized. In this review, we surveyed articles on chronic low-level lead exposures with a blood lead concentrations lead on both nervous and renal systems were obvious at a blood lead concentration of 2μg/dL, with the absence of any detectable threshold. The deleterious effect of lead on two different organ systems at such low concentrations drew our attention to the various extracellular and intracellular events that might be affected by minimal concentration of body lead, especially blood lead. Is there a true common ground between low-level lead toxicity in both the nervous system and the kidney? Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Umbilical Cord Blood Lead Levels and Neonatal Behaviour

    Directory of Open Access Journals (Sweden)

    M. L. de Cáceres

    1995-01-01

    Full Text Available Negative correlations have been found between cord blood lead levels and scores on the Brazelton Neonatal Behaviour Assessment in 30 otherwise healthy newborns. Items in the Habituation, Orientation and Regulation of state clusters, particularly those items related to self-regulatory, self-quieting and auditory habituation, showed lower scores (worse performance in those newborns with higher cord blood lead levels. These disturbances are potentially important since this type of behavior may interfere with the normal process of adaptation to their environment, leading to a less than optimal bonding between newborns and their carers.

  6. Secular humanism and "scientific psychiatry"

    Directory of Open Access Journals (Sweden)

    Szasz Thomas

    2006-04-01

    Full Text Available Abstract The Council for Secular Humanism identifies Secular Humanism as a "way of thinking and living" committed to rejecting authoritarian beliefs and embracing "individual freedom and responsibility ... and cooperation." The paradigmatic practices of psychiatry are civil commitment and insanity defense, that is, depriving innocent persons of liberty and excusing guilty persons of their crimes: the consequences of both are confinement in institutions ostensibly devoted to the treatment of mental diseases. Black's Law Dictionary states: "Every confinement of the person is an 'imprisonment,' whether it be in a common prison, or in private house, or in the stocks, or even by forcibly detaining one in the public streets." Accordingly, I maintain that Secular Humanism is incompatible with the principles and practices of psychiatry.

  7. Secular humanism and "scientific psychiatry".

    Science.gov (United States)

    Szasz, Thomas

    2006-04-25

    The Council for Secular Humanism identifies Secular Humanism as a "way of thinking and living" committed to rejecting authoritarian beliefs and embracing "individual freedom and responsibility ... and cooperation." The paradigmatic practices of psychiatry are civil commitment and insanity defense, that is, depriving innocent persons of liberty and excusing guilty persons of their crimes: the consequences of both are confinement in institutions ostensibly devoted to the treatment of mental diseases. Black's Law Dictionary states: "Every confinement of the person is an 'imprisonment,' whether it be in a common prison, or in private house, or in the stocks, or even by forcibly detaining one in the public streets." Accordingly, I maintain that Secular Humanism is incompatible with the principles and practices of psychiatry.

  8. THEORY OF SECULAR CHAOS AND MERCURY'S ORBIT

    International Nuclear Information System (INIS)

    Lithwick, Yoram; Wu Yanqin

    2011-01-01

    We study the chaotic orbital evolution of planetary systems, focusing on secular (i.e., orbit-averaged) interactions, which dominate on long timescales. We first focus on the evolution of a test particle that is forced by multiple planets. To linear order in eccentricity and inclination, its orbit precesses with constant frequencies. But nonlinearities modify the frequencies, and can shift them into and out of resonance with either the planets' eigenfrequencies (forming eccentricity or inclination secular resonances), or with linear combinations of those frequencies (forming mixed high-order secular resonances). The overlap of these nonlinear secular resonances drives secular chaos. We calculate the locations and widths of nonlinear secular resonances, display them together on a newly developed map (the 'map of the mean momenta'), and find good agreement between analytical and numerical results. This map also graphically demonstrates how chaos emerges from overlapping secular resonances. We then apply this newfound understanding to Mercury to elucidate the origin of its orbital chaos. We find that since Mercury's two free precession frequencies (in eccentricity and inclination) lie within ∼25% of two other eigenfrequencies in the solar system (those of the Jupiter-dominated eccentricity mode and the Venus-dominated inclination mode), secular resonances involving these four modes overlap and cause Mercury's chaos. We confirm this with N-body integrations by showing that a slew of these resonant angles alternately librate and circulate. Our new analytical understanding allows us to calculate the criterion for Mercury to become chaotic: Jupiter and Venus must have eccentricity and inclination of a few percent. The timescale for Mercury's chaotic diffusion depends sensitively on the forcing. As it is, Mercury appears to be perched on the threshold for chaos, with an instability timescale comparable to the lifetime of the solar system.

  9. Lead evaluation in blood of workers of batteries industries

    International Nuclear Information System (INIS)

    Valbuena P, John J; Duarte, Martha; Marciales Clara

    2001-01-01

    In order to evaluate the occupational risk of exposure to lead of employees working in three small industries that recycle and manufacture acid lead batteries, the lead and zinc protoporphyrine (ZPP) blood content was determined. The determination was also performed on people not exposed in order to establish comparison values. Venous blood was collected in metal free heparinized glass tubes. Lead was analyzed by atomic absorption with graphite furnace and ZPP by fluorescence. According to Colombian legislation, it was found that around 31 % workers in this type of industries are in dangerous and intoxication exposure. It was also found that 91 % of workers exceed the level of 30 mg Pb/dL blood established as standard by the American Conference governmental Industrial Hygienists (ACGIH)

  10. Geomagnetic Core Field Secular Variation Models

    DEFF Research Database (Denmark)

    Gillet, N.; Lesur, V.; Olsen, Nils

    2010-01-01

    highlight the difficulty of resolving the time variability of the high degree secular variation coefficients (i.e. the secular acceleration), arising for instance from the challenge to properly separate sources of internal and of external origin. In addition, the regularisation process may also result...

  11. Fearing Secularism

    DEFF Research Database (Denmark)

    Sheikh, Mona Kanwal

    Secularism and Beyond - Comparative Perspectives: International og interdisciplinær konference, 29. maj-1. juni, 2007Arrangeret af Anders Berg-Sørensen for "Religion i det 21. århundrede" i samarbejde med kolleger fraKøbenhavns Universitet og universiteterne i Wien og Birmingham...

  12. Community blood lead survey with emphasis on preschool children following lead dust pollution in Esperance, Western Australia.

    Science.gov (United States)

    Rossi, Enrico; McLaughlin, Virginia; Joseph, John; Bulsara, Max; Coleman, Kerryn; Douglas, Charles; Robertson, Andrew

    2012-04-01

    To assess the impact of airborne lead dust on blood lead levels in residents of Esperance, a regional Western Australian town, with particular reference to preschool children. Following identification of significant airborne lead contamination, residents were notified that a blood lead clinic was available to all, with testing of preschool children encouraged. About 40% (333 children) of the preschool group and about 20% of the remaining population were tested. The main measures were blood lead levels, prevalence of elevated results and comparisons to other Western Australian surveys. In preschoolers, 2.1% (seven children) had blood lead levels exceeding the current 10 μg/dL level of concern. This was not significantly different to two previous community-based surveys elsewhere in Western Australia. However, at a lower cut-off of 5 μg/dL, the prevalence of elevated lead levels was 24.6%, significantly higher than children tested in a previous Western Australian survey. The prevalence of blood lead levels of 10 μg/dL or greater in adults was 1.3% (26 adults), not significantly different from a previous Western Australian survey. The prevalence of preschool children with blood lead levels exceeding the current level of concern was not significantly increased. However, the increased prevalence of children with lead levels at or above 5 μg/dL demonstrates exposure to lead dust pollution. This episode of lead dust contamination highlights the need for strict adherence to environmental controls and effective monitoring processes to ensure the prevention of future events. © 2012 The Authors. ANZJPH © 2012 Public Health Association of Australia.

  13. Secular Evolution of Spiral Galaxies

    Science.gov (United States)

    2003-01-01

    recombination (z=1000). Furthermore, the BigBang nucleosynthesis model also requires a signi cantamount of non- baryonic dark matter (Primack 1999) ifthe universe...momentum (as well as energy) outward. Associ-ated with this outward angular momentum transport isan expected secular redistribution of disk matter , co...mode, a secular transfer of energy andangular momentum between the disk matter and thedensity wave. The existence of the phase shift betweenthe

  14. Screening children for elevated blood lead - Learnings from the literature

    International Nuclear Information System (INIS)

    Boreland, Frances; Lyle, David

    2008-01-01

    Introduction: Although it is important that children at risk of developing elevated blood lead receive regular screening, attendance at screening programs is variable. A literature review was undertaken to better understand the factors that affect carers' decisions about whether or not to take their children for blood lead screening. Method: Electronic databases (Medline, EMBASE, CINAHL, Psychinfo) were searched to identify relevant publications, supported by reviewing reference lists of identified articles and searching with internet-based search engines. Results: Thirty-four published studies dealing with blood lead screening rates were identified, of which only seven papers focused specifically on parent's attitudes to blood lead screening. The barriers to and enablers of screening for elevated blood lead levels appear to be similar to those identified for other screening programs. Discussion: It is recommended that attendance at screening be routinely monitored, and that where participation is suboptimal further research be undertaken, in close co-operation with affected communities or sub-groups, to determine how best to encourage screening and to protect children from lead. It is important to minimize stigma and to ensure, as far as possible, that practical barriers such as lack of transport do not restrict access to screening programs

  15. Distribution of blood lead levels in schoolchildren in selected cape ...

    African Journals Online (AJOL)

    Objective. To determine blood lead levels among children attending schools in selected Cape Peninsula suburbs, and to assess the impact of a reduction in the lead content of petrol. Design. A cross-sectional analytical study of children's blood lead levels and associated risk factors. Setting. Selected inner city, suburban, ...

  16. The Relation Between Blood Lead Levels and Osteoporosis in Turkish Women

    Directory of Open Access Journals (Sweden)

    Nurver Turfaner Ertürk

    2004-03-01

    Full Text Available Lead is a toxic heavy element which is to 90% deposited in bone until the 6th decade and is given to the blood with pregnancy, lactation and physiologic osteoporosis. When it is over certain amounts it may cause osteoporosis and an increase in cardiac events and cancer. In order to evaluate the effect of menopause and osteoporosis on blood lead 20 post-menopausal osteoporotic, 19 non-osteoporotic and 21 pre-menopausal women were selected and their blood levels were measured. In post-menopausal women, its relation with bone mineral density was also investigated. There was no difference between osteoporotic and non-osteoporotic women and pre and postmenopausal women in terms of blood lead (Pb. There was no relation between age and Pb levels but in non-osteoporotic postmenopausal women there was a negative correlation between Pb levels and duration of menopause. There was no relation between bone mineral density and blood lead whereas blood lead and environmental pollution displayed a meaningful correlation.

  17. Secular humanism and "scientific psychiatry"

    OpenAIRE

    Szasz, Thomas

    2006-01-01

    Abstract The Council for Secular Humanism identifies Secular Humanism as a "way of thinking and living" committed to rejecting authoritarian beliefs and embracing "individual freedom and responsibility ... and cooperation." The paradigmatic practices of psychiatry are civil commitment and insanity defense, that is, depriving innocent persons of liberty and excusing guilty persons of their crimes: the consequences of both are confinement in institutions ostensibly devoted to the treatment of m...

  18. Feminist Practice and Solidarity in Secular Societies : Case Studies on Feminists Crossing Religious–Secular Divides in Politics and Practice in Antwerp, Belgium

    NARCIS (Netherlands)

    van den Brandt, H.P.

    2015-01-01

    In west European countries, public debates on migration, integration, and diversity are informed by particular understandings of secularism and the secular society. In our increasingly diverse societies, so the story goes, it is needed to implement a certain type of secularism and/or support

  19. Secular schools in Zaragoza (1885-1917

    Directory of Open Access Journals (Sweden)

    Alfonso HEREDIA MANRIQUE

    2016-07-01

    Full Text Available This research has a very specific goal that is to know how many and which were secular schools that took place in Zaragoza city, in the period that goes from the first established at the end of the 19th century until the dictatorship of Miguel Primo de Rivera in 1923. Secular schools identified are described by the educational aspects most relevant to that appear in the scarce and scattered remains of them information, and mainly related to the urban location, organization and didactics, teachers and students. All these aspects allow us to glimpse something of how trying to implement his project of secular, rational, scientific education.

  20. Blood lead level and correlation with pregnancy-associated anaemia

    Directory of Open Access Journals (Sweden)

    Jehan Hamadneh

    2018-04-01

    Full Text Available Background The most common reason that leads to anaemia is related to the reduction in certain trace elements such as Fe. However, it has been found that an elevation in some other heavy metals such as Pb could also lead to anaemia. Aims This research aims to assess the Correlation between Pb blood levels and Fe, Haemoglobin levels during pregnancy among Jordanian women. Methods A cross-sectional study was conducted in the Northern area of Jordan. Venous blood samples collected from 167 pregnant women for the determination of haemoglobin (Hb, Fe and Pb levels of which 17 in the first trimester, 19 in second trimesters, 131 in third trimesters. Women were classified into two groups, the first group included cases with blood Pb Levels ≥10µg/dL (high blood Pb level group, n=118 and the second with blood Lead levels less than 10µg/dL (low blood Lead level group, n=49. Results About 71.4 per cent of women had anaemia (n=120; Hb>10.5g/dl and 70.7 per cent of women had a high blood Pb level of ≥10µg/dL. Pb blood levels ranged from 6.45 to 28.0μg/dL. The mean (SD of blood Pb level was 12.1 (4.1 µg/dL. The mean haemoglobin and Fe levels did not differ significantly between women with low and high levels of Pb. Blood Pb levels were not significantly correlated with haemoglobin levels (r=-0.025; P=0.747 nor with iron levels (r=0.099; P=0.241. After adjusting for important variables, Pb was not significantly associated with haemoglobin (P=0.223 and with iron (P=0.116. Conclusion The level of Pb in the blood of pregnant women has no any association with haemoglobin and Fe levels during pregnancy.

  1. Feeding secularism

    DEFF Research Database (Denmark)

    Fischer, Johan

    2005-01-01

    life. He shows how Islamic organizations in Britain claim authority through halal in the interfaces of expanding markets, secularism, and the rights and demands of a growing group of Muslim consumers. These claims emerge in a society where powerful political discourses identify the veiling of Muslim...

  2. Investigation and Evaluation of Children’s Blood Lead Levels around a Lead Battery Factory and Influencing Factors

    Directory of Open Access Journals (Sweden)

    Feng Zhang

    2016-05-01

    Full Text Available Lead pollution incidents have occurred frequently in mainland China, which has caused many lead poisoning incidents. This paper took a battery recycling factory as the subject, and focused on measuring the blood lead levels of environmental samples and all the children living around the factory, and analyzed the relationship between them. We collected blood samples from the surrounding residential area, as well as soil, water, vegetables. The atomic absorption method was applied to measure the lead content in these samples. The basic information of the generation procedure, operation type, habit and personal protect equipment was collected by an occupational hygiene investigation. Blood lead levels in 43.12% of the subjects exceeded 100 μg/L. The 50th and the 95th percentiles were 89 μg/L and 232 μg/L for blood lead levels in children, respectively, and the geometric mean was 94 μg/L. Children were stratified into groups by age, gender, parents’ occupation, distance and direction from the recycling plant. The difference of blood lead levels between groups was significant (p < 0.05. Four risk factors for elevated blood lead levels were found by logistic regression analysis, including younger age, male, shorter distance from the recycling plant, and parents with at least one working in the recycling plant. The rate of excess lead concentration in water was 6.25%, 6.06% in soil and 44.44% in leaf vegetables, which were all higher than the Chinese environment standards. The shorter the distance to the factory, the higher the value of BLL and lead levels in vegetable and environment samples. The lead level in the environmental samples was higher downwind of the recycling plant.

  3. Screening children for elevated blood lead - Learnings from the literature

    Energy Technology Data Exchange (ETDEWEB)

    Boreland, Frances [Broken Hill Centre for Remote Health Research, Broken Hill University Department of Rural Health, University of Sydney, Corrindah Court, PO Box 457, Broken Hill, NSW 2880 (Australia)], E-mail: fboreland@gwahs.health.nsw.gov.au; Lyle, David [Broken Hill Centre for Remote Health Research, Broken Hill University Department of Rural Health, University of Sydney, Corrindah Court, PO Box 457, Broken Hill, NSW 2880 (Australia)], E-mail: dlyle@gwahs.health.nsw.gov.au

    2008-02-01

    Introduction: Although it is important that children at risk of developing elevated blood lead receive regular screening, attendance at screening programs is variable. A literature review was undertaken to better understand the factors that affect carers' decisions about whether or not to take their children for blood lead screening. Method: Electronic databases (Medline, EMBASE, CINAHL, Psychinfo) were searched to identify relevant publications, supported by reviewing reference lists of identified articles and searching with internet-based search engines. Results: Thirty-four published studies dealing with blood lead screening rates were identified, of which only seven papers focused specifically on parent's attitudes to blood lead screening. The barriers to and enablers of screening for elevated blood lead levels appear to be similar to those identified for other screening programs. Discussion: It is recommended that attendance at screening be routinely monitored, and that where participation is suboptimal further research be undertaken, in close co-operation with affected communities or sub-groups, to determine how best to encourage screening and to protect children from lead. It is important to minimize stigma and to ensure, as far as possible, that practical barriers such as lack of transport do not restrict access to screening programs.

  4. Elevated blood lead levels from exposure via a radiator workshop.

    Science.gov (United States)

    Treble, R G; Thompson, T S; Morton, D N

    1998-04-01

    Elevated lead levels were discovered in blood samples collected from family members where both the father and the mother worked in a radiator repair workshop. The father and mother were found to have blood lead levels of 2.0 and 0.5 mumol/L (41.7 and 10.4 micrograms/dL), respectively. The father's blood lead level was just below the Canadian occupational health and safety intervention level (2.5 mumol/L or 52.1 micrograms/dL). The two children had blood lead levels of 1.0 and 0.8 mumol/L (20.8 and 16.7 micrograms/dL), both of which are in excess of the recommended guideline for intervention in the case of children (0.5 mumol/L or 10.4 micrograms/dL). The exposure of the two children was possibly due to a combination of pathways including exposure at the workshop itself during visits and also the transportation of lead-containing dust to the home environment.

  5. How High Blood Pressure Can Lead to Stroke

    Science.gov (United States)

    ... Disease Venous Thromboembolism Aortic Aneurysm More How High Blood Pressure Can Lead to Stroke Updated:Jan 29,2018 ... This content was last reviewed October 2016. High Blood Pressure • Home • Get the Facts About HBP • Know Your ...

  6. Unsafe Gods: Security, Secularism and Schooling

    Science.gov (United States)

    Davies, Lynn

    2014-01-01

    This book makes the compelling argument that religion can be complicit in conflict and that a new secularism is vital to foster security. Using insights from complexity science, it shows how dynamic secularism can be used to accommodate diverse faiths and beliefs within worldly politics. Exploration of the interplay of religion and education in…

  7. Occurrence of lead-related symptoms below the current occupational safety and health act allowable blood lead levels.

    Science.gov (United States)

    Rosenman, Kenneth D; Sims, Amy; Luo, Zhehui; Gardiner, Joseph

    2003-05-01

    To determine the occurrence of symptoms of lead toxicity at levels below the current allowable Occupational Safety and Health Act blood lead level of 50 micrograms/dL, standardized telephone interviews were conducted of individuals reported to a statewide laboratory-based surveillance system. Four hundred and ninety-seven, or 75%, of the eligible participants were interviewed. Gastrointestinal, musculoskeletal, and nervous system symptoms increased with increasing blood lead levels. Nervous, gastrointestinal, and musculoskeletal symptoms all began to be increased in individuals with blood leads between 30-39 micrograms/dL and possibly at levels as low as 25-30 micrograms/dL for nervous system symptoms. The results of this study of increased symptoms are consistent with and provide added weight to previous results showing subclinical changes in the neurologic and renal systems and sperm counts at blood lead levels currently allowed by the Occupational Safety and Health Act.

  8. Explaining Global Secularity: Existential Security or Education?

    Directory of Open Access Journals (Sweden)

    Claude M. J. Braun

    2012-11-01

    Full Text Available At the time of data analysis for this report there were 193 countries in the world. Various institutions – the United Nations, the World Health Organization, the CIA, the World Values Survey, Gallup, and many others – have performed sophisticated statistical analyses on cross-national data. The present investigation demonstrates that valid and reliable data concerning religiosity and secularity exist for most countries and that these data are comparable. Cross-national data relating to social, political, economic and cultural aspects of life were tested for correlation with religiosity/secularity. In contrast to the most widely accepted general account of secularity, the Existential Security Framework (ESF; Norris & Inglehart, 2004, secularity was not most highly related to material security, though these were highly related. Rather, secularity was most strongly related to the degree of formal education attained. Material security explained no significant variance beyond education. Thus, religion’s primary function in the world today is being replaced, not so much by the pseudo-materialistic supplication for better living conditions as posited by the ESF, but by contemporary education – extensive knowledge of contemporary cultures, philosophy, modes of thought or processes of reasoning.

  9. BLOOD LEAD CONCENTRATION AND DELAYED PUBERTY IN GIRLS

    Science.gov (United States)

    Background Environmental lead exposure has been linked to alterations in growth and endocrine function. It is not known whether such exposure affects pubertal development.Methods We analyzed the relations between blood lead concentration and pubertal...

  10. Constitutionalizing secularism, alternative secularisms or liberal-democratic constitutionalism?
    A critical reading of some Turkish, ECtHR and Indian Supreme Court cases on ‘secularism’

    Directory of Open Access Journals (Sweden)

    Veit Bader

    2010-11-01

    Full Text Available In recent debates on the constitutional status of 'secularism' we can discern three positions. The first tries to overcome the absence of 'secularism' in most liberal-democratic constitutions by developing a more robust theory of constitutional secularism. The second develops theories of 'alternative secularisms'. The third, defended in this article, argues that we should drop secularism as a 'cacophonous' concept from our constitutional and legal language and replace it by liberal-democratic constitutionalism. I develop an analytical taxonomy of twelve different meanings of 'secularism' based on a comparative study of Turkish and Indian Supreme Court cases on secularism, and demonstrate that they are incompatible with each other and with the hard core of liberal-democratic constitutions. Next, I criticize the respective rulings in the Turkish and Indian context. Particularly in 'militant democracies', the appeal to a principle of 'secularism' turns out to be inimical to the liberal and to the democratic 'constitutional essentials'. I end with some normative recommendations on the role of constitutional review and judicial activism.

  11. Moderate Secularism, Difference Sensitivity and Contextualism

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2009-01-01

    The article is a rejoinder to Tariq Modood's reply (Politics, Vol. 29, No. 1, 2009) to my article 'Moderate Secularism and Multicultural Equality' (Politics, Vol 28, No. 3, 2008).......The article is a rejoinder to Tariq Modood's reply (Politics, Vol. 29, No. 1, 2009) to my article 'Moderate Secularism and Multicultural Equality' (Politics, Vol 28, No. 3, 2008)....

  12. Concept and Indications of Secular State

    Directory of Open Access Journals (Sweden)

    Philina N. V.

    2014-10-01

    Full Text Available The article deals with the elaborate analysis of the concept and indications of a secular state. The paper has the interdisciplinary character and it is written on the verge of constitutional law, theory of state administration, philosophy, political science. The comparative analysis between the constitutional indicators of a secular state and democracy realia has been conducted

  13. Determination of Lead in Blood by Atomic Absorption Spectrophotometry1

    Science.gov (United States)

    Selander, Stig; Cramér, Kim

    1968-01-01

    Lead in blood was determined by atomic absorption spectrophotometry, using a wet ashing procedure and a procedure in which the proteins were precipitated with trichloroacetic acid. In both methods the lead was extracted into isobutylmethylketone before measurement, using ammonium pyrrolidine dithiocarbamate as chelator. The simpler precipitation procedure was shown to give results identical with those obtained with the ashing technique. In addition, blood specimens were examined by the precipitation method and by spectral analysis, which method includes wet ashing of the samples, with good agreement. All analyses were done on blood samples from `normal' persons or from lead-exposed workers, and no additions of inorganic lead were made. The relatively simple protein precipitation technique gave accurate results and is suitable for the large-scale control of lead-exposed workers. PMID:5663425

  14. The equations of motion of a secularly precessing elliptical orbit

    Science.gov (United States)

    Casotto, S.; Bardella, M.

    2013-01-01

    The equations of motion of a secularly precessing ellipse are developed using time as the independent variable. The equations are useful when integrating numerically the perturbations about a reference trajectory which is subject to secular perturbations in the node, the argument of pericentre and the mean motion. Usually this is done in connection with Encke's method to ensure minimal rectification frequency. Similar equations are already available in the literature, but they are either given based on the true anomaly as the independent variable or in mixed mode with respect to time through the use of a supporting equation to track the anomaly. The equations developed here form a complete and independent set of six equations in time. Reformulations both of Escobal's and Kyner and Bennett's equations are also provided which lead to a more concise form.

  15. Comparison of blood lead levels of mothers and cord blood in intrauterine growth retarded neonates and normal term neonates

    International Nuclear Information System (INIS)

    Iranpour, R.; Besharati, Amir A.; Nasseri, F.; Hashemipour, M.; Kelishadi, R.; Balali-Mood, M.

    2007-01-01

    Objective was to compare the blood lead levels of mothers and cord blood in intrauterine growth retarded (IUGR) neonates and normal term neonates. From April 2005, we carried out a cross-sectional, prospective study in Isfahan University of Medical Sciences, Isfahan, Iran. Blood lead levels were measured in the umbilical cord and maternal venous blood samples in the 32 mother-infant pairs with IUGR full term neonates and 34 mother-infant pairs with normal full term neonates. Blood-lead levels were analyzed by atomic absorption spectrometry. The mean lead concentration in neonates of IUGR and normal groups was not significantly different (107.47+- 16.75 versus 113.08+-19.08 ug/L, p=0.2). The mean lead concentration in mothers of IUGR group was lower than normal groups, but this difference was not significant (124.56+-19.71 versus 135.26+-26.91 ug/L, p=0.07). Maternal lead levels were strongly related with related with cord blood in both IUGR and normal groups (r=0.8, p 100ug/L by the centers for disease control; however, this was not statistically different between the groups. Our results indicate that the mean lead level was not higher in IUGR neonates, and the whole blood lead was not related to the birth weight. In addition, maternal and cord blood lead levels were strongly correlated, and there were remarkable lead burdens on both the mothers and their neonates in this industrial area. (author)

  16. Blood lead: Its effect on trace element levels and iron structure in hemoglobin

    International Nuclear Information System (INIS)

    Jin, C.; Li, Y.; Li, Y.L.; Zou, Y.; Zhang, G.L.; Normura, M.; Zhu, G.Y.

    2008-01-01

    Lead is a ubiquitous environmental pollutant that induce a broad range of physiological and biochemical dysfunctions. The purpose of this study was to investigate its effects on trace elements and the iron structure in hemoglobin. Blood samples were collected from rats that had been exposed to lead. The concentration of trace elements in whole blood and blood plasma was determined by ICP-MS and the results indicate that lead exists mainly in the red blood cells and only about 1-3% in the blood plasma. Following lead exposure, the concentrations of zinc and iron in blood decrease, as does the hemoglobin level. This indicates that the heme biosynthetic pathway is inhibited by lead toxicity and that lead poisoning-associated anemia occurs. The selenium concentration also decreases after lead exposure, which may lead to an increased rate of free radical production. The effect of lead in the blood on iron structure in hemoglobin was determined by EXAFS. After lead exposure, the Fe-O bond length increases by about 0.07 A and the Fe-Np bond length slightly increases, but the Fe-N ε bond length remains unchanged. This indicates that the blood content of Hb increases, but that the content of HbO 2 decreases

  17. Blood lead levels among rural Thai children exposed to lead-acid batteries from solar energy conversion systems.

    Science.gov (United States)

    Swaddiwudhipong, Witaya; Tontiwattanasap, Worawit; Khunyotying, Wanlee; Sanreun, Cherd

    2013-11-01

    We evaluate blood lead levels among Thai children to determine if exposure to lead-acid batteries is associated with elevated blood lead levels (EBLL). We screened 254 children aged 1-14 years old from 2 rural Thai villages for blood lead levels. We also screened 18 of 92 houses in these 2 villages for the presence of environmental lead. The overall prevalence of EBLL (> or = 10 microg/dl) was 43.3% and the mean lead level among study subjects was 9.8 +/- 5.1 microg/dl. The blood lead levels significantly decreased with increasing age. Fifty point eight percent of children who lived in a house with vented lead-acid batteries had EBLL while 23.3% of children who lived in a house without vented lead-acid batteries had EBLL. Multiple logistic regression analysis revealed a significant positive association between the presence of vented lead-acid batteries and EBLL, after adjusting for other variables. Forty-two point nine percent of house floor dust samples collected near the batteries had elevated lead levels, 7.1% of house floor dust samples collected from other areas in the house had elevated lead levels and 0% of the house floor dust samples collected in houses without vented lead-acid batteries had elevated lead levels. In the sampled houses with vented lead-acid batteries, lead contamination was found in the drinking-water kept in household containers, but not in the tap water or other village sources of water. Improper care and placement of vented lead-acid batteries can result in lead contamination in the home environment causing EBLL in exposed children.

  18. Modeling the secular evolution of migrating planet pairs

    Science.gov (United States)

    Michtchenko, T. A.; Rodríguez, A.

    2011-10-01

    The secular regime of motion of multi-planetary systems is universal; in contrast with the 'accidental' resonant motion, characteristic only for specific configurations of the planets, secular motion is present everywhere in phase space, even inside the resonant region. The secular behavior of a pair of planets evolving under dissipative forces is the principal subject of this study, particularly, the case when the dissipative forces affect the planetary semi-major axes and the planets move inward/outward the central star, the process known as planet migration. Based on the fundamental concepts of conservative and dissipative dynamics of the three-body problem, we develop a qualitative model of the secular evolution of the migrating planetary pair. Our approach is based on analysis of the energy and the orbital angular momentum exchange between the two-planet system and an external medium; thus no specific kind of dissipative forces is invoked. We show that, under assumption that dissipation is weak and slow, the evolutionary routes of the migrating planets are traced by the Mode I and Mode II stationary solutions of the conservative secular problem. The ultimate convergence and the evolution of the system along one of these secular modes of motion is determined uniquely by the condition that the dissipation rate is sufficiently smaller than the proper secular frequency of the system. We show that it is possible to reassemble the starting configurations and migration history of the systems on the basis of their final states and consequently to constrain the parameters of the physical processes involved.

  19. Experimental lead intoxication in dogs: a comparison of blood lead and urinary delta-aminolevulinic acid following intoxication and chelation therapy.

    Science.gov (United States)

    Green, R A; Selby, L A; Zumwalt, R W

    1978-01-01

    Intravenous lead administration to dogs produced an acute syndrome of lead intoxication charcterized by depression, vomiting, anorexia and weight loss. The effect of chelation therapy with calcium disodium ethylene diamine tetraacetate, penicillamine or both was determined by serially monitoring changes in blood lead and urine delta-aminolevulinic acid. Following therapy, blood lead values were significantly lower in chelated dogs than non-treated lead exposed dogs on days 7 and 10. Urine delta-aminolevulinic acid at day 7 was significantly higher in untreated lead exposed dogs than in other groups. There was no significant difference in blood lead or urine delta-aminolevulinic acid between lead intoxicated dogs which underwent the indicated chelation therapy protocols. There was, however, a trend for higher urinary delta-aminolevulinic acid excretion in those intoxicated dogs undergoing calcium disodium ethylene diamine tetraacetate therapy as opposed to those undergoing penicilamine therapy. There was no significant correlation between blood lead and urinary delta-aminolevulinic acid previous to lead exposure. However, after lead exposure significant correlation was present at days 4, 7, 10 and 14. Certain lead exposed dogs following chelation therapy were noted to have normal blood lead levels but elevated urinary delta-aminolevulinic acid suggesting that blood lead does not always correlate with metabolic effects of lead in the body. Urinary delta-aminolevulinic acid was therefore recommended as an additional laboratory parameter which improved assessment of lead exposure in dogs, particularly in determining adequacy of chelation therapy. PMID:667707

  20. Secular trends of blood isolates in patients from a rural area population hospitalized in a tertiary center in a small city in Greece

    Directory of Open Access Journals (Sweden)

    Holevas Pierros V

    2006-05-01

    Full Text Available Abstract Background Most of the studies evaluating the secular trends of blood isolates come from tertiary hospitals in urban areas. We sought to study the trends of the antimicrobial resistance of blood isolates in patients from a rural population hospitalized in a tertiary hospital in a small city in Greece. Methods We retrospectively collected and analysed data for the first positive blood culture obtained for each admission for each patient hospitalized in General Hospital of Tripolis, Tripolis, Peloponnesus, Greece during a 5 year period (16/05/2000 – 15/05/2005. Results Sixty-seven thousand and seventy patients were hospitalized during the study period from whom 3,206 blood cultures were obtained. A higher increase of the number of obtained blood cultures than the number of admissions was noted during the study period (p Escherichia coli (29%, and Staphylococcus aureus (18.2% were the most commonly isolated pathogens. Among the Staphylococcus aureus isolates, the proportion of methicillin-resistant Staphylococcus aureus (MRSA was 17.2% (5/29. The proportion of Escherichia coli resistant to trimethoprim and sulfamethoxazole, ampicillin and cefuroxime was 29.6% (32/108, 25.0% (27/108, and 8.3% (9/108 respectively. Imipenem-resistance was noted in 3.4% (1/29 of Pseudomonas aeruginosa isolates. There were only 6 (1.6% Acinetobacter baummanii blood isolates during the study period. Conclusion The antimicrobial resistance of isolates from patients receiving care at the studied tertiary hospital in a small city in Greece is considerably less compared to that noted in tertiary hospitals in larger cities of the country.

  1. Prenatal exposure to lead in Spain: Cord blood levels and associated factors

    Energy Technology Data Exchange (ETDEWEB)

    Llop, Sabrina, E-mail: llop_sab@gva.es [Centre of Public Health Research (CSISP), Av Catalunya 21, 46020, Valencia (Spain); Carlos III Health Institute (ISCIII), 20220 Majadahonda, Madrid (Spain); CIBER de Epidemiologia y Salud Publica (CIBERESP), Doctor Aiguader 88, 8003 Barcelona (Spain); Aguinagalde, Xabier [Public Health Laboratory of Alava, Direccion de Salud Publica, Gobierno Vasco, Santiago 11, 01002, Vitoria-Gasteiz, Basque Country (Spain); Vioque, Jesus [CIBER de Epidemiologia y Salud Publica (CIBERESP), Doctor Aiguader 88, 8003 Barcelona (Spain); Universidad Miguel Hernandez, Av de Alicante KM 87, 03550, Sant Joan d' Alacant (Spain); Ibarluzea, Jesus [CIBER de Epidemiologia y Salud Publica (CIBERESP), Doctor Aiguader 88, 8003 Barcelona (Spain); Departamento de Sanidad Gobierno Vasco, Subdireccion de Salud Publica de Gipuzkoa, Avenida de Navarra 4, 20013 San Sebastian (Spain); Biodonostia, Instituto de Investigacion Biomedica, San Sebastian (Spain); Guxens, Monica [CIBER de Epidemiologia y Salud Publica (CIBERESP), Doctor Aiguader 88, 8003 Barcelona (Spain); Centre for Research of Environmental Epidemiology (CREAL), Doctor Aiguader 88, 8003 Barcelona (Spain); Municipal Institute of Medical Research (IMIM-Hospital del Mar), Doctor Aiguader 88, 8003 Barcelona (Spain); Casas, Maribel [Centre for Research of Environmental Epidemiology (CREAL), Doctor Aiguader 88, 8003 Barcelona (Spain); Municipal Institute of Medical Research (IMIM-Hospital del Mar), Doctor Aiguader 88, 8003 Barcelona (Spain); Murcia, Mario [Centre of Public Health Research (CSISP), Av Catalunya 21, 46020, Valencia (Spain); CIBER de Epidemiologia y Salud Publica (CIBERESP), Doctor Aiguader 88, 8003 Barcelona (Spain); Ruiz, Maria [Centre for Research of Environmental Epidemiology (CREAL), Doctor Aiguader 88, 8003 Barcelona (Spain); Municipal Institute of Medical Research (IMIM-Hospital del Mar), Doctor Aiguader 88, 8003 Barcelona (Spain); and others

    2011-05-01

    Introduction and Objective: Lead is a known neurotoxic. Fetuses and infants are very vulnerable to lead exposure, since their blood-brain barrier is not completely formed. Hence, there is an importance for monitoring of blood lead levels prenatally and during early infancy. The aim of this study is to evaluate the prenatal exposure to lead and its association with maternal factors in four population based mother-child cohorts in Spain. The present research was carried out within the framework of the INMA project INfancia y Medio Ambiente (Environment and Childhood). Methods: A total of 1462 pregnant women were recruited between 2004 and 2008. Lead was analyzed in a sample of cord blood by thermal decomposition, amalgation, and Atomic Absorption Spectrometry. Maternal sociodemographic, lifestyle and dietary factors were obtained by questionnaires during pregnancy. A multivariate logistic regression model was constructed. The dependent variable was a dichotomous lead level variable (detected vs no detected, i.e. {>=} vs < 2 {mu}g/dL). Results: A low percentage of cord blood samples with lead levels {>=} 2 {mu}g/dL were found (5.9%). Geometric mean and maximum were 1.06 {mu}g/dL and 19 {mu}g/dL, respectively. Smoking at the beginning of pregnancy, age, social class, weight gain during pregnancy, gravidity, and place of residence were the maternal factors associated with detectable cord blood lead levels. Mother's diet does not appear to be a determining factor of lead exposure. Nevertheless, daily intake of iron and zinc may act as a protective factor against having cord blood lead levels {>=} 2 {mu}g/dL. Conclusion: In the different regions of Spain taking part in this study, lead levels to which newborns are exposed are low. Mobilization of lead from bones may be the main contributor to the cord blood levels. - Research Highlights: {yields} Pb is a ubiquitous environmental pollutant with harmful effects on neurodevelopment. {yields} Cord blood Pb levels in

  2. Prenatal exposure to lead in Spain: Cord blood levels and associated factors

    International Nuclear Information System (INIS)

    Llop, Sabrina; Aguinagalde, Xabier; Vioque, Jesus; Ibarluzea, Jesus; Guxens, Monica; Casas, Maribel; Murcia, Mario; Ruiz, Maria

    2011-01-01

    Introduction and Objective: Lead is a known neurotoxic. Fetuses and infants are very vulnerable to lead exposure, since their blood-brain barrier is not completely formed. Hence, there is an importance for monitoring of blood lead levels prenatally and during early infancy. The aim of this study is to evaluate the prenatal exposure to lead and its association with maternal factors in four population based mother-child cohorts in Spain. The present research was carried out within the framework of the INMA project INfancia y Medio Ambiente (Environment and Childhood). Methods: A total of 1462 pregnant women were recruited between 2004 and 2008. Lead was analyzed in a sample of cord blood by thermal decomposition, amalgation, and Atomic Absorption Spectrometry. Maternal sociodemographic, lifestyle and dietary factors were obtained by questionnaires during pregnancy. A multivariate logistic regression model was constructed. The dependent variable was a dichotomous lead level variable (detected vs no detected, i.e. ≥ vs < 2 μg/dL). Results: A low percentage of cord blood samples with lead levels ≥ 2 μg/dL were found (5.9%). Geometric mean and maximum were 1.06 μg/dL and 19 μg/dL, respectively. Smoking at the beginning of pregnancy, age, social class, weight gain during pregnancy, gravidity, and place of residence were the maternal factors associated with detectable cord blood lead levels. Mother's diet does not appear to be a determining factor of lead exposure. Nevertheless, daily intake of iron and zinc may act as a protective factor against having cord blood lead levels ≥ 2 μg/dL. Conclusion: In the different regions of Spain taking part in this study, lead levels to which newborns are exposed are low. Mobilization of lead from bones may be the main contributor to the cord blood levels. - Research Highlights: → Pb is a ubiquitous environmental pollutant with harmful effects on neurodevelopment. → Cord blood Pb levels in Spanish newborn are low in

  3. Lead levels in the workers blood at the Toluca bus terminal

    International Nuclear Information System (INIS)

    Gomez H, S.P.; Garcia G, G.

    1998-01-01

    The study was carried out in order to detect the levels of lead in blood in exposed workers to the lead in their place of work, in the Toluca bus terminal. The measurement of the levels of lead in blood was carried out in a sample of 31 people of 60 workers for atomic absorption spectrometry. The lead is a general protoplasmic poison that is accumulative and produce great variety of symptoms, the lead could be absorbed inside the body for ingestion, inhalation and through the skin. Organic compounds of the lead as tetraethyl lead, penetrate the cutaneous barrier quickly. From the beginning the personal habits were evaluated, hygienic, nutritious and the environmental conditions by means of a questionnaire. The levels of lead in opposing blood, they were below them you limit permissible for personal exposed, published by the WHO. (Author)

  4. Determining Childhood Blood Lead Level Screening Compliance Among Physicians.

    Science.gov (United States)

    Haboush-Deloye, Amanda; Marquez, Erika R; Gerstenberger, Shawn L

    2017-08-01

    Childhood Lead Poisoning Prevention Programs throughout the U.S. have addressed childhood lead poisoning by implementing primary and secondary prevention efforts. While many programs have helped increase screening rates, in some states children under the age of six still have not been tested for lead. This study aims to identify the barriers to childhood blood lead testing and develop a strategy to increase the number of children tested. Clark County physicians who work with children six and under were surveyed about blood lead level (BLL) testing practices, particularly, adherence to Centers for Disease Control and Prevention (CDC) guidelines, and parental compliance with orders to have their children tested to determine their blood lead levels. In addition, select in-person interviews were conducted with physicians who reported high parental compliance to identify best practices and barriers. Of the 77 physicians that provided data, 48% indicated they did not follow CDC guideline compared to 52% who follow guidelines. 18 of the 30 (or 60%) physicians reported more than 80% of parents complied with doctor recommended BLL testing. Twelve physicians identified cost, lack of insurance, and absence of symptomology as persistent barriers to lead screening. This study identified barriers to childhood lead screening including inadequate parental adherence to physician-ordered screenings and physician non-compliance with screening recommendations are two primary contributors. Addressing these issues could increase screening in children and reduce the risk of lead poisoning.

  5. Secular Evolution in Disk Galaxies

    Science.gov (United States)

    Kormendy, John

    2013-10-01

    bulges because the latter retain a `memory' of their disky origin. That is, they have one or more characteristics of disks: (1) flatter shapes than those of classical bulges, (2) correspondingly large ratios of ordered to random velocities, (3) small velocity dispersions with respect to the Faber-Jackson correlation between velocity dispersion and bulge luminosity, (4) spiral structure or nuclear bars in the `bulge' part of the light profile, (5) nearly exponential brightness profiles and (6) starbursts. So the cleanest examples of pseudobulges are recognisable. However, pseudo and classical bulges can coexist in the same galaxy. I review two important implications of secular evolution: (1) The existence of pseudobulges highlights a problem with our theory of galaxy formation by hierarchical clustering. We cannot explain galaxies that are completely bulgeless. Galaxy mergers are expected to happen often enough so that every giant galaxy should have a classical bulge. But we observe that bulgeless giant galaxies are common in field environments. We now realise that many dense centres of galaxies that we used to think are bulges were not made by mergers; they were grown out of disks. So the challenge gets more difficult. This is the biggest problem faced by our theory of galaxy formation. (2) Pseudobulges are observed to contain supermassive black holes (BHs), but they do not show the well-known, tight correlations between BH mass and the mass and velocity dispersion of the host bulge. This leads to the suggestion that there are two fundamentally different BH feeding processes. Rapid global inward gas transport in galaxy mergers leads to giant BHs that correlate with host ellipticals and classical bulges, whereas local and more stochastic feeding of small BHs in largely bulgeless galaxies evidently involves too little energy feedback to result in BH-host coevolution. It is an important success of the secular evolution picture that morphological differences can be used to

  6. The relationship between environmental lead and blood lead in children : a study in environmental epidemiology

    NARCIS (Netherlands)

    Brunekreef, B.

    1985-01-01

    This study deals with the relationship between environmental lead and blood lead in children.
    Chapter 1 provides a summary of the environmental health aspects of lead. The occurrence of lead in the environment and in man is described; children are discussed as a population at

  7. There is a Sexular Body: Introducing a Material Approach to the Secular

    Directory of Open Access Journals (Sweden)

    Jelle Wiering

    2017-05-01

    Full Text Available This article calls for more ‘bottom-up inquiry’ into the secular, departing from the assumption that it features normative ideologies and practices that dominate current societies. I plea for collecting and analyzing manifestations of the secular, as the secular as an phenomenon in society is surprisingly unexplored. To stimulate such inquiry, I suggest a material approach to the secular, as it will provide researchers with tools to conduct empirical research on the secular in contemporary societies. Inspired by Joan Scott, Charles Hirschkind, and Talal Asad, this article explores the notion of a Dutch ‘sexular’ body: a body which affective-gestural repertoires, limited here to the context of sexuality, people in society (historically associate with the secular. I conclude by arguing that a material approach to the secular will contribute to (1 obtaining a more comprehensive understanding of the secular, including its cultural conceptualizations and manifestations, and (2 clarifying, and hence facing the normativity the secular imposes on the people living in secular societies.

  8. Blood lead levels in children with neurological disorders: a single centre preliminary study.

    Science.gov (United States)

    Mahmoudian, Touran; Modaresi, Mohamadreza; Zarei, Ali; Poursafa, Parinaz; Kelishadi, Roya

    2009-11-01

    Lead poisoning is a potentially devastating problem among young children. Chronic low level lead exposure can lead to learning disabilities and behavior changes such as colic, insomnia, hyperactivity, impaired growth, hearing loss and upper extremity weakness. The purpose of this cross sectional study was to determine the blood lead level in children with neurological disorders in comparison with healthy controls. Blood lead concentrations were measured by flame atomic absorption spectrometry in 100 children aged 1-10 years and suffering from various neurological disorders. One hundred age and sex-matched healthy children served as controls. The mean blood lead concentration was higher in children with neurological disorders than in controls (113.2 + or - 47.5 microg/L vs 84.7 + or - 38.0 microg/L; pchildren with neurological disorders and 19% of controls were found to have increased blood lead levels, i.e.>100 microg/L. An increase in blood lead level in children might be related to neurological disorders. The measurement of blood lead level might be included in diagnostic eveluation of children with neurological disorders.

  9. A Pilot Study of Children's Blood Lead Levels in Mount Isa, Queensland.

    Science.gov (United States)

    Green, Donna; Sullivan, Marianne; Cooper, Nathan; Dean, Annika; Marquez, Cielo

    2017-12-13

    Mount Isa, Queensland, is one of three Australian cities with significant lead emissions due to nonferrous mining and smelting. Unlike the two other cities with lead mines or smelters, Mount Isa currently has no system of annual, systematic, community-wide blood lead level testing; and testing rates among Indigenous children are low. In previous screenings, this group of children has been shown to have higher average blood lead levels than non-Indigenous children. The first aim of this study was to assess whether parents and children would participate in less invasive, rapid point-of-care capillary testing. The second aim was to measure blood lead levels among a range of children that roughly reflected the percentage of the Indigenous/non-Indigenous population. This pilot study is based on a convenience sample of children between the ages of 12 and 83 months who were recruited to participate by staff at a Children and Family Centre. Over three half-days, 30 children were tested using capillary blood samples and the LeadCare II Point-of-Care testing system. Rapid point-of-care capillary testing was well tolerated by the children. Of 30 children tested, 40% ( n = 12) had blood lead levels ≥5 µg/dL and 10% had levels ≥10 µg/dL. The highest blood lead level measured was 17.3 µg/dL. The percentage of children with blood lead levels ≥5 µg/dL was higher among Indigenous children compared to non-Indigenous (64.2% compared to 18.8%) as was the geometric mean level (6.5 (95% CI, 4.7, 9.2) versus 2.4 (95% CI, 1.8, 3.1)), a statistically significant difference. Though based on a small convenience sample, this study identified 12 children (40%) of the sample with blood lead levels ≥5 µg/dL. Due to historical and ongoing heavy metal emissions from mining and smelting in Mount Isa, we recommend a multi-component program of universal blood lead level testing, culturally appropriate follow-up and intervention for children who are identified with blood lead levels ≥5

  10. Prenatal exposure to lead in Spain: cord blood levels and associated factors.

    Science.gov (United States)

    Llop, Sabrina; Aguinagalde, Xabier; Vioque, Jesus; Ibarluzea, Jesús; Guxens, Mònica; Casas, Maribel; Murcia, Mario; Ruiz, María; Amurrio, Ascensión; Rebagliato, Marisa; Marina, Loreto Santa; Fernandez-Somoano, Ana; Tardon, Adonina; Ballester, Ferran

    2011-05-01

    Lead is a known neurotoxic. Fetuses and infants are very vulnerable to lead exposure, since their blood-brain barrier is not completely formed. Hence, there is an importance for monitoring of blood lead levels prenatally and during early infancy. The aim of this study is to evaluate the prenatal exposure to lead and its association with maternal factors in four population based mother-child cohorts in Spain. The present research was carried out within the framework of the INMA project INfancia y Medio Ambiente (Environment and Childhood). A total of 1462 pregnant women were recruited between 2004 and 2008. Lead was analyzed in a sample of cord blood by thermal decomposition, amalgation, and Atomic Absorption Spectrometry. Maternal sociodemographic, lifestyle and dietary factors were obtained by questionnaires during pregnancy. A multivariate logistic regression model was constructed. The dependent variable was a dichotomous lead level variable (detected vs no detected, i.e. ≥ vs < 2μg/dL). A low percentage of cord blood samples with lead levels ≥ 2μg/dL were found (5.9%). Geometric mean and maximum were 1.06μg/dL and 19μg/dL, respectively. Smoking at the beginning of pregnancy, age, social class, weight gain during pregnancy, gravidity, and place of residence were the maternal factors associated with detectable cord blood lead levels. Mother's diet does not appear to be a determining factor of lead exposure. Nevertheless, daily intake of iron and zinc may act as a protective factor against having cord blood lead levels ≥ 2μg/dL. In the different regions of Spain taking part in this study, lead levels to which newborns are exposed are low. Mobilization of lead from bones may be the main contributor to the cord blood levels. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. Evaluation of blood zinc, calcium and blood lead levels among children aged 1-36 months.

    Science.gov (United States)

    Ji, Xiaojun; He, Hong; Ren, Lisheng; Liu, Ji; Han, Chunhua

    2014-09-01

    Early childhood lead exposure is associated with numerous adverse health effects. Biomonitoring among susceptible populations, such as children, has not been previously conducted. The aim of the study is to evaluate the blood lead (Pb) and total blood calcium (Ca) levels; blood zinc (Zn) levels. A cross-sectional study was designed to collect healthy children age 1- 36 months (Mean ± SD: 1.5 ± 0.6 age, 60% boys) in the study from January 2010 to September 2011. The overall mean blood Pb levels were 42.18 ± 12.13 μg/L, the overall mean blood Zn and total blood Ca concentrations were 62.18 ± 12.33 μmol/L and 1.78 ± 0.13 mmol/L, respectively. The prevalence of elevated blood Pb levels in all children was 1.3%. A significant difference was found between female and male subjects for the blood Pb and Zn. After controlling for gender and age, there was a weak positive correlation between total blood Ca and Zn level. The blood Pb levels had a significant negative correlation with total blood Ca level after adjusting for age and gender, and these findings suggest that Pb had effect on positive blood Zn and total blood Ca levels; parents should pay more attention to the nutrition of girls. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  12. Varieties of Secularism in Asia

    DEFF Research Database (Denmark)

    of the North Atlantic rim. This anthology seeks to begin that task. It does so by suggesting that the kind of secularity described by Taylor is only one amongst others. By attending to the shifting relationship between proper religion and ‘bad faiths’; between politically valorised and embarrassing spiritual...... phenomena; between the new visibilities and silences of magic, ancestors, and religion in democratic politics, this book seeks to outline the particular formations of secularism that have become possible in Asia from China to Indonesia and from Bahrain to Timor-Leste....

  13. Unsaturated Fatty Acids Supplementation Reduces Blood Lead Level in Rats

    Science.gov (United States)

    Skoczyńska, Anna; Wojakowska, Anna; Nowacki, Dorian; Bobak, Łukasz; Turczyn, Barbara; Smyk, Beata; Szuba, Andrzej; Trziszka, Tadeusz

    2015-01-01

    Some dietary factors could inhibit lead toxicity. The aim of this study was to evaluate the effect of dietary compounds rich in unsaturated fatty acids (FA) on blood lead level, lipid metabolism, and vascular reactivity in rats. Serum metallothionein and organs' lead level were evaluated with the aim of assessing the possible mechanism of unsaturated FA impact on blood lead level. For three months, male Wistar rats that were receiving drinking water with (100 ppm Pb) or without lead acetate were supplemented per os daily with virgin olive oil or linseed oil (0.2 mL/kg b.w.) or egg derived lecithin fraction: “super lecithin” (50 g/kg b.w.). Mesenteric artery was stimulated ex vivo by norepinephrine (NE) administered at six different doses. Lecithin supplementation slightly reduced pressor responses of artery to NE. Lead administered to rats attenuated the beneficial effect of unsaturated FA on lipid metabolism and vascular reactivity to adrenergic stimulation. On the other hand, the super lecithin and linseed oil that were characterized by low omega-6 to omega-3 ratio (about 1) reduced the blood lead concentration. This effect was observed in lead poisoned rats (p < 0.0001) and also in rats nonpoisoned with lead (p < 0.05). PMID:26075218

  14. Effect of lead pollution control on environmental and childhood blood lead level in Nantong, China: an interventional study.

    Science.gov (United States)

    Chen, Kai; Huang, Lei; Yan, Beizhan; Li, Hongbo; Sun, Hong; Bi, Jun

    2014-11-04

    Children's blood lead levels and prevalence of lead poisoning in China are significantly higher than in developed countries, though a substantial decrease has been observed. Since 2011, strict lead control policies in lead-related industries have been implemented in China, but the success of these policies is unknown. In this study, we collected environmental samples, questionnaire data, and blood samples from 106 children from 1 to 14 years old, before and after implementation of lead-usage control policy in wire rope factories by local government in Zhuhang, Nantong in 2012. Results showed that, one year after the lead control, lead concentrations sharply decreased in both environmental and biological samples with a decrease of 0.43 μg/m3 (-84.3%) in ambient air samples, 0.22 mg/kg (-36.1%) in vegetable samples, 441.1 mg/kg (-43.7%) in dust samples, and 6.24 μg/dL (-51.5%) in childhood blood lead levels (BLL). This study demonstrates the success of lead control policies in promoting the prevention and control of childhood lead poisoning in Nantong, China.

  15. Transition of cord blood lead level, 1985-2002, in the Taipei area and its determinants after the cease of leaded gasoline use

    International Nuclear Information System (INIS)

    Hwang, Y.-H.; Ko Yi; Chiang, C.-D.; Hsu, S.-P.; Lee, Y.-H.; Yu, C.-H.; Chiou, C.-H.; Wang, J.-D.; Chuang, H.-Y.

    2004-01-01

    Lead has long been of concern for its toxicity, impairment of neurobehavioral and cognitive development, and electrophysiological deficits in children, even at levels less than 10 μg/dL. The present study was conducted to elucidate the extent of cord blood lead level decline in the Taipei area from 1985 to 2002 and to explore the factors affecting the cord blood lead level after the cease of leaded gasoline use. In the current study period of 2001-2002, 184 of 1310 newborns delivered in the Taipei Municipal Women and Children Hospital between September 2001 and August 2002 were eligible and randomly selected to participate in this study. Neither of their parents had an occupational lead exposure history. At each delivery, a sample of 5-10 mL umbilical cord blood was collected for lead determination by graphite furnace atomic absorption spectrometry. The cord blood lead level of the newborns in the current study period averaged 2.35±1.12 μg/dL. Together with the cord blood lead averages of 7.48±2.25 and 3.28±1.52 μg/dL obtained from two previous surveys conducted in 1985-1987 and 1990-1992, respectively, the cord blood lead level was significantly decreased (P<0.005). It is estimated that such a reduction in cord blood lead from 7.48 to 2.35 μg/dL for each year's cohort of 260,000 newborns in Taiwan might benefit the economics, ranging from US$8.9 billion to US$12.1 billion by improving the worker productivity. For the time period from 1985 to 2002, there were consistent transition patterns among the yearly fluctuations of air lead level, leaded gasoline consumption, lead content in gasoline, estimated lead amount emitted from the consumed leaded gasoline, and average cord blood lead levels of the three respective study periods. Additionally, every 0.1-g/L reduction in lead content in gasoline might lead to a lowering of cord blood lead level by 1.78 μg/dL. Furthermore, at low level of around 2 μg/dL, a multiple regression analysis demonstrated that

  16. Secular tolerance? : Anti‐Muslim sentiment in Western Europe

    NARCIS (Netherlands)

    Ribberink, E.C.; Achterberg, P.H.J.; Houtman, D.

    2017-01-01

    he literature about secularization proposes two distinct explanations of anti-Muslim sentiment in secularized societies. The first theory understands it in terms of religious competition between Muslims and the remaining minority of orthodox Protestants; the second understands it as resulting from

  17. Blood lead levels and risk factors for lead poisoning among children in Jakarta, Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    Albalak, Rachel; Noonan, Gary; Buchanan, Sharunda; Flanders, W. Dana; Gotway-Crawford, Carol; Blumenthal, Wendy; Curtis, Gerald; McGeehin, Michael A. [Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, 1600 Clifton Rd. Mailstop E-19, Atlanta, GA 30333 (United States); Kim, Dennis; Tan, Regina [Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, 1600 Clifton Rd. Mailstop D-18, Atlanta, GA 30333 (United States); Jones, Robert L. [Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 1600 Clifton Rd. Mailstop F-18, Atlanta, GA 30333 (United States); Sulaiman, Rini [Swisscontact, Jl. Wijaya XII No. 44, Jakarta (Indonesia) 12160

    2003-01-01

    The phase-out of leaded gasoline began in Jakarta, Indonesia on July 1, 2001. We evaluated mean blood lead levels (BLLs) and the prevalence of elevated BLLs of Jakarta school children and assessed risk factors for lead exposure in these children before the beginning of the phase-out activities. The study involved a population-based, cross-sectional blood lead survey that included capillary blood lead sampling and a brief questionnaire on risk factors for lead poisoning. A cluster survey design was used. Forty clusters, defined as primary schools in Jakarta, and 15 2nd- and 3rd-grade children in each cluster were randomly selected for participation in the study. The average age of children in this study was 8.6 years (range 6-12) and the geometric mean BLL of the children was 8.6 {mu}g/dl (median: 8.6 {mu}g/dl; range: 2.6-24.1 {mu}g/dl) (n=397). Thirty-five percent of children had BLLs {>=}10 {mu}g/dl and 2.4% had BLLs {>=}20 {mu}g/dl. Approximately one-fourth of children had BLLs 10-14.9 {mu}g/dl. In multivariate models, level of education of the child's primary caregiver, water collection method, home varnishing and occupational recycling of metals, other than lead, by a family member were predictors of log BLLs after adjustment for age and sex. BLLs of children who lived near a highway or major intersection were significantly higher than those of children who lived near a street with little or no traffic when level of education was not included in the model. Water collection method was a significant predictor of BLLs {>=}10 {mu}g/dl after adjustment for age and sex. BLLs in children in this study were moderately high and consistent with BLLs of children in other countries where leaded gasoline is used. With the phase-out of leaded gasoline, BLLs of children in Jakarta are expected to rapidly decline as they have in other countries that have phased lead out of gasoline.

  18. Blood, urine, and hair kinetic analysis following an acute lead intoxication.

    Science.gov (United States)

    Ho, G; Keutgens, A; Schoofs, R; Kotolenko, S; Denooz, R; Charlier, C

    2011-01-01

    A case of lead exposure resulting from the accidental ingestion of a lead-containing solution is reported. Because of clinical management rapidly performed through chelation therapy by 2,3-dimercaptopropane sulfonate sodium and meso-2,3-dimercaptosuccinic acid, blood lead levels of this 51-year-old patient were moderate (412.9 μg/L) and no clinical symptoms were observed. Numerous blood and urine samples were collected for kinetic analysis of lead elimination. However, we report the first case in which hair samples were analyzed to determine the excretion level of lead after acute intoxication.

  19. Sex, secularism and religious influence in US politics.

    Science.gov (United States)

    Bernstein, Elizabeth; Jakobsen, Janet R

    2010-01-01

    Through an analysis of alliances between secular and religious actors in US politics and a specific case study on anti-trafficking policy, we show that the intertwining of religion and politics in the US comes from two sources: 1) the secular political and cultural institutions of American public life that have developed historically out of Protestantism, and which predominantly operate by presuming Protestant norms and values; and 2) the direct influence on US politics of religious groups and organisations, particularly in the past quarter-century of lobby groups and political action committees identified with conservative evangelical Christianity. The sources of policies that promote gender and sexual inequality in the US are both secular and religious and we conclude that it is inaccurate to assume that religious influence in politics is necessarily conservative or that more secular politics will necessarily be more progressive than the religious varieties.

  20. Effect of low blood lead levels on anaemia indicators and creatinine clearance rate of workers occupationally exposed to lead

    International Nuclear Information System (INIS)

    Memon, F.; Vasandani, A.G.M.

    2009-01-01

    Although recognized and written about centuries, lead toxicity remains an occupational and public health problem of global dimensions. Several studies have demonstrated that clinical and sub clinical effects of lead toxicity at the blood lead levels considered as safe, i.e., below 30 mug/dl in adults and 10 mu g/dl in children. Such studies have received scant attention in the case of lead occupational workers due to the presumption of high blood lead levels in accordance with occupation. In the present study, therefore an attempt was made to investigate the effect of low blood lead levels on indicators of anaemia and renal impairment. A cohort of 690 subjects who had been occupationally exposed to lead was studied using stratified random sampling design. The markers of anaemia included changes in Haematocrit value, Haemoglobin and Erythrocyte count where as renal health was judged from changes in creatinine clearance rate. The controls were derived from similar socioeconomic background and matched in age and sex with subjects. Blood lead levels were determined by graphite furnace atomic absorption and biochemical determinations carried out using standard procedures. Blood lead levels in the range 10-40 mu g/dl had significant effect on anaemia indicators and resulted in inverse co relationship. (Pearson's correlation coefficient r-0.65, -0.71 and -0.58 respectively for haematocrit, erythrocyte count and haemoglobin). The creatinine clearance rate estimated after adjustment for body mass index and age factors was found to depend on blood lead level and duration of exposure of subjects. These effects were statistically significant in the subjects having age in the range 15-30 years. Low lead levels in blood have high potential of inducing lead related anaemia by disturbing the pathway of heme synthesis at either ferrochetalase stage or inhibiting the amino levulinate dehydratase activity. Though creatinine clearance rate did not prove as reliable marker of renal

  1. Blood lead levels of traffic- and gasoline-exposed professionals in the city of Athens

    International Nuclear Information System (INIS)

    Kapaki, E.N.; Varelas, P.N.; Syrigou, A.I.; Spanaki, M.V.; Andreadou, E.; Kakami, A.E.; Papageorgiou, C.T.

    1998-01-01

    During the past 10 y, blood lead levels in the population of Athens, Greece, have decreased steadily. This decrease has paralleled the reduction of tetraethyl lead in gasoline and the introduction of unleaded fuel. Blood lead levels and other parameters were studied in 42 gas-station employees, 47 taxi drivers, 47 bus drivers, and 36 controls, all of whom worked in Athens. The blood lead levels did not differ significantly among the four groups. Glutamic-oxaloacetic transaminase and glutamic-pyruvic transaminase were elevated in gas-station employees, and the former was elevated in taxi drivers. Gas-station employees who smoked had higher blood lead levels than their nonsmoking counterparts. The absence of any difference in the blood lead levels of individuals for whom physical examinations were either normal or abnormal suggests that either lead was not the cause of increased blood lead levels or that its contribution may have been important in the past

  2. Predictors of blood lead levels in agricultural villages practicing wastewater irrigation in Central Mexico.

    Science.gov (United States)

    Cifuentes, E; Villanueva, J; Sanin, L H

    2000-01-01

    To investigate whether the agricultural use of untreated wastewater (i.e. crop irrigation) was associated with elevated blood lead levels in a farming population in the Mezquital Valley and which risk factors, other than exposure to untreated wastewater, were associated with elevated blood lead levels, lead levels were measured in venous blood obtained from 735 individuals. Blood samples were analyzed by atomic absorption spectrophotometry. Food habits and dietary intake were gathered by interview, using a semi-quantitative food-frequency questionnaire. The average blood lead level was 7.8 microg/dL (SD 4.66 microg/dL; range 1.2-36.7 microg/dL). 23% of the study population had blood lead levels exceeding 10 microg/dL. The use of lead-glazed ceramics (LGC) was significantly associated with elevated lead levels (p = workers). p = 0.005, 0.08, and 0.001, respectively. When the analysis was stratified by the use of LGC for food preparation, an inverse relationship between higher daily calcium intake and blood lead level was detected (beta = - 0.040, p = associated with the use of LGC. Calcium intake showed a protective effect, maybe by decreasing absorption of lead in the gastrointestinal tract. No association between occupational exposure to untreated wastewater or crop consumption and blood lead levels was detected. Further environmental and health surveillance is recommended.

  3. Social Boundaries and Secularism in the Lebanese Left

    DEFF Research Database (Denmark)

    Haugbølle, Sune

    2013-01-01

    This article explores the social meaning of boundaries in Lebanon through debates about secularism in and around the Lebanese Left. The aim is to elucidate the political and social meaning of ‘Left’ in a Lebanese context, and the positioning of liminal political subjectivity in a system organized...... along sectarian boundaries. Based on readings of debates about secularism in 1975 and 1976, the article proposes that the Left has since that year been forced to embrace secularism as its primary ideological marker. This experience in turn has become constitutive for what it means to be a leftist...

  4. Relationship Between Total and Biaccessible Lead on Children's Blood Lead Levles in Urban Residential Philadelphia Soils.

    Data.gov (United States)

    U.S. Environmental Protection Agency — Relationship Between Total and Biaccessible Lead on Children's Blood Lead Levles in Urban Residential Philadelphia Soils. This dataset is not publicly accessible...

  5. Really not god: Secularization and pragmatism in Gamblers Anonymous.

    Science.gov (United States)

    Browne, B R

    1994-09-01

    The paper argues that despite maintaining the image of a twelve-step organization, the central theme of the history of Gamblers Anonymous (GA) in the United States is the increasing secularization of the program of the recovery. The paper documents the increasing secularization and pragmatism of Gamblers Anonymous, as reflected in key documents, despite the spiritual vision of its founding member. The author speculates on why Gamblers Anonymous took a secularized development path. Further research is called for.

  6. Association of tibia lead and blood lead with end-stage renal disease: A pilot study of African-Americans

    International Nuclear Information System (INIS)

    Muntner, Paul; Menke, Andy; Batuman, Vecihi; Rabito, Felicia A.; He Jiang; Todd, Andrew C.

    2007-01-01

    The association between body lead burden and kidney disease remains controversial. Fifty-five African-American end-stage renal disease (ESRD) cases and 53 age- and sex-matched African-American controls without known renal disease were recruited from Tulane University-affiliated dialysis clinics and out-patient clinics, respectively. Blood lead was measured via atomic absorption spectrophotometry and tibia lead (a measure of body lead) was measured via 109 Cd-based K shell X-ray fluorescence. Median blood lead levels were significantly higher among ESRD cases (6 μg/dL) compared to their control counterparts (3 μg/dL; P<0.001). Although no participants had overt lead poisoning (blood lead ≥25 μg/dL), seven cases but no controls had blood lead levels above 10 μg/dL (P=0.006). The median tibia lead level was 17 micrograms of lead per gram of bone mineral (μg/g) and 13 μg/g among ESRD cases and their control counterparts, respectively (P=0.134). Four ESRD cases (7%), but no controls, had a tibia lead level above 40 μg/g (P=0.115) while a similar proportion of cases and controls had tibia lead between 20 and 39 μg/g (33% and 32%, respectively; P=0.726). After adjustment for potential confounders, the odds ratios of ESRD associated with a tibia lead ≥20 μg/g and each four-fold higher tibia lead (e.g., 5-20 μg/g) were 1.55 (95% CI: 0.55, 4.41) and 1.88 (95% CI: 0.53, 6.68), respectively. These findings support the need for prospective cohort studies of body lead burden and renal disease progression

  7. Secularization- the promoter of “new type of man”

    Directory of Open Access Journals (Sweden)

    Traian-Alexandru MIU

    2017-06-01

    Full Text Available Secularization is a phenomenon supposing major mutations on the social level. Thus, based on the principle of rationality, secularization has led to the removal of religion from the social sphere, the desacralization, aiming, ultimately, that the sacred disappear altogether from man's life. Within the globalizing-secularizing society, economics seeks to take possession of the entire social and spiritual life, helped by a policy-aggressive mercantile mentality. Secularization has led to manipulation of man so that he believes he has to build his future by abstaining from religion. The secularized man has come to the conclusion that only by his own forces helped by reason, economy and technology he can be the one who creates progress, namely perfection for himself and for the world he lives in. The hypermodern man is a man of ephemerality, a human being looking for his accomplishment in trifles, who no longer has deification as his final goal. The problems that man is facing today can be solved by taking the eternity as reference system for them.

  8. A Pilot Study of Children’s Blood Lead Levels in Mount Isa, Queensland

    Directory of Open Access Journals (Sweden)

    Donna Green

    2017-12-01

    Full Text Available Mount Isa, Queensland, is one of three Australian cities with significant lead emissions due to nonferrous mining and smelting. Unlike the two other cities with lead mines or smelters, Mount Isa currently has no system of annual, systematic, community-wide blood lead level testing; and testing rates among Indigenous children are low. In previous screenings, this group of children has been shown to have higher average blood lead levels than non-Indigenous children. The first aim of this study was to assess whether parents and children would participate in less invasive, rapid point-of-care capillary testing. The second aim was to measure blood lead levels among a range of children that roughly reflected the percentage of the Indigenous/non-Indigenous population. This pilot study is based on a convenience sample of children between the ages of 12 and 83 months who were recruited to participate by staff at a Children and Family Centre. Over three half-days, 30 children were tested using capillary blood samples and the LeadCare II Point-of-Care testing system. Rapid point-of-care capillary testing was well tolerated by the children. Of 30 children tested, 40% (n = 12 had blood lead levels ≥5 µg/dL and 10% had levels ≥10 µg/dL. The highest blood lead level measured was 17.3 µg/dL. The percentage of children with blood lead levels ≥5 µg/dL was higher among Indigenous children compared to non-Indigenous (64.2% compared to 18.8% as was the geometric mean level (6.5 (95% CI, 4.7, 9.2 versus 2.4 (95% CI, 1.8, 3.1, a statistically significant difference. Though based on a small convenience sample, this study identified 12 children (40% of the sample with blood lead levels ≥5 µg/dL. Due to historical and ongoing heavy metal emissions from mining and smelting in Mount Isa, we recommend a multi-component program of universal blood lead level testing, culturally appropriate follow-up and intervention for children who are identified with blood lead

  9. The relationship between blood lead levels and occupational exposure in a pregnant population

    Directory of Open Access Journals (Sweden)

    Osmel La-Llave-León

    2016-12-01

    Full Text Available Abstract Background Pregnant women exposed to lead are at risk of suffering reproductive damages, such as miscarriage, preeclampsia, premature delivery and low birth weight. Despite that the workplace offers the greatest potential for lead exposure, there is relatively little information about occupational exposure to lead during pregnancy. This study aims to assess the association between blood lead levels and occupational exposure in pregnant women from Durango, Mexico. Methods A cross-sectional study was carried out in a population of 299 pregnant women. Blood lead was measured in 31 women who worked in jobs where lead is used (exposed group and 268 who did not work in those places (control group. Chi-square test was applied to compare exposed and control groups with regard to blood lead levels. Odds ratio (OR and 95% confidence intervals (CI were calculated. Multivariable regression analysis was applied to determine significant predictors of blood lead concentrations in the exposed group. Results Exposed women had higher blood lead levels than those in the control group (4.00 ± 4.08 μg/dL vs 2.65 ± 1.75 μg/dL, p = 0.002. Furthermore, women in the exposed group had 3.82 times higher probability of having blood lead levels ≥ 5 μg/dL than those in the control group. Wearing of special workwear, changing clothes after work, living near a painting store, printing office, junkyard or rubbish dump, and washing the workwear together with other clothes resulted as significant predictors of elevated blood lead levels in the exposed group. Conclusions Pregnant working women may be at risk of lead poisoning because of occupational and environmental exposure. The risk increases if they do not improve the use of protective equipment and their personal hygiene.

  10. The relationship between blood lead levels and occupational exposure in a pregnant population.

    Science.gov (United States)

    La-Llave-León, Osmel; Salas Pacheco, José Manuel; Estrada Martínez, Sergio; Esquivel Rodríguez, Eloísa; Castellanos Juárez, Francisco X; Sandoval Carrillo, Ada; Lechuga Quiñones, Angélica María; Vázquez Alanís, Fernando; García Vargas, Gonzalo; Méndez Hernández, Edna Madai; Duarte Sustaita, Jaime

    2016-12-07

    Pregnant women exposed to lead are at risk of suffering reproductive damages, such as miscarriage, preeclampsia, premature delivery and low birth weight. Despite that the workplace offers the greatest potential for lead exposure, there is relatively little information about occupational exposure to lead during pregnancy. This study aims to assess the association between blood lead levels and occupational exposure in pregnant women from Durango, Mexico. A cross-sectional study was carried out in a population of 299 pregnant women. Blood lead was measured in 31 women who worked in jobs where lead is used (exposed group) and 268 who did not work in those places (control group). Chi-square test was applied to compare exposed and control groups with regard to blood lead levels. Odds ratio (OR) and 95% confidence intervals (CI) were calculated. Multivariable regression analysis was applied to determine significant predictors of blood lead concentrations in the exposed group. Exposed women had higher blood lead levels than those in the control group (4.00 ± 4.08 μg/dL vs 2.65 ± 1.75 μg/dL, p = 0.002). Furthermore, women in the exposed group had 3.82 times higher probability of having blood lead levels ≥ 5 μg/dL than those in the control group. Wearing of special workwear, changing clothes after work, living near a painting store, printing office, junkyard or rubbish dump, and washing the workwear together with other clothes resulted as significant predictors of elevated blood lead levels in the exposed group. Pregnant working women may be at risk of lead poisoning because of occupational and environmental exposure. The risk increases if they do not improve the use of protective equipment and their personal hygiene.

  11. Kosovar Society through Secularism and Religion

    Directory of Open Access Journals (Sweden)

    MSc. Dritero Arifi

    2013-12-01

    Full Text Available This paper will analyze the importance and the effects of religion, in Kosovar society. A great part of the paper, will analyze the social and the political relations in Post-War Kosovo. Initially it will elaborate religion and secularism, especially in theoreticall aspect, what impact have these definitions in modern societies. In order to explain what the importance of the religion in Kosovo is, we will focus on analyzing ethnical, social and political relations within Kosovo society. A considerable component of the paper is also, the elaboration of secularism in Kosovo conditions. This implies that the formulation of the problem and the objective of this research, are the substance of the paper’s theme, which is, religion in Kosovo; its definition and the outlook of the Kosovar society on religion. Is Kosovo post-war society more or less religious? That means the elements of Religions and Secularism will be part of the analysis of developments in post-war Kosovo.

  12. The effect of the OSHA lead exposure in construction standard on blood lead levels among iron workers employed in bridge rehabilitation.

    Science.gov (United States)

    Levin, S M; Goldberg, M; Doucette, J T

    1997-03-01

    Over 50,000 workers are at risk of occupational exposure to lead in the course of renovating the nation's deteriorating infrastructure. In mid-1993, to control exposure to lead in the construction setting OSHA promulgated a Lead in Construction Standard. In this study, we assessed the effect of the mandated changes in exposure conditions which followed the introduction of this new standard. We analyzed changes in baseline and maximum blood lead concentrations and in maximum increments in blood lead levels before and after introduction of the standard among iron workers employed in the renovation of a large, lead-painted, steel bridge in New York City. Results indicated that baseline and maximum blood lead levels fell significantly after the implementation of the provisions of the standard, as did maximum increments in blood lead concentrations. Seventy-six percent of the workers maintained blood lead concentrations below 20 micrograms/dl after the OSHA standard, as compared with 66% prior to its implementation. Increments of 20 micrograms/dl or more occurred considerably more frequently before introduction of the standard (13% before vs. 4% after; p = 0.01). Evidence of decreased exposure to lead was observed among iron workers who were present both before and after the introduction of the OSHA standard, as well as among iron workers newly hired after the OSHA provisions were put in place. These findings document the effectiveness of the OSHA construction lead standard in controlling exposure to lead in this complex and variable environment. The data indicate the utility of blood lead determinations in assessing the outcome of industrial hygiene interventions to reduce exposures to lead in the construction setting.

  13. Periodic and secular changes in SS 433

    International Nuclear Information System (INIS)

    Collins, G.W.; Newsom, G.H.

    1983-01-01

    The recent history of SS 433 is reviewed with particular attention being given to the discovery of the periodic phenomena displayed by this object. Several periods ranging from days to months are established as being present in the spectrum of the ''moving'' lines as well as in other aspects of the emission from the object. In addition evidence for secular change in some of the defining parameters of the system is presented. Although these secular changes may eventually prove to be periodic on a rather long time scale, some interpretation of both the periodic and secular phenomena is possible. It is shown that it is possible to interpret all the known periodic phenomena in terms of a processing object responding to the time-varying torques that one would expect in a binary system

  14. Hunting with lead: association between blood lead levels and wild game consumption.

    Science.gov (United States)

    Iqbal, Shahed; Blumenthal, Wendy; Kennedy, Chinaro; Yip, Fuyuen Y; Pickard, Stephen; Flanders, W Dana; Loringer, Kelly; Kruger, Kirby; Caldwell, Kathleen L; Jean Brown, Mary

    2009-11-01

    Wild game hunting is a popular activity in many regions of the United States. Recently, the presence of lead fragments in wild game meat, presumably from the bullets or shot used for hunting, has raised concerns about health risks from meat consumption. This study examined the association between blood lead levels (PbB) and wild game consumption. We recruited 742 participants, aged 2-92 years, from six North Dakota cities. Blood lead samples were collected from 736 persons. Information on socio-demographic background, housing, lead exposure source, and types of wild game consumption (i.e., venison, other game such as moose, birds) was also collected. Generalized estimating equations (GEE) were used to determine the association between PbB and wild game consumption. Most participants reported consuming wild game (80.8%) obtained from hunting (98.8%). The geometric mean PbB were 1.27 and 0.84 microg/dl among persons who did and did not consume wild game, respectively. After adjusting for potential confounders, persons who consumed wild game had 0.30 microg/dl (95% confidence interval: 0.16-0.44 microg/dl) higher PbB than persons who did not. For all game types, recent (game consumption was associated with higher PbB. PbB was also higher among those who consumed a larger serving size (> or = 2 oz vs. game' consumption only. Participants who consumed wild game had higher PbB than those who did not consume wild game. Careful review of butchering practices and monitoring of meat-packing processes may decrease lead exposure from wild game consumption.

  15. Modelling the secular evolution of migrating planet pairs

    Science.gov (United States)

    Michtchenko, T. A.; Rodríguez, A.

    2011-08-01

    The subject of this paper is the secular behaviour of a pair of planets evolving under dissipative forces. In particular, we investigate the case when dissipative forces affect the planetary semimajor axes and the planets move inwards/outwards the central star, in a process known as planet migration. To perform this investigation, we introduce fundamental concepts of conservative and dissipative dynamics of the three-body problem. Based on these concepts, we develop a qualitative model of the secular evolution of the migrating planetary pair. Our approach is based on the analysis of the energy and the orbital angular momentum exchange between the two-planet system and an external medium; thus no specific kind of dissipative forces is invoked. We show that, under the assumption that dissipation is weak and slow, the evolutionary routes of the migrating planets are traced by the Mode I and Mode II stationary solutions of the conservative secular problem. The ultimate convergence and the evolution of the system along one of these secular modes of motion are determined uniquely by the condition that the dissipation rate is sufficiently smaller than the proper secular frequency of the system. We show that it is possible to reassemble the starting configurations and the migration history of the systems on the basis of their final states and consequently to constrain the parameters of the physical processes involved.

  16. Diagnostic use of blood porphyrin and radiographic changes in lead exposure in goats

    International Nuclear Information System (INIS)

    Swarup, D.; Maiti, S.K.; Dwivedi, S.K.

    1990-01-01

    Blood porphyrin, hematological examination and radiographic changes were evaluated for the detection of lead intoxication in goats given daily po doses of 10, 15 and 20 mg lead acetate (5.43, 8.15 and 10.86 mg lead)/kg body weight for 30, 30 and 31 days, or a total of 91 days. Blood porphyrin was found a sensitive indicator with direct correlation (r = 0.976) to blood lead concentration. Basophilic stippling was not seen in the lead-exposed goats. Radiopaque bands developed at the distal metaphysis of the radius in 7 of the 12 lead-exposed goats at day 30. The usefulness of this sign for the diagnosis of lead exposure in goats requires further investigation

  17. The post-secular city

    DEFF Research Database (Denmark)

    Greve, Anni

    ) elements in ritual and ceremonies. Second, emergent spaces of post-secular practices are not only connected to traditional religious sites. With Schmautz (1998) it is necessary to understand a sacred site in its original social and cultural setting, and in the present experience of it. With a point...... in research on trans-national identity making (Fortier 2002). This paper suggests a displacement of focus from trans-national to international identity making and the possible role of religious societies. It is argued that an international culture is not mainstream culture however there are (universal......’ the paper argues for a possible potential of storytelling and mutual recognition. Third, it offers an argument for detecting ‘post-secular sites’ at the urban level from two angles: From architecture (the iconic consciousness) and from performance (the sacred drama). Fourth, the paper closes with a case...

  18. Human Rights Education and the Post Secular Turn

    Science.gov (United States)

    Bowie, Bob

    2012-01-01

    This article questions whether human rights education (HRE) scholarship is responding adequately to the post secular turn in thinking about the place and nature of religion in society. Here the post secular turn is used to describe the discrediting of secularisation theory, the recognition of religion as an enduring and pervasive global cultural…

  19. Individual and environmental risk factors for high blood lead concentrations in Danish indoor shooters.

    Science.gov (United States)

    Grandahl, Kasper; Suadicani, Poul; Jacobsen, Peter

    2012-08-01

    International studies have shown blood lead at levels causing health concern in recreational indoor shooters. We hypothesized that Danish recreational indoor shooters would also have a high level of blood lead, and that this could be explained by shooting characteristics and the physical environment at the shooting range. This was an environmental case study of 58 male and female shooters from two indoor shooting ranges with assumed different ventilation and cleaning conditions. Information was obtained on general conditions including age, gender, tobacco and alcohol use, and shooting conditions: weapon type, number of shots fired, frequency of stays at the shooting range and hygiene habits. A venous blood sample was drawn to determine blood lead concentrations; 14 non-shooters were included as controls. Almost 60% of the shooters, hereof five out of 14 women, had a blood lead concentration above 0.48 micromol/l, a level causing long-term health concern. All controls had blood lead values below 0.17 micromol/l. Independent significant associations with blood lead concentrations above 0.48 micromol/l were found for shooting at a poorly ventilated range, use of heavy calibre weapons, number of shots and frequency of stays at the shooting range. A large proportion of Danish recreational indoor shooters had potentially harmful blood lead concentrations. Ventilation, amounts of shooting, use of heavy calibre weapons and stays at the shooting ranges were independently associated with increased blood lead. The technical check at the two ranges was performed by the Danish Technological Institute and costs were defrayed by the Danish Rifle Association. To pay for the analyses of blood lead, the study was supported by the The Else & Mogens Wedell-Wedellsborg Foundation. The Danish Regional Capital Scientific Ethics Committee approved the study, protocol number H-4-2010-130.

  20. Pilgrimage as post-secular therapy

    Directory of Open Access Journals (Sweden)

    Lisbeth Mikaelsson

    2012-01-01

    Full Text Available This article describes the institutionalized pilgrim role and then turns to the therapeutic discourse which is so prominent in the modern pilgrimage to Santiago de Compostela. Both the role and the discourse can be related to the concept of post-secularity, demonstrating that complex cultural fields such as religion and therapy, become intertwined in new ways through modern pilgrimage. This article also shows that churches cooperating in this type of pilgrimage are adapting to the post-secular age, finding a new sort of raison d’être in a multi-religious, international world. Here the author refers to the Church of Norway and its role in Norwegian pilgrimage. The latter is modelled upon the Santiago example.

  1. Transit Duration Variations due to Secular Interactions in Systems with Tightly-packed Inner Planets

    Science.gov (United States)

    Boley, Aaron; Van Laerhoven, Christa; Granados Contreras, A. Paula

    2018-04-01

    Secular interactions among planets in multi-planet systems will lead to variations in orbital inclinations and to the precession of orbital nodes. Taking known system architectures at face value, we calculate orbital precession rates for planets in tightly-packed systems using classical second-order secular theory, in which the orientation of the orbits can be described as a vector sum of eigenmodes and the eigenstructure is determined only by the masses and semi-major axes of the planets. Using this framework, we identify systems that have fast precession frequencies, and use those systems to explore the range of transit duration variation that could occur using amplitudes that are consistent with tightly-packed planetary systems. We then further assess how transit duration variations could be used in practice.

  2. The „Pussy riot“ case and the post-secular hybrids

    Directory of Open Access Journals (Sweden)

    Uzlaner Dmitrij

    2013-01-01

    Full Text Available The article is devoted to the analysis of the “Pussy riot” case and the peculiarities of Russian postsecularism. Special emphasis is placed on the phenomenon of post-secular hybrids, i.e. the overcoming of the situation of social differentiation between religion and other social subsystems (one of the main distinctive features of secularization. It is claimed that the materials of the trial against “Pussy riot” make evident the appearance in Russia of at least three post-secular hybrids: 1 the blending of religion and politics; 2 installation of religious norms into the public order of the secular state; 3 significance of confessional legal experts as part of the new “ideological state apparatus”.

  3. Effect on blood lead of airborne lead particles characterized by size.

    Science.gov (United States)

    Park, Dong-Uk; Paik, Nam-Won

    2002-03-01

    Worker exposure to airborne lead particles was evaluated for a total of 117 workers in 12 work-places of four different industrial types in Korea. The particle sizes were measured using 8-stage cascade impactors worn by the workers. Mass median aerodynamic diameters (MMAD) were determined by type of industry and percentage of lead particles as a fraction of airborne lead (PbA) concentration was determined by particle size. Blood lead (PbB) levels of workers who matched airborne lead samples were also examined. A Scheffé's pairwise comparison test showed that MMAD and the fractions of each of respirable particles and lead particles lead particles lead particles (r = 0.82) than that between concentrations of small particles and PbA (r = 0.61). A simple linear regression indicated that PbB correlated better with respirable lead concentration (r2 = 0.35, P = 0.0001) than with PbA concentration and had a higher slope coefficient. Controlling for respirable lead concentration reduced the partial correlation coefficient between PbA concentration and PbB level from 0.56 to 0.20 (P = 0.053). The results indicate that the contribution of respirable lead particles to lead absorption would be greater than that of PbA. This study concludes that the measurement of PbA only may not properly reflect a worker's exposure to lead particles with diverse characteristics. For the evaluation of a worker's exposure to various types of lead particles, it is recommended that respirable lead particles as well as PbA be measured.

  4. Isotopic ratio based source apportionment of children's blood lead around coking plant area.

    Science.gov (United States)

    Cao, Suzhen; Duan, Xiaoli; Zhao, Xiuge; Wang, Beibei; Ma, Jin; Fan, Delong; Sun, Chengye; He, Bin; Wei, Fusheng; Jiang, Guibin

    2014-12-01

    Lead exposure in the environment is a major hazard affecting human health, particularly for children. The blood lead levels in the local children living around the largest coking area in China were measured, and the source of blood lead and the main pathways of lead exposure were investigated based on lead isotopic ratios ((207)Pb/(206)Pb and (208)Pb/(206)Pb) in blood and in a variety of media, including food, airborne particulate matter, soil, dust and drinking water. The children's blood lead level was 5.25 (1.59 to 34.36 as range) μg dL(-1), lower than the threshold in the current criteria of China defined by the US Centers for Disease Control (10 μg dL(-1)). The isotopic ratios in the blood were 2.111±0.018 for (208)Pb/(206)Pb and 0.864±0.005 for (207)Pb/(206)Pb, similar to those of vegetables, wheat, drinking water, airborne particulate matter, but different from those of vehicle emission and soil/dust, suggesting that the formers were the main pathway of lead exposure among the children. The exposure pathway analysis based on the isotopic ratios and the human health risk assessment showed that dietary intake of food and drinking water contributed 93.67% of total exposed lead. The study further indicated that the coal used in the coking plant is the dominant pollution source of lead in children's blood. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. BLOOD LEAD AND SECONDARY SEXUAL CHARACTERISTICS AND MENSES IN U.S. GIRLS

    Science.gov (United States)

    Blood Lead and Secondary Sexual Characteristics and Menses in U.S. Girls. *T. Wu, P. Mendola, and G.M. Buck (SUNY at Buffalo, Buffalo, NY 14214)Purpose: To investigate the association between blood lead and puberty (presence of public hair, breast development, and menarch...

  6. RELIGIOUS QUESTION AND SECULAR STATE: CRISIS OF REGULATION BY DANI LE HERVIEU-L GER

    Directory of Open Access Journals (Sweden)

    S. V. Trophimov

    2017-01-01

    Full Text Available The proposed paper outlines concepts of the Religious individualism in modern Western society analyzed by the French sociologist Danièle Hervieu-Léger in “Religion in movement (1999”. Author proposes an assessment of the religious situation in the French society at the end of the XX century and discuss some examples. Particular attention is given to crisis of secular regulation of the religious in the modern society. The weakening of the regulatory capacity of religious institutions leads to a weakening of the secular state. Religious institutions should be able to implement the regime of the truth of faith, which makes the institutional power of the superior guarantor of common faith principles shared by all believers of the denomination. The system of “copying” the structures of the Catholic Church of the XVIII century adopted by the secular state, today is not more correspond nor religious organizations in general, neither even the modern structures of the organization of the Catholic Church in France, that become a problem for a state-confessional relation. Modern institutional disorganization in the religious field, contributing to the destabilization of the French model of secularism, weakened by political cultural and economic liberalization that undermine its principles values that historically based secular system itself. Institutional crisis of the truths of faith approval favours an increase in the number of belief systems of individual communities. The problem can not be solved a priori, legally separating the traditional, “recognized by law” and other religions. The changing religious situation the state must find a new model of interaction with religious groups and organizations. The material is useful for comparative studies of the religious situation in Russia and Western Europe.

  7. Blood lead and preeclampsia: A meta-analysis and review of implications.

    Science.gov (United States)

    Poropat, Arthur E; Laidlaw, Mark A S; Lanphear, Bruce; Ball, Andrew; Mielke, Howard W

    2018-01-01

    Multiple cross-sectional studies suggest that there is an association between blood lead and preeclampsia. We performed a systematic review and meta-analysis to summarize information on the association between preeclampsia and lead poisoning. Searches of Medline, Web of Science, Scopus, Pubmed, Science Direct and ProQuest (dissertations and theses) identified 2089 reports, 46 of which were downloaded after reviewing the abstracts, and 11 studies were evaluated as meeting the selection criteria. Evaluation using the ROBINS-I template (Sterne, et al., 2016), indicated moderate risk of bias in all studies. We found that blood lead concentrations were significantly and substantially associated with preeclampsia (k = 12; N = 6069; Cohen's d = 1.26; odds ratio = 9.81; odds ratio LCL = 8.01; odds ratio UCL = 12.02; p = 0.005). Eliminating one study produced a homogeneous meta-analysis and stronger estimates, despite the remaining studies coming from eight separate countries and having countervailing risks of bias. Blood lead concentrations in pregnant women are a major risk factor for preeclampsia, with an increase of 1μg/dL associated with a 1.6% increase in likelihood of preeclampsia, which appears to be the strongest risk factor for preeclampsia yet reported. Pregnant women with historical lead exposure should routinely have blood lead concentrations tested, especially after mid-term. Women with concentrations higher than 5μg/dL should be actively monitored for preeclampsia and be advised to take prophylactic calcium supplementation. All pregnant women should be advised to actively avoid lead exposure. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Secularization and de-secularization processes under the light of Max Weber’s rationalization sociology

    Directory of Open Access Journals (Sweden)

    Eduardo Weisz

    2017-10-01

    Full Text Available This article starts posing a number of problems with which the classical understanding of the end of religions in Modernity has been confronted. This allows for a framework from which Max Weber’s theory of secularization can be addressed. From 1904 onwards, this author was engaged in the understanding of the historical-universal process of rationalization, and it is in this analysis where his prospective of secularization has to be looked for. His sociology of religion is therefore deconstructed from this point of view, so as to grasp why he understood that religions were displaced in the constitution of modern life conducts. After this analysis, the article poses the importance of this author’s legacy for the understanding of different issues concerning the present process of rebirth of religions.

  9. A model for solar constant secular changes

    Science.gov (United States)

    Schatten, Kenneth H.

    1988-01-01

    In this paper, contrast models for solar active region and global photospheric features are used to reproduce the observed Active Cavity Radiometer and Earth Radiation Budget secular trends in reasonably good fashion. A prediction for the next decade of solar constant variations is made using the model. Secular trends in the solar constant obtained from the present model support the view that the Maunder Minimum may be related to the Little Ice Age of the 17th century.

  10. A few more comments on secularly growing loop corrections in strong electric fields

    International Nuclear Information System (INIS)

    Akhmedov, E.T.; Popov, F.K.

    2015-01-01

    We extend the observations of our previous paper http://dx.doi.org/10.1007/JHEP09(2014)071 [http://arxiv.org/abs/1405.5285]. particular, we show that the secular growth of the loop corrections to the two-point correlation functions is gauge independent: we observe the same growth in the case of the static gauge for the constant background electric field. Furthermore we solve the kinetic equation describing photon production from the background fields, which was derived in our previous paper and allows one to sum up leading secularly growing corrections from all loops. Finally, we show that in the constant electric field background the one-loop correction to the current of the produced pairs is not zero: it also grows with time and violates time translational and reversal invariance of QED on the constant electric field background.

  11. Determinants of maternal and umbilical blood lead levels: a cross-sectional study, Mosul, Iraq

    Directory of Open Access Journals (Sweden)

    Al-Jomard Raghad A

    2009-03-01

    Full Text Available Abstract Background The populations who are most sensitive to lead exposure from various sources are pregnant women and their newborns. Aiming to explore the presence of correlation between maternal and cord blood lead levels and to identify potential predictors that may influence both levels, the present study has been conducted. Methods A cross-sectional study was conducted covering 350 full terms maternal-newborns pairs from Mosul maternity hospitals. Data were obtained directly from women just before delivery by the use of a detailed questionnaire form. Maternal and umbilical blood lead levels were estimated using LEADCARE® Blood Lead Testing System and Kits. Results A positive significant correlation was found between maternal and cord blood lead values (r = 0.856, p = 0.001. By backward stepwise logistic regression analysis the followings emerged as significant potential predictors of high maternal blood lead: low parity, smoking and Hb level Conclusion Study results have provided baseline data needed to be transformed to decision makers to implement measures to eliminate lead from the environment and protect future generation from its deleterious effects.

  12. The Jesuit Imaginary: Higher Education in a Secular Age

    Science.gov (United States)

    Hendrickson, Daniel Scott

    2012-01-01

    The philosopher Charles Taylor argues in "A Secular Age" (2007) that people who live in secular cultures are losing the capacity to experience genuine "fullness." Described by Taylor as a philosophical-anthropological conception of human flourishing that corresponds with existential senses of meaning and purpose, fullness is…

  13. Evaluating secular acceleration in geomagnetic field model GRIMM-3

    Science.gov (United States)

    Lesur, V.; Wardinski, I.

    2012-12-01

    Secular acceleration of the magnetic field is the rate of change of its secular variation. One of the main results of studying magnetic data collected by the German survey satellite CHAMP was the mapping of field acceleration and its evolution in time. Questions remain about the accuracy of the modeled acceleration and the effect of the applied regularization processes. We have evaluated to what extent the regularization affects the temporal variability of the Gauss coefficients. We also obtained results of temporal variability of the Gauss coefficients where alternative approaches to the usual smoothing norms have been applied for regularization. Except for the dipole term, the secular acceleration of the Gauss coefficients is fairly well described up to spherical harmonic degree 5 or 6. There is no clear evidence from observatory data that the spectrum of this acceleration is underestimated at the Earth surface. Assuming a resistive mantle, the observed acceleration supports a characteristic time scale for the secular variation of the order of 11 years.

  14. Blood Lead, Bone Turnover, and Survival in Amyotrophic Lateral Sclerosis.

    Science.gov (United States)

    Fang, Fang; Peters, Tracy L; Beard, John D; Umbach, David M; Keller, Jean; Mariosa, Daniela; Allen, Kelli D; Ye, Weimin; Sandler, Dale P; Schmidt, Silke; Kamel, Freya

    2017-11-01

    Blood lead and bone turnover may be associated with the risk of amyotrophic lateral sclerosis (ALS). We aimed to assess whether these factors were also associated with time from ALS diagnosis to death through a survival analysis of 145 ALS patients enrolled during 2007 in the National Registry of Veterans with ALS. Associations of survival time with blood lead and plasma biomarkers of bone resorption (C-terminal telopeptides of type I collagen (CTX)) and bone formation (procollagen type I amino-terminal peptide (PINP)) were estimated using Cox models adjusted for age at diagnosis, diagnostic certainty, diagnostic delay, site of onset, and score on the Revised ALS Functional Rating Scale. Hazard ratios were calculated for each doubling of biomarker concentration. Blood lead, plasma CTX, and plasma PINP were mutually adjusted for one another. Increased lead (hazard ratio (HR) = 1.38; 95% confidence interval (CI): 1.03, 1.84) and CTX (HR = 2.03; 95% CI: 1.42, 2.89) were both associated with shorter survival, whereas higher PINP was associated with longer survival (HR = 0.59; 95% CI: 0.42, 0.83), after ALS diagnosis. No interactions were observed between lead or bone turnover and other prognostic indicators. Lead toxicity and bone metabolism may be involved in ALS pathophysiology. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health 2017. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  15. Secular Islam and the Rhetoric of Humanity

    OpenAIRE

    Kharputly, Nadeen Sh B

    2017-01-01

    Secular Islam and the Rhetoric of Humanity” examines competing notions of humanity in representations of Islam in the United States from the Civil Rights period to the present. In post-9/11 representations, Islam is rhetorically “humanized” by the dominant culture in attempts to determine Islam’s role in the United States. This humanizing framework not only presumes an inherent lack of humanity in Islam; it establishes the ideal of the human as white, rational, and secular. To critique this ...

  16. Secular trends of blood pressure in A-bomb survivors

    International Nuclear Information System (INIS)

    Sasaki, Hideo; Kodama, Kazunori; Kitano, Koei

    1986-01-01

    There has been controversy about whether or not radiation exposure plays a major role in advancing age. To preliminarily study this relationship, a statistical analysis was made on blood pressure measurements in a cohort of A-bomb survivors for Adult Health Study carried out during a 22-year period from 1958 through 1980. Systolic blood pressure increased with advancing age in both men and women between 30 and 80 years. During the years 1974 through 1980, it tended to increase in both men and women aged in their thirties and fourties. Diastolic blood pressure for men increased between the ages of 30 and 60 years, and decreased between the ages of 60 and 80 years. It tended to increase from year to year for men. For women, it decreased prior to the 1970's, and thereafter, tended to increase. The parameters, including systolic and diastolic blood pressures and pulse pressure, were independent of exposure doses in the subgroups according to age or sex. (Namekawa, K.)

  17. Comparison of two methods for blood lead analysis in cattle: graphite-furnace atomic absorption spectrometry and LeadCare(R) II system.

    Science.gov (United States)

    Bischoff, Karyn; Gaskill, Cynthia; Erb, Hollis N; Ebel, Joseph G; Hillebrandt, Joseph

    2010-09-01

    The current study compared the LeadCare(R) II test kit system with graphite-furnace atomic absorption spectrometry for blood lead (Pb) analysis in 56 cattle accidentally exposed to Pb in the field. Blood Pb concentrations were determined by LeadCare II within 4 hr of collection and after 72 hr of refrigeration. Blood Pb concentrations were determined by atomic absorption spectrometry, and samples that were coagulated (n = 12) were homogenized before analysis. There was strong rank correlation (R(2) = 0.96) between atomic absorption and LeadCare II (within 4 hr of collection), and a conversion formula was determined for values within the observed range (3-91 mcg/dl, although few had values >40 mcg/dl). Median and mean blood pb concentrations for atomic absorption were 7.7 and 15.9 mcg/dl, respectively; for LeadCare II, medians were 5.2 mcg/dl at 4 hr and 4.9 mcg/dl at 72 hr, and means were 12.4 and 11.7, respectively. LeadCare II results at 4 hr strongly correlated with 72 hr results (R(2) = 0.96), but results at 72 hr were lower (P atomic absorption. Although there have been several articles that compared LeadCare with other analytical techniques, all were for the original system, not LeadCare II. The present study indicated that LeadCare II results correlated well with atomic absorption over a wide range of blood Pb concentrations and that refrigerating samples for up to 72 hr before LeadCare II analysis was acceptable for clinical purposes.

  18. Ethical Issues in Using Children's Blood Lead Levels as a Remedial Action Objective

    Science.gov (United States)

    Evans, Emily Lorraine

    2011-01-01

    The Environmental Protection Agency measures the success or failure of Superfund site remediation efforts against remedial action objectives (RAOs). RAOs are frequently based on environmental contaminant concentrations, but with lead exposure, blood lead levels from the population at risk are often used. Although childhood lead screening is an important public health tool, an RAO based on child blood lead levels raises ethical concerns: public health efforts that are more reactive than preventive, a blood lead standard (10 μg/dL) that may not be fully protective, the use of a measure whose validity and reliability may be easily compromised, and exacerbation of environmental injustice and systematic disadvantages. The example of Bunker Hill mine, Kellogg, Idaho, allowed an examination of these ethical concerns. PMID:21836120

  19. CHILDHOOD BLOOD LEAD LEVELS NOT AFFECTED BY HOUSING COMPLIANCE STATUS

    Science.gov (United States)

    In a secondary analysis of data from the Childhood Lead Poisoning Prevention Program of Philadelphia (July 1, 1999 through September 1, 2004), the authors evaluated the effect of housing compliance status and time to achieve compliance on changes in children's blood lead levels. ...

  20. Contrasting irreligious orientation: atheism and secularity in the USA and Scandinavia

    Directory of Open Access Journals (Sweden)

    Phil Zuckerman

    2012-06-01

    Full Text Available Atheism and secularity are not static, fixed orientations. Rather, atheism and secularity are contoured, malleable, and deeply shaped by cultural and social forces. A clear example of the degree to which atheism and secularity can be lived and expressed quite differently in different socio-cultural locations is revealed by comparing and contrasting the ways in which they are manifested in the United States and Scandinavia.

  1. SECULAR GRAVITATIONAL INSTABILITY OF A DUST LAYER IN SHEAR TURBULENCE

    International Nuclear Information System (INIS)

    Michikoshi, Shugo; Kokubo, Eiichiro; Inutsuka, Shu-ichiro

    2012-01-01

    We perform a linear stability analysis of a dust layer in a turbulent gas disk. Youdin investigated the secular gravitational instability (GI) of a dust layer using hydrodynamic equations with a turbulent diffusion term. We obtain essentially the same result independently of Youdin. In the present analysis, we restrict the area of interest to small dust particles, while investigating the secular GI in a more rigorous manner. We discuss the time evolution of the dust surface density distribution using a stochastic model and derive the advection-diffusion equation. The validity of the analysis by Youdin is confirmed in the strong drag limit. We demonstrate quantitatively that the finite thickness of a dust layer weakens the secular GI and that the density-dependent diffusion coefficient changes the growth rate. We apply the results obtained to the turbulence driven by the shear instability and find that the secular GI is faster than the radial drift when the gas density is three times as large as that in the minimum-mass disk model. If the dust particles are larger than chondrules, the secular GI grows within the lifetime of a protoplanetary disk.

  2. Human exposure to pollutants - part: 1 blood lead and cadmium in a sample of population of Karachi

    International Nuclear Information System (INIS)

    Yousufzai, A.H.K.; Khalid, Q.; Sultana, L.

    1994-01-01

    A study was carried out to see the blood lead and cadmium levels in fifty employees working at PCSIR Laboratories Complex, Karachi. These employees belonged to various socio-economic groups and had their residences in different areas of Karachi. Sixty two percent staff had blood lead level between 100-200 micro g/L. The highest blood lead level(>400 micro g/L) was found in volunteers working as garage staff. No significant difference was found between the blood lead levels of volunteers belonging to different socio-economic and age groups, only 8% of the staff had blood lead levels below 100 micro g/L. Lead in the dust collected from the residences of the volunteers was also estimated for lead and correlated with blood lead levels. Blood cadmium levels were also estimated. These were found to be higher in smokers and tobacco chewers. A definite correlation was observed between blood cadmium levels and smoking habits. (author)

  3. Relationship Between Total and Bioaccessible Lead on Children’s Blood Lead Levels in Urban Residential Philadelphia Soils

    Science.gov (United States)

    Relationships between total soil or bioaccessible lead (Pb), measured using an in vitro bioaccessibility assay, and children’s blood lead levels (BLL) were investigated in an urban neighborhood in Philadelphia, Pennsylvania, USA, with a history of soil Pb contamination....

  4. Levels of blood lead in Griffon vultures from a Wildlife Rehabilitation Center in Spain.

    Science.gov (United States)

    González, Fernando; López, Irene; Suarez, Laura; Moraleda, Virginia; Rodríguez, Casilda

    2017-09-01

    Lead is considered a highly toxic contaminant with important impacts to bird wildlife. Griffon vultures (Gyps fulvus) are a sensitive indicator of the level of environmental contamination due to their position at the top of the food chain and their dependence on human activities. The aim of this study was to assess susceptibility to lead intoxication in Griffon vultures admitted to Wildlife Rehabilitation Centers (WRC), measuring blood lead levels and determining if blood lead concentrations are related to clinical signs, hematological, biochemical or radiographic findings. Also, the influence of age, gender, body condition, season and primary cause of admission were evaluated. This study was realized in all Griffon vultures admitted during a period of one year in the Rehabilitation Center GREFA. Blood lead levels are measured by using anodic stripping voltammetry. In Griffon vultures, we observed that 26% of the analyzed birds presented lead levels above 20µg/dL with 74% below 20µg/dL ([Pb] lead according to sex, season of admission to the center and body condition. A negative correlation was found between levels of metal and hematocrit. No association was found between clinical signs and blood lead levels in Griffon vultures, except for digestive signs as stasis and weight loss. On numerous occasions, the intoxication in this specie is related to ingestion of lead ammunition; however, we have not detected radiographic lead in our vultures. Compared with other studies, we generally found low levels of lead in blood of Griffon vultures but the blood of all birds admitted to WRC presented detectable lead concentrations. This species apparently presents a higher sensibility to the toxic effects of this metal than that described by other authors. It have been observed that there is some evidence that suggests that subclinical levels of lead could be related with a predisposition to injury or diseases, even though these birds might be admitted for other causes. The

  5. New methods for deriving cometary secular light curves: C/1995 O1 (Hale-Bopp) revisited

    Science.gov (United States)

    Womack, Maria; Lastra, Nathan; Harrington, Olga; Curtis, Anthony; Wierzchos, Kacper; Ruffini, Nicholas; Charles, Mentzer; Rabson, David; Cox, Timothy; Rivera, Isabel; Micciche, Anthony

    2017-10-01

    We present an algorithm for reducing scatter and increasing precision in a comet light curve. As a demonstration, we processed apparent magnitudes of comet Hale-Bopp from 16 highly experienced observers (archived with the International Comet Quarterly), correcting for distance from Earth and phase angle. Different observers tend to agree on the difference in magnitudes of an object at different distances, but the magnitude reported by observer is shifted relative to that of another for an object at a fixed distance. We estimated the shifts using a self-consistent statistical approach, leading to a sharper light curve and improving the precision of the measured slopes. The final secular lightcurve for comet Hale-Bopp ranges from -7 au (pre-perihelion) to +8 au (post-perihelion) and is the best secular light curve produced to date for this “great” comet. We discuss Hale-Bopp’s lightcurve evolution and possibly related physical implications, and potential usefulness of this light curve for comparisons with other future bright comets. We also assess the appropriateness of using secular lightcurves to characterize dust production rates in Hale-Bopp and other dust-rich comets. M.W. acknowledges support from NSF grant AST-1615917.

  6. The New Secular Humanists: Ronald Dworkin and Philip Kitcher on Life without God

    Directory of Open Access Journals (Sweden)

    Charles Taliaferro

    2015-07-01

    Full Text Available Ronald Dworkin and Philip Kitcher recognize that traditional, religious faith—especially in Christian theistic tradition—has virtues that seem to be missing in a secular worldview. To remedy this apparent deficit, they both propose that a secular worldview can provide a satisfying foundation for a flourishing, meaningful life. Moreover, Kitcher argues that secular humanism is far more justified than a religious worldview because it does not face the problem of diversity that arises in the case of religion. I argue that secular humanism faces the same problem of diversity that Kitcher proposes undermines religious belief. I further argue that Dworkin’s and Kitcher’s secular alternative to a religious worldview is problematic.

  7. Correlation between blood lead concentration and iron deficiency in ...

    African Journals Online (AJOL)

    Results: We studied 223 cases including 98 control children and 125 patients. All children had lead intoxication. Mean (±SD) blood lead concentration in the control group was 57.1 ± 25.3 (ranged 20-212) μg/dl and in the patient group was 57 ± 20.4 (ranged 10.9-159) μg/dl with no significant difference (P value = 0.713).

  8. Peripheral blood signatures of lead exposure.

    Directory of Open Access Journals (Sweden)

    Heather G LaBreche

    Full Text Available BACKGROUND: Current evidence indicates that even low-level lead (Pb exposure can have detrimental effects, especially in children. We tested the hypothesis that Pb exposure alters gene expression patterns in peripheral blood cells and that these changes reflect dose-specific alterations in the activity of particular pathways. METHODOLOGY/PRINCIPAL FINDING: Using Affymetrix Mouse Genome 430 2.0 arrays, we examined gene expression changes in the peripheral blood of female Balb/c mice following exposure to per os lead acetate trihydrate or plain drinking water for two weeks and after a two-week recovery period. Data sets were RMA-normalized and dose-specific signatures were generated using established methods of supervised classification and binary regression. Pathway activity was analyzed using the ScoreSignatures module from GenePattern. CONCLUSIONS/SIGNIFICANCE: The low-level Pb signature was 93% sensitive and 100% specific in classifying samples a leave-one-out crossvalidation. The high-level Pb signature demonstrated 100% sensitivity and specificity in the leave-one-out crossvalidation. These two signatures exhibited dose-specificity in their ability to predict Pb exposure and had little overlap in terms of constituent genes. The signatures also seemed to reflect current levels of Pb exposure rather than past exposure. Finally, the two doses showed differential activation of cellular pathways. Low-level Pb exposure increased activity of the interferon-gamma pathway, whereas high-level Pb exposure increased activity of the E2F1 pathway.

  9. Oxidative stress and neurological disorders in relation to blood lead levels in children.

    Science.gov (United States)

    Ahamed, M; Fareed, Mohd; Kumar, A; Siddiqui, W A; Siddiqui, M K J

    2008-01-01

    Oxidative stress plays a pivotal role in the pathogenesis of neurological disorders. Free radical generation appears to be the mode of lead toxicity. We evaluated the effects of blood lead levels on oxidative stress parameters in children suffering from neurological disorders. Thirty children (aged 3-12 years) with neurological disorders (cerebral palsy [n = 12], seizures [n = 11], and encephalopathy [n = 7]) were recruited in the study group. Sixty healthy children (aged 3-12 years) from similar socio-economic environments and not suffering from any chronic disease were taken as the controls. Blood lead levels and oxidant/antioxidant status were determined. Mean blood lead level was significantly higher while delta-aminolevulinic acid dehydratase (delta-ALAD) activity, a biomarker for lead exposure, was significantly lower in the study group as compared to the control group (P children with neurological disorders. Lead-induced oxidative stress as an underlying mechanism for neurological diseases in children warranted further investigation.

  10. Interlaboratory Comparison of Lead and Cadmium in Blood, Urine, and Aqueous Solutions

    DEFF Research Database (Denmark)

    Paulev, P. E.; Solgaard, Per Bent; Tjell, Jens Christian

    1978-01-01

    Analysis for lead and cadmium in biological liquids (blood and urine) is difficult. Results of such analyses from five laboratories are compared for samples with known additions of lead and cadmium. The data, evaluated in terms of inter- and intralaboratory reproducibility and accuracy, suggest t...... that laboratories should voluntarily participate in quality control programs. Users of routine laboratories are advised to use their own quality control program......Analysis for lead and cadmium in biological liquids (blood and urine) is difficult. Results of such analyses from five laboratories are compared for samples with known additions of lead and cadmium. The data, evaluated in terms of inter- and intralaboratory reproducibility and accuracy, suggest...

  11. Tendência secular em estatura: uma revisão da literatura Secular height trend: a literature review

    Directory of Open Access Journals (Sweden)

    Gilberto Kac

    1999-09-01

    Full Text Available Esse trabalho constitui-se em uma revisão de literatura sobre tendência secular em estatura (TSE. Os principais tópicos abordados foram a definição do fenômeno, a utilização de dados históricos de estatura como estratégia alternativa no monitoramento de mudanças econômicas, as principais explicações teóricas sugeridas para a ocorrência do fenômeno, o início da antropometria militar, sua utilização no passado e no presente, e a magnitude da tendência em recrutas e na população infantil. Os principais achados revelaram que a TSE tem sido atribuída, sobretudo, a influências ambientais, em particular, a melhorias nas condições sanitárias, econômicas e sociais. As taxas médias de incremento variaram conforme a idade, o estrato sócio-econômico e o país considerado; portanto, deve-se ter cautela nas comparações interpopulacionais. A Segunda Guerra Mundial reduziu a tendência em diversos países, entre eles o Brasil, mas as taxas de incremento no pós-guerra foram ainda maiores do que as observadas no início do século. Constatou-se, por fim, que dados provenientes da antropometria militar são os mais utilizados para estimativas de TSE.This paper presents a literature review of secular height trends. The principal topics included were definition of the phenomenon, use of historical data sets on height as an alternative approach for monitoring economic changes, the main theoretical explanations of the phenomenon, the beginning of military anthropometry, and past and current use in measuring secular height trends in recruits and children. The most important results showed that the positive secular trend can be attributed to environmental influences, especially improvements in health, economic, and social conditions. The mean reported rates in height increases varied with age, socioeconomic status, and country, so one must exercise caution in drawing inferences. World War II slowed the trend in several countries

  12. Impacts of Elevated Prenatal Blood Lead on Trace Element Status and Pregnancy Outcomes in Occupationally Non-exposed Women

    Directory of Open Access Journals (Sweden)

    EI Ugwuja

    2011-06-01

    Full Text Available Background: Lead toxicity has been reported to affect hematopoietic, nervous, reproductive, cardiovascular and urinary tract systems. Many investigators have so far studied the effects of high blood lead levels on pregnancy outcomes. Objective: To investigate the effects of elevated maternal blood lead during pregnancy on some trace elements and pregnancy outcomes. Methods: Blood lead and plasma copper, iron and zinc were measured in 349 pregnant women with a mean±SD age of 27.0±4.8 years, and gestational age of 21.8±3.1 weeks, at recruitment using atomic absorption spectrophotometer. Maternal and fetal outcomes were recorded during follow-up and at delivery, respectively. A blood lead level of ≥10 µg/dL was considered high. Results: Women with elevated blood lead had significantly higher plasma copper and iron and lower plasma zinc than women with low blood lead level (<10 µg/dL. Blood lead level correlated with maternal hemoglobin concentration (r=‑0.1054, p=0.051 and total white blood cell count (r=0.1045, p=0.053. Hypertension, malaria and low birth weight were significantly higher (p<0.05 in women with elevated blood lead than in those with low blood lead level. Conclusion: Complications of pregnancy may be induced by a high blood lead level possibly through the alterations in trace element metabolism.

  13. Secular Volunteerism among Texan Emerging Adults: Exploring Pathways of Childhood and Adulthood Religiosity

    Directory of Open Access Journals (Sweden)

    Reed T. DeAngelis

    2016-06-01

    Full Text Available Prior research suggests that religiosity, especially public religious participation, is related to greater volunteerism. However, less is known about religious transmission across the life course, in particular whether and how religiosity in childhood is linked to later life volunteerism. This study investigates a sample of emerging adults in South Texas (n = 701 with a high percent of Hispanic Americans (53 percent. Specifically, we examine pathways of childhood and emerging adulthood religiosity leading to secular volunteerism. Findings indicate that both childhood and emerging adulthood religiosity are associated with greater volunteerism, but the effects of childhood religiosity on emerging adulthood volunteerism are mediated through emerging adulthood religiosity. These findings provide further confirmation of the importance of childhood religiosity only insofar as religiousness persists into adulthood. In other words, we find that it is emerging adulthood religiosity that transmits childhood religiosity into greater secular volunteerism in later life. Furthermore, emerging adulthood public religiosity has the most robust direct effects on volunteerism.

  14. Environmental lead exposure is associated with visit-to-visit systolic blood pressure variability in the US adults.

    Science.gov (United States)

    Faramawi, Mohammed F; Delongchamp, Robert; Lin, Yu-Sheng; Liu, Youcheng; Abouelenien, Saly; Fischbach, Lori; Jadhav, Supriya

    2015-04-01

    The association between environmental lead exposure and blood pressure variability, an important risk factor for cardiovascular disease, is unexplored and unknown. The objective of the study was to test the hypothesis that lead exposure is associated with blood pressure variability. American participants 17 years of age or older from National Health and Nutrition Examination Survey III were included in the analysis. Participants' blood lead concentrations expressed as micrograms per deciliter were determined. The standard deviations of visit-to-visit systolic and diastolic blood pressure were calculated to determine blood pressure variability. Multivariable regression analyses adjusted for age, gender, race, smoking and socioeconomic status were employed. The participants' mean age and mean blood lead concentration were 42.72 years and 3.44 mcg/dl, respectively. Systolic blood pressure variability was significantly associated with environmental lead exposure after adjusting for the effect of the confounders. The unadjusted and adjusted means of visit-to-visit systolic blood pressure variability and the β coefficient of lead exposure were 3.44, 3.33 mcg/dl, β coefficient = 0.07, P variability. Screening adults with fluctuating blood pressure for lead exposure could be warranted.

  15. Determinants of blood-lead levels in children in Callao and Lima metropolitan area

    Directory of Open Access Journals (Sweden)

    Espinoza Rocío

    2003-01-01

    Full Text Available OBJECTIVES: To determine blood lead levels in urban populations of children (n=2 510 and women (n=874 in the early postpartum in certain districts of Lima and Callao, and to correlate those levels with particular exposures. MATERIAL AND METHODS: Between July 1998 and January 1999 cross sectional study was conducted. The study population was selected using three sampling strategies in the government operated school system and from public pediatric and maternity hospitals at Lima and Callao, Peru. Study personnel were trained to collect finger stick blood samples with a protocol that minimizes external lead contamination. Lead determinations in blood and environmental samples were performed at the study site using portable anodic striping voltamenters. To determine the simultaneous effects of different predictors on blood lead levels, multivariate regression models were used to estimate adjusted mean differences. RESULTS: The mean blood lead level in the children studied was 9.9 µg/dl ranging from I µg/dl to 64 µg/dl with 29% of the children displaying values greater than 10 µg/dl and 9.4% at levels greater than 20 µg/dl. Among the women, the mean was 3.5 µg/dl (SD=2.4 µg/dl, and 2.4% (n=21 displayed levels greater than 10 µg/dl. Important differences were observed between the sample locations, and the highest levels were documented in the port region near Callao. The mean level of blood lead in this group was 25.6 µg/dl (SD=4.6 µg/dl, while among the rest of the sample it was 7.1 µg/dl (SD=5.1 µg/dl. The presence of a mineral storage area signified a difference in exposure in excess of 13 µg/dl for children living near the port area in contrast to the other children who were not as close to such fixed sources of lead exposure. For the participants in Lima, the risk of showing levels above 10 µg/dl was associated with exposure to high vehicular traffic. CONCLUSIONS: In metropolitan Lima, we conclude that the mean blood lead levels of

  16. Lead and PCB's in canvasback ducks: Relationship between enzyme levels and residues in blood

    Science.gov (United States)

    Dieter, M.P.; Perry, M.C.; Mulhern, B.M.

    1976-01-01

    Blood samples were taken for two successive years from canvasback ducks trapped in the Chesapeake Bay. The first winter (1972?1973) five plasma enzymes known to respond to organochlorine poisoning were examined. Abnormal enzyme elevations suggested that 20% of the population sampled (23/115 ducks) might contain organochlorine contaminants, but no residue analyses were performed. The second winter (1974) two of the same enzymes, aspartate aminotransferase and lactate dehydrogenase, and a third enzyme known to be specifically inhibited by lead, delta-aminolevulinic acid dehydratase, were assayed in 95 blood samples. Blood residues of organochlorine compounds and of lead were determined in representative samples, and the correlations between residue levels and enzyme changes were examined. The enzyme bioassays in 1974 indicated that lead was a more prevalent environmental contaminant than organochlorine compounds in canvasback ducks; 17% of the blood samples had less than one-half of the normal delta-aminolevulinic acid dehydratase activity, but only 11% exhibited abnormal aspartate aminotransferase or lactate dehydrogenase activities. These findings were confirmed by residue analyses that demonstrated lead concentrations four times higher than background levels, but only relatively low organochlorine concentrations. There was a highly significant inverse correlation between delta-aminolevulinic acid dehydratase activity and blood lead concentrations (Pcontamination in waterfowl. In canvasback ducks 200 ppb of lead in the blood caused a 75% decrease in delta-aminolevulinic acid dehydratase activity, a magnitude of enzyme inhibition that disturbs heme synthesis and is regarded as detrimental in humans.

  17. Concentrations of selenium, mercury, and lead in blood of emperor geese in western Alaska

    Science.gov (United States)

    Franson, J.C.; Schmutz, J.A.; Creekmore, L.H.; Fowler, A.C.

    1999-01-01

    We found up to 10 ppm wet weight of selenium in blood samples collected from emperor geese (Chen canagica) on their breeding grounds on the Yukon‐Kuskokwim Delta in western Alaska, USA. Incubating adult females captured in late May through mid‐June 1997 had significantly higher concentrations of selenium in their blood (mean = 5.60 ppm) than adult females captured during wing molt in late July 1996 (mean = 2.78 ppm). Females that nested early or were in good body condition had higher concentrations of selenium in their blood than did other nesting females. Blood samples from 4 of 29 goslings had detectable levels of selenium (mean = 0.14 ppm). Our findings suggest that emperor geese are exposed to more selenium in the marine environment of their wintering and staging areas on the Alaska Peninsula than on the breeding grounds. The highest concentration of mercury found in the blood of emperor geese was 0.24 ppm. One bird had a blood lead concentration of 0.67 ppm, but 82% had no detectable lead in their blood, suggesting that lead exposure from the ingestion of lead shot poses little threat for emperor geese in western Alaska, contrary to findings reported for sympatric spectacled eiders (Somateria fischeri).

  18. Determining lead concentration in the blood of primary school children in Damascus city and suburbs

    International Nuclear Information System (INIS)

    Al-Merey, R.; Al-Ghali, M.; Mortada, S.

    2006-01-01

    Due to the fact that lead is a relatively common element in nature and one of the most pollutant elements which man kind is exposed to in densely populated cities that have a large number of vehicles using leaded petrol which has bad effects on human health particularly children, it is found necessary to scan the health situation related to lead exposure in Damascus. The present work focuses on determining the concentration of lead in the blood of primary school children in Damascus city and some schools in the suburbs of Damascus. 546 blood samples were collected from school children in Damascus city and 183 blood samples from school children in the suburbs of Damascus. Parameters such as student's environmental, social and behavioral information were taken into consideration and correlate with lead concentration in students blood samples. Results showed that 76.3% of the samples have more than 10 μg/100 ml of lead in the blood. Which has lead to the following health effects: Decrease in hemoglobin and vitamin-D, Effects on central nervous system, Deterioration in children growth, decreasing in IQ, and kidney failure. (Authors)

  19. Determining lead concentration in the blood of primary school children in Damascus city and suburbs

    International Nuclear Information System (INIS)

    Al-Merey, R.; Galee, M.; Mortada, S.

    2005-05-01

    Due to the fact that lead is a relatively common element in nature and one of the most pollutant elements which man kind is exposed to in densely populated cities that have a large number of vehicles using leaded petrol which has bad effects on human health particularly children, it is found necessary to scan the health situation related to lead exposure in Damascus. The present work focuses on determining the concentration of lead in the blood of primary school children in Damascus city and some schools in the suburbs of Damascus. 546 blood samples were collected from school children in Damascus city and 183 blood samples from school children in the suburbs of Damascus. Parameters such as student's environmental, social and behavioral information were taken into consideration and correlate with lead concentration in students blood samples. Results showed that 76.3% of the samples have more than 10 μg/100 ml of lead in the blood. Which has lead to the following health effects: Decrease in hemoglobin and vitamin-D, Effects on central nervous system, Deterioration in children growth, decreasing in IQ, and kidney failure. (Authors)

  20. Non-linear development of secular gravitational instability in protoplanetary disks

    Science.gov (United States)

    Tominaga, Ryosuke T.; Inutsuka, Shu-ichiro; Takahashi, Sanemichi Z.

    2018-01-01

    We perform non-linear simulation of secular gravitational instability (GI) in protoplanetary disks, which has been proposed as a mechanism of planetesimal and multiple ring formation. Since the timescale of the growth of the secular GI is much longer than the Keplerian rotation period, we develop a new numerical scheme for a long-term calculation utilizing the concept of symplectic integration. With our new scheme, we first investigate the non-linear development of the secular GI in a disk without a pressure gradient in the initial state. We find that the surface density of dust increases by more than a factor of 100 while that of gas does not increase even by a factor of 2, which results in the formation of dust-dominated rings. A line mass of the dust ring tends to be very close to the critical line mass of a self-gravitating isothermal filament. Our results indicate that the non-linear growth of the secular GI provides a powerful mechanism to concentrate the dust. We also find that the dust ring formed via the non-linear growth of the secular GI migrates inward with a low velocity, which is driven by the self-gravity of the ring. We give a semi-analytical expression for the inward migration speed of the dusty ring.

  1. Secular change in 13 metabolic phenotypes: A Chinese longitudinal twin study

    DEFF Research Database (Denmark)

    Li, Shuxia; Pang, Zengchang; Zhang, Dongfeng

    in prospective investigations. Based on Chinese twin data collected from Danish-Chinese collaboration research, we perform twin modeling on 13 metabolic phenotypes (total cholesterol; triglyceride; high density lipoprotein (HDL); low density lipoprotein (LDL); urine acid (UA); glucose; weight; body mass index...... fitted to the secular changes in each of the 13 phenotypes with best fitting model selected based on model performance. Age and sex were included as covariates in the models to adjust for their effects on secular trend. Results: Variations in secular change in 3 lipids (total cholesterol; triglyceride...

  2. The Post-Secular Transformation of the Relation between Religion and Rationality

    Directory of Open Access Journals (Sweden)

    Carlos Miguel Gómez Rincón

    2015-04-01

    Full Text Available The article examines the idea of a direct link between modernization and the loss of plausibility of religious belief, explores the contemporary image of the relation between religion and rationality, and shows why it is not possible to say that the advance of science leads to secularization. In view of the question regarding whether postsecularization entails the mutual exclusion of religion and rationality, it examines the proposals of J. Habermas and N. Wolterstorff, in a search for normative criteria for the dialogue between religious and non-religious rationalities.

  3. The impact of a religious opera on a secular audience : The existential and religious importance of art

    NARCIS (Netherlands)

    Zock, T.H.; Alma, H.

    2005-01-01

    What role does art play in the life of contemporary, secularized people who are looking for existential and spiritual meaning? This was the leading question in our empirical research on the opera ‘‘Dialogues of the Carmelites’’ by the French composer, Francis Poulenc. First, we will sketch the

  4. Blood Lead Concentrations in Jamaican Children with and without Autism Spectrum Disorder

    Science.gov (United States)

    Rahbar, Mohammad H.; Samms-Vaughan, Maureen; Dickerson, Aisha S.; Loveland, Katherine A.; Ardjomand-Hessabi, Manouchehr; Bressler, Jan; Shakespeare-Pellington, Sydonnie; Grove, Megan L.; Pearson, Deborah A.; Boerwinkle, Eric

    2014-01-01

    Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder manifesting by early childhood. Lead is a toxic metal shown to cause neurodevelopmental disorders in children. Several studies have investigated the possible association between exposure to lead and ASD, but their findings are conflicting. Using data from 100 ASD cases (2–8 years of age) and their age- and sex-matched typically developing controls, we investigated the association between blood lead concentrations (BLC) and ASD in Jamaican children. We administered a questionnaire to assess demographic and socioeconomic information as well as exposure to potential lead sources. We used General Linear Models (GLM) to assess the association of BLC with ASD status as well as with sources of exposure to lead. In univariable GLM, we found a significant difference between geometric mean blood lead concentrations of ASD cases and controls (2.25 μg/dL cases vs. 2.73 μg/dL controls, p < 0.05). However, after controlling for potential confounders, there were no significant differences between adjusted geometric mean blood lead concentrations of ASD cases and controls (2.55 μg/dL vs. 2.72 μg/dL, p = 0.64). Our results do not support an association between BLC and ASD in Jamaican children. We have identified significant confounders when assessing an association between ASD and BLC. PMID:25546274

  5. Blood Lead Concentrations in Jamaican Children with and without Autism Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    Mohammad H. Rahbar

    2014-12-01

    Full Text Available Autism Spectrum Disorder (ASD is a neurodevelopmental disorder manifesting by early childhood. Lead is a toxic metal shown to cause neurodevelopmental disorders in children. Several studies have investigated the possible association between exposure to lead and ASD, but their findings are conflicting. Using data from 100 ASD cases (2–8 years of age and their age- and sex-matched typically developing controls, we investigated the association between blood lead concentrations (BLC and ASD in Jamaican children. We administered a questionnaire to assess demographic and socioeconomic information as well as exposure to potential lead sources. We used General Linear Models (GLM to assess the association of BLC with ASD status as well as with sources of exposure to lead. In univariable GLM, we found a significant difference between geometric mean blood lead concentrations of ASD cases and controls (2.25 μg/dL cases vs. 2.73 μg/dL controls, p < 0.05. However, after controlling for potential confounders, there were no significant differences between adjusted geometric mean blood lead concentrations of ASD cases and controls (2.55 μg/dL vs. 2.72 μg/dL, p = 0.64. Our results do not support an association between BLC and ASD in Jamaican children. We have identified significant confounders when assessing an association between ASD and BLC.

  6. Regular Breakfast and Blood Lead Levels among Preschool Children

    Directory of Open Access Journals (Sweden)

    Needleman Herbert

    2011-04-01

    Full Text Available Abstract Background Previous studies have shown that fasting increases lead absorption in the gastrointestinal tract of adults. Regular meals/snacks are recommended as a nutritional intervention for lead poisoning in children, but epidemiological evidence of links between fasting and blood lead levels (B-Pb is rare. The purpose of this study was to examine the association between eating a regular breakfast and B-Pb among children using data from the China Jintan Child Cohort Study. Methods Parents completed a questionnaire regarding children's breakfast-eating habit (regular or not, demographics, and food frequency. Whole blood samples were collected from 1,344 children for the measurements of B-Pb and micronutrients (iron, copper, zinc, calcium, and magnesium. B-Pb and other measures were compared between children with and without regular breakfast. Linear regression modeling was used to evaluate the association between regular breakfast and log-transformed B-Pb. The association between regular breakfast and risk of lead poisoning (B-Pb≥10 μg/dL was examined using logistic regression modeling. Results Median B-Pb among children who ate breakfast regularly and those who did not eat breakfast regularly were 6.1 μg/dL and 7.2 μg/dL, respectively. Eating breakfast was also associated with greater zinc blood levels. Adjusting for other relevant factors, the linear regression model revealed that eating breakfast regularly was significantly associated with lower B-Pb (beta = -0.10 units of log-transformed B-Pb compared with children who did not eat breakfast regularly, p = 0.02. Conclusion The present study provides some initial human data supporting the notion that eating a regular breakfast might reduce B-Pb in young children. To our knowledge, this is the first human study exploring the association between breakfast frequency and B-Pb in young children.

  7. Individual and environmental risk factors for high blood lead concentrations in Danish indoor shooters

    DEFF Research Database (Denmark)

    Grandahl, Kasper; Suadicani, Poul; Jacobsen, Peter

    2012-01-01

    International studies have shown blood lead at levels causing health concern in recreational indoor shooters. We hypothesized that Danish recreational indoor shooters would also have a high level of blood lead, and that this could be explained by shooting characteristics and the physical...

  8. Lead contents in blood samples of a children population of Mexico City related to levels of airborne lead determined by PIXE

    International Nuclear Information System (INIS)

    Uribe-Hernandez, R.; Perez-Zapata, A.J.; Flores M., J.; Aldape, F.; Hernandez-Mendez, B.

    1996-01-01

    Airborne lead has been considered for many years one of the main pollutants adversely affecting the health of human beings. Moreover, this problem becomes remarkably important in large urban areas such as Mexico City. In order to assess the influence of atmospheric airborne lead in a children population, a biological blood sampling was carried out from September 1992 to June 1993 taking 698 samples in children with ages ranging from a few weeks to thirteen years old. Lead contents in whole blood were determined using anode stripping voltammetry as analytical technique. At the same time, aerosol lead contents were determined by PIXE from samples taken twice a week (two samples per day) in a neighbour area. In 58% of the samples, lead contents in blood was found over the maximum permissible level established by the Center for Disease Control (CDC) of the U.S.A. The biological sampling was correlated to levels of airborne lead as well as children age and date of sampling. General results of these comparisons are presented. (author)

  9. Secular stability of rotating stars

    International Nuclear Information System (INIS)

    Imamura, J.N.; Friedman, J.L.; Durisen, R.H.

    1984-01-01

    In this work, the authors calculate the secular stability limits of rotating polytropes to nonaxisymmetric perturbations of low m. Polytropic indices ranging from 1 to 3 and several angular momentum distributions are considered. Results are most conveniently presented in terms of the t-parameter, defined as the ratio of the rotational kinetic energy to the absolute value of the gravitational energy of the fluid. Previous work on polytropes considered only the m = 2 mode, which is unstable for values of the t-parameter greater than 0.14 +- 0.01 for the n values n = 1.5 and 3 and the angular momentum distributions tested (see Durisen and Imamura 1981). The GRR secular stability limit of the m - 2 mode for the Maclaurin spheroids (n = 0) was determined by Chandrasekhar (1970). GRR stability limits of higher m modes for the Maclaurin spheroids were located approximately by Comins (1979a,b) and more precisely by Friedman (1983). 16 references, 2 tables

  10. Secular stability of rotating stars

    International Nuclear Information System (INIS)

    Imamura, J.N.; Friedman, J.L.; Durisen, R.H.

    1984-01-01

    In this work, we calculate the secular stability limits of rotating polytropes to nonaxisymmetric perturbations of low m. We consider polytropic indices ranging from 1 to 3 and several angular momentum distributions. Results are most conveniently presented in terms of the t-parameter, defined as the ratio of the rotational kinetic energy to the absolute value of the gravitational energy of the fluid. Previous work on polytropes considered only the m = 2 mode, which is unstable for values of the t-parameter greater than 0.14 +- 0.01 for the n values n = 1.5 and 3 and the angular momentum distributions tested (see Durisen and Imamura 1981). The GRR secular stability limit of the m = 2 mode for the Maclaurin spheroids (n = O) was determined by Chandrasekhar (1970). GRR stability limits of higher m modes for the Maclaurin spheroids were located approximately by Comins (1979a,b) and more precisely by Friedman (1983)

  11. Daily rhythms in blood and milk lead toxicokinetics following intravenous administration of lead acetate to dairy cows in summer

    Science.gov (United States)

    Valtorta, S. E.; Scaglione, M. C.; Acosta, P.; Coronel, J. E.; Beldomenico, H. R.; Boggio, J. C.

    2006-01-01

    The objective of this study was to investigate circadian variations of blood and milk lead toxicokinetics in dairy cows in summer. Twenty lactating Holstein animals were randomly assigned to four treatments corresponding to different hours after onset of light (HALO): 2, 8, 14, and 20. Cows received a single intravenous administration of 2.5 mg/kg lead as lead acetate. Blood and milk samples were taken and analyzed by atomic absorption spectrophotometry. For each toxicokinetic parameter, a one-way analysis of variance (ANOVA) was performed to outline the existence of daily variations. Significant blood differences as a function of HALO were found for the hybrid constant of distribution (α), hybrid constant of elimination (β), elimination half-life ({text{t}}_{{{text{1/2 β }}}} ), area under the curve (AUC), volume of distribution at steady state (Vss) and clearance (ClB) ( pMilk data showed significant differences for maximum concentration and AUC ( pmilk. It differed significantly throughout the day ( pMilk data for the significant parameters could be fitted to circadian rhythms. No circadian rhythms were detected in blood parameters or in the ratio AUCmilk/AUCblood.

  12. Contemporary environmentalism as a current of spiritual post-secular practice

    Directory of Open Access Journals (Sweden)

    Laura Wickström

    2012-01-01

    Full Text Available Contemporary spirituality often bears the stamp of an eco-discourse. It is characteristic of post-spiritual practices that there is a blurring of the boundaries between the sacred and profane and in this sphere, influenced by the eco-consciousness, nature and the body can be sacralised. In this article the author looks into environmentalism as a current in spirituality. First spirituality as a concept is discussed. Second follows a section on aspects of contemporary environmentalism, dealing with new social movements, new identity and the main directions of environmentalism. After that, the distinction between environmentally motivated spirituality and spir­itually motivated environmentalism is presented. At the end there is a short discussion of post-secular issues concerning environmentalism. Worldviews are no longer necessarily either religious or secular, but may also combine elements of rational secularity with enchanted spirituality. The blurring of the boundaries between secular and religious views and motives occur, as well as the separation of mind and body, rationality and belief, and human and nature.

  13. Blood Lead Levels and Risk Factors for Lead Exposure in a Pediatric Population in Ho Chi Minh City, Vietnam

    Directory of Open Access Journals (Sweden)

    Deborah Havens

    2018-01-01

    Full Text Available Although lead recycling activities are a known risk factor for elevated blood levels in South East Asia, little is known regarding the prevalence of and risk factors for elevated blood lead levels (BLL among the general pediatric population in Vietnam. This study is a cross-sectional evaluation of 311 children from Children’s Hospital #2 in Ho Chi Minh City, Vietnam. Capillary blood lead testing was performed using the LeadCare II. Mean BLLs were 4.97 μg/dL (Standard Deviation (SD 5.50, with 7% of the participants having levels greater than 10 μg/dL. Living in Bing Duong province (OR 2.7, 95% CI 1.4–5.6.1 or the Dong Nai province (OR 2.3, 95% CI 1.0–5.1 and having an age greater than 12 months (OR 6.0, 95% CI 3.1–11.8 were associated with higher BLLs. The prevalence of elevated BLLs in Vietnam is consistent with other SE Asian countries. Mean BLLs in Ho Chi Minh City are markedly less than those seen in a separate study of children living near lead recycling activities. Additional evaluation is necessary to better detail potential risk factors if screening is to be implemented within Vietnam.

  14. Blood lead level and its relationship to essential elements in preschool children from Nanning, China.

    Science.gov (United States)

    Chen, Jingwen; Li, Muyan; Lv, Qun; Chen, Guoli; Li, Yong; Li, Shaojun; Mo, Yuhuan; Ou, Shiyan; Yuan, Zongxiang; Huang, Mingli; Jiang, Yueming

    2015-04-01

    Our study aimed to assess the distribution of blood lead level and its relationship to essential elements in preschool children in an urban area of China. A total of 6741 children aged 0- to 6-year-old were recruited. Levels of lead, zinc, copper, iron, calcium, and magnesium in whole blood samples were determined using atomic absorption spectrometry. The mean blood lead level (BLL) and the prevalence of BLL≥10μg/dl (5.26±4.08μg/dl and 6.84%, respectively) increased with age gradually, and there was a gender-difference for blood lead, copper, zinc and iron levels. Compared with the group of children who had BLLslead with zinc, iron and magnesium, and a negative correlation of lead with calcium were found in the group of children with BLLintoxication prevalence in preschool children. Metabolic disorder of essential elements was found even with a low level of lead exposure. Copyright © 2014 Elsevier GmbH. All rights reserved.

  15. A comparison of the diminution rates of lead in blood and lead mobilized by CaEDTA after termination of occupational exposure: a long-term observation in two lead workers.

    Science.gov (United States)

    Araki, S; Murata, K; Aono, H; Yanagihara, S; Ushio, K

    1983-07-01

    CaEDTA 20 mg/kg was administered weekly for 3.5 years after termination of occupational exposure to two lead workers. The diminution half-lives for lead in blood and urine lead mobilized by CaEDTA were 4.8 and 3.3 years respectively for subject 1 following 28 years exposure and 3.3 and 2.0 years respectively for subject 2 following 26 years exposure. The difference in the diminution rate between lead in blood and lead mobilized by CaEDTA was significant in subject 2 (p less than 0.05).

  16. Familial resemblance in religiousness in a secular society

    DEFF Research Database (Denmark)

    Hvidtjørn, Dorte; Petersen, Inge; Hjelmborg, Jacob

    2013-01-01

    generally considered more religious than the very secular northern European countries. Comparisons of the results are complicated by diverse definitions of religiousness, but several studies indicate that the influence of the family environment is most predominant in early life, whereas genetic influences...... increase with age. We performed a population-based twin study of religiousness in a secular society using data from a Web-based survey sent to 6,707 Danish twins born 1970-1989, who were identified in the Danish Twin Registry. We applied Fishman's three conceptual dimensions of religiousness: cognition...

  17. A polymorphism in AGT and AGTR1 gene is associated with lead-related high blood pressure.

    Science.gov (United States)

    Kim, Hyung-Ki; Lee, Hwayoung; Kwon, Jun-Tack; Kim, Hak-Jae

    2015-12-01

    We investigated the association of polymorphisms in two renin-angiotensin system-related genes, expressed as angiotensinogen (AGT) and angiotensin II type 1 receptor (AGTR1), with blood lead levels and lead-related blood pressure in lead-exposed male workers in Korea. A cross-sectional study involving 808 lead-exposed male workers in Korea was conducted using a restriction fragment length polymorphism-based strategy to differentiate the various genotypes of polymorphisms in the AGT and AGTR1 genes. The association of clinical characteristics with genotypes as modifiers was estimated after adjustment for age, smoking status, drinking status, body mass index and job duration of each subject. Genotype and allele frequencies of the M235T polymorphism in AGT were associated with lead-related high blood pressure status. Moreover, blood lead levels were associated with allele frequencies of the AGT M235T polymorphism. These results suggested that the M/M genotype and M allele of AGT are risk factors for lead-related high blood pressure. © The Author(s) 2014.

  18. Post-religional perspective and secular Buddhism: Stephen Batchelor and the post-metaphysical religion

    Directory of Open Access Journals (Sweden)

    Leandro Durazzo

    2015-04-01

    Full Text Available This paper aims to present one of the contemporary trends on Buddhism, specially from the last decades in West, for its encounter with the globalized and dynamic context of present societies. This Buddhist trend, the progressive secularization of its traditions and practices, not to mention its increasing acceptance of historical-textual refutation, finds in Stephen Batchelor - a former monk in two different Buddhist traditions, Tibetan and Korean Zen - a catalyzer and a well-known advocate of secular perspective to the contemporary Buddhism. Here we will present the potential dialogue between the Secular Buddhism - besides the secularizing perspectives over orthodox cultural traditions - and the post-religional subject, as proposed by Marià Corbí and the Ecumenical Association of Third World Theologians. For the purposes of this paper we will focus on the modernizing and secular hermeneutics on Dharma practice, as defended by Stephen Batchelor and others.

  19. Technical Limitations in Merging Secular and Sacred Functions in Monumental Churches

    Science.gov (United States)

    Piatkowska, Ksenia

    2017-10-01

    The abandonment of churches and their adaptation for secular purposes is a current subject in Europe and worldwide. Most cases involve objects that were desacralized and then rebuilt as a whole object for alternative functions. Thus far, the merging of secular and sacred functions in one monumental Catholic church has not raised any issues. The paper describes the case of St. Catherine’s Church in Gdansk, Poland, where sacred function exists parallel to the new secular function being implemented. The study is based on the authentic, professional experience of the author. It describes the technical limitations arising from the need to ensure destinies for the optimal conditions of both sacred and secular function, while avoiding undesirable interference between them. The author further identifies architectural solutions most relevant to current requirements for protection of sacred zones in the church, for preservation of the monument, and for optimal function of a modern science museum. Significant design issues include: the inviolability of the sacred zone, preservation of the historical value of the monument, proper operation of new secular zones in compliance with contemporary standards of safety, performance of the assumed mission and profitability. The research indicates specific areas where the highest probability of collision exists between the sacred and profane and where technical problems are likely to occur.

  20. Secular changes in Earth's shape and surface mass loading derived from combinations of reprocessed global GPS networks

    Science.gov (United States)

    Booker, David; Clarke, Peter J.; Lavallée, David A.

    2014-09-01

    The changing distribution of surface mass (oceans, atmospheric pressure, continental water storage, groundwater, lakes, snow and ice) causes detectable changes in the shape of the solid Earth, on time scales ranging from hours to millennia. Transient changes in the Earth's shape can, regardless of cause, be readily separated from steady secular variation in surface mass loading, but other secular changes due to plate tectonics and glacial isostatic adjustment (GIA) cannot. We estimate secular station velocities from almost 11 years of high quality combined GPS position solutions (GPS weeks 1,000-1,570) submitted as part of the first international global navigation satellite system service reprocessing campaign. Individual station velocities are estimated as a linear fit, paying careful attention to outliers and offsets. We remove a suite of a priori GIA models, each with an associated set of plate tectonic Euler vectors estimated by us; the latter are shown to be insensitive to the a priori GIA model. From the coordinate time series residuals after removing the GIA models and corresponding plate tectonic velocities, we use mass-conserving continental basis functions to estimate surface mass loading including the secular term. The different GIA models lead to significant differences in the estimates of loading in selected regions. Although our loading estimates are broadly comparable with independent estimates from other satellite missions, their range highlights the need for better, more robust GIA models that incorporate 3D Earth structure and accurately represent 3D surface displacements.

  1. Cognitive dissonance between religious and secular social attitudes

    Directory of Open Access Journals (Sweden)

    Marković Jelena

    2003-01-01

    Full Text Available The initial finding of the study, which served as the basis for the exploration of cognitive dissonance between religious and secular behavioral norms, was revealed in a tendency of the majority of religious students to accept behavioral norms, attitudes and believes (concerning interpersonal relationships and reproduction-related ethical issues which are not supported by Orthodox Christian Church viewpoint and teachings. However, certain cognitive and value system consistency appeared to exist: the intensity of religiousness was related to lower degrees of secular norms approval. It has been found that religious and nonreligious subjects differ significantly in their preference of the strategy used to maintain balance between dissonant religious and secular attitudes- in 3 out of 4 issues considered in the study. Religious subjects most frequently chose relativism strategy, claiming that some specific exceptions from a general rule or standpoint do not necessarily depreciate it, while nonreligious subjects most frequently chose dualistic viewpoint that principally separated and restricted domains of reasoning on spiritual and worldly issues, making them psychologically irrelevant to one another.

  2. Secular Examination of Spirituality-Prosociality Association

    NARCIS (Netherlands)

    Dong, Mengchen; Wu, Song; Zhu, Yijie; Jin, Shenghua; Zhang, Yanjun

    2017-01-01

    Religious beliefs in Chinese cultural background, especially in Chinese secular society, have rarely been systematically investigated. The nonreligious-based population in China endorses certain supernatural beliefs or has related transcendent experience, even though they usually claim themselves as

  3. Blood lead concentrations as a result of retained lead pellets in the craniomaxillofacial region in Benin City, Nigeria.

    Science.gov (United States)

    Edetanlen, B E; Saheeb, B D

    2016-06-01

    Patients who survive gunshot wounds often retain pellets in their bodies, which cause delayed morbidity from lead poisoning, and even death. Our aim was to find out whether there is a high concentration of lead in the blood of patients who have asymptomatic retention of lead pellets in the craniomaxillofacial region. We prospectively studied 28 patients who were admitted to our hospital with gunshot injuries to the region, and 28 control subjects. Each was originally recruited three days after injury. The control subjects were chosen from people who lived in the same household or worked in the same place as the patients. Any previous exposure to lead was excluded. Blood samples were collected three days and three months after injury and analysed for the presence of lead by atomic absorption spectrophotometry. The mean (SD) age for both patients and control subjects was 33 (12) years. The mean (SD) and range of concentrations of lead in patients three days after injury was 0.11 (0.07), range 0.01-0.32μmol/L, while those of the control subjects were 0.03 (0.02) and 0-0.06, respectively. Three months after injury, the mean (SD) and range of concentrations of the patients were 0.30 (0.11) and 0.12-0.59μmol/L, while those of the control subjects were 0-1.25 and 0.12 (0.006) μmol/L, respectively (p= 0.000). The study showed a higher mean blood lead concentration in patients with gunshot injuries than in control subjects, but lower than the threshold values published by the Centers for Disease Control/Occupational Health and Safety Administration in the United States. Copyright © 2016 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  4. Questioning Engelhardt's assumptions in Bioethics and Secular Humanism.

    Science.gov (United States)

    Ahmadi Nasab Emran, Shahram

    2016-06-01

    In Bioethics and Secular Humanism: The Search for a Common Morality, Tristram Engelhardt examines various possibilities of finding common ground for moral discourse among people from different traditions and concludes their futility. In this paper I will argue that many of the assumptions on which Engelhardt bases his conclusion about the impossibility of a content-full secular bioethics are problematic. By starting with the notion of moral strangers, there is no possibility, by definition, for a content-full moral discourse among moral strangers. It means that there is circularity in starting the inquiry with a definition of moral strangers, which implies that they do not share enough moral background or commitment to an authority to allow for reaching a moral agreement, and concluding that content-full morality is impossible among moral strangers. I argue that assuming traditions as solid and immutable structures that insulate people across their boundaries is problematic. Another questionable assumption in Engelhardt's work is the idea that religious and philosophical traditions provide content-full moralities. As the cardinal assumption in Engelhardt's review of the various alternatives for a content-full moral discourse among moral strangers, I analyze his foundationalist account of moral reasoning and knowledge and indicate the possibility of other ways of moral knowledge, besides the foundationalist one. Then, I examine Engelhardt's view concerning the futility of attempts at justifying a content-full secular bioethics, and indicate how the assumptions have shaped Engelhardt's critique of the alternatives for the possibility of content-full secular bioethics.

  5. Loners, Groupies, and Long-term Eccentricity (and Inclination) Behavior: Insights from Secular Theory

    Science.gov (United States)

    Van Laerhoven, Christa L.

    2015-05-01

    Considering the secular dynamics of multi-planet systems provides substantial insight into the interactions between planets in those systems. Secular interactions are those that don't involve knowing where a planet is along its orbit, and they dominate when planets are not involved in mean motion resonances. These interactions exchange angular momentum among the planets, evolving their eccentricities and inclinations. To second order in the planets' eccentricities and inclinations, the eccentricity and inclination perturbations are decoupled. Given the right variable choice, the relevant differential equations are linear and thus the eccentricity and inclination behaviors can be described as a sum of eigenmodes. Since the underlying structure of the secular eigenmodes can be calculated using only the planets' masses and semi-major axes, one can elucidate the eccentricity and inclination behavior of planets in exoplanet systems even without knowing the planets' current eccentricities and inclinations. I have calculated both the eccentricity and inclination secular eigenmodes for the population of known multi-planet systems whose planets have well determined masses and periods. Using this catalog of secular character, I will discuss the prevalence of dynamically grouped planets ('groupies') versus dynamically uncoupled planets ('loners') and how this relates to the exoplanets' long-term eccentricity and inclination behavior. I will also touch on the distribution of the secular eigenfreqiencies.

  6. Substitution or Symbiosis? Assessing the Relationship between Religious and Secular Giving

    Science.gov (United States)

    Hill, Jonathan P.; Vaidyanathan, Brandon

    2011-01-01

    Research on philanthropy has not sufficiently examined whether charitable giving to religious causes impinges on giving to secular causes. Examining three waves of national panel data, we find that the relationship between religious and secular giving is generally not of a zero-sum nature; families that increase their religious giving also…

  7. Seasonality and trend in blood lead levels of New York State children

    Directory of Open Access Journals (Sweden)

    Talbot Thomas O

    2004-06-01

    Full Text Available Abstract Background Environmental exposure to lead remains a significant health problem for children. The costs of lead exposure in children are estimated to be considerably more than other childhood diseases of environmental origin. While long-term trends in blood lead levels (BLLs among children are declining, seasonal variation persists. Cross-sectional studies have found a peak in summer months. Part of this variation may be due to increased exposure to lead paint on window sills and through increased contact with soils containing lead during the summer. The current study represents the largest published population-based study on seasonality and trends in the BLLs of children to date. In addition, the results offer a comparison of recent data on seasonality of BLLs in New York State children, to studies conducted over the past three decades. Methods 262,687 New York State children born between 1994 and 1997 were screened for blood lead within 2 weeks of their first or second birthdays. Time series analyses of blood lead data from these children were conducted to study the seasonality and trends of BLLs. Results Children's blood lead values showed a distinct seasonal cycle on top of a long-term decreasing trend. The geometric mean BLL declined by about 24% for children born between 1994 and 1997. The prevalence of elevated BLLs in two-year-olds was almost twice that in one-year-olds over the time period. Nearly twice as many children had elevated BLLs in the late summer compared to late winter/early spring. In this and previous cross-sectional studies, the amount of seasonality as a proportion of the mean ranged between 15% and 30%. Conclusion Pediatricians should be aware of the seasonality of BLLs. For example, if a two-year-old receives a borderline result during the winter, it is possible that the levels would have been higher if he had been tested during the summer. However, physicians should continue to screen children at their normally

  8. Comparative Assessment of Blood Lead Levels of Automobile Technicians in Organised and Roadside Garages in Lagos, Nigeria

    Directory of Open Access Journals (Sweden)

    Abdulsalam Saliu

    2015-01-01

    Full Text Available Occupational exposure to lead is common among automobile technicians and constitutes 0.9% of total global health burden with a majority of cases in developing countries. The aim of this study was to determine and compare the blood lead levels of automobile technicians in roadside and organised garages in Lagos State, Nigeria. This was a comparative cross-sectional study. Data were collected using interviewer-administered questionnaires. Physical examinations were conducted and blood was analysed for lead using atomic spectrophotometery. Statistical analyses were performed to compare the median blood lead levels of each group using the independent sample (Mann-Whitney U test. Seventy-three (40.3% of the organised compared to 59 (34.3% of the roadside groups had high blood lead levels. The organised group had statistically significant higher median blood lead levels of, 66.0 µg/dL than the roadside 43.5 µg/dL (P < 0.05. There was also statistically significant association between high blood lead levels and abnormal discolouration of the mucosa of the mouth in the organised group. Automobile technicians in organised garages in Lagos have higher prevalence of elevated blood lead levels and higher median levels than the roadside group. Preventive strategies against lead exposures should be instituted by the employers and further actions should be taken to minimize exposures, improve work practices, implement engineering controls (e.g., proper ventilation, and ensure the use of personal protective equipment.

  9. SECULAR EVOLUTION OF BINARIES NEAR MASSIVE BLACK HOLES: FORMATION OF COMPACT BINARIES, MERGER/COLLISION PRODUCTS AND G2-LIKE OBJECTS

    International Nuclear Information System (INIS)

    Prodan, Snezana; Antonini, Fabio; Perets, Hagai B.

    2015-01-01

    Here we discuss the evolution of binaries around massive black holes (MBHs) in nuclear stellar clusters. We focus on their secular evolution due to the perturbation by the MBHs, while simplistically accounting for their collisional evolution. Binaries with highly inclined orbits with respect to their orbits around MBHs are strongly affected by secular processes, which periodically change their eccentricities and inclinations (e.g., Kozai-Lidov cycles). During periapsis approach, dissipative processes such as tidal friction may become highly efficient, and may lead to shrinkage of a binary orbit and even to its merger. Binaries in this environment can therefore significantly change their orbital evolution due to the MBH third-body perturbative effects. Such orbital evolution may impinge on their later stellar evolution. Here we follow the secular dynamics of such binaries and its coupling to tidal evolution, as well as the stellar evolution of such binaries on longer timescales. We find that stellar binaries in the central parts of nuclear stellar clusters (NSCs) are highly likely to evolve into eccentric and/or short-period binaries, and become strongly interacting binaries either on the main sequence (at which point they may even merge), or through their later binary stellar evolution. The central parts of NSCs therefore catalyze the formation and evolution of strongly interacting binaries, and lead to the enhanced formation of blue stragglers, X-ray binaries, gravitational wave sources, and possible supernova progenitors. Induced mergers/collisions may also lead to the formation of G2-like cloud-like objects such as the one recently observed in the Galactic center

  10. Resurrecting Democracies : Secularity Recast in Charles Taylor, Paul Valadier, and Joseph Ratzinger

    NARCIS (Netherlands)

    Ossewaarde-Lowtoo, Roshnee

    In this article, the alternative conception of secularity of Charles Taylor, Paul Valadier and Joseph Ratzinger (former Benedict XVI) is explored. A secularized society, which they take as an established condition, does not necessarily exclude religion, Christianity or Christian transcendence, in

  11. The effect of illegal lead processing on blood lead levels in children living in the mining area

    Directory of Open Access Journals (Sweden)

    Ćorac Aleksandar

    2017-01-01

    Full Text Available Backgraund/Aim. The northern part of Kosovo was one of the largest lead and zinc production industries in Europe. Special attention has been paid to the landfill sites of these metals remained after past industrial activities. The inhabitants of Roma camps in this area are collecting led waste they process by crushing and melting in their shacks in primitively organized working environments. Because of all the aforementioned it was necessary to examine the concentration of blood lead level (BLL in the children aged less than 6 years inhabiting this area, especially taking care of blood analysis of children living in Roma camps. Methods. The study was conducted in the municipality of Leposavić, Province Kosovo and Metohija, Serbia. Totally 78 subjects participated in the study. All the subjects were divided into two groups: the group I consisting of 42 children who lived in the Romas camp, and the group II with 36 children from a city kindergarten. Based on the mathematical model WRPLOT we found out that both groups of patients were in the low risk zone for industrial contamination exposure. Blood analysis was done according to the protocol provided by ESA Lead Care. Results. The average age of participants in the study was 4.60 ± 1.63 years. The mean BBL in the children from the group 1 was 19.11 μg/dL and from the group 2 4.87 μg/dL. There was a statistically significant difference in the mean values of BBL between the groups (U = 39, p < 0.001. All of the children from the group 1 had BBL greater than 5 μg/dL in comparison to 38.9% of the children from the group 2 (χ2 = 35.75, p < 0.001. Conclusion. Although both groups were located outside the zone of direct spread of pollution, the results indicate high concentrations of lead in blood of all the examined children. The concentration was higher in the children who lived in the area in which illegal processing of lead waste took place. [Project of the Serbian Ministry of Education

  12. Concentrations of heavy metals (lead, manganese, cadmium) in blood and urine of former uranium workers

    International Nuclear Information System (INIS)

    Apostolova, D.; Pavlova, S.; Paskalev, Z.

    1999-01-01

    Uranium ores contain heavy metals and other stable chemical elements as oxides, hydro-carbonates, sulphates, etc. During chemical processing of ore they could be transformed into compounds soluble in biologic liquids. The purpose of this study was to determine the combined intoxication of uranium miners and millers by heavy metals and radiation. Heavy metal (lead, manganese and cadmium) concentrations in blood and urine od 149 former uranium miners and millers were determined by AAS method. Data of significantly increased lead and manganese concentration in blood (p<0.05) of two groups were established in comparison with a control group. There is no statistical significant differences in the cadmium concentrations. The lead and manganese blood levels at the uranium millers were significant higher than those of the uranium miner group (p<0.05). Tendency towards increased blood lead concentrations of uranium millers depending on the length of service was established

  13. Blood lead levels, iron metabolism gene polymorphisms and homocysteine: a gene-environment interaction study.

    Science.gov (United States)

    Kim, Kyoung-Nam; Lee, Mee-Ri; Lim, Youn-Hee; Hong, Yun-Chul

    2017-12-01

    Homocysteine has been causally associated with various adverse health outcomes. Evidence supporting the relationship between lead and homocysteine levels has been accumulating, but most prior studies have not focused on the interaction with genetic polymorphisms. From a community-based prospective cohort, we analysed 386 participants (aged 41-71 years) with information regarding blood lead and plasma homocysteine levels. Blood lead levels were measured between 2001 and 2003, and plasma homocysteine levels were measured in 2007. Interactions of lead levels with 42 genotyped single-nucleotide polymorphisms (SNPs) in five genes ( TF , HFE , CBS , BHMT and MTR ) were assessed via a 2-degree of freedom (df) joint test and a 1-df interaction test. In secondary analyses using imputation, we further assessed 58 imputed SNPs in the TF and MTHFR genes. Blood lead concentrations were positively associated with plasma homocysteine levels (p=0.0276). Six SNPs in the TF and MTR genes were screened using the 2-df joint test, and among them, three SNPs in the TF gene showed interactions with lead with respect to homocysteine levels through the 1-df interaction test (plead levels. Blood lead levels were positively associated with plasma homocysteine levels measured 4-6 years later, and three SNPs in the TF gene modified the association. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  14. Blood lead levels in children, China

    International Nuclear Information System (INIS)

    Wang Shunqin; Zhang Jinliang

    2006-01-01

    To evaluate Chinese children's blood lead levels (BLLs) and identify its distribution features, we collected articles on children's BLLs published from 1994 to March 2004 using the Chinese Biomedical Disc and reviewed 32 articles eligible for the following criteria: (1) BLLs measured by Graphite Furnace Atomic Absorption Spectroscopy or Inductively Coupled Plasma-Mass Spectrometry; (2) strict quality control; (3) no lead pollution sources in the areas where the screened subjects live; and (4) sample size bigger than 100. We found that mean BLLs of Chinese children was 92.9 μg/L (37.2-254.2 μg/L), and 33.8% (9.6-80.5%) of the subjects had BLLs higher than 100 μg/L. Nine of the 27 provinces or cities reported had average BLLs ≥100 μg/L. Boys' BLL was 96.4 μg/L, significantly higher than girls' 89.4 μg/L (P<0.001). BLLs of children ≤6 years increased with age. The mean BLLs of children living in industrial and urban areas were significantly higher than those of children in suburbs and rural areas. Our results suggested that children's BLLs in China are higher than those of their counterparts in other countries due to its heavy lead pollution. Therefore, this is of great public health importance

  15. One Size Does Not Fit All: Complexity, Religion, Secularism and Education

    Science.gov (United States)

    Davies, Lynn

    2014-01-01

    The continuing incidence of extremist acts committed in the name of religion underscores the need to examine the interplay between religion and learning. This article argues for a secular foundation in society and school to protect against religion contributing to conflict and extremism. However, this is not a hard version of secularism, but a…

  16. An assessment of contemporary atomic spectroscopic techniques for the determination of lead in blood and urine matrices

    Science.gov (United States)

    Parsons, Patrick J.; Geraghty, Ciaran; Verostek, Mary Frances

    2001-09-01

    The preparation and validation of a number of clinical reference materials for the determination of lead in blood and urine is described. Four candidate blood lead reference materials (Lots, 047-050), and four candidate urine lead reference materials (Lots, 034, 035, 037 and 038), containing physiologically-bound lead at clinically relevant concentrations, were circulated to up to 21 selected laboratories specializing in this analysis. Results from two interlaboratory studies were used to establish certified values and uncertainty estimates for these reference materials. These data also provided an assessment of current laboratory techniques for the measurement of lead in blood and urine. For the blood lead measurements, four laboratories used electrothermal atomization AAS, three used anodic stripping voltammetry and one used both ETAAS and ICP-MS. For the urine lead measurements, 11 laboratories used ETAAS (most with Zeeman background correction) and 10 used ICP-MS. Certified blood lead concentrations, ±S.D., ranged from 5.9±0.4 μg/dl (0.28±0.02 μmol/l) to 76.0±2.2 μg/dl (3.67±0.11 μmol/l) and urine lead concentrations ranged from 98±5 μg/l (0.47±0.02 μmol/l) to 641±36 μg/l (3.09±0.17 μmol/l). The highest concentration blood lead material was subjected to multiple analyses using ETAAS over an extended time period. The data indicate that more stringent internal quality control practices are necessary to improve long-term precision. While the certification of blood lead materials was accomplished in a manner consistent with established practices, the urine lead materials proved more troublesome, particularly at concentrations above 600 μg/l (2.90 μmol/l).

  17. SECULAR EVOLUTION OF COMPACT BINARIES NEAR MASSIVE BLACK HOLES: GRAVITATIONAL WAVE SOURCES AND OTHER EXOTICA

    International Nuclear Information System (INIS)

    Antonini, Fabio; Perets, Hagai B.

    2012-01-01

    The environment near supermassive black holes (SMBHs) in galactic nuclei contains a large number of stars and compact objects. A fraction of these are likely to be members of binaries. Here we discuss the binary population of stellar black holes and neutron stars near SMBHs and focus on the secular evolution of such binaries, due to the perturbation by the SMBH. Binaries with highly inclined orbits with respect to their orbit around the SMBH are strongly affected by secular Kozai processes, which periodically change their eccentricities and inclinations (Kozai cycles). During periapsis approach, at the highest eccentricities during the Kozai cycles, gravitational wave (GW) emission becomes highly efficient. Some binaries in this environment can inspiral and coalesce at timescales much shorter than a Hubble time and much shorter than similar binaries that do not reside near an SMBH. The close environment of SMBHs could therefore serve as a catalyst for the inspiral and coalescence of binaries and strongly affect their orbital properties. Such compact binaries would be detectable as GW sources by the next generation of GW detectors (e.g., advanced-LIGO). Our analysis shows that ∼0.5% of such nuclear merging binaries will enter the LIGO observational window while on orbits that are still very eccentric (e ∼> 0.5). The efficient GW analysis for such systems would therefore require the use of eccentric templates. We also find that binaries very close to the SMBH could evolve through a complex dynamical (non-secular) evolution, leading to emission of several GW pulses during only a few years (though these are likely to be rare). Finally, we note that the formation of close stellar binaries, X-ray binaries, and their merger products could be induced by similar secular processes, combined with tidal friction rather than GW emission as in the case of compact object binaries.

  18. Institutional Confidence in the United States: Attitudes of Secular Americans

    Directory of Open Access Journals (Sweden)

    Isabella Kasselstrand

    2017-04-01

    Full Text Available The First Amendment to the United States’ Constitution addresses freedom of religion and the separation of church and state. However, the historical influence of religion in laws, policies, and political representation have left secular individuals feeling excluded. At the same time, levels of confidence in social and political institutions in the United States are at an all-time low. This begs the question: Is there a relationship between secularity and confidence in various social and political institutions (e.g. the armed forces, churches, major companies, government, police, and political parties? This question is examined using data on the United States from the World Values Survey from 1995–2011. While controlling for a range of key demographics, the findings show a negative relationship between secularity and institutional confidence. More specifically, atheists and nonreligious individuals are less likely than those who are religious to have confidence in all six institutions. Based on previous literature and the empirical evidence presented in this study, we argue that overall lower levels of institutional confidence among secular Americans is an outcome of the exclusion of such individuals from American social life. Thus, it highlights the importance of addressing the stereotypes and prejudice that this minority group faces.

  19. Measurements of total lead concentrations and of lead isotope ratios in whole blood by use of inductively coupled plasma source mass spectrometry

    International Nuclear Information System (INIS)

    Delves, H.T.; Campbell, M.J.

    1988-01-01

    Methods are described for the accurate and precise determination of total lead and its isotopic composition in whole blood using inductively coupled plasma source mass spectrometry (ICP-MS). Sensitivities of up to 3 x 10 6 counts s -1 for 208 Pb at a total lead concentration of 5 μmol l -1 (1 μg ml -1 ) enabled total blood lead levels to be measured in 4 min per sample, with a detection limit of 0.072 μmol l -1 (15 μg l -1 ). The agreement between ICP-MS and atomic absorption spectrometry (AAS) for this analysis was excellent: ICP-MS 0.996 x AAS -0.0165 μmol l -1 ; r 0.994. Isotope ratio measurements required 15 min to achieve the required accuracy and precision both of which were generally better than 0.5% for 206 Pb: 207 Pb and 208 Pb: 206 Pb isotopic lead ratios. The ICP-MS data for these ratios in ten quality control blood specimens has a mean bias relative to isotope dilution mass spectrometry of -0.412% for 206 Pb: 207 Pb ratios and of +0.055% for the 208 Pb: 206 Pb ratios. This level of accuracy and that of the total blood lead measurements is sufficient to permit application of these ICP-MS methods to environmental studies. (author)

  20. Secular Orbit Evolution in Systems with a Strong External Perturber—A Simple and Accurate Model

    Energy Technology Data Exchange (ETDEWEB)

    Andrade-Ines, Eduardo [Institute de Mécanique Céleste et des Calcul des Éphémérides—Observatoire de Paris, 77 Avenue Denfert Rochereau, F-75014 Paris (France); Eggl, Siegfried, E-mail: eandrade.ines@gmail.com, E-mail: siegfried.eggl@jpl.nasa.gov [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, 91109 Pasadena, CA (United States)

    2017-04-01

    We present a semi-analytical correction to the seminal solution for the secular motion of a planet’s orbit under gravitational influence of an external perturber derived by Heppenheimer. A comparison between analytical predictions and numerical simulations allows us to determine corrective factors for the secular frequency and forced eccentricity in the coplanar restricted three-body problem. The correction is given in the form of a polynomial function of the system’s parameters that can be applied to first-order forced eccentricity and secular frequency estimates. The resulting secular equations are simple, straight forward to use, and improve the fidelity of Heppenheimers solution well beyond higher-order models. The quality and convergence of the corrected secular equations are tested for a wide range of parameters and limits of its applicability are given.

  1. Secular and Koranic Literacies in South Asia: From Colonisation to Contemporary Practice

    Science.gov (United States)

    Maddox, Bryan

    2007-01-01

    This paper explores the distinction between "secular" and "Koranic" schooling and literacy in South Asia. It begins by tracing an archaeology of the distinction between secular "literacy" and religious "illiteracy". It locates the emergence of the distinction in the colonial census of the 19th century, in…

  2. Association of office and ambulatory blood pressure with blood lead in workers before occupational exposure.

    Science.gov (United States)

    Yang, Wen-Yi; Efremov, Ljupcho; Mujaj, Blerim; Zhang, Zhen-Yu; Wei, Fang-Fei; Huang, Qi-Fang; Thijs, Lutgarde; Vanassche, Thomas; Nawrot, Tim S; Staessen, Jan A

    2018-01-01

    In view of decreasing lead exposure and guidelines endorsing ambulatory above office blood pressure (BP) measurement, we reassessed association of BP with blood lead (BL) in 236 newly employed men (mean age, 28.6 years) without previous lead exposure not treated for hypertension. Office BP was the mean of five auscultatory readings at one visit. Twenty-four-hour BP was recorded at 15- and 30-minute intervals during wakefulness and sleep. BL was determined by inductively coupled plasma mass spectrometry. Systolic/diastolic office BP averaged 120.0/80.7 mm Hg, and the 24-hour, awake, and asleep BP 125.5/73.6, 129.3/77.9, and 117.6/65.0 mm Hg, respectively. The geometric mean of blood lead was 4.5 μg/dL (interquartile range, 2.60-9.15 μg/dL). In multivariable-adjusted analyses, effect sizes associated with BL doubling were 0.79/0.87 mm Hg (P = .11/.043) for office BP and 0.29/-0.25, 0.60/-0.10, and -0.40/-0.43 mm Hg for 24-hour, awake, and asleep BP (P ≥ .33). Neither office nor 24-hour ambulatory hypertension was related to BL (P ≥ .14). A clinically relevant white coat effect (WCE; office minus awake BP, ≥20/≥10 mm Hg) was attributable to exceeding the systolic or diastolic threshold in 1 and 45 workers, respectively. With BL doubling, the systolic/diastolic WCE increased by 0.20/0.97 mm Hg (P = .57/.046). Accounting for the presence of a diastolic WCE, reduced the association size of office diastolic BP with BL to 0.39 mm Hg (95% confidence interval, -0.20 to 1.33; P = .15). In conclusion, a cross-sectional analysis of newly hired workers before lead exposure identified the WCE as confounder of the association between office BP and BL and did not reveal any association between ambulatory BP and BL. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Blood Lead Level and Δ-Aminolevulinic Acid Dehydratase Activity in Pre-Menopausal and Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    I.R Elezaj

    2012-07-01

    Full Text Available To describe the relationship of blood lead levels (BLL and blood, δ-aminolevulinic acid dehydratase(ALAD activity and haematocrit value(Hct to menopause , were examined 17 pre-or perimenopausal (PreM and 17 postmenopausal women (PosMfrom Prishtina City, the capital ofRepublic Kosovo. The mean age of the PreM women was 28.8 years (21-46, with a mean blood lead level of 1.2 μg/dL (SD=0.583 μg/dL , the mean blood ALAD activity53.2 U/LE (SD= 2.8 U/LE and haematocrit value42.1 % (SD= 4.3 %. The mean age of the PosM women was 53.6 years (43-67, with a mean blood lead level1.9 μg/dL (SD=0.94 μg/dL, the mean blood ALAD activity 44.4 U/LE(SD=7.2 U/LE and haematocrit value 42.1 % ( SD= 4.3 % and 42.2 % (SD=4.4 %. The BPb level of PosM women was significantly higher (P<0.001 in comparison with the BPb level in PreM women. The blood ALAD activity of PosM was significantly inhibited (P<0.002 in comparison with blood ALAD activity in PreM women. The haematocrit values were relatively unchanged. There was established significantly negative correlation between BPb and blood ALAD activity (r=- 0.605; P<0.01 in the PreM women.These results support the hypothesis that release of bone lead stores increases during menopause and constitutes an internal source of exposure possibly associated with adverse health effects on women in menopause transition.

  4. Combined impact of lead, cadmium, polychlorinated biphenyls and non-chemical risk factors on blood pressure in NHANES

    International Nuclear Information System (INIS)

    Peters, Junenette L.; Patricia Fabian, M.; Levy, Jonathan I.

    2014-01-01

    High blood pressure is associated with exposure to multiple chemical and non-chemical risk factors, but epidemiological analyses to date have not assessed the combined effects of both chemical and non-chemical stressors on human populations in the context of cumulative risk assessment. We developed a novel modeling approach to evaluate the combined impact of lead, cadmium, polychlorinated biphenyls (PCBs), and multiple non-chemical risk factors on four blood pressure measures using data for adults aged ≥20 years from the National Health and Nutrition Examination Survey (1999–2008). We developed predictive models for chemical and other stressors. Structural equation models were applied to account for complex associations among predictors of stressors as well as blood pressure. Models showed that blood lead, serum PCBs, and established non-chemical stressors were significantly associated with blood pressure. Lead was the chemical stressor most predictive of diastolic blood pressure and mean arterial pressure, while PCBs had a greater influence on systolic blood pressure and pulse pressure, and blood cadmium was not a significant predictor of blood pressure. The simultaneously fit exposure models explained 34%, 43% and 52% of the variance for lead, cadmium and PCBs, respectively. The structural equation models were developed using predictors available from public data streams (e.g., U.S. Census), which would allow the models to be applied to any U.S. population exposed to these multiple stressors in order to identify high risk subpopulations, direct intervention strategies, and inform public policy. - Highlights: • We evaluated joint impact of chemical and non-chemical stressors on blood pressure. • We built predictive models for lead, cadmium and polychlorinated biphenyls (PCBs). • Our approach allows joint evaluation of predictors from population-specific data. • Lead, PCBs and established non-chemical stressors were related to blood pressure.

  5. Combined impact of lead, cadmium, polychlorinated biphenyls and non-chemical risk factors on blood pressure in NHANES

    Energy Technology Data Exchange (ETDEWEB)

    Peters, Junenette L., E-mail: petersj@bu.edu; Patricia Fabian, M., E-mail: pfabian@bu.edu; Levy, Jonathan I., E-mail: jonlevy@bu.edu

    2014-07-15

    High blood pressure is associated with exposure to multiple chemical and non-chemical risk factors, but epidemiological analyses to date have not assessed the combined effects of both chemical and non-chemical stressors on human populations in the context of cumulative risk assessment. We developed a novel modeling approach to evaluate the combined impact of lead, cadmium, polychlorinated biphenyls (PCBs), and multiple non-chemical risk factors on four blood pressure measures using data for adults aged ≥20 years from the National Health and Nutrition Examination Survey (1999–2008). We developed predictive models for chemical and other stressors. Structural equation models were applied to account for complex associations among predictors of stressors as well as blood pressure. Models showed that blood lead, serum PCBs, and established non-chemical stressors were significantly associated with blood pressure. Lead was the chemical stressor most predictive of diastolic blood pressure and mean arterial pressure, while PCBs had a greater influence on systolic blood pressure and pulse pressure, and blood cadmium was not a significant predictor of blood pressure. The simultaneously fit exposure models explained 34%, 43% and 52% of the variance for lead, cadmium and PCBs, respectively. The structural equation models were developed using predictors available from public data streams (e.g., U.S. Census), which would allow the models to be applied to any U.S. population exposed to these multiple stressors in order to identify high risk subpopulations, direct intervention strategies, and inform public policy. - Highlights: • We evaluated joint impact of chemical and non-chemical stressors on blood pressure. • We built predictive models for lead, cadmium and polychlorinated biphenyls (PCBs). • Our approach allows joint evaluation of predictors from population-specific data. • Lead, PCBs and established non-chemical stressors were related to blood pressure.

  6. Lunar nitrogen: Secular variation or mixing?

    International Nuclear Information System (INIS)

    Norris, S.J.; Wright, I.P.; Pillinger, C.T.

    1986-01-01

    The two current models to explain the nearly 40% variation of the lunar nitrogen isotopic composition are: (1) secular variation of solar wind nitrogen; and (2) a two component mixing model having a constant, heavy solar wind admixed with varying amounts of indigenous light lunar N (LLN). Both models are needed to explain the step pyrolysis extraction profile. The secular variation model proposes that the low temperature release is modern day solar wind implanted into grain surfaces, the 900 C to 1100 C release is from grain surfaces which were once exposed to the ancient solar wind but which are now trapped inside agglutinates, and the >1100 C release as spallogenic N produced by cosmic rays. The mixing model ascribes the components to solar wind, indigenous lunar N and spallogenic N respectively. An extension of either interpretation is that the light N seen in lunar breccias or deep drill cores represent conditions when more N-14 was available to the lunar surface

  7. Below background levels of blood lead impact cytokine levels in male and female mice

    International Nuclear Information System (INIS)

    Iavicoli, I.; Carelli, G.; Stanek, E.J.; Castellino, N.; Calabrese, E.J.

    2006-01-01

    A number of studies have documented that Pb exerts immunotoxic effects on T lymphocytes. In studies designed to explore this general response over a broad dose range, female Swiss mice were administered six different diets containing Pb acetate 1 day after mating. During lactation, the mothers received the same feed given during pregnancy, and the same diets were administered to the offspring for 9 months after weaning. At the end of exposure, blood Pb level in the offspring was determined, and possible changes in two type 1 cytokines (IL-2, INF-γ) and one type 2 cytokine (IL-4) in the serum were measured. At higher dietary Pb levels (40 and 400 ppm), a significant increase in IL-4 production was associated with a profound decrease in INF-γ and IL-2 production. At the lowest Pb diet level (0.02 ppm), which resulted in a blood lead level of (0.8 μg/dL), which is below background (2-3 μg/dL) values in humans, increases in INF-γ and IL-2 production along with a significant decrease in IL-4 production were observed. The findings provide evidence of a reversal of lead-induced cytokine skewing depending on the blood lead concentration. As blood lead concentration increases, there is a notable skewing toward Th2, while the pattern is reversed favoring Th1 development at lower blood lead values. The present findings are also notable since they indicate the potential for dietary Pb to have significant biological effects below normal background concentrations

  8. Review of pollutant lead decline in urban air and human blood: A case study from northwestern Europe

    Science.gov (United States)

    Petit, Daniel; Véron, Alain; Flament, Pascal; Deboudt, Karine; Poirier, André

    2015-09-01

    A review of the transient decline of pollutant lead in the air (PbA) and the blood (PbB) has been conducted in order to assess the relationship between these environmental reservoirs. We have demonstrated that PbA decreased 20 to 100 times more than PbB for the past 30 years, suggesting another significant intake besides airborne lead to explain lead accumulated in humans. This trend has also been observed in two blood surveys we have completed in 1976-1978 and 2008-2009 in northern France and Belgium. Nowadays, the mean PbB (1.5-3.5 μg/dL) remains at least 100 times higher than the estimated non-contaminated PbB. Lead isotope imprints in blood could help decipher specific contamination cases, and were coherent with the decline of PbA, but could not help discriminate the source of blood lead owing to the lack of source imprints, especially from dietary intakes. Correlations between recent PbB, isotopic imprints and the age of the subjects suggested that lead released from bones has become a significant source of lead in blood. The significant cause for human exposure to lead may have shifted from direct pollutant lead input accumulated in exogenous reservoirs (air and diet) to endogenous lead release from bone tissues consequential to metabolic calcium homeostasis and bone turnover.

  9. Secular Ethics Education as an Alternative to Religious Education--Finnish Teachers' Views

    Science.gov (United States)

    Zilliacus, Harriet; Kallioniemi, Arto

    2016-01-01

    This study provides a Finnish perspective to international discussions on religious and worldviews education through the subject of secular ethics. This subject has been offered in Finland since 1985 throughout comprehensive schools and is primarily directed at students who are non-affiliated. Secular ethics education has scarcely been researched…

  10. Comments on equilibrium, transient equilibrium, and secular equilibrium in serial radioactive decay

    International Nuclear Information System (INIS)

    Prince, J.R.

    1979-01-01

    Equations describing serial radioactive decay are reviewed along with published descriptions or transient and secular equilibrium. It is shown that terms describing equilibrium are not used in the same way by various authors. Specific definitions are proposed; they suggest that secular equilibrium is a subset of transient equilibrium

  11. High prevalence of elevated blood lead levels in both rural and urban Iowa newborns: Spatial patterns and area-level covariates.

    Science.gov (United States)

    Carrel, Margaret; Zahrieh, David; Young, Sean G; Oleson, Jacob; Ryckman, Kelli K; Wels, Brian; Simmons, Donald L; Saftlas, Audrey

    2017-01-01

    Lead in maternal blood can cross the placenta and result in elevated blood lead levels in newborns, potentially producing negative effects on neurocognitive function, particularly if combined with childhood lead exposure. Little research exists, however, into the burden of elevated blood lead levels in newborns, or the places and populations in which elevated lead levels are observed in newborns, particularly in rural settings. Using ~2300 dried bloods spots collected within 1-3 days of birth among Iowa newborns, linked with the area of mother's residence at the time of birth, we examine the spatial patterns of elevated (>5 μg/dL) blood lead levels and the ecological-level predictors of elevated blood lead levels. We find that one in five newborns exceed the 5 μg/dL action level set by the US Centers for Disease Control & Prevention (CDC). Bayesian spatial zero inflated regression indicates that elevated blood lead in newborns is associated with areas of increased pre-1940s housing and childbearing-age women with low educational status in both rural and urban settings. No differences in blood lead levels or the proportion of children exceeding 5 μg/dL are observed between urban and rural maternal residence, though a spatial cluster of elevated blood lead is observed in rural counties. These characteristics can guide the recommendation for testing of infants at well-baby appointments in places where risk factors are present, potentially leading to earlier initiation of case management. The findings also suggest that rural populations are at as great of risk of elevated blood lead levels as are urban populations. Analysis of newborn dried blood spots is an important tool for lead poisoning surveillance in newborns and can direct public health efforts towards specific places and populations where lead testing and case management will have the greatest impact.

  12. Association of umbilical cord blood lead with neonatal behavior at varying levels of exposure

    Directory of Open Access Journals (Sweden)

    Mamtani Manju R

    2006-06-01

    Full Text Available Abstract Background In the light of the ongoing debate about lowering the cut-off for acceptable blood lead level to Methods Using Brazelton's Neonatal Behavioral Assessment Scale (NBAS, an epidemiological approach and robust statistical techniques like multivariate linear regression, logistic regression, Poisson regression and structural equations modeling analyses we estimated the simultaneous indirect effects of umbilical cord blood lead (CBL levels and other neonatal covariates on the NBAS clusters. Results We observed that when analyzed in all study subjects, the CBL levels independently and strongly influenced autonomic stability and abnormal reflexes clusters. However, when the analysis was restricted to neonates with CBL Conclusion Our results further endorse the need to be cognizant of the detrimental effects of blood lead on neonates even at a low-dose prenatal exposure.

  13. Effects of environmental lead pollution on blood lead and sex hormone levels among occupationally exposed group in an E-waste dismantling area.

    Science.gov (United States)

    Yang, Yan; Lu, Xiao Song; Li, Ding Long; Yu, Yun Jiang

    2013-06-01

    To study the effects of environmental multi-media lead pollution on blood lead and sex hormone levels among lead exposed males engaged in E-waste dismantling, and the correlation between confounding factors and sex hormone levels. An E-waste dismantling area in Taizhou of Zhejiang Province was selected as the research site. One hundred and fifty two samples were collected from the groundwater, soil, rice, corn, chicken, and pork in the dismantling area. The effects of the multi-media lead pollution on the male blood lead and sex hormone levels of FSH, LH, and T, as well as the correlation with confounding factors, were studied. The blood lead concentrations in the males aged under 31, from 31 to 45 and from 46 to 60 were 98.55, 100.23, and 101.45 μg/L, respectively. Of all the environmental media lead exposures, the groundwater, rice and soil were main contributing factors to the lead accumulation in humans. FSH and LH levels increased with the age while the T levels decreased with the age instead. There was a significant correlation between the FSH and LH levels and wearing masks. There was correlation between the FSH, LH, and T levels, and the mean values of lead concentrations in environmental media, and the sex hormone levels were correlated with the confounding factor of wearing masks. Copyright © 2013 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

  14. Calling in Work: Secular or Sacred?

    Science.gov (United States)

    Steger, Michael F.; Pickering, N. K.; Shin, J. Y.; Dik, B. J.

    2010-01-01

    Recent scholarship indicates that people who view their work as a calling are more satisfied with their work and their lives. Historically, calling has been regarded as a religious experience, although modern researchers frequently have adopted a more expansive and secular conceptualization of calling, emphasizing meaning and personal fulfillment…

  15. Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys

    DEFF Research Database (Denmark)

    Andersson, Anna-Maria; Jensen, Tina K; Juul, Anders

    2007-01-01

    Adverse secular trends in male reproductive health have been reported to be reflected in increased testicular cancer risk and decreased semen quality in more recently born men. These secular trends may also be reflected by changes in Leydig cell function.......Adverse secular trends in male reproductive health have been reported to be reflected in increased testicular cancer risk and decreased semen quality in more recently born men. These secular trends may also be reflected by changes in Leydig cell function....

  16. Secularization and its Impact on the Jews’ Religious Life

    Directory of Open Access Journals (Sweden)

    Vasile Adrian

    2017-12-01

    Full Text Available Secularization brings forward a desacralized world, exclusively oriented to the material and concerned with the “fashion of the day” rather than with the Spirit of God. Secularism made man wander from god and ignore the religious, spiritual and moral principles found in Christianity and Judaism. Secularization caused all social, economic or political aspects be expressed outside these principles and, many times, against them. Man’s religiousness has become something personal and original that has nothing to do with community or the life of the community, thus becoming a strictly private or intimate option, and in many case even a taboo. Therefore we speak about a privatization of the religious feeling that has no connection to Christianity or Judaism. Unfortunately Judaism has been affected in some other way besides what concerns religious life. We are referring to the anti-Semite feeling that reached its peak at the beginning of the last century and tragically ended in the holocaust in which millions of Jews lost their lives.

  17. Increased DNA damage in blood cells of rat treated with lead as assessed by comet assay

    Directory of Open Access Journals (Sweden)

    Mohammad Arif

    2008-06-01

    Full Text Available A growing body of evidence suggests that oxidative stress is the key player in the pathogenesis of lead-induced toxicity. The present study investigated lead induced oxidative DNA damage, if any in rat blood cells by alkaline comet assay. Lead was administered intraperitoneally to rats at doses of 25, 50 and 100 mg/kg body weight for 5 days consecutively. Blood collected on day six from sacrificed lead-treated rats was used to assess the extent of DNA damage by comet assay which entailed measurement of comet length, olive tail moment, tail DNA (% and tail length. The results showed that treatment with lead significantly increased DNA damage in a dose-dependent manner. Therefore, our data suggests that lead treatment is associated with oxidative stress-induced DNA damage in rat blood cells which could be used as an early bio-marker of lead-toxicity.

  18. Changes in blood lead levels associated with use of chloramines in water treatment systems.

    Science.gov (United States)

    Miranda, Marie Lynn; Kim, Dohyeong; Hull, Andrew P; Paul, Christopher J; Galeano, M Alicia Overstreet

    2007-02-01

    More municipal water treatment plants are using chloramines as a disinfectant in order to reduce carcinogenic by-products. In some instances, this has coincided with an increase in lead levels in drinking water in those systems. Lead in drinking water can be a significant health risk. We sought to test the potential effect of switching to chloramines for disinfection in water treatment systems on childhood blood lead levels using data from Wayne County, located in the central Coastal Plain of North Carolina. We constructed a unified geographic information system (GIS) that links blood lead screening data with age of housing, drinking water source, and census data for 7,270 records. The data were analyzed using both exploratory methods and more formal multivariate techniques. The analysis indicates that the change to chloramine disinfection may lead to an increase in blood lead levels, the impact of which is progressively mitigated in newer housing. Introducing chloramines to reduce carcinogenic by-products may increase exposure to lead in drinking water. Our research provides guidance on adjustments in the local childhood lead poisoning prevention program that should accompany changes in water treatment. As similar research is conducted in other areas, and the underlying environmental chemistry is clarified, water treatment strategies can be optimized across the multiple objectives that municipalities face in providing high quality drinking water to local residents.

  19. Melatonin reduces lead levels in blood, brain and bone and increases lead excretion in rats subjected to subacute lead treatment.

    Science.gov (United States)

    Hernández-Plata, Everardo; Quiroz-Compeán, Fátima; Ramírez-Garcia, Gonzalo; Barrientos, Eunice Yáñez; Rodríguez-Morales, Nadia M; Flores, Alberto; Wrobel, Katarzina; Wrobel, Kazimierz; Méndez, Isabel; Díaz-Muñoz, Mauricio; Robles, Juvencio; Martínez-Alfaro, Minerva

    2015-03-04

    Melatonin, a hormone known for its effects on free radical scavenging and antioxidant activity, can reduce lead toxicity in vivo and in vitro.We examined the effects of melatonin on lead bio-distribution. Rats were intraperitoneally injected with lead acetate (10, 15 or 20mg/kg/day) with or without melatonin (10mg/kg/day) daily for 10 days. In rats intoxicated with the highest lead doses, those treated with melatonin had lower lead levels in blood and higher levels in urine and feces than those treated with lead alone, suggesting that melatonin increases lead excretion. To explore the mechanism underlying this effect, we first assessed whether lead/melatonin complexes were formed directly. Electronic density functional (DFT) calculations showed that a lead/melatonin complex is energetically feasible; however, UV spectroscopy and NMR analysis showed no evidence of such complexes. Next, we examined the liver mRNA levels of metallothioneins (MT) 1 and 2. Melatonin cotreatment increased the MT2 mRNA expression in the liver of rats that received the highest doses of lead. The potential effects of MTs on the tissue distribution and excretion of lead are not well understood. This is the first report to suggest that melatonin directly affects lead levels in organisms exposed to subacute lead intoxication. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  20. Childhood Blood Lead Levels and Symptoms of Attention Deficit Hyperactivity Disorder (ADHD): A Cross-Sectional Study of Mexican Children.

    Science.gov (United States)

    Huang, Siying; Hu, Howard; Sánchez, Brisa N; Peterson, Karen E; Ettinger, Adrienne S; Lamadrid-Figueroa, Héctor; Schnaas, Lourdes; Mercado-García, Adriana; Wright, Robert O; Basu, Niladri; Cantonwine, David E; Hernández-Avila, Mauricio; Téllez-Rojo, Martha María

    2016-06-01

    Previous studies suggest that blood lead levels are positively associated with attention deficit/hyperactivity disorder (ADHD) and ADHD-symptoms in children. However, the associations between lead exposure and ADHD subtypes are inconsistent and understudied. The objective of this study was to explore the association of low-level concurrent lead exposure with subtypes of ADHD symptoms in 578 Mexican children 6-13 years of age. We measured concurrent blood lead levels using inductively coupled plasma mass spectrometry (ICPMS). We administered the Conners' Rating Scales-Revised (CRS-R) to mothers to evaluate their children's ADHD symptoms. We used imputation to fill missing values in blood lead levels and used segmented regression models adjusted for relevant covariates to model the nonlinear relationship between blood lead and ADHD symptoms. Mean ± SD blood lead levels were 3.4 ± 2.9 μg/dL. In adjusted models, a 1-μg/dL increase in blood lead was positively associated with Hyperactivity and Restless-Impulsivity scores on the CRS-R scale and Hyperactivity-Impulsivity scores on the CRS-R scale of the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, but only in children with blood lead level ≤ 5 μg/dL. Blood lead was not associated with Inattentive symptoms or overall ADHD behavior. In this population of Mexican children, current blood lead level among children with low exposure (≤ 5 μg/dL) was positively associated with hyperactive/impulsive behaviors, but not with inattentiveness. These results add to the existing evidence of lead-associated neurodevelopmental deficits at low levels of exposure. Huang S, Hu H, Sánchez BN, Peterson KE, Ettinger AS, Lamadrid-Figueroa H, Schnaas L, Mercado-García A, Wright RO, Basu N, Cantonwine DE, Hernández-Avila M, Téllez-Rojo MM. 2016. Childhood blood lead levels and symptoms of attention deficit hyperactivity disorder (ADHD): a cross-sectional study of Mexican children. Environ Health Perspect 124

  1. Effects of blood lead levels on airflow limitations in Korean adults: Findings from the 5th KNHNES 2011

    International Nuclear Information System (INIS)

    Chung, Hye Kyung; Chang, Yoon Soo; Ahn, Chul Woo

    2015-01-01

    This study aimed to examine whether blood levels of heavy metals, such as lead, mercury and cadmium, are related with pulmonary function in Korean adults. This investigation included 870 Korean adults (≥40 years) who received pulmonary function testing in the Korea National Health and Nutrition Examination Survey (KNHANES) V-2, 2011. Data of blood levels of heavy metals, pulmonary function tests and anthropometric measurements were acquired. Blood lead levels showed inverse correlations with the FEV 1 /FVC ratio before (r=−0.276, p<0.001) and after adjustment of multiple compounding factors (r=−0.115, p=0.001). A logistic multiple regression analysis revealed that blood lead levels were a significant influencing factor for the FEV 1 /FVC ratio (β=−0.017, p=0.001, adjusted R 2 =0.267). The odds ratios (ORs) for the FEV 1 /FVC ratio were significantly lower in the highest tertile group of the blood lead levels than in the lowest tertile group in Model 1 (OR=0.007, 95% CI=0.000−0.329) and Model 2 (OR=0.006, 95% CI=0.000−0.286). These findings imply that environmental exposure to lead might be an important factor that may cause airflow limitations in Korean adults. - Highlights: • Blood lead levels showed inverse correlations with the FEV 1 /FVC ratio. • Blood lead level was a significant influencing factor for the FEV 1 /FVC ratio. • ORs for FEV 1 /FVC were lower in the highest blood lead group than in the lowest group. • Environmental exposure to lead might be an important factor for airflow limitations

  2. Blood Lead Level in Children with Neurological Disorders.

    Science.gov (United States)

    Parhoudeh, Marzieh; Inaloo, Soroor; Zahmatkeshan, Mozhgan; Seratishirazi, Zahra; Haghbin, Saeedeh

    2018-01-01

    We aimed to investigate the blood lead level (BLL) in children with neurologic disorders of unknown causes and compare with normal children. In this prospective case-control study, 68 patients aged 1 to 18 yr with neurologic disorders of unknown causes, were referred to pediatric neurology clinics and wards, Shiraz, Iran selected during a 12 months period from Sep 2013. They were compared with 1:1 ratio, age, and sex-matched healthy children. BLL was checked from all participants using 3 cc heparinized venous blood sample. Level of ≥5 mcg/dl was considered toxic dose. Totally, 136 children (68 cases and 68 controls) with mean ages of 5.20±4.12 and 4.18±3.86 yr, respectively, were enrolled. Mean BLL was higher in case group than in controls but the difference was not significant ( P =0.84), though they were less than toxic levels in both. In addition, the difference in mean BLLs was not significant in terms of living place, sex, and age. Totally, 17.7% of the study sample had BLL ≥5 mcg/dl. The frequency of BLL ≥5 mcg/dl was significantly higher in case group ( P =0.024) with an odds ratio 2.9 times higher (95% CI: 1.066-7.60). Strategies in public health must focus on practicing primary and secondary preventions of lead exposure in children.

  3. Habermas and the Meaning of the Post-Secular Society: Complementary Learning Processes

    Science.gov (United States)

    Welton, Michael R.

    2014-01-01

    This essay argues that if social justice is to prevail in our world, we must understand the post-secular nature of our globalized society as a prerequisite for moving beyond "might is right" to national and international relations that heed all voices towards evidence-based interaction. Our post-secular world and postmetaphysical…

  4. Surviving Secularization: Masking the Spirit in the Jankunu (John Canoe Festivals of the Caribbean

    Directory of Open Access Journals (Sweden)

    Kenneth M. Bilby

    2010-12-01

    Full Text Available Jankunu (Jonkonnu, Junkanoo, an Afro-Caribbean Yuletide tradition centering on masked dance, is generally characterized as a secular festival. This article presents contemporary ethnographic evidence showing that certain older variants of the tradition remain closely connected with African-derived religious concepts and practices. On the basis of this new evidence, the author argues for a reexamination and reevaluation of the historical significance of this tradition, which even today, despite its ostensible secularity, has vaguely "spiritual" associations for many in the region—including some of those who represent it as "secular." The article interprets this apparent contradiction as the result of a historical process of secularization (in response to the stigmatization of African modes of religiosity that was only partly successful.

  5. Blood lead concentrations in 1-3 year old Lebanese children: a cross-sectional study.

    Science.gov (United States)

    Nuwayhid, Iman; Nabulsi, Mona; Muwakkit, Samar; Kouzi, Sarah; Salem, George; Mikati, Mohamed; Ariss, Majd

    2003-04-15

    Childhood lead poisoning has not made the list of national public health priorities in Lebanon. This study aims at identifying the prevalence and risk factors for elevated blood lead concentrations (B-Pb >or= 100 microg/L) among 1-3 year old children. It also examines the need for universal blood lead screening. This is a cross-sectional study of 281 well children, presenting to the pediatric ambulatory services at the American University of Beirut Medical Center in 1997-98. Blood was drawn on participating children for lead analysis and a structured questionnaire was introduced to mothers asking about social, demographic, and residence characteristics, as well as potential risk factors for lead exposure. Children with B-Pb >or= 100 microg/L were compared to those with B-Pb or= 100 microg/L. Logistic regression analysis showed that elevated B-Pb was associated with paternal manual jobs (odds ratio [OR]: 4.74), residence being located in high traffic areas (OR: 4.59), summer season (OR: 4.39), using hot tap water for cooking (OR: 3.96), exposure to kohl (OR: 2.40), and living in older buildings (OR: 2.01). Lead screening should be offered to high-risk children. With the recent ban of leaded gasoline in Lebanon, emphasis should shift to other sources of exposure in children.

  6. Relationship of blood and bone lead to menopause and bone mineral density among middle-age women in Mexico City.

    Science.gov (United States)

    Garrido Latorre, Francisco; Hernández-Avila, Mauricio; Tamayo Orozco, Juan; Albores Medina, Carlos A; Aro, Antonio; Palazuelos, Eduardo; Hu, Howard

    2003-04-01

    To describe the relationship of blood lead levels to menopause and bone lead levels, we conducted a cross-sectional study on 232 pre- or perimenopausal (PreM) and postmenopausal (PosM) women who participated in an osteoporosis-screening program in Mexico City during the first quarter of 1995. Information regarding reproductive characteristics and known risk factors for blood lead was obtained using a standard questionnaire by direct interview. The mean age of the population was 54.7 years (SD = 9.8), with a mean blood lead level of 9.2 microg/dL (SD = 4.7/dL) and a range from 2.1 to 32.1 microg/dL. After adjusting for age and bone lead levels, the mean blood lead level was 1.98 microg/dL higher in PosM women than in PreM women (p = 0.024). The increase in mean blood lead levels peaked during the second year of amenorrhea with a level (10.35 microg/dL) that was 3.51 microg/dL higher than that of PreM women. Other important predictors of blood lead levels were use of lead-glazed ceramics, schooling, trabecular bone lead, body mass index, time of living in Mexico City, and use of hormone replacement therapy. Bone density was not associated with blood lead levels. These results support the hypothesis that release of bone lead stores increases during menopause and constitutes an internal source of exposure possibly associated with health effects in women in menopause transition.

  7. Secular chaos and its application to Mercury, hot Jupiters, and the organization of planetary systems.

    Science.gov (United States)

    Lithwick, Yoram; Wu, Yanqin

    2014-09-02

    In the inner solar system, the planets' orbits evolve chaotically, driven primarily by secular chaos. Mercury has a particularly chaotic orbit and is in danger of being lost within a few billion years. Just as secular chaos is reorganizing the solar system today, so it has likely helped organize it in the past. We suggest that extrasolar planetary systems are also organized to a large extent by secular chaos. A hot Jupiter could be the end state of a secularly chaotic planetary system reminiscent of the solar system. However, in the case of the hot Jupiter, the innermost planet was Jupiter (rather than Mercury) sized, and its chaotic evolution was terminated when it was tidally captured by its star. In this contribution, we review our recent work elucidating the physics of secular chaos and applying it to Mercury and to hot Jupiters. We also present results comparing the inclinations of hot Jupiters thus produced with observations.

  8. Secular chaos and its application to Mercury, hot Jupiters, and the organization of planetary systems

    Science.gov (United States)

    Lithwick, Yoram; Wu, Yanqin

    2014-01-01

    In the inner solar system, the planets’ orbits evolve chaotically, driven primarily by secular chaos. Mercury has a particularly chaotic orbit and is in danger of being lost within a few billion years. Just as secular chaos is reorganizing the solar system today, so it has likely helped organize it in the past. We suggest that extrasolar planetary systems are also organized to a large extent by secular chaos. A hot Jupiter could be the end state of a secularly chaotic planetary system reminiscent of the solar system. However, in the case of the hot Jupiter, the innermost planet was Jupiter (rather than Mercury) sized, and its chaotic evolution was terminated when it was tidally captured by its star. In this contribution, we review our recent work elucidating the physics of secular chaos and applying it to Mercury and to hot Jupiters. We also present results comparing the inclinations of hot Jupiters thus produced with observations. PMID:24367108

  9. Certification of lead and cadmium in three lyophilized blood materials. CRM No. 194, 195, 196

    Energy Technology Data Exchange (ETDEWEB)

    Yeoman, W B; Colinet, E; Griepink, B

    1985-01-01

    The report describes the work for certification of lead and cadmium in three lyophilized samples of bovine blood materials. Homogeneity and stability tests were carried out and are presented in the report. The concentrations of lead and cadmium in each sample of the reconstituted blood are certified. A variety of well established methods were used for certification of the materials.

  10. Prediction of secular acceleration of axial rotation of Mars

    Science.gov (United States)

    Barkin, Yu. V.

    2009-04-01

    Secular motion of the Earth pole and non-tidal acceleration of its diurnal rotation have obtained rather precise explanation with the help of simple one-point model of the directed transport of fluid masses from a southern hemisphere in northern hemisphere with the general direction, given by geocentric axis OP directed to pole P with coordinates 700N, 10403 E[1]. The another generalized model represents a system of two material points with masses m2 and m1, located on surface of the Earth at poles of geocentric axis OP. Masses are linearly changed in the time with velocities [2]: ṁ2 = 0.179 × 1015kg/yrand ṁ1 = 0.043 × 1015kg/yr. A reduction of fluid masses of the appropriate thin spherical layer of the Earth correspond to secular increasing of masses of model points. The specified model has allowed to explain values of fundamental geodynamic parameters observably and determined during decades: a direction and velocity of drift of a pole of the Earth; value of non-tidal acceleration of axial rotation; to explain a secular variations of coefficients of the second, third, fourth, sixth and eighth zonal harmonics of a geopotential; coefficients of secular changes of a surface of ocean for the last approximately 150 years; a direction of secular drift of a geocenter and other planetary phenomena [3]. The role of the angular momentum of redistributed masses of the Earth in rotation of the Earth appeared not essential at the given stage of researches. On the essence the offered model has semi-empirical character as it bases on values of velocities of change of masses of points and the given position of axis OP. For their determination and estimations the part of the observant data was used, and other parameters were designed under analytical formulas. The obtained results have precisely confirmed competency and affectivity of geodynamic model [4] about existence of secular drift of a liquid core along radial direction OP with velocity about 2.6 cm/yr in the

  11. The relationship between blood lead levels and occupational exposure in a pregnant population

    OpenAIRE

    Osmel La-Llave-León; José Manuel Salas Pacheco; Sergio Estrada Martínez; Eloísa Esquivel Rodríguez; Francisco X. Castellanos Juárez; Ada Sandoval Carrillo; Angélica María Lechuga Quiñones; Fernando Vázquez Alanís; Gonzalo García Vargas; Edna Madai Méndez Hernández; Jaime Duarte Sustaita

    2016-01-01

    Background Pregnant women exposed to lead are at risk of suffering reproductive damages, such as miscarriage, preeclampsia, premature delivery and low birth weight. Despite that the workplace offers the greatest potential for lead exposure, there is relatively little information about occupational exposure to lead during pregnancy. This study aims to assess the association between blood lead levels and occupational exposure in pregnant women from Durango, Mexico. Methods A cross-sectional stu...

  12. Blood Lead Concentrations in 1–3 Year Old Lebanese Children: A Cross-sectional study

    OpenAIRE

    Salem George; Mikati Mohamed; Kouzi Sarah; Muwakkit Samar; Nabulsi Mona; Nuwayhid Iman; Ariss Majd

    2003-01-01

    Abstract Background Childhood lead poisoning has not made the list of national public health priorities in Lebanon. This study aims at identifying the prevalence and risk factors for elevated blood lead concentrations (B-Pb ≥ 100 μg/L) among 1–3 year old children. It also examines the need for universal blood lead screening. Methods This is a cross-sectional study of 281 well children, presenting to the pediatric ambulatory services at the American University of Beirut Medical Center in 1997–...

  13. Sacralizando o secular. Os movimentos etno-fundamentalistas

    Directory of Open Access Journals (Sweden)

    Enzo Pace

    2017-10-01

    Full Text Available Os movimentos religiosos fundamentalistas encaram o Estado secular como um inimigo, porque pretendem sistematizar seu poder como se Deus não atuasse. Esses movimentos consideram sua religião como o repositório de verdade absoluta, a fonte derradeira que legitima as leis humanas. Assim, conquanto sejam pós-seculares, ao mesmo tempo tentam transformar os princípios religiosos em agendas políticas. Com efeito, os militantes agem frequentemente de acordo com princípios políticos, procurando afirmar o primado de sua própria fé sobre a dos outros. Eles se movem dentro das sociedades contemporâneas em nome de uma teologia política radical. Os principais argumentos baseiam-se em dois estudos de caso: o Bodu Bala Sena no Sri Lanka e os movimentos para o Hindutva na Índia.

  14. A secular technetium–molybdenum generator

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Wagner L., E-mail: wagnerleite@ufmg.br; Campos, Tarcisio P.R., E-mail: tprcampos@pq.cnpq.br

    2015-05-11

    A compact secular molybdenium generator is subject of this paper. This generator represents a nuclear system that comprises a hydrogen-isotopes fusor, moderator, reflector and shield. Deuterium fusion reactions in a tritiated or deuterated target provide the neutron source. A moderation fluid slowdown the neutron energy which increases {sup 98}Mo(n,γ){sup 99}Mo capture reaction rates. Neutron reflection minimizes the neutron escape and the radiation shield encloses the device. The neutron yield calculation along with electromagnetic and nuclear simulations were addressed. Results revealed the accelerator equipotential surfaces ranging from −30 to 150 kV, the ion trajectories and the energy beam profile define a deuteron current of 1 A with energy of 180 keV at the target, the spatial distribution of the neutron flux, and the {sup 99}Mo and {sup 99m}Tc activities in function of transmuter operation time. The kinetics of the {sup 99m}Tc correlated to its precursor activity demonstrates a secular equilibrium providing 2 Ci in a operational time of 150 h. As conclusion, the investigated nuclear and electromagnetic features have demonstrated that such generator shall have a notable potential for feeding the {sup 99m}Tc clinical application.

  15. What Lies between the Religious and the Secular?: Education beyond the Human

    Science.gov (United States)

    Seo, Yong-Seok

    2014-01-01

    The current age is characterised by many as secular, and a source of such a characterisation can be found in the Nietzschean claim that thoughts about there being some ultimate reality have to be jettisoned, and human existence and the world need to be embraced as they are. That claim is renewed by some secular thinkers who insist that education…

  16. Blood lead levels and bone turnover with weight reduction in women

    OpenAIRE

    RIEDT, CLAUDIA S.; BUCKLEY, BRIAN T.; BROLIN, ROBERT E.; AMBIA-SOBHAN, HASINA; RHOADS, GEORGE G.; SHAPSES, SUE A.

    2008-01-01

    High bone turnover states are known to raise blood lead levels (BPb). Caloric restriction will increase bone turnover, yet it remains unknown if weight reduction increases BPb due to mobilization of skeletal stores. We measured whole blood Pb levels (206Pb) by inductively coupled plasma mass spectrometry in 73 women (age 24–75 years; BMI 23– 61 kg/m2) before and after 6 months of severe weight loss (S-WL), moderate weight loss (M-WL), or weight maintenance (WM). Baseline BPb levels were relat...

  17. Public debt, secular stagnation and functional finance

    DEFF Research Database (Denmark)

    Skott, Peter

    2016-01-01

    Fiscal policy and public debt may be required to maintain full employment and avoid secular stagnation. This conclusion emerges from a range of different models, including OLG specifications and stock-flow consistent (post-) Keynesian models. One of the determinants of the required long-run debt ...

  18. Distinguish natural sources out of secular equilibrium with their parents or daughters in Gamma ray spectrum analyses

    International Nuclear Information System (INIS)

    Mao Yahong; Liu Yigang

    2005-01-01

    Objective: To determine materials containing natural radionuclides in or out secular equilibrium with their parents or daughters. Methods: In gamma ray spectrum analyses, the activity concentration of every daughter is the same as that of its parent when the material is in secular equilibrium. The activity concentrations of daughters and their parents are different when the material is out of secular equilibrium. Results: It is different to determine whether the exposures from these materials should be exempted that materials containing natural radionuclides are in or out of secular equilibrium with their parents or daughters. Conclusion: It is important to determine materials containing natural radionuclides in or out secular equilibrium with their parents or daughters in gamma ray spectrum analyses. (authors)

  19. Secular Love number of Phobos

    International Nuclear Information System (INIS)

    Bursa, M.

    1988-01-01

    The secular Love number of Phobos was estimated k s =10.4. It only deviates by one order of magnitude from that corresponding to the ideal equilibrium state. It is not in contradiction with the theory of the origin of Phobos as a result of the accretion around Mars. In its early history, the rotation period of Phobos had been estimated to be approx. 2.4 hours. (author). 1 tab., 4 refs

  20. Evaluation of potentially significant increase of lead in the blood during long-term bed rest and space flight.

    Science.gov (United States)

    Kondrashov, Vladislav; Rothenberg, Stephen J; Chettle, David; Zerwekh, Joseph

    2005-02-01

    We address a gap in the knowledge of lead turnover under conditions of prolonged bed rest and microgravity by developing a quantitative model of the amount of lead returned to blood circulation from bone. We offer the hypothesis that skeletal unloading, such as typically occurs during extended bed rest or microgravity, will result in bone lead being released to the blood, as has already been demonstrated in the case of calcium. We use initial bone lead concentrations to develop predictive models of blood lead elevation. Our theoretical calculations with typical bone lead loads measured in today's 40-60-year-old generation, suggest that the estimated blood lead concentrations in long duration (e.g., 100 days) space flight could average between 20 and 40 microg dl(-1), a range with well-established toxic effects. For a similar duration of bed rest, estimated blood lead concentration could be as high as 10-20 microg dl(-1), which is a level of concern, particularly if we consider females of childbearing age. The preliminary experimental results were obtained under multi-institutional collaborations, with the main outcome received from an on-going bed rest study, Prevention of Microgravity-Induced Stone Risk by KMgCitrate, conducted at the General Clinical Research Center (GCRC) of the University of Texas Southwestern Medical Center, Dallas. Based on theoretical modeling and some preliminary experimental results, this concept may have important clinical implications by allowing prediction of the magnitude of blood lead elevation, thereby establishing the means to prevent lead toxicity during long duration space flight of astronauts and in conditions of prolonged bed rest such as complicated pregnancy, spinal cord injury induced paralysis and comatose patients.

  1. Perils of the Future: A Discussion of Marx’s Secularization Thesis

    Directory of Open Access Journals (Sweden)

    Clava Brodsky

    2014-07-01

    Full Text Available As both a journalist and a philosopher, Karl Marx had one eye on the present and the other on the future. This dual concern is particularly clear in On the Jewish Question, where Marx persons his theory of secularization. In this article, I claim that his account of political secularization is far more convincing; while his account of human emancipation – his wish for the future – rests on a thin reading of human rights.

  2. Blood lead level studies by the Public Health Service in an industrial stress area

    Energy Technology Data Exchange (ETDEWEB)

    Jantzen, G.

    1981-12-01

    The general directions of the European Community concerning lead resulted to be useful for analysing the biologic impact on the population living in an industrial immission area and for differentiating within this locality affected and non-affected residential districts. Consequently the social-hygienic and regional-hygienic measures are limited and justified territorially. The environmental parameters, their relation to the distance at which an industrial plant is situated and the blood lead values are indicated. Recommendations are given, which concern the protection of health and even the reconstruction of the residential area by immission-reducing measures. It was found that the lead impact on children is higher than that on grown-ups. Tables illustrate the symptomatology of lead impacts, its relation to blood lead concentration, the degree of impact measured in children and grown-ups and the corresponding necessary measures as auxiliary methods for the Public Health Service and the physicians.

  3. Secular Extragalactic Parallax and Geometric Distances with Gaia Proper Motions

    Science.gov (United States)

    Paine, Jennie; Darling, Jeremiah K.

    2018-06-01

    The motion of the Solar System with respect to the cosmic microwave background (CMB) rest frame creates a well measured dipole in the CMB, which corresponds to a linear solar velocity of about 78 AU/yr. This motion causes relatively nearby extragalactic objects to appear to move compared to more distant objects, an effect that can be measured in the proper motions of nearby galaxies. An object at 1 Mpc and perpendicular to the CMB apex will exhibit a secular parallax, observed as a proper motion, of 78 µas/yr. The relatively large peculiar motions of galaxies make the detection of secular parallax challenging for individual objects. Instead, a statistical parallax measurement can be made for a sample of objects with proper motions, where the global parallax signal is modeled as an E-mode dipole that diminishes linearly with distance. We present preliminary results of applying this model to a sample of nearby galaxies with Gaia proper motions to detect the statistical secular parallax signal. The statistical measurement can be used to calibrate the canonical cosmological “distance ladder.”

  4. Religion, Education and the Post-Secular Child

    Science.gov (United States)

    Davis, Robert A.

    2014-01-01

    This essay endeavours to reframe current discussion of the relationship of religion to education by highlighting an often seriously neglected element of contemporary educational thought: the changing, post-secular understanding of childhood in the globalised age. Drawing upon recent ethnographies of childhood, and an older anthropological…

  5. Spirituality and secularization: nursing and the sociology of religion.

    Science.gov (United States)

    Paley, John

    2008-01-01

    The concept of spirituality is much discussed in the UK nursing literature, despite the fact that Britain is one of the most secular countries in the world, and steadily becoming more so. Here, I pose the following question: given this increasing secularization, what accounts for the current interest in spirituality among UK nurses? The literature on spirituality in nursing has blossomed in the last 10 years, and various attempts have been made to define 'spirituality', 'spiritual need' and 'spiritual care'. Most definitions distinguish between 'spirituality' and 'religion', acknowledging that the latter is more institutional, and theologically more restrictive, than the former; and they suggest that spirituality is universal, something which (unlike religion) all human beings share. I draw on the sociology of religion - neglected, for the most part, in the nursing literature - to establish two main points. Firstly, that the UK and the USA are at opposite ends of the religion/secularity spectrum, implying that it is a mistake to assimilate USA and UK sources. Secondly, that the concept of spirituality, as currently understood, is of very recent origin, and is still 'under construction', having become separated from its associations with Christian piety and mysticism only since the 1980s. The extension of spirituality into secular domains is part of a professionalization project in nursing, a claim to jurisdiction over a newly invented sphere of work. For the time being, it remains an academic project (in the UK) as it is not one with which many clinicians identify. Relevance to clinical practice. What counts as 'spiritual need' or 'spiritual care' may not be the same in both countries, and UK clinicians are unlikely to welcome the role of surrogate chaplain, which their USA colleagues are apparently willing to embrace.

  6. Blood lead level association with lower body weight in NHANES 1999–2006

    International Nuclear Information System (INIS)

    Scinicariello, Franco; Buser, Melanie C.; Mevissen, Meike; Portier, Christopher J.

    2013-01-01

    Background: Lead exposure is associated with low birth-weight. The objective of this study is to determine whether lead exposure is associated with lower body weight in children, adolescents and adults. Methods: We analyzed data from NHANES 1999–2006 for participants aged ≥ 3 using multiple logistic and multivariate linear regression. Using age- and sex-standardized BMI Z-scores, overweight and obese children (ages 3–19) were classified by BMI ≥ 85th and ≥ 95th percentiles, respectively. The adult population (age ≥ 20) was classified as overweight and obese with BMI measures of 25–29.9 and ≥ 30, respectively. Blood lead level (BLL) was categorized by weighted quartiles. Results: Multivariate linear regressions revealed a lower BMI Z-score in children and adolescents when the highest lead quartile was compared to the lowest lead quartile (β (SE) = − 0.33 (0.07), p < 0.001), and a decreased BMI in adults (β (SE) = − 2.58 (0.25), p < 0.001). Multiple logistic analyses in children and adolescents found a negative association between BLL and the percentage of obese and overweight with BLL in the highest quartile compared to the lowest quartile (OR = 0.42, 95% CI: 0.30–0.59; and OR = 0.67, 95% CI: 0.52–0.88, respectively). Adults in the highest lead quartile were less likely to be obese (OR = 0.42, 95% CI: 0.35–0.50) compared to those in the lowest lead quartile. Further analyses with blood lead as restricted cubic splines, confirmed the dose-relationship between blood lead and body weight outcomes. Conclusions: BLLs are associated with lower body mass index and obesity in children, adolescents and adults. - Highlights: • NHANES analysis of BLL and body weight outcomes • Increased BLL associated with decreased body weight in children and adolescent • Increased BLL associated with decreased body weight in adults

  7. Blood lead level association with lower body weight in NHANES 1999–2006

    Energy Technology Data Exchange (ETDEWEB)

    Scinicariello, Franco, E-mail: fes6@cdc.gov [Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, GA 30341 (United States); Buser, Melanie C. [Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, GA 30341 (United States); Mevissen, Meike [Division of Veterinary Pharmacology and Toxicology, Vetsuisse Faculty, University of Bern, 3012 Bern (Switzerland); Portier, Christopher J. [National Center for Environmental Health (NCEH)/ATSDR, CDC, Atlanta, GA 30341 (United States)

    2013-12-15

    Background: Lead exposure is associated with low birth-weight. The objective of this study is to determine whether lead exposure is associated with lower body weight in children, adolescents and adults. Methods: We analyzed data from NHANES 1999–2006 for participants aged ≥ 3 using multiple logistic and multivariate linear regression. Using age- and sex-standardized BMI Z-scores, overweight and obese children (ages 3–19) were classified by BMI ≥ 85th and ≥ 95th percentiles, respectively. The adult population (age ≥ 20) was classified as overweight and obese with BMI measures of 25–29.9 and ≥ 30, respectively. Blood lead level (BLL) was categorized by weighted quartiles. Results: Multivariate linear regressions revealed a lower BMI Z-score in children and adolescents when the highest lead quartile was compared to the lowest lead quartile (β (SE) = − 0.33 (0.07), p < 0.001), and a decreased BMI in adults (β (SE) = − 2.58 (0.25), p < 0.001). Multiple logistic analyses in children and adolescents found a negative association between BLL and the percentage of obese and overweight with BLL in the highest quartile compared to the lowest quartile (OR = 0.42, 95% CI: 0.30–0.59; and OR = 0.67, 95% CI: 0.52–0.88, respectively). Adults in the highest lead quartile were less likely to be obese (OR = 0.42, 95% CI: 0.35–0.50) compared to those in the lowest lead quartile. Further analyses with blood lead as restricted cubic splines, confirmed the dose-relationship between blood lead and body weight outcomes. Conclusions: BLLs are associated with lower body mass index and obesity in children, adolescents and adults. - Highlights: • NHANES analysis of BLL and body weight outcomes • Increased BLL associated with decreased body weight in children and adolescent • Increased BLL associated with decreased body weight in adults.

  8. Secularities, Diversities and Pluralities: Understanding the Challenges of Religious Diversity in Latin America

    Directory of Open Access Journals (Sweden)

    Edgar Zavala-Pelayo

    2016-04-01

    Full Text Available Latin America is experiencing today the greatest religious diversity in its entire history. However, it must also be noted that a large number of the growing religious minorities may be classified into types of Christianity with conservative overtones. In this paper we will suggest that the literature streams on multiple secularities in contemporary (Western societies and religious diversity in Latin America do offer insightful perspectives yet fail to adequately convey the challenges raised by the religious across contemporary Latin America. Addressing Latin America’s historical background, we will distinguish conceptually and empirically among different degrees of secularities, diversities and pluralities and will construct with these distinctions a descriptive-normative model that can guide future analyses of secular and religious phenomena in Latin America. It is only through a comprehensive understanding of diversities, pluralities and secularities that the debates on those human rights crucial for social inclusion—from sexual and reproductive rights to gender and religious equality—can be fruitfully conducted in and beyond Latin America.

  9. Blood lead level in dogs from urban and rural areas of India and its relation to animal and environmental variables

    International Nuclear Information System (INIS)

    Balagangatharathilagar, M.; Swarup, D.; Patra, R.C.; Dwivedi, S.K.

    2006-01-01

    Lead is a common environmental pollutant with deleterious health effects on human and animal. Industrial and other human activities enhance the lead level in the environment leading to its higher residues in exposed population. The present study was aimed at determining blood lead concentration in dogs from two urban areas and in surrounding rural areas of India and analyzing lead level in dogs in relation to environmental (urban/ rural) and animal (age, sex, breed and housing) variables. Blood samples were collected from 305 dogs of either sex from urban (n = 277) and unpolluted rural localities (n = 28). Irrespective of breed, age and sex, the urban dogs had significantly (P < 0.01) higher mean blood lead concentration (0.25 ± 0.01 μg/ml) than rural dogs (0.10 ± 0.01 μg/ml). The mean blood lead level in stray dogs either from urban or rural locality (0.27 ± 0.01 μg/ml) was significantly (P < 0.01) higher than that of pets (0.20 ± 0.01 μg/ml), and the blood lead concentration was significantly higher in nondescript dogs (0.25 ± 0.01 μg/ml) than pedigreed dogs (0.20 ± 0.01 μg/ml). The locality (urban/rural) was the major variable affecting blood lead concentration in dogs. Breed and housing of the dogs of urban areas and only housing (pet/stray) in rural areas significantly (P < 0.01) influenced the blood lead concentration in dogs

  10. Ultratrace determination of lead in whole blood using electrothermal atomization laser-excited atomic fluorescence spectrometry.

    Science.gov (United States)

    Wagner, E P; Smith, B W; Winefordner, J D

    1996-09-15

    Laser-excited atomic fluorescence has been used to detect lead that was electrothermally atomized from whole blood in a graphite furnace. A 9 kHz repetition rate copper vapor laser pumped dye laser was used to excite the lead at 283.3 nm, and the resulting atomic fluorescence was detected at 405.8 nm. No matrix modification was used other than a 1:21 dilution of the whole blood with high-purity water. Using the atomic fluorescence peak area as the analytical measure and a background correction technique based upon a simultaneous measurement of the transmitted laser intensity, excellent agreement for NIST and CDC certified whole blood reference samples was obtained with aqueous standards. A limit of detection in blood of 10 fg/mL (100 ag absolute) was achieved.

  11. Environmental lead pollution and elevated blood lead levels among children in a rural area of China.

    Science.gov (United States)

    Lin, Sihao; Wang, Xiaorong; Yu, Ignatius Tak Sun; Tang, Wenjuan; Miao, Jianying; Li, Jin; Wu, Siying; Lin, Xing

    2011-05-01

    We investigated environmental lead pollution and its impact on children's blood lead levels (BLLs) in a rural area of China. In 2007, we studied 379 children younger than 15 years living in 7 villages near lead mines and processing plants, along with a control group of 61 children from another village. We determined their BLLs and collected environmental samples, personal data, and information on other potential exposures. We followed approximately 86% of the children who had high BLLs (> 15 μg/dL) for 1 year. We determined factors influencing BLLs by multivariate linear regression. Lead concentrations in soil and household dust were much higher in polluted villages than in the control village, and more children in the polluted area than in the control village had elevated BLLs (87%, 16.4 μg/dL vs 20%, 7.1 μg/dL). Increased BLL was independently associated with environmental lead levels. We found a significant reduction of 5 micrograms per deciliter when we retested children after 1 year. Our data show that the lead industry caused serious environmental pollution that led to high BLLs in children living nearby.

  12. Geomagnetic secular variation in India-regional and local features

    International Nuclear Information System (INIS)

    Srivastava, B.J.; Abbas, H.

    1977-01-01

    A study of the secular variation in the geomagnetic elements H, Z, F and D at Colaba (Bombay)-Alibag for the period 1848-1973, has been made. Fifth degree polynomials are fitted to the data of annual mean values of H, Z and F, and third degree to D, and the residuals discussed. The trends are also examined at the six Indian observatories using the data for 1960-1974. The increasing trend of Z at Alibag is found to decrease from about 1937, while that of H and F from 1965 at 20-30 nT/year, it being of the same order at Sabhawala and Hyderabad but smaller at the equatorial stations, particularly for Z component. The westward annual change in D swings eastward again around 1965 at all the Indian stations. This reversal of the secular variation trend in India after 1965 emerges as an important regional feature connected with a southward migration of the dip equator in India from 1968. The secular change in D at Alibag (+0.4'/year) is somewhat anomalous in the sense that it is reduced as compared to Hyderabad and other stations (+1.6'/year), probably due to the local magnetic anomaly of the Deccan lavas, and calls for detailed investigations. (auth.)

  13. Concentration of Lead, Mercury, Cadmium, Aluminum, Arsenic and Manganese in Umbilical Cord Blood of Jamaican Newborns

    Directory of Open Access Journals (Sweden)

    Mohammad H. Rahbar

    2015-04-01

    Full Text Available The objective of this study was to characterize the concentrations of lead, mercury, cadmium, aluminum, and manganese in umbilical cord blood of Jamaican newborns and to explore the possible association between concentrations of these elements and certain birth outcomes. Based on data from 100 pregnant mothers and their 100 newborns who were enrolled from Jamaica in 2011, the arithmetic mean (standard deviation concentrations of cord blood lead, mercury, aluminum, and manganese were 0.8 (1.3 μg/dL, 4.4 (2.4 μg/L, 10.9 (9.2 μg/L, and 43.7 (17.7 μg/L, respectively. In univariable General Linear Models, the geometric mean cord blood aluminum concentration was higher for children whose mothers had completed their education up to high school compared to those whose mothers had any education beyond high school (12.2 μg/L vs. 6.4 μg/L; p < 0.01. After controlling for maternal education level and socio-economic status (through ownership of a family car, the cord blood lead concentration was significantly associated with head circumference (adjusted p < 0.01. Our results not only provide levels of arsenic and the aforementioned metals in cord blood that could serve as a reference for the Jamaican population, but also replicate previously reported significant associations between cord blood lead concentrations and head circumference at birth in other populations.

  14. Concentration of Lead, Mercury, Cadmium, Aluminum, Arsenic and Manganese in Umbilical Cord Blood of Jamaican Newborns

    Science.gov (United States)

    Rahbar, Mohammad H.; Samms-Vaughan, Maureen; Dickerson, Aisha S.; Hessabi, Manouchehr; Bressler, Jan; Coore Desai, Charlene; Shakespeare-Pellington, Sydonnie; Reece, Jody-Ann; Morgan, Renee; Loveland, Katherine A.; Grove, Megan L.; Boerwinkle, Eric

    2015-01-01

    The objective of this study was to characterize the concentrations of lead, mercury, cadmium, aluminum, and manganese in umbilical cord blood of Jamaican newborns and to explore the possible association between concentrations of these elements and certain birth outcomes. Based on data from 100 pregnant mothers and their 100 newborns who were enrolled from Jamaica in 2011, the arithmetic mean (standard deviation) concentrations of cord blood lead, mercury, aluminum, and manganese were 0.8 (1.3 μg/dL), 4.4 (2.4 μg/L), 10.9 (9.2 μg/L), and 43.7 (17.7 μg/L), respectively. In univariable General Linear Models, the geometric mean cord blood aluminum concentration was higher for children whose mothers had completed their education up to high school compared to those whose mothers had any education beyond high school (12.2 μg/L vs. 6.4 μg/L; p < 0.01). After controlling for maternal education level and socio-economic status (through ownership of a family car), the cord blood lead concentration was significantly associated with head circumference (adjusted p < 0.01). Our results not only provide levels of arsenic and the aforementioned metals in cord blood that could serve as a reference for the Jamaican population, but also replicate previously reported significant associations between cord blood lead concentrations and head circumference at birth in other populations. PMID:25915835

  15. Long-term lead elimination from plasma and whole blood after poisoning.

    Science.gov (United States)

    Rentschler, Gerda; Broberg, K; Lundh, T; Skerfving, S

    2012-04-01

    Blood lead (B-Pb), one of the most used toxicological biomarker all kind, has serious limitations. Thus, the objective is to evaluate whether plasma lead (P-Pb) is more adequate. A long-term follow-up study of five cases of lead poisoning. P-Pb was analysed by inductively coupled plasma mass spectrometry. Kinetics after end of exposure was modelled. P-Pb at severe poisoning was about 20 μg/L; haematological effects at about 5 μg/L. Biological half-time of P-Pb was about 1 month; B-Pb decay was much slower. P-Pb is a valuable biomarker of exposure to and risk, particularly at high exposure.

  16. Blood Lead Levels in Children and Environmental Lead Contamination in Miami Inner City, Florida

    Directory of Open Access Journals (Sweden)

    Theophile Niyonsenga

    2006-09-01

    Full Text Available Studies have shown that the environmental conditions of the home are important predictors of health, especially in low-income communities. Understanding the relationship between the environment and health is crucial in the management of certain diseases. One health outcome related to the home environment among urban, minority, and low-income children is childhood lead poisoning. The most common sources of lead exposure for children are lead paint in older, dilapidated housing and contaminated dust and soil produced by accumulated residue of leaded gasoline. Blood lead levels (BLL as low as 10 μg/dL in children are associated with impaired cognitive function, behavior difficulties, and reduced intelligence. Recently, it is suggested that the standard for intervention be lowered to BLL of 5 μg /dl. The objectives of our report were to assess the prevalence of lead poisoning among children under six years of age and to quantify and test the correlations between BLL in children and lead exposure levels in their environment. This cross-sectional analysis was restricted to 75 children under six years of age who lived in 6 zip code areas of inner city Miami. These locations exhibited unacceptably high levels of lead dust and soil in areas where children live and play. Using the 5 μg/dL as the cutoff point, the prevalence of lead poisoning among the study sample was 13.33%. The study revealed that lead levels in floor dust and window sill samples were positively and significantly correlated with BLL among children (p < 0.05. However, the correlations between BLL and the soil, air, and water samples were not significant. Based on this pilot study, a more comprehensive environmental study in surrounding inner city areas is warranted. Parental education on proper housecleaning techniques may also benefit those living in the high lead-exposed communities of inner city Miami.

  17. Striking Seasonality in the Secular Warming of the Northern Continents: Structure and Mechanisms

    Science.gov (United States)

    Nigam, S.; Thomas, N. P.

    2017-12-01

    The linear trend in twentieth-century surface air temperature (SAT)—a key secular warming signal— exhibits striking seasonal variations over Northern Hemisphere continents; SAT trends are pronounced in winter and spring but notably weaker in summer and fall. The SAT trends in historical twentieth-century climate simulations informing the Intergovernmental Panel for Climate Change's Fifth Assessment show varied (and often unrealistic) strength and structure, and markedly weaker seasonal variation. The large intra-ensemble spread of winter SAT trends in some historical simulations was surprising, especially in the context of century-long linear trends, with implications for the detection of the secular warming signal. The striking seasonality of observed secular warming over northern continents warrants an explanation and the representation of related processes in climate models. Here, the seasonality of SAT trends over North America is shown to result from land surface-hydroclimate interactions and, to an extent, also from the secular change in low-level atmospheric circulation and related thermal advection. It is argued that the winter dormancy and summer vigor of the hydrologic cycle over middle- to high-latitude continents permit different responses to the additional incident radiative energy from increasing greenhouse gas concentrations. The seasonal cycle of climate, despite its monotony, provides an expanded phase space for the exposition of the dynamical and thermodynamical processes generating secular warming, and an exceptional cost-effective opportunity for benchmarking climate projection models.

  18. Secular and Religious Social Support Better Protect Blacks than Whites against Depressive Symptoms.

    Science.gov (United States)

    Assari, Shervin; Moghani Lankarani, Maryam

    2018-05-04

    Purpose: Although the protective effect of social support against depression is well known, limited information exists on racial differences in this association. The current study examined Black-White differences in the effects of religious and secular emotional social support on depressive symptoms in a national sample of older adults in the United States. Methods: With a longitudinal prospective design, the Religion, Aging and Health Survey, 2001⁻2004, followed 1493 Black ( n = 734) and White ( n = 759) elderly individuals (age 66 and older) for three years. Race, demographics (age and gender), socio-economics (education and marital status) and frequency of church attendance were measured at baseline in 2001. Secular social support, religious social support, chronic medical conditions and depressive symptoms [8- item Center for Epidemiological Studies-Depression scale (CES-D)] were measured in 2004. Multiple linear regression models were used for data analysis. In the pooled sample, secular and religious social support were both protective against depressive symptoms, net of all covariates. Race interacted with secular ( β = −0.62 for interaction) and religious ( β = −0.21 for interaction) social support on baseline depressive symptoms ( p social support on depressive symptoms was larger for Blacks ( β = −0.64) than Whites ( β = −0.16). Conclusion: We found Black—White differences in the protective effects of secular and religious social support against depressive symptoms. Blacks seem to benefit more from the same level of emotional social support, regardless of its source, compared to Whites.

  19. Strong positive association of traditional Asian-style diets with blood cadmium and lead levels in the Korean adult population.

    Science.gov (United States)

    Park, Sunmin; Lee, Byung-Kook

    2013-12-01

    Blood lead and cadmium levels are more than twofold to fivefold higher in the Korean population compared to that of the USA. This may be related to the foods consumed. We examined which food categories are related to blood lead and cadmium levels in the Korean adult population using the 2008-2010 Korean National Health and Nutrition Examination Survey (n = 5504). High and moderate consumption of bread and crackers, potatoes, meat and meat products, milk and dairy products, and pizza and hamburger resulted in significantly lower odds ratios for blood lead levels than their low consumption. However, consumption of salted fish, white fish, green vegetables, white and yellow vegetables, coffee, and alcohol resulted in significantly higher odds ratios of blood lead and cadmium. In conclusion, the typical Asian diet based on rice, fish, vegetables, regular coffee, and alcoholic drinks may be associated with higher blood cadmium and lead levels. This study suggests that lead and cadmium contents should be monitored and controlled in agricultural products to reduce health risks from heavy metals.

  20. Effects of blood lead level on biochemical and hematological parameters in children with neurological diseases of Western Maharashtra, India.

    Science.gov (United States)

    Pratinidhi, Shilpa A; Patil, Arun J; Behera, Manaskumar; Patil, Maya; Ghadage, Dnyaneshwari P; Pratinidhi, Asha K

    2014-05-01

    Lead is found in small but appreciable quantities in air, soil, drinking water, and food. Exposure to such amounts of lead does not lead to acute lead toxicity but produces subtle effects particularly in children. The aim of this study was to investigate the effects of blood lead level on biochemical and hematological parameters in children with neurological diseases in Western Maharashtra, India, and to estimate the blood lead level by liver and kidney function tests and hematological parameters in children with neurological disorders admitted to the pediatric ward and compare them with healthy controls. In this study, 30 children with various neurological disorders admitted to the pediatric ward of Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India, were compared with 30 age- and sex-matched healthy controls. Four milliliters of venous blood was collected for estimation of blood lead level, and biochemical and hematological parameters were determined using standard methods. Blood lead level was significantly increased in the study group (plead levels, there was a significant difference between the groups. All other biochemical and hematological parameters were not significantly altered in the study group as compared to the control group. Neurologically challenged children are more vulnerable to lead intoxication. It is imperative for the parents to take extra care of their children's food habits and limit hand-to-mouth activities to prevent lead intoxication.

  1. Post-Secularism, Religious Knowledge and Religious Education

    Science.gov (United States)

    Carr, David

    2012-01-01

    Post-secularism seems to follow in the wake of other (what are here called) "postal" perspectives--post-structuralism, postmodernism, post-empiricism, post-positivism, post-analytical philosophy, post-foundationalism and so on--in questioning or repudiating what it takes to be the epistemic assumptions of "modernism." To be sure, post-secularism…

  2. Aggregate demand, functional finance and secular stagnation

    DEFF Research Database (Denmark)

    Skott, Peter

    2016-01-01

    This paper makes three main points. Fiscal policy, first, may be needed in the long run to maintain full employment and avoid secular stagnation. If fiscal policy is used in this way, second, the long-run debt ratio depends (i) inversely on the rate of growth, (ii) inversely on government consump...

  3. The Role of Interreligious and Interfaith Dialogue in the Post-Secular World

    Directory of Open Access Journals (Sweden)

    Biljana Popovska

    2017-07-01

    Full Text Available Today, western liberal democratic societies are secular, or in other words, religion is set apart from the state. However, the beginning of the 21st century has seen a re-politicizing of the religion. This paper argues that religion plays an important role in current global politics and events. Moreover, it has been used as tool to recruit masses for a wrong cause. Hence, Interreligious and interfaith dialog can play a role of catalysts and a future trend in cultural diplomacy. The paper provides definitions of a secular and post secular society. Then, it discusses the general concept of dialogue and explores it from an interreligious and interfaith point of view as a way to mitigate the role religion has undertaken. Finally, it provides examples of what European Union has been doing in that respect.

  4. High blood lead levels are associated with lead concentrations in households and day care centers attended by Brazilian preschool children.

    Science.gov (United States)

    da Rocha Silva, Júlia Prestes; Salles, Fernanda Junqueira; Leroux, Isabelle Nogueira; da Silva Ferreira, Ana Paula Sacone; da Silva, Agnes Soares; Assunção, Nilson Antonio; Nardocci, Adelaide Cassia; Sayuri Sato, Ana Paula; Barbosa, Fernando; Cardoso, Maria Regina Alves; Olympio, Kelly Polido Kaneshiro

    2018-08-01

    A previous study observed high blood lead levels (BLL) in preschool children attending 50 day care centers (DCC) in São Paulo, Brazil. To identify whether lead levels found in both homes and DCC environments are associated with high blood lead levels. Children attending 4 DCCs, quoted here as NR, VA, PS and PF, were divided into two groups according to BLL: high exposure (HE: ≥13.9 μg/dL; 97.5 percentile of the 2013 year sample) and low exposure (LE: 600 μg/g, whereas such levels were observed in 77.1% of NR playground measurements. In VA DCC, 22% and 23% of the measurements in the building and in the playgrounds had levels higher than 600 μg/g, respectively. The percentage of high lead levels in the children's houses of the LE group was 5.9% (95% CI: 4.3-7.6%) and 13.2 (95% CI: 8.3-18.0%) in the HE group. Moreover, a significant association was found between high BLLs and lead levels found both in households and DCCs (p < 0.001). Most of the high lead measurements were found in tiles and playground equipment. Lead exposure estimated from the DCCs, where children spend about 10 h/day, can be as relevant as their household exposure. Therefore, public authorities should render efforts to provide a rigorous surveillance for lead-free painting supplies and for all objects offered to children. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Maternal hemochromatosis gene H63D single-nucleotide polymorphism and lead levels of placental tissue, maternal and umbilical cord blood

    Energy Technology Data Exchange (ETDEWEB)

    Kayaalti, Zeliha, E-mail: kayaalti@ankara.edu.tr [Ankara University, Institute of Forensic Sciences, Ankara (Turkey); Kaya-Akyüzlü, Dilek [Ankara University, Institute of Forensic Sciences, Ankara (Turkey); Söylemez, Esma [Ankara University, Institute of Forensic Sciences, Ankara (Turkey); Middle Black Sea Passage Generation of Agricultural Research Station Director, Tokat (Turkey); Söylemezoğlu, Tülin [Ankara University, Institute of Forensic Sciences, Ankara (Turkey)

    2015-07-15

    Human hemochromatosis protein (HFE), a major histocompatibility complex class I-like integral membrane protein, participates in the down regulation of intestinal iron absorption by binding to transferrin receptor (TR). HFE competes with transferrin-bound iron for the TR and thus reduces uptake of iron into cells. On the other hand, a lack of HFE increases the intestinal absorption of iron similarly to iron deficiency associated with increasing in absorption and deposition of lead. During pregnancy, placenta cannot prevent transfer lead to the fetus; even low-level lead poisoning causes neurodevelopmental toxicity in children. The aim of this study was to determine the association between the maternal HFE H63D single-nucleotide polymorphism and lead levels in placental tissue, maternal blood and umbilical cord bloods. The study population comprised 93 mother–placenta pairs. Venous blood from mother was collected to investigate lead levels and HFE polymorphism that was detected by standard PCR–RFLP technique. Cord bloods and placentas were collected for lead levels which were analyzed by dual atomic absorption spectrometer system. The HFE H63D genotype frequencies of mothers were found as 75.3% homozygote typical (HH), 23.6% heterozygote (HD) and 1.1% homozygote atypical (DD). Our study results showed that the placental tissue, umbilical cord and maternal blood lead levels of mothers with HD+DD genotypes were significantly higher than those with HH genotype (p<0.05). The present study indicated for the first time that mothers with H63D gene variants have higher lead levels of their newborn's placentas and umbilical cord bloods. - Highlights: • Mothers with H63D gene variants have higher lead levels of their newborn's umbilical cord blood. • Unborn child of women with HD+DD genotypes may be at increased risk of internal exposure to lead. • Maternal HFE status may have an effect on increased placenta, maternal and cord blood lead levels.

  6. Maternal hemochromatosis gene H63D single-nucleotide polymorphism and lead levels of placental tissue, maternal and umbilical cord blood

    International Nuclear Information System (INIS)

    Kayaalti, Zeliha; Kaya-Akyüzlü, Dilek; Söylemez, Esma; Söylemezoğlu, Tülin

    2015-01-01

    Human hemochromatosis protein (HFE), a major histocompatibility complex class I-like integral membrane protein, participates in the down regulation of intestinal iron absorption by binding to transferrin receptor (TR). HFE competes with transferrin-bound iron for the TR and thus reduces uptake of iron into cells. On the other hand, a lack of HFE increases the intestinal absorption of iron similarly to iron deficiency associated with increasing in absorption and deposition of lead. During pregnancy, placenta cannot prevent transfer lead to the fetus; even low-level lead poisoning causes neurodevelopmental toxicity in children. The aim of this study was to determine the association between the maternal HFE H63D single-nucleotide polymorphism and lead levels in placental tissue, maternal blood and umbilical cord bloods. The study population comprised 93 mother–placenta pairs. Venous blood from mother was collected to investigate lead levels and HFE polymorphism that was detected by standard PCR–RFLP technique. Cord bloods and placentas were collected for lead levels which were analyzed by dual atomic absorption spectrometer system. The HFE H63D genotype frequencies of mothers were found as 75.3% homozygote typical (HH), 23.6% heterozygote (HD) and 1.1% homozygote atypical (DD). Our study results showed that the placental tissue, umbilical cord and maternal blood lead levels of mothers with HD+DD genotypes were significantly higher than those with HH genotype (p<0.05). The present study indicated for the first time that mothers with H63D gene variants have higher lead levels of their newborn's placentas and umbilical cord bloods. - Highlights: • Mothers with H63D gene variants have higher lead levels of their newborn's umbilical cord blood. • Unborn child of women with HD+DD genotypes may be at increased risk of internal exposure to lead. • Maternal HFE status may have an effect on increased placenta, maternal and cord blood lead levels.

  7. Religion, Education, and Secularism in International Agencies

    Science.gov (United States)

    Stambach, Amy; Marshall, Katherine; Nelson, Matthew J.; Andreescu, Liviu; Kwayu, Aikande C.; Wexler, Philip; Hotam, Yotam; Fischer, Shlomo; El Bilawi, Hassan

    2011-01-01

    During the interwar years of the early twentieth century, and through at least the 1980s, education was seen by scholars, state leaders, and international agency representatives alike as a way to modernize and secularize underdeveloped communities. Arguments about the modernizing power of education did not erase or discount the presence of…

  8. Lead exposure in the general population of the Metropolitan Area of Barcelona. Blood levels and related factors

    Energy Technology Data Exchange (ETDEWEB)

    Sole, E. [Pediatrics Service, Hospital Universitari Arnau de Vilanova, Lleida (Spain); Ballabriga, A.; Dominguez, C. [Centre d`Investigacions en Bioquimica y Biologia Molecular, Vall d`Hebron Hospitals, School of Medicine, Pediatrics Department, Universitat Autonoma de Barcelona, Barcelona (Spain)

    1998-12-11

    A cross-sectional was conducted on 254 individuals not occupationally exposed to lead to determine the degree of lead exposure in the general population of the Metropolitan Area of Barcelona. Blood lead levels (BPb) were analysed by atomic absorption spectrophotometry and zinc protoporphyrin (ZPP) by haemofluorimetry. Blood lead levels were analysed with respect to individuals` age, sex, area of residence, the season of the year the blood was drawn and ZPP. Mean blood lead in our series was 0.22{+-}0.011 {mu}mol/l (mean{+-}S.E.); no significant differences were found with respect to area of residence, sex or season. A linear relationship was observed between BPb and individuals` age (BPb=0.08+0.05xage; r=0.37). The prevalence of lead intoxication (BPb>0.48 {mu}mol/l) was 7.1%. No linear relationship was observed between BPb and ZPP. ZPP determination does not appear to be a good screening method for lead intoxication since it presents low specificity and sensitivity values with an area below the ROC curve similar to the null value line (area below the curve=0.5052, IC 95%=0.443-0.568). We conclude that lead exposure does not constitute a serious health problem in the area studied, since BPb levels found are far below the toxic limit and the prevalence of intoxication is similar to that reported in other studies conducted in other developed countries

  9. The conditions of believe and unbelieve in a secular Age

    Directory of Open Access Journals (Sweden)

    Juan Manuel Cincunegui

    2014-05-01

    Full Text Available In A Secular Age the Canadian philosopher Charles Taylor offered an analytical description and a genealogy of the current conditions of belief and unbelief in the North Atlantic contemporary societies. He encouraged as well a set of similar investigations in other cultural settings that are affected by the processes of modernization. He argues about the existence of ‘alternative modernities’ each one of them facing critically the univocal sociological theories of modernity and secularization that interpreted as universal the process of disenchantment occurred in the West and the setbacks with regard to the presence of religion in the public sphere and religious practice in some contemporary Western societies

  10. [Blood lead levels during pregnancy in th the newborn period. Study of the population of Bari].

    Science.gov (United States)

    Carbone, R; Laforgia, N; Crollo, E; Mautone, A; Iolascon, A

    1998-01-01

    Blood lead levels during pregnancy and in neonates immediately after birth have been evaluated, showing higher values in mothers compared to neonates (5.81 +/- 3.05 vs 4.87 +/- 3.60 micrograms/100 ml) and a positive correlation between maternal and neonatal levels (r = 0.82). On the basis of the results derived from the population examined, it has been observed that 6% of newborns have blood lead levels higher than 10 micrograms/100 ml a value recently identified by the Centers for Disease Control (CDC, Atlanta, USA) as a limit for toxicity in children. Moreover, neonatal Pb levels were higher than those found in infants from 6 to 12 months (4.87 +/- 3.60 vs 2.24 +/- 0.54 micrograms/100 ml). During the first week of life there is a steady decrease of blood lead levels, together with increasing renal lead excretion. This study was carried out at the "Dipartimento di Biomedicina dell'Età Evolutiva" University of Bari, southern Italy.

  11. Blood lead levels and associated factors among children in Guiyu of China: a population-based study.

    Science.gov (United States)

    Guo, Pi; Xu, Xijin; Huang, Binliang; Sun, Di; Zhang, Jian; Chen, Xiaojuan; Zhang, Qin; Huo, Xia; Hao, Yuantao

    2014-01-01

    Children's health problems caused by the electronic waste (e-waste) lead exposure in China remains. To assess children's blood lead levels (BLLs) in Guiyu of China and investigate risk factors of children's elevated BLLs in Guiyu. 842 children under 11 years of age from Guiyu and Haojiang were enrolled in this population-based study during 2011-2013. Participants completed a lifestyle and residential environment questionnaire and their physical growth indices were measured, and blood samples taken. Blood samples were tested to assess BLLs. Children's BLLs between the two groups were compared and factors associated with elevated BLLs among Guiyu children were analyzed by group Lasso logistic regression model. Children living in Guiyu had significant higher BLLs (7.06 µg/dL) than the quantity (5.89 µg/dL) of Haojiang children (Ppopulated areas as part of a comprehensive response to e-waste lead exposure control in Guiyu. To correct the problem of lead poisoning in children in Guiyu should be a long-term mission.

  12. Association of lead concentration in colostrum, maternal and cord blood with newborn weight in polluted vs. non-polluted areas of Iran

    Directory of Open Access Journals (Sweden)

    Golmohammadi T.

    2007-10-01

    Full Text Available Background: Lead poisoning has proven to be one of the most important environmental health problems among developing countries with both direct and indirect effects on human life. Lead is known to cross the blood-brain barrier and placenta, and accumulates in soft and hard tissues. Lead can be excreted in urine, stool, milk, sweat, nails and saliva. During pregnancy and lactation, lead is released from bones into the blood along with Ca2+. The toxic effects of lead on various human tissues have been studied extensively, but few studies have addressed its impact on fetal development during pregnancy. Blood levels of lead are higher in people living in lead-polluted regions. It has been reported that Tehran (central and southern parts is the most problematic city in terms of lead poisoning.Methods: From 86 sets of mothers and newborns in a non-polluted area of rural Rasht, Iran, we examined specimens of maternal blood, cord blood and colostrum (86×3=258 and specimens from 85 sets of mothers and newborns in a polluted area of Tehran, Iran (85×3=255 for lead levels using atomic absorption spectrophotometry (AAS and analyzed the results by t-test, SPSS, and linear regression.Results: The mean blood lead concentrations of mothers, cord blood of newborns and colostrum were 7.6±4.1, 5.9±3 and 4.2±2.5 μg/dl, respectively, in the non-polluted area and 9.1±8.4, 6.5±5.2 and 5.8±5.5 μg/dl, respectively, in the polluted area. The mean weights of the newborns in non-polluted and polluted areas were 3.2±0.5 kg and 3.2±4.5 kg, respectively.Conclusions: Our data revealed an association between mean concentrations in blood lead of mothers and newborns and between mean concentrations of colostrum lead and newborn blood lead in both areas (p=0.01. There was no association between mean blood lead concentration of mothers with the weight of their newborns (p=0.89.

  13. AN ORIGIN OF MULTIPLE RING STRUCTURE AND HIDDEN PLANETS IN HL TAU: A UNIFIED PICTURE BY SECULAR GRAVITATIONAL INSTABILITY

    International Nuclear Information System (INIS)

    Takahashi, Sanemichi Z.; Inutsuka, Shu-ichiro

    2016-01-01

    Recent ALMA observation has revealed multiple ring structures formed in a protoplanetary disk around HL Tau. Prior to the ALMA observation of HL Tau, theoretical analysis of secular gravitational instability (GI) described a possible formation of multiple ring structures with separations of 13 au around a radius of 100 au in protoplanetary disks under certain conditions. In this article, we reanalyze the viability of secular GI by adopting the physical values inferred from the observations. We derive the radial distributions of the most unstable wavelength and the growth timescale of secular GI and verify that secular GI can form the ring structures observed in HL Tau. When a turbulent viscosity coefficient α remains small in the inner region of the disk, secular GI grows in the whole disk. Thus, the formation of planetary mass objects should occur first in the inner region as a result of gravitational fragmentation after the nonlinear growth of secular GI. In this case, the resulting objects are expected to create gaps at r  ∼ 10 au and ∼30 au. As a result, all ring structures in HL Tau can be created by secular GI. If this scenario is realized in HL Tau, the outer region corresponds to the earlier growth phase of the most unstable mode of secular GI, and the inner region corresponds to the outcome of the nonlinear growth of secular GI. Therefore, this interpretation suggests that we are possibly witnessing both the beginning and the end of planet formation in HL Tau.

  14. AN ORIGIN OF MULTIPLE RING STRUCTURE AND HIDDEN PLANETS IN HL TAU: A UNIFIED PICTURE BY SECULAR GRAVITATIONAL INSTABILITY

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Sanemichi Z. [Astronomical Institute, Tohoku University, 6-3 Aoba, Aramaki-aza, Aoba-ku, Sendai, Miyagi (Japan); Inutsuka, Shu-ichiro, E-mail: sanemichi@astr.tohoku.ac.jp, E-mail: inutsuka@nagoya-u.jp [Department of Physics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-8602 (Japan)

    2016-12-01

    Recent ALMA observation has revealed multiple ring structures formed in a protoplanetary disk around HL Tau. Prior to the ALMA observation of HL Tau, theoretical analysis of secular gravitational instability (GI) described a possible formation of multiple ring structures with separations of 13 au around a radius of 100 au in protoplanetary disks under certain conditions. In this article, we reanalyze the viability of secular GI by adopting the physical values inferred from the observations. We derive the radial distributions of the most unstable wavelength and the growth timescale of secular GI and verify that secular GI can form the ring structures observed in HL Tau. When a turbulent viscosity coefficient α remains small in the inner region of the disk, secular GI grows in the whole disk. Thus, the formation of planetary mass objects should occur first in the inner region as a result of gravitational fragmentation after the nonlinear growth of secular GI. In this case, the resulting objects are expected to create gaps at r  ∼ 10 au and ∼30 au. As a result, all ring structures in HL Tau can be created by secular GI. If this scenario is realized in HL Tau, the outer region corresponds to the earlier growth phase of the most unstable mode of secular GI, and the inner region corresponds to the outcome of the nonlinear growth of secular GI. Therefore, this interpretation suggests that we are possibly witnessing both the beginning and the end of planet formation in HL Tau.

  15. "Doing the Secular": Academic Practices in the Study of Religion at Two Danish Universities

    Science.gov (United States)

    Johansen, Birgitte Schepelern

    2011-01-01

    The academic study of religion at the public university often presents itself as a secular, non-religious, scientific endeavor. The identity of the study is thus firmly rooted within one of the central secular-religious divides, namely that between science and religion. Based on the assumption that such distinctions between religion and the…

  16. Disparities in Children’s Blood Lead and Mercury Levels According to Community and Individual Socioeconomic Positions

    Science.gov (United States)

    Lim, Sinye; Ha, Mina; Hwang, Seung-Sik; Son, Mia; Kwon, Ho-Jang

    2015-01-01

    We aimed to examine the associations between blood lead and mercury levels and individual and community level socioeconomic positions (SEPs) in school-aged children. A longitudinal cohort study was performed in 33 elementary schools in 10 cities in Korea. Among a total of 6094 children included at baseline, the final study population, 2281 children followed-up biennially, were analyzed. The geometric mean (GM) levels of blood lead were 1.73 μg/dL (range 0.02–9.26) and 1.56 μg/dL (range 0.02–6.83) for male and female children, respectively. The blood lead levels were significantly higher in males, children living in rural areas, and those with lower individual SEP. The GM levels of blood mercury were 2.07 μg/L (range 0.09–12.67) and 2.06 μg/L (range 0.03–11.74) for males and females, respectively. Increased blood mercury levels were significantly associated with urban areas, higher individual SEP, and more deprived communities. The risk of high blood lead level was significantly higher for the lower individual SEP (odds ratio (OR) 2.18, 95% confidence interval (CI) 1.36–3.50 in the lowest educational attainment of the father), with a significant dose-response relationship observed after adjusting for the community SEP. The association between high blood lead levels and lower individual SEP was much stronger in the more deprived communities (OR 2.88, 95% CI 1.27–6.53) than in the less deprived communities (OR 1.40, 95% CI 0.76–2.59), and showed a significant decreasing trend during the follow-up only in the less deprived communities. The risk of high blood mercury levels was higher in higher individual SEP (OR 0.64, 95% CI 0.40–1.03 in the lowest educational attainment of the father), with a significant dose-response relationship noted. Significant decreasing trends were observed during the follow-up both in the less and more deprived communities. From a public health point-of-view, community level intervention with different approaches for

  17. Decreasing systolic blood pressure and declining mortality rates in an untreated population

    DEFF Research Database (Denmark)

    Andersen, Ulla O; Marott, Jacob L; Jensen, Gorm B

    2011-01-01

    The aim of the present study was to evaluate developments in 30 years mortality risk that may be associated with developments in population systolic blood pressure (SBP) and to evaluate possible secular trends in BP-associated mortality risk in the untreated population....

  18. Ethics of surrogacy: a comparative study of Western secular and islamic bioethics.

    Science.gov (United States)

    Islam, Sharmin; Nordin, Rusli Bin; Bin Shamsuddin, Ab Rani; Mohd Nor, Hanapi Bin; Al-Mahmood, Abu Kholdun

    2012-01-01

    The comparative approach regarding the ethics of surrogacy from the Western secular and Islamic bioethical view reveals both commensurable and incommensurable relationship. Both are eager to achieve the welfare of the mother, child and society as a whole but the approaches are not always the same. Islamic bioethics is straightforward in prohibiting surrogacy by highlighting the lineage problem and also other social chaos and anarchy. Western secular bioethics is relative and mostly follows a utilitarian approach.

  19. Ethics of Surrogacy: A Comparative Study of Western Secular and Islamic Bioethics

    Science.gov (United States)

    Islam, Sharmin; Nordin, Rusli Bin; Bin Shamsuddin, Ab Rani; Mohd Nor, Hanapi Bin; Al-Mahmood, Abu Kholdun

    2012-01-01

    The comparative approach regarding the ethics of surrogacy from the Western secular and Islamic bioethical view reveals both commensurable and incommensurable relationship. Both are eager to achieve the welfare of the mother, child and society as a whole but the approaches are not always the same. Islamic bioethics is straightforward in prohibiting surrogacy by highlighting the lineage problem and also other social chaos and anarchy. Western secular bioethics is relative and mostly follows a utilitarian approach. PMID:23864994

  20. Lead concentration in blood of school children from copper mining area and the level of somatic development at birth

    Directory of Open Access Journals (Sweden)

    Teresa Sławińska-Ochla

    2011-12-01

    Full Text Available Background. The aim of the study was to assess the relations between lead intoxication in children at younger school age and the level of somatic development at birth. Materials and Methods. The research includes 717 children and adolescents 7–15 years old from LegnickoGłogowski copper mining region, which live in the vincity of „Głogów”, „Legnica” copper industrial plants and flotation tank reservoir „Żelazny most”. The analysis contained measures such as birth height, birth weight, Apgar score points, and blood lead level in 2007 and 2008. The whole blood lead level (Pb-B was indicated using atomic absorption spectrometry (AAS with electrothermic atomization by certified The Foundation for Children From The Copper Basin laboratory. Results.Rural childrenwere noted forsignificantly higher blood lead levelsthan urban peers. Also boysin comparison to girls had higher blood lead levels. Regardless of gender and place of residence there were no significant correlation between blood lead level and body mass at birth. Conclusion. The biological state of the organism at the moment of birth has no connection with the susceptibility to absorption of lead in the later phases of ontogenesis: the earlier school age and adlescence.

  1. Application of proton-induced X-ray emission method to determination of lead content in blood

    International Nuclear Information System (INIS)

    Slominska, D.; Jarczyk, L.; Rokita, E.; Strzalkowski, A.; Losiowski, A.; Macheta, A.; Sych, M.; Moszkowicz, S.

    1979-01-01

    The proton induced X-ray emission method is applied for determination of lead content in the blood of the people exposed to contact with ethyline vapours and people working in lead-zinc works. (author)

  2. Blood lead exposure concentrations in mottled ducks (Anas fulvigula) on the upper Texas coast

    Science.gov (United States)

    McDowell, Stephen K.; Conway, Warren C.; Haukos, David A.; Moon, Jena A.; Comer, Christopher E.; Hung, I-Kuai

    2015-01-01

    The mottled duck (Anas fulvigula) is a non-migratory waterfowl species dependent upon coastal marsh systems, including those on the Texas Chenier Plain National Wildlife Refuge (NWR) Complex, and considered a regional indicator species of marsh habitat quality. Research from the early 1970s, 1990s, and early-2000s indicated that mottled ducks continued to exhibit elevated wing-bone lead (Pb) concentrations, decades after implementation of non-toxic shot regulations. However, wing-bone concentrations reflect lifetime accumulation of Pb, whereas blood Pb concentrations reflect more recent exposure. To identify current potentially relevant temporal windows of Pb exposure, we collected 260 blood samples from mottled ducks during summer (n=124) and winter (n=136) from 2010–2012 on the Texas Chenier Plain NWR Complex. We quantified baseline blood Pb concentrations for all ages of mottled ducks, and hypothesized that blood lead concentrations would remain elevated above background levels (200 µg L–1) despite the 1983 and 1991 lead shot bans. Blood Pb concentrations ranged from below detection limits to >12,000 µg L–1, where >200 µg L–1 was associated with exposure levels above background concentrations. Male mottled ducks had the greatest blood Pb concentrations (30 times greater than females) with concentrations greater during winter than summer. Likewise, the proportion of exposed (>200 µg L–1) females increased from 14%–47% from summer to winter, respectively. Regardless of sex, adult mottled duck blood Pb concentrations were five times greater than juveniles, particularly during winter. We identified five plausible models that influenced blood Pb levels where year, site, and interactions among age*sex*season and between age*season were included in the top-ranked models. Frequency of exposure was greatest during winter, increasing from 12% in summer to 55% in winter, indicating that a temporal exposure window to environmental Pb exists between nesting

  3. Sacred Spaces: Religious and Secular Coping and Family Relationships in the Neonatal Intensive Care Unit.

    Science.gov (United States)

    Brelsford, Gina M; Ramirez, Joshua; Veneman, Kristin; Doheny, Kim K

    2016-08-01

    Preterm birth is an unanticipated and stressful event for parents. In addition, the unfamiliar setting of the intensive care nursery necessitates strategies for coping. The primary study objective of this descriptive study was to determine whether secular and religious coping strategies were related to family functioning in the neonatal intensive care unit. Fifty-two parents of preterm (25-35 weeks' gestation) infants completed the Brief COPE (secular coping), the Brief RCOPE (religious coping), and the Family Environment Scale within 1 week of their infant's hospital admission. This descriptive study found that parents' religious and secular coping was significant in relation to family relationship functioning. Specifically, negative religious coping (ie, feeling abandoned or angry at God) was related to poorer family cohesion and use of denial. These findings have relevance for interventions focused toward enhancing effective coping for families. Further study of religious and secular coping strategies for neonatal intensive care unit families is warranted in a larger more diverse sample of family members.

  4. Blood Lead Concentrations in 1–3 Year Old Lebanese Children: A Cross-sectional study

    Directory of Open Access Journals (Sweden)

    Salem George

    2003-04-01

    Full Text Available Abstract Background Childhood lead poisoning has not made the list of national public health priorities in Lebanon. This study aims at identifying the prevalence and risk factors for elevated blood lead concentrations (B-Pb ≥ 100 μg/L among 1–3 year old children. It also examines the need for universal blood lead screening. Methods This is a cross-sectional study of 281 well children, presenting to the pediatric ambulatory services at the American University of Beirut Medical Center in 1997–98. Blood was drawn on participating children for lead analysis and a structured questionnaire was introduced to mothers asking about social, demographic, and residence characteristics, as well as potential risk factors for lead exposure. Children with B-Pb ≥ 100 μg/L were compared to those with B-Pb Results Mean B-Pb was 66.0 μg/L (median 60.0; range 10–160; standard deviation 26.3 with 39 (14% children with B-Pb ≥ 100 μg/L. Logistic regression analysis showed that elevated B-Pb was associated with paternal manual jobs (odds ratio [OR]: 4.74, residence being located in high traffic areas (OR: 4.59, summer season (OR: 4.39, using hot tap water for cooking (OR: 3.96, exposure to kohl (OR: 2.40, and living in older buildings (OR: 2.01. Conclusion Lead screening should be offered to high-risk children. With the recent ban of leaded gasoline in Lebanon, emphasis should shift to other sources of exposure in children.

  5. Blood Lead Concentrations in 1–3 Year Old Lebanese Children: A Cross-sectional study

    Science.gov (United States)

    Nuwayhid, Iman; Nabulsi, Mona; Muwakkit, Samar; Kouzi, Sarah; Salem, George; Mikati, Mohamed; Ariss, Majd

    2003-01-01

    Background Childhood lead poisoning has not made the list of national public health priorities in Lebanon. This study aims at identifying the prevalence and risk factors for elevated blood lead concentrations (B-Pb ≥ 100 μg/L) among 1–3 year old children. It also examines the need for universal blood lead screening. Methods This is a cross-sectional study of 281 well children, presenting to the pediatric ambulatory services at the American University of Beirut Medical Center in 1997–98. Blood was drawn on participating children for lead analysis and a structured questionnaire was introduced to mothers asking about social, demographic, and residence characteristics, as well as potential risk factors for lead exposure. Children with B-Pb ≥ 100 μg/L were compared to those with B-Pb < 100 μg/L. Results Mean B-Pb was 66.0 μg/L (median 60.0; range 10–160; standard deviation 26.3) with 39 (14%) children with B-Pb ≥ 100 μg/L. Logistic regression analysis showed that elevated B-Pb was associated with paternal manual jobs (odds ratio [OR]: 4.74), residence being located in high traffic areas (OR: 4.59), summer season (OR: 4.39), using hot tap water for cooking (OR: 3.96), exposure to kohl (OR: 2.40), and living in older buildings (OR: 2.01). Conclusion Lead screening should be offered to high-risk children. With the recent ban of leaded gasoline in Lebanon, emphasis should shift to other sources of exposure in children. PMID:12780938

  6. Biomonitoring of Lead, Cadmium, Total Mercury, and Methylmercury Levels in Maternal Blood and in Umbilical Cord Blood at Birth in South Korea

    Science.gov (United States)

    Kim, Yu-Mi; Chung, Jin-Young; An, Hyun Sook; Park, Sung Yong; Kim, Byoung-Gwon; Bae, Jong Woon; Han, Myoungseok; Cho, Yeon Jean; Hong, Young-Seoub

    2015-01-01

    With rising concerns of heavy metal exposure in pregnancy and early childhood, this study was conducted to assess the relationship between the lead, cadmium, mercury, and methylmercury blood levels in pregnancy and neonatal period. The study population included 104 mothers and their children pairs who completed both baseline maternal blood sampling at the second trimester and umbilical cord blood sampling at birth. The geometric mean maternal blood levels of lead, cadmium, total mercury, and methylmercury at the second trimester were 1.02 ± 1.39 µg/dL, 0.61 ± 1.51 µg/L, 2.97 ± 1.45 µg/L, and 2.39 ± 1.45 µg/L, respectively, and in the newborns, these levels at birth were 0.71 ± 1.42 µg/dL, 0.01 ± 5.31 µg/L, 4.44 ± 1.49 µg/L, and 3.67 ± 1.51 µg/L, respectively. The mean ratios of lead, cadmium, total mercury, and methylmercury levels in the newborns to those in the mothers were 0.72, 0.04, 1.76, and 1.81, respectively. The levels of most heavy metals in pregnant women and infants were higher in this study than in studies from industrialized western countries. The placenta appears to protect fetuses from cadmium; however, total mercury and methylmercury were able to cross the placenta and accumulate in fetuses. PMID:26516876

  7. Childhood lead poisoning data for California by county, age, and blood lead level for the years 2007-2009; and age of housing data for 2000.

    Data.gov (United States)

    California Environmental Health Tracking Program — This dataset contains counts and percentages of blood lead levels among children tested for lead poisoning during 2007-2009 within California . The data are...

  8. Effects of blood lead and cadmium levels on the functioning of children with behaviour disorders in the family environment.

    Science.gov (United States)

    Szkup-Jabłońska, Małgorzata; Karakiewicz, Beata; Grochans, Elżbieta; Jurczak, Anna; Nowak-Starz, Grażyna; Rotter, Iwona; Prokopowicz, Adam

    2012-01-01

    The developing brain of a child is extremely prone to damage resulting from exposure to harmful environmental factors, e.g. heavy metals. Intoxication of children's organisms with lead and cadmium affects their intellectual development. Even a relatively small amount of this metal in children's blood can lead to developmental dysfunctions. The aim of this study was to analyse the correlation between blood lead and cadmium levels in children with behaviour disorders and their functioning in the home. This survey-based study was conducted among 78 families with children diagnosed as having behaviour disorders. It was performed using the ADHD-Rating Scale-IV. To determine lead and cadmium levels the laboratory procedure was based on Stoppler and Brandt's method. The mean blood lead level was 19.71 µg/l and the mean blood cadmium level was 0.215 µg/l. Higher blood lead levels in children correlates positively with incidences of hyperactive and impulsive behaviour in the home, as assessed by parents (p=0.048). Statistically significant effects of cadmium on children's behaviour were not noticed. The effect of lead on the developing organism of a child has such behavioural consequences as attention disorders, hyperactivity and impulsive behaviour which, in turn, may interfere with children's functioning in the home. A negative effect of cadmium on the functioning of children with behaviour disorders in the home was not proved.

  9. Internal and environmental secular evolution of disk galaxies

    Science.gov (United States)

    Kormendy, John

    2015-03-01

    This Special Session is devoted to the secular evolution of disk galaxies. Here `secular' means `slow' i.e., evolution on time scales that are generally much longer than the galaxy crossing or rotation time. Internal and environmentally driven evolution both are covered. I am indebted to Albert Bosma for reminding me at the 2011 Canary Islands Winter School on Secular Evolution that our subject first appeared in print in a comment made by Ivan King (1977) in his introductory talk at the Yale University meeting on The Evolution of Galaxies and Stellar Populations: `John Kormendy would like us to consider the possibility that a galaxy can interact with itself.. . . I'm not at all convinced, but John can show you some interesting pictures.' Two of the earliest papers that followed were Kormendy (1979a, b); the first discusses the interaction of galaxy components with each other, and the second studies these phenomena in the context of a morphological survey of barred galaxies. The earliest modeling paper that we still use regularly is Combes & Sanders (1981), which introduces the now well known idea that box-shaped bulges in edge-on galaxies are side-on, vertically thickened bars. It is gratifying to see how this subject has grown since that time. Hundreds of papers have been written, and the topic features prominently at many meetings (e.g., Block et al. 2004; Falcoń-Barroso & Knapen 2012, and this Special Session). My talk here introduces both internal and environmental secular evolution; a brief abstract follows. My Canary Islands Winter School review covers both subjects in more detail (Kormendy 2012). Kormendy & Kennicutt (2004) is a comprehensive review of internal secular evolution, and Kormendy & Bender (2012) covers environmental evolution. Both of these subject make significant progress at this meeting. Secular evolution happens because self-gravitating systems evolve toward the most tightly bound configuration that is reachable by the evolution processes

  10. Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys

    DEFF Research Database (Denmark)

    Andersson, Anna-Maria; Jensen, Tina Kold; Juul, Anders

    2007-01-01

    Adverse secular trends in male reproductive health have been reported to be reflected in increased testicular cancer risk and decreased semen quality in more recently born men. These secular trends may also be reflected by changes in Leydig cell function....

  11. Blood Concentrations of Cadmium and Lead in Multiple Sclerosis Patients from Iran.

    Science.gov (United States)

    Aliomrani, Mehdi; Sahraian, Mohammad Ali; Shirkhanloo, Hamid; Sharifzadeh, Mohammad; Khoshayand, Mohammad Reza; Ghahremani, Mohammad Hossein

    2016-01-01

    Since industrial revolution heavy metals such as lead (Pb) and cadmium (Cd) have been extensively dispersed in environment which, unknown biological effects and prolong biological half-life make them as a major hazard to human health. In addition, the sharp increase in Multiple sclerosis incidence rateshas been recorded in Iran. The propose of this study was to measuring blood lead and cadmium concentration and their correlation with smoking habit in a group of 69 RRMS patients and 74 age/gender-matched healthy individuals resident in Tehran as most polluted city in Iran. All subjects were interviewed regarding age, medical history, possible chemical exposure, acute or chronic diseases, smoking and dietary habits. Blood Pb and Cd levels were measured by double beam GBC plus 932 atomic absorption spectrometer. Our result indicated a significant difference in Cd level (p = 0.006) in which, MS patients had higher blood concentration (1.82 ± 0.13 μg/L) in comparison with healthy individuals (1.47 ± 0.11 μg/L). A comparable blood Cd level to similar recent study (1.78 µg/L vs.1.82 µg/L) was observed. With respect to Pb there was no significant difference between cases and controls, however the geometric means of blood Pb concentration were considerably higher in males than in females in MS patients (57.1 ± 33.7 μg/L vs . 36.7 ± 21.9 μg/L. P = 0.02). Taking into consideration tobacco smoking, an elevated contents of each metal were observed in smoker subjects (p<0.0001). A significant correlation between cigarette smoking and risk of multiple sclerosis was shown before. Thus, high level of Cd in smokers might affect the susceptibility to multiple sclerosis and could increase the risk of disease development.

  12. Contrasting effects of age on the plasma/whole blood lead ratio in men and women with a history of lead exposure

    International Nuclear Information System (INIS)

    Barbosa, Fernando; Ramires, Irene; Rodrigues, Maria Heloisa C.; Saint' Pierre, Tatiana D.; Curtius, Adilson J.; Buzalaf, Marilia R.; Gerlach, Raquel F.; Tanus-Santos, Jose E.

    2006-01-01

    We examined the effect of age and sex on the relationship between the concentrations of Pb in blood (Pb-B) and in plasma (Pb-P) in an adult population with a history of lead exposure. Pb-P was determined by inductively coupled plasma mass spectrometry (ICP-MS) and Pb-B by graphite furnace atomic absorption spectrometry (GF AAS). We studied 154 adults (56 men and 98 women) from 18 to 60-year old. Pb-B levels varied from 10.0 to 428.0 μg/L, with a mean of 76 μg/L. Blood lead levels varied from 10.0 to 428.0 μg/L in men (mean, 98.3 μg/L) and from 10.0 to 263.0 μg/L (mean, 62.8 μg/L) in women. Corresponding Pb-Ps were 0.02-2.9 μg/L (mean, 0.66 μg/L) and 0.02-1.5 μg/L (mean, 0.42 μg/L) in men and women, respectively. The relationship between Pb-B and Pb-P was found to be curvilinear (r=0.757, P 1492 (y=Pb-P, and x=Pb-B). The %Pb-P/Pb-B ratio ranged from 0.03% to 1.85%. A positive association was found between %Pb-P/Pb-B ratio and Pb-B levels. When data were separated by sex, this association was also relevant for men (y=0.0184x 0.702 ) and women (y=0.0534x 0.5209 ) (y=%Pb-P/Pb-B and x=Pb-B). Moreover, we found an interesting positive correlation between Log (Pb-P/Pb-B) and age for women (r=0.31, P<0.0001) and a negative correlation for men (r=-0.164, P=0.07). Taken together, these results suggest contrasting effects of age on the plasma/whole blood lead ratio in men and women with a history of lead exposure. Moreover, sex might play an important role in the metabolism of lead, implying further consideration on the kinetic models constructed of lead toxicity

  13. Biomonitoring of lead-contaminated Missouri streams with an assay for erythrocyte δ-aminolevulinic acid dehydratase activity in fish blood

    Science.gov (United States)

    Schmitt, C.J.; Wildhaber, M.L.; Hunn, J.B.; Nash, T.; Tieger, M. N.; Steadman, B. L.

    1993-01-01

    The activity of the enzyme δ-aminolevulinic acid dehydratase (ALA-D) in erythrocytes has long been used as a biomarker of lead exposure in humans and waterfowl and, more recently, in fishes. The assay was tested for ALA-D activity in fishes from streams affected by lead in combination with other metals from lead-zinc mining and related activities. Fishes (mostly catostomids) were collected from sites affected by historic and current mining activities, and from sites considered to be unaffected by mining (reference sites). A group of potentially toxic elements was measured in blood and carcass samples of individual fish, as were ALA-D activity, total protein (TP), and hemoglobin (Hb) in blood. Concentrations of mining-related metals (lead, zinc, and cadmium) were significantly greater (P<0.05) in fish blood and carcass at sites affected by historic mining activities than at reference and active mining sites. When analyzed by multiple regression, ALA-D activity, Hb, and TP accounted for 66% of blood-lead and 69% of carcass-lead variability. Differences among species were small. ALA-D activity as a biomarker adequately distinguished sites affected by bioavailable environmental lead. Zinc was the only other metal that affected ALA-D activity; it appeared to ameliorate the inactivation of ALA-D by lead.

  14. Evidence in the auroral record for secular solar variability

    International Nuclear Information System (INIS)

    Sicoe, G.L.

    1980-01-01

    The historial record of aurorae is continuous and usefully dense for at least the 2000 years. Revival of interest in the secular variability in solar activity motivates a review of the auroral record. The existence of secular variations in the auroral occurrence frequency has been known since the early 1700's, including the existence of a significant attenuation of auroral activity during the Maunder Minimum. Investigation of secular variations prior to the Maunder Minimum is now possible based on six auroral catalogs that have been published within the last 20 years. The catalogs cover the time period from the fifth century B.C. to the seventeenth century A.D. and combine both oriental and European obsertions. Features corresponding to the previously recognized Medieval Minimum, Medieval Maximum, and the Spoerer Minimum are clearly evident in both oriental and European records. The global synchronicity of anomalies in the auroral occurrence frequency is used to argue that they are caused by changes in the level or state of solar activity. The combined catalogs provide a sufficient number of events in the Middle Ages to resolve a quasi-80-year periodicity in the recorded auroral occurrence frequency. Also in the unusually rich intervals of the Middle Ages, clear quasi-10-year periodicities appear in the recorded occurrence frequency wave from. These are most reasonably interpreted as manifestations of the 11-year solar cycle and indicate that the solar cycle was then operative

  15. An instance of secularization? The Finnish online discussion of the issue of same-sex marriages

    Directory of Open Access Journals (Sweden)

    Jenni Hokka

    2013-01-01

    Full Text Available In October 2010 one of Finland’s four national TV channels aired a panel discussion dealing with gay and lesbian rights in society. Among the debaters were members of parliament from various parties, well-known actors and other public figures, as well as a priest, a bishop and other religious spokespeople. Afterwards, a great number of people publicly expressed their views on same-sex marriages. The ways the Lutheran Church treated the same-sex couples, as well as the reasons and outcomes of a vast number of resignations from the Church were discussed, particularly in the online discussion forums. The public discussion spread rapidly, especially through the social media. Resignations from the Church are often perceived as a clear sign of the decline of religious beliefs and practices, which is an integral aspect of the secularization process. But lately the whole notion of a secularization of society has been questioned and a growing number of researchers have stated that the concepts of resacralization, desecularization, or a resurgence of religion would actually better describe the current situation than the theory of secularization. The aim of this article is to examine whether the concept of secularization still has some explanatory power at least in the Nordic countries. Another aim is to contemplate what kind of knowledge this special case has to offer when rethinking secularization.

  16. Kosovar Society through Secularism and Religion

    OpenAIRE

    MSc. Dritero Arifi; Dr.Sc. Ylber Sela

    2013-01-01

    This paper will analyze the importance and the effects of religion, in Kosovar society. A great part of the paper, will analyze the social and the political relations in Post-War Kosovo. Initially it will elaborate religion and secularism, especially in theoreticall aspect, what impact have these definitions in modern societies. In order to explain what the importance of the religion in Kosovo is, we will focus on analyzing ethnical, social and political relations within Kosovo society. A...

  17. Proper Elements and Secular Resonances for Irregular Satellites

    Science.gov (United States)

    Beaugé, C.; Nesvorný, D.

    2007-06-01

    We present results of an analytical study of proper elements and secular resonances for the irregular satellites of the outer planets. In the case of the Jovian system we identify three satellite families, two of them previously known (Carme and Ananke), plus a new agglomeration of four bodies that includes Pasiphae as its largest member. While the distribution of proper elements for Saturn's moons seems to be more random, a small cluster was found for the direct moons formed by Albiorix, Erriapo, and 2004 S1, slightly different from the so-called Gaulish cluster. No significant families are detected in the present study for the Uranian or Neptunian satellite systems. For each satellite system we determine the location of several secular resonances in the proper element space. Apart from the well-known resonance locks of Pasiphae, Sinope, and Siarnaq, a comparison between the resonance locations and proper elements shows that Saturn's satellite Narvi also exhibits temporary librations in the ϖ-ϖsolar resonance. However, unlike the resonant Jovian moons that are located in the same configuration, Narvi's critical argument librates alternately around values near 90° and 270°. Neither the Uranian nor Neptunian systems seem to have resonant moons. The resonant dynamics of the real satellites in the vicinity of ϖ˙-ϖ˙solar=0 is studied with a simple model for secular resonances based on the restricted three-body problem. Depending on the initial conditions, we show the existence of one or two modes of libration that can occur at different values of the critical angle, showing a good correspondence with the observed behavior of all the resonant moons. Finally, we discuss the global distribution of the real satellites with respect to the secular resonances, as compared with synthetic populations of bodies drawn solely from stability conditions. For Saturn, we find that the present satellite population appears compatible with simple random distributions. Although

  18. Reference intervals of cadmium, lead, and mercury in blood, urine, hair, and nails among residents in Mansoura city, Nile Delta, Egypt

    International Nuclear Information System (INIS)

    Mortada, Waelin I.; Sobh, Mohamed A.; El-Defrawy, Mohamed M.; Farahat, Sami E.

    2002-01-01

    A random sample of 68 males and 25 females who reside in Mansoura city, Egypt, was examined for concentrations of cadmium, lead, and mercury in blood, urine, hair, and nails. The effect of gender and smoking on such levels was studied. The influence of dental amalgam on the levels of mercury in these biological samples were also examined. The results obtained show that only blood lead, which increased among males, was affected by gender. Blood levels of cadmium and lead as well as hair lead appeared to increase with smoking habit. Mercury levels in blood and urine were related to the presence of dental amalgam fillings. International comparisons between our results and the corresponding levels in other localities in the world showed that there ere environmentally related variations in terms of cadmium levels in hair, lead levels in blood, urine, hair, and nails, and mercury levels in blood, air, and nails. In conclusion, reference intervals of cadmium, lead, and mercury in the biological samples are environmentally related parameters. Some factors, such as gender, smoking habit, and the presence of dental amalgam fillings, may affect such levels and therefore should be considered

  19. Religiousness and religious coping in a secular society: the gender perspective.

    Science.gov (United States)

    Hvidtjørn, Dorte; Hjelmborg, Jacob; Skytthe, Axel; Christensen, Kaare; Hvidt, Niels Christian

    2014-10-01

    Women are found to be more religious than men and more likely to use religious coping. Only few studies have explored religious gender differences in more secular societies. This population-based study comprised 3,000 Danish men and women (response rate 45 %) between 20 and 40 years of age. Information about demographics, religiousness and religious coping was obtained through a web-based questionnaire. We organized religiousness in the three dimensions: Cognition, Practice and Importance, and we assessed religious coping using the brief RCOPE questionnaire. We found substantial gender differences in both religiousness and religious coping. Nearly, 60 % of the women believed in some sort of spirit or in God compared to 40 % of the men. Generally, both men and women scored low on the RCOPE scale. However, for respondents reporting high levels of religiousness, the proportion of men who scored high in the RCOPE exceeded the proportion of women in using positive and especially negative coping strategies. Also, in a secular society, women are found to be more religious than men, but in a subset of the most religious respondents, men were more inclined to use religious coping. Further studies on religious coping in secular societies are required.

  20. Blood lead concentration and related factors in Korea from the 2008 National Survey for Environmental Pollutants in the Human Body.

    Science.gov (United States)

    Jeong, Seong Wook; Lee, Chae Kwan; Suh, Chun Hui; Kim, Kun Hyung; Son, Byung Chul; Kim, Jeong Ho; Lee, Jong Tae; Lee, Soo Woong; Park, Yeong Beom; Lee, Jong Wha; Yu, Seung-Do; Moon, Chan Seok; Kim, Dae Hwan; Lee, Sang Yoon

    2014-11-01

    This study evaluated blood lead concentrations in the Korean general population and the correlation between various exposure sources using data from the 2008 Korea National Survey for Environmental Pollutants in the Human Body (National Institute of Environmental Research, Korea). The general and occupational characteristics were gathered from 5136 participants who were 20 years of age and older using a structured questionnaire. Blood lead concentrations were analyzed using an atomic absorption spectrophotometer. Statistical analysis was performed using multiple linear regressions of the log lead concentrations to the independent variables such as age, gender, smoke, herbal medication and drug consumption, drinking water, and living area. Geometric mean (GM) blood lead concentrations in Korean adults were 19.7 μg/l. The blood lead concentrations increased with age; the highest concentrations were found in the 50-69-year age group (pdrug consumption were higher than those who did not (plead concentration (plead concentration (plead concentration, but not significantly. For drinking water, the underground water (spring or well water) drinking group had higher concentrations than other types of water drinking groups, but not significantly (p=0.063). The blood lead concentrations by occupation were significant (plead concentrations tended to decrease with increasing delivery times, but not significantly. The blood lead concentration (GM) of the general adult population in Korea has decreased over time from 45.8 μg/l (1999) to 19.7 μg/l (2008). Although it is still higher than in other countries such as the United States and Canada, it is rapidly decreasing. Gender, age, smoking and alcohol drinking status, herbal medication and drug consumption, education level, living area and occupation were significantly related to the blood lead concentrations in Korea. Copyright © 2014. Published by Elsevier GmbH.

  1. SPIRITUALITY IN A SECULAR AGE: FROM CHARLES TAYLOR TO ...

    African Journals Online (AJOL)

    the secular is ignored or where exclusive humanism is seen as the inevitable conclusion of a .... responsible for ordinary events in the world. Various .... immanent frame is dependent on and open to a transcendent source while for others, the ...

  2. Determination of lead and zinc concentrations in the blood and liver of the captive common green iguana (Iguana iguana).

    Science.gov (United States)

    Burns, Russell P; Paul-Murphy, Joanne

    2009-09-01

    Heavy metal toxicosis is a well-known phenomenon in wild, captive-animal, and domestic animal medicine. However, the occurrence among reptiles is not well documented. One reason for this is the lack of information regarding reference blood and tissue levels of heavy metals in reptiles. To determine normal blood lead, plasma zinc, and liver lead and zinc concentrations, blood and liver samples were collected from 4 adult and 16 juvenile, healthy green iguanas (Iguana iguana). Lead and zinc levels were measured using atomic absorption spectroscopy. Using the mean +/- two SD as the normal reference range, the present study suggests the following for captive common green iguana: 1) whole blood lead level: 0.06 +/- 0.06 microg/ml; 2) plasma zinc level: 2.68 +/- 1.66 microg/ml; 3) liver lead level (wet-weight basis): <1.0 +/- 0.0 microg/g; 4) liver lead level (dry-weight basis): <3.0 +/- 0.0 microg/g; 5) liver zinc level (wet-weight basis): 24.9 +/- 11.6 microg/g; and 6) liver zinc level (dry-weight basis): 83.4 +/- 44.6 microg/g. These values are fairly consistent with published reference levels in other mammalian and avian species.

  3. Blood coagulation in lead poisoning and the influence of specific treatment

    Energy Technology Data Exchange (ETDEWEB)

    Levantovskaya, O M; Lyubcenko, P N; Dayhin, I S; Sorkina, N S

    1974-07-01

    Results of blood coagulation studies in 104 workers with long-term exposure in a storage-battery plant. Over-all coagulation activity is unchanged in cases of mild lead poisoning, but long-term exposure gives rise to increased fibrinogen levels, activated fibrinolysis, and reduced serum accelerator globulin and prothrombin activities. 13 workers were given D-penicillamine (oral doses of 450 mg daily). All coagulation indices had become normal after 10 days' treatment. The changes observed are thought to be due to protein synthesis disturbances in the liver and to inhibition of enzymes by lead which combines with their sulfhydryl and disulfide groups. (CIS Abstr. Vol. 2)

  4. The influence of declining air lead levels on blood lead-air lead slope factors in children.

    Science.gov (United States)

    Richmond-Bryant, Jennifer; Meng, Qingyu; Davis, Allen; Cohen, Jonathan; Lu, Shou-En; Svendsgaard, David; Brown, James S; Tuttle, Lauren; Hubbard, Heidi; Rice, Joann; Kirrane, Ellen; Vinikoor-Imler, Lisa C; Kotchmar, Dennis; Hines, Erin P; Ross, Mary

    2014-07-01

    It is difficult to discern the proportion of blood lead (PbB) attributable to ambient air lead (PbA), given the multitude of lead (Pb) sources and pathways of exposure. The PbB-PbA relationship has previously been evaluated across populations. This relationship was a central consideration in the 2008 review of the Pb national ambient air quality standards. The objectives of this study were to evaluate the relationship between PbB and PbA concentrations among children nationwide for recent years and to compare the relationship with those obtained from other studies in the literature. We merged participant-level data for PbB from the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) and NHANES 9908 (1999-2008) with PbA data from the U.S. Environmental Protection Agency. We applied mixed-effects models, and we computed slope factor, d[PbB]/d[PbA] or the change in PbB per unit change in PbA, from the model results to assess the relationship between PbB and PbA. Comparing the NHANES regression results with those from the literature shows that slope factor increased with decreasing PbA among children 0-11 years of age. These findings suggest that a larger relative public health benefit may be derived among children from decreases in PbA at low PbA exposures. Simultaneous declines in Pb from other sources, changes in PbA sampling uncertainties over time largely related to changes in the size distribution of Pb-bearing particulate matter, and limitations regarding sampling size and exposure error may contribute to the variability in slope factor observed across peer-reviewed studies.

  5. PEDIATRIC FITNESS: SECULAR TRENDS AND GEOGRAPHIC VARIABILITY

    Directory of Open Access Journals (Sweden)

    Grant R. Tomkinson

    2007-06-01

    Full Text Available DESCRIPTION This book describes and discusses children's physical capacity in terms of aerobic and anaerobic power generation according to secular trends and geographic variability. PURPOSE To discuss the controversial issue of whether present day's children and adolescents are fitter than their equals of the past and whether they are fitter if they live in the more prosperous countries. AUDIENCE Pediatricians, medical practitioners, physical educators, exercise and/or sport scientists, exercise physiologists, personal trainers and graduate students in relevant fields will find this book helpful when dealing with contemporary trends and geographic variability in pediatric fitness. FEATURES The volume starts by examining the general picture on children fitness by the editors. The individual chapter's authors discuses the data gathered since the late 1950s on secular trends and geographic changeability in aerobic and anaerobic pediatric fitness performances of children and adolescents from 23 countries in Africa, Asia, Australasia, Europe, the Middle East and North America. There are chapters proposing that there is proof that there has been a world-wide decline in pediatric aerobic performance in recent decades, relative stability in anaerobic performance, and that the best performing children come from northern and central Europe. In final chapters possible causes to that end are considered, including whether weakening in aerobic performance are the result of distributional or widespread declines, and whether increases in obesity alone can explain the failure in aerobic performance. ASSESSMENT The editors have assembled a volume of Medicine and Sports Science that is necessary and essential reading for all who are interested in understanding and improving the fitness of children. The readers will find useful information in this book on secular trends and geographic variability in pediatric fitness. I believe, the book will serve as a first

  6. The Problems of Teaching the Basics of Secular Ethics to Pedagogic Students

    Directory of Open Access Journals (Sweden)

    L. V. Shcheglova

    2013-01-01

    Full Text Available The paper looks at the specialists training for teaching the Basics of Secular Ethics course in the secondary school. In author’s opinion, the above course is entitled to develop children’s moral consciousness. The subject is practical rather than descriptive, focused on the spiritual work, and teaching how to live in harmony with themselves and the surrounding world. The author emphasizes the difference between the secular and religious ethics related to the specificity of moral consciousness - based either on the principle of personal moral autonomy or theonomy in case of the religious ethics. The problematic task of developing the morally independent personality in the modern society is complicated by the confusion of ethics and etiquette, wide spread ideas of pluralism, relativism, infantilism and sense gratification. The challenges and inner contradictions of the given educational module are revealed in dealing with such concepts as the mercy and moral ideal. In conclusion, the author points out the significance of active positions of teachers and students alike in pursuing the Secular Ethics course. 

  7. Crustal concealing of small-scale core-field secular variation

    DEFF Research Database (Denmark)

    Hulot, G.; Olsen, Nils; Thebault, E.

    2009-01-01

    of internal origin happen to be detectable now in spherical harmonic degrees up to, perhaps, 16. All of these changes are usually attributed to changes in the core field itself, the secular variation, on the ground that the lithospheric magnetization cannot produce such signals. It has, however, been pointed...... out, on empirical grounds, that temporal changes in the field of internal origin produced by the induced part of the lithospheric magnetization could dominate the core field signal beyond degree 22. This short note revisits this issue by taking advantage of our improved knowledge of the small...... cause of the observed changes in the field of internal origin up to some critical degree, N-C, is indeed likely to be the secular variation of the core field, but that the signal produced by the time-varying lithospheric field is bound to dominate and conceal the time-varying core signal beyond...

  8. [Prenatal lead exposure related to cord blood brain derived neurotrophic factor (BDNF) levels and impaired neonatal neurobehavioral development].

    Science.gov (United States)

    Ren, L H; Mu, X Y; Chen, H Y; Yang, H L; Qi, W

    2016-06-01

    To explore the relationship between umbilical cord blood brain-derived neurotrophic factor (BDNF) and neonatal neurobehavioral development in lead exposure infants. All infants and their mother were randomly selected during 2011 to 2012, subjects were selected according to the umbilical cord blood lead concentrations, which contcentration of lead was higher than 0.48 μmol/L were taken into high lead exposure group, about 60 subjects included. Comparing to the high lead exposure group, according to gender, weight, pregnant week, length and head circumferenece, the level of cord blood lead concentration under 0.48 μmol/L were taken into control group, 60 cases included. Lead content was determined by graphite furnace atomic absorption spectrometry. Neonatal behavioral neurological assessment (NBNA) was used to determine the development of neonatal neuronal behavior. The content of BDNF was detected by ELISA. Comparing the BDNF and the NBNA score between two groups, and linear correlation was given on analysis the correlation between lead concentration in cord blood and BDNF, BDNF and the NBNA score. Lead content in high exposure group was (0.613±0.139) μmol/L, and higher than (0.336±0.142) μmol/L in low exposure group (t=3.21, PBDNF content in high exposure group which was (3.538±1.203) ng/ml was higher than low exposure group (2.464±0.918) ng/ml (t=7.60, PBDNF content was negatively correlated with NBNA summary score, passive muscle tension and active muscle tone score (r was -0.27, -0.29, -0.30, respectively, P values were BDNF was negatively correlated with neonatal neurodevelopment, may serve as a useful biomarker.

  9. Secularism in Nigeria: An Assessment | Ogoloma | AFRREV IJAH ...

    African Journals Online (AJOL)

    Secularism is not the absence of religions in the state. Rather, it is the absence of a state sponsored religion where everyone will be made to choose a religion of their choice. People are free to follow which religious tenets they like without any fear, intimidation, victimization or favour. The central and state administrations ...

  10. Environmental pollution of lead in traffic air and blood of traffic policemen in Khartoum State, Sudan.

    Science.gov (United States)

    Rahama, Salah M; Khider, Hiba E; Mohamed, Sitt Nour H; Abuelmaali, Sara A; Elaagip, Arwa H

    2011-06-01

    A cross sectional study was conducted in Khartoum State. A total of 45 males' traffic policemen were divided into two groups according to exposure to car exhaust; n=30 taken as exposed group, n=15 taken as controls, who were not exposed to car exhaust. The study was conducted to determine lead concentrations in traffic ambient air, to determine lead levels in blood of traffic policemen, and to evaluate the effect of exposure to car exhaust on traffic policemen during January 2009. The level of lead in ambient air was determined in 14 locations which were taken randomly at the intersections and entrances to the bridges using personal sampler "Cassella, U.K". The blood samples of all policemen were analyzed by atomic absorption Spectrophotometer to determine lead levels. A questionnaire was designed to assess the adverse health effects on the traffic policemen. The degree of environmental lead pollution in traffic ambient air was found to be 0.1937 +/- 0.1768 mg/m3 with range between 0.000-0.5166 mg/m3. In seven locations out of fourteen locations lead concentrations were 0.1940 and 0.5166 above the permissible level of 0.15 mg/m3 permitted internationally. Blood lead levels on traffic policemen (exposed and control groups) were found to be 2.4691 +/- 1.4065 microg/100 ml and 0.3944 +/- 1.2471 microg/100 ml respectively and there is no significant differences between the two groups where using SPSS program. A questionnaire findings were: average age mean of 35.9 +/- 7.7 years, 47.48% worked for periods of more than 20 years, 74.19% did not work before joining the traffic police, 51.6% of them recognized traffic air pollution as a problem of high level, 45.2% of them estimated it as medium, and 3.2% as low. As habits 38.71% were smokers, and for health complaints, 61.29% have various complaints of headache, fatigue, abdominal, hypertension and anemia. All these symptoms have a close relationship with lead poisoning. When we compared the results of age groups and work

  11. Why religion deserves a place in secular medicine.

    Science.gov (United States)

    Biggar, Nigel

    2015-03-01

    As a science and practice transcending metaphysical and ethical disagreements, 'secular' medicine should not exist. 'Secularity' should be understood in an Augustinian sense, not a secularist one: not as a space that is universally rational because it is religion-free, but as a forum for the negotiation of rival reasonings. Religion deserves a place here, because it is not simply or uniquely irrational. However, in assuming his rightful place, the religious believer commits himself to eschewing sheer appeals to religious authorities, and to adopting reasonable means of persuasion. This can come quite naturally. For example, Christianity (theo)logically obliges liberal manners in negotiating ethical controversies in medicine. It also offers reasoned views of human being and ethics that bear upon medicine and are not universally held-for example, a humanist view of human dignity, the bounding of individual autonomy by social obligation, and a special concern for the weak. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. Paracelsus, Paracelsianism, and the secularization of the worldview.

    Science.gov (United States)

    Webster, Charles

    2002-03-01

    This paper examines Paracelsus and Paracelsianism in the light of the ideas of Max Weber concerning the social consequences of the Reformation, with special reference to his theories of Entzauberung and secularization. He linked these tendencies both to the rise of capitalism and the growth of experimental science. The detailed case study of Paracelsus' account of diseases linked with saints, in common with his interpretation of many other conditions, demonstrates that he self-consciously extended the boundaries of medicine and eroded the role of magic and witchcraft associated with the church. On the other hand, Paracelsus adopted the Neoplatonic worldview, was immersed in popular magic, and evolved a system of medicine that self-consciously revolved around magic. These factors seem to place a distinct limit on his role in the demystification of knowledge. However, the magic of Paracelsus entailed a decisive break with the entrenched elitist and esoteric tradition of the occultists and hermeticists. It is argued that this reconstructed magic re-establishes the credentials of Paracelsus as a significant contributor to the disenchantment and secularization of the worldview.

  13. Blood lead, parental marital status and the risk of attention-deficit/hyperactivity disorder in elementary school children: A longitudinal study.

    Science.gov (United States)

    Choi, Won-Jun; Kwon, Ho-Jang; Lim, Myung Ho; Lim, Ji-Ae; Ha, Mina

    2016-02-28

    The aim of this study was to investigate the blood lead level and parental marital status that might influence the development of attention-deficit/hyperactivity disorder (ADHD) symptoms in school-aged children. The participants in the survey included elementary school children, and they were followed up biennially. The participants' parents or caregivers were administered a questionnaire including ADHD rating scale. Among 2967 who were not suspected to have ADHD at baseline survey, 2195 children who took follow-up test for ADHD were evaluated. The incidence rate of suspected ADHD was 5.0% (107 cases) during the two years of the follow-up period. The geometric mean blood lead level was 1.56μg/dL. Relative risk ratio for ADHD was estimated using logistic regression analysis. After adjustment for potential confounders, ADHD developed more frequently in children with blood lead levels of >2.17μg/dL (highest quartile) (RR 1.552, 95% CI 1.002-2.403) and in children with a single parent (RR 1.805, 95% CI 1.002-3.254). The RR was 3.567 (95% CI 1.595-7.980) in children with relatively high blood lead levels (>2.17μg/dL) from single-parent families, compared with those with low blood lead and a two-parent family. The ADHD risk in association with blood lead level was modified by family status. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  14. Study of secular equilibrium reinstatement on UO2 pellets manufactured by AUC route

    International Nuclear Information System (INIS)

    Carnaval, João Paulo R.; Beltran, Dalton J.M.C.; Oliveira, Carlos A.

    2017-01-01

    The fuel assemblies manufactured by INB for Angra-1 power plant has axial blanket fuel rods which must be inspected due the columns formed by different enrichment pellets. The equipment used for inspection is built with a group of BGO scintillators detectors which measurement principle is based on the absorption of gamma rays emitted from Uranium decay. The commercial grade UF 6 used by INB is stored into cylinders type 30B. The uranium inside these cylinders is in secular equilibrium before the processing. It has been found that the AUC route causes the loss of that equilibrium because the UF 6 is volatilized from the cylinder and the uranium daughters remain in the container. As AUC is converted to powder and pellets, the secular equilibrium is restored through time. The purpose of this work is to present a study of the secular equilibrium reinstatement on UO 2 pellets manufactured by AUC route before being inspected on Rod Scanner. (author)

  15. Secular trends in menarcheal age in India-evidence from the Indian human development survey.

    Directory of Open Access Journals (Sweden)

    Praveen Kumar Pathak

    Full Text Available Evidence from a number of countries in Europe and North America point towards the secular declining trend in menarcheal age with considerable spatial variations over the past two centuries. Similar trends were reported in several developing countries from Asia, Africa and Latin America. However, data corroborating any secular trend in the menarcheal age of the Indian population remained sparse and inadequately verified.We examined secular trends, regional heterogeneity and association of socioeconomic, anthropometric and contextual factors with menarcheal age among ever-married women (15-49 years in India. Using the pseudo cohort data approach, we fit multiple linear regression models to estimate secular trends in menarcheal age of 91394 ever-married women using the Indian Human Development Survey.The mean age at menarche among Indian women was 13.76 years (95 % CI: 13.75, 13.77 in 2005. It declined by three months from 13.83 years (95% CI: 13.81, 13.85 among women born prior to 1955-1964, to nearly 13.62 years (95% CI: 13.58, 13.67 among women born during late 1985-1989. However, these aggregate national figures mask extensive spatial heterogeneity as mean age at menarche varied from 15.0 years in Himachal Pradesh during 1955-1964 (95% CI: 14.89-15.11 to about 12.1 years in Assam (95% CI: 11.63-12.56 during 1985-1989.The regression analysis established a reduction of nearly one month per decade, suggesting a secular decline in age at menarche among Indian women. Notably, the menarcheal age was significantly associated with the area of residence, geographic region, linguistic groups, educational attainment, wealth status, caste and religious affiliations among Indian women.

  16. SECULAR GROWTH AND MATURATION CHANGES IN HUNGARY IN RELATION TO SOCIOECONOMIC AND DEMOGRAPHIC CHANGES.

    Science.gov (United States)

    Bodzsar, Eva B; Zsakai, Annamaria; Mascie-Taylor, Nicholas

    2016-03-01

    This paper analyses the secular changes in the body development patterns of Hungarian children between the 1910s and the beginning of the 2000s in relation to socioeconomic and demographic changes in the country. Individual growth data of children were available from two national growth studies (1983-86, 2003-06), while sample-size weighted means of children's body dimensions were collected through regional studies between the 1920s and 1970s. Gross domestic product, Gini index, life expectancy at birth and under-5 mortality rate were used to assess the changes in economic status, income inequalities of the society and the population's general health status, respectively. Secular changes in food consumption habits were also examined. The positive Hungarian secular changes in socioeconomic status were associated with a continuous increase in children's body dimensions. The negative socioeconomic changes reflected only in wartime and post-war periods of children's growth, and the considerable socioeconomic changes at the beginning of the 1990s did not appear to influence the positive trend in children's growth. The positive secular trend in stature and body mass did not level off at the beginning of the 2000s: the socioeconomic conditions that support optimal growth and maturation could improve in Hungary.

  17. Secularity and religiosity: keystones of Turkish national identity

    Directory of Open Access Journals (Sweden)

    Sergey V. Olyunin

    2011-01-01

    Full Text Available According to many experts Turkish National Federation experiences crisis of its national identity. The article concerns the problem of secular and religious balance in Turkish nationalism. Special attention is attached to Turkey as a project and Turkey as a process, war factor in a birth of the nation, national idea reproduction, Islam nationalization and nationalism Islamisation.

  18. The use of MAGSAT data to determine secular variation.

    Science.gov (United States)

    Cain, J.C.; Frayser, J.; Muth, L.; Schmitz, D.

    1983-01-01

    A combined spatial and secular variation model of the geomagnetic field, labeled M061581, is derived from a selection of MAGSAT data. Secular variation (SV) data computed from linear fits to midnight hourly values from 19 magnetic observatories were also included in the analysis but were seen to have little effect on the model. The SV patterns from this new model are compared with those from the 1980 IGRF and with those for 1970 computed by the DGRF and with the 1960 patterns computed using the GSFC(12/66) model. Most of the features of the M061581 are identical in location and level with those of the 1980 IGRF. Together they confirm that the reversals in sign of field change seen over Asia and North America between 1965 and 1975 are reverting to the pre-1965 states. The M061581 model gives -32 nT/yr for the dipole decay rate, larger than the 70% increase already reported since 1965. -Authors

  19. Secular Feminisms and Attitudes towards Religion in the Context of a West-European Society – Flanders, Belgium

    NARCIS (Netherlands)

    van den Brandt, H.P.

    2014-01-01

    Ideologies and politics of humanism and secularism in Western Europe historically have a tensioned relationship with religion as well as with feminism and the women's movement. In this article, I aim to demonstrate the multiplicity and complexity of several recent secular feminist responses to

  20. The Role of Secularism of State on the Relationship Between Catholic Identity, Political Orientation, and Gay Rights Issues.

    Science.gov (United States)

    Hichy, Zira; Gerges, Mina Halim Helmy; Platania, Silvia; Santisi, Giuseppe

    2015-01-01

    In discussions of regulations governing same-sex marriage and adoption by gays and lesbians, the issue of state secularism is often called into question. This study aims to test the mediating effects of state secularism on the relationship between Catholic identity, political orientation, and gay civil rights. Participants were Catholic Italians who completed a questionnaire measuring the constructs under investigation. Results showed that state secularism mediates the effects of Catholic identity and political orientation on attitudes toward same-sex marriage and adoption by gays and lesbians.

  1. Measurement of Secular Motion Frequency in Miniature Paul Trap to Ascertain the Stability Parameters

    International Nuclear Information System (INIS)

    Bin, Guo; Hua, Guan; Qu, Liu; Yao, Huang; Xue-Ren, Huang; Ke-Lin, Gao

    2010-01-01

    40 Ca + ions are trapped and laser cooled in a miniature Paul trap. The secular motion was observed by the radio-frequency resonance of the ion cloud and Zeeman profile sidebands of a single ion experimentally. The trap stability parameters a and q are determined with an uncertainty under 1 % by the secular motion frequency measurement. The trap efficiency is 0.75. A practicable suggestion is given for the benefits of a new trap design. (atomic and molecular physics)

  2. Predicting Precession Rates from Secular Dynamics for Extra-solar Multi-planet Systems

    Science.gov (United States)

    Van Laerhoven, Christa

    2015-12-01

    Considering the secular dynamics of multi-planet systems provides substantial insight into the interactions between planets in those systems. Secular interactions are those that don't involve knowing where a planet is along its orbit, and they dominate when planets are not involved in mean motion resonances. These interactions exchange angular momentum among the planets, evolving their eccentricities and inclinations. To second order in the planets' eccentricities and inclinations, the eccentricity and inclination perturbations are decoupled. Given the right variable choice, the relevant differential equations are linear and thus the eccentricity and inclination behaviors can be described as a sum of eigenmodes. Since the underlying structure of the secular eigenmodes can be calculated using only the planets' masses and semi-major axes, one can elucidate the eccentricity and inclination behavior of planets in exoplanet systems even without knowing the planets' current eccentricities and inclinations. I have calculated both the eccentricity and inclination secular eigenmodes for the population of known multi-planet systems whose planets have well determined masses and periods and have used this to predict what range of pericenter precession (and nodal regression) rates the planets may have. One might have assumed that in any given system the planets with shorter periods would have faster precession rates, but I show that this is not necessarily the case. Planets that are 'loners' have narrow ranges of possible precession rates, while planets that are 'groupies' can have a wider range of possible precession rates. Several planets are expected to undergo significant precession on few-year timescales and many planets (though not the majority of planets) will undergo significant precession on decade timescales.

  3. When Science Replaces Religion: Science as a Secular Authority Bolsters Moral Sensitivity.

    Directory of Open Access Journals (Sweden)

    Onurcan Yilmaz

    Full Text Available Scientific and religious thinking compete with each other on several levels. For example, activating one generally weakens the other. Since priming religion is known to increase moral behaviour and moral sensitivity, priming science might be expected to have the opposite effect. However, it was recently demonstrated that, on the contrary, science priming increases moral sensitivity as well. The present set of studies sought to replicate this effect and test two explanations for it. Study 1 used a sentence unscrambling task for implicitly priming the concept of science but failed to replicate its effect on moral sensitivity, presumably due to a ceiling effect. Study 2 replicated the effect with a new measure of moral sensitivity. Study 3 tested whether science-related words create this effect by activating the idea of secular authority or by activating analytic thinking. It was demonstrated that words related to secular authority, but not words related to analytic thinking, produced a similar increase in moral sensitivity. Religiosity level of the participants did not influence this basic finding. The results are consistent with the hypothesis that science as a secular institution has overtaken some of the functions of religion in modern societies.

  4. When Science Replaces Religion: Science as a Secular Authority Bolsters Moral Sensitivity.

    Science.gov (United States)

    Yilmaz, Onurcan; Bahçekapili, Hasan G

    2015-01-01

    Scientific and religious thinking compete with each other on several levels. For example, activating one generally weakens the other. Since priming religion is known to increase moral behaviour and moral sensitivity, priming science might be expected to have the opposite effect. However, it was recently demonstrated that, on the contrary, science priming increases moral sensitivity as well. The present set of studies sought to replicate this effect and test two explanations for it. Study 1 used a sentence unscrambling task for implicitly priming the concept of science but failed to replicate its effect on moral sensitivity, presumably due to a ceiling effect. Study 2 replicated the effect with a new measure of moral sensitivity. Study 3 tested whether science-related words create this effect by activating the idea of secular authority or by activating analytic thinking. It was demonstrated that words related to secular authority, but not words related to analytic thinking, produced a similar increase in moral sensitivity. Religiosity level of the participants did not influence this basic finding. The results are consistent with the hypothesis that science as a secular institution has overtaken some of the functions of religion in modern societies.

  5. Evaluation of the effect of divalent metal transporter 1 gene polymorphism on blood iron, lead and cadmium levels

    Energy Technology Data Exchange (ETDEWEB)

    Kayaaltı, Zeliha, E-mail: kayaalti@ankara.edu.tr; Akyüzlü, Dilek Kaya; Söylemezoğlu, Tülin

    2015-02-15

    Divalent metal transporter 1 (DMT1), a member of the proton-coupled metal ion transporter family, mediates transport of ferrous iron from the lumen of the intestine into the enterocyte and export of iron from endocytic vesicles. It has an affinity not only for iron but also for other divalent cations including manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 is encoded by the SLC11a2 gene that is located on chromosome 12q13 in humans and express four major mammalian isoforms (1A/+IRE, 1A/-IRE, 2/+IRE and 2/-IRE). Mutations or polymorphisms of DMT1 gene may have an impact on human health by disturbing metal trafficking. To study the possible association of DMT1 gene with the blood levels of some divalent cations such as iron, lead and cadmium, a single nucleotide polymorphism (SNP) (IVS4+44C/A) in DMT1 gene was investigated in 486 unrelated and healthy individuals in a Turkish population by method of polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP). The genotype frequencies were found as 49.8% homozygote typical (CC), 38.3% heterozygote (CA) and 11.9% homozygote atypical (AA). Metal levels were analyzed by dual atomic absorption spectrometer system and the average levels of iron, lead and cadmium in the blood samples were 446.01±81.87 ppm, 35.59±17.72 ppb and 1.25±0.87 ppb, respectively. Individuals with the CC genotype had higher blood iron, lead and cadmium levels than those with AA and CA genotypes. Highly statistically significant associations were detected between IVS4+44 C/A polymorphism in the DMT1 gene and iron and lead levels (p=0.001 and p=0.036, respectively), but no association was found with cadmium level (p=0.344). This study suggested that DMT1 IVS4+44 C/A polymorphism is associated with inter-individual variations in blood iron, lead and cadmium levels. - Highlights: • DMT1 IVS4+44 C/A polymorphism is associated with inter-individual variations in blood iron, cadmium and lead levels.

  6. Evaluation of the effect of divalent metal transporter 1 gene polymorphism on blood iron, lead and cadmium levels

    International Nuclear Information System (INIS)

    Kayaaltı, Zeliha; Akyüzlü, Dilek Kaya; Söylemezoğlu, Tülin

    2015-01-01

    Divalent metal transporter 1 (DMT1), a member of the proton-coupled metal ion transporter family, mediates transport of ferrous iron from the lumen of the intestine into the enterocyte and export of iron from endocytic vesicles. It has an affinity not only for iron but also for other divalent cations including manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 is encoded by the SLC11a2 gene that is located on chromosome 12q13 in humans and express four major mammalian isoforms (1A/+IRE, 1A/-IRE, 2/+IRE and 2/-IRE). Mutations or polymorphisms of DMT1 gene may have an impact on human health by disturbing metal trafficking. To study the possible association of DMT1 gene with the blood levels of some divalent cations such as iron, lead and cadmium, a single nucleotide polymorphism (SNP) (IVS4+44C/A) in DMT1 gene was investigated in 486 unrelated and healthy individuals in a Turkish population by method of polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP). The genotype frequencies were found as 49.8% homozygote typical (CC), 38.3% heterozygote (CA) and 11.9% homozygote atypical (AA). Metal levels were analyzed by dual atomic absorption spectrometer system and the average levels of iron, lead and cadmium in the blood samples were 446.01±81.87 ppm, 35.59±17.72 ppb and 1.25±0.87 ppb, respectively. Individuals with the CC genotype had higher blood iron, lead and cadmium levels than those with AA and CA genotypes. Highly statistically significant associations were detected between IVS4+44 C/A polymorphism in the DMT1 gene and iron and lead levels (p=0.001 and p=0.036, respectively), but no association was found with cadmium level (p=0.344). This study suggested that DMT1 IVS4+44 C/A polymorphism is associated with inter-individual variations in blood iron, lead and cadmium levels. - Highlights: • DMT1 IVS4+44 C/A polymorphism is associated with inter-individual variations in blood iron, cadmium and lead levels.

  7. The association between low levels of lead in blood and occupational noise-induced hearing loss in steel workers

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Yaw-Huei [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Chiang, Han-Yueh [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Yen-Jean, Mei-Chu [Division of Family Medicine, E-Da Hospital, Taiwan, ROC 1, E-Da Rd., Jiau-Shu Tsuen, Yan-Chau Shiang, Kaohsiung County, Taiwan, ROC (China); I-Shou University, Kaohsiung County, Taiwan, ROC 1, Sec. 1, Syuecheng Rd., Da-Shu Shiang, Kaohsiung County, Taiwan, ROC (China); Wang, Jung-Der, E-mail: jdwang@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC Rm. 735, 17, Xu-Zhou Rd., Taipei, Taiwan, ROC (China); Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC No. 1, Chang-Teh St., Taipei, Taiwan, ROC (China)

    2009-12-15

    As the use of leaded gasoline has ceased in the last decade, background lead exposure has generally been reduced. The aim of this study was to examine the effect of low-level lead exposure on human hearing loss. This study was conducted in a steel plant and 412 workers were recruited from all over the plant. Personal information such as demographics and work history was obtained through a questionnaire. All subjects took part in an audiometric examination of hearing thresholds, for both ears, with air-conducted pure tones at frequencies of 500, 1000, 2000, 3000, 4000, 6000 and 8000 Hz. Subjects' blood samples were collected and analyzed for levels of manganese, copper, zinc, arsenic, cadmium and lead with inductive couple plasma-mass spectrometry. Meanwhile, noise levels in different working zones were determined using a sound level meter with A-weighting network. Only subjects with hearing loss difference of no more than 15 dB between both ears and had no congenital abnormalities were included in further data analysis. Lead was the only metal in blood found significantly correlated with hearing loss for most tested sound frequencies (p < 0.05 to p < 0.0001). After adjustment for age and noise level, the logistic regression model analysis indicated that elevated blood lead over 7 {mu}g/dL was significantly associated with hearing loss at the sound frequencies of 3000 through 8000 Hz with odds ratios raging from 3.06 to 6.26 (p < 0.05 {approx} p < 0.005). We concluded that elevated blood lead at level below 10 {mu}g/dL might enhance the noise-induced hearing loss. Future research needs to further explore the detailed mechanism.

  8. The association between low levels of lead in blood and occupational noise-induced hearing loss in steel workers

    International Nuclear Information System (INIS)

    Hwang, Yaw-Huei; Chiang, Han-Yueh; Yen-Jean, Mei-Chu; Wang, Jung-Der

    2009-01-01

    As the use of leaded gasoline has ceased in the last decade, background lead exposure has generally been reduced. The aim of this study was to examine the effect of low-level lead exposure on human hearing loss. This study was conducted in a steel plant and 412 workers were recruited from all over the plant. Personal information such as demographics and work history was obtained through a questionnaire. All subjects took part in an audiometric examination of hearing thresholds, for both ears, with air-conducted pure tones at frequencies of 500, 1000, 2000, 3000, 4000, 6000 and 8000 Hz. Subjects' blood samples were collected and analyzed for levels of manganese, copper, zinc, arsenic, cadmium and lead with inductive couple plasma-mass spectrometry. Meanwhile, noise levels in different working zones were determined using a sound level meter with A-weighting network. Only subjects with hearing loss difference of no more than 15 dB between both ears and had no congenital abnormalities were included in further data analysis. Lead was the only metal in blood found significantly correlated with hearing loss for most tested sound frequencies (p < 0.05 to p < 0.0001). After adjustment for age and noise level, the logistic regression model analysis indicated that elevated blood lead over 7 μg/dL was significantly associated with hearing loss at the sound frequencies of 3000 through 8000 Hz with odds ratios raging from 3.06 to 6.26 (p < 0.05 ∼ p < 0.005). We concluded that elevated blood lead at level below 10 μg/dL might enhance the noise-induced hearing loss. Future research needs to further explore the detailed mechanism.

  9. Lead evaluation in blood of workers of batteries industries; Evaluacion de plomo en sangre de trabajadores de industrias de baterias

    Energy Technology Data Exchange (ETDEWEB)

    Valbuena P, John J; Duarte, Martha; Clara, Marciales

    2001-07-01

    In order to evaluate the occupational risk of exposure to lead of employees working in three small industries that recycle and manufacture acid lead batteries, the lead and zinc protoporphyrine (ZPP) blood content was determined. The determination was also performed on people not exposed in order to establish comparison values. Venous blood was collected in metal free heparinized glass tubes. Lead was analyzed by atomic absorption with graphite furnace and ZPP by fluorescence. According to Colombian legislation, it was found that around 31 % workers in this type of industries are in dangerous and intoxication exposure. It was also found that 91 % of workers exceed the level of 30 mg Pb/dL blood established as standard by the American Conference governmental Industrial Hygienists (ACGIH)

  10. The continuing impact of lead dust on children's blood lead: comparison of public and private properties in New Orleans.

    Science.gov (United States)

    Mielke, Howard W; Gonzales, Chris R; Mielke, Paul W

    2011-11-01

    Compared with a maximum collective lead (Pb) estimate of ∼1811 metric tons (MT) in exterior paint on 86,000 New Orleans houses, Pb additives in gasoline were estimated at ∼12,000 MT in New Orleans, yielding ∼9100 MT Pb exhausted as aerosols from vehicles; ∼4850 MT were particles>10 μm and ∼4200 MT were particles New Orleans. This study includes 224 soil samples from 10 public housing properties and 363 soil samples from residential private properties within an 800 m radius of centroids of public housing census tracts. The Louisiana Childhood Lead Poisoning Prevention Program data from 2000 to 2005 (pre-Hurricane Katrina) was the source for 9807 children's blood Pb (μg/dL) results. Soil and blood Pb data were grouped by public housing census tracts and private residential properties. This study uses Multi-Response Permutation Procedures for statistical analysis. Brick public properties in the city core had significantly more soil Pb contamination and higher prevalence of elevated children's blood Pb than same-aged brick public properties in the outer areas of the city. The pre-Hurricane Katrina New Orleans concentration of Pb dust in the inner-city soil displayed a median of 438 mg/kg or 3.7 times larger than Pb dust in outlying areas where the median soil Pb was 117 mg/kg (p-value=2.9×10(-15)). Also, the pre-Hurricane Katrina prevalence of children's blood Pb≥10 μg/dL was 22.9% within the inner-city compared with 9.1% in the outer areas of New Orleans (p-value=3.4×10(-74)). Comparing the quantities of Pb dust from paint and Pb additives to gasoline, this study supports the later source as a more plausible explanation for the differences in soil Pb and children's blood Pb within public and private housing in the higher traffic congested inner-city core compared with the lower traffic congested outer areas of New Orleans. Similar patterns of environmental Pb dust contamination and childhood Pb exposure are expected in all cities. Copyright © 2011

  11. Secular stagnation or stagnation policy? Steindl after Summers

    Directory of Open Access Journals (Sweden)

    Eckhard Hein

    2016-03-01

    Full Text Available The debate on secular stagnation suffers from vagueness and several shortcomings, which affect its economic policy implications. In this work we provide an alternative view on the advanced economies’ tendencies to stagnation, based on Josef Steindl’s contributions. Steindl’s pioneering 1952 book in particular is not prone to several problems that affect the current debate on secular stagnation. It does not rely on the dubious notion of an equilibrium real interest rate as the equilibrating force of saving and investment at full employment levels. Rather, it is based on the notion that modern capitalist economies face aggregate demand constraints, and that saving adjusts to investment through income growth and changes in capacity utilisation in the long run. Steindl’s treatment allows for potential growth to become endogenous to actual demand, and it seriously considers the role of institutions and power relationships for long-run growth. In illustrating Steindl’s contributions on this topic, the article presents an original model synthetizing the main points in particular concerning long run growth and stagnation. JEL codes: B22, E11, E12, E65, O11

  12. Study of secular equilibrium reinstatement on UO{sub 2} pellets manufactured by AUC route

    Energy Technology Data Exchange (ETDEWEB)

    Carnaval, João Paulo R.; Beltran, Dalton J.M.C.; Oliveira, Carlos A., E-mail: joaocarnaval@inb.gov.br, E-mail: daltonbeltran@inb.gov.br, E-mail: carlossilva@inb.gov.br [Indústrias Nucleares do Brasil S.A. (INB), Resende, RJ (Brazil)

    2017-07-01

    The fuel assemblies manufactured by INB for Angra-1 power plant has axial blanket fuel rods which must be inspected due the columns formed by different enrichment pellets. The equipment used for inspection is built with a group of BGO scintillators detectors which measurement principle is based on the absorption of gamma rays emitted from Uranium decay. The commercial grade UF{sub 6} used by INB is stored into cylinders type 30B. The uranium inside these cylinders is in secular equilibrium before the processing. It has been found that the AUC route causes the loss of that equilibrium because the UF{sub 6} is volatilized from the cylinder and the uranium daughters remain in the container. As AUC is converted to powder and pellets, the secular equilibrium is restored through time. The purpose of this work is to present a study of the secular equilibrium reinstatement on UO{sub 2} pellets manufactured by AUC route before being inspected on Rod Scanner. (author)

  13. The contribution of housing renovation to children’s blood lead levels: a cohort study

    Science.gov (United States)

    2013-01-01

    Background Routine renovation of older housing is a risk factor for childhood lead poisoning, but the contribution to children’s blood lead levels is poorly defined for children with lower exposure levels. Methods We examined a prospective cohort of 276 children followed from 6 to 24 months of age. We conducted surveys of renovation activities and residential lead hazards and obtained blood lead level (B-Pb) every six months. We analyzed B-Pb in a repeated measures design using a mixed effects linear model. Results Parent reported interior renovation ranged from 11 to 25% of housing units at the four, 6-month periods. In multivariable analysis, children whose housing underwent interior renovation had a 12% higher mean B-Pb by two years of age compared with children whose housing units were not renovated (p children in non-renovated housing, children whose housing units underwent renovation in the prior month had a 17% higher mean B-Pb at two years of age, whereas children whose housing renovation occurred in the prior 2–6 months had an 8% higher mean B-Pb. We also found an association between higher paint lead loading, measured using an X-ray fluorescence (XRF) based paint lead index, and child B-Pb (p = 0.02); for every 10 mg/cm2 increase in paint lead loading index there was a 7.5% higher mean childhood B-Pb. Conclusions In an analysis of data collected before the recent changes to Environmental Protection Agency’s Lead, Renovation, Repair and Painting Rule, routine interior housing renovation was associated with a modest increase in children’s B-Pb. These results are important for the provision of clinical advice, for housing and public health professionals, and for policymakers. PMID:23981571

  14. On the side of Barrabas or on the side of Christ. The harassment again the secular private schools in Spain, 1880-1910

    Directory of Open Access Journals (Sweden)

    Luis Miguel LÁZARO LORENTE

    2013-02-01

    Full Text Available The introduction of secular education in Spain from the eighties in the nineteenth century will come from the hand of associations linked to freethinking and masonry, of Republican groups, and of anarchist groups. Since its inception, its development was extremely difficult. Funding was not readily available for premises, nor was for teachers or appropriate textbooks. But, above all, proponents of the secular school will soon have to face systematic harassment by the Spanish Church, social groups and the Conservatives who, at all levels, will oppose a fierce resistance to the timid and limited attempts of secularization in the Spanish social life. In that effort, the secular school should have played an important role, which will, in fact, be severely limited by the small number of secular schools put in place in Spain.

  15. Community- and family-level factors influence care-giver choice to screen blood lead levels of children in a mining community.

    Science.gov (United States)

    Moodie, S M; Tsui, E K; Silbergeld, E K

    2010-07-01

    Bunker Hill, in Kellogg, Idaho, formerly a lead mine (1884-1981) and smelter (1917-1981), is now a Superfund site listed on the Environmental Protection Agency's (EPA) National Priorities List. Lead contamination from the site is widespread due to past smelter discharges to land, water, and air, placing children at risk for both exposure to lead and resultant health effects of lead. Since 1983, the EPA has used child blood lead levels to inform the clean-up standards for the Bunker Hill Superfund site. This study was undertaken to examine factors that have contributed to the significant fall-off in the rates and numbers of children being screened for blood lead in Kellogg (number screened decreased from 195 to 8 from 2002 to 2007). The goal of this research project was to define community- and family-level factors which influence care-giver choice to screen blood lead levels of their children in this environment. This formative research study used mixed methods and was comprised of three research components: (1) preliminary interviews using community-based participatory research methods to define key research questions of relevance to community members, government and NGOs working in relation to the Bunker Hill clean-up; (2) a quantitative analysis of a cross-sectional household survey conducted with adult care-givers about child blood lead screening in Kellogg; and (3) ethnographic community rapid assessment methods formed the in-depth interview process and qualitative analysis. The survey showed the likelihood of blood lead screening that for children under the age of 18 years increases 34% with each one-year increase in current age of the child (95% CI, 1.08-1.67, p-value=0.009), and decreases 45% with annual household income greater than $10,000 (95% CI, 0.35-0.88, p-value=0.013). Sibling birth order increased the likelihood of blood lead screening by 61% (95% CI, 1.04-2.48, p-value=0.032) for each successive child. Female children were rated by their care

  16. Exposure to PM2.5 and Blood Lead Level in Two Populations in Ulaanbaatar, Mongolia.

    Science.gov (United States)

    Enkhbat, Undarmaa; Rule, Ana M; Resnick, Carol; Ochir, Chimedsuren; Olkhanud, Purevdorj; Williams, D'Ann L

    2016-02-15

    Approximately 60% of the households in Ulaanbaatar live in gers (a traditional Mongolian dwelling) in districts outside the legal limits of the city, without access to basic infrastructure, such as water, sewage systems, central heating, and paved roads, in contrast to apartment residents. This stark difference in living conditions creates different public health challenges for Ulaanbaatar residents. Through this research study we aim to test our hypothesis that women living in gers burning coal in traditional stoves for cooking and heating during the winter are exposed to higher concentrations of airborne PM2.5 than women living in apartments in Ulaanbaatar, Mongolia, and this exposure may include exposures to lead in coal with effects on blood lead levels. This cross-sectional study recruited a total of 50 women, 40-60 years of age, from these two settings. Air sampling was carried out during peak cooking and heating times, 5:00 p.m.-11:00 p.m., using a direct-reading instrument (TSI SidePak™) and integrated polytetrafluoroethylene (PTFE) filters using the SKC Personal Environmental Monitor. Blood lead level (BLL) was measured using a LeadCare II rapid field test method. In our study population, measured PM2.5 geometric mean (GM) concentrations using the SidePak™ in the apartment group was 31.5 (95% CI:17-99) μg/m³, and 100 (95% CI: 67-187) μg/m³ in ger households (p < 0.001). The GM integrated gravimetric PM2.5 concentrations in the apartment group were 52.8 (95% CI: 39-297) μg/m³ and 127.8 (95% CI: 86-190) μg/m³ in ger households (p = 0.004). The correlation coefficient for the SidePak™ PM2.5 concentrations and filter based PM2.5 concentrations was r = 0.72 (p < 0.001). Blood Lead Levels were not statistically significant different between apartment residents and ger residents (p = 0.15). The BLL is statistically significant different (p = 0.01) when stratified by length of exposures outside of the home. This statistically significant difference

  17. Exposure to PM2.5 and Blood Lead Level in Two Populations in Ulaanbaatar, Mongolia

    Directory of Open Access Journals (Sweden)

    Undarmaa Enkhbat

    2016-02-01

    Full Text Available Approximately 60% of the households in Ulaanbaatar live in gers (a traditional Mongolian dwelling in districts outside the legal limits of the city, without access to basic infrastructure, such as water, sewage systems, central heating, and paved roads, in contrast to apartment residents. This stark difference in living conditions creates different public health challenges for Ulaanbaatar residents. Through this research study we aim to test our hypothesis that women living in gers burning coal in traditional stoves for cooking and heating during the winter are exposed to higher concentrations of airborne PM2.5 than women living in apartments in Ulaanbaatar, Mongolia, and this exposure may include exposures to lead in coal with effects on blood lead levels. This cross-sectional study recruited a total of 50 women, 40–60 years of age, from these two settings. Air sampling was carried out during peak cooking and heating times, 5:00 p.m.–11:00 p.m., using a direct-reading instrument (TSI SidePak™ and integrated polytetrafluoroethylene (PTFE filters using the SKC Personal Environmental Monitor. Blood lead level (BLL was measured using a LeadCare II rapid field test method. In our study population, measured PM2.5 geometric mean (GM concentrations using the SidePak™ in the apartment group was 31.5 (95% CI:17–99 μg/m3, and 100 (95% CI: 67–187 μg/m3 in ger households (p < 0.001. The GM integrated gravimetric PM2.5 concentrations in the apartment group were 52.8 (95% CI: 39–297 μg/m3 and 127.8 (95% CI: 86–190 μg/m3 in ger households (p = 0.004. The correlation coefficient for the SidePak™ PM2.5 concentrations and filter based PM2.5 concentrations was r = 0.72 (p < 0.001. Blood Lead Levels were not statistically significant different between apartment residents and ger residents (p = 0.15. The BLL is statistically significant different (p = 0.01 when stratified by length of exposures outside of the home. This statistically

  18. Zero Secular Torque on Asteroids from Impinging Solar Photons in the YORP Effect: A Simple Proof

    Science.gov (United States)

    Rubincam, David Perry; Paddack, Stephen J.

    2010-01-01

    YORP torques, where "YORP" stands for "Yarokovsky-O'Keefe-Radzievskii-Paddack." arise mainly from sun light reflected off a Solar System object and the infrared radiation emi tted by it. We show here, through the most elementary demonstration that we Can devise, that secular torques from impinging solar photons are generally negligible and thus cause little secular evolution of an asteroid's obliquity or spin rate.

  19. Gravitational dynamos and the low-frequency geomagnetic secular variation.

    Science.gov (United States)

    Olson, P

    2007-12-18

    Self-sustaining numerical dynamos are used to infer the sources of low-frequency secular variation of the geomagnetic field. Gravitational dynamo models powered by compositional convection in an electrically conducting, rotating fluid shell exhibit several regimes of magnetic field behavior with an increasing Rayleigh number of the convection, including nearly steady dipoles, chaotic nonreversing dipoles, and chaotic reversing dipoles. The time average dipole strength and dipolarity of the magnetic field decrease, whereas the dipole variability, average dipole tilt angle, and frequency of polarity reversals increase with Rayleigh number. Chaotic gravitational dynamos have large-amplitude dipole secular variation with maximum power at frequencies corresponding to a few cycles per million years on Earth. Their external magnetic field structure, dipole statistics, low-frequency power spectra, and polarity reversal frequency are comparable to the geomagnetic field. The magnetic variability is driven by the Lorentz force and is characterized by an inverse correlation between dynamo magnetic and kinetic energy fluctuations. A constant energy dissipation theory accounts for this inverse energy correlation, which is shown to produce conditions favorable for dipole drift, polarity reversals, and excursions.

  20. Celebrating the Secular

    Directory of Open Access Journals (Sweden)

    Amanda Lohrey

    2013-08-01

    Full Text Available On 4 November 2004 I read a report in the Sydney Morning Herald that I found genuinely shocking, a statement by Cardinal George Pell, of the Catholic diocese of Sydney, on what’s wrong with democracy. This report was of a speech given to the Acton Institute for the Study of Religion and Liberty in the United States. In it, Dr Pell told his audience that liberal democracy is a world of ‘empty secularism’ that is over-focused on ‘individual autonomy’. The problem with democracy, said the Cardinal, quoting John Paul II, is that it is not a good thing in itself; its value depends on the moral vision that it serves, and a secular democracy is lacking in moral vision. If democracy is not a good thing in and of itself, then why have we sent troops to Iraq to enable it? And what about the principle of equality before the law? Freedom of conscience? Freedom of speech and of action? Responsibility for community? Sounds like a moral vision to me.

  1. Rapid separation of pure 144Ce fraction from fuel dissolver solution for demonstration experiment on secular equilibrium

    International Nuclear Information System (INIS)

    Ashok Kumar, G.V.S.; Kumar, R.; Venkata Subramani, C.R.

    2015-01-01

    Radioactive equilibrium is a condition in which the activity ratio of parent to its daughter is maintained constant with time which occurs only when the parent half-life is greater than daughter half-life. It is transient equilibrium in the case of the ratio of their half-lives of parent to daughter being less than an order whereas it becomes secular equilibrium when it is more than an order. In the case of secular equilibrium, the ratio of the activities becomes unity whereas the same depends on the decay constants of the parent and daughter nuclide for the transient equilibrium. 144 Ce- 144 Pr pair is a good example for the demonstration of secular equilibrium

  2. PERSONAL AND ENVIRONMENTAL RISK FACTORS SIGNIFICANTLY ASSOCIATED WITH ELEVATED BLOOD LEAD LEVELS IN RURAL THAI CHILDREN.

    Science.gov (United States)

    Swaddiwudhipong, Witaya; Kavinum, Suporn; Papwijitsil, Ratchadaporn; Tontiwattanasap, Worawit; Khunyotying, Wanlee; Umpan, Jiraporn; BoonthuM, Ratchaneekorn; Kaewnate, Yingyot; Boonmee, Sasis; Thongchub, Winai; Rodsung, Thassanee

    2014-11-01

    A community-based study was conducted to determine personal risk factors and environmental sources of lead exposure for elevated blood lead levels (≥ 10 µg/dl, EBLLs) among rural children living at the Thailand-Myanmar border in Tak Province, northwestern Thailand. Six hundred ninety-five children aged 1-14 years old were screened for BLLs. Environmental specimens for lead measurements included samples of water from the streams, taps, and household containers, house floor dust, and foods. Possible lead release from the cooking ware was determined using the leaching method with acetic acid. The overall prevalence of EBLLs was 47.1% and the geometric mean level of blood lead was 9.16 µg/dl. Personal risk factors significantly associated with EBLLs included being male, younger age, anemia, and low weight-for-age. Significant environmental risk factors were exposure to a lead-acid battery of solar energy system and use of a non-certified metal cooking pot. Some families whose children had high BLLs reported production of lead bullets from the used batteries at home. About one-third of the house dust samples taken near batteries contained lead content above the recommended value, compared with none of those taken from other areas and from the houses with no batteries. The metal pots were safe for cooking rice but might be unsafe for acidic food preparation. Both nutritional intervention and lead exposure prevention programs are essential to reduce EBLLs in this population.

  3. Determination of Lung-to-Blood Absorption Rates for Lead and Bismuth which are Appropriate for Radon Progeny

    International Nuclear Information System (INIS)

    Marsh, J.W.; Birchall, A.

    1999-01-01

    The ICRP Publication 66 Human Respiratory Tract Model (HRTM) treats clearance as a competitive process between absorption into blood and particle transport to the gastrointestinal tract and lymphatics. The ICRP recommends default absorption rates for lead and bismuth in ICRP Publication 71 but states that the values are not appropriate for short-lived radon progeny. This paper describes an evaluation of published data from volunteer experiments to estimate the absorption half-times of lead and bismuth that are appropriate for short-lived radon progeny. The absorption half-time for lead was determined to be 10±2 h, based on 212 Pb lung and blood retention data from several studies. The absorption half-time for bismuth was estimated to be about 13 h, based on 212 Bi urinary excretion data from one experiment and the ICRP biokinetic model for bismuth as a decay product of lead. (author)

  4. Dietary and inhalation intake of lead and estimation of blood lead levels in adults and children in Kanpur, India.

    Science.gov (United States)

    Sharma, Mukesh; Maheshwari, Mayank; Morisawa, S

    2005-12-01

    This research was initiated to study lead levels in various food items in the city of Kanpur, India, to assess the dietary intake of lead and to estimate blood lead (PbB) levels, a biomarker of lead toxicity. For this purpose, sampling of food products, laboratory analysis, and computational exercises were undertaken. Specifically, six food groups (leafy vegetables, nonleafy vegetables, fruits, pulses, cereals, and milk), drinking water, and lead air concentration were considered for estimating lead intake. Results indicated highest lead content in leafy vegetables followed by pulses. Fruits showed low lead content and drinking water lead levels were always within tolerable limits. It was estimated that average daily lead intake through diet was about 114 microg/day for adults and 50 microg/day in children; tolerable limit is 250 microg/day for adults and 90 microg/day for children. The estimated lead intakes were translated into the resultant PbB concentrations for children and adults using a physiologically-based pharmacokinetic (PBPK) model. Monte Carlo simulation of PbB level variations for adults showed that probability of exceeding the tolerable limit of PbB (i.e.,10 microg/dL) was 0.062 for the pre-unleaded and 0.000328 for the post-unleaded gasoline period. The probability of exceeding tolerable limits in PbB level was reduced by a factor of 189 in the post-unleaded scenario. The study also suggested that in spite of the introduction of unleaded gasoline, children continue to be at a high risk (probability of exceeding 10 microg/dL = 0.39) because of a high intake of lead per unit body weight.

  5. The Possibility of Religion in a Scientific and Secular Culture ...

    African Journals Online (AJOL)

    ... anthropological arguments in the modern period, to a contemporary argument from interpersonal relationships, a deepening insight into human nature produces an evermore comprehensive conception of a god, one that is not incompatible with a scientific worldview, or the secular rejection of the supernatural in the name ...

  6. Secular Life Philosophy as a Subject in Schools in Norway.

    Science.gov (United States)

    Horn, Kristian

    1981-01-01

    In Norway changes in legislation in recent years have loosened the firm hold of Christian philosophy in the schools and given room for alternative secular philosophy. This article presents background information and an outline of the basic plan for life philosophy as a school subject. (Author/SJL)

  7. Religion and modernity in a secular city: A public theology of ...

    African Journals Online (AJOL)

    2011-07-20

    Jul 20, 2011 ... The theme of the conference,1 'Religion and Modernity in a Secular City', brings together old enemies who ...... and Habermas seek it, but a language of pure mathematics, .... 236–252, Harvard University Press, Cambridge.

  8. Do US Ambient Air Lead Levels Have a Significant Impact on Childhood Blood Lead Levels: Results of a National Study

    Directory of Open Access Journals (Sweden)

    LuAnn L. Brink

    2013-01-01

    Full Text Available Introduction. Although lead paint and leaded gasoline have not been used in the US for thirty years, thousands of US children continue to have blood lead levels (BLLs of concern. Methods. We investigated the potential association of modeled air lead levels and BLLs ≥ 10 μg/dL using a large CDC database with BLLs on children aged 0–3 years. Percent of children with BLLs ≥ 10 μg/dL (2000–2007 by county and proportion of pre-50 housing and SES variables were merged with the US EPA's National Air Toxics Assessment (NATA modeled air lead data. Results. The proportion with BLL ≥ 10 μg/dL was 1.24% in the highest air lead counties, and the proportion with BLL ≥ 10 μg/dL was 0.36% in the lowest air lead counties, resulting in a crude prevalence ratio of 3.4. Further analysis using multivariate negative binomial regression revealed that NATA lead was a significant predictor of % BLL ≥ 10 μg/dL after controlling for percent pre-l950 housing, percent rural, and percent black. A geospatial regression revealed that air lead, percent older housing, and poverty were all significant predictors of % BLL ≥ 10 μg/dL. Conclusions. More emphasis should be given to potential sources of ambient air lead near residential areas.

  9. A simple lead dust fall method predicts children's blood lead level: New evidence from Australia.

    Science.gov (United States)

    Gulson, Brian; Taylor, Alan

    2017-11-01

    We have measured dust fall accumulation in petri dishes (PDD) collected 6 monthly from inside residences in Sydney urban area, New South Wales, Australia as part of a 5-year longitudinal study to determine environmental associations, including soil. with blood lead (PbB) levels. The Pb loading in the dishes (n = 706) had geometric means (GM) of 24µg/m 2 /30d, a median value of 22µg/m 2 /30d with a range from 0.2 to 11,390µg/m 2 /30d. Observed geometric mean PbB was 2.4µg/dL at ages 2-3 years. Regression analyses showed a statistically significant relationship between predicted PbB and PDD. The predicted PbB values from dust in our study are consistent with similar analyses from the US in which floor dust was collected by wipes. Predicted PbB values from PDD indicate that an increase in PDD of about 100µg/m 2 /30d would increase PbB by about 1.5µg/dL or a doubling PbB at the low levels currently observed in many countries. Predicted PbB values from soil indicate that a change from 0 to 1000mg Pb/kg results in an increase of 1.7µg/dL in PbB, consistent with earlier investigations. Blood Pb levels can be predicted from dust fall accumulation (and soil) in cases where blood sampling is not always possible, especially in young children. Petri dish loading data could provide an alternative or complementary "action level" at about 100µg Pb/m 2 /30 days, similar to the suggested level of about 110µg Pb/m 2 for surface wipes, for use in monitoring activities such as housing rehabilitation, demolition or soil resuspension. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Blood Lead Levels and Cause-Specific Mortality of Inorganic Lead-Exposed Workers in South Korea.

    Directory of Open Access Journals (Sweden)

    Min-Gi Kim

    Full Text Available The objective of this study was to identify the association of blood lead level (BLL with mortality in inorganic lead-exposed workers of South Korea. A cohort was compiled comprising 81,067 inorganic lead exposed workers working between January 1, 2000, and December 31, 2004. This cohort was merged with the Korean National Statistical Office to follow-up for mortality between 2000 and 2008. After adjusting for age and other carcinogenic metal exposure, all-cause mortality (Relative risk [RR] 1.36, 95% confidence interval [CI] 1.03-1.79, digestive disease (RR 3.23, 95% CI 1.33-7.86, and intentional self-harm (RR 2.92, 95% CI 1.07-7.81 were statistically significantly higher in males with BLL >20 μg/dl than of those with BLL ≤10μg/dl. The RR of males with BLL of 10-20 μg/dl was statistically higher than of those with BLL ≤10μg/dl in infection (RR 3.73. 95% CI, 1.06-13.06. The RRs of females with 10-20 μg/dl BLL was statistically significantly greater than those with BLL <10μg/dl in all-cause mortality (RR 1.93, 95% CI 1.16-3.20 and colon and rectal cancer (RR 13.42, 95% CI 1.21-149.4. The RRs of females with BLL 10-20 μg/dl (RR 10.45, 95% CI 1.74-62.93 and BLL ≥20 μg/dl (RR 12.68, 95% CI 1.69-147.86 was statistically significantly increased in bronchus and lung cancer. The increased suicide of males with ≥20 μg/dl BLLs, which might be caused by major depression, might be associated with higher lead exposure. Also, increased bronchus and lung cancer mortality in female workers with higher BLL might be related to lead exposure considering low smoking rate in females. The kinds of BLL-associated mortality differed by gender.

  11. Teaching about Religion in History Classes: Sacred and Secular History.

    Science.gov (United States)

    Abrahamson, Brant; Smith, Fred

    In teaching about religion there is the fundamental distinction between secular history, which is restricted to natural cause and effect relationships, and sacred histories, which assume that a spirit world exists and that human/divine interaction has taken place. In the United States, the academically approved way of dealing with these…

  12. The sacred, the secular, and the profane

    DEFF Research Database (Denmark)

    Tsinovoi, Alexei

    2017-01-01

    types of power relations, which can provide a basis for critical re-formulation of the concepts of securitisation and desecuritisation. The article illustrates the analytical purchase of these ideal types through an analysis of the politics of Israel’s natural gas discoveries. Due to neoliberal reforms......In security studies, the dichotomy between ‘security’ and ‘regular’ politics has been effectively challenged in recent years, both theoretically and empirically. To address this challenge, the article develops Giorgio Agamben’s concepts of the sacred, the profane and the secular into three ideal...

  13. Elevated blood-lead levels among children living in the rural Philippines.

    Science.gov (United States)

    Riddell, Travis J; Solon, Orville; Quimbo, Stella A; Tan, Cheryl May C; Butrick, Elizabeth; Peabody, John W

    2007-09-01

    Generally, lead poisoning is not considered a significant environmental hazard for children in rural areas of developing countries. With a prospectively designed policy experiment, the research community and the government are conducting a broad-based investigation to introduce and evaluate the impact of health policy reforms on children in a rural area of the Philippines - the Quality Improvement Demonstration Study (QIDS). As part of this study, we researched lead exposure in children under the age of five. We sampled a population of children from the Visayas region in the central Philippines, covering approximately one third of the country's geographical area. From December 2003 to September 2004, the survey collected blood lead levels (BLL) together with demographic, socioeconomic and child health data points. Supplemental field-testing among a sub-sample of the most exposed children assessed the sources of environmental lead exposure. Among children in this study, 21% (601 of 2861 children) had BLL greater than 10 microg/dl. BLL were associated independently with age, haemoglobin concentration, water source, roofing material, expenditures and history of breastfeeding. A follow-up assessment of possible environmental exposures among the sub-sample of children with elevated BLL revealed no single or predominant exposure source. Instead, there appear to be multiple potential sources, such as fossil-fuel combustion, lead paint (in or around 38% of homes) and household items. Elevated BLL are common among children in the Visayas, and may signify an under-recognized threat to children living in rural areas of other developing nations. This setting has varied environmental sources of lead. Observed correlates of BLL may be of clinical, environmental and public health utility to identify and mitigate the consequences of lead toxicity.

  14. Association of Blood and Seminal Plasma Cadmium and Lead Levels With Semen Quality in Non-Occupationally Exposed Infertile Men in Abakaliki, South East Nigeria

    Directory of Open Access Journals (Sweden)

    Ademola C Famurewa

    2017-10-01

    Full Text Available Objective: To evaluate association of blood and seminal plasma lead and cadmium with sperm quality of non-occupationally exposed male partners of couples with infertility.Materials and methods: A cross-sectional study was conducted on 75 men aged 20-45 years (mean = 37.1 ± 7.0 yrs. with infertility recruited from the Fertility Clinic of a hospital in Abakaliki. Sperm count done in accordance with the WHO guidelines was used to classify the participants as normospamia, oligospermia and azospermia. Atomic absorption spectrophotometer was used to determine lead and cadmium levels in plasma from blood and semen.Results: There were 15 azospermics, 22 oligospermics and 36 normospermics. Seminal and blood plasma cadmium as well as blood plasma lead were significantly (p < 0.01 higher in azospermic and oligospermic men compared to normospermic men. However, while seminal plasma lead was significantly (p < 0.05 higher in oligospermic and normospernic men than in azospermic men, the seminal plasma lead was comparable between oligospermic and normospermic men. Significant inverse associations (p < 0.01 were found between blood and seminal cadmium levels and sperm count, motility and morphology; blood lead was inversely correlated with sperm count only.Conclusion: The study suggests that environmental exposure to cadmium and lead may contribute to development of poor sperm quality and infertility in men of reproductive age in Nigeria.

  15. The relationship between blood lead levels and periodontal bone loss in the United States, 1988-1994.

    OpenAIRE

    Dye, Bruce A; Hirsch, Rosemarie; Brody, Debra J

    2002-01-01

    An association between bone disease and bone lead has been reported. Studies have suggested that lead stored in bone may adversely affect bone mineral metabolism and blood lead (PbB) levels. However, the relationship between PbB levels and bone loss attributed to periodontal disease has never been reported. In this study we examined the relationship between clinical parameters that characterize bone loss due to periodontal disease and PbB levels in the U.S. population. We used data from the T...

  16. The practice of mindfulness: from Buddhism to secular mainstream in a post-secular society

    Directory of Open Access Journals (Sweden)

    Liselotte Frisk

    2014-01-01

    Full Text Available The article focuses on the practice of mindfulness, which has migrated from being part of a religion, Buddhism, to being an integral part of Western psychology. Mindfulness is especially used in cognitive behavioural therapy, but also in, e.g., dialectical behavioural therapy (DBT and acceptance and commitment therapy (ACT. In Sweden several doctors, psychologists and psychiatrists use and recommend mindfulness for therapeutic purposes. Mindfulness is used today in many segments of mainstream medical and therapeutic care. Mindfulness is also used outside the mainstream medical and therapeutic sector, in the area of personal development or spirituality, as well as in more traditional Buddhist groups and innovative Buddhist groups such as vipassana groups. This paper investigates the migration of mindfulness from a religious to a secular sphere, and discusses whether mindfulness is a religious practice or not.

  17. Risk factors associated with the blood lead levels of children in the Community of Madrid in 2010

    Directory of Open Access Journals (Sweden)

    José María Ordóñez-Iriarte

    2013-12-01

    Full Text Available Introduction: Lead is a toxic element for humans, with children being the most vulnerable population.Objective: To find out the risk factors associated to the existing blood lead levels (BLLs of children in the Community of Madrid, after 9 years of lead being banned in gasoline.Methods: A cross-sectional study was carried out in 2010 with a sample of 85 children, less than 15 years of age, recruited via the outpatients’ service of the Pediatrics Department of the Hospital Clínico San Carlos in Madrid. Routine blood tests provided the opportunity for determining other blood parameters. Lead levels were measured using electrothermal-atomization atomic absorption spectrometry with the Zeeman-effect background correction. In addition, a survey was undertaken directed to the parents for gathering information about a series of socioeconomic and environmental variables.Results: The arithmetic mean of the BLLs in the children was 1.1 μg/dL (SD=0.7 μg/dL with a range from 0.1 μg/dL to 3.4 μg/dL. The geometric mean was 0.9 μg/dL (SD= 1.1 μg/dL. The risk factors associated to these BLLs are the following: playing in the street; low educational level of the parents; leisure activities of one of the parents linked to lead; tobacco smoking of the father; and drinking tap water.Conclusions: The BLLs of the children in the Community of Madrid have decreased, but there are still sociodemographic and environmental risk factors associated to the present levels.

  18. Associated factors for higher lead and cadmium blood levels, and reference values derived from general population of São Paulo, Brazil

    International Nuclear Information System (INIS)

    Kira, Carmen Silvia; Sakuma, Alice Momoyo; De Capitani, Eduardo Mello; Umbelino de Freitas, Clarice; Cardoso, Maria Regina Alves; Gouveia, Nelson

    2016-01-01

    Human activities are associated with emissions of various metals into the environment, among which the heavy metals lead and cadmium stand out, as they pose a risk to human life even at low concentrations. Thus, accurate knowledge of the levels of these metals exhibited by the overall population, including children, is important. The aim of this study was to estimate the concentrations of lead and cadmium in the blood of adults, adolescents and children residing in the city of São Paulo, assess factors associated with higher lead and cadmium blood levels, and to establish reference values for this population. The study sample consisted of 669 adults over 20 years old, 264 adolescents aged 12 to 19 years old and 391 children under 11 years old from both genders. The samples were collected at the end of 2007 and during 2008 in different city zones. Higher blood lead concentration was significantly associated with gender, smoking, offal intake, area of residence and age. The blood cadmium concentration was significantly associated with gender, smoking, consumption of distilled beverages and age. The reference values of lead and cadmium established for adults above 20 years old were 33 μg/L and 0.6 μg/L, respectively, for adolescents (12 to 19 years old) were 31 μg/L and 0.6 μg/L, respectively and for children under 11 years old were 29 μg/L and 0.2 μg/L, respectively. The results of this study indicate that the exposure levels of the investigated population to lead and cadmium are low. - Highlights: • The exposure of population of São Paulo city to lead and cadmium is low. • Pb level was associated with gender, smoking, offal intake, area of residence, age. • Cd level was associated with gender, smoking, distilled beverages, age. • RV for Pb in blood for children and adolescents were 29 and 31 μg/L, respectively. • RV for Cd in blood for children and adolescents were 0.2 and 0.6 μg/L, respectively.

  19. Associated factors for higher lead and cadmium blood levels, and reference values derived from general population of São Paulo, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Kira, Carmen Silvia, E-mail: carmkira@ial.sp.gov.br [Instituto Adolfo Lutz, Centro de Materiais de Referência, Av. Dr. Arnaldo, 355, São Paulo, SP CEP 01246-000 (Brazil); Sakuma, Alice Momoyo [Instituto Adolfo Lutz, Centro de Materiais de Referência, Av. Dr. Arnaldo, 355, São Paulo, SP CEP 01246-000 (Brazil); De Capitani, Eduardo Mello [Universidade Estadual de Campinas — UNICAMP, Faculdade de Ciências Médicas, Departamento de Clínica Médica, Centro de Controle de Intoxicações (Brazil); Umbelino de Freitas, Clarice [Secretaria de Estado da Saúde/SP, Coordenadoria de Controle de Doenças (Brazil); Cardoso, Maria Regina Alves [Universidade de São Paulo, Faculdade de Saúde Pública, Departamento de Epidemiologia (Brazil); Gouveia, Nelson [Universidade de São Paulo — USP, Faculdade de Medicina, Departamento de Medicina Preventiva (Brazil)

    2016-02-01

    Human activities are associated with emissions of various metals into the environment, among which the heavy metals lead and cadmium stand out, as they pose a risk to human life even at low concentrations. Thus, accurate knowledge of the levels of these metals exhibited by the overall population, including children, is important. The aim of this study was to estimate the concentrations of lead and cadmium in the blood of adults, adolescents and children residing in the city of São Paulo, assess factors associated with higher lead and cadmium blood levels, and to establish reference values for this population. The study sample consisted of 669 adults over 20 years old, 264 adolescents aged 12 to 19 years old and 391 children under 11 years old from both genders. The samples were collected at the end of 2007 and during 2008 in different city zones. Higher blood lead concentration was significantly associated with gender, smoking, offal intake, area of residence and age. The blood cadmium concentration was significantly associated with gender, smoking, consumption of distilled beverages and age. The reference values of lead and cadmium established for adults above 20 years old were 33 μg/L and 0.6 μg/L, respectively, for adolescents (12 to 19 years old) were 31 μg/L and 0.6 μg/L, respectively and for children under 11 years old were 29 μg/L and 0.2 μg/L, respectively. The results of this study indicate that the exposure levels of the investigated population to lead and cadmium are low. - Highlights: • The exposure of population of São Paulo city to lead and cadmium is low. • Pb level was associated with gender, smoking, offal intake, area of residence, age. • Cd level was associated with gender, smoking, distilled beverages, age. • RV for Pb in blood for children and adolescents were 29 and 31 μg/L, respectively. • RV for Cd in blood for children and adolescents were 0.2 and 0.6 μg/L, respectively.

  20. Secular trends of growth and pubertal maturation of school children in Southern Thailand.

    Science.gov (United States)

    Jaruratanasirikul, Somchit; Sriplung, Hutcha

    2015-01-01

    In Thailand, studies of growth date back to 1975, but there have been no studies examining any trends in increasing/decreasing growth. To determine if there have been any secular trends of increasing/decreasing growth and/or ages at puberty in Thai children. In 2012, a cross-sectional study of growth was conducted in 3460 children. The median heights and weights and the ages of pubertal maturation were compared with previous studies. Correlations between the secular trends and the health statistics indicators were calculated. From 1975-2012, the median final height of boys and girls had increased by 1.32 and 0.86 cm/decade and weight by 2.49 and 1.76 kg/decade, respectively. In girls, the age at thelarche and menarche had declined by 0.39 and 0.12 years/decade, respectively. In boys, the age at testicular enlargement Tanner II had declined by 0.15 years/decade. Increased physical growth was positively correlated to life expectancy, per capita income and prevalence of overweight/obesity was negatively correlated to prevalence of malnutrition and under-five mortality rate. The positive secular trend towards an increase in growth and a decline in the age at onset of puberty of Thai children is correlated with improvements in overall living conditions in Thailand.

  1. Formation of the Russian Federation as a secular state (XVII century - beginning of the XXI century: historical and theoretical aspects

    Directory of Open Access Journals (Sweden)

    Igor Pibaev

    2015-10-01

     Abstract: The article examines main stages of formation of the secular state in the Russian Federation. The author provides historical and legal overview of the development of secularism in Russia in the period starting from 1701 to the present days.

  2. Association of blood lead levels in children 0-72 months with living in Mid-Appalachia: a semi-ecologic study.

    Science.gov (United States)

    Wiener, R Constance; Jurevic, Richard J

    2016-01-01

    Lead exposure in children remains a significant public health issue, although many advances have been made. The Mid-Appalachia area (Kentucky, New York, Ohio, Pennsylvania, and West Virginia) is 89-91% rural with a population density of 16-21 people/km2 (41-54 people/mi2). Mid-Appalachia has significant health disparities including concerns for the consequences of greater lead exposure to children due to mining and industrial footprints, and existing older housing. The purpose of this study is to compare the reported blood lead levels of screened children, aged 0-72 months in Mid-Appalachia, to the children in the USA in general. Data from the Centers for Disease Control and Prevention and from the US Census Bureau were analyzed in a semi-ecological study. The blood lead level of 5 μg/dL was compared between children in Mid-Appalachia and the US housing units built before 1950; US housing units built before 1940 were also compared. The number of children with blood lead levels of 5 μg/dL was significantly greater in Mid-Appalachia than nationally (7.75% vs 5.79%, respectively; pecological relationship with the number of homes built before 1950 and before 1940.

  3. Assessment of lead in blood samples of children residing in the vicinity of industries

    International Nuclear Information System (INIS)

    Shah, F.; Kazi, T.G.; Afridi, H.I.; Brahaman, K.D.; Arain, S.S.; Panhwar, A.H.

    2013-01-01

    The aim of present study was to determine the lead (Pb) distributions in blood and prevalence of elevated Pb exposure among children, age ranged (5-10 years), residing near industrialized region of Hyderabad city, Pakistan. For comparison, biological samples of children of same age group from non-industrial area were also analyzed. The Pb concentration in blood samples was determined by electrothermal atomic absorption spectrometry, prior to microwave assisted acid digestion. The results showed that significantly higher proportion of children living in the vicinity of industrial area, had blood Pb levels (BLL) in the range of 15.4-35.6 micro g/dL, and 8.51-16.7 micro g/dL for those of non-industrial area. The blood Pb level was higher in boys of both groups as compared to girls of same age group, but the difference was not significant (p=0.178). Negative correlation was observed between BLL and hemoglobin levels (p<0.001), while positive correlation was observed between BLL and age. (author)

  4. Secular trends in the geologic record and the supercontinent cycle

    Science.gov (United States)

    Bradley, Dwight C.

    2011-01-01

    Geologic secular trends are used to refine the timetable of supercontinent assembly, tenure, and breakup. The analysis rests on what is meant by the term supercontinent, which here is defined broadly as a grouping of formerly dispersed continents. To avoid the artificial pitfall of an all-or-nothing definition, quantitative measures of “supercontinentality” are presented: the number of continents, and the area of the largest continent, which both can be gleaned from global paleogeographic maps for the Phanerozoic. For the secular trends approach to be viable in the deep past when the very existence of supercontinents is debatable and reconstructions are fraught with problems, it must first be calibrated in the Phanerozoic against the well-constrained Pangea supercontinent cycle. The most informative geologic variables covering both the Phanerozoic and Precambrian are the abundances of passive margins and of detrital zircons. Both fluctuated with size of the largest continent during the Pangea supercontinent cycle and can be quantified back to the Neoarchean. The tenure of Pangea was a time represented in the rock record by few zircons and few passive margins. Thus, previously documented minima in the abundance of detrital zircons (and orogenic granites) during the Precambrian (Condie et al., 2009a, Gondwana Research 15, 228–242) now can be more confidently interpreted as marking the tenures of supercontinents. The occurrences of carbonatites, granulites, eclogites, and greenstone-belt deformation events also appear to bear the imprint of Precambrian supercontinent cyclicity. Together, these secular records are consistent with the following scenario. The Neoarchean continental assemblies of Superia and Sclavia broke up at ca. 2300 and ca. 2090 Ma, respectively. Some of their fragments collided to form Nuna by about 1750 Ma; Nuna then grew by lateral accretion of juvenile arcs during the Mesoproterozoic, and was involved in a series of collisions at ca. 1000 Ma

  5. Secular variations of radon in metropolitan Vancouver, British Columbia, Canada

    International Nuclear Information System (INIS)

    Ghomshei, M.M.; Slawson, W.F.

    1990-01-01

    In this paper sampling of radon within the soil from three sites in metropolitan Vancouver is reported. Alpha trace bi-weekly measurements during a period of 4 years show secular variations with a period of 8-15 months. There are low-radon and high-radon episodes enduring several months to a year. Average radon level during the high-radon episodes reaches 5-10 times that of the low-radon periods. During high-radon episodes the high-frequency variations show very high amplitudes. After filtering of the high-frequency fluctuations, the data from different sites demonstrate remarkably similar trends. It is suggested that along with hydrogeological events, stress relaxation in rocks, earthquake, and magma emplacement may contribute to the sources of secular variations of radon. Because of long-term variations, radon level in urban areas should be monitored on a continuous basis. Single measurements, even those integrating radiation over a period of few months, may sample a low-radon episode, and provide a false assurance, or occur during a high-radon episode and give a false alarm

  6. Secular trends in Cherokee cranial morphology: Eastern vs Western bands.

    Science.gov (United States)

    Sutphin, Rebecca; Ross, Ann H; Jantz, Richard L

    2014-01-01

    The research objective was to examine if secular trends can be identified for cranial data commissioned by Boas in 1892, specifically for cranial breadth and cranial length of the Eastern and Western band Cherokee who experienced environmental hardships. Multiple regression analysis was used to test the degree of relationship between each of the cranial measures: cranial length, cranial breadth and cephalic index, along with predictor variables (year-of-birth, location, sex, admixture); the model revealed a significant difference for all craniometric variables. Additional regression analysis was performed with smoothing Loess plots to observe cranial length and cranial breadth change over time (year-of-birth) separately for Eastern and Western Cherokee band females and males born between 1783-1874. This revealed the Western and Eastern bands show a decrease in cranial length over time. Eastern band individuals maintain a relatively constant head breadth, while Western Band individuals show a sharp decline beginning around 1860. These findings support negative secular trend occurring for both Cherokee bands where the environment made a detrimental impact; this is especially marked with the Western Cherokee band.

  7. A Western Diet Pattern Is Associated with Higher Concentrations of Blood and Bone Lead among Middle-Aged and Elderly Men.

    Science.gov (United States)

    Wang, Xin; Ding, Ning; Tucker, Katherine L; Weisskopf, Marc G; Sparrow, David; Hu, Howard; Park, Sung Kyun

    2017-07-01

    Background: Little is known about the effects of overall dietary pattern on lead concentration. Objective: We examined the association of overall dietary patterns, derived from a semiquantitative food frequency questionnaire, with bone and blood lead concentrations. Methods: These longitudinal analyses included mostly non-Hispanic white, middle-aged-to-elderly men from the Veterans Affairs Normative Aging Study. Long-term lead exposures were measured as tibia and patella lead concentrations by using K-shell-X-ray fluorescence. Short-term lead exposures were measured as blood lead concentrations by using graphite furnace atomic absorption spectroscopy. Dietary pattern scores were derived by using factor analysis. Linear mixed-effects models were utilized to predict blood lead concentrations among 983 men, aged 44-92 y at baseline, with a total of 3273 observations (during 1987-2008). We constructed linear regression models to determine the relations between dietary patterns and bone lead concentrations among 649 participants with an age range of 49-93 y. Results: Two major dietary patterns were identified: a prudent dietary pattern, characterized by high intakes of fruit, legumes, vegetables, whole grains, poultry, and seafood; and a Western dietary pattern, characterized by high intakes of processed meat, red meat, refined grains, high-fat dairy products, French fries, butter, and eggs. After adjusting for age, smoking status, body mass index, total energy intake, education, occupation, neighborhood-based education and income level, men in the highest tertile of the Western pattern score (compared with the lowest) had 0.91 μg/dL (95% CI: 0.41, 1.42 μg/dL) higher blood lead, 5.96 μg/g (95% CI: 1.76, 10.16 μg/g) higher patella lead, and 3.83 μg/g (95% CI: 0.97, 6.70 μg/g) higher tibia lead. No significant association was detected with the prudent dietary pattern in the adjusted model. Conclusions: These findings suggest that the Western diet is associated with

  8. Geomagnetic secular variation at the African observatories

    International Nuclear Information System (INIS)

    Haile, T.

    2002-10-01

    Geomagnetic data from ten observatories in the African continent with time series data length of more than three decades have been analysed. All-day annual mean values of the D, H and Z components were used to study secular variations in the African region. The residuals in D, H and Z components obtained after removing polynomial fits have been examined in relation to the sunspot cycle. The occurrence of the 1969-1970 worldwide geomagnetic impulse in each observatory is studied. It is found that the secular variation in the field can be represented for most of the observatories with polynomials of second or third degree. Departures from these trends are observed over the Southern African region where strong local magnetic anomalies have been observed. The residuals in the geomagnetic field components have been shown to exhibit parallelism with the periods corresponding to double solar cycle for some of the stations. A clear latitudinal distribution in the geomagnetic component that exhibits the 1969-70 jerk is shown. The jerk appears in the plots of the first differences in H for the southern most observatories of Hermanus, Hartebeesthoek, and Tsuemb, while the Z plots show the jerk for near equatorial and equatorial stations of Antananarivo, Luanda Belas, Bangui and Addis Ababa. There is some indication for this jerk in the first difference plots of D for the northern stations of M'Bour and Tamanrasset. The plots of D rather strongly suggest the presence of a jerk around 1980 at most of the stations. (author)

  9. Access to abortion and secular liberties

    Directory of Open Access Journals (Sweden)

    Roberto Arriada Lorea

    2007-01-01

    Full Text Available In Brazil, facing an issue like abortion requires a secular perspective since the freedom of conscience assured by the Federal Constitution places upon the State the need to regard not only different viewpoints of different religions, but more specifically assure the right to diversity existing within a same religion, as well as the right to exercise different views from those of the hierarchy of his/her own religion. As such, there is no legal barrier for the decriminalization of abortion in the country. It is up to legislators to reform the present law and decriminalize abortion, assuming the commitments Brazil has assumed with international human-rights organizations, thus assuring the efficacy of civil liberties.

  10. Secular trends on traditional ecological knowledge: An analysis of different domains of knowledge among Tsimane' men.

    Science.gov (United States)

    Reyes-García, Victoria; Luz, Ana C; Gueze, Maximilien; Paneque-Gálvez, Jaime; Macía, Manuel J; Orta-Martínez, Martí; Pino, Joan

    2013-10-01

    Empirical research provides contradictory evidence of the loss of traditional ecological knowledge across societies. Researchers have argued that culture, methodological differences, and site-specific conditions are responsible for such contradictory evidences. We advance and test a third explanation: the adaptive nature of traditional ecological knowledge systems. Specifically, we test whether different domains of traditional ecological knowledge experience different secular changes and analyze trends in the context of other changes in livelihoods. We use data collected among 651 Tsimane' men (Bolivian Amazon). Our findings indicate that different domains of knowledge follow different secular trends. Among the domains of knowledge analyzed, medicinal and wild edible knowledge appear as the most vulnerable; canoe building and firewood knowledge seem to remain constant across generations; whereas house building knowledge seems to experience a slight secular increase. Our analysis reflects on the adaptive nature of traditional ecological knowledge, highlighting how changes in this knowledge system respond to the particular needs of a society in a given point of time.

  11. Lead exposure from lead pellets: age-related accumulation in mute swans

    Energy Technology Data Exchange (ETDEWEB)

    Eskildsen, J.; Grandjean, P.

    1984-05-01

    In a cross-sectional study of adult swans and their successfully fledged young in Ringkobing Fjord, West Jutland, Denmark, 128 venous blood samples were taken during the moulting period and analyzed for lead. While the juveniles generally showed blood lead levels below 15 micrograms/100 ml (median, 11 micrograms/100 ml), the values were significantly higher in adults (median, 25 micrograms/100 ml). Adult females showed slightly higher levels than did adult males. None of the birds examined showed signs of acute lead toxicity, and increased blood levels in adults may reflect increased lead body burdens from previous ingestion of lead shot as gizzard stones.

  12. A multi-level model of blood lead as a function of air lead.

    Science.gov (United States)

    Richmond-Bryant, Jennifer; Meng, Qingyu; Davis, J Allen; Cohen, Jonathan; Svendsgaard, David; Brown, James S; Tuttle, Lauren; Hubbard, Heidi; Rice, Joann; Kirrane, Ellen; Vinikoor-Imler, Lisa; Kotchmar, Dennis; Hines, Erin; Ross, Mary

    2013-09-01

    National and local declines in lead (Pb) in blood (PbB) over the past several years coincide with the decline in ambient air Pb (PbA) concentrations. The objective of this work is to evaluate how the relationship between PbB levels and PbA levels has changed following the phase out of leaded gasoline and tightened controls on industrial Pb emissions over the past 30 years among a national population sample. Participant-level data from the National Health and Nutrition Examination Survey (NHANES) were employed for two time periods (1988-1994 and 1999-2008), and the model was corrected for housing, demographic, socioeconomic, and other covariates present in NHANES. NHANES data for PbB and covariates were merged with PbA data from the U.S. Environmental Protection Agency. Linear mixed effects models (LMEs) were run to assess the relationship of PbB with PbA; sample weights were omitted, given biases encountered with the use of sample weights in LMEs. The 1988-1994 age-stratified results found that ln(PbB) was statistically significantly associated with ln(PbA) for all age groups. The consistent influence of PbA on PbB across age groups for the years 1988-1994 suggests a ubiquitous exposure unrelated to age of the sample population. The comparison of effect estimates for ln(PbA) shows a statistically significant effect estimate and ANOVA results for ln(PbB) for the 6- to 11-year and 12- to 19-year age groups during 1999-2008. The more recent finding suggests that PbA has less consistent influence on PbB compared with other factors. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. [Civic religion, civil religion, secular religion. a historiographical investigation].

    Science.gov (United States)

    Boucheron, Patrick

    2013-01-01

    Because of its conceptual plasiticity, the term civic religion is now widely used by historians, particularly historians of the Middle Ages. Yet, as this article suggests, historians would do well to interrogate the relationships (which can be hidden) that this term bears to similar concepts such as Greek Roman civic religion, Enlightenment civil religion or even the secular religion that emerged in the work of 20(th) century thinkers.

  14. Bottom-up control of geomagnetic secular variation by the Earth's inner core

    DEFF Research Database (Denmark)

    Aubert, Julien; Finlay, Chris; Fournier, Alexandre

    2013-01-01

    of geomagnetic secular variation. Here we show that it can be reproduced provided that two mechanisms relying on the inner core are jointly considered. First, gravitational coupling5 aligns the inner core with the mantle, forcing the flow of liquid metal in the outer core into a giant, westward drifting, sheet...... release in the outer core which in turn distorts the gyre, forcing it to become eccentric, in agreement with recent core flow inversions6, 10, 11. This bottom-up heterogeneous driving of core convection dominates top-down driving from mantle thermal heterogeneities, and localizes magnetic variations......Temporal changes in the Earth’s magnetic field, known as geomagnetic secular variation, occur most prominently at low latitudes in the Atlantic hemisphere1, 2 (that is, from −90 degrees east to 90 degrees east), whereas in the Pacific hemisphere there is comparatively little activity...

  15. Baseline blood levels of manganese, lead, cadmium, copper, and zinc in residents of Beijing suburb

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Long-Lian, E-mail: Longlian57@163.com [Department of Occupational Diseases Control and Prevention, Fengtai Center for Disease Control and Prevention, Beijing 100071 (China); Lu, Ling [Department of Occupational Diseases Control and Prevention, Fengtai Center for Disease Control and Prevention, Beijing 100071 (China); Pan, Ya-Juan; Ding, Chun-Guang [Institute for Occupational Health and Poison Control in China Center for Disease Prevention and Control, Beijing 100050 (China); Xu, Da-Yong [Department of Occupational Diseases Control and Prevention, Fengtai Center for Disease Control and Prevention, Beijing 100071 (China); Huang, Chuan-Feng; Pan, Xing-Fu [Institute for Occupational Health and Poison Control in China Center for Disease Prevention and Control, Beijing 100050 (China); Zheng, Wei, E-mail: wzheng@purdue.edu [School of Health Sciences, Purdue University, West Lafayette, IN 47907 (United States)

    2015-07-15

    Baseline blood concentrations of metals are important references for monitoring metal exposure in environmental and occupational settings. The purpose of this study was to determine the blood levels of manganese (Mn), copper (Cu), zinc (Zn), lead (Pb), and cadmium (Cd) among the residents (aged 12–60 years old) living in the suburb southwest of Beijing in China and to compare the outcomes with reported values in various developed countries. Blood samples were collected from 648 subjects from March 2009 to February 2010. Metal concentrations in the whole blood were determined by ICP-MS. The geometric means of blood levels of Mn, Cu, Zn, Pb and Cd were 11.4, 802.4, 4665, 42.6, and 0.68 µg/L, respectively. Male subjects had higher blood Pb than the females, while the females had higher blood Mn and Cu than the males. There was no gender difference for blood Cd and Zn. Smokers had higher blood Cu, Zn, and Cd than nonsmokers. There were significant age-related differences in blood levels of all metals studied; subjects in the 17–30 age group had higher blood levels of Mn, Pb, Cu, and Zn, while those in the 46–60 age group had higher Cd than the other age groups. A remarkably lower blood level of Cu and Zn in this population as compared with residents of other developed countries was noticed. Based on the current study, the normal reference ranges for the blood Mn were estimated to be 5.80–25.2 μg/L; for blood Cu, 541–1475 μg/L; for blood Zn, 2349–9492 μg/L; for blood Pb, <100 μg/L; and for blood Cd, <5.30 μg/L in the general population living in Beijing suburbs. - Highlights: • Baseline blood levels of metals in residents of Beijing suburb are investigated. • BMn and BPb in this cohort are higher than those in other developed countries. • Remarkably lower blood levels of Cu and Zn in this Chinese cohort are noticed. • The reference values for blood levels of Mn, Cu, Zn, Pb, and Cd are established.

  16. Baseline blood levels of manganese, lead, cadmium, copper, and zinc in residents of Beijing suburb

    International Nuclear Information System (INIS)

    Zhang, Long-Lian; Lu, Ling; Pan, Ya-Juan; Ding, Chun-Guang; Xu, Da-Yong; Huang, Chuan-Feng; Pan, Xing-Fu; Zheng, Wei

    2015-01-01

    Baseline blood concentrations of metals are important references for monitoring metal exposure in environmental and occupational settings. The purpose of this study was to determine the blood levels of manganese (Mn), copper (Cu), zinc (Zn), lead (Pb), and cadmium (Cd) among the residents (aged 12–60 years old) living in the suburb southwest of Beijing in China and to compare the outcomes with reported values in various developed countries. Blood samples were collected from 648 subjects from March 2009 to February 2010. Metal concentrations in the whole blood were determined by ICP-MS. The geometric means of blood levels of Mn, Cu, Zn, Pb and Cd were 11.4, 802.4, 4665, 42.6, and 0.68 µg/L, respectively. Male subjects had higher blood Pb than the females, while the females had higher blood Mn and Cu than the males. There was no gender difference for blood Cd and Zn. Smokers had higher blood Cu, Zn, and Cd than nonsmokers. There were significant age-related differences in blood levels of all metals studied; subjects in the 17–30 age group had higher blood levels of Mn, Pb, Cu, and Zn, while those in the 46–60 age group had higher Cd than the other age groups. A remarkably lower blood level of Cu and Zn in this population as compared with residents of other developed countries was noticed. Based on the current study, the normal reference ranges for the blood Mn were estimated to be 5.80–25.2 μg/L; for blood Cu, 541–1475 μg/L; for blood Zn, 2349–9492 μg/L; for blood Pb, <100 μg/L; and for blood Cd, <5.30 μg/L in the general population living in Beijing suburbs. - Highlights: • Baseline blood levels of metals in residents of Beijing suburb are investigated. • BMn and BPb in this cohort are higher than those in other developed countries. • Remarkably lower blood levels of Cu and Zn in this Chinese cohort are noticed. • The reference values for blood levels of Mn, Cu, Zn, Pb, and Cd are established

  17. Lead Intoxication in Children in Birmingham

    Science.gov (United States)

    Betts, P. R.; Astley, R.; Raine, D. N.

    1973-01-01

    Of 38 children investigated between 1966 and 1971 who had a blood lead concentration greater than 37 μg/100 ml eight had encephalopathy and one died; all these eight had a blood lead concentration of 99 μg/100 ml or above. Blood lead levels are related to haemoglobin concentrations and anaemia is common in children with blood lead concentrations of 37-60 μg/100 ml, levels previously accepted as harmless. Children with blood lead concentrations greater than 60 μg/100 ml show radiological evidence of lead intoxication, and treatment for this should be considered when blood lead concentration exceeds 37 μg/100 ml. Children presenting with unexplained encephalopathy should be radiographed for evidence of lead intoxication. ImagesFIG. 2FIG. 1 PMID:4691065

  18. The Universal Constitutionalism in an Age of Religious Diversity. Western Secularism Tested by “New” Cultural Conflicts

    Directory of Open Access Journals (Sweden)

    Francesco Alicino

    2011-03-01

    Full Text Available An abridged version of this article (reported by Prof. Nicola Colaianni, University of Bari “Aldo Moro” was presented at the Seminar on “Secularism and Liberal Constitutionalism”, held at the University of LUISS “Guido Carli” (Rome on 6th July 2010.This article is due to be published in the International Review of Sociology, in 2011. SUMMARY: 1. Introduction – 2. Relation-Collaboration between the State and Churches in Constitutional Democracies – 3. The laicité à la française Tested by a Deprivatised Religious Process – 3.1. The French Rigid Secularism. Freedom (of Religion through the State – 4. Canada’s Open Secularism. The  question of Religious-Based Family Law Disputes – 4.1 Reasonable Accommodation and “New” Religious Nomoi Groups – 5. Collaboration-Relation between the State and Churches in Italy – 5.1. The Italian Secularism Tested by the New “Religious Geography” – 6. Conclusion. Abstract Under the pressing process of immigration and globalisation many Western constitutional democracies have moved from a number of religions, sharing a common culture, to today's age of diversity. As opposed to the past, the current democracies are facing the lack of overlapping consensus over the basic constitutional laws: namely, the meaning and the scope of freedom of religion, secularism, the separation Church-State, equal treatment and the rule of law. This is because individuals often come to adopt their basic values by very different ways. The nature, scope and force of such values are likely to be affected by competing and, sometimes, contested fundamental values and worldviews. From here stems the pressing tension – or dilemma – between “unity” and “diversity”. This essay starts with general considerations about the freedom of religion principle, strictly related with the “separation” as well as “collaboration” between secular States and Churches; then the author analyses three case

  19. Zeno dynamics and high-temperature master equations beyond secular approximation

    International Nuclear Information System (INIS)

    Militello, B; Messina, A; Scala, M

    2013-01-01

    Complete positivity of a class of maps generated by master equations derived beyond the secular approximation is discussed. The connection between such a class of evolutions and the physical properties of the system is analyzed in depth. It is also shown that under suitable hypotheses a Zeno dynamics can be induced because of the high temperature of the bath. (paper)

  20. Erythrocyte fluorescence and lead intoxication.

    Science.gov (United States)

    Clark, K G

    1976-01-01

    Blood samples from people exposed to inorganic lead were examined by fluorescence microscopy for excess erythrocyte porphyrin. With continued lead absorption, fluorescent erythrocytes appeared in the circulation of workers handling this metal or its compounds, and they progressively increased in number and brilliance. These changes ensued if the blood lead concentration was maintained above 2-42 mumol/l (50 mug/100 ml), and preceded any material fall in the haemoglobin value. At one factory, 62-5% of 81 symptomless workers showed erythrocyte fluorescence attributable to the toxic effects of lead. Excess fluorocytes were found in blood samples from a child with pica and three of her eight siblings. These four were subsequently shown to have slightly increased blood lead concentrations (2-03 to 2-32 mumol/l). Fluorescence microscopy for excess erythrocyte porphyrin is a sensitive method for the detection of chronic lead intoxication. A relatively slight increase in the blood lead is associated with demonstrabel changes in erythrocyte porphyrin content. The procedure requires little blood, and may be performed upon stored samples collected for lead estimation. The results are not readily influenced by contamination, and provide good confirmatory evidence for the absorption of biochemically active lead. PMID:963005

  1. Biological fractionation of lead isotopes in Sprague-Dawley rats lead poisoned via the respiratory tract.

    Directory of Open Access Journals (Sweden)

    Jing Wu

    Full Text Available It was considered that lead isotope ratios did not change during physical, chemical, or biological processes. Thus, lead isotope ratios have been used as fingerprints to identify possible lead sources. However, recent evidence has shown that the lead isotope ratios among different biological samples in human are not always identical from its lead origins in vitro. An animal experiment was conducted to explore the biological fractionation of lead isotopes in biological systems.24 male Sprague-Dawley (SD rats were divided into groups that received acute lead exposure (0, 0.02, 0.2, or 2 mg/kg body weight of lead acetate via the respiratory route every day for 5 days. Biological samples (i.e., blood, urine, and feces were collected for comparison with the lead acetate (test substance and the low-lead animal feed (diet administered to the rats. The lead isotope ratios were determined by inductively coupled plasma mass spectrometry (ICP-MS.There are significant differences (p<0.05 in lead isotope ratios between blood, urine, and feces. Moreover, a nonlinear relationship between the blood lead concentration and the blood lead isotope ratios was observed. There is also a threshold effect to the fractionation function. Only the blood isotope ratio of (204Pb/(206Pb matches the test substance well. As for feces, when (204Pb/(206Pb ratio is considered, there is no significant difference between feces-test substance pairs in medium and high dose group.The biological fractionation of lead isotopes in SD rats was observed. Moreover, there might be a threshold for the biological fractionation of lead isotopes which is depending on whole blood lead level. It is considered to be more reliable that we compared the isotope ratios of potential lead hazards with both blood and feces lead fingerprints especially for (204Pb/(206Pb ratio under high-dose exposure.

  2. Determination of toxic and essential elements in blood and milk from female subjects in a Lead contaminated community in Zamfara State, Nigeria

    International Nuclear Information System (INIS)

    Ojo, J.; Komolafe, O.; Obiajunwa, P.; Ogunba, B.; Adesanmi, C.; Kanoma, M.; Adedeji, S.; Horsvat, M.

    2011-01-01

    Occurrence of lead poisoning associated with gold mining and processing was reported around March 2010 in some communities of Zamfara State, leading to hundreds of fatalities, especially among children. We have evaluated the levels of lead and other elements (both toxic and essential) in human milk and whole blood samples obtained from 27 subjects at the village of Yargalma, in Anka Local Government Area of Zamfara State. Milk and blood samples were lyophilized at the Obafemi Awolowo University Teaching Hospital Complex, lIe-Ife, and were further sterilized by gamma irradiation (20 -30 kGy) at the National Radiation Centre, Abuja. Elemental analyses were carried out at the Josef Stefan Institute, Ljubljana, Slovenia for determination of Pb, Cd, As, Se, Zn and Cu by ICP-MS; and Hg by Direct Hg analyser. The significant contamination of the environment leading to the reported cases of Pb-poisoning in Zamfara gold mines have been confirmed by elevated levels of Pb measured in samples of blood and human milk. The levels of Pb in blood ranged from 7.9 - 86.8μg/dL (mean±SD: 55.6±19.6μg/dL) while levels of this toxic element in human milk ranged from 2 - 140 ng/ml (mean±SD: 45±37 ng/ml). These values, in asymptomatic subjects, are extremely high indeed. A number of interesting correlations between elemental levels in milk and blood of mothers, and the age of mother and period after birth have also been demonstrated. For instance Mothers age significantly correlates with blood Pb (confirming accumulation in bones which affect blood lead level in lactating mothers). On the other hand, Mother's age significantly correlate negatively with Blood Selenium. Levels of the essential element Zn in both blood and milk of mother significantly correlate negatively with the time elapsed after child delivery (Baby's Age) as is reported in literature. We hesitate to suggest that breast-feeding of babies be limited in these subjects, knowing the several other important nutrients

  3. Leo Tolstoy’s Anticlericalism in Its Context and Beyond: A Case against Churches and Clerics, Religious and Secular

    Directory of Open Access Journals (Sweden)

    Alexandre Christoyannopoulos

    2016-05-01

    Full Text Available In the last thirty years of his life, Leo Tolstoy wrote numerous books, essays and pamphlets expounding his newly-articulated views on violence, the state, the church, and on how to improve the human condition. Since then, these “Christian anarchist” views have often been dismissed as utopian or naive, and, despite inspiring many activists and intellectuals, often forgotten or ignored. Some of those views and arguments, however, arguably remain apposite today—and can in some cases be applied to broader phenomena than those he identified. This article focuses on one of the aspects of his Christian anarchist thought: his anticlericalism. The first Section recounts the evolution of Tolstoy’s views on religion and the church, and briefly describes Tolstoy’s peculiar metaphysics. The second outlines his main charges against the church, discusses some common objections to it, and considers the continuing relevance of his anticlericalism. The third seeks to secularise his anticlerical arguments by applying them beyond the church, against secular preachers and institutions, and does so by reflecting on the quality of debate in the contemporary public sphere, on the hypocritical distance between the morality preached by secular “clerics” and their practice, and on the steady process of ossification and betrayal which befalls secular political ideals. The article thus contributes to the literature firstly by summarising, discussing and reflecting upon the anticlericalism of a famous writer who also espoused controversial religious and political views; secondly by succinctly outlining his idiosyncratic metaphysics, including his peculiar reinterpretation of traditional Christian referents; and thirdly by applying the arguments that informed his criticisms of the church to a broader variety of religious and secular secular institutions.

  4. Kidney Mass Reduction Leads to l-Arginine Metabolism-Dependent Blood Pressure Increase in Mice.

    Science.gov (United States)

    Pillai, Samyuktha Muralidharan; Seebeck, Petra; Fingerhut, Ralph; Huang, Ji; Ming, Xiu-Fen; Yang, Zhihong; Verrey, François

    2018-02-25

    Uninephrectomy (UNX) is performed for various reasons, including kidney cancer or donation. Kidneys being the main site of l-arginine production in the body, we tested whether UNX mediated kidney mass reduction impacts l-arginine metabolism and thereby nitric oxide production and blood pressure regulation in mice. In a first series of experiments, we observed a significant increase in arterial blood pressure 8 days post-UNX in female and not in male mice. Further experimental series were performed in female mice, and the blood pressure increase was confirmed by telemetry. l-citrulline, that is used in the kidney to produce l-arginine, was elevated post-UNX as was also asymmetric dimethylarginine, an inhibitor of nitric oxide synthase that competes with l-arginine and is a marker for renal failure. Interestingly, the UNX-induced blood pressure increase was prevented by supplementation of the diet with 5% of the l-arginine precursor, l-citrulline. Because l-arginine is metabolized in the kidney and other peripheral tissues by arginase-2, we tested whether the lack of this metabolic pathway also compensates for decreased l-arginine production in the kidney and/or for local nitric oxide synthase inhibition and consecutive blood pressure increase. Indeed, upon uninephrectomy, arginase-2 knockout mice (Arg-2 -/- ) neither displayed an increase in asymmetric dimethylarginine and l-citrulline plasma levels nor a significant increase in blood pressure. UNX leads to a small increase in blood pressure that is prevented by l-citrulline supplementation or arginase deficiency, 2 measures that appear to compensate for the impact of kidney mass reduction on l-arginine metabolism. © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  5. Secular and religious: the intrinsic doubleness of analytical psychology and the hegemony of naturalism in the social sciences.

    Science.gov (United States)

    Main, Roderick

    2013-06-01

    In recent years a number of prominent social theorists, including Jürgen Habermas and Charles Taylor, have voiced concern about the hegemony of naturalistic, secular assumptions in the social sciences, and in their different ways have sought to address this by establishing greater parity between secular and religious perspectives. This paper suggests that C.G. Jung's analytical psychology, which hitherto has been largely ignored by social theory, may have something to contribute on this issue as it can be understood coherently both empirically, without reference to transcendent reality, and metaphysically, with reference to transcendent reality. It is argued that, despite his denials of any metaphysical intent, Jung does in fact engage in metaphysics and that together the empirical and metaphysical vectors of his thought result in a rich and distinctive double perspective. This dual secular and religious perspective can be seen as part of Jung's own critique of the hegemony of naturalism and secularism, which for Jung has profound social as well as clinical relevance. The concern and approach that Habermas and Taylor share with Jung on this issue may provide some grounds for increased dialogue between analytical psychology and the social sciences. © 2013, The Society of Analytical Psychology.

  6. Post-Newtonian templates for binary black-hole inspirals: the effect of the horizon fluxes and the secular change in the black-hole masses and spins

    Science.gov (United States)

    Isoyama, Soichiro; Nakano, Hiroyuki

    2018-01-01

    Black holes (BHs) in an inspiraling compact binary system absorb the gravitational-wave (GW) energy and angular-momentum fluxes across their event horizons and this leads to the secular change in their masses and spins during the inspiral phase. The goal of this paper is to present ready-to-use, 3.5 post-Newtonian (PN) template families for spinning, non-precessing, binary BH inspirals in quasicircular orbits, including the 2.5 PN and 3.5 PN horizon-flux contributions as well as the correction due to the secular change in the BH masses and spins through 3.5 PN order, respectively, in phase. We show that, for binary BHs observable by Advanced LIGO with high mass ratios (larger than  ∼10) and large aligned-spins (larger than  ∼ 0.7 ), the mismatch between the frequency-domain template with and without the horizon-flux contribution is typically above the 3% mark. For (supermassive) binary BHs observed by LISA, even a moderate mass-ratios and spins can produce a similar level of the mismatch. Meanwhile, the mismatch due to the secular time variations of the BH masses and spins is well below the 1% mark in both cases, hence this is truly negligible. We also point out that neglecting the cubic-in-spin, point-particle phase term at 3.5 PN order would deteriorate the effect of BH absorption in the template.

  7. Secular Trends in the Incidence of Dementia in a Multi-Ethnic Community.

    Science.gov (United States)

    Noble, James M; Schupf, Nicole; Manly, Jennifer J; Andrews, Howard; Tang, Ming-Xin; Mayeux, Richard

    2017-10-03

    Determination of secular trends in cognitive aging is important for prioritization of resources, services, and research in aging populations. Prior studies have identified declining dementia incidence associated with changes in cardiovascular risk factors and increased educational attainment. However, few studies have examined these factors in multi-ethnic cohorts. To identify secular trends in the incidence rate of dementia in an elderly population. Participants in this study were drawn from the Washington Heights-Inwood Columbia Aging Project, a multi-ethnic cohort study of northern Manhattan residents aged 65 years and older. Cox proportional hazards models were used to examine differences in the incidence of dementia in cohorts recruited in 1992 and 1999, with age at dementia or age at last follow-up visit as the "time-to-event" variable. Overall, there was a 41% reduction in the hazard ratio for dementia among participants in the 1999 cohort compared with those in the 1992 cohort, adjusting for age, sex, race, and baseline memory complaints (HR = 0.59). The reduction in incidence was greatest among non-Hispanic Whites and African-Americans and lowest among Hispanic participants (HRs = 0.60, 0.52 and 0.64, respectively), and was associated with increases in level of educational attainment, especially among African-Americans. Reduction in incidence of dementia was also greater among persons 75 years or older than among younger participants (HR = 0.52 versus HR = 0.69). Our results support previous findings that secular trends in dementia incidence are changing, including in aging minority populations.

  8. Comparative analysis of concentrations of lead, cadmium and mercury in cord blood, maternal blood, and breast milk, as well as persistent chlorinated hydrocarbons in maternal milk samples from Germany and Iran

    International Nuclear Information System (INIS)

    Javanmardi, F.

    2001-01-01

    The concentration of the heavy metals lead, cadmium and mercury in cord blood, maternal blood and breast milk has been studied. Lead and cadmium were analyzed by atomic absorption spectrometry. Mercury was determined using the flow-injection hydride technique. According to the concentrations of heavy metals and chlorinated hydrocarbons we ascertained for the region of Rendsburg, the toxic risk for infants relative to the consumption of contaminated maternal milk can be viewed as very slight. (orig.) [de

  9. Neo-Hindu Fundamentalism Challenging the Secular and Pluralistic Indian State

    Directory of Open Access Journals (Sweden)

    Gino Battaglia

    2017-10-01

    Full Text Available Secularism seems to require separation between religion and State. Regarding India, it would be better to speak of ‘equidistance’ between State and religious denominations. Nonetheless a ‘balanced treatment’ towards the religions leaves the question open as to what form that equidistance should take. This is the reason of some contradictions in today’s Indian social and political life. It is likely that without the Moghul and British domination Hinduism would not have acquired a militant identity. It was the ‘epiphany’ of well-armed, powerful ‘Others’ (Muslim, Christian or secular which generated frustration and fear to such an extent that a religious nationalism (Hindutva was born. Nehru and the Left of the Congress Party leadership thought that modernity would overcome religion, which is a remnant of the past. They were confident that a political culture based on pluralism and tolerance would become the foundations of the new society. This is exactly what Hindu Nationalism takes issue with: the ‘pseudo-seculars’ project of building the national identity without Hinduism or against Hinduism. Hindutva asserts that Hinduism is the basis of the Indian civilization. The Hindu ethos is the soul of the nation.

  10. Levels and source apportionment of children's lead exposure: Could urinary lead be used to identify the levels and sources of children's lead pollution?

    International Nuclear Information System (INIS)

    Cao, Suzhen; Duan, Xiaoli; Zhao, Xiuge; Wang, Beibei; Ma, Jin; Fan, Delong; Sun, Chengye; He, Bin; Wei, Fusheng; Jiang, Guibin

    2015-01-01

    As a highly toxic heavy metal, the pollution and exposure risks of lead are of widespread concern for human health. However, the collection of blood samples for use as an indicator of lead pollution is not always feasible in most cohort or longitudinal studies, especially those involving children health. To evaluate the potential use of urinary lead as an indicator of exposure levels and source apportionment, accompanying with environmental media samples, lead concentrations and isotopic measurements (expressed as 207 Pb/ 206 Pb, 208 Pb/ 206 Pb and 204 Pb/ 206 Pb) were investigated and compared between blood and urine from children living in the vicinities of a typical coking plant and lead-acid battery factory. The results showed urinary lead might not be a preferable proxy for estimating blood lead levels. Fortunately, urinary lead isotopic measurements could be used as an alternative for identifying the sources of children's lead exposure, which coincided well with the blood lead isotope ratio analysis. - Highlights: • Pb isotopes of environmental media and children's blood and urine were analyzed. • Pb exposure and pollution source were studied in lead-acid battery and coking areas. • Pb isotope ratios in blood and urine were similar to those of food, water and PM. • Urine Pb level may not be used as a proxy for indicating the lead levels in blood. • Urine Pb isotope ratios is an alternative to identify source and exposure pathways. - Urinary lead is not a preferable proxy to estimate blood lead level, but urinary lead isotope ratios could be an alternative for identifying the sources of lead exposure in children

  11. Blood lead and cadmium levels in preschool children and associated risk factors in São Paulo, Brazil.

    Science.gov (United States)

    Olympio, Kelly Polido Kaneshiro; Silva, Júlia Prestes da Rocha; Silva, Agnes Soares da; Souza, Vanessa Cristina de Oliveira; Buzalaf, Marília Afonso Rabelo; Barbosa, Fernando; Cardoso, Maria Regina Alves

    2018-05-18

    In Brazil, there are scarce data on lead (Pb) and cadmium (Cd) contamination, especially for more vulnerable populations such as preschool children. In this paper, we answer two questions: (1) What are the exposure levels of lead and cadmium in preschool children, in Sao Paulo, Brazil? and (2) What are the risk factors associated with this exposure? This cross-sectional study included 50 day care centers (DCCs), totaling 2463 children aged 1-4 years. Venous blood samples were analyzed by ICP-MS. Questionnaires were administered to the parents. Multiple logistic regression models were used to identify associations between blood lead levels (BLLs) and blood cadmium levels (BCLs) and potential risk factors. The geometric mean for BLLs was 2.16 μg/dL (95% CI: 2.10-2.22 μg/dL), and the 97.5th percentile was 13.9 μg/dL (95% CI: 10.0-17.3 μg/dL). For cadmium exposure, the geometric mean for BCLs was 0.48 μg/L (95% CI: 0.47-0.50 μg/L), and the 95th percentile was 2.57 μg/L (95% CI: 2.26-2.75 μg/L). The DCCs' geographic region was associated with high BLLs and BCLs, indicating hot spots for lead and cadmium exposures. In addition, it was found that the higher the vehicles flow, the higher were the BLLs in children. Red lead in household gates was also an important risk factor for lead exposure. Comparing these results with the findings of the Fourth National Report on Human Exposure to Environmental Chemicals by CDC-2013, it was found that in Brazilian preschool children the BLLs are almost three times higher (97.5th percentile) and the BCLs are almost twelve times higher (95th percentile) than those in U.S. children. This information is essential to formulate public health policies. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Effects of Antipsychotics on Secular Mortality Trends in Patients With Alzheimer's Disease

    DEFF Research Database (Denmark)

    Nielsen, René Ernst; Valentin, Jan B; Lolk, Annette

    2018-01-01

    OBJECTIVE: To investigate secular changes in mortality rates between patients with Alzheimer's disease (AD) and the general population as well as changes in antipsychotic drug treatment and the association between drug treatment and mortality in patients with AD in Denmark during a 12-year study...

  13. A Multi-Disciplinary Inquiry of Secular and Christian Approaches to Sex Education

    Science.gov (United States)

    Yu, Chong Ho; Lee, Hyun Seo

    2018-01-01

    Secular scholars have criticized Christian education and counseling on sex as restrictive, ineffective, and outdated. The authors of the current study explored both common non-Christian and Christian approaches to human sexuality with reference to overarching domains of religion, philosophy, psychology, sociology, and anthropology. Secular…

  14. Explanation of observable secular variations of gravity and alternative methods of determination of drift of the center of mass of the Earth

    Science.gov (United States)

    Barkin, Yury

    2010-05-01

    the mantle and makes 19.32 % of mass of full the Earth. At displacement of the core relatively to the viscous-elastic mantle its superfluous mass causes observable drift of the center of mass, and also leads to changes of a gravity on the surface of the planet. Except for it the gravitational attraction of a displaced core causes deformations of all layers of the mantle, including a superficial layer. The deformed mantle produses some additional gravitational potential which gives the additional contribution to value of a gravity. Thus, noted factors lead to a secular variation of a gravity which is described by the simple formula [2]: dot g = 2gμmc-(1- h-2- 0.5k-2)ρdot-sin?, μmc = 0.1932m ⊙, g = 9.82022 m -s2 m ⊙ r⊙ (1) Here μmc = 0.1932m⊙ is a superflous mass of the Earth core in the masses of the Earth m⊙. g is an acceleration of free falling. k-2 and h-2 are Love numbers of the order (-2). ρdot is a velocity of the secular drift of the center of mass of the core relatively to the center of mass of the mantle. ?is an angle between dirtection to the pole P (in a direction to which the core of the Earth or its center of mass drifts), and direction to gravimetric station. For rough estimates of gravimetric effects as pole P the North Pole of the Earth has been accepted. Thus ? = ?-2 - φis a co-latitude. At more exact description of the core drift (or the center of mass drift) an angle? is determined by formula: cos? = cosφP cosφcos(λP - λ) + sinφP sinφ, where φP and λP is a latitude and longitude of pole P; φ and λ is a latitude and longitude of station. The Love numbers of the order (-2) in first have been evaluated in the paper [4] and have small values: k-2=-0.005004 and h-2=0.0062154. Approximately we can put ρdot m⊙ = μmcṙC, where ṙC is a velocity of the drift of the center of mass of the Earth. Then, neglecting small effects, for a variation of gravity (1) we obtain a following expression: ? r = 2ṙCg cos

  15. Religious, Secular, and Spiritual Identities Convergence: Introduction to the Special Issue

    Science.gov (United States)

    Small, Jenny L.; Bowman, Nicholas A.

    2018-01-01

    The purpose of this special issue is to share the best research, theory, practice, and perspectives from presenters at the 2017 Religious, Secular, and Spiritual Identities Convergence conference, alongside the new writing of scholars and practitioners who were inspired by the themes of the conference. Readers will have access both to the best of…

  16. The European Court of Human Rights, Secular Education and Public Schooling

    Science.gov (United States)

    Arthur, James; Holdsworth, Michael

    2012-01-01

    Since 9/11 the European Court of Human Rights (the European Court) has raised anew the question of the relationship between religion and public education. In its reasoning, the European Court has had to consider competing normative accounts of the secular, either to accept or deny claims to religious liberty within Europe's public education…

  17. Secular Trends in the Physical Fitness of American Youth, Young Adults and Army Recruits

    National Research Council Canada - National Science Library

    Knapik, Joseph

    2004-01-01

    This paper reviews the literature and existing databases for information on secular trends in the physical fitness of young Americans and describes changes in fitness during Basic Combat Training (BCT...

  18. Epidemiologic Characteristics of Children with Blood Lead Levels ≥45 μg/dL.

    Science.gov (United States)

    Keller, Brett; Faciano, Andrew; Tsega, Adey; Ehrlich, Jacqueline

    2017-01-01

    To identify risk factors and describe outcomes for children newly identified with blood lead levels (BLLs) ≥45 µg/dL in New York City (NYC) during 2004-2010 to promote timely identification as well as inform clinical practice and public health policy. Inclusion criteria were residence in NYC and an elevated confirmatory venous test within 2 weeks of the initial BLL ≥45 µg/dL. Data collected during case coordination of these children were linked with blood testing data and home inspection reports. Children with BLLs ≥45 µg/dL also were compared with the general population of children younger than 18 years of age in NYC. A total of 145 children lead poisoning has declined in the US, severe cases still occur. Physicians should be especially vigilant in certain at-risk populations including children who eat paint chips or soil, spend time outside the US (particularly in Pakistan), use imported products, or have developmental delays or sickle cell disease. Published by Elsevier Inc.

  19. Re-evaluation of blood mercury, lead and cadmium concentrations in the Inuit population of Nunavik (Québec): a cross-sectional study

    Science.gov (United States)

    Fontaine, Julie; Dewailly, Éric; Benedetti, Jean-Louis; Pereg, Daria; Ayotte, Pierre; Déry, Serge

    2008-01-01

    Background Arctic populations are exposed to mercury, lead and cadmium through their traditional diet. Studies have however shown that cadmium exposure is most often attributable to tobacco smoking. The aim of this study is to examine the trends in mercury, lead and cadmium exposure between 1992 and 2004 in the Inuit population of Nunavik (Northern Québec, Canada) using the data obtained from two broad scale health surveys, and to identify sources of exposure in 2004. Methods In 2004, 917 adults aged between 18 and 74 were recruited in the 14 communities of Nunavik to participate to a broad scale health survey. Blood samples were collected and analysed for metals by inductively coupled plasma mass spectrometry, and dietary and life-style characteristics were documented by questionnaires. Results were compared with data obtained in 1992, where 492 people were recruited for a similar survey in the same population. Results Mean blood concentration of mercury was 51.2 nmol/L, which represent a 32% decrease (p < 0.001) between 1992 and 2004. Mercury blood concentrations were mainly explained by age (partial r2 = 0.20; p < 0.0001), and the most important source of exposure to mercury was marine mammal meat consumption (partial r2 = 0.04; p < 0.0001). In 2004, mean blood concentration of lead was 0.19 μmol/L and showed a 55% decrease since 1992. No strong associations were observed with any dietary source, and lead concentrations were mainly explained by age (partial r2 = 0.20.; p < 0.001). Blood cadmium concentrations showed a 22% decrease (p < 0.001) between 1992 and 2004. Once stratified according to tobacco use, means varied between 5.3 nmol/L in never-smokers and 40.4 nmol/L in smokers. Blood cadmium concentrations were mainly associated with tobacco smoking (partial r2 = 0.56; p < 0.0001), while consumption of caribou liver and kidney remain a minor source of cadmium exposure among never-smokers. Conclusion Important decreases in mercury, lead and cadmium exposure

  20. Spatial patterns and secular trends in human leishmaniasis incidence in Morocco between 2003 and 2013.

    Science.gov (United States)

    Sadeq, Mina

    2016-05-11

    Few studies on spatial patterns or secular trends in human leishmanias have been conducted in Morocco. This study aimed to examine spatial patterns and trends associated with the human leishmaniasis incidence rate (HLIR) at the province/prefecture level between 2003 and 2013 in Morocco. Only the available published country data on the HLIR between 2003 and 2013, from the open access files of the Ministry of Health, were used. Secular trends were examined using Kendall's rank correlation. An exploratory spatial data analysis was also conducted to examine the spatial autocorrelation (Global Moran's I and local indicator of spatial association [LISA]), and spatial diffusion at the province/prefecture level. The influence of various covariates (poverty rate, vulnerability rate, population density, and urbanization) on the HLIR was tested via spatial regression (ordinary least squares regression). At the country level, no secular variation was observed. Poisson annual incidence rate estimates were 13 per 100 000 population (95 % CI = 12.9-13.1) for cutaneous leishmaniasis (CL) and 0.4 per 100 000 population (95 % CI = 0.4-0.5) for visceral leishmaniasis (VL). The available data on HLIR were based on combined CL and VL cases, however, as the CL cases totally outnumbered the VL ones, HLIR may be considered as CL incidence rate. At the provincial level, a secular increase in the incidence rate was observed in Al Hoceima (P = 0.008), Taounate (P = 0.04), Larache (P = 0.002), Tétouan (P = 0.0003), Khenifra (P = 0.008), Meknes (P = 0.03), and El Kelaa (P = 0.0007), whereas a secular decrease was observed only in the Chichaoua province (P = 0.006). Even though increased or decreased rate was evident in these provinces, none of them showed clustering of leishmaniasis incidence. Significant spatial clusters of high leishmaniasis incidence were located in the northeastern part of Morocco, while spatial clusters of low leishmaniasis

  1. Levels and source apportionment of children's lead exposure: could urinary lead be used to identify the levels and sources of children's lead pollution?

    Science.gov (United States)

    Cao, Suzhen; Duan, Xiaoli; Zhao, Xiuge; Wang, Beibei; Ma, Jin; Fan, Delong; Sun, Chengye; He, Bin; Wei, Fusheng; Jiang, Guibin

    2015-04-01

    As a highly toxic heavy metal, the pollution and exposure risks of lead are of widespread concern for human health. However, the collection of blood samples for use as an indicator of lead pollution is not always feasible in most cohort or longitudinal studies, especially those involving children health. To evaluate the potential use of urinary lead as an indicator of exposure levels and source apportionment, accompanying with environmental media samples, lead concentrations and isotopic measurements (expressed as (207)Pb/(206)Pb, (208)Pb/(206)Pb and (204)Pb/(206)Pb) were investigated and compared between blood and urine from children living in the vicinities of a typical coking plant and lead-acid battery factory. The results showed urinary lead might not be a preferable proxy for estimating blood lead levels. Fortunately, urinary lead isotopic measurements could be used as an alternative for identifying the sources of children's lead exposure, which coincided well with the blood lead isotope ratio analysis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. The steady part of the secular variation of the Earth's magnetic field

    Science.gov (United States)

    Bloxham, Jeremy

    1992-01-01

    The secular variation of the Earth's magnetic field results from the effects of magnetic induction in the fluid outer core and from the effects of magnetic diffusion in the core and the mantle. Adequate observations to map the magnetic field at the core-mantle boundary extend back over three centuries, providing a model of the secular variation at the core-mantle boundary. Here we consider how best to analyze this time-dependent part of the field. To calculate steady core flow over long time periods, we introduce an adaptation of our earlier method of calculating the flow in order to achieve greater numerical stability. We perform this procedure for the periods 1840-1990 and 1690-1840 and find that well over 90 percent of the variance of the time-dependent field can be explained by simple steady core flow. The core flows obtained for the two intervals are broadly similar to each other and to flows determined over much shorter recent intervals.

  3. Examination of US puberty-timing data from 1940 to 1994 for secular trends

    DEFF Research Database (Denmark)

    Euling, Susan Y; Herman-Giddens, Marcia E; Lee, Peter A

    2008-01-01

    or girls. A majority of the panelists agreed that data are sufficient to suggest a trend toward an earlier breast development onset and menarche in girls but not for other female pubertal markers. A minority of panelists concluded that the current data on girls' puberty timing for any marker...... are insufficient. Almost all panelists concluded, on the basis of few studies and reliability issues of some male puberty markers, that current data for boys are insufficient to evaluate secular trends in male pubertal development. The panel agreed that altered puberty timing should be considered an adverse effect......Whether children, especially girls, are entering and progressing through puberty earlier today than in the mid-1900s has been debated. Secular trend analysis, based on available data, is limited by data comparability among studies in different populations, in different periods of time, and using...

  4. Debating Modernity as Secular Religion: Hans Kelsen’s futile exchange with Eric Voegelin

    DEFF Research Database (Denmark)

    Thomassen, Bjørn

    2014-01-01

    This article reviews the mysterious and recently published last book by Hans Kelsen, “Secular Religion. A Polemic Against the Misinterpretation of Modern Social Philosophy, Science and Politics as ‘New Religions’”, contextualizing it with reference to the little known dialogue between Hans Kelsen...... and Eric Voegelin. The confrontation between Kelsen and Voegelin, two of the most illustrious émigré scholars who found in America their new home, is important to revisit because it touches upon several axes of debate of crucial importance to postwar intellectual history: the religion/secularity debate......, the positivist/anti-positivist debates, and the controversy that also led to the famous Voegelin/Arendt debate: how to read the horrors of totalitarianism into a historical trajectory of modernity. Although the Kelsen/Voegelin exchange ended in failure and bitterness its substance matter goes to the heart...

  5. Lead levels in the workers blood at the Toluca bus terminal.; Niveles de plomo en sangre de los trabajadores de la terminal de autobuses de Toluca.

    Energy Technology Data Exchange (ETDEWEB)

    Gomez H, S P; Garcia G, G

    1998-06-01

    The study was carried out in order to detect the levels of lead in blood in exposed workers to the lead in their place of work, in the Toluca bus terminal. The measurement of the levels of lead in blood was carried out in a sample of 31 people of 60 workers for atomic absorption spectrometry. The lead is a general protoplasmic poison that is accumulative and produce great variety of symptoms, the lead could be absorbed inside the body for ingestion, inhalation and through the skin. Organic compounds of the lead as tetraethyl lead, penetrate the cutaneous barrier quickly. From the beginning the personal habits were evaluated, hygienic, nutritious and the environmental conditions by means of a questionnaire. The levels of lead in opposing blood, they were below them you limit permissible for personal exposed, published by the WHO. (Author).

  6. Toxicants in folk remedies: Implications of elevated blood lead in an American-born infant due to imported diaper powder

    Science.gov (United States)

    Karwowski, Mateusz P.; Morman, Suzette A.; Plumlee, Geoffrey S.; Law, Terence; Kellogg, Mark; Woolf, Alan D.

    2016-01-01

    Though most childhood lead exposure in the USA results from ingestion of lead-based paint dust, non-paint sources are increasingly implicated. We present interdisciplinary findings from and policy implications of a case of elevated blood lead (13–18 mcg/dL, reference level Malaysian folk diaper powder. Analyses showed the powder contains 62 % lead by weight (primarily lead oxide) and elevated antimony [1000 parts per million (ppm)], arsenic (55 ppm), bismuth (110 ppm), and thallium (31 ppm). These metals are highly bioaccessible in simulated gastric fluids, but only slightly bioaccessible in simulated lung fluids and simulated urine, suggesting that the primary lead exposure routes were ingestion via hand-mouth transmission and ingestion of inhaled dusts cleared from the respiratory tract. Four weeks after discontinuing use of the powder, the infant’s venous blood lead level was 8 mcg/dL. Unregulated, imported folk remedies can be a source of toxicant exposure. Additional research on import policy, product regulation, public health surveillance, and culturally sensitive risk communication is needed to develop efficacious risk reduction strategies in the USA. The more widespread use of contaminated folk remedies in the countries from which they originate is a substantial concern.

  7. Relationships of maternal blood lead and disorders of pregnancy to neonatal birthweight.

    Science.gov (United States)

    Kaul, P P; Srivastava, R; Srivastava, S P; Kamboj, M; Chand, S

    2002-12-01

    Transient complications of pregnancy (anemia, toxemia, proteinuria, arterial hypertension and hyperemesis) were studied in pregnant women from the general population reporting to local hospitals. Comparison of blood lead levels (PbB) was made between women with normal pregnancies and those with complications. Significantly higher PbB were found in women with pregnancy complications as compared to those with normal pregnancies. Increments in the PbB levels were accompanied by statistically significant decrements in neonate birthweights. Complications of pregnancy may be induced by higher PbB and may also compound the adverse effects of decrements of neonate birthweights

  8. Contemplative Science and Secular Ethics

    Directory of Open Access Journals (Sweden)

    Brendan Ozawa-de Silva

    2016-08-01

    Full Text Available This article argues that the emerging project of contemplative science will be best served if it is informed by two perspectives. First, attention should be paid not only to non-analytical and/or mindfulness-based practices, but to a fuller range of contemplative practices, including analytical styles of meditation. Second, the issue of ethics must be addressed as a framework within which to understand contemplative practice: both theoretically in order to understand better the practices themselves and the traditions they come from, and practically in order to understand the ways in which contemplative practices are deployed in contemporary societies. The Tibetan Buddhist Lojong (blo sbyong tradition and secularized practices derived from it, which are now an area of study in contemplative science, are examined as a kind of case study in order to make these two points and illustrate their importance and relevance for the future of this emerging field.

  9. Between Christianity and secularity: counselling and psychotherapy provision in Scotland

    OpenAIRE

    Bondi, Liz

    2013-01-01

    Counselling and psychotherapy services have become increasingly prominent within modern urban welfare. Although often perceived to be intrinsically secular, since psychoanalytic thinking and practice arrived in Scotland it has been shaped by the Christian culture it encountered. Early Scottish-born contributors to psychoanalytic theory, including Ian Suttie and W.R.D. Fairbairn, reframed Freud’s ideas in ways that incorporated Scottish Presbyterian understandings of what it is to be human. A ...

  10. Secular trends in lipid-lowering treatment and lipid levels after a first acute myocardial infarction

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    Lena Björck

    2008-01-01

    Full Text Available Lena Björck1, Catharina Welin2, Annika Rosengren11Department of medicine, Sahlgrenska University Hospital/Östra, Göteborg, Sweden; 2Institute of Health and Care Sciences, the Sahlgrenska Academy at Göteborg University, Göteborg, SwedenBackground: The beneficial effects of statins were unequivocally demonstrated in the Scandinavian Simvastatin Survival Study (4S in 1994, leading to an increase in the use of lipid-lowering drugs. However, to what extent this translates into serum cholesterol levels in a real-life setting has not been systematically investigated.Objective: To estimate secular trends from 1994 to 2002 in blood lipid levels among unselected younger patients after a first acute myocardial infarction (AMI.Method: Descriptive single centre study using consecutive data collection in 781 patients (aged <65 years hospitalized with a first AMI during the period 1994–2002.Results: From 1994–2002, the use of lipid-lowering drugs increased from 10% to 94% for men and from 23% to 90% for women. In 1994, the mean serum cholesterol levels were 6.53 mmol/l in men and 6.32 mmol/l in women, decreasing to 4.31 mmol/l and 5.13 mmol/l in men and women, respectively, in 2002. Still, only 56% of the men and 35% of the women had total serum cholesterol levels <4.5 mmol/l in 2002.Conclusion: Despite a marked increase in lipid-lowering drug treatment in which there was an increase from about 10% in 1994 to more than 90% in 2002, current target levels of <4.5 mmol/l for serum cholesterol were not achieved in a significant proportion of post-AMI patients.Keywords: lipid levels, lipid-lowering medication, myocardial infarction, risk factors

  11. Biological fractionation of lead isotopes in Sprague-Dawley rats lead poisoned via the respiratory tract.

    Science.gov (United States)

    Wu, Jing; Liu, Duojian; Xie, Qing; Wang, Jingyu

    2012-01-01

    It was considered that lead isotope ratios did not change during physical, chemical, or biological processes. Thus, lead isotope ratios have been used as fingerprints to identify possible lead sources. However, recent evidence has shown that the lead isotope ratios among different biological samples in human are not always identical from its lead origins in vitro. An animal experiment was conducted to explore the biological fractionation of lead isotopes in biological systems. 24 male Sprague-Dawley (SD) rats were divided into groups that received acute lead exposure (0, 0.02, 0.2, or 2 mg/kg body weight of lead acetate) via the respiratory route every day for 5 days. Biological samples (i.e., blood, urine, and feces) were collected for comparison with the lead acetate (test substance) and the low-lead animal feed (diet) administered to the rats. The lead isotope ratios were determined by inductively coupled plasma mass spectrometry (ICP-MS). There are significant differences (pblood, urine, and feces. Moreover, a nonlinear relationship between the blood lead concentration and the blood lead isotope ratios was observed. There is also a threshold effect to the fractionation function. Only the blood isotope ratio of (204)Pb/(206)Pb matches the test substance well. As for feces, when (204)Pb/(206)Pb ratio is considered, there is no significant difference between feces-test substance pairs in medium and high dose group. The biological fractionation of lead isotopes in SD rats was observed. Moreover, there might be a threshold for the biological fractionation of lead isotopes which is depending on whole blood lead level. It is considered to be more reliable that we compared the isotope ratios of potential lead hazards with both blood and feces lead fingerprints especially for (204)Pb/(206)Pb ratio under high-dose exposure.

  12. Defining and Distinguishing Secular and Religious Terrorism

    Directory of Open Access Journals (Sweden)

    Heather S. Gregg

    2014-04-01

    Full Text Available Religious terrorism is typically characterised as acts of unrestrained, irrational and indiscriminant violence, thus offering few if any policy options for counterterrorism measures. This assumption about religious terrorism stems from two challenges in the literature: disproportionate attention to apocalyptic terrorism, and a lack of distinction between religious terrorism and its secular counterpart. This article, therefore, aims to do four things: define and differentiate religiously motivated terrorism from traditional terrorism; investigate three goals of religious terrorism (fomenting the apocalypse, creating a religious government, and establishing a religiously pure state; consider the role of leadership and target selection of religious terrorists; and, finally, suggest a range of counterterrorism strategies based on these observations.

  13. Variaciones seculares de período en las RR Lyrae de ω~Centauri

    Science.gov (United States)

    Marraco, H. G.; Milesi, G. E.

    Utilizando 689 observaciones de 35 estrellas RR Lyrae del cúmulo globular ω Centauri hemos obtenido nuevas determinaciones de sus períodos y sus correspondientes variaciones seculares. Las observaciones fueron obtenidas de la literatura con la excepción de un grupo 66 determinaciones que se presentan por vez primera aquí. Utilizando el parámetro testigo σ descripto en Marraco & Muzzio (Publ. Astron. Soc. Pacific 92, 700, 1980), hemos realizado un ajuste bidimensional en P y β (donde β es la variación secular del período). Con este fin la totalidad de las 689 observaciones fueron llevadas a un sistema fotométrico común. Para esto se realizó un cuidadoso análisis de los numerosos errores en la identificación de las estrellas de las series de comparación. Los resultados de los ajustes bidimensionales fueron analizados utilizando técnicas de procesamiento de imágenes. Con este fin el parámetro de ajuste σ fue representado como función de P y β. En las imágenes resultantes se buscaron los mínimos y al menor de ellos se lo aceptó como período instantáneo verdadero y su variación secular β. La determinación precisa de cada parámetro se realizó mediante ajuste de gaussianas y se determinaron sus errores. A modo de ejemplo la variable #8 fue analizada en una matriz de 501 × 501 elementos representando el parámetro σ para valores comprendidos entre 0,521034 son P = 0,5212859±0,0000001 días y β 14,012±,010×10-10 días/día respectivamente. Con estos valores el parámetro testigo resulta σ= 0,127 . Si no se tiene en cuenta la variación secular del período y se busca aquél de mejor ajuste para β = 0, se obtiene P = 0,5212960 días, pero entonces el parámetro de ajuste resulta tan alto como σ = 0,23 .

  14. Reference frame access under the effects of great earthquakes: a least squares collocation approach for non-secular post-seismic evolution

    Science.gov (United States)

    Gómez, D. D.; Piñón, D. A.; Smalley, R.; Bevis, M.; Cimbaro, S. R.; Lenzano, L. E.; Barón, J.

    2016-03-01

    The 2010, (Mw 8.8) Maule, Chile, earthquake produced large co-seismic displacements and non-secular, post-seismic deformation, within latitudes 28°S-40°S extending from the Pacific to the Atlantic oceans. Although these effects are easily resolvable by fitting geodetic extended trajectory models (ETM) to continuous GPS (CGPS) time series, the co- and post-seismic deformation cannot be determined at locations without CGPS (e.g., on passive geodetic benchmarks). To estimate the trajectories of passive geodetic benchmarks, we used CGPS time series to fit an ETM that includes the secular South American plate motion and plate boundary deformation, the co-seismic discontinuity, and the non-secular, logarithmic post-seismic transient produced by the earthquake in the Posiciones Geodésicas Argentinas 2007 (POSGAR07) reference frame (RF). We then used least squares collocation (LSC) to model both the background secular inter-seismic and the non-secular post-seismic components of the ETM at the locations without CGPS. We tested the LSC modeled trajectories using campaign and CGPS data that was not used to generate the model and found standard deviations (95 % confidence level) for position estimates for the north and east components of 3.8 and 5.5 mm, respectively, indicating that the model predicts the post-seismic deformation field very well. Finally, we added the co-seismic displacement field, estimated using an elastic finite element model. The final, trajectory model allows accessing the POSGAR07 RF using post-Maule earthquake coordinates within 5 cm for ˜ 91 % of the passive test benchmarks.

  15. THE CRISIS OF THE MODERN MAN IN THE CONTEXT OF SECULARIZATION AND A POSSIBLE ANSWER FROM A TRANSDISCIPLINARY PERSPECTIVE

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    MUSTEA ANCA

    2010-09-01

    Full Text Available The human being is permanently in search for meaning: the meaning of his life, the meaning ofdaily events, and most of all, the meaning of its sufferance. The process of secularization affects themeaning making process by eliminating the spiritual dimension of man, and the consequences, asemphasized by Mircea Eliade, Carl Gustav Jung or Viktor Frankl are disastrous, all leading to thealienation of man and the possibility of self destruction. The transdisciplinary approach isdiscussed here in relation to the possibility of recuperating this meaning. The consideration of aspiritual dimension of human, as well as of democracy might be a viable solution against the“existential vacuum” due to the loss of meaning.

  16. Associations of blood lead, cadmium, and mercury with estimated glomerular filtration rate in the Korean general population: Analysis of 2008-2010 Korean National Health and Nutrition Examination Survey data

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yangho [Department of Occupational and Environmental Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan (Korea, Republic of); Lee, Byung-Kook, E-mail: bklee@sch.ac.kr [Institute of Environmental and Occupational Medicine, Soonchunhyang University 646 Eupnae-ri, Shinchang-myun, Asan-si, Choongnam 336-745 (Korea, Republic of)

    2012-10-15

    Introduction: The objective of this study was to evaluate associations between blood lead, cadmium, and mercury levels with estimated glomerular filtration rate in a general population of South Korean adults. Methods: This was a cross-sectional study based on data obtained in the Korean National Health and Nutrition Examination Survey (KNHANES) (2008-2010). The final analytical sample consisted of 5924 participants. Estimated glomerular filtration rate (eGFR) was calculated using the MDRD Study equation as an indicator of glomerular function. Results: In multiple linear regression analysis of log2-transformed blood lead as a continuous variable on eGFR, after adjusting for covariates including cadmium and mercury, the difference in eGFR levels associated with doubling of blood lead were -2.624 mL/min per 1.73 m Superscript-Two (95% CI: -3.803 to -1.445). In multiple linear regression analysis using quartiles of blood lead as the independent variable, the difference in eGFR levels comparing participants in the highest versus the lowest quartiles of blood lead was -3.835 mL/min per 1.73 m Superscript-Two (95% CI: -5.730 to -1.939). In a multiple linear regression analysis using blood cadmium and mercury, as continuous or categorical variables, as independent variables, neither metal was a significant predictor of eGFR. Odds ratios (ORs) and 95% CI values for reduced eGFR calculated for log2-transformed blood metals and quartiles of the three metals showed similar trends after adjustment for covariates. Discussion: In this large, representative sample of South Korean adults, elevated blood lead level was consistently associated with lower eGFR levels and with the prevalence of reduced eGFR even in blood lead levels below 10 {mu}g/dL. In conclusion, elevated blood lead level was associated with lower eGFR in a Korean general population, supporting the role of lead as a risk factor for chronic kidney disease.

  17. Tendencia secular da amamentacao no Brasil

    Directory of Open Access Journals (Sweden)

    Sonia Isoyama Venancio

    2013-12-01

    Full Text Available Com o objetivo de documentar a tendência secular da amamentação no Brasil, foram reanalisadas as bases de dados de sete pesquisas nacionais realizadas de 1975 a 2008. Para obter dados comparáveis entre os diferentes inquéritos, foram analisadas as mesmas faixas etárias e indicadores, e utilizadas as mesmas técnicas estatísticas. A duração mediana da amamentação aumentou de 2,5 para 11,3 meses e a prevalência da amamentação exclusiva em menores de seis meses passou de 3,1% para 41,0% no período. Os resultados apontam importantes desafios no sentido de acelerar o ritmo de crescimento dessa prática no País, rumo às recomendações internacionais.

  18. Blood morphology and the levels of selected cytokines related to hematopoiesis in occupational short-term exposure to lead

    International Nuclear Information System (INIS)

    Dobrakowski, Michał; Boroń, Marta; Czuba, Zenon P.; Birkner, Ewa; Chwalba, Artur; Hudziec, Edyta; Kasperczyk, Sławomir

    2016-01-01

    The aim of the study was to investigate the influence of a short-term exposure to lead on the blood morphology and the levels of selected cytokines related to hematopoiesis in occupationally exposed workers. The study population included 37 males occupationally exposed to lead for 36 to 44 days. Their blood lead level raised from 10.7 ± 7.67 μg/dl at baseline to the level of 49.1 ± 14.1 μg/dl at the end of the study. The level of hemoglobin and values of MCH and MCHC were decreased due to a short-term exposure to lead by 2%, 2%, and 1%, respectively. The counts of WBC, LYM, and MXD increased significantly by 5%, 7%, and 35%. Similarly, the count of PLT increased by 7%, while PDW, MPV, and P-LCR decreased by 6%, 3%, and 9%, respectively. The levels of IL-7, G-CSF, HGF, PDGF AB/BB, SCF, and PECAM-1, decreased significantly by 30%, 33%, 8%, 30%, 25%, and 20%, respectively. A short-term occupational exposure to lead results in a decreased hemoglobin level and increased counts of WBC and PLT. Changes in counts and proportions of different types of leukocytes and decreased values of PLT indices, such as PDW, MPV, and P-LCR, due to the subacute lead-exposure may be associated with lead-induced decreased levels of cytokines related to hematopoiesis, including SCF, G-CSF, IL-7, and PDGF. - Highlights: • Subacute exposure to lead results in a decreased hemoglobin level. • Subacute exposure to lead results in increased counts of WBC and PLT. • Subacute exposure to lead decreases the levels of SCF, G-CSF, IL-7, and PDGF.

  19. Blood morphology and the levels of selected cytokines related to hematopoiesis in occupational short-term exposure to lead

    Energy Technology Data Exchange (ETDEWEB)

    Dobrakowski, Michał, E-mail: michal.dobrakowski@poczta.fm [Department of Biochemistry, School of Medicine with the Division of Dentistry, Medical University of Silesia, ul. Jordana 19, 41-808 Zabrze (Poland); Boroń, Marta [Institute of Occupational Medicine and Environmental Health in Sosnowiec, ul. Kościelna 13, 41-200 Sosnowiec (Poland); Czuba, Zenon P. [Department of Microbiology and Immunology, School of Medicine with the Division of Dentistry, Medical University of Silesia, ul. Jordana 19, 41-808 Zabrze (Poland); Birkner, Ewa [Department of Biochemistry, School of Medicine with the Division of Dentistry, Medical University of Silesia, ul. Jordana 19, 41-808 Zabrze (Poland); Chwalba, Artur [SP ZOZ Municipal Hospital, Department of Internal Medicine, ul. Strzelców Bytomskich 11, 41-500 Chorzów (Poland); Hudziec, Edyta; Kasperczyk, Sławomir [Department of Biochemistry, School of Medicine with the Division of Dentistry, Medical University of Silesia, ul. Jordana 19, 41-808 Zabrze (Poland)

    2016-08-15

    The aim of the study was to investigate the influence of a short-term exposure to lead on the blood morphology and the levels of selected cytokines related to hematopoiesis in occupationally exposed workers. The study population included 37 males occupationally exposed to lead for 36 to 44 days. Their blood lead level raised from 10.7 ± 7.67 μg/dl at baseline to the level of 49.1 ± 14.1 μg/dl at the end of the study. The level of hemoglobin and values of MCH and MCHC were decreased due to a short-term exposure to lead by 2%, 2%, and 1%, respectively. The counts of WBC, LYM, and MXD increased significantly by 5%, 7%, and 35%. Similarly, the count of PLT increased by 7%, while PDW, MPV, and P-LCR decreased by 6%, 3%, and 9%, respectively. The levels of IL-7, G-CSF, HGF, PDGF AB/BB, SCF, and PECAM-1, decreased significantly by 30%, 33%, 8%, 30%, 25%, and 20%, respectively. A short-term occupational exposure to lead results in a decreased hemoglobin level and increased counts of WBC and PLT. Changes in counts and proportions of different types of leukocytes and decreased values of PLT indices, such as PDW, MPV, and P-LCR, due to the subacute lead-exposure may be associated with lead-induced decreased levels of cytokines related to hematopoiesis, including SCF, G-CSF, IL-7, and PDGF. - Highlights: • Subacute exposure to lead results in a decreased hemoglobin level. • Subacute exposure to lead results in increased counts of WBC and PLT. • Subacute exposure to lead decreases the levels of SCF, G-CSF, IL-7, and PDGF.

  20. Correlations between blood lead levels and some physiological and biochemical parameters of nutritional importance in some Nigerian women

    International Nuclear Information System (INIS)

    Ojo, J.O.; Oketayo, O.O.; Salawu, A.A.

    2011-01-01

    Lead is one of the common toxic materials widely occurring in the Nigerian environment. Even with the change to unleaded petrol, other significant sources still remain to be addressed. The deleterious impact of lead on human health, is well documented. The effects range from attention-grabbing mass mortality - as happened in Zamfara State recently, to no less serious but grossly neglected neurocognitive and neurodevelopmental effects, including lowered intelligence quotient scores. All these impacts are most serious in children, especially fetuses who receive their burden from their mothers. Ninety percent of lead in most adults resides in the bones with a half-life measured in decades. Therefore, fetuses and breast-fed children in this generation will remain seriously at risk of exposure to damaging lead levels no matter the efforts to rid our external environment of lead in the years to come. In this work, we have investigated the correlation between Blood Lead Levels (BLL) and up to 35 physiological and biochemical parameters of nutritional importance in 62 women of child-bearing age from lIe-lfe, Nigeria. BLL was determined in venous blood using Inductively- coupled plasma Mass Spectrometry. Our results show that BLL significantly correlates with Packed Cell Volume (PCV), Creatine Clearance, and the ratio of Low-density Lipids to High density Lipids in these women. When the subjects were stratified into different Nutritional Status group based on their Body Mass Index, significant correlation was found between BLL and Age but only in Obese subjects.

  1. The Shi'ites, the West and the Future of Democracy: Reframing Political Change in a Religio-secular World

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    John A Rees

    2006-02-01

    Full Text Available The present article critically reviews Paul McGeough’s important analysis of the most recent Iraq war within a broader consideration of secular-religious relations in international affairs. The thesis of Mission Impossible: The Sheikhs, the US and the Future of Iraq (2004 can be summarised around two ideas: that the US strategy in Iraq was flawed because it wilfully bypassed the traditional power structures of Iraqi society; and that these structures, formed around the tribe and the mosque, are anti-democratic thus rendering attempts at democratisation impossible. The article affirms McGeough’s argument concerning the inadequacy of the US strategy, but critically examines the author’s fatalism toward the democratic capacity of Iraqi structures, notably the structure of the mosque. By broadening the notion of democracy to include religious actors and agendas, and by an introductory interpretation of the Shi’ite community as vital players in an emerging Iraqi democracy, the article attempts to deconstruct the author’s secularist view that the world of the mosque exists in a ‘parallel universe’ to the liberal democratic West. Reframing the Shi’ites as essential actors in the democratic project thus situates political discourse in a ‘religio-secular world’ and brings the ‘other worlds’ of religion and secularism together in a sphere of interdependence. Such an approach emphasises the importance of post-secular structures in the discourses on democratic change.

  2. Determination of lead content in blood from the female transit police who belong to the Center and South units of Metropolitan Lima

    International Nuclear Information System (INIS)

    Arosquipa Aguilar, Graciela; Villegas Silva, Elvito

    2013-01-01

    The average content of lead in blood from the female police who belong to the center and south units from Metropolitan Lima in 2005 and 2008 have been below the threshold level (20 μg Pb/dL) for both workers in the street and in offices. Nevertheless, there is the possibility of occupational risk for the toxicity of lead in any concentration in a human being. For p < 0,05 there are no significant differences between the average contents of lead in blood for the workers in the streets but in different units; and there was similar situation for the workers in offices, in both years 2005 and 2008. (author)

  3. Influence of “Chelavite” Mineral Supplement Use on Cadmium and Lead Content in Blood, Wool and Milk of Heavy Cows

    Directory of Open Access Journals (Sweden)

    Anna Borisovna ANDREEVA

    2015-07-01

    Full Text Available The purpose of this research was to study the influence of this supplement use on the concentration of cadmium and lead in blood serum, wool and milk of heavy cows. The cows of milking herd of black-and-white breed, of 3-5 years old were the object of research. Their yearly milk production was 6 thousand litters (control and experimental group, each having 15 heads. The cows have been fed according to the balanced ration for heavy cows. The mineral supplement dose was determined according to the instruction for application for cows of experimental group with feed. The curative dose was 0.6 ml for 10 kg of body mass 1 time a day during 30 days. The samples were taken before giving the mineral supplement “Chelavite” and after the course had finished. The device Unicam AAS-939 was used to determine the cadmium and lead content in blood, wool and milk by way of atomic absorption spectrophotometry. It has been found that the cadmium level reduced by 2.35 times, the lead level reduced by 1,5 times in cows blood, the cadmium level reduced by 1.33 times, the lead level reduced by 4.34 times in cows wool, the cadmium level reduced by 2.2 times, the lead level reduced by 3.7 times in cows milk after giving them mineral supplement “Chelavite”. Thus, the application of chelate compounds in form of “Chelavite” for cows reduces concentration of heavy metals such as cadmium and lead. Then this is one of the ways to improve the milk quality.

  4. Cadmium, lead and mercury concentrations and their influence on morphological parameters in blood donors from different age groups from southern Poland.

    Science.gov (United States)

    Janicka, Monika; Binkowski, Łukasz J; Błaszczyk, Martyna; Paluch, Joanna; Wojtaś, Włodzimierz; Massanyi, Peter; Stawarz, Robert

    2015-01-01

    Due to industrial development, environmental contamination with metals increases which leads to higher human exposure via air, water and food. In order to evaluate the level of the present exposition, the concentrations of metals can be measured in such biological materials as human blood. In this study, we assessed the concentrations of cadmium (Cd), mercury (Hg) and lead (Pb) in blood samples from male blood donors from southern Poland (Europe) born in 1994 (n=30) and between 1947 and 1955 (n=30). Higher levels of Pb were seen in the group of older men (4.48 vs 2.48μg/L), whereas the Hg levels were lower (1.78 vs 4.28μg/L). Cd concentrations did not differ between age groups (0.56μg/L). The levels of Cd and Pb in older donors were significantly correlated (Spearman R 0.5135). We also observed a positive correlation between the number of red blood cells (RBC) and Hg concentrations in the older group (Spearman R 0.4271). Additionally, we noted numerous correlations among morphological parameters. Based on our results, we can state that metals influence the blood morphology and their concentrations in blood vary among age groups. Copyright © 2014 Elsevier GmbH. All rights reserved.

  5. Secular trends in hip fractures worldwide: opposing trends East versus West.

    Science.gov (United States)

    Ballane, Ghada; Cauley, Jane A; Luckey, Marjorie M; Fuleihan, Ghada El-Hajj

    2014-08-01

    Despite wide variations in hip rates fractures worldwide, reasons for such differences are not clear. Furthermore, secular trends in the age-specific hip fracture rates are changing the world map of this devastating disease, with the highest rise projected to occur in developing countries. The aim of our investigation is to systematically characterize secular trends in hip fractures worldwide, examine new data for various ethnic groups in the United States, evidence for divergent temporal patterns, and investigate potential contributing factors for the observed change in their epidemiology. All studies retrieved through a complex Medline Ovid search between 1966 and 2013 were examined. For each selected study, we calculated the percent annual change in age-standardized hip fracture rates de-novo. Although occurring at different time points, trend breaks in hip fracture incidence occurred in most Western countries and Oceania. After a steep rise in age-adjusted rates in these regions, a decrease became evident sometimes between the mid-seventies and nineties, depending on the country. Conversely, the data is scarce in Asia and South America, with evidence for a continuous rise in hip fracture rates, with the exception of Hong-Kong and Taiwan that seem to follow Western trends. The etiologies of these secular patterns in both the developed and the developing countries have not been fully elucidated, but the impact of urbanization is at least one plausible explanation. Data presented here show close parallels between rising rates of urbanization and hip fractures across disparate geographic locations and cultures. Once the proportion of the urban population stabilized, hip fracture rates also stabilize or begin to decrease perhaps due to the influence of other factors such as birth cohort effects, changes in bone mineral density and BMI, osteoporosis medication use and/or lifestyle interventions such as smoking cessation, improvement in nutritional status and fall

  6. Effect of testosterone administration on lead induced zincprotoporphyrin in blood concentration in castrated male rabbits

    Energy Technology Data Exchange (ETDEWEB)

    Wibowo, A.A.E.; Zielhuis, R.L.

    1981-11-01

    The influence of testosterone propionate on the concentration of zincprotoporphyrin in blood (ZPP) of castrated lead treated rabbits was investigated. The experimental design allowed comparison of the relative ZPP increase (RZI) in testosterone treated and non testosterone treated rabbits. Testosterone was administered by subcutaneous injection of 3 mg/kg body weight/day for 7 consecutive days directly prior to the lead exposure, which was performed by subcutaneous injection of 0.50 mg lead acetate/kg body weight, three times a week for 7 weeks. No effect was found on the hemoglobin concentration (Hb) and hematocrit (Ht) and on the increase of body weight during the experiment. But the increase of RZI in the non testosterone treated rabbits was significantly steeper and earlier than in the testosterone treated group. The possible consequences of the findings had been further commented on.

  7. Protective Effects of Vitamin C (Ascorbic Acid in Lead Acetate Exposed Diabetic Male Rats: Evaluation of Blood Biochemical Parameters and Testicular Histopathology

    Directory of Open Access Journals (Sweden)

    Alireza AYOUBI

    2015-01-01

    Full Text Available The aim of this study was to investigate the protective effects of vitamin C against lead toxicity by measuring the blood parameters and studying histopathology of testis in diabetic male rats. Wister rats (42 were randomly assigned into7 groups: I healthy; II fed lead acetate only; III vitamin C administered only; IV diabetic; V diabetic rats administered by vitamin C; VI diabetic rats given lead acetate and VII diabetic rats received lead acetate and vitamin C. The diabetic and lead groups had higher glucose, cholesterol, LDL, triglycerides and lower insulin and HDL concentration than the control group. It was found that vitamin C administration led to a lower level of blood glucose, cholesterol, LDL and triglycerides and higher HDL concentration in diabetic rats significantly. It was concluded that the antioxidant property of vitamin C resulted in reducing the oxidative stress complications of toxic levels of lead acetate in diabetic rats.

  8. Lead Poison Detection

    Science.gov (United States)

    1976-01-01

    With NASA contracts, Whittaker Corporations Space Science division has developed an electro-optical instrument to mass screen for lead poisoning. Device is portable and detects protoporphyrin in whole blood. Free corpuscular porphyrins occur as an early effect of lead ingestion. Also detects lead in urine used to confirm blood tests. Test is inexpensive and can be applied by relatively unskilled personnel. Similar Whittaker fluorometry device called "drug screen" can measure morphine and quinine in urine much faster and cheaper than other methods.

  9. Long-Term Seafloor Electromagnetic Observation in the Northwest Pacific May Detect the Vector Geomagnetic Secular Variation

    Directory of Open Access Journals (Sweden)

    H Toh

    2010-03-01

    Full Text Available Sea Floor ElectroMagnetic Stations (SFEMSs are now operating at two deep seafloor sites called the 'WPB' and the 'NWP' in the West Philippine Basin and the Northwest Pacific Basin, respectively. One of the main objectives of the SFEMSs is to detect the geomagnetic secular variations on the deep seafloor where long-term geomagnetic observations have not so far been achieved. SFEMSs can measure the absolute geomagnetic total force as well as the geomagnetic vector field with precise attitude monitoring systems. The vector geomagnetic time-series that was observed for more than 5 years revealed that the westward drift of the equatorial dipole dominates in the geomagnetic secular variation at the NWP.

  10. Religious and territorial identities in a cosmopolitan and secular city: youth in Amsterdam

    NARCIS (Netherlands)

    Mamadouh, V.; van der Welle, I.; Brunn, S.D.

    2015-01-01

    Religion is a much contested issue in Dutch politics and more specifically in Amsterdam. We investigate whether and how religion works as an obstacle or a vehicle for integration for youth in the secular and cosmopolitan Amsterdam. First, we describe the role religion played in the process of nation

  11. Associations of blood lead, cadmium, and mercury with estimated glomerular filtration rate in the Korean general population: Analysis of 2008–2010 Korean National Health and Nutrition Examination Survey data

    International Nuclear Information System (INIS)

    Kim, Yangho; Lee, Byung-Kook

    2012-01-01

    Introduction: The objective of this study was to evaluate associations between blood lead, cadmium, and mercury levels with estimated glomerular filtration rate in a general population of South Korean adults. Methods: This was a cross-sectional study based on data obtained in the Korean National Health and Nutrition Examination Survey (KNHANES) (2008–2010). The final analytical sample consisted of 5924 participants. Estimated glomerular filtration rate (eGFR) was calculated using the MDRD Study equation as an indicator of glomerular function. Results: In multiple linear regression analysis of log2-transformed blood lead as a continuous variable on eGFR, after adjusting for covariates including cadmium and mercury, the difference in eGFR levels associated with doubling of blood lead were −2.624 mL/min per 1.73 m² (95% CI: −3.803 to −1.445). In multiple linear regression analysis using quartiles of blood lead as the independent variable, the difference in eGFR levels comparing participants in the highest versus the lowest quartiles of blood lead was −3.835 mL/min per 1.73 m² (95% CI: −5.730 to −1.939). In a multiple linear regression analysis using blood cadmium and mercury, as continuous or categorical variables, as independent variables, neither metal was a significant predictor of eGFR. Odds ratios (ORs) and 95% CI values for reduced eGFR calculated for log2-transformed blood metals and quartiles of the three metals showed similar trends after adjustment for covariates. Discussion: In this large, representative sample of South Korean adults, elevated blood lead level was consistently associated with lower eGFR levels and with the prevalence of reduced eGFR even in blood lead levels below 10 μg/dL. In conclusion, elevated blood lead level was associated with lower eGFR in a Korean general population, supporting the role of lead as a risk factor for chronic kidney disease.

  12. Secular Trends in Meal and Snack Patterns among Adolescents from 1999 to 2010.

    Science.gov (United States)

    Larson, Nicole; Story, Mary; Eisenberg, Marla E; Neumark-Sztainer, Dianne

    2016-02-01

    Linkages between snack patterns, diet, and obesity in adolescents likely depend on the consumption of main meals, how often snacks are prepared away from home, and whether energy-dense, nutrient-poor snack foods and sugary drinks are frequently consumed. Nutrition-based interventions need to be informed by an understanding of how secular changes in the contribution of snacks to dietary intake may be related to changes in meal frequency as well as how these trends differ by sociodemographic characteristics. To examine secular trends from 1999 to 2010 in meal and snack patterns among adolescents. A repeated cross-sectional design was used. Participants from Minneapolis/St Paul, MN, secondary schools completed classroom-administered surveys and food frequency questionnaires in 1999 (n=2,598) and 2010 (n=2,540). Weekly meal frequencies; number of snacks consumed on school and vacation/weekend days; frequent consumption of snacks prepared away from home (≥3 times/week); and daily servings of energy-dense, nutrient-poor food/drinks that are commonly consumed at snack occasions. Trends from 1999 to 2010 were examined using inverse probability weighting to control for differences in sociodemographic characteristics in the two samples. Mean frequencies of breakfast and lunch increased modestly in the overall population (both P values snacks consumed on schools days (Psnacks prepared away from home, there was a secular decrease in energy-dense, nutrient-poor food/drink consumption (Psnack trends among adolescents suggests the need for targeted efforts to ensure public health messages reach low-income and ethnic/racial minority population subgroups most vulnerable to poor nutrition and the development of obesity. Copyright © 2016 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  13. Low blood lead levels impair intellectual and hematological function in children from Cartagena, Caribbean coast of Colombia.

    Science.gov (United States)

    Alvarez-Ortega, Neda; Caballero-Gallardo, Karina; Olivero-Verbel, Jesus

    2017-12-01

    Lead produces numerous biochemical and physiological changes in humans, including hematological disorders, toxic effects on the central nervous system and in the function of several organs. The aim of this study was to determine blood lead levels (BLL) in children from Cartagena, Colombia, associating those with hematological and liver damage markers, the intelligence quotient (IQ), as well as with gene expression of the aminolevulinate dehydratase (ALAD), superoxide dismutase 1 (SOD1), gamma interferon (INF-γ), tumor necrosis factor (TNF) and tumor protein (p53). To achieve this purpose, 118 blood samples were collected from children 5-16 years old, with their respective informed consent from their parents. BLL was measured by atomic absorption; hematological parameters were obtained with automated systems; plasma was utilized to analyze hepatic toxicity markers, alanine aminotransferase (ALT), gamma-glutamyltransferase (γ-GT) and alkaline phosphatase (ALP); the Kaufman Brief Intelligence Test (K-BIT) was administered to measure the IQ; and gene expression was quantified from blood RNA. The mean BLL was 1.7±0.3μg/dL. A low proportion of the children (3.4%) had BLL above the CDC recommended limit (5μg/dL). BLL were correlated weakly, but negatively with child age, weight, height, body mass index, platelets wide distribution, mean platelet volume, γ-GT and IQ. There were not significant changes in the expression of evaluated genes. These results support the hypothesis that BLL below 5μg/dL may still be a detrimental factor on children's cognitive abilities, development and hematology, in line with recent concerns that there is no safe level of pediatric lead exposure. Copyright © 2017 Elsevier GmbH. All rights reserved.

  14. Association of Lead Levels and Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Neha Bansal MD

    2017-03-01

    Full Text Available Background: Cerebral palsy is a common motor disability in childhood. Raised lead levels affect cognition. Children with cerebral palsy may have raised lead levels, further impairing their residual cognitive motor and behavioral abilities. Environmental exposure and abnormal eating habits may lead to increased lead levels. Aims and Objectives: To measure blood lead levels in children with cerebral palsy and compare them with healthy neurologically normal children. To correlate blood lead levels with environmental factors. Material and Methods: Design: Prospective case-control study. Setting: Tertiary care hospital. Participants: Cases comprised 34 children with cerebral palsy, and controls comprised 34 neurologically normal, age- and sex-matched children. Methods: Clinical and demographic details were recorded as per proforma. Detailed environmental history was recorded to know the source of exposure to lead. These children were investigated and treated as per protocol. Venous blood was collected in ethylenediaminetetraacetic acid vials for analysis of blood lead levels. Lead levels were estimated by Schimadzu Flame AA-6800 (atomic absorption spectrophotometer. Data were analyzed using SPSS version 17. P < .05 was taken as significant. Results: Mean blood lead levels were 9.20 ± 8.31 µg/dL in cerebral palsy cases and 2.89 ± 3.04 µg/dL in their controls (P < .001. Among children with cerebral palsy, 19 (55.88% children had blood lead levels ≥5 µg/dL. Lead levels in children with pica were 12.33 ± 10.02 µg/dL in comparison to children with no history of pica, 6.70 ± 4.60 µg/dL (P = .029. No correlation was found between hemoglobin and blood lead levels in cases and controls. Conclusion: In our study, blood lead levels are raised in children with cerebral palsy. However, further studies are required to show effects of raised levels in these children.

  15. Association of Childhood Blood Lead Levels With Cognitive Function and Socioeconomic Status at Age 38 Years and With IQ Change and Socioeconomic Mobility Between Childhood and Adulthood.

    Science.gov (United States)

    Reuben, Aaron; Caspi, Avshalom; Belsky, Daniel W; Broadbent, Jonathan; Harrington, Honalee; Sugden, Karen; Houts, Renate M; Ramrakha, Sandhya; Poulton, Richie; Moffitt, Terrie E

    2017-03-28

    Many children in the United States and around the world are exposed to lead, a developmental neurotoxin. The long-term cognitive and socioeconomic consequences of lead exposure are uncertain. To test the hypothesis that childhood lead exposure is associated with cognitive function and socioeconomic status in adulthood and with changes in IQ and socioeconomic mobility between childhood and midlife. A prospective cohort study based on a population-representative 1972-1973 birth cohort from New Zealand; the Dunedin Multidisciplinary Health and Development Study observed participants to age 38 years (until December 2012). Childhood lead exposure ascertained as blood lead levels measured at age 11 years. High blood lead levels were observed among children from all socioeconomic status levels in this cohort. The IQ (primary outcome) and indexes of Verbal Comprehension, Perceptual Reasoning, Working Memory, and Processing Speed (secondary outcomes) were assessed at age 38 years using the Wechsler Adult Intelligence Scale-IV (WAIS-IV; IQ range, 40-160). Socioeconomic status (primary outcome) was assessed at age 38 years using the New Zealand Socioeconomic Index-2006 (NZSEI-06; range, 10 [lowest]-90 [highest]). Of 1037 original participants, 1007 were alive at age 38 years, of whom 565 (56%) had been lead tested at age 11 years (54% male; 93% white). Mean (SD) blood lead level at age 11 years was 10.99 (4.63) µg/dL. Among blood-tested participants included at age 38 years, mean WAIS-IV score was 101.16 (14.82) and mean NZSEI-06 score was 49.75 (17.12). After adjusting for maternal IQ, childhood IQ, and childhood socioeconomic status, each 5-µg/dL higher level of blood lead in childhood was associated with a 1.61-point lower score (95% CI, -2.48 to -0.74) in adult IQ, a 2.07-point lower score (95% CI, -3.14 to -1.01) in perceptual reasoning, and a 1.26-point lower score (95% CI, -2.38 to -0.14) in working memory. Associations of childhood blood lead level with deficits in

  16. Evaluation of Lead, Cadmium, Zinc and Copper Levels in Blood, Hair and Teeth of Children

    International Nuclear Information System (INIS)

    Abdel -Latif, A.; EL- Bedewi, A.F.; Gad, A.; Mortada, A.A.

    2004-01-01

    There is a general agreement that children are a population that suffered increased risk of lead (Pb) and cadmium (Cd) exposure with adverse health effects. The aim of this study is to evaluate the environmental exposure to Pb and Cd in children living in Cairo since birth and their effects on other essential elements such as zinc (Zn) and copper (Cu). The relationships between these indicators for exposure and children characteristics such as sex, weight, height, blood pressure and smoking habits of parents were also estimated. Forty children (23 males and 17 females) aged 5-7 years had been included in this study. Levels of elements in the samples were determined using atomic absorption spectroscopy. The levels of Pb in blood (Pb-B), hair (Pb-H) and teeth (Pb-T) were 18.17 ± 5.35 fig/dl, 6.29 ± 2.07 fig/g and 8.07± 1.98 fig/g, respectively. Significant differences were observed between boys and girls as regards Pb-H (P<0.001)and Pb-T(P<0.05). The Cd levels were 0.603 ±0.08 μg/dl in blood (Cd-B), 0.933 ± 0.18 fig/g in hair (Cd-H) and 4.825± 0.57 μg/g in teeth (Cd-T). Boys showed higher significant increases in Cd-B than girls (P < 0.001). Concerning Zn, the levels were 57.43± 6.86 μg/dl,148.18± 11.76μg/g and 100.32± 20.28 μg/dl in blood (Zn-B), hair (Zn-H) and teeth(Zn-T),correspondingly Girls displayed significant higher levels of Zn-H than boys (P < 0.05). Regarding Cu in blood (Cu-B), in hair (Cu-H) and in teeth (Cu-T), they were 113.42± 9.89 μg/dl, 17.9±4.18 μg/g and 10.6± 3.04 μg/g, respectively. Girls showed significant higher levels of Cu-H than boys (P < 0.05). The passive smoking children exhibited significant increased levels of Pb, Cd and Cu in blood, hair and teeth when compared to the non-exposed children. On the other hand, passive smoking leads to decrease in Zn concentrations in the three studied samples. The proper mechanism of Zn affection was explained by interactions with Cd, Pb and Cu. Correlation between Pb and Cd with

  17. Examination of US puberty-timing data from 1940 to 1994 for secular trends

    DEFF Research Database (Denmark)

    Euling, Susan Y; Herman-Giddens, Marcia E; Lee, Peter A

    2008-01-01

    different methods. As a result, conclusions from data comparisons have not been consistent. An expert panel was asked to evaluate the weight of evidence for whether the data, collected from 1940 to 1994, are sufficient to suggest or establish a secular trend in the timing of puberty markers in US boys...

  18. Secular variation of cosmic ray intensity recorded in the radiocarbon concentration of tree rings

    International Nuclear Information System (INIS)

    Kigoshi, K.

    1978-01-01

    Study of the secular variations of cosmic ray intensity on the basis of the secular variations of atmospheric radiocarbon concentration in 8000 years is considered. The data on the radiocarbon concentration is received by three laboratories using the dendrochronologically dated tree ring samples. In order to use the data the variations due to geochemical process must be eliminated. From this point of view the climatic effect on the atmospheric radiocarbon concenttration is estimated using the data on sunspot number and global surface temperature during 1650-1800 y. The barge influence of climate on the atmospheric radiocarbon concentration syggests the small contribution of change of radiocarbon production rate to the short-period fluctuations in the atmospheric radiocarbon concentration. Elimination of variations caused by climate and sunspot activities from the variations in atmospheric radiocarbon concentration gives a long-term scale of its concentration which agrees well to the observed paleo-geomagnetic data

  19. Blood lead concentrations in wild birds from a polluted mining region at Villa de La Paz, San Luis Potosi, Mexico.

    Science.gov (United States)

    Chapa-Vargas, Leonardo; Mejia-Saavedra, Jose J; Monzalvo-Santos, Karina; Puebla-Olivares, Fernando

    2010-01-01

    This investigation was undertaken to determine the concentrations of lead in bird blood samples from a mining region in central Mexico and to compare concentrations among several different feeding guilds. The study took place in the Mexican state of San Luis Potosi in a region known as "Villa de la Paz." This is one of the most intensely exploited mining regions in central Mexico and has been actively mined for over four centuries. Lead concentrations from bird blood samples taken from four polluted sites were significantly higher than those from a control, unpolluted site (F = 6.3, P birds from a highly polluted site were higher than those from a site that has intermediate pollution levels (P birds had significantly lower lead concentrations compared to granivores, frugivores-insectivores, and omnivores (F = 4.86, P = 0.004), and a large proportion of all individuals had blood lead concentrations indicative of low, sub-lethal toxic effects. Finally, in two polluted sites, remarkably small numbers of insectivore-frugivores, and granivores were trapped, and in one polluted site a large number of insectivores was trapped (X(2) = 29.9, P = 0.03), and no differences in proportions of migrants and non-migrants were found among sampling sites (X(2) = 0.6, P = 0.96). To date, it has not been determined to what extent constant exposure to these levels of pollution can influence health at the individual level, lifespan, and, therefore, population demography of birds from this region.

  20. A good social work: women's clubs, libraries, and the construction of a secular society in Utah, 1890-1920.

    Science.gov (United States)

    Stauffer, Suzanne M

    2011-01-01

    After the renunciation of polygamy, Mormon women formed secular women's clubs as a means of collaborating with non-Mormon women in the construction of a shared secular society. Their common goal was the establishment and maintenance of the mainstream American social order. Activity in these clubs extended women's sphere into the public realm through socially acceptable public activities such as the temperance cause, civic improvements, political reform movements, and child welfare. The women campaigned for public support of libraries as institutions that would construct, preserve, and transmit American culture, educate the young, strengthen the home and family, and reform society.

  1. Secular trends of body sizes in Korean children and adolescents: from 1965 to 2010

    Directory of Open Access Journals (Sweden)

    Jin Soo Moon

    2011-11-01

    Full Text Available An anthropometric survey is one of the most important approaches to use when evaluating the health status of children. Secular trends in body sizes, such as height, weight, head circumference, chest circumference, and body mass index showed significant changes over 40 years in Korea. A series of periodic surveys were conducted in 1967, 1975, 1985, 1997, and 2005 by the Korean Pediatric Society and Ministry of Health and Welfare. The quality of data from school health examinations and the Korea National Health and Nutrition Examination Survey has improved, so we can use them now as resources for anthropometric analysis. The final height differences between 1965 and 1997 were 4.5 cm both in boys (168.9 cm in 1965; 173.4 cm in 1997 and girls (155.9 cm in 1965; 160.4 cm in 1997. The differences between 1997 and 2005 were 0.9 cm in boys (174.3cm in 2005 and 0.8 cm in girls (161.2 cm in 2005. There was no difference in final height measurements between 2005 and 2010. An increase in body size at earlier teen ages was pronounced during these decades compared to the previous generation; however, little change has been identified more recently. Body size has been increasing, and obesity has become more prevalent. Systems that gather data should be updated in order to cope with these secular trends. In an upcoming era of secular trends that would be in a slow transition, several surveys that include body measurements should be prepared to meet future needs.

  2. Observations of secular changes in the kinematic model of SS433

    International Nuclear Information System (INIS)

    Collins, G.W. II; Newsom, G.H.

    1982-01-01

    In this paper the authors present evidence that several of the defining parameters of the Kinematic Model for SS433 are not constant but rather exhibit long term systematic changes. Recent data confirm the existence of the previously reported decrease in the precessional period. The value for this period change, when combined with the observed change in the period of the synodic spectral variations, implies that the orbital period is not significantly changing on a time scale less than 1000 years. In addition they find mounting evidence for a statistically significant (4sigma) secular change in the cone angle theta at a rate of about -1.5 x 10 -3 deg/day. However, the surprisingly short time scales implied by the observed values of dP/dt and dtheta/dt when combined with estimates of the system age suggest the possible existence of detectable higher time derivatives. This view is supported by the most recent data which suggest a value for d 2 P/dt 2 approximately 10 -5 (days) -1 . It is possible to understand these secular changes in terms of the motions to be expected from an object exhibiting classical precession in response to an external torque. (Auth.)

  3. Geographical localisation of the geomagnetic secular variation

    DEFF Research Database (Denmark)

    Aubert, Julien; Finlay, Chris; Olsen, Nils

    2013-01-01

    the model and geomagnetic data previously processed in the same way. Our results suggest that conservation of angular momentum and heterogeneous thermochemical boundary control in the coupled inner core / outer core / mantle system are central to understanding how Earth’s magnetic field currently evolves......., westward moving, magnetic flux patches at the core surface. Despite its successes in explaining the main morphological properties of Earth’s magnetic field, self-consistent numerical modelling of the geodynamo has so far failed to reproduce this field variation pattern. Furthermore its magnetohydrodynamic...... control from either, or both, the inner-core boundary and the core-mantle boundary. In addition to presenting an Earth-like magnetic field morphology, these new numerical models also reproduce the morphology and localization of geomagnetic secular variation. In our models, the conservation of the angular...

  4. [Adolphe Quetelet and biopolitics as secularized theology].

    Science.gov (United States)

    Pich, Santiago

    2013-01-01

    The article recaptures the work of an author who has been forgotten by the contemporary social sciences, that is, the Belgium polymath Adolphe Quetelet. Focusing on his main work, Sur l'homme et le développement de ses facultés, ou Essai de physique sociale, the study underscores how the secularization of theological principles within the realm of science was important to the construction of Quetelet's work. His dual engagement in science and politics is pertinent here, as he was the main nineteenth-century force behind the incorporation of statistics as a science essential to the State's ability to govern its people. He also played a relevant role in the realization of the hegemonic political project of modernity, biopolitics, and its influence in the field of biomedicine in the nineteenth and twentieth centuries.

  5. Religious and secular volunteering: A comparison between immigrants and non-immigrants in the Netherlands.

    NARCIS (Netherlands)

    Carabain, C.L.; Bekkers, R.H.F.P.

    2011-01-01

    Using new survey data from the Netherlands, we find that non-immigrants are more likely to volunteer for secular organisations than guest worker immigrants and postcolonial citizen immigrants. In contrast, non-immigrants are less likely to engage in religious volunteering than both immigrant groups.

  6. Manganese and lead in children's blood and airborne particulate matter in Durban, South Africa.

    Science.gov (United States)

    Batterman, Stuart; Su, Feng-Chiao; Jia, Chunrong; Naidoo, Rajen N; Robins, Thomas; Naik, Inakshi

    2011-02-15

    Despite the toxicity and widespread use of manganese (Mn) and lead (Pb) as additives to motor fuels and for other purposes, information regarding human exposure in Africa is very limited. This study investigates the environmental exposures of Mn and Pb in Durban, South Africa, a region that has utilized both metals in gasoline. Airborne metals were sampled as PM(2.5) and PM(10) at three sites, and blood samples were obtained from a population-based sample of 408 school children attending seven schools. In PM(2.5), Mn and Pb concentrations averaged 17±27 ng m(-3) and 77±91 ng m(-3), respectively; Mn concentrations in PM(10) were higher (49±44 ng m(-3)). In blood, Mn concentrations averaged 10.1±3.4 μg L(-1) and 8% of children exceeded 15 μg L(-1), the normal range. Mn concentrations fit a lognormal distribution. Heavier and Indian children had elevated levels. Pb in blood averaged 5.3±2.1 μg dL(-1), and 3.4% of children exceeded 10 μg dL(-1), the guideline level. Pb levels were best fit by a mixed (extreme value) distribution, and boys and children living in industrialized areas of Durban had elevated levels. Although airborne Mn and Pb concentrations were correlated, blood levels were not. A trend analysis shows dramatic decreases of Pb levels in air and children's blood in South Africa, although a sizable fraction of children still exceeds guideline levels. The study's findings suggest that while vehicle exhaust may contribute to exposures of both metals, other sources currently dominate Pb exposures. Copyright © 2010 Elsevier B.V. All rights reserved.

  7. Secular dynamics of hierarchical multiple systems composed of nested binaries, with an arbitrary number of bodies and arbitrary hierarchical structure - II. External perturbations: flybys and supernovae

    Science.gov (United States)

    Hamers, Adrian S.

    2018-05-01

    We extend the formalism of a previous paper to include the effects of flybys and instantaneous perturbations such as supernovae on the long-term secular evolution of hierarchical multiple systems with an arbitrary number of bodies and hierarchy, provided that the system is composed of nested binary orbits. To model secular encounters, we expand the Hamiltonian in terms of the ratio of the separation of the perturber with respect to the barycentre of the multiple system, to the separation of the widest orbit. Subsequently, we integrate over the perturber orbit numerically or analytically. We verify our method for secular encounters and illustrate it with an example. Furthermore, we describe a method to compute instantaneous orbital changes to multiple systems, such as asymmetric supernovae and impulsive encounters. The secular code, with implementation of the extensions described in this paper, is publicly available within AMUSE, and we provide a number of simple example scripts to illustrate its usage for secular and impulsive encounters and asymmetric supernovae. The extensions presented in this paper are a next step towards efficiently modelling the evolution of complex multiple systems embedded in star clusters.

  8. Traditional vs. secular values and work-life well being across Europe

    OpenAIRE

    Georgellis, Y; Lange, T

    2007-01-01

    This paper examines how culture, defined in our analysis by reference to traditional versus secular values, affects the work-life balance across Europe. Specifically, we focus on the factors that affect the propensity of individuals across 30 European countries to exhibit behavioural patterns in the work and life domains consistent with the segmentation, spillover or compensation hypotheses. Testing the latter assertions, our empirical analysis replicates the study by Judge and Watanabe (1994...

  9. GFR and Blood Lead Levels in Gas Station Workers Based on δ-Alad Gene Polymorphisms

    Directory of Open Access Journals (Sweden)

    Lantip Rujito

    2015-04-01

    showed that the proportion of ALAD genotype for ALAD 1-1, 1-2 and 2-2 were 94.7%, 5.3%, and 0% respectively. The mean of serum levels in homozygous 1-1 was 15.94 ppb and heterozygote 1-2 was 1.15 ppb. GFR of participants ranged from 71.11 mL/min to 185.20 mL/min with a mean of 117.34mL/min. There was no correlation between serum Pb and GFR (p = 0.19. Study also could not determine the correlation between GFR and ALAD gene Polymorphism. Discussion: Study then concluded that there was no correlation between blood lead levels in the GFR on each δ-ALAD genotypes. Keywords: Lead intoxication, GFR, δ-ALAD, gas station workers

  10. Increased levels of lead in the blood and frequencies of lymphocytic micronucleated binucleated cells among workers from an electronic-waste recycling site.

    Science.gov (United States)

    Wang, Qian; He, An M; Gao, Bo; Chen, Lan; Yu, Qiang Z; Guo, Huan; Shi, Bin J; Jiang, Pu; Zhang, Zeng Y; Li, Ping L; Sheng, Ying G; Fu, Mo J; Wu, Chun T; Chen, Min X; Yuan, Jing

    2011-01-01

    In recent years, adverse health effects of chemicals from electronic waste (e-waste) have been reported. However, little is known about the genotoxic effects of chemicals in e-waste. In the present study, air concentrations of the toxic metals at e-waste and control sites were analyzed using inductively-coupled plasma mass spectrometry. Levels of toxic metals (lead, copper and cadmium) in blood and urine were detected using atomic absorption spectrophotometry in 48 exposed individuals and 56 age- and sex-matched controls. The frequencies of lymphocytic micronucleated binucleated cells (MNBNCs) were determined using a cytokinesis-block micronucleus assay. Results indicated that blood lead levels were significantly higher in the exposed group (median: 11.449 μg/dL, 1st/3rd quartiles: 9.351-14.410 μg/dL) than in the control group (median: 9.104 μg/dL, 1st/3rd quartiles: 7.275-11.389 μg/dL). The exposed group had higher MNBNCs frequencies (median: 4.0 per thousand, 1st/3rd quartiles: 2.0-7.0 per thousand) compared with the controls (median: 1.0 per thousand, 1st/3rd quartiles: 0.0-2.0 per thousand). Additionally, MNBNCs frequencies and blood lead levels were positively correlated (r = 0.254, phistory of working with e-waste was a predictor for increased blood lead levels and MNBNCs frequencies in the subjects. The results suggest that both the living and occupational environments at the e-waste site may be risk factors for increased MNBNCs frequencies among those who are exposed.

  11. American medicine as religious practice: care of the sick as a sacred obligation and the unholy descent into secularization.

    Science.gov (United States)

    Wardlaw, Margaret P

    2011-03-01

    Modern medicine serves a religious function for modern Americans as a conduit through which science can be applied directly to the human body. The first half of this paper will focus on the theoretical foundations for viewing medicine as a religious practice arguing that just as a hierarchical structured authoritarian church historically mediated access to God, contemporary Western medicine provides a conduit by which the universalizable truths of science can be applied to the human being thereby functioning as a new established religion. I will then illustrate the many parallels between medicine and religion through an analysis of rituals and symbols surrounding and embedded within the modern practice of medicine. This analysis will pay special attention to the primacy placed on secret interior knowledge of the human body. I will end by responding to the hope for a "secularization of American medicine," exploring some of the negative consequences of secularization, and arguing that, rather than seeking to secularize, American medicine should strive to use its religious features to offer hope and healing to the sick, in keeping with its historically religious legacy.

  12. The identification of lead ammunition as a source of lead exposure in First Nations: The use of lead isotope ratios

    International Nuclear Information System (INIS)

    Tsuji, Leonard J.S.; Wainman, Bruce C.; Martin, Ian D.; Sutherland, Celine; Weber, Jean-Philippe; Dumas, Pierre; Nieboer, Evert

    2008-01-01

    The use of lead shotshell to hunt water birds has been associated with lead-contamination in game meat. However, evidence illustrating that lead shotshell is a source of lead exposure in subsistence hunting groups cannot be deemed definitive. This study seeks to determine whether lead shotshell constitutes a source of lead exposure using lead isotope ratios. We examined stable lead isotope ratios for lichens, lead shotshell and bullets, and blood from residents of Fort Albany and Kashechewan First Nations, and the City of Hamilton, Ontario, Canada. Data were analyzed using ANOVA and regression analyses. ANOVA of isotope ratios for blood revealed significant differences with respect to location, but not sex. Hamilton differed from both Kashechewan and Fort Albany; however, the First Nations did not differ from each other. ANOVA of the isotope ratios for lead ammunition and lichens revealed no significant differences between lichen groups (north and south) and for the lead ammunition sources (pellets and bullets). A plot of 206 Pb/ 204 Pb and 206 Pb/ 207 Pb values illustrated that lichens and lead ammunition were distinct groupings and only the 95% confidence ellipse of the First Nations group overlapped that of lead ammunition. In addition, partial correlations between blood-lead levels (adjusted for age) and isotope ratios revealed significant (p 206 Pb/ 204 Pb and 206 Pb/ 207 Pb, and a significant negative correlation for 208 Pb/ 206 Pb, as predicted if leaded ammunition were the source of lead exposure. In conclusion, lead ammunition was identified as a source of lead exposure for First Nations people; however, the isotope ratios for lead shotshell pellets and bullets were indistinguishable. Thus, lead-contaminated meat from game harvested with lead bullets may also be contributing to the lead body burden

  13. Lead poisoning following ingestion of pieces of lead roofing plates: pica-like behavior in an adult.

    Science.gov (United States)

    Sabouraud, Sabine; Testud, François; Descotes, Jacques; Benevent, Monique; Soglu, Gilbert

    2008-03-01

    A 37-year-old man was admitted to hospital after complaining of abdominal pain for the past two weeks. On admission the abdominal radiograph showed multiple radio-opaque flecks dispersed throughout the gastrointestinal tract. Blood testing showed hemoglobin level 8.7 g/dL and a blood lead level of 112.4 microg/dL. The family interview revealed that the patient had pica-like behavior since childhood. He was a site foreman and had been ingesting pieces of roofing plates for a few weeks. The patient was treated with laxatives and CaNa(2)EDTA therapy was initiated. The blood lead level then dropped to 69.9 microg/dL. The patient received two subsequent courses of oral succimer and the blood lead level decreased to 59 microg/dL 21 days after the first course. The follow-up abdominal X-ray 20 days after the first examination was normal. Four months later, an outpatient follow-up visit showed a blood lead level within normal limits (14.5 microg/dL) and a psychiatric follow-up was initiated. Lead poisoning following the ingestion of lead-containing foreign bodies is particularly rare in adults, while it is sometimes observed in children. Pica behavior is a well-identified risk factor of lead intoxication in children but is quite exceptional in adults, where it is usually considered to be a psychiatric condition. Other unusual sources of lead poisoning include the ingestion of lead bullets, ceramic lead glaze or glazed earthenware, lead-contaminated candies, ethnic or herbal remedies.

  14. Ancient Ephesus: Processions as Media of Religious and Secular Propaganda

    Directory of Open Access Journals (Sweden)

    Lilian Portefaix

    1993-01-01

    Full Text Available The significance of religious rituals often reaches beyond their strict religious intentions. Specifically a procession, performed in front of the public, is a most effective instrument of disseminating a message to the crowds. Consequently, this ritual, as is well known, has often been used not only in religious but also in secular contexts; a procession under the cloak of religion can even become a politically useful medium to avoid popular disturbances on peaceful terms. This was the case in ancient Ephesus, where Roman power conflicted with Greek culture from the middle of the first century B.C. onwards. In the beginning of the second century A.D. the public religious life in the city of Ephesus was to a great extent characterized by processions relating to the cult of Artemis Ephesia. The one traditionally performed on the birthday of the goddess called to mind the Greek origin of the city; it was strictly associated with the religious sphere bringing about a close relationship between the goddess and her adherents. The other, artificially created by a Roman, was entirely secular, and spread its message every fortnight in the streets of Ephesus. It referred to the political field of action and intended to strengthen the Roman rule over the city. The Greek origin of Ephesian culture was later included in the message of the procession, reminding the Greeks not to rebel against Roman rule.

  15. Lead - nutritional considerations

    Science.gov (United States)

    ... billion people had toxic (poisonous) blood lead levels. Food Sources Lead can be found in canned goods if there is lead solder in the ... to bottled water for drinking and cooking. Avoid canned goods from foreign ... cans goes into effect. If imported wine containers have a lead foil ...

  16. Association of Lead Levels and Cerebral Palsy

    Science.gov (United States)

    Bansal, Neha; Aggarwal, Anju; Faridi, M. M. A.; Sharma, Tusha; Baneerjee, B. D.

    2017-01-01

    Background: Cerebral palsy is a common motor disability in childhood. Raised lead levels affect cognition. Children with cerebral palsy may have raised lead levels, further impairing their residual cognitive motor and behavioral abilities. Environmental exposure and abnormal eating habits may lead to increased lead levels. Aims and Objectives: To measure blood lead levels in children with cerebral palsy and compare them with healthy neurologically normal children. To correlate blood lead levels with environmental factors. Material and Methods: Design: Prospective case-control study. Setting: Tertiary care hospital. Participants: Cases comprised 34 children with cerebral palsy, and controls comprised 34 neurologically normal, age- and sex-matched children. Methods: Clinical and demographic details were recorded as per proforma. Detailed environmental history was recorded to know the source of exposure to lead. These children were investigated and treated as per protocol. Venous blood was collected in ethylenediaminetetraacetic acid vials for analysis of blood lead levels. Lead levels were estimated by Schimadzu Flame AA-6800 (atomic absorption spectrophotometer). Data were analyzed using SPSS version 17. P pica were 12.33 ± 10.02 µg/dL in comparison to children with no history of pica, 6.70 ± 4.60 µg/dL (P = .029). No correlation was found between hemoglobin and blood lead levels in cases and controls. Conclusion: In our study, blood lead levels are raised in children with cerebral palsy. However, further studies are required to show effects of raised levels in these children. PMID:28491920

  17. Situational influences of religious VS. secular symbols on cognition in Nigeria

    OpenAIRE

    Iruayenama, Mark, Abiye

    2016-01-01

    This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University London. Nigeria is constitutionally a secular country but its citizens are rated among the most religious in the world by several surveys. Religious symbolism is conspicuous in Nigeria, littered from educational institutions to work environments and market places. Semiotics and semantics have a rich history of the study of symbols, however, symbols are also utilized as primes in psycholog...

  18. 'Away' is a place: The impact of electronic waste recycling on blood lead levels in Ghana.

    Science.gov (United States)

    Amankwaa, Ebenezer Forkuo; Adovor Tsikudo, Kwame A; Bowman, Jay A

    2017-12-01

    E-waste recycling remains a major source of livelihood for many urban poor in developing countries, but this economic activity is fraught with significant environmental health risk. Yet, human exposure to the toxic elements associated with e-waste activities remains understudied and not evidently understood. This study investigates the impact of informal e-waste processing on the blood lead levels (BLLs) of e-waste workers and non-e-waste workers (mainly females working in activities that serve the Agbogbloshie e-waste site), and relates their lead exposure to socio-demographic and occupational characteristics. A total of 128 blood samples were analysed for lead levels. Surprisingly, the mean BLL (3.54μg/dL) of non-e-waste workers was slightly higher than that of e-waste workers (3.49μg/dL), although higher BLLs ranges were found among e-waste workers (0.50-18.80μg/dL) than non-e-waste workers (0.30-8.20μg/dL). Workers who engaged in e-waste burning tended to have the highest BLLs. In general, the BLLs are within the ABLES/US CDC reference level of 5μg/dL, although 12.3% of the workers have elevated BLLs, i.e. BLL ≥5μg/dL. The study concludes that the impact of e-waste recycling is not limited to workers alone. Traders and residents within the Agbogbloshie enclave are equally at risk through a range of environmental vectors. This calls for increased public awareness about the effects of human exposure to lead and other toxic elements from e-waste recycling. A key contribution is that government and stakeholder projects for safe e-waste infrastructure should disaggregate the e-waste value chain, recognize differential risk and resist one-size-fits-all strategies. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Environmental determinants of different blood lead levels in children: a quantile analysis from a nationwide survey.

    Science.gov (United States)

    Etchevers, Anne; Le Tertre, Alain; Lucas, Jean-Paul; Bretin, Philippe; Oulhote, Youssef; Le Bot, Barbara; Glorennec, Philippe

    2015-01-01

    Blood lead levels (BLLs) have substantially decreased in recent decades in children in France. However, further reducing exposure is a public health goal because there is no clear toxicological threshold. The identification of the environmental determinants of BLLs as well as risk factors associated with high BLLs is important to update prevention strategies. We aimed to estimate the contribution of environmental sources of lead to different BLLs in children in France. We enrolled 484 children aged from 6months to 6years, in a nationwide cross-sectional survey in 2008-2009. We measured lead concentrations in blood and environmental samples (water, soils, household settled dusts, paints, cosmetics and traditional cookware). We performed two models: a multivariate generalized additive model on the geometric mean (GM), and a quantile regression model on the 10th, 25th, 50th, 75th and 90th quantile of BLLs. The GM of BLLs was 13.8μg/L (=1.38μg/dL) (95% confidence intervals (CI): 12.7-14.9) and the 90th quantile was 25.7μg/L (CI: 24.2-29.5). Household and common area dust, tap water, interior paint, ceramic cookware, traditional cosmetics, playground soil and dust, and environmental tobacco smoke were associated with the GM of BLLs. Household dust and tap water made the largest contributions to both the GM and the 90th quantile of BLLs. The concentration of lead in dust was positively correlated with all quantiles of BLLs even at low concentrations. Lead concentrations in tap water above 5μg/L were also positively correlated with the GM, 75th and 90th quantiles of BLLs in children drinking tap water. Preventative actions must target household settled dust and tap water to reduce the BLLs of children in France. The use of traditional cosmetics should be avoided whereas ceramic cookware should be limited to decorative purposes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Transfusion of the dangerous universal donor blood leading to ...

    African Journals Online (AJOL)

    Background: In a health-care setting in which group-identical donor blood is not always available for transfusion, group O whole blood, in the obsolete concept of its being a universal donor, is sometimes given to group A and B recipients without necessary precautions. Objectives: The objective is to draw attention to the ...

  1. Shelley’s Unknown Eros: Post-Secular Love in Epipsychidion

    Directory of Open Access Journals (Sweden)

    Michael Tomko

    2016-09-01

    Full Text Available Whether Percy Bysshe Shelley’s Epipsychidion—a Platonic poem on love addressed to the patriarchally imprisoned Theresa Viviani or “Emily”—receives praise or blame has generally been determined by two focal passages: a secular sermon on free love and a planetary allegorical thinly veiling his own imbroglio. This essay re-reads Shelley’s 1821 work drawing on two recent arguments: Stuart Curran’s Dantean call to take the poem’s Florentine narrator seriously as a character, not just as an autobiographical cypher, and Colin Jager’s outline of Shelley’s move beyond the assumptions of his professed atheism after 1816. Based on the poem’s structure and imagery, the paper argues that Epipsychidion critiques the false sense of revolutionary ascent and dualistic escape offered to Emily, who is commodified and erased by the narrator’s egocentric, “counterfeit divinization of eros” (Benedict XVI. Turning from this Radical Enlightenment Platonism, the poem momentarily realizes an embodied, hylomorphic romantic union akin to the Christian nuptial mystery of two becoming “one flesh” (Mark 10:8. This ideal, however, collapses back into solipsism when the narrator cannot understand or accept love as a “unity in duality” (Benedict XVI. This paper thus claims Epipsychidion as a post-secular inquiry into the problem of love whose philosophic limits and theological horizons are both surprising and instructive. It also reclaims Shelley as a phenomenological poet who can open up the world to Christian and non-Christian readers, one whose Platonic and Dantean formation lend him an openness to transcendence and one whose countercultural path through life makes him wary of inhumane appropriations of religion.

  2. Delayed appearance of tracer lead in facial hair

    International Nuclear Information System (INIS)

    Rabinowitz, M.; Wetherill, G.; Kopple, J.

    1976-01-01

    Three adult men were fed 204 Pb--a rare, stable isotope of lead--daily for about 100 days. Simultaneous blood and facial hair measurements of this tracer and of total lead concentrations were made by mass spectrometric isotope dilution analysis. Although the blood showed an immediate response to the intake of the tracer, the facial hair showed a more gradual response and a delay of approximately 35 days. Since the pattern of appearance of lead in hair does not appear to represent a simple time delay of blood lead concentration, the existence of a physiological pool of lead fed by the blood and giving rise to the content in hair is suggested. Hair lead values should therefore, be interpreted as the integral of the blood lead values over the mean life of this intermediate pool--about 100 days

  3. Some studies of maternal and infant lead exposure in Glasgow

    Energy Technology Data Exchange (ETDEWEB)

    Moore, M.R.; Goldberg, A.; Pocock, S.J.; Meredith, A.; Stewart, I.M.; MacAnespie, H.; Lees, R.; Low, A.

    1982-04-01

    In two studies in the city of Glasgow, 236 mothers and their newly born infants and 117 mothers and their 6-weeks old children's environmental lead exposure were examined. In both studies blood lead concentrations were found to correlate significantly with the cube root of the domestic water lead concentrations. In the first study, multiple regression analyses of maternal blood lead and cord blood lead concentrations on other variables showed a significant negative correlation with gestational age. It was also noted that there was an annual fluctuation in maternal blood lead concentration with highest values in the autumn. In the second study, similar relationships were found. Although there was no association between blood lead and sex, age, place of birth or feeding method, as in the previous study, a significant association between social class and blood lead was found. This could be explained on the basis of the significant correlation between water lead and social class. In those mothers who breast fed, breast milk lead concentrations were found to correlate significantly with blood lead concentrations where breast milk lead was around one tenth of blood lead concentration. These studies emphasise the importance of water lead in the economy of environmental lead exposure to mothers and their unborn and newly born infants.

  4. Blood lead levels in pregnant women of high and low socioeconomic status in Mexico City.

    OpenAIRE

    Farias, P; Borja-Aburto, V H; Rios, C; Hertz-Picciotto, I; Rojas-Lopez, M; Chavez-Ayala, R

    1996-01-01

    This study examined the determinants of blood lead (BPb) in 513 pregnant women in Mexico City: 311 from public hospital prenatal clinics, representing primarily women of low socioeconomic status (SES), and 202 from private hospitals, primarily women of high SES. Overall, BPb levels ranged from 1.38 to 29 micrograms/dl, with geometric means of 6.7 and 11.12 micrograms/dl for women from private and public hospitals, respectively. The crude geometric means difference obtained by t-test was 4.42 ...

  5. The secular rise in IQs in the Netherlands: Is the Flynn Effect on g?

    NARCIS (Netherlands)

    te Nijenhuis, J.; van der Flier, H.

    2007-01-01

    IQ scores have been increasing over the last half century, a phenomenon known as the Flynn effect. In this study, we focused on the question to what extent these secular gains are on the g factor. Two IQ batteries: the Interest-School achievement-Intelligence Test (ISI) and the Groningen Final

  6. Religion, secular medicine and utilitarianism: a response to Biggar.

    Science.gov (United States)

    Smith, Kevin R

    2015-11-01

    Nigel Biggar has argued that religion ought to be given a seat at the negotiating table of medical ethics. I respond in broadly utilitarian terms, arguing that the flawed empirical basis, lack of rationality and non-universality inherent in religion disqualify it from ethical discourse. I conclude that while it would be unacceptable to attempt to debar religious individuals from the negotiating table, an exclusively secular approach is required for ethical decision making in medicine. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  7. Decreased blood hepatitis B surface antibody levels linked to e-waste lead exposure in preschool children

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Xijin [Laboratory of Environmental Medicine and Developmental Toxicology, and Guangdong Provincial Key Laboratory of Infectious Diseases, Shantou University Medical College, Shantou 515041, Guangdong (China); Department of Cell Biology and Genetics, Shantou University Medical College, Shantou 515041, Guangdong (China); Chen, Xiaojuan; Zhang, Jian [Laboratory of Environmental Medicine and Developmental Toxicology, and Guangdong Provincial Key Laboratory of Infectious Diseases, Shantou University Medical College, Shantou 515041, Guangdong (China); Guo, Pi [Department of Public Health, Shantou University Medical College, Shantou 515041, Guangdong (China); Fu, Tingzao; Dai, Yifeng [Laboratory of Environmental Medicine and Developmental Toxicology, and Guangdong Provincial Key Laboratory of Infectious Diseases, Shantou University Medical College, Shantou 515041, Guangdong (China); Lin, Stanley L. [Department of Pathophysiology and Key Immunopathology Laboratory of Guangdong Province, Shantou University Medical College, Shantou 515041, Guangdong (China); Huo, Xia, E-mail: xhuo@stu.edu.cn [Laboratory of Environmental Medicine and Developmental Toxicology, and Guangdong Provincial Key Laboratory of Infectious Diseases, Shantou University Medical College, Shantou 515041, Guangdong (China)

    2015-11-15

    Highlights: • Secondary exploratory analyses displayed a correlation of blood Pb to HBsAb levels. • Generalized linear mixed models were used to analyze two-phase data. • Children from an e-waste area had higher blood Pb levels and lower HBsAb titers. • Nearly 50% of Pb-exposed children fail to develop sufficient HBV immunity. • Different vaccination strategies are required for in e-waste areas. - Abstract: Lead (Pb) is a widespread environmental contaminant that can profoundly affect the immune system in vaccinated children. To explore the association between blood Pb and HBsAb levels in children chronically exposed to Pb, we measured hepatitis B surface antibody (HBsAb) titers, to reflect the immune response in the children of Guiyu, an electronic and electrical waste (e-waste) recycling area well known for environmental Pb contamination. We performed secondary exploratory analyses of blood Pb levels and plasma HBsAb titers in samples, taken in two phases between 2011 and 2012, from 590 children from Guiyu (exposed group) and Haojiang (reference group). Children living in the exposed area had higher blood Pb levels and lower HBsAb titers compared with children from the reference area. At each phase, generalized linear mixed models (GLMMs) showed that HBsAb titers were significantly negatively associated with child blood Pb levels. This work shows that a decreased immune response to hepatitis B vaccine and immune system might have potential harm to children with chronic Pb exposure. Importantly, nearly 50% of chronically exposed children failed to develop sufficient immunity to hepatitis in response to vaccination. Thus different vaccination strategies are needed for children living under conditions of chronic Pb exposure.

  8. Decreased blood hepatitis B surface antibody levels linked to e-waste lead exposure in preschool children

    International Nuclear Information System (INIS)

    Xu, Xijin; Chen, Xiaojuan; Zhang, Jian; Guo, Pi; Fu, Tingzao; Dai, Yifeng; Lin, Stanley L.; Huo, Xia

    2015-01-01

    Highlights: • Secondary exploratory analyses displayed a correlation of blood Pb to HBsAb levels. • Generalized linear mixed models were used to analyze two-phase data. • Children from an e-waste area had higher blood Pb levels and lower HBsAb titers. • Nearly 50% of Pb-exposed children fail to develop sufficient HBV immunity. • Different vaccination strategies are required for in e-waste areas. - Abstract: Lead (Pb) is a widespread environmental contaminant that can profoundly affect the immune system in vaccinated children. To explore the association between blood Pb and HBsAb levels in children chronically exposed to Pb, we measured hepatitis B surface antibody (HBsAb) titers, to reflect the immune response in the children of Guiyu, an electronic and electrical waste (e-waste) recycling area well known for environmental Pb contamination. We performed secondary exploratory analyses of blood Pb levels and plasma HBsAb titers in samples, taken in two phases between 2011 and 2012, from 590 children from Guiyu (exposed group) and Haojiang (reference group). Children living in the exposed area had higher blood Pb levels and lower HBsAb titers compared with children from the reference area. At each phase, generalized linear mixed models (GLMMs) showed that HBsAb titers were significantly negatively associated with child blood Pb levels. This work shows that a decreased immune response to hepatitis B vaccine and immune system might have potential harm to children with chronic Pb exposure. Importantly, nearly 50% of chronically exposed children failed to develop sufficient immunity to hepatitis in response to vaccination. Thus different vaccination strategies are needed for children living under conditions of chronic Pb exposure

  9. New Orleans before and after Hurricanes Katrina/Rita: a quasi-experiment of the association between soil lead and children's blood lead.

    Science.gov (United States)

    Zahran, Sammy; Mielke, Howard W; Gonzales, Christopher R; Powell, Eric T; Weiler, Stephan

    2010-06-15

    Prior to Hurricanes Katrina and Rita (HKR), significant associations were noted between soil lead (SL) and blood lead (BL) in New Orleans. Engineering failure of New Orleans levees and canal walls after HKR set the stage for a quasi-experiment to evaluate BL responses by 13 306 children to reductions in SL. High density soil surveying conducted in 46 census tracts before HKR was repeated after the flood. Paired t test results show that SL decreased from 328.54 to 203.33 mg/kg post-HKR (t = 3.296, p or =50% decrease in SL. Also individual BL in children was predicted as a function of SL, adjusting for age, year of observation, and depth of flood waters. At the individual scale, BL decreased significantly in post-HKR as a function of SL, with BL decreases ranging from b = -1.20 to -1.65 microg/dL, depending on the decline of SL and whether children were born in the post-HKR period. Our results support policy to improve soil conditions for children.

  10. Lead--still a health threat for marksmen.

    Science.gov (United States)

    Ochsmann, Elke; Göen, Thomas; Schaller, Karl-Heinz; Drexler, Hans

    2009-09-01

    Indoor shooting is a popular recreational activity all over the world. It is also a known source of exposure to lead fumes and dusts for the general, i.e. the non-occupationally exposed population. This study aimed at reporting the lead levels in blood of indoor shooters in Germany in association with personal behaviour at shooting ranges. Seven marksmen were examined via self-administered questionnaires. Lead level in blood (BLL) as well as airborne lead concentration (personal air sampling (PAS)) were detected. All measured blood lead levels (median: 290 microglead/L; range: 240-450 microglead/L) exceeded the values of the German general population (50 microg/L). Shooters sweeping the range after training seemed especially exposed (PAS: 7.14 mglead/m3). While extensive public effort is undertaken to prevent the general population from environmental lead exposure this short report gives reason to keep recreational shooting in mind when facing elevated blood lead levels or clinical symptoms possibly associated with lead intoxication.

  11. Milk siblingship, religious and secular: History, applications, and implications for practice.

    Science.gov (United States)

    Thorley, Virginia

    2014-12-01

    Milk kinship has religious and practical importance to Muslim families that is not well understood in Western cultures. The relationship occurs when an infant receives the milk of a woman other than the biological mother, creating familial relationships between the child and the woman whose milk is received. As milk siblings, her children and the recipient infant must never marry each other. Midwives in Western countries may encounter this in relation to human milk banking. This review provides a context for respectfully assisting families with their decision making when they are offered banked milk. A database search was conducted and other publications were found manually. Milk siblingship can be religious or secular. In Islam similar prohibitions on marriage exist to those for blood relations. The mothers therefore have to be known to each other to prevent an inappropriate marriage. This relationship has been a barrier to use of human milk banks by Muslim families as milk from several mothers is usually pooled. Nevertheless, donor milk has been used for premature neonates in two Islamic countries, applying the religious requirements. Recent interpretations by some Islamic scholars permitting milk banking may be acceptable to some families, but others will heed other rulings. NICU staff may encounter difficulties in providing banked human milk to infants from Muslim families. Different rulings exist and Muslim families in Western countries come from a variety of traditions. Sensitivity is required to explore these issues with families. Copyright © 2014 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  12. Lead sources in human diet in Greenland

    DEFF Research Database (Denmark)

    Bjerregaard, Peter; Johansen, Poul; Mulvad, Gert

    2004-01-01

    Although blood lead levels have declined in Greenland, they are still elevated despite the fact that lead levels in the Greenland environment are very low. Fragments of lead shot in game birds have been suggested as an important source of dietary exposure, and meals of sea birds, particularly eider......, contain high concentrations of lead. In a cross-sectional population survey in Greenland in 1993-1994, blood lead adjusted for age and sex was found to be associated with the reported consumption of sea birds. Participants reporting less than weekly intake of sea birds had blood lead concentrations...... of approximately 75 microg/L, whereas those who reported eating sea birds several times a week had concentrations of approximately 110 microg/L, and those who reported daily intake had concentrations of 170 microg/L (p = 0.01). Blood lead was not associated with dietary exposure to other local or imported food...

  13. Gain-of-function somatic mutations contribute to inflammation and blood vessel damage that lead to Alzheimer dementia: a hypothesis.

    Science.gov (United States)

    Marchesi, Vincent T

    2016-02-01

    Amyloid deposits are a characteristic feature of advanced Alzheimer dementia (AD), but whether they initiate the disease or are a consequence of it remains an unsettled question. To explore an alternative pathogenic mechanism, I propose that the triggering events that begin the pathogenic cascade are not amyloid deposits but damaged blood vessels caused by inflammatory reactions that lead to ischemia, amyloid accumulation, axonal degeneration, synaptic loss, and eventually irreversible neuronal cell death. Inflammation and blood vessel damage are well recognized complications of AD, but what causes them and why the cerebral microvasculature is affected have never been adequately addressed. Because heritable autosomal dominant mutations of NLRP3, APP, TREX1, NOTCH3, and Col4A1 are known to provoke inflammatory reactions and damage the brain in a wide variety of diseases, I propose that one or more low abundant, gain-of-function somatic mutations of the same 5 gene families damage the microvasculature of the brain that leads to dementia. This implies that the pathogenic triggers that lead to AD are derived not from external invaders or amyloid but from oxidative damage of our own genes. © FASEB.

  14. Association of childhood blood-lead levels with cognitive function and socioeconomic status at age 38 years and with IQ change and socioeconomic mobility between childhood and adulthood

    Science.gov (United States)

    Reuben, Aaron; Caspi, Avshalom; Belsky, Daniel W.; Broadbent, Jonathan; Harrington, Honalee; Sugden, Karen; Houts, Renate M.; Ramrakha, Sandhya; Poulton, Richie; Moffitt, Terrie E.

    2017-01-01

    Importance Many children in the US and around the world are exposed to lead, a developmental neurotoxin. The long-term cognitive and socioeconomic consequences of lead exposure are uncertain. Objective To test the hypothesis that childhood lead exposure is associated with cognitive function and socioeconomic status in adulthood and with changes in IQ and socioeconomic mobility between childhood and midlife. Design, Setting, and Participants Prospective cohort study based on a population-representative 1972–73 birth cohort from New Zealand, the Dunedin Multidisciplinary Health and Development Study, followed to age 38 years (December, 2012). Exposure Childhood lead exposure ascertained as blood-lead levels measured at 11 years. High blood-lead levels were observed among children from all socioeconomic status levels in this cohort. Main Outcomes and Measures The IQ (primary outcome) and indexes of Verbal Comprehension, Perceptual Reasoning, Working Memory, and Processing Speed (secondary outcomes) were assessed at 38 years using the Wechsler Adult Intelligence Scale–IV (WAIS-IV; IQ range 40–160). Socioeconomic status (primary outcome) was assessed at 38 years using the New Zealand Socioeconomic Index-2006, (NZSEI-06; range 10=lowest-90=highest). Results Of 1037 original participants, 1007 were alive at 38 years, of whom 565 (56%) had been lead tested at 11 years (54% male; 93% white). Mean blood-lead level at 11 years was 10.99μg/dL (SD=4.63). Among blood-tested participants included at 38 years, mean WAIS-IV score was 101.16 (SD=14.82) and mean NZSEI-06 score was 49.75 (SD=17.12). After adjusting for maternal IQ, childhood IQ, and childhood socioeconomic status, each 5μg/dL higher level of blood-lead in childhood was associated with a 1.61-point lower score (95%CI:−2.48, −0.74) in adult IQ, a 2.07-point lower score (95%CI: −3.14, −1.01) in Perceptual Reasoning, and a 1.26-point lower score (95%CI: −2.38, −0.14) in Working Memory. Lead

  15. Assessment of blood lead level declines in an area of historical mining with a holistic remediation and abatement program.

    Science.gov (United States)

    Schoof, Rosalind A; Johnson, Dina L; Handziuk, Emma R; Landingham, Cynthia Van; Feldpausch, Alma M; Gallagher, Alexa E; Dell, Linda D; Kephart, Amy

    2016-10-01

    Lead exposure and blood lead levels (BLLs) in the United States have declined dramatically since the 1970s as many widespread lead uses have been discontinued. Large scale mining and mineral processing represents an additional localized source of potential lead exposure in many historical mining communities, such as Butte, Montana. After 25 years of ongoing remediation efforts and a residential metals abatement program that includes blood lead monitoring of Butte children, examination of blood lead trends offers a unique opportunity to assess the effectiveness of Butte's lead source and exposure reduction measures. This study examined BLL trends in Butte children ages 1-5 (n= 2796) from 2003-2010 as compared to a reference dataset matched for similar demographic characteristics over the same period. Blood lead differences across Butte during the same period are also examined. Findings are interpreted with respect to effectiveness of remediation and other factors potentially contributing to ongoing exposure concerns. BLLs from Butte were compared with a reference dataset (n=2937) derived from the National Health and Nutrition Examination Survey. The reference dataset was initially matched for child age and sample dates. Additional demographic factors associated with higher BLLs were then evaluated. Weights were applied to make the reference dataset more consistent with the Butte dataset for the three factors that were most disparate (poverty-to-income ratio, house age, and race/ethnicity). A weighted linear mixed regression model showed Butte geometric mean BLLs were higher than reference BLLs for 2003-2004 (3.48vs. 2.05µg/dL), 2005-2006 (2.65vs. 1.80µg/dL), and 2007-2008 (2.2vs. 1.72µg/dL), but comparable for 2009-2010 (1.53vs. 1.51µg/dL). This trend suggests that, over time, the impact of other factors that may be associated with Butte BLLs has been reduced. Neighborhood differences were examined by dividing the Butte dataset into the older area called "Uptown

  16. Exploring the determinants of secular decreases in dental caries among Korean children.

    Science.gov (United States)

    Lee, Hye-Ju; Han, Dong-Hun

    2015-08-01

    The aim of this study was to determine the contributions of sealant and water fluoridation to the time trends in dental caries from 2003 to 2010. Data were from three waves of the Korean National Oral Health Surveys between 2003 and 2010, including a total of 23 059 children (11 889 boys and 11 170 girls) aged 8, 10, and 12 years. The impacts of sealant and water fluoridation on dental caries were obtained by logistic regression for each age group of children. The contributions of sealant and water fluoridation to the time trends in the prevalence of dental caries were examined by a series of logistic regression models, and changes in the adjusted odds ratios for each survey year were also calculated. Over the past 7 years, the prevalence of dental caries decreased dramatically. Although sealant had a significant impact on dental caries in each survey year, remarkable decreases in dental caries from 2003 to 2010 were not explained by the secular changes in the dental sealant or water fluoridation factor. We observed important population declines in dental caries in Korea in children aged 8-12 years; however, the likely causes for these secular trends remain to be determined. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Importance of selecting archaeomagnetic data for geomagnetic modelling: example of the new Western Europe directional and intensity secular variation curves from 1500 BC to 200 AD

    Science.gov (United States)

    Herve, Gwenael; Chauvin, Annick; Lanos, Philippe

    2014-05-01

    At the regional scale, the dispersion between archaeomagnetic data and especially archaeointensities suggests that some of them may be biased. As a consequence, it appears necessary to perform a selection of available data before to compute mean regional secular variation curves or geomagnetic models. However the definition of suitable selection criteria is not obvious and we need to know how to manage "old" data acquired during the 60-70s. The Western Europe directional and intensity data set from 1500 BC to 200 AD allows to discuss these issues. It has recently been enhanced by 39 new archaeodirections and 23 new archaeointensities (Hervé et al., 2013a and 2013b data sets and 5 unpublished data). First, the whole Western Europe data set was selected but the strong dispersion restricted the accuracy and the reliability of the new Western Europe secular variation curves at Paris. The causes of the dispersion appear different between archaeodirections and archaeointensities. In the directional data set, the main problem comes from some age errors in the oldest published data. Since their publication their archaeological dating may have changed of 50 years or more. For intensity data that were acquired much more recently, the dispersion mainly results from the use of unreliable archaeointensity protocols. We propose a weighting approach based on the number of specimens and the use of pTRM-checks, anisotropy and cooling rate corrections. Only 63% of available archaeodirections and 32% of archaeointensities were used to build the new Western Europe secular variation curves from 1500 BC to 200 AD. These curves reveal that selecting the reference data avoids wrong estimations of the shape of the secular variation curves, the secular variation rate, the dating of archaeomagnetic jerks... Finally, it is worth pointing out that current geomagnetic global models take into account almost all the data that we decided to reject. It could partly explain why their predictions at

  18. Release of lead from bone in pregnancy and lactation

    International Nuclear Information System (INIS)

    Manton, W.I.; Angle, C.R.; Stanek, K.L.; Kuntzelman, D.; Reese, Y.R.; Kuehnemann, T.J.

    2003-01-01

    Concentrations and isotope ratios of lead in blood, urine, 24-h duplicate diets, and hand wipes were measured for 12 women from the second trimester of pregnancy until at least 8 months after delivery. Six bottle fed and six breast fed their infants. One bottle feeder fell pregnant for a second time, as did a breast feeder, and each was followed semicontinuously for totals of 44 and 54 months, respectively. Bone resorption rather than dietary absorption controls changes in blood lead, but in pregnancy the resorption of trabecular and cortical bone are decoupled. In early pregnancy, only trabecular bone (presumably of low lead content) is resorbed, causing blood leads to fall more than expected from hemodilution alone. In late pregnancy, the sites of resorption move to cortical bone of higher lead content and blood leads rise. In bottle feeders, the cortical bone contribution ceases immediately after delivery, but any tendency for blood leads to fall may be compensated by the effect of hemoconcentration produced by the postpartum loss of plasma volume. In lactation, the whole skeleton undergoes resorption and the blood leads of nursing mothers continue to rise, reaching a maximum 6-8 months after delivery. Blood leads fall from pregnancy to pregnancy, implying that the greatest risk of lead toxicity lies with first pregnancies

  19. Lead toxicity on hematological parameters in workers with occupational exposure to lead

    International Nuclear Information System (INIS)

    Dursun, N.; Koese, K.

    1998-01-01

    The effects of lead on hematological parameters were studied in lead exposed male workers occupied for 17.84+-4.22 years in a metal powder producing factory in Kayseri, Turkey and control male workers in same city. Blood lead and plasma zinc levels were measured by Atomic Absorption Spectrophotometry (AAS) and hematological parameters by Culture Counter S. The lead exposure workers had higher lead levels (13.81+- 9.21 mug/dl) as compared to control subjects (2.37+-0.10 mug/dl). No difference was observed in the plasma zinc levels of both groups. As indices of lead exposure, red blood cell (RBC) counts, hemoglobin (Hb), and hematocrit (Hct) values significantly decreased. Mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC) significantly increased except MCV. There was also an increase in MCV, but it was not significant. (author)

  20. Chronic Lead Intoxication From Eating Wild-Harvested Game.

    Science.gov (United States)

    Buenz, Eric J; Parry, Gareth J

    2018-05-01

    The purpose of this article is to determine if conversion from eating wild game harvested with lead-based ammunition to nonlead-based ammunition results in lower blood lead levels. Supersonic injection of toxin-leeching frangible projectiles into food is intuitively bad. As much as 95% of the ~13.7 million hunters in the United States choose shrapnel-inducing lead bullets to kill game; in addition, not harvesting meat is an incarcerable crime. A lead ammunition ban on certain federal lands was recently rescinded and the National Rifle Association refutes any risk from eating lead bullet-harvested game. A patient subsisting solely on lead-shot meat was converted to non-lead ammunition and his blood lead level tracked. Concomitant with his conversion to nonlead ammunition, a controlled experiment was performed using the patient's bullets to determine his daily lead intake from lead-shot meat. While eating lead-shot meat, the patient was consuming 259.3 ± 235.6 µg of lead daily and his blood lead level was 74.7 µg/dL. Conversion to nonlead ammunition was associated with a reduced blood lead level. Unsafe blood lead levels can occur from eating game harvested with lead ammunition. Physicians should warn hunting patients of this potential risk and counsel them about the availability of nonlead ammunition alternatives. Copyright © 2018 Elsevier Inc. All rights reserved.