Dynamic analysis of pedestrian crossing behaviors on traffic flow at unsignalized mid-block crosswalks

Science.gov (United States)

Liu, Gang; He, Jing; Luo, Zhiyong; Yang, Wunian; Zhang, Xiping

2015-05-01

It is important to study the effects of pedestrian crossing behaviors on traffic flow for solving the urban traffic jam problem. Based on the Nagel-Schreckenberg (NaSch) traffic cellular automata (TCA) model, a new one-dimensional TCA model is proposed considering the uncertainty conflict behaviors between pedestrians and vehicles at unsignalized mid-block crosswalks and defining the parallel updating rules of motion states of pedestrians and vehicles. The traffic flow is simulated for different vehicle densities and behavior trigger probabilities. The fundamental diagrams show that no matter what the values of vehicle braking probability, pedestrian acceleration crossing probability, pedestrian backing probability and pedestrian generation probability, the system flow shows the "increasing-saturating-decreasing" trend with the increase of vehicle density; when the vehicle braking probability is lower, it is easy to cause an emergency brake of vehicle and result in great fluctuation of saturated flow; the saturated flow decreases slightly with the increase of the pedestrian acceleration crossing probability; when the pedestrian backing probability lies between 0.4 and 0.6, the saturated flow is unstable, which shows the hesitant behavior of pedestrians when making the decision of backing; the maximum flow is sensitive to the pedestrian generation probability and rapidly decreases with increasing the pedestrian generation probability, the maximum flow is approximately equal to zero when the probability is more than 0.5. The simulations prove that the influence of frequent crossing behavior upon vehicle flow is immense; the vehicle flow decreases and gets into serious congestion state rapidly with the increase of the pedestrian generation probability.

Decreased function of survival motor neuron protein impairs endocytic pathways.

Science.gov (United States)

Dimitriadi, Maria; Derdowski, Aaron; Kalloo, Geetika; Maginnis, Melissa S; O'Hern, Patrick; Bliska, Bryn; Sorkaç, Altar; Nguyen, Ken C Q; Cook, Steven J; Poulogiannis, George; Atwood, Walter J; Hall, David H; Hart, Anne C

2016-07-26

Spinal muscular atrophy (SMA) is caused by depletion of the ubiquitously expressed survival motor neuron (SMN) protein, with 1 in 40 Caucasians being heterozygous for a disease allele. SMN is critical for the assembly of numerous ribonucleoprotein complexes, yet it is still unclear how reduced SMN levels affect motor neuron function. Here, we examined the impact of SMN depletion in Caenorhabditis elegans and found that decreased function of the SMN ortholog SMN-1 perturbed endocytic pathways at motor neuron synapses and in other tissues. Diminished SMN-1 levels caused defects in C. elegans neuromuscular function, and smn-1 genetic interactions were consistent with an endocytic defect. Changes were observed in synaptic endocytic proteins when SMN-1 levels decreased. At the ultrastructural level, defects were observed in endosomal compartments, including significantly fewer docked synaptic vesicles. Finally, endocytosis-dependent infection by JC polyomavirus (JCPyV) was reduced in human cells with decreased SMN levels. Collectively, these results demonstrate for the first time, to our knowledge, that SMN depletion causes defects in endosomal trafficking that impair synaptic function, even in the absence of motor neuron cell death.

Gliadin peptide P31-43 localises to endocytic vesicles and interferes with their maturation.

Directory of Open Access Journals (Sweden)

Maria Vittoria Barone

Full Text Available BACKGROUND: Celiac Disease (CD is both a frequent disease (1:100 and an interesting model of a disease induced by food. It consists in an immunogenic reaction to wheat gluten and glutenins that has been found to arise in a specific genetic background; however, this reaction is still only partially understood. Activation of innate immunity by gliadin peptides is an important component of the early events of the disease. In particular the so-called "toxic" A-gliadin peptide P31-43 induces several pleiotropic effects including Epidermal Growth Factor Receptor (EGFR-dependent actin remodelling and proliferation in cultured cell lines and in enterocytes from CD patients. These effects are mediated by delayed EGFR degradation and prolonged EGFR activation in endocytic vesicles. In the present study we investigated the effects of gliadin peptides on the trafficking and maturation of endocytic vesicles. METHODS/PRINCIPAL FINDINGS: Both P31-43 and the control P57-68 peptide labelled with fluorochromes were found to enter CaCo-2 cells and interact with the endocytic compartment in pulse and chase, time-lapse, experiments. P31-43 was localised to vesicles carrying early endocytic markers at time points when P57-68-carrying vesicles mature into late endosomes. In time-lapse experiments the trafficking of P31-43-labelled vesicles was delayed, regardless of the cargo they were carrying. Furthermore in celiac enterocytes, from cultured duodenal biopsies, P31-43 trafficking is delayed in early endocytic vesicles. A sequence similarity search revealed that P31-43 is strikingly similar to Hrs, a key molecule regulating endocytic maturation. A-gliadin peptide P31-43 interfered with Hrs correct localisation to early endosomes as revealed by western blot and immunofluorescence microscopy. CONCLUSIONS: P31-43 and P57-68 enter cells by endocytosis. Only P31-43 localises at the endocytic membranes and delays vesicle trafficking by interfering with Hrs

Pre-cancerous changes in urothelial endocytic vesicle leakage, fatty acid composition, and As and associated element concentrations after arsenic exposure

International Nuclear Information System (INIS)

Grasso, E.J.; Bongiovanni, G.A.; Perez, R.D.; Calderon, R.O.

2011-01-01

The urothelium covering the luminal surface of the urinary bladder has developed an efficient permeability barrier that protects it against the back-flow of toxins eliminated in the urine. The subapical endocytic vesicles containing the urinary bladder fluid phase are formed during the micturition cycle by endocytosis processes of the superficial cells. In normal conditions, the permeability barrier of the endocytic vesicles blocks the passage of the fluid phase to the cellular cytoplasm and the fluid is recycled to the bladder lumen. The aim of this work was to investigate the alteration of the endocytic vesicle membrane permeability barrier to toxins such as iAs (inorganic arsenic) administered in drinking water. By using an induced endocytosis model and the fluorescence requenching technique, it is shown that the exposure of rats to ingestion of water containing iAs not only induced pre-cancerous morphological changes, but allowed the differential leakage of an endocytosed fluorescent marker, HPTS, and its quencher, DPX, (hydroxypyrene-1,3,6-trisulfonic acid and p-xylene-bis-pyridinium bromide, respectively) out of the vesicular lumen. The leakage of the cationic DPX was almost complete, while the release of the anionic HPTS molecule was partial and higher in arsenic-treated-rats than in controls. Such membrane alteration would allow the toxins to elude the permeability barrier and to leak out of the endocytic vesicles, thus establishing a 'bypass' to the permeability barrier. The retention of As in the urinary bladder, assessed by synchrotron radiation X-ray fluorescence spectrometry (SR-μXRF), was lower than the kidney accumulation of arsenic previously observed by our group and was accompanied by altered concentrations of K, Ca, Fe, Cu and Zn, all ions related to cellular metabolism. The results support the hypothesis that low amounts of endocytosed As can accumulate in the interior of the urothelial superficial cells and initiate the cytotoxic effects

dOCRL maintains immune cell quiescence by regulating endosomal traffic.

Directory of Open Access Journals (Sweden)

Steven J Del Signore

2017-10-01

Full Text Available Lowe Syndrome is a developmental disorder characterized by eye, kidney, and neurological pathologies, and is caused by mutations in the phosphatidylinositol-5-phosphatase OCRL. OCRL plays diverse roles in endocytic and endolysosomal trafficking, cytokinesis, and ciliogenesis, but it is unclear which of these cellular functions underlie specific patient symptoms. Here, we show that mutation of Drosophila OCRL causes cell-autonomous activation of hemocytes, which are macrophage-like cells of the innate immune system. Among many cell biological defects that we identified in docrl mutant hemocytes, we pinpointed the cause of innate immune cell activation to reduced Rab11-dependent recycling traffic and concomitantly increased Rab7-dependent late endosome traffic. Loss of docrl amplifies multiple immune-relevant signals, including Toll, Jun kinase, and STAT, and leads to Rab11-sensitive mis-sorting and excessive secretion of the Toll ligand Spåtzle. Thus, docrl regulation of endosomal traffic maintains hemocytes in a poised, but quiescent state, suggesting mechanisms by which endosomal misregulation of signaling may contribute to symptoms of Lowe syndrome.

Differential effects of EGFR ligands on endocytic sorting of the receptor

DEFF Research Database (Denmark)

Roepstorff, Kirstine; Grandal, Michael Vibo; Henriksen, Lasse

2009-01-01

signalling and is a more potent mitogen than EGF. In addition to EGF and TGF-alpha, five EGFR ligands have been identified. Although many of these ligands are upregulated in cancers, very little is known about their effect on EGFR trafficking. We have compared the effect of six different ligands on endocytic...... trafficking of EGFR. We find that, whereas they all stimulate receptor internalization, they have very diverse effects on endocytic sorting. Heparin-binding EGF-like growth factor and Betacellulin target all EGFRs for lysosomal degradation. In contrast, TGF-alpha and epiregulin lead to complete receptor...

A Coincidence Detection Mechanism Controls PX-BAR Domain-Mediated Endocytic Membrane Remodeling via an Allosteric Structural Switch.

Science.gov (United States)

Lo, Wen-Ting; Vujičić Žagar, Andreja; Gerth, Fabian; Lehmann, Martin; Puchkov, Dymtro; Krylova, Oxana; Freund, Christian; Scapozza, Leonardo; Vadas, Oscar; Haucke, Volker

2017-11-20

Clathrin-mediated endocytosis occurs by bending and remodeling of the membrane underneath the coat. Bin-amphiphysin-rvs (BAR) domain proteins are crucial for endocytic membrane remodeling, but how their activity is spatiotemporally controlled is largely unknown. We demonstrate that the membrane remodeling activity of sorting nexin 9 (SNX9), a late-acting endocytic PX-BAR domain protein required for constriction of U-shaped endocytic intermediates, is controlled by an allosteric structural switch involving coincident detection of the clathrin adaptor AP2 and phosphatidylinositol-3,4-bisphosphate (PI(3,4)P 2 ) at endocytic sites. Structural, biochemical, and cell biological data show that SNX9 is autoinhibited in solution. Binding to PI(3,4)P 2 via its PX-BAR domain, and concomitant association with AP2 via sequences in the linker region, releases SNX9 autoinhibitory contacts to enable membrane constriction. Our results reveal a mechanism for restricting the latent membrane remodeling activity of BAR domain proteins to allow spatiotemporal coupling of membrane constriction to the progression of the endocytic pathway. Copyright © 2017 Elsevier Inc. All rights reserved.

Endocytic Pathways Involved in Filovirus Entry: Advances, Implications and Future Directions

Directory of Open Access Journals (Sweden)

Suchita Bhattacharyya

2012-12-01

Full Text Available Detailed knowledge of the host-virus interactions that accompany filovirus entry into cells is expected to identify determinants of viral virulence and host range, and to yield targets for the development of antiviral therapeutics. While it is generally agreed that filovirus entry into the host cytoplasm requires viral internalization into acidic endosomal compartments and proteolytic cleavage of the envelope glycoprotein by endo/lysosomal cysteine proteases, our understanding of the specific endocytic pathways co-opted by filoviruses remains limited. This review addresses the current knowledge on cellular endocytic pathways implicated in filovirus entry, highlights the consensus as well as controversies, and discusses important remaining questions.

Rationally Engineering Phototherapy Modules of Eosin-Conjugated Responsive Polymeric Nanocarriers via Intracellular Endocytic pH Gradients.

Science.gov (United States)

Liu, Guhuan; Hu, Jinming; Zhang, Guoying; Liu, Shiyong

2015-07-15

Spatiotemporal switching of respective phototherapy modes at the cellular level with minimum side effects and high therapeutic efficacy is a major challenge for cancer phototherapy. Herein we demonstrate how to address this issue by employing photosensitizer-conjugated pH-responsive block copolymers in combination with intracellular endocytic pH gradients. At neutral pH corresponding to extracellular and cytosol milieu, the copolymers self-assemble into micelles with prominently quenched fluorescence emission and low (1)O2 generation capability, favoring a highly efficient photothermal module. Under mildly acidic pH associated with endolysosomes, protonation-triggered micelle-to-unimer transition results in recovered emission and enhanced photodynamic (1)O2 efficiency, which synergistically actuates release of encapsulated drugs, endosomal escape, and photochemical internalization processes.

Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis.

Directory of Open Access Journals (Sweden)

Natasha Chaudhary

2014-04-01

Full Text Available Several studies have suggested crosstalk between different clathrin-independent endocytic pathways. However, the molecular mechanisms and functional relevance of these interactions are unclear. Caveolins and cavins are crucial components of caveolae, specialized microdomains that also constitute an endocytic route. Here we show that specific caveolar proteins are independently acting negative regulators of clathrin-independent endocytosis. Cavin-1 and Cavin-3, but not Cavin-2 or Cavin-4, are potent inhibitors of the clathrin-independent carriers/GPI-AP enriched early endosomal compartment (CLIC/GEEC endocytic pathway, in a process independent of caveola formation. Caveolin-1 (CAV1 and CAV3 also inhibit the CLIC/GEEC pathway upon over-expression. Expression of caveolar protein leads to reduction in formation of early CLIC/GEEC carriers, as detected by quantitative electron microscopy analysis. Furthermore, the CLIC/GEEC pathway is upregulated in cells lacking CAV1/Cavin-1 or with reduced expression of Cavin-1 and Cavin-3. Inhibition by caveolins can be mimicked by the isolated caveolin scaffolding domain and is associated with perturbed diffusion of lipid microdomain components, as revealed by fluorescence recovery after photobleaching (FRAP studies. In the absence of cavins (and caveolae CAV1 is itself endocytosed preferentially through the CLIC/GEEC pathway, but the pathway loses polarization and sorting attributes with consequences for membrane dynamics and endocytic polarization in migrating cells and adult muscle tissue. We also found that noncaveolar Cavin-1 can act as a modulator for the activity of the key regulator of the CLIC/GEEC pathway, Cdc42. This work provides new insights into the regulation of noncaveolar clathrin-independent endocytosis by specific caveolar proteins, illustrating multiple levels of crosstalk between these pathways. We show for the first time a role for specific cavins in regulating the CLIC/GEEC pathway, provide

Endocytic collagen degradation

DEFF Research Database (Denmark)

Madsen, Daniel H.; Jürgensen, Henrik J.; Ingvarsen, Signe Ziir

2012-01-01

it crucially important to understand both the collagen synthesis and turnover mechanisms in this condition. Here we show that the endocytic collagen receptor, uPARAP/Endo180, is a major determinant in governing the balance between collagen deposition and degradation. Cirrhotic human livers displayed a marked...... up-regulation of uPARAP/Endo180 in activated fibroblasts and hepatic stellate cells located close to the collagen deposits. In a hepatic stellate cell line, uPARAP/Endo180 was shown to be active in, and required for, the uptake and intracellular degradation of collagen. To evaluate the functional...... groups of mice clearly revealed a fibrosis protective role of uPARAP/Endo180. This effect appeared to directly reflect the activity of the collagen receptor, since no compensatory events were noted when comparing the mRNA expression profiles of the two groups of mice in an array system focused on matrix-degrading...

The minute virus of mice exploits different endocytic pathways for cellular uptake

International Nuclear Information System (INIS)

Garcin, Pierre O.; Panté, Nelly

2015-01-01

The minute virus of mice, prototype strain (MVMp), is a non-enveloped, single-stranded DNA virus of the family Parvoviridae. Unlike other parvoviruses, the mechanism of cellular uptake of MVMp has not been studied in detail. We analyzed MVMp endocytosis in mouse LA9 fibroblasts and a tumor cell line derived from epithelial–mesenchymal transition through polyomavirus middle T antigen transformation in transgenic mice. By a combination of immunofluorescence and electron microscopy, we found that MVMp endocytosis occurs at the leading edge of migrating cells in proximity to focal adhesion sites. By using drug inhibitors of various endocytic pathways together with immunofluorescence microscopy and flow cytometry analysis, we discovered that MVMp can use a number of endocytic pathways, depending on the host cell type. At least three different mechanisms were identified: clathrin-, caveolin-, and clathrin-independent carrier-mediated endocytosis, with the latter occurring in transformed cells but not in LA9 fibroblasts. - Highlights: • MVMp uptake takes place at the leading edge of migrating cells. • MVMp exploits a variety of endocytic pathways. • MVMp could use clathrin- and caveolin-mediated endocytosis. • MVMp could also use clathrin-independent carriers for cellular uptake

The minute virus of mice exploits different endocytic pathways for cellular uptake

Energy Technology Data Exchange (ETDEWEB)

Garcin, Pierre O.; Panté, Nelly, E-mail: pante@zoology.ubc.ca

2015-08-15

The minute virus of mice, prototype strain (MVMp), is a non-enveloped, single-stranded DNA virus of the family Parvoviridae. Unlike other parvoviruses, the mechanism of cellular uptake of MVMp has not been studied in detail. We analyzed MVMp endocytosis in mouse LA9 fibroblasts and a tumor cell line derived from epithelial–mesenchymal transition through polyomavirus middle T antigen transformation in transgenic mice. By a combination of immunofluorescence and electron microscopy, we found that MVMp endocytosis occurs at the leading edge of migrating cells in proximity to focal adhesion sites. By using drug inhibitors of various endocytic pathways together with immunofluorescence microscopy and flow cytometry analysis, we discovered that MVMp can use a number of endocytic pathways, depending on the host cell type. At least three different mechanisms were identified: clathrin-, caveolin-, and clathrin-independent carrier-mediated endocytosis, with the latter occurring in transformed cells but not in LA9 fibroblasts. - Highlights: • MVMp uptake takes place at the leading edge of migrating cells. • MVMp exploits a variety of endocytic pathways. • MVMp could use clathrin- and caveolin-mediated endocytosis. • MVMp could also use clathrin-independent carriers for cellular uptake.

Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells.

Directory of Open Access Journals (Sweden)

Cheng-Feng Chiang

Full Text Available Andes virus (ANDV is the major cause of hantavirus pulmonary syndrome (HPS in South America. Despite a high fatality rate (up to 40%, no vaccines or antiviral therapies are approved to treat ANDV infection. To understand the role of endocytic pathways in ANDV infection, we used 3 complementary approaches to identify cellular factors required for ANDV entry into human lung microvascular endothelial cells. We screened an siRNA library targeting 140 genes involved in membrane trafficking, and identified 55 genes required for ANDV infection. These genes control the major endocytic pathways, endosomal transport, cell signaling, and cytoskeleton rearrangement. We then used infectious ANDV and retroviral pseudovirions to further characterize the possible involvement of 9 of these genes in the early steps of ANDV entry. In addition, we used markers of cellular endocytosis along with chemical inhibitors of known endocytic pathways to show that ANDV uses multiple routes of entry to infect target cells. These entry mechanisms are mainly clathrin-, dynamin-, and cholesterol-dependent, but can also occur via a clathrin-independent manner.

The HPV16 E5 oncogene inhibits endocytic trafficking

DEFF Research Database (Denmark)

Thomsen, P; van Deurs, B; Norrild, B

2000-01-01

fibroblasts to study the effects of E5. Various endocytic markers including the pH-sensitive probe DM-NERF coupled to dextran, TransFluoSpheres and TRITC-concanavalin A, were applied. In E5-transfected cells, none of these markers colocalized with the membrane permeable probe LysoTracker Red, which...

The CD63-Syntenin-1 Complex Controls Post-Endocytic Trafficking of Oncogenic Human Papillomaviruses.

Science.gov (United States)

Gräßel, Linda; Fast, Laura Aline; Scheffer, Konstanze D; Boukhallouk, Fatima; Spoden, Gilles A; Tenzer, Stefan; Boller, Klaus; Bago, Ruzica; Rajesh, Sundaresan; Overduin, Michael; Berditchevski, Fedor; Florin, Luise

2016-08-31

Human papillomaviruses enter host cells via a clathrin-independent endocytic pathway involving tetraspanin proteins. However, post-endocytic trafficking required for virus capsid disassembly remains unclear. Here we demonstrate that the early trafficking pathway of internalised HPV particles involves tetraspanin CD63, syntenin-1 and ESCRT-associated adaptor protein ALIX. Following internalisation, viral particles are found in CD63-positive endosomes recruiting syntenin-1, a CD63-interacting adaptor protein. Electron microscopy and immunofluorescence experiments indicate that the CD63-syntenin-1 complex controls delivery of internalised viral particles to multivesicular endosomes. Accordingly, infectivity of high-risk HPV types 16, 18 and 31 as well as disassembly and post-uncoating processing of viral particles was markedly suppressed in CD63 or syntenin-1 depleted cells. Our analyses also present the syntenin-1 interacting protein ALIX as critical for HPV infection and CD63-syntenin-1-ALIX complex formation as a prerequisite for intracellular transport enabling viral capsid disassembly. Thus, our results identify the CD63-syntenin-1-ALIX complex as a key regulatory component in post-endocytic HPV trafficking.

A Comparative Study on the Alterations of Endocytic Pathways in Multiple Lysosomal Storage Disorders.

Science.gov (United States)

Rappaport, Jeff; Manthe, Rachel L; Solomon, Melani; Garnacho, Carmen; Muro, Silvia

2016-02-01

Many cellular activities and pharmaceutical interventions involve endocytosis and delivery to lysosomes for processing. Hence, lysosomal processing defects can cause cell and tissue damage, as in lysosomal storage diseases (LSDs) characterized by lysosomal accumulation of undegraded materials. This storage causes endocytic and trafficking alterations, which exacerbate disease and hinder treatment. However, there have been no systematic studies comparing different endocytic routes in LSDs. Here, we used genetic and pharmacological models of four LSDs (type A Niemann-Pick, type C Niemann-Pick, Fabry, and Gaucher diseases) and evaluated the pinocytic and receptor-mediated activity of the clathrin-, caveolae-, and macropinocytic routes. Bulk pinocytosis was diminished in all diseases, suggesting a generic endocytic alteration linked to lysosomal storage. Fluid-phase (dextran) and ligand (transferrin) uptake via the clathrin route were lower for all LSDs. Fluid-phase and ligand (cholera toxin B) uptake via the caveolar route were both affected but less acutely in Fabry or Gaucher diseases. Epidermal growth factor-induced macropinocytosis was altered in Niemann-Pick cells but not other LSDs. Intracellular trafficking of ligands was also distorted in LSD versus wild-type cells. The extent of these endocytic alterations paralleled the level of cholesterol storage in disease cell lines. Confirming this, pharmacological induction of cholesterol storage in wild-type cells disrupted endocytosis, and model therapeutics restored uptake in proportion to their efficacy in attenuating storage. This suggests a proportional and reversible relationship between endocytosis and lipid (cholesterol) storage. By analogy, the accumulation of biological material in other diseases, or foreign material from drugs or their carriers, may cause similar deficits, warranting further investigation.

Visualization of the endocytic pathway in the filamentous fungus Aspergillus oryzae using an EGFP-fused plasma membrane protein

International Nuclear Information System (INIS)

Higuchi, Yujiro; Nakahama, Tomoyuki; Shoji, Jun-ya; Arioka, Manabu; Kitamoto, Katsuhiko

2006-01-01

Endocytosis is an important process for cellular activities. However, in filamentous fungi, the existence of endocytosis has been so far elusive. In this study, we used AoUapC-EGFP, the fusion protein of a putative uric acid-xanthine permease with enhanced green fluorescent protein (EGFP) in Aspergillus oryzae, to examine whether the endocytic process occurs or not. Upon the addition of ammonium into the medium the fusion protein was internalized from the plasma membrane. The internalization of AoUapC-EGFP was completely blocked by sodium azide, cold, and cytochalasin A treatments, suggesting that the internalization possesses the general features of endocytosis. These results demonstrate the occurrence of endocytosis in filamentous fungi. Moreover, we discovered that the endosomal compartments appeared upon the induction of endocytosis and moved in a microtubule-dependent manner

Vehicle-class Specific Control of Freeway Traffic

NARCIS (Netherlands)

Schreiter, T.

2013-01-01

The increase of mobility of the past decades has led to substantial congestion on the freeways. Traffic jams emerge both on a daily basis at the same location, as well as during accidents when a part of the freeways is temporarily blocked. In those cases, traffic management centers intervene into

Megalin functions as an endocytic sonic hedgehog receptor.

Science.gov (United States)

McCarthy, Robert A; Barth, Jeremy L; Chintalapudi, Mastan R; Knaak, Christian; Argraves, W Scott

2002-07-12

Embryos deficient in the morphogen Sonic hedgehog (Shh) or the endocytic receptor megalin exhibit common neurodevelopmental abnormalities. Therefore, we have investigated the possibility that a functional relationship exists between the two proteins. During embryonic development, megalin was found to be expressed along the apical surfaces of neuroepithelial cells and was coexpressed with Shh in the ventral floor plate of the neural tube. Using enzyme-linked immunosorbent assay, homologous ligand displacement, and surface plasmon resonance techniques, it was found that the amino-terminal fragment of Shh (N-Shh) bound to megalin with high affinity. Megalin-expressing cells internalized N-Shh through a mechanism that was inhibited by antagonists of megalin, viz. anti-receptor-associated protein and anti-megalin antibodies. Heparin also inhibited N-Shh endocytosis, implicating proteoglycans in the internalization process, as has been described for other megalin ligands. Use of chloroquine to inhibit lysosomal proteinase activity showed that N-Shh endocytosed via megalin was not efficiently targeted to the lysosomes for degradation. The ability of megalin-internalized N-Shh to bypass lysosomes may relate to the finding that the interaction between N-Shh and megalin was resistant to dissociation with low pH. Together, these findings show that megalin is an efficient endocytic receptor for N-Shh. Furthermore, they implicate megalin as a new regulatory component of the Shh signaling pathway.

Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner

Directory of Open Access Journals (Sweden)

Samual C. Allgood

2017-09-01

Full Text Available The facultative intracellular bacterium Legionella pneumophila proliferates within amoebae and human alveolar macrophages, and it is the causative agent of Legionnaires' disease, a life-threatening pneumonia. Within host cells, L. pneumophila establishes a replicative haven by delivering numerous effector proteins into the host cytosol, many of which target membrane trafficking by manipulating the function of Rab GTPases. The Legionella effector AnkX is a phosphocholine transferase that covalently modifies host Rab1 and Rab35. However, a detailed understanding of the biological consequence of Rab GTPase phosphocholination remains elusive. Here, we broaden the understanding of AnkX function by presenting three lines of evidence that it interferes with host endocytic recycling. First, using immunogold transmission electron microscopy, we determined that GFP-tagged AnkX ectopically produced in mammalian cells localizes at the plasma membrane and tubular membrane compartments, sites consistent with targeting the endocytic recycling pathway. Furthermore, the C-terminal region of AnkX was responsible for association with the plasma membrane, and we determined that this region was also able to bind the phosphoinositide lipids PI(3P and PI(4P in vitro. Second, we observed that mCherry-AnkX co-localized with Rab35, a regulator of recycling endocytosis and with major histocompatibility class I protein (MHC-I, a key immunoregulatory protein whose recycling from and back to the plasma membrane is Rab35-dependent. Third, we report that during infection of macrophages, AnkX is responsible for the disruption of endocytic recycling of transferrin, and AnkX's phosphocholination activity is critical for this function. These results support the hypothesis that AnkX targets endocytic recycling during host cell infection. Finally, we have demonstrated that the phosphocholination activity of AnkX is also critical for inhibiting fusion of the Legionella

Evaluation of diversion strategies in the context of advanced traffic management systems (ATMS) for an urban traffic corridor with heterogeneous traffic

Energy Technology Data Exchange (ETDEWEB)

Korlapati, D.R.

2007-07-01

Due to urbanization and accelerated growth in vehicular traffic, most big cities in India face problems related to traffic management resulting in severe congestion, pollution, and a high rate of accidents during peak hours. Lane blocking incidents on arterials or urban traffic corridors cause major disruption to traffic flow. Peak hour congestion with low average speeds and high accident rates are commonly associated with traffic in major cities in India. The situation is deteriorating further as creation of new facilities are almost impossible, with resource and space constraints. In such scenarios, application of advanced technologies seems to offer hope. One such application area is Advanced Traffic Management Systems (ATMS), a component of intelligent transportation system (ITS). Due to the unique traffic characteristics prevailing in India, the application of such systems needs to first be evaluated before implementation. This paper proposed a research methodology for the evaluation of diversion strategies in the context of ATMS for an urban corridor in India. The evaluation framework combined several relevant modules related to various aspects of traffic control, surveillance and advisory. As part of this study, a simulation model and a simulation optimization model were developed. The simulation model was microscopic in nature and captured the driver behaviour and traffic characteristics realistically by modeling the complex interactions among vehicles traversing a corridor. It was concluded that the results and observations were useful indicators to gauge the potential success of diversion plans. 10 refs., 1 tab., 2 figs.

Estimation of Carbon Dioxide Emissions Generated by Building and Traffic in Taichung City

Directory of Open Access Journals (Sweden)

Chou-Tsang Chang

2018-01-01

Full Text Available The emissions of carbon dioxide generated by urban traffic is generally reflected by urban size. In order to discuss the traffic volume generated in developed buildings and road crossings in a single urban block, with the metropolitan area in Taichung, Taiwan as an example, this study calculates the mutual relationship between the carbon dioxide generated by the traffic volume and building development scale, in order to research energy consumption and relevance. In this research, the entire-day traffic volume of an important road crossing is subject to statistical analysis to obtain the prediction formula of total passenger car units in the main road crossing within 24 h. Then, the total CO2 emissions generated by the traffic volume in the entire year is calculated according to the investigation data of peak traffic hours within 16 blocks and the influential factors of the development scale of 95 buildings are counted. Finally, this research found that there is a passenger car unit of 4.72 generated in each square meter of land in the urban block every day, 0.99 in each square meter of floor area in the building and the average annual total CO2 emissions of each passenger car unit is 41.4 kgCO2/yr. In addition, the basic information of an integrated road system and traffic volume is used to present a readable urban traffic hot map, which can calculate a distribution map of passenger car units within one day in Taichung. This research unit can be used to forecast the development scale of various buildings in future urban blocks, in order to provide an effective approach to estimate the carbon dioxide generated by the traffic volume.

Energy Saving Scheme Based On Traffic Forwarding For Optical Fiber Access Networks

DEFF Research Database (Denmark)

Lopez, G. Arturo Rodes; Estaran Tolosa, Jose Manuel; Vegas Olmos, Juan José

2013-01-01

We report on an energy saving block that regroups and powers off OLTs during low traffic periods, resulting in energy savings up to 87,5% in the central office of optical access networks.......We report on an energy saving block that regroups and powers off OLTs during low traffic periods, resulting in energy savings up to 87,5% in the central office of optical access networks....

Urban street structure and traffic safety.

Science.gov (United States)

Mohan, Dinesh; Bangdiwala, Shrikant I; Villaveces, Andres

2017-09-01

This paper reports the influence of road type and junction density on road traffic fatality rates in U.S. cities. The Fatality Analysis Reporting System (FARS) files were used to obtain fatality rates for all cities for the years 2005-2010. A stratified random sample of 16 U.S. cities was taken, and cities with high and low road traffic fatality rates were compared on their road layout details (TIGER maps were used). Statistical analysis was done to determine the effect of junction density and road type on road traffic fatality rates. The analysis of road network and road traffic crash fatality rates in these randomly selected U.S. cities shows that, (a) higher number of junctions per road length was significantly associated with a lower motor- vehicle crash and pedestrian mortality rates, and, (b) increased number of kilometers of roads of any kind was associated with higher fatality rates, but an additional kilometer of main arterial road was associated with a significantly higher increase in total fatalities. When compared to non-arterial roads, the higher the ratio of highways and main arterial roads, there was an association with higher fatality rates. These results have important implications for road safety professionals. They suggest that once the road and street structure is put in place, that will influence whether a city has low or high traffic fatality rates. A city with higher proportion of wider roads and large city blocks will tend to have higher traffic fatality rates, and therefore in turn require much more efforts in police enforcement and other road safety measures. Urban planners need to know that smaller block size with relatively less wide roads will result in lower traffic fatality rates and this needs to be incorporated at the planning stage. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.

Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking.

Science.gov (United States)

Nowak, Matthias; Machate, Anja; Yu, Shuizi Rachel; Gupta, Mansi; Brand, Michael

2011-02-01

Forty years ago, it was proposed that during embryonic development and organogenesis, morphogen gradients provide positional information to the individual cells within a tissue leading to specific fate decisions. Recently, much insight has been gained into how such morphogen gradients are formed and maintained; however, which cellular mechanisms govern their interpretation within target tissues remains debated. Here we used in vivo fluorescence correlation spectroscopy and automated image analysis to assess the role of endocytic sorting dynamics on fibroblast growth factor 8 (Fgf8) morphogen gradient interpretation. By interfering with the function of the ubiquitin ligase Cbl, we found an expanded range of Fgf target gene expression and a delay of Fgf8 lysosomal transport. However, the extracellular Fgf8 morphogen gradient remained unchanged, indicating that the observed signalling changes are due to altered gradient interpretation. We propose that regulation of morphogen signalling activity through endocytic sorting allows fast feedback-induced changes in gradient interpretation during the establishment of complex patterns.

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

Science.gov (United States)

Zoncu, Roberto; Perera, Rushika M; Sebastian, Rafael; Nakatsu, Fubito; Chen, Hong; Balla, Tamas; Ayala, Guillermo; Toomre, Derek; De Camilli, Pietro V

2007-03-06

Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)], a phosphoinositide concentrated predominantly in the plasma membrane, binds endocytic clathrin adaptors, many of their accessory factors, and a variety of actin-regulatory proteins. Here we have used fluorescent fusion proteins and total internal reflection fluorescence microscopy to investigate the effect of acute PI(4,5)P(2) breakdown on the dynamics of endocytic clathrin-coated pit components and of the actin regulatory complex, Arp2/3. PI(4,5)P(2) breakdown was achieved by the inducible recruitment to the plasma membrane of an inositol 5-phosphatase module through the rapamycin/FRB/FKBP system or by treatment with ionomycin. PI(4,5)P(2) depletion resulted in a dramatic loss of clathrin puncta, which correlated with a massive dissociation of endocytic adaptors from the plasma membrane. Remaining clathrin spots at the cell surface had only weak fluorescence and were static over time. Dynamin and the p20 subunit of the Arp2/3 actin regulatory complex, which were concentrated at late-stage clathrin-coated pits and in lamellipodia, also dissociated from the plasma membrane, and these changes correlated with an arrest of motility at the cell edge. These findings demonstrate the critical importance of PI(4,5)P(2) in clathrin coat dynamics and Arp2/3-dependent actin regulation.

Mutational analysis of the yeast TRAPP subunit Trs20p identifies roles in endocytic recycling and sporulation.

Directory of Open Access Journals (Sweden)

Hichem Mahfouz

Full Text Available Trs20p is a subunit of the evolutionarily conserved TRAPP (TRAnsport Protein Particle complex that mediates various aspects of membrane trafficking. Three TRAPP complexes have been identified in yeast with roles in ER-to-Golgi trafficking, post-Golgi and endosomal-to-Golgi transport and in autophagy. The role of Trs20p, which is essential for viability and a component of all three complexes, and how it might function within each TRAPP complex, has not been clarified to date. To begin to address the role of Trs20p we generated different mutants by random mutagenesis but, surprisingly, no defects were observed in diverse anterograde transport pathways or general secretion in Trs20 temperature-sensitive mutants. Instead, mutation of Trs20 led to defects in endocytic recycling and a block in sporulation/meiosis. The phenotypes of different mutants appear to be separable suggesting that the mutations affect the function of Trs20 in different TRAPP complexes.

Zebrafish kidney phagocytes utilize macropinocytosis and Ca+-dependent endocytic mechanisms.

Directory of Open Access Journals (Sweden)

Claudia Hohn

Full Text Available BACKGROUND: The innate immune response constitutes the first line of defense against invading pathogens and consists of a variety of immune defense mechanisms including active endocytosis by macrophages and granulocytes. Endocytosis can be used as a reliable measure of selective and non-selective mechanisms of antigen uptake in the early phase of an immune response. Numerous assays have been developed to measure this response in a variety of mammalian and fish species. The small size of the zebrafish has prevented the large-scale collection of monocytes/macrophages and granulocytes for these endocytic assays. METHODOLOGY/PRINCIPAL FINDINGS: Pooled zebrafish kidney hematopoietic tissues were used as a source of phagocytic cells for flow-cytometry based endocytic assays. FITC-Dextran, Lucifer Yellow and FITC-Edwardsiella ictaluri were used to evaluate selective and non-selective mechanisms of uptake in zebrafish phagocytes. CONCLUSIONS/SIGNIFICANCE: Zebrafish kidney phagocytes characterized as monocytes/macrophages, neutrophils and lymphocytes utilize macropinocytosis and Ca(2+-dependant endocytosis mechanisms of antigen uptake. These cells do not appear to utilize a mannose receptor. Heat-killed Edwardsiella ictaluri induces cytoskeletal interactions for internalization in zebrafish kidney monocytes/macrophages and granulocytes. The proposed method is easy to implement and should prove especially useful in immunological, toxicological and epidemiological research.

Identifying factors affecting the safety of mid-block bicycle lanes considering mixed 2-wheeled traffic flow.

Science.gov (United States)

Bai, Lu; Chan, Ching-Yao; Liu, Pan; Xu, Chengcheng

2017-10-03

Electric bikes (e-bikes) have been one of the fastest growing trip modes in Southeast Asia over the past 2 decades. The increasing popularity of e-bikes raised some safety concerns regarding urban transport systems. The primary objective of this study was to identify whether and how the generalized linear regression model (GLM) could be used to relate cyclists' safety with various contributing factors when riding in a mid-block bike lane. The types of 2-wheeled vehicles in the study included bicycle-style electric bicycles (BSEBs), scooter-style electric bicycles (SSEBs), and regular bicycles (RBs). Traffic conflict technology was applied as a surrogate measure to evaluate the safety of 2-wheeled vehicles. The safety performance model was developed by adopting a generalized linear regression model for relating the frequency of rear-end conflicts between e-bikes and regular bikes to the operating speeds of BSEBs, SSEBs, and RBs in mid-block bike lanes. The frequency of rear-end conflicts between e-bikes and bikes increased with an increase in the operating speeds of e-bikes and the volume of e-bikes and bikes and decreased with an increase in the width of bike lanes. The large speed difference between e-bikes and bikes increased the frequency of rear-end conflicts between e-bikes and bikes in mid-block bike lanes. A 1% increase in the average operating speed of e-bikes would increase the expected number of rear-end conflicts between e-bikes and bikes by 1.48%. A 1% increase in the speed difference between e-bikes and bikes would increase the expected number of rear-end conflicts between e-bikes/bikes by 0.16%. The conflict frequency in mid-block bike lanes can be modeled using generalized linear regression models. The factors that significantly affected the frequency of rear-end conflicts included the operating speeds of e-bikes, the speed difference between e-bikes and regular bikes, the volume of e-bikes, the volume of bikes, and the width of bike lanes. The

Salmonella Disrupts Host Endocytic Trafficking by SopD2-Mediated Inhibition of Rab7

Directory of Open Access Journals (Sweden)

Vanessa M. D’Costa

2015-09-01

Full Text Available Intracellular bacterial pathogens of a diverse nature share the ability to evade host immunity by impairing trafficking of endocytic cargo to lysosomes for degradation, a process that is poorly understood. Here, we show that the Salmonella enterica type 3 secreted effector SopD2 mediates this process by binding the host regulatory GTPase Rab7 and inhibiting its nucleotide exchange. Consequently, this limits Rab7 interaction with its dynein- and kinesin-binding effectors RILP and FYCO1 and thereby disrupts host-driven regulation of microtubule motors. Our study identifies a bacterial effector capable of directly binding and thereby modulating Rab7 activity and a mechanism of endocytic trafficking disruption that may provide insight into the pathogenesis of other bacteria. Additionally, we provide a powerful tool for the study of Rab7 function, and a potential therapeutic target.

The Changeable Block Distance System Analysis

Science.gov (United States)

Lewiński, Andrzej; Toruń, Andrzej

The paper treats about efficiency analysis in Changeable Block Distance (CBD) System connected with wireless positioning and control of train. The analysis is based on modeling of typical ERTMS line and comparison with actual and future traffic. The calculations are related to assumed parameters of railway traffic corresponding to real time - table of distance Psary - Góra Włodowska from CMK line equipped in classic, ETCS Level 1 and ETCS with CBD systems.

Stochastic Modeling of the Clathrin-dependent and -independent Endocytic Pathways

Science.gov (United States)

Deng, Hua; Dutta, Prashanta; Liu, Jin

2017-11-01

Endocytosis is one of the important processes that bioparticles use to enter the cells. During endocytosis the membrane-bound vesicles are formed by the invagination of plasma membrane as a result of interactions among many proteins and cytoskeletons. The clathrin-mediated endocytosis is one of the most significant form of endocytosis, where the dynamic assembly of clathrin-coated pits play a critical role. While herpes simplex virus-1 has recently shown to infect cell by a novel phagocytosis-like endocytic pathway where actin polymerization may facilitate the viral entry. In this work, we propose a stochastic model for both clathrin-dependent and -independent endocytic pathways based on Monte Carlo simulations. The important roles of clathrin coating and actin cytoskeleton as well as the impact of other biological parameters are studied. Our preliminary results indicate that there exist an intermediate particle size and ligand density that maximize the internalization efficiency. Below a critical size or surface ligand density, it is difficult for the entry of a single particle, which means clustering may needed for more efficient internalization. We also find that lower membrane bending rigidity may help promote the bioparticle entry. Research reported in this publication was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number R01GM122081.

Interscalene block for shoulder surgery | Rukewe | Annals of African ...

African Journals Online (AJOL)

Fracture dislocation of the shoulder is a common musculoskeletal injury following road traffic accident. Peripheral nerve block has become a recognized anesthetic technique due to the rapid onset of prolonged analgesia, sufficient for both pain and surgical management. However, interscalene block for shoulder surgery ...

Deliberative Self-Organizing Traffic Lights with Elementary Cellular Automata

Directory of Open Access Journals (Sweden)

Jorge L. Zapotecatl

2017-01-01

Full Text Available Self-organizing traffic lights have shown considerable improvements compared to traditional methods in computer simulations. Self-organizing methods, however, use sophisticated sensors, increasing their cost and limiting their deployment. We propose a novel approach using simple sensors to achieve self-organizing traffic light coordination. The proposed approach involves placing a computer and a presence sensor at the beginning of each block; each such sensor detects a single vehicle. Each computer builds a virtual environment simulating vehicle movement to predict arrivals and departures at the downstream intersection. At each intersection, a computer receives information across a data network from the computers of the neighboring blocks and runs a self-organizing method to control traffic lights. Our simulations showed a superior performance for our approach compared with a traditional method (a green wave and a similar performance (close to optimal compared with a self-organizing method using sophisticated sensors but at a lower cost. Moreover, the developed sensing approach exhibited greater robustness against sensor failures.

Endocytic trafficking from the small intestinal brush border probed with FM dye

DEFF Research Database (Denmark)

Hansen, Gert H; Rasmussen, Karina; Niels-Christiansen, Lise-Lotte

2009-01-01

-linking galectins/intelectin, but little is known about the dynamic properties of this highly specialized membrane. Here, we probed the endocytic membrane trafficking from the brush border of organ cultured pig intestinal mucosal explants by use of a fixable, lipophilic FM dye. The fluorescent dye readily......, contributes to the overall permeability barrier of the gut. Key words: FM dye, small intestine, brush border, endocytosis....

Endocytic activity of Sertoli cells grown in bicameral culture chambers

International Nuclear Information System (INIS)

Dai, R.X.; Djakiew, D.; Dym, M.

1987-01-01

Immature rat Sertoli cells were cultured for 7 to 14 days on Millipore filters impregnated with a reconstituted basement membrane extract in dual-environment (bicameral) culture chambers. Electron microscopy of the cultured cells revealed the presence of rod-shaped mitochondria, Golgi apparatus, rough endoplasmic reticulum, and Sertoli-Sertoli tight junctions, typical of these cells in vivo. The endocytic activity of both the apical and basal surfaces of the Sertoli cells was examined by either adding alpha 2-macroglobulin (alpha 2-M) conjugated to 20 nm gold particles to the apical chamber or by adding 125 I labeled alpha 2-M to the basal chamber. During endocytosis from the apical surface of Sertoli cells, the alpha 2-M-gold particles were bound initially to coated pits and then internalized into coated vesicles within 5 minutes. After 10 minutes, the alpha 2-M-gold was found in multi-vesicular bodies (MVBs) and by 30 minutes it was present in the lysosomes. The proportion of alpha 2-M-gold found within endocytic cell organelles after 1 hour of uptake was used to estimate the approximate time that this ligand spent in each type of organelle. The alpha 2-M-gold was present in coated pits, coated vesicles, multivesicular bodies, and lysosomes for approximately 3, 11, 22, and 24 minutes, respectively. This indicates that the initial stages of endocytosis are rapid, whereas MVBs and lysosomes are relatively long-lived

Localization and role of MYO-1, an endocytic protein in hyphae of Neurospora crassa.

Science.gov (United States)

Lara-Rojas, Fernando; Bartnicki-García, Salomón; Mouriño-Pérez, Rosa R

2016-03-01

The subapical endocytic collar is a prominent feature of hyphae of Neurospora crassa. It comprises a dynamic collection of actin patches associated with a number of proteins required for endocytosis, namely, ARP-2/3 complex, fimbrin, coronin, etc. We presently show that MYO-1 is another key component of this endocytic collar. A myo-1 sequence was identified in the genome of N. crassa and used it to generate a strain with a myo-1-sgfp allele under the ccg1 promoter. Examination of living hyphae by confocal microscopy, revealed MYO-1-GFP located mainly as a dynamic collection of small patches arranged in collar-like fashion in the hyphal subapex. Dual tagging showed MYO-1-GFP partially colocalized with two other endocytic proteins, fimbrin and coronin. MYO-1 was also present during septum formation. By recovering a viable strain, albeit severely inhibited, after deletion of myo-1, it was possible to investigate the phenotypic consequences of the elimination of MYO-1. Deletion of myo-1 caused a severe reduction in growth rate (95%), near absence of aerial mycelium and no conidiation. A reduced uptake of the lipophilic dye FM4-64 indicated a deficiency in endocytosis in the Δmyo-1 mutant. Hyphae were produced by the Δmyo-1 mutant but their morphogenesis was severely affected; hyphal morphology was distorted displaying irregular periods of isotropic and polarized growth. The morphological alterations were accompanied, and presumably caused, by a disruption in the organization and dynamics of a myosin-deprived actin cytoskeleton that, ultimately, compromised the stability and function of the Spitzenkörper as a vesicle supply center. Copyright © 2016 Elsevier Inc. All rights reserved.

INTELLIGENT TRAFFIC-SAFETY MIRROR BY USING WIRELESS SENSOR NETWORK

Directory of Open Access Journals (Sweden)

Peter Danišovič

2014-03-01

Full Text Available This article is focused on the problematic of traffic safety, dealing with the problem of car intersections with blocked view crossing by a special wireless sensor network (WSN proposed for the traffic monitoring, concretely for vehicle’s detection at places, where it is necessary. Some ultra-low-power TI products were developed due to this reason: microcontroller MSP430F2232, 868MHz RF transceiver CC1101 and LDO voltage regulator TPS7033. The WSN consist of four network nodes supplied with the special safety lightings which serve the function of intelligent traffic safety mirror.

Smart Traffic Management Protocol Based on VANET architecture

Directory of Open Access Journals (Sweden)

Amilcare Francesco Santamaria

2014-01-01

Full Text Available Nowadays one of the hottest theme in wireless environments research is the application of the newest technologies to road safety problems and traffic management exploiting the (VANET architecture. In this work, a novel protocol that aims to achieve a better traffic management is proposed. The overal system is able to reduce traffic level inside the city exploiting inter-communication among vehicles and support infrastructures also known as (V2V and (V2I communications. We design a network protocol called (STMP that takes advantages of IEEE 802.11p standard. On each road several sensors system are placed and they are responsible of monitoring. Gathered data are spread in the network exploiting ad-hoc protocol messages. The increasing knowledge about environment conditions make possible to take preventive actions. Moreover, having a realtime monitoring of the lanes it is possible to reveal roads and city blocks congestions in a shorter time. An external entity to the (VANET is responsible to manage traffic and rearrange traffic along the lanes of the city avoiding huge traffic levels.

Photocatalytic pavement blocks. Air purification by pavement blocks. Final results of the research at BRRC

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-01

The use of materials can influence to a large extent the environmental impact of traffic and of road infrastructure. Especially in urban areas, where the risk on smog formation during hot summer days is high, the use of photocatalytic pavement blocks can reduce the air pollution significantly. A project on environmental friendly concrete pavement blocks is conducted at the Belgian Road Research Centre. The use of photocatalytic material in the surface of pavement blocks to obtain air purifying materials is investigated. In contact with light, TiO2 as photocatalyst, is able to reduce the NO and NO2 content in the air, caused by the exhaust of traffic. The efficiency is tested on pavement blocks, but the technique can as well be applied on other road elements (e.g. noise reducing walls, linear elements) or as a coating on new materials or existing structures. At the previous TRA conference in Gotenborgh, Sweden, the principle of photocatalysis was presented. In this paper, emphasis will be put on the final results of the 4-year project obtained in laboratory as well as on site at the Leien of Antwerp (10,000 m{sup 2}). The results indicate a durable efficiency towards NOx reduction, which is in favour for the diminishing of the risk on ozone formation. However, the precise translation from the laboratory towards the site is still in question. The results obtained during the project are discussed in this paper.

Photocatalytic pavement blocks. Air purification by pavement blocks. Final results of the research at BRRC

International Nuclear Information System (INIS)

2009-01-01

The use of materials can influence to a large extent the environmental impact of traffic and of road infrastructure. Especially in urban areas, where the risk on smog formation during hot summer days is high, the use of photocatalytic pavement blocks can reduce the air pollution significantly. A project on environmental friendly concrete pavement blocks is conducted at the Belgian Road Research Centre. The use of photocatalytic material in the surface of pavement blocks to obtain air purifying materials is investigated. In contact with light, TiO2 as photocatalyst, is able to reduce the NO and NO2 content in the air, caused by the exhaust of traffic. The efficiency is tested on pavement blocks, but the technique can as well be applied on other road elements (e.g. noise reducing walls, linear elements) or as a coating on new materials or existing structures. At the previous TRA conference in Gotenborgh, Sweden, the principle of photocatalysis was presented. In this paper, emphasis will be put on the final results of the 4-year project obtained in laboratory as well as on site at the Leien of Antwerp (10,000 m 2 ). The results indicate a durable efficiency towards NOx reduction, which is in favour for the diminishing of the risk on ozone formation. However, the precise translation from the laboratory towards the site is still in question. The results obtained during the project are discussed in this paper

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus

DEFF Research Database (Denmark)

Lerdrup, Mads; Bruun, Silas; Grandal, Michael Vibo

2007-01-01

inhibition of HSP90 with geldanamycin this cleavage is accompanied by proteasome-dependent endocytosis of ErbB2. However, it is unknown whether C-terminal cleavage is linked to endocytosis. To study ErbB2 cleavage and endocytic trafficking, we fused yellow fluorescent protein (YFP) and cyan fluorescent...

Reconfigurable origami sonic barriers with tunable bandgaps for traffic noise mitigation

Science.gov (United States)

Thota, M.; Wang, K. W.

2017-10-01

An origami sonic barrier composed of cylindrical inclusions attached onto an origami sheet is proposed. The idea allows for tunable sound blocking properties for application in attenuating complex traffic noise spectra. Folding of the underlying origami sheet transforms the periodicity of the inclusions between different Bravais lattices, viz. between a square and a hexagonal lattice, and such significant lattice re-configuration leads to drastic tuning of dispersion characteristics. The wave tuning capabilities are corroborated via performing theoretical and numerical investigations using a plane wave expansion method and an acoustic simulation package of COMSOL, while experiments are performed on a one-seventh scaled-down model of origami sonic barrier to demonstrate the lattice re-configuration between different Bravais lattices and the associated bandgap adaptability. Good sound blocking performance in the frequency range of traffic noise spectra combined with less efforts, required for actuating one-degree of freedom folding mechanism, makes the origami sonic barrier a potential candidate for mitigating complex traffic noise.

Diagnosis diagrams for passing signals on an automatic block signaling railway section

Science.gov (United States)

Spunei, E.; Piroi, I.; Chioncel, C. P.; Piroi, F.

2018-01-01

This work presents a diagnosis method for railway traffic security installations. More specifically, the authors present a series of diagnosis charts for passing signals on a railway block equipped with an automatic block signaling installation. These charts are based on the exploitation electric schemes, and are subsequently used to develop a diagnosis software package. The thus developed software package contributes substantially to a reduction of failure detection and remedy for these types of installation faults. The use of the software package eliminates making wrong decisions in the fault detection process, decisions that may result in longer remedy times and, sometimes, to railway traffic events.

Traffic sign recognition based on deep convolutional neural network

Science.gov (United States)

Yin, Shi-hao; Deng, Ji-cai; Zhang, Da-wei; Du, Jing-yuan

2017-11-01

Traffic sign recognition (TSR) is an important component of automated driving systems. It is a rather challenging task to design a high-performance classifier for the TSR system. In this paper, we propose a new method for TSR system based on deep convolutional neural network. In order to enhance the expression of the network, a novel structure (dubbed block-layer below) which combines network-in-network and residual connection is designed. Our network has 10 layers with parameters (block-layer seen as a single layer): the first seven are alternate convolutional layers and block-layers, and the remaining three are fully-connected layers. We train our TSR network on the German traffic sign recognition benchmark (GTSRB) dataset. To reduce overfitting, we perform data augmentation on the training images and employ a regularization method named "dropout". The activation function we employ in our network adopts scaled exponential linear units (SELUs), which can induce self-normalizing properties. To speed up the training, we use an efficient GPU to accelerate the convolutional operation. On the test dataset of GTSRB, we achieve the accuracy rate of 99.67%, exceeding the state-of-the-art results.

Raft-dependent endocytic movement and intracellular cluster formation during T cell activation triggered by concanavalin A.

Science.gov (United States)

Yabuuchi, Satomi; Endo, Satoshi; Baek, KeangOk; Hoshino, Kunihide; Tsujino, Yoshio; Vestergaard, Mun'delanji C; Takagi, Masahiro

2017-12-01

Certain food ingredients can stimulate the human immune system. A lectin, concanavalin A (ConA), from Canavalia ensiformis (jack bean) is one of the most well-known food-derived immunostimulants and mediates activation of cell-mediated immunity through T cell proliferation. Generally, T cell activation is known to be triggered by the interaction between T cells and antigen-presenting cells (APCs) via a juxtacrine (contact-dependent) signaling pathway. The mechanism has been well characterized and is referred to as formation of the immunological synapse (IS). We were interested in the mechanism behind the T cell activation by food-derived ConA which might be different from that of T cell activation by APCs. The purpose of this study was to characterize T cell activation by ConA with regard to (i) movement of raft domain, (ii) endocytic vesicular transport, (iii) the cytoskeleton (actin and microtubules), and (iv) cholesterol composition. We found that raft-dependent endocytic movement was important for T cell activation by ConA and this movement was dependent on actin, microtubules, and cholesterol. The T cell signaling mechanism triggered by ConA can be defined as endocrine signaling which is distinct from the activation process triggered by interaction between T cells and APCs by juxtacrine signaling. Therefore, we hypothesized that T cell activation by ConA includes both two-dimensional superficial raft movement on the membrane surface along actin filaments and three-dimensional endocytic movement toward the inside of the cell along microtubules. These findings are important for developing new methods for immune stimulation and cancer therapy based on the function of ConA. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

PENGEMBANGAN SISTEM PENGENDALIAN TRAFFIC DAN WEB FILTERING PADA JARINGAN INTERNET BERBASIS HOTSPOT

Directory of Open Access Journals (Sweden)

Riska Robianto

2016-12-01

Full Text Available Utilization of Internet services to the hotspot network raises particular problems in traffic control and web filtering. Linux as an operating system that is open (open source, offers a variety of internet firewall systems to assist in the management of traffic, bandwidth, web filtering and one using Smoothwall Express to Linux which can convert a personal computer (PC to the Internet firewall reliable and stable. Smoothwall allows to integrated with the add-ons extends like AdvProxy and URL Filter to improve the performance of Smoohtwall and simplify configuration of the traffic control and web filtering. The research was conducted by collecting data from various sources related, then experiment with implementing Smoohtwall by adding add-ons extends to help administrators manage and regulate the bandwidth allocation of each client, block websites (URLs that are not needed. Based on these results bandwidth management can be divided equally and can block websites (URLs that are not needed like porn sites, warez, bad word, and also the quality of the network connection updatesites more stable.

Porphyromonas gingivalis Outer Membrane Vesicles Enter Human Epithelial Cells via an Endocytic Pathway and Are Sorted to Lysosomal Compartments ▿

Science.gov (United States)

Furuta, Nobumichi; Tsuda, Kayoko; Omori, Hiroko; Yoshimori, Tamotsu; Yoshimura, Fuminobu; Amano, Atsuo

2009-01-01

Porphyromonas gingivalis, a periodontal pathogen, secretes outer membrane vesicles (MVs) that contain major virulence factors, including major fimbriae and proteases termed gingipains, although it is not confirmed whether MVs enter host cells. In this study, we analyzed the mechanisms involved in the interactions of P. gingivalis MVs with human epithelial cells. Our results showed that MVs swiftly adhered to HeLa and immortalized human gingival epithelial cells in a fimbria-dependent manner and then entered via a lipid raft-dependent endocytic pathway. The intracellular MVs were subsequently routed to early endosome antigen 1-associated compartments and then were sorted to lysosomal compartments within 90 min, suggesting that intracellular MVs were ultimately degraded by the cellular digestive machinery. However, P. gingivalis MVs remained there for over 24 h and significantly induced acidified compartment formation after being taken up by the cellular digestive machinery. In addition, MV entry was shown to be mediated by a novel pathway for transmission of bacterial products into host cells, a Rac1-regulated pinocytic pathway that is independent of caveolin, dynamin, and clathrin. Our findings indicate that P. gingivalis MVs efficiently enter host cells via an endocytic pathway and survive within the endocyte organelles for an extended period, which provides better understanding of the role of MVs in the etiology of periodontitis. PMID:19651865

Traffic

International Nuclear Information System (INIS)

Lichtblau, G.

2001-01-01

This chapter deals with passenger and freight traffic, public and private transportation, traffic related environmental impacts, future developments, traffic indicators, regional traffic planning, health costs due to road traffic related air pollution, noise pollution, measures and regulations for traffic control and fuels for traffic. In particular energy consumption, energy efficiency, pollutant emissions ( CO 2 , SO 2 , NO x , HC, CO, N 2 O, NH 3 and particulates) and environmental effects of the different types of traffic and different types of fuels are compared and studied. Legal regulations and measures for an effective traffic control are discussed. (a.n.)

Traffic dynamics around weaving section influenced by accident: Cellular automata approach

Science.gov (United States)

Kong, Lin-Peng; Li, Xin-Gang; Lam, William H. K.

2015-07-01

The weaving section, as a typical bottleneck, is one source of vehicle conflicts and an accident-prone area. Traffic accident will block lanes and the road capacity will be reduced. Several models have been established to study the dynamics around traffic bottlenecks. However, little attention has been paid to study the complex traffic dynamics influenced by the combined effects of bottleneck and accident. This paper presents a cellular automaton model to characterize accident-induced traffic behavior around the weaving section. Some effective control measures are proposed and verified for traffic management under accident condition. The total flux as a function of inflow rates, the phase diagrams, the spatial-temporal diagrams, and the density and velocity profiles are presented to analyze the impact of accident. It was shown that the proposed control measures for weaving traffic can improve the capacity of weaving section under both normal and accident conditions; the accidents occurring on median lane in the weaving section are more inclined to cause traffic jam and reduce road capacity; the capacity of weaving section will be greatly reduced when the accident happens downstream the weaving section.

Robust and Adaptive Block Tracking Method Based on Particle Filter

Directory of Open Access Journals (Sweden)

Bin Sun

2015-10-01

Full Text Available In the field of video analysis and processing, object tracking is attracting more and more attention especially in traffic management, digital surveillance and so on. However problems such as objects’ abrupt motion, occlusion and complex target structures would bring difficulties to academic study and engineering application. In this paper, a fragmentsbased tracking method using the block relationship coefficient is proposed. In this method, we use particle filter algorithm and object region is divided into blocks initially. The contribution of this method is that object features are not extracted just from a single block, the relationship between current block and its neighbor blocks are extracted to describe the variation of the block. Each block is weighted according to the block relationship coefficient when the block is voted on the most matched region in next frame. This method can make full use of the relationship between blocks. The experimental results demonstrate that our method can provide good performance in condition of occlusion and abrupt posture variation.

Vision-Based Bicycle Detection Using Multiscale Block Local Binary Pattern

Directory of Open Access Journals (Sweden)

Hongyu Hu

2014-01-01

Full Text Available Bicycle traffic has heavy proportion among all travel modes in some developing countries, which is crucial for urban traffic control and management as well as facility design. This paper proposes a real-time multiple bicycle detection algorithm based on video. At first, an effective feature called multiscale block local binary pattern (MBLBP is extracted for representing the moving object, which is a well-classified feature to distinguish between bicycles and nonbicycles; then, a cascaded bicycle classifier trained by AdaBoost algorithm is proposed, which has a good computation efficiency. Finally, the method is tested with video sequence captured from the real-world traffic scenario. The bicycles in the test scenario are successfully detected.

Endocytic pathway rapidly delivers internalized molecules to lysosomes: an analysis of vesicle trafficking, clustering and mass transfer.

Science.gov (United States)

Pangarkar, Chinmay; Dinh, Anh-Tuan; Mitragotri, Samir

2012-08-20

Lysosomes play a critical role in intracellular drug delivery. For enzyme-based therapies, they represent a potential target site whereas for nucleic acid or many protein drugs, they represent the potential degradation site. Either way, understanding the mechanisms and processes involved in routing of materials to lysosomes after cellular entry is of high interest to the field of drug delivery. Most therapeutic cargoes other than small hydrophobic molecules enter the cells through endocytosis. Endocytosed cargoes are routed to lysosomes via microtubule-based transport and are ultimately shared by various lysosomes via tethering and clustering of endocytic vesicles followed by exchange of their contents. Using a combined experimental and numerical approach, here we studied the rates of mass transfer into and among the endocytic vesicles in a model cell line, 3T3 fibroblasts. In order to understand the relationship of mass transfer with microtubular transport and vesicle clustering, we varied both properties through various pharmacological agents. At the same time, microtubular transport and vesicle clustering were modeled through diffusion-advection equations and the Smoluchowski equations, respectively. Our analysis revealed that the rate of mass transfer is optimally related to microtubular transport and clustering properties of vesicles. Further, the rate of mass transfer is highest in the innate state of the cell. Any perturbation to either microtubular transport or vesicle aggregation led to reduced mass transfer to lysosome. These results suggest that in the absence of an external intervention the endocytic pathway appears to maximize molecular delivery to lysosomes. Strategies are discussed to reduce mass transfer to lysosomes so as to extend the residence time of molecules in endosomes or late endosomes, thus potentially increasing the likelihood of their escape before disposition in the lysosomes. Copyright © 2012 Elsevier B.V. All rights reserved.

Neratinib induces ErbB2 ubiquitylation and endocytic degradation via HSP90 dissociation in breast cancer cells.

Science.gov (United States)

Zhang, Yingqiu; Zhang, Jinrui; Liu, Congcong; Du, Sha; Feng, Lu; Luan, Xuelin; Zhang, Yayun; Shi, Yulin; Wang, Taishu; Wu, Yue; Cheng, Wei; Meng, Songshu; Li, Man; Liu, Han

2016-11-28

Receptor tyrosine kinase ErbB2/HER2 is frequently observed to be overexpressed in human cancers, leading to over activation of downstream signaling modules. HER2 positive is a major type of breast cancer for which ErbB2 targeting is already proving to be an effective therapeutic strategy. Apart from antibodies against ErbB2, the small molecule tyrosine kinase inhibitor lapatinib has had successful clinical outcomes, and other inhibitors such as neratinib are currently undergoing clinical investigations. In this study we report the effects of lapatinib and neratinib on the mRNA and protein levels of the ErbB2 receptor. We provide evidence that neratinib-induced down regulation of ErbB2 occurs through ubiquitin-mediated endocytic sorting and lysosomal degradation. At the mechanistic level, neratinib treatment leads to HSP90 release from ErbB2 and its subsequent ubiquitylation and endocytic degradation. Our findings provide novel insights into the mechanism of ErbB2 inhibition by neratinib. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions.

Science.gov (United States)

Gambarte Tudela, Julian; Capmany, Anahi; Romao, Maryse; Quintero, Cristian; Miserey-Lenkei, Stephanie; Raposo, Graca; Goud, Bruno; Damiani, Maria Teresa

2015-08-15

Given their obligate intracellular lifestyle, Chlamydia trachomatis ensure that they have access to multiple host sources of essential lipids by interfering with vesicular transport. These bacteria hijack Rab6-, Rab11- and Rab14-controlled trafficking pathways to acquire sphingomyelin from the Golgi complex. Another important source of sphingolipids, phospholipids and cholesterol are multivesicular bodies (MVBs). Despite their participation in chlamydial inclusion development and bacterial replication, the molecular mechanisms mediating the interaction between MVBs and chlamydial inclusions remain unknown. In the present study, we demonstrate that Rab39a labels a subset of late endocytic vesicles - mainly MVBs - that move along microtubules. Moreover, Rab39a is actively recruited to chlamydial inclusions throughout the pathogen life cycle by a bacterial-driven process that depends on the Rab39a GTP- or GDP-binding state. Interestingly, Rab39a participates in the delivery of MVBs and host sphingolipids to maturing chlamydial inclusions, thereby promoting inclusion growth and bacterial development. Taken together, our findings indicate that Rab39a favours chlamydial replication and infectivity. This is the first report showing that a late endocytic Rab GTPase is involved in chlamydial infection development. © 2015. Published by The Company of Biologists Ltd.

Effects of traffic infrastructure and road design on safe driving

NARCIS (Netherlands)

Horst, A.R.A. van der

2014-01-01

One of the building blocks of the Dutch success in road safety is the Sustainable Safety approach. This philosophy specifies that road safety should be a design requirement in road traffic with a focus on the use of human characteristics as a starting point, considering both humans’ physical

Differential effects of BDNF and neurotrophin 4 (NT4) on endocytic sorting of TrkB receptors.

Science.gov (United States)

Proenca, Catia C; Song, Minseok; Lee, Francis S

2016-08-01

Neurotrophins are a family of growth factors playing key roles in the survival, development, and function of neurons. The neurotrophins brain-derived neurotrophic factor (BDNF) and NT4 both bind to and activate TrkB receptors, however, they mediate distinct neuronal functions. The molecular mechanism of how TrkB activation by BDNF and NT4 leads to diverse outcomes is unknown. Here, we report that BDNF and NT4 lead to differential endocytic sorting of TrkB receptors resulting in diverse biological functions in cultured cortical neurons. Fluorescent microscopy and surface biotinylation experiments showed that both neurotrophins stimulate internalization of TrkB with similar kinetics. Exposure to BDNF for 2-3 h reduced the surface pool of TrkB receptors to half, whereas a longer treatment (4-5 h) with NT4 was necessary to achieve a similar level of down-regulation. Although BDNF and NT4 induced TrkB phosphorylation with similar intensities, BDNF induced more rapid ubiquitination and degradation of TrkB than NT4. Interestingly, TrkB receptor ubiquitination by these ligands have substantially different pH sensitivities, resulting in varying degrees of receptor ubiquitination at lower pH levels. Consequently, NT4 was capable of maintaining longer sustained downstream signaling activation that correlated with reduced TrkB ubiquitination at endosomal pH. Thus, by leading to altered endocytic trafficking itineraries for TrkB receptors, BDNF and NT4 elicit differential TrkB signaling in terms of duration, intensity, and specificity, which may contribute to their functional differences in vivo. The neurotrophins, brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4), both bind to and activate TrkB receptors, however, they mediate distinct neuronal functions. Here, we propose that BDNF and NT4 lead to differential endocytic sorting of TrkB receptors resulting in diverse biological functions. BDNF induces more rapid ubiquitination and degradation of TrkB than NT4

An antibody toolkit for the study of membrane traffic in Drosophila melanogaster

Directory of Open Access Journals (Sweden)

Falko Riedel

2016-07-01

Full Text Available The use of Drosophila melanogaster as a model organism has been pivotal to understanding the developmental processes of metazoans. However, the use of flies for studying subcellular organization is hampered by a paucity of reliable reagents to label specific organelles. Here, we describe the generation of mouse monoclonal antibodies against a set of markers of the secretory and endocytic pathways, along with goat polyclonal antibodies against two Golgi proteins. We show that the monoclonal antibodies are highly specific and sufficiently sensitive to detect endogenous proteins in crude extracts by immunoblotting with little background staining. By immunofluorescence the major compartments of the membrane traffic system (including the endoplasmic reticulum, the Golgi, and early and late endosomes are labeled by at least one antibody. Moreover, the antibodies can be used to label organelles in fly tissues including salivary glands and wing imaginal discs. We anticipate that these antibodies will provide a useful tool kit to facilitate the investigation of how the endomembrane system functions and varies in the diverse tissue types of metazoans.

Quantitative analysis of pedestrian safety at uncontrolled multi-lane mid-block crosswalks in China.

Science.gov (United States)

Zhang, Cunbao; Zhou, Bin; Chen, Guojun; Chen, Feng

2017-11-01

A lot of pedestrian-vehicle crashes at mid-block crosswalks severely threaten pedestrian's safety around the world. The situations are even worse in China due to low yielding rate of vehicles at crosswalks. In order to quantitatively analyze pedestrian's safety at multi-lane mid-block crosswalks, the number of pedestrian-vehicle conflicts was utilized to evaluate pedestrian's accident risk. Five mid-block crosswalks (Wuhan, China) were videoed to collect data of traffic situation and pedestrian-vehicle conflicts, and the quantity and spatial distribution of pedestrian-vehicle conflicts at multi-lane mid-block crosswalk were analyzed according to lane-based post-encroachment time(LPET). Statistical results indicate that conflicts are mainly concentrated in lane3 and lane6. Percentage of conflict of each lane numbered from 1 to 6 respectively are 4.1%, 13.1%, 19.8%, 8.4%, 19.0%, 28.1%. Conflict rate under different crossing strategies are also counted. Moreover, an order probit (OP) model of pedestrian-vehicle conflict analysis (PVCA) was built to find out the contributions corresponding to those factors (such as traffic volume, vehicle speed, pedestrian crossing behavior, pedestrian refuge, etc.) to pedestrian-vehicle conflicts. The results show that: pedestrian refuge have positive effects on pedestrian safety; on the other hand, high vehicle speed, high traffic volume, rolling gap crossing pattern, and larger pedestrian platoon have negative effects on pedestrian safety. Based on our field observation and PVCA model, the number of conflicts will rise by 2% while the traffic volume increases 200 pcu/h; similarly, if the vehicle speed increases 5km/h, the number of conflicts will rise by 12% accordingly. The research results could be used to evaluate pedestrian safety at multi-lane mid-block crosswalks, and useful to improve pedestrian safety by means of pedestrian safety education, pedestrian refuge setting, vehicle speed limiting, and so on. Copyright © 2017

Relation between Observed and Perceived Traffic Noise and Socio-Economic Status in Urban Blocks of Different Characteristics

Directory of Open Access Journals (Sweden)

Malte von Szombathely

2018-02-01

Full Text Available Living in cities offers many benefits and thus more and more people are living in urban areas. However, the concentration of human activities also creates environmental stressors with severe influence on people’s health and well-being. Noise is an environmental stressor with known health impact. Despite this, studies investigating small-scale difference in noise exposure and annoyance are lacking. Against this background, this case study investigates environmental justice empirically, focusing on the distribution of road traffic noise and its perception in Hamburg, Germany. The study outlines a methodological approach that takes into account subjective and objective measures of exposure in small-scale residential blocks. The results show that annoyance by noise is clearly related to noise emission. Moreover, different groups are affected by noise pollution in our study area unequally. In particular, younger people and people with lower socio-economic status have higher probabilities to be affected by noise. Additionally, it emerged that participants reporting higher levels of annoyance from noise are on average younger than those feeling less annoyed. Overall, these results show that the current legal noise limits applicable to residential planning processes in German cities are not sufficient to prevent substantial annoyance effects in residential populations.

The Endocytic Recycling Regulatory Protein EHD1 Is Required for Ocular Lens Development

Science.gov (United States)

Arya, Priyanka; Rainey, Mark A.; Bhattacharyya, Sohinee; Mohapatra, Bhopal; George, Manju; Kuracha, Murali R; Storck, Matthew D.; Band, Vimla; Govindarajan, Venkatesh; Band, Hamid

2015-01-01

The C-terminal Eps15 homology domain-containing (EHD) proteins play a key role in endocytic recycling, a fundamental cellular process that ensures the return of endocytosed membrane components and receptors back to the cell surface. To define the in vivo biological functions of EHD1, we have generated Ehd1 knockout mice and previously reported a requirement of EHD1 for spermatogenesis. Here, we show that approximately 56% of the Ehd1-null mice displayed gross ocular abnormalities, including anophthalmia, aphakia, microphthalmia and congenital cataracts. Histological characterization of ocular abnormalities showed pleiotropic defects that include a smaller or absent lens, persistence of lens stalk and hyaloid vasculature, and deformed optic cups. To test whether these profound ocular defects resulted from the loss of EHD1 in the lens or in non-lenticular tissues, we deleted the Ehd1 gene selectively in the presumptive lens ectoderm using Le-Cre. Conditional Ehd1 deletion in the lens resulted in developmental defects that included thin epithelial layers, small lenses and absence of corneal endothelium. Ehd1 deletion in the lens also resulted in reduced lens epithelial proliferation, survival and expression of junctional proteins E-cadherin and ZO-1. Finally, Le-Cre-mediated deletion of Ehd1 in the lens led to defects in corneal endothelial differentiation. Taken together, these data reveal a unique role for EHD1 in early lens development and suggest a previously unknown link between the endocytic recycling pathway and regulation of key developmental processes including proliferation, differentiation and morphogenesis. PMID:26455409

Ventilation and Air Quality in City Blocks Using Large-Eddy Simulation—Urban Planning Perspective

Directory of Open Access Journals (Sweden)

Mona Kurppa

2018-02-01

Full Text Available Buildings and vegetation alter the wind and pollutant transport in urban environments. This comparative study investigates the role of orientation and shape of perimeter blocks on the dispersion and ventilation of traffic-related air pollutants, and the street-level concentrations along a planned city boulevard. A large-eddy simulation (LES model PALM is employed over a highly detailed representation of the urban domain including street trees and forested areas. Air pollutants are represented by massless and passive particles (non-reactive gases, which are released with traffic-related emission rates. High-resolution simulations for four different city-block-structures are conducted over a 8.2 km 2 domain under two contrasting inflow conditions with neutral and stable atmospheric stratification corresponding the general and wintry meteorological conditions. Variation in building height together with multiple cross streets along the boulevard improves ventilation, resulting in 7–9% lower mean concentrations at pedestrian level. The impact of smaller scale variability in building shape was negligible. Street trees further complicate the flow and dispersion. Notwithstanding the surface roughness, atmospheric stability controls the concentration levels with higher values under stably stratified inflow. Little traffic emissions are transported to courtyards. The results provide urban planners direct information to reduce air pollution by proper structural layout of perimeter blocks.

A Survey on Urban Traffic Management System Using Wireless Sensor Networks

Science.gov (United States)

Nellore, Kapileswar; Hancke, Gerhard P.

2016-01-01

Nowadays, the number of vehicles has increased exponentially, but the bedrock capacities of roads and transportation systems have not developed in an equivalent way to efficiently cope with the number of vehicles traveling on them. Due to this, road jamming and traffic correlated pollution have increased with the associated adverse societal and financial effect on different markets worldwide. A static control system may block emergency vehicles due to traffic jams. Wireless Sensor networks (WSNs) have gained increasing attention in traffic detection and avoiding road congestion. WSNs are very trendy due to their faster transfer of information, easy installation, less maintenance, compactness and for being less expensive compared to other network options. There has been significant research on Traffic Management Systems using WSNs to avoid congestion, ensure priority for emergency vehicles and cut the Average Waiting Time (AWT) of vehicles at intersections. In recent decades, researchers have started to monitor real-time traffic using WSNs, RFIDs, ZigBee, VANETs, Bluetooth devices, cameras and infrared signals. This paper presents a survey of current urban traffic management schemes for priority-based signalling, and reducing congestion and the AWT of vehicles. The main objective of this survey is to provide a taxonomy of different traffic management schemes used for avoiding congestion. Existing urban traffic management schemes for the avoidance of congestion and providing priority to emergency vehicles are considered and set the foundation for further research. PMID:26828489

Evaluation of daily time spent in transportation and traffic-influenced microenvironments by urban Canadians.

Science.gov (United States)

Matz, Carlyn J; Stieb, David M; Egyed, Marika; Brion, Orly; Johnson, Markey

2018-01-01

Exposure to traffic and traffic-related air pollution is associated with a wide array of health effects. Time spent in a vehicle, in active transportation, along roadsides, and in close proximity to traffic can substantially contribute to daily exposure to air pollutants. For this study, we evaluated daily time spent in transportation and traffic-influenced microenvironments by urban Canadians using the Canadian Human Activity Pattern Survey (CHAPS) 2 results. Approximately 4-7% of daily time was spent in on- or near-road locations, mainly associated with being in a vehicle and smaller contributions from active transportation. Indoor microenvironments can be impacted by traffic emissions, especially when located near major roadways. Over 60% of the target population reported living within one block of a roadway with moderate to heavy traffic, which was variable with income level and city, and confirmed based on elevated NO 2 exposure estimated using land use regression. Furthermore, over 55% of the target population ≤ 18 years reported attending a school or daycare in close proximity to moderate to heavy traffic, and little variation was observed based on income or city. The results underline the importance of traffic emissions as a major source of exposure in Canadian urban centers, given the time spent in traffic-influenced microenvironments.

Trip-timing decisions with traffic incidents

DEFF Research Database (Denmark)

Fosgerau, Mogens; Lindsey, Robin

2013-01-01

This paper analyzes traffic bottleneck congestion when drivers randomly cause incidents that temporarily block the bottleneck. Drivers have general scheduling preferences for time spent at home and at work. They independently choose morning departure times from home to maximize expected utility...... without knowing whether an incident has occurred. The resulting departure time pattern may be compressed or dispersed according to whether or not the bottleneck is fully utilized throughout the departure period on days without incidents. For both the user equilibrium (UE) and the social optimum (SO...

Traffic theory

National Research Council Canada - National Science Library

Gazis, Denos C

2002-01-01

... of traffic signal settings The vehicle-actuated traffic signal 87 89 77 CHAPTER 3. TRAFFIC CONTROL 101 Objectives of Traffic Control 103 Single, Isolated Intersection 105 Synchronization Scheme...

Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells.

Science.gov (United States)

Linford, Andrea; Yoshimura, Shin-ichiro; Nunes Bastos, Ricardo; Langemeyer, Lars; Gerondopoulos, Andreas; Rigden, Daniel J; Barr, Francis A

2012-05-15

Rab GTPases define the vesicle trafficking pathways underpinning cell polarization and migration. Here, we find that Rab4, Rab11, and Rab14 and the candidate Rab GDP-GTP exchange factors (GEFs) FAM116A and AVL9 are required for cell migration. Rab14 and its GEF FAM116A localize to and act on an intermediate compartment of the transferrin-recycling pathway prior to Rab11 and after Rab5 and Rab4. This Rab14 intermediate recycling compartment has specific functions in migrating cells discrete from early and recycling endosomes. Rab14-depleted cells show increased N-cadherin levels at junctional complexes and cannot resolve cell-cell junctions. This is due to decreased shedding of cell-surface N-cadherin by the ADAM family protease ADAM10/Kuzbanian. In FAM116A- and Rab14-depleted cells, ADAM10 accumulates in a transferrin-positive endocytic compartment, and the cell-surface level of ADAM10 is correspondingly reduced. FAM116 and Rab14 therefore define an endocytic recycling pathway needed for ADAM protease trafficking and regulation of cell-cell junctions. Copyright © 2012 Elsevier Inc. All rights reserved.

A sensemaking perspective on framing the mental picture of air traffic controllers.

Science.gov (United States)

Malakis, Stathis; Kontogiannis, Tom

2013-03-01

It has long been recognized that controller strategies are based on a 'mental picture' or representation of traffic situations. Earlier studies indicated that controllers tend to maintain a selective representation of traffic flows based on a few salient traffic features that point out to interesting events (e.g., potential conflicts). A field study is presented in this paper that examines salient features or 'knowledge variables' that constitute the building blocks of controller mental pictures. Verbal reports from participants, a field experiment and observations of real-life scenarios provided insights into the cognitive processes that shape and reframe the mental pictures of controllers. Several cognitive processes (i.e., problem detection, elaboration, reframing and replanning) have been explored within a particular framework of sensemaking stemming from the data/frame theory (Klein et al., 2007). Cognitive maps, representing standard and non-standard air traffic flows, emerged as an explanatory framework for making sense of traffic patterns and for reframing mental pictures. The data/frame theory proved to be a useful theoretical tool for investigating complex cognitive phenomena. The findings of the study have implications for the design of training curricula and decision support systems in air traffic control systems. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Blocking-resistant communication through domain fronting

Directory of Open Access Journals (Sweden)

Fifield David

2015-06-01

Full Text Available We describe “domain fronting,” a versatile censorship circumvention technique that hides the remote endpoint of a communication. Domain fronting works at the application layer, using HTTPS, to communicate with a forbidden host while appearing to communicate with some other host, permitted by the censor. The key idea is the use of different domain names at different layers of communication. One domain appears on the “outside” of an HTTPS request—in the DNS request and TLS Server Name Indication—while another domain appears on the “inside”—in the HTTP Host header, invisible to the censor under HTTPS encryption. A censor, unable to distinguish fronted and nonfronted traffic to a domain, must choose between allowing circumvention traffic and blocking the domain entirely, which results in expensive collateral damage. Domain fronting is easy to deploy and use and does not require special cooperation by network intermediaries. We identify a number of hard-to-block web services, such as content delivery networks, that support domain-fronted connections and are useful for censorship circumvention. Domain fronting, in various forms, is now a circumvention workhorse. We describe several months of deployment experience in the Tor, Lantern, and Psiphon circumvention systems, whose domain-fronting transports now connect thousands of users daily and transfer many terabytes per month.

Modeling secondary accidents identified by traffic shock waves.

Science.gov (United States)

Junhua, Wang; Boya, Liu; Lanfang, Zhang; Ragland, David R

2016-02-01

The high potential for occurrence and the negative consequences of secondary accidents make them an issue of great concern affecting freeway safety. Using accident records from a three-year period together with California interstate freeway loop data, a dynamic method for more accurate classification based on the traffic shock wave detecting method was used to identify secondary accidents. Spatio-temporal gaps between the primary and secondary accident were proven be fit via a mixture of Weibull and normal distribution. A logistic regression model was developed to investigate major factors contributing to secondary accident occurrence. Traffic shock wave speed and volume at the occurrence of a primary accident were explicitly considered in the model, as a secondary accident is defined as an accident that occurs within the spatio-temporal impact scope of the primary accident. Results show that the shock waves originating in the wake of a primary accident have a more significant impact on the likelihood of a secondary accident occurrence than the effects of traffic volume. Primary accidents with long durations can significantly increase the possibility of secondary accidents. Unsafe speed and weather are other factors contributing to secondary crash occurrence. It is strongly suggested that when police or rescue personnel arrive at the scene of an accident, they should not suddenly block, decrease, or unblock the traffic flow, but instead endeavor to control traffic in a smooth and controlled manner. Also it is important to reduce accident processing time to reduce the risk of secondary accident. Copyright © 2015 Elsevier Ltd. All rights reserved.

Altered TGF-β endocytic trafficking contributes to the increased signaling in Marfan syndrome.

Science.gov (United States)

Siegert, Anna-Maria; Serra-Peinado, Carla; Gutiérrez-Martínez, Enric; Rodríguez-Pascual, Fernando; Fabregat, Isabel; Egea, Gustavo

2018-02-01

The main cardiovascular alteration in Marfan syndrome (MFS) is the formation of aortic aneurysms in which augmented TGF-β signaling is reported. However, the primary role of TGF-β signaling as a molecular link between the genetic mutation of fibrillin-1 and disease onset is controversial. The compartmentalization of TGF-β endocytic trafficking has been shown to determine a signaling response in which clathrin-dependent internalization leads to TGF-β signal propagation, and caveolin-1 (CAV-1) associated internalization leads to signal abrogation. We here studied the contribution of endocytic trafficking compartmentalization to increased TGF-β signaling in vascular smooth muscle cells (VSMC) from MFS patients. We examined molecular components involved in clathrin- (SARA, SMAD2) and caveolin-1- (SMAD7, SMURF2) dependent endocytosis. Marfan VSMC showed higher recruitment of SARA and SMAD2 to membranes and their increased interaction with TGF-β receptor II, as well as higher colocalization of SARA with the early endosome marker EEA1. We assessed TGF-β internalization using a biotinylated ligand (b-TGF-β), which colocalized equally with either EEA1 or CAV-1 in VSMC from Marfan patients and controls. However, in Marfan cells, colocalization of b-TGF-β with SARA and EEA1 was increased and accompanied by decreased colocalization with CAV-1 at EEA1-positive endosomes. Moreover, Marfan VSMC showed higher transcriptional levels and membrane enrichment of RAB5. Our results indicate that increased RAB5-associated SARA localization to early endosomes facilitates its TGF-β receptor binding and phosphorylation of signaling mediator SMAD2 in Marfan VSMC. This is accompanied by a reduction of TGF-β sorting into multifunctional vesicles containing cargo from both internalization pathways. Copyright © 2017 Elsevier B.V. All rights reserved.

An auxiliary graph based dynamic traffic grooming algorithm in spatial division multiplexing enabled elastic optical networks with multi-core fibers

Science.gov (United States)

Zhao, Yongli; Tian, Rui; Yu, Xiaosong; Zhang, Jiawei; Zhang, Jie

2017-03-01

A proper traffic grooming strategy in dynamic optical networks can improve the utilization of bandwidth resources. An auxiliary graph (AG) is designed to solve the traffic grooming problem under a dynamic traffic scenario in spatial division multiplexing enabled elastic optical networks (SDM-EON) with multi-core fibers. Five traffic grooming policies achieved by adjusting the edge weights of an AG are proposed and evaluated through simulation: maximal electrical grooming (MEG), maximal optical grooming (MOG), maximal SDM grooming (MSG), minimize virtual hops (MVH), and minimize physical hops (MPH). Numeric results show that each traffic grooming policy has its own features. Among different traffic grooming policies, an MPH policy can achieve the lowest bandwidth blocking ratio, MEG can save the most transponders, and MSG can obtain the fewest cores for each request.

Spatial resolution requirements for traffic-related air pollutant exposure evaluations

Science.gov (United States)

Batterman, Stuart; Chambliss, Sarah; Isakov, Vlad

2014-09-01

Vehicle emissions represent one of the most important air pollution sources in most urban areas, and elevated concentrations of pollutants found near major roads have been associated with many adverse health impacts. To understand these impacts, exposure estimates should reflect the spatial and temporal patterns observed for traffic-related air pollutants. This paper evaluates the spatial resolution and zonal systems required to estimate accurately intraurban and near-road exposures of traffic-related air pollutants. The analyses use the detailed information assembled for a large (800 km2) area centered on Detroit, Michigan, USA. Concentrations of nitrogen oxides (NOx) due to vehicle emissions were estimated using hourly traffic volumes and speeds on 9700 links representing all but minor roads in the city, the MOVES2010 emission model, the RLINE dispersion model, local meteorological data, a temporal resolution of 1 h, and spatial resolution as low as 10 m. Model estimates were joined with the corresponding shape files to estimate residential exposures for 700,000 individuals at property parcel, census block, census tract, and ZIP code levels. We evaluate joining methods, the spatial resolution needed to meet specific error criteria, and the extent of exposure misclassification. To portray traffic-related air pollutant exposure, raster or inverse distance-weighted interpolations are superior to nearest neighbor approaches, and interpolations between receptors and points of interest should not exceed about 40 m near major roads, and 100 m at larger distances. For census tracts and ZIP codes, average exposures are overestimated since few individuals live very near major roads, the range of concentrations is compressed, most exposures are misclassified, and high concentrations near roads are entirely omitted. While smaller zones improve performance considerably, even block-level data can misclassify many individuals. To estimate exposures and impacts of traffic

A Numerical Simulation of Traffic-Related Air Pollution Exposures in Urban Street Canyons

Science.gov (United States)

Liu, J.; Fu, X.; Tao, S.

2016-12-01

Urban street canyons are usually associated with intensive vehicle emissions. However, the high buildings successively along both sides of a street block the dispersion of traffic-generated air pollutants, which enhances human exposure and adversely affects human health. In this study, an urban scale traffic pollution dispersion model is developed with the consideration of street distribution, canyon geometry, background meteorology, traffic assignment, traffic emissions and air pollutant dispersion. Vehicle exhausts generated from traffic flows will first disperse inside a street canyon along the micro-scale wind field (generated by computational fluid dynamics (CFD) model) and then leave the street canyon and further disperse over the urban area. On the basis of this model, the effects of canyon geometry on the distribution of NOx and CO from traffic emissions were studied over the center of Beijing, China. We found that an increase of building height along the streets leads to higher pollution levels inside streets and lower pollution levels outside, resulting in higher domain-averaged concentrations over the area. In addition, street canyons with equal (or highly uneven) building heights on two sides of a street tend to lower the urban-scale air pollution concentrations at pedestrian level. Our results indicate that canyon geometry strongly influences human exposure to traffic pollutants in the populated urban area. Carefully planning street layout and canyon geometry in consideration of traffic demand as well as local weather pattern may significantly reduce the chances of unhealthy air being inhaled by urban residents.

Real-Time Corrected Traffic Correlation Model for Traffic Flow Forecasting

Directory of Open Access Journals (Sweden)

Hua-pu Lu

2015-01-01

Full Text Available This paper focuses on the problems of short-term traffic flow forecasting. The main goal is to put forward traffic correlation model and real-time correction algorithm for traffic flow forecasting. Traffic correlation model is established based on the temporal-spatial-historical correlation characteristic of traffic big data. In order to simplify the traffic correlation model, this paper presents correction coefficients optimization algorithm. Considering multistate characteristic of traffic big data, a dynamic part is added to traffic correlation model. Real-time correction algorithm based on Fuzzy Neural Network is presented to overcome the nonlinear mapping problems. A case study based on a real-world road network in Beijing, China, is implemented to test the efficiency and applicability of the proposed modeling methods.

Subversion of the Endocytic and Secretory Pathways by Bacterial Effector Proteins

Directory of Open Access Journals (Sweden)

Mary M. Weber

2018-01-01

Full Text Available Intracellular bacteria have developed numerous strategies to hijack host vesicular trafficking pathways to form their unique replicative niches. To promote intracellular replication, the bacteria must interact with host organelles and modulate host signaling pathways to acquire nutrients and membrane for the growing parasitophorous vacuole all while suppressing activation of the immune response. To facilitate host cell subversion, bacterial pathogens use specialized secretion systems to deliver bacterial virulence factors, termed effectors, into the host cell that mimic, agonize, and/or antagonize the function of host proteins. In this review we will discuss how bacterial effector proteins from Coxiella burnetii, Brucella abortus, Salmonella enterica serovar Typhimurium, Legionella pneumophila, Chlamydia trachomatis, and Orientia tsutsugamushi manipulate the endocytic and secretory pathways. Understanding how bacterial effector proteins manipulate host processes not only gives us keen insight into bacterial pathogenesis, but also enhances our understanding of how eukaryotic membrane trafficking is regulated.

Impact of traffic noise on railway traffic safety

Directory of Open Access Journals (Sweden)

Zdravko TOŠ

2008-01-01

Full Text Available Traffic noise is one of the dominant factors of ergo-assessment. The harmful impact of traffic noise on the engine driver as target group can be studied in isolation from other ergo-assessment factors only in the initial phase of research. The simultaneous action of several related factors in the system of ergo-assessment factors has cumulative effect on the perception and psychomotoric status of the railway traffic participants in the appropriate traffic situation. The initial partial research of traffic noise by a combination of several scientific methods needs to be eventually upgraded by studying the relations among several concurrent important or dominant ergo-assessment factors.

Vps1 in the late endosome-to-vacuole traffic

Indian Academy of Sciences (India)

2013-01-13

Jan 13, 2013 ... the plasma membrane lipids and follows the endocytic inter- nalization pathways ... plasm and found also as punctuate structures (figure 1A). Our explanation ..... 1992 Morphological classification of the yeast vacuolar protein.

Symmetry breaking in optimal timing of traffic signals on an idealized two-way street.

Science.gov (United States)

Panaggio, Mark J; Ottino-Löffler, Bertand J; Hu, Peiguang; Abrams, Daniel M

2013-09-01

Simple physical models based on fluid mechanics have long been used to understand the flow of vehicular traffic on freeways; analytically tractable models of flow on an urban grid, however, have not been as extensively explored. In an ideal world, traffic signals would be timed such that consecutive lights turned green just as vehicles arrived, eliminating the need to stop at each block. Unfortunately, this "green-wave" scenario is generally unworkable due to frustration imposed by competing demands of traffic moving in different directions. Until now this has typically been resolved by numerical simulation and optimization. Here, we develop a theory for the flow in an idealized system consisting of a long two-way road with periodic intersections. We show that optimal signal timing can be understood analytically and that there are counterintuitive asymmetric solutions to this signal coordination problem. We further explore how these theoretical solutions degrade as traffic conditions vary and automotive density increases.

Symmetry breaking in optimal timing of traffic signals on an idealized two-way street

Science.gov (United States)

Panaggio, Mark J.; Ottino-Löffler, Bertand J.; Hu, Peiguang; Abrams, Daniel M.

2013-09-01

Simple physical models based on fluid mechanics have long been used to understand the flow of vehicular traffic on freeways; analytically tractable models of flow on an urban grid, however, have not been as extensively explored. In an ideal world, traffic signals would be timed such that consecutive lights turned green just as vehicles arrived, eliminating the need to stop at each block. Unfortunately, this “green-wave” scenario is generally unworkable due to frustration imposed by competing demands of traffic moving in different directions. Until now this has typically been resolved by numerical simulation and optimization. Here, we develop a theory for the flow in an idealized system consisting of a long two-way road with periodic intersections. We show that optimal signal timing can be understood analytically and that there are counterintuitive asymmetric solutions to this signal coordination problem. We further explore how these theoretical solutions degrade as traffic conditions vary and automotive density increases.

Automation of Data Traffic Control on DSM Architecture

Science.gov (United States)

Frumkin, Michael; Jin, Hao-Qiang; Yan, Jerry

2001-01-01

The design of distributed shared memory (DSM) computers liberates users from the duty to distribute data across processors and allows for the incremental development of parallel programs using, for example, OpenMP or Java threads. DSM architecture greatly simplifies the development of parallel programs having good performance on a few processors. However, to achieve a good program scalability on DSM computers requires that the user understand data flow in the application and use various techniques to avoid data traffic congestions. In this paper we discuss a number of such techniques, including data blocking, data placement, data transposition and page size control and evaluate their efficiency on the NAS (NASA Advanced Supercomputing) Parallel Benchmarks. We also present a tool which automates the detection of constructs causing data congestions in Fortran array oriented codes and advises the user on code transformations for improving data traffic in the application.

TRAFFIC SIMULATION FOR MIXED TRAFFIC SYSTEMS

African Journals Online (AJOL)

EGETE

2012-05-04

May 4, 2012 ... Traffic problem is classified into single and mixed, especially in most developing countries, where motorbikes are ..... The traffic light control system presented by its location on ... multi-destination dynamic routing and real-time.

Stem-cell-specific endocytic degradation defects lead to intestinal dysplasia in Drosophila

Directory of Open Access Journals (Sweden)

Péter Nagy

2016-05-01

Full Text Available UV radiation resistance-associated gene (UVRAG is a tumor suppressor involved in autophagy, endocytosis and DNA damage repair, but how its loss contributes to colorectal cancer is poorly understood. Here, we show that UVRAG deficiency in Drosophila intestinal stem cells leads to uncontrolled proliferation and impaired differentiation without preventing autophagy. As a result, affected animals suffer from gut dysfunction and short lifespan. Dysplasia upon loss of UVRAG is characterized by the accumulation of endocytosed ligands and sustained activation of STAT and JNK signaling, and attenuation of these pathways suppresses stem cell hyperproliferation. Importantly, the inhibition of early (dynamin-dependent or late (Rab7-dependent steps of endocytosis in intestinal stem cells also induces hyperproliferation and dysplasia. Our data raise the possibility that endocytic, but not autophagic, defects contribute to UVRAG-deficient colorectal cancer development in humans.

Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin

DEFF Research Database (Denmark)

Gburek, Jakub; Verroust, Pierre J; Willnow, Thomas E

2002-01-01

-Sepharose affinity chromatography of solubilized renal brush-border membranes. Apparent dissociation constants of 1.7 microM for megalin and 4.1 microM for cubilin were determined by surface plasmon resonance analysis. The binding was calcium dependent in both cases. Uptake of fluorescence-labeled hemoglobin by BN......The kidney is the main site of hemoglobin clearance and degradation in conditions of severe hemolysis. Herein it is reported that megalin and cubilin, two epithelial endocytic receptors, mediate the uptake of hemoglobin in renal proximal tubules. Both receptors were purified by use of hemoglobin...... not affect the uptake. By use of immunohistochemistry, it was demonstrated that uptake of hemoglobin in proximal tubules of rat, mouse, and dog kidneys occurs under physiologic conditions. Studies on normal and megalin knockout mouse kidney sections showed that megalin is responsible for physiologic...

An enhanced model for minimizing fuel consumption under block-queuing in a drive-through service system

Energy Technology Data Exchange (ETDEWEB)

Reilly, C.H.; Berglin, J. [University of Central Florida, Orlando, FL (United States). Dept. of Industrial Engineering and Management Systems

2004-05-01

We present a new model for determining the optimal block-size under block-queuing in a simple, single-channel queue at a drive-through service facility. With block-queuing, a queue is partitioned into an active section and a passive section, where drivers are asked to turn off their engines until the active section clears. Our model prescribes a block-size, i.e., a maximum number of vehicles in the active section, which minimizes the expected amount of fuel consumed in the queue. It can assess the effects of the traffic intensity, the service-time variance, and the proportion of compliant drivers in the passive section on the optimal block- size and on fuel consumption in the queue. (author)

Traffic signal synchronization.

Science.gov (United States)

Huang, Ding-wei; Huang, Wei-neng

2003-05-01

The benefits of traffic signal synchronization are examined within the cellular automata approach. The microsimulations of traffic flow are obtained with different settings of signal period T and time delay delta. Both numerical results and analytical approximations are presented. For undersaturated traffic, the green-light wave solutions can be realized. For saturated traffic, the correlation among the traffic signals has no effect on the throughput. For oversaturated traffic, the benefits of synchronization are manifest only when stochastic noise is suppressed.

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

DEFF Research Database (Denmark)

Madsen, Daniel H; Jürgensen, Henrik J; Ingvarsen, Signe

2013-01-01

A well-coordinated remodeling of uncalcified collagen matrices is a pre-requisite for bone development and homeostasis. Collagen turnover proceeds through different pathways, either involving extracellular reactions exclusively, or being dependent on endocytic processes. Extracellular collagen...... degradation requires the action of secreted or membrane attached collagenolytic proteases, whereas the alternative collagen degradation pathway proceeds intracellularly after receptor-mediated uptake and delivery to the lysosomes. In this study we have examined the functional interplay between...

Traffic sharing algorithms for hybrid mobile networks

Science.gov (United States)

Arcand, S.; Murthy, K. M. S.; Hafez, R.

1995-01-01

In a hybrid (terrestrial + satellite) mobile personal communications networks environment, a large size satellite footprint (supercell) overlays on a large number of smaller size, contiguous terrestrial cells. We assume that the users have either a terrestrial only single mode terminal (SMT) or a terrestrial/satellite dual mode terminal (DMT) and the ratio of DMT to the total terminals is defined gamma. It is assumed that the call assignments to and handovers between terrestrial cells and satellite supercells take place in a dynamic fashion when necessary. The objectives of this paper are twofold, (1) to propose and define a class of traffic sharing algorithms to manage terrestrial and satellite network resources efficiently by handling call handovers dynamically, and (2) to analyze and evaluate the algorithms by maximizing the traffic load handling capability (defined in erl/cell) over a wide range of terminal ratios (gamma) given an acceptable range of blocking probabilities. Two of the algorithms (G & S) in the proposed class perform extremely well for a wide range of gamma.

Traffic Generator (TrafficGen) Version 1.4.2: Users Guide

Science.gov (United States)

2016-06-01

the network with Transmission Control Protocol and User Datagram Protocol Internet Protocol traffic. Each node generating network traffic in an...TrafficGen Graphical User Interface (GUI) 3 3.1 Anatomy of the User Interface 3 3.2 Scenario Configuration and MGEN Files 4 4. Working with...for public release; distribution is unlimited. vi List of Figures Fig. 1 TrafficGen user interface

Queueing and traffic

NARCIS (Netherlands)

Baër, Niek

2015-01-01

Traffic jams are everywhere, some are caused by constructions or accidents but a large portion occurs naturally. These "natural" traffic jams are a result of variable driving speeds combined with a high number of vehicles. To prevent these traffic jams, we must understand traffic in general, and to

Traffic Games: Modeling Freeway Traffic with Game Theory.

Science.gov (United States)

Cortés-Berrueco, Luis E; Gershenson, Carlos; Stephens, Christopher R

2016-01-01

We apply game theory to a vehicular traffic model to study the effect of driver strategies on traffic flow. The resulting model inherits the realistic dynamics achieved by a two-lane traffic model and aims to incorporate phenomena caused by driver-driver interactions. To achieve this goal, a game-theoretic description of driver interaction was developed. This game-theoretic formalization allows one to model different lane-changing behaviors and to keep track of mobility performance. We simulate the evolution of cooperation, traffic flow, and mobility performance for different modeled behaviors. The analysis of these results indicates a mobility optimization process achieved by drivers' interactions.

Traffic planning for non-homogeneous traffic

Indian Academy of Sciences (India)

Vehicles based on similar traffic operating characteristics are grouped into ... of distances to the video monitor involved using a measuring wheel to mark ... Secondly, the observers reviewed the videotape to sample traffic entity ...... makes a strong case for including service lanes for slow moving vehicles for improving the.

Area-wide traffic calming for preventing traffic related injuries.

Science.gov (United States)

Bunn, F; Collier, T; Frost, C; Ker, K; Roberts, I; Wentz, R

2003-01-01

It is estimated that by 2020 road traffic crashes will have moved from ninth to third in the world disease burden ranking, as measured in disability adjusted life years, and second in developing countries. The identification of effective strategies for the prevention of traffic related injuries is of global health importance. Area-wide traffic calming schemes that discourage through traffic on residential roads is one such strategy. To evaluate the effectiveness of area-wide traffic calming in preventing traffic related crashes, injuries, and deaths. We searched the following electronic databases: Cochrane Injuries Group's Specialised Register, Cochrane Controlled Trials Register, MEDLINE, EMBASE and TRANSPORT (NTIS, TRIS, TRANSDOC). We searched the web sites of road safety organisations, handsearched conference proceedings, checked reference lists of relevant papers and contacted experts in the area. The search was not restricted by language or publication status. Randomised controlled trials, and controlled before-after studies of area-wide traffic calming schemes. Two reviewers independently extracted data on type of study, characteristics of intervention and control areas, and length of data collection periods. Before and after data were collected on the total number of road traffic crashes, all road user deaths and injuries, pedestrian-motor vehicle collisions and road user deaths. The statistical package STATA was used to calculate rate ratios for each study, which were then pooled to give an overall estimate using a random effects model. We found no randomised controlled trials, but 16 controlled before-after trials met our inclusion criteria. Seven studies were done in Germany, six in the UK, two in Australia and one in the Netherlands. There were no studies in low or middle income countries. Eight trials reported the number of road traffic crashes resulting in deaths. The pooled rate ratio was 0.63 (0.14, 2.59 95% CI). Sixteen studies reported the number

Traffic Light Options

DEFF Research Database (Denmark)

Jørgensen, Peter Løchte

This paper introduces, prices, and analyzes traffic light options. The traffic light option is an innovative structured OTC derivative developed independently by several London-based investment banks to suit the needs of Danish life and pension (L&P) companies, which must comply with the traffic...... 2006, and supervisory authorities in many other European countries have implemented similar regulation. Traffic light options are therefore likely to attract the attention of a wider audience of pension fund managers in the future. Focusing on the valuation of the traffic light option we set up a Black...... light scenarios. These stress scenarios entail drops in interest rates as well as in stock prices, and traffic light options are thus designed to pay off and preserve sufficient capital when interest rates and stock prices fall simultaneously. Sweden's FSA implemented a traffic light system in January...

Traffic Light Options

DEFF Research Database (Denmark)

Jørgensen, Peter Løchte

2007-01-01

This paper introduces, prices, and analyzes traffic light options. The traffic light option is an innovative structured OTC derivative developed independently by several London-based investment banks to suit the needs of Danish life and pension (L&P) companies, which must comply with the traffic...... 2006, and supervisory authorities in many other European countries have implemented similar regulation. Traffic light options are therefore likely to attract the attention of a wider audience of pension fund managers in the future. Focusing on the valuation of the traffic light option we set up a Black...... light scenarios. These stress scenarios entail drops in interest rates as well as in stock prices, and traffic light options are thus designed to pay off and preserve sufficient capital when interest rates and stock prices fall simultaneously. Sweden's FSA implemented a traffic light system in January...

Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes

DEFF Research Database (Denmark)

Fraile-Ramos, Alberto; Pelchen-Matthews, Annegret; Kledal, Thomas N

2002-01-01

and undergoes constitutive endocytosis and recycling. Here we studied the cellular distributions and trafficking of two other human cytomegalovirus chemokine receptor-like proteins, UL33 and US27, in transfected and human cytomegalovirus-infected cells. Immunofluorescence staining indicated that UL33 and US27......The human cytomegalovirus genome encodes four putative seven transmembrane domain chemokine receptor-like proteins. Although important in viral pathogenesis, little is known about the properties or functions of these proteins. We previously reported that US28 is located in endocytic vesicles......27 undergoes endocytosis. By immunogold labeling of cryosections and electron microscopy, UL33 was seen to localize to multivesicular bodies (MVBs or multivesicular endosomes). Electron microscopy analysis of human cytomegalovirus-infected cells showed that most virus particles wrapped individually...

Benefits of Imperfect Conflict Resolution Advisory Aids for Future Air Traffic Control.

Science.gov (United States)

Trapsilawati, Fitri; Wickens, Christopher D; Qu, Xingda; Chen, Chun-Hsien

2016-11-01

The aim of this study was to examine the human-automation interaction issues and the interacting factors in the context of conflict detection and resolution advisory (CRA) systems. The issues of imperfect automation in air traffic control (ATC) have been well documented in previous studies, particularly in conflict-alerting systems. The extent to which the prior findings can be applied to an integrated conflict detection and resolution system in future ATC remains unknown. Twenty-four participants were evenly divided into two groups corresponding to a medium- and a high-traffic density condition, respectively. In each traffic density condition, participants were instructed to perform simulated ATC tasks under four automation conditions, including reliable, unreliable with short time allowance to secondary conflict (TAS), unreliable with long TAS, and manual conditions. Dependent variables accounted for conflict resolution performance, workload, situation awareness, and trust in and dependence on the CRA aid, respectively. Imposing the CRA automation did increase performance and reduce workload as compared with manual performance. The CRA aid did not decrease situation awareness. The benefits of the CRA aid were manifest even when it was imperfectly reliable and were apparent across traffic loads. In the unreliable blocks, trust in the CRA aid was degraded but dependence was not influenced, yet the performance was not adversely affected. The use of CRA aid would benefit ATC operations across traffic densities. CRA aid offers benefits across traffic densities, regardless of its imperfection, as long as its reliability level is set above the threshold of assistance, suggesting its application for future ATC. © 2016, Human Factors and Ergonomics Society.

Noxious substances in the air - traffic planning measures - traffic of the future

Energy Technology Data Exchange (ETDEWEB)

Koestenberger, H

1985-01-01

Necessary bundle of measures: Extension of public transport and restriction of individual traffic, extension and activation of large main roads (by-passes) to unload inhabited areas, building garages, creation of residential streets, pedestrian precincts and cycle paths. The best possible traffic system can only be achieved if all means of transport are used efficiently. It is the duty of traffic planners to develop an overall traffic system with the aims of benefiting the whole community. Due to wrong slowing down of traffic, the reduction of emitted quantities of noxious substances from private cars can be counteracted by general slowing down of traffic; frequent braking and restarting. The functional separation of residential areas for living, areas for working, supply, education and leisure pursuits which has been aimed at in recent decades must be slowly changed. This could reduce the traffic and mobility (mixed functions). The aims for traffic of the future are: suitability for the environment, economy, safety and capacity. In an integrated road network, the traffic must take over the correct purpose of traffic. (orig.).

Traffic Infrastructure in the Development of the Croatian Traffic System

Directory of Open Access Journals (Sweden)

Damir Šimulčik

2012-10-01

Full Text Available The absence of a long-term traffic policy and of the policyof financing the constntction and maintenance of traffic infrastructurefacilities, represents a synthesis of numerous unresolvedrelations whose negative effects are felt in the overalleconomic and traffic development and consequently theevaluation of national potentials in the field. Adverse aspectcaused by the lack of a clear and feasible policy of financing thetraffic infrastructure facilities, is also a result of not having definedan adequate traffic policy, programme and strategiccourses of development, nor financing models that would be inaccordance with the market and economy system.This indicates that it is necessary to determine a policy forfinancing the constntction and maintenance of traffic infrastntcture,which has to be based on scientific development,team work, availability of plans and programmes to scientistsand experts, determined methodology based on marketing andeconomic logic in defining the programme and strategic tasksand assignments so as to make them feasible.In the near future, intensive preparations for investments inthe overall traffic sysiem are necessary, especially regarding thetraffic infrastntcture facilities - the pivotal points in the processof evaluating the traffic in our national tenitory. Croatia needsto define clearly its strategy in constructing and maintaining thegeneral traffic infrastructure, appointing at the same time thosewho will carry out the given tasks.

SIMULATION AND INVESTIGATION OF TIRE TREAD BLOCKS INTERACTION WITH ICE

Directory of Open Access Journals (Sweden)

Andrius Ružinskas

2017-12-01

Full Text Available The car tire is an essential subject analysing its interaction with the road. From tire’s tread condition, geometry and rubber compound depends grip and vehicle stability. This is especially relevant in winter time, when roads are covered with the layer of snow or ice. Generally, new tires are tested in real traffic conditions using vehicles. However, ensuring these conditions requires many resources and sometimes it could be a big challenge. For this reason, simulation of the tire interaction with the road becomes more important in nowadays tire researches. Since the tire is a complex engineering subject, the tire tread blocks could be separated for individual analysis. The interaction between the dry ice and the tread block with sipes was analysed using finite element analysis. The tread block was described using hyperelastic Mooney­Rivlin material model. The deformations, distribution of the contact pressure and shear stresses were obtained for the soft and hard rubber compounds with different vertical load conditions. Also a solid tread block interaction was analysed and it was found that values of contact pressure and shear stresses are much lower comparing to siped tread block.

Modeling pedestrian gap crossing index under mixed traffic condition.

Science.gov (United States)

Naser, Mohamed M; Zulkiple, Adnan; Al Bargi, Walid A; Khalifa, Nasradeen A; Daniel, Basil David

2017-12-01

There are a variety of challenges faced by pedestrians when they walk along and attempt to cross a road, as the most recorded accidents occur during this time. Pedestrians of all types, including both sexes with numerous aging groups, are always subjected to risk and are characterized as the most exposed road users. The increased demand for better traffic management strategies to reduce the risks at intersections, improve quality traffic management, traffic volume, and longer cycle time has further increased concerns over the past decade. This paper aims to develop a sustainable pedestrian gap crossing index model based on traffic flow density. It focusses on the gaps accepted by pedestrians and their decision for street crossing, where (Log-Gap) logarithm of accepted gaps was used to optimize the result of a model for gap crossing behavior. Through a review of extant literature, 15 influential variables were extracted for further empirical analysis. Subsequently, data from the observation at an uncontrolled mid-block in Jalan Ampang in Kuala Lumpur, Malaysia was gathered and Multiple Linear Regression (MLR) and Binary Logit Model (BLM) techniques were employed to analyze the results. From the results, different pedestrian behavioral characteristics were considered for a minimum gap size model, out of which only a few (four) variables could explain the pedestrian road crossing behavior while the remaining variables have an insignificant effect. Among the different variables, age, rolling gap, vehicle type, and crossing were the most influential variables. The study concludes that pedestrians' decision to cross the street depends on the pedestrian age, rolling gap, vehicle type, and size of traffic gap before crossing. The inferences from these models will be useful to increase pedestrian safety and performance evaluation of uncontrolled midblock road crossings in developing countries. Copyright © 2017 National Safety Council and Elsevier Ltd. All rights reserved.

The subapical compartment : a traffic center in membrane polarity development

NARCIS (Netherlands)

Hoekstra, D; Tyteca, D; van IJzendoorn, SCD

2004-01-01

Spatially separated apical and basolateral plasma membrane domains that have distinct functions and molecular compositions are a characteristic feature of epithelial cell polarity. The subapical compartment (SAC), also known as the common endosome (CE), where endocytic pathways from both surfaces

Peculiarities of Clutch Forming Rails and Wheel Block Construction

Science.gov (United States)

Shiler, V. V.; Galiev, I. I.; Shiler, A. V.

2018-03-01

The clutch of the wheel and rail is significantly influenced by the design features of the standard wheel pair, which are manifested in the presence of "parasitic" slipping of the wheels along the rails during its movement. The purpose of the presented work is to evaluate new design solutions for wheel sets. The research was carried out using methods of comparative simulation modelling and physical prototyping. A new design of the wheel pair (block wheel pair) is proposed, which features an independent rotation of all surfaces of the wheels in contact with the rails. The block construction of the wheel pair forms open mechanical contours with the track gauge, which completely eliminates the "parasitic" slippage. As a result, in the process of implementing traction or braking forces, the coupling coefficient of the block construction of the wheel pair is significantly higher than that of existing structures. In addition, in the run-out mode, the resistance to movement of the block wheel pair is half as much. All this will allow one to significantly reduce the energy consumption for traction of trains, wear of track elements and crew, and to increase the speed and safety of train traffic.

Impacts of Traffic Noise and Traffic Volume on Birds of Roadside Habitats

Directory of Open Access Journals (Sweden)

Kirsten M. Parris

2009-06-01

Full Text Available Roadside habitats are important for a range of taxa including plants, insects, mammals, and birds, particularly in developed countries in which large expanses of native vegetation have been cleared for agriculture or urban development. Although roadside vegetation may provide suitable habitat for many species, resident animals can be exposed to high levels of traffic noise, visual disturbance from passing vehicles, and the risk of collision with cars and trucks. Traffic noise can reduce the distance over which acoustic signals such as song can be detected, an effect known as acoustic interference or masking. Studies from the northern hemisphere show that the singing behavior of birds changes in the presence of traffic noise. We investigated the impact of traffic noise and traffic volume on two species of birds, the Grey Shrike-thrush (Colluricincla harmonica and the Grey Fantail (Rhipidura fuliginosa, at 58 roadside sites on the Mornington Peninsula, southeastern Australia. The lower singing Grey Shrike-thrush sang at a higher frequency in the presence of traffic noise, with a predicted increase in dominant frequency of 5.8 Hz/dB of traffic noise, and a total effect size of 209 Hz. In contrast, the higher singing Grey Fantail did not appear to change its song in traffic noise. The probability of detecting each species on a visit to a site declined substantially with increasing traffic noise and traffic volume, with several lines of evidence supporting a larger effect of traffic noise. Traffic noise could hamper detection of song by conspecifics, making it more difficult for birds to establish and maintain territories, attract mates and maintain pair bonds, and possibly leading to reduced breeding success in noisy roadside habitats. Closing key roads during the breeding season is a potential, but untested, management strategy to protect threatened bird species from traffic noise and collision with vehicles at the time of year when they are most

Protocol vulnerability detection based on network traffic analysis and binary reverse engineering.

Science.gov (United States)

Wen, Shameng; Meng, Qingkun; Feng, Chao; Tang, Chaojing

2017-01-01

Network protocol vulnerability detection plays an important role in many domains, including protocol security analysis, application security, and network intrusion detection. In this study, by analyzing the general fuzzing method of network protocols, we propose a novel approach that combines network traffic analysis with the binary reverse engineering method. For network traffic analysis, the block-based protocol description language is introduced to construct test scripts, while the binary reverse engineering method employs the genetic algorithm with a fitness function designed to focus on code coverage. This combination leads to a substantial improvement in fuzz testing for network protocols. We build a prototype system and use it to test several real-world network protocol implementations. The experimental results show that the proposed approach detects vulnerabilities more efficiently and effectively than general fuzzing methods such as SPIKE.

Evaluation of pedestrian mid-block road crossing behaviour using artificial neural network

Directory of Open Access Journals (Sweden)

B. Raghuram Kadali

2014-04-01

Full Text Available Pedestrians usually cross the road at mid-block locations in India because of the ease and convenience to reach their destination as compared to intersection locations. It is important to evaluate the pedestrian gap acceptance behavior at mid-block locations because of inadequate vehicular gaps under mixed traffic condition, which translates into the pedestrian road crossing behavior. The present study examines the pedestrian gap acceptance behaviour by employing an artificial neural network (ANN model for understanding the decision making process of pedestrians, i.e., acceptance or rejection of vehicular gaps at a mid-block location. From the results it has been found that the pedestrian rolling gap, frequency of attempt, vehicular gap size, pedestrian speed change condition and vehicle speed have major role in pedestrian gap acceptance. These results can lead to a better design of pedestrian crossing facilities where adequate gaps are not available in vehicular flow at mid-block crosswalk locations.

Modeling the heterogeneous traffic correlations in urban road systems using traffic-enhanced community detection approach

Science.gov (United States)

Lu, Feng; Liu, Kang; Duan, Yingying; Cheng, Shifen; Du, Fei

2018-07-01

A better characterization of the traffic influence among urban roads is crucial for traffic control and traffic forecasting. The existence of spatial heterogeneity imposes great influence on modeling the extent and degree of road traffic correlation, which is usually neglected by the traditional distance based method. In this paper, we propose a traffic-enhanced community detection approach to spatially reveal the traffic correlation in city road networks. First, the road network is modeled as a traffic-enhanced dual graph with the closeness between two road segments determined not only by their topological connection, but also by the traffic correlation between them. Then a flow-based community detection algorithm called Infomap is utilized to identify the road segment clusters. Evaluated by Moran's I, Calinski-Harabaz Index and the traffic interpolation application, we find that compared to the distance based method and the community based method, our proposed traffic-enhanced community based method behaves better in capturing the extent of traffic relevance as both the topological structure of the road network and the traffic correlations among urban roads are considered. It can be used in more traffic-related applications, such as traffic forecasting, traffic control and guidance.

A Signal Coordination Control Based on Traversing Empty between Mid-Block Street Crossing and Intersection

Directory of Open Access Journals (Sweden)

Changjiang Zheng

2012-01-01

Full Text Available To solve the problem in pedestrian Mid-Block street crossing, the method of signal coordination control between mid-block street crossing and intersection is researched in this paper. The paper proposes to use “distance-flow rate-time” graph as the tool for building coordination control system model which is for different situations of traffic control. Through alternating the linear optimization model, the system outputs the distribution of signal timing and system operational factors (delays in vehicles and mid-block street crossing. Finally, taking one section on the Taiping North Road in Nanjing as an example, the signal coordination control is carried out. And the results which are delays in the vehicles and mid-block street crossing are compared to those in the current distribution of signal timing.

Adaptive traffic signal control with actor-critic methods in a real-world traffic network with different traffic disruption events

NARCIS (Netherlands)

Aslani, Mohammad; Mesgari, Mohammad Saadi; Wiering, Marco

2017-01-01

The transportation demand is rapidly growing in metropolises, resulting in chronic traffic con-gestions in dense downtown areas. Adaptive traffic signal control as the principle part of in-telligent transportation systems has a primary role to effectively reduce traffic congestion by making a

Generation of stable lipid raft microdomains in the enterocyte brush border by selective endocytic removal of non-raft membrane.

Directory of Open Access Journals (Sweden)

E Michael Danielsen

Full Text Available The small intestinal brush border has an unusually high proportion of glycolipids which promote the formation of lipid raft microdomains, stabilized by various cross-linking lectins. This unique membrane organization acts to provide physical and chemical stability to the membrane that faces multiple deleterious agents present in the gut lumen, such as bile salts, digestive enzymes of the pancreas, and a plethora of pathogens. In the present work, we studied the constitutive endocytosis from the brush border of cultured jejunal explants of the pig, and the results indicate that this process functions to enrich the contents of lipid raft components in the brush border. The lipophilic fluorescent marker FM, taken up into early endosomes in the terminal web region (TWEEs, was absent from detergent resistant membranes (DRMs, implying an association with non-raft membrane. Furthermore, neither major lipid raft-associated brush border enzymes nor glycolipids were detected by immunofluorescence microscopy in subapical punctae resembling TWEEs. Finally, two model raft lipids, BODIPY-lactosylceramide and BODIPY-GM1, were not endocytosed except when cholera toxin subunit B (CTB was present. In conclusion, we propose that constitutive, selective endocytic removal of non-raft membrane acts as a sorting mechanism to enrich the brush border contents of lipid raft components, such as glycolipids and the major digestive enzymes. This sorting may be energetically driven by changes in membrane curvature when molecules move from a microvillar surface to an endocytic invagination.

Generation of stable lipid raft microdomains in the enterocyte brush border by selective endocytic removal of non-raft membrane.

Science.gov (United States)

Danielsen, E Michael; Hansen, Gert H

2013-01-01

The small intestinal brush border has an unusually high proportion of glycolipids which promote the formation of lipid raft microdomains, stabilized by various cross-linking lectins. This unique membrane organization acts to provide physical and chemical stability to the membrane that faces multiple deleterious agents present in the gut lumen, such as bile salts, digestive enzymes of the pancreas, and a plethora of pathogens. In the present work, we studied the constitutive endocytosis from the brush border of cultured jejunal explants of the pig, and the results indicate that this process functions to enrich the contents of lipid raft components in the brush border. The lipophilic fluorescent marker FM, taken up into early endosomes in the terminal web region (TWEEs), was absent from detergent resistant membranes (DRMs), implying an association with non-raft membrane. Furthermore, neither major lipid raft-associated brush border enzymes nor glycolipids were detected by immunofluorescence microscopy in subapical punctae resembling TWEEs. Finally, two model raft lipids, BODIPY-lactosylceramide and BODIPY-GM1, were not endocytosed except when cholera toxin subunit B (CTB) was present. In conclusion, we propose that constitutive, selective endocytic removal of non-raft membrane acts as a sorting mechanism to enrich the brush border contents of lipid raft components, such as glycolipids and the major digestive enzymes. This sorting may be energetically driven by changes in membrane curvature when molecules move from a microvillar surface to an endocytic invagination.

From Goods to Traffic:First Steps Toward an Auction-based Traffic Signal Controller

OpenAIRE

Raphael, Jeffery; Maskell, Simon; Sklar, Elizabeth Ida

2015-01-01

Traffic congestion is a major issue that plagues many urban road networks large and small. Traffic engineers are now leaning towards Intelligent Traffic Systems as many physical changes to road networks are costly or infeasible. Multi-Agent Systems (MAS) have become a popular paradigm for intelligent solutions to traffic management problems. There are many MAS approaches to traffic management that utilise market mechanisms. In market-based approaches, drivers “pay” to use the roadways. Howeve...

A Two-Stage Fuzzy Logic Control Method of Traffic Signal Based on Traffic Urgency Degree

OpenAIRE

Yan Ge

2014-01-01

City intersection traffic signal control is an important method to improve the efficiency of road network and alleviate traffic congestion. This paper researches traffic signal fuzzy control method on a single intersection. A two-stage traffic signal control method based on traffic urgency degree is proposed according to two-stage fuzzy inference on single intersection. At the first stage, calculate traffic urgency degree for all red phases using traffic urgency evaluation module and select t...

Properties of Traffic Risk Coefficient

Science.gov (United States)

Tang, Tie-Qiao; Huang, Hai-Jun; Shang, Hua-Yan; Xue, Yu

2009-10-01

We use the model with the consideration of the traffic interruption probability (Physica A 387(2008)6845) to study the relationship between the traffic risk coefficient and the traffic interruption probability. The analytical and numerical results show that the traffic interruption probability will reduce the traffic risk coefficient and that the reduction is related to the density, which shows that this model can improve traffic security.

Regulation of P2Y1 receptor traffic by sorting Nexin 1 is retromer independent.

Science.gov (United States)

Nisar, Shaista; Kelly, Eamonn; Cullen, Pete J; Mundell, Stuart J

2010-04-01

The activity and traffic of G-protein coupled receptors (GPCRs) is tightly controlled. Recent work from our laboratory has shown that P2Y(1) and P2Y(12) responsiveness is rapidly and reversibly modulated in human platelets and that the underlying mechanism requires receptor trafficking as an essential part of this process. However, little is known about the molecular mechanisms underlying P2Y receptor traffic. Sorting nexin 1 (SNX1) has been shown to regulate the endosomal sorting of cell surface receptors either to lysosomes where they are downregulated or back to the cell surface. These functions may in part be due to interactions of SNX1 with the mammalian retromer complex. In this study, we investigated the role of SNX1 in P2Y receptor trafficking. We show that P2Y(1) receptors recycle via a slow recycling pathway that is regulated by SNX1, whereas P2Y(12) receptors return to the cell surface via a rapid route that is SNX1 independent. SNX1 inhibition caused a dramatic increase in the rate of P2Y(1) receptor recycling, whereas inhibition of Vps26 and Vps35 known to be present in retromer had no effect, indicating that SNX1 regulation of P2Y(1) receptor recycling is retromer independent. In addition, inhibition of SNX4, 6 and 17 proteins did not affect P2Y(1) receptor recycling. SNX1 has also been implicated in GPCR degradation; however, we provide evidence that P2Y receptor degradation is SNX1 independent. These data describe a novel function of SNX1 in the regulation of P2Y(1) receptor recycling and suggest that SNX1 plays multiple roles in endocytic trafficking of GPCRs.

Protocol vulnerability detection based on network traffic analysis and binary reverse engineering.

Directory of Open Access Journals (Sweden)

Shameng Wen

Full Text Available Network protocol vulnerability detection plays an important role in many domains, including protocol security analysis, application security, and network intrusion detection. In this study, by analyzing the general fuzzing method of network protocols, we propose a novel approach that combines network traffic analysis with the binary reverse engineering method. For network traffic analysis, the block-based protocol description language is introduced to construct test scripts, while the binary reverse engineering method employs the genetic algorithm with a fitness function designed to focus on code coverage. This combination leads to a substantial improvement in fuzz testing for network protocols. We build a prototype system and use it to test several real-world network protocol implementations. The experimental results show that the proposed approach detects vulnerabilities more efficiently and effectively than general fuzzing methods such as SPIKE.

Analysis of vehicular traffic flow in the major areas of Kuala Lumpur utilizing open-traffic

Science.gov (United States)

Manogaran, Saargunawathy; Ali, Muhammad; Yusof, Kamaludin Mohamad; Suhaili, Ramdhan

2017-09-01

Vehicular traffic congestion occurs when a large number of drivers are overcrowded on the road and the traffic flow does not run smoothly. Traffic congestion causes chaos on the road and interruption to daily activities of users. Time consumed on road give lots of negative effects on productivity, social behavior, environmental and cost to economy. Congestion is worsens and leads to havoc during the emergency such as flood, accidents, road maintenance and etc., where behavior of traffic flow is always unpredictable and uncontrollable. Real-time and historical traffic data are critical inputs for most traffic flow analysis applications. Researcher attempt to predict traffic using simulations as there is no exact model of traffic flow exists due to its high complexity. Open Traffic is an open source platform available for traffic data analysis linked to Open Street Map (OSM). This research is aimed to study and understand the Open Traffic platform. The real-time traffic flow pattern in Kuala Lumpur area was successfully been extracted and analyzed using Open Traffic. It was observed that the congestion occurs on every major road in Kuala Lumpur and most of it owes to the offices and the economic and commercial centers during rush hours. At some roads the congestion occurs at night due to the tourism activities.

Rab7: roles in membrane trafficking and disease.

Science.gov (United States)

Zhang, Ming; Chen, Li; Wang, Shicong; Wang, Tuanlao

2009-06-01

The endocytosis pathway controls multiple cellular and physiological events. The lysosome is the destination of newly synthesized lysosomal hydrolytic enzymes. Internalized molecules or particles are delivered to the lysosome for degradation through sequential transport along the endocytic pathway. The endocytic pathway is also emerging as a signalling platform, in addition to the well-known role of the plasma membrane for signalling. Rab7 is a late endosome-/lysosome-associated small GTPase, perhaps the only lysosomal Rab protein identified to date. Rab7 plays critical roles in the endocytic processes. Through interaction with its partners (including upstream regulators and downstream effectors), Rab7 participates in multiple regulation mechanisms in endosomal sorting, biogenesis of lysosome [or LRO (lysosome-related organelle)] and phagocytosis. These processes are closely related to substrates degradation, antigen presentation, cell signalling, cell survival and microbial pathogen infection. Consistently, mutations or dysfunctions of Rab7 result in traffic disorders, which cause various diseases, such as neuropathy, cancer and lipid metabolism disease. Rab7 also plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Here, we give a brief review on the central role of Rab7 in endosomal traffic and summarize the studies focusing on the participation of Rab7 in disease pathogenesis. The underlying mechanism governed by Rab7 and its partners will also be discussed.

Land use regression modeling of intra-urban residential variability in multiple traffic-related air pollutants

Directory of Open Access Journals (Sweden)

Baxter Lisa K

2008-05-01

Full Text Available Abstract Background There is a growing body of literature linking GIS-based measures of traffic density to asthma and other respiratory outcomes. However, no consensus exists on which traffic indicators best capture variability in different pollutants or within different settings. As part of a study on childhood asthma etiology, we examined variability in outdoor concentrations of multiple traffic-related air pollutants within urban communities, using a range of GIS-based predictors and land use regression techniques. Methods We measured fine particulate matter (PM2.5, nitrogen dioxide (NO2, and elemental carbon (EC outside 44 homes representing a range of traffic densities and neighborhoods across Boston, Massachusetts and nearby communities. Multiple three to four-day average samples were collected at each home during winters and summers from 2003 to 2005. Traffic indicators were derived using Massachusetts Highway Department data and direct traffic counts. Multivariate regression analyses were performed separately for each pollutant, using traffic indicators, land use, meteorology, site characteristics, and central site concentrations. Results PM2.5 was strongly associated with the central site monitor (R2 = 0.68. Additional variability was explained by total roadway length within 100 m of the home, smoking or grilling near the monitor, and block-group population density (R2 = 0.76. EC showed greater spatial variability, especially during winter months, and was predicted by roadway length within 200 m of the home. The influence of traffic was greater under low wind speed conditions, and concentrations were lower during summer (R2 = 0.52. NO2 showed significant spatial variability, predicted by population density and roadway length within 50 m of the home, modified by site characteristics (obstruction, and with higher concentrations during summer (R2 = 0.56. Conclusion Each pollutant examined displayed somewhat different spatial patterns

Simulating the impacts of on-street vehicle parking on traffic operations on urban streets using cellular automation

Science.gov (United States)

Chen, Jingxu; Li, Zhibin; Jiang, Hang; Zhu, Senlai; Wang, Wei

2017-02-01

In recent years, many bicycle lanes on urban streets are replaced with vehicle parking places. Spaces for bicycle riding are reduced, resulting in changes in bicycle and vehicle operational features. The objective of this study is to estimate the impacts of on-street parking on heterogeneous traffic operation on urban streets. A cellular automaton (CA) model is developed and calibrated to simulate bicycle lane-changing on streets with on-street parking. Two types of street segments with different bicycle lane width are considered. From the simulation, two types of conflicts between bicycles and vehicles are identified which are frictional conflicts and blocking conflicts. Factors affecting the frequency of conflicts are also identified. Based on the results, vehicle delay is estimated for various traffic situations considering the range of occupancy levels for on-street parking. Later, a numerical network example is analyzed to estimate the network impact of on-street parking on traffic assignment and operation. Findings of the study are helpful to policies and design regarding on-street vehicle parking to improve the efficiency of traffic operations.

Traffic safety strategies

Directory of Open Access Journals (Sweden)

V. Sadauskas

2003-04-01

Full Text Available Fast development of the number of vehicles is closely related not only to large benefit for the public but also to certain undesirable social and economic consequences. Firstly - large numbers of injured and killed people are involved into the accidents. The target to improve traffic safety situation in Lithuania can be reached only after the detailed evaluation of transport system, environment, traffic participants, road and vehicle. Taking into consideration the accident situation in Lithuania and its causes the followings priority trends are suggested: The improvement of the coordination of road traffic safety system, the training and education of road users, the explanation of the importance of traffic safety and its propagation, the improvement of traffic conditions. Recommendations and proposals for differentiated criterion of maximum speed limit selection taking into account different factors are provided in the work.

Travelers ability to observe changes in traffic intensities and traffic light settings

NARCIS (Netherlands)

Vreeswijk, Jacob Dirk; Do, Michael; Middag, Wilco; Martens, Marieke Hendrikje; van Berkum, Eric C.; van Arem, Bart; ITSC,

2011-01-01

Travel choice behavior is an important determinant in traffic and subject to human imperfection and bounded rationality. In decision-making processes travelers seldom act perfectly rational. Traffic models and traffic network management measure could become more realistic and effective, if

Traffic breakdown at a signal: classical theory versus the three-phase theory of city traffic

International Nuclear Information System (INIS)

Kerner, Boris S; Schreckenberg, Michael; Klenov, Sergey L

2014-01-01

Physical reasons for a crucial difference between the results of a three-phase theory developed recently (Kerner 2011 Phys. Rev. E 84 045102(R); 2013 Europhys. Lett. 102 28010; 2014 Physica A 397 76) and the classical theory are explained. Microscopic characteristics of traffic passing a traffic signal during the green signal phase and their dependence on the duration of the green phase have been found. It turns out that a moving synchronized flow pattern (MSP), which occurs in under-saturated traffic at the signal, causes ‘compression’ of traffic flow: the rate of MSP discharge can be considerably larger than the saturation flow rate of the classical traffic theory of city traffic. This leads to a considerably larger rate of traffic passing the signal in comparison with the saturation flow rate. This effect together with traffic behavior at the upstream queue front explains the metastability of under-saturated traffic with respect to a random time-delayed traffic breakdown. (paper)

Real time traffic models, decision support for traffic management

NARCIS (Netherlands)

Wismans, Luc Johannes Josephus; de Romph, E.; Friso, K.; Zantema, K.

2014-01-01

Reliable and accurate short-term traffic state prediction can improve the performance of real-time traffic management systems significantly. Using this short-time prediction based on current measurements delivered by advanced surveillance systems will support decision-making processes on various

Real Time Traffic Models, Decision Support for Traffic Management

NARCIS (Netherlands)

Wismans, L.; De Romph, E.; Friso, K.; Zantema, K.

2014-01-01

Reliable and accurate short-term traffic state prediction can improve the performance of real-time traffic management systems significantly. Using this short-time prediction based on current measurements delivered by advanced surveillance systems will support decision-making processes on various

Remark on the Causes of Traffic Accidents and Traffic Awareness: Examples of Usak Province

Directory of Open Access Journals (Sweden)

Ercan ÖZEN

2014-01-01

Full Text Available Traffic accidents cause important losses on the social and economics structure of countries. While economic losses are able to be compensated in a short time, it isn’t possible to compensate social and communal losses. This study tackles with not the economic aspect of traffic accidents but the social dimension, evaluates the causes of the traffic accidents with respect to views of individuals on traffic and aims to measure the levels of awareness of individuals about traffic. To achieve these goals, a group of 506 people were surveyed in Uşak province and the acquired data were analyzed via one-way ANOVA test in SPSS 16 program. According to the analysis results, drivers and pedestrians are considered to have significant flaws in traffic accidents. But alongside this thought, the idea that traffic accidents are caused by the road having technical and physical problems has come to the fore. This results present a valid motive for the established approach “Vision Zero” , being practised in Sweden, to be adopted in Turkey. When the level of awareness about traffic is examined, it is seen that individuals generally have got inadequate information related traffic rules and traffic authorities. Besides, the fact that individuals are inadequate in terms of courtesy and respect in traffic and that more serious efforts on traffic education is needed to be spent come out as the important findings of this study. The findings of this study can be thought as a directive tool to the policy makers.

Examining perimeter gating control of urban traffic networkswith locally adaptive traffic signals

NARCIS (Netherlands)

Keyvan Ekbatani, M.; Gao, X.; Gayah, V.V.; Knoop, V.L.

2015-01-01

Traditionally, urban traffic is controlled by traffic lights. Recent findings of the Macroscopic or Network Fundamental Diagram (MFD or NFD) have led to the development of novel traffic control strategies that can be applied at a networkwide level. One pertinent example is perimeter flow control

Traffic management simulation development : summary.

Science.gov (United States)

2011-01-01

Increasingly, Florida traffic is monitored electronically by components of the Intelligent Traffic System (ITS), which send data to regional traffic management centers and assist management of traffic flows and incident response using software called...

Admission Control for Multiservices Traffic in Hierarchical Mobile IPv6 Networks by Using Fuzzy Inference System

Directory of Open Access Journals (Sweden)

Jung-Shyr Wu

2012-01-01

Full Text Available CAC (Call Admission Control plays a significant role in providing QoS (Quality of Service in mobile wireless networks. In addition to much research that focuses on modified Mobile IP to get better efficient handover performance, CAC should be introduced to Mobile IP-based network to guarantee the QoS for users. In this paper, we propose a CAC scheme which incorporates multiple traffic types and adjusts the admission threshold dynamically using fuzzy control logic to achieve better usage of resources. The method can provide QoS in Mobile IPv6 networks with few modifications on MAP (Mobility Anchor Point functionality and slight change in BU (Binding Update message formats. According to the simulation results, the proposed scheme presents good performance of voice and video traffic at the expenses of poor performance on data traffic. It is evident that these CAC schemes can reduce the probability of the handoff dropping and the cell overload and limit the probability of the new call blocking.

High-level traffic-violation detection for embedded traffic analysis

NARCIS (Netherlands)

Vijverberg, J.A.; de Koning, A.H.M.; Han, Jungong; de With, P.H.N.; Cornelissen, D.

2007-01-01

This paper presents the design of a robust and real-time traffic-violation detection system for cameras on intersections. We use background segmentation and a novel road-model to obtain the candidate traffic participants. A region-based tracking system, equipped with static occlusion-reasoning,

Trajectory Based Traffic Analysis

DEFF Research Database (Denmark)

Krogh, Benjamin Bjerre; Andersen, Ove; Lewis-Kelham, Edwin

2013-01-01

We present the INTRA system for interactive path-based traffic analysis. The analyses are developed in collaboration with traffic researchers and provide novel insights into conditions such as congestion, travel-time, choice of route, and traffic-flow. INTRA supports interactive point-and-click a......We present the INTRA system for interactive path-based traffic analysis. The analyses are developed in collaboration with traffic researchers and provide novel insights into conditions such as congestion, travel-time, choice of route, and traffic-flow. INTRA supports interactive point......-and-click analysis, due to a novel and efficient indexing structure. With the web-site daisy.aau.dk/its/spqdemo/we will demonstrate several analyses, using a very large real-world data set consisting of 1.9 billion GPS records (1.5 million trajectories) recorded from more than 13000 vehicles, and touching most...

Dynamic segment shared protection for multicast traffic in meshed wavelength-division-multiplexing optical networks

Science.gov (United States)

Liao, Luhua; Li, Lemin; Wang, Sheng

2006-12-01

We investigate the protection approach for dynamic multicast traffic under shared risk link group (SRLG) constraints in meshed wavelength-division-multiplexing optical networks. We present a shared protection algorithm called dynamic segment shared protection for multicast traffic (DSSPM), which can dynamically adjust the link cost according to the current network state and can establish a primary light-tree as well as corresponding SRLG-disjoint backup segments for a dependable multicast connection. A backup segment can efficiently share the wavelength capacity of its working tree and the common resources of other backup segments based on SRLG-disjoint constraints. The simulation results show that DSSPM not only can protect the multicast sessions against a single-SRLG breakdown, but can make better use of the wavelength resources and also lower the network blocking probability.

Right-­turn traffic volume adjustment in traffic signal warrant analysis : final report.

Science.gov (United States)

2016-05-06

This report was based on the research project, Right-Turn Traffic Volume Adjustment in Traffic Signal Warrants, sponsored by the Nevada Department of Transportation (NDOT) and SOLARIS. Right-turn traffic does not affect intersection performance in th...

Multicore-Optimized Wavefront Diamond Blocking for Optimizing Stencil Updates

KAUST Repository

Malas, T.

2015-07-02

The importance of stencil-based algorithms in computational science has focused attention on optimized parallel implementations for multilevel cache-based processors. Temporal blocking schemes leverage the large bandwidth and low latency of caches to accelerate stencil updates and approach theoretical peak performance. A key ingredient is the reduction of data traffic across slow data paths, especially the main memory interface. In this work we combine the ideas of multicore wavefront temporal blocking and diamond tiling to arrive at stencil update schemes that show large reductions in memory pressure compared to existing approaches. The resulting schemes show performance advantages in bandwidth-starved situations, which are exacerbated by the high bytes per lattice update case of variable coefficients. Our thread groups concept provides a controllable trade-off between concurrency and memory usage, shifting the pressure between the memory interface and the CPU. We present performance results on a contemporary Intel processor.

Multicore-Optimized Wavefront Diamond Blocking for Optimizing Stencil Updates

KAUST Repository

Malas, T.; Hager, G.; Ltaief, Hatem; Stengel, H.; Wellein, G.; Keyes, David E.

2015-01-01

The importance of stencil-based algorithms in computational science has focused attention on optimized parallel implementations for multilevel cache-based processors. Temporal blocking schemes leverage the large bandwidth and low latency of caches to accelerate stencil updates and approach theoretical peak performance. A key ingredient is the reduction of data traffic across slow data paths, especially the main memory interface. In this work we combine the ideas of multicore wavefront temporal blocking and diamond tiling to arrive at stencil update schemes that show large reductions in memory pressure compared to existing approaches. The resulting schemes show performance advantages in bandwidth-starved situations, which are exacerbated by the high bytes per lattice update case of variable coefficients. Our thread groups concept provides a controllable trade-off between concurrency and memory usage, shifting the pressure between the memory interface and the CPU. We present performance results on a contemporary Intel processor.

Automated mixed traffic vehicle design AMTV 2

Science.gov (United States)

Johnston, A. R.; Marks, R. A.; Cassell, P. L.

1982-01-01

The design of an improved and enclosed Automated Mixed Traffic Transit (AMTT) vehicle is described. AMTT is an innovative concept for low-speed tram-type transit in which suitable vehicles are equipped with sensors and controls to permit them to operate in an automated mode on existing road or walkway surfaces. The vehicle chassis and body design are presented in terms of sketches and photographs. The functional design of the sensing and control system is presented, and modifications which could be made to the baseline design for improved performance, in particular to incorporate a 20-mph capability, are also discussed. The vehicle system is described at the block-diagram-level of detail. Specifications and parameter values are given where available.

SOME EMPIRICAL RELATIONS BETWEEN TRAVEL SPEED, TRAFFIC VOLUME AND TRAFFIC COMPOSITION IN URBAN ARTERIALS

Directory of Open Access Journals (Sweden)

Eleni I. VLAHOGIANNI, Ph.D.

2007-01-01

Full Text Available The effects of traffic mix (the percentage of cars, trucks, buses and so on are of particular interest in the speed-volume relationship in urban signalized arterials under various geometric and control characteristics. The paper presents some empirical observations on the relation between travel speed, traffic volume and traffic composition in urban signalized arterials. A methodology based on emerging self-organizing structures of neural networks to identify regions in the speed-volume relationship with respect to traffic composition and Bayesian networks to evaluate the effect of different types of motorized vehicles on prevailing traffic conditions is proposed. Results based on data from a large urban network indicate that the variability in traffic conditions can be described by eight regions in speed-volume relationship with respect to traffic composition. Further evaluation of the effect of motorized vehicles in each region separately indicates that the effect of traffic composition decreases with the onset of congestion. Moreover, taxis and motorcycles are the primary affecting parameter of the form of the speed-volume relationship in urban arterials.

The impact of traffic sign deficit on road traffic accidents in Nigeria.

Science.gov (United States)

Ezeibe, Christian; Ilo, Chukwudi; Oguonu, Chika; Ali, Alphonsus; Abada, Ifeanyi; Ezeibe, Ezinwanne; Oguonu, Chukwunonso; Abada, Felicia; Izueke, Edwin; Agbo, Humphrey

2018-04-04

This study assesses the impact of traffic sign deficit on road traffic accidents in Nigeria. The participants were 720 commercial vehicle drivers. While simple random sampling was used to select 6 out of 137 federal highways, stratified random sampling was used to select six categories of commercial vehicle drivers. The study used qual-dominant mixed methods approach comprising key informant interviews; group interviews; field observation; policy appraisal and secondary literature on traffic signs. Result shows that the failure of government to provide and maintain traffic signs in order to guide road users through the numerous accident black spots on the highways is the major cause of road accidents in Nigeria. The study argues that provision and maintenance of traffic signs present opportunity to promoting safety on the highways and achieving the sustainable development goals.

Using Traffic Conflict Method in Evaluating Traffic Safety at the Reconstructed Intersection

Directory of Open Access Journals (Sweden)

Zdravko Bukljaš

2002-05-01

Full Text Available As part of organised social system, traffic is subjected togeneral social tendency towards adequate safety and sustainabilityof relations in such a system, probabilistically marked bythe risk of danger. Inte1polation of subjective factor facilitatesthe occwTence of negative phenomena. Road traffic system ischaracterised by extremely massive participation in traffic, contributingthus to a greater possibility of negative features characteristicfor imperfect human mechanism. This is precisely thereason why this paper deals with the problem of traffic safety onthe concrete example of the intersection between the SavskaStreet and the Slavonska and LjubljanskaAvenues over the periodof time prior to constmcting the new unde1pass solution,and the period of time immediately after the construction workswere completed. The used data have been provided by the TrafficPolice Department - Lucko.

Web traffic and firm performance

DEFF Research Database (Denmark)

Farooq, Omar; Aguenaou, Samir

2013-01-01

Does the traffic generated by websites of firms signal anything to stock market participants? Does higher web-traffic translate into availability of more information and therefore lower agency problems? And if answers to above questions are in affirmative, does higher web-traffic traffic translate...... into better firm performance? This paper aims to answer these questions by documenting a positive relationship between the extent of web-traffic and firm performance in the MENA region during the 2010. We argue that higher web-traffic lowers the agency problems in firms by disseminating more information...... to stock market participants. Consequently, lower agency problems translate into better performance. Furthermore, we also show that agency reducing role of web-traffic is more pronounced in regimes where information environment is already bad. For example, our results show stronger impact of web...

Research on the Method of Traffic Organization and Optimization Based on Dynamic Traffic Flow Model

Directory of Open Access Journals (Sweden)

Shu-bin Li

2017-01-01

Full Text Available The modern transportation system is becoming sluggish by traffic jams, so much so that it can harm the economic and society in our country. One of the reasons is the surging vehicles day by day. Another reason is the shortage of the traffic supply seriously. But the most important reason is that the traffic organization and optimization hardly met the conditions of modern transport development. In this paper, the practical method of the traffic organization and optimization used in regional area is explored by the dynamic traffic network analysis method. Firstly, the operational states of the regional traffic network are obtained by simulation method based on the self-developed traffic simulation software DynaCHINA, in which the improved traffic flow simulation model was proposed in order to be more suitable for actual domestic urban transport situation. Then the appropriated optimization model and algorithm were proposed according to different optimized content and organization goals, and the traffic simulation processes more suitable to regional optimization were designed exactly. Finally, a regional network in Tai’an city was selected as an example. The simulation results show that the proposed method is effective and feasible. It can provide strong scientific and technological support for the traffic management department.

Intersectin goes nuclear: secret life of an endocytic protein.

Science.gov (United States)

Alvisi, Gualtiero; Paolini, Lucia; Contarini, Andrea; Zambarda, Chiara; Di Antonio, Veronica; Colosini, Antonella; Mercandelli, Nicole; Timmoneri, Martina; Palù, Giorgio; Caimi, Luigi; Ricotta, Doris; Radeghieri, Annalisa

2018-04-27

Intersectin 1-short (ITSN1-s) is a 1220 amino acid ubiquitously expressed scaffold protein presenting a multidomain structure that allows to spatiotemporally regulate the functional interaction of a plethora of proteins. Besides its well-established role in endocytosis, ITSN1-s is involved in the regulation of cell signaling and is implicated in tumorigenesis processes, although the signaling pathways involved are still poorly understood. Here, we identify ITSN1-s as a nucleocytoplasmic trafficking protein. We show that, by binding to importin (IMP)α, a small fraction of ITSN1-s localizes in the cell nucleus at the steady state, where it preferentially associates with the nuclear envelope and interacts with lamin A/C. However, upon pharmacological ablation of chromosome region maintenance 1 (CRM-1)-dependent nuclear export pathway, the protein accumulates into the nucleus, thus revealing its moonlighting nature. Analysis of deletion mutants revealed that the coiled coil (CC) and Src homology (SH3) regions play the major role in its nucleocytoplasmic shuttling. While no evidence of nuclear localization signal (NLS) was detected in the CC region, a functional bipartite NLS was identified within the SH3D region of ITSN1-s (RKKNPGGWWEGELQARGKKRQIGW-1127), capable of conferring energy-dependent nuclear accumulation to reporter proteins and whose mutational ablation affects nuclear import of the whole SH3 region. Thus, ITSN1-s is an endocytic protein, which shuttles between the nucleus and the cytoplasm in a CRM-1- and IMPα-dependent fashion. © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

[Traffic deaths and traffic injuries: also an economic problem for society].

Science.gov (United States)

Martinoli, S

1993-02-09

Based on an epidemiological observation on traffic accidents in the Swiss canton of Ticino, 1985, the following statement is possible: In Switzerland, 900 people die every year as a result of traffic casualties. Many victims of these accidents will be disabled for life. Direct and indirect costs of traffic injuries reach 3 billion Swiss francs a year. Only a small amount (6%) is devoted to medical treatment. The biggest part is due as compensation for lost income, disability allocations and loss of productivity. Among the avoidable fatalities those caused by traffic accidents have a very undesirable effect, because they involve mainly the young. More efforts should be undertaken to lower the mortality on the road, because it changes the Swiss population pyramid in a significant manner.

Analisis Penerapan Metode Transmitter Receiver Unit (TRU Upgrading Untuk Mengatasi Traffic Congestion Jaringan GSM Pada BTS Area Purwokerto Kota

Directory of Open Access Journals (Sweden)

Alfin Hikmaturokhman

2011-05-01

Full Text Available Semakin banyaknya pengguna selular maka akan semakin banyak trafik yang akan tertampung. Trafik yang melebihi kapasitas kanal yang disediakan dapat menyebabkan kondisi Traffic Congestion. Untuk menanganinya diperlukan metode penambahan kapasitas kanal agar semua trafik dapat tertampung dengan baik. Metode ini disebut dengan TRU Upgrading. Transmitter Receiver Unit (TRU adalah hardware yang terletak pada Radio Base Station dalam BTS yang berisi slot-slot kanal sedangkan metode TRU Upgrading adalah metode dengan menambahkan/upgrade kapasitas kanal yang tersedia dari konfigurasi TRU yang telah ada sebelumnya, misalkan pada BTS Pabuaran memiliki konfigurasi 3x2x3 karena terjadi kejenuhan pelanggan maka konfigurasi TRU diupgrade menjadi 3x4x3. Perubahan konfigurasi TRU maka merubah konfigurasi BTS-nya serta menambah kapasitas kanalnya. Key Performance Indicator (KPI yang baik pada Indosat adalah menggunakan batas GoS 2%. Nilai GoS ini dikaitkan dengan tabel Erlang untuk mendapatkan sebuah nilai intensitas trafik. Jika nilai intensitas trafik konfigurasi TRU yang digunakan kurang dari nilai intensitas trafik pelanggan maka disebut traffic congestion. Sebagai akibat dari traffic congestion adalah kondisi blocking. TRU Upgrading ini dilakukan dengan harapan nilai blocking panggilan menjadi 0 %. Pada Purwokerto kota, diterapkan  TRU Upgrading untuk cell Grendeng 3, Pabuaran 2, dan Unsoed 1 karena trafik pelanggan yang terjadi melebihi nilai intensitas trafik dari konfigurasi TRU yang digunakan.   Untuk cell Unsoed 1 dan Grendeng 3 meski telah dilakukan TRU Upgrading menjadi 4 buah TRU tetap terjadi traffic congestion sebesar 8 sampai dengan 15 Erlang dikarenakan pada cell-cell ini mengcover area yang padat penduduk. Sedang untuk Pabuaran 2 penerapan TRU upgrading mencapai keefektifan sebesar 100%.

Visualization of Traffic Accidents

Science.gov (United States)

Wang, Jie; Shen, Yuzhong; Khattak, Asad

2010-01-01

Traffic accidents have tremendous impact on society. Annually approximately 6.4 million vehicle accidents are reported by police in the US and nearly half of them result in catastrophic injuries. Visualizations of traffic accidents using geographic information systems (GIS) greatly facilitate handling and analysis of traffic accidents in many aspects. Environmental Systems Research Institute (ESRI), Inc. is the world leader in GIS research and development. ArcGIS, a software package developed by ESRI, has the capabilities to display events associated with a road network, such as accident locations, and pavement quality. But when event locations related to a road network are processed, the existing algorithm used by ArcGIS does not utilize all the information related to the routes of the road network and produces erroneous visualization results of event locations. This software bug causes serious problems for applications in which accurate location information is critical for emergency responses, such as traffic accidents. This paper aims to address this problem and proposes an improved method that utilizes all relevant information of traffic accidents, namely, route number, direction, and mile post, and extracts correct event locations for accurate traffic accident visualization and analysis. The proposed method generates a new shape file for traffic accidents and displays them on top of the existing road network in ArcGIS. Visualization of traffic accidents along Hampton Roads Bridge Tunnel is included to demonstrate the effectiveness of the proposed method.

The Stability of Multi-modal Traffic Network

International Nuclear Information System (INIS)

Han Linghui; Sun Huijun; Zhu Chengjuan; Jia Bin; Wu Jianjun

2013-01-01

There is an explicit and implicit assumption in multimodal traffic equilibrium models, that is, if the equilibrium exists, then it will also occur. The assumption is very idealized; in fact, it may be shown that the quite contrary could happen, because in multimodal traffic network, especially in mixed traffic conditions the interaction among traffic modes is asymmetric and the asymmetric interaction may result in the instability of traffic system. In this paper, to study the stability of multimodal traffic system, we respectively present the travel cost function in mixed traffic conditions and in traffic network with dedicated bus lanes. Based on a day-to-day dynamical model, we study the evolution of daily route choice of travelers in multimodal traffic network using 10000 random initial values for different cases. From the results of simulation, it can be concluded that the asymmetric interaction between the cars and buses in mixed traffic conditions can lead the traffic system to instability when traffic demand is larger. We also study the effect of travelers' perception error on the stability of multimodal traffic network. Although the larger perception error can alleviate the effect of interaction between cars and buses and improve the stability of traffic system in mixed traffic conditions, the traffic system also become instable when the traffic demand is larger than a number. For all cases simulated in this study, with the same parameters, traffic system with dedicated bus lane has better stability for traffic demand than that in mixed traffic conditions. We also find that the network with dedicated bus lane has higher portion of travelers by bus than it of mixed traffic network. So it can be concluded that building dedicated bus lane can improve the stability of traffic system and attract more travelers to choose bus reducing the traffic congestion. (general)

Right-\\0xADturn traffic volume adjustment in traffic signal warrant analysis : final report.

Science.gov (United States)

2016-05-06

This report was based on the research project, Right-Turn Traffic Volume Adjustment in : Traffic Signal Warrants, sponsored by the Nevada Department of Transportation (NDOT) : and SOLARIS. Right-turn traffic does not affect intersection performance i...

An efficient, block-by-block algorithm for inverting a block tridiagonal, nearly block Toeplitz matrix

International Nuclear Information System (INIS)

Reuter, Matthew G; Hill, Judith C

2012-01-01

We present an algorithm for computing any block of the inverse of a block tridiagonal, nearly block Toeplitz matrix (defined as a block tridiagonal matrix with a small number of deviations from the purely block Toeplitz structure). By exploiting both the block tridiagonal and the nearly block Toeplitz structures, this method scales independently of the total number of blocks in the matrix and linearly with the number of deviations. Numerical studies demonstrate this scaling and the advantages of our method over alternatives.

Porcine sialoadhesin (CD169/Siglec-1 is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages.

Directory of Open Access Journals (Sweden)

Peter L Delputte

Full Text Available Sialoadhesin is exclusively expressed on specific subpopulations of macrophages. Since sialoadhesin-positive macrophages are involved in inflammatory autoimmune diseases, such as multiple sclerosis, and potentially in the generation of immune responses, targeted delivery of drugs, toxins or antigens via sialoadhesin-specific immunoconjugates may prove a useful therapeutic strategy. Originally, sialoadhesin was characterized as a lymphocyte adhesion molecule, though recently its involvement in internalization of sialic acid carrying pathogens was shown, suggesting that sialoadhesin is an endocytic receptor. In this report, we show that porcine sialoadhesin-specific antibodies and F(ab'₂ fragments trigger sialoadhesin internalization, both in primary porcine macrophages and in cells expressing recombinant porcine sialoadhesin. Using chemical inhibitors, double immunofluorescence stainings and dominant-negative constructs, porcine sialoadhesin internalization was shown to be clathrin- and Eps15-dependent and to result in targeting to early endosomes but not lysosomes. Besides characterizing the sialoadhesin endocytosis mechanism, two sialoadhesin-specific immunoconjugates were evaluated. We observed that porcine sialoadhesin-specific immunotoxins efficiently kill sialoadhesin-expressing macrophages. Furthermore, porcine sialoadhesin-specific albumin immunoconjugates were shown to be internalized in macrophages and immunization with these immunoconjugates resulted in a rapid and robust induction of albumin-specific antibodies, this compared to immunization with albumin alone. Together, these data expand sialoadhesin functionality and show that it can function as an endocytic receptor, a feature that cannot only be misused by sialic acid carrying pathogens, but that may also be used for specific targeting of toxins or antigens to sialoadhesin-expressing macrophages.

Traffic Flow Visualization and Control

National Research Council Canada - National Science Library

Larson, Robert

1999-01-01

.... Air Force Research Laboratory. It is a video-camera-based, wide-area, traffic surveillance and detection system that provides real-time traffic information to traffic management center operators...

Neurobehavioral effects of exposure to traffic-related air pollution and transportation noise in primary schoolchildren.

Science.gov (United States)

van Kempen, Elise; Fischer, Paul; Janssen, Nicole; Houthuijs, Danny; van Kamp, Irene; Stansfeld, Stephen; Cassee, Flemming

2012-05-01

Children living close to roads are exposed to both traffic noise and traffic-related air pollution. There are indications that both exposures affect cognitive functioning. So far, the effects of both exposures have only been investigated separately. To investigate the relationship between air pollution and transportation noise on the cognitive performance of primary schoolchildren in both the home and school setting. Data acquired within RANCH from 553 children (aged 9-11 years) from 24 primary schools were analysed using multilevel modelling with adjustment for a range of socio-economic and life-style factors. Exposure to NO(2) (which is in urban areas an indicator for traffic-related air pollution) at school was statistically significantly associated with a decrease in the memory span length measured during DMST (χ(2)=6.8, df=1, p=0.01). This remained after additional adjustment for transportation noise. Statistically significant associations were observed between road and air traffic noise exposure at school and the number of errors made during the 'arrow' (χ(2)=7.5, df=1, p=0.006) and 'switch' (χ(2)=4.8, df=1, p=0.028) conditions of the SAT. This remained after adjustment for NO(2). No effects of air pollution exposure or transportation noise exposure at home were observed. Combined exposure of air pollution and road traffic noise had a significant effect on the reaction times measured during the SRTT and the 'block' and the 'arrow' conditions of the SAT. Our results provide some support that prolonged exposure to traffic-related air pollution as well as to noise adversely affects cognitive functioning. Copyright © 2012 Elsevier Inc. All rights reserved.

Intelligent Traffic Information System a Real-Time Traffic Information System on the Shiraz Bypass

Directory of Open Access Journals (Sweden)

Sodagaran Amir

2016-01-01

Full Text Available Real-time traffic information system is an Intelligent Transportation System (ITS that allows commuters to make their traveling plan better. In this regard, an intelligent and real-time traffic information system was developed based on the video detection and an image processing algorithm was applied to measure traffic-flow according to the average speed of vehicles. Then, traffic status of each pass way is broadcasted to the electronic boards installed on all decision making entrance / exit. Different levels of congestion related to the routes ahead are shown on the boards with different colors in order to assist commuters. This system was implemented on the Shiraz Dry River’s bypasses which account as vital routes to moderate traffic of city center. Experimental results are promising due to the proximity of determined traffic status by the system compared to the detection done by traffic experts. Average speed improvement is another result of using this system. This intelligent system developed and implemented in Shiraz city for the first time in Iran.s.

Stormwater Management: Calculation of Traffic Area Runoff Loads and Traffic Related Emissions

Directory of Open Access Journals (Sweden)

Maximilian Huber

2016-07-01

Full Text Available Metals such as antimony, cadmium, chromium, copper, lead, nickel, and zinc can be highly relevant pollutants in stormwater runoff from traffic areas because of their occurrence, toxicity, and non-degradability. Long-term measurements of their concentrations, the corresponding water volumes, the catchment areas, and the traffic volumes can be used to calculate specific emission loads and annual runoff loads that are necessary for mass balances. In the literature, the annual runoff loads are often specified by a distinct catchment area (e.g., g/ha. These loads were summarized and discussed in this paper for all seven metals and three types of traffic areas (highways, parking lots, and roads; 45 sites. For example, the calculated median annual runoff loads of all sites are 355 g/ha for copper, 110 g/ha for lead (only data of the 21st century, and 1960 g/ha for zinc. In addition, historical trends, annual variations, and site-specific factors were evaluated for the runoff loads. For Germany, mass balances of traffic related emissions and annual heavy metal runoff loads from highways and total traffic areas were calculated. The influences on the mass fluxes of the heavy metal emissions and the runoff pollution were discussed. However, a statistical analysis of the annual traffic related metal fluxes, in particular for different traffic area categories and land uses, is currently not possible because of a lack of monitoring data.

Synchronized flow in oversaturated city traffic.

Science.gov (United States)

Kerner, Boris S; Klenov, Sergey L; Hermanns, Gerhard; Hemmerle, Peter; Rehborn, Hubert; Schreckenberg, Michael

2013-11-01

Based on numerical simulations with a stochastic three-phase traffic flow model, we reveal that moving queues (moving jams) in oversaturated city traffic dissolve at some distance upstream of the traffic signal while transforming into synchronized flow. It is found that, as in highway traffic [Kerner, Phys. Rev. E 85, 036110 (2012)], such a jam-absorption effect in city traffic is explained by a strong driver's speed adaptation: Time headways (space gaps) between vehicles increase upstream of a moving queue (moving jam), resulting in moving queue dissolution. It turns out that at given traffic signal parameters, the stronger the speed adaptation effect, the shorter the mean distance between the signal location and the road location at which moving queues dissolve fully and oversaturated traffic consists of synchronized flow only. A comparison of the synchronized flow in city traffic found in this Brief Report with synchronized flow in highway traffic is made.

Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic.

Science.gov (United States)

Ryan, Patrick H; LeMasters, Grace; Biagini, Jocelyn; Bernstein, David; Grinshpun, Sergey A; Shukla, Rakesh; Wilson, Kimberly; Villareal, Manuel; Burkle, Jeff; Lockey, James

2005-08-01

Previous studies of air pollution have not examined the association between exposure to varying types, distance, and amounts of traffic and wheezing in very young infants. We sought to determine the relationship between types of traffic, traffic volume, and distance and wheezing among infants less than 1 year of age. A geographic information system and a classification scheme were developed to categorize infants enrolled in the study as living near moving truck and bus traffic (highway >50 miles per hour, >1000 trucks daily, bus traffic (bus and truck traffic had a significantly increased prevalence of wheezing (adjusted odds ratio, 2.50; 95% CI, 1.15-5.42) when compared with unexposed infants. The prevalence of wheezing among nonwhite infants was at least twice that of white infants, regardless of exposure. Infants living less than 400 m from a high volume of moving traffic, however, did not have an increased prevalence of wheezing. These results suggest that the distance from and type of traffic exposures are more significant risk factors than traffic volume for wheezing in early infancy.

A rapid appraisal of traffic policemen about auditory effects of traffic noise pollution from Ambala city

Directory of Open Access Journals (Sweden)

Abhishek Singh

2015-01-01

Full Text Available Context: Traffic policemen are at an increased risk of suffering from hazards of noise pollution because they are engaged in controlling traffic noise, particularly at heavy traffic junctions. The effect is more in this subgroup because they are continuously exposed to it. Aim: The present study was aimed at assessing the knowledge, attitude and practices of traffic policemen regarding auditory effects of traffic noise pollution in Ambala city. Settings and Design: Cross-sectional workplace survey. Materials and Methods: The present descriptive study was carried out in different traffic zones of Ambala city during April-June 2013. The study population consisted of 100 traffic policemen working in different traffic intersections of Ambala city. Statistical Analysis Used: Structured interview schedule was used to collect the data. SPSS version 17.0 was used for analysis. Interpretation of data was performed using percentages and proportions. Results: Majority (75% of the study subjects were exposed to traffic noise pollution for more than 5 years. Of the total subjects, 5% of respondents reported below-average hearing on self-assessment of hearing ability. Seventeen percent of the study population accepted that while hearing over phone they do miss some conversation. Most (98% of the traffic police did not use any personal protective equipment (PPEs like earplugs/earmuffs, and the non-availability of these PPEs (90% is the common reason for the hearing loss. Conclusions: The study concludes that traffic policemen are not much aware regarding impending auditory effects of traffic noise pollution. Duty rotation, duty scheduling and other forms of preventive modalities for exposure limitation are suggested.

Road Traffic Injuries

Institute of Scientific and Technical Information of China (English)

WANG Zheng-guo

2005-01-01

@@ As everybody knows that automobiles have been greatly changing our life. However, everything has two sides, motor vehicles have also caused a huge number of people's deaths, injuries and property damage. Traffic crashes are perhaps the number one public health problem in developed countries [1]. In the United States, pre-retirement years of life lost in traffic crashes are more than that of the two combined leading diseases: cancer and heart disease [1]. Today road traffic crash (RTC) ranks 11th in leading cause of death and accounts for 2.1% of all deaths globally.

Packet traffic features of IPv6 and IPv4 protocol traffic

OpenAIRE

ÇİFLİKLİ, Cebrail; GEZER, Ali; ÖZŞAHİN, Abdullah Tuncay

2012-01-01

Nowadays, the IPv6 protocol is in a transition phase in operational networks. The ratio of its traffic volume is increasing day by day. The many provided facilities for IPv6 connection increasethe total IPv6 traffic load. IPv6-over-IPv4 tunnels, pilot programsto provide IPv6 connections, IPv6/IPv4 dual stack operating systems,and free IPv6 tunnel brokers cause the IPv6 protocol to expand quickly. For efficient resource utilization, the characteristics of network traffic should be determ...

Urban Road Traffic Simulation Techniques

Directory of Open Access Journals (Sweden)

Ana Maria Nicoleta Mocofan

2011-09-01

Full Text Available For achieving a reliable traffic control system it is necessary to first establish a network parameter evaluation system and also a simulation system for the traffic lights plan. In 40 years of history, the computer aided traffic simulation has developed from a small research group to a large scale technology for traffic systems planning and development. In the following thesis, a presentation of the main modeling and simulation road traffic applications will be provided, along with their utility, as well as the practical application of one of the models in a case study.

Traffic Flow Management Wrap-Up

Science.gov (United States)

Grabbe, Shon

2011-01-01

Traffic Flow Management involves the scheduling and routing of air traffic subject to airport and airspace capacity constraints, and the efficient use of available airspace. Significant challenges in this area include: (1) weather integration and forecasting, (2) accounting for user preferences in the Traffic Flow Management decision making process, and (3) understanding and mitigating the environmental impacts of air traffic on the environment. To address these challenges, researchers in the Traffic Flow Management area are developing modeling, simulation and optimization techniques to route and schedule air traffic flights and flows while accommodating user preferences, accounting for system uncertainties and considering the environmental impacts of aviation. This presentation will highlight some of the major challenges facing researchers in this domain, while also showcasing recent innovations designed to address these challenges.

Monitoring road traffic congestion using a macroscopic traffic model and a statistical monitoring scheme

KAUST Repository

Zeroual, Abdelhafid; Harrou, Fouzi; Sun, Ying; Messai, Nadhir

2017-01-01

Monitoring vehicle traffic flow plays a central role in enhancing traffic management, transportation safety and cost savings. In this paper, we propose an innovative approach for detection of traffic congestion. Specifically, we combine the flexibility and simplicity of a piecewise switched linear (PWSL) macroscopic traffic model and the greater capacity of the exponentially-weighted moving average (EWMA) monitoring chart. Macroscopic models, which have few, easily calibrated parameters, are employed to describe a free traffic flow at the macroscopic level. Then, we apply the EWMA monitoring chart to the uncorrelated residuals obtained from the constructed PWSL model to detect congested situations. In this strategy, wavelet-based multiscale filtering of data has been used before the application of the EWMA scheme to improve further the robustness of this method to measurement noise and reduce the false alarms due to modeling errors. The performance of the PWSL-EWMA approach is successfully tested on traffic data from the three lane highway portion of the Interstate 210 (I-210) highway of the west of California and the four lane highway portion of the State Route 60 (SR60) highway from the east of California, provided by the Caltrans Performance Measurement System (PeMS). Results show the ability of the PWSL-EWMA approach to monitor vehicle traffic, confirming the promising application of this statistical tool to the supervision of traffic flow congestion.

Monitoring road traffic congestion using a macroscopic traffic model and a statistical monitoring scheme

KAUST Repository

Zeroual, Abdelhafid

2017-08-19

Monitoring vehicle traffic flow plays a central role in enhancing traffic management, transportation safety and cost savings. In this paper, we propose an innovative approach for detection of traffic congestion. Specifically, we combine the flexibility and simplicity of a piecewise switched linear (PWSL) macroscopic traffic model and the greater capacity of the exponentially-weighted moving average (EWMA) monitoring chart. Macroscopic models, which have few, easily calibrated parameters, are employed to describe a free traffic flow at the macroscopic level. Then, we apply the EWMA monitoring chart to the uncorrelated residuals obtained from the constructed PWSL model to detect congested situations. In this strategy, wavelet-based multiscale filtering of data has been used before the application of the EWMA scheme to improve further the robustness of this method to measurement noise and reduce the false alarms due to modeling errors. The performance of the PWSL-EWMA approach is successfully tested on traffic data from the three lane highway portion of the Interstate 210 (I-210) highway of the west of California and the four lane highway portion of the State Route 60 (SR60) highway from the east of California, provided by the Caltrans Performance Measurement System (PeMS). Results show the ability of the PWSL-EWMA approach to monitor vehicle traffic, confirming the promising application of this statistical tool to the supervision of traffic flow congestion.

Pedestrian Friendly Traffic Signal Control.

Science.gov (United States)

2016-01-01

This project continues research aimed at real-time detection and use of pedestrian : traffic flow information to enhance adaptive traffic signal control in urban areas : where pedestrian traffic is substantial and must be given appropriate attention ...

Costs of traffic injuries

DEFF Research Database (Denmark)

Kruse, Marie

2015-01-01

assessed using Danish national healthcare registers. Productivity costs were computed using duration analysis (Cox regression models). In a subanalysis, cost per severe traffic injury was computed for the 12 995 individuals that experienced a severe injury. RESULTS: The socioeconomic cost of a traffic...... injury was €1406 (2009 price level) in the first year, and €8950 over a 10-year period. Per 100 000 population, the 10-year cost was €6 565 668. A severe traffic injury costs €4969 per person in the first year, and €4 006 685 per 100 000 population over a 10-year period. Victims of traffic injuries...

Traffic simulation for mixed traffic systems | Mbam | Global Journal of ...

African Journals Online (AJOL)

Traffic problem is classified into single and mixed, especially in most developing countries, where motorbikes are used as the most popular transportation system. The aim of this paper is to introduce the motorbike symbol into the traffic light control system to separate cars/lorries indicator from that of motorbike. This is likely ...

Traffic information computing platform for big data

Energy Technology Data Exchange (ETDEWEB)

Duan, Zongtao, E-mail: ztduan@chd.edu.cn; Li, Ying, E-mail: ztduan@chd.edu.cn; Zheng, Xibin, E-mail: ztduan@chd.edu.cn; Liu, Yan, E-mail: ztduan@chd.edu.cn; Dai, Jiting, E-mail: ztduan@chd.edu.cn; Kang, Jun, E-mail: ztduan@chd.edu.cn [Chang' an University School of Information Engineering, Xi' an, China and Shaanxi Engineering and Technical Research Center for Road and Traffic Detection, Xi' an (China)

2014-10-06

Big data environment create data conditions for improving the quality of traffic information service. The target of this article is to construct a traffic information computing platform for big data environment. Through in-depth analysis the connotation and technology characteristics of big data and traffic information service, a distributed traffic atomic information computing platform architecture is proposed. Under the big data environment, this type of traffic atomic information computing architecture helps to guarantee the traffic safety and efficient operation, more intelligent and personalized traffic information service can be used for the traffic information users.

Traffic information computing platform for big data

International Nuclear Information System (INIS)

Duan, Zongtao; Li, Ying; Zheng, Xibin; Liu, Yan; Dai, Jiting; Kang, Jun

2014-01-01

Big data environment create data conditions for improving the quality of traffic information service. The target of this article is to construct a traffic information computing platform for big data environment. Through in-depth analysis the connotation and technology characteristics of big data and traffic information service, a distributed traffic atomic information computing platform architecture is proposed. Under the big data environment, this type of traffic atomic information computing architecture helps to guarantee the traffic safety and efficient operation, more intelligent and personalized traffic information service can be used for the traffic information users

Traffic forecasts ignoring induced demand

DEFF Research Database (Denmark)

Næss, Petter; Nicolaisen, Morten Skou; Strand, Arvid

2012-01-01

the model calculations included only a part of the induced traffic, the difference in cost-benefit results compared to the model excluding all induced traffic was substantial. The results show lower travel time savings, more adverse environmental impacts and a considerably lower benefitcost ratio when...... induced traffic is partly accounted for than when it is ignored. By exaggerating the economic benefits of road capacity increase and underestimating its negative effects, omission of induced traffic can result in over-allocation of public money on road construction and correspondingly less focus on other...... performance of a proposed road project in Copenhagen with and without short-term induced traffic included in the transport model. The available transport model was not able to include long-term induced traffic resulting from changes in land use and in the level of service of public transport. Even though...

Traffic intensity monitoring using multiple object detection with traffic surveillance cameras

Science.gov (United States)

Hamdan, H. G. Muhammad; Khalifah, O. O.

2017-11-01

Object detection and tracking is a field of research that has many applications in the current generation with increasing number of cameras on the streets and lower cost for Internet of Things(IoT). In this paper, a traffic intensity monitoring system is implemented based on the Macroscopic Urban Traffic model is proposed using computer vision as its source. The input of this program is extracted from a traffic surveillance camera which has another program running a neural network classification which can identify and differentiate the vehicle type is implanted. The neural network toolbox is trained with positive and negative input to increase accuracy. The accuracy of the program is compared to other related works done and the trends of the traffic intensity from a road is also calculated. relevant articles in literature searches, great care should be taken in constructing both. Lastly the limitation and the future work is concluded.

Intelligent Traffic Light Based on PLC Control

Science.gov (United States)

Mei, Lin; Zhang, Lijian; Wang, Lingling

2017-11-01

The traditional traffic light system with a fixed control mode and single control function is contradicted with the current traffic section. The traditional one has been unable to meet the functional requirements of the existing flexible traffic control system. This paper research and develop an intelligent traffic light called PLC control system. It uses PLC as control core, using a sensor module for receiving real-time information of vehicles, traffic control mode for information to select the traffic lights. Of which control mode is flexible and changeable, and it also set the countdown reminder to improve the effectiveness of traffic lights, which can realize the goal of intelligent traffic diversion, intelligent traffic diversion.

ITSA: Internet Traffic Statistics Archive

NARCIS (Netherlands)

Hoogesteger, Martijn; de Oliveira Schmidt, R.; Pras, Aiko

Motivated by the fact that comprehensive and long term Internet traffic measurements can be hard to obtain, we have proposed and developed the Internet Traffic Statistics Archive (ITSA). Since 2013, ITSA concentrates reports on high-level statistics of Internet traffic worldwide. Examples of

Fuzzy Multiobjective Traffic Light Signal Optimization

Directory of Open Access Journals (Sweden)

N. Shahsavari Pour

2013-01-01

Full Text Available Traffic congestion is a major concern for many cities throughout the world. In a general traffic light controller, the traffic lights change at a constant cycle time. Hence it does not provide an optimal solution. Many traffic light controllers in current use are based on the “time-of-the-day” scheme, which use a limited number of predetermined traffic light patterns and implement these patterns depending upon the time of the day. These automated systems do not provide an optimal control for fluctuating traffic volumes. In this paper, the fuzzy traffic light controller is used to optimize the control of fluctuating traffic volumes such as oversaturated or unusual load conditions. The problem is solved by genetic algorithm, and a new defuzzification method is introduced. The performance of the new defuzzification method (NDM is compared with the centroid point defuzzification method (CPDM by using ANOVA. Finally, an illustrative example is presented to show the competency of proposed algorithm.

Traffic Management as a Service: The Traffic Flow Pattern Classification Problem

Directory of Open Access Journals (Sweden)

Carlos T. Calafate

2015-01-01

Full Text Available Intelligent Transportation System (ITS technologies can be implemented to reduce both fuel consumption and the associated emission of greenhouse gases. However, such systems require intelligent and effective route planning solutions to reduce travel time and promote stable traveling speeds. To achieve such goal these systems should account for both estimated and real-time traffic congestion states, but obtaining reliable traffic congestion estimations for all the streets/avenues in a city for the different times of the day, for every day in a year, is a complex task. Modeling such a tremendous amount of data can be time-consuming and, additionally, centralized computation of optimal routes based on such time-dependencies has very high data processing requirements. In this paper we approach this problem through a heuristic to considerably reduce the modeling effort while maintaining the benefits of time-dependent traffic congestion modeling. In particular, we propose grouping streets by taking into account real traces describing the daily traffic pattern. The effectiveness of this heuristic is assessed for the city of Valencia, Spain, and the results obtained show that it is possible to reduce the required number of daily traffic flow patterns by a factor of 4210 while maintaining the essence of time-dependent modeling requirements.

Endocytic pathways involved in PLGA nanoparticle uptake by grapevine cells and role of cell wall and membrane in size selection.

Science.gov (United States)

Palocci, Cleofe; Valletta, Alessio; Chronopoulou, Laura; Donati, Livia; Bramosanti, Marco; Brasili, Elisa; Baldan, Barbara; Pasqua, Gabriella

2017-12-01

PLGA NPs' cell uptake involves different endocytic pathways. Clathrin-independent endocytosis is the main internalization route. The cell wall plays a more prominent role than the plasma membrane in NPs' size selection. In the last years, many studies on absorption and cell uptake of nanoparticles by plants have been conducted, but the understanding of the internalization mechanisms is still largely unknown. In this study, polydispersed and monodispersed poly(lactic-co-glycolic) acid nanoparticles (PLGA NPs) were synthesized, and a strategy combining the use of transmission electron microscopy (TEM), confocal analysis, fluorescently labeled PLGA NPs, a probe for endocytic vesicles (FM4-64), and endocytosis inhibitors (i.e., wortmannin, ikarugamycin, and salicylic acid) was employed to shed light on PLGA NP cell uptake in grapevine cultured cells and to assess the role of the cell wall and plasma membrane in size selection of PLGA NPs. The ability of PLGA NPs to cross the cell wall and membrane was confirmed by TEM and fluorescence microscopy. A strong adhesion of PLGA NPs to the outer side of the cell wall was observed, presumably due to electrostatic interactions. Confocal microscopy and treatment with endocytosis inhibitors suggested the involvement of both clathrin-dependent and clathrin-independent endocytosis in cell uptake of PLGA NPs and the latter appeared to be the main internalization pathway. Experiments on grapevine protoplasts revealed that the cell wall plays a more prominent role than the plasma membrane in size selection of PLGA NPs. While the cell wall prevents the uptake of PLGA NPs with diameters over 50 nm, the plasma membrane can be crossed by PLGA NPs with a diameter of 500-600 nm.

Lagrangian Multi-Class Traffic State Estimation

NARCIS (Netherlands)

Yuan, Y.

2013-01-01

Road traffic is important to everybody in the world. People travel and commute everyday. For those who travel by cars (or other types of road vehicles), traffic congestion is a daily experience. One essential goal of traffic researchers is to reduce traffic congestion and to improve the whole

Traffic analysis toolbox volume XI : weather and traffic analysis, modeling and simulation.

Science.gov (United States)

2010-12-01

This document presents a weather module for the traffic analysis tools program. It provides traffic engineers, transportation modelers and decisions makers with a guide that can incorporate weather impacts into transportation system analysis and mode...

State Traffic Safety Information

Data.gov (United States)

Department of Transportation — The State Traffic Safety Information (STSI) portal is part of the larger Fatality Analysis Reporting System (FARS) Encyclopedia. STSI provides state-by-state traffic...

Traffic Agents for Improving QoS in Mixed Infrastructure and Ad Hoc Modes Wireless LAN

Directory of Open Access Journals (Sweden)

Yuan Hai-Feng

2006-01-01

Full Text Available As an important complement to infrastructured wireless networks, mobile ad hoc networks (MANET are more flexible in providing wireless access services, but more difficult in meeting different quality of service (QoS requirements for mobile customers. Both infrastructure and ad hoc network structures are supported in wireless local area networks (WLAN, which can offer high data-rate wireless multimedia services to the mobile stations (MSs in a limited geographical area. For those out-of-coverage MSs, how to effectively connect them to the access point (AP and provide QoS support is a challenging issue. By mixing the infrastructure and the ad hoc modes in WLAN, we propose in this paper a new coverage improvement scheme that can identify suitable idle MSs in good service zones as traffic agents (TAs to relay traffic from those out-of-coverage MSs to the AP. The service coverage area of WLAN is then expanded. The QoS requirements (e.g., bandwidth of those MSs are considered in the selection process of corresponding TAs. Mathematical analysis, verified by computer simulations, shows that the proposed TA scheme can effectively reduce blocking probability when traffic load is light.

Dynamic control of traffic lights

NARCIS (Netherlands)

Haijema, Rene; Hendrix, Eligius M.T.; Wal, van der Jan

2017-01-01

Traffic lights are put in place to dynamically change priority between traffic participants. Commonly, the duration of green intervals and the grouping, and ordering in which traffic flows are served are pre-fixed. In this chapter, the problem of minimizing vehicle delay at isolated intersections is

Consensus-Based Cooperative Control Based on Pollution Sensing and Traffic Information for Urban Traffic Networks.

Science.gov (United States)

Artuñedo, Antonio; Del Toro, Raúl M; Haber, Rodolfo E

2017-04-26

Nowadays many studies are being conducted to develop solutions for improving the performance of urban traffic networks. One of the main challenges is the necessary cooperation among different entities such as vehicles or infrastructure systems and how to exploit the information available through networks of sensors deployed as infrastructures for smart cities. In this work an algorithm for cooperative control of urban subsystems is proposed to provide a solution for mobility problems in cities. The interconnected traffic lights controller ( TLC ) network adapts traffic lights cycles, based on traffic and air pollution sensory information, in order to improve the performance of urban traffic networks. The presence of air pollution in cities is not only caused by road traffic but there are other pollution sources that contribute to increase or decrease the pollution level. Due to the distributed and heterogeneous nature of the different components involved, a system of systems engineering approach is applied to design a consensus-based control algorithm. The designed control strategy contains a consensus-based component that uses the information shared in the network for reaching a consensus in the state of TLC network components. Discrete event systems specification is applied for modelling and simulation. The proposed solution is assessed by simulation studies with very promising results to deal with simultaneous responses to both pollution levels and traffic flows in urban traffic networks.

Consensus-Based Cooperative Control Based on Pollution Sensing and Traffic Information for Urban Traffic Networks

Directory of Open Access Journals (Sweden)

Antonio Artuñedo

2017-04-01

Full Text Available Nowadays many studies are being conducted to develop solutions for improving the performance of urban traffic networks. One of the main challenges is the necessary cooperation among different entities such as vehicles or infrastructure systems and how to exploit the information available through networks of sensors deployed as infrastructures for smart cities. In this work an algorithm for cooperative control of urban subsystems is proposed to provide a solution for mobility problems in cities. The interconnected traffic lights controller (TLC network adapts traffic lights cycles, based on traffic and air pollution sensory information, in order to improve the performance of urban traffic networks. The presence of air pollution in cities is not only caused by road traffic but there are other pollution sources that contribute to increase or decrease the pollution level. Due to the distributed and heterogeneous nature of the different components involved, a system of systems engineering approach is applied to design a consensus-based control algorithm. The designed control strategy contains a consensus-based component that uses the information shared in the network for reaching a consensus in the state of TLC network components. Discrete event systems specification is applied for modelling and simulation. The proposed solution is assessed by simulation studies with very promising results to deal with simultaneous responses to both pollution levels and traffic flows in urban traffic networks.

Dynamic Traffic Congestion Simulation and Dissipation Control Based on Traffic Flow Theory Model and Neural Network Data Calibration Algorithm

Directory of Open Access Journals (Sweden)

Li Wang

2017-01-01

Full Text Available Traffic congestion is a common problem in many countries, especially in big cities. At present, China’s urban road traffic accidents occur frequently, the occurrence frequency is high, the accident causes traffic congestion, and accidents cause traffic congestion and vice versa. The occurrence of traffic accidents usually leads to the reduction of road traffic capacity and the formation of traffic bottlenecks, causing the traffic congestion. In this paper, the formation and propagation of traffic congestion are simulated by using the improved medium traffic model, and the control strategy of congestion dissipation is studied. From the point of view of quantitative traffic congestion, the paper provides the fact that the simulation platform of urban traffic integration is constructed, and a feasible data analysis, learning, and parameter calibration method based on RBF neural network is proposed, which is used to determine the corresponding decision support system. The simulation results prove that the control strategy proposed in this paper is effective and feasible. According to the temporal and spatial evolution of the paper, we can see that the network has been improved on the whole.

A Partial Proportional Odds Model for Pedestrian Crashes at Mid-Blocks in Melbourne Metropolitan Area

Directory of Open Access Journals (Sweden)

Toran Pour Alireza

2016-01-01

Full Text Available Pedestrian crashes account for 11% of all reported traffic crashes in Melbourne metropolitan area between 2004 and 2013. There are very limited studies on pedestrian accidents at mid-blocks. Mid-block crashes account for about 46% of the total pedestrian crashes in Melbourne metropolitan area. Meanwhile, about 50% of all pedestrian fatalities occur at mid-blocks. In this research, Partial Proportional Odds (PPO model is applied to examine vehicle-pedestrian crash severity at mid-blocks in Melbourne metropolitan area. The PPO model is a logistic regression model that allows the covariates that meet the proportional odds assumption to affect different crash severity levels with the same magnitude; whereas the covariates that do not meet the proportional odds assumption can have different effects on different severity levels. In this research vehicle-pedestrian crashes at mid-blocks are analysed for first time. In addition, some factors such as distance of crashes to public transport stops, average road slope and some social characteristics are considered to develop the model in this research for first time. Results of PPO model show that speed limit, light condition, pedestrian age and gender, and vehicle type are the most significant factors that influence vehicle-pedestrian crash severity at mid-blocks.

Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue.

Science.gov (United States)

Morris, Christopher J; Aljayyoussi, Ghaith; Mansour, Omar; Griffiths, Peter; Gumbleton, Mark

2017-12-01

Polyamidoamine (PAMAM) dendrimers are a promising class of nanocarrier with applications in both small and large molecule drug delivery. Here we report a comprehensive evaluation of the uptake and transport pathways that contribute to the lung disposition of dendrimers. Anionic PAMAM dendrimers and control dextran probes were applied to an isolated perfused rat lung (IPRL) model and lung epithelial monolayers. Endocytosis pathways were examined in primary alveolar epithelial cultures by confocal microscopy. Molecular interactions of dendrimers with protein and lipid lung fluid components were studied using small angle neutron scattering (SANS). Dendrimers were absorbed across the intact lung via a passive, size-dependent transport pathway at rates slower than dextrans of similar molecular sizes. SANS investigations of concentration-dependent PAMAM transport in the IPRL confirmed no aggregation of PAMAMs with either albumin or dipalmitoylphosphatidylcholine lung lining fluid components. Distinct endocytic compartments were identified within primary alveolar epithelial cells and their functionality in the rapid uptake of fluorescent dendrimers and model macromolecular probes was confirmed by co-localisation studies. PAMAM dendrimers display favourable lung biocompatibility but modest lung to blood absorption kinetics. These data support the investigation of dendrimer-based carriers for controlled-release drug delivery to the deep lung.

Framework for Traffic Congestion Prediction

NARCIS (Netherlands)

Zaki, J.F.W.; Ali-Eldin, A.M.T.; Hussein, S.E.; Saraya, S.F.; Areed, F.F.

2016-01-01

Traffic Congestion is a complex dilemma facing most major cities. It has undergone a lot of research since the early 80s in an attempt to predict traffic in the short-term. Recently, Intelligent Transportation Systems (ITS) became an integral part of traffic research which helped in modeling and

Traffic sign detection and analysis

DEFF Research Database (Denmark)

Møgelmose, Andreas; Trivedi, Mohan M.; Moeslund, Thomas B.

2012-01-01

Traffic sign recognition (TSR) is a research field that has seen much activity in the recent decade. This paper introduces the problem and presents 4 recent papers on traffic sign detection and 4 recent papers on traffic sign classification. It attempts to extract recent trends in the field...

Forecasting Multivariate Road Traffic Flows Using Bayesian Dynamic Graphical Models, Splines and Other Traffic Variables

NARCIS (Netherlands)

Anacleto, Osvaldo; Queen, Catriona; Albers, Casper J.

Traffic flow data are routinely collected for many networks worldwide. These invariably large data sets can be used as part of a traffic management system, for which good traffic flow forecasting models are crucial. The linear multiregression dynamic model (LMDM) has been shown to be promising for

Air traffic control activity increases attention capacity in air traffic controllers.

Science.gov (United States)

Ribas, Valdenilson Ribeiro; Martins, Hugo André de Lima; Amorim, Gutemberg Guerra; Ribas, Renata de Melo Guerra; de Almeida, Cláudia Ângela Vilela; Ribas, Valéria Ribeiro; de Vasconcelos, Carlos Augusto Carvalho; Lima, Murilo Duarte Costa; Sougey, Everton Botelho; de Castro, Raul Manhães

2010-01-01

Air traffic controllers simultaneously develop complex and multiple tasks in the course of their activities. In this context, concern is raised over the high level of attention needed by these professionals which can ultimately be affected by stress and fatigue. The objective of this study was to assess attention level in air traffic controllers (ATCo). 45 flight protection professionals were evaluated, comprising 30 ATCo, subdivided into ATCo with ten or more years in the profession (ATCo≥10, n=15) and ATCo with less than ten years in the profession (ATCo air traffic control activity after ten years may be associated with a high level of attention.

Traffic and Granular Flow ’07

CERN Document Server

Chevoir, François; Gondret, Philippe; Lassarre, Sylvain; Lebacque, Jean-Patrick; Schreckenberg, Michael

2009-01-01

This book covers several research fields, all of which deal with transport. Three main topics are treated: road traffic, granular matter, and biological transport. Different points of view, i.e. modelling, simulations, experiments, and phenomenological observations, are considered. Sub-topics include: highway or urban vehicular traffic (dynamics of traffic, macro/micro modelling, measurements, data analysis, security issues, psychological issues), pedestrian traffic, animal traffic (e.g. social insects), collective motion in biological systems (molecular motors...), granular flow (dense flows, intermittent flows, solid/liquid transition, jamming, force networks, fluid and solid friction), networks (biological networks, urban traffic, the internet, vulnerability of networks, optimal transport networks) and cellular automata applied to the various aforementioned fields.

32 CFR 634.32 - Traffic violation reports.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Traffic violation reports. 634.32 Section 634.32 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.32 Traffic violation reports. (a) Most traffic violations...

Probabilistic description of traffic flow

International Nuclear Information System (INIS)

Mahnke, R.; Kaupuzs, J.; Lubashevsky, I.

2005-01-01

A stochastic description of traffic flow, called probabilistic traffic flow theory, is developed. The general master equation is applied to relatively simple models to describe the formation and dissolution of traffic congestions. Our approach is mainly based on spatially homogeneous systems like periodically closed circular rings without on- and off-ramps. We consider a stochastic one-step process of growth or shrinkage of a car cluster (jam). As generalization we discuss the coexistence of several car clusters of different sizes. The basic problem is to find a physically motivated ansatz for the transition rates of the attachment and detachment of individual cars to a car cluster consistent with the empirical observations in real traffic. The emphasis is put on the analogy with first-order phase transitions and nucleation phenomena in physical systems like supersaturated vapour. The results are summarized in the flux-density relation, the so-called fundamental diagram of traffic flow, and compared with empirical data. Different regimes of traffic flow are discussed: free flow, congested mode as stop-and-go regime, and heavy viscous traffic. The traffic breakdown is studied based on the master equation as well as the Fokker-Planck approximation to calculate mean first passage times or escape rates. Generalizations are developed to allow for on-ramp effects. The calculated flux-density relation and characteristic breakdown times coincide with empirical data measured on highways. Finally, a brief summary of the stochastic cellular automata approach is given

Traffic Flow Prediction Using MI Algorithm and Considering Noisy and Data Loss Conditions: An Application to Minnesota Traffic Flow Prediction

Directory of Open Access Journals (Sweden)

Seyed Hadi Hosseini

2014-10-01

Full Text Available Traffic flow forecasting is useful for controlling traffic flow, traffic lights, and travel times. This study uses a multi-layer perceptron neural network and the mutual information (MI technique to forecast traffic flow and compares the prediction results with conventional traffic flow forecasting methods. The MI method is used to calculate the interdependency of historical traffic data and future traffic flow. In numerical case studies, the proposed traffic flow forecasting method was tested against data loss, changes in weather conditions, traffic congestion, and accidents. The outcomes were highly acceptable for all cases and showed the robustness of the proposed flow forecasting method.

Probiotics promote endocytic allergen degradation in gut epithelial cells

International Nuclear Information System (INIS)

Song, Chun-Hua; Liu, Zhi-Qiang; Huang, Shelly; Zheng, Peng-Yuan; Yang, Ping-Chang

2012-01-01

Highlights: ► Knockdown of A20 compromised the epithelial barrier function. ► The fusion of endosome/lysosome was disturbed in the A20-deficient HT-29 cells. ► Antigens transported across A20-deficient HT-29 monolayers conserved antigenicity. ► Probiotic proteins increased the expression of A20 in HT-29 cells. -- Abstract: Background and aims: Epithelial barrier dysfunction plays a critical role in the pathogenesis of allergic diseases; the mechanism is to be further understood. The ubiquitin E3 ligase A20 (A20) plays a role in the endocytic protein degradation in the cells. This study aims to elucidate the role of A20 in the maintenance of gut epithelial barrier function. Methods: Gut epithelial cell line, HT-29 cell, was cultured into monolayers to evaluate the barrier function in transwells. RNA interference was employed to knock down the A20 gene in HT-29 cells to test the role of A20 in the maintenance of epithelial barrier function. Probiotic derived proteins were extracted from the culture supernatants using to enhance the expression of A20 in HT-29 cells. Results: The results showed that the knockdown of A20 compromised the epithelial barrier function in HT-29 monolayers, mainly increased the intracellular permeability. The fusion of endosome/lysosome was disturbed in the A20-deficient HT-29 cells. Allergens collected from the transwell basal chambers of A20-deficient HT-29 monolayers still conserved functional antigenicity. Treating with probiotic derived proteins increased the expression of A20 in HT-29 cells and promote the barrier function. Conclusion: A20 plays an important role in the maintenance of epithelial barrier function as shown by HT-29 monolayer. Probiotic derived protein increases the expression of A20 and promote the HT-29 monolayer barrier function.

Probiotics promote endocytic allergen degradation in gut epithelial cells

Energy Technology Data Exchange (ETDEWEB)

Song, Chun-Hua [Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou (China); Liu, Zhi-Qiang [Department of Gastroenterology, The Second Hospital, Zhengzhou University, Zhengzhou (China); Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON (Canada); Huang, Shelly [Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON (Canada); Zheng, Peng-Yuan, E-mail: medp7123@126.com [Department of Gastroenterology, The Second Hospital, Zhengzhou University, Zhengzhou (China); Yang, Ping-Chang, E-mail: yangp@mcmaster.ca [Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON (Canada)

2012-09-14

Highlights: Black-Right-Pointing-Pointer Knockdown of A20 compromised the epithelial barrier function. Black-Right-Pointing-Pointer The fusion of endosome/lysosome was disturbed in the A20-deficient HT-29 cells. Black-Right-Pointing-Pointer Antigens transported across A20-deficient HT-29 monolayers conserved antigenicity. Black-Right-Pointing-Pointer Probiotic proteins increased the expression of A20 in HT-29 cells. -- Abstract: Background and aims: Epithelial barrier dysfunction plays a critical role in the pathogenesis of allergic diseases; the mechanism is to be further understood. The ubiquitin E3 ligase A20 (A20) plays a role in the endocytic protein degradation in the cells. This study aims to elucidate the role of A20 in the maintenance of gut epithelial barrier function. Methods: Gut epithelial cell line, HT-29 cell, was cultured into monolayers to evaluate the barrier function in transwells. RNA interference was employed to knock down the A20 gene in HT-29 cells to test the role of A20 in the maintenance of epithelial barrier function. Probiotic derived proteins were extracted from the culture supernatants using to enhance the expression of A20 in HT-29 cells. Results: The results showed that the knockdown of A20 compromised the epithelial barrier function in HT-29 monolayers, mainly increased the intracellular permeability. The fusion of endosome/lysosome was disturbed in the A20-deficient HT-29 cells. Allergens collected from the transwell basal chambers of A20-deficient HT-29 monolayers still conserved functional antigenicity. Treating with probiotic derived proteins increased the expression of A20 in HT-29 cells and promote the barrier function. Conclusion: A20 plays an important role in the maintenance of epithelial barrier function as shown by HT-29 monolayer. Probiotic derived protein increases the expression of A20 and promote the HT-29 monolayer barrier function.

Framework for Traffic Congestion Management

Directory of Open Access Journals (Sweden)

Mahmud Hassan TALUKDAR

2013-06-01

Full Text Available Traffic Congestion is one of many serious global problems in all great cities resulted from rapid urbanization which always exert negative externalities upon society. The solution of traffic congestion is highly geocentric and due to its heterogeneous nature, curbing congestion is one of the hard tasks for transport planners. It is not possible to suggest unique traffic congestion management framework which could be absolutely applied for every great cities. Conversely, it is quite feasible to develop a framework which could be used with or without minor adjustment to deal with congestion problem. So, the main aim of this paper is to prepare a traffic congestion mitigation framework which will be useful for urban planners, transport planners, civil engineers, transport policy makers, congestion management researchers who are directly or indirectly involved or willing to involve in the task of traffic congestion management. Literature review is the main source of information of this study. In this paper, firstly, traffic congestion is defined on the theoretical point of view and then the causes of traffic congestion are briefly described. After describing the causes, common management measures, using world- wide, are described and framework for supply side and demand side congestion management measures are prepared.

Emergent traffic jams

International Nuclear Information System (INIS)

Nagel, K.; Paczuski, M.

1995-01-01

We study a single-lane traffic model that is based on human driving behavior. The outflow from a traffic jam self-organizes to a critical state of maximum throughput. Small perturbations of the outflow far downstream create emergent traffic jams with a power law distribution P(t)∼t -3/2 of lifetimes t. On varying the vehicle density in a closed system, this critical state separates lamellar and jammed regimes and exhibits 1/f noise in the power spectrum. Using random walk arguments, in conjunction with a cascade equation, we develop a phenomenological theory that predicts the critical exponents for this transition and explains the self-organizing behavior. These predictions are consistent with all of our numerical results

Emergent traffic jams

Science.gov (United States)

Nagel, Kai; Paczuski, Maya

1995-04-01

We study a single-lane traffic model that is based on human driving behavior. The outflow from a traffic jam self-organizes to a critical state of maximum throughput. Small perturbations of the outflow far downstream create emergent traffic jams with a power law distribution P(t)~t-3/2 of lifetimes t. On varying the vehicle density in a closed system, this critical state separates lamellar and jammed regimes and exhibits 1/f noise in the power spectrum. Using random walk arguments, in conjunction with a cascade equation, we develop a phenomenological theory that predicts the critical exponents for this transition and explains the self-organizing behavior. These predictions are consistent with all of our numerical results.

Simulation of traffic control signal systems

Science.gov (United States)

Connolly, P. J.; Concannon, P. A.; Ricci, R. C.

1974-01-01

In recent years there has been considerable interest in the development and testing of control strategies for networks of urban traffic signal systems by simulation. Simulation is an inexpensive and timely method for evaluating the effect of these traffic control strategies since traffic phenomena are too complex to be defined by analytical models and since a controlled experiment may be hazardous, expensive, and slow in producing meaningful results. This paper describes the application of an urban traffic corridor program, to evaluate the effectiveness of different traffic control strategies for the Massachusetts Avenue TOPICS Project.

[Comics for traffic education: evaluation of a traffic safety campaign].

Science.gov (United States)

Bonfadelli, H

1989-01-01

Traffic safety campaigns often are ineffective to change driving behavior because they don't reach the target group or are recognized only by people who are already interested or concerned. The evaluation of a traffic safety campaign called "Leo Lässig", addressed to young new drivers, shows that recognition and acceptance by the target group were stimulated by the age-conform means of comic-strips.

Impact Analysis of Land Use on Traffic Congestion Using Real-Time Traffic and POI

Directory of Open Access Journals (Sweden)

Tianqi Zhang

2017-01-01

Full Text Available This paper proposed a new method to describe, compare, and classify the traffic congestion points in Beijing, China, by using the online map data and further revealed the relationship between traffic congestion and land use. The data of the point of interest (POI and the real-time traffic was extracted from an electronic map of the area in the fourth ring road of Beijing. The POIs were quantified based on the architectural area of the land use; the congestion points were identified based on real-time traffic. Then, the cluster analysis using the attributes of congestion time was conducted to identify the main traffic congestion areas. The result of a linear regression analysis between the congestion time and the land use showed that the influence of the high proportion of commercial land use on the traffic congestion was significant. Also, we considered five types of land use through performing a linear regression analysis between the congestion time and the ratio of four types of land use. The results showed that the reasonable ratio of land use types could efficiently reduce congestion time. This study makes contributions to the policy-making of urban land use.

Remotely Accessed Vehicle Traffic Management System

Science.gov (United States)

Al-Alawi, Raida

2010-06-01

The ever increasing number of vehicles in most metropolitan cities around the world and the limitation in altering the transportation infrastructure, led to serious traffic congestion and an increase in the travelling time. In this work we exploit the emergence of novel technologies such as the internet, to design an intelligent Traffic Management System (TMS) that can remotely monitor and control a network of traffic light controllers located at different sites. The system is based on utilizing Embedded Web Servers (EWS) technology to design a web-based TMS. The EWS located at each intersection uses IP technology for communicating remotely with a Central Traffic Management Unit (CTMU) located at the traffic department authority. Friendly GUI software installed at the CTMU will be able to monitor the sequence of operation of the traffic lights and the presence of traffic at each intersection as well as remotely controlling the operation of the signals. The system has been validated by constructing a prototype that resembles the real application.

Traffic analysis and control using image processing

Science.gov (United States)

Senthilkumar, K.; Ellappan, Vijayan; Arun, A. R.

2017-11-01

This paper shows the work on traffic analysis and control till date. It shows an approach to regulate traffic the use of image processing and MATLAB systems. This concept uses computational images that are to be compared with original images of the street taken in order to determine the traffic level percentage and set the timing for the traffic signal accordingly which are used to reduce the traffic stoppage on traffic lights. They concept proposes to solve real life scenarios in the streets, thus enriching the traffic lights by adding image receivers like HD cameras and image processors. The input is then imported into MATLAB to be used. as a method for calculating the traffic on roads. Their results would be computed in order to adjust the traffic light timings on a particular street, and also with respect to other similar proposals but with the added value of solving a real, big instance.

Traffic management simulation development.

Science.gov (United States)

2011-01-03

Microscopic simulation can provide significant support to traffic management center (TMC) operations. However, traffic simulation applications require data that are expensive and time-consuming to collect. Data collected by TMCs can be used as a prim...

Fair and efficient prices in traffic. Propositions on price policy for the sustainable development of traffic in Switzerland

International Nuclear Information System (INIS)

Maibach, M.; Ott, W.; Schreyer, Ch.

2000-01-01

Fair and efficient prices are a central topic in traffic policy, both at the EU level and in Switzerland. They should allow the efficient use of the infrastructure, set up fair terms of competition between road and rail traffic and reduce traffic loading. At the same time, they should also make it possible to finance traffic in a sustainable manner. One of the main directions of attack is letting those responsible pay the external costs which result from traffic jams, accidents and environmental pollution. With the planned introduction of the usage-dependent heavy traffic levy, Switzerland has made an important step in the direction of true cost-allocation for goods vehicles. As for the rest of road traffic, however, considerable external costs are still not covered. On the other hand, rail traffic is not able to cover its infrastructure costs itself in spite of compensation it receives for the provision of public services

Fair and efficient prices in traffic. Propositions on price policy for the sustainable development of traffic in Switzerland

International Nuclear Information System (INIS)

Maibach, M.; Ott, W.; Schreyer, Ch.

1999-01-01

Fair and efficient prices are a central topic in traffic policy, both at the European Union level and in Switzerland. They should allow the efficient use of the infrastructure, set up fair terms of competition between road and rail traffic and reduce traffic loading. At the same time, they should also make it possible to finance traffic in a sustainable manner. One of the main directions of attack is letting those responsible pay the external costs which result from traffic jams, accidents and environmental pollution. With the planned introduction of the usage-dependent heavy traffic levy, Switzerland has made an important step in the direction of true cost-allocation for goods vehicles. As for the rest of road traffic, however, considerable external costs are still not covered. On the other hand, rail traffic is not able to cover its infrastructure costs itself in spite of compensation it receives for the provision of public services [de

A computerized traffic control algorithm to determine optimal traffic signal settings. Ph.D. Thesis - Toledo Univ.

Science.gov (United States)

Seldner, K.

1977-01-01

An algorithm was developed to optimally control the traffic signals at each intersection using a discrete time traffic model applicable to heavy or peak traffic. Off line optimization procedures were applied to compute the cycle splits required to minimize the lengths of the vehicle queues and delay at each intersection. The method was applied to an extensive traffic network in Toledo, Ohio. Results obtained with the derived optimal settings are compared with the control settings presently in use.

ON THE ARRIVAL TRAFFIC FLOW ORGANIZATION

Directory of Open Access Journals (Sweden)

Nikita A. Assorov

2017-01-01

Full Text Available This article is about air traffic flow organization, ICAO regulations describe the organizing of traffic flow as one of the purposes of air traffic control, but they don’t state exactly at what point the flow has to be organized and metered. The flight phase, where air traffic controller interferes with his instructions in order to begin organizing of all aircraft landing at a certain airport depends on the actual traffic volume per hour, airspace capacity and design.The example of air traffic situation in Moscow Domodedovo airport is described in the article, with runway 32 right in use, no significant weather, real usage of STARs, considering all the ICAO and Russian Federation regulations regarding speed control with the restrictions mentioned in AIP of Moscow Domodedovo. The purpose of the experiment is to prove the need of metering the air traffic flow on the entry points in Moscow TMA, because in case of unorganized air traffic flow approach controllers will have additional unnecessary workload.The conducted calculations show, that only 3 aircraft entering TMA on the same distance from initial approach point can be handled using only speed control and existing standard arrival procedures, in all other cases vectoring or holding areas should be used.In order to avoid such situations and increase the number of the aircraft that can be handled by the approach controller with less instructions, all the traffic arriving on the TMA entry point has to be metered by area control centre, because the air traffic control unit has much more space and time for long term speed control modifications, e.g. ±0,02 Mach. In conclusion a simple rule comes to mind – the bigger inbound traffic is, the earlier one has to organize it, in order to do it speed control, radar vectors, miles-in-trail can be used. Also new equipment and technology can help air traffic controller with this task, e.g. AMAN (arrival manager, in addition to this, the experience of

Dissociative Tendencies and Traffic Incidents

Directory of Open Access Journals (Sweden)

Valle, Virginia

2012-01-01

Full Text Available This paper analyses the relationship between dissociative experiences and road traffic incidents (crashes and traffic tickets in drivers (n=295 from Mar del Plata (Argentina city. A self-report questionnaire was applied to assess traffic crash involvement and sociodemographic variables. Dissociative tendencies were assessed by a modified version of the DES scale. To examine differences in DES scores tests of the difference of means were applied. Drivers who reported to be previously involved in traffic incidents obtained higher puntuations in the dissociative experiences scale than drivers who did not report such events. This result is observed for the total scale and for the three sub-scales (absorption, amnesia and depersonalization. However, differences appeared mainly for minor damage collisions. Further studies are needed to evaluate the role of dissociative tendencies as a risk factor in road traffic safety.

Wireless traffic steering for green cellular networks

CERN Document Server

Zhang, Shan; Zhou, Sheng; Niu, Zhisheng; Shen, Xuemin (Sherman)

2016-01-01

This book introduces wireless traffic steering as a paradigm to realize green communication in multi-tier heterogeneous cellular networks. By matching network resources and dynamic mobile traffic demand, traffic steering helps to reduce on-grid power consumption with on-demand services provided. This book reviews existing solutions from the perspectives of energy consumption reduction and renewable energy harvesting. Specifically, it explains how traffic steering can improve energy efficiency through intelligent traffic-resource matching. Several promising traffic steering approaches for dynamic network planning and renewable energy demand-supply balancing are discussed. This book presents an energy-aware traffic steering method for networks with energy harvesting, which optimizes the traffic allocated to each cell based on the renewable energy status. Renewable energy demand-supply balancing is a key factor in energy dynamics, aimed at enhancing renewable energy sustainability to reduce on-grid energy consum...

Controlled Traffic Farming

OpenAIRE

Controlled Traffic Farming Europe

2011-01-01

Metadata only record Controlled Traffic Farming (CTF) is a farming method used to reduce soil compaction, decrease inputs, and improve soil structure when coupled with reduced-till or no-till practices. This practices utilizes permanent traffic/wheel zones to limit soil compaction to a specific area. This website provides practical information on CTF, case studies, workshops, and links to additional resources.

Traffic flow wide-area surveillance system definition

Energy Technology Data Exchange (ETDEWEB)

Allgood, G.O.; Ferrell, R.K.; Kercel, S.W.; Abston, R.A.; Carnal, C.L. [Oak Ridge National Lab., TN (United States); Moynihan, P.I. [Jet Propulsion Lab., Pasadena, CA (United States)

1994-11-01

Traffic Flow Wide-Area Surveillance (TFWAS) is a system for assessing the state of traffic flow over a wide area for enhanced traffic control and improved traffic management and planning. The primary purpose of a TFWAS system is to provide a detailed traffic flow description and context description to sophisticated traffic management and control systems being developed or envisioned for the future. A successful TFWAS system must possess the attributes of safety, reconfigurability, reliability, and expandability. The primary safety premise of TFWAS is to ensure that no action or failure of the TFWAS system or its components can result in risk of injury to humans. A wide variety of communication techniques is available for use with TFWAS systems. These communication techniques can be broken down into two categories, landlines and wireless. Currently used and possible future traffic sensing technologies have been examined. Important criteria for selecting TFWAS sensors include sensor capabilities, costs, operational constraints, sensor compatibility with the infrastructure, and extent. TFWAS is a concept that can take advantage of the strengths of different traffic sensing technologies, can readily adapt to newly developed technologies, and can grow with the development of new traffic control strategies. By developing innovative algorithms that will take information from a variety of sensor types and develop descriptions of traffic flows over a wide area, a more comprehensive understanding of the traffic state can be provided to the control system to perform the most reasonable control actions over the entire wide area. The capability of characterizing the state of traffic over an entire region should revolutionize developments in traffic control strategies.

Qualitative and Quantitative Analysis of Congested Marine Traffic Environment – An Application Using Marine Traffic Simulation System

Directory of Open Access Journals (Sweden)

Kazuhiko Hasegawa

2013-06-01

Full Text Available Difficulty of sailing is quite subjective matter. It depends on various factors. Using Marine Traffic Simulation System (MTSS developed by Osaka University this challenging subject is discussed. In this system realistic traffic flow including collision avoidance manoeuvres can be reproduced in a given area. Simulation is done for southward of Tokyo Bay, Strait of Singapore and off-Shanghai area changing traffic volume from 5 or 50 to 150 or 200% of the present volume. As a result, strong proportional relation between near-miss ratio and traffic density per hour per sailed area is found, independent on traffic volume, area size and configuration. The quantitative evaluation index of the difficulty of sailing, here called risk rate of the area is defined using thus defined traffic density and near-miss ratio.

32 CFR 634.28 - Traffic accident investigation.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Traffic accident investigation. 634.28 Section... ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.28 Traffic accident investigation. Installation law enforcement personnel must make detailed investigations of...

Flow level performance approximations for elastic traffic integrated with prioritized stream traffic

NARCIS (Netherlands)

Malhotra, R.; Berg, J.L. van den

2007-01-01

Almost all traffic in todays networks can be classified as being either stream or elastic. The support of these two traffic types is possible either with a Differentiated (DiffServ) or an Integrated Services (IntServ) architecture. However, both DiffServ and IntServ rely on efficient scheduling

Criterion for traffic phases in single vehicle data and empirical test of a microscopic three-phase traffic theory

International Nuclear Information System (INIS)

Kerner, Boris S; Klenov, Sergey L; Hiller, Andreas

2006-01-01

Based on empirical and numerical microscopic analyses, the physical nature of a qualitatively different behaviour of the wide moving jam phase in comparison with the synchronized flow phase-microscopic traffic flow interruption within the wide moving jam phase-is found. A microscopic criterion for distinguishing the synchronized flow and wide moving jam phases in single vehicle data measured at a single freeway location is presented. Based on this criterion, empirical microscopic classification of different local congested traffic states is performed. Simulations made show that the microscopic criterion and macroscopic spatiotemporal objective criteria lead to the same identification of the synchronized flow and wide moving jam phases in congested traffic. Microscopic models in the context of three-phase traffic theory have been tested based on the microscopic criterion for the phases in congested traffic. It is found that microscopic three-phase traffic models can explain both microscopic and macroscopic empirical congested pattern features. It is obtained that microscopic frequency distributions for vehicle speed difference as well as fundamental diagrams and speed correlation functions can depend on the spatial co-ordinate considerably. It turns out that microscopic optimal velocity (OV) functions and time headway distributions are not necessarily qualitatively different, even if local congested traffic states are qualitatively different. The reason for this is that important spatiotemporal features of congested traffic patterns are lost in these as well as in many other macroscopic and microscopic traffic characteristics, which are widely used as the empirical basis for a test of traffic flow models, specifically, cellular automata traffic flow models

Regulatory measures for traffic safety

International Nuclear Information System (INIS)

Veerapur, R.D.; Bharambe, S.D.; Patnaik, S.K.; Tandle, A.K.; Sonawane, K.A.; Kumar, Rajesh; Venkat Subramanian, K.

2017-01-01

Traffic safety is an issue related to occupational safety not restricted alone to the transportation but extends beyond. BARC has many facilities spread across large area in Mumbai and outside Mumbai. BARC deploys large number of buses, mini buses, jeeps and cars for commuting its employees to reach BARC and for commuting within BARC premises. Additionally, trucks, fire tenders, trailers etc. are also deployed for transportation of materials. No moving vehicle is ever free of the possibility of involvement in an accident. Vehicular accidents and the fatalities on road are the result of inter-play of a number of factors. The vehicle population has been steadily increasing with the pace picking up significantly in recent past. Increase in vehicle population in the face of limited road space used by a large variety of traffic has heightened the need and urgency for a well-thought-out road safety. Therefore, existence of regulatory authority to regulate traffic and vehicles to ensure safety of its employees and vehicles is very essential. BARC Traffic Safety Committee (BTSC), which is the regulating body for traffic safety is responsible for ensuring overall traffic safety. (author)

Traffic calming for the prevention of road traffic injuries: systematic review and meta-analysis.

Science.gov (United States)

Bunn, F; Collier, T; Frost, C; Ker, K; Roberts, I; Wentz, R

2003-09-01

To assess whether area-wide traffic calming schemes can reduce road crash related deaths and injuries. Systematic review and meta-analysis. Cochrane Injuries Group Specialised Register, Cochrane Central Register of Controlled Trials, Medline, EMBASE, Sociological Abstracts Science (and social science) citation index, National Technical Information service, Psychlit, Transport Research Information Service, International Road Research Documentation, and Transdoc, and web sites of road safety organisation were searched; experts were contacted, conference proceedings were handsearched, and relevant reference lists were checked. Randomised controlled trials, and controlled before/after studies of area-wide traffic calming schemes designed to discourage and slow down through traffic on residential roads. Data were collected on road user deaths, injuries, and traffic crashes. For each study rate ratios were calculated, the ratio of event rates before and after intervention in the traffic calmed area divided by the corresponding ratio of event rates in the control area, which were pooled to give an overall estimate using a random effects model. Sixteen controlled before/after studies met our inclusion criteria. Eight studies reported the number of road user deaths: pooled rate ratio 0.63 (95% confidence interval (CI) 0.14 to 2.59). Sixteen studies reported the number of injuries (fatal and non-fatal): pooled rate ratio 0.89 (95% CI 0.80 to 1.00). All studies were in high income countries. Area-wide traffic calming in towns and cities has the potential to reduce road traffic injuries. However, further rigorous evaluations of this intervention are needed, especially in low and middle income countries.

Model for traffic emissions estimation

Science.gov (United States)

Alexopoulos, A.; Assimacopoulos, D.; Mitsoulis, E.

A model is developed for the spatial and temporal evaluation of traffic emissions in metropolitan areas based on sparse measurements. All traffic data available are fully employed and the pollutant emissions are determined with the highest precision possible. The main roads are regarded as line sources of constant traffic parameters in the time interval considered. The method is flexible and allows for the estimation of distributed small traffic sources (non-line/area sources). The emissions from the latter are assumed to be proportional to the local population density as well as to the traffic density leading to local main arteries. The contribution of moving vehicles to air pollution in the Greater Athens Area for the period 1986-1988 is analyzed using the proposed model. Emissions and other related parameters are evaluated. Emissions from area sources were found to have a noticeable share of the overall air pollution.

OPTIMASI BANDWITH MENGGUNAKAN TRAFFIC SHAPPING

Directory of Open Access Journals (Sweden)

Imam Riadi

2010-01-01

Full Text Available Perkembangan layanan komunikasi telah berkembang sangat pesat. Salah satunya adalah pemanfaatan penggunaan bandwith untuk mengakases jaringan Internet. Traffic shapping bandwidth dapat memberikan efesiensi dalam hal pemanfaatan bandwidth pada instansi yang melakukan manajemen dalam lalulintas jaringannya. Metode yang digunakan dalam penelitian ini adalah metode literatur yaitu metode pengumpulan data yang dilakukan dengan mengumpulkan sumber- sumber data yang terkait dan metode eksperimen yaitu melakukan penelitian dengan mengkonfigurasi Mikrotik RouterOS untuk melakukan traffic shapping bandwidth. Hasil penelitian ini adalah router yang dapat melakukan traffic shapping sehingga kualitas koneksi menjadi lebih baik untuk mengakses dan mengambil data dari sebuah website. Kata kunci : Optimasi, Bandwith, Traffic Shapping, MikroTik. 

Bicycle traffic in urban areas

Directory of Open Access Journals (Sweden)

Anđelković Zorica

2015-01-01

Full Text Available Cycling is a term describing the use of bicycles, but also any mean of transport driven solely by human power. Development of bicycle traffic in urban areas involves construction of cycling infrastructure, adapting streets and other traffic infrastructure to a form suitable for cycling and other means of transport (individual motorized traffic, public transport, walking, ensuring the adequate budget and systematic planning and development of sustainable transport in cities. The paper presents basic settings and conditions as input elements to plan bicycle traffic in urban areas, as well as program- design conditions which lead the activities of planners and designers of urban roads in connection with cyclists.

Traffic light control by multiagent reinforcement learning systems

NARCIS (Netherlands)

Bakker, B.; Whiteson, S.; Kester, L.; Groen, F.C.A.; Babuška, R.; Groen, F.C.A.

2010-01-01

Traffic light control is one of the main means of controlling road traffic. Improving traffic control is important because it can lead to higher traffic throughput and reduced traffic congestion. This chapter describes multiagent reinforcement learning techniques for automatic optimization of

Traffic Light Control by Multiagent Reinforcement Learning Systems

NARCIS (Netherlands)

Bakker, B.; Whiteson, S.; Kester, L.J.H.M.; Groen, F.C.A.

2010-01-01

Traffic light control is one of the main means of controlling road traffic. Improving traffic control is important because it can lead to higher traffic throughput and reduced traffic congestion. This chapter describes multiagent reinforcement learning techniques for automatic optimization of

Capacity planning of link restorable optical networks under dynamic change of traffic

Science.gov (United States)

Ho, Kwok Shing; Cheung, Kwok Wai

2005-11-01

Future backbone networks shall require full-survivability and support dynamic changes of traffic demands. The Generalized Survivable Networks (GSN) was proposed to meet these challenges. GSN is fully-survivable under dynamic traffic demand changes, so it offers a practical and guaranteed characterization framework for ASTN / ASON survivable network planning and bandwidth-on-demand resource allocation 4. The basic idea of GSN is to incorporate the non-blocking network concept into the survivable network models. In GSN, each network node must specify its I/O capacity bound which is taken as constraints for any allowable traffic demand matrix. In this paper, we consider the following generic GSN network design problem: Given the I/O bounds of each network node, find a routing scheme (and the corresponding rerouting scheme under failure) and the link capacity assignment (both working and spare) which minimize the cost, such that any traffic matrix consistent with the given I/O bounds can be feasibly routed and it is single-fault tolerant under the link restoration scheme. We first show how the initial, infeasible formal mixed integer programming formulation can be transformed into a more feasible problem using the duality transformation of the linear program. Then we show how the problem can be simplified using the Lagrangian Relaxation approach. Previous work has outlined a two-phase approach for solving this problem where the first phase optimizes the working capacity assignment and the second phase optimizes the spare capacity assignment. In this paper, we present a jointly optimized framework for dimensioning the survivable optical network with the GSN model. Experiment results show that the jointly optimized GSN can bring about on average of 3.8% cost savings when compared with the separate, two-phase approach. Finally, we perform a cost comparison and show that GSN can be deployed with a reasonable cost.

Self-Organization in 2D Traffic Flow Model with Jam-Avoiding Drive

Science.gov (United States)

Nagatani, Takashi

1995-04-01

A stochastic cellular automaton (CA) model is presented to investigate the traffic jam by self-organization in the two-dimensional (2D) traffic flow. The CA model is the extended version of the 2D asymmetric exclusion model to take into account jam-avoiding drive. Each site contains either a car moving to the up, a car moving to the right, or is empty. A up car can shift right with probability p ja if it is blocked ahead by other cars. It is shown that the three phases (the low-density phase, the intermediate-density phase and the high-density phase) appear in the traffic flow. The intermediate-density phase is characterized by the right moving of up cars. The jamming transition to the high-density jamming phase occurs with higher density of cars than that without jam-avoiding drive. The jamming transition point p 2c increases with the shifting probability p ja. In the deterministic limit of p ja=1, it is found that a new jamming transition occurs from the low-density synchronized-shifting phase to the high-density moving phase with increasing density of cars. In the synchronized-shifting phase, all up cars do not move to the up but shift to the right by synchronizing with the move of right cars. We show that the jam-avoiding drive has an important effect on the dynamical jamming transition.

The importance of spatial orientation and knowledge of traffic signs for children's traffic safety.

Science.gov (United States)

Trifunović, Aleksandar; Pešić, Dalibor; Čičević, Svetlana; Antić, Boris

2017-05-01

Pre-school children, as well as children from lower grades in primary school, who although rarely, completely independently participate in traffic, represent a vulnerable population from the standpoint of traffic safety. The greatest number of children were injured or killed in road traffic crashes on their way from home to kindergarten or school. Mostly due to lack of experience, children's behavior is confusing and often reckless and hasty. Safe behavior in the traffic environment demands certain cognitive skills. Unlike adults, children have less than fully developed peripheral vision. Also, changes occur in color perception, i.e. discrimination. All this leads to the conclusion that the stage of physical and mental development of the child is very important for safe participation in traffic. So, to estimate if they are sufficiently equipped to participate safely in traffic, a sensitive test for young children that may be suitable for their level of cognitive development is required. Accordingly, road safety education should be arranged in such a way that considers the child's level of development, as has been shown to be more effective when started at younger ages. Play is the most natural and easiest way of learning because it is the lens through which children experience their world, and the world of others. Having this in mind, if we want to measure the abilities of a child, and their preparedness for safety participation in traffic, unavoidable is to use non-verbal tests. The purpose of this study is to explore primary schooler's spatial, and abilities of color perception and memorization, as well as their performances in interpreting the meaning of traffic signs. In addition, neighborhood environmental correlates (rural-urban) and possible individual differences influences on the relationship among these abilities was examined. Knowledge about these factors affecting children's safety can be applied to improve relevant intervention measures for promoting

Traffic Information Unit, Traffic Information System, Vehicle Management System, Vehicle, and Method of Controlling a Vehicle

NARCIS (Netherlands)

Papp, Z.; Doodeman, G.J.N.; Nelisse, M.W.; Sijs, J.; Theeuwes, J.A.C.; Driessen, B.J.F.

2010-01-01

A traffic information unit (MD1, MD2, MD3) according to the invention comprises a facility (MI) for tracking vehicle state information of individual vehicles present at a traffic infrastructure and a facility (T) for transmitting said vehicle state information to a vehicle (70B, 70E). A traffic

Navigators’ Behavior in Traffic Separation Schemes

Directory of Open Access Journals (Sweden)

Zbigniew Pietrzykowski

2015-03-01

Full Text Available One of the areas of decision support in the navigational ship conduct process is a Traffic Separation Scheme. TSSs are established in areas with high traffic density, often near the shore and in port approaches. The main purpose of these schemes is to improve maritime safety by channeling vessel traffic into streams. Traffic regulations as well as ships behavior in real conditions in chosen TSSs have been analyzed in order to develop decision support algorithms.

VBR video traffic models

CERN Document Server

Tanwir, Savera

2014-01-01

There has been a phenomenal growth in video applications over the past few years. An accurate traffic model of Variable Bit Rate (VBR) video is necessary for performance evaluation of a network design and for generating synthetic traffic that can be used for benchmarking a network. A large number of models for VBR video traffic have been proposed in the literature for different types of video in the past 20 years. Here, the authors have classified and surveyed these models and have also evaluated the models for H.264 AVC and MVC encoded video and discussed their findings.

Photonics approach to traffic signs

Science.gov (United States)

Litwin, Dariusz; Galas, Jacek; CzyŻewski, Adam; Rymsza, Barbara; Kornalewski, Leszek; Kryszczyński, Tadeusz; Mikucki, Jerzy; Wikliński, Piotr; Daszkiewicz, Marek; Malasek, Jacek

2016-12-01

The automotive industry has been always a driving force for all economies. Despite of its beneficial meaning to every society it brings also many issues including wide area of road safety. The latter has been enforced by the increasing number of cars and the dynamic development of the traffic as a whole. Road signs and traffic lights are crucial in context of good traffic arrangement and its fluency. Traffic designers are used to treat horizontal road signs independently of vertical signs. However, modern light sources and growing flexibility in shaping optical systems create opportunity to design more advanced and smart solutions. In this paper we present an innovative, multidisciplinary approach that consists in tight interdependence of different traffic signals. We describe new optical systems together with their influence on the perception of the road user. The analysis includes maintenance and visibility in different weather conditions. A special attention has been focused on intersections of complex geometry.

Traffic accidents: an econometric investigation

OpenAIRE

Tito Moreira; Adolfo Sachsida; Loureiro Paulo

2004-01-01

Based on a sample of drivers in Brasilia's streets, this article investigates whether distraction explains traffic accidents. A probit model is estimated to determine the predictive power of several variables on traffic accidents. The main conclusion drawn from this study is that the proxies used to measure distraction, such as the use of cell phones and cigarette smoking in a moving vehicle, are significant factors in determining traffic accidents.

Call Arrival Rate Prediction and Blocking Probability Estimation for Infrastructure based Mobile Cognitive Radio Personal Area Network

Directory of Open Access Journals (Sweden)

Neeta Nathani

2017-08-01

Full Text Available The Cognitive Radio usage has been estimated as non-emergency service with low volume traffic. Present work proposes an infrastructure based Cognitive Radio network and probability of success of CR traffic in licensed band. The Cognitive Radio nodes will form cluster. The cluster nodes will communicate on Industrial, Scientific and Medical band using IPv6 over Low-Power Wireless Personal Area Network based protocol from sensor to Gateway Cluster Head. For Cognitive Radio-Media Access Control protocol for Gateway to Cognitive Radio-Base Station communication, it will use vacant channels of licensed band. Standalone secondary users of Cognitive Radio Network shall be considered as a Gateway with one user. The Gateway will handle multi-channel multi radio for communication with Base Station. Cognitive Radio Network operators shall define various traffic data accumulation counters at Base Station for storing signal strength, Carrier-to-Interference and Noise Ratio, etc. parameters and record channel occupied/vacant status. The researches has been done so far using hour as interval is too long for parameters like holding time expressed in minutes and hence channel vacant/occupied status time is only probabilistically calculated. In the present work, an infrastructure based architecture has been proposed which polls channel status each minute in contrary to hourly polling of data. The Gateways of the Cognitive Radio Network shall monitor status of each Primary User periodically inside its working range and shall inform to Cognitive Radio- Base Station for preparation of minutewise database. For simulation, the occupancy data for all primary user channels were pulled in one minute interval from a live mobile network. Hourly traffic data and minutewise holding times has been analyzed to optimize the parameters of Seasonal Auto Regressive Integrated Moving Average prediction model. The blocking probability of an incoming Cognitive Radio call has been

ReFlow: Reports on Internet Traffic

NARCIS (Netherlands)

Hoogesteger, Martijn; de Oliveira Schmidt, R.; Sperotto, Anna; Pras, Aiko

Internet traffic statistics can provide valuable information to network analysts and researchers about the traffic, technologies and main characteristics of today’s networks. For many years Internet2 maintained a public website with statistics about the traffic in the Abilene network. This site was

32 CFR 634.25 - Installation traffic codes.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Installation traffic codes. 634.25 Section 634.25 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.25 Installation traffic codes. (a) Installation or activit...

Road traffic noise: self-reported noise annoyance versus GIS modelled road traffic noise exposure.

Science.gov (United States)

Birk, Matthias; Ivina, Olga; von Klot, Stephanie; Babisch, Wolfgang; Heinrich, Joachim

2011-11-01

self-reported road traffic noise annoyance is commonly used in epidemiological studies for assessment of potential health effects. Alternatively, some studies have used geographic information system (GIS) modelled exposure to road traffic noise as an objective parameter. The aim of this study was to analyse the association between noise exposure due to neighbouring road traffic and the noise annoyance of adults, taking other determinants into consideration. parents of 951 Munich children from the two German birth cohorts GINIplus and LISAplus reported their annoyance due to road traffic noise at home. GIS modelled road traffic noise exposure (L(den), maximum within a 50 m buffer) from the noise map of the city of Munich was available for all families. GIS-based calculated distance to the closest major road (≥10,000 vehicles per day) and questionnaire based-information about family income, parental education and the type of the street of residence were explored for their potential influence. An ordered logit regression model was applied. The noise levels (L(den)) and the reported noise annoyance were compared with an established exposure-response function. the correlation between noise annoyance and noise exposure (L(den)) was fair (Spearman correlation r(s) = 0.37). The distance to a major road and the type of street were strong predictors for the noise annoyance. The annoyance modelled by the established exposure-response function and that estimated by the ordered logit model were moderately associated (Pearson's correlation r(p) = 0.50). road traffic noise annoyance was associated with GIS modelled neighbouring road traffic noise exposure (L(den)). The distance to a major road and the type of street were additional explanatory factors of the noise annoyance appraisal.

Bcl-xL regulates CD1d-mediated antigen presentation to NKT cells by altering CD1d trafficking through the endocytic pathway.

Science.gov (United States)

Subrahmanyam, Priyanka B; Carey, Gregory B; Webb, Tonya J

2014-09-01

NKT cells are a unique subset of T cells that recognize glycolipid Ags presented in the context of CD1d molecules. NKT cells mount strong antitumor responses and are a major focus in developing effective cancer immunotherapy. It is known that CD1d molecules are constantly internalized from the cell surface, recycled through the endocytic compartments, and re-expressed on the cell surface. However, little is known about the regulation of CD1d-mediated Ag processing and presentation in B cell lymphoma. Prosurvival factors of the Bcl-2 family, such as Bcl-xL, are often upregulated in B cell lymphomas and are intimately linked to sphingolipid metabolism, as well as the endocytic compartments. We hypothesized that Bcl-xL can regulate CD1d-mediated Ag presentation to NKT cells. We found that overexpression or induction of Bcl-xL led to increased Ag presentation to NKT cells. Conversely, the inhibition or knockdown of Bcl-xL led to decreased NKT cell activation. Furthermore, knockdown of Bcl-xL resulted in the loss of CD1d trafficking to lysosome-associated membrane protein 1(+) compartments. Rab7, a late endosomal protein, was upregulated and CD1d molecules accumulated in the Rab7(+) late endosomal compartment. These results demonstrate that Bcl-xL regulates CD1d-mediated Ag processing and presentation to NKT cells by altering the late endosomal compartment and changing the intracellular localization of CD1d. Copyright © 2014 by The American Association of Immunologists, Inc.

Predicting Information Flows in Network Traffic.

Science.gov (United States)

Hinich, Melvin J.; Molyneux, Robert E.

2003-01-01

Discusses information flow in networks and predicting network traffic and describes a study that uses time series analysis on a day's worth of Internet log data. Examines nonlinearity and traffic invariants, and suggests that prediction of network traffic may not be possible with current techniques. (Author/LRW)

Spectral Analysis of Traffic Functions in Urban Areas

Directory of Open Access Journals (Sweden)

Florin Nemtanu

2015-12-01

Full Text Available The paper is focused on the Fourier transform application in urban traffic analysis and the use of said transform in traffic decomposition. The traffic function is defined as traffic flow generated by different categories of traffic participants. A Fourier analysis was elaborated in terms of identifying the main traffic function components, called traffic sub-functions. This paper presents the results of the method being applied in a real case situation, that is, an intersection in the city of Bucharest where the effect of a bus line was analysed. The analysis was done using different time scales, while three different traffic functions were defined to demonstrate the theoretical effect of the proposed method of analysis. An extension of the method is proposed to be applied in urban areas, especially in the areas covered by predictive traffic control.

Competitive Traffic Assignment in Road Networks

Directory of Open Access Journals (Sweden)

Krylatov Alexander Y.

2016-09-01

Full Text Available Recently in-vehicle route guidance and information systems are rapidly developing. Such systems are expected to reduce congestion in an urban traffic area. This social benefit is believed to be reached by imposing the route choices on the network users that lead to the system optimum traffic assignment. However, guidance service could be offered by different competitive business companies. Then route choices of different mutually independent groups of users may reject traffic assignment from the system optimum state. In this paper, a game theoretic approach is shown to be very efficient to formalize competitive traffic assignment problem with various groups of users in the form of non-cooperative network game with the Nash equilibrium search. The relationships between the Wardrop’s system optimum associated with the traffic assignment problem and the Nash equilibrium associated with the competitive traffic assignment problem are investigated. Moreover, some related aspects of the Nash equilibrium and the Wardrop’s user equilibrium assignments are also discussed.

Is vehicle automation enough to prevent crashes? Role of traffic operations in automated driving environments for traffic safety.

Science.gov (United States)

Jeong, Eunbi; Oh, Cheol; Lee, Seolyoung

2017-07-01

Automated driving systems (ADSs) are expected to prevent traffic accidents caused by driver carelessness on freeways. There is no doubt regarding this safety benefit if all vehicles in the transportation system were equipped with ADSs; however, it is implausible to expect that ADSs will reach 100% market penetration rate (MPR) in the near future. Therefore, the following question arises: 'Can ADSs, which consider only situations in the vicinity of an equipped vehicle, really contribute to a significant reduction in traffic accidents?' To address this issue, the interactions between equipped and unequipped vehicles must be investigated, which is the purpose of this study. This study evaluated traffic safety at different MPRs based on a proposed index to represent the overall rear-end crash risk of the traffic stream. Two approaches were evaluated for adjusting longitudinal vehicle maneuvers: vehicle safety-based maneuvering (VSM), which considers the crash risk of an equipped vehicle and its neighboring vehicles, and traffic safety-based maneuvering (TSM), which considers the overall crash risk in the traffic stream. TSM assumes that traffic operational agencies are able to monitor all the vehicles and to intervene in vehicle maneuvering. An optimization process, which attempts to obtain vehicle maneuvering control parameters to minimize the overall crash risk, is integrated into the proposed evaluation framework. The main purpose of employing the optimization process for vehicle maneuvering in this study is to identify opportunities to improve traffic safety through effective traffic management rather than developing a vehicle control algorithm that can be implemented in practice. The microscopic traffic simulator VISSIM was used to simulate the freeway traffic stream and to conduct systematic evaluations based on the proposed methodology. Both TSM and VSM achieved significant reductions in the potential for rear-end crashes. However, TSM obtained much greater

Analysis of Malicious Traffic in Modbus/TCP Communications

Science.gov (United States)

Kobayashi, Tiago H.; Batista, Aguinaldo B.; Medeiros, João Paulo S.; Filho, José Macedo F.; Brito, Agostinho M.; Pires, Paulo S. Motta

This paper presents the results of our analysis about the influence of Information Technology (IT) malicious traffic on an IP-based automation environment. We utilized a traffic generator, called MACE (Malicious trAffic Composition Environment), to inject malicious traffic in a Modbus/TCP communication system and a sniffer to capture and analyze network traffic. The realized tests show that malicious traffic represents a serious risk to critical information infrastructures. We show that this kind of traffic can increase latency of Modbus/TCP communication and that, in some cases, can put Modbus/TCP devices out of communication.

30 CFR 56.9100 - Traffic control.

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Traffic control. 56.9100 Section 56.9100 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Dumping Traffic Safety § 56.9100 Traffic control. To provide for the safe movement of self-propelled...

Life Times of Simulated Traffic Jams

Science.gov (United States)

Nagel, Kai

We study a model for freeway traffic which includes strong noise taking into account the fluctuations of individual driving behavior. The model shows emergent traffic jams with a self-similar appearance near the throughput maximum of the traffic. The lifetime distribution of these jams shows a short scaling regime, which gets considerably longer if one reduces the fluctuations when driving at maximum speed but leaves the fluctuations for slowing down or accelerating unchanged. The outflow from a traffic jam self-organizes into this state of maximum throughput.

2016 Traffic Safety Culture Index

Science.gov (United States)

... Newsroom SEARCH Driver Behavior & Performance 2016 Traffic Safety Culture Index This report presents the results of our annual Traffic Safety Culture Index survey, providing data on the attitudes and ...

Procedure for Marine Traffic Simulation with AIS Data

Directory of Open Access Journals (Sweden)

Rina Miyake

2015-03-01

Full Text Available It is essential to evaluate safety of marine traffic for the improvement of efficiency and safety of marine traffic. Spread of AIS makes observation of actual marine traffic more easily and faster than before. Besides, description of collision avoidance behaviours of ships are indispensable to simulate a realistic marine traffic. It is important to develop and implement an algorithm of collision avoidance corresponding to a target traffic or target area into the marine traffic simulation because actual actions for collision avoidance depend on circumstances where ships are sailing. The authors developed an automated marine traffic simulation system with AIS data. And in this paper, we proposed a series of systematic procedures for marine traffic simulation including analysing for collision avoidance behaviours using AIS data.

Impact Analysis of Land Use on Traffic Congestion Using Real-Time Traffic and POI

OpenAIRE

Zhang, Tianqi; Sun, Lishan; Yao, Liya; Rong, Jian

2017-01-01

This paper proposed a new method to describe, compare, and classify the traffic congestion points in Beijing, China, by using the online map data and further revealed the relationship between traffic congestion and land use. The data of the point of interest (POI) and the real-time traffic was extracted from an electronic map of the area in the fourth ring road of Beijing. The POIs were quantified based on the architectural area of the land use; the congestion points were identified based on ...

Systemic Approach to Traffic Evaluation of Mostar Airport

Directory of Open Access Journals (Sweden)

Eldo Raguž

2005-11-01

Full Text Available The attempt of this work is to systematically find solutionsfor Mostar Airport development through technical and technologicalharmonization of traffic processes undertaken in twoseparate organizations - airport and air traffic control and coordinationbetween other traffic branches. The work uses theindicators of traffic flows and tourist trends in the region, andtogether with the mentioned simulations it attempts to evaluatethe traffic potentials in the region by affecting the change in thecurrent negative traffic flows at Mostar Airport.

Traffic noise in Hyderabad city, part-II. vehicular contribution to road traffic noise

International Nuclear Information System (INIS)

Sheikh, G.H.

2001-01-01

The results of a road traffic noise survey carried out in Hyderabad city showed that the levels of traffic noise in the City are alarmingly high and much beyond the comfortable limits. There, in order to investigate the level of the noise emitted by different types of vehicles plying on the city roads and to assess their individual contribution to high level traffic noise, studies have been carried out on the measurement of noise emitted by motorcycles, buses, auto-rickshaws, and motor vehicle horns as they normally move on the city roads. The data collected has been analyzed for L/sub v99/, L/sub v90/, L/sub v50/, L/sub v10/ and L/sub v1/ and results are discussed with reference to the existing motor vehicle rules in Pakistan and motor vehicle noise emission limits set by the EEC and other developed countries. Some suggestion have also been made to limit high level traffic noise. (author)

Light signals for road traffic control.

NARCIS (Netherlands)

Schreuder, D.A.

1981-01-01

Signals for road traffic control are a major constituent of the modern traffic scene, particularly in built-up areas. A vast amount of research has been executed in the last two decennia, resulting in a fairly generally accepted view on what the requirements for effective traffic lights are. For the

Road Traffic in China

NARCIS (Netherlands)

Jie, L.; Van Zuylen, H.J.

2014-01-01

Traffic is tightly related to the social and economic development in a country. In China the development of the economy has been very fast in the past 30 years and this is still continuing. The transport infrastructure shows a similar pattern, while traffic is also rapidly growing. In urban areas

On traffic modelling in GPRS networks

DEFF Research Database (Denmark)

Madsen, Tatiana Kozlova; Schwefel, Hans-Peter; Prasad, Ramjee

2005-01-01

Optimal design and dimensioning of wireless data networks, such as GPRS, requires the knowledge of traffic characteristics of different data services. This paper presents an in-detail analysis of an IP-level traffic measurements taken in an operational GPRS network. The data measurements reported...... here are done at the Gi interface. The aim of this paper is to reveal some key statistics of GPRS data applications and to validate if the existing traffic models can adequately describe traffic volume and inter-arrival time distribution for different services. Additionally, we present a method of user...

Enhancing the Quality of Service for Real Time Traffic over Optical Burst Switching (OBS Networks with Ensuring the Fairness for Other Traffics.

Directory of Open Access Journals (Sweden)

Mohammed A Al-Shargabi

Full Text Available Optical burst switching (OBS networks have been attracting much consideration as a promising approach to build the next generation optical Internet. A solution for enhancing the Quality of Service (QoS for high priority real time traffic over OBS with the fairness among the traffic types is absent in current OBS' QoS schemes. In this paper we present a novel Real Time Quality of Service with Fairness Ratio (RT-QoSFR scheme that can adapt the burst assembly parameters according to the traffic QoS needs in order to enhance the real time traffic QoS requirements and to ensure the fairness for other traffic. The results show that RT-QoSFR scheme is able to fulfill the real time traffic requirements (end to end delay, and loss rate ensuring the fairness for other traffics under various conditions such as the type of real time traffic and traffic load. RT-QoSFR can guarantee that the delay of the real time traffic packets does not exceed the maximum packets transfer delay value. Furthermore, it can reduce the real time traffic packets loss, at the same time guarantee the fairness for non real time traffic packets by determining the ratio of real time traffic inside the burst to be 50-60%, 30-40%, and 10-20% for high, normal, and low traffic loads respectively.

Structuring of Road Traffic Flows

Directory of Open Access Journals (Sweden)

Planko Rožić

2005-09-01

Full Text Available Systemic traffic count on the Croatian road network hasbeen carried out for more than three decades in different ways.During this period a large number of automatic traffic countershave been installed, and they operate on different principles.The traffic count has been analyzed from the aspect of vehicleclassification. The count results can be only partly comparedsince they yield different structures of traffic flows. Special analysisrefers to the classification of vehicles by automatic trafficcounters.During the research, a database has been formed with physicalelements of vehicles of over five thousand vehicle types. Theresearch results prove that the vehicle length only is not sufficientfor the classification of vehicles, the way it is used in thepresent automatic traffic counts, but rather the number of axles,the wheelbase as well as the front and rear overhangs needto be considered as well. Therefore, the detector system shouldapply also the detector of axles.The results have been presented that were obtained as partof the program TEST- Technological, research, developmentproject supported by the Minist1y of Science, Education andSport.

Visual Analysis in Traffic & Re-identification

DEFF Research Database (Denmark)

Møgelmose, Andreas

and analysis, and person re-identification. In traffic sign detection, the work comprises a thorough survey of the state of the art, assembly of the worlds largest public dataset with U.S. traffic signs, and work in machine learning based detection algorithms. It was shown that detection of U.S. traffic signs...

Some random models in traffic science

Energy Technology Data Exchange (ETDEWEB)

Hjorth, U.

1996-06-01

We give an overview of stochastic models for the following traffic phenomena. Models for traffic flow including gaps and capacities for lanes, crossings and roundabouts. Models for wanted and achieved speed distributions. Mode selection models including dispersed equilibrium models and traffic accident models. Also some statistical questions are discussed. 60 refs, 1 tab

Autosolitons in applied physics and traffic flow

International Nuclear Information System (INIS)

Kerner, B.S.

1996-01-01

A review of investigations of autosolitons in nonlinear systems which are of interest for the applied physics and for the transportation research is presented. Autosolitons are solitary intrinsic states which can be formed in a broad class of physical, chemical, biological dissipative distributed media and in traffic flow. Properties of autosolitons which are general for physical systems and for traffic flow will be discussed. Based on results of recent investigations of traffic jams in traffic flow, a comparison of nonlinear characteristics of traffic jams and with nonlinear properties of autosolitons which can be formed in active systems with diffusion will be given. Forms, properties, processes of evolution of autosolitons in traffic flow, in semiconductors and in gas discharge plasma are considered. copyright 1996 American Institute of Physics

Distraction-related road traffic collisions

African Journals Online (AJOL)

drivers involved in road traffic collisions (RTC) were using mobile phones. Our study supports ... while driving. Keywords: Distraction, prevention, road traffic collision, mobile phone. ..... keeps us connected with others with great advantages.

Adaptability of the Logistics System in National Economic Mobilization Based on Blocking Flow Theory

Directory of Open Access Journals (Sweden)

Xiangyuan Jing

2014-01-01

Full Text Available In the process of national economic mobilization, the logistics system usually suffers from negative impact and/or threats of such emergency events as wars and accidents, which implies that adaptability of the logistics system directly determines realization of economic mobilization. And where the real-time rescue operation is concerned, heavy traffic congestion is likely to cause a great loss of or damage to human beings and their properties. To deal with this situation, this article constructs a blocking-resistance optimum model and an optimum restructuring model based on blocking flow theories, of which both are illustrated by numerical cases and compared in characteristics and application. The design of these two models is expected to eliminate or alleviate the congestion situation occurring in the logistics system, thus effectively enhancing its adaptability in the national economic mobilization process.

Traffic noise in Hyderabad city. part I: road traffic noise

International Nuclear Information System (INIS)

Shaikh, G.H.; Shaikh, Q.

2000-01-01

Traffic noise survey was conducted at 20 sites in different areas and localities in Hyderabad city and each site noise data was collected continuously from 0800 to 2000 h. The data was analyzed for L/sub A99/, L/sub A90/, L/sub A50/, L/sub 10/ and L/sub A1/, and approximate values of L/sub Aeq12h/ were evaluated for each site. The results are discussed with reference to some criteria for community annoyance and means and ways to limit high-level traffic noise are suggested. (author)

Proactive Traffic Information Control in Emergency Evacuation Network

Directory of Open Access Journals (Sweden)

Zhengfeng Huang

2015-01-01

Full Text Available Traffic demand in emergency evacuation is usually too large to be effectively managed with reactive traffic information control methods. These methods adapt to the road traffic passively by publishing real-time information without consideration of the routing behavior feedback produced by evacuees. Other remedy measures have to be prepared in case of nonrecurring congestion under these methods. To use the network capacity fully to mitigate near-future evacuation traffic congestion, we propose proactive traffic information control (PTIC model. Based on the mechanism between information and routing behavior feedback, this model can change the route choice of evacuees in advance by dissipating strategic traffic information. Generally, the near-future traffic condition is difficult to accurately predict because it is uncertain in evacuation. Assume that the value of traffic information obeys certain distribution within a range, and then real-time traffic information may reflect the most-likely near-future traffic condition. Unlike the real-time information, the proactive traffic information is a selection within the range to achieve a desired level of the road network performance index (total system travel time. In the aspect of the solution algorithm, differential equilibrium decomposed optimization (D-EDO is proposed to compare with other heuristic methods. A field study on a road network around a large stadium is used to validate the PTIC.

CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response

DEFF Research Database (Denmark)

Moeller, Jesper B; Nielsen, Marianne J; Reichhardt, Martin P

2012-01-01

CD163-L1 belongs to the group B scavenger receptor cysteine-rich family of proteins, where the CD163-L1 gene arose by duplication of the gene encoding the hemoglobin scavenger receptor CD163 in late evolution. The current data demonstrate that CD163-L1 is highly expressed and colocalizes with CD163...... on large subsets of macrophages, but in contrast to CD163 the expression is low or absent in monocytes and in alveolar macrophages, glia, and Kupffer cells. The expression of CD163-L1 increases when cultured monocytes are M-CSF stimulated to macrophages, and the expression is further increased by the acute......-phase mediator IL-6 and the anti-inflammatory mediator IL-10 but is suppressed by the proinflammatory mediators IL-4, IL-13, TNF-α, and LPS/IFN-γ. Furthermore, we show that CD163-L1 is an endocytic receptor, which internalizes independently of cross-linking through a clathrin-mediated pathway. Two cytoplasmic...

Modeling Network Traffic in Wavelet Domain

Directory of Open Access Journals (Sweden)

Sheng Ma

2004-12-01

Full Text Available This work discovers that although network traffic has the complicated short- and long-range temporal dependence, the corresponding wavelet coefficients are no longer long-range dependent. Therefore, a "short-range" dependent process can be used to model network traffic in the wavelet domain. Both independent and Markov models are investigated. Theoretical analysis shows that the independent wavelet model is sufficiently accurate in terms of the buffer overflow probability for Fractional Gaussian Noise traffic. Any model, which captures additional correlations in the wavelet domain, only improves the performance marginally. The independent wavelet model is then used as a unified approach to model network traffic including VBR MPEG video and Ethernet data. The computational complexity is O(N for developing such wavelet models and generating synthesized traffic of length N, which is among the lowest attained.

Fixed Point Learning Based Intelligent Traffic Control System

Science.gov (United States)

Zongyao, Wang; Cong, Sui; Cheng, Shao

2017-10-01

Fixed point learning has become an important tool to analyse large scale distributed system such as urban traffic network. This paper presents a fixed point learning based intelligence traffic network control system. The system applies convergence property of fixed point theorem to optimize the traffic flow density. The intelligence traffic control system achieves maximum road resources usage by averaging traffic flow density among the traffic network. The intelligence traffic network control system is built based on decentralized structure and intelligence cooperation. No central control is needed to manage the system. The proposed system is simple, effective and feasible for practical use. The performance of the system is tested via theoretical proof and simulations. The results demonstrate that the system can effectively solve the traffic congestion problem and increase the vehicles average speed. It also proves that the system is flexible, reliable and feasible for practical use.

Breakdown in traffic networks fundamentals of transportation science

CERN Document Server

Kerner, Boris S

2017-01-01

This book offers a detailed investigation of breakdowns in traffic and transportation networks. It shows empirically that transitions from free flow to so-called synchronized flow, initiated by local disturbances at network bottlenecks, display a nucleation-type behavior: while small disturbances in free flow decay, larger ones grow further and lead to breakdowns at the bottlenecks. Further, it discusses in detail the significance of this nucleation effect for traffic and transportation theories, and the consequences this has for future automatic driving, traffic control, dynamic traffic assignment, and optimization in traffic and transportation networks. Starting from a large volume of field traffic data collected from various sources obtained solely through measurements in real world traffic, the author develops his insights, with an emphasis less on reviewing existing methodologies, models and theories, and more on providing a detailed analysis of empirical traffic data and drawing consequences regarding t...

System and method for traffic signal timing estimation

KAUST Repository

Dumazert, Julien; Claudel, Christian G.

2015-01-01

A method and system for estimating traffic signals. The method and system can include constructing trajectories of probe vehicles from GPS data emitted by the probe vehicles, estimating traffic signal cycles, combining the estimates, and computing the traffic signal timing by maximizing a scoring function based on the estimates. Estimating traffic signal cycles can be based on transition times of the probe vehicles starting after a traffic signal turns green.

System and method for traffic signal timing estimation

KAUST Repository

Dumazert, Julien

2015-12-30

A method and system for estimating traffic signals. The method and system can include constructing trajectories of probe vehicles from GPS data emitted by the probe vehicles, estimating traffic signal cycles, combining the estimates, and computing the traffic signal timing by maximizing a scoring function based on the estimates. Estimating traffic signal cycles can be based on transition times of the probe vehicles starting after a traffic signal turns green.

A knowledge-based system for controlling automobile traffic

Science.gov (United States)

Maravas, Alexander; Stengel, Robert F.

1994-01-01

Transportation network capacity variations arising from accidents, roadway maintenance activity, and special events as well as fluctuations in commuters' travel demands complicate traffic management. Artificial intelligence concepts and expert systems can be useful in framing policies for incident detection, congestion anticipation, and optimal traffic management. This paper examines the applicability of intelligent route guidance and control as decision aids for traffic management. Basic requirements for managing traffic are reviewed, concepts for studying traffic flow are introduced, and mathematical models for modeling traffic flow are examined. Measures for quantifying transportation network performance levels are chosen, and surveillance and control strategies are evaluated. It can be concluded that automated decision support holds great promise for aiding the efficient flow of automobile traffic over limited-access roadways, bridges, and tunnels.

The ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells.

Science.gov (United States)

Hammond, Gerald R V; Takasuga, Shunsuke; Sasaki, Takehiko; Balla, Tamas

2015-01-01

Phosphatidylinositol (3,5)-bisphosphate (PtdIns(3,5)P2) is a quantitatively minor phospholipid in eukaryotic cells that plays a fundamental role in regulating endocytic membrane traffic. Despite its clear importance for cellular function and organism physiology, mechanistic details of its biology have so far not been fully elucidated. In part, this is due to a lack of experimental tools that specifically probe for PtdIns(3,5)P2 in cells to unambiguously identify its dynamics and site(s) of action. In this study, we have evaluated a recently reported PtdIns(3,5)P2 biosensor, GFP-ML1Nx2, for its veracity as such a probe. We report that, in live cells, the localization of this biosensor to sub-cellular compartments is largely independent of PtdIns(3,5)P2, as assessed after pharmacological, chemical genetic or genomic interventions that block the lipid's synthesis. We therefore conclude that it is unwise to interpret the localization of ML1Nx2 as a true and unbiased biosensor for PtdIns(3,5)P2.

Delays at signalised intersections with exhaustive traffic control

NARCIS (Netherlands)

Boon, M.A.A.; Adan, I.J.B.F.; Winands, E.M.M.; Down, D.G.

2010-01-01

In this paper we study a traffic intersection with vehicle-actuated traffic signal control. Traffic lights stay green until all lanes within a group are emptied. Assuming general renewal arrival processes, we derive exact limiting distributions of the delays under Heavy Traffic (HT) conditions,

Delays at signalized intersections with exhaustive traffic control

NARCIS (Netherlands)

Boon, M.A.A.; Adan, I.J.B.F.; Winands, E.M.M.; Down, D.G.

2012-01-01

In this paper, we study a traffic intersection with vehicle-actuated traffic signal control. Traffic lights stay green until all lanes within a group are emptied. Assuming general renewal arrival processes, we derive exact limiting distributions of the delays under heavy traffic (HT) conditions.

Delays at signalised intersections with exhaustive traffic control

NARCIS (Netherlands)

Boon, M.A.A.; Adan, I.J.B.F.; Winands, E.M.M.; Down, D.G.

2012-01-01

In this paper, we study a traffic intersection with vehicle-actuated traffic signal control. Traffic lights stay green until all lanes within a group are emptied. Assuming general renewal arrival processes, we derive exact limiting distributions of the delays under heavy traffic (HT) conditions.

Linking network usage patterns to traffic Gaussianity fit

NARCIS (Netherlands)

de Oliveira Schmidt, R.; Sadre, R.; Melnikov, Nikolay; Schönwälder, Jürgen; Pras, Aiko

Gaussian traffic models are widely used in the domain of network traffic modeling. The central assumption is that traffic aggregates are Gaussian distributed. Due to its importance, the Gaussian character of network traffic has been extensively assessed by researchers in the past years. In 2001,

Will Automated Vehicles Negatively Impact Traffic Flow?

Directory of Open Access Journals (Sweden)

S. C. Calvert

2017-01-01

Full Text Available With low-level vehicle automation already available, there is a necessity to estimate its effects on traffic flow, especially if these could be negative. A long gradual transition will occur from manual driving to automated driving, in which many yet unknown traffic flow dynamics will be present. These effects have the potential to increasingly aid or cripple current road networks. In this contribution, we investigate these effects using an empirically calibrated and validated simulation experiment, backed up with findings from literature. We found that low-level automated vehicles in mixed traffic will initially have a small negative effect on traffic flow and road capacities. The experiment further showed that any improvement in traffic flow will only be seen at penetration rates above 70%. Also, the capacity drop appeared to be slightly higher with the presence of low-level automated vehicles. The experiment further investigated the effect of bottleneck severity and truck shares on traffic flow. Improvements to current traffic models are recommended and should include a greater detail and understanding of driver-vehicle interaction, both in conventional and in mixed traffic flow. Further research into behavioural shifts in driving is also recommended due to limited data and knowledge of these dynamics.

Fast Drawing of Traffic Sign Using Mobile Mapping System

Science.gov (United States)

Yao, Q.; Tan, B.; Huang, Y.

2016-06-01

Traffic sign provides road users with the specified instruction and information to enhance traffic safety. Automatic detection of traffic sign is important for navigation, autonomous driving, transportation asset management, etc. With the advance of laser and imaging sensors, Mobile Mapping System (MMS) becomes widely used in transportation agencies to map the transportation infrastructure. Although many algorithms of traffic sign detection are developed in the literature, they are still a tradeoff between the detection speed and accuracy, especially for the large-scale mobile mapping of both the rural and urban roads. This paper is motivated to efficiently survey traffic signs while mapping the road network and the roadside landscape. Inspired by the manual delineation of traffic sign, a drawing strategy is proposed to quickly approximate the boundary of traffic sign. Both the shape and color prior of the traffic sign are simultaneously involved during the drawing process. The most common speed-limit sign circle and the statistic color model of traffic sign are studied in this paper. Anchor points of traffic sign edge are located with the local maxima of color and gradient difference. Starting with the anchor points, contour of traffic sign is drawn smartly along the most significant direction of color and intensity consistency. The drawing process is also constrained by the curvature feature of the traffic sign circle. The drawing of linear growth is discarded immediately if it fails to form an arc over some steps. The Kalman filter principle is adopted to predict the temporal context of traffic sign. Based on the estimated point,we can predict and double check the traffic sign in consecutive frames.The event probability of having a traffic sign over the consecutive observations is compared with the null hypothesis of no perceptible traffic sign. The temporally salient traffic sign is then detected statistically and automatically as the rare event of having a

Fine-Tuning ADAS Algorithm Parameters for Optimizing Traffic ...

Science.gov (United States)

With the development of the Connected Vehicle technology that facilitates wirelessly communication among vehicles and road-side infrastructure, the Advanced Driver Assistance Systems (ADAS) can be adopted as an effective tool for accelerating traffic safety and mobility optimization at various highway facilities. To this end, the traffic management centers identify the optimal ADAS algorithm parameter set that enables the maximum improvement of the traffic safety and mobility performance, and broadcast the optimal parameter set wirelessly to individual ADAS-equipped vehicles. After adopting the optimal parameter set, the ADAS-equipped drivers become active agents in the traffic stream that work collectively and consistently to prevent traffic conflicts, lower the intensity of traffic disturbances, and suppress the development of traffic oscillations into heavy traffic jams. Successful implementation of this objective requires the analysis capability of capturing the impact of the ADAS on driving behaviors, and measuring traffic safety and mobility performance under the influence of the ADAS. To address this challenge, this research proposes a synthetic methodology that incorporates the ADAS-affected driving behavior modeling and state-of-the-art microscopic traffic flow modeling into a virtually simulated environment. Building on such an environment, the optimal ADAS algorithm parameter set is identified through an optimization programming framework to enable th

A First Look at Modern Enterprise Traffic

Energy Technology Data Exchange (ETDEWEB)

Pang, Ruoming; Mark Allman, Mark; Bennett, Mike; Lee, Jason; Paxson, Vern; Tierney, Brian

2005-06-01

While wide-area Internet traffic has been heavily studied for many years, the characteristics of traffic inside Internet enterprises remain almost wholly unexplored. Nearly all of the studies of enterprise traffic available in the literature are well over a decade old and focus on individual LANs rather than whole sites. In this paper we present a broad overview of internal enterprise traffic recorded at a medium-sized site. The packet traces span more than 100 hours, over which activity from a total of several thousand internal hosts appears. This wealth of data--which we are publicly releasing in anonymized form--spans a wide range of dimensions. While we cannot form general conclusions using data from a single site, and clearly this sort of data merits additional in-depth study in a number of ways, in this work we endeavor to characterize a number of the most salient aspects of the traffic. Our goal is to provide a first sense of ways in which modern enterprise traffic is similar to wide-area Internet traffic, and ways in which it is quite different.

Rail-induced Traffic in China

Directory of Open Access Journals (Sweden)

Nan He

2017-11-01

Full Text Available The rapid development of China’s railway has exerted an enormous influence on the intercity passenger transport structure in recent years. However, it has not satisfied the passengers’ travel demand due to induced traffic. This paper is committed to solving such issue, with the aim of satisfying the current travel demand, and of anticipating the demand of the predicted traffic growth over the next 20 to 30 years. The paper has considered the increase in rail passenger kilometres caused by the growth of rail kilometres as rail-induced traffic. Based on the concept and former research of induced traffic, the panel data of 26 provinces and 3 municipalities of China between the year 2000 and 2014 were collected, and the elasticity models (including elasticity-based model, distributed lag model, high-speed rail (HSR elasticity model and rail efficiency model have been constructed. The results show the importance of model formation incorporation of rail-induced traffic. It is better to get the correct value in divided zones with different train frequencies or incorporation rail efficiency in cities or provinces. The lag time and rail types also need to be considered. In summary, the results analysis not only confirms the existence of rail-induced traffic, but also provides substantial recommendations to train operation planning.

Classification of Automated Search Traffic

Science.gov (United States)

Buehrer, Greg; Stokes, Jack W.; Chellapilla, Kumar; Platt, John C.

As web search providers seek to improve both relevance and response times, they are challenged by the ever-increasing tax of automated search query traffic. Third party systems interact with search engines for a variety of reasons, such as monitoring a web site’s rank, augmenting online games, or possibly to maliciously alter click-through rates. In this paper, we investigate automated traffic (sometimes referred to as bot traffic) in the query stream of a large search engine provider. We define automated traffic as any search query not generated by a human in real time. We first provide examples of different categories of query logs generated by automated means. We then develop many different features that distinguish between queries generated by people searching for information, and those generated by automated processes. We categorize these features into two classes, either an interpretation of the physical model of human interactions, or as behavioral patterns of automated interactions. Using the these detection features, we next classify the query stream using multiple binary classifiers. In addition, a multiclass classifier is then developed to identify subclasses of both normal and automated traffic. An active learning algorithm is used to suggest which user sessions to label to improve the accuracy of the multiclass classifier, while also seeking to discover new classes of automated traffic. Performance analysis are then provided. Finally, the multiclass classifier is used to predict the subclass distribution for the search query stream.

11th Traffic and Granular Flow Conference

CERN Document Server

Daamen, Winnie

2016-01-01

The Conference on Traffic and Granular Flow brings together international researchers from different fields ranging from physics to computer science and engineering to discuss the latest developments in traffic-related systems. Originally conceived to facilitate new ideas by considering the similarities of traffic and granular flow, TGF'15, organised by Delft University of Technology, now covers a broad range of topics related to driven particle and transport systems. Besides the classical topics of granular flow and highway traffic, its scope includes data transport (Internet traffic), pedestrian and evacuation dynamics, intercellular transport, swarm behaviour and the collective dynamics of other biological systems. Recent advances in modelling, computer simulation and phenomenology are presented, and prospects for applications, for example to traffic control, are discussed. The conference explores the interrelations between the above-mentioned fields and offers the opportunity to stimulate interdisciplinar...

Texas traffic thermostat software tool.

Science.gov (United States)

2013-04-01

The traffic thermostat decision tool is built to help guide the user through a logical, step-wise, process of examining potential changes to their Manage Lane/toll facility. : **NOTE: Project Title: Application of the Traffic Thermostat Framework. Ap...

Texas traffic thermostat marketing package.

Science.gov (United States)

2013-04-01

The traffic thermostat decision tool is built to help guide the user through a logical, step-wise, process of examining potential changes to their Manage Lane/toll facility. : **NOTE: Project Title: Application of the Traffic Thermostat Framework. Ap...

[Distribution of and changes in Danish traffic deaths].

Science.gov (United States)

Bjerre, Johannes; Kirkebjerg, Peer Gregersen; Larsen, Lars Binderup

2006-05-01

Traffic accidents were the primary cause of death for Danes aged 15 to 24 years in 1999; per million inhabitants, that figure was 62% higher than in Great Britain. Reduction to the level in Great Britain would have reduced the number killed in traffic accidents in Denmark in 2002 from 465 to 289. The data used are from StatBank Denmark, the Danish Road Directorate and the Danish Transport Research Institute. The number of traffic deaths per billion kilometers driven was 57% higher in 1994 than in 2001. Those aged 65 and over had the largest decrease, with 67% fewer traffic deaths. Per billion kilometers driven, rural roads had around twice the number of traffic deaths as city streets and motorways. The geographic distribution showed few traffic deaths in the capital, Copenhagen, while the rest of the country had up to twice the number per 100,000 inhabitants from 1997 to 2002. Car drivers were well protected by seat belts, while people who were walking or on a motorcycle had high casualty rates per billion kilometers driven. 29% of the traffic deaths in Denmark in 2002 were registered as alcohol-related, while only 1% of drivers overall were influenced by alcohol. Men had twice the risk of traffic death compared with women per kilometer driven. Men were convicted in 93% of cases involving illegal blood alcohol level and 84% of cases involving other traffic offences. The greatest potential for reduction of traffic deaths seems to be traffic behaviour; females' behaviour, with rare drunk driving and few convictions for traffic offences, seems rational. If all drivers adhered to women's traffic behaviour, the number of road deaths in 1999 could have been reduced by 169, equivalent to 30%.

Analysis of Block OMP using Block RIP

OpenAIRE

Wang, Jun; Li, Gang; Zhang, Hao; Wang, Xiqin

2011-01-01

Orthogonal matching pursuit (OMP) is a canonical greedy algorithm for sparse signal reconstruction. When the signal of interest is block sparse, i.e., it has nonzero coefficients occurring in clusters, the block version of OMP algorithm (i.e., Block OMP) outperforms the conventional OMP. In this paper, we demonstrate that a new notion of block restricted isometry property (Block RIP), which is less stringent than standard restricted isometry property (RIP), can be used for a very straightforw...

Host cell virus entry mediated by Australian bat lyssavirus G envelope glycoprotein occurs through a clathrin-mediated endocytic pathway that requires actin and Rab5.

Science.gov (United States)

Weir, Dawn L; Laing, Eric D; Smith, Ina L; Wang, Lin-Fa; Broder, Christopher C

2014-02-27

Australian bat lyssavirus (ABLV), a rhabdovirus of the genus Lyssavirus which circulates in both pteropid fruit bats and insectivorous bats in mainland Australia, has caused three fatal human infections, the most recent in February 2013, manifested as acute neurological disease indistinguishable from clinical rabies. Rhabdoviruses infect host cells through receptor-mediated endocytosis and subsequent pH-dependent fusion mediated by their single envelope glycoprotein (G), but the specific host factors and pathways involved in ABLV entry have not been determined. ABLV internalization into HEK293T cells was examined using maxGFP-encoding recombinant vesicular stomatitis viruses (rVSV) that express ABLV G glycoproteins. A combination of chemical and molecular approaches was used to investigate the contribution of different endocytic pathways to ABLV entry. Dominant negative Rab GTPases were used to identify the endosomal compartment utilized by ABLV to gain entry into the host cell cytosol. Here we show that ABLV G-mediated entry into HEK293T cells was significantly inhibited by the dynamin-specific inhibitor dynasore, chlorpromazine, a drug that blocks clathrin-mediated endocytosis, and the actin depolymerizing drug latrunculin B. Over expression of dominant negative mutants of Eps15 and Rab5 also significantly reduced ABLV G-mediated entry into HEK293T cells. Chemical inhibitors of caveolae-dependent endocytosis and macropinocytosis and dominant negative mutants of Rab7 and Rab11 had no effect on ABLV entry. The predominant pathway utilized by ABLV for internalization into HEK293T cells is clathrin-and actin-dependent. The requirement of Rab5 for productive infection indicates that ABLV G-mediated fusion occurs within the early endosome compartment.

Assessment of Traffic Noise Impacts

DEFF Research Database (Denmark)

Rich, Jeppe Husted; Nielsen, Otto Anker

2004-01-01

A steady growth in traffic intensities in most urban areas throughout the world has forced planners and politicians to seriously consider the resulting environmental impact, such as traffic noise, accidents and air pollution. The assessment of such negative factors is needed in order to reveal...... the true social benefit of infrastructure plans. The paper presents a noise assessment model for the Copenhagen region, which brings together GIS technology and non-linear hedonic regression models to reveal the implicit costs of traffic noise measured as the marginal percentage loss in property values...

National guidelines for traffic calming

CSIR Research Space (South Africa)

Schermers, G

1998-03-01

Full Text Available and provides a policy framework on traffic calming. It also describes the administrative and management procedures required to meet policy objectives in the implementation and monitoring of traffic calming in urban areas. Related legal requirements, liability...

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

Science.gov (United States)

Abes, Saïd; Moulton, Hong M; Clair, Philippe; Prevot, Paul; Youngblood, Derek S; Wu, Rebecca P; Iversen, Patrick L; Lebleu, Bernard

2006-12-01

The efficient and non-toxic nuclear delivery of steric-block oligonucleotides (ON) is a prerequisite for therapeutic strategies involving splice correction or exon skipping. Cationic cell penetrating peptides (CPPs) have given rise to much interest for the intracellular delivery of biomolecules, but their efficiency in promoting cytoplasmic or nuclear delivery of oligonucleotides has been hampered by endocytic sequestration and subsequent degradation of most internalized material in endocytic compartments. In the present study, we compared the splice correction activity of three different CPPs conjugated to PMO(705), a steric-block ON targeted against the mutated splicing site of human beta-globin pre-mRNA in the HeLa pLuc705 splice correction model. In contrast to Tat48-60 (Tat) and oligoarginine (R(9)F(2)) PMO(705) conjugates, the 6-aminohexanoic-spaced oligoarginine (R-Ahx-R)(4)-PMO(705) conjugate was able to promote an efficient splice correction in the absence of endosomolytic agents. Our mechanistic investigations about its uptake mechanisms lead to the conclusion that these three vectors are internalized using the same endocytic route involving proteoglycans, but that the (R-Ahx-R)(4)-PMO(705) conjugate has the unique ability to escape from lysosomial fate and to access to the nuclear compartment. This vector, which has displays an extremely low cytotoxicity, the ability to function without chloroquine adjunction and in the presence of serum proteins. It thus offers a promising lead for the development of vectors able to enhance the delivery of therapeutic steric-block ON in clinically relevant models.

The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together.

Science.gov (United States)

Bäck, Nils; Kanerva, Kristiina; Kurutihalli, Vishwanatha; Yanik, Andrew; Ikonen, Elina; Mains, Richard E; Eipper, Betty A

2017-08-01

Peptidylglycine α-amidating monooxygenase (PAM) is highly expressed in neurons and endocrine cells, where it catalyzes one of the final steps in the biosynthesis of bioactive peptides. PAM is also expressed in unicellular organisms such as Chlamydomonas reinhardtii, which do not store peptides in secretory granules. As for other granule membrane proteins, PAM is retrieved from the cell surface and returned to the trans-Golgi network. This pathway involves regulated entry of PAM into multivesicular body intralumenal vesicles (ILVs). The aim of this study was defining the endocytic pathways utilized by PAM in cells that do not store secretory products in granules. Using stably transfected HEK293 cells, endocytic trafficking of PAM was compared to that of the mannose 6-phosphate (MPR) and EGF (EGFR) receptors, established markers for the endosome to trans-Golgi network and degradative pathways, respectively. As in neuroendocrine cells, PAM internalized by HEK293 cells accumulated in the trans-Golgi network. Based on surface biotinylation, >70% of the PAM on the cell surface was recovered intact after a 4h chase and soluble, bifunctional PAM was produced. Endosomes containing PAM generally contained both EGFR and MPR and ultrastructural analysis confirmed that all three cargos accumulated in ILVs. PAM containing multivesicular bodies made frequent dynamic tubular contacts with younger and older multivesicular bodies. Frequent dynamic contacts were observed between lysosomes and PAM containing early endosomes and multivesicular bodies. The ancient ability of PAM to localize to ciliary membranes, which release bioactive ectosomes, may be related to its ability to accumulate in ILVs and exosomes. Copyright © 2017 Elsevier GmbH. All rights reserved.

Marine Traffic Optimization Using Petri Net and Genetic Algorithm

Directory of Open Access Journals (Sweden)

Anita Gudelj

2012-11-01

Full Text Available The paper deals with the traffic control and job optimization in the marine canal system. The moving of vessels can be described as a set of discrete events and states. Some of these states can be undesirable such as conflicts and deadlocks. It is necessary to apply adequate control policy to avoid deadlocks and blocks the vessels’ moving only in the case of dangerous situation. This paper addresses the use of Petri net as modelling and scheduling tool in this context. To find better solutions the authors propose the integration of Petri net with a genetic algorithm. Also, a matrix based formal method is proposed for analyzing discrete event dynamic system (DEDS. The algorithm is developed to deal with multi-project, multi-constrained scheduling problem with shared resources. It is verified by a computer simulation using MATLAB environment.

Indicators of residential traffic exposure: Modelled NOX, traffic proximity, and self-reported exposure in RHINE III

Science.gov (United States)

Carlsen, Hanne Krage; Bäck, Erik; Eneroth, Kristina; Gislason, Thorarinn; Holm, Mathias; Janson, Christer; Jensen, Steen Solvang; Johannessen, Ane; Kaasik, Marko; Modig, Lars; Segersson, David; Sigsgaard, Torben; Forsberg, Bertil; Olsson, David; Orru, Hans

2017-10-01

Few studies have investigated associations between self-reported and modelled exposure to traffic pollution. The objective of this study was to examine correlations between self-reported traffic exposure and modelled (a) NOX and (b) traffic proximity in seven different northern European cities; Aarhus (Denmark), Bergen (Norway), Gothenburg, Umeå, and Uppsala (Sweden), Reykjavik (Iceland), and Tartu (Estonia). We analysed data from the RHINE III (Respiratory Health in Northern Europe, http://www.rhine.nu)

Road traffic impact on urban water quality: a step towards integrated traffic, air and stormwater modelling.

Science.gov (United States)

Fallah Shorshani, Masoud; Bonhomme, Céline; Petrucci, Guido; André, Michel; Seigneur, Christian

2014-04-01

Methods for simulating air pollution due to road traffic and the associated effects on stormwater runoff quality in an urban environment are examined with particular emphasis on the integration of the various simulation models into a consistent modelling chain. To that end, the models for traffic, pollutant emissions, atmospheric dispersion and deposition, and stormwater contamination are reviewed. The present study focuses on the implementation of a modelling chain for an actual urban case study, which is the contamination of water runoff by cadmium (Cd), lead (Pb), and zinc (Zn) in the Grigny urban catchment near Paris, France. First, traffic emissions are calculated with traffic inputs using the COPERT4 methodology. Next, the atmospheric dispersion of pollutants is simulated with the Polyphemus line source model and pollutant deposition fluxes in different subcatchment areas are calculated. Finally, the SWMM water quantity and quality model is used to estimate the concentrations of pollutants in stormwater runoff. The simulation results are compared to mass flow rates and concentrations of Cd, Pb and Zn measured at the catchment outlet. The contribution of local traffic to stormwater contamination is estimated to be significant for Pb and, to a lesser extent, for Zn and Cd; however, Pb is most likely overestimated due to outdated emissions factors. The results demonstrate the importance of treating distributed traffic emissions from major roadways explicitly since the impact of these sources on concentrations in the catchment outlet is underestimated when those traffic emissions are spatially averaged over the catchment area.

IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling.

Science.gov (United States)

Yoneyama, Yosuke; Lanzerstorfer, Peter; Niwa, Hideaki; Umehara, Takashi; Shibano, Takashi; Yokoyama, Shigeyuki; Chida, Kazuhiro; Weghuber, Julian; Hakuno, Fumihiko; Takahashi, Shin-Ichiro

2018-04-11

Insulin-like growth factor-I receptor (IGF-IR) preferentially regulates the long-term IGF activities including growth and metabolism. Kinetics of ligand-dependent IGF-IR endocytosis determines how IGF induces such downstream signaling outputs. Here, we find that the insulin receptor substrate (IRS)-1 modulates how long ligand-activated IGF-IR remains at the cell surface before undergoing endocytosis in mammalian cells. IRS-1 interacts with the clathrin adaptor complex AP2. IRS-1, but not an AP2-binding-deficient mutant, delays AP2-mediated IGF-IR endocytosis after the ligand stimulation. Mechanistically, IRS-1 inhibits the recruitment of IGF-IR into clathrin-coated structures; for this reason, IGF-IR avoids rapid endocytosis and prolongs its activity on the cell surface. Accelerating IGF-IR endocytosis via IRS-1 depletion induces the shift from sustained to transient Akt activation and augments FoxO-mediated transcription. Our study establishes a new role for IRS-1 as an endocytic regulator of IGF-IR that ensures sustained IGF bioactivity, independent of its classic role as an adaptor in IGF-IR signaling. © 2018, Yoneyama et al.

32 CFR 636.13 - Traffic accident investigation reports.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Traffic accident investigation reports. 636.13... Stewart, Georgia § 636.13 Traffic accident investigation reports. In addition to the requirements in § 634... record traffic accident investigations on DA Form 3946 (Military Police Traffic Accident Report) and DA...

31 CFR 595.301 - Blocked account; blocked property.

Science.gov (United States)

2010-07-01

... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TERRORISM SANCTIONS REGULATIONS General Definitions § 595.301 Blocked account; blocked property. The terms blocked account and blocked...

Traffic-days at Aalborg University 1996. Conference report 1

International Nuclear Information System (INIS)

Lahrmann, H.; Hald Pedersen, L.

1996-01-01

Volume 1 (of two volumes) of the report on the conference 'Traffic days '96' held at Aalborg University (Denmark) on August 19-20, 1996, contains the papers presented at the conference under the general headings of the role of the car in the transport system of the future, traffic models, urban planning and traffic, traffic control, traffic and the urban environment, traffic and emissions, freight transport and railways. (EG)

Traffic Flow Theory - A State-of-the-Art Report: Revised Monograph on Traffic Flow Theory

Science.gov (United States)

2002-04-13

This publication is an update and expansion of the Transportation Research Board (TRB) Special Report 165, "Traffic Flow Theory," published in 1975. This updating was undertaken on recommendation of the TRB's Committee on Traffic Flow Theory and Char...

The establishment of polarized membrane traffic in Xenopus laevis embryos.

Science.gov (United States)

Roberts, S J; Leaf, D S; Moore, H P; Gerhart, J C

1992-09-01

Delineation of apical and basolateral membrane domains is a critical step in the epithelialization of the outer layer of cells in the embryo. We have examined the initiation of polarized membrane traffic in Xenopus and show that membrane traffic is not polarized in oocytes but polarized membrane domains appear at first cleavage. The following proteins encoded by injected RNA transcripts were used as markers to monitor membrane traffic: (a) VSV G, a transmembrane glycoprotein preferentially inserted into the basolateral surface of polarized epithelial cells; (b) GThy-1, a fusion protein of VSV G and Thy-1 that is localized to the apical domains of polarized epithelial cells; and (c) prolactin, a peptide hormone that is not polarly secreted. In immature oocytes, there is no polarity in the expression of VSV G or GThy-1, as shown by the constitutive expression of both proteins at the surface in the animal and vegetal hemispheres. At meiotic maturation, membrane traffic to the surface is blocked; the plasma membrane no longer accepts the vesicles synthesized by the oocyte (Leaf, D. L., S. J. Roberts, J. C. Gerhart, and H.-P. Moore. 1990. Dev. Biol. 141:1-12). When RNA transcripts are injected after fertilization, VSV G is expressed only in the internal cleavage membranes (basolateral orientation) and is excluded from the outer surface (apical orientation, original oocyte membrane). In contrast, GThy-1 and prolactin, when expressed in embryos, are inserted or released at both the outer membrane derived from the oocyte and the inner cleavage membranes. Furthermore, not all of the cleavage membrane comes from an embryonic pool of vesicles--some of the cleavage membrane comes from vesicles synthesized during oogenesis. Using prolactin as a marker, we found that a subset of vesicles synthesized during oogenesis was only released after fertilization. However, while embryonic prolactin was secreted from both apical and basolateral surfaces, the secretion of oogenic prolactin

Alterations in endocytic protein expression with increasing age in the transgenic APP695 V717I London mouse model of amyloid pathology – implications for Alzheimer’s disease

OpenAIRE

Thomas, R. S.; Alsaqatia, M. ed; Bice, J. S.; Hvoslef-Eide, M.; Good, M. A.; Kidd, E. J.

2017-01-01

A major risk factor for the development of Alzheimer’s disease is increasing age but the reason behind this association has not been identified. It is thought that the changes in endocytosis seen in Alzheimer’s disease patients are causal for this condition. Thus we hypothesised that the increased risk of developing Alzheimer’s disease associated with ageing may be due to changes in endocytosis. We investigated using Western blotting whether the expression of endocytic proteins involved in cl...

Approaches for Intelligent Traffic System: A Survey

OpenAIRE

Pratishtha Gupta; G.N Purohit; Amrita Dadhich

2012-01-01

This survey presents various approaches for intelligent traffic systems. The potential research fields in which Intelligent Traffic System emerges as an important application area are highlighted andvarious issues have been identified which need to be handled while developing such a system for an urban area, where an efficient traffic management has become the need of hour.A model is also proposed capable of managing intelligent traffic system using CCTV cameras and WAN. The proposed model wi...

Physics of traffic gridlock in a city

OpenAIRE

Kerner, Boris S.

2011-01-01

Based of simulations of a stochastic three-phase traffic flow model, we reveal that at a signalized city intersection under small link inflow rates at which a vehicle queue developed during the red phase of light signal dissolves fully during the green phase, i.e., no traffic gridlock should be expected, nevertheless, traffic breakdown with the subsequent city gridlock occurs with some probability after a random time delay. This traffic breakdown is initiated by a first-order phase transition...

Traffic flow dynamics. Data, models and simulation

Energy Technology Data Exchange (ETDEWEB)

Treiber, Martin [Technische Univ. Dresden (Germany). Inst. fuer Wirtschaft und Verkehr; Kesting, Arne [TomTom Development Germany GmbH, Berlin (Germany)

2013-07-01

First comprehensive textbook of this fascinating interdisciplinary topic which explains advances in a way that it is easily accessible to engineering, physics and math students. Presents practical applications of traffic theory such as driving behavior, stability analysis, stop-and-go waves, and travel time estimation. Presents the topic in a novel and systematic way by addressing both microscopic and macroscopic models with a focus on traffic instabilities. Revised and extended edition of the German textbook ''Verkehrsdynamik und -simulation''. This textbook provides a comprehensive and instructive coverage of vehicular traffic flow dynamics and modeling. It makes this fascinating interdisciplinary topic, which to date was only documented in parts by specialized monographs, accessible to a broad readership. Numerous figures and problems with solutions help the reader to quickly understand and practice the presented concepts. This book is targeted at students of physics and traffic engineering and, more generally, also at students and professionals in computer science, mathematics, and interdisciplinary topics. It also offers material for project work in programming and simulation at college and university level. The main part, after presenting different categories of traffic data, is devoted to a mathematical description of the dynamics of traffic flow, covering macroscopic models which describe traffic in terms of density, as well as microscopic many-particle models in which each particle corresponds to a vehicle and its driver. Focus chapters on traffic instabilities and model calibration/validation present these topics in a novel and systematic way. Finally, the theoretical framework is shown at work in selected applications such as traffic-state and travel-time estimation, intelligent transportation systems, traffic operations management, and a detailed physics-based model for fuel consumption and emissions.

CATS-based Air Traffic Controller Agents

Science.gov (United States)

Callantine, Todd J.

2002-01-01

This report describes intelligent agents that function as air traffic controllers. Each agent controls traffic in a single sector in real time; agents controlling traffic in adjoining sectors can coordinate to manage an arrival flow across a given meter fix. The purpose of this research is threefold. First, it seeks to study the design of agents for controlling complex systems. In particular, it investigates agent planning and reactive control functionality in a dynamic environment in which a variety perceptual and decision making skills play a central role. It examines how heuristic rules can be applied to model planning and decision making skills, rather than attempting to apply optimization methods. Thus, the research attempts to develop intelligent agents that provide an approximation of human air traffic controller behavior that, while not based on an explicit cognitive model, does produce task performance consistent with the way human air traffic controllers operate. Second, this research sought to extend previous research on using the Crew Activity Tracking System (CATS) as the basis for intelligent agents. The agents use a high-level model of air traffic controller activities to structure the control task. To execute an activity in the CATS model, according to the current task context, the agents reference a 'skill library' and 'control rules' that in turn execute the pattern recognition, planning, and decision-making required to perform the activity. Applying the skills enables the agents to modify their representation of the current control situation (i.e., the 'flick' or 'picture'). The updated representation supports the next activity in a cycle of action that, taken as a whole, simulates air traffic controller behavior. A third, practical motivation for this research is to use intelligent agents to support evaluation of new air traffic control (ATC) methods to support new Air Traffic Management (ATM) concepts. Current approaches that use large, human

Environmental pollution of lead in traffic air and blood of traffic policemen in Khartoum State, Sudan.

Science.gov (United States)

Rahama, Salah M; Khider, Hiba E; Mohamed, Sitt Nour H; Abuelmaali, Sara A; Elaagip, Arwa H

2011-06-01

A cross sectional study was conducted in Khartoum State. A total of 45 males' traffic policemen were divided into two groups according to exposure to car exhaust; n=30 taken as exposed group, n=15 taken as controls, who were not exposed to car exhaust. The study was conducted to determine lead concentrations in traffic ambient air, to determine lead levels in blood of traffic policemen, and to evaluate the effect of exposure to car exhaust on traffic policemen during January 2009. The level of lead in ambient air was determined in 14 locations which were taken randomly at the intersections and entrances to the bridges using personal sampler "Cassella, U.K". The blood samples of all policemen were analyzed by atomic absorption Spectrophotometer to determine lead levels. A questionnaire was designed to assess the adverse health effects on the traffic policemen. The degree of environmental lead pollution in traffic ambient air was found to be 0.1937 +/- 0.1768 mg/m3 with range between 0.000-0.5166 mg/m3. In seven locations out of fourteen locations lead concentrations were 0.1940 and 0.5166 above the permissible level of 0.15 mg/m3 permitted internationally. Blood lead levels on traffic policemen (exposed and control groups) were found to be 2.4691 +/- 1.4065 microg/100 ml and 0.3944 +/- 1.2471 microg/100 ml respectively and there is no significant differences between the two groups where using SPSS program. A questionnaire findings were: average age mean of 35.9 +/- 7.7 years, 47.48% worked for periods of more than 20 years, 74.19% did not work before joining the traffic police, 51.6% of them recognized traffic air pollution as a problem of high level, 45.2% of them estimated it as medium, and 3.2% as low. As habits 38.71% were smokers, and for health complaints, 61.29% have various complaints of headache, fatigue, abdominal, hypertension and anemia. All these symptoms have a close relationship with lead poisoning. When we compared the results of age groups and work

Reliable Path Selection Problem in Uncertain Traffic Network after Natural Disaster

Directory of Open Access Journals (Sweden)

Jing Wang

2013-01-01

Full Text Available After natural disaster, especially for large-scale disasters and affected areas, vast relief materials are often needed. In the meantime, the traffic networks are always of uncertainty because of the disaster. In this paper, we assume that the edges in the network are either connected or blocked, and the connection probability of each edge is known. In order to ensure the arrival of these supplies at the affected areas, it is important to select a reliable path. A reliable path selection model is formulated, and two algorithms for solving this model are presented. Then, adjustable reliable path selection model is proposed when the edge of the selected reliable path is broken. And the corresponding algorithms are shown to be efficient both theoretically and numerically.

FAST DRAWING OF TRAFFIC SIGN USING MOBILE MAPPING SYSTEM

Directory of Open Access Journals (Sweden)

Q. Yao

2016-06-01

Full Text Available Traffic sign provides road users with the specified instruction and information to enhance traffic safety. Automatic detection of traffic sign is important for navigation, autonomous driving, transportation asset management, etc. With the advance of laser and imaging sensors, Mobile Mapping System (MMS becomes widely used in transportation agencies to map the transportation infrastructure. Although many algorithms of traffic sign detection are developed in the literature, they are still a tradeoff between the detection speed and accuracy, especially for the large-scale mobile mapping of both the rural and urban roads. This paper is motivated to efficiently survey traffic signs while mapping the road network and the roadside landscape. Inspired by the manual delineation of traffic sign, a drawing strategy is proposed to quickly approximate the boundary of traffic sign. Both the shape and color prior of the traffic sign are simultaneously involved during the drawing process. The most common speed-limit sign circle and the statistic color model of traffic sign are studied in this paper. Anchor points of traffic sign edge are located with the local maxima of color and gradient difference. Starting with the anchor points, contour of traffic sign is drawn smartly along the most significant direction of color and intensity consistency. The drawing process is also constrained by the curvature feature of the traffic sign circle. The drawing of linear growth is discarded immediately if it fails to form an arc over some steps. The Kalman filter principle is adopted to predict the temporal context of traffic sign. Based on the estimated point,we can predict and double check the traffic sign in consecutive frames.The event probability of having a traffic sign over the consecutive observations is compared with the null hypothesis of no perceptible traffic sign. The temporally salient traffic sign is then detected statistically and automatically as the rare

Online traffic flow model applying dynamic flow-density relation

International Nuclear Information System (INIS)

Kim, Y.

2002-01-01

This dissertation describes a new approach of the online traffic flow modelling based on the hydrodynamic traffic flow model and an online process to adapt the flow-density relation dynamically. The new modelling approach was tested based on the real traffic situations in various homogeneous motorway sections and a motorway section with ramps and gave encouraging simulation results. This work is composed of two parts: first the analysis of traffic flow characteristics and second the development of a new online traffic flow model applying these characteristics. For homogeneous motorway sections traffic flow is classified into six different traffic states with different characteristics. Delimitation criteria were developed to separate these states. The hysteresis phenomena were analysed during the transitions between these traffic states. The traffic states and the transitions are represented on a states diagram with the flow axis and the density axis. For motorway sections with ramps the complicated traffic flow is simplified and classified into three traffic states depending on the propagation of congestion. The traffic states are represented on a phase diagram with the upstream demand axis and the interaction strength axis which was defined in this research. The states diagram and the phase diagram provide a basis for the development of the dynamic flow-density relation. The first-order hydrodynamic traffic flow model was programmed according to the cell-transmission scheme extended by the modification of flow dependent sending/receiving functions, the classification of cells and the determination strategy for the flow-density relation in the cells. The unreasonable results of macroscopic traffic flow models, which may occur in the first and last cells in certain conditions are alleviated by applying buffer cells between the traffic data and the model. The sending/receiving functions of the cells are determined dynamically based on the classification of the

Survivable Impairment-Aware Traffic Grooming

NARCIS (Netherlands)

Beshir, A.; Nuijts, R.; Malhotra, R.; Kuipers, F.

2011-01-01

Traffic grooming allows efficient utilization of network capacity by aggregating several independent traffic streams into a wavelength. In addition, survivability and impairment-awareness (i.e., taking into account the effect of physical impairments) are two important issues that have gained a lot

Design and Operational Evaluation of the Traffic Management Advisor at the Ft. Worth Air Route Traffic Control Center

Science.gov (United States)

Swenson, Harry N.; Vincent, Danny; Tobias, Leonard (Technical Monitor)

1997-01-01

NASA and the FAA have designed and developed and an automation tool known as the Traffic Management Advisor (TMA). The system was operationally evaluated at the Ft. Worth Air Route Traffic Control Center (ARTCC). The TMA is a time-based strategic planning tool that provides Traffic Management Coordinators and En Route Air Traffic Controllers the ability to efficiently optimize the capacity of a demand impacted airport. The TMA consists of trajectory prediction, constraint-based runway scheduling, traffic flow visualization and controllers advisories. The TMA was used and operationally evaluated for forty-one rush traffic periods during a one month period in the Summer of 1996. The evaluations included all shifts of air traffic operations as well as periods of inclement weather. Performance data was collected for engineering and human factor analysis and compared with similar operations without the TMA. The engineering data indicates that the operations with the TMA show a one to two minute per aircraft delay reduction during rush periods. The human factor data indicate a perceived reduction in en route controller workload as well as an increase in job satisfaction. Upon completion of the evaluation, the TMA has become part of the normal operations at the Ft. Worth ARTCC.

Nerve Blocks

Science.gov (United States)

... News Physician Resources Professions Site Index A-Z Nerve Blocks A nerve block is an injection to ... the limitations of Nerve Block? What is a Nerve Block? A nerve block is an anesthetic and/ ...

Scalable data-driven short-term traffic prediction

NARCIS (Netherlands)

Friso, K.; Wismans, L. J.J.; Tijink, M. B.

2017-01-01

Short-term traffic prediction has a lot of potential for traffic management. However, most research has traditionally focused on either traffic models-which do not scale very well to large networks, computationally-or on data-driven methods for freeways, leaving out urban arterials completely. Urban

Phase diagram distortion from traffic parameter averaging.

NARCIS (Netherlands)

Stipdonk, H. Toorenburg, J. van & Postema, M.

2010-01-01

Motorway traffic congestion is a major bottleneck for economic growth. Therefore, research of traffic behaviour is carried out in many countries. Although well describing the undersaturated free flow phase as an almost straight line in a (k,q)-phase diagram, congested traffic observations and

32 CFR 634.24 - Traffic planning and codes.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Traffic planning and codes. 634.24 Section 634.24 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.24 Traffic planning and codes. (a) Safe and efficient...

An LTE implementation based on a road traffic density model

OpenAIRE

Attaullah, Muhammad

2013-01-01

The increase in vehicular traffic has created new challenges in determining the behavior of performance of data and safety measures in traffic. Hence, traffic signals on intersection used as cost effective and time saving tools for traffic management in urban areas. But on the other hand the signalized intersections in congested urban areas are the key source of high traffic density and slow traffic. High traffic density causes the slow network traffic data rate between vehicle to vehicle and...

Intelligent driving in traffic systems with partial lane discipline

Science.gov (United States)

Assadi, Hamid; Emmerich, Heike

2013-04-01

It is a most common notion in traffic theory that driving in lanes and keeping lane changes to a minimum leads to smooth and laminar traffic flow, and hence to increased traffic capacity. On the other hand, there exist persistent vehicular traffic systems that are characterised by habitual disregarding of lane markings, and partial or complete loss of laminar traffic flow. Here, we explore the stability of such systems through a microscopic traffic flow model, where the degree of lane-discipline is taken as a variable, represented by the fraction of drivers that disregard lane markings completely. The results show that lane-free traffic may win over completely ordered traffic at high densities, and that partially ordered traffic leads to the poorest overall flow, while not considering the crash probability. Partial order in a lane-free system is similar to partial disorder in a lane-disciplined system in that both lead to decreased traffic capacity. This could explain the reason why standard enforcement methods, which rely on continuous increase of order, often fail to incur order to lane-free traffic systems. The results also provide an insight into the cooperative phenomena in open systems with self-driven particles.

Traffic State Estimation Using Connected Vehicles and Stationary Detectors

Directory of Open Access Journals (Sweden)

Ellen F. Grumert

2018-01-01

Full Text Available Real-time traffic state estimation is of importance for efficient traffic management. This is especially the case for traffic management systems that require fast detection of changes in the traffic conditions in order to apply an effective control measure. In this paper, we propose a method for estimating the traffic state and speed and density, by using connected vehicles combined with stationary detectors. The aim is to allow fast and accurate estimation of changes in the traffic conditions. The proposed method does only require information about the speed and the position of connected vehicles and can make use of sparsely located stationary detectors to limit the dependence on the infrastructure equipment. An evaluation of the proposed method is carried out by microscopic traffic simulation. The traffic state estimated using the proposed method is compared to the true simulated traffic state. Further, the density estimates are compared to density estimates from one detector-based method, one combined method, and one connected-vehicle-based method. The results of the study show that the proposed method is a promising alternative for estimating the traffic state in traffic management applications.

Traffic and Granular Flow ’03

CERN Document Server

Luding, Stefan; Bovy, Piet; Schreckenberg, Michael; Wolf, Dietrich

2005-01-01

These proceedings are the fifth in the series Traffic and Granular Flow, and we hope they will be as useful a reference as their predecessors. Both the realistic modelling of granular media and traffic flow present important challenges at the borderline between physics and engineering, and enormous progress has been made since 1995, when this series started. Still the research on these topics is thriving, so that this book again contains many new results. Some highlights addressed at this conference were the influence of long range electric and magnetic forces and ambient fluids on granular media, new precise traffic measurements, and experiments on the complex decision making of drivers. No doubt the “hot topics” addressed in granular matter research have diverged from those in traffic since the days when the obvious analogies between traffic jams on highways and dissipative clustering in granular flow intrigued both c- munities alike. However, now just this diversity became a stimulating feature of the ...

Study of air traffic over KLFIR

Science.gov (United States)

Nusyirwan, I. F.; Rohani, J. Mohd

2017-12-01

This paper shares the overview of the work currently being conducted with the Department of Civil Aviation Malaysia related to the air traffic. The aim is to study air traffic performance over KL and KK FIR, and the area of interest in this paper is the Kuala Lumpur Flight Information Region (KLFIR). The air traffic performance parameters includes general air traffic movement such as level allocation, number of movements, sector load analysis and also more specific parameters such as airborne delays, effects of weather to the air movements as well as ground delays. To achieve this, a huge effort has been undertaken that includes live data collection algorithm development and real time statistical analysis algorithm development. The main outcome from this multi-disciplinary work is the long-term analysis on the air traffic performance in Malaysia, which will put the country at par in the aviation community, namely the International Civil Aviation Organization (ICAO).

Road traffic noise and children's inattention.

Science.gov (United States)

Weyde, Kjell Vegard; Krog, Norun Hjertager; Oftedal, Bente; Magnus, Per; Øverland, Simon; Stansfeld, Stephen; Nieuwenhuijsen, Mark J; Vrijheid, Martine; de Castro Pascual, Montserrat; Aasvang, Gunn Marit

2017-11-21

An increasing number of children are exposed to road traffic noise levels that may lead to adverse effects on health and daily functioning. Childhood is a period of intense growth and brain maturation, and children may therefore be especially vulnerable to road traffic noise. The objective of the present study was to examine whether road traffic noise was associated with reported inattention symptoms in children, and whether this association was mediated by sleep duration. This study was based on the Norwegian Mother and Child Cohort Study conducted by the Norwegian Institute of Public Health. Parental reports of children's inattention at age 8 were linked to modelled levels of residential road traffic noise. We investigated the association between inattention and noise exposure during pregnancy (n = 1934), noise exposure averaged over 5 years (age 3 to 8 years; n = 1384) and noise exposure at age 8 years (n = 1384), using fractional logit response models. The participants were children from Oslo, Norway. An association with inattention at age 8 years was found for road traffic noise exposure at age 8 years (coef = .0083, CI = [.0012, .0154]; 1.2% point increase in inattention score per 10 dB increase in noise level), road traffic noise exposure average for the last 5 years (coef = .0090, CI = [.0016, .0164]; 1.3% point increase/10 dB), and for pregnancy road traffic noise exposure for boys (coef = .0091, CI = [.0010, .0171]), but not girls (coef = -.0021, CI = [-.0094, .0053]). Criteria for doing mediation analyses were not fulfilled. Results indicate that road traffic noise has a negative impact on children's inattention. We found no mediation by sleep duration.

Traffic Light Detection

DEFF Research Database (Denmark)

Philipsen, Mark Philip; Jensen, Morten Bornø; Møgelmose, Andreas

2015-01-01

Traffic light recognition (TLR) is an integral part of any intelligent vehicle, which must function in the existing infrastructure. Pedestrian and sign detection have recently seen great improvements due to the introduction of learning based detectors using integral channel features. A similar push...... database is collected based on footage from US roads. The database consists of both test and training data, totaling 46,418 frames and 112,971 annotated traffic lights, captured in continuous sequences under a varying light and weather conditions. The learning based detector achieves an AUC of 0.4 and 0...

32 CFR 636.12 - Traffic accident investigation.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Traffic accident investigation. 636.12 Section... ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.12 Traffic accident investigation. In addition to the requirements in § 634.28 of...

Android-based E-Traffic law enforcement system in Surakarta City

Science.gov (United States)

Yulianto, Budi; Setiono

2018-03-01

The urban advancement is always overpowered by the increasing number of vehicles as the need for movement of people and goods. This can lead to traffic problems if there is no effort on the implementation of traffic management and engineering, and traffic law enforcement. In this case, the Government of Surakarta City has implemented various policies and regulations related to traffic management and engineering in order to run traffic in an orderly, safe and comfortable manner according to the applicable law. However, conditions in the field shows that traffic violations still occurred frequently due to the weakness of traffic law enforcement in terms of human resources and the system. In this connection, a tool is needed to support traffic law enforcement, especially in relation to the reporting system of traffic violations. This study aims to develop an Android-based traffic violations reporting application (E-Traffic Law Enforcement) as part of the traffic law enforcement system in Surakarta City. The Android-apps records the location and time of the traffic violations incident along with the visual evidence of the infringement. This information will be connected to the database system to detect offenders and to do the traffic law enforcement process.

Reports on internet traffic statistics

NARCIS (Netherlands)

Hoogesteger, Martijn; de Oliveira Schmidt, R.; Sperotto, Anna; Pras, Aiko

2013-01-01

Internet traffic statistics can provide valuable information to network analysts and researchers about the way nowadays networks are used. In the past, such information was provided by Internet2 in a public website called Internet2 NetFlow: Weekly Reports. The website reported traffic statistics

Adaptive traffic control systems for urban networks

Directory of Open Access Journals (Sweden)

Radivojević Danilo

2017-01-01

Full Text Available Adaptive traffic control systems represent complex, but powerful tool for improvement of traffic flow conditions in locations or zones where applied. Many traffic agencies, especially those that have a large number of signalized intersections with high variability of the traffic demand, choose to apply some of the adaptive traffic control systems. However, those systems are manufactured and offered by multiple vendors (companies that are competing for the market share. Due to that fact, besides the information available from the vendors themselves, or the information from different studies conducted on different continents, very limited amount of information is available about the details how those systems are operating. The reason for that is the protecting of the intellectual property from plagiarism. The primary goal of this paper is to make a brief analysis of the functionalities, characteristics, abilities and results of the most recognized, but also less known adaptive traffic control systems to the professional public and other persons with interest in this subject.

OPTIMASI BANDWITH MENGGUNAKAN TRAFFIC SHAPPING

Directory of Open Access Journals (Sweden)

Imam Riadi

2012-05-01

Full Text Available Perkembangan layanan komunikasi telah berkembang sangat pesat. Salah satunya adalah pemanfaatan penggunaan bandwith untuk mengakases jaringan Internet. Traffic shapping bandwidth dapat memberikan efesiensi dalam hal pemanfaatan bandwidth pada instansi yang melakukan manajemen dalam lalulintas jaringannya. Metode yang digunakan dalam penelitian ini adalah metode literatur yaitu metode pengumpulan data yang dilakukan dengan mengumpulkan sumber-sumber data yang terkait dan metode eksperimen yaitu melakukan penelitian dengan mengkonfigurasi Mikrotik RouterOS untuk melakukan traffic shapping bandwidth. Hasil penelitian ini adalah router yang dapat melakukan traffic shapping sehingga kualitas koneksi menjadi lebih baik untuk mengakses dan mengambil data dari sebuah website.

Traffic Light Detection at Night

DEFF Research Database (Denmark)

Jensen, Morten Bornø; Philipsen, Mark Philip; Bahnsen, Chris

2015-01-01

Traffic light recognition (TLR) is an integral part of any in- telligent vehicle, it must function both at day and at night. However, the majority of TLR research is focused on day-time scenarios. In this paper we will focus on detection of traffic lights at night and evalu- ate the performance...... of three detectors based on heuristic models and one learning-based detector. Evaluation is done on night-time data from the public LISA Traffic Light Dataset. The learning-based detector out- performs the model-based detectors in both precision and recall. The learning-based detector achieves an average...

Analysis of factors temporarily impacting traffic sign readability

Directory of Open Access Journals (Sweden)

Majid Khalilikhah

2016-10-01

Full Text Available Traffic sign readability can be affected by the existence of dirt on traffic sign faces. However, among damaged signs, dirty traffic signs are unique since their damage is not permanent and they just can be cleaned instead of replaced. This study aimed to identify the most important factors contributing to traffic sign dirt. To do so, a large number of traffic signs in Utah were measured by deploying a vehicle instrumented with mobile LiDAR imaging and digital photolog technologies. Each individual daytime digital image was inspected for dirt. Location and climate observations obtained from official sources were compiled using ArcGIS throughout the process. To identify contributing factors to traffic sign dirt, the chi-square test was employed. To analyze the data and rank all of the factors based on their importance to the sign dirt, Random forests statistical model was utilized. After analyzing the data, it can be concluded that ground elevation, sign mount height, and air pollution had the highest effect on making traffic signs dirty. The findings of this investigation assist transportation agencies in determining traffic signs with a higher likelihood of sign dirt. In this way, agencies would schedule to clean such traffic signs more frequently.

Traffic Flow Wide-Area Surveillance system

Energy Technology Data Exchange (ETDEWEB)

Allgood, G.O.; Ferrell, R.K.; Kercel, S.W.; Abston, R.A.

1994-09-01

Traffic management can be thought of as a stochastic queuing process where the serving time at one of its control points is dynamically linked to the global traffic pattern, which is, in turn, dynamically linked to the control point. For this closed-loop system to be effective, the traffic management system must sense and interpret a large spatial projection of data originating from multiple sensor suites. This concept is the basis for the development of a Traffic Flow Wide-Area Surveillance (TFWAS) system. This paper presents the results of a study by Oak Ridge National Laboratory to define the operational specifications and characteristics, to determine the constraints, and to examine the state of technology of a TFWAS system in terms of traffic management and control. In doing so, the functions and attributes of a TFWAS system are mapped into an operational structure consistent with the Intelligent Vehicle Highway System (IVHS) concept and the existing highway infrastructure. This mapping includes identifying candidate sensor suites and establishing criteria, requirements, and performance measures by which these systems can be graded in their ability and practicality to meet the operational requirements of a TFWAS system. In light of this, issues such as system integration, applicable technologies, impact on traffic management and control, and public acceptance are addressed.

Traffic flow wide-area surveillance system

Science.gov (United States)

Allgood, Glenn O.; Ferrell, Regina K.; Kercel, Stephen W.; Abston, Ruth A.

1995-01-01

Traffic management can be thought of as a stochastic queuing process where the serving time at one of its control points is dynamically linked to the global traffic pattern, which is, in turn, dynamically linked to the control point. For this closed-loop system to be effective, the traffic management system must sense and interpret a large spatial projection of data originating from multiple sensor suites. This concept is the basis for the development of a traffic flow wide-area surveillance (TFWAS) system. This paper presents the results of a study by Oak Ridge National Laboratory to define the operational specifications and characteristics, to determine the constraints, and to examine the state of technology of a TFWAS system in terms of traffic management and control. In doing so, the functions and attributes of a TFWAS system are mapped into an operational structure consistent with the Intelligent Vehicle Highway System (IVHS) concept and the existing highway infrastructure. This mapping includes identifying candidate sensor suites and establishing criteria, requirements, and performance measures by which these systems can be graded in their ability and practicality to meet the operational requirements of a TFWAS system. In light of this, issues such as system integration, applicable technologies, impact on traffic management and control, and public acceptance are addressed.

Minimal-delay traffic grooming for WDM star networks

Science.gov (United States)

Choi, Hongsik; Garg, Nikhil; Choi, Hyeong-Ah

2003-10-01

All-optical networks face the challenge of reducing slower opto-electronic conversions by managing assignment of traffic streams to wavelengths in an intelligent manner, while at the same time utilizing bandwidth resources to the maximum. This challenge becomes harder in networks closer to the end users that have insufficient data to saturate single wavelengths as well as traffic streams outnumbering the usable wavelengths, resulting in traffic grooming which requires costly traffic analysis at access nodes. We study the problem of traffic grooming that reduces the need to analyze traffic, for a class of network architecture most used by Metropolitan Area Networks; the star network. The problem being NP-complete, we provide an efficient twice-optimal-bound greedy heuristic for the same, that can be used to intelligently groom traffic at the LANs to reduce latency at the access nodes. Simulation results show that our greedy heuristic achieves a near-optimal solution.

Traffic experiment reveals the nature of car-following.

Science.gov (United States)

Jiang, Rui; Hu, Mao-Bin; Zhang, H M; Gao, Zi-You; Jia, Bin; Wu, Qing-Song; Wang, Bing; Yang, Ming

2014-01-01

As a typical self-driven many-particle system far from equilibrium, traffic flow exhibits diverse fascinating non-equilibrium phenomena, most of which are closely related to traffic flow stability and specifically the growth/dissipation pattern of disturbances. However, the traffic theories have been controversial due to a lack of precise traffic data. We have studied traffic flow from a new perspective by carrying out large-scale car-following experiment on an open road section, which overcomes the intrinsic deficiency of empirical observations. The experiment has shown clearly the nature of car-following, which runs against the traditional traffic flow theory. Simulations show that by removing the fundamental notion in the traditional car-following models and allowing the traffic state to span a two-dimensional region in velocity-spacing plane, the growth pattern of disturbances has changed qualitatively and becomes qualitatively or even quantitatively in consistent with that observed in the experiment.

Network Analysis of Urban Traffic with Big Bus Data

OpenAIRE

Zhao, Kai

2016-01-01

Urban traffic analysis is crucial for traffic forecasting systems, urban planning and, more recently, various mobile and network applications. In this paper, we analyse urban traffic with network and statistical methods. Our analysis is based on one big bus dataset containing 45 million bus arrival samples in Helsinki. We mainly address following questions: 1. How can we identify the areas that cause most of the traffic in the city? 2. Why there is a urban traffic? Is bus traffic a key cause ...

Physics of traffic gridlock in a city.

Science.gov (United States)

Kerner, Boris S

2011-10-01

Based on simulations of stochastic three-phase and two-phase traffic flow models, we reveal that at a signalized city intersection under small link inflow rates at which a vehicle queue developed during the red phase of the light signal dissolves fully during the green phase, i.e., no traffic gridlock should be expected, nevertheless, spontaneous traffic breakdown with subsequent city gridlock occurs with some probability after a random time delay. In most cases, this traffic breakdown is initiated by a phase transition from free flow to a synchronized flow occurring upstream of the queue at the light signal. The probability of traffic breakdown at the light signal is an increasing function of the link inflow rate and duration of the red phase of the light signal.

Testing block subdivision algorithms on block designs

Science.gov (United States)

Wiseman, Natalie; Patterson, Zachary

2016-01-01

Integrated land use-transportation models predict future transportation demand taking into account how households and firms arrange themselves partly as a function of the transportation system. Recent integrated models require parcels as inputs and produce household and employment predictions at the parcel scale. Block subdivision algorithms automatically generate parcel patterns within blocks. Evaluating block subdivision algorithms is done by way of generating parcels and comparing them to those in a parcel database. Three block subdivision algorithms are evaluated on how closely they reproduce parcels of different block types found in a parcel database from Montreal, Canada. While the authors who developed each of the algorithms have evaluated them, they have used their own metrics and block types to evaluate their own algorithms. This makes it difficult to compare their strengths and weaknesses. The contribution of this paper is in resolving this difficulty with the aim of finding a better algorithm suited to subdividing each block type. The proposed hypothesis is that given the different approaches that block subdivision algorithms take, it's likely that different algorithms are better adapted to subdividing different block types. To test this, a standardized block type classification is used that consists of mutually exclusive and comprehensive categories. A statistical method is used for finding a better algorithm and the probability it will perform well for a given block type. Results suggest the oriented bounding box algorithm performs better for warped non-uniform sites, as well as gridiron and fragmented uniform sites. It also produces more similar parcel areas and widths. The Generalized Parcel Divider 1 algorithm performs better for gridiron non-uniform sites. The Straight Skeleton algorithm performs better for loop and lollipop networks as well as fragmented non-uniform and warped uniform sites. It also produces more similar parcel shapes and patterns.

Development of a mobile application for manual traffic counts

Directory of Open Access Journals (Sweden)

Ghanim Mohammad

2017-01-01

Full Text Available The use of technology in performing traffic counts has become widely used by many transportation agencies and private sectors. Different technologies have been employed to perform such counts, such as inductive loops, image processing, Bluetooth technologies, and laser and infrared technologies. However, the use of these advanced technologies come with extra cost to develop, install, and maintain. While the use of advanced technologies provide reliable traffic counts and vehicle classifications data, the use of manual traffic is an inevitable task. Manual traffic counts can serve different purposes, such as performing quality control or conducting short-term traffic survey. Manual traffic counts are usually conducted with the use of the traditional paper-and-pencil approach or the use of hand-held devices that are specifically developed to assess performing manual traffic counts. In this paper, the development of a mobile app that can be used to assist those who need to perform manual traffic counts. The app can be used by many public agencies, private sectors, and college students to collect their traffic data. It also provides users with the capabilities of sharing their traffic counts instantly, where traffic counts can be extracted and processed quickly by other parties.

Development of Road Traffic Assignment and Assessment Sub-Model Applied in the Traffic Study ...

Directory of Open Access Journals (Sweden)

Dražen Topolnik

2012-10-01

Full Text Available The described sub-model is just one small segment of theTraffic Study of the City of Zagreb, in the development of whichnumerous foreign and national experts and institutions tookpart. After comprehensive collection and processing of inputdata, the traffic experts, using the software package "MVATRIPS" for the analysis and search for optimal solutions to theproblem of traffic system, provided the models of public urbantransit for the future.This paper describes the analysis and assessment of sub-models in road traffic assignment for the morning peak, afternoonpeak and average off-peak hours. The principles of assignmentprocedure have been described as well as the convergencetests. The following has been specified: the users categories,the public transit pre-load, and the passenger car unit(PC U. The key guideline in selecting the route is a generalisedformulation of costs presented in the paper. The procedures ofcalibration and the assessment of the finite model have alsobeen defined according to the screenline flows, link flows, andtravelling times. In the end, the summary is given of the basiccharacteristics of the finite travelling matrices.

Seat belt, DWI, and other traffic violations among recent immigrants in Florida and Tennessee : traffic tech.

Science.gov (United States)

2013-05-01

The rapidly changing racial and ethnic composition of the : U.S. population is important to traffic safety specialists : because involvement in fatal traffic crashes varies across : racial and ethnic groups. Some research suggests that certain : mino...

A Brief Introduction of Air Traffic Management

Institute of Scientific and Technical Information of China (English)

1997-01-01

Air Traffic Management (ATM) started publication in 1995 by Air Traffic Management Bureau of CAAC. It is the first magazine about ATM field in CAAC. The chairman of Editorial Board of ATM is Mr. Bao Peide, Vice Minister of CAAC. Mr. Chen Ziye, Vice President of the 1st Research Institute of CAAC and Chen Xuhua, General Director of Air Traffic Management Bureau are vice chairmen of the editorial board, and six general directors of local air traffic management bureau and some professors and experts are members of the editorial board.

Air Traffic Management Research at NASA Ames

Science.gov (United States)

Davis, Thomas J.

2012-01-01

The Aviation Systems Division at the NASA Ames Research Center conducts leading edge research in air traffic management concepts and technologies. This overview will present concepts and simulation results for research in traffic flow management, safe and efficient airport surface operations, super density terminal area operations, separation assurance and system wide modeling and simulation. A brief review of the ongoing air traffic management technology demonstration (ATD-1) will also be presented. A panel discussion, with Mr. Davis serving as a panelist, on air traffic research will follow the briefing.

Phase Plane Analysis Method of Nonlinear Traffic Phenomena

Directory of Open Access Journals (Sweden)

Wenhuan Ai

2015-01-01

Full Text Available A new phase plane analysis method for analyzing the complex nonlinear traffic phenomena is presented in this paper. This method makes use of variable substitution to transform a traditional traffic flow model into a new model which is suitable for the analysis in phase plane. According to the new model, various traffic phenomena, such as the well-known shock waves, rarefaction waves, and stop-and-go waves, are analyzed in the phase plane. From the phase plane diagrams, we can see the relationship between traffic jams and system instability. So the problem of traffic flow could be converted into that of system stability. The results show that the traffic phenomena described by the new method is consistent with that described by traditional methods. Moreover, the phase plane analysis highlights the unstable traffic phenomena we are chiefly concerned about and describes the variation of density or velocity with time or sections more clearly.

Green Wave Traffic Optimization - A Survey

DEFF Research Database (Denmark)

Warberg, Andreas; Larsen, Jesper; Jørgensen, Rene Munk

The objective of this survey is to cover the research in the area of adaptive traffic control with emphasis on the applied optimization methods. The problem of optimizing traffic signals can be viewed in various ways, depending on political, economic and ecological goals. The survey highlights some...... important conflicts, which support the notion that traffic signal optimization is a multi-objective problem, and relates this to the most common measures of effectiveness. A distinction can be made between classical systems, which operate with a common cycle time, and the more flexible, phase......-based, approach, which is shown to be more suitable for adaptive traffic control. To support this claim three adaptive systems, which use alternatives to the classical optimization procedures, are described in detail....

Abstract Description of Internet Traffic of Generalized Cauchy Type

Directory of Open Access Journals (Sweden)

Ming Li

2012-01-01

. Therefore, there is a limitation for fGn to accurately model traffic. Recently, the generalized Cauchy (GC process was introduced to model traffic with the flexibility to separately measure the fractal dimension DGC and the Hurst parameter HGC of traffic. However, there is a fundamental problem whether or not there exists the generality that the GC model is more conformable with real traffic than single parameter models, such as fGn, irrelevant of traffic traces used in experimental verification. The solution to that problem remains unknown but is desired for model evaluation in traffic theory or for model selection against specific issues, such as queuing analysis relating to the autocorrelation function (ACF of arrival traffic. The key contribution of this paper is our solution to that fundamental problem (see Theorem 3.17 with the following features in analysis. (i Set-valued analysis of the traffic of the fGn type. (ii Set-valued analysis of the traffic of the GC type. (iii Revealing the generality previously mentioned by comparing metrics of the traffic of the fGn type to that of the GC type.

Detecting Anomaly in Traffic Flow from Road Similarity Analysis

KAUST Repository

Liu, Xinran

2016-06-02

Taxies equipped with GPS devices are considered as 24-hour moving sensors widely distributed in urban road networks. Plenty of accurate and realtime trajectories of taxi are recorded by GPS devices and are commonly studied for understanding traffic dynamics. This paper focuses on anomaly detection in traffic volume, especially the non-recurrent traffic anomaly caused by unexpected or transient incidents, such as traffic accidents, celebrations and disasters. It is important to detect such sharp changes of traffic status for sensing abnormal events and planning their impact on the smooth volume of traffic. Unlike existing anomaly detection approaches that mainly monitor the derivation of current traffic status from history in the past, the proposed method in this paper evaluates the abnormal score of traffic on one road by comparing its current traffic volume with not only its historical data but also its neighbors. We define the neighbors as the roads that are close in sense of both geo-location and traffic patterns, which are extracted by matrix factorization. The evaluation results on trajectories data of 12,286 taxies over four weeks in Beijing show that our approach outperforms other baseline methods with higher precision and recall.

A Wavelet Analysis-Based Dynamic Prediction Algorithm to Network Traffic

Directory of Open Access Journals (Sweden)

Meng Fan-Bo

2016-01-01

Full Text Available Network traffic is a significantly important parameter for network traffic engineering, while it holds highly dynamic nature in the network. Accordingly, it is difficult and impossible to directly predict traffic amount of end-to-end flows. This paper proposes a new prediction algorithm to network traffic using the wavelet analysis. Firstly, network traffic is converted into the time-frequency domain to capture time-frequency feature of network traffic. Secondly, in different frequency components, we model network traffic in the time-frequency domain. Finally, we build the prediction model about network traffic. At the same time, the corresponding prediction algorithm is presented to attain network traffic prediction. Simulation results indicates that our approach is promising.

Criminal Liability for Serious Traffic Offences : Essays on Causing Death, Injury and Danger in Traffic

NARCIS (Netherlands)

van Dijk, Alwin; Wolswijk, Hein

2015-01-01

The criminal law on serious traffic offences is a fascinating area. The traffic context presents legislators with numerous controversial issues. One such issue is when severe consequences are matched with low moral culpability. How should the law deal with a driver who kills someone because she

Accurate Multisteps Traffic Flow Prediction Based on SVM

Directory of Open Access Journals (Sweden)

Zhang Mingheng

2013-01-01

Full Text Available Accurate traffic flow prediction is prerequisite and important for realizing intelligent traffic control and guidance, and it is also the objective requirement for intelligent traffic management. Due to the strong nonlinear, stochastic, time-varying characteristics of urban transport system, artificial intelligence methods such as support vector machine (SVM are now receiving more and more attentions in this research field. Compared with the traditional single-step prediction method, the multisteps prediction has the ability that can predict the traffic state trends over a certain period in the future. From the perspective of dynamic decision, it is far important than the current traffic condition obtained. Thus, in this paper, an accurate multi-steps traffic flow prediction model based on SVM was proposed. In which, the input vectors were comprised of actual traffic volume and four different types of input vectors were compared to verify their prediction performance with each other. Finally, the model was verified with actual data in the empirical analysis phase and the test results showed that the proposed SVM model had a good ability for traffic flow prediction and the SVM-HPT model outperformed the other three models for prediction.

Life-Times of Simulated Traffic Jams

OpenAIRE

Nagel, K.

1993-01-01

We study a model for freeway traffic which includes strong noise taking into account the fluctuations of individual driving behavior. The model shows emergent traffic jams with a self-similar appearance near the throughput maximum of the traffic. The lifetime distribution of these jams shows a short scaling regime, which gets considerably longer if one reduces the fluctuations for driving at maximum speed but leaves the fluctuations for slowing down or accelerating unchanged. The outflow from...

A theory of traffic congestion at moving bottlenecks

Energy Technology Data Exchange (ETDEWEB)

Kerner, Boris S [Daimler AG, GR/PTF, HPC: G021, 71059 Sindelfingen (Germany); Klenov, Sergey L, E-mail: boris.kerner@daimler.co [Department of Physics, Moscow Institute of Physics and Technology, 141700 Dolgoprudny, Moscow Region (Russian Federation)

2010-10-22

The physics of traffic congestion occurring at a moving bottleneck on a multi-lane road is revealed based on the numerical analyses of vehicular traffic with a discrete stochastic traffic flow model in the framework of three-phase traffic theory. We find that there is a critical speed of a moving bottleneck at which traffic breakdown, i.e. a first-order phase transition from free flow to synchronized flow, occurs spontaneously at the moving bottleneck, if the flow rate upstream of the bottleneck is great enough. The greater the flow rate, the higher the critical speed of the moving bottleneck. A diagram of congested traffic patterns at the moving bottleneck is found, which shows regions in the flow-rate-moving-bottleneck-speed plane in which congested patterns emerge spontaneously or can be induced through large enough disturbances in an initial free flow. A comparison of features of traffic breakdown and resulting congested patterns at the moving bottleneck with known ones at an on-ramp (and other motionless) bottleneck is made. Nonlinear features of complex interactions and transformations of congested traffic patterns occurring at on- and off-ramp bottlenecks due to the existence of the moving bottleneck are found. The physics of the phenomenon of traffic congestion due to 'elephant racing' on a multi-lane road is revealed.

A theory of traffic congestion at moving bottlenecks

International Nuclear Information System (INIS)

Kerner, Boris S; Klenov, Sergey L

2010-01-01

The physics of traffic congestion occurring at a moving bottleneck on a multi-lane road is revealed based on the numerical analyses of vehicular traffic with a discrete stochastic traffic flow model in the framework of three-phase traffic theory. We find that there is a critical speed of a moving bottleneck at which traffic breakdown, i.e. a first-order phase transition from free flow to synchronized flow, occurs spontaneously at the moving bottleneck, if the flow rate upstream of the bottleneck is great enough. The greater the flow rate, the higher the critical speed of the moving bottleneck. A diagram of congested traffic patterns at the moving bottleneck is found, which shows regions in the flow-rate-moving-bottleneck-speed plane in which congested patterns emerge spontaneously or can be induced through large enough disturbances in an initial free flow. A comparison of features of traffic breakdown and resulting congested patterns at the moving bottleneck with known ones at an on-ramp (and other motionless) bottleneck is made. Nonlinear features of complex interactions and transformations of congested traffic patterns occurring at on- and off-ramp bottlenecks due to the existence of the moving bottleneck are found. The physics of the phenomenon of traffic congestion due to 'elephant racing' on a multi-lane road is revealed.

Modelling of H.264 MPEG2 TS Traffic Source

Directory of Open Access Journals (Sweden)

Stanislav Klucik

2013-01-01

Full Text Available This paper deals with IPTV traffic source modelling. Traffic sources are used for simulation, emulation and real network testing. This model is made as a derivation of known recorded traffic sources that are analysed and statistically processed. As the results show the proposed model causes in comparison to the known traffic source very similar network traffic parameters when used in a simulated network.

UTRaLab – Urban Traffic Research Laboratory

Directory of Open Access Journals (Sweden)

Karsten Kozempel

2017-08-01

Full Text Available The Urban Traffic Research Laboratory (UTRaLab is a research and test track for traffic detection methods and sensors. It is located at the Ernst-Ruska-Ufer, in the southeast of the city of Berlin (Germany. The UTRaLab covers 1 km of a highly-frequented urban road and is connected to a motorway. It is equipped with two gantries with distance of 850 m in between and has several outstations for data collection. The gantries contain many different traffic sensors like inductive loops, cameras, lasers or wireless sensors for traffic data acquisition. Additionally a weather station records environmental data. The UTRaLab’s main purposes are the data collection of traffic data on the one hand and testing newly developed sensors on the other hand.

Decline traffic information system

Energy Technology Data Exchange (ETDEWEB)

Du Plessis, K [Computer Sciences Corporation (CSC), Sydney (Australia)

2007-09-06

BHP Billion (BHPB) Cannington has experienced problems in regards to their traffic flow in the decline at the mine. The problems related to reports on near misses of vehicles moving towards each other in the decline. The decline is also to narrow for trucks to pass each other and the operators need to be aware of oncoming traffic in the decline to ensure they could take early evasive steps to ensure the rules of right of way in the decline are adhered to. BHPB Cannington requested CSC to conduct a problem analysis and to provide a solutions proposal to Cannington. The solution was put forward as an augmentation of their current safety procedures used with in the decline. During this phase of the project CSC developed a solutions architecture which involved the use of Active (Radio Frequency Identification) RFID tagging which will enable vehicle movement tracking on a real time basis after which the appropriate traffic movement can be relayed to the operators in the decline. The primary objective of the DTIS is to provide accurate information of traffic movement in the decline and present that information to the operators of the decline IN THE DECLINE upon which they would make their decisions. (orig.)

Traffic improvement and transportation pollution control in Xiamen

Energy Technology Data Exchange (ETDEWEB)

Dongxing Yuan; Zilin, Wu

1996-12-31

in this paper, the urban traffic improvement and transportation control in Xiamen are highlighted. Xiamen is a port city and an economical special zone of China. As the economy grows, the transportation is developing dramatically and becoming the key for further economic development. The air quality is threatened by the rapid growth of the vehicles in the city. The most urgent task in improving urban traffic is to establish a sound traffic system. The municipal government takes great effort to improve the traffic condition, as well as to reduce green house gases and protect air environment. Some management and technical measures are carried out. Those management measures are mainly as follows: (1) systematic planning of the city arrangement and city functional division, and integrated planning of the urban roads system, (2) putting great emphasis on tail gas monitoring and management, and (3) establishing optimized utilization of motor vehicles. Those included in the main technical measures are (1) making the roads clear, (2) enlarging traffic capacity, and (3) developing the public transport. The most urgent task in improving urban traffic is to establish a sound traffic system. The city municipal government and Transportation Management Bureau plan to make a series of reforms to improve the urban traffic condition, such as building high quality road around the city, reducing the number of one way roads and replacing gasoline buses with electric buses. An optimized traffic system of Xiamen, taking public transport as the main means, is the key to meet the needs of both traffic improvement and urban transportation pollution control.

Virtual Reality Game Education to Learn Traffic Regulation

Directory of Open Access Journals (Sweden)

Andru Deva Lukito

2017-10-01

Full Text Available Abstract – Traffic accident has become number 3 of children death cause in the world according to WHO[1]. Traffic accident that involve children often caused by their own by breaking the law or regulation. Therefor education about traffic regulation and law including traffic sign and its meaning must be given to children early. Because education means process to change a person or a group attitude and behavior in order to make them mature through teaching and training [2]. One of them that can be used is digital media.  One of interactive digital media is digital game, various form of digital game start from 2D, 2.5D, 3D with many point of view and new technology. VR (Virtual Reality as new digital media where alternate reality exist to test various theory without any real consequences, according to Greenbaum “Virtual Reality is an alternate world filled with computer-generated images that respond to human movements. These simulated environments are usually visited with the aid of an expensive data suit which features stereophonic video goggles and fiber-optic data gloves”[3]. Greenbaum statement before were make VR suitable to test traffic law and regulation and educate kid to obey the traffic sign and regulation without real consequences from real world. This Journal contain the result of using virtual reality as traffic regulation education media. Education material that arranged consisting traffic sign that appear on the road and safety riding gear. Keywords – Virtual Reality, Traffic sign, Road traffic, children, education

Increase the Safety of Road Traffic Accidents by Applying Clustering

Directory of Open Access Journals (Sweden)

Kos Goran

2013-12-01

Full Text Available In terms of continual increase of number of traffic accidents and alarming trend of increasing number of traffic accidents with catastrophic consequences for human life and health, it is necessary to actively research and develop methods to combat these trends. One of the measures is the implementation of advanced information systems in existing traffic environment. Accidents clusters, as databases of traffic accidents, introduce a new dimension in traffic systems in the form of experience, providing information on current accidents and the ones that have previously occurred in a given period. This paper proposes a new approach to predictive management of traffic processes, based on the collection of data in real time and is based on accidents clusters. The modern traffic information services collects road traffic status data from a wide variety of traffic sensing systems using modern ICT technologies, creating the most accurate road traffic situation awareness achieved so far. Road traffic situation awareness enhanced by accident clusters' data can be visualized and distributed in various ways (including the forms of dynamic heat maps and on various information platforms, suiting the requirements of the end-users. Accent is placed on their significant features that are based on additional knowledge about existing traffic processes and distribution of important traffic information in order to prevent and reduce traffic accidents.

Congestion and communication in confined ant traffic

Science.gov (United States)

Gravish, Nick; Gold, Gregory; Zangwill, Andrew; Goodisman, Michael A. D.; Goldman, Daniel I.

2014-03-01

Many social animals move and communicate within confined spaces. In subterranean fire ants Solenopsis invicta, mobility within crowded nest tunnels is important for resource and information transport. Within confined tunnels, communication and traffic flow are at odds: trafficking ants communicate through tactile interactions while stopped, yet ants that stop to communicate impose physical obstacles on the traffic. We monitor the bi-directional flow of fire ant workers in laboratory tunnels of varied diameter D. The persistence time of communicating ant aggregations, τ, increases approximately linearly with the number of participating ants, n. The sensitivity of traffic flow increases as D decreases and diverges at a minimum diameter, Dc. A cellular automata model incorporating minimal traffic features--excluded volume and communication duration--reproduces features of the experiment. From the model we identify a competition between information transfer and the need to maintain jam-free traffic flow. We show that by balancing information transfer and traffic flow demands, an optimum group strategy exists which maximizes information throughput. We acknowledge funding from NSF PoLS #0957659 and #PHY-1205878.

Bound Maxima as a Traffic Feature under DDOS Flood Attacks

Directory of Open Access Journals (Sweden)

Jie Xue

2012-01-01

Full Text Available This paper gives a novel traffic feature for identifying abnormal variation of traffic under DDOS flood attacks. It is the histogram of the maxima of the bounded traffic rate on an interval-by-interval basis. We use it to experiment on the traffic data provided by MIT Lincoln Laboratory under Defense Advanced Research Projects Agency (DARPA in 1999. The experimental results profitably enhance the evidences that traffic rate under DDOS attacks is statistically higher than that of normal traffic considerably. They show that the pattern of the histogram of the maxima of bounded rate of attack-contained traffic greatly differs from that of attack-free traffic. Besides, the present traffic feature is simple in mathematics and easy to use in practice.

Patients' Risk of Causing Traffic Violations and Traffic Accidents while Driving.

Science.gov (United States)

Šestan, Nevenka; Dodič Fikfak, Metoda; Balantič, Zvone

2017-09-01

This study examines whether drivers suffering from epilepsy, chronic alcoholism and/or hazardous drinking, psychoactive substance abuse, other diseases of the nervous system, mental and behavioural disorders, cardiovascular diseases, severe diabetes, and severe eye diseases are at a greater risk of causing traffic accidents and traffic violations than drivers that cause accidents and violations without these diagnoses. A case control study was carried out. The cases were drivers checked by a special medical committee in the period observed suffering from the diseases listed above. Matched controls were taken from the cohort of those that caused accidents and violations during the same period observed. The descriptive statistics were followed by calculation of correlations, t-tests and χ 2 , and the odds ratio. Drivers with referrals for diseases of the nervous system are five times more likely to cause a traffic accident compared to controls (OR=5.18; 95% CI=2.59-10.34); in addition, a high risk is associated with drivers with mental and behavioural disorders (OR=3.64; 95% CI=1.91-6.94), drivers with epilepsy (OR=1.99; 95% CI=1.01-3.92), and drivers addicted to alcohol (OR=1.71; 95% CI=1.01-2.89). Drivers suffering from addiction, a disease of the nervous system, or epilepsy are more likely to cause a traffic accident, which is a contribution to the inconclusive findings of previous studies. The multiple reasons for risks of patients suffering from mental and behavioural disorders need to be further investigated. Copyright© by the National Institute of Public Health, Prague 2017

Analysis of Child-related Road Traffic Accidents in Vietnam

Science.gov (United States)

Vu, Anh Tuan; Nguyen, Dinh Vinh Man

2018-04-01

In recent years, the number of road traffic accidents, fatalities and injuries have been decreasing, but the figures of children road traffic accidents have been increasing in Ho Chi Minh City of Vietnam. This fact strongly calls for implementing effective solutions to improve traffic safety for children by the local government. This paper presents the trends, patterns and causes of road traffic accidents involving children based on the analysis of road traffic accident data over the period 2010-2015 and the video-based observations of road traffic law violations at 15 typical school gates and 10 typical roads. The results could be useful for the city government to formulate solutions to effectively improve traffic safety for children in Ho Chi Minh City and other cities in Vietnam.

Differential endosomal sorting of a novel P2Y12 purinoreceptor mutant.

Science.gov (United States)

Cunningham, Margaret R; Nisar, Shaista P; Cooke, Alexandra E; Emery, Elizabeth D; Mundell, Stuart J

2013-05-01

P2Y12 receptor internalization and recycling play an essential role in ADP-induced platelet activation. Recently, we identified a patient with a mild bleeding disorder carrying a heterozygous mutation of P2Y12 (P341A) whose P2Y12 receptor recycling was significantly compromised. Using human cell line models, we identified key proteins regulating wild-type (WT) P2Y12 recycling and investigated P2Y12 -P341A receptor traffic. Treatment with ADP resulted in delayed Rab5-dependent internalization of P341A when compared with WT P2Y12 . While WT P2Y12 rapidly recycled back to the membrane via Rab4 and Rab11 recycling pathways, limited P341A recycling was observed, which relied upon Rab11 activity. Although minimal receptor degradation was evident, P341A was localized in Rab7-positive endosomes with considerable agonist-dependent accumulation in the trans-Golgi network (TGN). Rab7 activity is known to facilitate recruitment of retromer complex proteins to endosomes to transport cargo to the TGN. Here, we identified that P341A colocalized with Vps26; depletion of which blocked limited recycling and promoted receptor degradation. This study has identified key points of divergence in the endocytic traffic of P341A versus WT-P2Y12 . Given that these pathways are retained in human platelets, this research helps define the molecular mechanisms regulating P2Y12 receptor traffic and explain the compromised receptor function in the platelets of the P2Y12 -P341A-expressing patient. © 2013 John Wiley & Sons A/S.

Website Detection Using Remote Traffic Analysis

OpenAIRE

Gong, Xun; Kiyavash, Negar; Schear, Nabíl; Borisov, Nikita

2011-01-01

Recent work in traffic analysis has shown that traffic patterns leaked through side channels can be used to recover important semantic information. For instance, attackers can find out which website, or which page on a website, a user is accessing simply by monitoring the packet size distribution. We show that traffic analysis is even a greater threat to privacy than previously thought by introducing a new attack that can be carried out remotely. In particular, we show that, to perform traffi...

Nitrogen deposition and traffic. State-of-the-art

International Nuclear Information System (INIS)

Teeuwisse, S.

2010-01-01

Nitrogen deposition is caused, among other things, by road traffic. This article addresses the relation between traffic and nitrogen deposition and the manner in which the contribution of traffic to nitrogen deposition can be quantified. [nl

40 CFR 93.128 - Traffic signal synchronization projects.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Traffic signal synchronization... synchronization projects. Traffic signal synchronization projects may be approved, funded, and implemented without... include such regionally significant traffic signal synchronization projects. ...

A queuing model for road traffic simulation

International Nuclear Information System (INIS)

Guerrouahane, N.; Aissani, D.; Bouallouche-Medjkoune, L.; Farhi, N.

2015-01-01

We present in this article a stochastic queuing model for the raod traffic. The model is based on the M/G/c/c state dependent queuing model, and is inspired from the deterministic Godunov scheme for the road traffic simulation. We first propose a variant of M/G/c/c state dependent model that works with density-flow fundamental diagrams rather than density-speed relationships. We then extend this model in order to consider upstream traffic demand as well as downstream traffic supply. Finally, we show how to model a whole raod by concatenating raod sections as in the deterministic Godunov scheme

The impact of a congestion assistant on traffic flow efficiency and safety in congested traffic caused by a lane drop

NARCIS (Netherlands)

van Driel, Cornelie; van Arem, Bart

2010-01-01

This article presents the results of a microscopic traffic simulation study conducted to investigate the impact of a Congestion Assistant on traffic efficiency and traffic safety. The Congestion Assistant is an in-vehicle system in which an active pedal supports the driver when approaching

Cutaneous Sensory Block Area, Muscle-Relaxing Effect, and Block Duration of the Transversus Abdominis Plane Block

DEFF Research Database (Denmark)

Støving, Kion; Rothe, Christian; Rosenstock, Charlotte V

2015-01-01

BACKGROUND AND OBJECTIVES: The transversus abdominis plane (TAP) block is a widely used nerve block. However, basic block characteristics are poorly described. The purpose of this study was to assess the cutaneous sensory block area, muscle-relaxing effect, and block duration. METHODS: Sixteen...... healthy volunteers were randomized to receive an ultrasound-guided unilateral TAP block with 20 mL 7.5 mg/mL ropivacaine and placebo on the contralateral side. Measurements were performed at baseline and 90 minutes after performing the block. Cutaneous sensory block area was mapped and separated...... into a medial and lateral part by a vertical line through the anterior superior iliac spine. We measured muscle thickness of the 3 lateral abdominal muscle layers with ultrasound in the relaxed state and during maximal voluntary muscle contraction. The volunteers reported the duration of the sensory block...

Using Automated Planning for Traffic Signals Control

Directory of Open Access Journals (Sweden)

Matija Gulić

2016-08-01

Full Text Available Solving traffic congestions represents a high priority issue in many big cities. Traditional traffic control systems are mainly based on pre-programmed, reactive and local techniques. This paper presents an autonomic system that uses automated planning techniques instead. These techniques are easily configurable and modified, and can reason about the future implications of actions that change the default traffic lights behaviour. The proposed implemented system includes some autonomic properties, since it monitors the current traffic state, detects if the system is degrading its performance, sets up new sets of goals to be achieved by the planner, triggers the planner that generates plans with control actions, and executes the selected courses of actions. The obtained results in several artificial and real world data-based simulation scenarios show that the proposed system can efficiently solve traffic congestion.

Distributed traffic signal control using fuzzy logic

Science.gov (United States)

Chiu, Stephen

1992-01-01

We present a distributed approach to traffic signal control, where the signal timing parameters at a given intersection are adjusted as functions of the local traffic condition and of the signal timing parameters at adjacent intersections. Thus, the signal timing parameters evolve dynamically using only local information to improve traffic flow. This distributed approach provides for a fault-tolerant, highly responsive traffic management system. The signal timing at an intersection is defined by three parameters: cycle time, phase split, and offset. We use fuzzy decision rules to adjust these three parameters based only on local information. The amount of change in the timing parameters during each cycle is limited to a small fraction of the current parameters to ensure smooth transition. We show the effectiveness of this method through simulation of the traffic flow in a network of controlled intersections.

A Cooperative Traffic Control of Vehicle–Intersection (CTCVI) for the Reduction of Traffic Delays and Fuel Consumption

Science.gov (United States)

Li, Jinjian; Dridi, Mahjoub; El-Moudni, Abdellah

2016-01-01

The problem of reducing traffic delays and decreasing fuel consumption simultaneously in a network of intersections without traffic lights is solved by a cooperative traffic control algorithm, where the cooperation is executed based on the connection of Vehicle-to-Infrastructure (V2I). This resolution of the problem contains two main steps. The first step concerns the itinerary of which intersections are chosen by vehicles to arrive at their destination from their starting point. Based on the principle of minimal travel distance, each vehicle chooses its itinerary dynamically based on the traffic loads in the adjacent intersections. The second step is related to the following proposed cooperative procedures to allow vehicles to pass through each intersection rapidly and economically: on one hand, according to the real-time information sent by vehicles via V2I in the edge of the communication zone, each intersection applies Dynamic Programming (DP) to cooperatively optimize the vehicle passing sequence with minimal traffic delays so that the vehicles may rapidly pass the intersection under the relevant safety constraints; on the other hand, after receiving this sequence, each vehicle finds the optimal speed profiles with the minimal fuel consumption by an exhaustive search. The simulation results reveal that the proposed algorithm can significantly reduce both travel delays and fuel consumption compared with other papers under different traffic volumes. PMID:27999333

A Cooperative Traffic Control of Vehicle–Intersection (CTCVI for the Reduction of Traffic Delays and Fuel Consumption

Directory of Open Access Journals (Sweden)

Jinjian Li

2016-12-01

Full Text Available The problem of reducing traffic delays and decreasing fuel consumption simultaneously in a network of intersections without traffic lights is solved by a cooperative traffic control algorithm, where the cooperation is executed based on the connection of Vehicle-to-Infrastructure (V2I. This resolution of the problem contains two main steps. The first step concerns the itinerary of which intersections are chosen by vehicles to arrive at their destination from their starting point. Based on the principle of minimal travel distance, each vehicle chooses its itinerary dynamically based on the traffic loads in the adjacent intersections. The second step is related to the following proposed cooperative procedures to allow vehicles to pass through each intersection rapidly and economically: on one hand, according to the real-time information sent by vehicles via V2I in the edge of the communication zone, each intersection applies Dynamic Programming (DP to cooperatively optimize the vehicle passing sequence with minimal traffic delays so that the vehicles may rapidly pass the intersection under the relevant safety constraints; on the other hand, after receiving this sequence, each vehicle finds the optimal speed profiles with the minimal fuel consumption by an exhaustive search. The simulation results reveal that the proposed algorithm can significantly reduce both travel delays and fuel consumption compared with other papers under different traffic volumes.

Legal aspects of motor traffic trauma in Sri Lanka

Directory of Open Access Journals (Sweden)

Clifford Perera

2016-12-01

Legislation plays a critical role in regulating motor traffic in a country. The Motor Traffic Act of Sri Lanka has undergone many revisions in the recent past to accommodate new provisions to regularize road traffic effectively. However implementation of such provisions is heavily dependent on the rapid and effective action of the police on road traffic offences and awareness and attitudes of courts towards penalizing offenders in view of streamlining the legislation on road traffic.

Evaluation of Deterministic and Stochastic Components of Traffic Counts

Directory of Open Access Journals (Sweden)

Ivan Bošnjak

2012-10-01

Full Text Available Traffic counts or statistical evidence of the traffic processare often a characteristic of time-series data. In this paper fundamentalproblem of estimating deterministic and stochasticcomponents of a traffic process are considered, in the context of"generalised traffic modelling". Different methods for identificationand/or elimination of the trend and seasonal componentsare applied for concrete traffic counts. Further investigationsand applications of ARIMA models, Hilbert space formulationsand state-space representations are suggested.

Traffic and related self-driven many-particle systems

Science.gov (United States)

Helbing, Dirk

2001-10-01

Since the subject of traffic dynamics has captured the interest of physicists, many surprising effects have been revealed and explained. Some of the questions now understood are the following: Why are vehicles sometimes stopped by ``phantom traffic jams'' even though drivers all like to drive fast? What are the mechanisms behind stop-and-go traffic? Why are there several different kinds of congestion, and how are they related? Why do most traffic jams occur considerably before the road capacity is reached? Can a temporary reduction in the volume of traffic cause a lasting traffic jam? Under which conditions can speed limits speed up traffic? Why do pedestrians moving in opposite directions normally organize into lanes, while similar systems ``freeze by heating''? All of these questions have been answered by applying and extending methods from statistical physics and nonlinear dynamics to self-driven many-particle systems. This article considers the empirical data and then reviews the main approaches to modeling pedestrian and vehicle traffic. These include microscopic (particle-based), mesoscopic (gas-kinetic), and macroscopic (fluid-dynamic) models. Attention is also paid to the formulation of a micro-macro link, to aspects of universality, and to other unifying concepts, such as a general modeling framework for self-driven many-particle systems, including spin systems. While the primary focus is upon vehicle and pedestrian traffic, applications to biological or socio-economic systems such as bacterial colonies, flocks of birds, panics, and stock market dynamics are touched upon as well.

Towards a Cloud Based Smart Traffic Management Framework

Science.gov (United States)

Rahimi, M. M.; Hakimpour, F.

2017-09-01

Traffic big data has brought many opportunities for traffic management applications. However several challenges like heterogeneity, storage, management, processing and analysis of traffic big data may hinder their efficient and real-time applications. All these challenges call for well-adapted distributed framework for smart traffic management that can efficiently handle big traffic data integration, indexing, query processing, mining and analysis. In this paper, we present a novel, distributed, scalable and efficient framework for traffic management applications. The proposed cloud computing based framework can answer technical challenges for efficient and real-time storage, management, process and analyse of traffic big data. For evaluation of the framework, we have used OpenStreetMap (OSM) real trajectories and road network on a distributed environment. Our evaluation results indicate that speed of data importing to this framework exceeds 8000 records per second when the size of datasets is near to 5 million. We also evaluate performance of data retrieval in our proposed framework. The data retrieval speed exceeds 15000 records per second when the size of datasets is near to 5 million. We have also evaluated scalability and performance of our proposed framework using parallelisation of a critical pre-analysis in transportation applications. The results show that proposed framework achieves considerable performance and efficiency in traffic management applications.

Traffic mortality and the role of minor roads.

Science.gov (United States)

van Langevelde, Frank; van Dooremalen, Coby; Jaarsma, Catharinus F

2009-01-01

Roads have large impacts on wildlife, as they form one of the principal causes of mortality, and disturbance and fragmentation of habitat. These impacts are mainly studied and mitigated on major roads. It is, however, a widespread misconception that most animals are killed on major roads. In this paper, we argue that minor roads have a larger impact on wildlife with respect to habitat destruction, noise load and traffic mortality. We use data on traffic related deaths in badgers (Meles meles) in The Netherlands to illustrate that traffic mortality is higher on minor roads. We ask for a more extensive investigation of the environmental impacts of minor roads. Moreover, we argue that the success of mitigation on roads drastically increases when both major and minor roads are integrated in the planning of traffic flows. Therefore, we propose a strategy based on the concept of a "traffic-calmed area". Traffic-calmed areas create opportunities for wildlife by decreasing limitations for animal movement. We ask for further studies to estimate what size traffic-calmed areas should be to maintain minimum viable animal populations.

Improvement of driving safety in road traffic system

Science.gov (United States)

Li, Ke-Ping; Gao, Zi-You

2005-05-01

A road traffic system is a complex system in which humans participate directly. In this system, human factors play a very important role. In this paper, a kind of control signal is designated at a given site (i.e., signal point) of the road. Under the effect of the control signal, the drivers will decrease their velocities when their vehicles pass the signal point. Our aim is to transit the traffic flow states from disorder to order and then improve the traffic safety. We have tested this technique for the two-lane traffic model that is based on the deterministic Nagel-Schreckenberg (NaSch) traffic model. The simulation results indicate that the traffic flow states can be transited from disorder to order. Different order states can be observed in the system and these states are safer.

Long-range correlation analysis of urban traffic data

International Nuclear Information System (INIS)

Peng, Sheng; Jun-Feng, Wang; Shu-Long, Zhao; Tie-Qiao, Tang

2010-01-01

This paper investigates urban traffic data by analysing the long-range correlation with detrended fluctuation analysis. Through a large number of real data collected by the travel time detection system in Beijing, the variation of flow in different time periods and intersections is studied. According to the long-range correlation in different time scales, it mainly discusses the effect of intersection location in road net, people activity customs and special traffic controls on urban traffic flow. As demonstrated by the obtained results, the urban traffic flow represents three-phase characters similar to highway traffic. Moreover, compared by the two groups of data obtained before and after the special traffic restrictions (vehicles with special numbered plates only run in a special workday) enforcement, it indicates that the rules not only reduce the flow but also avoid irregular fluctuation. (general)

Coordinated Traffic Incident and Congestion Management (TIM-CM) : Mitigating Regional Impacts of Major Traffic Incidents in the Seattle I-5 Corridor

Science.gov (United States)

2018-02-02

Within the Seattle metropolitan area, traffic incident management (TIM) operations provide a multi-jurisdictional and coordinated strategy to detect, respond to, and clear traffic incidents so that traffic flow can be restored quickly and safely. The...

Safeguards of Neurotransmission: Endocytic Adaptors as Regulators of Synaptic Vesicle Composition and Function

Directory of Open Access Journals (Sweden)

Natalie Kaempf

2017-10-01

Full Text Available Communication between neurons relies on neurotransmitters which are released from synaptic vesicles (SVs upon Ca2+ stimuli. To efficiently load neurotransmitters, sense the rise in intracellular Ca2+ and fuse with the presynaptic membrane, SVs need to be equipped with a stringently controlled set of transmembrane proteins. In fact, changes in SV protein composition quickly compromise neurotransmission and most prominently give rise to epileptic seizures. During exocytosis SVs fully collapse into the presynaptic membrane and consequently have to be replenished to sustain neurotransmission. Therefore, surface-stranded SV proteins have to be efficiently retrieved post-fusion to be used for the generation of a new set of fully functional SVs, a process in which dedicated endocytic sorting adaptors play a crucial role. The question of how the precise reformation of SVs is achieved is intimately linked to how SV membranes are retrieved. For a long time both processes were believed to be two sides of the same coin since Clathrin-mediated endocytosis (CME, the proposed predominant SV recycling mode, will jointly retrieve SV membranes and proteins. However, with the recent proposal of Clathrin-independent SV recycling pathways SV membrane retrieval and SV reformation turn into separable events. This review highlights the progress made in unraveling the molecular mechanisms mediating the high-fidelity retrieval of SV proteins and discusses how the gathered knowledge about SV protein recycling fits in with the new notions of SV membrane endocytosis.

An Efficient Traffic Congestion Monitoring System on Internet of Vehicles

Directory of Open Access Journals (Sweden)

Duc-Binh Nguyen

2018-01-01

Full Text Available Existing intelligent transport systems (ITS do not fully consider and resolve accuracy, instantaneity, and compatibility challenges while resolving traffic congestion in Internet of Vehicles (IoV environments. This paper proposes a traffic congestion monitoring system, which includes data collection, segmented structure establishment, traffic-flow modelling, local segment traffic congestion prediction, and origin-destination traffic congestion service for drivers. Macroscopic model-based traffic-flow factors were formalized on the basis of the analysis results. Fuzzy rules-based local segment traffic congestion prediction was performed to determine the traffic congestion state. To enhance prediction efficiency, this paper presents a verification process for minimizing false predictions which is based on the Rankine-Hugoniot condition and an origin-destination traffic congestion service is also provided. To verify the feasibility of the proposed system, a prototype was implemented. The experimental results demonstrate that the proposed scheme can effectively monitor traffic congestion in terms of accuracy and system response time.

Overcoming Therapeutic Inertia in Multiple Sclerosis Care: A Pilot Randomized Trial Applying the Traffic Light System in Medical Education

Directory of Open Access Journals (Sweden)

Gustavo Saposnik

2017-08-01

Full Text Available BackgroundPhysicians often do not initiate or intensify treatments when clearly warranted, a phenomenon known as therapeutic inertia (TI. Limited information is available on educational interventions to ameliorate knowledge-to-action gaps in TI.ObjectivesTo evaluate the feasibility and efficacy of an educational intervention compared to usual care among practicing neurologists caring for patients with multiple sclerosis (MS.MethodsWe conducted a pilot double-blind, parallel-group, randomized clinical trial. Inclusion criteria included neurologists who are actively involved in managing MS patients. Participants were exposed to 20 simulated case-scenarios (10 cases at baseline, and 10 cases post-randomization to usual care vs. educational intervention of relapsing–remitting MS with moderate or high risk of disease progression. The educational intervention employed a traffic light system (TLS to facilitate decisions, allowing participants to easily recognize high-risk scenarios requiring treatment escalation. We also measured differences between blocks to invoke decision fatigue. The control group responded as they would do in their usual clinical practice not exposed to the educational intervention. The primary feasibility outcome was the proportion of participants who completed the study and the proportion of participants who correctly identified a high-risk case-scenario with the “red traffic light.” Secondary outcomes included decision fatigue (defined as an increment of TI in the second block of case-scenarios compared to the first block and the efficacy of the educational intervention measured as a reduction in TI for MS treatment.ResultsOf 30 neurologists invited to be part of the study, the participation rate was 83.3% (n = 25. Of the 25 participants, 14 were randomly assigned to the control group and 11 to the intervention group. TI was present in 72.0% of participants in at least one case scenario. For the primary feasibility

Strategic Framework of Air Traffic Development

Directory of Open Access Journals (Sweden)

Sanja Steiner

2008-05-01

Full Text Available The paper elaborates the past development of air traffic inEurope from the aspect of its economic benefits and ecologicallack of sustainability of conventional technology. The mainguidelines of the strategic development are related to the implementationof the global ecological standard and actual reformationprocesses of the air traffic management system postulatedby A TM 2000+ Strategy and the "Single European Sky"standard. The paper studies the wider aspects of integrated trafficdevelopment at the regional level and the factors influencingfurther development of the European air traffic.

31 CFR 594.301 - Blocked account; blocked property.

Science.gov (United States)

2010-07-01

... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.301 Blocked account; blocked property. The terms blocked account and...

On vehicular traffic data analysis

Energy Technology Data Exchange (ETDEWEB)

Brics, Martins; Mahnke, Reinhard [Institute of Physics, Rostock University (Germany)

2011-07-01

This contribution consists of analysis of empirical vehicular traffic flow data. The main focus lies on the Next Generation Simulation (NGSIM) data. The first findings show that there are artificial structures within the data due to errors of monitoring as well as smoothing position measurement data. As a result speed data show discretisation in 5 feet per second. The aim of this investigation is to construct microscopic traffic flow models which are in agreement to the analysed empirical data. The ongoing work follows the subject of research summarized by Christof Liebe in his PhD thesis entitled ''Physics of traffic flow: Empirical data and dynamical models'' (Rostock, 2010).

ACCOUNT OF ROAD CONDITIONS WHILE INVESTIGATING TRAFFIC ACCIDENTS

Directory of Open Access Journals (Sweden)

D. D. Selioukov

2010-01-01

Full Text Available The paper considers problems on better traffic safety at government, authority, engineering and driver activity levels, account of road conditions while investigating traffic accidents. The paper also provides road defects mentioned in forensic transport examinations of traffic accidents.

A Wavelet Analysis Approach for Categorizing Air Traffic Behavior

Science.gov (United States)

Drew, Michael; Sheth, Kapil

2015-01-01

In this paper two frequency domain techniques are applied to air traffic analysis. The Continuous Wavelet Transform (CWT), like the Fourier Transform, is shown to identify changes in historical traffic patterns caused by Traffic Management Initiatives (TMIs) and weather with the added benefit of detecting when in time those changes take place. Next, with the expectation that it could detect anomalies in the network and indicate the extent to which they affect traffic flows, the Spectral Graph Wavelet Transform (SGWT) is applied to a center based graph model of air traffic. When applied to simulations based on historical flight plans, it identified the traffic flows between centers that have the greatest impact on either neighboring flows, or flows between centers many centers away. Like the CWT, however, it can be difficult to interpret SGWT results and relate them to simulations where major TMIs are implemented, and more research may be warranted in this area. These frequency analysis techniques can detect off-nominal air traffic behavior, but due to the nature of air traffic time series data, so far they prove difficult to apply in a way that provides significant insight or specific identification of traffic patterns.

Admission Control of Integrated Voice and Data CDMA／TDD System Considering Asymmetric Traffic and Power Limit

Institute of Scientific and Technical Information of China (English)

CAOYanbo; ZHOUBin; LIChengshu

2004-01-01

In this paper, we research an admission control scheme of integrated voice and data CDMA/TDD (Code division multiple access/Time division duplex) system considering asymmetric traffic and power limit. A new user can access the system only if the outage probabilities it experiences on the uplink and downlink time slots are below a threshold value. Based on the power limit the results show the voice and data blocking probabilities under different cell coverage~ arrival rates and various uplink/downlink time slot allocation patterns. Furthermore, multicode and multislot schemes are also evaluated under the presented admission control scheme.

Design and Development of Biometric Traffic Offence System (BTOS ...

African Journals Online (AJOL)

The study was about the design and development of Biometric Traffic Offence System (BTOS) that would ease storage and retrieval of traffic offence cases in the Federal Road Safety Commission (FRSC) and the Traffic department of Nigeria Police force. The method used to manage traffic cases is manual; information ...

Traffic flow dynamics data, models and simulation

CERN Document Server

Treiber, Martin

2013-01-01

This textbook provides a comprehensive and instructive coverage of vehicular traffic flow dynamics and modeling. It makes this fascinating interdisciplinary topic, which to date was only documented in parts by specialized monographs, accessible to a broad readership. Numerous figures and problems with solutions help the reader to quickly understand and practice the presented concepts. This book is targeted at students of physics and traffic engineering and, more generally, also at students and professionals in computer science, mathematics, and interdisciplinary topics. It also offers material for project work in programming and simulation at college and university level. The main part, after presenting different categories of traffic data, is devoted to a mathematical description of the dynamics of traffic flow, covering macroscopic models which describe traffic in terms of density, as well as microscopic many-particle models in which each particle corresponds to a vehicle and its driver. Focus chapters on ...

32 CFR 634.29 - Traffic accident investigation reports.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Traffic accident investigation reports. 634.29... records. Installation law enforcement officials will record traffic accident investigations on Service/DLA... traffic accident investigation reports pertaining to accidents investigated by military police that...

Traffic modelling for Big Data backed telecom cloud

OpenAIRE

Via Baraldés, Anna

2016-01-01

The objective of this project is to provide traffic models based on new services characteristics. Specifically, we focus on modelling the traffic between origin-destination node pairs (also known as OD pairs) in a telecom network. Two use cases are distinguished: i) traffic generation in the context of simulation, and ii) traffic modelling for prediction in the context of big-data backed telecom cloud systems. To this aim, several machine learning and statistical models and technics are studi...

ROAD TRAFFIC ESTIMATION USING BLUETOOTH SENSORS

Directory of Open Access Journals (Sweden)

Monika N. BUGDOL

2017-09-01

Full Text Available The Bluetooth standard is a low-cost, very popular communication protocol offering a wide range of applications in many fields. In this paper, a novel system for road traffic estimation using Bluetooth sensors has been presented. The system consists of three main modules: filtration, statistical analysis of historical, and traffic estimation and prediction. The filtration module is responsible for the classification of road users and detecting measurements that should be removed. Traffic estimation has been performed on the basis of the data collected by Bluetooth measuring devices and information on external conditions (e.g., temperature, all of which have been gathered in the city of Bielsko-Biala (Poland. The obtained results are very promising. The smallest average relative error between the number of cars estimated by the model and the actual traffic was less than 10%.

What is required to guarantee data quality for regional traffic management. Implementation of traffic data quality management in the Middle Netherlands

NARCIS (Netherlands)

Seelen, P.A.G.; Vrancken, J.L.M.

2013-01-01

VERDER, a partnership of different governmental organizations in the Middle Netherlands, initiated different projects for regional traffic management to better use existing road capacity and safeguard mobility in the Middle Netherlands. This active form of traffic management requires traffic data

Estimation of urban traffic density from street camera images

OpenAIRE

Chandrakaladharan, Shreyas

2017-01-01

Traffic is a very real problem in today’s world. Elon Musk, CEO of SpaceX and Tesla, has created a start-up which aims to bore tunnels to better manage traffic. While we do not dare to challenge him, we propose to better manage traffic on roads by leveraging currently available technologies in a novel way. Our project aims to give accurate real-time predictions of traffic, so that prospective commuters can choose routes that are free of traffic, thereby automatically balanci...

Pro CSS for High Traffic Websites

CERN Document Server

Kennedy, A

2011-01-01

Although web standards-based websites can scale effectively - and basic CSS will give you basic results - there are considerations and obstacles that high traffic websites must face to keep your development and hosting costs to a minimum. There are many tips and tricks, as well as down-to-earth best practice information, to make sure that everything runs quickly and efficiently with the minimum amount of fuss or developer intervention. Targeted at "high traffic" websites - those receiving over 10,000 unique visitors a day - Pro CSS for High Traffic Websites gives you inside informati

NEW POSSIBILITIES OF RAILWAY TRAFFIC CONTROL SYSTEMS

Directory of Open Access Journals (Sweden)

Lionginas LIUDVINAVIČIUS

2016-06-01

Full Text Available This article analyses the train traffic control systems in 1435 mm and 1520 mm gauge railways. The article analyses the aspects of train traffic control and locomotive energy saving by using the coordinates of track profile change that have been received from GPS. In the article, achievements of Lithuanian railways (LG in the area of train traffic control optimisation are presented.

Active Traffic Capture for Network Forensics

Science.gov (United States)

Slaviero, Marco; Granova, Anna; Olivier, Martin

Network traffic capture is an integral part of network forensics, but current traffic capture techniques are typically passive in nature. Under heavy loads, it is possible for a sniffer to miss packets, which affects the quality of forensic evidence.

Citizen Science for Traffic Planning: A Practical Example

Science.gov (United States)

Rieke, Matthes; Stasch, Christoph; Autermann, Christian; de Wall, Arne; Remke, Albert; Wulffius, Herwig; Jirka, Simon

2017-04-01

Measures affecting traffic flows in urban areas, e.g. changing the configuration of traffic lights, are often causing emotional debates by citizens who are affected by these measures. Up to now, citizens are usually not involved in traffic planning and the evaluation of the decisions that were taken. The enviroCar project provides an open platform for collecting and analyzing car sensor data with GPS position data. On the hardware side, enviroCar relies on using Android smartphones and OBD-II Bluetooth adapters. A Web server component collects and aggregates the readings from the cars, anonymizes them and publishes the data as open data which scientists, public administrations or other third parties can utilize for further analysis. In this work, we provide a general overview on the enviroCar project and present a project in a mid-size city in Germany. The city's administration utilized the enviroCar platform with the help of a traffic system consultancy for including citizens in the evaluation process of different traffic light configurations along major traffic axes. Therefore, a public campaign was started including local workshops to engage the citizens. More than 150 citizens were actively collecting more about 9.500 tracks including about 2.5 million measurements. Dedicated evaluation results for the different traffic axes were computed based on the collected data set. Because the data is publicly available as open data, others may prove and reproduce the evaluation results contributing to an objective discussion of traffic planning measures. In summary, the project illustrates how Citizen Science methods and technologies improve traffic planning and related discussions.

BAD-LAMP defines a subset of early endocytic organelles in subpopulations of cortical projection neurons.

Science.gov (United States)

David, Alexandre; Tiveron, Marie-Catherine; Defays, Axel; Beclin, Christophe; Camosseto, Voahirana; Gatti, Evelina; Cremer, Harold; Pierre, Philippe

2007-01-15

The brain-associated LAMP-like molecule (BAD-LAMP) is a new member of the family of lysosome associated membrane proteins (LAMPs). In contrast to other LAMPs, which show a widespread expression, BAD-LAMP expression in mice is confined to the postnatal brain and therein to neuronal subpopulations in layers II/III and V of the neocortex. Onset of expression strictly parallels cortical synaptogenesis. In cortical neurons, the protein is found in defined clustered vesicles, which accumulate along neurites where it localizes with phosphorylated epitopes of neurofilament H. In primary neurons, BAD-LAMP is endocytosed, but is not found in classical lysosomal/endosomal compartments. Modification of BAD-LAMP by addition of GFP revealed a cryptic lysosomal retention motif, suggesting that the cytoplasmic tail of BAD-LAMP is actively interacting with, or modified by, molecules that promote its sorting away from lysosomes. Analysis of BAD-LAMP endocytosis in transfected HeLa cells provided evidence that the protein recycles to the plasma membrane through a dynamin/AP2-dependent mechanism. Thus, BAD-LAMP is an unconventional LAMP-like molecule and defines a new endocytic compartment in specific subtypes of cortical projection neurons. The striking correlation between the appearance of BAD-LAMP and cortical synatogenesis points towards a physiological role of this vesicular determinant for neuronal function.

TOWARDS A CLOUD BASED SMART TRAFFIC MANAGEMENT FRAMEWORK

Directory of Open Access Journals (Sweden)

M. M. Rahimi

2017-09-01

Full Text Available Traffic big data has brought many opportunities for traffic management applications. However several challenges like heterogeneity, storage, management, processing and analysis of traffic big data may hinder their efficient and real-time applications. All these challenges call for well-adapted distributed framework for smart traffic management that can efficiently handle big traffic data integration, indexing, query processing, mining and analysis. In this paper, we present a novel, distributed, scalable and efficient framework for traffic management applications. The proposed cloud computing based framework can answer technical challenges for efficient and real-time storage, management, process and analyse of traffic big data. For evaluation of the framework, we have used OpenStreetMap (OSM real trajectories and road network on a distributed environment. Our evaluation results indicate that speed of data importing to this framework exceeds 8000 records per second when the size of datasets is near to 5 million. We also evaluate performance of data retrieval in our proposed framework. The data retrieval speed exceeds 15000 records per second when the size of datasets is near to 5 million. We have also evaluated scalability and performance of our proposed framework using parallelisation of a critical pre-analysis in transportation applications. The results show that proposed framework achieves considerable performance and efficiency in traffic management applications.

The Development of the Multi-Center Traffic Management Advisor (MCTMA): Traffic Flow Management Research in a Multi-Facility Environment

Science.gov (United States)

Lee, Katharine K.; Davis, Thomas J.; Levin, Kerry M.; Rowe, Dennis W.

2001-01-01

The Traffic Management Advisor (TMA) is a decision-support tool for traffic managers and air traffic controllers that provides traffic flow visualization and other flow management tools. TMA creates an efficiently sequenced and safely spaced schedule for arrival traffic that meets but does not exceed specified airspace system constraints. TMA is being deployed at selected facilities throughout the National Airspace System in the US as part of the FAA's Free Flight Phase 1 program. TMA development and testing, and its current deployment, focuses on managing the arrival capacity for single major airports within single terminal areas and single en route centers. The next phase of development for this technology is the expansion of the TMA capability to complex facilities in which a terminal area or airport is fed by multiple en route centers, thus creating a multicenter TMA functionality. The focus of the multi-center TMA (McTMA) development is on the busy facilities in the Northeast comdor of the US. This paper describes the planning and development of McTMA and the challenges associated with adapting a successful traffic flow management tool for a very complex airspace.

Modelling of road traffic for traffic flow optimization of modern regional center as an example of Odessa

Directory of Open Access Journals (Sweden)

S.V. Myronenko

2016-12-01

Full Text Available At present sharply there is a problem of traffic management especially in big cities. The increase in the number of vehicles, both personal and public, led to congestion of city roads, many hours of traffic jams, difficulty of movement of pedestrians, increase the number of accidents, etc. Aim: The aim of the study is to evaluate the possibility of using simulation models to solve problems of analysis and optimization of traffic flows. To achieve this goal in a simulation environment the data base of the transport network will be developed. Materials and Methods: The problem of analysis and optimization of traffic flow is considered by the example of the city of Odessa (Ukraine, the results and recommendations can be easily adapted for other cities of Ukraine, and for the cities of most countries of the former socialist bloc. Features of transport systems make it impossible to build an adequate analytical model to explore options for the management of the system and its characteristic in different conditions. At the same time simulation modelling as a method to study such objects is a promising for the solution to this problem. As a simulation environment an OmniTRANS package as a universal tool for modeling of discrete, continuous and hybrid systems. Results: With OmniTRANS programs the model of traffic in Odessa was derived and the intensity of the traffic flow. B first approximation the transport network of the central district of the city was considered and built; without calibration and simulation it was developed a database of elements of the transport network and shown how it can be used to solve problems of analysis and optimization of traffic flows. Models constructed from elements of created database, allows you to change the level of detail of the simulated objects and phenomena, thereby obtaining models as macro and micro level.

Self-Similar Traffic In Wireless Networks

OpenAIRE

Jerjomins, R.; Petersons, E.

2005-01-01

Many studies have shown that traffic in Ethernet and other wired networks is self-similar. This paper reveals that wireless network traffic is also self-similar and long-range dependant by analyzing big amount of data captured from the wireless router.

Traffic control concepts for incident clearance

Science.gov (United States)

2009-01-01

This document discusses various aspects of traffic control for incidents with the focus on the traffic control roles and responsibilities of the responders as well as the safety of the responders and the motoring public. It also recognizes that activ...

Development and Evaluation of a Control System for Regional Traffic Management

Directory of Open Access Journals (Sweden)

John L. McLin

2011-01-01

Full Text Available Traffic congestion is a worsening problem in metropolitan areas which will require integrated regional traffic control systems to improve traffic conditions. This paper presents a regional traffic control system which can detect incident conditions and provide integrated traffic management during nonrecurrent congestion events. The system combines advanced artificial intelligence techniques with a traffic performance model based on HCM equations. Preliminary evaluation of the control system using traffic microsimulation demonstrates that it has the potential to improve system conditions during traffic incidents. In addition, several enhancements were identified which will make the system more robust in a real traffic control setting. An assessment of the control system elements indicates that there are no substantial technical barriers in implementing this system in a large traffic network.

["Habitual" left branch block alternating with 2 "disguised" bracnch block].

Science.gov (United States)

Lévy, S; Jullien, G; Mathieu, P; Mostefa, S; Gérard, R

1976-10-01

Two cases of alternating left bundle branch block and "masquerading block" (with left bundle branch morphology in the stnadard leads and right bundle branch block morphology in the precordial leads) were studied by serial tracings and his bundle electrocardiography. In case 1 "the masquerading" block was associated with a first degree AV block related to a prolongation of HV interval. This case is to our knowledge the first cas of alternating bundle branch block in which his bundle activity was recorded in man. In case 2, the patient had atrial fibrilation and His bundle recordings were performed while differents degrees of left bundle branch block were present: The mechanism of the alternation and the concept of "masquerading" block are discussed. It is suggested that this type of block represents a right bundle branch block associated with severe lesions of the "left system".

Traffic Adaptive MAC Protocols in Wireless Body Area Networks

Directory of Open Access Journals (Sweden)

Farhan Masud

2017-01-01

Full Text Available In Wireless Body Area Networks (WBANs, every healthcare application that is based on physical sensors is responsible for monitoring the vital signs data of patient. WBANs applications consist of heterogeneous and dynamic traffic loads. Routine patient’s observation is described as low-load traffic while an alarming situation that is unpredictable by nature is referred to as high-load traffic. This paper offers a thematic review of traffic adaptive Medium Access Control (MAC protocols in WBANs. First, we have categorized them based on their goals, methods, and metrics of evaluation. The Zigbee standard IEEE 802.15.4 and the baseline MAC IEEE 802.15.6 are also reviewed in terms of traffic adaptive approaches. Furthermore, a comparative analysis of the protocols is made and their performances are analyzed in terms of delay, packet delivery ratio (PDR, and energy consumption. The literature shows that no review work has been done on traffic adaptive MAC protocols in WBANs. This review work, therefore, could add enhancement to traffic adaptive MAC protocols and will stimulate a better way of solving the traffic adaptivity problem.

32 CFR 245.21 - ESCAT air traffic priority list.

Science.gov (United States)

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false ESCAT air traffic priority list. 245.21 Section 245.21 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PLAN FOR THE EMERGENCY SECURITY CONTROL OF AIR TRAFFIC (ESCAT) ESCAT Air Traffic Priority List (EATPL) § 245.21 ESCAT air traffic...

Traffic Noise Assessment at Residential Areas in Skudai, Johor

Science.gov (United States)

Sulaiman, F. S.; Darus, N.; Mashros, N.; Haron, Z.; Yahya, K.

2018-03-01

Vehicles passing by on roadways in residential areas may produce unpleasant traffic noise that affects the residents. This paper presents the traffic noise assessment of three selected residential areas located in Skudai, Johor. The objectives of this study are to evaluate traffic characteristics at selected residential areas, determine related noise indices, and assess impact of traffic noise. Traffic characteristics such as daily traffic volume and vehicle speed were evaluated using automatic traffic counter (ATC). Meanwhile, noise indices like equivalent continuous sound pressure level (LAeq), noise level exceeded 10% (L10) and 90% (L90) of measurement time were determined using sound level meter (SLM). Besides that, traffic noise index (TNI) and noise pollution level (LNP) were calculated based on the measured noise indices. The results showed an increase in noise level of 60 to 70 dBA maximum due to increase in traffic volume. There was also a significant change in noise level of more than 70 dBA even though average vehicle speed did not vary significantly. Nevertheless, LAeq, TNI, and LNP values for all sites during daytime were lower than the maximum recommended levels. Thus, residents in the three studied areas were not affected in terms of quality of life and health.

A Comparison of Traffic Operations among Beijing and Several International Megacities

Directory of Open Access Journals (Sweden)

Yuanzhou Yang

2011-12-01

Full Text Available High-Efficient traffic system is very important for economy and society of cities. Previous studies on the traffic comparison mostly took a city as a whole, but ignored the differences among areas inside the city. But in fact, the traffic congestion in different areas with a city is mostly different. Taking typical mega cities like Beijing, London, New York, and Tokyo as objects, this paper makes cross-comparison in the traffic operation and performance based on intelligent algorithm. Transportation infrastructure and travel demand data are discussed and unbalanced transport system is found in Beijing because of the conflict between too much traffic demand and defect road networks. From the aspects of traffic load, operational efficiency and safety, indexes including traffic v/c ratio, average vehicle speed and accident rate are selected to assess the performance of road traffic. It is concluded that road networks of Beijing have the worst performance compared with other three mega-cities and the primary reasons are the inappropriate distribution of utilization rate among the freeways, arterials, and local streets, and the high traffic concentration in urban area. So, several measures are recommended to improve the operation efficiency of traffic in Beijing especially for the green intelligent traffic system. Keywords: Traffic operation; Operational efficiency; Intelligent traffic system (ITS; Traffic load; traffic safety; Intelligent algorithm.

Traffic modelling validation of advanced driver assistance systems

NARCIS (Netherlands)

Tongeren, R. van; Gietelink, O.J.; Schutter, B. de; Verhaegen, M.

2007-01-01

This paper presents a microscopic traffic model for the validation of advanced driver assistance systems. This model describes single-lane traffic and is calibrated with data from a field operational test. To illustrate the use of the model, a Monte Carlo simulation of single-lane traffic scenarios

Traffic safety developments in Poland : a research note.

NARCIS (Netherlands)

Oppe, S.

2001-01-01

Recently there has been an increased interest in traffic safety in Poland. There is a feeling that the rapid growth of traffic should be accompanied by additional efforts to improve traffic safety, in order to stop the corresponding increase in fatalities and serious accidents. To set realistic

Model Predictive Control for Integrating Traffic Control Measures

NARCIS (Netherlands)

Hegyi, A.

2004-01-01

Dynamic traffic control measures, such as ramp metering and dynamic speed limits, can be used to better utilize the available road capacity. Due to the increasing traffic volumes and the increasing number of traffic jams the interaction between the control measures has increased such that local

Review on Driverless Traffic from Management Perspective

Directory of Open Access Journals (Sweden)

Chen Tingting

2017-01-01

Full Text Available The move towards automated driving is gaining ground. This paper reviews the development process of self-driving technology and discusses the safety and efficiency advantages of autonomous vehicles. The discussion shows that the existing traffic management system, including transport infrastructures and regulations, should be changed accordingly to maximize the advantages of autonomous driving. Thus, this paper subsequently gives an insight of the traffic management from three aspects: fully self-driving traffic infrastructures, mixed traffic infrastructures and regulations. First, it is summarized in detail what should be adjusted in intersections, parking lots, pedestrian crossings, ramps, signs and markings. With the transformation of traffic infrastructures, the advantages of driverless car will be more pronounced on account of increased capacity, reduced delay and land use. Also, this paper indicates that the implementations of strict product liability for self-driving car manufacturers and no-fault tort liability for users are applicable to automated vehicle accidents.

A Traffic Restriction Scheme for Enhancing Carpooling

Directory of Open Access Journals (Sweden)

Dong Ding

2017-01-01

Full Text Available For the purpose of alleviating traffic congestion, this paper proposes a scheme to encourage travelers to carpool by traffic restriction. By a variational inequity we describe travelers’ mode (solo driving and carpooling and route choice under user equilibrium principle in the context of fixed demand and detect the performance of a simple network with various restriction links, restriction proportions, and carpooling costs. Then the optimal traffic restriction scheme aiming at minimal total travel cost is designed through a bilevel program and applied to a Sioux Fall network example with genetic algorithm. According to various requirements, optimal restriction regions and proportions for restricted automobiles are captured. From the results it is found that traffic restriction scheme is possible to enhance carpooling and alleviate congestion. However, higher carpooling demand is not always helpful to the whole network. The topology of network, OD demand, and carpooling cost are included in the factors influencing the performance of the traffic system.

Automated Big Traffic Analytics for Cyber Security

OpenAIRE

Miao, Yuantian; Ruan, Zichan; Pan, Lei; Wang, Yu; Zhang, Jun; Xiang, Yang

2018-01-01

Network traffic analytics technology is a cornerstone for cyber security systems. We demonstrate its use through three popular and contemporary cyber security applications in intrusion detection, malware analysis and botnet detection. However, automated traffic analytics faces the challenges raised by big traffic data. In terms of big data's three characteristics --- volume, variety and velocity, we review three state of the art techniques to mitigate the key challenges including real-time tr...

Global collaboration on road traffic injury prevention.

Science.gov (United States)

Peden, Margie

2005-06-01

Worldwide, nearly 1.2 million people are killed in road traffic crashes every year and 20 million to 50 million more are injured or disabled. These injuries account for 2.1% of global mortality and 2.6% of all disability-adjusted life years (DALYs) lost. Low- and middle-income countries account for about 85% of the deaths and 90% of the DALYs lost annually. Without appropriate action, by 2020, road traffic injuries are predicted to be the third leading contributor to the global burden of disease. The economic cost of road traffic crashes is enormous. Globally it is estimated that US$518 billion is spent on road traffic crashes with low- and middle-income countries accounting for US$65 billion--more than these countries receive in development assistance. But these costs are just the tip of the iceberg. For everyone killed, injured or disabled by a road traffic crash there are countless others deeply affected. Many families are driven into poverty by the expenses of prolonged medical care, loss of a family breadwinner or the added burden of caring for the disabled. There is an urgent need for global collaboration on road traffic injury prevention. Since 2000, WHO has stepped up its response to the road safety crisis by firstly developing a 5-year strategy for road traffic injury prevention and following this by dedicating World Health Day 2004 to road safety and launching the WHO/World Bank World Report on Road Traffic Injury Prevention at the global World Health Day event in Paris, France. This short article highlights the main messages from the World Report and the six recommendations for action on road safety at a national and international level. It goes on to briefly discuss other international achievements since World Health Day and calls for countries to take up the challenge of implementing the recommendations of the World Report.

Consistency analysis of network traffic repositories

NARCIS (Netherlands)

Lastdrager, Elmer; Lastdrager, E.E.H.; Pras, Aiko

Traffic repositories with TCP/IP header information are very important for network analysis. Researchers often assume that such repositories reliably represent all traffic that has been flowing over the network; little thoughts are made regarding the consistency of these repositories. Still, for

A Brief Introduction of Air Traffic Management

Institute of Scientific and Technical Information of China (English)

1997-01-01

Air Traffic Management(ATM)started publication in 1995 by Air Traffic Management Bureauof CAAC.It is the first magazine about ATM field in CAAC.The chairman of Editorial Board ofATM is Mr.Bao Peide,Vice Minister of CAAC.Mr.Chen Ziye,Vice President of the 1st ResearchInstitute of CAAC and Chen Xuhua,General Director of Air Traffic Management Bureau are vicechairmen of the editorial board,and six general directors of local air traffic management bureau andsome professors and experts are members of the editorial board.ATM includes more than 20 columns,which are communication,navigation,surveillance,air trafficmanagement,special articles(policy,planning and management of implementation of CNS/ATM

The development of area wide traffic management scenarios

NARCIS (Netherlands)

Van Zuylen, H.J.; Lu, S.; Li, J.; Yusen, C.

2014-01-01

Traffic management in cities with congestion is a big challenge with still unused opportunities. Intersection control is a corner stone but this should be done in an area-wide context. The dominant traffic process on urban roads is the traffic flow on the intersections. Spill back is a most

E-Block: A Tangible Programming Tool with Graphical Blocks

Directory of Open Access Journals (Sweden)

Danli Wang

2013-01-01

Full Text Available This paper designs a tangible programming tool, E-Block, for children aged 5 to 9 to experience the preliminary understanding of programming by building blocks. With embedded artificial intelligence, the tool defines the programming blocks with the sensors as the input and enables children to write programs to complete the tasks in the computer. The symbol on the programming block's surface is used to help children understanding the function of each block. The sequence information is transferred to computer by microcomputers and then translated into semantic information. The system applies wireless and infrared technologies and provides user with feedbacks on both screen and programming blocks. Preliminary user studies using observation and user interview methods are shown for E-Block's prototype. The test results prove that E-Block is attractive to children and easy to learn and use. The project also highlights potential advantages of using single chip microcomputer (SCM technology to develop tangible programming tools for children.

Virtual Reality Game Education to Learn Traffic Regulation

OpenAIRE

Andru Deva Lukito

2017-01-01

Abstract – Traffic accident has become number 3 of children death cause in the world according to WHO[1]. Traffic accident that involve children often caused by their own by breaking the law or regulation. Therefor education about traffic regulation and law including traffic sign and its meaning must be given to children early. Because education means process to change a person or a group attitude and behavior in order to make them mature through teaching and training [2]. One of them that ca...

Multicast traffic grooming in flexible optical WDM networks

Science.gov (United States)

Patel, Ankitkumar N.; Ji, Philip N.; Jue, Jason P.; Wang, Ting

2012-12-01

In Metropolitan Area Networks (MANs), point-to-multipoint applications, such as IPTV, video-on-demand, distance learning, and content distribution, can be efficiently supported through light-tree-based multicastcommunications instead of lightpath-based unicast-communications. The application of multicasting for such traffic is justified by its inherent benefits of reduced control and management overhead and elimination of redundant resource provisioning. Supporting such multicast traffic in Flexible optical WDM (FWDM) networks that can provision light-trees using optimum amount of spectrum within flexible channel spacing leads to higher wavelength and spectral efficiencies compared to the conventional ITU-T fixed grid networks. However, in spite of such flexibility, the residual channel capacity of stranded channels may not be utilized if the network does not offer channels with arbitrary line rates. Additionally, the spectrum allocated to guard bands used to isolate finer granularity channels remains unutilized. These limitations can be addressed by using traffic grooming in which low-rate multicast connections are aggregated and switched over high capacity light-trees. In this paper, we address the multicast traffic grooming problem in FWDM networks, and propose a novel auxiliary graph-based algorithm for the first time. The performance of multicast traffic grooming is evaluated in terms of spectral, cost, and energy efficiencies compared to lightpath-based transparent FWDM networks, lightpathbased traffic grooming-capable FWDM networks, multicast-enabled transparent FWDM networks, and multicast traffic grooming-capable fixed grid networks. Simulation results demonstrate that multicast traffic grooming in FWDM networks not only improves spectral efficiency, but also cost, and energy efficiencies compared to other multicast traffic provisioning approaches of FWDM and fixed grid networks.

Usage of digital image correlation in assessment of behavior of block element pavement structure

Science.gov (United States)

Grygierek, M.; Grzesik, B.; Rokitowski, P.; Rusin, T.

2018-05-01

In diagnostics of existing road pavement structures deflection measurements have fundamental meaning, because of ability to assess present stiffness (bearing capacity) of whole layered construction. During test loading the reaction of pavement structure to applied load is measured in central point or in a few points located along a straight on a 1.5 ÷ 1.8 m distance (i.e. Falling Weight Deflectometer) in similar spacing equal to 20 ÷ 30 cm. Typical measuring techniques are productive and precise enough for most common pavement structures such as flexible, semi-rigid and rigid. It should be noted that in experimental research as well as in pavements in complex stress state, measurement techniques allowing observation of pavement deformation in 3D would have been very helpful. A great example of that type of pavements is a block element pavement structure consisting of i.e. paving blocks or stone slabs. Due to high stiffness and confined ability of cooperation of surrounding block elements, in that type of pavements fatigue life is strongly connected with displacement distribution. Unfortunately, typical deflection measurement methods forefend displacement observations and rotation of single block elements like paving blocks or slabs. Another difficult problem is to carry out unmistakable analysis of cooperation between neighboring elements. For more precise observations of displacements state of block element pavements under a wheel load a Digital Image Correlation (DIC) was used. Application of this method for assessment of behavior of stone slabs pavement under a traffic load enabled the monitoring of deformations distribution and encouraged to formulate conclusions about the initiation mechanism and development of damages in this type of pavement structures. Results shown in this article were obtained in field tests executed on an exploited pavement structure with a surface course made of granite slabs with dimensions 0.5x1.0x0.14 m.

Traffic dispersion through a series of signals with irregular split

Science.gov (United States)

Nagatani, Takashi

2016-01-01

We study the traffic behavior of a group of vehicles moving through a sequence of signals with irregular splits on a roadway. We present the stochastic model of vehicular traffic controlled by signals. The dynamic behavior of vehicular traffic is clarified by analyzing traffic pattern and travel time numerically. The group of vehicles breaks up more and more by the irregularity of signal's split. The traffic dispersion is induced by the irregular split. We show that the traffic dispersion depends highly on the cycle time and the strength of split's irregularity. Also, we study the traffic behavior through the series of signals at the green-wave strategy. The dependence of the travel time on offset time is derived for various values of cycle time. The region map of the traffic dispersion is shown in (cycle time, offset time)-space.

E-Block: A Tangible Programming Tool with Graphical Blocks

OpenAIRE

Danli Wang; Yang Zhang; Shengyong Chen

2013-01-01

This paper designs a tangible programming tool, E-Block, for children aged 5 to 9 to experience the preliminary understanding of programming by building blocks. With embedded artificial intelligence, the tool defines the programming blocks with the sensors as the input and enables children to write programs to complete the tasks in the computer. The symbol on the programming block's surface is used to help children understanding the function of each block. The sequence information is transfer...

The NASA Air Traffic Management Ontology (atmonto)

Data.gov (United States)

National Aeronautics and Space Administration — The NASA ATM (Air Traffic Management) Ontology describes classes, properties, and relationships relevant to the domain of air traffic management, and represents...

Traffic speed management

Directory of Open Access Journals (Sweden)

Subotić Jovana Lj.

2014-01-01

Full Text Available Speed, and vehicles themselves, affect the level of service and road safety, quality of life, noise from traffic, the environment, health, air pollution, emission of carbon dioxide, global warming, the economy and consumption of non-renewable energy such as oil. Therefore, the speed management of the traffic of multiple significance and that should be primarily to provide effective and economical conditions of the modern and preventive protection of human life as the greatest treasure and then the material resources. The way to accomplish this is by using various (different measures such as: appropriate planning and projecting roads and streets, speed control, the legislation, enforcement, campaigns, education, advanced technologies (ITS.

Navier-Stokes-like equations for traffic flow.

Science.gov (United States)

Velasco, R M; Marques, W

2005-10-01

The macroscopic traffic flow equations derived from the reduced Paveri-Fontana equation are closed starting with the maximization of the informational entropy. The homogeneous steady state taken as a reference is obtained for a specific model of the desired velocity and a kind of Chapman-Enskog method is developed to calculate the traffic pressure at the Navier-Stokes level. Numerical solution of the macroscopic traffic equations is obtained and its characteristics are analyzed.

Air pollution burden of illness from traffic in Toronto

International Nuclear Information System (INIS)

McKeown, D.; Campbell, M.; Bassil, K.; Morgan, C.; Lalani, M.; Macfarlane, R.; Bienefeld, M.

2007-11-01

This paper examined the health impacts of air pollution from traffic in Toronto. The paper provided a review of scientific studies on the health effects of vehicle pollution as well as a quantitative assessment of the economic costs and the burden of illness attributed to traffic pollution in Toronto. The report also assessed air pollution and traffic trends in the city, and outlined initiatives being conducted to reduce vehicle-related pollution. The study used the new air quality benefits tool (AQBAT) which determines the burden of illness and the economic impacts of traffic-related air pollution. Air modelling specialists were consulted in order to determine the contribution of traffic-related pollutants to overall pollution levels using data on traffic counts and vehicle emissions factors. The air model also considered dispersion, transport and and the transformation of compounds emitted from vehicles. Results of the study showed that traffic pollution caused approximately 440 premature deaths and 1700 hospitalizations per year. Children in the city experienced more than 1200 acute bronchitis episodes per year as a result of air pollution from traffic. Mortality-related costs associated with traffic pollution in Toronto were estimated at $2.2 billion. It was concluded that the city must pursue the implementation of sustainable transportation policies and programs which foster and enable the expansion and use of public transport. 47 refs., 8 tabs., 9 figs

GPS queues with heterogeneous traffic classes

NARCIS (Netherlands)

Borst, Sem; Mandjes, M.R.H.; van Uitert, Miranda

2002-01-01

We consider a queue fed by a mixture of light-tailed and heavy-tailed traffic. The two traffic classes are served in accordance with the generalized processor sharing (GPS) discipline. GPS-based scheduling algorithms, such as weighted fair queueing (WFQ), have emerged as an important mechanism for

Road traffic emission monitoring on motorways

NARCIS (Netherlands)

Dittrich, M.G.; Beek, P.J.G. van

2006-01-01

Road traffic noise is one of the major environmental noise sources that is known to cause health problems. Despite existing noise reception items, the continuing growth of traffic causes higher levels than the lims allow. Consequently, excessive costs are incurred for noise barriers along roads and

Multiagent reinforcement learning for urban traffic control using coordination graphs

NARCIS (Netherlands)

Kuyer, L.; Whiteson, S.; Bakker, B.; Vlassis, N.

2008-01-01

Since traffic jams are ubiquitous in the modern world, optimizing the behavior of traffic lights for efficient traffic flow is a critically important goal. Though most current traffic lights use simple heuristic protocols, more efficient controllers can be discovered automatically via multiagent

Streamlining Transportation Corridor Planning Processess: Freight and Traffic Information

Energy Technology Data Exchange (ETDEWEB)

Franzese, Oscar [ORNL

2010-08-01

The traffic investigation is one of the most important parts of an Environmental Impact Statement of projects involving the construction of new roadway facilities and/or the improvement of existing ones. The focus of the traffic analysis is on the determination of anticipated traffic flow characteristics of the proposed project, by the application of analytical methods that can be grouped under the umbrella of capacity analysis methodologies. In general, the main traffic parameter used in EISs to describe the quality of traffic flow is the Level of Service (LOS). The current state of the practice in terms of the traffic investigations for EISs has two main shortcomings. The first one is related to the information that is necessary to conduct the traffic analysis, and specifically to the lack of integration among the different transportation models and the sources of information that, in general, reside in GIS databases. A discussion of the benefits of integrating CRS&SI technologies and the transportation models used in the EIS traffic investigation is included. The second shortcoming is in the presentation of the results, both in terms of the appearance and formatting, as well as content. The presentation of traffic results (current and proposed) is discussed. This chapter also addresses the need of additional data, in terms of content and coverage. Regarding the former, other traffic parameters (e.g., delays) that are more meaningful to non-transportation experts than LOS, as well as additional information (e.g., freight flows) that can impact traffic conditions and safety are discussed. Spatial information technologies can decrease the negative effects of, and even eliminate, these shortcomings by making the relevant information that is input to the models more complete and readily available, and by providing the means to communicate the results in a more clear and efficient manner. The benefits that the application and use of CRS&SI technologies can provide to

Characterization of traffic-related PM concentration distribution and fluctuation patterns in near-highway urban residential street canyons.

Science.gov (United States)

Hahn, Intaek; Brixey, Laurie A; Wiener, Russell W; Henkle, Stacy W; Baldauf, Richard

2009-12-01

Analyses of outdoor traffic-related particulate matter (PM) concentration distribution and fluctuation patterns in urban street canyons within a microscale distance of less than 500 m from a highway source are presented as part of the results from the Brooklyn Traffic Real-Time Ambient Pollutant Penetration and Environmental Dispersion (B-TRAPPED) study. Various patterns of spatial and temporal changes in the street canyon PM concentrations were investigated using time-series data of real-time PM concentrations measured during multiple monitoring periods. Concurrent time-series data of local street canyon wind conditions and wind data from the John F. Kennedy (JFK) International Airport National Weather Service (NWS) were used to characterize the effects of various wind conditions on the behavior of street canyon PM concentrations.Our results suggest that wind direction may strongly influence time-averaged mean PM concentration distribution patterns in near-highway urban street canyons. The rooftop-level wind speeds were found to be strongly correlated with the PM concentration fluctuation intensities in the middle sections of the street blocks. The ambient turbulence generated by shifting local wind directions (angles) showed a good correlation with the PM concentration fluctuation intensities along the entire distance of the first and second street blocks only when the wind angle standard deviations were larger than 30 degrees. Within-canyon turbulent shearing, caused by fluctuating local street canyon wind speeds, showed no correlation with PM concentration fluctuation intensities. The time-averaged mean PM concentration distribution along the longitudinal distances of the street blocks when wind direction was mostly constantly parallel to the street was found to be similar to the distribution pattern for the entire monitoring period when wind direction fluctuated wildly. Finally, we showed that two different PM concentration metrics-time-averaged mean

Traffic noise control of a city

International Nuclear Information System (INIS)

Ahmed, A.; Khan, J.A.; Lakhani, A.H.; Hyder, F.G.; Shamsuddin, S.A.

2003-01-01

Long exposure to noise due to traffic affects our health and comfort. A noise level up to 45 dB is acceptable for the buildings in the city. A traffic noise study was conducted in Karachi at places of high traffic flow. The noise level was between 75-85 dB. Residential and commercial buildings had sound level up to 79 dB. Reducing vehicle noise by using proper muffler and acoustic treatment should first control traffic noise. Then noise can be reduced by 10-15 dB by constructing barriers of wood or concrete along roadside. Barrier height for sound attenuation can be found from Fresnel Number. The barrier reduces noise better if width at the top is increased and an inward bend of 60 degree is placed at the top. Where feasible a 4-5 meter high concrete barrier is recommended otherwise the nearby buildings from the road should be insulated and acoustically treated. (author)

Traffic signs recognition for driving assistance

Science.gov (United States)

Sai Sangram Reddy, Yatham; Karthik, Devareddy; Rana, Nikunj; Jasmine Pemeena Priyadarsini, M.; Rajini, G. K.; Naseera, Shaik

2017-11-01

In the current circumstances with the innovative headway, we must be able to provide assistance to the driving in recognising the traffic signs on the roads. At present time, many reviews are being directed moving in the direction of the usage of a keen Traffic Systems. One field of this exploration is driving support systems, and many reviews are being directed to create frameworks which distinguish and perceive street signs in front of the vehicle, and afterward utilize the data to advise the driver or to even control the vehicle by implementing this system on self-driving vehicles. In this paper we propose a method to detect the traffic sign board in a frame using HAAR cascading and then identifying the sign on it. The output may be either given out in voice or can be displayed as per the driver’s convenience. Each of the Traffic Sign is recognised using a database of images of symbols used to train the KNN classifier using open CV libraries.

Air Traffic Control Tools Assessment

Directory of Open Access Journals (Sweden)

Tomáš Noskievič

2017-04-01

Full Text Available Undoubtedly air transport in today’s world wouldn’t be able to exist without any air traffic control service. As the air transport has been coming through major changes and it has been expanding, it is assumed that its volume will be doubled in the next 15 years. Air traffic control uses strictly organised procedures to ensure safe course of air operations. With the skies covered with more airplanes every year, new tools must be introduced to allow the controllers to manage this rising amount of flying aircraft and to keep the air transport safe. This paper provides a comprehensive and organized material, which describes the newest tools and systems used by air traffic control officers. It proposes improvements for further research and development of ATC tools.

Detecting Distributed Network Traffic Anomaly with Network-Wide Correlation Analysis

Directory of Open Access Journals (Sweden)

Yang Dan

2008-12-01

Full Text Available Distributed network traffic anomaly refers to a traffic abnormal behavior involving many links of a network and caused by the same source (e.g., DDoS attack, worm propagation. The anomaly transiting in a single link might be unnoticeable and hard to detect, while the anomalous aggregation from many links can be prevailing, and does more harm to the networks. Aiming at the similar features of distributed traffic anomaly on many links, this paper proposes a network-wide detection method by performing anomalous correlation analysis of traffic signals' instantaneous parameters. In our method, traffic signals' instantaneous parameters are firstly computed, and their network-wide anomalous space is then extracted via traffic prediction. Finally, an anomaly is detected by a global correlation coefficient of anomalous space. Our evaluation using Abilene traffic traces demonstrates the excellent performance of this approach for distributed traffic anomaly detection.

Development of a Traffic Management Decision Support Tool for Freeway Incident Traffic Management (FITM) Plan Deployment : Research Summary

Science.gov (United States)

2017-12-01

In designing an effective traffic management plan for non-recurrent congestion, it is critical for responsible highway agencies to have some vital information, such as estimated incident duration, resulting traffic queues, and the expected delays. Ov...

Study on Driver Visual Physiological Characteristics in Urban Traffic

Directory of Open Access Journals (Sweden)

Fengyuan Wang

2014-01-01

Full Text Available In the integrated traffic environment, human factor is always a main factor of the three elementary factors, besides the vehicle and road factor. The driver physiological and psychological characteristics have an important impact especially on traffic safety in urban road traffic conditions. Some typical traffic scenes in condition of urban road, such as light signal control at intersection, overtaking, and passing, are selected for condition analysis. An eye movement apparatus was used to obtain driver eye closure, blink frequency, and other visual physiological indicators in the traffic conditions of urban road. The regular patterns of driver visual characteristics in the corresponding scenes were analyzed in detail to provide data and theoretical support for the further research on traffic safety of urban environment from the viewpoint of driver psychology and behavior.

A Driver Behavior Learning Framework for Enhancing Traffic Simulation

Directory of Open Access Journals (Sweden)

Ramona Maria Paven