WorldWideScience

Sample records for blood establishments revised

  1. Blood Establishment Registration Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — This application provides information for active, inactive, and pre-registered firms. Query options are by FEI, Applicant Name, Establishment Name, Other Names,...

  2. 77 FR 7 - Revisions to Labeling Requirements for Blood and Blood Components, Including Source Plasma

    Science.gov (United States)

    2012-01-03

    ...) Revisions to Labeling Requirements for Blood and Blood Components, Including Source Plasma AGENCY: Food and... requirements for blood and blood components, including Source Plasma, into one section of the Code of Federal..., and Source Plasma,'' which amended Sec. 606.121(d)(2) by adding ``or in solid black,''...

  3. Revisions to labeling requirements for blood and blood components, including source plasma. Final rule.

    Science.gov (United States)

    2012-01-03

    The Food and Drug Administration (FDA) is revising the labeling requirements for blood and blood components intended for use in transfusion or for further manufacture by combining, simplifying, and updating specific regulations applicable to labeling and circulars of information. These requirements will facilitate the use of a labeling system using machine-readable information that would be acceptable as a replacement for the ``ABC Codabar'' system for the labeling of blood and blood components. FDA is taking this action as a part of its efforts to comprehensively review and, as necessary, revise its regulations, policies, guidances, and procedures related to the regulation of blood and blood components. This final rule is intended to help ensure the continued safety of the blood supply and facilitate consistency in labeling.

  4. 75 FR 8045 - National Environmental Policy Act (NEPA) Draft Guidance, Establishing, Applying, and Revising...

    Science.gov (United States)

    2010-02-23

    ... QUALITY National Environmental Policy Act (NEPA) Draft Guidance, Establishing, Applying, and Revising Categorical Exclusions Under the National Environmental Policy Act AGENCY: Council on Environmental Quality... Exclusions Under the National Environmental Policy Act.'' SUMMARY: On February 18, 2010, the Council...

  5. A rational framework for production decision making in blood establishments.

    Science.gov (United States)

    Ramoa, Augusto; Maia, Salomé; Lourenço, Anália

    2012-07-24

    SAD_BaSe is a blood bank data analysis software, created to assist in the management of blood donations and the blood production chain in blood establishments. In particular, the system keeps track of several collection and production indicators, enables the definition of collection and production strategies, and the measurement of quality indicators required by the Quality Management System regulating the general operation of blood establishments. This paper describes the general scenario of blood establishments and its main requirements in terms of data management and analysis. It presents the architecture of SAD_BaSe and identifies its main contributions. Specifically, it brings forward the generation of customized reports driven by decision making needs and the use of data mining techniques in the analysis of donor suspensions and donation discards.

  6. Quality Assessment of Established and Emerging Blood Components for Transfusion

    Directory of Open Access Journals (Sweden)

    Jason P. Acker

    2016-01-01

    Full Text Available Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma. Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation.

  7. Quality Assessment of Established and Emerging Blood Components for Transfusion

    Science.gov (United States)

    Marks, Denese C.

    2016-01-01

    Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma). Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation. PMID:28070448

  8. Quality Assessment of Established and Emerging Blood Components for Transfusion.

    Science.gov (United States)

    Acker, Jason P; Marks, Denese C; Sheffield, William P

    2016-01-01

    Blood is donated either as whole blood, with subsequent component processing, or through the use of apheresis devices that extract one or more components and return the rest of the donation to the donor. Blood component therapy supplanted whole blood transfusion in industrialized countries in the middle of the twentieth century and remains the standard of care for the majority of patients receiving a transfusion. Traditionally, blood has been processed into three main blood products: red blood cell concentrates; platelet concentrates; and transfusable plasma. Ensuring that these products are of high quality and that they deliver their intended benefits to patients throughout their shelf-life is a complex task. Further complexity has been added with the development of products stored under nonstandard conditions or subjected to additional manufacturing steps (e.g., cryopreserved platelets, irradiated red cells, and lyophilized plasma). Here we review established and emerging methodologies for assessing blood product quality and address controversies and uncertainties in this thriving and active field of investigation.

  9. Ovine blood: establishment of a list of reference values relevant for blood coagulation in sheep.

    Science.gov (United States)

    Wilhelmi, Mathias H; Tiede, Andreas; Teebken, Omke E; Bisdas, Theodosios; Haverich, Axel; Mischke, Reinhard

    2012-01-01

    Ovine animal models are widely used to conduct preclinical studies, e.g., to evaluate cardiovascular prostheses intended to be applied in man. However, although analyzed in many of those studies, information about ovine blood reference values is scanty. The aim of this study is to establish a reference list of ovine blood parameters relevant for blood coagulation. A cohort of 47 mature ewes was evaluated. Parameters comprised the following: cells and cellular components-platelet, red, and white cell counts (including subsets), hemoglobin (Hb), hematocrit (HCT), mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV), and MCH concentration (MCHC); global tests of coagulation-prothrombin time (Quick's time) and activated partial thromboplastin time (aPTT); and parameters relevant for blood coagulation-fibrinogen, antithrombin (AT), and von Willebrand Factor. After explorative data analysis, a list of ovine reference values was established. Interestingly, a comparison with human reference values revealed some interspecies differences between sheep and man, i.e., much higher ovine ranges for some cell counts (neutrophils, lymphocytes, basophils, eosinophils, and platelets) but lower values for some other parameters (Hb, HCT, MCV, MCH, AT, and Quick's test). We established a reference list of ovine blood count and blood coagulation parameters. Because of some peculiarities of the ovine blood, this list may have implications for the interpretation of experimental data.

  10. 78 FR 18353 - Guidance for Industry: Blood Establishment Computer System Validation in the User's Facility...

    Science.gov (United States)

    2013-03-26

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry: Blood Establishment Computer System... ``Guidance for Industry: Blood Establishment Computer System Validation in the User's Facility'' dated April... establishment computer system validation program, consistent with recognized principles of software...

  11. 75 FR 17202 - Proposed Establishment of Long Beach, CA, Class C Airspace Area and Revision of Santa Ana (John...

    Science.gov (United States)

    2010-04-05

    ... Revision of Santa Ana (John Wayne), CA, Class C Airspace Area; Public Meetings AGENCY: Federal Aviation... establish Class C airspace at Long Beach, CA, and revise the Santa Ana (John Wayne) Class C airspace area... Santa Ana (John Wayne), CA, Class C airspace area will be accepted. (b) The meetings will be open to...

  12. 77 FR 6463 - Revisions to Labeling Requirements for Blood and Blood Components, Including Source Plasma...

    Science.gov (United States)

    2012-02-08

    ... Requirements for Blood and Blood Components, Including Source Plasma; Correction AGENCY: Food and Drug... Blood Components, Including Source Plasma,'' which provided incorrect publication information...

  13. [How do I assess requirement of a blood bank and its kind for a healthcare establishment?].

    Science.gov (United States)

    Lafeuillade, B; Tixier, A; Bliem, C; Meyer, F

    2014-12-01

    Access to blood components is required for healthcare establishments, particularly for emergency situation and hospital blood bank was often a response to this requirement. However, the complexity of regulation and economic pressures lead healthcare establishment to review regularly their need for a blood bank. This assessment requires analysis of need for transfusions in terms of delay, quantity and clinical situations to which they must respond. When a blood bank is required, three kinds could be under consideration: emergency blood bank, intermediate blood bank and issuance blood bank. According to requirements, advantages and disadvantages of each kind, healthcare establishments would select the most suitable one.

  14. Revised

    DEFF Research Database (Denmark)

    Johannsen, Vivian Kvist; Nord-Larsen, Thomas; Riis-Nielsen, Torben;

    This report is a revised analysis of the Danish data on CO2 emissions from forest, afforestation and deforestation for the period 1990 - 2008 and a prognosis for the period until 2020. Revision have included measurements from 2009 in the estimations. The report is funded by the Ministry of Climate...

  15. Establishing the diffuse correlation spectroscopy signal relationship with blood flow.

    Science.gov (United States)

    Boas, David A; Sakadžić, Sava; Selb, Juliette; Farzam, Parisa; Franceschini, Maria Angela; Carp, Stefan A

    2016-07-01

    Diffuse correlation spectroscopy (DCS) measurements of blood flow rely on the sensitivity of the temporal autocorrelation function of diffusively scattered light to red blood cell (RBC) mean square displacement (MSD). For RBCs flowing with convective velocity [Formula: see text], the autocorrelation is expected to decay exponentially with [Formula: see text], where [Formula: see text] is the delay time. RBCs also experience shear-induced diffusion with a diffusion coefficient [Formula: see text] and an MSD of [Formula: see text]. Surprisingly, experimental data primarily reflect diffusive behavior. To provide quantitative estimates of the relative contributions of convective and diffusive movements, we performed Monte Carlo simulations of light scattering through tissue of varying vessel densities. We assumed laminar vessel flow profiles and accounted for shear-induced diffusion effects. In agreement with experimental data, we found that diffusive motion dominates the correlation decay for typical DCS measurement parameters. Furthermore, our model offers a quantitative relationship between the RBC diffusion coefficient and absolute tissue blood flow. We thus offer, for the first time, theoretical support for the empirically accepted ability of the DCS blood flow index ([Formula: see text]) to quantify tissue perfusion. We find [Formula: see text] to be linearly proportional to blood flow, but with a proportionality modulated by the hemoglobin concentration and the average blood vessel diameter.

  16. 21 CFR 607.7 - Establishment registration and product listing of blood banks and other firms manufacturing human...

    Science.gov (United States)

    2010-04-01

    ... blood banks and other firms manufacturing human blood and blood products. 607.7 Section 607.7 Food and... Provisions § 607.7 Establishment registration and product listing of blood banks and other firms... permit any blood bank or similar establishment to ship blood products in interstate commerce. (b)...

  17. Tranexamic Acid in a Multimodal Blood Loss Prevention Protocol to Decrease Blood Loss in Revision Total Knee Arthroplasty: A Cohort Study#

    Science.gov (United States)

    Ortega-Andreu, Miguel; Talavera, Gloria; Padilla-Eguiluz, Norma G.; Perez-Chrzanowska, Hanna; Figueredo-Galve, Reyes; Rodriguez-Merchán, Carlos E.; Gómez-Barrena, Enrique

    2016-01-01

    Purpose: To clarify if blood loss and transfusion requirements can be decreased in revision knee surgery through a multimodal blood loss approach with tranexamic acid (TXA) Patients and Methods: A retrospective study was designed in 87 knees (79 patients) that received a knee revision between 2007 and 2013. To avoid heterogeneity in the surgical technique, only revisions with one single implant system were included. A treatment series of 44 knees that received TXA and other techniques in a multimodal blood loss protocol was compared to a control series of 43 knees that received neither TXA nor the rest of the multimodal blood loss protocol. No differences in the complexity of surgeries or case severity were detected. Results: A significant decrease was observed from 58% transfusion rate in the control group to 5% in the treated group. The postoperative haemoglobin drop was also significantly different. Although the use of a blood loss prevention approach including TXA was the most relevant factor in the transfusion risk (OR=15), longer surgical time also associated an increased risk of transfusion (OR=1.15). Conclusion: This study supports the use of a two-dose intravenous TXA under a multimodal blood loss prevention approach in revision knee replacement with significant reduction in the transfusion rate, postoperative blood loss and haemoglobin drop. PMID:27708740

  18. No Effect of a Bipolar Sealer on Total Blood Loss or Blood Transfusion in Nonseptic Revision Knee Arthroplasty-A Prospective Study With Matched Retrospective Controls

    DEFF Research Database (Denmark)

    Nielsen, Christian Skovgaard; Gromov, Kirill; Jans, Øivind;

    2017-01-01

    BACKGROUND: Postoperative anemia is frequent after revision of total knee arthroplasty (TKA) with reported transfusion rates up to 83%. Despite increased efforts of reducing blood loss and enhancing fast recovery within the fast-track setup, a considerable transfusion rate is still evident. The a...

  19. Importance of monitoring family members in establishing sources and pathways of lead in blood.

    Science.gov (United States)

    Gulson, B L; Mizon, K J; Korsch, M J; Howarth, D

    1996-10-11

    High precision lead isotope measurements were undertaken to establish the sources and pathways in blood and environmental samples of five families from the Broken Hill lead mining community, New South Wales, Australia. The five families were selected from 27 families investigated to illustrate the different sources and pathways of lead into blood and the importance of monitoring the whole family. The results illustrate that although the major source of lead is from the orebody, paint and petrol can be significant contributors to both house dust and blood leads. The results also show that the sources and pathways can be from the father's occupation and hence monitoring of families is important, especially in high risk locations. In two cases, the elevated blood leads in the children did not derive from their current residence but from other residences in the community.

  20. Establishment of a molecular tool for blood meal identification in Malaysia

    Institute of Scientific and Technical Information of China (English)

    Ernieenor Faraliana Che Lah; Mariana Ahamad; Mohd Subail Haron; Ho Tze Ming

    2012-01-01

    Objective: To establish a polymerase chain reaction (PCR) technique based on cytochrome b (cytb) gene of mitochondria DNA (mtDNA) for blood meal identification. Methods: The PCR technique was established based on published information and validated using blood sample of laboratory animals of which their whole gene sequences are available in GenBank. PCR was next performed to compile gene sequences of different species of wild rodents. The primers used were complementary to the conserved region of the cytb gene of vertebrate’s mtDNA. A total of 100 blood samples, both from laboratory animals and wild rodents were collected and analyzed. The obtained unknown sequences were compared with those in the GenBank database using BLAST program to identify the vertebrate animal species. Results: Gene sequences of 11 species of wild animals caught in 9 localities of Peninsular Malaysia were compiled using the established PCR. The animals involved were Rattus (rattus) tanezumi, Rattus tiomanicus, Leopoldamys sabanus,Tupaia glis, Tupaia minor, Niviventor cremoriventor, Rhinosciurus laticaudatus, Callosciurus caniseps, Sundamys muelleri, Rattus rajah and Maxomys whiteheadi. The BLAST results confirmed the host with exact or nearly exact matches (>89% identity). Ten new gene sequences have been deposited in GenBank database since September 2010. Conclusions: This study indicates that the PCR direct sequencing system using universal primer sets for vertebrate cytb gene is a promising technique for blood meal identification.

  1. Reference values of fetal erythrocytes in maternal blood during pregnancy established using flow cytometry.

    Science.gov (United States)

    de Wit, Harry; Nabbe, Karin C A M; Kooren, Jurgen A; Adriaansen, Henk J; Roelandse-Koop, Elianne A; Schuitemaker, Joost H N; Hoffmann, Johannes J M L

    2011-10-01

    The aim of our study was to assess the fetal RBC count in maternal blood during uncomplicated pregnancies from 26 weeks onward. We used a flow cytometric method specifically designed for use in a routine hematology analyzer. Pregnant women were recruited through midwives. The participating laboratories used the FMH QuikQuant method (Trillium Diagnostics, Brewer, ME) in a CELL-DYN Sapphire hematology analyzer (Abbott Diagnostics, Santa Clara, CA). The method is based on a monoclonal antibody to hemoglobin F. Flow cytometric data were analyzed by 2 independent observers. The 95th percentile reference range was estimated according to Clinical and Laboratory Standards Institute guidelines. A total of 236 samples were statistically analyzed. Gestational ages ranged from 21.6 to 41 weeks (mean, 32.0 weeks), and the fetal RBC count in maternal blood ranged from 0.00% to 0.50% (median, 0.025%). The fetal RBC count in maternal blood shows no correlation with gestational age. The established reference range during normal pregnancy is less than 0.125%.

  2. Pilot social feasibility study for the establishment of a public human umbilical cord blood stem cell bank in South Africa.

    Science.gov (United States)

    Meissner-Roloff, Madelein; Young, Wendy; Rangaka, Isabella; Lombaard, Hennie; Dhai, Ames; Tsotsi, Norma; Pepper, Michael S

    2012-12-01

    There is a large unmet need in South Africa for bone marrow transplantation. Umbilical cord blood (UCB) is an important source of stem cells for the treatment of haematological and non-haematological diseases. Access to the two existing private umbilical cord blood stem cell banks (UCB SCBs) in South Africa is limited to individuals that can afford it, which further aggravates the ever increasing divide between families from different socio-economic classes. The problem is compounded by a severe global shortage of genetically compatible samples, representative of the South African demographics. Establishing a public human UCB SCB in South Africa would provide more South Africans with access to previously unavailable treatment in the form of affordable, genetically compatible stem cells for bone marrow transplantation. A public UCB SCB has many facets to consider, one of which is public preparedness and support for the bank. This was assessed in a social feasibility pilot study which is reported here. In addition to the findings of this social feasibility study, other important considerations for establishing a public human UCB SCB in SA include; (a) testing the samples for HIV and other infectious diseases (required for compliance with international regulatory standards); (b) flow cytometric analysis for enumeration of CD34+ UCB stem cells; (c) mapping of HLA genotypes/alleles; and (d) a study of the economic feasibility of this endeavour.The social feasibility study was conducted to gauge public preparedness and support for a public SCB through patient interviews and questionnaires. The process was dynamic due to its novel nature for interviewers and interviewees alike. Many obstacles were met and dealt with which lead to the compilation of results discussed here in the form of a pilot social feasibility study.In the South African context, we are faced with unique and rich challenges relating to cultural and religious differences that are further augmented by

  3. [Molecular mechanism for the establishment of blood-vessel gateway for immune cells in the CNS.

    Science.gov (United States)

    Murakami, Masaaki

    2017-01-01

    We have been studying about the molecular mechanism responsible for the establishment of the blood-vessel gateway through which immune cells enter the CNS. We have discovered three kinds of gateways in a multiple sclerosis model, EAE, based on the neural stimulations and named them the gravity-gateway reflex, electric-gateway reflex, and pain-gateway reflex, respectively. All gateway reflexes are involved in specific crosstalk between sensory-sympathetic pathways. For example, in the gravity-gateway reflex, gravity-mediated sensory stimulation via the soleus muscles activates fifth lumber(L5)dorsal loot ganglions to activate L5 sympathetic ganglions, which express norepinephrine at specific vessels of the L5 cord. We explain these three types of gateway reflexes in this chapter.

  4. Bypassing the blood-brian barrier using established skull base reconstruction techniques

    Institute of Scientific and Technical Information of China (English)

    Marcel M.Miyake; Benjamin S.Bleier

    2015-01-01

    Background: Neurological disorders represent a profound healthcare problem accounting for 6.3% of the global disease burden.Alzheimer's disease alone is expected to impact over 115 million people worldwide by 2050 with a cost of over $1 trillion per year to the U.S.economy.Despite considerable advances in our understanding of the pathogenesis and natural history of neurological disorders, the development of disease modifying therapies have failed to keep pace.This lack of effective treatments is directly attributable to the presence of the blood-brain and blood-cerebrospinal fluid barriers (BBB and BCSFB) which prevent up to 98% of all potential neuropharmaceutical agents from reaching the central nervous system (CNS).These obstacles have thereby severely limited research and development into novel therapeutic strategies for neurological disease.Current experimental methods to bypass the BBB, including pharmacologic modification and direct transcranial catheter implantation, are expensive, are associated with significant complications, and cannot be feasibly scaled up to meet the chronic needs of a large, aging patient population.Transmucosal drug delivery: An innovative method of direct CNS drug delivery using heterotopic mucosal grafts was described.This method is based on established endoscopic skull base nasoseptal flap reconstruction techniques.The model has successfully demonstrated CNS delivery of chromophore-tagged molecules 1000 times larger than those typically permitted by the BBB.Conclusions: This innovative technique represents the first described method of permanently bypassing the blood-brain barrier using purely autologous tissues.This has the potential to dramatically improve the current treatment of neurological disease by providing a safe and chronic transnasaldelivery pathway for high molecular weight neuropharmaceuticals.

  5. A study on the establishment of a standard nuclear cooperation agreement and the revision of existing nuclear cooperation agreements in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Keun Bae; Lee, K. S.; Lee, D. J.; Lee, B. Y.; Cho, I. H.; Ko, H. S.

    1997-04-01

    The objectives of this study are to suggest a standard nuclear cooperation agreement (SNCA) as a model for new nuclear cooperation agreements (NCA`s) which are expected to be concluded in the near future and to suggest a proposal text and strategy for the revision of existing NCA`s with advanced countries such as the United States. To accomplish the objectives, this study: First, establishes a framework for a NCA through clarifying the basic concept of NCA and identifying key elements of NCA. Second, draws implications for a standard NCA and revision of existing NCA`s through analyzing by comparison those NCA`s between other countries. Third, clarifies the purpose and underlying philosophy for the SNCA, determines the elements to be included in the SNCA, and suggests a final draft of the SNCA. And fourth, clarifies general concepts of the revision of NCA`s, analyzes the needs of the revision of the Korea-U.S. NCA, and assesses the position of the United States on the matter. (author). 28 refs., 5 tabs., 2 figs.

  6. Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature 1

    Science.gov (United States)

    Wilson, Ana Maria Miranda Martins; Peterlini, Maria Angélica Sorgini; Pedreira, Mavilde da Luz Gonçalves

    2016-01-01

    ABSTRACT Objectives: to obtain information from scientific literature concerning infusion pumps used in administering erythrocyte (red blood cells) and to evaluate the implications in the practical use of this equipment by nurses when conducting transfusions. Method: an integrative revision of the following scientific databases: Pubmed/Medline, Scopus, the Virtual Library for Health, SciELO, Web of Science and Cochrane. The following descriptors were used: "infusion pumps", "blood transfusion", "transfused erythrocyte" and "hemolyis". There were no restrictions on the scope of the initial data and it was finalized in December 2014. 17 articles were identified in accordance with the inclusion and exclusion criteria. Results: all of the publications included in the studies were experimental in vitro and covered the use of infusion pumps in transfusion therapy. A summary of the data was presented in a synoptic chart and an analysis of it generated the following categories: cellular damage and the infusion mechanism. Conclusion: infusion pumps can be harmful to erythrocytes based on the infusion mechanism that is used, as the linear peristaltic pump is more likely to cause hemolysis. Cellular damage is related to the plasmatic liberation of markers that largely dominate free hemoglobin and potassium. We reiterate the need for further research and technological investments to guide the development of protocols that promote safe practices and that can contribute to future clinical studies. PMID:27533272

  7. Infusion pumps and red blood cell damage in transfusion therapy: an integrative revision of the academic literature

    Directory of Open Access Journals (Sweden)

    Ana Maria Miranda Martins Wilson

    Full Text Available ABSTRACT Objectives: to obtain information from scientific literature concerning infusion pumps used in administering erythrocyte (red blood cells and to evaluate the implications in the practical use of this equipment by nurses when conducting transfusions. Method: an integrative revision of the following scientific databases: Pubmed/Medline, Scopus, the Virtual Library for Health, SciELO, Web of Science and Cochrane. The following descriptors were used: "infusion pumps", "blood transfusion", "transfused erythrocyte" and "hemolyis". There were no restrictions on the scope of the initial data and it was finalized in December 2014. 17 articles were identified in accordance with the inclusion and exclusion criteria. Results: all of the publications included in the studies were experimental in vitro and covered the use of infusion pumps in transfusion therapy. A summary of the data was presented in a synoptic chart and an analysis of it generated the following categories: cellular damage and the infusion mechanism. Conclusion: infusion pumps can be harmful to erythrocytes based on the infusion mechanism that is used, as the linear peristaltic pump is more likely to cause hemolysis. Cellular damage is related to the plasmatic liberation of markers that largely dominate free hemoglobin and potassium. We reiterate the need for further research and technological investments to guide the development of protocols that promote safe practices and that can contribute to future clinical studies.

  8. Establishing a public umbilical cord blood stem cell bank for South Africa: an enquiry into public acceptability.

    Science.gov (United States)

    Meissner-Roloff, Madelein; Pepper, Michael S

    2013-12-01

    South Africa (SA) faces a large unmet need for bone marrow (BM) transplantation, which could be alleviated in part by establishing a public umbilical cord blood stem cell bank (UCB SCB). Umbilical cord blood is an increasingly utilised source of hematopoietic stem cells for BM transplantation in addition to BM or mobilized peripheral blood stem cells. Establishing a public UCB SCB would therefore be a positive step towards improving the quality of health care in SA by providing for an important unmet need. This study takes the form of an enquiry into the acceptability of establishing a public bank through an interview with and questionnaire completed by mothers-to-be in the antenatal clinic of a large public hospital in SA. Initial results are positive, with 85 % of the participants in favour of establishing a public UCB SCB in SA. This initial probe will serve as a model for a more comprehensive national enquiry into public support and acceptability in different clinics, hospitals and provinces in SA.

  9. Establishing a cell biology platform: isolation and preservation of human blood products

    OpenAIRE

    2014-01-01

    Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina The use of human primary cells provide researchers in different areas with irrefutable more biologically relevant data than using cell lines or animal blood cells. The work was performed in the scope of the Cell Biology Services @ CEDOC, aiming to provide viable and trustful human primary cells and products. We had three main objectives: protocol optimizations for blood cell isolation, culture and cryopre...

  10. Validation of Omron RS8, RS6, and RS3 home blood pressure monitoring devices, in accordance with the European Society of Hypertension International Protocol revision 2010

    Directory of Open Access Journals (Sweden)

    Takahashi H

    2013-05-01

    Full Text Available Hakuo Takahashi, Masamichi Yoshika, Toyohiko YokoiDepartment of Clinical Sciences and Laboratory Medicine, Kansai Medical University, Hirakata, Osaka, JapanBackground: Allowing patients to measure their blood pressure at home is recognized as being of clinical value. However, it is not known how often these measurements are taken correctly. Blood pressure monitors for home use fall into two types based on the position of the cuff, ie, at the upper arm or the wrist. The latter is particularly convenient, as measurements can be taken fully clothed. This study aimed to evaluate the performance of the wrist-type blood pressure monitors Omron RS8 (HEM-6310F-E, Omron RS6 (HEM-6221-E, and Omron RS3 (HEM-6130-E.Methods: A team of three trained doctors validated the performance of these devices by comparing the measurements obtained from these devices with those taken using a standard mercury sphygmomanometer. All the devices met the validation requirements of the European Society of Hypertension International Protocol revision 2010.Results: The difference in blood pressure readings between the tested device and the standard mercury sphygmomanometer was within 3 mmHg, which is acceptable according to the European Society of Hypertension guidelines.Conclusion: All the home devices tested were found to be suitable for measuring blood pressure at home because their performance fulfilled the requirement of the guidelines.Keywords: blood pressure, device, European Society of Hypertension, guideline, measurement, validation

  11. Genetically modified T cells targeting neovasculature efficiently destroy tumor blood vessels, shrink established solid tumors and increase nanoparticle delivery.

    Science.gov (United States)

    Fu, Xinping; Rivera, Armando; Tao, Lihua; Zhang, Xiaoliu

    2013-11-15

    Converting T cells into tumor cell killers by grafting them with a chimeric antigen receptor (CAR) has shown promise as a cancer immunotherapeutic. However, the inability of these cells to actively migrate and extravasate into tumor parenchyma has limited their effectiveness in vivo. Here we report the construction of a CAR containing an echistatin as its targeting moiety (eCAR). As echistatin has high binding affinity to αvβ3 integrin that is highly expressed on the surface of endothelial cells of tumor neovasculature, T cells engrafted with eCAR (T-eCAR) can efficiently lyse human umbilical vein endothelial cells and tumor cells that express αvβ3 integrin when tested in vitro. Systemic administration of T-eCAR led to extensive bleeding in tumor tissues with no evidence of damage to blood vessels in normal tissues. Destruction of tumor blood vessels by T-eCAR significantly inhibited the growth of established bulky tumors. Moreover, when T-eCAR was codelivered with nanoparticles in a strategically designed temporal order, it dramatically increased nanoparticle deposition in tumor tissues, pointing to the possibility that it may be used together with nanocarriers to increase their capability to selectively deliver antineoplastic drugs to tumor tissues.

  12. Perioperative transfusion threshold and ambulation after hip revision surgery

    DEFF Research Database (Denmark)

    Nielsen, Kamilla; Johansson, Pär I; Dahl, Benny;

    2014-01-01

    BACKGROUND: Transfusion with red blood cells (RBC) may be needed during hip revision surgery but the appropriate haemoglobin concentration (Hb) threshold for transfusion has not been well established. We hypothesized that a higher transfusion threshold would improve ambulation after hip revision...... received RBC. CONCLUSIONS: A Hb transfusion threshold of 8.9 g/dL was associated with a statistically significantly faster TUG after hip revision surgery compared to a threshold of 7.3 g/dL but the clinical importance is questionable and the groups did not differ in Hb at the time of testing....

  13. The ant genus Carebara Westwood (Hymenoptera, Formicidae: synonymisation of Pheidologeton Mayr under Carebara, establishment and revision of the C. polita species group

    Directory of Open Access Journals (Sweden)

    Georg Fischer

    2014-09-01

    Full Text Available In this paper the genus Pheidologeton Mayr, 1862 is synonymized under Carebara Westwood, 1840 and the Carebara polita group is established and revised. This species group currently includes six species from the Afrotropical region (C. madibai, C. nicotianae, C. perpusilla, C. polita, C. silvestrii, and C. villiersi and two species from the Neotropical region (C. brevipilosa and C. urichi. The polita group clearly links Carebara and Pheidologeton, and, due to a lack of autapomorphic characters for the latter, a separation of the two genera is no longer justified. As a result Carebara is presented as a monophyletic and better defined genus that can be separated from other genera with more confidence. We present an overview of the distribution and biology of Carebara as well as images from the various genera currently in synonymy under Carebara, and discuss the characters they share. The polymorphism present in Afrotropical and Malagasy Carebara is discussed and one new species from Africa, C. madibai sp. n., is described. The subspecies Carebara perpusilla arnoldiana syn. n., Carebara perpusilla concedens syn. n., and Carebara perpusilla spinosa syn. n. are new synonyms of Carebara perpusilla. Oligomyrmex politus nicotianae is re-elevated to species level and transferred into Carebara, C. nicotianae comb. n., stat. rev.; C. punctata is a new synonym of C. silvestrii comb. n. and C. pygmaea albipes comb. n., syn n., C. pygmaea bugnioni comb. n., syn. n., and C. simularensis syn. n. are new synonyms of C. pygmaea comb. n.. The following names are transferred from Pheidologeton to Carebara as new combinations (with the species epithets adjusted to female endings where necessary: aberrans, affinis, affinis javana, affinis minor, affinis spinosior, affinis sumatrensis, ceylonensis, dentiviris, diversa, diversa draco, diversa ficta, diversa laotina, diversa macgregori, diversa philippina, diversa standfussi, diversa taprobanae, diversa tenuirugosa

  14. Blood

    Science.gov (United States)

    ... Also, blood is either Rh-positive or Rh-negative. So if you have type A blood, it's either A positive or A negative. Which type you are is important if you need a blood transfusion. And your Rh factor could be important ...

  15. Opportunity of objective account of the colorimetric procedure using benzidine indicative at establishing the preliminary presence of blood on the material evidences

    Directory of Open Access Journals (Sweden)

    A. V. Konovalenko

    2015-01-01

    Full Text Available The article presents a modification of the colorimetric method for the preliminary establishment of presence of blood in the stainson the material evidences using benzidine test. The proposed modification is accompanied by photometric accounting and computer processing of the results. Performance, objectivity, as well as other features and advantages of this method when used in forensic practice are described in detail.

  16. HMSRP Hawaiian Monk Seal Blood Values (Establishing hematology and serum chemistry reference ranges for wild Hawaiian Monk Seals)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hematology and serum chemistry evaluations are essential to a patients comprehensive health exam by providing measures of organ function, blood cell volume and...

  17. Distribution of blood derivatives by registered blood establishments that qualify as health care entities; Prescription Drug Marketing Act of 1987; Prescription Drug Amendments of 1992; delay of applicability date. Final rule; delay of applicability date.

    Science.gov (United States)

    2006-11-13

    The Food and Drug Administration (FDA) is further delaying, until December 1, 2008, the applicability date of a certain requirement of a final rule published in the Federal Register of December 3, 1999 (64 FR 67720) (the final rule). The final rule implements the Prescription Drug Marketing Act of 1987 (PDMA), as modified by the Prescription Drug Amendments of 1992 (PDA), and the Food and Drug Administration Modernization Act of 1997 (the Modernization Act). The provisions of the final rule became effective on December 4, 2000, except for certain provisions whose effective or applicability dates were delayed in five subsequent Federal Register notices, until December 1, 2006. The provision with the delayed applicability date would prohibit wholesale distribution of blood derivatives by registered blood establishments that meet the definition of a "health care entity." In the Federal Register of February 1, 2006 (71 FR 5200), FDA published a proposed rule specific to the distribution of blood derivatives by registered blood establishments that qualify as health care entities (the proposed rule). The proposed rule would amend certain limited provisions of the final rule to allow certain registered blood establishments that qualify as health care entities to distribute blood derivatives. In response to the proposed rule, FDA received substantive comments. As explained in the SUPPLEMENTARY INFORMATION section of this document, further delaying the applicability of Sec. 203.3(q) (21 CFR 203.3(q)) to the wholesale distribution of blood derivatives by health care entities is necessary to give the agency additional time to address comments on the proposed rule, consider whether regulatory changes are appropriate, and, if so, to initiate such changes.

  18. Establishment of a real-time PCR for quantifying transforming growth factor beta1 in blood of hepatocellular carcinoma patients

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Background: The carcinogenesis of hepatocellular carcinoma (HCC) is a multi-factorial, multistep and complex process. Its prognosis is poor and early detection is of the utmost importance. Transforming growth factor β1 (TGF-β1) message RNA (mRNA) has been reported to be elevated in HCC patients using Northern blotting. However, little work has been done about the detection of TGF-β1 mRNA levels in peripheral blood of patients with HCC using the real-time polymerase chain reactions (PCR) method. Objective: To assess the prognostic value of quantitative levels of TGF-β1 mRNA in peripheral blood of patients with HCC, and to investigate the relationship between the expression of TGF-β1 mRNA in peripheral blood and many diagnostic and pathological factors. Methods: We developed an optimized Taqman real-time PCR to quantify TGF-β1 mRNA in peripheral blood of 53 patients with HCC and 44 healthy volunteers. In addition, blood was collected from patients with HCC for measuring levels of total bilirubin (TBil), prealbumin, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyltranspeptidase (GGT), alpha-L-fucosidase (AFU), alpha fetoprotein (AFP), carcino-embryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), viral load and platelet counts. Statistical analysis was performed using the SPSS software system (SPSS 10.0). Results: In real-time PCR, fluorescence was detectable in all blood specimens from patients with HCC and healthy volunteers. The levels of TGF-β1 mRNA expression in patients with HCC were significantly higher compared to that in healthy volunteers (P<0.000 1), suggesting an association of the activated TGF-β1 gene transcription with hepatocarcinogenesis. Patients with HCC were divided into 2 groups according to their TGF-β1 mRNA above (group A, n=28) or below (group B, n=25) the mean level. Statistical results demonstrated that TGF-β1 mRNA expression level was correlated with patients age, serum levels of CEA

  19. Establishing baseline levels of trace elements in blood and skin of bottlenose dolphins in Sarasota Bay, Florida: Implications for non-invasive monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Bryan, Colleen E. [National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Fort Johnson Road, Charleston, South Carolina 29412 (United States); College of Charleston, Grice Marine Laboratory, 205 Fort Johnson Road, Charleston, South Carolina 29412 (United States)], E-mail: colleen.bryan@nist.gov; Christopher, Steven J. [National Institute of Standards and Technology, Hollings Marine Laboratory, 331 Fort Johnson Road, Charleston, South Carolina 29412 (United States); Balmer, Brian C.; Wells, Randall S. [Chicago Zoological Society c/o Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, Florida 34236 (United States)

    2007-12-15

    Several major unusual mortality events occurring in recent years have increased the level of concern for the health of bottlenose dolphin populations along the United States Atlantic and Gulf of Mexico coasts. Trace element concentrations were examined in a population of free-ranging dolphins in Sarasota Bay, Florida, in order to develop a benchmark for future comparisons within and between populations. Whole blood (n = 51) and skin (n = 40) samples were collected through capture and release health assessment events during 2002-2004. Samples were analyzed for Al, V, Cr, Mn, Cu, Zn, As, Se, Rb, Sr, Mo, Cd, and Pb by inductively coupled plasma mass spectrometry (ICPMS) and Hg via atomic fluorescence spectrometry (AFS). Trace element concentrations (wet mass) in skin were 2 to 45 times greater than blood, except Cu was approximately 1.5 times higher in blood. Statistically strong correlations (p < 0.05) were found for V, As, Se, Rb, Sr, and Hg between blood and skin demonstrating that these tissues can be used as effective non-lethal monitoring tools. The strongest correlation was established for Hg (r = 0.9689) and concentrations in both blood and skin were above the threshold at which detrimental effects are observed in other vertebrate species. Female dolphins had significantly greater Hg concentrations in blood and skin and Pb concentrations in skin, relative to males. Calves exhibited significantly lower V, As, and Hg concentrations in blood and V and Hg concentrations in skin, relative to other age classes. Rubidium and Cu concentrations in skin were greatest in subadults and calves, respectively. In blood, V, Zn, and As concentrations were significantly greater in winter, relative to summer, and the opposite trend was observed for Rb and Sr concentrations. In skin, Cu and Zn concentrations were significantly greater in winter, relative to summer, and the opposite trend was observed for Mn, Rb, Cd, and Pb concentrations. The baseline concentrations and trends

  20. Establishing the Validity and Reliability of the Student Practice Evaluation Form-Revised (SPEF-R) in Occupational Therapy Practice Education: A Rasch Analysis.

    Science.gov (United States)

    Rodger, Sylvia; Chien, Chi-Wen; Turpin, Merrill; Copley, Jodie; Coleman, Allison; Brown, Ted; Caine, Anne-Maree

    2016-03-01

    This study investigated construct validity and internal consistency of the Student Practice Evaluation Form-Revised Edition Package (SPEF-R) which evaluates students' performance on practice education placements. The SPEF-R has 38 items covering eight domains, and each item is rated on a 5-point rating scale. Data from 125 students' final placement evaluations in their final year study were analyzed using the Rasch measurement model. The SPEF-R exhibited satisfactory rating scale performance and unidimensionality across the eight domains, providing construct validity evidence. Only 2 items misfit Rasch model's expectations (both related to students' performance with client groups, which were often rated as not observed). Additionally, the internal consistency of each SPEF-R domain was found to be excellent (Cronbach's α = .86 to .91) and all individual items had reasonable to excellent item-total correlation coefficients. The study results indicate that the SPEF-R can be used with confidence to evaluate students' performance during placements, but continued validation and refinement are required.

  1. In Vitro Blood-Brain Barrier Models-An Overview of Established Models and New Microfluidic Approaches

    DEFF Research Database (Denmark)

    Wolff, Anette; Antfolk, Maria; Brodin, Birger;

    2015-01-01

    The societal need for new central nervous system (CNS) medicines is substantial, because of the global increase in life expectancy and the accompanying increase in age-related CNS diseases. Low blood-brain barrier (BBB) permeability has been one of the major causes of failure for new CNS drug...... candidates. There has therefore been a great interest in cell models, which mimic BBB permeation properties. In this review, we present an overview of the performance of monocultured, cocultured, and triple-cultured primary cells and immortalized cell lines, including key parameters such as transendothelial......-of-the-art models and it was noted that, although they show great promise, these systems have not yet reached beyond the proof-of-concept stage. In general, it was found that there were large variations in experimental protocols, BBB phenotype markers, and paracellular flux markers used. It is the author's opinion...

  2. Revised Rules for Concrete Bridges

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle; Jensen, F. M.; Middleton, C.;

    This paper is based on research performed for the Highway Agency, London, UK under the project DPU/9/44 "Revision of Bridge Assessment Rules Based on Whole Life Performance: Concrete Bridges" It contains details of a methodology which can be used to generate Whole Life (WL) reliability profiles....... These WL reliability profiles may be used to establish revised rules for Concrete Bridges....

  3. Establishment of the model of white blood cell membrane chromatography and screening of antagonizing TLR4 receptor component from Atractylodes macrocephala Koidz

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A model of white blood cell membrane chromatography (WB-CMC) was established to screen active component from Atractylodes macrocephala Koidz. The component can antagonize Toll-like receptor 4 (TLR4) and inhibit inflammatory reaction. In the model of WB-CMC, cell membrane stationary phase (CMSP) was prepared by immobilizing the rabbit white blood cell membrane (WBCM) onto the surface of silica carrier and taxinol was used as a model molecule. The active component which can act on WBCM and its receptor (such as TLR4) as an effective target in A. macrocephala was determined by using a replacement experiment. The anti-inflammatory effects of the active component were tested by using pharmacological methods in vivo. The results indicated that the retention characteristics of atractylenolide I as active component was similar to that of taxinol in the model of WB-CMC. And so, atractylenolide I acted on the WBCM and TLR4 and its anti-inflammatory activity was related with antagonizing TLR4. Therefore, the interaction between the active component and WBCM and its receptor can be simulated by the model of WB-CMC in vitro. This model can be used to screen active components and to study effective characteristics for acting on definite targets.

  4. FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection

    Directory of Open Access Journals (Sweden)

    Murphy Brian

    2012-02-01

    Full Text Available Abstract Background Feline immunodeficiency virus (FIV is a lentivirus of cats that establishes a lifelong persistent infection with immunologic impairment. Results In an approximately 2 year-long experimental infection study, cats infected with a biological isolate of FIV clade C demonstrated undetectable plasma viral loads from 10 months post-infection onward. Viral DNA was detected in CD4+CD25+ and CD4+CD25- T cells isolated from infected cats whereas viral RNA was not detected at multiple time points during the early chronic phase of infection. Viral transcription could be reactivated in latently infected CD4+ T cells ex vivo as demonstrated by detectable FIV gag RNA and 2-long terminal repeat (LTR circle junctions. Viral LTR and gag sequences amplified from peripheral blood mononuclear cells during early and chronic stages of infection demonstrated minimal to no viral sequence variation. Conclusions Collectively, these findings are consistent with FIV latency in peripheral blood CD4+ T cells isolated from chronically infected cats. The ability to isolate latently FIV-infected CD4+ T lymphocytes from FIV-infected cats provides a platform for the study of in vivo mechanisms of lentiviral latency.

  5. Revising Translations

    DEFF Research Database (Denmark)

    Rasmussen, Kirsten Wølch; Schjoldager, Anne

    2011-01-01

    out by specialised revisers, but by staff translators, who revise the work of colleagues and freelancers on an ad hoc basis. Corrections are mostly given in a peer-to-peer fashion, though the work of freelancers and inexperienced in-house translators is often revised in an authoritative (nonnegotiable......) way. Most respondents and interviewees are worried about increasing pressures on the translation market, which, combined with customers’ general lack of understanding of the translation process, mean that systematic, all-encompassing quality assurance is rarely financially viable....

  6. Revision Notes

    CERN Document Server

    Matthewson, Siobhan; Debbadi, Margaret

    2012-01-01

    Revision Notes: CCEA ICT for GCSE has been written by experienced teachers and examiners so that you can be confident that it covers only the facts and ideas you will be expected to recall and use in the exam. - Essential facts are carefully organised to make revising easier. - Exams tips show you how to avoid losing marks and get the best grade. - Check your understanding questions support you in the run-up to the exams, with answers provided free online at www.hodderplus.co.uk. This book will help you plan and pace your revision to suit your learning needs and can be integrated with other re

  7. Scar revision

    Science.gov (United States)

    ... chap 21. Lorenz P, Bari AS. Scar prevention, treatment, and revision. In: Neligan PC, ed. Plastic Surgery . 3rd ed. Philadelphia, PA: Elsevier; 2013:chap 16. Read More Contracture deformity Keloids Review Date 4/14/2015 Updated ...

  8. Ethical Revision.

    Science.gov (United States)

    Jackman, Mary Kathryn

    1994-01-01

    Discusses the dilemma of how to respond to student papers advancing morally repugnant positions. Advocates conceptualizing writing as an ethical act and connecting ethics and revision. Describes briefly how three such student papers were handled. (SR)

  9. A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.

    Directory of Open Access Journals (Sweden)

    Christian Freese

    Full Text Available In the pathogenesis of Alzheimer's disease (AD the homeostasis of amyloid precursor protein (APP processing in the brain is impaired. The expression of the competing proteases ADAM10 (a disintegrin and metalloproteinase 10 and BACE-1 (beta site APP cleaving enzyme 1 is shifted in favor of the A-beta generating enzyme BACE-1. Acitretin--a synthetic retinoid-e.g., has been shown to increase ADAM10 gene expression, resulting in a decreased level of A-beta peptides within the brain of AD model mice and thus is of possible value for AD therapy. A striking challenge in evaluating novel therapeutically applicable drugs is the analysis of their potential to overcome the blood-brain barrier (BBB for central nervous system targeting. In this study, we established a novel cell-based bio-assay model to test ADAM10-inducing drugs for their ability to cross the BBB. We therefore used primary porcine brain endothelial cells (PBECs and human neuroblastoma cells (SH-SY5Y transfected with an ADAM10-promoter luciferase reporter vector in an indirect co-culture system. Acitretin served as a model substance that crosses the BBB and induces ADAM10 expression. We ensured that ADAM10-dependent constitutive APP metabolism in the neuronal cells was unaffected under co-cultivation conditions. Barrier properties established by PBECs were augmented by co-cultivation with SH-SY5Y cells and they remained stable during the treatment with acitretin as demonstrated by electrical resistance measurement and permeability-coefficient determination. As a consequence of transcellular acitretin transport measured by HPLC, the activity of the ADAM10-promoter reporter gene was significantly increased in co-cultured neuronal cells as compared to vehicle-treated controls. In the present study, we provide a new bio-assay system relevant for the study of drug targeting of AD. This bio-assay can easily be adapted to analyze other Alzheimer- or CNS disease-relevant targets in neuronal cells

  10. A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug.

    Science.gov (United States)

    Freese, Christian; Reinhardt, Sven; Hefner, Gudrun; Unger, Ronald E; Kirkpatrick, C James; Endres, Kristina

    2014-01-01

    In the pathogenesis of Alzheimer's disease (AD) the homeostasis of amyloid precursor protein (APP) processing in the brain is impaired. The expression of the competing proteases ADAM10 (a disintegrin and metalloproteinase 10) and BACE-1 (beta site APP cleaving enzyme 1) is shifted in favor of the A-beta generating enzyme BACE-1. Acitretin--a synthetic retinoid-e.g., has been shown to increase ADAM10 gene expression, resulting in a decreased level of A-beta peptides within the brain of AD model mice and thus is of possible value for AD therapy. A striking challenge in evaluating novel therapeutically applicable drugs is the analysis of their potential to overcome the blood-brain barrier (BBB) for central nervous system targeting. In this study, we established a novel cell-based bio-assay model to test ADAM10-inducing drugs for their ability to cross the BBB. We therefore used primary porcine brain endothelial cells (PBECs) and human neuroblastoma cells (SH-SY5Y) transfected with an ADAM10-promoter luciferase reporter vector in an indirect co-culture system. Acitretin served as a model substance that crosses the BBB and induces ADAM10 expression. We ensured that ADAM10-dependent constitutive APP metabolism in the neuronal cells was unaffected under co-cultivation conditions. Barrier properties established by PBECs were augmented by co-cultivation with SH-SY5Y cells and they remained stable during the treatment with acitretin as demonstrated by electrical resistance measurement and permeability-coefficient determination. As a consequence of transcellular acitretin transport measured by HPLC, the activity of the ADAM10-promoter reporter gene was significantly increased in co-cultured neuronal cells as compared to vehicle-treated controls. In the present study, we provide a new bio-assay system relevant for the study of drug targeting of AD. This bio-assay can easily be adapted to analyze other Alzheimer- or CNS disease-relevant targets in neuronal cells, as their

  11. Significance of Establishment of Cord Blood Bank and Its Information Networking Management on Cord Blood Stem Cell Transplantation%脐带血库的建立及其信息网络化管理对脐带血干细胞移植的意义

    Institute of Scientific and Technical Information of China (English)

    刘婷

    2011-01-01

    目的:探讨如何建立脐带血(UCB)库、UCB库信息网络化管理策略及对UCB干细胞移植的意义.方法:通过建立UCB库及UCB库的信息网络化管理,使UCB库在UCB干细胞移植中发挥尽可能大的作用.结果:建立起来的血库切实可行,UCB库信息网络化管理最大限度地发挥了UCB在UCB干细胞移植中的作用.结论:UCB库的建立及其信息网络化管理对UCB干细胞移植意义重大,可最大限度地发挥UCB库的作用.%[ Objective ] To explore how to establish a cord blood bank, information networking management strategies of cord blood bank and its significance on cord blood stem cell transplantation. [ Methods ] In order to make the cord blood bank plays its full role in cord blood stem cell transplantation, the cord blood bank was established and the information networking management was carried out. [ Results]The blood bank is feasible, and umbilical cord blood gets the maximum use in cord blood stem cell transplantation by implementation of information networking management of cord blood bank. [ Conclusion] The establishment of cord blood bank and its information networking management has a great significance on cord blood stem cell transplantation, which can get a maximum effect of cord blood bank.

  12. Requirements for blood and blood components intended for transfusion or for further manufacturing use. Final rule.

    Science.gov (United States)

    2015-05-22

    The Food and Drug Administration (FDA) is amending the regulations applicable to blood and blood components, including Source Plasma, to make the donor eligibility and testing requirements more consistent with current practices in the blood industry, to more closely align the regulations with current FDA recommendations, and to provide flexibility to accommodate advancing technology. In order to better assure the safety of the nation's blood supply and to help protect donor health, FDA is revising the requirements for blood establishments to test donors for infectious disease, and to determine that donors are eligible to donate and that donations are suitable for transfusion or further manufacture. FDA is also requiring establishments to evaluate donors for factors that may adversely affect the safety, purity, and potency of blood and blood components or the health of a donor during the donation process. Accordingly, these regulations establish requirements for donor education, donor history, and donor testing. These regulations also implement a flexible framework to help both FDA and industry to more effectively respond to new or emerging infectious agents that may affect blood product safety.

  13. Admissible and Restrained Revision

    CERN Document Server

    Booth, R; 10.1613/jair.1874

    2011-01-01

    As partial justification of their framework for iterated belief revision Darwiche and Pearl convincingly argued against Boutiliers natural revision and provided a prototypical revision operator that fits into their scheme. We show that the Darwiche-Pearl arguments lead naturally to the acceptance of a smaller class of operators which we refer to as admissible. Admissible revision ensures that the penultimate input is not ignored completely, thereby eliminating natural revision, but includes the Darwiche-Pearl operator, Nayaks lexicographic revision operator, and a newly introduced operator called restrained revision. We demonstrate that restrained revision is the most conservative of admissible revision operators, effecting as few changes as possible, while lexicographic revision is the least conservative, and point out that restrained revision can also be viewed as a composite operator, consisting of natural revision preceded by an application of a "backwards revision" operator previously studied by Papini. ...

  14. ACL Revision

    Science.gov (United States)

    Costa-Paz, Matias; Dubois, Julieta Puig; Zicaro, Juan Pablo; Rasumoff, Alejandro; Yacuzzi, Carlos

    2017-01-01

    Objectives: The purpose of this study was to evaluate a series of patients one year after an ACL revision with clinical evaluation and MRI, to consider their condition before returning to sports activities. Methods: A descriptive, prospective and longitudinal study was performed. A series of patients who underwent an ACL revision between March 2014 and March 2015 were evaluated after one year post surgery. They were evaluated using the Lysholm score, IKDC, Tegner, artrometry and MRI (3.0 t). A signal pattern and osteointegration was determined in the MRI. Graft signal intensity of the ACL graft using the signal/noise quotient value (SNQ) was also determined to evaluate the ligamentatization process state. Results: A total of 18 male patients were evaluated with a mean age of 31 years old.Average scores were: Lysholm 88 points, IKDC 80 points, Pre-surgical Tegner 9 points and postoperative 4 points. Artrhometry (KT1000) at 20 newtons showed a side to side difference of less than 3 mm in 88%. Only 44% of patients returned to their previous sport activity one year after revision.The MRI showed a heterogeneous signal in neoligaments in 34% of patients. SNQ showed graft integration in only 28%. Synovial fluid was found in bone-graft interphase in 44% of tunnels, inferring partial osteointegration. The heterogeneous signal was present in 50% of patients who did not return to the previous sport level activity. (Fisher statistics: p = 0.043) There were no meaningful differences in patients with auto or allografts. Conclusion: Although the clinical evaluation was satisfactory, only 44% of patients returned to the previous level of sport activity one year after the ACL surgery. The ligamentatization process was found in 28% of knees evaluated with MRI one year later. Partial osteointegration is inferred in 44%. Results showed a meaningful relation between the signal of neoligaments in the MRI and the return to sport activity in said series of patients. MRI is a useful tool

  15. To Establish Bank of Rare Blood Type to Protect Blood Demand for Clinical Use%建立稀有血型库保障临床用血需求

    Institute of Scientific and Technical Information of China (English)

    杨青成

    2011-01-01

    The paper proposed several practice suggestions: taking suspension red blood cell bank as emergency use, taking frozen red blood cells bank as main usage, and taking floating blood donors bank as supplement, which was an effective method to protect the timely, adequate and safe supply of rare blood type.%总结了建立以悬浮红细胞库为应急、以冰冻红细胞库为主力、以流动献血者库为补充的稀有血型库的实践,认为此举是保障稀有血型血液的及时、足量、安全供应的有效方法.

  16. Guidance document for revision of DOE Order 5820.2A, Radioactive Waste Technical Support Program. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Kudera, D.E.; McMurtrey, C.D.; Meagher, B.G.

    1993-04-01

    This document provides guidance for the revision of DOE Order 5820.2A, ``Radioactive Waste Management.`` Technical Working Groups have been established and are responsible for writing the revised order. The Technical Working Groups will use this document as a reference for polices and procedures that have been established for the revision process. The overall intent of this guidance is to outline how the order will be revised and how the revision process will be managed. In addition, this document outlines technical issues considered for inclusion by a Department of Energy Steering Committee.

  17. Blood Types

    Science.gov (United States)

    ... maternity. Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells Platelets Plasma ... About Blood Blood Facts and Statistics Blood Types Blood Components What Happens to Donated Blood Blood and Diversity ...

  18. Distribution of certain drug products by registered blood establishments and comprehensive hemophilia diagnostic treatment centers that qualify as health care entities; Prescription Drug Marketing Act of 1987; Prescription Drug Amendments of 1992; policies, requirements and administrative procedures. Final rule.

    Science.gov (United States)

    2008-10-09

    The Food and Drug Administration (FDA) is amending its regulations to allow certain registered blood establishments and comprehensive hemophilia diagnostic treatment centers that are also health care entities to distribute certain drug products. The final rule amends limited provisions of the regulations implementing the Prescription Drug Marketing Act of 1987 (PDMA), as modified by the Prescription Drug Amendments of 1992 (PDA). These regulations, among other things, restrict the sale, purchase, or trade of, or the offer to sell, purchase, or trade, prescription drugs purchased by hospitals and other health care entities.

  19. Establishment of loop-mediated isothermal amplification (LAMP) for rapid detection of Brucella spp. and application to milk and blood samples.

    Science.gov (United States)

    Song, Liuyan; Li, Juntao; Hou, Shuiping; Li, Xunde; Chen, Shouyi

    2012-09-01

    Brucella spp. are facultative intracellular bacteria that infect humans and animals. In this study, the loop-mediated isothermal amplification (LAMP) was used to detect the Brucella-specific gene omp25. Reaction conditions were optimized as temperature 65°C, reaction time 60 min, Mg(2+) concentration 8.0 mmol/L, polymerase content Bst DNA, 0.5 μL, deoxyribonucleotide concentration 1.6 mmol/L, and inner/outer primer ratio 1:8. The LAMP method was evaluated with 4 Brucella species and 29 non-Brucella bacteria species. Positive reactions were observed on all the 4 Brucella species but not on any non-Brucella species. The limit of detection of the LAMP method was 3.81 CFU Brucella spp. Using the LAMP method, 7 of 110 raw milk samples and 5 of 59 sheep blood samples were detected positive of Brucella spp. Results indicated that LAMP is a fast, specific, sensitive, inexpensive, and suitable method for diagnosis of Brucella spp. infection.

  20. Establishing and evaluating bar-code technology in blood sampling system: a model based on human centered human-centered design method.

    Science.gov (United States)

    Chou, Shin-Shang; Yan, Hsiu-Fang; Huang, Hsiu-Ya; Tseng, Kuan-Jui; Kuo, Shu-Chen

    2012-01-01

    This study intended to use a human-centered design study method to develop a bar-code technology in blood sampling process. By using the multilevel analysis to gather the information, the bar-code technology has been constructed to identify the patient's identification, simplify the work process, and prevent medical error rates. A Technology Acceptance Model questionnaire was developed to assess the effectiveness of system and the data of patient's identification and sample errors were collected daily. The average scores of 8 items users' perceived ease of use was 25.21(3.72), 9 items users' perceived usefulness was 28.53(5.00), and 14 items task-technology fit was 52.24(7.09), the rate of patient identification error and samples with order cancelled were down to zero, however, new errors were generated after the new system deployed; which were the position of barcode stickers on the sample tubes. Overall, more than half of nurses (62.5%) were willing to use the new system.

  1. Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes.

    Directory of Open Access Journals (Sweden)

    Bryan S Briney

    Full Text Available A number of antibodies that efficiently neutralize microbial targets contain long heavy chain complementarity determining region 3 (HCDR3 loops. For HIV, several of the most broad and potently neutralizing antibodies have exceptionally long HCDR3s. Two broad potently neutralizing HIV-specific antibodies, PG9 and PG16, exhibit secondary structure. Two other long HCDR3 antibodies, 2F5 and 4E10, protect against mucosal challenge with SHIV. Induction of such long HCDR3 antibodies may be critical to the design of an effective vaccine strategy for HIV and other pathogens, however it is unclear at present how to induce such antibodies. Here, we present genetic evidence that human peripheral blood antibodies containing long HCDR3s are not primarily generated by insertions introduced during the somatic hypermutation process. Instead, they are typically formed by processes occurring as part of the original recombination event. Thus, the response of B cells encoding antibodies with long HCDR3s results from selection of unusual clones from the naïve repertoire rather than through accumulation of insertions. These antibodies typically use a small subset of D and J gene segments that are particularly suited to encoding long HCDR3s, resulting in the incorporation of highly conserved genetic elements in the majority of antibody sequences encoding long HCDR3s.

  2. 3种不同血瘀证动物模型的建立与评价%The establishment and evaluation of three different kinds of animal model of blood stasis syndrome

    Institute of Scientific and Technical Information of China (English)

    梁耀月; 李佳佳; 董世芬; 张荣; 袁悦莹; 孙建宁

    2016-01-01

    目的:建立痰浊血瘀、气滞血瘀、痰浊+气滞血瘀大鼠模型,研究不同血瘀状态动物模型的特征。方法选用SD大鼠,随机分为正常对照组、高脂饲料组、慢性刺激组( chro-nic unpredictable mild stress,CUMS)、高脂饲料+慢性刺激组,分别采用相应因素干预6周。于2、4、6周动态监测动物体重、旷场行为、血脂和血清皮质酮指标;实验终点(6周)采用小动物超声和左心室插管法检测心功能,采用黏度仪、红细胞变形/聚集测试仪检测血液流变性相关指标。结果与正常对照组大鼠相比,采用高脂饲料、慢性不可预知性刺激后均可引起血瘀状态,对动物的行为学、血脂、心脏功能、血液黏度造成了不同程度的影响,当两因素叠加时,血瘀相关指标变化最明显,表现为:与正常对照组比较,体重明显降低(P<0.01),2周时水平运动、垂直运动、运动时间均减少(P<0.01或 P <0.05),2周、4周时,血清皮质酮上升( P <0.01或P<0.05),4周、6周时TG明显上升(P<0.01)。6周时,血流速度减慢(P<0.01),收缩末期左室前壁、后壁厚度均增厚(P<0.01或P<0.05),舒张期左心室指数上升(P<0.01),左心室最大收缩速率降低(P<0.05),全血黏度上升(P<0.01)。结论高脂饲料喂养和慢性不可预知性刺激均可形成血瘀状态,但是具有不同的特点。当两因素叠加时,动物可明显出现行为学、血液黏度、心脏功能、血脂等指标的异常,可为血瘀证以及相关药物的研究提供依据。%Aim To establish phlegm and blood stasis, qi-stag-nation and blood stasis, phlegm turbid+qi-stagnation and blood stasis model in rats and to study the characteristics of animal models with different blood stasis. Methods SD rats were ran-domly divided into normal group, high fat diet group, chronic unpredictable mild stress group ( CUMS ) and high fat diet +chronic unpredictable mild stress group. Different states

  3. Cord Blood

    Directory of Open Access Journals (Sweden)

    Saeed Abroun

    2014-05-01

    Full Text Available   Stem cells are naïve or master cells. This means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. Stem cells are found in many parts of the human body, although some sources have richer concentrations than others. Some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and human embryos, which last one are controversial and their use can be illegal in some countries. Cord blood is a sample of blood taken from a newborn baby's umbilical cord. It is a rich source of stem cells, umbilical cord blood and tissue are collected from material that normally has no use following a child’s birth. Umbilical cord blood and tissue cells are rich sources of stem cells, which have been used in the treatment of over 80 diseases including leukemia, lymphoma and anemia as bone marrow stem cell potency.  The most common disease category has been leukemia. The next largest group is inherited diseases. Patients with lymphoma, myelodysplasia and severe aplastic anemia have also been successfully transplanted with cord blood. Cord blood is obtained by syringing out the placenta through the umbilical cord at the time of childbirth, after the cord has been detached from the newborn. Collecting stem cells from umbilical blood and tissue is ethical, pain-free, safe and simple. When they are needed to treat your child later in life, there will be no rejection or incompatibility issues, as the procedure will be using their own cells. In contrast, stem cells from donors do have these potential problems. By consider about cord blood potency, cord blood banks (familial or public were established. In IRAN, four cord blood banks has activity, Shariati BMT center cord blood bank, Royan familial cord blood banks, Royan public cord blood banks and Iranian Blood Transfusion Organ cord blood banks. Despite 50,000 sample which storage in these banks, but the

  4. ACL-TOP700血凝仪凝血4项正常参考区间的建立%Establishment of normal reference interval for four items of blood coagulation on ACL-TOP Automatic coagulation analyzer

    Institute of Scientific and Technical Information of China (English)

    陈锐; 鲁燕飞; 周志兰; 姚振国; 陈国强

    2015-01-01

    Objective To establish normal reference interval for four items of blood coagulation on ACL‐TOP Automatic coagu‐lation analyzer .Methods The fasting anti‐coagulation blood samples were collected from 1 268 inpatients and people conducted physical examination ,all subjects without liver disease ,history of blood disease and coagulation disfunction .The prothrombin time (PT) ,activated partical prothrombin time(APTT) ,thrombin time(TT) and serum levels of fibrinogen(FIB) were determined by u‐sing ACL‐TOP automatic coagulation analyzer which was producted by America IL company .And data of determination results were used to establish the normal reference intervals of indexes in this laboratory .Results The precision and accuracy of this analy‐zer was good .There were differences of normal reference intervals between which established in this laboratory and which provided by the manufacturer .Conclusion Each laboratory should establish its own normal reference interval ,not blindly refer to reference interval provided by regents manual .%目的:建立ACL‐TOP700全自动血凝分析仪本实验室凝血4项的正常参考区间。方法筛选1268住院患者及门诊体检者,均无肝病、血液病史及出凝血功能障碍,空腹采集其静脉抗凝血。采用美国IL公司生产的ACL‐TOP700全自动血凝分析仪进行凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)测定,建立本实验室 PT、APTT、TT、FIB的正常参考区间。结果该仪器精密度、正确度均良好,各参考区间与厂家提供的参考区间有一定的差异。结论各个实验室应建立自己的参考区间,不可盲目引用厂家试剂说明书上提供的正常参考区间。

  5. Loosening After Acetabular Revision

    DEFF Research Database (Denmark)

    Beckmann, Nicholas A.; Weiss, Stefan; Klotz, Matthias C.M.;

    2014-01-01

    The best method of revision acetabular arthroplasty remains unclear. Consequently, we reviewed the literature on the treatment of revision acetabular arthroplasty using revision rings (1541 cases; mean follow-up (FU) 5.7 years) and Trabecular Metal, or TM, implants (1959 cases; mean FU 3.7 years)...

  6. Establishment and application of viral inactivation/removal technology for blood products%血液制品病毒灭活/去除技术平台的建立与应用

    Institute of Scientific and Technical Information of China (English)

    尹惠琼; 王蕊; 朱凤宣; 王建国; 章金刚

    2015-01-01

    Objective To establish viral inactivation/removal techniques for blood products , and apply them to inacti-vation/removal process validation of blood products .Methods Enveloped and non-enveloped model viruses were propaga-ted.Viral inactivation/removal techniques for blood products ,including solvent/detergent (S/D) treatment, low pH incuba-tion, dry heat method, pasteurization,and nanofiltration, were established.The virus titer was evaluated using cytopathic effects ( CPE) and Spearman and Karber method .The viral inactivation/removal techniques were believed to be effective when LRV≥4.These techniques were used in viral inactivation /removal validation of blood products .Results Enveloped model viruses were inactivated through S/D treatment and the low pH incubation method .Enveloped and non-enveloped model viruses were inactivated through dry heat and pasteurization .Within a certain range of filtration capacity , PPV was removed through nanofiltration .Conclusion The established viral inactivation/removal techniques can be used in viral inactivation/removal process validation of blood products , which can improve viral safety of blood products .%目的:建立血液制品病毒灭活/去除技术并应用于血液制品的病毒灭活/去除工艺验证。方法建立指示病毒库以及S/D处理法、低pH孵放法、干热法、巴氏消毒法、纳米膜过滤法等血液制品病毒灭活/去除技术,采用细胞病变法测定病毒滴度,Spearman和Karber法计算病毒滴度,病毒滴度降低量( LRV)≥4判为有效,对企业的血液制品样品进行病毒灭活/去除验证。结果 S/D处理法和低pH孵放法可有效灭活有包膜指示病毒,干热法和巴氏消毒法可有效灭活有、无包膜指示病毒,纳米膜过滤法可在一定过滤量范围内去除PPV指示病毒。结论所建立的血液制品病毒灭活/去除技术可用于血液制品的病毒灭活/去除工艺验证,以提高血液制品的病毒安全性。

  7. Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order with ROTC 1, Revision No. 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    2008-02-01

    Many Federal Facility Agreement and Consent Order (FFACO) Use Restrictions (URs) have been established at various corrective action sites (CASs) as part of FFACO corrective actions (FFACO, 1996; as amended January 2007). Since the signing of the FFACO in 1996, practices and procedures relating to the implementation of risk-based corrective action (RBCA) have evolved. This document is part of an effort to re-evaluate all FFACO URs against the current RBCA criteria (referred to in this document as the Industrial Sites [IS] RBCA process) as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006c). Based on this evaluation, the URs were sorted into the following categories: 1. Where sufficient information exists to determine that the current UR is consistent with the RCBA criteria 2. Where sufficient information exists to determine that the current UR may be removed or downgraded based on RCBA criteria. 3. Where sufficient information does not exist to evaluate the current UR against the RCBA criteria. After reviewing all the existing FFACO URs, the 49 URs addressed in this document have sufficient information to determine that these current URs may be removed or downgraded based on RCBA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RCBA criteria.

  8. The establishment and application of dynamic model of red blood cell suspension's electrolyte changing%红细胞悬浮液电解质动态变化模型的建立及其初步应用

    Institute of Scientific and Technical Information of China (English)

    廖小凤; 谭均强; 高炳谏; 区勇勤

    2013-01-01

    Objective To establish the dynamic model of red blood cell suspension's electrolyte changing of during the storage time. Methods The samples were collected from red blood cell suspensions after it had been preserved 3 days,5 days,7 days,14 days,21 days,28 days,35 days,and 10 samples were collected at each point time,and them testing K+ ,Na+,Cl- ,and analysing the results. Results The concentration of Na+ decreased and then increased in the early stage,but it always been lower than the initial concentration . The concentration of Cl-changed less in the preservation period,which were not significant statistically difference. The concentration of K+had been beyond the scope of normai reference values(3.5~5.5 mmol/mL),as the red blood cell suspension were preserved on 3 days,and K+ increased with the preservation time,but it's rate of rise were differed in different periods. Conclusion To establishe the dynamic model of red blood cell suspension's electrolyte changing are favorable to control blood inventory,and transfusing the red blood stored in 21days are beneficial for reducing the patient's potassium load .%目的研究建立红细胞悬浮液在保存期内电解质动态变化模型。方法在红细胞保存的24h、3d、5d、7d、14 d、21 d、28 d、35 d等8个时间点,分别采样10份,进行K+、Na+、Cl-测定,并对结果进行统计学分析。结果在保存初期内,Na+浓度先下降后上升,但始终比保存初期的Na+浓度要偏低;Cl-浓度在整个保存期内的变化差异无统计学意义;至保存期的第5天,红细胞悬液的K+浓度已经超出正常人参考值范围(3.5~5.5 mmol/mL),且随着保存时间的增加,K+浓度也相应增加,但在保存不同的时段,K+上升的速率存在差异。结论红细胞悬浮液电解质动态变化模型的建立有助于指导血液的库存控制,输注保存21 d内的红细胞悬浮液有利于减轻患者的钾离子负荷。

  9. Relations between a novel, reliable, and rapid index of arterial compliance (PP-HDI) and well-established inidices of arterial blood pressure (ABP) in a sample of hypertensive elderly subjects.

    Science.gov (United States)

    Bergamini, L; Finelli, M E; Bendini, C; Ferrari, E; Veschi, M; Neviani, F; Manni, B; Pelosi, A; Rioli, G; Neri, M

    2009-01-01

    Hypertension is a risk factor for a long-lasting arterial wall-remodelling leading to stiffness. The rapid method measuring the pulse pressure (PP) by means of the tool of Hypertension Diagnostic Instruments (HDI) called PP-HDI, overcomes some of the problems arising with more-time consuming methods, like ambulatory blood pressure monitoring (ABPM), and give information about the elasticity of the arterial walls. We studied the relationship between the PP-HDI, the large artery compliance (LA-C) and small artery compliance (SA-C) and few well-established indices of arterial blood pressure (ABP) in a sample of 75 hypertensive subjects, aged 65 years and over. Significant correlations between LA-C and heart rate (HR), PP-ABPM and PP-HDI were found. SA-C relates with HR and systolic blood pressure (SBP) measured in lying and standing positions. Applying a stepwise regression analysis, we found that LA-C variance stems from PP-HDI and HR, while SA-C variance stems from SBP in lying position. Receiver operator characteristic (ROC) curves for thresholds of PP showed that PP-HDI reached levels of sensitivity/specificity similar to PP-ABPM. In conclusion, surveillance of ABP through hemo-dynamic indices, in particular of SBP, is essential, nevertheless the advantage of this control is not known in an elderly population where the organ damage is already evident. PP needs necessarily an instrumental measurement. The PP-HDI result is similar in reliability with respect to PPABPM, but is more rapid and well applicable in an elderly population.

  10. Recommendations and Justifications for Modifications for Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office Federal Facility Agreement and Consent Order, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    2008-02-01

    This document is part of an effort to re-evaluate all FFACO URs against the current RBCA criteria (referred to in this document as the Industrial Sites [IS] RBCA process) as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006c). Based on this evaluation, the URs were sorted into the following categories: 1. Where sufficient information exists to determine that the current UR is consistent with the RCBA criteria 2. Where sufficient information exists to determine that the current UR may be removed or downgraded based on RCBA criteria. 3. Where sufficient information does not exist to evaluate the current UR against the RCBA criteria. After reviewing all the existing FFACO URs, the 49 URs addressed in this document have sufficient information to determine that these current URs may be removed or downgraded based on RCBA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RCBA criteria.

  11. Idiopathic interstitial pneumonias: Classification revision

    Directory of Open Access Journals (Sweden)

    Demosthenes Bouros MD, PhD, FCCP

    2010-01-01

    Full Text Available The American Thoracic Society (ATS, the European Respiratory Society (ERS and the Japan Respiratory Society (JRS are planning a revision of the 2002 ATS/ERS International Multidisciplinary Classification of Idiopathic Interstitial Pneumonias (IIPs1. In two years’ time it will be 10 years since its publication and with a view to publishing the revision after 10 years (i.e., in 2012, a steering committee has been established, which met in New Orleans during ATS congress in May 2010 and more recently in Barcelona during the ERS congress (Photo. The committee will meet again during the ATS and the ERS congresses that will be held in the next two years, with an additional meeting in Modena, Italy, in Αpril 2011.

  12. Code development of the national hemovigilance system and expansion strategies for hospital blood banks

    Directory of Open Access Journals (Sweden)

    Kim Jeongeun

    2012-01-01

    Full Text Available Objectives : The aims of this study were to develop reportable event codes that are applicable to the national hemovigilance systems for hospital blood banks, and to present expansion strategies for the blood banks. Materials and Methods : The data were obtained from a literature review and expert consultation, followed by adding to and revising the established hemovigilance code system and guidelines to develop reportable event codes for hospital blood banks. The Medical Error Reporting System-Transfusion Medicine developed in the US and other codes of reportable events were added to the Korean version of the Biologic Products Deviation Report (BPDR developed by the Korean Red Cross Blood Safety Administration, then using these codes, mapping work was conducted. We deduced outcomes suitable for practice, referred to the results of the advisory councils, and conducted a survey with experts and blood banks practitioners. Results : We developed reportable event codes that were applicable to hospital blood banks and could cover blood safety - from blood product safety to blood transfusion safety - and also presented expansion strategies for hospital blood banks. Conclusion : It was necessary to add 10 major categories to the blood transfusion safety stage and 97 reportable event codes to the blood safety stage. Contextualized solutions were presented on 9 categories of expansion strategies of hemovigilance system for the hospital blood banks.

  13. Belief Revision and Verisimilitude Based on Preference and Truth Orderings

    NARCIS (Netherlands)

    Renardel de Lavalette, Gerard R.; Zwart, Sjoerd D.

    2011-01-01

    In this rather technical paper we establish a useful combination of belief revision and verisimilitude according to which better theories provide better predictions, and revising with more verisimilar data results in theories that are closer to the truth. Moreover, this paper presents two alternativ

  14. 产前非创伤性检测胎儿kidd血型基因型方法的建立及其应用%Establishment of noninvasive prenatal diagnosis method for fetal Kidd blood group genotype and its application

    Institute of Scientific and Technical Information of China (English)

    秦斐; 何吉; 王芳; 陈舒; 刘晋辉; 朱发明; 吕杭军; 严力行

    2011-01-01

    目的:利用孕妇血浆中游离胎儿DNA建立产前非创伤性诊断Kidd血型基因型的实时荧光PCR技术(RQ-PCR).方法:采用QIAamp试剂盒抽提孕妇血浆DNA,利用短串联重复序列(STR)确认提取物存在胎儿DNA,利用RQ-PCR检测胎儿Kidd基因型.采用血清学方法检测婴儿脐带血Kidd表型,回顾性评价基因分型方法的准确性.结果:在182例孕妇中筛选出96例纯合子Kidd表型,进一步通过鉴定其婴儿脐带血Kidd表型,从中筛选得到46例标本孕妇纯合子表型而婴儿脐带血JK(a+b+)表型.在这46例孕妇血浆DNA标本中能检出父源性等位基因的标本为38例,孕妇表型分别为6例JK(a+b-)和32例JK(a-b+).38例孕妇血浆DNA标本用RQ-PCR法均检测到了孕妇所不具备的JK * B或JK*A父源性等位基因,其结果与婴儿脐带血Kidd表型相吻合.结论:本实验建立的RQ-PCR非创伤性产前诊断胎儿Kidd血型基因型是可行的,当孕妇为纯合子时可通过产前非创伤性基因分型辅助诊断和预防新生儿溶血病.%Objective:To establish the real time fluorescence quantitative PCR (RQ -PCR) of noninvasive prenatal diagnosis for fetal Kidd blood group genotype from cell -free fetal DNA in maternal plasma. Methods: QIAamp DNA Kit was used to extract DNA from maternal plasma samples. The existence of fetal DNA was confirmed by short tandem repeat (STR) technique.The fetal Kidd genotype was examined by RQ - PCR from cell - free fetal DNA in maternal plasma. The Kidd phenotype of fetal cord blood samples was determined by serological assay and the concordance of the results between RQ - PCR and serological assay were analyzed. Results: 96 samples with Kidd homozygote phenotypes were chosen from 182 maternal peripheral blood samples. 46 samples with mother homozygote phenotype and fetal Jk( a + b + ) phenotype were obtained by further analyzed the Kidd phenotypes from fetal cord blood samples. 38 samples were found to show the paternally inherited

  15. Revised dietary guidelines for Koreans.

    Science.gov (United States)

    Jang, Young Ai; Lee, Haeng Shin; Kim, Bok Hee; Lee, Yoonna; Lee, Hae Jeung; Moon, Jae Jin; Kim, Cho-il

    2008-01-01

    With rapidly changing dietary environment, dietary guidelines for Koreans were revised and relevant action guides were developed. First, the Dietary Guidelines Advisory Committee was established with experts and government officials from the fields of nutrition, preventive medicine, health promotion, agriculture, education and environment. The Committee set dietary goals for Koreans aiming for a better nutrition state of all after a thorough review and analysis of recent information related to nutritional status and/or problems of Korean population, changes in food production/supply, disease pattern, health policy and agricultural policy. Then, the revised dietary guidelines were proposed to accomplish these goals in addition to 6 different sets of dietary action guides to accommodate specific nutrition and health problems of respective age groups. Subsequently, these guidelines and guides were subjected to the focus group review, consumer perception surveys, and a public hearing for general and professional comments. Lastly, the language was clarified in terms of public understanding and phraseology. The revised Dietary guidelines for Koreans are as follows: eat a variety of grains, vegetables, fruits, fish, meat, poultry and dairy products; choose salt-preserved foods less, and use less salt when you prepare foods; increase physical activity for a healthy weight, and balance what you eat with your activity; enjoy every meal, and do not skip breakfast; if you drink alcoholic beverages, do so in moderation; prepare foods properly, and order sensible amounts; enjoy our rice-based diet.

  16. Establishment of radiation dose-response curve based on in vitro irradiation of peripheral blood samples by X-ray%离体人外周血血X射线照射后剂量效应曲线的建立

    Institute of Scientific and Technical Information of China (English)

    李广伟; 李峰生

    2012-01-01

    目的 建立准确估算受辐射照射者辐射剂量的方法.方法 采用X射线照射离体人外周血,一步法培养外周血淋巴细胞56 h后收获制片,检测染色体"双着丝粒(dic)+环(r)"畸变率,拟合剂量效应曲线.结果 畸变率随照射剂量增加而增加,存在明显的剂量效应,剂量效应曲线回归方程为y=0.020 8x2+0.102 8x-0.024 8,r2=0.995 3(P<0.05).结论 通过建立X射线照射离体人外周血后的剂量效应曲线,能准确估算受照辐射剂量.%Objective To establish the method of estimating accurately radiation dose of the individuals exposed to ionizing-radi-ation. Methods The blood samples in vitro were irradiated by X-ray,then cultured using one-step method for 56 hours. According to the chromosomal aberration rate(including dicentric chromosome and ring) , radiation dose-response curve was fitted. Results The chromosomal aberration rate induced by the different radiation doses increased along with the increase of radiation dose, and there was an apparent dose-response relationship,the radiation dose-response curve regression equation:y=0. 020 8x2+0. 102 8x-0. 024 8. Conclusion The dose of the individual exposed to ionizing-radiation could be estimated accurately according to the radiation dose-response curve that might be fitted by the blood samples in vitro irradiated by X-ray.

  17. Blood sugar test - blood

    Science.gov (United States)

    ... blood glucose level ( hypoglycemia ) may be due to: Hypopituitarism (a pituitary gland disorder) Underactive thyroid gland or ... tonic-clonic seizure Glucagon blood test Glucagonoma Hyperthyroidism Hypopituitarism Hypothyroidism Insulinoma Low blood sugar Multiple endocrine neoplasia ( ...

  18. Writing as Revision.

    Science.gov (United States)

    Della-Piana, Gabriel M.; Endo, George T.

    This proposal for a longitudinal experimental study with a treatment intervention focuses on the process of writing as revision. Revision refers to the process which occurs prior to and throughout the writing of a work, rather than the final editing. According to this process, the writer goes through five stages: preconceptions concerning style…

  19. 气虚血瘀型Corti器毛细胞损伤动物模型的建立%Establishing hair cell damage model in the animal Corti organ with Qi deficiency and blood stasis

    Institute of Scientific and Technical Information of China (English)

    彭桂原; 李松键; 杨黎; 杨朝杰; 谭串

    2016-01-01

    背景:随着中医药对耳鸣耳聋的疗效越来越受到重视,但对其机制尚缺乏系统深入的研究,利用动物模型进行中医药治疗耳鸣耳聋的机制探索是非常有意义的研究方向。  目的:建立一种气虚血瘀证型的Corti器毛细胞损伤动物(豚鼠)模型并评价其效果。  方法:12只成年豚鼠按随机数字表法分为正常对照组和造模组。造模组首先采用改良耗气破气加饥饱失常法处理15 d进行气虚造模,之后以光化学反应法复制血瘀Corti器毛细胞损伤模型;正常对照组不干预。造模后检测两组豚鼠血清的D-木糖浓度,行耳声发射DPOAE测试,并观察光镜下耳蜗组织形态。  结果与结论:①与正常对照组相比,造模组血清D-木糖浓度较低(P OBJECTIVE:To establish hair cel damage model in the Corti organ with Qi deficiency and blood stasis in guinea pigs, and to assess its effects. METHODS:Twelve adult guinea pigs were randomly divided into normal control and model groups by random number table method. Guinea pigs in the model group were firstly treated with the modified relieving stagnated Qi and abnormal starvation for 15 days to model Qi deficiency, and then stimulated hair cel damage with blood stasis by photochemical induction. The controls received no intervention. Subsequently, the detection of serum D-xylose content and DPOAE test were performed, and the cochlea morphology was observed under light microscope. RESULTS AND CONCLUSION:(1) The serum D-xylose content in the model group was significantly lower than that in the normal control group (P<0.01). (2) DPOAE test revealed that the amplitudes of 1 560 and 3 125 Hz in the model group were lower than those in the normal control group and before modeling (P<0.01). (3) In the model group, hemangiectasis and microthrombosis appeared in the spiral ligament, microvascular basement membrane and modiolus capil aries, and stria vascularis

  20. Establishment of a Rapid Method for Extracting Human Genomic DNA from Peripheral Clotted Blood%一种快速、经济提取外周凝血基因组DNA方法的建立

    Institute of Scientific and Technical Information of China (English)

    许丽娟; 马骁; 王洋阳; 王静; 潘晴; 刘梅

    2011-01-01

    Objective: To establish a rapid, economical method for extracting genotnic DNA from peripheral clotted blood. Methods: Explore a optimum homogenate condition, homogenate the clotted blood, extracting the genomic DNA by KI method. Use agarose gel electrophoresis, single PCR and multiplex PCR detect the genomic DNA extraction yield and quality. And compared with the traditional extraction methods, Proteinase K digestion method and KI method which extract DNA from anti-coagulated blood. Results: The optimum homogenate condition is 39000 rmp and 15 seconds. The genomic DNA was extracted under this condition has good integrity. There is no significant difference of purity and yield between this method and Proteinase K digestion and KI method. Single PCR and multiplex PCR also obtained good amplification results. Conclusion: Compared with traditional extraction methods (Proteinase K digestion method),this method can save time and cost, which can extract DNA rapidly,economical and effectively,and can be used in clinical and research analysis, and can solve the blood genomic DNA sources of some of the research institutions.%目的:建立一种经济、快速且高质量提取人体外周凝血DNA的方法.方法:摸索最佳的匀浆条件,对外周凝血块进行匀浆,采用KI法对匀浆液进行基因组DNA的提取,通过凝胶电泳、单重PCR和多重PCR检测凝血基因组DNA的提取产量和质量,并分别与常规的凝血基因组DNA提取方法,即蛋白酶K消化法,以及提取抗凝血基因组DNA的KI法进行比较分析.结果:最佳的匀浆条件为:39000 rmp,15秒.在此条件下提取的基因组DNA完整性好,纯度和产量与蛋白酶K消化法提取凝血DNA和KI法提取抗凝血DNA的结果相比,没有统计学差异.单重PCR和多重PCR也获得了理想的扩增结果.结论:与常规的外周凝血提取方法相比(蛋白酶K消化法),本方法节省了时间和成本,能快速、经济、有效地提取外周凝血基因组DNA,可

  1. Establishment and Revision of National Ambient Air Quality Standards for Particulate Matters in Europe and US and the Practical Usefulness to China%欧美制订颗粒污染物环境空气质量标准的历程及对我国的借鉴

    Institute of Scientific and Technical Information of China (English)

    杨立新

    2015-01-01

    The principles and methodology of formulating ambient air quality objectives and establishing ambient air quality criteria and standards for particulate matters in Euorpe and USA were reviewed.The experience of controlling fine particulates pollution as well as the theories, mothods and progresses of establishing and revising ambient air quality standards for fine particulates in the developed countries were analyzed.Combining with the the charaterisitics of fine particulate pollution and the current status of research and development, it is suggested that multi-disciplines research organizations could be organized and supported by administration agency to carry out joint key research projects, provide scientific research conclussions and then publish China′s own national ambient air quality criteria documents for particulate matters reflecting the latest scientific knowledge.%通过回顾欧美制订空气质量目标、建立颗粒物环境空气质量基准和标准的原则和方法,借鉴发达国家治理大气细颗粒污染物的成功经验和制(修)订大气细颗粒物环境质量标准的理论、方法和历程,结合我国空气颗粒污染物的特征和科学研究的现状,提出应由国家主管部门通过顶层设计,组织相关研究机构开展联合攻关研究,提供科学研究结论,在此基础上出版我国颗粒物环境空气质量基准文件。

  2. Katz's revisability paradox dissolved

    NARCIS (Netherlands)

    Tamminga, Allard; Verhaegh, Sander

    2013-01-01

    Quine's holistic empiricist account of scientific inquiry can be characterized by three constitutive principles: noncontradiction, universal revisability and pragmatic ordering. We show that these constitutive principles cannot be regarded as statements within a holistic empiricist's scientific theo

  3. Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  4. Scar revision - slideshow

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/presentations/100098.htm Scar revision - series—Normal anatomy To use the sharing ... entire body, and acts as a protective barrier. Scar tissue forms as skin heals after an injury ( ...

  5. 全血中伤寒沙门菌RT-LAMP检测方法的建立%Establishment of RT-LAMP assay to detect Salmonella Typhi in blood

    Institute of Scientific and Technical Information of China (English)

    樊粉霞; 王淑京; 娄静; 陈建才; 聂艳妮; 阚飙; 闫梅英

    2012-01-01

    Objective To establish reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay to detect Salmonella Typhi in blood. Methods A set of six specific primers recognizing distinct regions of fliC-d gene of S. Typhi were designed and modified to establish RT-LAMP assay and the specificity and sensitivity of RT-LAMP with RNA as template were evaluated and verified by detecting cultured Salmonella and non-Salmonella strains in 48 serotypes, the non-Salmonella strains causing diarrhea and the strains of 8 bacteria inducing bacteremia with fever as main symptom. The simulated blood specimens supplemented with S. Typhi were tested with RT-LAMP assay, and the detection limit of RT-LAMP was compared with that of real-time PCR. Results The RT-LAMP assay successfully detected fliC-d gene of S. Typhi within 30 to 60 minutes at 65 t. Totally 44 strains of S. Typhi were detected to be positive. Except 4 rare serotypes of non-salmonella were positive in amplification, the amplification of the strains of non-Salmonella in 30 serotypes, the strains of 5 pathogens causing diarrhea and the strains of 8 bacteria causing bacteremia with fever as main symptom were negative. In the detection of total RNA from pure cultured isolates, the detection limit of RT-LAMP was 0.5 pg per reaction (97copies per reaction). In the extracting nucleotide from simulated blood, the sensitivity was 1 cfu /ml, which was 100 fold higher than that of real time PCR. Conclusion The RT-LAMP assay for detecting 5. Typhi with high sensitivity and specificity was established, which would be suitable for rapid diagnosis of S. Typhi infection and identifying pathogen of fever with unknown origin , and can be used in early diagnosis, prevention/control and treatment of typhoid fever.%目的 建立反转录-环介导等温核酸扩增(RT-LAMP)方法特异检测伤寒沙门菌.方法 针对伤寒沙门菌fliC-d基因设计6条特异性引物,通过优化反应条件,建立检测

  6. Supplemental design requirements document, Project W026. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Weidert, J.R.

    1993-10-08

    This document supplements and extends the Functional Design Criteria, SP-W026-FDC-001, for the Waste Receiving and Processing Facility (WRAP), Module 1. It provides additional detailed requirements, summarizes key Westinghouse Hanford Company design guidance, and establishes baseline technical agreements to be used in definitive design of the WRAP-1 facility. Revision 3 of the Supplemental Design Requirements Document has been assigned an Impact Level of 3ESQ based on the content of the entire revision. The actual changes made from Revision 2 have an Impact Level of 3S and the basis for these changes was previously reviewed and approved per WHC correspondence No. 9355770.

  7. Potentialities of Revised Quantum Electrodynamics

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2013-10-01

    Full Text Available The potentialities of a revised quantum electrodynamic theory (RQED earlier established by the author are reconsidered, also in respect to other fundamental theories such as those by Dirac and Higgs. The RQED theory is characterized by intrinsic linear symmetry breaking due to a nonzero divergence of the electric field strength in the vacuum state, as supported by the Zero Point Energy and the experimentally confirmed Casimir force. It includes the results of electron spin and antimatter by Dirac, as well as the rest mass of elementary particles predicted by Higgs in terms of spontaneous nonlinear symmetry breaking. It will here be put into doubt whether the approach by Higgs is the only theory which becomes necessary for explaining the particle rest masses. In addition, RQED theory leads to new results beyond those being available from the theories by Dirac, Higgs and the Standard Model, such as in applications to leptons and the photon.

  8. Revising and editing for translators

    CERN Document Server

    Mossop, Brian

    2014-01-01

    Revising and Editing for Translators provides guidance and learning materials for translation students learning to edit texts written by others, and professional translators wishing to improve their self-revision ability or learning to revise the work of others. Editing is understood as making corrections and improvements to texts, with particular attention to tailoring them to the given readership. Revising is this same task applied to draft translations. The linguistic work of editors and revisers is related to the professional situations in which they work. Mossop offers in-depth coverage of a wide range of topics, including copyediting, style editing, structural editing, checking for consistency, revising procedures and principles, and translation quality assessment. This third edition provides extended coverage of computer aids for revisers, and of the different degrees of revision suited to different texts. The inclusion of suggested activities and exercises, numerous real-world examples, a proposed gra...

  9. Money for Blood and Markets for Blood.

    Science.gov (United States)

    Derpmann, Simon; Quante, Michael

    2015-12-01

    Ontario's Bill 178 proposing a Voluntary Blood Donations Act declares the offer or acceptance of payment for the donation of blood a legal offence and makes it subject to penalty. The bill reinvigorates a fundamental debate about the ethical problems associated with the payment of money for blood. Scarcity of blood donors is a recurring problem in most health systems, and monetary remuneration of the willingness to donate blood is regularly discussed--and sometimes practiced--as a means to overcome scarcity in blood. However, making blood an object of economic exchange has long aroused ethical concerns that often refer to the specific meaning of blood. From the perspective of a modern understanding of money as a metric of economic value, the exchange of money for blood--shed or given--is seen as ethically troubling, because it appears to imply a commensurability of the value of human life and economic wealth. In this paper, we begin with a general taxonomy of the types of arguments that speak in favour or against compensating donors for giving blood. We then describe the context in which the discussion about payment for blood arises, and of the specific aims and concerns that are brought forward in this context. This is used to reconstruct the normative background that supports the rejection of payment for blood as it is envisaged in Bill 178 and the aims of the proposal. We then argue that while a payment indeed changes the nature of a blood donation in an ethically considerable way, we do not believe that decisive arguments against the monetary remuneration of blood donations can be substantiated, at least not independently of assuming specific societal circumstances. Thus it may be possible to establish a stable and safe blood supply through just gratification while at the same time taking strong provisions against social disconnection, injustice, exploitation or heteronomy.

  10. Revision of the Sarcospermataceae

    NARCIS (Netherlands)

    Lam, H.J.; Varossieau, W.W.

    1938-01-01

    The genus Sarcosperma was excluded from the Sapotaceae by the first-named writer in 1925, the group being considered as of family rank. In 1926 the same author published a concise and fragmentary revision of the monotypic order, in which two new Malaysian species were described. The continental spec

  11. Revision without ordinals

    NARCIS (Netherlands)

    Rivello, Edoardo

    2013-01-01

    We show that Herzberger’s and Gupta’s revision theories of truth can be recast in purely inductive terms, without any appeal neither to the transfinite ordinal numbers nor to the axiom of Choice. The result is presented in an abstract and general setting, emphasising both its validity for a wide ran

  12. Blood smear

    Science.gov (United States)

    ... some red blood cells shaped like spheres ( hereditary spherocytosis ) Increased breakdown of RBCs Presence of RBCs with ... normal Red blood cells, elliptocytosis Red blood cells, spherocytosis Acute lymphocytic leukemia - photomicrograph Red blood cells, multiple ...

  13. Blood culture

    Science.gov (United States)

    Culture - blood ... A blood sample is needed . The site where blood will be drawn is first cleaned with an antiseptic such ... organism from the skin getting into (contaminating) the blood sample and causing a false-positive result (see ...

  14. Blood Thinners

    Science.gov (United States)

    If you have some kinds of heart or blood vessel disease, or if you have poor blood flow to your brain, your doctor may recommend that you take a blood thinner. Blood thinners reduce the risk of heart ...

  15. Blood transfusions

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000431.htm Blood transfusions To use the sharing features on this ... several sources of blood which are described below. Blood From the Public (Volunteer Blood Donation) The most ...

  16. [An overview on the collation and revision of medical books by the Bureau for Revising Medical Books in the Northern Song Dynasty].

    Science.gov (United States)

    Meng, Yongliang; Liang, Yongxuan

    2014-07-01

    The Bureau for Revising Medical Books was a temporary agency established by the government of the Northern Song Dynasty in 1057, the 2nd year of Jiayou of Emperor Renzong, exclusively for the edition, revision and publishing of ancient medical books. 11 medical books were revised and edited by 13 Bureau members in a period of 12 years until 1069, the 2nd year of Xining of Emperor ShenZong, which eventually became the final versions until today. 8 medical books were initially planned for the revision, but 11 were actually completed in the end. The time for completing a revision varied from over 10 years at most to less than 1 year at least. Instead of working in the office, the officers of the Bureau for Revising Medical Books did their works at home. The members of the said Bureau came from the Tiju officer of the Bureau for Revising Medical Books and the officials of revising medical books, consisting of both Confucian ministers and medical officers. Confucian ministers played an important role in revising medical books. The Bureau had a strict workflow in electing revising officials, making the project, and the determination of the principles and arrangements of the tasks of editing and proofreading.

  17. Financial analysis of revision knee surgery based on NHS tariffs and hospital costs: does it pay to provide a revision service?

    Science.gov (United States)

    Kallala, R F; Vanhegan, I S; Ibrahim, M S; Sarmah, S; Haddad, F S

    2015-02-01

    Revision total knee arthroplasty (TKA) is a complex procedure which carries both a greater risk for patients and greater cost for the treating hospital than does a primary TKA. As well as the increased cost of peri-operative investigations, blood transfusions, surgical instrumentation, implants and operating time, there is a well-documented increased length of stay which accounts for most of the actual costs associated with surgery. We compared revision surgery for infection with revision for other causes (pain, instability, aseptic loosening and fracture). Complete clinical, demographic and economic data were obtained for 168 consecutive revision TKAs performed at a tertiary referral centre between 2005 and 2012. Revision surgery for infection was associated with a mean length of stay more than double that of aseptic cases (21.5 vs 9.5 days, p < 0.0001). The mean cost of a revision for infection was more than three times that of an aseptic revision (£30 011 (sd 4514) vs £9655 (sd 599.7), p < 0.0001). Current NHS tariffs do not fully reimburse the increased costs of providing a revision knee surgery service. Moreover, especially as greater costs are incurred for infected cases. These losses may adversely affect the provision of revision surgery in the NHS.

  18. The effects of hydroxyapatite coating and bone allograft on fixation of loaded experimental primary and revision implants

    DEFF Research Database (Denmark)

    Søballe, Kjeld; Mouzin, Olivier R G; Kidder, Louis A;

    2003-01-01

    We used our established experimental model of revision joint replacement to examine the roles of hydroxyapatite coating and bone graft in improving the fixation of revision implants. The revision protocol uses the Søballe micromotion device in a preliminary 8-week period of implant instability...... for the presence of particulate polyethylene. During this procedure, a sclerotic endosteal bone rim forms, and a dense fibrous membrane is engendered, having macrophages with ingested polyethylene and high levels of inflammatory cytokines. At the time of revision after 8 weeks, the cavity is revised with either...... in each of the 8 treatment groups (total 64 implants in 32 dogs). The observation period was 4 weeks after revision. Outcome measures are based on histomorphometry and mechanical pushout properties. The revision setting was always inferior to its primary counterpart. Bone graft improved the revision...

  19. 78 FR 7703 - Revisions to the California State Implementation Plan, South Coast Air Quality Management...

    Science.gov (United States)

    2013-02-04

    .... SUMMARY: EPA is proposing to approve a revision to the South Coast Air Quality Management District (SCAQMD... designed to implement the 2003 Air Quality Management Plan (AQMP) control measure, WST-01, and establish... AGENCY 40 CFR Part 52 Revisions to the California State Implementation Plan, South Coast Air...

  20. Blood Donation

    Science.gov (United States)

    Tests and Procedures Blood donation By Mayo Clinic Staff Blood donation is a voluntary procedure. You agree to have blood drawn so that it can ... have a disease that requires blood components. Blood donation makes all of this possible. There are several ...

  1. MARKOWITZ STRATEGIES REVISED

    Institute of Scientific and Technical Information of China (English)

    Yan Jia-an; Zhou Xunyu

    2009-01-01

    Continuous-time Markowitz's mean-variance efficient strategies are modified by parameterizing a critical quantity. It is shown that these parameterized Markowitz strategies could reach the original mean target with arbitrarily high probabilities. This, in turn, motivates the introduction of certain stopped strategies where stock holdings are liquidated whenever the parameterized Markowitz strategies reach the present value of the mean target. The risk aspect of the revised Markowitz strategies are examined via expected discounted loss from the initial budget. A new portfolio selection model is suggested based on the results of the paper.

  2. Donating Blood

    Science.gov (United States)

    ... can't get an infection or disease from giving blood. The needles and other equipment used are sterile ... part of blood (plasma) within 72 hours after giving blood. It generally takes about 4–8 weeks to ...

  3. Perioperative complications in revision hip surgery.

    Science.gov (United States)

    Thomasson, E; Guingand, O; Terracher, R; Mazel, C

    2001-01-01

    Revision hip surgery now constitutes 10-30% of all joint procedures. The morbidity and associated with this demanding operation are not well established. The goal of this paper is to determine these rates and to identify some predictive factors. The complication rate ranges from 31,5 to more than 77% in the literature. Life threatening complications represent 1,8 to 8% of these, leading to death in about 1,6%. ASA score and age above 75 appear to be correlated with medical complications. The injection rate varies from 1 to 5,8%, and may be as high as 14% in cases with a past history of infection. Heterotopic ossification occurred in 13 to 65%, reaching severity in 3,3 to 8,3%. Surgical complications include dislocation and femoral injuries. Dislocations occur in almost 10%, leading to revision in1-4,2%. Age and the number of previous surgical operations appear to be significant risk factors. Femoral injuries (perforations or femoral fractures) occur in 6-37%, especially in impaction grafting technique and when uncemented implants are used. Age over 75 years and femoral defects appear to be significant risk factors for femoral fractures. The rate of complications in revision hip surgery continues to be high, but successful clinical outcome can be attained even in elderly patients. Attentive preoperative exams, good prevention of technical pitfalls, the experience of the surgeon and the use of specific tools may decrease these complications and make this demanding procedure safer.

  4. 77 FR 6566 - Agency Information Collection Activities; Proposed Collection; Comment Request; Revisions to...

    Science.gov (United States)

    2012-02-08

    ...The Food and Drug Administration (FDA) is correcting a notice that appeared in the Federal Register of December 30, 2011. In the Federal Register of December 30, 2011, FDA published a notice entitled ``Agency Information Collection Activities; Proposed Collection; Comment Request; Revisions to Labeling Requirements for Blood and Blood Components, Including Source Plasma,'' which provided......

  5. 77 FR 23396 - Revisions to the Requirements for Authority To Manufacture and Distribute Postage Evidencing Systems

    Science.gov (United States)

    2012-04-19

    ... 501--AUTHORIZATION TO MANUFACTURE AND DISTRIBUTE POSTAGE EVIDENCING SYSTEMS 0 1. The authority... 501 Revisions to the Requirements for Authority To Manufacture and Distribute Postage Evidencing Systems AGENCY: Postal Service TM . ACTION: Final rule. SUMMARY: This rule establishes the...

  6. Surgical scar revision: An overview

    Directory of Open Access Journals (Sweden)

    Shilpa Garg

    2014-01-01

    Full Text Available Scar formation is an inevitable consequence of wound healing from either a traumatic or a surgical intervention. The aesthetic appearance of a scar is the most important criteria to judge the surgical outcome. An understanding of the anatomy and wound healing along with experience, meticulous planning and technique can reduce complications and improve the surgical outcome. Scar revision does not erase a scar but helps to make it less noticeable and more acceptable. Both surgical and non-surgical techniques, used either alone or in combination can be used for revising a scar. In planning a scar revision surgeon should decide on when to act and the type of technique to use for scar revision to get an aesthetically pleasing outcome. This review article provides overview of methods applied for facial scar revision. This predominantly covers surgical methods.

  7. The heritability of blood donation

    DEFF Research Database (Denmark)

    Pedersen, Ole Birger; Axel, Skytthe; Rostgaard, Klaus

    2015-01-01

    BACKGROUND: Voluntary blood donation is believed to be mostly motivated by altruism. Because studies have suggested that altruistic personality is determined by both genetic and environmental factors, we speculated that willingness to donate blood could also be governed by constitutional factors...... active Danish blood donors from 2002 to 2012, to establish blood donor status for Danish twins, who at age 17 years became eligible for donation in 2002 or later. Casewise concordance in monozygotic (MZ) and dizygotic (DZ) twins were presented and heritability was estimated in Mx by variance component...... to donate blood, respectively. CONCLUSION: Becoming a volunteer blood donor is determined by both genetic and environmental factors shared within families....

  8. Analytical model for calculating indeterminate results interval of screening tests, the effect on seroconversion window period: a brief evaluation of the impact of uncertain results on the blood establishment budget.

    Science.gov (United States)

    Pereira, Paulo; Westgard, James O; Encarnação, Pedro; Seghatchian, Jerard

    2014-10-01

    The evaluation of measurement uncertainty is not required by the European Union regulation or blood establishments’ laboratory tests. However, it is required for tests accredited by ISO 15189. Also, the forthcoming ISO 9001 edition requires “risk based thinking” with risk described as “the effect of uncertainty on an expected result”. ISO recommends GUM models for determination of measurement uncertainty, but their application is not intended for ordinal value measurements, such as what happens with screening test binary results. This article reviews, discusses and proposes concepts intended for measurement uncertainty of screening test results. The precision model focuses on cutoff level allowing the evaluation of the indeterminate interval using analytical sources of variance. The intervalis considered in the estimation of the seroconversion window period. The delta-value of patients and healthy subjects’ samples allows ranking two tests according to the probability of the two classes of indeterminate results: chance of false negative results and chance of false positive results (waste on budget).

  9. Philippines revises power plans

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, D.

    1988-02-01

    Following an unexpected surge in electricity demand the Philippines has revised its medium term power development programme. The sharp increase in electricity consumption follows three years of slack demand due to civil disturbances before the end of the Macros administration and the election of Corazon Aquino as President in 1986. Originally, the Aquino government's medium term power development plans called for about 500MW of generating capacity to be installed between 1986 and 1992. The three proposed plants were scheduled for commissioning in 1991 and 1992. However, a spurt in power demand growth during the past nine months has caused concern among industrialists that power shortages could occur by the end of the decade. So additional capacity will be installed to prevent an anticipated shortfall in electricity supplies by the early 1990s.

  10. A study on scar revision

    Directory of Open Access Journals (Sweden)

    Ashutosh Talwar

    2016-04-01

    Full Text Available Introduction: Scars are psychologically distressing for the patients and have an impact on the quality of life and self esteem of the patients. Scar revision is an aesthetic skill which is mastered by plastic surgeons and encroached now by dermatosurgeons. Scars on the face are aesthetically unacceptable and various techniques have been improvised for making a scar aesthetically acceptable. Various types of techniques are used for scar revision like W plasty, Z plasty and VY plasty. Aims: To see the efficacy of various scar revision techniques including Z plasty, VY plasty and W plasty in 30 patients with disfiguring scars. Methods: We selected twenty patients of disfiguring scars for the study. The scars from various causes including trauma and burns were included in our study. Various techniques of scar revision include Z plasty, W plasty and VY plasty were performed according to the type and site of scar. Results: Male: female was 1.5: 1. The scar revision surgery yielded excellent results with minimal complications including haematoma formation, secondary infection and delayed healing seen in 5% patients each. Regarding the efficacy of scar revision, excellent improvement was seen in 60% patients, moderate improvement was seen in 30% patients and mild improvement was seen in 10% patients. Conclusions: Dermatologists can employ a number of surgical scar revision techniques. While some are better suited to treat specific types of scars, they can be used in combination with each other or with adjunctive therapies to achieve optimal results.

  11. Artificial blood

    Directory of Open Access Journals (Sweden)

    Sarkar Suman

    2008-01-01

    Full Text Available Artificial blood is a product made to act as a substitute for red blood cells. While true blood serves many different functions, artificial blood is designed for the sole purpose of transporting oxygen and carbon dioxide throughout the body. Depending on the type of artificial blood, it can be produced in different ways using synthetic production, chemical isolation, or recombinant biochemical technology. Development of the first blood substitutes dates back to the early 1600s, and the search for the ideal blood substitute continues. Various manufacturers have products in clinical trials; however, no truly safe and effective artificial blood product is currently marketed. It is anticipated that when an artificial blood product is available, it will have annual sales of over $7.6 billion in the United States alone.

  12. Artificial blood.

    Science.gov (United States)

    Sarkar, Suman

    2008-07-01

    Artificial blood is a product made to act as a substitute for red blood cells. While true blood serves many different functions, artificial blood is designed for the sole purpose of transporting oxygen and carbon dioxide throughout the body. Depending on the type of artificial blood, it can be produced in different ways using synthetic production, chemical isolation, or recombinant biochemical technology. Development of the first blood substitutes dates back to the early 1600s, and the search for the ideal blood substitute continues. Various manufacturers have products in clinical trials; however, no truly safe and effective artificial blood product is currently marketed. It is anticipated that when an artificial blood product is available, it will have annual sales of over $7.6 billion in the United States alone.

  13. The Use of Epoetin-α in Revision Knee Arthroplasty

    Directory of Open Access Journals (Sweden)

    Lawrence A. Delasotta

    2012-01-01

    Full Text Available Introduction. To evaluate the efficacy of epoetin-α prior to revision total knee arthroplasty, we hypothesized that epoetin-α will reduce blood transfusion. Methods. Eighty-one patients were compared in this retrospective review; twenty-eight patients received our dosing regimen. All patients were mildly anemic. Epoetin-α to control (1 : 2 patient matching occurred so that one of two attending surgeons, gender, BMI, complexity of surgery, ASA score, and age were similar between groups. The clinical triggers for blood transfusion during or after the procedure were determined based on peri- and postoperative hemoglobin levels, ASA score, and/or clinical symptoms consistent with anemia. Blood salvage was not used. Results. Blood transfusion and length of stay were lower in the study group. None of the patients who received epoetin-α underwent transfusion. Hemoglobin increased from 11.97 to 13.8, preoperatively. Hemoglobin at day of surgery and time of discharge were higher. Gender, BMI, ASA score, total and hidden blood losses, calculated blood loss, preop PLT, PT, PTT, and INR were similar between groups. One Epogen patient had an uncomplicated DVT (3.6%. Conclusions. Epoetin-α may have a role in the mildly anemic revision knee patient. It may also decrease patient length of stay allowing for earlier readiness to resume normal activities and/or meet short-term milestones. A randomized study to evaluate the direct and indirect costs of such a treatment methodology in the mildly anemic revision patient may be warranted.

  14. Revision of infected knee arthroplasties in Denmark

    DEFF Research Database (Denmark)

    Lindberg-Larsen, Martin; Jørgensen, Christoffer C; Bagger, Jens;

    2016-01-01

    Background and purpose - The surgical treatment of periprosthetic knee infection is generally either a partial revision procedure (open debridement and exchange of the tibial insert) or a 2-stage exchange arthroplasty procedure. We describe the failure rates of these procedures on a nationwide...... prosthesis with a re-revision rate due to infection of 34%, as compared to 55% in revisions of a revision prosthesis (p = 0.05). The failure rate of the 2-stage revisions was 30%. Median time interval between stages was 84 (9-597) days. 117 (54%) of the 2-stage revisions were revisions of a primary...... prosthesis with a re-revision rate due to infection of 21%, as compared to 29% in revisions of a previously revised prosthesis (p = 0.1). Overall postoperative mortality was 0.6% in high-volume centers (> 30 procedures within 2 years) as opposed to 7% in the remaining centers (p = 0.003). Interpretation...

  15. Circumcision revision in male children

    Directory of Open Access Journals (Sweden)

    Mohammed A. Al-Ghazo

    2006-08-01

    Full Text Available OBJECTIVE: To determine indications for circumcision revision and to identify the specialty of the person who performed unsatisfactory primary circumcision. MATERIALS AND METHODS: The authors reviewed medical records of 52 cases that underwent circumcision revision over a 6-year period (1998 to 2004. Sleeve surgical technique was used for revision in patients with redundant foreskin or concealed penis, penoplasty for partial or complete degloving of the penis and meatotomy for external meatal stenosis. The mean age of children was 32 months (range 6 months to 9 years. RESULTS: Most of unsatisfactory primary circumcisions (86.7% were performed by laymen. All patients who underwent circumcision revision had good to excellent cosmetic results. CONCLUSION: Primary circumcision performed by laymen carry a high complication rate and serious complications may occur. A period of training and direct supervision by physicians is required before allowing laymen to perform circumcision independently.

  16. 8岁以下儿童末梢血血红蛋白参考范围分析%Establishment of Reference Intervals for Peripheral Blood Hemoglobin Aiming at Children below 8 Years Old

    Institute of Scientific and Technical Information of China (English)

    梁有勇

    2012-01-01

    目的 建立≤8岁儿童末梢血血红蛋白的参考范围.方法 选择2010年5月-2011年10月在我院健康体检的≤8岁儿童1 514例,按年龄分组:3~12个月组429例,1~3岁组462例,4~8岁组623例.均经体检证明生长、发育正常,无慢性病史,无血红蛋白疾病史和贫血史,无血吸虫、钩虫、疟疾等寄生虫感染的贫血,无蚕豆病.检查前未接受过铁剂和输血治疗.结果 1 514个血红蛋白测定值,偏度系数为0.401,峰度系数为-0.117,呈近似正态分布.3~12个月组、1~3岁组、4~8岁组男童、女童及男女合计血红蛋白水平比较差异均有统计学意义(P<0.05).3~12个月儿童血红蛋白参考范围为96~125 g/L,1~3岁儿童血红蛋白参考范围为100~129 g/L,4~8岁男童血红蛋白参考范围为101~137 g/L,4~8岁女童血红蛋白参考范围为103~131 g/L.结论 不同年龄段应采用不同的血红蛋白参考范围,不同实验室应建立适合自己的血红蛋白的参考范围.%Objective To determine the reference intervals for hemoglobin of peripheral blood aiming at children below 8 years old. Methods We selected 1 514 healthy children below 8, inclusive who came to our hospital for physical check -up from May 2010 to October 2011 and according to their ages divided them into three groups : 3 ~ 12 months group 429 cases, 1 ~ 3 year olds group 462 cases, 4 ~ 8 years old group 623 cases. All the subjects underwent physical examination and were con -firmed normal in their growth and development , without any chronic disease , hemoglobin disease , anemia, favism and anemia caused by schistosomiasis , hookworm, malaria and they didn 't receive iron supplements or any kind of transfusion therapy. Re-sults All subjects' hemoglobin level was approximately positively distributed with coefficient of skewness being 0. 401 and coeffi-cient of kurtosis being -0. 117. The differences between males , females, males and females together in the three

  17. 呼和浩特地区 RhD 阴性献血者表型库的建立及应用%Establishment and application of the phenotype database of negative RhD blood donors in Hohhot

    Institute of Scientific and Technical Information of China (English)

    尚锦青; 贾雯婷; 苏仁娜; 崔丽敏

    2015-01-01

    Objective To understand the phenotype distribution of negative RhD blood donors in local region ,and to establish negative RhD phenotype database .Methods A total of 554 specimens screened firstly as negative RhD were confirmed by indirect antiglobulin test .Repeat donors were excluded ,the remaining specimens were 366 cases ,which were analyzed the phenotype of Rh blood .Results Distribution characteristics of negative RhD phenotype was ccdee (56 .28% ) > Ccdee (29 .51% ) > ccdEe (7 .38% )> CcdEe (3 .55% )> CCdee (3 .01% )> ccdEE (0 .27% ) ,there were no CcdEE ,CCdEe ,CCdEE detected .Conclusion The establishment of Negative RhD phenotype database is help for providing matching blood for persons with negative RhD blood or same antibody blood ,and meeting the emergency blood usage ,it′s important for scientific management and reasonable application of negative RhD blood ,and accumulate data for then negative RhD blood of the local area ,especially for Mongolian .%目的:了解该地区 RhD 阴性献血者表型分布,建立 RhD 阴性表型数据库。方法 RhD 初筛阴性的554份标本采用间接抗球蛋白试验确认。排除重复献血者后,剩余标本为366份,对其进行 Rh 血型表型分析。结果 RhD 阴性表型分布特征为ccdee(56.28%)> Ccdee (29.51%)> ccdEe (7.38%)> CcdEe (3.55%)> CCdee (3.01%)> ccdEE (0.27%),未检出 CcdEE 、CCdEe 、CCdEE 型。结论建立 RhD 阴性表型数据库,有利于为 RhD 阴性及含有 Rh 同种抗体的患者提供相匹配血液,满足其急救用血,且对科学管理 RhD 阴性血源和合理运用 RhD 阴性血液有重要意义,为该地区尤其蒙古族 RhD 阴性血型积累了资料。

  18. A study on scar revision

    OpenAIRE

    Ashutosh Talwar; Neerja Puri

    2016-01-01

    Introduction: Scars are psychologically distressing for the patients and have an impact on the quality of life and self esteem of the patients. Scar revision is an aesthetic skill which is mastered by plastic surgeons and encroached now by dermatosurgeons. Scars on the face are aesthetically unacceptable and various techniques have been improvised for making a scar aesthetically acceptable. Various types of techniques are used for scar revision like W plasty, Z plasty and VY plasty. Aims:...

  19. Blood Clots

    Science.gov (United States)

    ... or prevent blood clots from dissolving properly. Risk factors for excessive blood clotting include Certain genetic disorders Atherosclerosis Diabetes Atrial fibrillation Overweight, obesity, and metabolic syndrome Some medicines Smoking deep vein ...

  20. Blood Transfusion

    Science.gov (United States)

    ... to their work or home. The availability of plastic bags that can have one or more satellite bags ... in preparing the donated blood. The use of plastic bags allows the blood center to make a variety ...

  1. Blood Facts and Statistics

    Science.gov (United States)

    ... Facts and Statistics Printable Version Blood Facts and Statistics Facts about blood needs Facts about the blood ... to Top Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells ...

  2. Establishment Registration & Device Listing

    Data.gov (United States)

    U.S. Department of Health & Human Services — This searchable database contains establishments (engaged in the manufacture, preparation, propagation, compounding, assembly, or processing of medical devices...

  3. Establishment of Rabbit Model of Sick Sinus Syndrome Combined with Heart-yang Deficiency and Blood Stasis Syndrome%慢性病态窦房结综合征与心阳虚血瘀病证结合模型研究

    Institute of Scientific and Technical Information of China (English)

    李汇博; 刘如秀; 王妮娜; 暴美静; 汪艳丽

    2011-01-01

    Objective To explore the feasibility to establish a rabbit model of sick sinus syndrome combined with heart-yang deficiency and blood stasis syndrome (short as combined model) via surgery.Methods The TCM syndrome model was established by the method of ice wetting, cold stimulation and subcutaneous injection with adrenaline hydrochloride, and the combined model was established by damaging the sinoatrial node with 20% formaldehyde. The general state, body temperature, respiratory frequency, heart rate and rhythm, swimming distance and speed in 6 min, and hemorheology indexes were observed before and after the model of each group established. The TCM syndrome characteristics of the two models were compared according to the clinical diagnostic standard of yang deficiency and blood stasis syndrome. Results After the modle established, rabbits of both groups had lower temperature, higher respiratory frequency and heart rate, lower swimming distance and speed, and higher hemorheology indexes. There were no difference between the two groups in the indexes as mentioned except the heart rate, swimming distance and speed. Conclusion The combined model established by surgery has no difference with the TCM syndrome model in syndrome featrues, and it conforms to the clinical diagnostic standard of yang deficiency and blood stasis syndrome.%目的 探讨手术方法建立病态窦房结综合征(以下简称"病窦综合征")与心阳虚血瘀病证结合模型的可行性.方法 采取冰敷、置于寒冷环境、皮下注射肾上腺素的方法制备非疾病阳虚血瘀证候模型;以2 0%甲醛注射浸润窦房结区建立慢性病窦综合征阳虚血瘀病证结合模型,观察2组兔造模前后一般情况、体温、呼吸频率、心率、心律、6 min游泳时间及速率、血液流变学(全血黏度、血浆黏度、红细胞聚集指数)等指标,根据中医临床阳虚血瘀证的诊断标准,对2种模型的中医证候特点进行比较.结果 2组免造

  4. 前列腺增生症肾虚血瘀证大鼠动物模型的建立与评价%Establishment and evaluation of benign prostatic hyperplasia in rats with deficiency of kidney and blood stasis animal model

    Institute of Scientific and Technical Information of China (English)

    樊新荣; 颜苗; 何清湖

    2013-01-01

    Objectives:To establish and evaluate benign prostate hyperplasia rat animal model with blood stasis due to kidney deficiency. Methods;Using the castration surgery, hormone injections and ice bath method manufacturing BPH with kidney deficiency and blood stasis rat model j this paper investigated the prostate wet weight, prostate index and the content of serum prostate specific acid phosphatase (PAP) , and observed model rats pathological tissue morphology. Results; The whole blood viscosity, plasma viscosity, erythrocyte gathered index and Casson viscosity of rats in model group were significantly higher than that in blank group and sham-operated group, and the difference was statistically significant (P < 0. 05). The content of serum PAP in model group was increased (P < 0. 05 ) , and prostate tissue had been observed visible small blood vessels and congestion, according with blood stasis, thus it is demonstrated that the blood stasis rats model had been done. Conclusions; The rat model for BPH witk kidney deficiency and blood stasis was copied successfully. Production method is simple and the evaluation index is objective, which provides the good experimental foundation and theoretical basis for the study of BPH with kidney deficiency and blood stasis syndrome and the theraputic mechanism of related Traditional Chinese Medicine.%目的:建立前列腺增生症(BPH)肾虚血瘀证大鼠动物模型并进行评价.方法:采用去势手术、激素注射加冰浴方法制作BPH肾虚血瘀证大鼠模型,考察前列腺湿重、前列腺指数和血清前列腺特异性酸性磷酸酶(PAP)含量,观察模型大鼠病理组织形态学.结果:模型组大鼠全血黏度、血浆黏度、红细胞聚集指数和卡松黏度均明显高于空白组和假手术组(P<0.05);模型组血清PAP的含量升高(P<0.05),并且模型组大鼠前列腺组织病理组织学观察可见小血管扩张、充血,符合瘀血的病理表现.结论:该模型制作方法简单,

  5. 妊娠期女性血细胞主要参数生物参考区间建立的初步探讨%Preliminary investigation on the establishment of biological reference intervals about the main parameters of blood cells among pregnant women

    Institute of Scientific and Technical Information of China (English)

    葛雅芳; 沈云岳; 唐振华

    2014-01-01

    目的:建立本实验室妊娠期女性血细胞主要参数的生物参考区间。方法选取331例正常足月分娩的孕妇,追溯其孕期检查记录,用 SAS 8.1软件对孕期间进行的2次血细胞常规检测结果进行统计分析,获得参考区间。结果比较妊娠早期和妊娠晚期的各项血常规检验结果,差异具有统计学意义(P 均<0.05)。参考区间分析显示血小板(PLT)、单核细胞百分比(M %)和嗜碱性粒细胞百分比(B %)检验结果均在现行参考区间内,故继续沿用原有参考区间;血细胞比容(HCT)和嗜酸性粒细胞百分比(E %)检验结果,经验证可合并参考区间;而红细胞计数(RBC)、血红蛋白(Hb)、白细胞计数(WBC)、中性粒细胞百分比(N %)及淋巴细胞百分比(L%)需分组建立不同的参考区间。结论新建的生物参考区间更符合孕期的生理变化,能更好的指导临床诊断和治疗。%Objective To establish the biological reference intervals about the main parameters of blood cells among pregnant women in our laboratory.Methods A total of 331 pregnant women who had normal and term delivery were enrolled.According to their medical records,their 2 reports of pregnancy routine blood cell tests were obtained. The results were analyzed statistically,and the biological reference intervals were calculated by SAS 8.1 software. Results There was statistical significance in all parameters of pregnancy routine blood cell tests between the first and third trimesters (P <0.05).The results of biological reference intervals showed that the 2 sets of data about platelet (PLT),monocyte percentage (M%)and basophilic granulocyte percentage (B %)were all within current biological reference intervals,then the current biological reference intervals could be used for pregnancy.The 2 sets of data about hematocrit (HCT)and eosinophile granulocyte percentage (E %)could be combined to

  6. Establishment and Characterization of a Newly Established Diabetic Gerbil Line.

    Directory of Open Access Journals (Sweden)

    Xiaohong Li

    Full Text Available We aimed to selectively breed a spontaneous diabetic gerbil when a sub-line of inbred gerbil showed increased blood glucose levels was found recently. Then we investigated the characteristics including the serum insulin, triglyceride, cholesterol, leptin, adiponectin and explored the underlying molecular mechanism for the diabetic phenotype.The spontaneous diabetic line of gerbils was selectively inbreed the sub-line of gerbil by monitoring blood glucose of each animal. The serum insulin, adiponectin, and leptin levels were tested using an ELISA kit. The expression levels of GLUT4, Akt, leptin, adiponectin, and calpain 10 (CAPN10 were tested by western blot and Quantitative Real-time PCR (qPCR in liver, skeletal muscle, and white adipose.Our results show that the percentages of animals with FPG≥5.2 (mmol/l, PG2h≥6.8 (mmol/l and both FPG≥5.2 and PG2h≥6.8 (mmol/l were increased with the number of breeding generations from F0 (21.33% to F6 (38.46%. These diabetic gerbils exhibited insulin resistance and leptin resistance as well as decreased adiponectin level in the serum. We also observed decreased expression of adiponectin and increased expression of leptin in the skeletal muscle, respectively.These results indicate that we have primarily established a spontaneous diabetic gerbil line, and the diabetic phenotypes may have been accounted for by altered expression of leptin and adiponectin.

  7. Alendronate treatment in the revision setting, with and without controlled implant motion

    DEFF Research Database (Denmark)

    Søballe, Kjeld; Chen, Xinqian; Jensen, Thomas B;

    2007-01-01

    . The other half of the implants continued pistoning. Half of the dogs were exposed to alendronate (oral). Results Stabilization of the revision implant was more effective at improving fixation (higher shear strength) than administering alendronate. As expected, the fibrous membrane remained under unstable...... model with controlled motion to evaluate the relative effects of implant motion and bisphosphonate. We implemented our established 8-week experimental revision protocol to obtain a bony and soft tissue setting of revision joint replacement in 16 dogs. At 8 weeks, we had stabilized half of the implants...

  8. 2009 review and revisions of the international standards for the neurological classification of spinal cord injury

    DEFF Research Database (Denmark)

    Waring, William P; Biering-Sorensen, Fin; Burns, Stephen;

    2010-01-01

    of the ISNCSCI. The Standards Committee also noted that, although the 2008 reprint pocket booklet is current, the reference manual should be revised after proposals to modify/revise the ASIA Impairment Scale (AIS as modified from Frankel) are considered. In addition, the Standards Committee adopted a process...... were also reviewed. The last citable reference for the ISNCSCI's methodology is the ISNCSCI Reference Manual, published in 2003 by ASIA. The Standards Committee recommended that the numerous items that were revised should be published and a precedent established for a routine published review...

  9. Program distribution for unclassified scientific and technical reports: Instructions and category scope notes: Revision 75

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, W.F. Jr.; Amburn, D. (eds.)

    1989-08-01

    The DOE Office of Scientific and Technical Information (OSTI) in conjunction with DOE Program Offices establishes distribution categories for research, development, and technological reports emanating from DOE programs. The revised category numbers and scope notes contained in this publication were coordinated between OSTI and DOE Program Offices with input from DOE Field Offices. Decisions regarding whether reports will be distributed are made by Program Offices in conjunction with DOE Field Offices and OSTI. This revision of DOE/OSTI-4500 contains the revised distribution category numbers and scope notes along with the printed copy requirement, which shows the number of copies required to make program distribution.

  10. Immunoelectrophoresis - blood

    Science.gov (United States)

    IEP - serum; Immunoglobulin electrophoresis - blood; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis; Amyloidosis - electrophoresis serum; Multiple myeloma - serum electrophoresis; Waldenström - serum electrophoresis

  11. Engineering drawing field verification program. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Ulk, P.F.

    1994-10-12

    Safe, efficient operation of waste tank farm facilities is dependent in part upon the availability of accurate, up-to-date plant drawings. Accurate plant drawings are also required in support of facility upgrades and future engineering remediation projects. This supporting document establishes the procedure for performing a visual field verification of engineering drawings, the degree of visual observation being performed and documenting the results. A copy of the drawing attesting to the degree of visual observation will be paginated into the released Engineering Change Notice (ECN) documenting the field verification for future retrieval and reference. All waste tank farm essential and support drawings within the scope of this program will be converted from manual to computer aided drafting (CAD) drawings. A permanent reference to the field verification status will be placed along the right border of the CAD-converted drawing, referencing the revision level, at which the visual verification was performed and documented.

  12. Local public document room directory. Revision 7

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This directory (NUREG/BR-0088, Revision 7) lists local public document rooms (LPDRs) for commercial nuclear power plants with operating or possession-only licenses or under construction, plus the LPDRs for potential high-level radioactive waste repository sites, gaseous diffusion plants, certain fuel cycle facilities, certain low-level waste disposal facilities, and any temporary LPDRs established for the duration of licensing proceedings. In some instances, the LPDR libraries maintain document collections for more than one licensed facility. The library staff members listed are the persons most familiar with the LPDR collections. Reference librarians in the NRC Headquarters Public Document Room (PDR) are also available to assist the public in locating NRC documents.

  13. Quality Management, Quality Assurance and Quality Control in Blood Establishments

    OpenAIRE

    Bolbate, N

    2008-01-01

    Quality terms and the roots of the matter are analyzed according to European Committee’s recommendations. Essence of process and product quality control as well as essence of quality assurance is described. Quality system’s structure including quality control, quality assurance and management is justified in the article.

  14. Medical writing, revising and editing

    DEFF Research Database (Denmark)

    Pilegaard, Morten

    2006-01-01

    The globalization of science makes medical writing, editing and revision a rapidly growing field of linguistic study and practice. Medical science texts are written according to uniform, general guidelines and medical genres have become highly conventionalized in terms of structure and linguistic...... form. Medical editing often takes the form of peer review and mainly addresses issues of contents and overall validity. Medical revision incorporates the checking of the macrostructure and the microstructure of the text, its language and style and its suitability for the target reader or client...

  15. Quantum interaction. Revised selected papers

    Energy Technology Data Exchange (ETDEWEB)

    Song, Dawei; Zhang, Peng; Wang, Lei [Aberdeen Univ. (United Kingdom). School of Computing; Melucci, Massimo [Padua Univ., Padova (Italy). Dept. of Information Engineering; Frommholz, Ingo [Bedfordshire Univ. (United Kingdom); Arafat, Sachi (eds.) [Glasgow Univ. (United Kingdom). School of Computing Science

    2011-07-01

    This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Symposium on Quantum Interaction, QI 2011, held in Aberdeen, UK, in June 2011. The 26 revised full papers and 6 revised poster papers, presented together with 1 tutorial and 1 invited talk were carefully reviewed and selected from numerous submissions during two rounds of reviewing and improvement. The papers show the cross-disciplinary nature of quantum interaction covering topics such as computation, cognition, mechanics, social interaction, semantic space and information representation and retrieval. (orig.)

  16. Understanding Blood Counts

    Science.gov (United States)

    ... Lab and Imaging Tests Understanding Blood Counts Understanding Blood Counts Understanding Blood Counts SHARE: Print Glossary Blood cell counts give ... your blood that's occupied by red cells. Normal Blood Counts Normal blood counts fall within a range ...

  17. Establishment and Application of a Noninvasive Method for Estimation of Total Haemoglobin Content in Red Blood Cell Components%非侵入性评估红细胞成分血中血红蛋白总量方法的建立及应用

    Institute of Scientific and Technical Information of China (English)

    伍伟健; 黄敏桃; 罗媚佳; 庞晓丹; 余晋林

    2012-01-01

    Objective To establish and apply a noninvasive method for estimation of total hemoglobin (Hb)content in red blood cell components to improve the level of standardization of transfusion.Methods Two hundred and thirty leukocyte-reduced red blood cells were elected as research objects,which were randomly selected in stock bloods of Foshan Blood Station.The weight,volume and Hb concentration of one hundred and thirty red blood cell components were tested.The correlation between Hb content with weight of red blood cell components was analyzed.A linear regression model was used to assess the relationship.Regression equation was built. One hundred red blood cell components were tested and analysed by the regression equation.The results were compared with the actual detection value in order to verify the reliability of the method we built. Results There was a positive correlativity of the weight and Hb concentration of red blood cell components(r=0.971,P<0.001) ;The regression equation was y=0.1913x-2.9373,y was Hb concentration,x was weight of red blood cell components.Linear regression analysis results showed that the weight was closely related to Hb concentration of red blood cell components.Partial regression value(b)was -2.9373 and 0.1913(r2 =0.944,df=128,F=2138.12;P<0.01).The estimation of total Hb content in one hundred red blood cell components showed that the assessment and the actual results were no significant differences(P>0.05).Conclusions The noninvasive method for estimation of total Hb content in red blood cell components was simple,safe,reliable and contributed to improve the level of standardization of transfusion. But it need to be confirmed by a multi-center and large sample and randomized controlled research before popularization in transfusion.%目的 探讨建立并应用一种非侵入性准确评估红细胞成分血中血红蛋白(Hb)总量的方法,以提高临床输血标准化水平.方法 自本血站库存血液中,随机抽取230袋

  18. Revision of failed humeral head resurfacing arthroplasty

    Directory of Open Access Journals (Sweden)

    Philipp N Streubel

    2016-01-01

    Conclusion: Outcomes of revision of HHR arthroplasty in this cohort did not improve upon those reported for revision of stemmed humeral implants. A comparative study would be required to allow for definitive conclusions to be made.

  19. Diet History Questionnaire: Database Revision History

    Science.gov (United States)

    The following details all additions and revisions made to the DHQ nutrient and food database. This revision history is provided as a reference for investigators who may have performed analyses with a previous release of the database.

  20. BLOOD DONATION

    CERN Multimedia

    SC Unit

    2008-01-01

    A blood donation, organized by EFS (Etablissement Français du Sang) of Annemasse will take place On Wednesday 12 November 2008, from 8:30 to 16:00, at CERN Restaurant 2 If possible, please, bring your blood group Card.

  1. Blood donation

    CERN Multimedia

    GS Department

    2009-01-01

    A blood donation is organised by the Cantonal Hospital of Geneva On Thursday 19 March 2009 from 9 a.m. to 5 p.m. CERN RESTAURANT 2 Number of donations during the last blood donations :135 donors in July 2008 122 donors in November 2008 Let’s do better in 2009 !!! Give 30 minutes of your time to save lives...

  2. Soft tissue trauma and scar revision.

    Science.gov (United States)

    Mobley, Steven R; Sjogren, Phayvanh P

    2014-11-01

    Numerous techniques and treatments have been described for scar revision, with most studies focusing on the adult population. A comprehensive review of the literature reveals a paucity of references related specifically to scar revision in children. This review describes the available modalities in pediatric facial scar revision. The authors have integrated current practices in soft tissue trauma and scar revision, including closure techniques and materials, topical therapy, steroid injection, cutaneous laser therapy, and tissue expanders.

  3. A Practical Propositional Knowledge Base Revision Algorithm

    Institute of Scientific and Technical Information of China (English)

    陶雪红; 孙伟; 等

    1997-01-01

    This paper gives an outline of knowledge base revision and some recently presented complexity results about propostitional knowledge base revision.Different methods for revising propositional knowledge base have been proposed recently by several researchers,but all methods are intractable in the general case.For practical application,this paper presents a revision method for special case,and gives its corresponding polynomial algorithm.

  4. Tainted blood

    DEFF Research Database (Denmark)

    Deleuran, Ida; Sheikh, Zainab Afshan; Hoeyer, Klaus

    2015-01-01

    study of the historical rise and current workings of safety practices in the Danish blood system. Here, we identify a strong focus on contamination in order to avoid 'tainted blood', at the expense of working with risks that could be avoided through enhanced blood monitoring practices. Of further...... significance to this focus are the social dynamics found at the heart of safety practices aimed at avoiding contamination. We argue that such dynamics need more attention, in order to achieve good health outcomes in transfusion medicine. Thus, we conclude that, to ensure continuously safe blood systems, we...... need to move beyond the bifurcation of the social and medical aspects of blood supply as two separate issues and approach social dynamics as key medical safety questions....

  5. 78 FR 13069 - Draft Guidance for Industry: Recommendations for Screening, Testing, and, Management of Blood...

    Science.gov (United States)

    2013-02-26

    ...The Food and Drug Administration (FDA) is announcing the availability of a draft document entitled ``Guidance for Industry: Recommendations for Screening, Testing, and Management of Blood Donors and Blood and Blood Components Based on Screening Tests for Syphilis,'' dated March 2013. The draft guidance document provides revised recommendations for screening and testing of donors and management......

  6. Humeral windows in revision total elbow arthroplasty

    Science.gov (United States)

    Salama, Amir; Stanley, David

    2016-01-01

    The use of cortical windows for revision elbow arthroplasty has not previously been widely reported. Their use aids safe revision of a well fixed humeral prosthesis and can be used in the setting of dislocation, periprosthetic fracture or aseptic loosening of the ulnar component. We describe our technique and results of cortical windows in the distal humerus for revision elbow arthroplasty surgery. PMID:27583011

  7. Revising Psychiatry's Charter Document: "DSM-IV."

    Science.gov (United States)

    McCarthy, Lucille Parkinson; Gerring, Joan Page

    1994-01-01

    Reports findings from a three-year study by a composition researcher and a psychiatrist of the revision of an important mental health book: "Diagnostic and Statistical Manual of Mental Disorders." Examines the revision using three methodologies. Concludes that the revision functions to achieve certain social and political effects. (HB)

  8. A taxonomic revision of the genus Podocarpus

    NARCIS (Netherlands)

    Laubenfels, de D.J.

    1985-01-01

    In connection with the forthcoming revision of the Coniferae for the Flora Malesiana, the author thought it necessary to revise the genus Podocarpus. Although this genus has a substantial representation in Malesia (30 species), the revision is too involved to be appropriate with the Flora Malesiana

  9. What Happens to Donated Blood?

    Science.gov (United States)

    ... week. Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells Platelets Plasma ... About Blood Blood Facts and Statistics Blood Types Blood Components What Happens to Donated Blood Blood and Diversity ...

  10. Revised hypothesis and future perspectives

    DEFF Research Database (Denmark)

    Norsk, P; Drummer, C; Christensen, N J

    2001-01-01

    Results from space have been unexpected and not predictable from the results of ground-based simulations. Therefore, the concept of how weightlessness and gravity modulates the regulation of body fluids must be revised and a new simulation model developed. The main questions to ask in the future ...

  11. Revised Accounting for Business Combinations

    Science.gov (United States)

    Wilson, Arlette C.; Key, Kimberly

    2008-01-01

    The Financial Accounting Standards Board (FASB) has recently issued Statement of Financial Accounting Standards No. 141 (Revised 2007) Business Combinations. The object of this Statement is to improve the relevance, representational faithfulness, and comparability of reported information about a business combination and its effects. This Statement…

  12. Curriculum revision and ICT integration

    OpenAIRE

    Atanasova-Pacemska, Tatjana

    2006-01-01

    In this paper we will present the possibilities for revision and development of the curriculum of "Math Teaching Methods" related to Child-centered methodology and ICT integration. This paper is a result of the projects: "Teacher, Technology and young learners" and "Child-centered methodology" supported by USAID and World Learning.

  13. Revision of Drymophloeus (Areceacea: Arecoideae)

    NARCIS (Netherlands)

    Zona, Scott

    1999-01-01

    A revision of the genus Drymophloeus (Arecaceae: Arecoideae: Ptychospermatinae) recognizes seven species, distributed from the Maluku Islands of Indonesia to Western Samoa. The history of the genus is reviewed. A key, species descriptions, a complete list of synonymy, a list of specimens examined, i

  14. A revision of Ichnocarpus (Apocynaceae)

    NARCIS (Netherlands)

    Middleton, D.J.

    1994-01-01

    The genus Ichnocarpus is revised. A total of 12 species are recognised, of which one new species is described. Three new combinations in Ichnocarpus and one in Anodendron are made. Micrechites and Lamechites are treated as synonyms of Ichnocarpus. Nomina nuda and species exclusae have been given as

  15. Ethical considerations in revision rhinoplasty.

    Science.gov (United States)

    Wayne, Ivan

    2012-08-01

    The problems that arise when reviewing another surgeon's work, the financial aspects of revision surgery, and the controversies that present in marketing and advertising will be explored. The technological advances of computer imaging and the Internet have introduced new problems that require our additional consideration.

  16. Air Pollution Primer. Revised Education.

    Science.gov (United States)

    Corman, Rena

    This revised and updated book is written to inform the citizens on the nature, causes, and effects of air pollution. It is written in terms familiar to the layman with the purpose of providing knowledge and motivation to spur community action on clean air policies. Numerous charts and drawings are provided to support discussion of air pollution…

  17. Revised Safety Code A2

    CERN Multimedia

    SC Secretariat

    2005-01-01

    Please note that the revised Safety Code A2 (Code A2 rev.) entitled "REPORTING OF ACCIDENTS AND NEAR MISSES" is available on the web at the following url: https://edms.cern.ch/document/335502/LAST_RELEASED Paper copies can also be obtained from the SC Unit Secretariat, e-mail: sc.secretariat@cern.ch SC Secretariat

  18. REVISION MASTOIDECTOMY AND ITS GOAL

    Directory of Open Access Journals (Sweden)

    Sampath Kumar Singh Katewad

    2016-06-01

    Full Text Available BACKGROUND The main aims in doing surgery for chronic otitis media are: 1. Complete clearance of progressive disease from its site and form dry and well-epithelialised cavity. 2. Prevention of recurrent and residual cholesteatoma achieved by modifying the anatomy of tympanomastoid compartments. 3. Hearing improvement by reconstructing the ossicles and tympanic membrane. The main indication for revision surgery is failure to achieve above said aims by previous surgeon. The aim of our study was to identify the causes of recurrent disease and the factors that helps in chronic otitis media surgery to minimise the revisions & report the results of revision mastoidectomy. MATERIALS AND METHODS In this study, thirty patients are selected and operated for revision mastoidectomy surgery at our institute during the period from May 2013 – Dec 2015. These cases were analysed retrospectively, patients who had discharging ear with the history of previous intact canal wall and canal down mastoidectomy surgeries were selected for this study. OBSERVATION AND RESULTS In this study, the common age group of patients who underwent revision surgery - 8-46 yrs. (mean 19 yrs.. Majority of patients are female, 16 cases (53.33%; and males 14 cases (46.66%. Revision mastoidectomies were applied to 12 cases (40% of previous canal wall up mastoidectomies and 18 cases (60% of prior canal down mastoidectomies. 60% of cases had residual/recurrent cholesteatoma which was the most common finding seen. While in 33.3% cases patient had only chronic granulations. The most frequent site of cholesteatoma was mastoid antrum/mastoid cavity seen in 73% followed by attic 42.3% and mesotympanum in 40% of cases. The common failure in primary surgery was inadequate clearance of diseased mastoid air cells - 48%, high facial bridge - 48%, stenotic meatoplasty - 40%, incomplete removal of buttress - 30%. Tympanic membrane perforation - 6.66% of cases with poor architecture of mastoidectomy

  19. Secular Religious Establishment

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2013-01-01

    Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer to the co......Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer...... to the compatibility question is not obvious and requires a systematic analysis of secularism. Based on a distinction between a general concept and specific conceptions of secularism I offer a general structure for conceptions of secularism that incorporates both a) basic values, e.g. political equality and freedom...... of secularism are therefore compatible with some forms of religious establishment. I illustrate the use of the framework for discussion of particular establishment cases and how the framework provides a structure for the normative discussion about which conception of secularism to accept....

  20. Storing Blood Cells

    Science.gov (United States)

    1976-01-01

    The National Cancer Institute worked with Goddard Space Flight Center to propose a solution to the blood-cell freezing problem. White blood cells and bone marrow are stored for future use by leukemia patients as a result of Goddard and Jet Propulsion Laboratory expertise in electronics and cryogenics. White blood cell and bone marrow bank established using freezing unit. Freezing unit monitors temperature of cells themselves. Thermocouple placed against polyethylene container relays temperature signals to an electronic system which controls small heaters located outside container. Heaters allow liquid nitrogen to circulate at constant temperature and maintain consistent freezing rate. Ability to freeze, store, and thaw white cells and bone marrow without damage is important in leukemia treatment.

  1. Blood Typing

    Science.gov (United States)

    ... if you need repeated transfusions, as sickle cell anemia and thalassemia patients do. If blood transfusions are not closely ... the News Article Index About This Site Send Us Your Comments For ...

  2. Blood Disorders

    Science.gov (United States)

    ... people with blood disorders. Magnitude of the Problem Complications from deep vein thrombosis (DVT) kill more people each year than breast cancer, motor vehicle accidents, and HIV combined. Sickle cell trait ...

  3. What's Blood?

    Science.gov (United States)

    ... Rh" because scientists found it while studying Rhesus monkeys. If your blood is positive, you have this ... doctor. © 1995- The Nemours Foundation. All rights reserved. Images provided by The Nemours Foundation, iStock, Getty Images, ...

  4. Artificial blood.

    OpenAIRE

    1983-01-01

    #Blood substitutes have been developed for almost a century. The various type of artificial blood was continuously available on the market. The theme of this report is to identify the best substitute in emergency situation for some patients and science students. The definition of best is given; thus, as the vital part of the report, the comparison between them is described and discussed. Modified hemoglobin, bovine-based hemoglobin and PFCs are three basic types. In terms of the perfor...

  5. Blood Transfusion and Donation

    Science.gov (United States)

    ... receiving the blood transfusion. To keep blood safe, blood banks carefully screen donated blood. The risk of catching ... one or more times before the surgery. A blood bank will store your blood for your use. NIH: ...

  6. Blood (For Parents)

    Science.gov (United States)

    ... Old Feeding Your 1- to 2-Year-Old Blood KidsHealth > For Parents > Blood A A A What's ... about the mysterious, life-sustaining fluid called blood. Blood Basics Two types of blood vessels carry blood ...

  7. Catecholamine blood test

    Science.gov (United States)

    Norepinephrine -- blood; Epinephrine -- blood; Adrenalin -- blood; Dopamine -- blood ... A blood sample is needed. ... the test. This is especially true if both blood and urine catecholamines are to be measured. You ...

  8. Biology of Blood

    Science.gov (United States)

    ... here for the Professional Version Home Blood Disorders Biology of Blood Overview of Blood Resources In This ... Version. DOCTORS: Click here for the Professional Version Biology of Blood Overview of Blood Components of Blood ...

  9. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... Blood Basics Blood Disorders Anemia Bleeding Disorders Blood Cancers Blood Clots Blood Clotting and Pregnancy Clots and ... Increased maternal age Other medical illness (e.g., cancer, infection) back to top How are Blood Clots ...

  10. Belief Revision and Argumentation Theory

    Science.gov (United States)

    Falappa, Marcelo Alejandro; Kern-Isberner, Gabriele; Simari, Guillermo Ricardo

    Belief revision is the process of changing beliefs to adapt the epistemic state of an agent to a new piece of information. The logical formalization of belief revision is a topic of research in philosophy, logic, and in computer science, in areas such as databases or artificial intelligence. On the other hand, argumentation is concerned primarily with the evaluation of claims based on premises in order to reach conclusions. Both provide basic and substantial techniques for the art of reasoning, as it is performed by human beings in everyday life situations and which goes far beyond logical deduction. Reasoning, in this sense, makes possible to deal successfully with problems in uncertain, dynamic environments and has been promoting the development of human societies.

  11. Blood and war.

    Science.gov (United States)

    Hedley-Whyte, John; Milamed, Debra R

    2010-09-01

    In 1894 Ulsterman and pathologist Almroth Wright described the citation of blood. Twenty-one years later it was introduced into wartime and clinical practice. Harvard Medical School had a large part in providing Colonel Andrew Fullerton, later Professor of Surgery, Queen's Belfast, with the intellectual and practical help for the Allies to deploy blood on the post-Somme Western Front and in Salonika. The key investigators and clinicians were Americans and Canadians who with Fullerton and Wright instructed the Allies. The key enablers were two Harvard-trained surgeons surnamed Robertson-Oswald H. ("Robby") and L. Bruce (no relation). Physician Roger I. Lee of Harvard, surgeon George W Crile of Cleveland, Peyton Rous of the Rockefeller Institute and Richard Lewisohn of Mount Sinai Hospital, both located in the Upper East Side of New York City, played key roles.By Armistice in 1918, indirect citrated nutrient-enhanced blood transfusion was widely used by the Allies. Geoffrey Keynes was taught the techniques of blood transfusion by Dr. Benjamin Harrison Alton of Harvard at a Casualty Clearing Station near Albert at the time of the Battle of Passchendaele. Professor "Robby" Robertson, DSO, Sir Geoffrey Keynes and Sir Thomas Houston established blood banking.

  12. Managing your blood sugar

    Science.gov (United States)

    Hyperglycemia - control; Hypoglycemia - control; Diabetes - blood sugar control; Blood glucose - managing ... Know how to: Recognize and treat low blood sugar (hypoglycemia) Recognize and treat high blood sugar (hyperglycemia) ...

  13. Clean Air Act. Revision 5

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-15

    This Reference Book contains a current copy of the Clean Air Act, as amended, and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. This Reference Book has been completely revised and is current through February 15, 1994.

  14. Non-Power Reactor Operator Licensing Examiner Standards. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    The Non-Power Reactor Operator Licensing Examiner Standards provide policy and guidance to NRC examiners and establish the procedures and practices for examining and licensing of applicants for NRC operator licenses pursuant to Part 55 of Title 10 of the Code of Federal Regulations (10 CFR 55). They are intended to assist NRC examiners and facility licensees to understand the examination process better and to provide for equitable and consistent administration of examinations to all applicants by NRC examiners. These standards are not a substitute for the operator licensing regulations and are subject to revision or other internal operator examination licensing policy changes. As appropriate, these standards will be revised periodically to accommodate comments and reflect new information or experience.

  15. The Revised Bloom's Taxonomy: implications for educating nurses.

    Science.gov (United States)

    Su, Whei Ming; Osisek, Paul J

    2011-07-01

    One of the essential goals for continuing education in nursing is to enhance nurses' ability to improve patient care outcomes. Toward this goal, learners need to transfer learned knowledge to actual practice. Achieving effective transfer requires knowledge of thinking paradigms in relation to specific subject content. Educators can facilitate knowledge transfer by developing instructional designs that incorporate subject content and cognitive processes related to the use of the subject content. However, it is difficult to develop such instructional designs. The Revised Bloom's Taxonomy provides a framework for meeting this educational need. In this article, the authors establish the relevance of the Revised Bloom's Taxonomy to continuing education and describe how to use the taxonomy to plan an educational session with an emphasis on promoting knowledge transfer.

  16. Revision of hip resurfacing arthroplasty.

    Science.gov (United States)

    Wera, Glenn D; Gillespie, Robert J; Petty, Carter; Petersilge, William J; Kraay, Matthew J; Goldberg, Victor M

    2010-08-01

    Metal-on-metal (MOM) hip resurfacing has become an increasingly popular treatment for young, active patients with degenerative disease of the hip, as bearing surfaces with better wear properties are now available. One proposed advantage of resurfacing is its ability to be successfully revised to total hip arthroplasty (THA). In addition, radiographic parameters that may predict failure in hip resurfacing have yet to be clearly defined. Seven MOM resurfacing arthroplasties were converted to conventional THAs because of aseptic failure. Using Harris Hip Scores (HHS) and Short Form 12 (SF-12) questionnaire scores, we compared the clinical outcomes of these patients with those of patients who underwent uncomplicated MOM hip resurfacing. In addition, all revisions were radiographically evaluated. Mean follow-up periods were 51 months (revision group) and 43 months (control group). There was no significant difference between the 2 groups' HHS or SF-12 scores. There was no dislocation or aseptic loosening after conversion of any resurfacing arthroplasty. Valgus neck-shaft angle (P hip resurfacing. Conversion of aseptic failure of hip resurfacing to conventional THA leads to clinical outcomes similar to those of patients who undergo uncomplicated hip resurfacing. The orientation of the femur and the components placed play a large role in implant survival in hip resurfacing. More work needs to be done to further elucidate these radiographic parameters.

  17. Iron deficiency in blood donors

    Directory of Open Access Journals (Sweden)

    Armando Cortés

    2005-03-01

    Full Text Available Context: Blood donation results in a substantial loss of iron (200 to 250 mg at each bleeding procedure (425 to 475 ml and subsequent mobilization of iron from body stores. Recent reports have shown that body iron reserves generally are small and iron depletion is more frequent in blood donors than in non-donors. Objective: The aim of this study was to evaluate the frequency of iron deficiency in blood donors and to establish the frequency of iron deficiency in blood donors according to sex, whether they were first-time or multi-time donors. Design: From march 20 to April 5, 2004, three hundred potential blood donors from Hemocentro del Café y Tolima Grande were studied. Diagnostic tests: Using a combination of biochemical measurements of iron status: serum ferritin (RIA, ANNAR and the hemoglobin pre and post-donation (HEMOCUE Vital technology medical . Results: The frequency of iron deficiency in potential blood donors was 5%, and blood donors accepted was 5.1%; in blood donors rejected for low hemoglobin the frequency of iron deficiency was 3.7% and accepted blood donors was 1.7% in male and 12.6% in female. The frequency of iron deficiency was higher in multi-time blood donors than in first-time blood donors, but not stadistic significative. Increase nivel accepted hemoglobina in 1 g/dl no incidence in male; in female increase of 0.5 g/dl low in 25% blood donors accepted with iron deficiency, but increased rejected innecesary in 16.6% and increased is 1 g/dl low blood donors female accepted in 58% (7/12, but increased the rejected innecesary in 35.6%. Conclusions: We conclude that blood donation not is a important factor for iron deficiency in blood donors. The high frequency of blood donors with iron deficiency found in this study suggests a need for a more accurate laboratory trial, as hemoglobin or hematocrit measurement alone is not sufficient for detecting and excluding blood donors with iron deficiency without anemia, and ajustes hacia

  18. Nomenclatural corrections to the taxonomic revision of The Old World species of Boehmeria (Urticaceae, tribus Boehmeriae) by Wilmot-Dear and Friis (2013)

    DEFF Research Database (Denmark)

    Wilmot-Dear, Christine Melanie; Friis, Ib; Govaerts, R. H. A.

    2014-01-01

    This nomenclatural note, a sequel to a recently published taxonomic revision of the Old World species of the genus Boehmeria (Urticaceae), establishes: (1) a holotype of B. maugeretii, synonym of taxon no. 8b in the revision (B. clidemioides var. diffusa), (2) B. 15 zollingeriana Wedd. var. blini...

  19. Nomenclatural corrections to the taxonomic revision of The Old World species of Boehmeria (Urticaceae, tribus Boehmerieae) by Wilmot-Dear & Friis

    NARCIS (Netherlands)

    Wilmot-Dear, C.M.; Friis, I.; Govaerts, R.H.A.

    2014-01-01

    This nomenclatural note, a sequel to a recently published taxonomic revision of the Old World species of the genus Boehmeria (Urticaceae), establishes: 1) a holotype of B. maugereti, synonym of taxon no. 8b in the revision (B. clidemioides var. diffusa); 2) B. zollingeriana Wedd. var. blinii (H.Lév.

  20. Blood Basics

    Science.gov (United States)

    ... of ASH ASH Meeting on Hematologic Malignancies Consultative Hematology Course ASH Meeting on Lymphoma Biology ASH Workshop on Genome Editing Publications Blood The Hematologist ASH Clinical News ASH Self-Assessment Program Hematology , ASH Education Program About Awards Membership ASH Foundation ...

  1. Blood Clots

    Science.gov (United States)

    ... of ASH ASH Meeting on Hematologic Malignancies Consultative Hematology Course ASH Meeting on Lymphoma Biology ASH Workshop on Genome Editing Publications Blood The Hematologist ASH Clinical News ASH Self-Assessment Program Hematology , ASH Education Program About Awards Membership ASH Foundation ...

  2. Re-establishing dignity

    DEFF Research Database (Denmark)

    Høy, Bente; Hall, E.O.C

    2012-01-01

    In western countries, the older population is increasing and with age follows a risk of un-health. Every fifth hospital patient is above 65 years of age. As a consequence, nursing care to older patients is a significant but tacit nursing issue. The aim of this study was to explore Danish clinical...... nurses’ experiences of caring for older hospital patients. The study was based on Benner and Wrubel’s phenomenological notion that caring as a special kind of involvement, a grasp of a situation in terms of its meaning, is primary in nursing. A qualitative secondary analysis of data from an interview...... study with 29 nurses and nurse assistants was performed following Van Manen’s hermeneutic phenomenology. Findings show that caring mainly concerns ‘re-establishing dignity’ especially through ‘seeing the patient as a unique person’, ‘assisting in getting rid of the bed’ and ‘supporting patient...

  3. Establishing effective working relationships.

    Science.gov (United States)

    Houghton, Trish

    2016-02-24

    This article, the second in a series of 11, provides support and offers advice to new and existing mentors and practice teachers to enable them to progress in their role and develop a portfolio of evidence. In particular, the article discusses how to establish effective working relationships and emphasises the importance of the student-mentor or student-practice teacher relationship. It examines the essential qualities, attributes and characteristics of an effective mentor or practice teacher. The article provides learning activities and suggests ways in which mentors and practice teachers can undertake various self-assessments, enabling them to gather relevant evidence to demonstrate how they can meet and maintain the requirements for these roles as stipulated by the Nursing and Midwifery Council.

  4. My revision notes Edexcel GCSE computer science

    CERN Document Server

    Cushing, Steve

    2015-01-01

    Unlock your full potential with this revision guide which focuses on the key content and skills you need to know. With My Revision Notes for AQA GCSE Computer Science, which perfectly matches the latest examined elements of the course, you can: - Take control of your revision: plan and focus on the areas you need to revise, with advice, summaries and notes from author Steve Cushing - Show you fully understand key topics by using specific strategies and theories to add depth to your knowledge of programming and computing issues and processes - Apply programming and com

  5. My revision notes AQA GCSE English Language

    CERN Document Server

    Brindle, Keith

    2015-01-01

    Unlock your full potential with this revision guide for the new AQA GCSE English Language which focuses on the key content and skills you need to know. -Take control of your revision: plan and focus on the areas you need to revise. -Improve your exam skills with self-testing and exam-style questions. -Keep focused on what you need to know with Key Terms based around the exam questions. -Unpick each exam question with guidance on how to approach them and specific Revision Tasks

  6. Blood pressure measurement

    Science.gov (United States)

    Diastolic blood pressure; Systolic blood pressure; Blood pressure reading; Measuring blood pressure ... or your health care provider will wrap the blood pressure cuff snugly around your upper arm. The lower ...

  7. Blood Count Tests

    Science.gov (United States)

    Your blood contains red blood cells (RBC), white blood cells (WBC), and platelets. Blood count tests measure the number and types of cells in your blood. This helps doctors check on your overall health. ...

  8. Investigation on artificial blood or substitute blood replace the natural blood.

    Science.gov (United States)

    Keyhanian, Sh; Ebrahimifard, M; Zandi, M

    2014-01-01

    Blood is a liquid tissue in which dissolved with abundant chemical factors and millions of different cells The reduction of unwanted side effects, especially diseases that emerge through blood such as HIV and hepatitis, has a significant role for modern medicine of transfusion and transplantation. The issues and costs of human blood collection and storage, direct this procedure towards the use of alternatives blood. Two important research fields of this area were oxygen carriers based on hemoglobin and perfluoro chemicals. While they do not have the same quality as the blood cell products, the oxygen carrier solutions have potential clinical and non-clinical applications. The result showed that these products can reach to the body tissues easier than normal red blood cells, and can control the oxygen directly. The final aim of transfusion is to establish a transfusion system with no side effects, and the fact that oxygen carrier artificial blood has this property. The article attempts to step towards solving some problems of blood transfusion through describing the properties of artificial blood alternatives.

  9. Establishing lunar resource viability

    Science.gov (United States)

    Carpenter, J.; Fisackerly, R.; Houdou, B.

    2016-11-01

    Recent research has highlighted the potential of lunar resources as an important element of space exploration but their viability has not been demonstrated. Establishing whether or not they can be considered in future plans is a multidisciplinary effort, requiring scientific expertise and delivering scientific results. To this end various space agencies and private entities are looking to lunar resources, extracted and processed in situ, as a potentially game changing element in future space architectures, with the potential to increase scale and reduce cost. However, before any decisions can be made on the inclusion of resources in exploration roadmaps or future scenarios some big questions need to be answered about the viability of different resource deposits and the processes for extraction and utilisation. The missions and measurements that will be required to answer these questions, and which are being prepared by agencies and others, can only be performed through the engagement and support of the science community. In answering questions about resources, data and knowledge will be generated that is of fundamental scientific importance. In supporting resource prospecting missions the science community will de facto generate new scientific knowledge. Science enables exploration and exploration enables science.

  10. Revised

    DEFF Research Database (Denmark)

    Johannsen, Vivian Kvist; Nord-Larsen, Thomas; Riis-Nielsen, Torben

    and Energy and the Ministry of Environment. The report is based on the data from the Danish National Forest Inventory (NFI), performed for the Ministry of Environment and the SINKS project in relation to Article 3.4 of the Kyoto protocol for the Ministry of Climate and Energy. Forest & Landscape, Copenhagen...

  11. Revised seismic and geologic siting regulations for nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, A.J.; Chokshi, N.C. [Office of Nuclear Regulatory Research, Washington, DC (United States)

    1997-02-01

    The primary regulatory basis governing the seismic design of nuclear power plants is contained in Appendix A to Part 50, General Design Criteria for Nuclear Power Plants, of Title 10 of the Code of Federal Regulations (CFR). General Design Criteria (GDC) 2 defines requirements for design bases for protection against natural phenomena. GDC 2 states the performance criterion that {open_quotes}Structures, systems, and components important to safety shall be designed to withstand the effects of natural phenomena such as earthquakes, . . . without loss of capability to perform their safety functions. . .{close_quotes}. Appendix A to Part 100, Seismic and Geologic Siting Criteria for Nuclear Power Plants, has been the principal document which provided detailed criteria to evaluate the suitability of proposed sites and suitability of the plant design basis established in consideration of the seismic and geologic characteristics of the proposed sites. Appendix A defines required seismological and geological investigations and requirements for other design conditions such as soil stability, slope stability, and seismically induced floods and water waves, and requirements for seismic instrumentation. The NRC staff is in the process of revising Appendix A. The NRC has recently revised seismic siting and design regulations for future applications. These revisions are discussed in detail in this paper.

  12. Managing Software Requirements Changes Based on Negotiation-Style Revision

    Institute of Scientific and Technical Information of China (English)

    Ke-Dian Mu; Weiru Liu; Zhi Jin; Jun Hong; David Bell

    2011-01-01

    For any proposed software project,when the software requirements specification has been established,requirements changes may result in not only a modification of the requirements specification but also a series of modifications of all existing artifacts during the development.Then it is necessary to provide effective and flexible requirements changes management.In this paper,we present an approach to managing requirements changes based on Booth's negotiation-style framework for belief revision.Informally,we consider the current requirements specification as a belief set about the systemto-be.The request of requirements change is viewed as new information about the same system-to-be.Then the process of executing the requirements change is a process of revising beliefs about the system-to-be.We design a family of belief negotiation models appropriate for different processes of requirements revision,including the setting of the request of requirements change being fully accepted,the setting of the current requirements specification being fully preserved,and that of the current specification and the request of requirements change reaching a compromise.In particular,the prioritization of requirements plays an important role in reaching an agreement in each belief negotiation model designed in this paper.

  13. Steady Particle States of Revised Electromagnetics

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2006-07-01

    Full Text Available A revised Lorentz invariant electromagnetic theory leading beyond Maxwell’s equations, and to a form of extended quantum electrodynamics, has been elaborated on the basis of a nonzero electric charge density and a nonzero electric field divergence in the vacuum state. Among the applications of this theory, there are steady electromagnetic states having no counterpart in conventional theory and resulting in models of electrically charged and neutral leptons, such as the electron and the neutrino. The analysis of the electron model debouches into a point-charge-like geometry with a very small characteristic radius but having finite self-energy. This provides an alternative to the conventional renormalization procedure. In contrast to conventional theory, an integrated radial force balance can further be established in which the electron is prevented from “exploding” under the action of its net self-charge. Through a combination of variational analysis and an investigation of the radial force balance, a value of the electronic charge has been deduced which deviates by only one percent from that obtained in experiments. This deviation requires further investigation. A model of the neutrino finally reproduces some of the basic features, such as a small but nonzero rest mass, an angular momentum but no magnetic moment, and long mean free paths in solid matter.

  14. Steady Particle States of Revised Electromagnetics

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2006-07-01

    Full Text Available A revised Lorentz invariant electromagnetic theory leading beyond Maxwell's equations, and to a form of extended quantum electrodynamics, has been elaborated on the basis of a nonzero electric charge density and a nonzero electric field divergence in the vacuum state. Among the applications of this theory, there are steady electromagnetic states having no counterpart in conventional theory and resulting in models of electrically charged and neutral leptons, such as the electron and the neutrino. The analysis of the electron model debouches into a point-charge-like geometry with a very small characteristic radius but having finite self-energy. This provides an alternative to the conventional renormalization procedure. In contrast to conventional theory, an integrated radial force balance can further be established in which the electron is prevented from "exploding" under the action of its net self-charge. Through a combination of variational analysis and an investigation of the radial force balance, a value of the electronic charge has been deduced which deviates by only one percent from that obtained in experiments. This deviation requires further investigation. A model of the neutrino finally reproduces some of the basic features, such as a small but nonzero rest mass, an angular momentum but no magnetic moment, and long mean free paths in solid matter.

  15. 76 FR 66006 - Revised Medical Criteria for Evaluating Congenital Disorders That Affect Multiple Body Systems

    Science.gov (United States)

    2011-10-25

    ... trisomy (Edwards' syndrome or trisomy E) are usually expected to result in early death. Others such as cri... methods for establishing the existence of non-mosaic Down syndrome and other congenital disorders that... (section 110.00); Revise adult listing 10.06 and childhood listing 110.06 for non-mosaic Down syndrome;...

  16. 9 CFR 108.6 - Revision of plot plans, blueprints, and legends.

    Science.gov (United States)

    2010-01-01

    ..., and legends. 108.6 Section 108.6 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... FACILITY REQUIREMENTS FOR LICENSED ESTABLISHMENTS § 108.6 Revision of plot plans, blueprints, and legends..., blueprints, or legends and submit to Animal and Plant Health Inspection Service for review and filing...

  17. 78 FR 57503 - Revision to the Washington State Implementation Plan; Approval of Motor Vehicle Emission Budgets...

    Science.gov (United States)

    2013-09-19

    ... AGENCY 40 CFR Part 52 Revision to the Washington State Implementation Plan; Approval of Motor Vehicle Emission Budgets and Determination of Attainment for the 2006 24-Hour Fine Particulate Standard; Tacoma... November 28, 2012, to establish motor vehicle emission budgets for the Tacoma-Pierce County...

  18. A revision of the genus Parastasia in the Indo-Australian region (Coleoptera: Scarabaeidae: Rutelinae)

    NARCIS (Netherlands)

    Kuijten, P.J.

    1992-01-01

    A revision is presented of the species in the genus Parastasia. All known species are described, 11 new species are established, the parameres of most species are figured, the taxonomic levels of several taxa are changed, and 21 new synonymies are proposed. For many taxa lectotypes are designated an

  19. 75 FR 29420 - Revision of LNG and LHG Waterfront Facility General Requirements

    Science.gov (United States)

    2010-05-26

    ... No. USCG-2007-27022] RIN 1625-AB13 Revision of LNG and LHG Waterfront Facility General Requirements... requirements for waterfront facilities handling liquefied natural gas (LNG) and liquefied hazardous gas (LHG... harmonize the Coast Guard's regulations for LNG with those established by the Federal Energy...

  20. Structural, Item, and Test Generalizability of the Psychopathy Checklist-Revised to Offenders with Intellectual Disabilities

    Science.gov (United States)

    Morrissey, Catrin; Cooke, David; Michie, Christine; Hollin, Clive; Hogue, Todd; Lindsay, William R.; Taylor, John L.

    2010-01-01

    The Psychopathy Checklist-Revised (PCL-R) is the most widely used measure of psychopathy in forensic clinical practice, but the generalizability of the measure to offenders with intellectual disabilities (ID) has not been clearly established. This study examined the structural equivalence and scalar equivalence of the PCL-R in a sample of 185 male…

  1. 76 FR 31930 - Notice of Request for a Revision of a Currently Approved Information Collection (Marking...

    Science.gov (United States)

    2011-06-02

    ... the regulatory requirements for marking, labeling, and packaging of meat, poultry, and egg products; and for establishments that produce mechanically separated poultry. FSIS has revised its total annual burden estimate in light of the latest available data. Also, FSIS is requesting permission to use a...

  2. Revised State Budget Sells Kids Short

    Science.gov (United States)

    Children Now, 2012

    2012-01-01

    The Administration's May Revision of the 2012-2013 state budget addresses a $15.7 billion shortfall through funding shifts, cuts, and new revenue sources that place children squarely in harms way. California's kids are already grossly underserved relative to the rest of the nation's children. If the May Revise budget is passed by the Legislature,…

  3. Femoral revision surgery with impaction bone grafting

    NARCIS (Netherlands)

    B.L.E.F. ten Have (Bas); R.W. Brouwer (Reinoud); F.C. van Biezen (Frans); J.A.N. Verhaar (Jan)

    2012-01-01

    textabstractThe purpose of this prospective study was to evaluate the long-term clinical and radiological outcomes of revision of the femoral component of a total hip replacement using impaction bone grafting. Femoral revision with an impacted allograft was performed on 29 patients (31 hips). In all

  4. Evaluating Writing: Effects of Feedback on Revision.

    Science.gov (United States)

    Chaudron, Craig

    The effect of evaluation method on English as second language (ESL) learners' revisions of their compositions was investigated. Teacher comments, peer evaluations, and English-speaking peer reformulations were compared. Judges rated the revised compositions of 9 advanced and 14 intermediate college ESL students using the ESL Composition Profile.…

  5. Revision of the genus Endospermum Bth. (Euphorbiaceae)

    NARCIS (Netherlands)

    Schaeffer, J.

    1971-01-01

    The revision was undertaken because the latest monograph by Pax & Hoffmann, dating from 1912, did not provide a satisfactory key, and because since that time a very large amount of new material has been collected and several new species were described. In the present revision 12 species have been re

  6. Postoperative pain treatment' practice guideline revised

    NARCIS (Netherlands)

    Houweling, P.L.; Molag, M.L.; Boekel, R.L.M. van; Verbrugge, S.J.; Haelst, I.M. van; Hollmann, M.W.

    2013-01-01

    - On the initiative of the Dutch Association of Anaesthesiologists, a multidisciplinary workgroup has revised the 2003 practice guideline on 'Postoperative pain treatment' for adults and children.- The main reason for revision was the availability of new drugs and new methods of administration. The

  7. [Effectiveness of intervention by the infection control team for cancer patients with a positive blood culture].

    Science.gov (United States)

    Yamada, Tomoyuki; Suzuki, Kaoru; Ohi, Yukimasa; Kawanishi, Fumiko; Shibata, Yuriko; Hosomi, Makoto; Goto, Emi; Nishihara, Masami; Katsumata, Takahiro; Ukimura, Akira

    2013-11-01

    Cancer patients at a high risk of acquiring infectious diseases should be maintained in a facility where good infection control practices are followed. At our hospital, the infection control team(ICT)provides expertise, education, and support to the staff, helping them maintain proper standards, thereby minimizing the risks of infection. The ICT(established in 2004)has implemented infection control programs by employing an appropriate number of staff members after the revision of medical treatment fees in 2011. Our intervention program includes 2 general policies, namely, ordering and collection of blood cultures and intervention for the medical care of patients with positive blood cultures. In this study, we evaluated the effectiveness of our intervention for cancer patients with a positive blood culture. During the surveillance period(April 2011 to July 2012), 42 positive cases were determined to be infectious. ICT intervention was required in 37 cases. Our suggestions were accepted in 92%(34/37)of the cases, and improved outcome was estimated in 65%(22/34)of the cases. The results of our study contribute to the scientific bases on which routine clinical practices could be promoted in the future.

  8. Blood Glucose Levels

    Directory of Open Access Journals (Sweden)

    Carlos Estela

    2011-01-01

    Full Text Available The purpose of this study was to establish a mathematical model which can be used to estimate glucose levels in the blood over time. The equations governing this process were manipulated with the use of techniques such as separation of variables and integration of first order differential equations, which resulted in a function that described the glucose concentration in terms of time. This function was then plotted, which allowed us to find when glucose concentration was at its highest. The model was then used to analyze two cases where the maximum glucose level could not exceed a certain level while the amount of carbohydrates and glycemic index were varied, independently.

  9. Establishment of licensing process for development reactors

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Jong Chull; Yune, Young Gill; Kim, Woong Sik (and others)

    2006-02-15

    A study on licensing processes for development reactors has been performed to prepare the licensing of development reactors developed in Korea. The contents and results of the study are summarized as follows. The licensing processes for nuclear reactors in Korea, U.S.A., Japan, France, U.K., Canada, and IAEA were surveyed and analyzed to obtain technical bases necessary for establishing licensing processes applicable to development reactors in Korea. Based on the technical bases obtained the above analysis, the purpose, power output, and design characteristics of development reactors were analyzed in detail. The analysis results suggested that development reactors should be classified as a new reactor category (called as 'development reactor') separated from the current reactor categories such as the research reactor and the power reactor. Therefore, it is proposed to establish a new reactor category classified as 'development reactor' for the development reactors. And licensing processes, including licensing technical requirements, licensing document requirements, and other regulatory requirements, were also proposed for the development reactors. In order to institutionalize the licensing processes developed in this study, it is necessary to revise the current laws. Therefore, draft provisions of Atomic Energy Act, Enforcement Decree of the Atomic Energy Act, and Enforcement Regulation of the Atomic Energy Act have been developed for the preparation of the future legalization of the licensing processes proposed for the development reactors. Conclusively, a proposal of licensing processes and draft provisions of laws have been developed for the development reactors. The results proposed in this study can be applied directly to the licensing of the future development reactors. Furthermore, they will also contribute to establishing successfully the licensing processes of the development reactors.

  10. Low Blood Glucose (Hypoglycemia)

    Science.gov (United States)

    ... Disease, & Other Dental Problems Diabetes & Sexual & Urologic Problems Low Blood Glucose (Hypoglycemia) What is hypoglycemia? Hypoglycemia, also called low blood glucose or low blood sugar, occurs when ...

  11. 建立我国HIV阳转血浆盘并评价HIV酶免血筛试剂窗口期%Evaluation of HIV diagnosis kits used for blood screening with NIFDC-established HIV-1 seroconver-sion panels

    Institute of Scientific and Technical Information of China (English)

    黄维金; 宋爱京; 许四宏; 王佑春

    2016-01-01

    目的:建立我国HIV系列阳转血清盘并用其评价HIV酶免血筛诊断试剂的窗口期。方法收集HIV感染者的系列血清,利用Western blot确认试剂、HIV抗原定量检测试剂、核酸定量检测试剂等检测系列样品,RT-PCR的方法扩增HIV env序列并测序和分型,以确认HIV感染。对国内外5种第四代和14种第三代酶免HIV血液筛查诊断试剂的检测窗口期进行评价。结果共收集确认8套HIV感染者的阳转系列血浆,AE亚型6套,B亚型1套,未分型1套,共含有36份样品。用HIV系列阳转血清盘评价发现四代抗原抗体联合检测试剂较三代抗体检测试剂具有更早的窗口期检测能力,前者评分9.4分,后者3.6分,差异具有统计学意义(t=8.547,P<0.01);部分国产四代试剂质量已经达到进口试剂的水平;核酸试剂的窗口期检测能力高于酶免试剂,在3套血清盘中至少提高2周以上;确认试剂的灵敏度低于血筛试剂的灵敏度;4/5四代试剂在检测感染早期样品时会出现检测信号值/界值( S/CO)下降的情况,存在第二窗口期漏检风险。结论本研究建立了8套我国的HIV系列阳转血清盘,评价发现我国HIV血液筛查酶免诊断试剂窗口期检测能力存在差异。%Objective To establish HIV-1 seroconversion panels with the samples collected by National Institutes for Food and Drug Control ( NIFDC) and to evaluate the window periods of HIV enzyme immunoassay ( EIA) diagnostic kits used for blood screening with them. Methods Serum specimens were collected from different plasma donation stations in China. All suspected HIV infection specimens were screened for HIV by using the nucleic acid amplification testing (NAT), Western blot confirmatory assay and P24 quantitative detection assay. The HIV env gene sequences were amplified by RT-PCR for further confirmation of HIV infection. The PCR products were sequenced and genotyped. The confirmed seroconver-sion panels were used to

  12. Establishment of an in vitro blood-brain barrier model by co-culturing rat brain microvascular endothelial cells,pericytes and astrocytes%大鼠脑微血管内皮细胞与周细胞、星形胶质细胞共培养建立体外血脑屏障模型

    Institute of Scientific and Technical Information of China (English)

    查雨锋; 傅晓钟; 张顺; 罗敏; 欧瑜; 董永喜; 王爱民; 王永林

    2015-01-01

    目的:应用原代培养的大鼠脑微血管内皮细胞(brain-microvessel endothelial cells,BMECs )与脑微血管周细胞(brain-microvessel pericytes,BMPC )、星形胶质细胞(astro-cytes,AS)共培养建立可模拟在体状态的体外血脑屏障(blood-brain barrier,BBB)模型。方法原代分离、纯化和培养大鼠BMECs、BMPC和AS,通过细胞形态学和免疫细胞化学染色方法鉴定原代培养的细胞,应用Millicell细胞培养插(孔径0.4μm)建立5种不同类型的体外BBB模型,经跨内皮电阻值(transendothelial electrical resistance,TEER)、荧光素钠通透性(sodium fluorescent,Na-FLU )、碱性磷酸酶(AKP)和γ-谷氨酰转肽酶(γ-GT1)的表达测定以及阳性药在体内和体外BBB通透量的相似性,比较评价其屏障功能。结果原代培养的BMECs呈典型的铺路卵石样结构,BMPC胞体较大且呈分枝状,AS 有细长突触,胞质较浅;免疫细胞化学染色证实原代细胞为目标细胞;BMECs与BMPC、AS共培养后TEER值可达(478±25)Ω·cm2,Na-FLU 的表观渗透系数为[(8.23±0.78)×10-6]cm·s-1,AKP和γ-GT1表达分别为(6.90±0.27)金氏单位· g-1 Pro,(4.39±0.32)μg·g-1 Pro;阳性药在体外BBB的表观渗透系数(apparent permeability coefficient,Papp )与在体数据具有较好的相关性(R2=0.92)。结论原代培养的大鼠BMECs与BMPC、AS共培养建立的体外BBB模型在形态、结构及屏障功能方面具备BBB的基本特征,为研究BBB的生理学、病理学以及筛选化合物提供了一种有用工具。%Aim To establish in vitro blood-brain barrier (BBB) model with characteristics of simulation of in vivo BBB by primi-tive co-culture of brain-microvessel endothelial cells (BMECs) with brain-microvessel pericytes (BMPC)and astrocytes (AS). Methods BMECs,BMPC and AS from SD rats were primitively isolated,purified and cultured,and then

  13. 自外周血记忆B细胞体外活化和分化抗原特异性浆细胞的方法研究%Establishment of activation and differentiation of memory B cells into antigen-specific secreting cells from peripheral blood mononuclear cells in vitro

    Institute of Scientific and Technical Information of China (English)

    毕冬梅; 韩晓建; 石佳宁; 刘晔; 金艾顺

    2015-01-01

    Objective To isolate antigen specific antibody-secreting cells (plasma cells) for development of antibody drug,we established efficient methods for the activation and differentiation of memory B cells into plasma cells in human peripheral blood lymphocytes (PBMCs) in vitro.Methods PBMCs were isolated from peripheral blood of two healthy donors received hepatitis B vaccine (named Z and L,vaccination time for 3 years and 25 years,respectively.).We actived and induced PBMCs by adding cytokines (IL-2 and IL-4) and TLR activators (CpG or R848) for 6 days.Secreted antibodies in the culture supernatans were measured by enzyme-linked immunosorbent assay (ELISA).Antibody secreting cells (ASCs) were detected by enzyme-linked immuno spot assay (ELISPOT).Results IgG concentrations in group C treated with CpG DNA 2006 combined with anti-CD40 antibody and IL-2 and in group R treated with R848 combined with IL-2 were 80.87 ng/mL and 85.97 ng/mL,respectively.These IgG levels were significantly higher copmpared with that in control group (t =23.318,t =60.639,both P < 0.05).The results showed that group C and R were efficiently actived,and the group R was significantly more than the group C.Both activation methods could induce B cell differentiation into plasma cells in vitro.Further,to analyze whether antigen specific plasma cells could be induced using the established motheds,we activated memory B cells in PBMCs vaccinated with hepatitis B vaccine.We detected HBsAg specific IgG secreting cells at different cell densities (104 to 105 cells/culture),the results showed that the group R was significantly more than the control group(t =5.031,t =11.561,both P < 0.05).Conclusion We established the optimal method for B cell activation in vitro.This method could efficiently induce activation and differentiation of memory B cells from PBMCs into antigen-specific plasma cells.%目的 建立自人外周血淋巴细胞(PBMCs)中的记忆B细胞活化和分化特异性抗体分泌细胞(

  14. Radiological control manual. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Kloepping, R.

    1996-05-01

    This Lawrence Berkeley National Laboratory Radiological Control Manual (LBNL RCM) has been prepared to provide guidance for site-specific additions, supplements and interpretation of the DOE Radiological Control Manual. The guidance provided in this manual is one methodology to implement the requirements given in Title 10 Code of Federal Regulations Part 835 (10 CFR 835) and the DOE Radiological Control Manual. Information given in this manual is also intended to provide demonstration of compliance to specific requirements in 10 CFR 835. The LBNL RCM (Publication 3113) and LBNL Health and Safety Manual Publication-3000 form the technical basis for the LBNL RPP and will be revised as necessary to ensure that current requirements from Rules and Orders are represented. The LBNL RCM will form the standard for excellence in the implementation of the LBNL RPP.

  15. Taxonomic revision of Pseudolachnea and Pseudolachnella and establishment of Neopseudolachnella and Pseudodinemasporium gen. nov.

    Science.gov (United States)

    Hashimoto, Akira; Sato, Genki; Matsuda, Takahiro; Matsumura, Misato; Hatakeyama, Satoshi; Harada, Yukio; Ikeda, Hiroshi; Tanaka, Kazuaki

    2015-01-01

    The taxonomy of Pseudolachnea and Pseudolachnella is controversial. Some authors have regarded them as congeneric, whereas others have considered them to be distinct genera differentiated merely on the number of conidial septa. A total of 26 isolates of Pseudolachnea-like fungi were subjected to morphological examination and phylogenetic analyses of nuc rDNA internal transcribed spacers 1 and 2 and partial 28S sequences and partial sequence of the translation elongation factor 1α gene. The results indicated that our materials should be classified in four genera: Pseudolachnea, Pseudolachnella, and two new genera, Neopseudolachnella and Pseudodinemasporium. Although the monophyly of both Pseudolachnea and Pseudolachnella was confirmed, it was concluded that differences observed in the conidiomatal structure, such as thickness of basal stroma and the excipulum, were more reliable for their circumscription, instead of conidial septation. Neopseudolachnella was similar to Pseudolachnea and Pseudolachnella in conidial morphology but was characterized by the conidiomata lacking an excipulum, unlike members of the latter two genera. Pseudodinemasporium bore conidia morphologically similar to those of Dinemasporium but was differentiated from the latter by the conidiomata, which was composed of a well developed peridial structure. A total of 12 new species, namely three in Neopseudolachnella (N. acutispora, N. magnispora, N. uniseptata), one in Pseudodinemasporium (P. fabiforme) and eight in Pseudolachnella (P. asymmetrica, P. botulispora, P. brevicoronata, P. campylospora, P. complanata, P. falcatispora, P. fusiformis and P. pachyderma) are described and illustrated.

  16. 76 FR 4801 - Establishment of New Agency; Revision of Delegations of Authority

    Science.gov (United States)

    2011-01-27

    ... Federal Regulations is sold by the Superintendent of Documents. #0;Prices of new books are listed in the... Economics (``REE'') to the Administrator of the Cooperative State Research, Education, and Extension Service... for Under Secretary for Research, Research, Education, and Education, and Extension. Economics...

  17. [Blood transfusion: the challenges for tomorrow?].

    Science.gov (United States)

    Folléa, Gilles; Garraud, Olivier; Tiberghien, Pierre

    2015-02-01

    As any therapeutic means, blood transfusion requires regular evaluation, particularly for its indications, effectiveness and risks. The availability of randomized clinical trials, the evolution of the quality of blood components, and the economic constraints shared by all countries, all lead to rethink both transfusion therapy as a whole and the organization of the transfusion chain from donor to recipient. The main tools available to improve transfusion and the transfusion chain management are the following: programs of patient blood management (PBM) to optimize the use of blood products with a patient centred approach, blood supply management tools to improve the effectiveness and efficiency of the transfusion chain, donor management tools to adapt donor collections to the patients' needs in compliance with safety requirements for patients and donors, and coordination of these activities. A better understanding of these tools and their implementation will certainly be major challenges for transfusion medicine in the near future. Integrating these evolutions in regulations through the revision of the European Directives on blood and blood components (the review process is expected to be launched in 2015) should enroll them in the long term, for the benefit of patients, donors and all other stakeholders involved in the transfusion chain.

  18. Blood, Soy Milk, and Vitality: The Wartime Origins of Blood Banking in China, 1943-45.

    Science.gov (United States)

    Soon, Wayne

    2016-01-01

    This article examines the multiple meanings of blood transfusion and banking in modern China through the history of the first Chinese blood bank, established by the Overseas Chinese in 1943 to solicit blood for the war effort. Through investigating the attitudes of Chinese soldiers and civilians toward the blood bank, this article argues for the multiplicity of motivations underpinning society's attitudes toward blood banking and donation. Cultural notions of blood were an important but not the sole factor in their consideration. Ideas of nationalism and altruism played a role too. What eventually turned out to be most effective for most donors was the promise of eggs and soy milk for blood. Its economic value in the context of wartime scarcity was enough for many to abandon opposition to blood banking. By drawing attention to socioeconomic concerns in biomedical practices, this article provides an alternative examination of blood banking in modern societies.

  19. Blood safety in the world updated

    Institute of Scientific and Technical Information of China (English)

    Silvano Wandel

    2010-01-01

    @@ Blood safety is of paramount importance in any medical context, given that it represents one of the most impor-tant supportive procedures in medicine. Nearly all medical fields that lead with very critical patients will depend on blood products as part of supporting medical strategies (both clinical and surgical). Thus, it is im-portant that every country in the world relies on a well established national blood program.

  20. Drug Establishments Current Registration Site

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Drug Establishments Current Registration Site (DECRS) is a database of current information submitted by drug firms to register establishments (facilities) which...

  1. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... Initiative Research Programs and Awards View all Blood Current Issue First Edition Abstracts Blood Advances A peer- ... Get email updates View all meetings Publications Blood Current Issue First Edition Abstracts Blood Advances A peer- ...

  2. Hypertension (High Blood Pressure)

    Science.gov (United States)

    ... Surgery? A Week of Healthy Breakfasts Shyness Hypertension (High Blood Pressure) KidsHealth > For Teens > Hypertension (High Blood Pressure) Print ... rest temperature diet emotions posture medicines Why Is High Blood Pressure Bad? High blood pressure means a person's heart ...

  3. White Blood Cell Count

    Science.gov (United States)

    ... limited. Home Visit Global Sites Search Help? White Blood Cell Count Share this page: Was this page helpful? ... Count; Leukocyte Count; White Count Formal name: White Blood Cell Count Related tests: Complete Blood Count , Blood Smear , ...

  4. Lead levels - blood

    Science.gov (United States)

    Blood lead levels ... A blood sample is needed. Most of the time blood is drawn from a vein located on the inside ... may be used to puncture the skin. The blood collects in a small glass tube called a ...

  5. Blood donation before surgery

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000367.htm Blood donation before surgery To use the sharing features on ... described here. Blood From the Public (Volunteer Blood Donation) The most common source of blood given during ...

  6. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... infection) back to top How are Blood Clots in Pregnant Women Treated? Typically, blood clots are treated ... history of blood clots or blood clotting disorders in your family. Remain active, with your doctor's approval. ...

  7. High Blood Cholesterol

    Science.gov (United States)

    ... version of this page please turn Javascript on. High Blood Cholesterol What is High Blood Cholesterol? What is Cholesterol? Cholesterol is a ... heart disease. If Your Blood Cholesterol Is Too High Too much cholesterol in your blood is called ...

  8. Low Blood Pressure

    Science.gov (United States)

    ... a problem. Sometimes blood pressure that is too low can also cause problems. Blood pressure is the ... reading is 90/60 or lower, you have low blood pressure. Some people have low blood pressure ...

  9. Blood Transfusion (For Parents)

    Science.gov (United States)

    ... Old Feeding Your 1- to 2-Year-Old Blood Transfusions KidsHealth > For Parents > Blood Transfusions A A ... and help put your child at ease. About Blood Transfusions Blood is like the body's transportation system. ...

  10. Establishment of the HACCP Plan in a Catering Plant

    Directory of Open Access Journals (Sweden)

    U.C. Erkan

    2008-09-01

    Full Text Available In this study, HACCP (Hazard Analysis Critical Control Point plan was set up in a catering plant which had a capacity of 2000 persons/day and 40 employees. Founded HACCP system consisted of the following seven principles: (1 Conducting a hazard analysis, (2 determining the Critical Control Points (CCPs, (3 establishing critical limit(s, (4 establishing a system to monitor control of the CCP, (5 establishing the corrective action to be taken when monitoring indicates that a particular CCP is not under control, (6 establishing the procedures for verification that the HACCP system is working effectively and (7 documentation of all procedures and records appropriate to these principles and their application.That action was carried out by following this diagram: (1 Assembling HACCP team, (2 describing terms and intention, (3 describe product, (4 identifying intended use and consumer category, (5 constructing the flow diagram, (6 on-site confirmation of flow diagram, (7 listing all potential hazards and considering control measures, (8 determining CCPs, (9 establishing a monitoring system and critical limits for each CCP, (10 establishing the corrective actions, (11 keeping record procedure, (12 establishing verification procedures and, (13 revision of HACCP implementation.

  11. Dislocation following revision total hip arthroplasty.

    Science.gov (United States)

    Gioe, Terence J

    2002-04-01

    Dislocation is a relatively common complication following revision total hip arthroplasty. Risk factors include surgical approach, gender, underlying diagnosis, comorbidities, surgical experience, and previous surgery; for later dislocations, risk factors include wear/deformation of polyethylene, trauma, and decreased muscle strength. Prevention and precaution are the watchwords for dislocations following revision total hip arthroplasty. For dislocations that do occur, treatment rests first on identifying the source of instability. Most dislocations can be managed by closed reduction. Constrained components may increase success rates, but only for appropriate indications. Prevention and treatment of dislocations following revision total hip arthroplasty are discussed in this article.

  12. Caspofungin Etest susceptibility testing of Candida species: risk of misclassification of susceptible isolates of C. glabrata and C. krusei when adopting the revised CLSI caspofungin breakpoints.

    Science.gov (United States)

    Arendrup, Maiken Cavling; Pfaller, Michael A

    2012-07-01

    The purpose of this study was to evaluate the performance of caspofungin Etest and the recently revised CLSI breakpoints. A total of 497 blood isolates, of which 496 were wild-type isolates, were included. A total of 65/496 susceptible isolates (13.1%) were misclassified as intermediate (I) or resistant (R). Such misclassifications were most commonly observed for Candida krusei (73.1%) and Candida glabrata (33.1%). The revised breakpoints cannot be safely adopted for these two species.

  13. Nevada Test Site Radiological Control Manual. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2010-02-09

    This document supersedes DOE/NV/25946--801, “Nevada Test Site Radiological Control Manual,” Revision 0 issued in October 2009. Brief Description of Revision: A minor revision to correct oversights made during revision to incorporate the 10 CFR 835 Update; and for use as a reference document for Tenant Organization Radiological Protection Programs.

  14. A Comparative Study of Three Revision Methods in EFL Writing

    Science.gov (United States)

    Srichanyachon, Napaporn

    2011-01-01

    In an attempt to explore effective instruction in the English as a Foreign Language (EFL) setting, this study investigated language errors identified by students and teachers in three different revision stages: self-revision, peer revision, and teacher revision. It gave the focus to the effects of the three different methods on learners' writing…

  15. PEER REVISION OF WRITING IN L2 CLASSROOM

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Peer revision,a supplementary strategy to teacher revisionof writing in L2 classroom,makes passive receivers of teacherrevision become active revisers,enabling students to involve inmore motivated language learning.Benefits of peer revision andits implications for teacher and student roles are discussed.Thisarticle also tentatively analyzes ways of preparing students foreffective peer revision.

  16. [Comparative analysis of semiotic shifts, established by LCS of blood plasma from random samples of studied subjects from the zone of the Chernobyl accident, "Ural Radiation Trace", and collaborators from St. Petersburg Institute of Nuclear Physics of the Russian Academy of Sciences].

    Science.gov (United States)

    Ternovoĭ, K S; Selezneva, T N; Akleev, A V; Pashkov, I A; Noskin, L A; Klopov, N V; Noskin, V A; Starodub, N F

    1998-01-01

    Using the developed "semiotic" classifier of laser correlation spectra of blood plasma the authors have carried out the verification of organism states of patients from the zone of Chernobyl accident, "Ural radiation trace" and collaborators from Sanct-Petersbourg Institute of Nuclear Physics. An analysis of results obtained using accidental selections which differed as to the character of radiation injury evidences for high informativeness of "semiotic" classifier of laser correlation spectra of blood plasma.

  17. Quantum Field Theory, Revised Edition

    Science.gov (United States)

    Mandl, F.; Shaw, G.

    1994-01-01

    Quantum Field Theory Revised Edition F. Mandl and G. Shaw, Department of Theoretical Physics, The Schuster Laboratory, The University, Manchester, UK When this book first appeared in 1984, only a handful of W± and Z° bosons had been observed and the experimental investigation of high energy electro-weak interactions was in its infancy. Nowadays, W± bosons and especially Z° bosons can be produced by the thousand and the study of their properties is a precise science. We have revised the text of the later chapters to incorporate these developments and discuss their implications. We have also taken this opportunity to update the references throughout and to make some improvements in the treatment of dimen-sional regularization. Finally, we have corrected some minor errors and are grateful to various people for pointing these out. This book is designed as a short and simple introduction to quantum field theory for students beginning research in theoretical and experimental physics. The three main objectives are to explain the basic physics and formalism of quantum field theory, to make the reader fully proficient in theory calculations using Feynman diagrams, and to introduce the reader to gauge theories, which play such a central role in elementary particle physics. The theory is applied to quantum electrodynamics (QED), where quantum field theory had its early triumphs, and to weak interactions where the standard electro-weak theory has had many impressive successes. The treatment is based on the canonical quantization method, because readers will be familiar with this, because it brings out lucidly the connection between invariance and conservation laws, and because it leads directly to the Feynman diagram techniques which are so important in many branches of physics. In order to help inexperienced research students grasp the meaning of the theory and learn to handle it confidently, the mathematical formalism is developed from first principles, its physical

  18. Revision total knee arthroplasty using a custom tantalum implant in a patient following multiple failed revisions.

    Science.gov (United States)

    McNamara, Colin A; Gösthe, Raúl G; Patel, Preetesh D; Sanders, Kristopher C; Huaman, Gustavo; Suarez, Juan C

    2017-03-01

    The number of revision total knee arthroplasty procedures performed annually is increasing and, subsequently, so is the number of patients presenting following a failed revision. Rerevising a total knee arthroplasty after one or more failed revision procedures presents many challenges, including diminished bone stock for prosthetic fixation. "Off the shelf" implants may not offer the best alternative for reconstruction. We present the case of a 55-year-old patient who required a rerevision total knee arthroplasty following multiple failed revisions with severe femoral and tibia bone loss. We describe a novel technique we employed to improve component fixation within the compromised bone stock.

  19. A framework for revising preservice curriculum for nonphysician clinicians: The mozambique experience.

    Science.gov (United States)

    Freistadt, Fernanda; Branigan, Erin; Pupp, Chris; Stefanutto, Marzio; Bambo, Carlos; Alexandre, Maria; Pinheiro, Sandro O; Ballweg, Ruth; Dgedge, Martinho; O'Malley, Gabrielle; de Oliveira, Justine Strand

    2014-01-01

    Mozambique, with approximately 0.4 physicians and 4.1 nurses per 10,000 people, has one of the lowest ratios of health care providers to population in the world. To rapidly scale up health care coverage, the Mozambique Ministry of Health has pushed for greater investment in training nonphysician clinicians, Tιcnicos de Medicina (TM). Based on identified gaps in TM clinical performance, the Ministry of Health requested technical assistance from the International Training and Education Center for Health (I-TECH) to revise the two-and-a-half-year preservice curriculum. A six-step process was used to revise the curriculum: (i) Conducting a task analysis, (ii) defining a new curriculum approach and selecting an integrated model of subject and competency-based education, (iii) revising and restructuring the 30-month course schedule to emphasize clinical skills, (iv) developing a detailed syllabus for each course, (v) developing content for each lesson, and (vi) evaluating implementation and integrating feedback for ongoing improvement. In May 2010, the Mozambique Minister of Health approved the revised curriculum, which is currently being implemented in 10 training institutions around the country. Key lessons learned: (i) Detailed assessment of training institutions' strengths and weaknesses should inform curriculum revision. (ii) Establishing a Technical Working Group with respected and motivated clinicians is key to promoting local buy-in and ownership. (iii) Providing ready-to-use didactic material helps to address some challenges commonly found in resource-limited settings. (iv) Comprehensive curriculum revision is an important first step toward improving the quality of training provided to health care providers in developing countries. Other aspects of implementation at training institutions and health care facilities must also be addressed to ensure that providers are adequately trained and equipped to provide quality health care services. This approach to

  20. Facial Scar Revision: Understanding Facial Scar Treatment

    Science.gov (United States)

    ... a facial plastic surgeon Facial Scar Revision Understanding Facial Scar Treatment When the skin is injured from a cut or tear the body heals by forming scar tissue. The appearance of the scar can range from ...

  1. The revision of classical stock model

    Institute of Scientific and Technical Information of China (English)

    YE Bai-qing; WANG Hong-li

    2001-01-01

    On the basis of the analysis of classical stock model, according to th e limitation of the model, the article puts forward the revision of classical mo del and enforces the applicability of the stock model.

  2. 2013 FEMA Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  3. Parker River NWR : Revised Hunting Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document contains revisions to the 1978 Parker River National Wildlife Refuge Hunt Management Plan. Refuge hunters must obtain a permit to use the hunting...

  4. Suggested revision for west mexican archeological sequences.

    Science.gov (United States)

    Long, S V; Taylor, R E

    1966-12-16

    A review of the radiocarbon dates and published and unpublished archeological data from the West Mexican states of Sinaloa, Nayarit, Jalisco, and Colima has resulted in a revised tentative chronology for West Mexico.

  5. Strategies for Revision Total Ankle Replacement

    Directory of Open Access Journals (Sweden)

    Thomas S. Roukis, DPM, PhD, FACFAS

    2014-12-01

    Full Text Available As the frequency of primary total ankle replacement (TAR continues to build, revision will become more commonplace. At present there are no “standard principles” associated with revision TAR. What is clear is that the current approaches are technically complex, fraught with complications and no one approach represents the only answer. Exchange of TAR metallic components to the same system standard or dedicated revision components are viable options with limited occurrence of complications. Explantation and conversion to custom-design long stemmed components has limited availability. Explantation and conversion to another TAR system is high-risk and has strong potential for complications. The use of metal reinforced polymethylmethacrylate cement augmentation of failed TAR systems and tibio-talo-calcaneal arthrodesis should be reserved for very select situations where other options are not possible. There is a real need for long-term survivorship following revision TAR and future efforts ought to be directed in this area.

  6. The revision of classical stock model

    Institute of Scientific and Technical Information of China (English)

    叶柏青; 王洪利

    2001-01-01

    On the basis of the analysis of classical stock model, according to the limitation of the model, the article puts forward the revision of classical model and enforces the applicability of the stock model.

  7. Revised data taking schedule with ion beams

    CERN Document Server

    Gazdzicki, Marek; Aduszkiewicz, A; Andrieu, B; Anticic, T; Antoniou, N; Argyriades, J; Asryan, A G; Baatar, B; Blondel, A; Blumer, J; Boldizsar, L; Bravar, A; Brzychczyk, J; Bubak, A; Bunyatov, S A; Choi, K U; Christakoglou, P; Chung, P; Cleymans, J; Derkach, D A; Diakonos, F; Dominik, W; Dumarchez, J; Engel, R; Ereditato, A; Feofilov, G A; Fodor, Z; Ferrero, A; Gazdzicki, M; Golubeva, M; Grebieszkow, K; Grzeszczuk, A; Guber, F; Hasegawa, T; Haungs, A; Igolkin, S; Ivanov, A S; Ivashkin, A; Kadija, K; Katrynska, N; Kielczewska, D; Kikola, D; Kisiel, J; Kobayashi, T; Kolesnikov, V I; Kolev, D; Kolevatov, R S; Kondratiev, V P; Kowalski, S; Kurepin, A; Lacey, R; Laszlo, A; Lyubushkin, V V; Majka, Z; I Malakhov, A; Marchionni, A; Marcinek, A; Maris, I; Matveev, V; Melkumov, G L; Meregaglia, A; Messina, M; Mijakowski, P; Mitrovski, M; Montaruli, T; Mrówczynski, St; Murphy, S; Nakadaira, T; Naumenko, P A; Nikolic, V; Nishikawa, K; Palczewski, T; Pálla, G; Panagiotou, A D; Peryt, W; Planeta, R; Pluta, J; Popov, B A; Posiadala, M; Przewlocki, P; Rauch, W; Ravonel, M; Renfordt, R; Röhrich, D; Rondio, E; Rossi, B; Roth, M; Rubbia, A; Rybczynski, M; Sadovskii, A; Sakashita, K; Schuster, T; Sekiguchi, T; Seyboth, P; Shibata, M; Sissakian, A N; Skrzypczak, E; Slodkowski, M; Sorin, A S; Staszel, P; Stefanek, G; Stepaniak, J; Strabel, C; Ströbele, H; Susa, T; Szentpétery, I; Szuba, M; Tada, M; Taranenko, A; Tsenov, R; Ulrich, R; Unger, M; Vassiliou, M; Vechernin, V V; Vesztergombi, G; Wlodarczyk, Z; Wojtaszek, A; Zipper, W; CERN. Geneva. SPS and PS Experiments Committee; SPSC

    2009-01-01

    This document presents the revised data taking schedule of NA61 with ion beams. The revision takes into account limitations due to the new LHC schedule as well as final results concerning the physics performance with secondary ion beams. It is proposed to take data with primary Ar and Xe beams in 2012 and 2014, respectively, and to test and use for physics a secondary B beam from primary Pb beam fragmentation in 2010, 2011 and 2013.

  8. Revision of Khoikhoiinae (Hymenoptera, Braconidae

    Directory of Open Access Journals (Sweden)

    Michael Sharkey

    2009-09-01

    Full Text Available The species of the two genera of Khoikhoiinae (Hymenoptera, Braconidae are revised. Thirteen species are recognized, of which five are new and eight were previously described: Khoikhoia anthelion Sharkey, sp. n., K. lission Mason, 1984, K. oligospilos Sharkey, sp. n., K. semiadusta Mason, 1983, K. solata Mason, 1983, K. townesi Mason, 1983, K. turneri Mason, 1984, Sania browni Sharkey, sp. n., S. capensis Mason, 1983, S. henryi Mason, 1983, S. marjoriae Mason, 1983, S. masneri Sharkey, sp. n., and S. masoni Sharkey, sp. n.. All are from the Cape Region of South Africa, and all but one species are confined to the western Cape. A dichotomous key to species is presented; links to electronic interactive keys and to distribution maps are also included. Based on phylogenetic position and morphological characters, speculations on life history are made, and it is suggested that some species may be parasitoids of wood- or stem-boring Lepidoptera. The DELTA data matrix and images for the key are available at 10.3897/zookeys.20.108.app.1.ik; Intkey files are available at 10.3897/zookeys.20.108.app.2.ik; Lucid files in LIF and SDD format are available at doi:10.3897/zookeys.20.108.app.3.ik and doi:10.3897/zookeys.20.108.app.4.ik. Publishing of DELTA raw data will facilitate future workers to edit keys and to add newly discovered taxa.

  9. Photon Physics of Revised Electromagnetics

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2006-04-01

    Full Text Available Conventional theory, as based on Maxwell’s equations and associated quantum electrodynamical concepts in the vacuum, includes the condition of zero electric field divergence. In applications to models of the individual photon and to dense light beams such a theory exhibits several discrepancies from experimental evidence. These include the absence of angular momentum (spin, and the lack of spatially limited geometry in the directions transverse to that of the propagation. The present revised theory includes on the other hand a nonzero electric field divergence, and this changes the field equations substantially. It results in an extended quantum electrodynamical approach, leading to nonzero spin and spatially limited geometry for photon models and light beams. The photon models thereby behave as an entirety, having both particle and wave properties and possessing wave-packet solutions which are reconcilable with the photoelectric effect, and with the dot-shaped marks and interference patterns on a screen by individual photons in a two-slit experiment.

  10. HLW system plan - revision 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-14

    The projected ability of the Tank Farm to support DWPF startup and continued operation has diminished somewhat since revision 1 of this Plan. The 13 month delay in DWPF startup, which actually helps the Tank Farm condition in the near term, was more than offset by the 9 month delay in ITP startup, the delay in the Evaporator startups and the reduction to Waste Removal funding. This Plan does, however, describe a viable operating strategy for the success of the HLW System and Mission, albeit with less contingency and operating flexibility than in the past. HLWM has focused resources from within the division on five near term programs: The three evaporator restarts, DWPF melter heatup and completion of the ITP outage. The 1H Evaporator was restarted 12/28/93 after a 9 month shutdown for an extensive Conduct of Operations upgrade. The 2F and 2H Evaporators are scheduled to restart 3/94 and 4/94, respectively. The RHLWE startup remains 11/17/97.

  11. Revision of the DELFIC Particle Activity Module

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, David A [ORNL; Jodoin, Vincent J [ORNL

    2010-09-01

    The Defense Land Fallout Interpretive Code (DELFIC) was originally released in 1968 as a tool for modeling fallout patterns and for predicting exposure rates. Despite the continual advancement of knowledge of fission yields, decay behavior of fission products, and biological dosimetry, the decay data and logic of DELFIC have remained mostly unchanged since inception. Additionally, previous code revisions caused a loss of conservation of radioactive nuclides. In this report, a new revision of the decay database and the Particle Activity Module is introduced and explained. The database upgrades discussed are replacement of the fission yields with ENDF/B-VII data as formatted in the Oak Ridge Isotope Generation (ORIGEN) code, revised decay constants, revised exposure rate multipliers, revised decay modes and branching ratios, and revised boiling point data. Included decay logic upgrades represent a correction of a flaw in the treatment of the fission yields, extension of the logic to include more complex decay modes, conservation of nuclides (including stable nuclides) at all times, and conversion of key variables to double precision for nuclide conservation. Finally, recommended future work is discussed with an emphasis on completion of the overall radiation physics upgrade, particularly for dosimetry, induced activity, decay of the actinides, and fractionation.

  12. Minimally invasive transforaminal lumbar interbody fusion with unilateral pedicle screw fixation: comparison between primary and revision surgery.

    Science.gov (United States)

    Kang, Moo Sung; Park, Jeong Yoon; Kim, Kyung Hyun; Kuh, Sung Uk; Chin, Dong Kyu; Kim, Keun Su; Cho, Yong Eun

    2014-01-01

    Minimally invasive surgery with a transforaminal lumbar interbody fusion (MIS TLIF) is an important minimally invasive fusion technique for the lumbar spine. Lumbar spine reoperation is challenging and is thought to have greater complication risks. The purpose of this study was to compare MIS TLIF with unilateral screw fixation perioperative results between primary and revision surgeries. This was a prospective study that included 46 patients who underwent MIS TLIF with unilateral pedicle screw. The patients were divided into two groups, primary and revision MIS TLIF, to compare perioperative results and complications. The two groups were similar in age, sex, and level of operation, and were not significantly different in the length of follow-up or clinical results. Although dural tears were more common with the revision group (primary 1; revision 4), operation time, blood loss, total perioperative complication, and fusion rates were not significantly different between the two groups. Both groups showed substantial improvements in VAS and ODI scores one year after surgical treatment. Revision MIS TLIF performed by an experienced surgeon does not necessarily increase the risk of perioperative complication compared with primary surgery. MIS TLIF with unilateral pedicle screw fixation is a valuable option for revision lumbar surgery.

  13. Minimally Invasive Transforaminal Lumbar Interbody Fusion with Unilateral Pedicle Screw Fixation: Comparison between Primary and Revision Surgery

    Directory of Open Access Journals (Sweden)

    Moo Sung Kang

    2014-01-01

    Full Text Available Minimally invasive surgery with a transforaminal lumbar interbody fusion (MIS TLIF is an important minimally invasive fusion technique for the lumbar spine. Lumbar spine reoperation is challenging and is thought to have greater complication risks. The purpose of this study was to compare MIS TLIF with unilateral screw fixation perioperative results between primary and revision surgeries. This was a prospective study that included 46 patients who underwent MIS TLIF with unilateral pedicle screw. The patients were divided into two groups, primary and revision MIS TLIF, to compare perioperative results and complications. The two groups were similar in age, sex, and level of operation, and were not significantly different in the length of follow-up or clinical results. Although dural tears were more common with the revision group (primary 1; revision 4, operation time, blood loss, total perioperative complication, and fusion rates were not significantly different between the two groups. Both groups showed substantial improvements in VAS and ODI scores one year after surgical treatment. Revision MIS TLIF performed by an experienced surgeon does not necessarily increase the risk of perioperative complication compared with primary surgery. MIS TLIF with unilateral pedicle screw fixation is a valuable option for revision lumbar surgery.

  14. Requirements for Notification, Evaluation and Reduction of Lead-Based Paint Hazards in Federally Owned Residential Property and Housing Receiving Federal Assistance; Response to Elevated Blood Lead Levels. Final rule.

    Science.gov (United States)

    2017-01-13

    This final rule amends HUD's lead-based paint regulations to reduce blood lead levels in children under age six (6) who reside in federally-owned or -assisted pre-1978 housing, formally adopting a revised definition of "elevated blood lead level" (EBLL) in children under the age of six (6), in accordance with Centers for Disease Control and Prevention (CDC) guidance. It also establishes more comprehensive testing and evaluation procedures for the housing where such children reside. This final rule also addresses certain additional elements of the CDC guidance pertaining to assisted housing and makes technical corrections and clarifications. This final rule, which follows HUD's September 1, 2016, proposed rule, takes into consideration public comments submitted in response to the proposed rule.

  15. [Blood transfusion and supply chain management safety].

    Science.gov (United States)

    Quaranta, Jean-François; Caldani, Cyril; Cabaud, Jean-Jacques; Chavarin, Patricia; Rochette-Eribon, Sandrine

    2015-02-01

    The level of safety attained in blood transfusion now makes this a discipline better managed care activities. This was achieved both by scientific advances and policy decisions regulating and supervising the activity, as well as by the quality system, which we recall that affects the entire organizational structure, responsibilities, procedures, processes and resources in place to achieve quality management. So, an effective quality system provides a framework within which activities are established, performed in a quality-focused way and continuously monitored to improve outcomes. This system quality has to irrigate all the actors of the transfusion, just as much the establishments of blood transfusion than the health establishments.

  16. Chinese Women Lawyers Society Established

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    ON November 12, 1993, the Chinese Women Lawyers Society was established in Beijing. The more than 10,000 women lawyers in the country were excited to have their own organization. Xu Weihua, secretary-general of the society and a lawyer working in the All-China Women’s Federation, said: "The society’s establishment will promote the participation of

  17. 76 FR 33879 - Endangered and Threatened Wildlife and Plants; Revised Endangered Status, Revised Critical...

    Science.gov (United States)

    2011-06-09

    ... and Threatened Wildlife and Plants; Revised Endangered Status, Revised Critical Habitat Designation... and Wildlife Service 50 CFR Part 17 RIN 1018-AX18 Endangered and Threatened Wildlife and Plants... the currently endangered plant taxon, Monardella linoides ssp. viminea, in which the subspecies...

  18. Asynchronicity of facial blood perfusion in migraine.

    Directory of Open Access Journals (Sweden)

    Nina Zaproudina

    Full Text Available Asymmetrical changes in blood perfusion and asynchronous blood supply to head tissues likely contribute to migraine pathophysiology. Imaging was widely used in order to understand hemodynamic variations in migraine. However, mapping of blood pulsations in the face of migraineurs has not been performed so far. We used the Blood Pulsation Imaging (BPI technique, which was recently developed in our group, to establish whether 2D-imaging of blood pulsations parameters can reveal new biomarkers of migraine. BPI characteristics were measured in migraineurs during the attack-free interval and compared to healthy subjects with and without a family history of migraine. We found a novel phenomenon of transverse waves of facial blood perfusion in migraineurs in contrast to healthy subjects who showed synchronous blood delivery to both sides of the face. Moreover, the amplitude of blood pulsations was symmetrically distributed over the face of healthy subjects, but asymmetrically in migraineurs and subjects with a family history of migraine. In the migraine patients we found a remarkable correlation between the side of unilateral headache and the direction of the blood perfusion wave. Our data suggest that migraine is associated with lateralization of blood perfusion and asynchronous blood pulsations in the facial area, which could be due to essential dysfunction of the autonomic vascular control in the face. These findings may further enhance our understanding of migraine pathophysiology and suggest new easily available biomarkers of this pathology.

  19. Asynchronicity of facial blood perfusion in migraine.

    Science.gov (United States)

    Zaproudina, Nina; Teplov, Victor; Nippolainen, Ervin; Lipponen, Jukka A; Kamshilin, Alexei A; Närhi, Matti; Karjalainen, Pasi A; Giniatullin, Rashid

    2013-01-01

    Asymmetrical changes in blood perfusion and asynchronous blood supply to head tissues likely contribute to migraine pathophysiology. Imaging was widely used in order to understand hemodynamic variations in migraine. However, mapping of blood pulsations in the face of migraineurs has not been performed so far. We used the Blood Pulsation Imaging (BPI) technique, which was recently developed in our group, to establish whether 2D-imaging of blood pulsations parameters can reveal new biomarkers of migraine. BPI characteristics were measured in migraineurs during the attack-free interval and compared to healthy subjects with and without a family history of migraine. We found a novel phenomenon of transverse waves of facial blood perfusion in migraineurs in contrast to healthy subjects who showed synchronous blood delivery to both sides of the face. Moreover, the amplitude of blood pulsations was symmetrically distributed over the face of healthy subjects, but asymmetrically in migraineurs and subjects with a family history of migraine. In the migraine patients we found a remarkable correlation between the side of unilateral headache and the direction of the blood perfusion wave. Our data suggest that migraine is associated with lateralization of blood perfusion and asynchronous blood pulsations in the facial area, which could be due to essential dysfunction of the autonomic vascular control in the face. These findings may further enhance our understanding of migraine pathophysiology and suggest new easily available biomarkers of this pathology.

  20. New concepts in revision total knee arthroplasty.

    Science.gov (United States)

    Vince, Kelly G; Droll, Kurt; Chivas, Dan

    2008-01-01

    Revision knee arthroplasty should be regarded as a discipline separate from primary surgery. A disciplined approach to diagnosis is mandatory in which the following categories for failure are useful: (a) sepsis, (b) extensor mechanism rupture, (c) stiffness, (d) instability, (e) periprosthetic fracture, (f) aseptic loosening and osteolysis, (g) patellar complications and malrotation, (h) component breakage, and (i) no diagnosis. In the event of no coherent explanation for pain and disability, the possibilities of chronic regional pain syndrome, hip or spine pathology, and inability of current technology to meet patient expectations should be considered and revision surgery should be avoided. Revision arthroplasty cannot be performed as if it were a primary procedure and indeed will be eight (or more) different surgeries depending on the cause of failure. Though perhaps counterintuitive, there is a logical rationale and empirical evidence to support complete revision in virtually every case. In general, revision implant systems are required. The early dependence on the "joint line" is inadequate, failing as it does to recognize that the level of the articulation is a three-dimensional concept and not simply a "line." The key to revision surgery technique is that the flexion gap is determined by femoral component size and the extension gap by proximal distal component position. Accordingly, a general technical pathway of three steps can be recommended: 1) tibial platform; 2) stabilization of the knee in flexion with (a) femoral component rotation and (b) size selected with evaluation of (c) patellar height as an indication of "joint line" in flexion only; and 3) stabilization of the knee in extension, an automatic step. Stem extensions improve fixation and, if they engage the diaphysis, may be used as a guide for positioning. Porous metals designed as augments for bone defects may prove more important as "modular fixation interfaces." It is postulated that with the

  1. [Analysis and comparison of theories of circulation of blood and qi in both eastern and western ancient medicines].

    Science.gov (United States)

    Wang, Tai

    2014-09-01

    In ancient Egypt, the theory of circulation of blood and qi was preliminarily established on the basis of cadaver dissection, gradually revised and improved following the progress of anatomy and physiology. However, the "Meridian Theory" of circulation of blood and qi in Chinese medicine had never been established on the basis of anatomical and physiological studies. Thus a suspicion was aroused, "whether the meridians really exist, or artificially assumed by imagination"? Therefore, in recent one half of a century, numerous scholars at home and abroad spent countless financial capacities and human power to study the essence of Meridians in order to find their material or substantial evidence, but with no breakthrough obtained. Nevertheless, in the 70th of the last century, studies on mechanisms of acupuncture analgesia and acupuncture anesthesia won an undoubtedly good result. Hence, the therapeutic effect of acupuncture on pain control was admitted by the "Consensus Statement on Acupuncture" at an international meeting held by NIH in Dec. 1997. Then the old Chinese acupuncture won an international acceptance and application. Therefore, the investigation of mechanism of acupuncture analgesia set up a positive model for future scientific researches on acupuncture mechanisms and essence of Meridians, as well as on other Chinese medical theories.

  2. Unforced Revision in Processing Relative Clause Association Ambiguity in Japanese: Evidence Against Revision as Last Resort.

    Science.gov (United States)

    Yamada, Toshiyuki; Arai, Manabu; Hirose, Yuki

    2016-11-19

    The current study tackles a long standing question of whether comprehenders perform structural revision when it is not forced by grammar or not. Using an eye-tracking reading paradigm, we addressed this issue by making use of global structural ambiguity in Japanese. Our results show that comprehenders initially associate a relative clause with the first potential head noun and that they revise this analysis when the second noun is lexico-semantically possible as the relative clause head, but do not when it is impossible. The results are incompatible with the Revision as Last Resort hypothesis. Instead, they support the parsing with unforced revision that is immediately sensitive to lexical properties. We argue that our results cannot be accounted for by serial modular processing models but that they can be explained by ranked-parallel interactive processing models. Furthermore, we propose that head-finality is a key factor involved in the availability of unforced revision.

  3. Blood vessels, circulation and blood pressure.

    Science.gov (United States)

    Hendry, Charles; Farley, Alistair; McLafferty, Ella

    This article, which forms part of the life sciences series, describes the vessels of the body's blood and lymphatic circulatory systems. Blood pressure and its regulatory systems are examined. The causes and management of hypertension are also explored. It is important that nurses and other healthcare professionals understand the various mechanisms involved in the regulation of blood pressure to prevent high blood pressure or ameliorate its damaging consequences.

  4. Blood donor: nursing care plan

    Directory of Open Access Journals (Sweden)

    Marco Antonio Zapata Sampedro

    2008-11-01

    Full Text Available The standardized nursing care plan can be used as a means through which the nurse will assess and identify the particular needs of the blood donor.To draw up the care plan, we have conducted the evaluation on the basis of the Marjory Gordon’s functional health patterns.The more prevailing diagnosis according to the NANDA taxonomy have been identified, results have been established according to the NOC (Nursing Outcomes Classification taxonomy, and nursing interventions have been suggested according to the NIC (Nursing Interventions Classification taxonomy. Also, certain potential complications, which are infrequent, must be observed and controlled in the blood donation process. Our main aim with this article has been to offer to professionals resources that grant to the caring activity scientific rigor, professional recognition and an unique and valid tool to evaluate the assistance with the best levels of quality for the blood donor.

  5. Blood stain pattern analysis.

    Science.gov (United States)

    Peschel, O; Kunz, S N; Rothschild, M A; Mützel, E

    2011-09-01

    Bloodstain pattern analysis (BPA) refers to the collection, categorization and interpretation of the shape and distribution of bloodstains connected with a crime. These kinds of stains occur in a considerable proportion of homicide cases. They offer extensive information and are an important part of a functional, medically and scientifically based reconstruction of a crime. The following groups of patterns can essentially be distinguished: dripped and splashed blood, projected blood, impact patterns, cast-off stains, expirated and transferred bloodstains. A highly qualified analysis can help to estimate facts concerning the location, quality and intensity of an external force. A sequence of events may be recognized, and detailed questions connected with the reconstruction of the crime might be answered. In some cases, BPA helps to distinguish between accident, homicide and suicide or to identify bloodstains originating from a perpetrator. BPA is based on systematic training, a visit to the crime scene or alternatively good photographic documentation, and an understanding and knowledge of autopsy findings or statements made by the perpetrator and/or victim. A BPA working group has been established within the German Society of Legal Medicine aiming to put the knowledge and practical applications of this subdiscipline of forensic science on a wider basis.

  6. Transuranic waste baseline inventory report. Revision No. 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    The Transuranic Waste Baseline Inventory Report (TWBIR) establishes a methodology for grouping wastes of similar physical and chemical properties from across the U.S. Department of Energy (DOE) transuranic (TRU) waste system into a series of {open_quotes}waste profiles{close_quotes} that can be used as the basis for waste form discussions with regulatory agencies. The purpose of Revisions 0 and 1 of this report was to provide data to be included in the Sandia National Laboratories/New Mexico (SNL/NM) performance assessment (PA) processes for the Waste Isolation Pilot Plant (WIPP). Revision 2 of the document expanded the original purpose and was also intended to support the WIPP Land Withdrawal Act (LWA) requirement for providing the total DOE TRU waste inventory. The document included a chapter and an appendix that discussed the total DOE TRU waste inventory, including nondefense, commercial, polychlorinated biphenyls (PCB)-contaminated, and buried (predominately pre-1970) TRU wastes that are not planned to be disposed of at WIPP.

  7. Blood Culture (For Parents)

    Science.gov (United States)

    ... Feeding Your 1- to 2-Year-Old Blood Culture KidsHealth > For Parents > Blood Culture Print A A ... adjust the treatment choice. Why Do a Blood Culture? During some illnesses, certain infection-causing bacteria and ...

  8. Coughing up blood

    Science.gov (United States)

    ... gastrointestinal tract. Blood that comes up with a cough often looks bubbly because it is mixed with ... conditions, diseases, and medical tests may make you cough up blood. These include: Blood clot in the ...

  9. High Blood Pressure

    Science.gov (United States)

    ... normal blood pressure 140/90 or higher is high blood pressure Between 120 and 139 for the top number, ... prehypertension. Prehypertension means you may end up with high blood pressure, unless you take steps to prevent it. High ...

  10. High Blood Pressure (Hypertension)

    Science.gov (United States)

    ... Print Page Text Size: A A A Listen High Blood Pressure (Hypertension) Nearly 1 in 3 American adults has ... weight. How Will I Know if I Have High Blood Pressure? High blood pressure is a silent problem — you ...

  11. What Is Blood?

    Science.gov (United States)

    ... Foundation for America's Blood Centers ADRP What is blood? PUBLICATIONS EDUCATION PRESS ROOM BLOG CAREERS CONTACT ABC ... for patients who need it. One unit of blood can be separated into the following components: Nearly ...

  12. Ketones blood test

    Science.gov (United States)

    ... Ketones - serum; Nitroprusside test; Ketone bodies - serum; Ketones - blood ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel slight ... there may be some throbbing or a slight bruise. This soon ...

  13. Magnesium blood test

    Science.gov (United States)

    Magnesium - blood ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel slight pain. Others feel a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon ...

  14. CEA blood test

    Science.gov (United States)

    Carcinoembryonic antigen blood test ... A blood sample is needed . ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

  15. Glucagon blood test

    Science.gov (United States)

    ... type I - glucagon test; Hypoglycemia - glucagon test; Low blood sugar - glucagon test ... A blood sample is needed . ... When the needle is inserted to draw blood, some people feel ... Afterward, there may be some throbbing or a slight bruise. This ...

  16. Special Blood Donation Procedures

    Science.gov (United States)

    ... takes about 10 minutes. Double red blood cell donation In the so-called double red blood cell ... can be cured with apheresis. Directed or designated donation Family members or friends can donate blood specifically ...

  17. Home blood sugar testing

    Science.gov (United States)

    Diabetes - home glucose testing; Diabetes - home blood sugar testing ... Usual times to test your blood sugar are before meals and at bedtime. Your provider may ask you to check your blood sugar 2 hours after a meal. Ask ...

  18. High blood sugar

    Science.gov (United States)

    ... High blood glucose - self-care; Diabetes - high blood sugar ... Symptoms of high blood sugar can include: Being very thirsty or having a dry mouth Having blurry vision Having dry skin Feeling weak or tired ...

  19. Hyperglycemia (High Blood Glucose)

    Medline Plus

    Full Text Available ... Blood Pressure Physical Activity High Blood Glucose My Health Advisor Tools To Know Your Risk Alert Day ... DKA (Ketoacidosis) & Ketones Kidney Disease (Nephropathy) Gastroparesis Mental Health Step On Up Treatment & Care Blood Glucose Testing ...

  20. Blood and Diversity

    Science.gov (United States)

    ... patient diversity. For example, U-negative and Duffy-negative blood types are unique to the African-American community. ... most common blood type and because type O negative blood, in particular, is the universal type needed for ...

  1. Blood Pressure Test

    Science.gov (United States)

    ... an online personal health record or blood pressure tracker, for example. This gives you the option of ... lower your blood pressure. Exercise regularly. Regular physical activity can help lower your blood pressure and keep ...

  2. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... First Edition Abstracts Blood Advances A peer-reviewed, online only, open access journal with a unique focus ... help: Results of Clinical Studies Published in Blood Search Blood , the official journal of ASH, for the ...

  3. Symptoms of Blood Disorders

    Science.gov (United States)

    ... leg (causing most often swelling, redness, and/or warmth of the leg or shortness of breath) Petechiae ( ... Disorders Symptoms of Blood Disorders Medical History and Physical Examination for Blood Disorders Laboratory Tests for Blood ...

  4. Low Blood Pressure (Hypotension)

    Science.gov (United States)

    ... and rises sharply on waking. Blood pressure: How low can you go? What's considered low blood pressure ... even life-threatening disorders. Conditions that can cause low blood pressure Some medical conditions can cause low ...

  5. Red blood cell production

    Science.gov (United States)

    ... to one part of the body or another. Red blood cells are an important element of blood. Their job ... is carried to and eliminated by the lungs. Red blood cells are formed in the red bone marrow of ...

  6. Qualitative analysis fingertip patterns in ABO blood group

    Directory of Open Access Journals (Sweden)

    S. V. KShirsagar

    2013-05-01

    Full Text Available The inheritance of the dermatoglyphic patterns is polygenic. The genetic basis of the blood group is well established. The correlation between the dermatoglyphic patterns and the ABO blood group is studied by some workers in different populations. In the present study, the correlation between dermatoglyphics and ABO blood group is studied in the Marathwada Region of Maharashtra. The qualitative data included fingertip patterns and three indices. It was observed that, the Arch pattern is more common in blood group O both in male and female. Ulnar loop is most common in the blood group AB. Simple whorl and double loop whorl patterns are less frequent in blood group AB. Accidentals were not recorded in blood group A while blood group O show highest percentage of accidentals. Dankmeijer’s index was highest in blood group AB and lowest in blood group B.

  7. Recently revised diagnostic reference levels in nuclear medicine in Bulgaria and in Finland.

    Science.gov (United States)

    Korpela, H; Bly, R; Vassileva, J; Ingilizova, K; Stoyanova, T; Kostadinova, I; Slavchev, A

    2010-01-01

    An EU twinning project entitled 'Strengthening of administrative structures for radiation protection and safe use of ionising radiation in diagnostics and therapy' was established between Bulgaria and Finland, lasting from June 2008 to May 2009. One component of the project was to improve the optimisation of patient protection in nuclear medicine (NM) through revising diagnostic reference levels (DRLs). The revised DRLs are based on national surveys on the numbers of NM procedures and activities given to the patients in different procedures. The survey in Bulgaria was carried out in 2008 and that in Finland in 2007. National DRLs were established for the most frequent and dose-relevant examinations. The proposed DRLs in both countries are in good agreement with other national recommendations in Europe.

  8. 慢性心力衰竭心气虚兼血瘀水肿证大鼠模型的建立与整合判定%Establishment of Chronic Heart Failure Rat Model of Xin-qi Deficiency Complicated Blood Stasis and Edema Syndrome and Judgment of Diagnosis Information Integration

    Institute of Scientific and Technical Information of China (English)

    林家茂; 郭伟星; 王营; 刘颖; 李亚茹; 李珩; 周杰

    2014-01-01

    血瘀水肿证的SD大鼠模型.%Objective To establish and evaluate chronic heart failure (CHF) rat model of Xin-qi deficiency complicated blood stasis and edema syndrome (XQD-BSES).Methods Totally 40 SD rats were randomly divided into the normal control group (Control),the propylthiouracil (PTU) group,the adriamycin (ADR),and the ADR + PTU group.Normal saline was used as equivalent solvent of each group.Rats in the Control group were intragastrically and intraperitoneally injected with normal saline.Rats in the PTU group were intragastrically injected with PTU suspension and intraperitoneally injected with normal saline.Rats in the ADR group were intragastrically injected with ADR solution and intraperitoneally injected with normal saline.And rats in the ADR + PTU group were intragastrically injected with PTU suspension and intraperitoneally injected with ADR solution.The dose of PTU was 0.2% of daily forage weight,once daily.The dose of ADR was 3.5 mg/kg,once per week.The modeling lasted for 6 weeks.Left ventricular ejection fraction (LVEF),left ventricular fraction shortening (LVFS),brain natriuretic peptide (BNP),heart rate (HR),respiratory rate (RR),urine output,ear temperature,exhaustive swimming test (EST),Tri-iodothyronine (T3),tetra-iodothyronine (T4),thyroid stimulating hormone (TSH) as well as heart,lung,liver weight indices and their pathological sections were integrated and compared.Results Compared with the Control group,LVEF,LVFS,BNP,HR,RR,heart,lung,liver weight indices,urine output,ear temperature,EST,and T3,T4,and TSH changed significantly in the ADR group,the PTU group,and the ADR + PTU group with statistical significance (P <0.05),and pathological changes of heart failure occurred in pathological sections of heart,lung,and liver.Compared with the ADR group,LVEF,LVFS,BNP,and lung,liver weight indices,urine output,ear temperature,T3,T4,and TSH changed significantly in the ADR + PTU group with statistical significance (P < 0.05),and

  9. How to establish a company

    OpenAIRE

    Konečný, Viktor

    2008-01-01

    This diploma thesis is focused on a franchising business establishment, particularly on the business establishment of a fictive coffe house which could become a well known franchising concept on the Czech market. Primary advantage of franchise compared to the other types of business cooperation is mainly risk reduction for the investor (franchisee) who obtains proven model of the business. For the franchisor the franchise means an easier way how to widen his business without taking higher lab...

  10. Incidence of Complications During Initial Experience with Revision of the Agility and Agility LP Total Ankle Replacement Systems: A Single Surgeon's Learning Curve Experience.

    Science.gov (United States)

    Roukis, Thomas S; Simonson, Devin C

    2015-10-01

    As the frequency in which foot and ankle surgeons are performing primary total ankle replacement (TAR) continues to build, revision TAR will likely become more commonplace, creating a need for an established benchmark by which to evaluate the safety of revision TAR as determined by the incidence of complications. Currently, no published data exist on the incidence of intraoperative and early postoperative complications during revision of the Agility or Agility LP Total Ankle Replacement Systems during the surgeon learning curve period; therefore, the authors sought to determine this incidence during the senior author's learning curve period.

  11. At-risk children's use of reflection and revision in hands-on experimental activities

    Science.gov (United States)

    Petrosino, Anthony J., Jr.

    The goal of this study was to investigate the effects of incorporating opportunities for reflection and revision in hands-on science instruction which emphasized experimentation using model rockets. The participants were low achieving sixth grade summer school students (n = 23) designated as at-risk for school failure by their district. The group was asked a series of interview questions based on work by Schauble et al. (1995) relating to experimentation. The interviews took place over three distinct time points corresponding to a "hands-on only" condition, a "hands-on with reflection and revision" condition and a "hands-on with repeated reflection and revision" condition. A Friedman's Two-Way Analysis of Variance by Ranks indicate students score low at first with traditional hands-on instruction but improve significantly with opportunities to reflect and revise their experiments. In addition, a sociocultural analysis was conducted during the summer school session to assess the model rocket activity as an apprenticeship, as guided participation and as participatory appropriation using a framework established by Rogoff (1994). Finally, a survey (the Classroom Environment Survey) was administered to the students measuring five constructs consistent with a constructivist classroom: participation, autonomy, relevance, commitment to learning and disruptions to learning. Analysis indicate students in the summer school model rocket intervention experienced a greater sense of constructivist principles during the activity than a similar comparison group utilizing reform minded instruction but not including opportunities for reflection and revision cycles. This research provides important evidence that, like scientists, students in school can learn effectively from extended practice in a varied context. Importantly, the data indicate that hands-on instruction is best utilized when opportunities for reflection and revision are made explicit. Implications are discussed related

  12. 75 FR 36060 - Notice of Request for Extension of Approval of an Information Collection; Blood and Tissue...

    Science.gov (United States)

    2010-06-24

    ... Collection; Blood and Tissue Collection at Slaughtering and Rendering Establishments AGENCY: Animal and Plant... collection associated with regulations for blood and tissue collection at slaughtering and rendering... FURTHER INFORMATION CONTACT: For information on regulations for blood and tissue collection...

  13. Revised planetary protection policy for solar system exploration.

    Science.gov (United States)

    DeVincenzi, D L; Stabekis, P D

    1984-01-01

    In order to control contamination of planets by terrestrial microorganisms and organic constituents, U.S. planetary missions have been governed by a planetary protection (or planetary quarantine) policy which has changed little since 1972. This policy has recently been reviewed in light of new information obtained from planetary exploration during the past decade and because of changes to, or uncertainties in, some parameters used in the existing quantitative approach. On the basis of this analysis, a revised planetary protection policy with the following key features is proposed: deemphasizing the use of mathematical models and quantitative analyses; establishing requirements for target planet/mission type (i.e., orbiter, lander, etc.) combinations; considering sample return missions a separate category; simplifying documentation; and imposing implementing procedures (i.e., trajectory biasing, cleanroom assembly, spacecraft sterilization, etc.) by exception, i.e., only if the planet/mission combination warrants such controls.

  14. US Department of Energy radiological control manual. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-01

    This manual establishes practices for the conduct of Department of Energy radiological control activities. The Manual states DOE`s positions and views on the best courses of action currently available in the area of radiological controls. Accordingly, the provisions in the Manual should be viewed by contractors as an acceptable technique, method or solution for fulfilling their duties and responsibilities. This Manual shall be used by DOE in evaluating the performance of its contractors. This Manual is not a substitute for Regulations; it is intended to be consistent with all relevant statutory and regulatory requirements and shall be revised whenever necessary to ensure such consistency. Some of the Manual provisions, however, challenge the user to go well beyond minimum requirements. Following the course of action delineated in the Manual will result in achieving and surpassing related statutory or regulatory requirements.

  15. NRC drug-free workplace plan. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    On September 15, 1986, President Reagan signed Executive Order 12564, establishing the goal of a Drug-Free Federal Workplace. The Order made it a condition of employment that all Federal employees refrain from using illegal drugs on or off duty. On July 11, 1987, Congress passed legislation affecting implementation of the Executive Order under Section 503 of the Supplemental Appropriations Act of 1987, Public Law 100-71 (the Act). The Nuclear Regulatory Commission first issued the NRC Drug Testing Plan to set forth objectives, policies, procedures, and implementation guidelines to achieve a drug-free Federal workplace, consistent with the Executive Order and Section 503 of the Act. Revision 1, titled, ``NRC Drug-Free Workplace Plan,`` supersedes the previous version and its supplements and incorporates changes to reflect current guidance from the Department of Justice, the Department of Health and Human Services, as well as other guidance.

  16. A revision of the genus Parastasia in the Indo-Australian region (Coleoptera: Scarabaeidae: Rutelinae)

    OpenAIRE

    Kuijten, P.J.

    1992-01-01

    A revision is presented of the species in the genus Parastasia. All known species are described, 11 new species are established, the parameres of most species are figured, the taxonomic levels of several taxa are changed, and 21 new synonymies are proposed. For many taxa lectotypes are designated and many specimens bearing incorrect or dubious type labels are degraded to their true status. Some aspects of distribution and dispersal are shortly discussed. A tentative key and a check list are a...

  17. Systematic revision of the family Pleioplanidae Faubel, 1983 (Polycladida, Acotylea: new genus and combinations

    Directory of Open Access Journals (Sweden)

    Jorge Rodríguez

    2017-01-01

    Full Text Available New morphological information, reconsiderations and the first combination of a generic name based on a previously established species are presented in the current revision of the family Pleioplanidae (Polycladida, Acotylea. Species belonging to this family are briefly presented and Laqueusplana bocki gen. et sp. nov. is described. An identification key to all valid species of Pleioplanidae is provided. Furthermore, results from phylogenetic analyses of the species treated herein are discussed.

  18. Pediatric Audiology Report: Assessment and Revision of an Audiology Report Written to Parents of Children with Hearing Impairment

    Science.gov (United States)

    Donald, Ashleigh J.; Kelly-Campbell, Rebecca J.

    2016-01-01

    Objective: The purpose of this study was twofold: first, to evaluate a typical pediatric diagnostic audiology report to establish its readability and comprehensibility for parents and, second, to revise the report to improve its readability, as well as the comprehension, sense of self-efficacy, and positive opinions of parent readers. Method: In…

  19. 77 FR 73674 - Ammonium Nitrate From Ukraine; Notice of Revised Schedule of the Five-year Review Concerning the...

    Science.gov (United States)

    2012-12-11

    ...)] Ammonium Nitrate From Ukraine; Notice of Revised Schedule of the Five-year Review Concerning the Antidumping Duty Order on Ammonium Nitrate From Ukraine AGENCY: United States International Trade Commission... established a schedule for the conduct of the 5-year review of Ammonium Nitrate from Ukraine (77 FR...

  20. 75 FR 79412 - Final Revised Assessment of Annual Needs for the List I Chemicals Ephedrine, Pseudoephedrine, and...

    Science.gov (United States)

    2010-12-20

    ... Phenylpropanolamine for 2010'' was published in the Federal Register (75 FR 36684). This notice proposed the revised... established the 2010 assessment of annual needs for ephedrine (for sale) at 3,600 kg (74 FR 60298). As noted... phenylpropanolamine (for sale) at 6,400 kg (74 FR 60298). As noted above, DEA utilized the same general...

  1. Cord blood stem cell banking and transplantation.

    Science.gov (United States)

    Dhot, P S; Nair, V; Swarup, D; Sirohi, D; Ganguli, P

    2003-12-01

    Stem cells have the ability to divide for indefinite periods in culture and to give rise to specialized cells. Cord blood as a source of hematopoietic stem cells (HSC) has several advantages as it is easily available, involves non-invasive collection procedure and is better tolerated across the HLA barrier. Since the first cord blood transplant in 1988, over 2500 cord blood HSC transplants have been done world wide. Since then, the advantages of cord blood as a source of hematopietic stem cells for transplantation have become clear. Firstly, the proliferative capacity of HSC in cord blood is superior to that of cells in bone marrow or blood from adults. A 100 ml unit of cord blood contains 1/10th the number of nucleated cells and progenitor cells (CD34+ cells) present in 1000 ml of bone marrow, but because they proliferate rapidly, the stem cell in a single unit of cord blood can reconstitute the entire haematopoietic system. Secondly, the use of cord blood reduces the risk of graft vs host disease. Cord Blood Stem Cell banks have been established in Europe and United States to supply HSC for related and unrelated donors. Currently, more than 65,000 units are available and more than 2500 patients have received transplants of cord blood. Results in children have clearly shown that the number of nucleated cells in the infused cord blood influences the speed of recovery of neutrophils and platelets after myeloablative chemotherapy. The optimal dose is about 2 x 10(7) nucleated cells/kg of body weight. The present study was carried out for collection, separation, enumeration and cryopreservation of cord blood HSC and establishing a Cord Blood HSC Bank. 172 samples of cord blood HSC were collected after delivery of infant prior to expulsion of placenta. The average cord blood volume collected was 101.20 ml. Mononuclear cell count ranged from 7.36 to 25.6 x 10(7)/ml. Viability count of mononuclear cells was 98.1%. After 1 year of cryopreservation, the viability count on

  2. An Operational Approach to Belief Revision

    Institute of Scientific and Technical Information of China (English)

    张玉平; 李未

    1996-01-01

    A deduction system,called RE-proof system,is constructed for generating the revisions of first order belief sets.When a belief set is rejected by a given fact,all maximal subsets of the belief set consistent with the fact can be deduced from the proof system.The soundness and completeness of the RE-proof system are proved,which imply that there exists a resolution method to decide whether a revision retains a maximal subset of a belief set.

  3. Misassigned natural products and their revised structures.

    Science.gov (United States)

    Yoo, Hye-Dong; Nam, Sang-Jip; Chin, Young-Won; Kim, Min-Sun

    2016-02-01

    Natural products are a major pipeline for drug development and are responsible for more than 50 % of drugs on the market. NMR is a fundamental and powerful tool for the structure determination of natural products. It is essential to provide unambiguous chemical structure information on natural products in drug development research, including the structure-activity relationship, derivatization and pharmacokinetic/pharmacodynamic studies. Advancement of NMR instruments has made it possible to deal with nanomole-scale natural products for structure elucidation, but misinterpretation of NMR spectra still occurs. We review 21 natural products with revised chemical structures and the methods used for those revisions.

  4. Plan-Belief Revision in Jason

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Villadsen, Jørgen

    2015-01-01

    When information is shared between agents of unknown reliability, it is possible that their belief bases become inconsistent. In such cases, the belief base must be revised to restore consistency, so that the agent is able to reason. In some cases the inconsistent information may be due to use of...... of incorrect plans. We extend work by Alechina et al. to revise belief bases in which plans can be dynamically added and removed. We present an implementation of the algorithm in the AgentSpeak implementation Jason....

  5. AN OVERVIEW ON BLOOM'S REVISED TAKSONOMY

    OpenAIRE

    TUTKUN, Ömer Faruk

    2013-01-01

    In this study, the main purpose is to present the main frame of revised version in 2001 of Bloom's taxonomy that has been accepted extensively in our country since 1956 as well as around the world. In accordance with this purpose, in the study, answers have been searched to these questions: 1- The rise of the original Bloom's taxonomy and what are the key features of? 2- What are the reasons for renewal of original taxonomy? 3- What kind of arrangements has been made in revised taxonomy? 4- W...

  6. Resource description and access 2013 revision

    CERN Document Server

    2013-01-01

    This e-book contains the 2013 Revision of RDA: Resource Description and Access, and includes the July 2013 Update. This e-book offers links within the RDA text and the capability of running rudimentary searches of RDA, but please note that this e-book does not have the full range of content or functionality provided by the subscription product RDA Toolkit. Included: A full accumulation of RDA- the revision contains a full set of all current RDA instructions. It replaces the previous version of RDA Print as opposed to being an update packet to that version. RDA has gone through many changes sin

  7. A programmable approach to revising knowledge bases

    Institute of Scientific and Technical Information of China (English)

    LUAN Shangmin; DAI Guozhong; LI Wei

    2005-01-01

    This paper presents a programmable approach to revising knowledge bases consisting of clauses. Some theorems and lemmas are shown in order to give procedures for generating maximally consistent subsets. Then a complete procedure and an incomplete procedure for generating the maximal consistent subsets are presented, and the correctness of the procedures is also shown. Furthermore, a way to implement knowledge base revision is presented, and a prototype system is introduced. Compared with related works, the main characteristic of our approach is that the approach can be implemented by a computer program.

  8. Joint Line Reconstruction in Navigated Total Knee Arthroplasty Revision

    Science.gov (United States)

    2012-05-16

    Revision Total Knee Arthroplasty Because of; Loosening; Instability; Impingement; or Other Reasons Accepted as Indications for TKA Exchange.; The Focus is to Determine the Precision of Joint Line Restoration in Navigated vs. Conventional Revision Total Knee Arthroplasty

  9. 76 FR 75782 - Revising Standards Referenced in the Acetylene Standard

    Science.gov (United States)

    2011-12-05

    ... the Acetylene Standard AGENCY: Occupational Safety and Health Administration (OSHA), Department of... is revising its Acetylene Standard for general industry by updating a reference to a standard... and Explanation of Revisions to the Acetylene Standard IV. Procedural Determinations A....

  10. 地中海贫血患者来源外周血及脐带血细胞诱导式多能干细胞的建系和造血分化%Establishment of the thalassemia patient-specific induced pluripotent stem cells from peripheral and cord blood ;cells and its hematopoietic differentiation

    Institute of Scientific and Technical Information of China (English)

    曾敏慧; 蒋满波; 艳飞; 彭澄; 张滨; 蔡柳洪

    2015-01-01

    Objective To investigate the construction and hematopoietic differentiation of induced pluripotent stem cells ( iPSCs) from thalassemia patients .Methods Cord blood from artificial labored fetus with HbH disease (α-thalassemia) and peripheral blood from a case of heterozygote of β-thalassemia (genotype IVS-II-654/CD17) were obtained.The iPSCs were re-programed from mononuclear cells separated from obtained cord blood and peripheral blood . Hematopoietic stem cell differentiation was induced by OP 9 cell co-culture.The pluripotent markers of iPSCs were detec-ted by immunofluorescence and alkaline phosphatase staining , while embryoid bodies ( EBs) and teratoma forming experi-ments were used to detect the pluripotency .Results Pluripotent biomarkers , including Oct4, SSEA4, tra-1-60 and tra-1-81, and alkaline phosphatase , were positive on iPSCs.EBs were formed by suspended culture .Three germ layer cells were found in the teratoma test .The results of flow cytometry showed that CD 34+cells was 4.46%and 8.71%from cord blood and peripheral sources , respectively, after co-cultured with OP9 cells.Conclusion Cord blood and periph-eral blood MNCs of patients with αorβthalassemia, can be reprogrammed into iPSCs , and differentiated into hematopoi-etic stem cells.%目的:探讨地中海贫血(地贫)患者特异诱导式多能干细胞系( iPSCs)细胞模型的建立及造血分化能力。方法采集HbH病引产胎儿(α地贫)的脐带血、双重杂合子β地贫输血患者(基因型为IVS-Ⅱ-654/CD17)外周血各1例,分离单核细胞后进行短期培养,核转染再程序化为iPSCs,检测iPSCs未分化状态和多能性标志物。 iPSCs与OP9细胞共培养向造血干细胞诱导分化,进行吉姆萨染色检查和流式细胞术检测造血干细胞的分化结果。结果地贫患者iPSCs表达干细胞多能性标志物Oct4、SSEA4、Tra-1-60、Tra-1-81,碱式磷酸酶染色阳性,悬浮培养可以形成类

  11. 人外周血树突状细胞体外稳定培养方法的建立及与磁珠法的比较%Establishment of in vitro stable culture of human peripheral blood dendritic cells and its comparation with magnetic activated cell sorting

    Institute of Scientific and Technical Information of China (English)

    单骄宇; 刘弓伯; 吐尔洪江·吐尔逊; 张雪; 阿尔孜古丽·吐逊; 林仁勇; 温浩

    2010-01-01

    Objective To establish a economic and stable method to induce and culture dendritic cells (DCs) from peripheral blood of human being, and compare with the magnetic activated cell sorting. Methods Monocytes were isolated from health donors peripheral blood mononuclear cells(PBMC) by density gradient separation,cultured and compared with that of cells isolated by the magnetic activated cell sorting or adherent culture,respectively. PBMC were cultured with recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) and recombinant human interleukin-4(rhIL-4) for 6 days to induce the growth of DCs. Morphological changes was observed under inverted microscope. Meanwhile, cell viability was tested at the 3rd, 5th, 6th day,respectively. The phenotypes, like CD14, CDla, HLA-DR were analyzed with flow cytometry after PBMC were adherent cultured for 1, 2, 5 h. After adding human recombinant cytokines, the phenotypes of acquired cells surface markers, CD14, CD1a, CD86, CD83 and HLA-DR would be detected and compared with flow cytometry. T cells proliferating activity was determined by allogeneic mixed lymphocyte reaction in vitro. Results After adherent culture for 2 h, the acquired DCs showed typical morphology. Cell viability was decreased at days 5th, 6th[(53.333 ±5.774)%,(38.333 ± 7.638)%] than that at day of 3rd[(68.667 ± 3.215)%, all P < 0.05] with the magnetic activated cell sorting, but with adherent culture method, the difference was not statistically significant (F = 0.737,P> 0.05) at days of 3rd, 5th, 6th[(92.667 ± 3.055)%,(94.000 ± 1.000)%,(94.667 ± 1.528)%]. Moreover,compared with the magnetic activated cell sorting, there were differences in cell viability of adherent culture method at days of 3rd, 5th, 6th(t = 9.374, 12.021,12.527, all P < 0.05). Before and after using the magnetic activated cell sorting, the expression of CD14 were (32.457 ± 12.351) %, (41.914 ± 14.858)%, respectively. The difference was not statistically

  12. Treating High Blood Pressure

    Science.gov (United States)

    About High Blood Pressure Many people in the United States die from high blood pressure. This condition usually does not cause symptoms. Most ... until it is too late. A person has high blood pressure when the blood pushes against Visit your doctor ...

  13. Hypertension (High Blood Pressure)

    Science.gov (United States)

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Hypertension (High Blood Pressure) KidsHealth > For Teens > Hypertension (High Blood Pressure) A ... rest temperature diet emotions posture medicines Why Is High Blood Pressure Bad? High blood pressure means a person's heart ...

  14. BUN - blood test

    Science.gov (United States)

    Blood urea nitrogen ... A blood sample is needed. Most of the time blood is drawn from a vein located on the inside ... Many medicines can interfere with blood test results. Your health ... if you need to stop taking any medicines before you have this ...

  15. Introduction to Iranian Blood Transfusion Organization and Blood Safety in Iran

    Directory of Open Access Journals (Sweden)

    H Abolghasemi

    2009-03-01

    Full Text Available "nCurrently, in Iran blood transfusion is an integral part of the national health system and blood donation is voluntary and non­remu­nerated and blood and its components may not be a source of profit. In 1974 and following establishment of Iranian Blood Transfusion Organization (IBTO all blood transfusion activities from donor recruitment to production of blood com­po­nents and delivery of blood and blood products were centralized. The activities of IBTO are followed the laws and regu­la­tions of Ministry of Health and criteria of Iran National Regulatory Authority. In order to meet the country's demand in 2007 IBTO collected about 1.7 millions units of blood from the population of 70 millions. In 1979 coincided with the Is­lamic revolution the number of  blood units collected throughout the country were 124,000 units or 3.4 unit per 1000 popu­la­tion whereas after about 30 years this increased to about 25 unit per 1000 population. With improving the pool of vol­un­tary donors, IBTO has been successful in excluding "family replacement" donation since 2007 and reached to 100% volun­tary and nonremunerated blood donation. Currently more than 92% of blood donors in Iran are male and contribution of fe­male in blood donation is less than 8%. Although all donated blood in Iran screened for HBsAg since 1974, screening of blood units for HIV and HCV started since 1989 and 1996, respectively. The frequency of HBV infection in blood do­nors showed a significant decline from 1.79% in 1998 to 0.4% in 2007. The overall frequency of HCV and HIV infection are 0.13% and 0.004% respectively.

  16. Revised Law Provides Better Protection for Minor Citizens

    Institute of Scientific and Technical Information of China (English)

    JU QING

    2007-01-01

    @@ On December 29, 2006, the revised Law of the People's Republic of China on the Protection of Minors(hereinafter referred to as "the revised Law" for short) was approved at the 25th meeting of the Tenth National People's Congress (NPC), China's highest legislature. The revised Law is to become effective on June 1, 2007. Revision of the Law, which was adopted in 1991, took three years to complete, during which period a dozen drafts were produced.

  17. Establishing operations and the mand.

    Science.gov (United States)

    Michael, J

    1988-01-01

    In Verbal Behavior Skinner identifies a small number of elementary verbal relations, one of which is the mand. Because its introduction is at first in terms of unlearned motivative variables, and because the mand's relation to prior controlling events is quite complex, its general significance has probably been underestimated. An extensive treatment of establishing operations, including the warning and the blocked-response conditioned establishing operations is provided, followed by a description of the mand in terms of such operations. The importance of the mand for language training programs is suggested, as well as the reasons why it is typically neglected in such programs.

  18. Acoustic comfort in eating establishments

    DEFF Research Database (Denmark)

    Svensson, David; Jeong, Cheol-Ho; Brunskog, Jonas

    2014-01-01

    The subjective concept of acoustic comfort in eating establishments has been investigated in this study. The goal was to develop a predictive model for the acoustic comfort, by means of simple objective parameters, while also examining which other subjective acoustic parameters could help explain...... the feeling of acoustic comfort. Through several layers of anal ysis, acoustic comfort was found to be rather complex, and could not be explained entirely by common subjective parameters such as annoyance, intelligibility or privacy. A predictive model for the mean acoustic comfort for an eating establishment...

  19. 78 FR 44596 - Minor Boundary Revision at Yosemite National Park

    Science.gov (United States)

    2013-07-24

    ... National Park Service Minor Boundary Revision at Yosemite National Park AGENCY: National Park Service, Interior. ACTION: Notification of Boundary Revision. SUMMARY: The boundary of Yosemite National Park is... boundary of Yosemite National Park. DATES: The effective date of this boundary revision is July 24,...

  20. Uncovering Substance: Teaching Revision in High School Classrooms

    Science.gov (United States)

    Early, Jessica Singer; Saidy, Christina

    2014-01-01

    This article shares the process and outcomes from a three-day revision workshop designed and implemented in a diverse high school language arts classroom. The revision workshop included: direct instruction, self-reflection, and peer feedback to provide struggling writers with opportunities to take part in substantive revision. The authors examine…

  1. Integrating Relational Reasoning and Knowledge Revision during Reading

    Science.gov (United States)

    Kendeou, Panayiota; Butterfuss, Reese; Van Boekel, Martin; O'Brien, Edward J.

    2017-01-01

    Our goal in this theoretical contribution is to connect research on knowledge revision and relational reasoning. To achieve this goal, first, we review the "knowledge revision components framework" (KReC) that provides an account of knowledge revision processes, specifically as they unfold during reading of texts. Second, we review a…

  2. Assessing the Impact of Peer Revision on L2 Writing.

    Science.gov (United States)

    Villamil, Olga S.; de Guerrero, Maria C. M.

    1998-01-01

    A study investigated the impact of peer revision on writers' final drafts in two rhetorical modes, narration and persuasion, among 14 Spanish-speaking college students of English-as-a-Second-Language. Results revealed 74% of revisions made in peer sessions were incorporated into final drafts, and writers made many further self-revisions,…

  3. Rewriting: What Do Deaf Students Do When They Revise?

    Science.gov (United States)

    Gormley, Kathleen A.; Sarachan-Deily, Ann Beth

    The study investigated revision skills of 20 deaf secondary students (10 good writers and 10 poor writers). Students were asked to write and then revise their draft. Feature analytical rating was completed on each S's draft and revision, with scoring performed on content, linguistic considerations, and surface mechanics (spelling, punctuation,…

  4. Blood lead levels and chronic blood loss

    Energy Technology Data Exchange (ETDEWEB)

    Manci, E.A.; Cabaniss, M.L.; Boerth, R.C.; Blackburn, W.R.

    1986-03-01

    Over 90% of lead in blood is bound to the erythrocytes. This high affinity of lead for red cells may mean that chronic blood loss is a significant means for excretion of lead. This study sought correlations between blood lead levels and clinical conditions involving chronic blood loss. During May, June and July, 146 patients with normal hematocrits and red cell indices were identified from the hospital and clinic populations. For each patient, age, race, sex and medical history were noted, and a whole blood sample was analyzed by flameless atomic absorption spectrophotometry. Age-and race-matched pairs showed a significant correlation of chronic blood loss with lead levels. Patients with the longest history of blood loss (menstruating women) had the lowest level (mean 6.13 ..mu..g/dl, range 3.6-10.3 ..mu..g/dl). Post-menopausal women had levels (7.29 ..mu..g/dl, 1.2-14 ..mu..g/dl) comparable to men with peptic ulcer disease, or colon carcinoma (7.31 ..mu..g/dl, 5.3-8.6 ..mu..g/dl). The highest levels were among men who had no history of bleeding problems (12.39 ..mu..g/dl, 2.08-39.35 ..mu..g/dl). Chronic blood loss may be a major factor responsible for sexual differences in blood lead levels. Since tissue deposition of environmental pollutants is implicated in diseases, menstruation may represent a survival advantage for women.

  5. 77 FR 13393 - Endangered and Threatened Wildlife and Plants; Revised Endangered Status, Revised Critical...

    Science.gov (United States)

    2012-03-06

    ... morphological and ecological description and diminished range. We also present our revised designation of... reference Monardella viminea as M. linoides ssp. viminea, and may include statements or data referring...

  6. Outcome, revision rate and indication for revision following resurfacing hemiarthroplasty for osteoarthritis of the shoulder

    DEFF Research Database (Denmark)

    Rasmussen, J V; Polk, A; Sorensen, A K

    2014-01-01

    In this study, we evaluated patient-reported outcomes, the rate of revision and the indications for revision following resurfacing hemiarthroplasty of the shoulder in patients with osteoarthritis. All patients with osteoarthritis who underwent primary resurfacing hemiarthroplasty and reported...... to the Danish Shoulder Arthroplasty Registry (DSR), between January 2006 and December 2010 were included. There were 772 patients (837 arthroplasties) in the study. The Western Ontario Osteoarthritis of the Shoulder (WOOS) index was used to evaluate patient-reported outcome 12 months (10 to 14) post......-operatively. The rates of revision were calculated from the revisions reported to the DSR up to December 2011 and by checking deaths with the Danish National Register of Persons. A complete questionnaire was returned by 688 patients (82.2%). The mean WOOS was 67 (0 to 100). A total of 63 hemiarthroplasties (7...

  7. Dworkin's prudent insurance ideal: two revisions

    OpenAIRE

    Kurtulmuş, Ahmet Faik; Kurtulmus, Ahmet Faik

    2012-01-01

    This article offers two revisions to Dworkin’s ‘prudent insurance ideal’, which aims to account for justice in the distribution of healthcare so that (a) it can deal with market failures in healthcare and (b) when applied to unjust societies it addresses health problems caused by injustice in a fair manner.

  8. Notes on the revised standard edition.

    Science.gov (United States)

    Solms, Mark

    2013-02-01

    On the eve of the publication of the Revised Standard Edition of the Complete Psychological Works of Sigmund Freud (24 volumes) and The Complete Neuroscientific Works of Sigmund Freud (4 volumes), the editor of these works describes the policies he followed in succeeding James Strachey, and reflects on the experience of doing so.

  9. Revised Recommendation Concerning Technical and Vocational Education.

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    The UNESCO (United Nations Education, Scientific, and Cultural Organization) revised recommendation setting forth general principles, goals, and guidelines concerning technical and vocational education (adopted by the General Conference at its 18th session in Paris, 19 November 1974) is presented under the following headings: (1) Technical and…

  10. A revision of the genus Podococcus

    NARCIS (Netherlands)

    Valkenburg, van J.L.C.H.; Sunderland, T.

    2008-01-01

    A taxonomic revision of the palm genus Podococcus (Arecaceae) is presented. Two species are recognised: P. barteri, a species relatively widespread in a coastal band from Nigeria to the D. R. Congo and P. acaulis, a species previously considered conspecific to P. barteri, almost exclusively confined

  11. EMC (Electromagnetic Compatibility) Standards Handbook. Revision 4,

    Science.gov (United States)

    1982-11-01

    Regulations arc prepared EMC November 1982 3-2 STANDARDS HANDBOOK REVISION DATE SECTION-PAGE by VDE Standards Committees (VDE Normen Ausschuss). Individual...regulation has a well- % publicized review that is coordinated with the German Standards Institute (Deutches Institute fuer Normen , DIN) and the German

  12. Revision der Gattung Orophea Blume (Annonaceae)

    NARCIS (Netherlands)

    Keßler, P.J.A.

    1988-01-01

    The genus Orophea Blume (Annonaceae: Saccopetaleae) has been revised with the following main results: — The genus in the circumscription of most authors is not monophyletic, but biphyletic. The genus Mezzettiopsis Ridley has to be reinstated. — Pseuduvaria, Mitrephora, Petalolophus, Oreomitra, Schef

  13. Audience and Revision: Middle Schoolers "Slam" Poetry.

    Science.gov (United States)

    Jester, Judith

    1997-01-01

    Describes organizing a poetry "slam" (a contest in which people read their original poems and listeners cast votes for their favorites) involving 200 eighth graders from two different schools. Discusses how this experience made vivid for students the need to write for an audience and to revise. (SR)

  14. Revised definitions of women's sexual dysfunction

    NARCIS (Netherlands)

    Basson, Rosemary; Leiblum, Sandra; Brotto, Lori; Derogatis, Leonard; Fourcroy, Jean; Fugl-Meyer, Kerstin; Graziottin, Alessandra; Heiman, Julia R.; Laan, Ellen; Meston, Cindy; Schover, Leslie; van Lankveld, Jacques; Schultz, Willibrord Weijmar

    2004-01-01

    Introduction. Existing definitions of women's sexual disorders are based mainly on genitally focused events in a linear sequence model (desire, arousal and orgasm). Aim. To revise definitions based on an alternative model reflecting women's reasons/incentives for sexual activity beyond any initial a

  15. 7 CFR 3015.115 - Budget revisions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Budget revisions. 3015.115 Section 3015.115 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF THE CHIEF FINANCIAL OFFICER, DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Programmatic Changes and Budget...

  16. Anomalies of Nuclear Criticality, Revision 6

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, E. D.; Prichard, Andrew W.; Durst, Bonita E.; Erickson, David; Puigh, Raymond J.

    2010-02-19

    This report is revision 6 of the Anomalies of Nuclear Criticality. This report is required reading for the training of criticality professionals in many organizations both nationally and internationally. This report describes many different classes of nuclear criticality anomalies that are different than expected.

  17. Revised Reynolds Stress and Triple Product Models

    Science.gov (United States)

    Olsen, Michael E.; Lillard, Randolph P.

    2017-01-01

    Revised versions of Lag methodology Reynolds-stress and triple product models are applied to accepted test cases to assess the improvement, or lack thereof, in the prediction capability of the models. The Bachalo-Johnson bump flow is shown as an example for this abstract submission.

  18. 36 CFR 219.9 - Revision.

    Science.gov (United States)

    2010-07-01

    ... Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.9 Revision. (a) Application... is a review of the overall management of a unit of the National Forest System and an opportunity...

  19. Revised Safety Instruction 4 (IS4 REV.)

    CERN Multimedia

    2006-01-01

    Please note that the revised safety instruction 4 (IS4 REV.) entitled 'Safety Inspections' is available on the web at the following url: https://edms.cern.ch/file/335741/LAST_RELEASED/E_IS4.pdf Paper copies can also be obtained from the SC unit secretariat, e-mail: sc.secretariat@cern.ch SC Secretariat

  20. A taxonomic revision of the Hypnodendraceae (Musci)

    NARCIS (Netherlands)

    Touw, A.

    1971-01-01

    A revision is made of the genera Hypnodendron and Braithwaitea. Mniodendron and Sciadocladus are reduced to Hypnodendron, Limbella is excluded from the Hypnodendraceae, and Dendro-Hypnum is considered to be not validly published. Hypnodendron rigidum Mitt. is transferred to Pterobryella. The species

  1. Fast-track revision knee arthroplasty

    DEFF Research Database (Denmark)

    Husted, Henrik; Otte, Niels Kristian Stahl; Kristensen, Billy B;

    2011-01-01

    Abstract Background and purpose Fast-track surgery has reduced the length of hospital stay (LOS), morbidity, and convalescence in primary hip and knee arthroplasty (TKA). We assessed whether patients undergoing revision TKA for non-septic indications might also benefit from fast-track surgery...

  2. Metal ion levels and revision rates in metal-on-metal hip resurfacing arthroplasty: a comparative study.

    Science.gov (United States)

    Robinson, Patrick G; Wilkinson, Andrew J; Meek, Robert M D

    2014-01-01

    Metal-on-metal (MoM) bearings in hip surgery are related to increased blood levels of metal ions. The nature of the relationship between ion levels and failure is still not fully understood. This study compares three cohorts of patients, 120 patients in each cohort, treated with a hip resurfacing arthroplasty, grouped by brand and diameter of femoral component on average four years postoperatively: Birmingham Hip Resurfacing ≥50 mm, Durom resurfacing ≥50 mm and Durom resurfacing resurfacing than the other two cohorts (P<0.05). The large BHR and large Durom HRA had revision rates of 3.3%. The small Durom HRA had a revision rate of 8.3%. Elevated blood ion levels can indicate a failing MoM bearing. The large BHR and large Durom HRA have similar revision rates yet the large Durom HRA had significantly lower metal ion levels. When similar ion levels were reported for BHR and small Durom the latter had significantly higher revision rates. This suggests ion levels do not absolutely predict the rate of HRA failure. Since MoM generation of metal ions is not the sole reason of failure, regular clinical and radiographic follow-up should also be in place for patients with these joints.

  3. [The study on the establishment of acupuncture].

    Science.gov (United States)

    Jung, Woojin

    2011-12-31

    In ancient china, four famous literatures, Huang Di Nei Jing, Nan Jing, Ben Cao, Shang Han Lun appeared, which made the foundation of oriental medicine. Huang Di Nei Jing, the book of acupuncture, is the most essential literature among these four litertures. So the question asking the identity of oriental medicine can be turned into the question about the identity of acupuncture. The investigation into origin will not be the only way to study of identity but one of the most attractive means. So we can answer with the study of origin to the question about identity. Acupuncture is comprised of theories like jing mai, qi xue and technical factors like moxibustion, bian which is like present operating knife. To trace the origin of acupuncture, we must investigate not only technical factors but also theories. But it will be impossible to trace every theories underlying the acupuncture in this small thesis. This is the reason that I restricted my attention to the principle of preventive medicine, regimen. Before the excavation of Mawangdui, the belief that acupuncture started long ago before Han period had been generally accepted. But there was not any proof proving the presence of acupuncture in the excavated literatures representing the Han period medicine. This fact announced that we must draw the time of establishment of acupuncture back after the Mawangdui literature buried in B.C. 168. But we can find the proof of the presence of acupuncture just before B.C. 168 in Shiji written by Si Mi Qian. Through these facts and inferences that we got until now, we can reach a conclusion that acupuncture would have appeared around 190-176 when Chun Yu Yi was practicing as a doctor. As you know, in the Mawangdui literature, what was associated with jing mai was moxibustion. But at the same time, moxibustion was being used just as the experience medicine technique without theory. So the moxibustion would has been about to be associated with jing mai theory in Mawangdui period

  4. Effect of perioperative blood transfusions on long term graft outcomes in renal transplant patients.

    LENUS (Irish Health Repository)

    O'Brien, Frank J

    2012-06-01

    It is established that blood transfusions will promote sensitization to human leucocyte antigen (HLA) antigens, increase time spent waiting for transplantation and may lead to higher rates of rejection. Less is known about how perioperative blood transfusion influence patient and graft outcome. This study aims to establish if there is an association between perioperative blood transfusion and graft or patient survival.

  5. Radiological findings in patients undergoing revision endoscopic sinus surgery: a retrospective case series study

    Directory of Open Access Journals (Sweden)

    Eweiss Ahmed Z

    2011-05-01

    Full Text Available Abstract Background Functional endoscopic sinus surgery (FESS is now a well-established strategy for the treatment of chronic rhinosinusitis which has not responded to medical treatment. There is a wide variation in the practice of FESS by various surgeons within the UK and in other countries. Objectives To identify anatomic factors that may predispose to persistent or recurrent disease in patients undergoing revision FESS. Methods Retrospective review of axial and coronal CT scans of patients undergoing revision FESS between January 2005 and November 2008 in a tertiary referral centre in South West of England. Results The CT scans of 63 patients undergoing revision FESS were reviewed. Among the patients studied, 15.9% had significant deviation of the nasal septum. Lateralised middle turbinates were present in 11.1% of the studied sides, and residual uncinate processes were identified in 57.1% of the studied sides. There were residual cells in the frontal recess in 96% of the studied sides. There were persistent other anterior and posterior ethmoidal cells in 92.1% and 96% of the studied sides respectively. Conclusions Analysis of CT scans of patients undergoing revision FESS shows persistent structures and non-dissected cells that may be responsible for persistence or recurrence of rhinosinusitis symptoms. Trials comparing the outcome of conservative FESS techniques with more radical sinus dissections are required.

  6. Technical support document for proposed 1994 revision of the MEC thermal envelope requirements

    Energy Technology Data Exchange (ETDEWEB)

    Conner, C.C.; Lucas, R.G.

    1994-03-01

    This report documents the development of the proposed revision of the Council of American Building Officials` (CABO) 1994 supplement to the 1993 Model Energy Code (MEC) building thermal envelope requirements for maximum component U{sub 0}-value. The 1994 amendments to the 1993 MEC were established in last year`s code change cycle and did not change the envelope requirements. The research underlying the proposed MEC revision was conducted by Pacific Northwest Laboratory (PNL) for the US Department of Energy (DOE) Building Energy Standards program. The goal of this research was to develop revised guidelines based on an objective methodology that determines the most cost-effective (least total cost) combination of energy conservation measures (ECMs) (insulation levels and window types) for residential buildings. This least-cost set of ECMs was used as a basis for proposing revised MEC maximum U{sub 0}-values (thermal transmittances). ECMs include window types (for example, double-pane vinyl) and insulation levels (for example, R-19) for ceilings, walls, and floors.

  7. Medical Examination of Aliens--Revisions to Medical Screening Process. Final rule.

    Science.gov (United States)

    2016-01-26

    The Centers for Disease Control and Prevention (CDC), within the Department of Health and Human Services (HHS), is issuing this final rule (FR) to amend its regulations governing medical examinations that aliens must undergo before they may be admitted to the United States. Based on public comment received, HHS/CDC did not make changes from the NPRM published on June 23, 2015. Accordingly, this FR will: Revise the definition of communicable disease of public health significance by removing chancroid, granuloma inguinale, and lymphogranuloma venereum as inadmissible health-related conditions for aliens seeking admission to the United States; update the notification of the health-related grounds of inadmissibility to include proof of vaccinations to align with existing requirements established by the Immigration and Nationality Act (INA); revise the definitions and evaluation criteria for mental disorders, drug abuse and drug addiction; clarify and revise the evaluation requirements for tuberculosis; clarify and revise the process for the HHS/CDC-appointed medical review board that convenes to reexamine the determination of a Class A medical condition based on an appeal; and update the titles and designations of federal agencies within the text of the regulation.

  8. Establishing Time for Professional Learning

    Science.gov (United States)

    Journal of Staff Development, 2013

    2013-01-01

    Time for collaborative learning is an essential resource for educators working to implement college- and career-ready standards. The pages in this article include tools from the workbook "Establishing Time for Professional Learning." The tools support a complete process to help educators effectively find and use time. The following…

  9. The Establishment of a Comprehensive High School Renewal Site in the Erie, Pa. Public Schools. Maxi II Practicum.

    Science.gov (United States)

    Cianflocco, Sam C.

    This practicum report describes in detail the efforts of a High School Task Force made up of 21 teachers to establish and operate a model high school as part of a new 4-4-4 educational plan for the Erie, Pennsylvania, schools. The Strong Vincent Comprehensive High School Renewal Site utilized curriculum revision, quarter course offerings, and…

  10. 30 CFR 285.617 - What activities require a revision to my SAP, and when will MMS approve the revision?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities require a revision to my SAP... OUTER CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 285.617 What activities require a revision to my SAP, and when will MMS approve the revision? (a) You...

  11. A study on the establishment of component/equipment performance criteria considering Heavy Water Reactor characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Keun Sun; Kwon, Young Chul; Lee, Min Kyu; Lee, Yun Soo [Sunmoon Univ., Asan (Korea, Republic of); Chang, Seong Hoong; Ryo, Chang Hyun [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Kim, Soong Pyung; Hwnag, Jung Rye; Chung, Chul Kee [Chosun Univ., Gwangju (Korea, Republic of)

    2002-03-15

    Foreign and domestic technology trends, regulatory requirements, design and researches for heavy water reactors are analyzed. Safety design guides of Canada industry and regulatory documents and consultative documents of Canada regulatory agency are reviewed. Applicability of MOST guidance 16 Revision 'guidance for technical criteria of nuclear reactor facility' is reviewed. Specific performance criteria are established for components and facilities for heavy water reactor.

  12. Women, Hypertension, and the Systolic Blood Pressure Intervention Trial.

    Science.gov (United States)

    Wenger, Nanette K; Ferdinand, Keith C; Bairey Merz, C Noel; Walsh, Mary Norine; Gulati, Martha; Pepine, Carl J

    2016-10-01

    Hypertension accounts for approximately 1 in 5 deaths in American women and is the major contributor to many comorbid conditions. Although blood pressure lowering reduces cardiovascular disease outcomes, considerable uncertainty remains on best management in women. Specifically, female blood pressure treatment goals have not been established, particularly among older and African American and Hispanic women, for whom hypertension prevalence, related adverse outcomes, and poor control rates are high. The Systolic Blood Pressure Intervention Trial (SPRINT) planned to clarify optimal blood pressure management in both sexes. Although confirming that a lower blood pressure goal is generally better, because female enrollment and event rates were low and follow-up shortened, outcomes differences in women were not statistically significant. Thus optimal blood pressure goals for women have not been established with the highest evidence. This review addresses SPRINT's significance and key remaining knowledge gaps in optimal blood pressure management to improve women's health.

  13. Red blood cell alloimmunization after blood transfusion

    NARCIS (Netherlands)

    Schonewille, Henk

    2008-01-01

    Current pretransfusion policy requires the patients’ serum to be tested for the presence of irregular red blood cell antibodies. In case of an antibody, red blood cells lacking the corresponding antigen are transfused after an antiglobulin crossmatch. The aim of the studies in this thesis is primari

  14. PARTICULARITIES REGARDING THE ESTABLISHMENT OF

    Directory of Open Access Journals (Sweden)

    NAGY CRISTINA MIHAELA

    2013-05-01

    Full Text Available Commercial companies from the insurance field have, under the law, features that distinguish them from other commercial companies in respect of the establishment and the company's operation and control. For insurance companies there is a unique authorization system, by the member state in which their head office is located (home member state, and based on this authorization they can carry out insurance activities in any member states by opening agencies or subsidiaries, with prior notification to the ISC by the authorities of those States. Apparently the number of documents required to establish a company in the insurance sector is large and the stages are laborious but necessary because the State has to act prudentially as insurance services are addressed to natural or legal persons potentially vulnerable.

  15. Move two: establishing a niche

    Directory of Open Access Journals (Sweden)

    Wasima Shehzad

    2008-04-01

    Full Text Available The significant purpose of the author in the Introduction of a research article is to convince the reader about the importance of the work to be presented. To achieve this end, a convincing “niche” needs to be built by evaluating, rejecting or indicating gaps in previous related work. The purpose of “establishing a niche” is to emphasize the current research project presented by the author. The present paper investigates how Computer scientists use this obligatory step of “Create a Research Space” (CARS model (Swales & Feak, 1994 & 2004 to highlight their own research work. This paper not only compares the results with other similar studies but also presents an in-depth analysis of various types of gap statements used in Computer Science research article Introductions. The issue of cyclicity of this step and the linguistic indicators used for the establishment of “niche” (the gap statements are both discussed.

  16. Factors affecting forage stand establishment

    Directory of Open Access Journals (Sweden)

    Sulc R.M.

    1998-01-01

    Full Text Available Significant advances have been made in our knowledge of forage seed physiology, technology, and stand establishment practices; however, stand establishment continues to be one of the most common production problems affecting forage crops in the USA. There is a need for research on stand establishment of forage crops under abiotic and biotic stress. Although the forage seed industry produces and markets seed of high quality, new methods of assessing seed vigor are needed and their use should be expanded in the industry to enable matching seed lot performance to specific environmental conditions where performance can be maximized. Seed treatment and seed coating are used in the forage seed industry, and studies have shown they are of benefit in some environments. There is an increase in no-tillage seeding of forage crops, but improvements in the no-tillage planting equipment are needed to make them better suited to small seeds. Other recent developments in seeding techniques include broadcasting seed with dry granular and fluid fertilizers, which improves the efficiency of the seeding operation.

  17. Treatment of Established Status Epilepticus

    Science.gov (United States)

    Falco-Walter, Jessica J.; Bleck, Thomas

    2016-01-01

    Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE)) is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT). Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus), elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE. PMID:27120626

  18. Treatment of Established Status Epilepticus

    Directory of Open Access Journals (Sweden)

    Jessica J. Falco-Walter

    2016-04-01

    Full Text Available Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT. Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus, elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE.

  19. [Revision arthroplasty of the ankle joint].

    Science.gov (United States)

    Hintermann, B; Barg, A; Knupp, M

    2011-11-01

    In the last 20 years total ankle replacement has become a viable alternative to arthrodesis for end-stage osteoarthritis of the ankle. Numerous ankle prosthesis designs have appeared on the market in the past and attracted by the encouraging intermediate results reported in the literature, many surgeons have started to perform this procedure. With increased availability on the market the indications for total ankle replacement have also increased in recent years. In particular, total ankle replacement may now be considered even in younger patients. Therefore, despite progress in total ankle arthroplasty the number of failures may increase. Up to now, arthrodesis was considered to be the gold standard for salvage of failed ankle prostheses. Because of extensive bone loss on the talar side, in most instances tibiocalcaneal fusion is the only reliable solution. An alternative to such extended hindfoot fusions would be revision arthroplasty. To date, however, there are no reported results of revision arthroplasty for salvage of a failed ankle replacement.Based on our experience prosthetic components with a flat undersurface are most likely to be able to find solid support on remaining bone stock. The first 83 cases (79 patients, 46 males, 33 females, average age 58.9 years, range 30.6-80.7 years) with a average follow-up of 5.4 years (range 2-11 years) showed excellent to good results in 69 cases (83%), a satisfactory result in 12 cases (15%) and a fair result in 2 cases (2%) and 47 patients (56%) were pain free. Primary loosening was noted in three cases and of these two cases were successfully revised by another total ankle replacement and in one case with arthrodesis. Another case with hematogenous infection was also revised by arthrodesis. At the last follow-up control two components were considered to be loose and the overall loosening rate was thus 6%.This series has proven that revision arthroplasty can be a promising option for patients with failed total

  20. Supply and demand of bone allograft for revision hip surgery in Scotland.

    Science.gov (United States)

    Galea, G; Kopman, D; Graham, B J

    1998-07-01

    The Scottish National Blood Transfusion Service is the main provider of bone for grafting in Scotland. Bone is procured only from live donors, following very strict selection criteria, and we have investigated whether the amount being collected was adequate. Our current harvest of approximately 1700 femoral heads per year is shown not to be enough to meet the future demand for revision surgery of the hip. Many more of these operations are being undertaken, and impaction grafting is being used increasingly. We have calculated the predicted rates of collection and usage for the next four to five years so that we can expand our service in a controlled fashion.

  1. Genetics Blood Card Use

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — SOP guiding collection of blood for genetics analysis. Provides stepwise instructions and guidance on how to collect DNA sample using a whole blood blot card

  2. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... known as venous thromboembolism, are highly preventable (see prevention tips below). The U.S. Surgeon General has issued ... blood conditions and increase research on the causes, prevention, and treatment. Blood clots are also potentially dangerous ...

  3. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... pregnancy: Be aware of risk factors. Know your family history. Make sure your doctor knows about any ... blood clots or blood clotting disorders in your family. Remain active, with your doctor's approval. Be aware ...

  4. Chloride test - blood

    Science.gov (United States)

    ... disease Antidiuretic hormone blood test Gastric suction Heart failure - overview Hyperventilation Ions Metabolic acidosis Multiple endocrine neoplasia (MEN) II Proximal renal tubular acidosis Respiratory acidosis Sodium blood test Review Date 5/3/2015 Updated by: Laura J. ...

  5. High blood pressure medications

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007484.htm High blood pressure medicines To use the sharing features on this page, please enable JavaScript. Treating high blood pressure will help prevent problems such as heart disease, ...

  6. Blood Pressure Medicines

    Science.gov (United States)

    High blood pressure, also called hypertension, usually has no symptoms. But it can cause serious problems such as stroke, ... kidney failure. If you cannot control your high blood pressure through lifestyle changes such as losing weight ...

  7. White Blood Cell Disorders

    Science.gov (United States)

    ... Fundamentals Heart and Blood Vessel Disorders Hormonal and Metabolic Disorders Immune Disorders Infections Injuries and Poisoning Kidney and ... Fundamentals Heart and Blood Vessel Disorders Hormonal and Metabolic Disorders Immune Disorders Infections Injuries and Poisoning Kidney and ...

  8. Low blood sugar - newborns

    Science.gov (United States)

    ... medlineplus.gov/ency/article/007306.htm Low blood sugar - newborns To use the sharing features on this page, please enable JavaScript. A low blood sugar level in newborn babies is also called neonatal ...

  9. Blood Transfusions (For Teens)

    Science.gov (United States)

    ... many precautions to confirm a patient's and donor's blood are compatible before giving a transfusion. In almost every situation, the benefits of having a blood transfusion far outweigh the risks. The Red Cross ...

  10. High blood cholesterol levels

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000403.htm High blood cholesterol levels To use the sharing features ... stroke, and other problems. The medical term for high blood cholesterol is lipid disorder, hyperlipidemia, or hypercholesterolemia. ...

  11. Yakima Fisheries Project : Revised Draft Environmental Impact Statement.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1995-05-01

    BPA proposes to fund several fishery-related activities in the Yakima River Basin. The Yakima Fisheries Project (YFP), included in the Northwest Power Planning Council`s fish and wildlife program, would be jointly managed by the State of Washington and the Yakima Indian Nation. Fisheries resources in the Yakima River are severely reduced from historical levels and there is a significant potential for enhancement of these resources. BPA`s proposed action is to fund (1) information gathering on the implementation of supplementation techniques and on feasibility of reintroducing coho salmon in an environment where native populations have become extinct; (2) research activities based on continuous assessment, feedback and improvement of research design and activities ({open_quotes}adaptive management{close_quotes}); and (3) the construction, operation, and maintenance of facilities for supplementing populations of upper Yakima spring chinook salmon. The project has been considerably revised from the original proposal described in the first draft EIS. Examined in addition to No Action (which would leave present anadromous fisheries resources unchanged in the, Basin) are two alternatives for action: (1) supplementation of depressed natural populations of upper Yakima spring chinook and (2) that same supplementation plus a study to determine the feasibility of re-establishing (via stock imported from another basin) naturally spawning population and a significant fall fishery for coho in the Yakima Basin. Alternative 2 has been identified as the preferred action. Major issues examined in the Revised Draft EIS include potential impacts of the project on genetic and ecological resources of existing fish populations, on water quality and quantity, on threatened and endangered species listed under the Endangered Species Act, and on the recreational fishery.

  12. Battery Test Manual For Electric Vehicles, Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Christophersen, Jon P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-06-01

    This battery test procedure manual was prepared for the United States Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), Vehicle Technologies Office. It is based on technical targets for commercial viability established for energy storage development projects aimed at meeting system level DOE goals for Electric Vehicles (EV). The specific procedures defined in this manual support the performance and life characterization of advanced battery devices under development for EVs. However, it does share some methods described in the previously published battery test manual for plug-in hybrid electric vehicles. Due to the complexity of some of the procedures and supporting analysis, future revisions including some modifications and clarifications of these procedures are expected. As in previous battery and capacitor test manuals, this version of the manual defines testing methods for full-size battery systems, along with provisions for scaling these tests for modules, cells or other subscale level devices. The DOE-United States Advanced Battery Consortium (USABC), Technical Advisory Committee (TAC) supported the development of the manual. Technical Team points of contact responsible for its development and revision are Chul Bae of Ford Motor Company and Jon P. Christophersen of the Idaho National Laboratory. The development of this manual was funded by the Unites States Department of Energy, Office of Energy Efficiency and Renewable Energy, Vehicle Technologies Office. Technical direction from DOE was provided by David Howell, Energy Storage R&D Manager and Hybrid Electric Systems Team Leader. Comments and questions regarding the manual should be directed to Jon P. Christophersen at the Idaho National Laboratory (jon.christophersen@inl.gov).

  13. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

    Science.gov (United States)

    Hodges, John R.; Knopman, David; Mendez, Mario F.; Kramer, Joel H.; Neuhaus, John; van Swieten, John C.; Seelaar, Harro; Dopper, Elise G. P.; Onyike, Chiadi U.; Hillis, Argye E.; Josephs, Keith A.; Boeve, Bradley F.; Kertesz, Andrew; Seeley, William W.; Rankin, Katherine P.; Johnson, Julene K.; Gorno-Tempini, Maria-Luisa; Rosen, Howard; Prioleau-Latham, Caroline E.; Lee, Albert; Kipps, Christopher M.; Lillo, Patricia; Piguet, Olivier; Rohrer, Jonathan D.; Rossor, Martin N.; Warren, Jason D.; Fox, Nick C.; Galasko, Douglas; Salmon, David P.; Black, Sandra E.; Mesulam, Marsel; Weintraub, Sandra; Dickerson, Brad C.; Diehl-Schmid, Janine; Pasquier, Florence; Deramecourt, Vincent; Lebert, Florence; Pijnenburg, Yolande; Chow, Tiffany W.; Manes, Facundo; Grafman, Jordan; Cappa, Stefano F.; Freedman, Morris; Grossman, Murray; Miller, Bruce L.

    2011-01-01

    Based on the recent literature and collective experience, an international consortium developed revised guidelines for the diagnosis of behavioural variant frontotemporal dementia. The validation process retrospectively reviewed clinical records and compared the sensitivity of proposed and earlier criteria in a multi-site sample of patients with pathologically verified frontotemporal lobar degeneration. According to the revised criteria, ‘possible’ behavioural variant frontotemporal dementia requires three of six clinically discriminating features (disinhibition, apathy/inertia, loss of sympathy/empathy, perseverative/compulsive behaviours, hyperorality and dysexecutive neuropsychological profile). ‘Probable’ behavioural variant frontotemporal dementia adds functional disability and characteristic neuroimaging, while behavioural variant frontotemporal dementia ‘with definite frontotemporal lobar degeneration’ requires histopathological confirmation or a pathogenic mutation. Sixteen brain banks contributed cases meeting histopathological criteria for frontotemporal lobar degeneration and a clinical diagnosis of behavioural variant frontotemporal dementia, Alzheimer’s disease, dementia with Lewy bodies or vascular dementia at presentation. Cases with predominant primary progressive aphasia or extra-pyramidal syndromes were excluded. In these autopsy-confirmed cases, an experienced neurologist or psychiatrist ascertained clinical features necessary for making a diagnosis according to previous and proposed criteria at presentation. Of 137 cases where features were available for both proposed and previously established criteria, 118 (86%) met ‘possible’ criteria, and 104 (76%) met criteria for ‘probable’ behavioural variant frontotemporal dementia. In contrast, 72 cases (53%) met previously established criteria for the syndrome (P < 0.001 for comparison with ‘possible’ and ‘probable’ criteria). Patients who failed to meet revised

  14. Bicyclic graphs with maximal revised Szeged index

    CERN Document Server

    Li, Xueliang

    2011-01-01

    The revised Szeged index $Sz^*(G)$ is defined as $Sz^*(G)=\\sum_{e=uv \\in E}(n_u(e)+ n_0(e)/2)(n_v(e)+ n_0(e)/2),$ where $n_u(e)$ and $n_v(e)$ are, respectively, the number of vertices of $G$ lying closer to vertex $u$ than to vertex $v$ and the number of vertices of $G$ lying closer to vertex $v$ than to vertex $u$, and $n_0(e)$ is the number of vertices equidistant to $u$ and $v$. Hansen used the AutoGraphiX and made the following conjecture about the revised Szeged index for a connected bicyclic graph $G$ of order $n \\geq 6$:

  15. Rh Factor Blood Test

    Science.gov (United States)

    Tests and Procedures Rh factor blood test By Mayo Clinic Staff Rhesus (Rh) factor is an inherited protein found on the surface of ... If your blood has the protein, you're Rh positive. If your blood lacks the protein, you' ...

  16. High Blood Pressure Facts

    Science.gov (United States)

    ... More black women than men have high blood pressure. 2 Race of Ethnic Group Men (%) Women (%) African Americans 43.0 45.7 Mexican Americans 27.8 28.9 Whites 33.9 31.3 All 34.1 32.7 Top of Page Why Blood Pressure Matters View this graphic snapshot of blood pressure ...

  17. Food miles to assess sustainability: A revision

    OpenAIRE

    VAN PASSEL, Steven

    2013-01-01

    Sustainability assessment is an essential process in our aim to reach a more sustainable production and consumption pattern. This research revises the food miles concept as a guiding tool to assess sustainability. Food miles measure the distance that food travels from where it is grown or raised to where it is consumed. Three different concepts to assess sustainability are described: (i) food miles, (ii) enhanced food miles, (iii) food chain sustainability. An illustrative case study shows th...

  18. Benchmarking i eksternt regnskab og revision

    DEFF Research Database (Denmark)

    Thinggaard, Frank; Kiertzner, Lars

    2001-01-01

    løbende i en benchmarking-proces. Dette kapitel vil bredt undersøge, hvor man med nogen ret kan få benchmarking-begrebet knyttet til eksternt regnskab og revision. Afsnit 7.1 beskæftiger sig med det eksterne årsregnskab, mens afsnit 7.2 tager fat i revisionsområdet. Det sidste afsnit i kapitlet opsummerer...... betragtningerne om benchmarking i forbindelse med begge områder....

  19. Heel pain-plantar fasciitis: revision 2014.

    Science.gov (United States)

    Martin, Robroy L; Davenport, Todd E; Reischl, Stephen F; McPoil, Thomas G; Matheson, James W; Wukich, Dane K; McDonough, Christine M

    2014-11-01

    The Orthopaedic Section of the American Physical Therapy Association (APTA) has an ongoing effort to create evidence-based practice guidelines for orthopaedic physical therapy management of patients with musculoskeletal impairments described in the World Health Organization's International Classification of Functioning, Disability, and Health (ICF). The purpose of these revised clinical practice guidelines is to review recent peer-reviewed literature and make recommendations related to nonarthritic heel pain.

  20. Revision of ISO 15859 Aerospace Fluid Standards

    Science.gov (United States)

    Greene, Benjamin; McClure, Mark B.

    2012-01-01

    A detailed review of ISO 15859 "Space Systems - Fluid Characteristics, Sampling and Test Methods" was performed An approach to revising Parts 1-9 and 11-13 was developed and concurred by the NASA Technical Standards Program Office. The approach was to align them with the highest level source documents, and not to program-specific requirements. The updated documents were prepared and presented.

  1. Clinical Outcomes Following Revision Anterior Shoulder Stabilization

    Science.gov (United States)

    Frank, Rachel M.; Mellano, Chris; Shin, Jason J.; Feldheim, Terrence F.; Mascarenhas, Randhir; Yanke, Adam Blair; Cole, Brian J.; Nicholson, Gregory P.; Romeo, Anthony A.; Verma, Nikhil N.

    2015-01-01

    Objectives: The purpose of this study was to determine the clinical outcomes following revision anterior shoulder stabilization performed either via all-arthroscopic soft tissue repair or via Latarjet coracoid transfer. Methods: A retrospective review of prospectively collected data on 91 shoulders undergoing revision anterior shoulder stabilization was performed. All patients underwent prior soft tissue stabilization; those with prior open bone grafting procedures were excluded. For patients with 25% glenoid bone loss, Latarjet was performed (n=28). Patients were queried regarding recurrent instability (subluxation or dislocation). Clinical outcomes were evaluated using validated patient reported outcome questionnaires including the American Shoulder and Elbow Surgeons (ASES) score, Simple Shoulder Test (SST), visual analog scale (VAS) for pain, and Western Ontario Shoulder Instability Index (WOSI). Results: A total of 63 shoulders in 62 patients (46 males, 16 females) with an average age of 23.2 ± 6.9 years were included in the revision arthroscopy group. At an average follow-up of 46.9 ± 16.8 months (range, 15 to 78), the mean WOSI score was 80.1 (range, 15.0 to 100), and there were significant improvements (pLatarjet group. Thirteen (46%) had more than one previous stabilization attempt. ), the average WOSI score was 71.9, and there were significant improvements (pLatarjet. Conclusion: Both arthroscopic revision stabilization and Latarjet coracoid transfer result in satisfactory outcomes in patients who have failed previous arthroscopic capsulolabral repair. Recurrent instability rates were higher in the all-arthroscopic group (19% versus 7%). Longer-term studies are required to determine whether similar results are maintained over time, and to provide guidance on focused clinical indications for this challenging patient population.

  2. Revised Safety Instruction 41 (IS41 REV.)

    CERN Multimedia

    SC Secretariat

    2005-01-01

    Please note that the Revised Safety Instruction No. 41 (IS41 REV.), entitled 'The use of plastic and other non-metallic materials at CERN with respect to fire safety and radiation resistance' is available on the web at the following url: https://edms.cern.ch/document/335806/LAST_RELEASED Paper copies can also be obtained from the SC Unit Secretariat, e-mail: sc.secretariat@cern.ch SC Secretariat

  3. Cord blood transplantation: can we make it better?

    Directory of Open Access Journals (Sweden)

    Leland eMetheny

    2013-09-01

    Full Text Available Umbilical cord blood is an established source of hematopoietic stem cells for transplantation. It enjoys several advantages over bone marrow or peripheral blood, including increased tolerance for Human Leukocyte Antigen mismatches, decreased incidence of graft-versus-host disease, and easy availability. Unrelated cord blood does have limitations, however, especially in the treatment of adults. In the 24 years since the first umbilical cord blood transplant was performed, significant progress has been made, but delayed hematopoietic engraftment and increased treatment related mortality remain obstacles to widespread use. Here we summarize the latest results of unrelated cord blood transplants, and review strategies under investigation to improve clinical outcomes.

  4. A well-established profession

    DEFF Research Database (Denmark)

    Braae, Ellen Marie; Hare, Richard Andrew

    2011-01-01

    It was during the economic boom of the 1960s that the demand for landscape architects began to explode in Denmark as the expanding welfare state brought about rapid physical changes. At this time the country’s first specific education for landscape architects was established and 2010 marked the 5......th anniversary of landscape architecture teaching, at the Faculty of Life Science – the University of Copenhagen(KU-Life). It’s origins can be traced further back but, then as now, the essence of the education is that of creating a dynamic synergy of the sciences and the arts....

  5. US FDA's revised consumption factor for polystyrene used in food-contact applications.

    Science.gov (United States)

    Cassidy, K; Elyashiv-Barad, S

    2007-09-01

    US FDA's continual effort to evaluate the safety of food-contact materials includes periodically re-examining our established packaging factors, such as consumption and food-type distribution factors. The use of polystyrene in food-contact and disposable food-packaging applications has expanded and is expected to continue to increase in the future. Therefore, it is important to revise the polystyrene consumption factor to account for increases in consumer exposure to substances migrating from styrenic food packaging. The currently used consumption factor for polystyrene is 0.1, which is based on market data collected around 1980. US FDA has revised the polystyrene consumption factor utilizing three different sources of market data. Using consumption and population data, US FDA calculated a new consumption factor of 0.14 for polystyrene. This consumption factor has been further subdivided to allow for the refinement of exposure estimates for uses limited to specific subcategories of polystyrene packaging.

  6. Revision of the energy conservation requirements in the manufactured home construction and safety standards

    Energy Technology Data Exchange (ETDEWEB)

    Conner, C C; Lee, A D; Lucas, R G; Taylor, Z T

    1992-02-01

    Thermal requirements were developed for manufactured (mobile) homes in response to legislation requiring the US Department of Housing and Urban Development (HUD) to revise its thermal standards for manufactured homes. A life-cycle cost minimization from the home owner's perspecetive was used to establish an optimum in a large number of cities for several prototype homes. The development of the economic, financial, and energy conservation measure parameters input into the life-cycle cost analysis was documented. The optimization results were aggregated to zones which were expressed as a maximum overall home U-value (thermal transmittance) requirement. The revised standard's costs, benefits, and net value to the consumer were quantified. 50 refs.

  7. Establishing nuclear facility drill programs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The purpose of DOE Handbook, Establishing Nuclear Facility Drill Programs, is to provide DOE contractor organizations with guidance for development or modification of drill programs that both train on and evaluate facility training and procedures dealing with a variety of abnormal and emergency operating situations likely to occur at a facility. The handbook focuses on conducting drills as part of a training and qualification program (typically within a single facility), and is not intended to included responses of personnel beyond the site boundary, e.g. Local or State Emergency Management, Law Enforcement, etc. Each facility is expected to develop its own facility specific scenarios, and should not limit them to equipment failures but should include personnel injuries and other likely events. A well-developed and consistently administered drill program can effectively provide training and evaluation of facility operating personnel in controlling abnormal and emergency operating situations. To ensure the drills are meeting their intended purpose they should have evaluation criteria for evaluating the knowledge and skills of the facility operating personnel. Training and evaluation of staff skills and knowledge such as component and system interrelationship, reasoning and judgment, team interactions, and communications can be accomplished with drills. The appendices to this Handbook contain both models and additional guidance for establishing drill programs at the Department`s nuclear facilities.

  8. Cancer and blood coagulation.

    Science.gov (United States)

    Boccaccio, C; Medico, E

    2006-05-01

    In human patients, blood coagulation disorders often associate with cancer, even in its early stages. Recently, in vitro and in vivo experimental models have shown that oncogene expression, or inactivation of tumour suppressor genes, upregulate genes that control blood coagulation. These studies suggest that activation of blood clotting, leading to peritumoral fibrin deposition, is instrumental in cancer development. Fibrin can indeed build up a provisional matrix, supporting the invasive growth of neoplastic tissues and blood vessels. Interference with blood coagulation can thus be considered as part of a multifaceted therapeutic approach to cancer.

  9. Laparoscopy for ventriculoperitoneal shunt implantation and revision surgery

    Institute of Scientific and Technical Information of China (English)

    Fernando; Campos; Gomes; Pinto; Matheus; Fernandes; de; Oliveira

    2014-01-01

    Ventriculoperitoneal shunting(VPS) is a widely accepted technique for the treatment of hydrocephalus. The probability of shunt dysfunction is pretty high throughout life. Laparoscopy has become a valuable tool to perform VPS and treat abdominal complications. An electronic literature search was performed to reveal the published data relating laparoscopy and ventriculoperitoneal shunt in Medline, Embase, Scielo and Lilacs databases. The keywords employed were “laparoscopy” OR “laparoscopic surgery” AND “ventriculoperitoneal shunt” OR “shunt” AND “surgery” OR “implantation” OR “revision” OR “complication”. No high quality trials were developed comparing conventional laparotomic incision vs laparoscopic approach. Both approaches have evolved and currently there are less invasive options for laparotomy, like periumbilical small incisions; and for laparoscopy, like smaller and less incisions. Operating room time, blood loss and hospital stay may be potentially smaller in laparoscopic surgery and complications are probably the same as laparotomy. In revision surgery for abdominal complications after VPS,visualization of whole abdominal cavity is fundamental to address properly the problem and laparoscopic approach is valuable once it is safe, fast and much less invasive than laparotomy. Ventriculoperitoneal shunting is a widely accepted technique for the treatment of hydrocephalus. Laparoscopy assisted shunt surgery in selected cases might be a less invasive and more effective option for intrabdominal manipulation. The laparoscopic approach allows a better catheter positioning, lysis of fibrotic bundles and peritoneal inspection as well, without any additional complication.

  10. Blood groups systems

    Directory of Open Access Journals (Sweden)

    Ranadhir Mitra

    2014-01-01

    Full Text Available International Society of Blood Transfusion has recently recognized 33 blood group systems. Apart from ABO and Rhesus system, many other types of antigens have been noticed on the red cell membranes. Blood grouping and cross-matching is one of the few important tests that the anaesthesiologist orders during perioperative period. Hence, a proper understanding of the blood group system, their clinical significance, typing and cross-matching tests, and current perspective are of paramount importance to prevent transfusion-related complications. Nonetheless, the knowledge on blood group system is necessary to approach blood group-linked diseases which are still at the stage of research. This review addresses all these aspects of the blood groups system.

  11. Blood pressure circadian rhythm and obesity: Blood pressure variations and obesity

    Directory of Open Access Journals (Sweden)

    Despotović Nebojša

    2002-01-01

    Full Text Available Introduction The association between obesity and arterial hypertension has been established in a great number of studies. Our objective was to investigate whether circadian rhythm of blood pressure is disturbed among obese people. Material and methods In this cross-sectional, randomized study, Schiller BR-102 device was used for ambulatory blood pressure monitoring. One hundred and twenty outpatients were divided into three randomized groups: obese body mass index 30 kg/m2 (52 patients, overweight (28 patients, with body mass index 25,0-29,9 kg/m2 and normal weight (control group (48 patients, with body mass index 18,5-24,9 kg/m2. In all patients we investigated the following blood pressure parameters: average blood pressure (total, day-time and night-time, maximal blood pressure and dipping or non-dipping blood pressure pattern during night (for systolic and diastolic blood pressure, respectively. Results In body mass index beyond 30 kg/m2 only systolic blood pressure parameters were significantly higher - average blood pressure - during daytime (P=0.034 and during night (P=0.014; maximal blood pressure (P=0.001. In body mass index beyond 30 kg/m2, absence of normal blood pressure during night was significantly more often registered (P=0.007. Discussion and Conclusion The non-dipping blood pressure pattern and increase of systolic blood pressure only reveal hyper activation of sympathetic nervous system as a leading pathophysiological mechanism causing arterial hypertension in obese patients.

  12. Monitoring Blood Sugar: The Importance of Checking Blood Sugar Levels

    Science.gov (United States)

    ... Your 1- to 2-Year-Old Monitoring Blood Sugar KidsHealth > For Parents > Monitoring Blood Sugar Print A ... Tests Record Keeping The Importance of Checking Blood Sugar Levels Besides helping to keep blood sugar levels ( ...

  13. Monitoring Blood Sugar: The Importance of Checking Blood Sugar Levels

    Science.gov (United States)

    ... Feeding Your 1- to 2-Year-Old Monitoring Blood Sugar KidsHealth > For Parents > Monitoring Blood Sugar A ... Other Tests Record Keeping The Importance of Checking Blood Sugar Levels Besides helping to keep blood sugar ...

  14. Report on the Project for Establishment of the Standardized Korean Laboratory Terminology Database, 2015.

    Science.gov (United States)

    Jung, Bo Kyeung; Kim, Jeeyong; Cho, Chi Hyun; Kim, Ju Yeon; Nam, Myung Hyun; Shin, Bong Kyung; Rho, Eun Youn; Kim, Sollip; Sung, Heungsup; Kim, Shinyoung; Ki, Chang Seok; Park, Min Jung; Lee, Kap No; Yoon, Soo Young

    2017-04-01

    The National Health Information Standards Committee was established in 2004 in Korea. The practical subcommittee for laboratory test terminology was placed in charge of standardizing laboratory medicine terminology in Korean. We aimed to establish a standardized Korean laboratory terminology database, Korea-Logical Observation Identifier Names and Codes (K-LOINC) based on former products sponsored by this committee. The primary product was revised based on the opinions of specialists. Next, we mapped the electronic data interchange (EDI) codes that were revised in 2014, to the corresponding K-LOINC. We established a database of synonyms, including the laboratory codes of three reference laboratories and four tertiary hospitals in Korea. Furthermore, we supplemented the clinical microbiology section of K-LOINC using an alternative mapping strategy. We investigated other systems that utilize laboratory codes in order to investigate the compatibility of K-LOINC with statistical standards for a number of tests. A total of 48,990 laboratory codes were adopted (21,539 new and 16,330 revised). All of the LOINC synonyms were translated into Korean, and 39,347 Korean synonyms were added. Moreover, 21,773 synonyms were added from reference laboratories and tertiary hospitals. Alternative strategies were established for mapping within the microbiology domain. When we applied these to a smaller hospital, the mapping rate was successfully increased. Finally, we confirmed K-LOINC compatibility with other statistical standards, including a newly proposed EDI code system. This project successfully established an up-to-date standardized Korean laboratory terminology database, as well as an updated EDI mapping to facilitate the introduction of standard terminology into institutions.

  15. Sociological establishment of 'normative facts'

    Directory of Open Access Journals (Sweden)

    Vukićević Slobodan

    2002-01-01

    Full Text Available Every science is searching for 'it's facts', it's concept and categorical decree, and by this defines specific subject of it's science researching. Here, the researching is steered on identification of ontological contents of 'normative fact' in the aim of comprehension of it's categorical entity and conceptual disposition.'The normative fact' refers to importance, significance and sense which norm has, in other words, which is attributed to the norm by man and society, and which in the air of importance influence on it's behavior. Exclusive term of sociological science is 'normative fact' as behavior of an individual, groups, institutions and society with regard to establishment, application and changes of social norms.

  16. Dietary fiber and blood pressure control.

    Science.gov (United States)

    Aleixandre, A; Miguel, M

    2016-04-01

    In the past few years, new strategies to control blood pressure levels are emerging by developing new bioactive components of foods. Fiber has been linked to the prevention of a number of cardiovascular diseases and disorders. β-Glucan, the main soluble fiber component in oat grains, was initially linked to a reduction in plasma cholesterol. Several studies have shown afterward that dietary fiber may also improve glycaemia, insulin resistance and weight loss. The effect of dietary fiber on arterial blood pressure has been the subject of far fewer studies than its effect on the above-mentioned variables, but research has already shown that fiber intake can decrease arterial blood pressure in hypertensive rats. Moreover, certain fibers can improve arterial blood pressure when administered to hypertensive and pre-hypertensive subjects. The present review summarizes all those studies which attempt to establish the antihypertensive effects of dietary fiber, as well as its effect on other cardiovascular risk factors.

  17. A Single Counterexample Leads to Moral Belief Revision.

    Science.gov (United States)

    Horne, Zachary; Powell, Derek; Hummel, John

    2015-11-01

    What kind of evidence will lead people to revise their moral beliefs? Moral beliefs are often strongly held convictions, and existing research has shown that morality is rooted in emotion and socialization rather than deliberative reasoning. In addition, more general issues-such as confirmation bias-further impede coherent belief revision. Here, we explored a unique means for inducing belief revision. In two experiments, participants considered a moral dilemma in which an overwhelming majority of people judged that it was inappropriate to take action to maximize utility. Their judgments contradicted a utilitarian principle they otherwise strongly endorsed. Exposure to this scenario led participants to revise their belief in the utilitarian principle, and this revision persisted over several hours. This method provides a new avenue for inducing belief revision.

  18. The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure : meta-analysis of randomized trials

    NARCIS (Netherlands)

    Czernichow, Sebastien; Zanchetti, Alberto; Turnbull, Fiona; Barzi, Federica; Ninomiya, Toshiaru; Kengne, Andre-Pascal; Lambers Heerspink, Hiddo J.; Perkovic, Vlado; Huxley, Rachel; Arima, Hisatomi; Patel, Anushka; Chalmers, John; Woodward, Mark; MacMahon, Stephen; Neal, Bruce

    2011-01-01

    Background The benefits of reducing blood pressure are well established, but there remains uncertainty about whether the magnitude of the effect varies with the initial blood pressure level. The objective was to compare the risk reductions achieved by different blood pressure-lowering regimens among

  19. Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo

    NARCIS (Netherlands)

    Kortekaas, R; Leenders, KL; van Oostrom, JCH; Vaalburg, W; Bart, J; Willemsen, ATM; Hendrikse, NH

    2005-01-01

    Parkinson's disease (PD) is associated with a loss of neurons from the midbrain. The cause of PD is unknown, but it is established that certain neurotoxins can cause similar syndromes. The brain is normally protected from these noxious blood-borne chemicals by the blood-brain barrier which includes

  20. Chronic blood pressure control.

    Science.gov (United States)

    Brands, Michael W

    2012-10-01

    Chronic blood pressure is maintained within very narrow limits around an average value. However, the multitude of physiologic processes that participate in blood pressure control present a bewildering array of possibilities to explain how such tight control of arterial pressure is achieved. Guyton and Coleman and colleagues addressed this challenge by creating a mathematical model that integrated the short- and long-term control systems for overall regulation of the circulation. The hub is the renal-body fluid feedback control system, which links cardiac function and vascular resistance and capacitance with fluid volume homeostasis as the foundation for chronic blood pressure control. The cornerstone of that system is renal sodium excretory capability, which is defined by the direct effect of blood pressure on urinary sodium excretion, that is, "pressure natriuresis." Steady-state blood pressure is the pressure at which pressure natriuresis balances sodium intake over time; therefore, renal sodium excretory capability is the set point for chronic blood pressure. However, this often is misinterpreted as dismissing, or minimizing, the importance of nonrenal mechanisms in chronic blood pressure control. This article explains the renal basis for the blood pressure set point by focusing on the absolute dependence of our survival on the maintenance of sodium balance. Two principal threats to sodium balance are discussed: (1) a change in sodium intake or renal excretory capability and (2) a change in blood pressure. In both instances, circulatory homeostasis is maintained because the sodium balance blood pressure set point is reached.

  1. Belief Revision in the GOAL Agent Programming Language

    DEFF Research Database (Denmark)

    Spurkeland, Johannes Svante; Jensen, Andreas Schmidt; Villadsen, Jørgen

    2013-01-01

    Agents in a multiagent system may in many cases find themselves in situations where inconsistencies arise. In order to properly deal with these, a good belief revision procedure is required. This paper illustrates the usefulness of such a procedure: a certain belief revision algorithm is consider...... in order to deal with inconsistencies and, particularly, the issue of inconsistencies, and belief revision is examined in relation to the GOAL agent programming language....

  2. Creative revision - From rough draft to published paper

    Science.gov (United States)

    Buehler, M. F.

    1976-01-01

    The process of revising a technical or scientific paper can be performed more efficiently by the people involved (author, co-author, supervisor, editor) when the revision is controlled by breaking it into a series of steps. The revision process recommended here is based on the levels-of-edit concept that resulted from a study of the technical editorial function at the Jet Propulsion Laboratory of the California Institute of Technology. Types of revision discussed are Substantive, Policy, Language, Mechanical Style, Format, Integrity, and Copy Clarification.

  3. Is Peer Review Training Effective in Iranian EFL Students’ Revision?

    Directory of Open Access Journals (Sweden)

    Hadiseh Esmaeeli

    2014-08-01

    Full Text Available This study aims to investigate the effect of peer review training on the Iranian EFL students’ subsequent revision in an advanced writing class in Larestan Islamic Azad University. After 12 weeks class demonstration, teacher-reviewer conferences with 20 male and female students, the students’ first drafts, revisions, and reviewers’ comments were collected and compared the comments before and after peer review training. The findings revealed that the students incorporated significantly more comments into subsequent revisions after peer review training. Therefore, peer review training had a positive effect on the students’ subsequent revisions.

  4. My revision notes AQA GCSE computer science computing fundamentals

    CERN Document Server

    Cushing, Steve

    2013-01-01

    Unlock your full potential with this revision guide which focuses on the key content and skills you need to know. With My Revision Notes for AQA GCSE Computer Science, which perfectly matches the latest examined elements of the course, you can:. - Take control of your revision: plan and focus on the areas you need to revise, with advice, summaries and notes from author Steve Cushing. - Show you fully understand key topics by using specific strategies and theories to add depth to your knowledge of programming and computing issues and processes. - Apply programming and computing terms accurately

  5. 21 CFR 864.9100 - Empty container for the collection and processing of blood and blood components.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Empty container for the collection and processing of blood and blood components. 864.9100 Section 864.9100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Products Used In Establishments...

  6. Revision of Minimally Invasive Sacroiliac Joint Fixation: Technical Considerations and Case Studies Using Decortication and Threaded Implant Fixation

    Science.gov (United States)

    Fielding, Louis C

    2017-01-01

    Background Sacroiliac joint (SIJ) disease is increasingly recognized as a common source of low back pain. Arthrodesis of the SIJ has been shown to be clinically effective for this condition. In the last decade, minimally invasive (MI) SIJ fusion procedures have been developed to achieve the clinical effectiveness of open fusion procedures, with lower operative morbidity and faster recovery. However, SIJ fusion patients occasionally present with symptomatic nonunions necessitating revision. Methods Four patients who previously underwent MI SIJ arthrodesis returned with complaints of SIJ related pain confirmed by examination. Radiographic assessment showed lucency after fixation with triangular titanium interference implants. Loose implants were removed, and the patients were revised with a different MI SIJ fusion system that utilizes decortication, placement of autograft and graft extender, and fixation with cannulated threaded implants. The trajectory of the revision implants was in a more ventral-to-dorsal and caudal-to-cranial trajectory to place the implants perpendicularly through the articular portion of the SIJ. Results The triangular implants typically exhibited haloing lucency on radiographs and CT scans, and most were easily removed using the manufacturer’s instrumentation; only one implant was left in place as it was well-fixed. The removed implants exhibited little or no bony ongrowth. Decortication of the SIJ was performed, followed by placement of local autograft and fixation with 12.5 mm or 14.5mm diameter implants, as required. A more ventral-todorsal and caudal-to-cranial trajectory was established for the revision implants through the center of the articular region of the joint in order to maximize implant purchase in residual bone stock and achieve bony fusion through the articular portion of the SIJ. By six to twelve months post-revision, the presenting symptoms were successfully resolved in all patients. Conclusions Patients demonstrating

  7. Right patient, Right blood

    DEFF Research Database (Denmark)

    Selberg, Hanne; Madsen, Trine Stougaard

    2014-01-01

    Right patient, Right Blood Simulation based training in blood transfusion practice in nursing education Background: In spite of strict checking procedures to handling transfusion of blood severe adverse reactions are likely to happen and the major cause of morbidity occurs to be liable to human...... errors. Nursing students have limited possibility to practice safe blood transfusion during clinical placements. We introduced simulation-based workshops to reinforce safe transfusion practice and thus increase patient safety but equally important to bridge the gap between theory and practice. Objectives......: The objective of the current study was to test workshops focusing on procedures of safe blood transfusion by combining theory and practice, integrating current guidelines on safe blood transfusion and hereby help students to better recognize and handle errors and adverse reactions. Methods: 372 third year...

  8. Institute for Rock Magnetism established

    Science.gov (United States)

    Banerjee, Subir K.

    There is a new focal point for cooperative research in advanced rock magnetism. The University of Minnesota in Minneapolis has established an Institute for Rock Magnetism (IRM) that will provide free access to modern equipment and encourage visiting fellows to focus on important topics in rock magnetism and related interdisciplinary research. Funding for the first three years has been secured from the National Science Foundation, the W.M. Keck Foundation, and the University of Minnesota.In the fall of 1986, the Geomagnetism and Paleomagnetism (GP) section of the AGU held a workshop at Asilomar, Calif., to pinpoint important and emerging research areas in paleomagnetism and rock magnetism, and the means by which to achieve them. In a report of this workshop published by the AGU in September 1987, two urgent needs were set forth. The first was for interdisciplinary research involving rock magnetism, and mineralogy, petrology, sedimentology, and the like. The second need was to ease the access of rock magnetists and paleomagnetists around the country to the latest equipment in modern magnetics technology, such as magneto-optics or electronoptics. Three years after the publication of the report, we announced the opening of these facilities at the GP section of the AGU Fall 1990 Meeting. A classified advertisement inviting applications for visiting fellowships was published in the January 22, 1991, issue of Eos.

  9. Establishment of a reference interval for natural killer cell activity through flow cytometry and its clinical application in the diagnosis of hemophagocytic lymphohistiocytosis.

    Science.gov (United States)

    Chung, H J; Park, C J; Lim, J H; Jang, S; Chi, H S; Im, H J; Seo, J J

    2010-04-01

    Recently, the Histiocyte Society revised the diagnostic criteria for hemophagocytic lymphohistiocytosis (HLH) to include low or absent natural killer (NK) cell activity, according to local laboratory reference. The aim of this study was to establish reference interval for functional NK-cell activity in 63 healthy Korean individuals using a flow-cytometric assay. We used peripheral blood mononuclear cells (PBMCs) as effector cells and Fluorescein isothiocyanate-labeled K562 cells as target cells. NK-cell activity was calculated using the following equation: NK-cell activity (%) = (test lysis - spontaneous lysis) x 100/(maximum lysis - spontaneous lysis). NK-cell activity was analyzed in 13 known HLH patients and 16 suspected non-HLH patients using a flow-cytometric assay. The mean (+/-SD) cytotoxicity of PBMCs from healthy individuals was 20.9 +/- 5.3% and the reference interval was 11.8-31.9%. The mean NK-cell activity of HLH patients (8.3 +/- 8.9%) was significantly lower (P = 0.001) than that of non-HLH patients (20.1 +/- 7.8%). The sequential changes in NK-cell activity in the HLH group corresponded to clinical and laboratory findings following treatment. We successfully developed a functional NK-cell activity test for use in the clinical laboratory and obtained a reference interval of NK-cell activity from healthy donors. This assay, and associated reference interval, was used to analyze 30 clinically relevant specimens and the results were shown to be well correlated.

  10. Donating blood for research: a potential method for enhancing customer satisfaction of permanently deferred blood donors

    Science.gov (United States)

    Waller, Daniel; Thijsen, Amanda; Garradd, Allira; Hayman, Jane; Smith, Geoff

    2017-01-01

    Background Each year, a large number of individuals in Australia are deferred from donating blood. A deferral may have a negative impact on donor satisfaction and subsequent word-of-mouth communication. The Australian Red Cross Blood Service (the Blood Service) is, therefore, investigating options for managing service interactions with deferred donors to maintain positive relationships. While public research institutes in Australia have established independent research donor registries, other countries provide programmes allowing deferred donors to donate blood for research via blood collection agencies. This study examined attitudes towards donating blood for research use in a sample of permanently deferred Australian donors. Materials and methods Donors permanently deferred because of a risk of variant Creutzfeldt-Jakob disease (n=449) completed a postal survey that examined attitudes towards research donation. Results The majority of participants were interested in donating blood for research (96%), and joining a registry of research donors (93%). Participants preferred to donate for transfusion or clinical research, and were willing to travel large distances. Results indicated that positive attitudes towards the Blood Service would be extended if the opportunity to donate blood was provided. These findings indicate a desire for continued engagement with the Blood Service despite deferral. Discussion Donating blood for research is a potential way of maintaining positive relationships with permanently deferred donors which also benefits the health research community. Through maintaining positive relationships with deferred donors, positive word-of-mouth activity can be stimulated. Further work is needed to determine the feasibility of implementing research donation through the Blood Service in Australia. PMID:26674813

  11. Actitud Hacia las Matematicas: Revision Bibliografica (Attitudes Toward Mathematics: Revised Bibliography). Publication No. 39.

    Science.gov (United States)

    Rodriguez Feijoo, Nelida

    Investigations about attitudes toward mathematics carried out in the past decade were revised. The instruments used to measure attitudes toward mathematics were analysed as well as the attitudes toward different aspects of mathematics, their relation with other school subjects and their stability through time. Opinions about the influence of…

  12. Revising in two languages: A multidimensional comparison of online writing revisions in L1 en FL

    NARCIS (Netherlands)

    M. Stevenson; R. Schoonen; K. de Glopper

    2006-01-01

    It has frequently been claimed that, in foreign language writing, attention to linguistic processes inhibits attention available for higher level conceptual processing [e.g., Chenoweth & Hayes, 2001; Whalen & Ménard, 1995]. This study examines this hypothesis for foreign language revision processes

  13. The thesaurus review, renaissance, and revision

    CERN Document Server

    Roe, Sandra K

    2013-01-01

    Use this single source to uncover the origin and development of the thesaurus! The Thesaurus: Review, Renaissance, and Revision examines the historical development of the thesaurus and the standards employed for thesaurus construction. This book provides both the history of thesauri and tutorials on usage to increase your understanding of thesaurus creation, use, and evaluation. This reference tool offers essential information on thesauri in the digital environment, including Web sites, databases, and software. For 50 years, the thesaurus has been a core reference book; The Thesaurus: Review,

  14. Revision of the family Nothybidae (Diptera: Schizophora).

    Science.gov (United States)

    Lonsdale, O; Marshall, S A

    2016-04-05

    The family Nothybidae (Diptera: Schizophora) is revised. The family consists of 11 species in the single genus Nothybus Rondani, which occurs in Papua New Guinea, Nepal and much of the Oriental Region. Three species are described as new: N. absens spec. nov. (China), N. cataractus spec. nov. (Laos, Thailand) and N. procerus spec. nov. (India). Nothybus longithorax Rondani, 1875 is treated as a junior synonym of N. longicollis (Walker, 1856). Nothybus decorus Meijere, 1924 syn. nov. is included as a junior synonym of N. lineifer Enderlein, 1922.

  15. Revised numerical wrapper for PIES code

    Science.gov (United States)

    Raburn, Daniel; Reiman, Allan; Monticello, Donald

    2015-11-01

    A revised external numerical wrapper has been developed for the Princeton Iterative Equilibrium Solver (PIES code), which is capable of calculating 3D MHD equilibria with islands. The numerical wrapper has been demonstrated to greatly improve the rate of convergence in numerous cases corresponding to equilibria in the TFTR device where magnetic islands are present. The numerical wrapper makes use of a Jacobian-free Newton-Krylov solver along with adaptive preconditioning and a sophisticated subspace-restricted Levenberg-Marquardt backtracking algorithm. The details of the numerical wrapper and several sample results are presented.

  16. Technology status in support of refined technical baseline for the Spent Nuclear Fuel project. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Puigh, R.J.; Toffer, H.; Heard, F.J.; Irvin, J.J.; Cooper, T.D.

    1995-10-20

    The Spent Nuclear Fuel Project (SNFP) has undertaken technology acquisition activities focused on supporting the technical basis for the removal of the N Reactor fuel from the K Basins to an interim storage facility. The purpose of these technology acquisition activities has been to identify technology issues impacting design or safety approval, to establish the strategy for obtaining the necessary information through either existing project activities, or the assignment of new work. A set of specific path options has been identified for each major action proposed for placing the N Reactor fuel into a ``stabilized`` form for interim storage as part of this refined technical basis. This report summarizes the status of technology information acquisition as it relates to key decisions impacting the selection of specific path options. The following specific categories were chosen to characterize and partition the technology information status: hydride issues and ignition, corrosion, hydrogen generation, drying and conditioning, thermal performance, criticality and materials accountability, canister/fuel particulate behavior, and MCO integrity. This report represents a preliminary assessment of the technology information supporting the SNFP. As our understanding of the N Reactor fuel performance develops the technology information supporting the SNFP will be updated and documented in later revisions to this report. Revision 1 represents the incorporation of peer review comments into the original document. The substantive evolution in our understanding of the technical status for the SNFP (except section 3) since July 1995 have not been incorporated into this revision.

  17. [Review of the 2008 revision of the ethical guidelines for clinical studies].

    Science.gov (United States)

    Imoto, Masakatsu

    2010-05-01

    The ethical guidelines for clinical studies were revised in 2008 and enforced in April 2009. This was the second revision but first regular revision and largely reviewed. In particular, articles under the purview of the Institutional Review Board (IRB) for clinical studies are reviewed and enhanced. This additional role further increases the authority of the IRB, and those who fix the IRB must exhibit the activity of the IRB to the public and report to the MHLW annually. The provision of compensation for clinical studies on the evaluation of drugs and medical devices has been added to this version of the ethical guidelines. The compensation for interventional clinical studies using drugs and medical devices has not yet been decided, similar to "chiken," which is defined in pharmaceutical affairs laws (PAL). Since April 2009, some insurance offices have started offering special insurance covers for clinical studies. New registration rules have been established for clinical studies. Moreover, there is now a database for clinical study registration called "Japan Primary Registries Network (JPRN)," which is certified by WHO. This database comprises 3 open databases, which were originally independent, related to clinical trials in Japan. They are however under the purview of the National Institute of Public Health. This institution works in collaboration with the "International Clinical Trials Registry Platform (ICTRP)" of WHO.

  18. Transuranic waste characterization sampling and analysis methods manual. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Suermann, J.F.

    1996-04-01

    This Methods Manual provides a unified source of information on the sampling and analytical techniques that enable Department of Energy (DOE) facilities to comply with the requirements established in the current revision of the Transuranic Waste Characterization Quality Assurance Program Plan (QAPP) for the Waste Isolation Pilot Plant (WIPP) Transuranic (TRU) Waste Characterization Program (the Program) and the WIPP Waste Analysis Plan. This Methods Manual includes all of the testing, sampling, and analytical methodologies accepted by DOE for use in implementing the Program requirements specified in the QAPP and the WIPP Waste Analysis Plan. The procedures in this Methods Manual are comprehensive and detailed and are designed to provide the necessary guidance for the preparation of site-specific procedures. With some analytical methods, such as Gas Chromatography/Mass Spectrometry, the Methods Manual procedures may be used directly. With other methods, such as nondestructive characterization, the Methods Manual provides guidance rather than a step-by-step procedure. Sites must meet all of the specified quality control requirements of the applicable procedure. Each DOE site must document the details of the procedures it will use and demonstrate the efficacy of such procedures to the Manager, National TRU Program Waste Characterization, during Waste Characterization and Certification audits.

  19. Project specific quality assurance plan, W-151, Tank 241-AZ-101 waste retrieval system. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Manthei, M.E.

    1994-11-21

    This project specific quality assurance program plan establishes the responsibility for the implementation of QA requirements, defines and documents the QA requirements associated with design, procurement, and construction, and defines and documents the degree of QA reviews and verifications on the design and construction necessary to assure compliance to project and DOE requirements. Revision 2 updates the QAPP to provide concurrence with approved work scope deletion. In addition, the Quality Assurance Program Index is being updated to reflect the current Quality Assurance Program requirements per DOE Order 5700.6C.

  20. Revisions to the JDL data fusion model

    Science.gov (United States)

    Steinberg, Alan N.; Bowman, Christopher L.; White, Franklin E.

    1999-03-01

    The Data Fusion Model maintained by the Joint Directors of Laboratories (JDL) Data Fusion Group is the most widely-used method for categorizing data fusion-related functions. This paper discusses the current effort to revise the expand this model to facilitate the cost-effective development, acquisition, integration and operation of multi- sensor/multi-source systems. Data fusion involves combining information - in the broadest sense - to estimate or predict the state of some aspect of the universe. These may be represented in terms of attributive and relational states. If the job is to estimate the state of a people, it can be useful to include consideration of informational and perceptual states in addition to the physical state. Developing cost-effective multi-source information systems requires a method for specifying data fusion processing and control functions, interfaces, and associate databases. The lack of common engineering standards for data fusion systems has been a major impediment to integration and re-use of available technology: current developments do not lend themselves to objective evaluation, comparison or re-use. This paper reports on proposed revisions and expansions of the JDL Data FUsion model to remedy some of these deficiencies. This involves broadening the functional model and related taxonomy beyond the original military focus, and integrating the Data Fusion Tree Architecture model for system description, design and development.

  1. [Revision of the drinking water regulations].

    Science.gov (United States)

    Hauswirth, S

    2011-11-01

    The revision the Drinking Water Regulations will come into effect on 01.11.2011. Surveillance authorities and owners of drinking water supply systems had hoped for simplifications and reductions because of the new arrangements. According to the official statement for the revision the legislature intended to create more clarity, consider new scientific findings, to change regulations that have not been proved to close regulatory gaps, to deregulate and to increase the high quality standards. A detailed examination of the regulation text, however, raises doubts. The new classification of water supply systems requires different modalities of registration, water analyses and official observation, which will complicate the work of the authorities. In particular, the implementation of requirements of registration and examination for the owners of commercial and publicly-operated large hot-water systems in accordance with DVGW Worksheet W 551 requires more effort. According to the estimated 30 000 cases of legionellosis in Germany the need for a check of such systems for Legionella, however, is not called into question. Furthermore, the development of sampling plans and the monitoring of mobile water supply systems requires more work for the health authorities.

  2. A Way to Revised Quantum Electrodynamics

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2012-04-01

    Full Text Available In conventional theoretical physics and its Standard Model the guiding principle is that the equations are symmetrical. This limitation leads to a number of difficulties, because it does not permit masses for leptons and quarks, the electron tends to “explode” un- der the action of its self-charge, a corresponding photon model has no spin, and such a model cannot account for the “needle radiation” proposed by Einstein and observed in the photoelectric e ff ect and in two-slit experiments. This paper summarizes a revised Lorentz and gauge invariant quantum electrodynamic theory based on a nonzero electric field divergence in the vacuum and characterized by linear intrinsic broken symmetry. It thus provides an alternative to the Higgs concept of nonlinear spontaneous broken sym- metry, for solving the difficulties of the Standard Model. New results are obtained, such as nonzero and finite lepton rest masses, a point-charge-like behavior of the electron due to a revised renormalization procedure, a magnetic volume force which counteracts the electrostatic eigen-force of the electron, a nonzero spin of the photon and of light beams, needle radiation, and an improved understanding of the photoelectric effect, two-slit ex- periments, electron-positron pair formation, and cork-screw-shaped light beams.

  3. The JFK Coma Recovery Scale--Revised.

    Science.gov (United States)

    Kalmar, Kathleen; Giacino, Joseph T

    2005-01-01

    The JFK Coma Recovery Scale (CRS) was developed to help characterise and monitor patients functioning at Rancho Levels I-IV and has been used widely in both clinical and research settings within the US and Europe. The CRS was recently revised to address a number of concerns emanating from our own clinical experience with the scale, feedback from users and researchers as well as the results of Rasch analyses. Additionally, the CRS did not include all of the behavioural criteria necessary to diagnose the minimally conscious state (MCS), thereby limiting diagnostic utility. The revised JFK Coma Recovery Scale (CRS-R) includes addition of new items, merging of items found to be statistically similar, deletion or modification of items showing poor fit with the scale's underlying construct, renaming of items, more stringent scoring criteria, and quantification of elicited behaviours to improve accuracy of rating. Psychometric properties of the CRS-R appear to meet standards for measurement and evaluation tools for use in clinical and research settings, and diagnostic application suggests that the scale is capable of discriminating patients in the minimally conscious state from those in the vegetative state.

  4. Curriculum revision: product innovation for quality outcomes.

    Science.gov (United States)

    Thomas, Georgianna; Carroll, V Susan

    2006-01-01

    The education of any professional discipline rests on a curricular foundation that reflects the discipline's theory and knowledge bases, practice patterns, and unique skills. In addition, professional health care education must respond to and reflect changes in technology, societal definitions of health and wellness, and broad social issues such as access to care, health care funding, and changing patient demographics. These issues are interwoven with efforts to also provide high-quality education with positive learning outcomes. In this article, the authors describe a school of nursing's efforts to revise its curriculum to reflect a professional shift in focus to community-based nursing practice and the goals of the federal health goals outlined in Healthy People 2010. The revision also served as the starting point for a change in the process through which the college will seek accreditation in the future; this process-Academic Quality Improvement Program-requires institutions of higher learning to use a continuous quality model as its base.

  5. Three Principles to REVISE People's Unethical Behavior.

    Science.gov (United States)

    Ayal, Shahar; Gino, Francesca; Barkan, Rachel; Ariely, Dan

    2015-11-01

    Dishonesty and unethical behavior are widespread in the public and private sectors and cause immense annual losses. For instance, estimates of U.S. annual losses indicate $1 trillion paid in bribes, $270 billion lost due to unreported income, and $42 billion lost in retail due to shoplifting and employee theft. In this article, we draw on insights from the growing fields of moral psychology and behavioral ethics to present a three-principle framework we call REVISE. This framework classifies forces that affect dishonesty into three main categories and then redirects those forces to encourage moral behavior. The first principle, reminding, emphasizes the effectiveness of subtle cues that increase the salience of morality and decrease people's ability to justify dishonesty. The second principle, visibility, aims to restrict anonymity, prompt peer monitoring, and elicit responsible norms. The third principle, self-engagement, increases people's motivation to maintain a positive self-perception as a moral person and helps bridge the gap between moral values and actual behavior. The REVISE framework can guide the design of policy interventions to defeat dishonesty.

  6. The structure of post-traumatic stress symptoms in survivors of war: confirmatory factor analyses of the Impact of Event Scale—Revised

    NARCIS (Netherlands)

    N. Morina; H.F. Böhme; D. Ajdukovic; M. Bogic; T. Franciskovic; G.M. Galeazzi; A. Kucukalic; D. Lecic-Tosevski; M. Popovski; M. Schützwohl; U. Stangier; S. Priebe

    2010-01-01

    The study aimed at establishing the factor structure of the Impact of Event Scale—Revised (IES-R) in survivors of war. A total sample of 4167 participants with potentially traumatic experiences during the war in Ex-Yugoslavia was split into three samples: two independent samples of people who stayed

  7. Blood Clotting and Pregnancy

    Medline Plus

    Full Text Available ... just had a baby, you are at greater risk of developing a blood clot. Blood clots in pregnant women tend to form in the deep veins of the legs or in the pelvic area. This condition is known as deep vein thrombosis (DVT). Pulmonary embolism (PE) is a life-threatening ...

  8. Virtual blood bank.

    Science.gov (United States)

    Wong, Kit Fai

    2011-01-24

    Virtual blood bank is the computer-controlled, electronically linked information management system that allows online ordering and real-time, remote delivery of blood for transfusion. It connects the site of testing to the point of care at a remote site in a real-time fashion with networked computers thus maintaining the integrity of immunohematology test results. It has taken the advantages of information and communication technologies to ensure the accuracy of patient, specimen and blood component identification and to enhance personnel traceability and system security. The built-in logics and process constraints in the design of the virtual blood bank can guide the selection of appropriate blood and minimize transfusion risk. The quality of blood inventory is ascertained and monitored, and an audit trail for critical procedures in the transfusion process is provided by the paperless system. Thus, the virtual blood bank can help ensure that the right patient receives the right amount of the right blood component at the right time.

  9. Blood Test: Bilirubin

    Science.gov (United States)

    ... Your 1- to 2-Year-Old Blood Test: Bilirubin KidsHealth > For Parents > Blood Test: Bilirubin A A A What's in this article? What ... Análisis de sangre: bilirrubina What It Is A bilirubin test measures the level of bilirubin (a byproduct ...

  10. Virtual blood bank

    Directory of Open Access Journals (Sweden)

    Kit Fai Wong

    2011-01-01

    Full Text Available Virtual blood bank is the computer-controlled, electronically linked information management system that allows online ordering and real-time, remote delivery of blood for transfusion. It connects the site of testing to the point of care at a remote site in a real-time fashion with networked computers thus maintaining the integrity of immunohematology test results. It has taken the advantages of information and communication technologies to ensure the accuracy of patient, specimen and blood component identification and to enhance personnel traceability and system security. The built-in logics and process constraints in the design of the virtual blood bank can guide the selection of appropriate blood and minimize transfusion risk. The quality of blood inventory is ascertained and monitored, and an audit trail for critical procedures in the transfusion process is provided by the paperless system. Thus, the virtual blood bank can help ensure that the right patient receives the right amount of the right blood component at the right time.

  11. Give blood at CERN

    CERN Multimedia

    SC Unit

    2008-01-01

    ACCIDENTS and ILLNESSES don’t take a break! DO SOMETHING AMAZING - GIVE BLOOD! IT’S IN ALL OUR INTERESTS. 30 July 2008 from 9.30 a.m. to 4 p.m. CERN RESTAURANT NOVAE First floor - Salle des Pas Perdus After you have given blood, you are invited to partake of refreshments kindly offered by NOVAE.

  12. How Blood Clots

    Science.gov (United States)

    ... Japanese Espaniol Find information on medical topics, symptoms, drugs, procedures, news and more, written in everyday language. * This is ... Process How Blood Clots Resources In This Article Drugs Mentioned In This Article ... of the Blood (News) Is Binge-Watching Hazardous to Your Health? (News) ...

  13. [Blood Count Specimen].

    Science.gov (United States)

    Tamura, Takako

    2015-12-01

    The circulating blood volume accounts for 8% of the body weight, of which 45% comprises cellular components (blood cells) and 55% liquid components. We can measure the number and morphological features of blood cells (leukocytes, red blood cells, platelets), or count the amount of hemoglobin in a complete blood count: (CBC). Blood counts are often used to detect inflammatory diseases such as infection, anemia, a bleeding tendency, and abnormal cell screening of blood disease. This count is widely used as a basic data item of health examination. In recent years, clinical tests before consultation have become common among outpatient clinics, and the influence of laboratory values on consultation has grown. CBC, which is intended to count the number of raw cells and to check morphological features, is easily influenced by the environment, techniques, etc., during specimen collection procedures and transportation. Therefore, special attention is necessary to read laboratory data. Providing correct test values that accurately reflect a patient's condition from the laboratory to clinical side is crucial. Inappropriate medical treatment caused by erroneous values resulting from altered specimens should be avoided. In order to provide correct test values, the daily management of devices is a matter of course, and comprehending data variables and positively providing information to the clinical side are important. In this chapter, concerning sampling collection, blood collection tubes, dealing with specimens, transportation, and storage, I will discuss their effects on CBC, along with management or handling methods.

  14. Blood Gases Test

    Science.gov (United States)

    ... prevent any bleeding from the site. Sometimes mixed venous blood taken from a central line is used in particular situations, such as in cardiac catheterization labs and by transplant services. Careful interpretation of the results is required. Peripheral venous blood, such as that taken from a vein ...

  15. BLOOD DONORS CAMPAIGN

    CERN Multimedia

    2001-01-01

    A blood donors campaign, organized by the Centre de Transfusion Sanguine of Geneva will be held at CERN on Tuesday 13 March 2001 in restaurant nr 2, from 9.00 to 16.30 hrs If you already have a card giving your blood group, please bring this with you.

  16. BLOOD DONORS CAMPAIGN

    CERN Multimedia

    2001-01-01

    A blood donors campaign, organized by the Centre de Transfusion d'Annemasse will be held at CERN on Tuesday 14 November 2001 in restaurant nr 2, from 9.00 to 16.30 hrs If you already have a card giving your blood group, please bring this with you.

  17. BLOOD DONORS CAMPAIGN

    CERN Multimedia

    Medical Service

    2002-01-01

    Tuesday 19 March 2002 in restaurant nr 2, from 9.00 to 16.30 hrs A blood donors campaign, organized by the Centre de Transfusion sanguine of Geneva If you already have a card giving your blood group, please bring this with you.

  18. BLOOD DONORS CAMPAIGN

    CERN Document Server

    2000-01-01

    A blood donors campaign, organized by the Établissement de Transfusion de Rhône-Alpes will be held at CERN on Tuesday 14 November 2000 in restaurant nr 2, from 8.30 to 16.30 hrs If you already have a card giving your blood group, please bring this with you.

  19. BLOOD DONORS CAMPAIGN

    CERN Document Server

    2002-01-01

    Wednesday 13 November 2002 in restaurant nr 2, from 8.30 to 16.30 hrs will be held a blood donors campaign, organized by the Etablissement de Transfusion de Haute-Savoie If you already have a card giving your blood group, please bring this with you.

  20. Blood Type Game

    Science.gov (United States)

    ... Time Donors The Fear of Needles LGBTQ+ Donors Blood Donor Community Real Stories SleevesUp Games Facebook Avatars and Badges Banners eCards Enter your zip code to find: Regional Promotions Local News Blood Drives & More! Or find the Red Cross chapter ...

  1. Preventing High Blood Pressure

    Science.gov (United States)

    ... Web Sites Division for Heart Disease and Stroke Prevention Stroke Heart Disease Cholesterol Salt Million Hearts® WISEWOMAN Preventing High Blood Pressure: Healthy Living Habits Recommend on Facebook Tweet Share Compartir By living a healthy lifestyle, you can help keep your blood pressure in ...

  2. Revision of Begomovirus taxonomy based on pairwise sequence comparisons

    KAUST Repository

    Brown, Judith K.

    2015-04-18

    Viruses of the genus Begomovirus (family Geminiviridae) are emergent pathogens of crops throughout the tropical and subtropical regions of the world. By virtue of having a small DNA genome that is easily cloned, and due to the recent innovations in cloning and low-cost sequencing, there has been a dramatic increase in the number of available begomovirus genome sequences. Even so, most of the available sequences have been obtained from cultivated plants and are likely a small and phylogenetically unrepresentative sample of begomovirus diversity, a factor constraining taxonomic decisions such as the establishment of operationally useful species demarcation criteria. In addition, problems in assigning new viruses to established species have highlighted shortcomings in the previously recommended mechanism of species demarcation. Based on the analysis of 3,123 full-length begomovirus genome (or DNA-A component) sequences available in public databases as of December 2012, a set of revised guidelines for the classification and nomenclature of begomoviruses are proposed. The guidelines primarily consider a) genus-level biological characteristics and b) results obtained using a standardized classification tool, Sequence Demarcation Tool, which performs pairwise sequence alignments and identity calculations. These guidelines are consistent with the recently published recommendations for the genera Mastrevirus and Curtovirus of the family Geminiviridae. Genome-wide pairwise identities of 91 % and 94 % are proposed as the demarcation threshold for begomoviruses belonging to different species and strains, respectively. Procedures and guidelines are outlined for resolving conflicts that may arise when assigning species and strains to categories wherever the pairwise identity falls on or very near the demarcation threshold value.

  3. Text Revision in Deaf and Hearing Bilingual Students

    Science.gov (United States)

    Teruggi, Lilia A.; Gutiérrez-Cáceres, Rafaela

    2016-01-01

    In this study we explored the revision process and strategies implemented by deaf and hearing students who attend the same bilingual school context (LIS and Italian). For that we analysed and compared the types and quality of revisions made by deaf and hearing participants to their first draft of a narrative text ("Frog, Where Are You?")…

  4. Inferential revision in narrative texts: An ERP study.

    Science.gov (United States)

    Pérez, Ana; Cain, Kate; Castellanos, María C; Bajo, Teresa

    2015-11-01

    We evaluated the process of inferential revision during text comprehension in adults. Participants with high or low working memory read short texts, in which the introduction supported two plausible concepts (e.g., 'guitar/violin'), although one was more probable ('guitar'). There were three possible continuations: a neutral sentence, which did not refer back to either concept; a no-revise sentence, which referred to a general property consistent with either concept (e.g., '…beautiful curved body'); and a revise sentence, which referred to a property that was consistent with only the less likely concept (e.g., '…matching bow'). Readers took longer to read the sentence in the revise condition, indicating that they were able to evaluate their comprehension and detect a mismatch. In a final sentence, a target noun referred to the alternative concept supported in the revise condition (e.g., 'violin'). ERPs indicated that both working memory groups were able to evaluate their comprehension of the text (P3a), but only high working memory readers were able to revise their initial incorrect interpretation (P3b) and integrate the new information (N400) when reading the revise sentence. Low working memory readers had difficulties inhibiting the no-longer-relevant interpretation and thus failed to revise their situation model, and they experienced problems integrating semantically related information into an accurate memory representation.

  5. China Revises Its Oil Resources Rules for Foreign Cooperation

    Institute of Scientific and Technical Information of China (English)

    Sun Xiujuan

    2001-01-01

    @@ The State Council has recently revised two regulations concerning recovery of oil and gas resources to relax the restrictions on foreign companies.The revised regulations are "The Rules of the People's Republic of China for Cooperative Recovery of Onshore Petroleum Resources" and "The Rules of the People's Republic of China for Cooperative Recovery of Offshore Petroleum Resources".

  6. 75 FR 17253 - Revisions to the General Conformity Regulations

    Science.gov (United States)

    2010-04-05

    ... Protection Agency 40 CFR Parts 51 and 93 Revisions to the General Conformity Regulations; Final Rule #0;#0... PROTECTION AGENCY 40 CFR Parts 51 and 93 RIN 2060-AH93 Revisions to the General Conformity Regulations AGENCY... or Federal implementation plan (SIP, TIP, or FIP) for attaining clean air (``General...

  7. Revision of Alyxia (Apocynaceae). Part 2: Pacific Islands and Australia

    NARCIS (Netherlands)

    Middleton, David J.

    2002-01-01

    The genus Alyxia is revised for Australia and the islands of the Pacific Ocean as the second and final part of a complete revision of the genus. 39 species are recognised for this area of which three are new to science, two are new combinations and one is a new name. 14 species are found in Australi

  8. Revised SWAT. The integrated burnup calculation code system

    Energy Technology Data Exchange (ETDEWEB)

    Suyama, Kenya; Mochizuki, Hiroki [Department of Fuel Cycle Safety Research, Nuclear Safety Research Center, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan); Kiyosumi, Takehide [The Japan Research Institute, Ltd., Tokyo (Japan)

    2000-07-01

    SWAT is an integrated burnup code system developed for analysis of post irradiation examination, transmutation of radioactive waste, and burnup credit problem. This report shows an outline and a user's manual of revised SWAT. This revised SWAT includes expansion of functions, increasing supported machines, and correction of several bugs reported from users of previous SWAT. (author)

  9. Evaluation and Revision of an Introduction to Experiential Rotations Course

    Science.gov (United States)

    Dy, Eliza A.; Nisly, Sarah A.

    2014-01-01

    The objectives of this study were to evaluate the perceived student value of topics taught in Butler University's Introduction to Experiential Rotations (RX500) course, implement course revisions to address any perceived weaknesses, and to reassess the course following implementation of those course revisions. Advanced Pharmacy Practice Experience…

  10. Proposal for revision of ISO 4377: Flat-V weirs

    NARCIS (Netherlands)

    Kalkwijk, J.P.T.; Lianxiang, W.

    1983-01-01

    In ISO/TC 113/SC 2/308 it was suggested that ISO 4377 could be significantly simplified as far as the calculation of discharge was involved. The proposal for revision is based upon this suggestion. The revision is fully based upon the material given in ISO 4377. In that respect no changes have been

  11. 75 FR 57956 - Draft Revision of the Federalwide Assurance

    Science.gov (United States)

    2010-09-23

    ... HUMAN SERVICES Draft Revision of the Federalwide Assurance AGENCY: Department of Health and Human... Assistant Secretary for Health, is announcing the availability of the draft revised Federalwide Assurance (FWA) form and Terms of Assurance, and is seeking comment on these draft documents. OHRP is...

  12. Promoting Revision through Blogging in a Second Grade Classroom

    Science.gov (United States)

    Young, Chase; Stover, Katie

    2015-01-01

    This study helped the researchers to determine if blogging as a revision strategy in a second grade classroom was beneficial. Nineteen second grade students wrote expository essays and made revisions and edits based on peer feedback in a blogging environment. Six elementary school teachers independently rated the students' writing samples using…

  13. Revisions of endoprosthetic reconstructions after limb salvage in musculoskeletal oncology

    NARCIS (Netherlands)

    Renard, AJS; Veth, RPH; Schreuder, HWB; van Horn, J; Keller, A; Schraffordt Koops, H.

    1998-01-01

    Of 91 limb-salvage procedures using prosthetic reconstructions because of primary or metastatic bone and soft-tissue tumors 26 revisions were performed in 16 patients. Revision was due to polyethylene wear (9 cases), aseptic loosening (8 cases), recurrent hip dislocation (3 cases), prosthetic stem f

  14. 75 FR 71632 - Revised Medical Criteria for Evaluating Mental Disorders

    Science.gov (United States)

    2010-11-24

    ... ADMINISTRATION 20 CFR Parts 404 and 416 RIN 0960-AF69 Revised Medical Criteria for Evaluating Mental Disorders... mental disorders that we receive during this reopened comment period. DATES: To ensure that your comments..., 2010 the comment period on one aspect of our proposed rules to revise our mental disorders...

  15. The New & Revised Consumer Price Indexes. ERS Information Aid.

    Science.gov (United States)

    Kowalski, Joan P. Sullivan; Porwoll, Paul J.

    The purpose of this Information Aid is to alert school officials to changes and revisions in the Consumer Price Index (CPI), to familiarize them with differences between the former CPI and the new and revised indexes, to demonstrate how the U.S. Bureau of Labor Statistics (BLS) computes changes in the CPI, to indicate appropriate uses of the CPI,…

  16. Initiating Curriculum Revision: Exploring the Practices of Educational Developers

    Science.gov (United States)

    O'Neill, Geraldine

    2010-01-01

    Curriculum revision is an important part of academic work. Despite theoretical literature on curriculum development and design, there is a scarcity of literature available for either academic staff or novice educational developers on the initiation of this curriculum revision process. This study, therefore, set out to explore the practices of…

  17. 75 FR 62459 - Revision of Class E Airspace; Unalakleet, AK

    Science.gov (United States)

    2010-10-12

    ... for air traffic management of Instrument Flight Rules (IFR) operations. DATES: Effective 0901 UTC... Federal Register to revise Class E airspace at Unalakleet, AK (75 FR 32865). Interested parties were... amendments to existing SIAPs require that the orientation and dimensions of Class E airspace be revised...

  18. A revision of the Pliocene and Quaternary Lutrinae from Europe

    NARCIS (Netherlands)

    Willemsen, G.F.

    1992-01-01

    In this paper, a revision of the Pliocene and Quaternary Lutrinae from Europe is presented. Such a revision, including fossil material, has not been published since the work of Pohle (1919). Three tribes within the Lutrinae are recognized: the Lutrini, the Aonyxini and the Enhydrini. The latter comp

  19. Blog-Based Peer Response for L2 Writing Revision

    Science.gov (United States)

    Pham, Vu Phi Ho; Usaha, Siriluck

    2016-01-01

    Few studies have been conducted to see how blog-based peer response helps students to improve their writing revisions. The present study investigates peer comments made through blogs, the nature of the comments and their areas of focus, and the ratios of students incorporating suggestions made through blog-based comments into revisions of their…

  20. 78 FR 19416 - Revisions to Patent Term Adjustment

    Science.gov (United States)

    2013-04-01

    ... United States Patent and Trademark Office 37 CFR Part 1 RIN 0651-AC84 Revisions to Patent Term Adjustment AGENCY: United States Patent and Trademark Office, Commerce. ACTION: Interim final rule. SUMMARY: The United States Patent and Trademark Office (Office) is revising the rules of practice to implement...

  1. Using a Local Area Network to Teach Computer Revision Skills.

    Science.gov (United States)

    Thompson, Diane P.

    1989-01-01

    Describes the use of a local area network and video switching equipment in teaching revision skills on computer. Explains that reading stories from texts, rewriting them from differing character viewpoints, and editing them as a group exposed students to a variety of writing problems and stimulated various revision strategies. (SG)

  2. Modeling data revisions : Measurement error and dynamics of "true" values

    NARCIS (Netherlands)

    Jacobs, Jan P. A. M.; van Norden, Simon

    2011-01-01

    Policy makers must base their decisions on preliminary and partially revised data of varying reliability. Realistic modeling of data revisions is required to guide decision makers in their assessment of current and future conditions. This paper provides a new framework with which to model data revis

  3. The Effects of Online Feedback Training on Students' Text Revision

    Science.gov (United States)

    Yang, Yu-Fen; Meng, Wen-Ting

    2013-01-01

    Oftentimes, college students who learn English as a Foreign Language (EFL) provide their peers with incorrect and misleading feedback during text revision. To improve the effectiveness of peer feedback, this study examined the degree to which online feedback training impacted EFL college students' text revisions. A sample of 50 college students…

  4. 77 FR 13969 - Revising Standards Referenced in the Acetylene Standard

    Science.gov (United States)

    2012-03-08

    ... the Acetylene Standard AGENCY: Occupational Safety and Health Administration (OSHA), Department of... date of its direct final rule that revises the Acetylene Standard for general industry by updating the... that revised the Acetylene Standard for general industry by updating a reference to the Compressed...

  5. 76 FR 75840 - Revising Standards Referenced in the Acetylene Standard

    Science.gov (United States)

    2011-12-05

    ... the Acetylene Standard AGENCY: Occupational Safety and Health Administration (OSHA), Department of... rulemaking, the Agency is proposing to revise its Acetylene Standard for general industry by updating a... Companion Proposed Rule C. Request for Comment III. Summary and Explanation of Revisions to the...

  6. The reliability of the Structured Interview for Schizotypy-Revised

    NARCIS (Netherlands)

    Vollema, MG; Ormel, J

    2000-01-01

    We investigated the reliability of the Structured Interview for Schizotypy-Revised (SIS-R). The original interview (SIS) was developed by Kendler, We revised the SIS, primarily by standardizing the rating procedures. Operational definitions and explicit criteria for rating were given. We introduced

  7. Is Peer Review Training Effective in Iranian EFL Students' Revision?

    Science.gov (United States)

    Esmaeeli, Hadiseh; Abasi, Maasumeh; Soori, Afshin

    2014-01-01

    This study aims to investigate the effect of peer review training on the Iranian EFL students' subsequent revision in an advanced writing class in Larestan Islamic Azad University. After 12 weeks class demonstration, teacher-reviewer conferences with 20 male and female students, the students' first drafts, revisions, and reviewers' comments were…

  8. Merlin C. Wittrock and the Revision of Bloom's Taxonomy

    Science.gov (United States)

    Krathwohl, David R.; Anderson, Lorin W.

    2010-01-01

    Merl Wittrock, a cognitive psychologist who had proposed a generative model of learning, was an essential member of the group that over a period of 5 years revised the "Taxonomy of Educational Objectives," originally published in 1956. This article describes the development of that 2001 revision (Anderson and Krathwohl, Editors) and Merl's…

  9. Blood-type distribution

    Science.gov (United States)

    Kim, Beom Jun; Myeong Lee, Dong; Hun Lee, Sung; Gim, Wan-Suk

    2007-01-01

    We statistically verify the Hardy-Weinberg principle in genetics by investigating the independence of ABO-blood types of married couples. The allelic frequencies derived from the phenotypic frequencies in ethnic groups via the Hardy-Weinberg principle are used to define a genetic distance (called the blood distance in this work) between two groups. The blood distances are compared with the geographic distances, and then used to construct a network of ethnic groups. We also investigate the relationship between the ABO blood types and the human personalities, gauged by the Myers-Briggs-type indicator (MBTI) psychological test. The statistical χ2-test reveals the independence between the blood types and MBTI results with an exception of type B males. A psychological implication is discussed.

  10. A VARIATIONAL MODEL FOR 2-D MICROPOLAR BLOOD FLOW

    Institute of Scientific and Technical Information of China (English)

    He Ji-huan

    2003-01-01

    The micropolar fluid model is an essential generalization of the well-established Navier-Stokes model in the sense that it takes into account the microstructure of the fluid.This paper is devolted to establishing a variational principle for 2-D incompressible micropolar blood flow.

  11. Legal and ethical issues in safe blood transfusion

    Directory of Open Access Journals (Sweden)

    Shivaram Chandrashekar

    2014-01-01

    Full Text Available Legal issues play a vital role in providing a framework for the Indian blood transfusion service (BTS, while ethical issues pave the way for quality. Despite licensing of all blood banks, failure to revamp the Drugs and Cosmetic Act (D and C Act is impeding quality. Newer techniques like chemiluminescence or nucleic acid testing (NAT find no mention in the D and C Act. Specialised products like pooled platelet concentrates or modified whole blood, therapeutic procedures like erythropheresis, plasma exchange, stem cell collection and processing technologies like leukoreduction and irradiation are not a part of the D and C Act. A highly fragmented BTS comprising of over 2500 blood banks, coupled with a slow and tedious process of dual licensing (state and centre is a hindrance to smooth functioning of blood banks. Small size of blood banks compromises blood safety. New blood banks are opened in India by hospitals to meet requirements of insurance providers or by medical colleges as this a Medical Council of India (MCI requirement. Hospital based blood banks opt for replacement donation as they are barred by law from holding camps. Demand for fresh blood, lack of components, and lack of guidelines for safe transfusion leads to continued abuse of blood. Differential pricing of blood components is difficult to explain scientifically or ethically. Accreditation of blood banks along with establishment of regional testing centres could pave the way to blood safety. National Aids Control Organisation (NACO and National Blood Transfusion Council (NBTC deserve a more proactive role in the licensing process. The Food and Drug Administration (FDA needs to clarify that procedures or tests meant for enhancement of blood safety are not illegal.

  12. Predictors of Revision Surgery After Primary Anterior Cruciate Ligament Reconstruction

    Science.gov (United States)

    Yabroudi, Mohammad A.; Björnsson, Haukur; Lynch, Andrew D.; Muller, Bart; Samuelsson, Kristian; Tarabichi, Majd; Karlsson, Jón; Fu, Freddie H.; Harner, Christopher D.; Irrgang, James J.

    2016-01-01

    Background: Revision anterior cruciate ligament (ACL) reconstruction surgery occurs in 5% to 15% of individuals undergoing ACL reconstruction. Identifying predictors for revision ACL surgery is of essence in the pursuit of creating adequate prevention programs and to identify individuals at risk for reinjury and revision. Purpose: To determine predictors of revision ACL surgery after failed primary ACL reconstruction. Study Design: Case-control study; Level of evidence, 3. Methods: A total of 251 participants (mean age ± SD, 26.1 ± 9.9 years) who had undergone primary ACL reconstruction 1 to 5 years earlier completed a comprehensive survey to determine predictors of revision ACL surgery at a mean 3.4 ± 1.3 years after the primary ACL reconstruction. Potential predictors that were assessed included subject characteristics (age at the time of surgery, time from injury to surgery, sex, body mass index, preinjury activity level, return to sport status), details of the initial injury (mechanism; concomitant injury to other ligaments, menisci, and cartilage), surgical details of the primary reconstruction (Lachman and pivot shift tests under anesthesia, graft type, femoral drilling technique, reconstruction technique), and postoperative course (length of rehabilitation, complications). Univariate and multivariate logistic regression analyses were performed to identify factors that predicted the need for revision ACL surgery. Results: Overall, 21 (8.4%) subjects underwent revision ACL surgery. Univariate analysis showed that younger age at the time of surgery (P = .003), participation in sports at a competitive level (P = .023), and double-bundle ACL reconstruction (P = .024) predicted increased risk of revision ACL surgery. Allograft reconstructions also demonstrated a trend toward greater risk of revision ACL surgery (P = .076). No other variables were significantly associated with revision ACL surgery. Multivariate analysis revealed that revision ACL surgery was

  13. Fostering revision of argumentative writing through structured peer assessment.

    Science.gov (United States)

    Tsai, Ya-Chin; Chuang, Min-Tun

    2013-02-01

    This quasi-experimental study investigated the effect of structured peer assessment on revision of an argumentative writing. Two intact classes (N = 22, 26) were randomly assigned to be the trained and control groups. The latter received no facilitative resources, while the former participated in structured peer assessment based on Calibrated Peer Review, a web-based program purposefully designed for students to receive peer-assessment training, assess their peers' writing, and make written commentary online. At the end of the treatment, both groups revised their writing. The trained group revised their writing more extensively, outperforming the control group on frequency and type of revision, as well as the holistic quality of argumentative writing. After structured peer assessment, participants of the trained group became critical of their own work and invested more effort in spontaneous revision to produce higher-quality argumentative writing.

  14. Surgical Revision after Sacroiliac Joint Fixation or Fusion

    Science.gov (United States)

    Holt, Timothy

    2017-01-01

    Background Minimally invasive sacroiliac joint (SIJ) fusion has been shown to be safe and effective for the treatment of SIJ dysfunction. Multiple devices are available to perform SIJ fixation or fusion. Surgical revision rates after these procedures have not been directly compared. Methods We retrospectively identified all patients in our practice who underwent SIJ fixation or fusion between 2003 and 2015. Using both chart review and focused contact with individual patients, we determined the likelihood of surgical revision. Revision rates were compared using Kaplan-Meier survival analysis. Results Thirty-eight patients underwent SIJ fixation with screws and 274 patients underwent SIJ fusion using triangular titanium implants. Four-year cumulative revision rates were 30.8% for fixation and 5.7% for fusion. Conclusions In our study, SIJ fixation with screws had a much higher revision rate compared to SIJ fusion with triangular titanium implants designed for bone adherence.

  15. Early morbidity after aseptic revision hip arthroplasty in Denmark

    DEFF Research Database (Denmark)

    Lindberg-Larsen, M.; Hansen, Torben Bæk

    2014-01-01

    aseptic revision THRs from 1st October 2009 to 30th September 2011 using the Danish National Patient Registry, with additional information from the Danish Hip Arthroplasty Registry. There were 1553 procedures (1490 patients) performed in 40 centres and we divided them into total revisions, acetabular...... component revisions, femoral stem revisions and partial revisions. The mean age of the patients was 70.4 years (25 to 98) and the median hospital stay was five days (interquartile range 3 to 7). Within 90 days of surgery, the readmission rate was 18.3%, mortality rate 1.4%, re-operation rate 6.......1%, dislocation rate 7.0% and infection rate 3.0%. There were no differences in these outcomes between high- and low-volume centres. Of all readmissions, 255 (63.9%) were due to 'surgical' complications versus 144 (36.1%) 'medical' complications. Importantly, we found no differences in early morbidity across...

  16. Revising probability estimates: Why increasing likelihood means increasing impact.

    Science.gov (United States)

    Maglio, Sam J; Polman, Evan

    2016-08-01

    Forecasted probabilities rarely stay the same for long. Instead, they are subject to constant revision-moving upward or downward, uncertain events become more or less likely. Yet little is known about how people interpret probability estimates beyond static snapshots, like a 30% chance of rain. Here, we consider the cognitive, affective, and behavioral consequences of revisions to probability forecasts. Stemming from a lay belief that revisions signal the emergence of a trend, we find in 10 studies (comprising uncertain events such as weather, climate change, sex, sports, and wine) that upward changes to event-probability (e.g., increasing from 20% to 30%) cause events to feel less remote than downward changes (e.g., decreasing from 40% to 30%), and subsequently change people's behavior regarding those events despite the revised event-probabilities being the same. Our research sheds light on how revising the probabilities for future events changes how people manage those uncertain events. (PsycINFO Database Record

  17. Rural blood availability: regulations must meet ethics.

    Science.gov (United States)

    Jain, Yogesh; Kataria, Raman

    2016-01-01

    Rural physicians have been practising the technique of emergency bleeding and transfusion called Unbanked Directed (to a specific recipient) Blood Transfusion (UDBT), which has been declared illegal, to meet the need for blood in rural and inaccessible areas. As a result, a crisis has emerged in the availability of blood. Is UDBT a second rate technology for the poor and the disadvantaged? And should we not rather advocate for rapid scaling up of the establishment of blood banks in all areas? We examine the ethical issues related to blood availability in the rural areas. We argue that a regulated and licensed UDBT passes muster on the ethical principles of beneficence, lack of maleficence, justice and Swaraj. Using this issue as a case in point, we further examine the idea of what constitutes appropriate or acceptable technology. While affirming that any technology has to pass muster on a litmus test of acceptability, we discuss the difference between "ideal" and "acceptable" (but less than ideal) technology. We argue there is a dynamic push and pull between the urge to regulate and restrict the use of skills by all versus the need to communitise technology. Regulated use of UDBT will allow blood to be available where it is needed most in the foreseeable future in India.

  18. Red blood cells in retinal vascular disorders.

    Science.gov (United States)

    Agrawal, Rupesh; Sherwood, Joseph; Chhablani, Jay; Ricchariya, Ashutosh; Kim, Sangho; Jones, Philip H; Balabani, Stavroula; Shima, David

    2016-01-01

    Microvascular circulation plays a vital role in regulating physiological functions, such as vascular resistance, and maintaining organ health. Pathologies such as hypertension, diabetes, or hematologic diseases affect the microcirculation posing a significant risk to human health. The retinal vasculature provides a unique window for non-invasive visualisation of the human circulation in vivo and retinal vascular image analysis has been established to predict the development of both clinical and subclinical cardiovascular, metabolic, renal and retinal disease in epidemiologic studies. Blood viscosity which was otherwise thought to play a negligible role in determining blood flow based on Poiseuille's law up to the 1970s has now been shown to play an equally if not a more important role in controlling microcirculation and quantifying blood flow. Understanding the hemodynamics/rheology of the microcirculation and its changes in diseased states remains a challenging task; this is due to the particulate nature of blood, the mechanical properties of the cells (such as deformability and aggregability) and the complex architecture of the microvasculature. In our review, we have tried to postulate a possible role of red blood cell (RBC) biomechanical properties and laid down future framework for research related to hemorrheological aspects of blood in patients with retinal vascular disorders.

  19. Generation of red blood cells from human embryonic/induced pluripotent stem cells for blood transfusion.

    Science.gov (United States)

    Ebihara, Yasuhiro; Ma, Feng; Tsuji, Kohichiro

    2012-06-01

    Red blood cell (RBC) transfusion is necessary for many patients with emergency or hematological disorders. However, to date the supply of RBCs remains labile and dependent on voluntary donations. In addition, the transmission of infectious disease via blood transfusion from unspecified donors remains a risk. Establishing a large quantity of safe RBCs would help to address this issue. Human embryonic stem (hES) cells and the recently established human induced pluripotent stem (hiPS) cells represent potentially unlimited sources of donor-free RBCs for blood transfusion, as they can proliferate indefinitely in vitro. Extensive research has been done to efficiently generate transfusable RBCs from hES/iPS cells. Nevertheless, a number of challenges must be overcome before the clinical usage of hES/iPS cell-derived RBCs can become a reality.

  20. High Blood Pressure Fact Sheet

    Science.gov (United States)

    ... High Blood Pressure Salt Cholesterol Million Hearts® WISEWOMAN High Blood Pressure Fact Sheet Language: English Español (Spanish) Recommend on ... time. High blood pressure is also called hypertension. High Blood Pressure in the United States Having high blood pressure ...

  1. Home monitoring of blood pressure

    OpenAIRE

    McGrath, Barry P.

    2015-01-01

    Home blood pressure monitoring is the self-measurement of blood pressure by patients. In the diagnosis and management of high blood pressure it is complementary to 24-hour ambulatory blood pressure monitoring and clinic blood pressure measurements. Home monitoring can also help to identify white-coat and masked hypertension.

  2. Survival after blood transfusion

    DEFF Research Database (Denmark)

    Kamper-Jørgensen, Mads; Ahlgren, Martin; Rostgaard, Klaus

    2008-01-01

    of transfusion recipients in Denmark and Sweden followed for up to 20 years after their first blood transfusion. Main outcome measure was all-cause mortality. RESULTS: A total of 1,118,261 transfusion recipients were identified, of whom 62.0 percent were aged 65 years or older at the time of their first...... the SMR remained significantly 1.3-fold increased. CONCLUSION: The survival and relative mortality patterns among blood transfusion recipients were characterized with unprecedented detail and precision. Our results are relevant to assessments of the consequences of possible transfusion-transmitted disease...... as well as for cost-benefit estimation of new blood safety interventions....

  3. Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test.

    Science.gov (United States)

    Bowen, Damian E; Whitwell, James H; Lillford, Lucinda; Henderson, Debbie; Kidd, Darren; Mc Garry, Sarah; Pearce, Gareth; Beevers, Carol; Kirkland, David J

    2011-05-18

    With the publication of revised draft ICH guidelines (Draft ICH S2), there is scope and potential to establish a combined multi-end point in vivo assay to alleviate the need for multiple in vivo assays, thereby reducing time, cost and use of animals. Presented here are the results of an evaluation trial in which the bone-marrow and peripheral blood (via MicroFlow(®) flow cytometry) micronucleus tests (looking at potential chromosome breakage and whole chromosome loss) in developing erythrocytes or young reticulocytes were combined with the Comet assay (measuring DNA strand-breakage), in stomach, liver and blood lymphocytes. This allowed a variety of potential target tissues (site of contact, site of metabolism and peripheral distribution) to be assessed for DNA damage. This combination approach was performed with minimal changes to the standard and regulatory recommended sampling times for the stand-alone assays. A series of eight in vivo genotoxins (2-acetylaminofluorene, benzo[a]pyrene, carbendazim, cyclophosphamide, dimethylnitrosamine, ethyl methanesulfonate, ethyl nitrosourea and mitomycin C), which are known to act via different modes of action (direct- and indirect-acting clastogens, alkylating agents, gene mutagens, cross-linking and aneugenic compounds) were tested. Male rats were dosed at 0, 24 and 45 h, and bone marrow and peripheral blood (micronucleus endpoint), liver, whole blood and stomach (Comet endpoint) were sampled at three hours after the last dose. Comet and micronucleus responses were as expected based on available data for conventional (acute) stand-alone assays. All compounds were detected as genotoxic in at least one of the endpoints. The importance of evaluating both endpoints was highlighted by the uniquely positive responses for certain chemicals (benzo[a]pyrene and 2-acetylaminofluorene) with the Comet endpoint and certain other chemicals (carbendazim and mitomycin C) with the micronucleus endpoint. The data generated from these

  4. Prenatal diagnosis of trisomy 13 on fetal cells obtained from maternal blood after minor enrichment

    NARCIS (Netherlands)

    Oosterwijk, JC; Mesker, WE; Ouwerkerk-Van Velzen, MCM; Knepfle, CFHM; Wiesmeijer, KC; Beverstock, GC; Van Ommen, GJB; Tanke, HJ; Kanhai, HHH

    1998-01-01

    In a pilot study to establish fetal nucleated red blood cell (NRBC) detection in maternal blood, trisomy 13 was diagnosed by FISH analysis at 11 weeks' gestation. The NRBCs were detected after a single-step ficoll density gradient enrichment. In blood samples taken both before and after CVS, 52 and

  5. 75 FR 22813 - Guidance for Industry: Requalification Method for Reentry of Blood Donors Deferred Because of...

    Science.gov (United States)

    2010-04-30

    ...The Food and Drug Administration (FDA) is announcing the availability of a document entitled ``Guidance for Industry: Requalification Method for Reentry of Blood Donors Deferred Because of Reactive Test Results for Antibody to Hepatitis B Core Antigen (Anti- HBc),'' dated May 2010. The guidance document provides recommendations to establishments that collect Whole Blood or blood components......

  6. The revised solar array synthesis computer program

    Science.gov (United States)

    1970-01-01

    The Revised Solar Array Synthesis Computer Program is described. It is a general-purpose program which computes solar array output characteristics while accounting for the effects of temperature, incidence angle, charged-particle irradiation, and other degradation effects on various solar array configurations in either circular or elliptical orbits. Array configurations may consist of up to 75 solar cell panels arranged in any series-parallel combination not exceeding three series-connected panels in a parallel string and no more than 25 parallel strings in an array. Up to 100 separate solar array current-voltage characteristics, corresponding to 100 equal-time increments during the sunlight illuminated portion of an orbit or any 100 user-specified combinations of incidence angle and temperature, can be computed and printed out during one complete computer execution. Individual panel incidence angles may be computed and printed out at the user's option.

  7. A Revised Collection of Sunspot Group Numbers

    CERN Document Server

    Vaquero, J M; Carrasco, V M S; Clette, F; Lefèvre, L; Gallego, M C; Arlt, R; Aparicio, A J P; Richard, J -G; Howe, R

    2016-01-01

    We describe a revised collection of the number of sunspot groups from 1610 to the present. This new collection is based on the work of Hoyt and Schatten (Solar Phys. 179, 189, 1998). The main changes are the elimination of a considerable number of observations during the Maunder Minimum (hereafter, MM) and the inclusion of several long series of observations. Numerous minor changes are also described. Moreover, we have calculated the active-day percentage during the MM from this new collection as a reliable index of the solar activity. Thus, the level of solar activity obtained in this work is greater than the level obtained using the original Hoyt and Schatten data, although it remains compatible with a grand minimum of solar activity. The new collection is available in digital format.

  8. Revision of the afrotropical oberthuerellinae (cynipoidea, liopteridae).

    Science.gov (United States)

    Buffington, Matthew L; van Noort, Simon

    2012-01-01

    The Afrotropical Oberthuerellinae are revised, and new dichotomous and multi-entry keys to the species of Oberthuerella, Tessmannella, and Xenocynips are provided. All previously described species in these genera are redescribed; descriptions are augmented by color images of the holotype for each species. The following 11 species are described as new: Oberthuerella cyclopia Buffington & van Noort; Oberthuerella eschara Buffington & van Noort; Oberthuerella kibalensis van Noort & Buffington; Oberthuerella pardolatus Buffington & van Noort; Oberthuerella sharkeyi Buffington & van Noort; Oberthuerella simba Buffington & van Noort; Tessmannella copelandi Buffington & van Noort; Tessmannella kiplingi Buffington & van Noort; Tessmannella roberti Buffington & van Noort; Xenocynips rhothion Buffington & van Noort; and Xenocynips ronquisti Buffington & van Noort. We provide identification keys to the genera and species occurring in the Afrotropical region. Online dichotomous and interactive Lucid keys to genera and species are available at http://www.waspweb.org/Cynipoidea/Keys/index.htm.

  9. The Kerr-Schild ansatz revised

    CERN Document Server

    Bini, Donato; Kerr, Roy P

    2014-01-01

    Kerr-Schild metrics have been introduced as a linear superposition of the flat spacetime metric and a squared null vector field, say $\\boldsymbol{k}$, multiplied by some scalar function, say $H$. The basic assumption which led to Kerr solution was that $\\boldsymbol{k}$ be both geodesic and shearfree. This condition is relaxed here and Kerr-Schild ansatz is revised by treating Kerr-Schild metrics as {\\it exact linear perturbations} of Minkowski spacetime. The scalar function $H$ is taken as the perturbing function, so that Einstein's field equations are solved order by order in powers of $H$. It turns out that the congruence must be geodesic and shearfree as a consequence of third and second order equations, leading to an alternative derivation of Kerr solution.

  10. A Review of Criticality Accidents 2000 Revision

    Energy Technology Data Exchange (ETDEWEB)

    Thomas P. McLaughlin; Shean P. Monahan; Norman L. Pruvost; Vladimir V. Frolov; Boris G. Ryazanov; Victor I. Sviridov

    2000-05-01

    Criticality accidents and the characteristics of prompt power excursions are discussed. Sixty accidental power excursions are reviewed. Sufficient detail is provided to enable the reader to understand the physical situation, the chemistry and material flow, and when available the administrative setting leading up to the time of the accident. Information on the power history, energy release, consequences, and causes are also included when available. For those accidents that occurred in process plants, two new sections have been included in this revision. The first is an analysis and summary of the physical and neutronic features of the chain reacting systems. The second is a compilation of observations and lessons learned. Excursions associated with large power reactors are not included in this report.

  11. Revision of monotypic genus Llavea (Cryptogrammoideae: Pteridaceae

    Directory of Open Access Journals (Sweden)

    Mónica Palacios-Rios

    2016-12-01

    Full Text Available Llavea Lag. is a genus of Cryptogrammoideae (Pteridaceae, whose only species is distributed from southern United States and Mexico to Guatemala and Costa Rica, although it lives mainly in Mesoamerica, inhabiting preferably calcicolous habitats associated with forests and mountains. The genus is easily recognized by the presence of fertile leaves hemi-dimorphic, with the fertile apical portion with longer and narrower segments than the sterile ones, with strongly revolute margin, and rhizome scales bicolorous, shiny, and black. This paper presents a revision of the genus, nomenclatural issues are resolved, and and palynological morphological diversity are reviewed, as well as its distribution, phenology, ecology, and applications, based on field and herbarium specimens studies. In addition, two names related to Llavea, Allosorus karwinskii Kunze and Ceratodactylis osmundioides J. Sm., were lectotypified.

  12. Ventriculoperitoneal shunt complications needing shunt revision in children: A review of 5 years of experience with 48 revisions

    Directory of Open Access Journals (Sweden)

    Rajendra K Ghritlaharey

    2012-01-01

    Full Text Available Background: The aim of this study was to review the management of ventriculoperitoneal (VP shunt complications in children. Patients and Methods: During the last 5 years (January 1, 2006 to December 31, 2010, 236 VP shunt operations were performed in children under 12 years of age; of these, 40 (16.94% developed shunt complications and those who underwent VP shunt revisions were studied. Results: This prospective study included 40 (28 boys and 12 girls children and required 48 shunt revisions. Complications following VP shunts that required shunt revisions were peritoneal catheter/peritoneal end malfunction (18, shunt/shunt tract infections (7, extrusion of peritoneal catheter through anus (5, ventricular catheter malfunction (4, cerebrospinal fluid (CSF leak from abdominal wound (4, shunt system failure (2, ventricular end/shunt displacement (2, CSF pseudocysts peritoneal cavity (2, extrusion of peritoneal catheter from neck, chest, abdominal scar and through umbilicus, one each. Four-fifth of these shunt complications occurred within 6 months of previous surgery. Surgical procedures done during shunt revisions in order of frequency were revision of peritoneal part of shunt (27, 56.25%, revision of entire shunt system (6, 12.5%, extra ventricular drainage and delayed re-shunt (5, 10.41%, shunt removal and delayed re-shunt (5, 10.41%, opposite side shunting (2, 4.16%, cysts excision and revision of peritoneal catheter (2, 4.16% and revision of ventricular catheter (1, 2.08%. The mortalities following VP shunt operations were 44 (18.64% and following shunt revisions were 4 (10%. Conclusions: VP shunt done for hydrocephalus in children is not only prone for complications and need for revision surgery but also associated with considerable mortality.

  13. Some considerations for establishing seismic design criteria for nuclear plant piping

    Energy Technology Data Exchange (ETDEWEB)

    Chen, W.P. [Energy Technology Engineering Center, Canoga Park, CA (United States); Chokshi, N.C. [Nuclear Regulatory Commission, Washington, DC (United States)

    1997-01-01

    The Energy Technology Engineering Center (ETEC) is providing assistance to the U.S. NRC in developing regulatory positions on the seismic analysis of piping. As part of this effort, ETEC previously performed reviews of the ASME Code, Section III piping seismic design criteria as revised by the 1994 Addenda. These revised criteria were based on evaluations by the ASME Special Task Group on Integrated Piping Criteria (STGIPC) and the Technical Core Group (TCG) of the Advanced Reactor Corporation (ARC) of the earlier joint Electric Power Research Institute (EPRI)/NRC Piping & Fitting Dynamic Reliability (PFDR) program. Previous ETEC evaluations reported at the 23rd WRSM of seismic margins associated with the revised criteria are reviewed. These evaluations had concluded, in part, that although margins for the timed PFDR tests appeared acceptable (>2), margins in detuned tests could be unacceptable (<1). This conclusion was based primarily on margin reduction factors (MRFs) developed by the ASME STGIPC and ARC/TCG from realistic analyses of PFDR test 36. This paper reports more recent results including: (1) an approach developed for establishing appropriate seismic margins based on PRA considerations, (2) independent assessments of frequency effects on margins, (3) the development of margins based on failure mode considerations, and (4) the implications of Code Section III rules for Section XI.

  14. Revised spatially distributed global livestock emissions

    Science.gov (United States)

    Asrar, G.; Wolf, J.; West, T. O.

    2015-12-01

    Livestock play an important role in agricultural carbon cycling through consumption of biomass and emissions of methane. Quantification and spatial distribution of methane and carbon dioxide produced by livestock is needed to develop bottom-up estimates for carbon monitoring. These estimates serve as stand-alone international emissions estimates, as input to global emissions modeling, and as comparisons or constraints to flux estimates from atmospheric inversion models. Recent results for the US suggest that the 2006 IPCC default coefficients may underestimate livestock methane emissions. In this project, revised coefficients were calculated for cattle and swine in all global regions, based on reported changes in body mass, quality and quantity of feed, milk production, and management of living animals and manure for these regions. New estimates of livestock methane and carbon dioxide emissions were calculated using the revised coefficients and global livestock population data. Spatial distribution of population data and associated fluxes was conducted using the MODIS Land Cover Type 5, version 5.1 (i.e. MCD12Q1 data product), and a previously published downscaling algorithm for reconciling inventory and satellite-based land cover data at 0.05 degree resolution. Preliminary results for 2013 indicate greater emissions than those calculated using the IPCC 2006 coefficients. Global total enteric fermentation methane increased by 6%, while manure management methane increased by 38%, with variation among species and regions resulting in improved spatial distributions of livestock emissions. These new estimates of total livestock methane are comparable to other recently reported studies for the entire US and the State of California. These new regional/global estimates will improve the ability to reconcile top-down and bottom-up estimates of methane production as well as provide updated global estimates for use in development and evaluation of Earth system models.

  15. Revision of Failed Artroscopic Bankart Repairs

    Science.gov (United States)

    Muiño, José María Silberberg; Gimenez, Martín Alejandro; Salvucci, Mauro Gabriel Maroa; Ferro, Diego; Rullan, Ramón Muiña

    2017-01-01

    Objectives: To present our functional outcomes from patients treated arthroscopically for a failed Bankart repair, using suture anchors and capsulolabral tissue only. Methods: Series of 22 patients presented with a recurrence of instability after a previous stabilization surgery (3 Latarjet, Bankart 19). We treated them by a an all-arthroscopic procedure, avoiding bone grafts, when glenoid track was found to be enough to proceed. The failure was associated with trauma in 11 patients, a non-anatomic repair in 6 patients, capsular laxity in 4 patients and a non-union of the coracoid graft in 1 patient. Revision surgery included: Bankart repair with anchors in 17 cases, a posterior-inferior capsulo-labral plication in one case, and 5 remplissages. In 4 cases subscapularis augmentation was used because of poor capsular quality. Screw removal was necessary when treating the non-union case. Patients were followed-up by a minimum of 23 months (range 23-26), and evaluated by the UCLA Test, SS test and Rowe score. Results: Thirteen patients had an excellent result, 6 good, 2 satisfactory and one bad result, according to UCLA score. The mean Rowe score was 90.4, at final follow up. The Simple Shoulder Test went from an 8 preoperative to an 11 postoperative, mean scores. 19 of 22 patients returned to the same level of activity prior to the injury. Complications: recurrence in 2 cases, subluxation in 2 and one shoulder stiffness that required an arthrolysis. Conclusion: An arthroscopic revision surgery, after a failed Bankart repair, presents satisfactory results in selected patients. Arthroscopic vision allows a correct diagnosis of injuries as possible causes of failure and subsequent treatment.

  16. CUSTOMIZED ACETABULAR COMPONENTS IN REVISION HIP ARTHROPLASTY

    Directory of Open Access Journals (Sweden)

    G. M. Kavalersky

    2016-01-01

    Full Text Available In recent years, there is a trend of increasing demand for revision hip arthroplasty. Among these patients there are many with complex acetabular defects, including patients with pelvic discontinuity. To ensure stability for revised acetabular components in such cases becomes a challenging or unachievable task. Such defects give indications for printing customized tri-flange acetabular component. The authors analysed own experience of creating and applying custom made acetabular components in 3 patients with complex acetabular defects. Material and methods. Among the patients there were 2 women and 1 man. Average age was 60,3±19,4 years (38 to 78 years. Two patients had III B defects with pelvic discontinuity and one patient had III A defect by Paprosky classification. As the first step, the authors in collaboration with engineers printed a plaster full size pelvic 3D model, as the second step a customized tri-flange acetabular component was designed and printed. Harris Hip Score was evaluated preoperatively and 3 months postoperatively. Results. Average follow-up period was 5,3±2,5 months (3 to 8 months. The authors observed no cases of implant loosening, dislocation or deep periprosthetic infection. Average Harris Hip Score before surgery was 27,13 and after surgery – 74,1 indicating a significant improvement in 3 months postoperatively. Conclusion. Indications for use of individual acetabular components in reported patients correspond to indications formulated by Berasi et al. The authors obtained encouraging early follow-up outcomes that correspond to data of other authors. In one patient certain difficulties were reported due to insufficient pelvic distraction. Component’s flanges prevented achieving adequate pelvic distraction. Nevertheless, good primary stability was achieved. Modern software and 3D metal printers can significantly reduce the production cost of customized acetabular components. Application of this technology can be

  17. 20 CFR 900.2 - Establishment.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Establishment. 900.2 Section 900.2 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES STATEMENT OF ORGANIZATION § 900.2 Establishment. The Joint Board has been established by the Secretary of Labor and the Secretary of the Treasury pursuant...

  18. Hyperglycemia (High Blood Glucose)

    Medline Plus

    Full Text Available ... Complications DKA (Ketoacidosis) & Ketones Kidney Disease (Nephropathy) Gastroparesis Mental Health Step On Up Treatment & Care Blood Glucose Testing Medication Doctors, Nurses & More Oral Health & Hygiene Women A1C Insulin Pregnancy ...

  19. Cord-Blood Banking

    Science.gov (United States)

    ... blood banks may capitalize on the fears of vulnerable new parents by providing misleading information about the statistics of stem cell transplants. Parents of children of ethnic or racial minorities, adopted children, or ...

  20. High Blood Pressure

    Science.gov (United States)

    ... may have tax advantages for you. Workplace giving Workplace giving Find a list of the most common ... pressure and cholesterol. Exercise can also help relieve stress, another common cause of high blood pressure. To ...