WorldWideScience

Sample records for block exemption regulation

  1. The Influence of the Chicago School on the Commission's Guidelines, Notices and Block Exemption Regulations in EU Competition Policy

    DEFF Research Database (Denmark)

    Bartalevich, Dzmitry

    2016-01-01

    Antitrust rules are fundamentally informed and shaped by economic theories. Given the significance of EU competition policy for the European integration process, it is essential to disentangle the economic theories underlying EU competition law. There is abundant theoretical and empirical...... Commission incorporates Chicago School theory into EU competition law provisions. The analysis is carried out on the basis of the European Commission's guidelines, notices and block exemption regulations. The analysis reveals that the Commission does, to a considerable extent, follow the Chicago School...

  2. New Amendments Introduced to European Union Competition Law Due to the Expiration of Block Exemption Regulations Conference at Łazarski University. Report

    OpenAIRE

    Kozak, Małgorzata

    2011-01-01

    On 7 June 2010, a conference under the title New Amendments Introduced to European Union Competition Law Due to the Expiration of Block Exemption Regulations took place at the Lazarski University in Warsaw. The conference was opened by Professor Zbigniew Lasocik, the Dean of the Law Faculty of the Lazarski University, who started his speech by introducing the University and emphasizing the Faculty of Law’s aim to ensure high quality legal education.

  3. Making Waves in the Insurance Sector’s Safe Harbor: The European Commission Consults on the Insurance Block Exemption

    OpenAIRE

    John Pheasant; Anna Bicarregui

    2008-01-01

    It has been clear since the European Commission published its final report in relation to the business insurance sector inquiry in September 2007 that the Insurance Block Exemption Regulation was about to come under close scrutiny.

  4. 7 CFR 927.65 - Exemption from regulation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exemption from regulation. 927.65 Section 927.65 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... for either of such purposes from entering commercial channels of trade contrary to the provisions...

  5. 40 CFR 152.20 - Exemptions for pesticides adequately regulated by another Federal agency.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Exemptions for pesticides adequately... PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Exemptions § 152.20 Exemptions for pesticides adequately regulated by another Federal agency. The...

  6. 75 FR 66699 - Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles

    Science.gov (United States)

    2010-10-29

    ... published in the Federal Register (75 FR 46859-46861, Docket No. APHIS-2009-0018) a proposal to establish... Implementation Plan; Definitions for Exempt and Regulated Articles AGENCY: Animal and Plant Health...

  7. 78 FR 70191 - Post-Employment Conflict of Interest Regulations; Exempted Senior Employee Positions; Withdrawal...

    Science.gov (United States)

    2013-11-25

    ... From the Federal Register Online via the Government Publishing Office #0; #0;Rules and Regulations... / Monday, November 25, 2013 / Rules and Regulations#0;#0; ] OFFICE OF GOVERNMENT ETHICS 5 CFR Part 2641 RIN... Regulations; Exempted Senior Employee Positions'' published October 3, 2013, at 78 FR 61153. DATES:...

  8. 78 FR 12109 - Order Extending Temporary Exemptions From Certain Rules of Regulation SHO Related to Hurricane Sandy

    Science.gov (United States)

    2013-02-21

    ... COMMISSION Order Extending Temporary Exemptions From Certain Rules of Regulation SHO Related to Hurricane... seq. \\2\\ Order Granting Exemptions from Certain Rules of Regulation SHO Related to Hurricane Sandy... 36 of the Exchange Act authorizes the Commission, by rule, regulation, or order, to conditionally...

  9. 78 FR 78424 - Order Granting a Limited Exemption From Rule 102(a) of Regulation M to Certain Business...

    Science.gov (United States)

    2013-12-26

    ... COMMISSION Order Granting a Limited Exemption From Rule 102(a) of Regulation M to Certain Business Development Companies Pursuant to Rule 102(e) of Regulation M December 19, 2013. By letter dated December 19... Commission (``Commission'') issue an exemption from Rule 102 of Regulation M.\\2\\ Specifically, the...

  10. Exemption and clearance of radioactive waste from non-nuclear industry: A UK regulator's perspective

    International Nuclear Information System (INIS)

    In the UK radioactive substances are regulated by means of registrations and authorizations issued under the Radioactive Substances Act. For certain practices and types of radioactive materials, there are orders which allow exemption from registration/authorization, conditionally or unconditionally. The seventeen Exemption Orders in force cover a wide variety of types of radioactive materials and practices. Conditional Exemption Orders allow a degree of regulatory control without imposing undue burdens on users of radioactivity. For most orders, radiation doses to individuals would be about 1OμSv or less, and collective doses would be less than 1 man - Sievert. The UK is reviewing the exemption orders against the requirements of the 1996 Euratom Basic Safety Standards Directive. It intends to develop a coherent strategy for exemption and to rationalize the current orders. Recently there has been a degree of public concern over the release of items from the nuclear industry. Careful presentation of exemption and clearance concepts is necessary if public confidence in the regulatory system is to be maintained. (author)

  11. 78 FR 79286 - Truth in Lending (Regulation Z): Adjustment to Asset-Size Exemption Threshold

    Science.gov (United States)

    2013-12-30

    ... establish. In the 2013 Escrows Final Rule, 78 FR 4726 (January 22, 2013), the Bureau established such an... PROTECTION 12 CFR Part 1026 Truth in Lending (Regulation Z): Adjustment to Asset-Size Exemption Threshold... (Truth in Lending) to reflect a change in the asset size threshold for certain creditors to qualify...

  12. 76 FR 31415 - Federal Acquisition Regulation; Buy American Exemption for Commercial Information Technology...

    Science.gov (United States)

    2011-05-31

    ... 9000-AL62 Federal Acquisition Regulation; Buy American Exemption for Commercial Information Technology... from the Buy American Act for acquisition of information technology that is a commercial item. DATES: Effective Date: May 31, 2011. FOR FURTHER INFORMATION CONTACT: Ms. Cecelia L. Davis, Procurement Analyst,...

  13. 75 FR 60266 - Federal Acquisition Regulation; Buy American Exemption for Commercial Information Technology...

    Science.gov (United States)

    2010-09-29

    ... Regulation; Buy American Exemption for Commercial Information Technology--Construction Material AGENCIES... Act for acquisition of information technology that is a commercial item. DATES: Effective Date... the Buy American Act for acquisition of information technology that is a commercial item. This...

  14. 78 FR 40940 - Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles

    Science.gov (United States)

    2013-07-09

    ... Animal and Plant Health Inspection Service 7 CFR Part 357 RIN 0579-AD11 Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... and are threatened with extinction); and (iii) plants that are to remain planted or to be planted...

  15. 78 FR 61153 - Post-Employment Conflict of Interest Regulations; Exempted Senior Employee Positions

    Science.gov (United States)

    2013-10-03

    ... 3209-AA14 Post-Employment Conflict of Interest Regulations; Exempted Senior Employee Positions AGENCY...: Authority: 5 U.S.C. App. (Ethics in Government Act of 1978); 18 U.S.C. 207; E.O. 12674, 54 FR 15159, 3 CFR, 1989 Comp., p. 215, as modified by E.O. 12731, 55 FR 42547, 3 CFR, 1990 Comp., p. 306. 0 2....

  16. 78 FR 20032 - Styrene-Ethylene-Propylene Block Copolymer; Tolerance Exemption

    Science.gov (United States)

    2013-04-03

    .... No. 108388-87-0) when used as an inert ingredient in a pesticide formulation. AgroFresh Inc... permissible level for residues of styrene-ethylene-propylene block copolymer on food or feed commodities... code 111). Animal production (NAICS code 112). Food manufacturing (NAICS code 311)....

  17. 12 CFR 233.4 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... FUNDING OF UNLAWFUL INTERNET GAMBLING (REGULATION GG) § 233.4 Exemptions. (a) Automated clearing house... business are exempt from this regulation's requirements for establishing written policies and...

  18. Advanced Therapy Medicinal Products (ATMPand exemptions to the Regulation 1394/2007: how confident can we be? An exploratory analysis.

    Directory of Open Access Journals (Sweden)

    Philippe eVan Wilder

    2012-02-01

    Full Text Available The market authorisation procedure for medicinal products for human use is relying on their demonstrated efficacy, safety and pharmaceutical quality. This applies to all medicinal products whether of chemical or biological origin. Since October 2009, the first advanced therapy medicinal product (ATMP has been authorised through the centralized procedure. ATMPs are gene therapy medicinal products, somatic cell therapy medicinal products or tissue-engineered products.An appropriate ATMP- Regulation is dealing with ATMP requirements.Two exemptions are foreseen to the ATMP-Regulation: a. Products, which were legally on the Community market when the Regulation became applicable, should comply to the Regulation by 30 December 2012. b.the hospital exemption rule for non routine products for an individual patient. In this work we explored whether the actual application of the Regulation on ATMPs is in line with the aim of the Regulation in terms of guaranteeing the highest level of health protection for patients. Based on the analysis of the relative efficacy of the only EC authorized ATMP and its exempted alternatives, there is evidence against this Regulation 1394/2007 assumption.

  19. Advanced Therapy Medicinal Products and Exemptions to the Regulation 1394/2007: How Confident Can We be? An Exploratory Analysis.

    Science.gov (United States)

    Van Wilder, Philippe

    2012-01-01

    The market authorization procedure for medicinal products for human use is relying on their demonstrated efficacy, safety, and pharmaceutical quality. This applies to all medicinal products whether of chemical or biological origin. Since October 2009, the first advanced therapy medicinal product (ATMP) has been authorized through the centralized procedure. ATMPs are gene therapy medicinal products, somatic cell therapy medicinal products or tissue-engineered products. An appropriate ATMP - Regulation is dealing with ATMP requirements. Two exemptions are foreseen to the ATMP Regulation: (a) Products, which were legally on the Community market when the Regulation became applicable, should comply to the Regulation by December 30, 2012. (b) The hospital exemption rule for non-routine products for an individual patient. In this work we explored whether the actual application of the Regulation on ATMPs is in line with the aim of the Regulation in terms of guaranteeing the highest level of health protection for patients. Based on the analysis of the relative efficacy of the only EC authorized ATMP and its exempted alternatives, there is evidence against this Regulation 1394/2007 assumption.

  20. 12 CFR 203.3 - Exempt institutions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Exempt institutions. 203.3 Section 203.3 Banks... DISCLOSURE (REGULATION C) § 203.3 Exempt institutions. (a) Exemption based on state law. (1) A state-chartered or state-licensed financial institution is exempt from the requirements of this regulation if...

  1. Internet governance and global self regulation: theoretical and empirical building blocks for a general theory of self regulation

    NARCIS (Netherlands)

    Vey Mestdagh, C.; Rijgersberg, R.

    2010-01-01

    The following exposition sets out to identify the basic theoretical and empirical building blocks for a general theory of self-regulation. It uses the Internet as an empirical basis since its global reach and technical characteristics create interdependencies between actors that transcend national b

  2. Department of Transportation -- Exemption for using the Transuranic Package Transporter-I (TRUPACT-I) at the Idaho National Engineering Laboratory (Code of Federal Regulations, Title 49, Part 107, Subpart B -- Exemptions, 107-103 Application for Exemption)

    International Nuclear Information System (INIS)

    Exemption from specific regulations is being sought for the Transuranic Package Transporter Model I (TRUPACT-I) container. The design has successfully undergone extensive testing of a quarter-scale model and a full-scale prototype of the container. Results from the analysis and testing are in the TRUPACT-1 Safely Analysis Report for Packaging (SARP), GA-Al8695/SAND 87-7104 (TTC0735), April 1987 (see Attachment 1). The container was never certified or used because of questions raised during the certification process. Two features of the container design failed to satisfy the regulations for Type B packaging. First, the design utilizes a venting system to control internal and external pressures; this venting system is not allowed by the Code of Federal Regulations, Title 10, Parts 71(h) and 71.51(b) [10 CFR 71.(h) and 71.51(b)]. Second, the maximum quantity fissile material proposed to be hauled in TRUPACT-I exceeded the limits in 10 CFR 71.63(b) for a single-containment container. To correct these design deficiencies, the vents would be plugged during transport, and the maximum quantity of fissile material would be limited to the allowables for a single-containment container. An engineering analysis showed that the container could safely transport radioactive material within the boundaries of the Idaho National Engineering Laboratory (INEL) with the vent system plugged (see Attachment 2). However, some of the requirements for determining pressure on a container need to be changed (i.e., exempted) to reflect conditions unique to the INEL. The following are the requirements needing to be changed for INEL conditions, variances being sought, and justifications for the variances

  3. 49 CFR 350.343 - How may a State obtain a new exemption for State laws and regulations for a specific industry...

    Science.gov (United States)

    2010-10-01

    ... information supporting evaluation of the following 10 factors: (a) Type and scope of the industry exemption... laws and regulations for a specific industry involved in intrastate commerce? 350.343 Section 350.343... regulations for a specific industry involved in intrastate commerce? The FMCSA strongly discourages...

  4. 29 CFR 2580.412-27 - Exemption.

    Science.gov (United States)

    2010-07-01

    ... Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR... Exemptions Banking Institutions Subject to Federal Regulation § 2580.412-27 Exemption. An exemption from the... granted whereby banking institutions and trust companies specified in § 2580.412-28 are not required...

  5. 45 CFR 1705.12 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Exemptions. 1705.12 Section 1705.12 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE PRIVACY REGULATIONS § 1705.12 Exemptions. No Commission records system is exempted from the provisions...

  6. Regulation of Aquaporin Z osmotic permeability in ABA tri-block copolymer

    Directory of Open Access Journals (Sweden)

    Wenyuan Xie

    2015-08-01

    Full Text Available Aquaporins are transmembrane water channel proteins present in biological plasma membranes that aid in biological water filtration processes by transporting water molecules through at high speeds, while selectively blocking out other kinds of solutes. Aquaporin Z incorporated biomimetic membranes are envisaged to overcome the problem of high pressure needed, and holds great potential for use in water purification processes, giving high flux while keeping energy consumption low. The functionality of aquaporin Z in terms of osmotic permeability might be regulated by factors such as pH, temperature, crosslinking and hydrophobic thickness of the reconstituted bilayers. Hence, we reconstituted aquaporin Z into vesicles that are made from a series of amphiphilic block copolymers PMOXA-PDMS-PMOXAs with various hydrophobic molecular weights. The osmotic permeability of aquaporin Z in these vesicles was determined through a stopped-flow spectroscopy. In addition, the temperature and pH value of the vesicle solutions were adjusted within wide ranges to investigate the regulation of osmotic permeability of aquaporin Z through external conditions. Our results show that aquaporin Z permeability was enhanced by hydrophobic mismatch. In addition, the water filtration mechanism of aquaporin Z is significantly affected by the concentration of H+ and OH- ions.

  7. The U.S. Department of Energy's (DOE) response to requests for exemption from provisions of Title 10 code of Federal Regulations Part 835

    International Nuclear Information System (INIS)

    Following the issuance of Title 10 Code of Federal Regulations Part 835 (10 CFR 835), open-quotes Occupational Radiation Protection,close quotes in the Federal Register on 14 December 1993, all DOE facilities subject to the rule provisions were required to submit a radiation protection program that Sets forth the plans, schedules, and other measures for achieving compliance with the rule by 1 January 1996. Numerous DOE facilities identified areas of the rule where their facility needed either (1) a clarification of the intent and expectation of a provisions or (2) an exemption from the provisions. In response, the DOE Office of Worker Protection Programs and Hazards Management (EH-52) prepared and disseminated eight Radiological Control Technical Positions (RCTPs). These RCTPs provided clarifications of DOE's intent and expectations for compliance with specific provisions of the rule. EH-52 also processed requests for exemptions from provisions of 10 CFR 835 received from twelve different DOE facilities. The DOE issued 21 separate responses to these facilities, each one addressing the specific exepemtion request. Each response contained (1) an Exemption Decision and (2) a Technical Position discussing the basis for either denying or granting with conditions, as applicable, the exemption request

  8. 76 FR 37766 - Specified Commodities Imported Into the United States, Exempt From Import Regulations; Request...

    Science.gov (United States)

    2011-06-28

    ... import regulations: Avocados; grapefruit; kiwifruit; olives; oranges; fresh prunes; table grapes... imported for such outlets as processing, charity, animal feed, seed, and distribution to relief...

  9. Growth-Blocking Peptides As Nutrition-Sensitive Signals for Insulin Secretion and Body Size Regulation.

    Science.gov (United States)

    Koyama, Takashi; Mirth, Christen K

    2016-02-01

    In Drosophila, the fat body, functionally equivalent to the mammalian liver and adipocytes, plays a central role in regulating systemic growth in response to nutrition. The fat body senses intracellular amino acids through Target of Rapamycin (TOR) signaling, and produces an unidentified humoral factor(s) to regulate insulin-like peptide (ILP) synthesis and/or secretion in the insulin-producing cells. Here, we find that two peptides, Growth-Blocking Peptide (GBP1) and CG11395 (GBP2), are produced in the fat body in response to amino acids and TOR signaling. Reducing the expression of GBP1 and GBP2 (GBPs) specifically in the fat body results in smaller body size due to reduced growth rate. In addition, we found that GBPs stimulate ILP secretion from the insulin-producing cells, either directly or indirectly, thereby increasing insulin and insulin-like growth factor signaling activity throughout the body. Our findings fill an important gap in our understanding of how the fat body transmits nutritional information to the insulin producing cells to control body size. PMID:26928023

  10. 77 FR 63224 - Certifications and Exemptions Under the International Regulations for Preventing Collisions at...

    Science.gov (United States)

    2012-10-16

    ... Preventing Collisions at Sea, 1972 AGENCY: Department of the Navy, DoD. ACTION: Final rule. SUMMARY: The... Regulations for Preventing Collisions at Sea, 1972 (72 COLREGS), to reflect that the Deputy Assistant Judge... THE INTERNATIONAL REGULATIONS FOR PREVENTING COLLISIONS AT SEA, 1972 0 1. The authority citation...

  11. Regulation of methanol metabolism in the yeast Hansenula polymorpha. Isolation and characterization of mutants blocked in methanol assimilatory enzymes

    NARCIS (Netherlands)

    Koning, W. de; Gleeson, M.A.G.; Harder, W.; Dijkhuizen, L.

    1987-01-01

    A study of enzyme profiles in Hansenula polymorpha grown on various carbon substrates revealed that the synthesis of the methanol dissimilatory and assimilatory enzymes is regulated in the same way, namely by catabolite repression and induction by methanol. Mutants of H. polymorpha blocked in dihydr

  12. 77 FR 76839 - Home Mortgage Disclosure (Regulation C): Adjustment To Asset-Size Exemption Threshold

    Science.gov (United States)

    2012-12-31

    .... Procedural Requirements Administrative Procedure Act Under the Administrative Procedure Act (APA), notice and...) of the APA, the required publication or service of a substantive rule shall be made not less than 30...: PART 1003--HOME MORTGAGE DISCLOSURE (REGULATION C) 0 1. The authority citation for part 1003...

  13. 78 FR 43785 - Exemptive Order Regarding Compliance With Certain Swap Regulations

    Science.gov (United States)

    2013-07-22

    ... consist of: (1) Capital adequacy; (2) chief compliance officer; \\28\\ (3) risk management; \\29\\ (4) swap... 23.451. The Commission notes that it has not yet finalized regulations regarding capital adequacy or... regarding capital adequacy or margin and segregation for uncleared swaps before December 21, 2013,...

  14. 77 FR 74113 - Certifications and Exemptions Under the International Regulations for Preventing Collisions at...

    Science.gov (United States)

    2012-12-13

    ... Preventing Collisions at Sea, 1972 AGENCY: Department of the Navy, DoD. ACTION: Final rule. SUMMARY: The... Regulations for Preventing Collisions at Sea, 1972 (72 COLREGS), to reflect that the Deputy Assistant Judge... PREVENTING COLLISIONS AT SEA, 1972 0 1. The authority citation for part 706 continues to read as...

  15. 78 FR 40630 - International Traffic in Arms Regulations: Canadian Firearms Components Exemption

    Science.gov (United States)

    2013-07-08

    ... licensing for export to Canada of firearms components not exceeding $500 in value. DATES: This rule is... Appropriations Act 2013 (Pub. L. 113-6). The Department has the authority to regulate the export control program pursuant to the Arms Export Control Act, 22 U.S.C. 2778. Pursuant to section 520, the Department...

  16. Dietary fish oil blocks carcinogen-induced down-regulation of colonic protein kinase C isozymes.

    Science.gov (United States)

    Jiang, Y H; Lupton, J R; Chapkin, R S

    1997-02-01

    In order to elucidate the influence of dietary constituents on colonic intracellular signal transduction, the effect of different fats on rat colonic epithelial protein kinase C (PKC) alpha (classical), delta (novel) and lambda-zeta (atypical) expression was determined in carcinogen-treated animals. Sprague-Dawley rats were provided with one of two fats (corn oil and fish oil); plus or minus the carcinogen azoxymethane (AOM) and killed at two time points (15 and 37 weeks) in a 2x2x2 factorial design. At 5 and 6 weeks of age, animals were injected s.c. with either AOM at a dose of 15 mg/kg body weight or saline once a week for 2 weeks and continued on the same diet until termination of the study. At 15 and 37 weeks after the second injection, 10 rats from each treatment group were killed. Colonic PKC alpha, delta and lambda-zeta steady-state protein and mRNA levels were determined using immunoblotting and relative quantitative polymerase chain reaction, respectively. Colonic mucosa from rats injected with AOM had significantly suppressed membrane and cytosolic PKC alpha and cytosolic lambda-zeta protein levels (P fish oil diets had significantly higher (P protein levels relative to animals fed corn oil diets. However, the effect of diet and AOM on the steady-state expression of PKC alpha, delta and zeta mRNA was not consistent with changes in the respective isozyme protein levels, suggesting regulation at the post-transcriptional level. These data demonstrate that dietary fish oil blocks the carcinogen-induced decrease in the steady-state levels of colonic mucosal PKC delta and lambda-zeta, which may in part explain why this fat source protects against colon cancer development.

  17. Self-Regulation and Wellbeing When Facing a Blocked Parenthood Goal: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    da Silva, Sara Mesquita; Boivin, Jacky; Gameiro, Sofia

    2016-01-01

    Developmental regulation theories claim that continuing to pursue a goal when it becomes blocked contributes to poorer wellbeing. This consequence is expected to lead to the use of self-regulation strategies in the form of higher disengagement from the goal and higher reengagement in other meaningful goals. The use of these strategies is expected to lead to better wellbeing. A systematic-review and meta-analyses were conducted to test the major predictions of developmental regulation theories for blocked parenthood goal and to investigate possible moderator variables, particularly type and degree of blockage. A total of eight meta-analyses were performed using random-effects models. Moderation was tested with subgroup analysis. After searching eight databases, 4977 potential relevant manuscripts were identified but only six met inclusion criteria. From the eight meta-analyses conducted, only two were significant. In line with prediction, higher goal blockage was related to higher negative mood and reengagement in other life goals was associated to higher positive mood (p research had too many methodological limitations to reach firm conclusions. Future studies aimed at investigating blocked parenthood goal are required to evaluate the value of developmental regulation theories. PMID:27336597

  18. 29 CFR 2580.412-28 - Conditions of exemption.

    Science.gov (United States)

    2010-07-01

    ... BONDING RULES Exemptions Banking Institutions Subject to Federal Regulation § 2580.412-28 Conditions of exemption. This exemption applies only to those banking institutions and trust companies subject to... Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT...

  19. 78 FR 47818 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-08-06

    ... FR 3316). FOR FURTHER INFORMATION CONTACT: Elaine M. Papp, Chief, Medical Programs Division, (202... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  20. 48 CFR 2804.506 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Exemptions. 2804.506 Section 2804.506 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General ADMINISTRATIVE MATTERS Electronic Commerce in Contracting 2804.506 Exemptions. Pursuant to FAR 4.506(b),...

  1. 15 CFR 30.37 - Miscellaneous exemptions.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Miscellaneous exemptions. 30.37 Section 30.37 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From the Requirements for the...

  2. Self-Regulation and Wellbeing When Facing a Blocked Parenthood Goal: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    da Silva, Sara Mesquita; Boivin, Jacky; Gameiro, Sofia

    2016-01-01

    Developmental regulation theories claim that continuing to pursue a goal when it becomes blocked contributes to poorer wellbeing. This consequence is expected to lead to the use of self-regulation strategies in the form of higher disengagement from the goal and higher reengagement in other meaningful goals. The use of these strategies is expected to lead to better wellbeing. A systematic-review and meta-analyses were conducted to test the major predictions of developmental regulation theories for blocked parenthood goal and to investigate possible moderator variables, particularly type and degree of blockage. A total of eight meta-analyses were performed using random-effects models. Moderation was tested with subgroup analysis. After searching eight databases, 4977 potential relevant manuscripts were identified but only six met inclusion criteria. From the eight meta-analyses conducted, only two were significant. In line with prediction, higher goal blockage was related to higher negative mood and reengagement in other life goals was associated to higher positive mood (p < .001). From a total of eight subgroup analyses performed, results showed that disengaging had a positive impact on wellbeing for people experiencing an unanticipated type of blockage (i.e., infertility) but not for those with an anticipated one (i.e., postponing parenthood; X2 = 4.867, p = .03). From the total of twelve sensitivity analyses performed only one suggested that results might differ. The association between disengagement and mood varied according to study quality. When only average studies were included this association was negative, although non-significant. The evidence obtained did not fully support developmental regulation theories for the pursuit of parenthood goal, but primary research had too many methodological limitations to reach firm conclusions. Future studies aimed at investigating blocked parenthood goal are required to evaluate the value of developmental regulation

  3. Cervical sympathetic block regulates early systemic inflammatory response in severe trauma patients

    OpenAIRE

    Liu, Ming-Hua; Tian, Jun; Su, Yong-Ping; WANG, Tao; Xiang, Qiang; Wen, Liang

    2013-01-01

    Background This aim of this study was to investigate the effects of one-side cervical sympathetic block on early inflammatory response in severe trauma patients. Material/Methods Thirty severe trauma patients with injury severity score (ISS) of 16 to 25 were randomly divided into treatment and control groups (n=15 each). Patients in the treatment group underwent a right-side stellate ganglion block (SGB) using 8 mL 0.75% ropivacaine for 4 times, with the first injection within 12 hr of admiss...

  4. Blocking transforming growth factor- receptor signaling down-regulates transforming growth factor-β1 autoproduction in keloid fibroblasts

    Institute of Scientific and Technical Information of China (English)

    刘伟; 蔡泽浩; 王丹茹; 武小莉; 崔磊; 商庆新; 钱云良; 曹谊林

    2002-01-01

    Objective: To study transforming growth factor-β1(TGF-β1) autoproduction in keloid fibroblasts and theregulation effect of blocking TGF-β intracellular signalingon rhTGF-β1 autoproduction.Methods: Keloid fibroblasts cultured in vitro weretreated with either rhTGF-β1 (5 ng/ml ) or recombinantadenovirus containing a truncated type II TGF-β receptorgene (50 pfu/cell ). Their effects of regulating geneexpression of TGF-β1 and its receptor I and II wereobserved with Northern blot.Results: rhTGF-β1 up-regulated the gene expressionof TGF-β1 and receptor I, but not receptor II. Over-expression of the truncated receptor II down-regulated thegene expression of TGF-β1 and its receptor I, but notreceptor II.Conclusions: TGF-β1 autoproduction was observed inkeloid fibroblasts. Over-expression of the truncated TGF-βreceptor H decreased TGF-β1 autoproduction via blockingTGF-β receptor signaling.

  5. 26 CFR 1.501(a)-1 - Exemption from taxation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Exemption from taxation. 1.501(a)-1 Section 1.501... (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(a)-1 Exemption from taxation. (a) In... law or regulations or for other good cause, an organization that has been determined by...

  6. 48 CFR 252.229-7002 - Customs exemptions (Germany).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Customs exemptions... of Provisions And Clauses 252.229-7002 Customs exemptions (Germany). As prescribed in 229.402-70(b), use the following clause: Customs Exemptions (Germany) (JUN 1997) Imported products required for...

  7. Cyclosporin A does not block the phorbol ester - protein kinase C regulated pathway of T cell activation

    International Nuclear Information System (INIS)

    The T cell line Jurkat can be induced to produce interleukin-2 (IL-2) in vitro by a combination of two stimuli: (1) A stimulus that increases cytoplasmic free Ca++ concentration plus (2) phorbol ester (PMA). No. IL-2 production is induced with either stimulus alone. The T cell line HUT 78 responds to the same combination of stimuli, however also produces low amounts of IL-2 in response to PMA only. After HUT 78 cells were pretreated with the nucleoside analog 5-azacytidine (AZA) they produced maximal amounts of IL-2 in response to PMA alone. Cyclosporin A (CsA) has been shown to completely block the two stimulus-induced IL-2 production in Jurkat at a pretranslational level. In contrast, the low level of IL-2 production in HUT 78 and the high level of IL-2 production in AZA-treated HUT 78 induced by PMA only is not inhibited by CsA. Additionally we demonstrated that CsA did not inhibit activation of protein kinase C, the primary target enzyme in PMA induced cell activation. The presented data suggest that CsA does not globally block lymphokine expression but rather interferes with signaling events in T cell activation. It appears that CsA blocks the pathway controlled by either Ca++ alone or Ca++ in combination with PMA, but not activation signaling regulated by PMA induced activation of protein kinase C alone

  8. 17 CFR 247.776 - Exemption from the definition of “broker” for banks effecting certain excepted or exempted...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption from the definition of âbrokerâ for banks effecting certain excepted or exempted transactions in a company's securities... AND EXCHANGE COMMISSION (CONTINUED) REGULATION R-EXEMPTIONS AND DEFINITIONS RELATED TO THE...

  9. 29 CFR 2570.35 - Information to be included in applications for individual exemptions only.

    Science.gov (United States)

    2010-07-01

    ... exemptions only. 2570.35 Section 2570.35 Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS... be included in applications for individual exemptions only. (a) Except as provided in paragraph (c... consummated or will be consummated only if the exemption is granted; (14) If the exemption transaction...

  10. 49 CFR 1039.10 - Exemption of agricultural commodities except grain, soybeans, and sunflower seeds.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Exemption of agricultural commodities except grain... REGULATIONS EXEMPTIONS § 1039.10 Exemption of agricultural commodities except grain, soybeans, and sunflower seeds. The rail transportation of the commodities listed below is exempt from the provisions of...

  11. 7 CFR 985.58 - Exempt oil.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exempt oil. 985.58 Section 985.58 Agriculture... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Volume Limitations § 985.58 Exempt oil. Oil held by a producer or handler on the effective date of this subpart shall not...

  12. 29 CFR 780.329 - Exempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exempt work. 780.329 Section 780.329 Labor Regulations... AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture... Provisions § 780.329 Exempt work. (a) The standard that must be used to determine whether the...

  13. 22 CFR 503.8 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... Relations BROADCASTING BOARD OF GOVERNORS FREEDOM OF INFORMATION ACT REGULATION § 503.8 Exemptions. Section 552(b) of the Freedom of Information Act contains nine exemptions to the mandatory disclosure of... avoiding the public confusion that might result from disclosing reasons that were not in fact the...

  14. 34 CFR 5b.11 - Exempt systems.

    Science.gov (United States)

    2010-07-01

    ... Chief Information Officer, Regulatory Information Management Group, Washington, DC 20202-4651. (f... 34 Education 1 2010-07-01 2010-07-01 false Exempt systems. 5b.11 Section 5b.11 Education Office of the Secretary, Department of Education PRIVACY ACT REGULATIONS § 5b.11 Exempt systems. (a)...

  15. Ligand-responsive RNA switches: viral translation regulators, therapeutic targets, and tunable building blocks for nanotechnology

    OpenAIRE

    Boerneke, Mark A.

    2016-01-01

    Ligand-responsive RNA mechanical switches represent a new class of simple and small switching modules which regulate viral translation initiation by adopting well-defined ligand-free and bound conformational states without undergoing large secondary structure rearrangements, distinguishing them from metabolite-sensing riboswitches. Initially discovered in the internal ribosome entry site (IRES) of hepatitis C virus (HCV), RNA switch motifs have now been discovered in the genomes of diverse o...

  16. An evaluation of the exemption level for the radiation protection regulation based on the social risk acceptance in Korea

    International Nuclear Information System (INIS)

    Radiation protection is based not only on the science but also on the political, social, economical and emotional factors, so a policy decision for a factor like the exemption level in this field must be considered social expectation and valuation as well as scientific evaluation. In this paper, an attempt was made to get a rationale on the exemption level, which has a significant meaning in radiation protection, by means of surveying the social risk acceptance in Korea. Risk perception data were collected by mail surveys to the respondents randomly selected in the city of Seoul. A poor response rate, 156 out of 400, was observed. The result showed that the majority of the respondents agreed upon setting a de mini mis level of risk and the favoured de mini mis level appeared to be in the range of 10-6yr-1 to 10-7yr-1, which is consistent with the level suggested by other organizations: ICRP, EPA and NRPB. Approximately the same risk level, unfortunately, was obtained for the risk limits against a harmful agent, which makes no sense. It can be attributed to mis-communication due to the questionnaires inadequately designed. The acceptable risk level for a single practice was selected to be 1/100 or less of the risk limits, which seemed overly conservative, but could be understood in the light of the public attitude of outrage. There seems to be tendency that the public recognize the risk significant if it is not de mini mis. This study should not be regarded as one giving a satisfactory conclusion but a preliminary attempt to evaluate the acceptable risk level. More endeavors in design of questionnaires are needed to communicate successfully with the members of the public

  17. Basis for applying for exemption according to species protection regulation. Final repository for spent nuclear fuel at Forsmark; Underlag till ansoekan om dispens enligt artskyddsfoerordningen. Slutfoervar foer anvaent kaernbraensle i Forsmark

    Energy Technology Data Exchange (ETDEWEB)

    2011-02-15

    SKB will submit applications for permits and admissibility under the Environmental Act and under the Nuclear Activities Act to construct and operate a disposal facility for spent nuclear fuel at Forsmark. In the final repository the spent nuclear fuel from Swedish nuclear power plants is placed in order to protect human health and the environment against harmful effects of ionizing radiation. Construction and operation of the disposal facility in Forsmark will make an impact, give effects and consequences for the natural environment. Utilization of land for the construction of the facility and the impact on ground water as a result of groundwater drainage is expected to have negative consequences for the species included in species protection regulation. Thus, the planned activity require exemption from species protection regulation (SFS 2007:845). The purpose of this document is to provide a basis for an application for exemption under 14 paragraph species protection regulation from the prohibitions of 4, 6, 7 and 8 paragraph species protection regulation. A basis for the exemption application is that the proposed activity is considered to have an 'overriding public interest' prescribed in 14 paragraph species protection regulation. The document reports the impact, effects and consequences of the planned activities on species covered in the species protection regulation. The impact on protected species can be divided into two categories: - Direct effects on protected species and their habitats by utilization of the land. - Indirect effects on protected species and their habitats in the drainage of groundwater and the effect on groundwater levels. The document also includes a description of planned actions to prevent, restrict and compensate for the effects and consequences that the activity may cause. By applying for an exemption under 14 paragraph species protection regulation in a separate order from the application for permit according to chapters 9

  18. How Aromatic Compounds Block DNA Binding of HcaR Catabolite Regulator.

    Science.gov (United States)

    Kim, Youngchang; Joachimiak, Grazyna; Bigelow, Lance; Babnigg, Gyorgy; Joachimiak, Andrzej

    2016-06-17

    Bacterial catabolism of aromatic compounds from various sources including phenylpropanoids and flavonoids that are abundant in soil plays an important role in the recycling of carbon in the ecosystem. We have determined the crystal structures of apo-HcaR from Acinetobacter sp. ADP1, a MarR/SlyA transcription factor, in complexes with hydroxycinnamates and a specific DNA operator. The protein regulates the expression of the hca catabolic operon in Acinetobacter and related bacterial strains, allowing utilization of hydroxycinnamates as sole sources of carbon. HcaR binds multiple ligands, and as a result the transcription of genes encoding several catabolic enzymes is increased. The 1.9-2.4 Å resolution structures presented here explain how HcaR recognizes four ligands (ferulate, 3,4-dihydroxybenzoate, p-coumarate, and vanillin) using the same binding site. The ligand promiscuity appears to be an adaptation to match a broad specificity of hydroxycinnamate catabolic enzymes while responding to toxic thioester intermediates. Structures of apo-HcaR and in complex with a specific DNA hca operator when combined with binding studies of hydroxycinnamates show how aromatic ligands render HcaR unproductive in recognizing a specific DNA target. The current study contributes to a better understanding of the hca catabolic operon regulation mechanism by the transcription factor HcaR. PMID:27129205

  19. Doxycycline blocks gastric ulcer by regulating matrix metalloproteinase-2 activity and oxidative stress

    Institute of Scientific and Technical Information of China (English)

    Laishram Pradeepkumar Singh; Amartya Mishra; Debjit Saha; Snehasikta Swarnakar

    2011-01-01

    AIM: To examine the effect of doxycycline on the activity of matrix metalloproteinases (MMPs) and oxidative stress in gastric tissues of rats following gastric injury. METHODS: Gastric ulcers were generated in rats by administration of 70% ethanol, and activity of doxycycline was tested by administration 30 min prior to ethanol. Similarly, the effect of doxycycline was tested in an indomethacin-induced gastric ulcer model. The activities and expression of MMPs were examined by zymography and Western blot analysis. RESULTS: Gastric injury in rats as judged by elevated ulcer indices following exposure to ulcerogen, either indomethacin or ethanol, was reversed significantly by doxycycline. Indomethacin-induced ulcerated gastric tissues exhibited about 12-fold higher proMMP-9 activity and about 5-fold higher proMMP-3 activity as compared to control tissues. Similarly, ethanol induced about 22-fold and about 6-fold higher proMMP-9 and proMMP-3 activities, respectively, in rat gastric tissues. Both proMMP-9 and MMP-3 activities were markedly decreased by doxycycline in ulcerogen treated rat gastric tissues. In contrast, the reduced MMP-2 activity in ulcerated tissues was increased by doxycycline during ulcer prevention. On the other hand, doxycycline inhibited significantly proMMP-9, -2 and -3 activities in vitro . In addition, doxycycline reduced oxidative load in gastric tissues and scavenged H2O2 in vitro . Our results suggest a novel regulatory role of doxycycline on MMP-2 activity in addition to inhibitory action on MMP-9 and MMP-3 during prevention of gastric ulcers. CONCLUSION: This is the first demonstration of dual action of doxycycline, that is, regulation of MMP activity and reduction of oxidative stress in arresting gastric injury.

  20. Regulation of coenzyme Q biosynthesis in yeast: a new complex in the block.

    Science.gov (United States)

    González-Mariscal, Isabel; García-Testón, Elena; Padilla, Sergio; Martín-Montalvo, Alejandro; Pomares-Viciana, Teresa; Vazquez-Fonseca, Luis; Gandolfo-Domínguez, Pablo; Santos-Ocaña, Carlos

    2014-02-01

    Coenzyme Q (CoQ) is an isoprenylated benzoquinone found in mitochondria, which functions mainly as an electron carrier from complex I or II to complex III in the inner membrane. CoQ is also an antioxidant that specifically prevents the oxidation of lipoproteins and the plasma membrane. Most of the information about the synthesis of CoQ comes from studies performed in Saccharomyces cerevisiae. CoQ biosynthesis is a highly regulated process of sequential modifications of the benzene ring. There are three pieces of evidence supporting the involvement of a multienzymatic complex in yeast CoQ6 biosynthesis: (a) the accumulation of a unique early precursor in all null mutants of the COQ genes series, 4-hydroxy-3-hexaprenyl benzoate (HHB), (b) the lack of expression of several Coq proteins in COQ null mutants, and (c) the restoration of CoQ biosynthesis complex after COQ8 overexpression. The model we propose based on the formation of a multiprotein complex should facilitate a better understanding of CoQ biosynthesis. According to this model, the complex assembly requires the synthesis of a precursor such as HHB by Coq2p that must be recognized by the regulatory protein Coq4p to act as the core component of the complex. The phosphorylation of Coq3p and Coq5p by the kinase Coq8p facilitates the formation of an initial precomplex of 700 kDa that contains all Coq proteins with the exception of Coq7p. The precomplex is required for the synthesis of 5-demethoxy-Q6 , the substrate of Coq7p. When cells require de novo CoQ6 synthesis, Coq7p is dephosphorylated by Ptc7p, a mitochondrial phosphatase that activates the synthesis of CoQ6. This event allows for the full assembly of a complex of 1,300 kDa that is responsible for the final product of the pathway, CoQ6 .

  1. 49 CFR 376.22 - Exemption for private carrier leasing and leasing between authorized carriers.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Exemption for private carrier leasing and leasing... MOTOR CARRIER SAFETY REGULATIONS LEASE AND INTERCHANGE OF VEHICLES Exemptions for the Leasing Regulations § 376.22 Exemption for private carrier leasing and leasing between authorized carriers....

  2. Exemption values and measurements in international comparison

    International Nuclear Information System (INIS)

    Activities are developed worldwide to systematically derive exemption limits or exemption values (IAEA, ICRP, Radiation Protection Ordinance) for different applications according to uniform principles. An important step in this regard is the adoption of the new guideline of the EU Council on radiation protection. Also regarding a uniform definition of the exemption of material from nuclear installations, agreement should be reached soon in Europe. Due to different concepts of ultimate disposal of radioactive wastes, in particular low level wastes, internationally there is no prospect of a uniform regulation concerning the exemption of very low level wastes, while in Germany a corresponding recommendation has already been made by the radiation protection commission. The exemption limits valid at present are mentioned. (orig./HP)

  3. 75 FR 25917 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-05-10

    ..., 2000 (65 FR 19476). This information is also available at http://www.regulations.gov . FOR FURTHER... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  4. Creating functional sophistication from simple protein building blocks, exemplified by factor H and the regulators of complement activation.

    Science.gov (United States)

    Makou, Elisavet; Herbert, Andrew P; Barlow, Paul N

    2015-10-01

    Complement control protein modules (CCPs) occur in numerous functionally diverse extracellular proteins. Also known as short consensus repeats (SCRs) or sushi domains each CCP contains approximately 60 amino acid residues, including four consensus cysteines participating in two disulfide bonds. Varying in length and sequence, CCPs adopt a β-sandwich type fold and have an overall prolate spheroidal shape with N- and C-termini lying close to opposite poles of the long axis. CCP-containing proteins are important as cytokine receptors and in neurotransmission, cell adhesion, blood clotting, extracellular matrix formation, haemoglobin metabolism and development, but CCPs are particularly well represented in the vertebrate complement system. For example, factor H (FH), a key soluble regulator of the alternative pathway of complement activation, is made up entirely from a chain of 20 CCPs joined by short linkers. Collectively, therefore, the 20 CCPs of FH must mediate all its functional capabilities. This is achieved via collaboration and division of labour among these modules. Structural studies have illuminated the dynamic architectures that allow FH and other CCP-rich proteins to perform their biological functions. These are largely the products of a highly varied set of intramolecular interactions between CCPs. The CCP can act as building block, spacer, highly versatile recognition site or dimerization mediator. Tandem CCPs may form composite binding sites or contribute to flexible, rigid or conformationally 'switchable' segments of the parent proteins. PMID:26517887

  5. 78 FR 18410 - Order Granting a Limited Exemption From Rule 102 of Regulation M Concerning the NASDAQ Stock...

    Science.gov (United States)

    2013-03-26

    ... market maker incentive programs''). \\38\\ Letter from Gus Sauter, Managing Director and Chief Investment... the MQP.\\24\\ One commenter stated that the MQP program ``could create value for an issuer,'' ``jump... Market LLC Market Quality Program Pilot Pursuant to Regulation M Rule 102(e) March 20, 2013....

  6. Should Religious Groups Be Exempt from Civil Rights Laws?

    OpenAIRE

    Minow, Martha Louise

    2007-01-01

    Should a private, religious university lose its tax-exempt status because it bans interracial dating? Should a religious school fire a pregnant married teacher on religious grounds despite the ban against gender discrimination in employment? Should a religious social service agency be exempt from a state regulation banning discrimination in the delivery of social services on the basis of sexual orientation? This Article argues that courts and legislatures have granted and refused exemptions f...

  7. The trp RNA-binding attenuation protein of Bacillus subtilis regulates translation of the tryptophan transport gene trpP (yhaG) by blocking ribosome binding.

    Science.gov (United States)

    Yakhnin, Helen; Zhang, Hong; Yakhnin, Alexander V; Babitzke, Paul

    2004-01-01

    Expression of the Bacillus subtilis tryptophan biosynthetic genes (trpEDCFBA and pabA [trpG]) is regulated in response to tryptophan by TRAP, the trp RNA-binding attenuation protein. TRAP-mediated regulation of the tryptophan biosynthetic genes includes a transcription attenuation and two distinct translation control mechanisms. TRAP also regulates translation of trpP (yhaG), a single-gene operon that encodes a putative tryptophan transporter. Its translation initiation region contains triplet repeats typical of TRAP-regulated mRNAs. We found that regulation of trpP and pabA is unaltered in a rho mutant strain. Results from filter binding and gel mobility shift assays demonstrated that TRAP binds specifically to a segment of the trpP transcript that includes the untranslated leader and translation initiation region. While the affinities of TRAP for the trpP and pabA transcripts are similar, TRAP-mediated translation control of trpP is much more extensive than for pabA. RNA footprinting revealed that the trpP TRAP binding site consists of nine triplet repeats (five GAG, three UAG, and one AAG) that surround and overlap the trpP Shine-Dalgarno (S-D) sequence and translation start codon. Results from toeprint and RNA-directed cell-free translation experiments indicated that tryptophan-activated TRAP inhibits TrpP synthesis by preventing binding of a 30S ribosomal subunit. Taken together, our results establish that TRAP regulates translation of trpP by blocking ribosome binding. Thus, TRAP coordinately regulates tryptophan synthesis and transport by three distinct mechanisms: attenuation transcription of the trpEDCFBA operon, promoting formation of the trpE S-D blocking hairpin, and blocking ribosome binding to the pabA and trpP transcripts. PMID:14702295

  8. 49 CFR 525.11 - Termination of exemption; amendment of alternative average fuel economy standard.

    Science.gov (United States)

    2010-10-01

    ... average fuel economy standard. 525.11 Section 525.11 Transportation Other Regulations Relating to... EXEMPTIONS FROM AVERAGE FUEL ECONOMY STANDARDS § 525.11 Termination of exemption; amendment of alternative average fuel economy standard. (a) Any exemption granted under this part for an affected model year...

  9. 78 FR 56841 - Arbitrage Rebate Overpayments on Tax-Exempt Bonds

    Science.gov (United States)

    2013-09-16

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BK80 Arbitrage Rebate Overpayments on Tax-Exempt Bonds... recovery of overpayments of arbitrage rebate on tax- exempt bonds and other tax-advantaged bonds. These... certain other rules. These proposed regulations affect issuers of tax-exempt and tax-advantaged...

  10. 76 FR 13932 - Disclosure of Information to State Officials Regarding Tax-Exempt Organizations

    Science.gov (United States)

    2011-03-15

    ... Regarding Tax-Exempt Organizations AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice of... denials and revocations of tax-exempt status) for the purpose of administering state laws governing certain tax-exempt organizations and their activities. These regulations will affect such...

  11. CsrA Regulates Translation of the Escherichia coli Carbon Starvation Gene, cstA, by Blocking Ribosome Access to the cstA Transcript

    OpenAIRE

    Ashok K Dubey; Baker, Carol S.; Suzuki, Kazushi; Jones, A. Daniel; Pandit, Pallavi; Romeo, Tony; Babitzke, Paul

    2003-01-01

    CsrA is a global regulator that binds to two sites in the glgCAP leader transcript, thereby blocking ribosome access to the glgC Shine-Dalgarno sequence. The upstream CsrA binding site (GCACACGGAU) was used to search the Escherichia coli genomic sequence for other genes that might be regulated by CsrA. cstA contained an exact match that overlapped its Shine-Dalgarno sequence. cstA was previously shown to be induced by carbon starvation and to encode a peptide transporter. Expression of a cstA...

  12. 17 CFR 250.6 - Termination of exemptions.

    Science.gov (United States)

    2010-04-01

    ... order granting such an exemption pursuant to any applicable section of the act, and without prejudice to...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General... section now or hereafter in force pursuant to section 3(a) of the Act exempting any class of...

  13. 48 CFR 252.229-7003 - Tax Exemptions (Italy).

    Science.gov (United States)

    2010-10-01

    ... contract number. (ii) The IVA tax exemption claimed pursuant to Article 72 of Decree Law 633, dated October... this transaction is not subject to the tax in accordance with Article 72 of Decree Law 633, dated... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Tax Exemptions...

  14. 7 CFR 989.72 - Exemption of educational institutions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exemption of educational institutions. 989.72 Section... educational institutions. The committee may exempt, wholly or in part, from the volume regulation provisions... or institutions incidental to or in connection with teaching, experimental, or research...

  15. 10 CFR 71.13 - Exemption of physicians.

    Science.gov (United States)

    2010-01-01

    ... 10 CFR part 35 or the equivalent Agreement State regulations. ... NUCLEAR REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Exemptions... medicine is exempt from § 71.5 with respect to transport by the physician of licensed material for use...

  16. 29 CFR 779.356 - Application of exemptions to employees.

    Science.gov (United States)

    2010-07-01

    ...-exempt operations. For example, office workers may keep records of both the retail sales and construction....356 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... establishment under section 13(a)(4), as explained in § 779.354, the exemption from the minimum wage...

  17. 76 FR 17481 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-03-29

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  18. 75 FR 39725 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-07-12

    ... Register published on April 11, 2000 (65 FR 19476). This information is also available at http://www... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  19. 75 FR 65057 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-10-21

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  20. 76 FR 67248 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-10-31

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  1. 77 FR 64839 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-10-23

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  2. 75 FR 69737 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-11-15

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  3. 77 FR 36336 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-06-18

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  4. 77 FR 46793 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-08-06

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  5. 78 FR 64274 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-10-28

    ... System (FDMS) published in the Federal Register on January 17, 2008 (73 FR 3316). FOR FURTHER INFORMATION... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  6. 76 FR 29022 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-05-19

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  7. 76 FR 25764 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-05-05

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  8. 76 FR 70213 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-11-10

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  9. 76 FR 25766 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-05-05

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  10. 77 FR 3552 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-01-24

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If...

  11. 76 FR 1493 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-01-10

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted,...

  12. 77 FR 5874 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-02-06

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If...

  13. 32 CFR 1624.7 - Expiration of deferment or exemption.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Expiration of deferment or exemption. 1624.7 Section 1624.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM INDUCTIONS § 1624.7 Expiration of deferment or exemption. The Director shall issue an Order to Report...

  14. 77 FR 539 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-01-05

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If...

  15. Public inspection of exempt organization returns--Internal Revenue Service. Notice of proposed rulemaking.

    Science.gov (United States)

    1983-03-01

    This document contains proposed regulations relating to the public inspection of returns of certain tax exempt organizations. The regulations clarify the rules relating to the disclosure of certain information of exempt organizations. Additionally, the regulations reflect changes made by Pub. L. 96-603 and Pub. L. 95-488. PMID:10259814

  16. Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Dong, E-mail: austhudong@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Wu, Jing, E-mail: wujing8008@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Wang, Wan; Mu, Min; Zhao, Runpeng; Xu, Xuewei; Chen, Zhaoquan [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Xiao, Jian [School of Pharmacy, Wenzhou Medical College, Wenzhou (China); Hu, Fengyu; Yang, Yabo [Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou (China); Zhang, Rongbo, E-mail: lory456@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China)

    2015-05-29

    The mechanism underlying autophagy alteration by mycobacterium tuberculosis remains unclear. Our previous study shows LpqH, a lipoprotein of mycobacterium tuberculosis, can cause autophagosomes accumulation in murine macrophages. It is well known that SapM, another virulence factor, plays an important role in blocking phagosome-endosome fusion. However, the mechanism that SapM interferes with autophagy remains poorly defined. In this study, we report that SapM suppresses the autophagy flux by blocking autophagosome fusion with lysosome. Exposure to SapM results in accumulations of autophagosomes and decreased co-localization of autophagosome with lysosome. Molecularly, Rab7, a small GTPase, is blocked by SapM through its CT domain and is prevented from involvement of autophagosome-lysosome fusion. In conclusion, our study reveals that SapM takes Rab7 as a previously unknown target to govern a distinct molecular mechanism underlying autophagosome-lysosome fusion, which may bring light to a new thought about developing potential drugs or vaccines against tuberculosis. - Highlights: • A mechanism for disrupting autophagosome-lysosome fusion induced by SapM. • Rab7 is involved in SapM-inhibited autophagy. • SapM interacts with Rab7 by CT-domain. • CT-domain is indispensable to SapM-inhibited autophagy.

  17. Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7

    International Nuclear Information System (INIS)

    The mechanism underlying autophagy alteration by mycobacterium tuberculosis remains unclear. Our previous study shows LpqH, a lipoprotein of mycobacterium tuberculosis, can cause autophagosomes accumulation in murine macrophages. It is well known that SapM, another virulence factor, plays an important role in blocking phagosome-endosome fusion. However, the mechanism that SapM interferes with autophagy remains poorly defined. In this study, we report that SapM suppresses the autophagy flux by blocking autophagosome fusion with lysosome. Exposure to SapM results in accumulations of autophagosomes and decreased co-localization of autophagosome with lysosome. Molecularly, Rab7, a small GTPase, is blocked by SapM through its CT domain and is prevented from involvement of autophagosome-lysosome fusion. In conclusion, our study reveals that SapM takes Rab7 as a previously unknown target to govern a distinct molecular mechanism underlying autophagosome-lysosome fusion, which may bring light to a new thought about developing potential drugs or vaccines against tuberculosis. - Highlights: • A mechanism for disrupting autophagosome-lysosome fusion induced by SapM. • Rab7 is involved in SapM-inhibited autophagy. • SapM interacts with Rab7 by CT-domain. • CT-domain is indispensable to SapM-inhibited autophagy

  18. 7 CFR 900.700 - Exemption from assessments.

    Science.gov (United States)

    2010-01-01

    ... term “marketing promotion” means marketing research and development projects, and marketing promotion... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... eligible to obtain an assessment exemption for marketing promotion, and procedures for applying for...

  19. 48 CFR 9904.403-62 - Exemption. [Reserved

    Science.gov (United States)

    2010-10-01

    ... Section 9904.403-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.403-62 Exemption....

  20. Experience in the application of exemption principles. Proceedings of a specialists meeting held in Vienna, 2-4 November 1993

    International Nuclear Information System (INIS)

    The Proceedings presentations have been grouped in 4 Sessions: International developments on principles and standards (3 papers), Exemption principles in national regulations (8 papers), Derived exemption and clearance levels (6 papers) and Practical application of exemption and clearance concepts (5 papers). A separate abstract was prepared for each paper. Refs, figs and tabs

  1. The politics and strategy of industry self-regulation: the pharmaceutical industry's principles for ethical direct-to-consumer advertising as a deceptive blocking strategy.

    Science.gov (United States)

    Arnold, Denis G; Oakley, James L

    2013-06-01

    As the pharmaceutical industry lobbies European regulators to permit direct-to-consumer advertising (DTCA) of prescription drugs in the European Union, we found that five leading companies violated industry-developed and -promulgated standards for ethical advertising in the United States. Utilizing multiple data sources and methods, we demonstrate a consistent failure by companies that market erectile dysfunction drugs to comply with the industry's guiding principles for ethical DTCA over a four-year period despite pledges of compliance by company leaders. Noncompliance resulted in children being exposed to sexually themed promotional messages more than 100 billion times. We argue that the guidelines are a coordinated effort by the industry to prevent unwanted federal regulation, and we introduce the concept of a blocking strategy to explain company behavior and to advance theoretical understanding of firms' public affairs strategies. We recommend policy responses to prevent deceptive practices, protect children from adult content, and promote genuine health care education. PMID:23418365

  2. 16 CFR Appendix to Part 460 - Exemptions

    Science.gov (United States)

    2010-01-01

    ... Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES LABELING AND ADVERTISING OF HOME INSULATION Pt... the unfair or deceptive acts or practices to which the rule relates. In response to petitions from industry representatives, the Commission has granted exemptions from specific requirements of 16 CFR...

  3. 7 CFR 982.57 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exemptions. 982.57 Section 982.57 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... as do not interfere with the volume and quality control objectives of this part, and shall...

  4. 43 CFR 2.79 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... regulations in this subpart implementing these paragraphs: (1) Investigative Case File System, Interior/FWS-20... Files System, Interior/Office of the Solicitor-1 to the extent that it consists of investigatory... to 5 U.S.C 552a(j)(2) the following systems of records have been exempted from all of the...

  5. 48 CFR 9904.402-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.402-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.402-62 Exemption. None for this Standard....

  6. 48 CFR 9904.401-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.401-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.401-62 Exemption. None for this Standard....

  7. 48 CFR 9904.404-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.404-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.404-62 Exemption. None for this Standard....

  8. 48 CFR 9904.405-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.405-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.405-62 Exemption. None for this Standard....

  9. Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene.

    OpenAIRE

    McClinton, D; Stafford, J; Brents, L; Bender, T. P.; Kuehl, W M

    1990-01-01

    During chemically induced differentiation of Friend virus-infected mouse erythroleukemia (MEL) cell lines, there is a biphasic down-regulation of the c-myb proto-oncogene. A plasmid containing a murine c-myb cDNA controlled by a mouse metallothionein I promoter was transfected into the C19 MEL cell line. For six transfected clones, it was found that expression of the exogenous c-myb mRNA could be up-regulated by the addition of 120 microM ZnCl2 and that the N,N'-hexamethylenebisacetamide-indu...

  10. Effector-triggered immunity blocks pathogen degradation of an immunity-associated vesicle traffic regulator in Arabidopsis.

    Science.gov (United States)

    Nomura, Kinya; Mecey, Christy; Lee, Young-Nam; Imboden, Lori Alice; Chang, Jeff H; He, Sheng Yang

    2011-06-28

    Innate immunity in plants can be triggered by microbe- and pathogen-associated molecular patterns. The pathogen-associated molecular pattern-triggered immunity (PTI) is often suppressed by pathogen effectors delivered into the host cell. Plants can overcome pathogen suppression of PTI and reestablish pathogen resistance through effector-triggered immunity (ETI). An unanswered question is how plants might overcome pathogen-suppression of PTI during ETI. Findings described in this paper suggest a possible mechanism. During Pseudomonas syringae pathovar tomato (Pst) DC3000 infection of Arabidopsis, a host ADP ribosylation factor guanine nucleotide exchange factor, AtMIN7, is destabilized by the pathogen effector HopM1 through the host 26S proteasome. In this study, we discovered that AtMIN7 is required for not only PTI, consistent with the notion that Pst DC3000 degrades AtMIN7 to suppress PTI, but also ETI. The AtMIN7 level in healthy plants is low, but increases posttranscriptionally in response to activation of PTI. Whereas DC3000 infection led to degradation of AtMIN7, activation of ETI by three different effectors, AvrRpt2, AvrPphB, and HopA1, in Col-0 plants blocks the ability of Pst DC3000 to destabilize AtMIN7. Further analyses of bacterial translocation of HopM1 and AtMIN7 stability in HopM1 transgenic plants show that ETI prevents HopM1-mediated degradation of AtMIN7 inside the plant cell. Both AtMIN7 and HopM1 are localized to the trans-Golgi network/early endosome, a subcellular compartment that is not previously known to be associated with bacterial pathogenesis in plants. Thus, blocking pathogen degradation of trans-Golgi network/early endosome-associated AtMIN7 is a critical part of the ETI mechanism to counter bacterial suppression of PTI.

  11. Heart Block

    Science.gov (United States)

    ... the signal causes the heart to contract and pump blood. Heart block occurs if the electrical signal is ... degree heart block limits the heart's ability to pump blood to the rest of the body. This type ...

  12. Population Blocks.

    Science.gov (United States)

    Smith, Martin H.

    1992-01-01

    Describes an educational game called "Population Blocks" that is designed to illustrate the concept of exponential growth of the human population and some potential effects of overpopulation. The game material consists of wooden blocks; 18 blocks are painted green (representing land), 7 are painted blue (representing water); and the remaining…

  13. 15 CFR 30.35 - Procedure for shipments exempt from filing requirements.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Procedure for shipments exempt from filing requirements. 30.35 Section 30.35 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From...

  14. Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression.

    Directory of Open Access Journals (Sweden)

    Alessio Ligabue

    Full Text Available BACKGROUND: 5-fluorouracil, a commonly used chemotherapeutic agent, up-regulates expression of human thymidylate synthase (hTS. Several different regulatory mechanisms have been proposed to mediate this up-regulation in distinct cell lines, but their specific contributions in a single cell line have not been investigated to date. We have established the relative contributions of these previously proposed regulatory mechanisms in the ovarian cancer cell line 2008 and the corresponding cisplatin-resistant and 5-FU cross-resistant-subline C13*. METHODOLOGY/PRINCIPAL FINDINGS: Using RNA polymerase II inhibitor DRB treated cell cultures, we showed that 70-80% of up-regulation of hTS results from transcriptional activation of TYMS mRNA. Moreover, we report that 5-FU compromises the cell cycle by blocking the 2008 and C13* cell lines in the S phase. As previous work has established that TYMS mRNA is synthesized in the S and G(1 phase and hTS is localized in the nuclei during S and G(2-M phase, the observed cell cycle changes are also expected to affect the intracellular regulation of hTS. Our data also suggest that the inhibition of the catalytic activity of hTS and the up-regulation of the hTS protein level are not causally linked, as the inactivated ternary complex, formed by hTS, deoxyuridine monophosphate and methylenetetrahydrofolate, was detected already 3 hours after 5-FU exposure, whereas substantial increase in global TS levels was detected only after 24 hours. CONCLUSIONS/SIGNIFICANCE: Altogether, our data indicate that constitutive TYMS mRNA transcription, cell cycle-induced hTS regulation and hTS enzyme stability are the three key mechanisms responsible for 5-fluorouracil induced up-regulation of human thymidylate synthase expression in the two ovarian cancer cell lines studied. As these three independent regulatory phenomena occur in a precise order, our work provides a feasible rationale for earlier observed synergistic combinations of 5

  15. The coming changes in tax-exempt health care finance.

    Science.gov (United States)

    Carlile, L L; Serchuk, B M

    1995-01-01

    On December 30, 1994, the Internal Revenue Service (IRS) published proposed regulations (Proposed Regulations) that if enacted would significantly change the climate and rules of federal income tax law controlling the issuance and maintenance of tax-exempt bonds for governmental and 501(c)(3) health care borrowers. This article (1) summarizes the aspects of the Proposed Regulations dealing with private activity tests, management contracts, allocation and accounting rules, change in use of financed facilities, and antiabuse rules, and (2) summarizes the possible interrelationship of the IRS's audit program for tax-exempt bonds and the Proposed Regulations. The article reviews features of the Proposed Regulations that will affect either the costs or administrative burdens of managing the federal tax compliance of future tax-exempt health care borrowings. PMID:8528823

  16. Should Religious Groups Ever Be Exempt From Civil Rights Laws?

    OpenAIRE

    Minow, Martha Louise

    2007-01-01

    Should a private religious university lose its tax exempt status if it bans interracial dating? Should a religious school be able fire a pregnant married teacher because her continued work would violate the church's view that mothers of young children should not work outside the home? Should a religious social service agency, such as Catholic Charities, be exempt from a state regulation banning discrimination in the delivery of social services on the basis of sexual orientation? Should religi...

  17. The FDA Food Safety and Modernization Act and the Exemption for Small Firms

    OpenAIRE

    Pouliot, Sebastien

    2011-01-01

    The FDA Food Safety Modernization Act of 2010 is new legislation that mandates, among other things, new food safety standards. The act includes a clause that exempts small firms from new regulatory requirements. This paper investigates the effects of a small firm exemption from more stringent food safety standards. The model compares food safety, total output and the number of market participants for different food safety regulation with and without an exemption for small firms. The numerical...

  18. Zitongxi Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ Zitongxi Block (Western Zitong Block), is located in Zitong County, northwest of Sichuan Province (as shown on Fig. 8 ). Geologically. it is situated in the Zitong Depression, southwest of the middle Longmenshan faulted and folded belt, covering an area of 1 830 km2. Transportation is very convenient. A crisscross network of highways run through the block and the Baocheng railway is nearby. The climate is moderate. Most area belongs to hilly land with the elevation of 500-600 m.The Tongjiang River runs across the area.

  19. 29 CFR 801.11 - Exemption for national defense and security.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exemption for national defense and security. 801.11 Section 801.11 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS APPLICATION OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Exemptions § 801.11...

  20. 29 CFR 780.405 - Exemption is direct and does not mean activities are agriculture.

    Science.gov (United States)

    2010-07-01

    ... agriculture. 780.405 Section 780.405 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture or Irrigation That Is Exempted From the Overtime...

  1. 75 FR 38147 - FirstEnergy Nuclear Operating Company; Davis-Besse Nuclear Power Station; Exemption

    Science.gov (United States)

    2010-07-01

    ... COMMISSION FirstEnergy Nuclear Operating Company; Davis-Besse Nuclear Power Station; Exemption 1.0 Background... No. NFP-3, which authorizes operation of the Davis-Besse Nuclear Power Station, Unit 1 (DBNPS). The... regulations. Therefore, the exemption is authorized by law. Davis-Besse Nuclear Power Station...

  2. 29 CFR 780.711 - Exemption of mixed business applies only to country elevators.

    Science.gov (United States)

    2010-07-01

    ... elevators. 780.711 Section 780.711 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... FAIR LABOR STANDARDS ACT Employment by Small Country Elevators Within Area of Production; Exemption... Elevator § 780.711 Exemption of mixed business applies only to country elevators. The language of...

  3. 10 CFR 9.19 - Segregation of exempt information and deletion of identifying details.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Segregation of exempt information and deletion of identifying details. 9.19 Section 9.19 Energy NUCLEAR REGULATORY COMMISSION PUBLIC RECORDS Freedom of Information Act Regulations § 9.19 Segregation of exempt information and deletion of identifying details....

  4. 7 CFR 3565.6 - Inclusion of tax-exempt debt.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Inclusion of tax-exempt debt. 3565.6 Section 3565.6 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM General Provisions § 3565.6 Inclusion of tax-exempt...

  5. 16 CFR 1702.16 - Petitions requesting an exemption for a drug or a new drug.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Petitions requesting an exemption for a drug or a new drug. 1702.16 Section 1702.16 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION POISON PREVENTION PACKAGING ACT OF 1970 REGULATIONS PETITIONS FOR EXEMPTIONS FROM POISON PREVENTION PACKAGING ACT REQUIREMENTS; PETITION PROCEDURES...

  6. 17 CFR 250.49 - Certain exemptions granted to non-utility subsidiaries.

    Science.gov (United States)

    2010-04-01

    ... than an associate or an affiliate of the acquiring company or an affiliate of an associate company, of... EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935...-utility subsidiaries. (a) Companies exempted. The exemptions provided by this section shall apply to...

  7. 77 FR 36406 - Exemption From Transportation Worker Identification Credential (TWIC) Expiration Provisions for...

    Science.gov (United States)

    2012-06-19

    ... the Maritime Sector Final Rule, 72 FR 3492 (January 25, 2007). TSA is issuing this exemption to give... Identification Credential (TWIC) Expiration Provisions for Certain Individuals Who Hold a Valid TWIC AGENCY... Administration (TSA) is granting a temporary exemption from certain TWIC regulations regarding card...

  8. 17 CFR 232.201 - Temporary hardship exemption.

    Science.gov (United States)

    2010-04-01

    ... no later than one business day after the date on which the filing was to be made. (1) An electronic... submitted to the Commission within six business days of filing the paper format document. The electronic... REGULATION S-T-GENERAL RULES AND REGULATIONS FOR ELECTRONIC FILINGS Hardship Exemptions § 232.201...

  9. 75 FR 14656 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-03-26

    ... on April 11, 2000 (65 FR 19476). This information is also available at http://www.regulations.gov...; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications... individuals for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations....

  10. Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway.

    Science.gov (United States)

    Bhui, Kulpreet; Prasad, Sahdeo; George, Jasmine; Shukla, Yogeshwer

    2009-09-18

    Chemoprevention impels the pursuit for either single targeted or cocktail of multi-targeted agents. Bromelain, potential agent in this regard, is a pharmacologically active compound, present in stems and fruits of pineapple (Ananas cosmosus), endowed with anti-inflammatory, anti-invasive and anti-metastatic properties. Herein, we report the anti tumor-initiating effects of bromelain in 2-stage mouse skin tumorigenesis model. Pre-treatment of bromelain resulted in reduction in cumulative number of tumors (CNT) and average number of tumors per mouse. Preventive effect was also comprehended in terms of reduction in tumor volume up to a tune of approximately 65%. Components of the cell signaling pathways, connecting proteins involved in cell death were targeted. Bromelain treatment resulted in upregulation of p53 and Bax and subsequent activation of caspase 3 and caspase 9 with concomitant decrease in Bcl-2. A marked inhibition in cyclooxygenase-2 (Cox-2) expression and inactivation of nuclear factor-kappa B (NF-kappaB) was recorded, as phosphorylation and consequent degradation of I kappa B alpha was blocked by bromelain. Also, bromelain treatment curtailed extracellular signal regulated protein kinase (ERK1/2), p38 mitogen-activated protein kinase (MAPK) and Akt activity. The basis of anti tumor-initiating activity of bromelain was revealed by its time dependent reduction in DNA nick formation and increase in percentage prevention. Thus, modulation of inappropriate cell signaling cascades driven by bromelain is a coherent approach in achieving chemoprevention.

  11. Ghost Block

    OpenAIRE

    Webb, Neil

    2011-01-01

    Filmed on the English south coast 'Ghost Block' depicts the uncanny and eerie atmosphere at the site of a WW2 coastal defence line. The concrete cubes were used as an anti-invasion blockade against potential landing forces. This protection line now slowly decaying and becoming enmeshed into the environment still acts as a defence to repel unwanted visitors. The area is a natural reserve to nesting birds that often lay eggs directly onto the beach surface. The blocks act as a final barrier ...

  12. Study on Economic Regulation of Collaborative Strategies among Container Shipping Companies Following Repeal of European Union Regulation 4056/86

    Directory of Open Access Journals (Sweden)

    Rawindaran Nair

    2016-06-01

    Full Text Available The European Union removed the block exemption granted under Regulation 4056/86, to liner shipping companies to provide scheduled services on a collaborative basis effective October 2008. This has also been followed by the proposed P3 alliance with participation of Maersk, MSC and CMA CGM. This paper explores, the arguments adopted by the US Federal Maritime Commission, the European Commission and the Ministry of Commerce of China, in rejecting the case proposed by the P3 alliance. The findings of this paper will inform on understanding strategies adopted by major Competition Regulatory authorities in their interpretation of horizontal collaboration in the industry.

  13. Epidural block

    Science.gov (United States)

    ... Drugs & Supplements Videos & Tools Español You Are Here: Home ... It numbs or causes a loss of feeling in the lower half your body. This lessens the pain of contractions during childbirth. An epidural block may also be used to ...

  14. Huhe Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ Huhe Block is located in the mid-west part of Inner Mogolia Autonomous Region, covering an area of 15 079km2, in the range of 109°40'-112°00'E and 39°23()-40°40'N. Topographically. the Fengzhen hill is to the east, the Yinshan Mounts is to the north, the Hetao Plain and Ordos Plateau are respectively in its west and south.The Yellow River flows across this block. The elevation is 1 000 m in the flat area and in the range of 1 000-1 300m. in the plateau area, good for the development of agriculture and industry as well as husbandry. It belongs to inland plateau climate with annually averaged temperature of 8℃, the minimum being -12℃ in winter and the maximum 22℃ in summer.

  15. 75 FR 31421 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; Application for Exempted...

    Science.gov (United States)

    2010-06-03

    ... National Oceanic and Atmospheric Administration RIN 0648-XW53 Atlantic Coastal Fisheries Cooperative Management Act Provisions; Application for Exempted Fishing Permit; Horseshoe Crabs AGENCY: National Marine... otherwise restricted by the regulations promulgated under the Atlantic Coastal Fisheries...

  16. 78 FR 69823 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2013-11-21

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment (LOAs), and... and scientific research to exempt them from regulations (e.g., fishing seasons, prohibited...

  17. 75 FR 75458 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2010-12-03

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment (LOAs), and... and scientific research that is exempt from regulations (e.g., seasons, prohibited species,...

  18. 76 FR 72678 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2011-11-25

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment (LOAs), and... and scientific research that is exempt from regulations (e.g., seasons, prohibited species,...

  19. 29 CFR 784.137 - Relationship of exemption to exemption for “offshore” activities.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Relationship of exemption to exemption for âoffshoreâ...(a)(4) Exemption § 784.137 Relationship of exemption to exemption for “offshore” activities. The... Fleming v. Hawkeye Pearl Button Co., 113 F. 2d 52; cf. McComb v. Consolidated Fisheries, 174 F. 2d 74)....

  20. An Assessment of the Human Subjects Protection Review Process for Exempt Research.

    Science.gov (United States)

    Loe, Jonathan D; Winkelman, D Alex; Robertson, Christopher T

    2016-09-01

    Medical and public health research includes surveys, interviews, and biospecimens - techniques that do not present substantial risks to subjects. Consequently, this research is exempt from regulation under the Federal Common Rule. Nevertheless, at many institutions, exempt research is frequently subject to the same regulatory process that is required for non-exempt research, requiring the consumption of time and resources for review by Institutional Review Board members or staff. The federal government has indicated an intention to reform and centralize this system, but has not yet specified the form that it will use instead. By examining the policies of the top 50 research institutions, this article assesses institutional practices surrounding exempt research, quantifies the extent of exempt-research review requirements, documents a problem of "over-compliance," and makes recommendations for reform. PMID:27587452

  1. 29 CFR 780.319 - Basic conditions of exemption.

    Science.gov (United States)

    2010-07-01

    ... OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT... which are common to both sections 13(a)(6)(C) and 13(a)(6)(D) have already been discussed in...

  2. 77 FR 20874 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-04-06

    ... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... diabetes exemption applications from seventeen individuals and requested comments from the public (77 FR... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of...

  3. 77 FR 43417 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-24

    ... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... diabetes exemption applications from 22 individuals and requested comments from the public (77 FR 33554... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of...

  4. 77 FR 43901 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-26

    ... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... diabetes exemption applications from 23 individuals and requested comments from the public (77 FR 33551... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of...

  5. 75 FR 40751 - Castor Oil, Ethoxylated, Oleate; Tolerance Exemption

    Science.gov (United States)

    2010-07-14

    ... AGENCY 40 CFR Part 180 Castor Oil, Ethoxylated, Oleate; Tolerance Exemption AGENCY: Environmental... requirement of a tolerance for residues of castor oil, ethoxylated, oleate (CAS Reg. No. 220037-02-5) with a... residues of castor oil, ethoxylated, oleate on food or feed commodities. DATES: This regulation...

  6. 29 CFR 1612.4 - Exemptions to open meeting policy.

    Science.gov (United States)

    2010-07-01

    ...) disclose the identity of a confidential source, and, in the case of a record compiled by a criminal law... arbitration, or the initiation, conduct, or disposition by the agency of a particular case of formal agency... THE SUNSHINE ACT REGULATIONS § 1612.4 Exemptions to open meeting policy. Except in a case where...

  7. 40 CFR 80.81 - Enforcement exemptions for California gasoline.

    Science.gov (United States)

    2010-07-01

    ... gasoline. 80.81 Section 80.81 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Reformulated Gasoline § 80.81 Enforcement exemptions for California gasoline. (a)(1) The requirements of subparts D, E, F, and J of this part...

  8. 77 FR 41879 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-07-16

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http...; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications... individuals for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations....

  9. 78 FR 22598 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-04-16

    ... FR 82132), or you may visit http://www.gpo.gov/fdsys/pkg/FR-2010-12-29/pdf/2010-32876.pdf . FOR...; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications... individuals for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations....

  10. 76 FR 18824 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-04-05

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http...; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications... individuals for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations....

  11. 5 CFR 551.207 - Professional exemption criteria.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Professional exemption criteria. 551.207 Section 551.207 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY..., originality or talent in a recognized field of artistic or creative endeavor. Learned professionals,...

  12. 22 CFR 123.26 - Recordkeeping requirement for exemptions.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Recordkeeping requirement for exemptions. 123.26 Section 123.26 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS... each such export. The business record should include the following information: A description of...

  13. 75 FR 38603 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-02

    ... end of the 2-year period. The comment period ended on June 16, 2010 (75 FR 27623). Discussion of...; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice... the vision requirement in the Federal Motor Carrier Safety Regulations for 21 individuals. FMCSA...

  14. 29 CFR 516.21 - Bulk petroleum employees partially exempt from overtime pay requirements pursuant to section 7(b...

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Bulk petroleum employees partially exempt from overtime pay requirements pursuant to section 7(b)(3) of the Act. 516.21 Section 516.21 Labor Regulations Relating to Labor....21 Bulk petroleum employees partially exempt from overtime pay requirements pursuant to section...

  15. 78 FR 22347 - GPU Nuclear Inc., Three Mile Island Nuclear Power Station, Unit 2, Exemption From Certain...

    Science.gov (United States)

    2013-04-15

    ... licensee has requested exemptions from the cyber security and protection of digital assets regulations as...)(2). Cyber Security under 10 CFR 73.54 is applicable to licensees currently ``licensed to operate a... that reference cyber security or protection of digital assets are not applicable and the exemptions...

  16. 9 CFR 381.15 - Exemption from definition of “poultry product” of certain human food products containing poultry.

    Science.gov (United States)

    2010-01-01

    ... productâ of certain human food products containing poultry. 381.15 Section 381.15 Animals and Animal...; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Exemptions § 381.15 Exemption from definition of “poultry product” of certain...

  17. 17 CFR 250.12 - Exemption of certain public utility companies from the definition of subsidiary companies of...

    Science.gov (United States)

    2010-04-01

    ... utility companies from the definition of subsidiary companies of holding companies. 250.12 Section 250.12... REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General Exemptions § 250.12 Exemption of certain public utility companies from the definition of subsidiary companies of holding...

  18. 50 CFR 660.406 - Exempted fishing.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Exempted fishing. 660.406 Section 660.406... Exempted fishing. (a) NMFS may allow such exempted fishing in the fishery management area as may be... accustomed fishing grounds in the fishery management area. (b) NMFS will not allow any exempted...

  19. 50 CFR 697.22 - Exempted fishing.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Exempted fishing. 697.22 Section 697.22... § 697.22 Exempted fishing. The Regional Administrator or Director may exempt any person or vessel from the requirements of this part for the conduct of exempted fishing beneficial to the management of...

  20. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide

    NARCIS (Netherlands)

    S. Feldt (Sandra); W.W. Batenburg (Wendy); I. Mazak (Istvan); U. Maschke (Ulrike); M. Wellner (Maren); H. Kvakan (Heda); R. Dechend (Ralf); A. Fiebeler (Anette); C. Burckle (Celine); A. Contrepas (Aurelie); A.H.J. Danser (Jan); M. Bader (Michael); G. Nguyen (Genevieve); F.C. Luft (Friedrich); D. Müller (Dominik)

    2008-01-01

    textabstractThe recently cloned (pro)renin receptor [(P)RR] mediates renin-stimulated cellular effects by activating mitogen-activated protein kinases and promotes nonproteolytic prorenin activation. In vivo, (P)RR is said to be blocked with a peptide consisting of 10 amino acids from the prorenin p

  1. 76 FR 51431 - Prohibited Transaction Exemptions and Grant of Individual Exemptions

    Science.gov (United States)

    2011-08-18

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF LABOR Employee Benefits Security Administration Prohibited Transaction Exemptions and Grant of Individual Exemptions Notice of Technical Correction Prohibited Transaction Exemptions and Grant of...

  2. 48 CFR 53.301-1094A - SF 1094A, Tax Exemption Certificates Accountability Record.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 1094A, Tax Exemption Certificates Accountability Record. 53.301-1094A Section 53.301-1094A Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-1094A...

  3. 48 CFR 53.301-1094 - SF 1094, U.S. Tax Exemption Certificates.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 1094, U.S. Tax Exemption Certificates. 53.301-1094 Section 53.301-1094 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-1094 SF 1094,...

  4. CORE SATURATION BLOCKING OSCILLATOR

    Science.gov (United States)

    Spinrad, R.J.

    1961-10-17

    A blocking oscillator which relies on core saturation regulation to control the output pulse width is described. In this arrangement an external magnetic loop is provided in which a saturable portion forms the core of a feedback transformer used with the thermionic or semi-conductor active element. A first stationary magnetic loop establishes a level of flux through the saturation portion of the loop. A second adjustable magnet moves the flux level to select a saturation point giving the desired output pulse width. (AEC)

  5. The small-scale treatability study sample exemption

    International Nuclear Information System (INIS)

    In 1981, the Environmental Protection Agency (EPA) issued an interim final rule that conditionally exempted ''waste samples collected solely for the purpose of monitoring or testing to determine their characteristics or composition'' from RCRA Subtitle C hazardous waste regulations. This exemption [40 CFR 261.4(d)] apples to the transportation of samples between the generator and testing laboratory, temporary storage of samples at the laboratory prior to and following testing, and storage at a laboratory for specific purposes such as an enforcement action. However, the exclusion did not include large-scale samples used in treatability studies or other testing at pilot plants or other experimental facilities. As a result of comments received by the EPA subsequent to the issuance of the interim final rule, the EPA reopened the comment period on the interim final rule on September 18, 1987, and specifically requested comments on whether or not the sample exclusion should be expanded to include waste samples used in small-scale treatability studies. Almost all responders commented favorably on such a proposal. As a result, the EPA issued a final rule (53 FR 27290, July 19, 1988) conditionally exempting waste samples used in small-scale treatability studies from full regulation under Subtitle C of RCRA. The question of whether or not to extend the exclusion to larger scale as proposed by the Hazardous Waste Treatment Council was deferred until a later date. This information Brief summarizes the requirements of the small-scale treatability exemption

  6. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection.

    Science.gov (United States)

    Marinho, Cintia Ferreira; Azeredo, Elzinandes Leal; Torrentes-Carvalho, Amanda; Marins-Dos-Santos, Alessandro; Kubelka, Claire Fernandes; de Souza, Luiz José; Cunha, Rivaldo Venâncio; de-Oliveira-Pinto, Luzia Maria

    2014-01-01

    In dengue virus (DENV) infection, complement system (CS) activation appears to have protective and pathogenic effects. In severe dengue fever (DF), the levels of DENV non-structural-1 protein and of the products of complement activation, including C3a, C5a and SC5b-9, are higher before vascular leakage occurs, supporting the hypothesis that complement activation contributes to unfavourable outcomes. The clinical manifestations of DF range from asymptomatic to severe and even fatal. Here, we aimed to characterise CS by their receptors or activation product, in vivo in DF patients and in vitro by DENV-2 stimulation on monocytes. In comparison with healthy controls, DF patients showed lower expression of CR3 (CD11b), CR4 (CD11c) and, CD59 on monocytes. The DF patients who were high producers of SC5b-9 were also those that showed more pronounced bleeding or vascular leakage. Those findings encouraged us to investigate the role of CS in vitro, using monocytes isolated from healthy subjects. Prior blocking with CR3 alone (CD11b) or CR3 (CD11b/CD18) reduced viral infection, as quantified by the levels of intracellular viral antigen expression and soluble DENV non-structural viral protein. However, we found that CR3 alone (CD11b) or CR3 (CD11b/CD18) blocking did not influence major histocompatibility complex presentation neither active caspase-1 on monocytes, thus probably ruling out inflammasome-related mechanisms. Although it did impair the secretion of tumour necrosis factor alpha and interferon alpha. Our data provide strategies of blocking CR3 (CD11b) pathways could have implications for the treatment of viral infection by antiviral-related mechanisms.

  7. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection.

    Directory of Open Access Journals (Sweden)

    Cintia Ferreira Marinho

    Full Text Available In dengue virus (DENV infection, complement system (CS activation appears to have protective and pathogenic effects. In severe dengue fever (DF, the levels of DENV non-structural-1 protein and of the products of complement activation, including C3a, C5a and SC5b-9, are higher before vascular leakage occurs, supporting the hypothesis that complement activation contributes to unfavourable outcomes. The clinical manifestations of DF range from asymptomatic to severe and even fatal. Here, we aimed to characterise CS by their receptors or activation product, in vivo in DF patients and in vitro by DENV-2 stimulation on monocytes. In comparison with healthy controls, DF patients showed lower expression of CR3 (CD11b, CR4 (CD11c and, CD59 on monocytes. The DF patients who were high producers of SC5b-9 were also those that showed more pronounced bleeding or vascular leakage. Those findings encouraged us to investigate the role of CS in vitro, using monocytes isolated from healthy subjects. Prior blocking with CR3 alone (CD11b or CR3 (CD11b/CD18 reduced viral infection, as quantified by the levels of intracellular viral antigen expression and soluble DENV non-structural viral protein. However, we found that CR3 alone (CD11b or CR3 (CD11b/CD18 blocking did not influence major histocompatibility complex presentation neither active caspase-1 on monocytes, thus probably ruling out inflammasome-related mechanisms. Although it did impair the secretion of tumour necrosis factor alpha and interferon alpha. Our data provide strategies of blocking CR3 (CD11b pathways could have implications for the treatment of viral infection by antiviral-related mechanisms.

  8. Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors.

    Directory of Open Access Journals (Sweden)

    Xian Zhang

    Full Text Available Epithelial-mesenchymal transition (EMT is the first step required for breast cancer to initiate metastasis. However, the potential of drugs to block and reverse the EMT process are not well explored. In the present study, we investigated the inhibitory effect of beta-elemene (ELE, an active component of a natural plant-derived anti-neoplastic agent in an established EMT model mediated by transforming growth factor-beta1 (TGF-β1. We found that ELE (40 µg/ml blocked the TGF-β1-induced phenotypic transition in the human breast cancer cell line MCF-7. ELE was able to inhibit TGF-β1-mediated upregulation of mRNA and protein expression of nuclear transcription factors (SNAI1, SNAI2, TWIST and SIP1, potentially through decreasing the expression and phosphorylation of Smad3, a central protein mediating the TGF-β1 signalling pathway. These findings suggest a potential therapeutic benefit of ELE in treating basal-like breast cancer.

  9. Exemption of the use of radiation from the safety licence and reporting obligation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The primary means of controlling the use of radiation is the safety licence procedure. The safety licence, and the granting of the licence, are regulated in the section 16 of the Finnish Radiation Act (592/1991). In section 17 of the act, certain practices are exempted from the safety licence. In addition to these practices, the Radiation and Nuclear Safety (STUK) may (on the basis of the same legal clause) exempt other types of radiation use from the safety licence, if it is possible to ascertain with sufficient reliability that the use of the radiation will not cause damage or danger to health. This guide presents the conditions applying to exemption from the safety licence for the use of radiation and reporting obligation, and also the exemption values for radioactive substances which, if exceeded, will entail the application of the safety licence and notification procedure for the use of radiation in question. The guide also presents exemptions in the use of exemption values, and requirements associated with the exemption of radiation appliances. However, the guide does not apply to the use of nuclear energy.

  10. 3D PLUS HI-REL DDR2 Termination Regulator Module- A Building Block Function for High Reliability SDRAM DDR2 System Architecture

    Science.gov (United States)

    Perrot, Nicolas; Dubus, Patrick; Garcia-Sanchez, Esther

    2015-09-01

    Memory system architectures using DDR2 technology need to be compliant with JEDEC JESD8-15A standard [1]. Therefore a bus termination regulator able to sink and source current while regulating VTT voltage is used for this purpose. Such module has been developed by 3D PLUS and is the first space qualified DDR Termination Regulator (DDR2-TR) available on the market. It is based on an innovative Bang-Bang regulation principle, chosen for its speed performance and to guarantee an output voltage that remains within the predefined limits regardless of any output current transients. The output filter type is selected to make the module rugged to any overload condition without complex protection circuits. The module has been specifically designed for low input voltage, low noise and high reliability systems where space is a key consideration. The module uses the 3D PLUS SIP (System-In-Package) technology embedding 3 stacked PCBs. No external filters or decoupling capacitors are needed.

  11. Ultrasound guided supraclavicular block.

    LENUS (Irish Health Repository)

    Hanumanthaiah, Deepak

    2013-09-01

    Ultrasound guided regional anaesthesia is becoming increasingly popular. The supraclavicular block has been transformed by ultrasound guidance into a potentially safe superficial block. We reviewed the techniques of performing supraclavicular block with special focus on ultrasound guidance.

  12. Improving European Gas Infrastructure Regulation. Lessons from Theory and Practice

    International Nuclear Information System (INIS)

    As an instrument to trigger and speed up new investments in gas infrastructure across the European Union, the European Commission has implemented an exemption regime where new investment projects can apply for an exemption from default third party access regulation and tariff regulation. In this contribution we assess access holiday and transaction cost economics' literature and derive conditions for applying an exemption regime. We test whether these conditions are applied in practice by analysing the exemption application process of the Netherlands - UK interconnector (BBL). We conclude that current practice could substantially be improved.

  13. Assessing exemptions under the ballast water management convention: preclude the Trojan horse.

    Science.gov (United States)

    Olenin, Sergej; Ojaveer, Henn; Minchin, Dan; Boelens, Rick

    2016-02-15

    The International Maritime Organization (IMO) Ballast Water Management Convention (BWMC) is a powerful instrument aimed at reducing spread of harmful aquatic organisms and pathogens (HAOPs). As BWMC is expected to enter into force soon, shipping companies will start seeking exemptions for ballast water management in accordance with BWMC Regulation A-4. However, without scientifically robust risk assessment (RA) and consistent rules, the exemptions may introduce a new form of risk within a convention generally designed to reduce risks. This paper describes an adaptive system for granting exemptions, consisting of six major components: target species selection procedure, port-to-port RA, monitoring, information support, administrative decision and review process. The system is based on key principles defined in the IMO guidelines for RA and is designed to continuously accumulate evolving experience on granting exemptions. The ultimate goal is to contribute to the control of the spread of HAOPs, without placing an unnecessary burden on the shipping industry. PMID:26795122

  14. 7 CFR 922.110 - Container exemption.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container exemption. 922.110 Section 922.110... COUNTIES IN WASHINGTON Container Exemption; Waivers of Inspection and Certification § 922.110 Container exemption. Whenever container limitations are effective pursuant to § 922.52, a handler may make...

  15. 29 CFR 570.126 - Parental exemption.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Parental exemption. 570.126 Section 570.126 Labor... Provisions of the Fair Labor Standards Act of 1938, as Amended Exemptions § 570.126 Parental exemption. By... place of a parent may employ his own child or a child in his custody under the age of 16 years in...

  16. 50 CFR 660.516 - Exempted fishing.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Exempted fishing. 660.516 Section 660.516... Exempted fishing. (a) General. In the interest of developing an efficient and productive fishery for CPS, the Regional Administrator may issue exempted fishing permits (EFP) for the harvest of CPS...

  17. Are LCCEs Exempt from Income Taxes?

    OpenAIRE

    Philipsen, Nayna Campbell

    2002-01-01

    Lamaze International Certified Childbirth Educators (LCCEs) may incorporate as tax-exempt organizations under the federal tax law if they meet all of the outlined requirements. They may then be considered exempt from income taxes for the purpose of any law that refers to tax-exempt organizations.

  18. Lauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection.

    Science.gov (United States)

    Dong, Linlin; Li, Xiaolin; Huang, Li; Gao, Ying; Zhong, Lina; Zheng, Yuanyuan; Zuo, Yuanmei

    2014-01-01

    Tomato (Solanum lycopersicum) crops can be severely damaged due to parasitism by the root-knot nematode (RKN) Meloidogyne incognita, but are protected when intercropped with crown daisy (Chrysanthemum coronarium L.). Root exudate may be the determining factor for this protection. An experiment using pots linked by a tube and Petri dish experiments were undertaken to confirm that tomato-crown daisy intercropping root exudate decreased the number of nematodes and alleviated nematode damage, and to determine crown daisy root exudate-regulated nematode chemotaxis. Following a gas chromatography-mass spectrometry assay, it was found that the intercropping protection was derived from the potent bioactivity of a specific root exudate component of crown daisy, namely lauric acid. The Mi-flp-18 gene, encoding an FMRFamide-like peptide neuromodulator, regulated nematode chemotaxis and infection by RNA interference. Moreover, it was shown that lauric acid acts as both a lethal trap and a repellent for M. incognita by specifically regulating Mi-flp-18 expression in a concentration-dependent manner. Low concentrations of lauric acid (0.5-2.0mM) attract M. incognita and consequently cause death, while high concentrations (4.0mM) repel M. incognita. This study elucidates how lauric acid in crown daisy root exudate regulates nematode chemotaxis and disrupts Mi-flp-18 expression to alleviate nematode damage, and presents a general methodology for studying signalling systems affected by plant root exudates in the rhizosphere. This could lead to the development of economical and feasible strategies for controlling plant-parasitic nematodes, and provide an alternative to the use of pesticides in farming systems. PMID:24170741

  19. 76 FR 59503 - Listing of Color Additives Exempt From Certification; Reactive Blue 69; Confirmation of Effective...

    Science.gov (United States)

    2011-09-27

    ... May 4, 2011 (76 FR 25234). The final rule amended the color additive regulations to provide for the... May 4, 2011 (76 FR 25234), FDA amended the color additive regulations to add 21 CFR 73.3129 to provide... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Listing of Color Additives Exempt...

  20. 29 CFR 779.388 - Exemption provided for food or beverage service employees.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exemption provided for food or beverage service employees. 779.388 Section 779.388 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS THE FAIR LABOR STANDARDS ACT AS APPLIED...

  1. 29 CFR 780.520 - Particular operations which may be exempt.

    Science.gov (United States)

    2010-07-01

    ... 780.520 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO... includes piling the tobacco in piles or bulks of about 4,000 pounds each for the purpose of fermenting...

  2. 77 FR 55509 - Indiana Michigan Power Company; Donald C. Cook Nuclear Plant, Unit 2; Exemption

    Science.gov (United States)

    2012-09-10

    ... core cooling systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR 50, ``ECCS... regulations. As written, the regulations presume the use of zircaloy or ZIRLO TM fuel rod cladding. Thus, an... fuel rod cladding material. Accordingly, the licensee requested an exemption that would allow the...

  3. 48 CFR 719.271-7 - Reports on procurement actions that are exempted from screening.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Reports on procurement actions that are exempted from screening. 719.271-7 Section 719.271-7 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies...

  4. Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway

    Science.gov (United States)

    Liang, Yanfang; Chen, Qianqian; Du, Wenjing; Chen, Can; Li, Feifei; Yang, Jingying; Peng, Jianyu; Kang, Dongping; Lin, Bihua; Chai, Xingxing; Zhou, Keyuan; Zeng, Jincheng

    2016-01-01

    Epstein-Barr virus-induced gene 3 (EBI3) is a member of the interleukin-12 (IL-12) family structural subunit and can form a heterodimer with IL-27p28 and IL-12p35 subunit to build IL-27 and IL-35, respectively. However, IL-27 stimulates whereas IL-35 inhibits antitumor T cell responses. To date, little is known about the role of EBI3 in tumor microenvironment. In this study, firstly we assessed EBI3, IL-27p28, IL-12p35, gp130, and p-STAT3 expression with clinicopathological parameters of colorectal cancer (CRC) tissues; then we evaluated the antitumor T cell responses and tumor growth with a EBI3 blocking peptide. We found that elevated EBI3 may be associated with IL-12p35, gp130, and p-STAT3 to promote CRC progression. EBI3 blocking peptide promoted antitumor cytotoxic T lymphocyte (CTL) response by inducing Granzyme B, IFN-γ production, and p-STAT3 expression and inhibited CRC cell proliferation and tumor growth to associate with suppressing gp130 and p-STAT3 expression. Taken together, these results suggest that EBI3 may mediate a bidirectional reciprocal-regulation STAT3 signaling pathway to assist the tumor escape immune surveillance in CRC. PMID:27247488

  5. Creative Construction: Unit Blocks.

    Science.gov (United States)

    Texas Child Care, 1999

    1999-01-01

    Describes the use of unit blocks with young children in early childhood education (ECE) settings to expand all areas of the curriculum. Discusses the origin of blocks in ECE programs, presents developmental stages of block play, describes children's building styles, and makes recommendations for getting started in block play for children of…

  6. 40 CFR 166.45 - Duration of crisis exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Duration of crisis exemption. 166.45... EXEMPTION OF FEDERAL AND STATE AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Crisis Exemptions § 166.45 Duration of crisis exemption. A crisis exemption may be authorized for: (a) Only as long as...

  7. 19 CFR 148.53 - Exemption for tools of trade.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Exemption for tools of trade. 148.53 Section 148.53 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Other Exemptions § 148.53 Exemption for tools of trade. (a) Exemption....

  8. 29 CFR 793.20 - Exclusive engagement in exempt work.

    Science.gov (United States)

    2010-07-01

    ... LABOR STANDARDS ACT Workweek Application of Exemption § 793.20 Exclusive engagement in exempt work. An employee who engages exclusively in a workweek in work which is exempt under section 13(b)(9) is exempt... 29 Labor 3 2010-07-01 2010-07-01 false Exclusive engagement in exempt work. 793.20 Section...

  9. Identification of a Dynamic Core Transcriptional Network in t(8;21 AML that Regulates Differentiation Block and Self-Renewal

    Directory of Open Access Journals (Sweden)

    Anetta Ptasinska

    2014-09-01

    Full Text Available Oncogenic transcription factors such as RUNX1/ETO, which is generated by the chromosomal translocation t(8;21, subvert normal blood cell development by impairing differentiation and driving malignant self-renewal. Here, we use digital footprinting and chromatin immunoprecipitation sequencing (ChIP-seq to identify the core RUNX1/ETO-responsive transcriptional network of t(8;21 cells. We show that the transcriptional program underlying leukemic propagation is regulated by a dynamic equilibrium between RUNX1/ETO and RUNX1 complexes, which bind to identical DNA sites in a mutually exclusive fashion. Perturbation of this equilibrium in t(8;21 cells by RUNX1/ETO depletion leads to a global redistribution of transcription factor complexes within preexisting open chromatin, resulting in the formation of a transcriptional network that drives myeloid differentiation. Our work demonstrates on a genome-wide level that the extent of impaired myeloid differentiation in t(8;21 is controlled by the dynamic balance between RUNX1/ETO and RUNX1 activities through the repression of transcription factors that drive differentiation.

  10. Blocking and associability change.

    Science.gov (United States)

    Jones, Peter M; Haselgrove, Mark

    2013-07-01

    Blocking of learning about a conditioned stimulus (the "blocked" cue) occurs when it is trained alongside an additional stimulus (the "blocking" cue) that has been previously presented with the outcome. A number of theories (e.g., N. J. Mackintosh. 1975a. A Theory of Attention: Variations in the Associability of Stimuli With Reinforcement. Psychological Review, 82, 276-298; J. M. Pearce & G. Hall. 1980. A Model for Pavlovian Learning: Variation in the Effectiveness of Conditioned But Not Unconditioned Stimuli. Psychological Review, 87, 532-552) account for this attenuation in learning by proposing that attention paid to the blocked cue is restricted. In three experiments, we examined the associability of both blocked and blocking cues. In Experiment 1, rats were trained with a blocking protocol before being given a test discrimination composed of two components; one of these components required the use of the previously blocked cue as a discriminative stimulus, and the other component was soluble by using the blocking cue. To our surprise, the component that depended on the blocked cue was more readily solved than the component dependent on the blocking cue. The results of Experiments 2 and 3 suggest that this is due to the quantity of exposure that each stimulus received during initial training. Implications for theories of blocking, and more widely associative learning, are discussed. PMID:23668185

  11. Blocking and associability change.

    Science.gov (United States)

    Jones, Peter M; Haselgrove, Mark

    2013-07-01

    Blocking of learning about a conditioned stimulus (the "blocked" cue) occurs when it is trained alongside an additional stimulus (the "blocking" cue) that has been previously presented with the outcome. A number of theories (e.g., N. J. Mackintosh. 1975a. A Theory of Attention: Variations in the Associability of Stimuli With Reinforcement. Psychological Review, 82, 276-298; J. M. Pearce & G. Hall. 1980. A Model for Pavlovian Learning: Variation in the Effectiveness of Conditioned But Not Unconditioned Stimuli. Psychological Review, 87, 532-552) account for this attenuation in learning by proposing that attention paid to the blocked cue is restricted. In three experiments, we examined the associability of both blocked and blocking cues. In Experiment 1, rats were trained with a blocking protocol before being given a test discrimination composed of two components; one of these components required the use of the previously blocked cue as a discriminative stimulus, and the other component was soluble by using the blocking cue. To our surprise, the component that depended on the blocked cue was more readily solved than the component dependent on the blocking cue. The results of Experiments 2 and 3 suggest that this is due to the quantity of exposure that each stimulus received during initial training. Implications for theories of blocking, and more widely associative learning, are discussed.

  12. NORM regulations

    Energy Technology Data Exchange (ETDEWEB)

    Gray, P. [ed.

    1997-02-01

    The author reviews the question of regulation for naturally occuring radioactive material (NORM), and the factors that have made this a more prominent concern today. Past practices have been very relaxed, and have often involved very poor records, the involvment of contractors, and the disposition of contaminated equipment back into commercial service. The rationale behind the establishment of regulations is to provide worker protection, to exempt low risk materials, to aid in scrap recycling, to provide direction for remediation and to examine disposal options. The author reviews existing regulations at federal and state levels, impending legislation, and touches on the issue of site remediation and potential liabilities affecting the release of sites contaminated by NORM.

  13. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Scientific research activity, exempted...-STEVENS ACT PROVISIONS General Provisions for Domestic Fisheries § 600.745 Scientific research activity, exempted fishing, and exempted educational activity. (a) Scientific research activity. Nothing in this...

  14. 42 CFR 440.315 - Exempt individuals.

    Science.gov (United States)

    2010-10-01

    ...) MEDICAL ASSISTANCE PROGRAMS SERVICES: GENERAL PROVISIONS Benchmark Benefit and Benchmark-Equivalent... exempt from mandatory enrollment in benchmark or benchmark-equivalent coverage. (a) The individual is...

  15. Generalized Block Failure

    DEFF Research Database (Denmark)

    Jönsson, Jeppe

    2015-01-01

    Block tearing is considered in several codes as a pure block tension or a pure block shear failure mechanism. However in many situations the load acts eccentrically and involves the transfer of a substantial moment in combination with the shear force and perhaps a normal force. A literature study...... yield lines around the block leads to simple interaction formulas similar to other interaction formulas in the codes.......Block tearing is considered in several codes as a pure block tension or a pure block shear failure mechanism. However in many situations the load acts eccentrically and involves the transfer of a substantial moment in combination with the shear force and perhaps a normal force. A literature study...

  16. Blocked Randomization with Randomly Selected Block Sizes

    Directory of Open Access Journals (Sweden)

    Jimmy Efird

    2010-12-01

    Full Text Available When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes.

  17. Blocked randomization with randomly selected block sizes.

    Science.gov (United States)

    Efird, Jimmy

    2011-01-01

    When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes. PMID:21318011

  18. BLOCK H-MATRICES AND SPECTRUM OF BLOCK MATRICES

    Institute of Scientific and Technical Information of China (English)

    黄廷祝; 黎稳

    2002-01-01

    The block H-matrices are studied by the concept of G-functions, several concepts of block matrices are introduced. Equivalent characters of block H-matrices are obtained. Spectrum localizations claracterized by Gfunctions for block matrices are got.

  19. 78 FR 24738 - Ethylene Oxide; Receipt of Application for Emergency Exemption, Solicitation of Public Comment

    Science.gov (United States)

    2013-04-26

    ... exemption request from the United States Department of Agriculture (USDA) Animal and Plant Health Inspection... sterilization. This notice does not constitute a decision by EPA on the application itself. The regulations... action if you are an agricultural producer, food manufacturer, or pesticide manufacturer. The...

  20. 17 CFR 270.22e-3 - Exemption for liquidation of money market funds.

    Science.gov (United States)

    2010-04-01

    ... money market funds. 270.22e-3 Section 270.22e-3 Commodity and Securities Exchanges SECURITIES AND... for liquidation of money market funds. (a) Exemption. A registered open-end management investment company or series thereof (“fund”) that is regulated as a money market fund under § 270.2a-7 is...

  1. 75 FR 29431 - Coat Protein of Plum Pox Virus; Exemption from the Requirement of a Tolerance

    Science.gov (United States)

    2010-05-26

    ... Findings In the Federal Register of November 14, 2008 (73 FR 67512) (FRL- 8388-3), EPA issued a notice... Planning and Review (58 FR 51735, October 4, 1993). Because this final rule has been exempted from review... Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use (66 FR 28355, May...

  2. 77 FR 44151 - Titanium Dioxide; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2012-07-27

    ... AGENCY 40 CFR Part 180 Titanium Dioxide; Exemption From the Requirement of a Tolerance AGENCY... from the requirement of a tolerance for residues of titanium dioxide (CAS Reg. No. 13463-67- 7) when... permissible level for residues of titanium dioxide. DATES: This regulation is effective July 27,...

  3. 29 CFR 780.803 - Basic conditions of exemption; first part, ginning of cotton.

    Science.gov (United States)

    2010-07-01

    ... cotton. 780.803 Section 780.803 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... FAIR LABOR STANDARDS ACT Employment in Ginning of Cotton and Processing of Sugar Beets, Sugar-Beet... Section 13(b)(15) Introductory § 780.803 Basic conditions of exemption; first part, ginning of...

  4. 77 FR 58977 - Exempting In-Home Video Telehealth From Copayments

    Science.gov (United States)

    2012-09-25

    ... inpatient hospital care or outpatient medical care. Specifically, the regulation exempted in-home video telehealth care from having any required copayment. VA received no significant adverse comments concerning... FR 13195 on the same date. The direct final rule and proposed rule each provided a 30-day...

  5. 78 FR 32152 - Guar Hydroxypropyltrimethylammo-nium Chloride; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2013-05-29

    ...This regulation establishes an exemption from the requirement of a tolerance for residues of guar hydroxypropyltrimethylammonium chloride (CAS Reg. No. 71329-50-5) when used as an inert ingredient (thickener/drift reduction agent) in pesticide formulations applied to growing crops. SciReg. Inc., on behalf of Rhodia Inc., submitted a petition to EPA under the Federal Food, Drug, and Cosmetic......

  6. 75 FR 9527 - Trichoderma asperellum strain ICC 012; Exemption from the Requirement of a Tolerance

    Science.gov (United States)

    2010-03-03

    ... Findings In the Federal Register of November 12, 2008 (73 FR 66897) (FRL- 8386-8), EPA issued a notice... (58 FR 51735, October 4, 1993). Because this final rule has been exempted from review under Executive... Regulations That Significantly Affect Energy Supply, Distribution, or Use (66 FR 28355, May 22, 2001)...

  7. 75 FR 763 - Dibenzylidene Sorbitol; Exemption from the Requirement of a Tolerance

    Science.gov (United States)

    2010-01-06

    ... Findings In the Federal Register of September 4, 2009 (71 FR 45848) (FRL- 8434-4), EPA issued a notice... Planning and Review (58 FR 51735, October 4, 1993). Because this final rule has been exempted from review... Concerning Regulations That Significantly Affect Energy Supply, Distribution, or Use (66 FR 28355, May...

  8. 78 FR 13864 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2013-03-01

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... received regarding our intent to issue Exempted Fishing Permits (EFPs), Scientific Research Permits (SRPs... prohibited by the regulations contained in this part for the conduct of scientific research, the...

  9. 77 FR 6704 - Exemptions From Entry Requirements and Report of Arrival Requirements for Certain Department of...

    Science.gov (United States)

    2012-02-09

    ... transporting passengers traveling on official business of the United States. This rule proposes to expand the... proposed regulation will not impose any costs or confer any benefits to private citizens or businesses. CBP... place. This rule proposes to expand those exemptions to include additional DoD-owned or...

  10. 40 CFR 180.32 - Procedure for modifying and revoking tolerances or exemptions from tolerances.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Procedure for modifying and revoking... FOOD Procedural Regulations § 180.32 Procedure for modifying and revoking tolerances or exemptions from... modifying or revoking a tolerance for a pesticide chemical residue on raw agricultural commodities...

  11. 29 CFR 794.112 - Only independent and local enterprises qualify for exemption.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Only independent and local enterprises qualify for exemption. 794.112 Section 794.112 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... Act âindependently Owned and Controlled Local Enterpriseâ § 794.112 Only independent and...

  12. 29 CFR 4902.11 - Specific exemptions: Office of Inspector General Investigative File System.

    Science.gov (United States)

    2010-07-01

    ... Investigative File System. 4902.11 Section 4902.11 Labor Regulations Relating to Labor (Continued) PENSION... General Investigative File System. (a) Criminal Law Enforcement. (1) Exemption. Under the authority... Inspector General Investigative File System—PBGC” from the provisions of 5 U.S.C. 552a (c)(3), (c)(4),...

  13. 75 FR 47464 - Exemption to Prohibition on Circumvention of Copyright Protection Systems for Access Control...

    Science.gov (United States)

    2010-08-06

    ... Copyright Office 37 CFR Part 201 Exemption to Prohibition on Circumvention of Copyright Protection Systems for Access Control Technologies AGENCY: Copyright Office, Library of Congress. ACTION: Final Rule; correction. SUMMARY: The Copyright Office makes a nonsubstantial correction to its regulation announcing...

  14. 75 FR 13142 - Florida Power and Light Company; Turkey Point, Units 3 and 4; Exemption

    Science.gov (United States)

    2010-03-18

    ... using Framatome Advanced Nuclear Power Topical Report (TR) BAW-2308, Revisions 1A and 2A, ``Initial RT NDT of Linde 80 Weld Materials.'' This exemption addresses only those parts of the regulations (i.e...-ductility reference temperature, RT NDT(U), and its associated uncertainty, . All other requirements of...

  15. 77 FR 12202 - Public Inspection of Material Relating to Tax-Exempt Organizations

    Science.gov (United States)

    2012-02-29

    ... Register (72 FR 45394-01) on August 14, 2007. One comment was received from the public in response to the... Internal Revenue Service 26 CFR Part 301 RIN 1545-BG60 Public Inspection of Material Relating to Tax-Exempt... document contains final regulations pertaining to the public inspection of material relating to...

  16. 76 FR 68511 - STP Nuclear Operating Company; South Texas Project, Units 1 and 2; Exemption

    Science.gov (United States)

    2011-11-04

    ... systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR part 50, ``ECCS Evaluation... regulations presume the use of zircaloy or ZIRLO \\TM\\ fuel rod cladding. Thus, an exemption from the requirements of 10 CFR 50.46 and Appendix K is needed to support the use of a different fuel rod...

  17. 76 FR 55422 - Indiana Michigan Power Company; Donald C. Cook Nuclear Plant, Unit 1; Exemption

    Science.gov (United States)

    2011-09-07

    ... systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR part 50, ``ECCS Evaluation... written, the regulations presume the use of zircaloy or ZIRLO\\TM\\ fuel rod cladding. Thus, an exemption... Optimized ZIRLO\\TM\\ fuel rod cladding at CNP-1. 3.0 Discussion Pursuant to 10 CFR 50.12, the Commission...

  18. 31 CFR 585.213 - Exemption of activities related to certain international organizations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exemption of activities related to certain international organizations. 585.213 Section 585.213 Money and Finance: Treasury Regulations... related to certain international organizations. Any activities related to the United Nations...

  19. 15 CFR 30.39 - Special exemptions for shipments to the U.S. Armed Services.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Special exemptions for shipments to the U.S. Armed Services. 30.39 Section 30.39 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE...

  20. 15 CFR 30.38 - Exemption from the requirements for reporting complete commodity information.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Exemption from the requirements for reporting complete commodity information. 30.38 Section 30.38 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN...

  1. 15 CFR 30.36 - Exemption for shipments destined to Canada.

    Science.gov (United States)

    2010-01-01

    ... CFR 120-130). (4) Requiring a Department of Commerce, BIS, export license under the EAR (15 CFR 730... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Exemption for shipments destined to Canada. 30.36 Section 30.36 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign...

  2. 17 CFR 250.11 - Certain acquisitions by affiliates exempted from section 9(a)(2).

    Science.gov (United States)

    2010-04-01

    ... United States: Provided, That the acquiring company is not an affiliate under section 2(a)(11)(A) of the... AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT... section 9(a)(2). (a) Acquisitions by certain exempt holding companies. Any holding company which is...

  3. 12 CFR 218.741 - Exemption for banks effecting transactions in money market funds.

    Science.gov (United States)

    2010-01-01

    ... money market funds. 218.741 Section 218.741 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS... EXCHANGE ACT OF 1934 (REGULATION R) § 218.741 Exemption for banks effecting transactions in money market... issued by a money market fund, provided that: (1) The bank either (i) Provides the customer, directly...

  4. Lesson Thirteen Trifascicular Block

    Institute of Scientific and Technical Information of China (English)

    鲁端; 王劲

    2005-01-01

    @@ A complete trifascicular block would result in complete AV block. The idio ventricular rhythm has a slower rate and a wide QRS complex because the pacemaker is located at the peripheral part of the conduction system distal to the sites of the block1. Such a rhythm may be difficult to differentiate from bifascicular or bundle branch block combined with complete block at a higher level such as the AV node or His bundle2. Besides a slower ventricular rate, a change in the morphology of the QRS complex from a previous known bifascicular pattern would be strongly suggestive of a trifascicular origin of the complete AV block3. A His bundle recording is required for a definitive diagnosis, however.

  5. 40 CFR 166.49 - Public notice of crisis exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Public notice of crisis exemptions... PROGRAMS EXEMPTION OF FEDERAL AND STATE AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Crisis Exemptions § 166.49 Public notice of crisis exemptions. (a) Periodic notices. At least quarterly,...

  6. 29 CFR 780.406 - Exemption is from overtime only.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exemption is from overtime only. 780.406 Section 780.406...(b)(12) The Irrigation Exemption § 780.406 Exemption is from overtime only. This exemption applies only to the overtime provisions of the Act and does not affect the minimum wage, child...

  7. 28 CFR 16.84 - Exemption of Immigration Appeals System.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Immigration Appeals System... MATERIAL OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.84 Exemption of Immigration...) Decisions of the Board of Immigration Appeals (JUSTICE/BIA-001). This exemption applies only to the...

  8. 7 CFR 301.80-2b - Exempted articles. 1

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Exempted articles. 1 301.80-2b Section 301.80-2b....80-2b Exempted articles. 1 1 The articles hereby exempted remain subject to applicable restrictions under other quarantines. (a) The following articles are exempt from the certification and permit...

  9. 21 CFR 1308.34 - Exempt anabolic steroid products.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exempt anabolic steroid products. 1308.34 Section... SUBSTANCES Exempt Anabolic Steroid Products § 1308.34 Exempt anabolic steroid products. The list of compounds, mixtures, or preparations that contain an anabolic steroid that have been exempted by the...

  10. Block Advertisement Protocol

    OpenAIRE

    Nemirovsky, Danil

    2015-01-01

    Bitcoin, a decentralized cryptocurrency, has attracted a lot of attention from academia, financial service industry and enthusiasts. The trade-off between transaction confirmation throughput and centralization of hash power do not allow Bitcoin to perform at the same level as modern payment systems. Block Advertisement Protocol is proposed as a step to resolve this issue. The protocol allows block mining and block relaying to happen in parallel. The protocol dictates a miner to advertise the ...

  11. Block Cipher Analysis

    DEFF Research Database (Denmark)

    Miolane, Charlotte Vikkelsø

    ensurethat no attack violatesthe securitybounds specifiedbygeneric attack namely exhaustivekey search and table lookup attacks. This thesis contains a general introduction to cryptography with focus on block ciphers and important block cipher designs, in particular the Advanced Encryption Standard...... on small scale variants of AES. In the final part of the thesis we present a new block cipher proposal Present and examine its security against algebraic and differential cryptanalysis in particular....

  12. 40 CFR 721.45 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Exemptions. 721.45 Section 721.45 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... person has applied for and has been granted an exemption for test marketing the substance for...

  13. 20 CFR 363.4 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Exemptions. 363.4 Section 363.4 Employees' Benefits RAILROAD RETIREMENT BOARD INTERNAL ADMINISTRATION, POLICY AND PROCEDURES GARNISHMENT OF REMUNERATION OF BOARD PERSONNEL § 363.4 Exemptions. (a) The portion of any payment due to a Board...

  14. Reasons Parents Exempt Children from Receiving Immunizations

    Science.gov (United States)

    Luthy, Karlen E.; Beckstrand, Renea L.; Callister, Lynn C.; Cahoon, Spencer

    2012-01-01

    School nurses are on the front lines of educational efforts to promote childhood vaccinations. However, some parents still choose to exempt their children from receiving vaccinations for personal reasons. Studying the beliefs of parents who exempt vaccinations allows health care workers, including school nurses, to better understand parental…

  15. 32 CFR 319.13 - Specific exemptions.

    Science.gov (United States)

    2010-07-01

    ... PROGRAM DEFENSE INTELLIGENCE AGENCY PRIVACY PROGRAM § 319.13 Specific exemptions. (a) All systems of records maintained by the Director Intelligence Agency shall be exempt from the requirements of 5 U.S.C... has been properly classified. (b) The Director, Defense Intelligence Agency, designated the systems...

  16. 40 CFR 87.7 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... POLLUTION FROM AIRCRAFT AND AIRCRAFT ENGINES General Provisions § 87.7 Exemptions. (a) Exemptions based on... engines which power aircraft operated in the United States for short durations at infrequent intervals... aircraft or aircraft engines for time periods which the Secretary determines, with the concurrence of...

  17. 50 CFR 660.718 - Exempted fishing.

    Science.gov (United States)

    2010-10-01

    ... for the participating vessel in accordance with the criteria and procedures specified in 50 CFR 600... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Exempted fishing. 660.718 Section 660.718... Exempted fishing. (a) In the interest of developing an efficient and productive fishery for HMS,...

  18. 46 CFR 25.26-60 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Exemptions. 25.26-60 Section 25.26-60 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY UNINSPECTED VESSELS REQUIREMENTS Emergency Position Indicating Radio Beacons (EPIRB) § 25.26-60 Exemptions. (a) A skiff or work boat is not required to carry an...

  19. 47 CFR 15.103 - Exempted devices.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Exempted devices. 15.103 Section 15.103 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unintentional Radiators § 15.103 Exempted devices. The following devices are subject only to the general conditions of operation in §§...

  20. Medical Versus Nonmedical Immunization Exemptions for Child Care and School Attendance.

    Science.gov (United States)

    2016-09-01

    Routine childhood immunizations against infectious diseases are an integral part of our public health infrastructure. They provide direct protection to the immunized individual and indirect protection to children and adults unable to be immunized via the effect of community immunity. All 50 states, the District of Columbia, and Puerto Rico have regulations requiring proof of immunization for child care and school attendance as a public health strategy to protect children in these settings and to secondarily serve as a mechanism to promote timely immunization of children by their caregivers. Although all states and the District of Columbia have mechanisms to exempt school attendees from specific immunization requirements for medical reasons, the majority also have a heterogeneous collection of regulations and laws that allow nonmedical exemptions from childhood immunizations otherwise required for child care and school attendance. The American Academy of Pediatrics (AAP) supports regulations and laws requiring certification of immunization to attend child care and school as a sound means of providing a safe environment for attendees and employees of these settings. The AAP also supports medically indicated exemptions to specific immunizations as determined for each individual child. The AAP views nonmedical exemptions to school-required immunizations as inappropriate for individual, public health, and ethical reasons and advocates for their elimination. PMID:27573087

  1. Block Scheduling Revisited.

    Science.gov (United States)

    Queen, J. Allen

    2000-01-01

    Successful block scheduling depends on provision of initial and ongoing instructional training. Teaching strategies should vary and include cooperative learning, the case method, the socratic seminar, synectics, concept attainment, the inquiry method, and simulations. Recommendations for maximizing block scheduling are outlined. (Contains 52…

  2. Surviving Block Scheduling.

    Science.gov (United States)

    Haley, Marjorie

    A discussion of block scheduling for second language instruction looks at the advantages and disadvantages and offers some suggestions for classroom management and course organization. It is argued that block scheduling may offer a potential solution to large classes, insufficient time for labs, too little individualized instruction; few…

  3. Predictability of blocking

    International Nuclear Information System (INIS)

    Tibaldi and Molteni (1990, hereafter referred to as TM) had previously investigated operational blocking predictability by the ECMWF model and the possible relationships between model systematic error and blocking in the winter season of the Northern Hemisphere, using seven years of ECMWF operational archives of analyses and day 1 to 10 forecasts. They showed that fewer blocking episodes than in the real atmosphere were generally simulated by the model, and that this deficiency increased with increasing forecast time. As a consequence of this, a major contribution to the systematic error in the winter season was shown to derive from the inability of the model to properly forecast blocking. In this study, the analysis performed in TM for the first seven winter seasons of the ECMWF operational model is extended to the subsequent five winters, during which model development, reflecting both resolution increases and parametrisation modifications, continued unabated. In addition the objective blocking index developed by TM has been applied to the observed data to study the natural low frequency variability of blocking. The ability to simulate blocking of some climate models has also been tested

  4. Merit in Principle, Merit in Practice: An Investigation into Merit-based Human Resources Management Through the Lens of Title 5-exempt Federal Organizations

    OpenAIRE

    Woodard, Colleen A.

    2000-01-01

    This dissertation research investigates whether merit-based principles and practices are embedded into the HRM systems of 19 Title 5-exempt federal organizations. Title 5-exempt organizations, such as government corporations, serve as a vehicle for exploring the question of what constitutes merit in more loosely regulated public environments. This research fills a void in the discussion about how we can sustain a merit foundation in deregulated and decentralized federal human resources syste...

  5. Block copolymer battery separator

    Energy Technology Data Exchange (ETDEWEB)

    Wong, David; Balsara, Nitash Pervez

    2016-04-26

    The invention herein described is the use of a block copolymer/homopolymer blend for creating nanoporous materials for transport applications. Specifically, this is demonstrated by using the block copolymer poly(styrene-block-ethylene-block-styrene) (SES) and blending it with homopolymer polystyrene (PS). After blending the polymers, a film is cast, and the film is submerged in tetrahydrofuran, which removes the PS. This creates a nanoporous polymer film, whereby the holes are lined with PS. Control of morphology of the system is achieved by manipulating the amount of PS added and the relative size of the PS added. The porous nature of these films was demonstrated by measuring the ionic conductivity in a traditional battery electrolyte, 1M LiPF.sub.6 in EC/DEC (1:1 v/v) using AC impedance spectroscopy and comparing these results to commercially available battery separators.

  6. Blocking in Category Learning

    OpenAIRE

    Bott, Lewis; Hoffman, Aaron B.; Murphy, Gregory L.

    2007-01-01

    Many theories of category learning assume that learning is driven by a need to minimize classification error. When there is no classification error, therefore, learning of individual features should be negligible. We tested this hypothesis by conducting three category learning experiments adapted from an associative learning blocking paradigm. Contrary to an error-driven account of learning, participants learned a wide range of information when they learned about categories, and blocking effe...

  7. Growing Up with Their Blocks.

    Science.gov (United States)

    Winarski, Diana L.

    1995-01-01

    Describes one teacher's use of traditional wooden blocks in fifth-grade curriculum. Notes that use of blocks can teach communication, teamwork, precision, and arithmetic concepts. Also describes four easy classroom block projects. (TM)

  8. 32 CFR 310.28 - General exemption.

    Science.gov (United States)

    2010-07-01

    ... Component is not authorized to claim the exemption for records maintained by the Central Intelligence Agency... military police activities. However, where DoD offices perform multiple functions, but have...

  9. 40 CFR 92.804 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Importation of Nonconforming Locomotives and Locomotive..., and that enter the United States temporarily from Canada or Mexico are exempt from the...

  10. 32 CFR 292.6 - FOIA exemptions.

    Science.gov (United States)

    2010-07-01

    ... INFORMATION ACT PROGRAM DEFENSE INTELLIGENCE AGENCY (DIA) FREEDOM OF INFORMATION ACT § 292.6 FOIA exemptions... footnote 1 to § 292.3(a)(3). 5 Forward requests to: Defense Intelligence Agency, ATTN: DSP-1A...

  11. 29 CFR 779.347 - Exemption limited to “recognized retail establishment”; factories not exempt.

    Science.gov (United States)

    2010-07-01

    ... industry. This test limits the exemption to retail establishments only, and excludes factories as such and... 29 Labor 3 2010-07-01 2010-07-01 false Exemption limited to ârecognized retail establishmentâ... Retail or Service Establishments Engaging in Manufacturing and Processing Activities; Section...

  12. Block diagonal and schur complement preconditioners for block-toeplitz systems with small size blocks

    OpenAIRE

    Ching, WK; Ng, MK; Wen, YW

    2007-01-01

    In this paper we consider the solution of Hermitian positive definite block-Toeplitz systems with small size blocks. We propose and study block diagonal and Schur complement preconditioners for such block-Toeplitz matrices. We show that for some block-Toeplitz matrices, the spectra of the preconditioned matrices are uniformly bounded except for a fixed number of outliers where this fixed number depends only on the size of the block. Hence, conjugate gradient type methods, when applied to solv...

  13. Right bundle branch block

    DEFF Research Database (Denmark)

    Bussink, Barbara E; Holst, Anders Gaarsdal; Jespersen, Lasse;

    2013-01-01

    AimsTo determine the prevalence, predictors of newly acquired, and the prognostic value of right bundle branch block (RBBB) and incomplete RBBB (IRBBB) on a resting 12-lead electrocardiogram in men and women from the general population.Methods and resultsWe followed 18 441 participants included.......5%/2.3% in women, P Right bundle branch block was associated with significantly...... increased all-cause and cardiovascular mortality in both genders with age-adjusted hazard ratios (HR) of 1.31 [95% confidence interval (CI), 1.11-1.54] and 1.87 (95% CI, 1.48-2.36) in the gender pooled analysis with little attenuation after multiple adjustment. Right bundle branch block was associated...

  14. 78 FR 56988 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-16

    ... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating... (68 FR 52441).\\1\\ The revision must provide for individual assessment of drivers with diabetes... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  15. 78 FR 63285 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  16. 78 FR 63280 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  17. 78 FR 64267 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-28

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... diabetes mellitus, and be consistent with the criteria described in section 4018 of the Transportation... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  18. 78 FR 65034 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  19. 78 FR 63295 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  20. 78 FR 79062 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-27

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  1. 78 FR 63298 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  2. 28 CFR 36.404 - Alterations: Elevator exemption.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Alterations: Elevator exemption. 36.404... Alterations: Elevator exemption. (a) This section does not require the installation of an elevator in an... facility has an elevator....

  3. 32 CFR 322.7 - Exempt systems of records.

    Science.gov (United States)

    2010-07-01

    ... secret in the interest of national defense or foreign policy. This exemption is applicable to parts of...) System name: Health, Medical and Safety Files. (2) Exemption: (i) Investigatory material compiled...

  4. 76 FR 69793 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-11-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... Federal vision standard applicable to interstate truck and bus drivers and the reasons for the denials. FMCSA has statutory authority to exempt individuals from the vision requirement if the...

  5. 77 FR 12361 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-02-29

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... Federal vision standard applicable to interstate truck and bus drivers and the reasons for the denials. FMCSA has statutory authority to exempt individuals from the vision requirement if the...

  6. 78 FR 76394 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-12-17

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... Federal vision standard applicable to interstate truck and bus drivers and the reasons for the denials. FMCSA has statutory authority to exempt individuals from the vision requirement if the...

  7. 76 FR 25763 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-05-05

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... Federal vision standard applicable to interstate truck and bus drivers and the reasons for the denials. FMCSA has statutory authority to exempt individuals from the vision requirement if the...

  8. 75 FR 22175 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-04-27

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... Federal vision standard applicable to interstate truck and bus drivers and the reasons for the denials. FMCSA has statutory authority to exempt individuals from the vision requirement if the...

  9. 29 CFR 553.32 - Other FLSA exemptions.

    Science.gov (United States)

    2010-07-01

    ... Act provides a minimum wage and overtime pay exemption for any employee employed by an amusement or... local governments operate parks and recreational areas to which this exemption may apply. (f) Section...

  10. 29 CFR 780.3 - Exemptions discussed in this part.

    Science.gov (United States)

    2010-07-01

    ... industry are discussed in this part 780. These exemptions differ substantially in their terms, scope, and...) exemption (cotton ginning and sugar processing) discussed in subpart I of this part, and the section...

  11. Bactericidal block copolymer micelles.

    Science.gov (United States)

    Vyhnalkova, Renata; Eisenberg, Adi; van de Ven, Theo

    2011-05-12

    Block copolymer micelles with bactericidal properties were designed to deactivate pathogens such as E. coli bacteria. The micelles of PS-b-PAA and PS-b-P4VP block copolymers were loaded with biocides TCMTB or TCN up to 20 or 30 wt.-%, depending on the type of antibacterial agent. Bacteria were exposed to loaded micelles and bacterial deactivation was evaluated. The micelles loaded with TCN are bactericidal; bacteria are killed in less than two minutes of exposure. The most likely interpretation of the data is that the biocide is transferred to the bacteria by repeated micelle/bacteria contacts, and not via the solution. PMID:21275041

  12. E-Block: A Tangible Programming Tool with Graphical Blocks

    OpenAIRE

    Danli Wang; Yang Zhang; Shengyong Chen

    2013-01-01

    This paper designs a tangible programming tool, E-Block, for children aged 5 to 9 to experience the preliminary understanding of programming by building blocks. With embedded artificial intelligence, the tool defines the programming blocks with the sensors as the input and enables children to write programs to complete the tasks in the computer. The symbol on the programming block's surface is used to help children understanding the function of each block. The sequence information is transfer...

  13. 31 CFR 547.201 - Prohibited transactions involving blocked property.

    Science.gov (United States)

    2010-07-01

    ... THE CONGO SANCTIONS REGULATIONS Prohibitions § 547.201 Prohibited transactions involving blocked... pursuant to this paragraph (a); or (vii) To be owned or controlled by, or acting or purporting to act for... Specially Designated Nationals and Blocked Persons List (“SDN List”) (which is accessible via the Office...

  14. 29 CFR 2520.104-47 - Limited exemption and alternative method of compliance for filing of insurance company financial...

    Science.gov (United States)

    2010-07-01

    ... insurance company, insurance service or similar organization, provided that the administrator files a copy... filing of insurance company financial reports. 2520.104-47 Section 2520.104-47 Labor Regulations Relating... exemption and alternative method of compliance for filing of insurance company financial reports....

  15. 75 FR 6414 - Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Science.gov (United States)

    2010-02-09

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment... Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). Cardinal Growth, L.P....

  16. 78 FR 57444 - Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Science.gov (United States)

    2013-09-18

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act... Business Administration (``SBA'') Rules and Regulations. Eagle Fund III-A, L.P., provided debt and...

  17. 76 FR 77580 - Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the...

    Science.gov (United States)

    2011-12-13

    ... ADMINISTRATION Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Contemporary Healthcare... Constitute Conflicts of Interest, of the Small Business Administration (``SBA'') Rules and Regulations...

  18. 75 FR 54661 - Main Street Capital II, LP; Notice of Exemption Under Section 312 of the Small Business...

    Science.gov (United States)

    2010-09-08

    ... ADMINISTRATION Main Street Capital II, LP; Notice of Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Main Street Capital II, LP, 1300 Post Oak Blvd... Regulations (13 CFR 107.730), Financings which Constitute Conflicts of Interest. Main Street Capital II,...

  19. 78 FR 42451 - Listing of Color Additives Exempt From Certification; Reactive Blue 246 and Reactive Blue 247...

    Science.gov (United States)

    2013-07-16

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Listing of Color Additives Exempt From... color additive regulations in Sec. Sec. 73.3100 and 73.3106 (21 CFR 73.3100 and 73.3106), respectively... Blue 246), as color additives in contact lenses. We also corrected the nomenclature for Reactive...

  20. 75 FR 33666 - Parts and Accessories Necessary for Safe Operation; Applications for an Exemption From Con-Way...

    Science.gov (United States)

    2010-06-14

    ... Act Statement in the Federal Register published on April 11, 2000 (65 FR 19476) or you may visit http... Regulations (FMCSRs). On August 20, 2004, FMCSA published a final rule (69 FR 51589) implementing section 4007...; Applications for an Exemption From Con-Way Freight, TK Holdings, Inc., and Iteris, Inc. AGENCY: Federal...

  1. 78 FR 57444 - Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts...

    Science.gov (United States)

    2013-09-18

    ... (the ``Act''), in connection with the financing of a small concern, has sought an exemption under Section 312 of the Act and 13 CFR 107.730, Financings which Constitute Conflicts of Interest, of the Small Business Administration (``SBA'') Rules and Regulations. Eagle Fund III, L.P., provided debt and...

  2. 76 FR 67017 - Praesidian Capital Opportunity Fund III, LP License No. 02/02-0647; Notice Seeking Exemption...

    Science.gov (United States)

    2011-10-28

    ... financing of a small concern, has sought an exemption under Section 312 of the Act and Section 107.730, Financings which Constitute Conflicts of Interest, of the Small Business Administration Rules and Regulations (13 CFR 107.730). Praesidian Capital Opportunity Fund III, LP proposes to provide debt financing...

  3. 77 FR 11618 - Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Science.gov (United States)

    2012-02-27

    ... Act''), in connection with the financing of a small concern, has sought an exemption under Sec. 312 of the Act and Sec. 107.730, Financings which constitute conflicts of interest, of the Small Business Administration Rules and Regulations (13 CFR 107). Solutions Capital I, L.P., proposes to acquire debt...

  4. 29 CFR 780.815 - Basic conditions of exemption; second part, processing of sugar beets, sugar-beet molasses...

    Science.gov (United States)

    2010-07-01

    ... sugar beets, sugar-beet molasses, sugarcane, or maple sap. 780.815 Section 780.815 Labor Regulations... Cotton and Processing of Sugar Beets, Sugar-Beet Molasses, Sugarcane, or Maple Sap into Sugar or Syrup... Quantities § 780.815 Basic conditions of exemption; second part, processing of sugar beets,...

  5. 75 FR 50845 - Privacy Act of 1974: Implementation of Exemptions; Department of Homeland Security/ALL-027 The...

    Science.gov (United States)

    2010-08-18

    ... / Wednesday, August 18, 2010 / Rules and Regulations#0;#0; ] DEPARTMENT OF HOMELAND SECURITY Office of the Secretary 6 CFR Part 5 Privacy Act of 1974: Implementation of Exemptions; Department of Homeland Security/ALL--027 The History of the Department of Homeland Security System of Records AGENCY: Privacy...

  6. 15 CFR 30.40 - Special exemptions for certain shipments to U.S. government agencies and employees.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Special exemptions for certain shipments to U.S. government agencies and employees. 30.40 Section 30.40 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN...

  7. 29 CFR 779.357 - May qualify as exempt 13(a)(2) establishments; classification of coal sales.

    Science.gov (United States)

    2010-07-01

    ...; classification of coal sales. 779.357 Section 779.357 Labor Regulations Relating to Labor (Continued) WAGE AND... for Certain Retail or Service Establishments Coal Dealers § 779.357 May qualify as exempt 13(a)(2) establishments; classification of coal sales. (a) General. A coal dealer's establishment may qualify as an...

  8. 77 FR 40142 - Applications for Exemption: Commercial Driver's License (CDL) and Hours-of-Service (HOS) of Drivers

    Science.gov (United States)

    2012-07-06

    ... May 21, 2012, and of Underwater Construction Corporation (Underwater) on May 29, 2012. On June 4, 2012....regulations.gov at any time, or to Room W12-140, DOT Building, 1200 New Jersey Ave. SE., Washington, DC... the case with the denials announced today. Applications for Exemption Rotel, Underwater,...

  9. 40 CFR 266.255 - When is your LLMW no longer eligible for the storage and treatment conditional exemption?

    Science.gov (United States)

    2010-07-01

    ... disposal conditional exemption at § 266.305. Storage Unit Closure ...-Level Mixed Waste Storage, Treatment, Transportation and Disposal. Reentry into Rcra § 266.255 When is... date your waste is subject to hazardous waste regulation under the relevant sections of 40 CFR...

  10. A Place for Block Play.

    Science.gov (United States)

    Moore, Gary T.

    1997-01-01

    Discusses the importance of block play--including its contributions to perceptual, fine motor, and cognitive development--and components of a good preschool block play area. Recommends unit blocks complemented by stacking blocks, toys, beads, cubes, and Brio wooden toys. Makes recommendations for space, size, locations and connections to other…

  11. Ganglion block. When and how?

    International Nuclear Information System (INIS)

    Increasing understanding of the anatomy and physiology of neural structures has led to the development of surgical and percutaneous neurodestructive methods in order to target and destroy various components of afferent nociceptive pathways. The dorsal root ganglia and in particular the ganglia of the autonomous nervous system are targets for radiological interventions. The autonomous nervous system is responsible for the regulation of organ functions, sweating, visceral and blood vessel-associated pain. Ganglia of the sympathetic chain and non-myelinized autonomous nerves can be irreversibly destroyed by chemical and thermal ablation. Computed tomography (CT)-guided sympathetic nerve blocks are well established interventional radiological procedures which lead to vasodilatation, reduction of sweating and reduction of pain associated with the autonomous nervous system. Sympathetic blocks are applied for the treatment of various vascular diseases including critical limb ischemia. Other indications for thoracic and lumbar sympathectomy include complex regional pain syndrome (CRPS), chronic tumor associated pain and hyperhidrosis. Neurolysis of the celiac plexus is an effective palliative pain treatment particularly in patients suffering from pancreatic cancer. Percutaneous dorsal root ganglion rhizotomy can be performed in selected patients with radicular pain that is resistant to conventional pharmacological and interventional treatment. (orig.)

  12. 40 CFR 91.1010 - Granting of exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Granting of exemptions. 91.1010 Section 91.1010 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Engines § 91.1010 Granting of exemptions. (a) If upon completion of the review of an exemption...

  13. 26 CFR 26.2632-1 - Allocation of GST exemption.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Allocation of GST exemption. 26.2632-1 Section...-1 Allocation of GST exemption. (a) General rule. Except as otherwise provided in this section, an individual or the individual's executor may allocate the individual's $1 million GST exemption at any...

  14. 9 CFR 590.650 - Exempted plant registration number.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Exempted plant registration number... Egg Products Plants § 590.650 Exempted plant registration number. Each plant processing egg products... Number” at the time the exemption approval is provided....

  15. 22 CFR 505.13 - General exemptions (Subsection (j)).

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true General exemptions (Subsection (j)). 505.13... exemptions (Subsection (j)). (a) General exemptions are available for systems of records which are maintained by the Central Intelligence Agency (Subsection (j)(1)), or maintained by an agency which performs...

  16. 21 CFR 801.127 - Medical devices; expiration of exemptions.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Medical devices; expiration of exemptions. 801.127 Section 801.127 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From Adequate Directions for Use § 801.127 Medical devices; expiration of exemptions. (a) If...

  17. 9 CFR 590.660 - Inspection of exempted plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of exempted plants. 590.660... Products Plants § 590.660 Inspection of exempted plants. Duly authorized representatives of the Administrator shall make such periodic inspections of exempted plants and records thereof as the...

  18. 77 FR 17107 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-03-23

    ... (KY) Travis J. Luce (MI) Jack D. Miller (OH) Eric M. Moats, Sr. (MD) Robert W. Nicks (NY) Joseph S... has statutory authority to exempt individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency has concluded that granting these exemption renewals...

  19. 7 CFR 301.85-2b - Exempted articles. 1

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Exempted articles. 1 301.85-2b Section 301.85-2b... § 301.85-2b Exempted articles. 1 1 The articles hereby exempted remain subject to applicable restrictions under other quarantines and other provisions of this subpart. (a) The following articles...

  20. 76 FR 50318 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-08-12

    ... the 17 exemption applications, FMCSA exempts, Danny F. Burnley, Bruce A. Cameron, Charles E. Carter... Agency has concluded that granting these exemptions will provide a level of safety that is equivalent to... hours are from 8:30 a.m. to 5 p.m. Monday through Friday, except Federal holidays....

  1. 26 CFR 54.4975-7 - Other statutory exemptions.

    Science.gov (United States)

    2010-04-01

    ... example, in the interest of certain selling shareholders. (3) Primary benefit requirement—(i) In general... current exempt loan. No person entitled to payment under the exempt loan shall have any right to assets of...) Right of first refusal. Qualifying employer securities acquired with proceeds of an exempt loan may,...

  2. 22 CFR 505.14 - Specific exemptions (Subsection (k)).

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Specific exemptions (Subsection (k)). 505.14... exemptions (Subsection (k)). The specific exemptions focus more on the nature of the records in the system of...) Subsection (k)(1). Records which are specifically authorized under criteria established under an...

  3. 46 CFR 531.10 - Excepted and exempted commodities.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Excepted and exempted commodities. 531.10 Section 531.10... ARRANGEMENTS Exceptions and Implementation § 531.10 Excepted and exempted commodities. (a) Statutory exceptions... or paper waste. (b) Commission exemptions. The following commodities and/or services are not...

  4. 17 CFR 36.3 - Exempt commercial markets.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Exempt commercial markets. 36... MARKETS § 36.3 Exempt commercial markets. (a) Notification. An electronic trading facility relying upon... electronic form, shall be labeled as “Notification of Operation as an Exempt Commercial Market,” and...

  5. 40 CFR 720.38 - Exemptions for test marketing.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Exemptions for test marketing. 720.38... CONTROL ACT PREMANUFACTURE NOTIFICATION Applicability § 720.38 Exemptions for test marketing. (a) Any person may apply for an exemption to manufacture or import a new chemical substance for test...

  6. 75 FR 60862 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-10-01

    ... renew exemptions at the end of the 2-year period. The comment period ended on September 16, 2010 (75 FR...-0174] Qualification of Drivers; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety... decision to renew the exemptions from the vision requirement in the Federal Motor Carrier...

  7. Effects of Block Scheduling

    Directory of Open Access Journals (Sweden)

    William R. Veal

    1999-09-01

    Full Text Available This study examined the effects of a tri-schedule on the academic achievement of students in a high school. The tri-schedule consists of traditional, 4x4 block, and hybrid schedules running at the same time in the same high school. Effectiveness of the schedules was determined from the state mandated test of basic skills in reading, language, and mathematics. Students who were in a particular schedule their freshman year were tested at the beginning of their sophomore year. A statistical ANCOVA test was performed using the schedule types as independent variables and cognitive skill index and GPA as covariates. For reading and language, there was no statistically significant difference in test results. There was a statistical difference mathematics-computation. Block mathematics is an ideal format for obtaining more credits in mathematics, but the block format does little for mathematics achievement and conceptual understanding. The results have content specific implications for schools, administrations, and school boards who are considering block scheduling adoption.

  8. Spice Blocks Melanoma Growth

    Science.gov (United States)

    Science Teacher, 2005

    2005-01-01

    Curcumin, the pungent yellow spice found in both turmeric and curry powders, blocks a key biological pathway needed for development of melanoma and other cancers, according to a study that appears in the journal Cancer. Researchers from The University of Texas M. D. Anderson Cancer Center demonstrate how curcumin stops laboratory strains of…

  9. Contaminated soil concrete blocks

    NARCIS (Netherlands)

    Korte, de A.C.J.; Brouwers, H.J.H.; Limbachiya, Mukesh C.; Kew, Hsein Y.

    2009-01-01

    According to Dutch law the contaminated soil needs to be remediated or immobilised. The main focus in this article is the design of concrete blocks, containing contaminated soil, that are suitable for large production, financial feasible and meets all technical and environmental requirements. In ord

  10. Compulsory school-entry vaccination laws and exemptions: who is opting out in ontario and why does it matter?

    Science.gov (United States)

    Mah, Catherine L; Guttmann, Astrid; McGeer, Allison; Krahn, Murray; Deber, Raisa B

    2010-05-01

    School-entry vaccination regulations are a policy instrument that has been widely used in some jurisdictions as a mechanism to ensure high immunization coverage rates. Exemptions to school-entry vaccination, which can be allowed on medical or non-medical grounds, present a number of ethical and policy challenges. In this paper, we consider the situation in Canada, where school-entry vaccination laws are rare. We present newly available aggregate-level registry data from Ontario comparing the use of medical and non-medical immunization exemptions to school-entry vaccination and the implications for population health.

  11. Assessment and recommendations for fissile-material packaging exemptions and general licenses within 10 CFR Part 71

    Energy Technology Data Exchange (ETDEWEB)

    Parks, C.V.; Hopper, C.M.; Lichtenwalter, J.L. [Oak Ridge National Lab., TN (United States)

    1998-07-01

    This report provides a technical and regulatory assessment of the fissile material general licenses and fissile material exemptions within Title 10 of the Code of Federal Regulations Part 71. The assessment included literature studies and calculational analyses to evaluate the technical criteria; review of current industry practice and concerns; and a detailed evaluation of the regulatory text for clarity, consistency and relevance. Recommendations for potential consideration by the Nuclear Regulatory Commission staff are provided. The recommendations call for a simplification and consolidation of the general licenses and a change in the technical criteria for the first fissile material exemptions.

  12. Edit Distance with Block Deletions

    OpenAIRE

    Dana Shapira; Storer, James A.

    2011-01-01

    Several variants of the edit distance problem with block deletions are considered. Polynomial time optimal algorithms are presented for the edit distance with block deletions allowing character insertions and character moves, but without block moves. We show that the edit distance with block moves and block deletions is NP-complete (Nondeterministic Polynomial time problems in which any given solution to such problem can be verified in polynomial time, and any NP problem can be converted into...

  13. Fermion-Scalar Conformal Blocks

    CERN Document Server

    Iliesiu, Luca; Poland, David; Pufu, Silviu S; Simmons-Duffin, David; Yacoby, Ran

    2015-01-01

    We compute the conformal blocks associated with scalar-scalar-fermion-fermion 4-point functions in 3D CFTs. Together with the known scalar conformal blocks, our result completes the task of determining the so-called `seed blocks' in three dimensions. Conformal blocks associated with 4-point functions of operators with arbitrary spins can now be determined from these seed blocks by using known differential operators.

  14. Exemption

    OpenAIRE

    Chant, Sylvia

    2014-01-01

    As part of her work on gender and poverty in The Gambia, Sylvia Chant has collaborated with Dr Isatou Touray, Founder and Executive Director of the NGO, GAMCOTRAP. GAMCOTRAP has since the 1980s been engaged, inter alia, in the struggle to eliminate Female Genital Mutilation (FGM), which affects over two-thirds of the female population in the country. Aside from GAMCOTRAP’s contributions to drafting a parliamentary bill to outlaw FGM, the organisation has also worked in several communities at ...

  15. Exclusion, exemption and clearance in the mining and minerals industry - A review of the concepts from a South African perspective

    International Nuclear Information System (INIS)

    The risks from mining and processing of ores is reviewed on a generic basis with particular reference to some of the confusions which can arise due to lack of consistency or common logic in the use of exclusion, exemption and clearance. The difference in exclusion and exemption are challenged by comparing doses received in high background radiation areas and the doses received from a mining practice. The common principle of risk to the human species is not applied consistently. The differences between IAEA recommendations and local regulatory conditions are compared, and the use of exemption levels as clearance levels is considered. A case study on management of mine tailings is presented with special focus on the use of clearance levels. In all areas of review the interpretation of regulation is subject to confusion resulting from inconsistencies which can distort free market economics. (author)

  16. ABC's of monitoring federal tax exemption.

    Science.gov (United States)

    Sanborn, A B; MacKelvie, C F

    1988-10-01

    Congress and the Internal Revenue Service (IRS) are taking a close look at the Internal Revenue Code (IRC) as it applies to Catholic institutions' activities. Although most Catholic institutions' exempt status is secured by reserved power organizational characteristics, it would behoove healthcare leaders to become familiar with the tax system and the IRS operation and, if necessary, make appropriate accommodations. They should understand what triggers an IRS audit and the audit process itself. The IRS subjects exempt institutions to organizational and operational tests. It deems that a healthcare entity is organized exclusively for an exempt (and charitable) purpose when that entity's articles of incorporation: 1. Limit the organization's purposes to charitable purposes. 2. Limit the organizations's activities to those which further its exempt purposes only, with other purposes furthered in only an insubstantial way. 3. Limit activities to those specified in IRC Section 501(c)(3). 4. Limit distribution of the organization's assets on dissolution to another organization with a like or similar exempt purpose. 5. Limit legislative and bar political activities Although most Catholic healthcare entities are "tax managed" conservatively, from an operational perspective, they often enter into transactions that the IRS considers "red flags." Some of these "red flag" transactions involve: Joint venture operations. Physician recruitment and physician handling plans. Rental/lease arrangements. Defined compensation plans. Hospital productivity plans. Profit-sharing plans. Contingent compensation arrangements. Acquisition, mergers, and divestitures. Taxable subsidiaries and unrelated business income. PMID:10290390

  17. NCCN Evidence Blocks.

    Science.gov (United States)

    Carlson, Robert W; Jonasch, Eric

    2016-05-01

    NCCN has developed a series of Evidence Blocks: graphics that provide ratings for each recommended treatment regimen in terms of efficacy, toxicity, quality and consistency of the supporting data, and affordability. The NCCN Evidence Blocks are currently available in 10 tumor types within the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines). At a glance, patients and providers can understand how a given treatment was assessed by the NCCN Guidelines Panel and get a sense of how a given treatment may match individual needs and preferences. Robert W. Carlson, MD, CEO of NCCN, described the reasoning behind this new feature and how the tool is used, and Eric Jonasch, MD, Professor of Genitourinary Medical Oncology at The University of Texas MD Anderson Cancer Center, and Vice Chair of the NCCN Kidney Cancer Panel, described its applicability in the management of metastatic renal cell carcinoma. PMID:27226499

  18. Insulin-like Growth Factor-binding Protein-3 (IGFBP-3) Blocks the Effects of Asthma by Negatively Regulating NF-κB Signaling through IGFBP-3R-mediated Activation of Caspases*♦

    OpenAIRE

    Lee, Yong-Chul; Jogie-Brahim, Sherryline; Lee, Dae-Yeol; Han, Jinfeng; Harada, Aki; Murphy, Liam J.; Oh, Youngman

    2011-01-01

    Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGFs. Here, we show that IGFBP-3 blocks specific physiological consequences of asthma in an IGF-independent manner in vitro and in vivo. IGFBP-3 treatment effectively reduced all physiological manifestations of asthma examined in vivo (airway hyper-responsiveness, cellular and patholog...

  19. SUPERFICIAL CERVICAL PLEXUS BLOCK

    Directory of Open Access Journals (Sweden)

    Komang Mega Puspadisari

    2014-01-01

    Full Text Available Superficial cervical plexus block is one of the regional anesthesia in  neck were limited to thesuperficial fascia. Anesthesia is used to relieve pain caused either during or after the surgery iscompleted. This technique can be done by landmark or with ultrasound guiding. The midpointof posterior border of the Sternocleidomastoid was identified and the prosedure done on thatplace or on the level of cartilage cricoid.

  20. 32 CFR 701.128 - Exemptions for specific Navy record systems.

    Science.gov (United States)

    2010-07-01

    ... confidentiality. (m) System identifier and name: (1) N05520-4, NCIS Investigative Files System. (2) Exemptions: (i..., Naval Clemency and Parole Board Files. (2) Exemption: (i) Parts of this system may be exempt pursuant to..., Trial/Government Counsel Files. (2) Exemption. Parts of this system may be exempt pursuant to 5...

  1. Managing access block.

    Science.gov (United States)

    Cameron, Peter; Scown, Paul; Campbell, Donald

    2002-01-01

    There is pessimism regarding the ability of the Acute Health Sector to manage access block for emergency and elective patients. Melbourne Health suffered an acute bed crisis in 2001 resulting in record ambulance diversions and emergency department (ED) delays. We conducted an observational study to reduce access block for emergency patients whilst maintaining elective throughput at Melbourne Health. This involved a clinician-led taskforce using previously proven principles for organisational change to implement 51 actions to improve patient access over a three-month period. The primary outcome measures were ambulance diversion, emergency patients waiting more than 12 hours for an inpatient bed, elective throughput and theatre cancellations. Despite a reduction in multi-day bed numbers all primary objectives were met, ambulance diversion decreased to minimal levels, 12-hour waits decreased by 40% and elective throughput was maintained. Theatre cancellations were also minimised. We conclude that access block can be improved by clinician-led implementation of proven process improvements over a short time frame. The ability to sustain change over the longer term requires further study.

  2. E-Block: A Tangible Programming Tool with Graphical Blocks

    Directory of Open Access Journals (Sweden)

    Danli Wang

    2013-01-01

    Full Text Available This paper designs a tangible programming tool, E-Block, for children aged 5 to 9 to experience the preliminary understanding of programming by building blocks. With embedded artificial intelligence, the tool defines the programming blocks with the sensors as the input and enables children to write programs to complete the tasks in the computer. The symbol on the programming block's surface is used to help children understanding the function of each block. The sequence information is transferred to computer by microcomputers and then translated into semantic information. The system applies wireless and infrared technologies and provides user with feedbacks on both screen and programming blocks. Preliminary user studies using observation and user interview methods are shown for E-Block's prototype. The test results prove that E-Block is attractive to children and easy to learn and use. The project also highlights potential advantages of using single chip microcomputer (SCM technology to develop tangible programming tools for children.

  3. Block Transfer Handbook: Constructing and Negotiating Block Transfer Agreements.

    Science.gov (United States)

    Finlay, Finola

    The purpose of this handbook is to provide resources for institutions or articulation committees who are engaged in the task of investigating the feasibility of block transfer agreements. Block transfer is the process whereby a block of credits is granted to students who have successfully completed a certificate, diploma, or cluster of courses…

  4. Banking services aid tax-exempt investments.

    Science.gov (United States)

    Forbes, R W; Leonard, P A

    1987-04-01

    Many not-for-profit hospitals are facing a severe capital shortage. Their traditional sources of funding--government grants, philanthropy, and appropriations--have dramatically declined. Increasingly, these hospitals are turning to the tax-exempt bond market for their capital. It is important for the financial manager to understand the elements and the process of tax-exempt financing. One crucial element is the investment banker who handles the project's financing. This article focuses on the financing services investment banking firms provide to hospitals and explains how much these services will cost. PMID:10280840

  5. Demographic Data - MDC_Block

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — A polygon feature class of Miami-Dade Census 2000 Blocks. Census blocks are areas bounded on all sides by visible and/or invisible features shown on a map prepared...

  6. Porous block nanofiber composite filters

    Energy Technology Data Exchange (ETDEWEB)

    Ginley, David S.; Curtis, Calvin J.; Miedaner, Alexander; Weiss, Alan J.; Paddock, Arnold

    2016-08-09

    Porous block nano-fiber composite (110), a filtration system (10) and methods of using the same are disclosed. An exemplary porous block nano-fiber composite (110) includes a porous block (100) having one or more pores (200). The porous block nano-fiber composite (110) also includes a plurality of inorganic nano-fibers (211) formed within at least one of the pores (200).

  7. One-Block CYRCA: an automated procedure for identifying multiple-block alignments from single block queries

    OpenAIRE

    Frenkel-Morgenstern, Milana; Singer, Alice; Bronfeld, Hagit; Pietrokovski, Shmuel

    2005-01-01

    One-Block CYRCA is an automated procedure for identifying multiple-block alignments from single block queries (). It is based on the LAMA and CYRCA block-to-block alignment methods. The procedure identifies whether the query blocks can form new multiple-block alignments (block sets) with blocks from a database or join pre-existing database block sets. Using pre-computed LAMA block alignments and CYRCA sets from the Blocks database reduces the computation time. LAMA and CYRCA are highly sensit...

  8. 40 CFR 93.126 - Exempt projects.

    Science.gov (United States)

    2010-07-01

    ... in 23 CFR part 771. Air Quality Continuation of ride-sharing and van-pooling promotion activities at... that action. Noise attenuation. Emergency or hardship advance land acquisitions (23 CFR 710.503... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Exempt projects. 93.126 Section...

  9. 22 CFR 126.5 - Canadian exemptions.

    Science.gov (United States)

    2010-04-01

    ..., the permanent and temporary export to Canada without a license of defense articles and related technical data identified in 22 CFR 121.1. The above exemption is subject to the following limitations... in 22 CFR 121.1 continuing to require a license are: (1) All classified articles, technical data...

  10. 48 CFR 22.807 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Equal Employment Opportunity 22.807 Exemptions. (a) Under..., however, discriminate among Indians on the basis of religion, sex, or tribal affiliation, and the use of... the Secretary of Labor, and applicable clauses in the contract. (5) Facilities not connected...

  11. 21 CFR 710.9 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... REGISTRATION OF COSMETIC PRODUCT ESTABLISHMENTS § 710.9 Exemptions. The following classes of persons are not... registration is not justified: (a) Beauty shops, cosmetologists, retailers, pharmacies, and other persons and organizations that compound cosmetic products at a single location and administer, dispense, or distribute...

  12. 10 CFR 171.11 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... avoidance of interest and penalty charges. If a partial or full exemption is granted, any overpayment will... following factors: (1) Age of the reactor; (2) Number of customers in rate base; (3) Net increase in KWh cost for each customer directly related to the annual fee assessed under this part; and (4) Any...

  13. 49 CFR 1507.3 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... exempt from the access provisions of subsection (d). (c) Personnel Background Investigation File System (DHS/TSA 004). The Personnel Background Investigation File System (PBIFS) (DHS/TSA 004) enables TSA to... Traveler Operations Files (DHS/TSA 015). The purpose of this system is to pre-screen and...

  14. 39 CFR 266.9 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... Records, USPS 500.300; Inspection Service Investigative File System, USPS 700.000; Mail Cover Program... Management Records, USPS 500.300; Inspection Service Investigative File System, USPS 700.000; Mail Cover... File System, USPS 700.000; and Inspector General Investigative Records, USPS 700.300 are exempt...

  15. 50 CFR 679.6 - Exempted fisheries.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Exempted fisheries. 679.6 Section 679.6 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE (CONTINUED) FISHERIES OF THE EXCLUSIVE ECONOMIC ZONE OFF ALASKA General §...

  16. 21 CFR 21.61 - Exempt systems.

    Science.gov (United States)

    2010-04-01

    ... criminal law enforcement purposes, in the Food and Drug Administration Privacy Act Record Systems listed in... records compiled by the Food and Drug Administration in a criminal law enforcement investigation where the... enforcement purposes, including criminal law enforcement purposes, are exempt under 5 U.S.C. 552a(j)(2) and...

  17. 9 CFR 130.49 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... States for testing for foreign animal diseases. (b) ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Exemptions. 130.49 Section 130.49 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

  18. 5 CFR 1632.5 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... confidential source and, in the case of a record compiled by a criminal law enforcement authority in the course... tribunal, or an arbitration, or the initiation, conduct, or disposition of a particular case of formal... MEETINGS § 1632.5 Exemptions. (a) Except in a case where the Board finds that the public interest...

  19. 18 CFR 1301.7 - Exempt records.

    Science.gov (United States)

    2010-04-01

    ... order to be kept secret in the interest of national defense or foreign policy and (ii) Are in fact... and practices of TVA; (3) Specifically exempted from disclosure by statute; (4) Trade secrets and...) Personnel and medical files and similar files, the disclosure of which would constitute a...

  20. 18 CFR 401.112 - Exempt information.

    Science.gov (United States)

    2010-04-01

    ...; (b) Specifically exempted from disclosure by statute; (c) Trade secrets and commercial or financial... secret may consist of any formula, pattern, device, or compilation of information which is used in one's...) Personnel and medical files and similar files the disclosure of which would constitute a clearly...

  1. 20 CFR 401.85 - Exempt systems.

    Science.gov (United States)

    2010-04-01

    ... record compiled by SSA for criminal law enforcement purposes in a system of records exempt under..., the Investigatory Material Compiled for Law Enforcement Purposes System, SSA. (ii) Pursuant to... Purposes System, SSA; and, (B) The Suitability for Employment Records, SSA. (iv) Pursuant to subsection...

  2. 40 CFR 147.102 - Aquifer exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Aquifer exemptions. 147.102 Section 147.102 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS...) Granite Point. (ii) McArthur River Field. (iii) Middle Ground Shoal Field. (iv) Trading Bay Field. (3)...

  3. 7 CFR 1219.8 - Exempt handler.

    Science.gov (United States)

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.8 Exempt... Hass avocados purchased by the person have already been subject to assessments under the Order....

  4. 7 CFR 57.100 - Specific exemptions.

    Science.gov (United States)

    2010-01-01

    ... section, the exemptions do not apply to restricted eggs when prohibited by State or local law: And... are allowed by the tolerances in the official standards for U.S. Consumer Grade B shell eggs; (b) (c... directly to a household consumer exclusively for use by such consumer and members of his household and...

  5. 45 CFR 5b.11 - Exempt systems.

    Science.gov (United States)

    2010-10-01

    .../SSA; (B) The Criminal Investigations File, HHS/SSA; and, (C) The Program Integrity Case Files, HHS/SSA... records only in compelling cases. (b) Specific systems of records exempted. (1) Those systems of records... records and correction or amendment of records. (iii) 5 U.S.C. 552a(e)(4) (G) and (H) which...

  6. The wild tapered block bootstrap

    DEFF Research Database (Denmark)

    Hounyo, Ulrich

    In this paper, a new resampling procedure, called the wild tapered block bootstrap, is introduced as a means of calculating standard errors of estimators and constructing confidence regions for parameters based on dependent heterogeneous data. The method consists in tapering each overlapping block...... of the series first, the applying the standard wild bootstrap for independent and heteroscedastic distrbuted observations to overlapping tapered blocks in an appropriate way. Its perserves the favorable bias and mean squared error properties of the tapered block bootstrap, which is the state-of-the-art block......-order asymptotic validity of the tapered block bootstrap as well as the wild tapered block bootstrap approximation to the actual distribution of the sample mean is also established when data are assumed to satisfy a near epoch dependent condition. The consistency of the bootstrap variance estimator for the sample...

  7. Block Voter Model

    CERN Document Server

    Sampaio, C I N

    2011-01-01

    We introduce and study the block voter model with noise on two-dimensional square lattices using Monte Carlo simulations and finite-size scaling techniques. The model is defined by an outflow dynamics where a central set of $N_{PCS}$ spins, here denoted by persuasive cluster spins (PCS), tries to influence the opinion of their neighbouring counterparts. We consider the collective behaviour of the entire system with varying PCS size. When $N_{PCS}>2$, the system exhibits an order-disorder phase transition at a critical noise parameter $q_{c}$ which is a monotonically increasing function of the size of the persuasive cluster. We conclude that how large the PCS is more power of persuasion it has. It also seems that the resulting critical behaviour is Ising-like independent of the range of the interactions.

  8. Spintronics: Conceptual Building Blocks

    Science.gov (United States)

    Ansermet, J.-Ph.

    The purpose of this introduction to spintronics is to provide some elementary description of its conceptual building blocks. Thus, it is intended for a newcomer to the field. After recalling rudimentary descriptions of spin precession and spin relaxation, spin-dependent transport is treated within the Boltzmann formalism. This suffices to introduce key notions such as the spin asymmetry of the conductivities in the two-current model, the spin diffusion length, and spin accumulation. Two basic mechanisms of spin relaxation are then presented, one arising from spin-orbit scattering and the other from electron-magnon collisions. Finally, the action of a spin-polarized current on magnetization is presented in a thermodynamics framework. This introduces the notion of spin torque and the characteristic length scale over which the transverse spin polarization of conduction electron decays as it is injected into a magnet.

  9. Photovoltaic building blocks

    DEFF Research Database (Denmark)

    Hanberg, Peter Jesper; Jørgensen, Anders Michael

    2014-01-01

    it directcompetitive with fossil energy sources a further reduction is needed. By increasing the efficiency of the solar cells one gain an advantage through the whole chain of cost. So that per produced Watt of power less material is spent, installation costs are lower, less area is used etc. With an average...... efficiency of about 15% for commercial Silicon solar cells there is still much to gain. DTU Danchip provides research facilities, equipment and expertise for the building blocks that comprises fabricating the efficient solar cell. In order to get more of the sun light into the device we provide thin film......Photovoltaics (PV), better known as solar cells, are now a common day sight on many rooftops in Denmark.The installed capacity of PV systems worldwide is growing exponentially1 and is the third most importantrenewable energy source today. The cost of PV is decreasing fast with ~10%/year but to make...

  10. Atomic Basic Blocks

    Science.gov (United States)

    Scheler, Fabian; Mitzlaff, Martin; Schröder-Preikschat, Wolfgang

    Die Entscheidung, einen zeit- bzw. ereignisgesteuerten Ansatz für ein Echtzeitsystem zu verwenden, ist schwierig und sehr weitreichend. Weitreichend vor allem deshalb, weil diese beiden Ansätze mit äußerst unterschiedlichen Kontrollflussabstraktionen verknüpft sind, die eine spätere Migration zum anderen Paradigma sehr schwer oder gar unmöglich machen. Wir schlagen daher die Verwendung einer Zwischendarstellung vor, die unabhängig von der jeweils verwendeten Kontrollflussabstraktion ist. Für diesen Zweck verwenden wir auf Basisblöcken basierende Atomic Basic Blocks (ABB) und bauen darauf ein Werkzeug, den Real-Time Systems Compiler (RTSC) auf, der die Migration zwischen zeit- und ereignisgesteuerten Systemen unterstützt.

  11. Exemption of electricity-intensive network users pursuant to paragraph 19 II 2 of the Electricity Network Charges Ordinance. Reallocation sleaze regulation and the law.; Befreiung stromintensiver Netznutzer gem. paragraph 19 II 2 StromNEV. Die Umlagenfilzregulierung und das Recht

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, Lukas [Bonn Univ. (Germany). Zentrum fuer Europaeische Integrationsforschung; Koenig, Christian [Bonn Univ. (Germany). Zentrum fuer Europaeische Integrationsforschung; Bonn Univ. (Germany). Rechts- und Staatswissenschaftliche Fakultaet

    2012-12-13

    The last major amendment of the energy economy laws in the summer of 2011 included changes to paragraph 19 II 2 of the Electricity Network Charges Ordinance. Whereas previously individual agreements on network charges had only been permissible in cases of atypical network use, the present amendment now entirely exempts electricity-intensive customers from network charges. If the loss in revenue which results from the exemption of large network users is socialised through a reallocation mechanism and is thus borne by the entirety of network users, then such a reallocation scheme will have the economic effect of a consumer tax serving the redistribution of wealth from bottom to top under the pretence of securing international competitiveness and employment, circumventing the arduous route via the national fiscal budget. There is nothing like the law, especially the law on EU subsidies, as a means of stabilising this lobby-driven regulatory roller-coaster ride.

  12. ADVANCES IN INTEGRATING INSECT GROWTH REGULATORS INTO STORAGE PEST MANAGEMENT

    Science.gov (United States)

    Insect growth regulators (IGRs) are insecticides that mimic insect-produced hormones that regulate the developmental process. They generally have little or no mammalian toxicity, and are considered reduced-risk insecticides that are often exempt from tolerance requirements of regulatory agencies. Al...

  13. 77 FR 8721 - Home Mortgage Disclosure (Regulation C)

    Science.gov (United States)

    2012-02-15

    ... PROTECTION 12 CFR Part 1003 RIN 3170-AA06 Home Mortgage Disclosure (Regulation C) AGENCY: Bureau of Consumer... requirements of Regulation C (Home Mortgage Disclosure) to reflect a change in the asset-size exemption... 1975, as amended (HMDA; 12 U.S.C. 2801 et seq.) requires most mortgage lenders located in...

  14. 7 CFR 906.120 - Fruit exempt from regulations.

    Science.gov (United States)

    2010-01-01

    ...) Each fiscal period the handler submits prior to such handling a written application to the committee on.... Combination (with not less than 60 percent, by count, of the oranges in any lot grading at least U.S. No.1... writing of its decision: Provided, That if it approves a handler's request, it shall issue a...

  15. The Block-block Bootstrap: Improved Asymptotic Refinements

    OpenAIRE

    Donald W.K. Andrews

    2002-01-01

    The asymptotic refinements attributable to the block bootstrap for time series are not as large as those of the nonparametric iid bootstrap or the parametric bootstrap. One reason is that the independence between the blocks in the block bootstrap sample does not mimic the dependence structure of the original sample. This is the join-point problem. In this paper, we propose a method of solving this problem. The idea is not to alter the block bootstrap. Instead, we alter the original sample sta...

  16. Convergence rates of empirical block length selectors for block bootstrap

    OpenAIRE

    Nordman, Daniel J.; Lahiri, Soumendra N.

    2014-01-01

    We investigate the accuracy of two general non-parametric methods for estimating optimal block lengths for block bootstraps with time series – the first proposed in the seminal paper of Hall, Horowitz and Jing (Biometrika 82 (1995) 561–574) and the second from Lahiri et al. (Stat. Methodol. 4 (2007) 292–321). The relative performances of these general methods have been unknown and, to provide a comparison, we focus on rates of convergence for these block length selectors for the moving block ...

  17. Large Block Test Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lin, W

    2001-12-01

    This report documents the Large-Block Test (LBT) conducted at Fran Ridge near Yucca Mountain, Nevada. The LBT was a thermal test conducted on an exposed block of middle non-lithophysal Topopah Spring tuff (Tptpmn) and was designed to assist in understanding the thermal-hydrological-mechanical-chemical (THMC) processes associated with heating and then cooling a partially saturated fractured rock mass. The LBT was unique in that it was a large (3 x 3 x 4.5 m) block with top and sides exposed. Because the block was exposed at the surface, boundary conditions on five of the six sides of the block were relatively well known and controlled, making this test both easier to model and easier to monitor. This report presents a detailed description of the test as well as analyses of the data and conclusions drawn from the test. The rock block that was tested during the LBT was exposed by excavation and removal of the surrounding rock. The block was characterized and instrumented, and the sides were sealed and insulated to inhibit moisture and heat loss. Temperature on the top of the block was also controlled. The block was heated for 13 months, during which time temperature, moisture distribution, and deformation were monitored. After the test was completed and the block cooled down, a series of boreholes were drilled, and one of the heater holes was over-cored to collect samples for post-test characterization of mineralogy and mechanical properties. Section 2 provides background on the test. Section 3 lists the test objectives and describes the block site, the site configuration, and measurements made during the test. Section 3 also presents a chronology of events associated with the LBT, characterization of the block, and the pre-heat analyses of the test. Section 4 describes the fracture network contained in the block. Section 5 describes the heating/cooling system used to control the temperature in the block and presents the thermal history of the block during the test

  18. New requirements for hospitals to maintain tax-exempt status.

    Science.gov (United States)

    Smith, Pamela C; Noe, Kelly

    2012-01-01

    Tax-exempt hospitals are now facing more legislative requirements to maintain tax-exempt status. This article outlines each of these requirements imposed by the Patient Protection Act of 2010. Health care administrators, executives, and consultants must be aware of these new laws to ensure each facility is capable of maintaining tax-exempt status. Despite the issuance of new requirements, a conclusive definition of charity does not exist. Therefore, the debate surrounding charity care and the justification for tax-exempt status will continue. PMID:22515041

  19. Tax-exempt bank loans still an option for providers.

    Science.gov (United States)

    Ostlund, Grant; Cheney, John E

    2011-07-01

    In evaluating the potential for tax-exempt bank financing, healthcare organizations should carefully consider: Pricing. Loan structure. Security requirements (such as financial covenants and default remedies).

  20. The Subject of Exemption - through discourses of normalisation and individualisation

    DEFF Research Database (Denmark)

    Hamre, Bjørn; Fristrup, Tine; Christensen, Gerd

    2016-01-01

    This article examines the constructions of the deviant subject in Danish Foucauldian educational research. Following the work of Foucault, we argue that the deviant subject, on the one hand, could be considered as a subject of exemption. In this case, exemption is deduced from Foucault’s understa......This article examines the constructions of the deviant subject in Danish Foucauldian educational research. Following the work of Foucault, we argue that the deviant subject, on the one hand, could be considered as a subject of exemption. In this case, exemption is deduced from Foucault...

  1. SRP meeting: the Radioactive Substances Act and Exemption Orders, London, 16 January 2001

    International Nuclear Information System (INIS)

    The SRP conference on the Radioactive Substances Act (RSA) and Exemption Orders was held in the Scientific Societies Lecture Theatre in London on 16 January 2001. The proposed changes to RSA93 were put forward in two draft Statutory Instruments, 'Proposals for Radioactive Substances (Basic Safety Standards) (England and Wales) Regulation 2000' and the 'Radioactive Substances (Basic Safety Standards) (England and Wales) Directive 2000'. The former is limited to the changes for clocks and watches and requires prior authorisation for the disposal of all radioactive substances arising from practices subject to reporting. The latter places legally binding duties on the EA in the administration of the Act. This includes legal obligation for the EA to ensure that when granting RSA authorisations, resulting exposures are ALARA, that dose limits for members of the public are complied with, that dose constraints are considered where appropriate and that undertakings discharge their responsibilities under the Act. Mr. Ciaran McDonnell from the NRPB presented their findings on the current application of some of the existing Exemption Orders (excluding MOD use), and discussed the impact of possible changes. The main advantage of he Exemption Orders was considered to be avoiding the need for registration. Mr. McDonnell also stated that for some users, a move to prior notification on first use of an Exemption Order may be acceptable, but a requirement for further notification may prove impracticable. The NRPB found a reluctance by users to make full use of the provision for waste disposal. Instead many chose to use authorised disposal routes, for example Safeguard. Therefore, provided these disposal costs did not increase excessively, he felt that the removal of some of the current disposal options may not have a serious effect for small industrial users. However, he also stated that this view may not be shared by those in different work areas, e.g. schools/hospitals. Although

  2. Covariant Approaches to Superconformal Blocks

    CERN Document Server

    Fitzpatrick, A Liam; Khandker, Zuhair U; Li, Daliang; Poland, David; Simmons-Duffin, David

    2014-01-01

    We develop techniques for computing superconformal blocks in 4d superconformal field theories. First we study the super-Casimir differential equation, deriving simple new expressions for superconformal blocks for 4-point functions containing chiral operators in theories with N-extended supersymmetry. We also reproduce these results by extending the "shadow formalism" of Ferrara, Gatto, Grillo, and Parisi to supersymmetric theories, where superconformal blocks can be represented as superspace integrals of three-point functions multiplied by shadow three-point functions.

  3. Dimensional Reduction for Conformal Blocks

    CERN Document Server

    Hogervorst, Matthijs

    2016-01-01

    We consider the dimensional reduction of a CFT, breaking multiplets of the d-dimensional conformal group SO(d+1,1) up into multiplets of SO(d,1). This leads to an expansion of d-dimensional conformal blocks in terms of blocks in d-1 dimensions. In particular, we obtain a formula for 3d conformal blocks as an infinite sum over 2F1 hypergeometric functions with closed-form coefficients.

  4. Adductor Canal Block versus Femoral Nerve Block and Quadriceps Strength

    DEFF Research Database (Denmark)

    Jæger, Pia Therese; Nielsen, Zbigniew Jerzy Koscielniak; Henningsen, Lene Marianne;

    2013-01-01

    : The authors hypothesized that the adductor canal block (ACB), a predominant sensory blockade, reduces quadriceps strength compared with placebo (primary endpoint, area under the curve, 0.5-6 h), but less than the femoral nerve block (FNB; secondary endpoint). Other secondary endpoints were...

  5. Special report on taxation. IRS issues stricter guidelines for audits of tax-exempt hospitals.

    Science.gov (United States)

    Solomon, J E

    1992-07-01

    The new audit guidelines serve as yet another reminder to tax-exempt hospitals that great care must be taken in structuring and documenting business arrangements with physicians and executives so as to withstand scrutiny by the IRS with regard to exempt status. Since increased census and utilization, and enhancement of the hospital's financial position, are no longer acceptable justifications for such activities as physician recruitment incentives (being suggestive of payment for referrals), it is important that hospitals make an effort to ensure that board minutes, recruitment policies, internal memoranda, and other documentation set forth the reasons--other than the benefits to the institution's bottom line--for having entered into such transactions. Hospitals must establish and document a community need for each physician recruited. Hospitals that actively recruit should be armed with studies evaluating recruiting needs in each clinical area, based on objective criteria, taking into consideration managed care contracting needs and the provision of services to the poor and needy. Finally, hospitals should re-examine all joint ventures and other business relationships with physicians to determine whether such arrangements resulted from arm's length negotiation, involve fair market value for goods and services, and conform, insofar as possible, with the Medicare fraud and abuse safe harbor regulations. Under GCM 39862 and the new guidelines, "aggressive" arrangements may not only create exposure under fraud and abuse laws, but could jeopardize the provider's tax-exempt status as well. PMID:10119510

  6. 24 CFR 1000.28 - May a self-governance Indian tribe be exempted from the applicability of § 1000.26?

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false May a self-governance Indian tribe be exempted from the applicability of § 1000.26? 1000.28 Section 1000.28 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR PUBLIC AND INDIAN HOUSING, DEPARTMENT...

  7. 18 CFR 366.4 - FERC-65, notification of holding company status, FERC-65A, exemption notification, and FERC-65B...

    Science.gov (United States)

    2010-04-01

    ... meet the definition of a holding company as provided by § 366.1 as of February 8, 2006 shall notify the... of holding company status, FERC-65A, exemption notification, and FERC-65B, waiver notification. 366.4... OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL POWER ACT...

  8. 78 FR 32294 - Main Street Capital ll, L.P., License No. 06/06-0332; Notice Seeking Exemption Under Section 312...

    Science.gov (United States)

    2013-05-29

    ... ADMINISTRATION Main Street Capital ll, L.P., License No. 06/06-0332; Notice Seeking Exemption Under Section 312... Capital ll, L.P., 1300 Post Oak Boulevard, Suite 800, Houston, TX 77056, a Federal Licensee under the... Regulations (13 CFR 107.730). Main Street Capital ll, L.P. proposes to provide loan and equity financing...

  9. Multi-block and path modelling procedures

    DEFF Research Database (Denmark)

    Høskuldsson, Agnar

    2008-01-01

    The author has developed a unified theory of path and multi-block modelling of data. The data blocks are arranged in a directional path. Each data block can lead to one or more data blocks. It is assumed that there is given a collection of input data blocks. Each of them is supposed to describe one...... or more intermediate data blocks. The output data blocks are those that are at the ends of the paths and have no succeeding data blocks. The optimisation procedure finds weights for the input data blocks so that the size of the total loadings for the output data blocks are maximised. When the optimal...... weight vectors have been determined, the score and loading vectors for the data blocks in the path are determined. Appropriate adjustment of the data blocks is carried out at each step. Regression coefficients are computed for each data block that show how the data block is estimated by data blocks...

  10. OPAL Various Lead Glass Blocks

    CERN Multimedia

    These lead glass blocks were part of a CERN detector called OPAL (one of the four experiments at the LEP particle detector). OPAL uses some 12 000 blocks of glass like this to measure particle energies in the electromagnetic calorimeter. This detector measured the energy deposited when electrons and photons were slowed down and stopped.

  11. Block storage subsystem performance analysis

    CERN Document Server

    CERN. Geneva

    2016-01-01

    You feel that your service is slow because of the storage subsystem? But there are too many abstraction layers between your software and the raw block device for you to debug all this pile... Let's dive on the platters and check out how the block storage sees your I/Os! We can even figure out what those patterns are meaning.

  12. Classical Virasoro irregular conformal block

    CERN Document Server

    Rim, Chaiho

    2015-01-01

    Virasoro irregular conformal block with arbitrary rank is obtained for the classical limit or equivalently Nekrasov-Shatashvili limit using the beta-deformed irregular matrix model (Penner-type matrix model for the irregular conformal block). The same result is derived using the generalized Mathieu equation which is equivalent to the loop equation of the irregular matrix model.

  13. AtMyb7, a subgroup 4 R2R3 Myb, negatively regulates ABA-induced inhibition of seed germination by blocking the expression of the bZIP transcription factor ABI5

    KAUST Repository

    Kim, Junhyeok

    2014-08-27

    Various Myb proteins have been shown to play crucial roles in plants, including primary and secondary metabolism, determination of cell fate and identity, regulation of development and involvement in responses to biotic and abiotic stresses. The 126 R2R3 Myb proteins (with two Myb repeats) have been found in Arabidopsis; however, the functions of most of these proteins remain to be fully elucidated. In the present study, we characterized the function of AtMyb7 using molecular biological and genetic analyses. We used qRT-PCR to determine the levels of stress-response gene transcripts in wild-type and atmyb7 plants. We showed that ArabidopsisAtMyb7 plays a critical role in seed germination. Under abscisic acid (ABA) and high-salt stress conditions, atmyb7 plants showed a lower germination rate than did wild-type plants. Furthermore, AtMyb7 promoter:GUS seeds exhibited different expression patterns in response to variations in the seed imbibition period. AtMyb7 negatively controls the expression of the gene encoding bZIP transcription factor, ABI5, which is a key transcription factor in ABA signalling and serves as a crucial regulator of germination inhibition in Arabidopsis. © 2014 John Wiley & Sons Ltd.

  14. 40 CFR 180.1119 - Azadirachtin; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Azadirachtin; exemption from the... Exemptions From Tolerances § 180.1119 Azadirachtin; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for the biochemical azadirachtin, which...

  15. 40 CFR 180.1222 - Sucrose octanoate esters; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sucrose octanoate esters; exemption... FOOD Exemptions From Tolerances § 180.1222 Sucrose octanoate esters; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of...

  16. 40 CFR 180.1262 - Sorbitol octanoate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sorbitol octanoate; exemption from the... Exemptions From Tolerances § 180.1262 Sorbitol octanoate; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of sorbitol octanoate in or on...

  17. 40 CFR 180.1160 - Jojoba oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Jojoba oil; exemption from the... Exemptions From Tolerances § 180.1160 Jojoba oil; exemption from the requirement of a tolerance. The insecticide and spray tank adjuvant jojoba oil is exempted from the requirement of a tolerance in or on...

  18. 26 CFR 48.4041-20 - Partially exempt methanol and ethanol fuel.

    Science.gov (United States)

    2010-04-01

    ... gasoline to produce a partially exempt methanol or ethanol fuel. (e) Later blending. If a partially exempt... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Partially exempt methanol and ethanol fuel. 48... Partially exempt methanol and ethanol fuel. (a) In general. Under section 4041(m), the sale or use...

  19. 40 CFR 180.1233 - Potassium sorbate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Potassium sorbate; exemption from the... Exemptions From Tolerances § 180.1233 Potassium sorbate; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of potassium sorbate....

  20. 40 CFR 180.1176 - Sodium bicarbonate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sodium bicarbonate; exemption from the... Exemptions From Tolerances § 180.1176 Sodium bicarbonate; exemption from the requirement of a tolerance. The biochemical pesticide sodium bicarbonate is exempted from the requirement of a tolerance in or on all...

  1. 76 FR 9853 - Parts and Accessories Necessary for Safe Operation; Brakes; Application for Exemption From...

    Science.gov (United States)

    2011-02-22

    ... Exemption From Innovative Electronics; Notice of application for exemption; request for comments (76 FR 7623...; Application for Exemption From Innovative Electronics; Correction AGENCY: Federal Motor Carrier Safety.... SUMMARY: This document corrects the docket number for FMCSA's notice of ] application for exemption...

  2. 29 CFR 794.143 - Work exempt under another section of the Act.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Work exempt under another section of the Act. 794.143... Application of Exemption to Employees § 794.143 Work exempt under another section of the Act. Where an employee performs work during his workweek, some of which is exempt under one section of the Act, and...

  3. 40 CFR 180.1291 - Cold pressed neem oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Cold pressed neem oil; exemption from... FOOD Exemptions From Tolerances § 180.1291 Cold pressed neem oil; exemption from the requirement of a tolerance. Residues of the biochemical pesticide cold pressed neem oil are exempt from the requirement of...

  4. 40 CFR 180.1197 - Hydrogen peroxide; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Hydrogen peroxide; exemption from the... Exemptions From Tolerances § 180.1197 Hydrogen peroxide; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of hydrogen peroxide in or on...

  5. 49 CFR 1105.12 - Sample newspaper notices for abandonment exemption cases.

    Science.gov (United States)

    2010-10-01

    ... 20423, a notice of exemption under 49 CFR 1152 Subpart F—Exempt Abandonments permitting the (abandonment... 49 Transportation 8 2010-10-01 2010-10-01 false Sample newspaper notices for abandonment exemption... OF ENVIRONMENTAL LAWS § 1105.12 Sample newspaper notices for abandonment exemption cases. In...

  6. 40 CFR 180.1145 - Pseudomonas syringae; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pseudomonas syringae; exemption from... FOOD Exemptions From Tolerances § 180.1145 Pseudomonas syringae; exemption from the requirement of a tolerance. Pseudomonas syringae is exempted from the requirement of a tolerance on all raw...

  7. 40 CFR 180.1090 - Lactic acid; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Lactic acid; exemption from the... Exemptions From Tolerances § 180.1090 Lactic acid; exemption from the requirement of a tolerance. Lactic acid (2-hydroxypropanoic acid) is exempted from the requirement of a tolerance when used as a plant...

  8. 40 CFR 180.905 - Pesticide chemicals; exemptions from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pesticide chemicals; exemptions from... PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Exemptions From Tolerances § 180.905 Pesticide chemicals; exemptions from the requirement of...

  9. The Shamrock lumbar plexus block

    DEFF Research Database (Denmark)

    Sauter, Axel R; Ullensvang, Kyrre; Niemi, Geir;

    2015-01-01

    BACKGROUND: The Shamrock technique is a new method for ultrasound-guided lumbar plexus blockade. Data on the optimal local anaesthetic dose are not available. OBJECTIVE: The objective of this study is to estimate the effective dose of ropivacaine 0.5% for a Shamrock lumbar plexus block. DESIGN: A...... prospective dose-finding study using Dixon's up-and-down sequential method. SETTING: University Hospital Orthopaedic Anaesthesia Unit. INTERVENTION: Shamrock lumbar plexus block performance and block assessment were scheduled preoperatively. Ropivacaine 0.5% was titrated with the Dixon and Massey up......-and-down method using a stepwise change of 5 ml in each consecutive patient. Combined blocks of the femoral, the lateral femoral cutaneous and the obturator nerve were prerequisite for a successful lumbar plexus block. PATIENTS: Thirty patients scheduled for lower limb orthopaedic surgery completed the study...

  10. Federal Environmental Regulations Impacting Hydrocarbon Exploration, Drilling, and Production Operations

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, Herbert B.; Johnson, William I.

    1999-04-27

    Waste handling and disposal from hydrocarbon exploration, drilling, and production are regulated by the US Environmental Protection Agency (EPA) through federal and state regulations and/or through implementation of federal regulations. Some wastes generated in these operations are exempt under the Resource Conservation and Recovery Act (RCRA) but are not exempt under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), Superfund Amendments and Reauthorization Act (SARA), and other federal environmental laws. Exempt wastes remain exempt only if they are not mixed with hazardous wastes or hazardous substances. Once mixture occurs, the waste must be disposed as a hazardous material in an approved hazardous waste disposal facility. Before the Clean Air Act as amended in 1990, air emissions from production, storage, steam generation, and compression facilities associated with hydrocarbon exploration, drilling, and production industry were not regulated. A critical proposed regulatory change which will significantly effect Class II injection wells for disposal of produced brine and injection for enhanced oil recovery is imminent. Federal regulations affecting hydrocarbon exploration, drilling and production, proposed EPA regulatory changes, and a recent significant US Court of Appeals decision are covered in this report. It appears that this industry will, in the future, fall under more stringent environmental regulations leading to increased costs for operators.

  11. Exemption 4: Trade Secrets under the Freedom of Information Act.

    Science.gov (United States)

    Selby, Holly E.

    Exemption 4 of the Freedom of Information Act (FOIA) protects from disclosure by government agencies privileged and confidential trade secrets and commercial or financial information. Based on early Exemption 4 litigation, courts have devised a "substantial competitive harm test" to decide whether requested information should be covered by the…

  12. 5 CFR 551.206 - Administrative exemption criteria.

    Science.gov (United States)

    2010-01-01

    ... judgment must be more than the use of skill in applying well-established techniques, procedures, or... knowledge or skills does not preclude exemption. Such manuals and procedures provide guidance in addressing... exempt or nonexempt. For example, criminal investigators who perform work directly related to...

  13. 10 CFR 34.111 - Applications for exemptions.

    Science.gov (United States)

    2010-01-01

    ... NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Exemptions § 34.111 Applications for exemptions. The Commission may, upon... endanger life or property or the common defense and security and is otherwise in the public interest....

  14. 41 CFR 51-9.102-1 - Specific exemptions.

    Science.gov (United States)

    2010-07-01

    ...-General Policy § 51-9.102-1 Specific exemptions. Systems of records maintained by the Committee which have... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Specific exemptions. 51-9.102-1 Section 51-9.102-1 Public Contracts and Property Management Other Provisions Relating to...

  15. 77 FR 63411 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-16

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... diabetes exemption program established on September 3, 2003 (68 FR 52441).\\1\\ The revision must provide...

  16. 77 FR 33554 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-06

    ... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... diabetes exemption program established on September 3, 2003 (68 FR 52441).\\1\\ The revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described...

  17. 75 FR 77947 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-12-14

    ... exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... revise its diabetes exemption program established on September 3, 2003 (68 FR 52441) \\1\\. The...

  18. 41 CFR 109-39.107 - Limited exemptions.

    Science.gov (United States)

    2010-07-01

    ... Discontinuance of Interagency Fleet Management Systems § 109-39.107 Limited exemptions. The Director, Office of Administrative Services and heads of field organizations for their respective organizations shall seek limited... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Limited exemptions....

  19. 10 CFR 490.308 - Process for granting exemptions.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Process for granting exemptions. 490.308 Section 490.308 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fuel... exemption to the Office of Energy Efficiency and Renewable Energy, U.S. Department of Energy, EE-33,...

  20. 9 CFR 106.1 - Biological products; exemption.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS EXEMPTION FOR BIOLOGICAL PRODUCTS USED IN DEPARTMENT PROGRAMS OR UNDER DEPARTMENT CONTROL OR SUPERVISION § 106.1 Biological products... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Biological products; exemption....

  1. 77 FR 27842 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-05-11

    ... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating..., 2003 (68 FR 52441).\\1\\ The revision must provide for individual assessment of drivers with diabetes... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  2. 12 CFR 26.5 - Small market share exemption.

    Science.gov (United States)

    2010-01-01

    ... Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MANAGEMENT OFFICIAL INTERLOCKS § 26.5 Small market share exemption. (a) Exemption. A management interlock that is prohibited by § 26.3... recent annual Summary of Deposits published by the FDIC for the RMSA or community. (b) Confirmation...

  3. 10 CFR 490.204 - Process for granting exemptions.

    Science.gov (United States)

    2010-01-01

    ... Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Mandatory State Fleet Program § 490.204 Process for granting exemptions. (a) To obtain an exemption, in whole or in part...) Alternative fuels that meet the normal requirements and practices of the principal business of the State...

  4. 78 FR 68137 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-11-13

    ... W. O'Neill (WA) Robert M. Pickett II (MI) John N. Poland (IL) Eligio M. Ramirez (TX) Garry L. Rogers... vision requirement if the exemptions granted will not compromise safety. The Agency has concluded that granting these exemption renewals will provide a level of safety that is equivalent to or greater than...

  5. 32 CFR 505.10 - Use and establishment of exemptions.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Use and establishment of exemptions. 505.10 Section 505.10 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.10 Use and establishment of exemptions....

  6. 28 CFR 16.76 - Exemption of Justice Management Division.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Justice Management Division. 16.76 Section 16.76 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF... Management Division. (a) The following system of records is exempt from 5 U.S.C. 552a(d): (1)...

  7. Tax exemption: why not-for-profits deserve it.

    Science.gov (United States)

    Annis, R; Kistner, W G

    1988-04-01

    Not-for-profit healthcare facilities' tax-exempt status is coming under attack, particularly in congressional hearings on the unrelated business income tax. Therefore tax-exempt providers must keep adequate records of all services and expenditures to demonstrate and preserve their exempt nature. A facility qualifies for tax exemption by demonstrating that it is legally organized to achieve its exempt purpose and that the bulk of its activities is directed toward that goal. The exemption indicates an agreement between the government and the facility: The government is willing to forgo collection of the tax due because the facility performs tasks that would otherwise befall the government, in particular, caring for the indigent. In addition to such care, other social goods flowing from tax-exempt healthcare facilities include their responsiveness to the needs of the nation, their desire to benefit the community, the medical training they provide, and their role as outlets for philanthropy. Before great changes are made in the unrelated business income tax, tax-exempt facilities must make legislatures and the public aware of the vital services they provide. PMID:10286448

  8. 19 CFR 12.104h - Exempt materials and articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Exempt materials and articles. 12.104h Section 12... THE TREASURY SPECIAL CLASSES OF MERCHANDISE Cultural Property § 12.104h Exempt materials and articles... material or any article of cultural property which is imported into the U.S. for temporary exhibition...

  9. 19 CFR 148.46 - Sale of exempted articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Sale of exempted articles. 148.46 Section 148.46... exempted articles. (a) Sale resulting in forfeiture. The following articles or their value (to be recovered... paragraph (b) of this section is followed: (1) Any jewelry or similar articles of personal adornment...

  10. 29 CFR 784.117 - Combinations of exempt work.

    Science.gov (United States)

    2010-07-01

    ... under another section of the Act, is permitted. Where a part of an employee's covered work in a workweek... work exempt from both the minimum wage and overtime requirements under another section of the Act. In... 29 Labor 3 2010-07-01 2010-07-01 false Combinations of exempt work. 784.117 Section 784.117...

  11. 29 CFR 793.21 - Exempt and nonexempt work.

    Science.gov (United States)

    2010-07-01

    ... workweek performs work which is exempt from the overtime requirements of the Act under section 13(b)(9..., performs a substantial amount of nonexempt work to which the overtime provisions of the Act are applicable... 29 Labor 3 2010-07-01 2010-07-01 false Exempt and nonexempt work. 793.21 Section 793.21...

  12. 29 CFR 403.9 - Attorney-client communications exempted.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Attorney-client communications exempted. 403.9 Section 403... LABOR-MANAGEMENT STANDARDS LABOR ORGANIZATION ANNUAL FINANCIAL REPORTS § 403.9 Attorney-client communications exempted. Nothing contained in this part shall be construed to require an attorney who is a...

  13. 29 CFR 402.11 - Attorney-client communications exempted.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Attorney-client communications exempted. 402.11 Section 402... LABOR-MANAGEMENT STANDARDS LABOR ORGANIZATION INFORMATION REPORTS § 402.11 Attorney-client communications exempted. Nothing contained in this part shall be construed to require an attorney who is a...

  14. 29 CFR 404.5 - Attorney-client communications exempted.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Attorney-client communications exempted. 404.5 Section 404... LABOR-MANAGEMENT STANDARDS LABOR ORGANIZATION OFFICER AND EMPLOYEE REPORTS § 404.5 Attorney-client communications exempted. Nothing contained in this part shall be construed to require an attorney who is a...

  15. 46 CFR 502.67 - Exemption procedures-General.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Exemption procedures-General. 502.67 Section 502.67 Shipping FEDERAL MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS RULES OF PRACTICE AND PROCEDURE..., upon application or on its own motion, may by order or rule exempt for the future any class...

  16. 77 FR 2761 - Exemptions From Certain Prohibited Transaction Restrictions

    Science.gov (United States)

    2012-01-19

    ... the R+L Companies are: (1) R+L Carriers Shared Services, LLC; (2) Strategic Management, LLC; (3...) of the Code and the procedures set forth in 29 CFR part 2570, subpart B (55 FR 32836, 32847, August... exemption, refer to the notice of proposed exemption published on September 26, 2011 at 76 FR...

  17. 32 CFR 806.7 - Use of exemptions.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Use of exemptions. 806.7 Section 806.7 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE ADMINISTRATION AIR FORCE FREEDOM OF INFORMATION ACT PROGRAM § 806.7 Use of exemptions. (a) A listing of some AFIs that provide guidance on...

  18. 76 FR 37883 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-06-28

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... receipt of exemption applications from certain individuals, and requested comments from the public (76 FR... discussed in detail in the May 5, 2011 notice (76 FR 25764). Basis for Exemption Determination Under 49...

  19. 77 FR 75494 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-12-20

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... receipt of exemption applications from certain individuals, and requested comments from the public (77 FR... discussed in detail in the October 23, 2012 notice (77 FR 64839). Basis for Exemption Determination Under...

  20. 77 FR 22059 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-04-12

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... receipt of exemption applications from certain individuals, and requested comments from the public (77 FR... February 13, 2012 notice (77 FR 7657). Basis for Exemption Determination Under 49 U.S.C. 31136(e) and...

  1. 78 FR 52602 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-08-23

    ... FR 3316). Background On June 6, 2013, FMCSA published a notice of receipt of exemption applications from certain individuals, and requested comments from the public (78 FR 34143). That notice listed 69... discussed in detail in the June 6, 2013 notice (78 FR 34143). Basis for Exemption Determination Under 49...

  2. 75 FR 28682 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-05-21

    ... Statement in the Federal Register published on April 11, 2000 (65 FR 19476). This information is also... of exemption applications from certain individuals, and requested comments from the public (75 FR... notice (75 FR 14656). Basis for Exemption Determination Under 49 U.S.C. 31136(e) and 31315, FMCSA...

  3. 78 FR 27281 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-05-09

    ... January 17, 2008 (73 FR 3316). FOR FURTHER INFORMATION CONTACT: Elaine M. Papp, Chief, Medical Programs...; Exemption Applications; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION... applications from 25 individuals for exemption from the vision requirement in the Federal Motor Carrier...

  4. 29 CFR 779.385 - May qualify as exempt establishments.

    Science.gov (United States)

    2010-07-01

    ... in clause (B) of the exemption. Typical examples of such are the concessionaires at amusement parks... Establishments Seasonal Amusement Or Recreational Establishments § 779.385 May qualify as exempt establishments. An amusement or recreational establishment operating on a seasonal basis may qualify as an...

  5. 19 CFR 10.17 - Valuation of exempted components.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Valuation of exempted components. 10.17 Section 10.17 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... Assembled Abroad with United States Components § 10.17 Valuation of exempted components. The value...

  6. 21 CFR 801.110 - Retail exemption for prescription devices.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Retail exemption for prescription devices. 801.110 Section 801.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From Adequate Directions for Use § 801.110 Retail...

  7. 21 CFR 201.127 - Drugs; expiration of exemptions.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Drugs; expiration of exemptions. 201.127 Section 201.127 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING Exemptions From Adequate Directions for Use § 201.127 Drugs;...

  8. 77 FR 543 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-01-05

    ... applicants has satisfied the entry conditions for obtaining an exemption from the vision requirements (74 FR 60022; 75 FR 4623). Each of these 17 applicants has requested renewal of the exemption and has submitted... Privacy Act Statement for the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316),...

  9. 75 FR 38864 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-06

    ... 16, 2010 (75 FR 27621). Discussion of Comments FMCSA received no comments in this proceeding...-11714; FMCSA- 2008-0021] Qualification of Drivers; Exemption Renewals; Vision AGENCY: Federal Motor... announced its decision to renew the exemptions from the vision requirement in the Federal Motor...

  10. 75 FR 22179 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-27

    ... comment period ended on April 1, 2010 (75 FR 9477). Discussion of Comments FMCSA received no comments in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in...

  11. 75 FR 22178 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-27

    ... comment period ended on April 1, 2010 (75 FR 9484). Discussion of Comments FMCSA received no comments in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in...

  12. 75 FR 39618 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-09

    ... comment period ended on June 16, 2010 (75 FR 27622). Discussion of Comments FMCSA received no comments in...-24015; FMCSA-2007-0071; FMCSA-2008-0021] Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in...

  13. 75 FR 19676 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-15

    ... period. The comment period ended on March 25, 2010 (75 FR 8184). Discussion of Comments FMCSA received no...-2005-22194; FMCSA-2007-27897] Qualification of Drivers; Exemption Renewals; Vision AGENCY: Federal... previously announced its decision to renew the exemptions from the vision requirement in the Federal...

  14. 75 FR 1453 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-01-11

    ... at the end of the 2-year period. The comment period ended on December 7, 2009 (74 FR 57553...-2007-27897; FMCSA- 2007-28695; FMCSA-2007-29019] Qualification of Drivers; Exemption Renewals; Vision.... SUMMARY: FMCSA previously announced its decision to renew the exemptions from the vision requirement...

  15. Block Curricula: A Guide to Teaching with Unit Blocks and Hollow Blocks in the Classroom.

    Science.gov (United States)

    Clark, Phyllis; Tiedemann, Nancy

    This curriculum guide for preschool teachers was designed for use with wooden unit and hollow blocks to foster a variety of math, science, language, and social skills. Following an introduction to the curriculum and a discussion of cooperative learning and stages of block building, the guide is divided into three parts. Part 1 of the guide, "Unit…

  16. Criminal Justice Systems. Block I: Law Enforcement. Block II: The Courts. Block III: Corrections. Block IV: Community Relations. Block V: Proficiency Skills. Block VI: Criminalistics. Student Guide.

    Science.gov (United States)

    Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

    This student guide together with an instructor guide comprise a set of curriculum materials on the criminal justice system. The student guide contains self-contained instructional material that students can study at their own pace most of the time. Six major subject areas or blocks, which are further broken down into several units, with some units…

  17. Criminal Justice Systems. Block I: Law Enforcement. Block II: The Courts. Block III: Corrections. Block IV: Community Relations. Block V: Proficiency Skills. Block VI: Criminalistics. Instructor Guide.

    Science.gov (United States)

    Florida State Dept. of Education, Tallahassee. Div. of Vocational, Adult, and Community Education.

    This instructor guide together with a student guide comprise a set of curriculum materials on the criminal justice system. The instructor guide is a resource for planning and managing individualized, competency-based instruction in six major subject areas or blocks, which are further broken down into several units with some units having several…

  18. Development of Regulatory Guidance for the Review of Exemption Requests from the Requirements for Licensed Personnel Staffing

    International Nuclear Information System (INIS)

    The introduction of advanced reactor designs and the increased use of advanced automation in existing nuclear power plants will likely change the roles, responsibilities, composition, and size of the crews required to control plant operations. The design features and concepts of operation for new generations of advanced reactors, as well as the introduction of new automated systems into existing plants, may lead to reductions in staff size and a changing role for the operator. Current regulations regarding control room staffing, which are based upon the concept of operation for existing light-water reactors, may no longer apply. Therefore, applicants for an operating license for an advanced reactor, and current licensees who have implemented significant changes to existing control rooms, may submit applications for exemptions from current staffing regulations. The NRC staff will be responsible for reviewing the exemption requests and determining whether the staffing proposals will provide adequate assurance that public health and safety are maintained to a level that is comparable to compliance with the current regulations. This paper discusses the proposed regulatory guidance for the review of requests for exemptions from any of the requirements of 10 CFR Part 50 related to the number of licensed personnel needed to safely operate the nuclear power plant, as well as computerized tools to assist in the review. (authors)

  19. Ambulatory surgery center joint ventures involving tax-exempt entities.

    Science.gov (United States)

    Becker, S; Pristave, R J; McConnell, W

    1999-01-01

    This article provides an overview of the tax-exempt related issues for ambulatory surgery center joint ventures involving tax-exempt entities. The article analyzes the key points of analysis of the guidance released by the IRS, in particular General Counsel Memorandum 39862, Revenue Ruling 98-15, and Redlands Surgical Services v. Commissioner of the Internal Revenue Service. These key points include whether the venture results in private inurement to insiders and whether the venture furthers the charitable purposes of the tax-exempt entity. The article also provides practical guidance to analyze the documents and structure of the joint venture to ensure compliance with the IRS guidance. These practical considerations include, among other things, whether the charitable purposes of the tax-exempt entity are clearly expressed in the documents and whether the tax-exempt entity has sufficient control over the joint venture to ensure the charitable purposes are being adhered to.

  20. 17 CFR 247.775 - Exemption from the definition of “broker” for banks effecting certain excepted or exempted...

    Science.gov (United States)

    2010-04-01

    .... (2) Interdealer quotation system has the same meaning as in 17 CFR 240.15c2-11. (3) Insurance company... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption from the definition of âbrokerâ for banks effecting certain excepted or exempted transactions in investment...

  1. 12 CFR 218.776 - Exemption from the definition of “broker” for banks effecting certain excepted or exempted...

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Exemption from the definition of âbrokerâ for banks effecting certain excepted or exempted transactions in a company's securities for its employee... FEDERAL RESERVE SYSTEM EXCEPTIONS FOR BANKS FROM THE DEFINITION OF BROKER IN THE SECURITIES EXCHANGE...

  2. 12 CFR 218.775 - Exemption from the definition of “broker” for banks effecting certain excepted or exempted...

    Science.gov (United States)

    2010-01-01

    ... system has the same meaning as in 17 CFR 240.15c2-11. (3) Insurance company has the same meaning as in 15... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Exemption from the definition of âbrokerâ for banks effecting certain excepted or exempted transactions in investment company securities....

  3. Block copolymer patterns and templates

    Directory of Open Access Journals (Sweden)

    Mingqi Li

    2006-09-01

    Full Text Available This review describes the chemical and physical aspects of patternable block copolymers and their use for nanostructure fabrication. The patternability of block copolymers results from their ability to self-assemble into microdomains and the manipulation of these patterns by a variety of physical and chemical means. Procedures for achieving long-range lateral order, as well as orientation order of microdomain patterns, are discussed. The level of control that these strategies afford has enabled block copolymers to be used as templates for fabricating a variety of nanostructures.

  4. 75 FR 12296 - Prohibited Transaction Exemptions and Grant of Individual Exemptions Involving: 2010-04, JPMorgan...

    Science.gov (United States)

    2010-03-15

    ... Involving: 2010-04, JPMorgan Chase Bank, N.A. (JPMCB or the Applicants), D-11491; 2010-05, Goldman Sachs... in 29 CFR part 2570, Subpart B (55 FR 32836, 32847, August 10, 1990) and based upon the entire record... Department's decision to grant this exemption, refer to the text of the Notice at 74 FR 58987. FOR...

  5. Recursion Relations for Conformal Blocks

    CERN Document Server

    Penedones, João; Yamazaki, Masahito

    2015-01-01

    In the context of conformal field theories in general space-time dimension, we find all the possible singularities of the conformal blocks as functions of the scaling dimension $\\Delta$ of the exchanged operator. In particular, we argue, using representation theory of parabolic Verma modules, that in odd spacetime dimension the singularities are only simple poles. We discuss how to use this information to write recursion relations that determine the conformal blocks. We first recover the recursion relation introduced in 1307.6856 for conformal blocks of external scalar operators. We then generalize this recursion relation for the conformal blocks associated to the four point function of three scalar and one vector operator. Finally we specialize to the case in which the vector operator is a conserved current.

  6. MarineMineralsProgramBlocks

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains OCS block outlines and delineated polygons in ESRI ArcGIS shape file format for the BOEM Gulf of Mexico Region that contain sediment...

  7. Left bundle-branch block

    DEFF Research Database (Denmark)

    Risum, Niels; Strauss, David; Sogaard, Peter;

    2013-01-01

    The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a fundamental understanding of physiology have recently...

  8. A Novel Tetrathiafulvalene Building Block

    DEFF Research Database (Denmark)

    Jeppesen, Jan Oskar; Takimiya, Kazuo; Thorup, Niels;

    1999-01-01

    Efficient synthesis of a novel tetrathiafulvalene building block. 2,3-bis(2-cyanoethylthio)-6,7-bis(thiocyanato-methyl)tetrathiafulv alene (7) useful for stepwise and asymmetrical bis-function-alization is reported.......Efficient synthesis of a novel tetrathiafulvalene building block. 2,3-bis(2-cyanoethylthio)-6,7-bis(thiocyanato-methyl)tetrathiafulv alene (7) useful for stepwise and asymmetrical bis-function-alization is reported....

  9. Statistical cryptanalysis of block ciphers

    OpenAIRE

    Junod, Pascal; Vaudenay, Serge

    2007-01-01

    Since the development of cryptology in the industrial and academic worlds in the seventies, public knowledge and expertise have grown in a tremendous way, notably because of the increasing, nowadays almost ubiquitous, presence of electronic communication means in our lives. Block ciphers are inevitable building blocks of the security of various electronic systems. Recently, many advances have been published in the field of public-key cryptography, being in the understanding of involved securi...

  10. NANOSTRUCTURES OF FUNCTIONAL BLOCK COPOLYMERS

    Institute of Scientific and Technical Information of China (English)

    Guojun Liu

    2000-01-01

    Nanostructure fabrication from block copolymers in my group normally involves polymer design, synthesis, selfassembly, selective domain crosslinking, and sometimes selective domain removal. Preparation of thin films with nanochannels was used to illustrate the strategy we took. In this particular case, a linear triblock copolymer polyisopreneblock-poly(2-cinnamoylethyl methacrylate)-block-poly(t-butyl acrylate), PI-b-PCEMA-b-PtBA, was used. Films, 25 to50μm thick, were prepared from casting on glass slides a toluene solution of PI-b-PCEMA-b-PtBA and PtBA homopolymer,hPtBA, where hPtBA is shorter than the PtBA block. At the hPtBA mass fraction of 20% relative to the triblock or the total PtBA (hPtBA and PtBA block) volume fraction of 0.44, hPtBA and PtBA formed a seemingly continuous phase in the matrix of PCEMA and PI. Such a block segregation pattern was locked in by photocrosslinking the PCEMA domain. Nanochannels were formed by extracting out hPtBA with solvent. Alternatively, larger channels were obtained from extracting out hPtBA and hydrolyzing the t-butyl groups of the PtBA block. Such membranes were not liquid permeable but had gas permeability constants ~6 orders of magnitude higher than that of low-density polyethylene films.

  11. MORINGA TEA BLOCKS ACUTE LUNG INFLAMMATION INDUCED BY SWINE CONFINEMENT DUST THROUGH A MECHANISM INVOLVING TNF-α EXPRESSION, C-JUN N-TERMINAL KINASE ACTIVATION AND NEUTROPHIL REGULATION

    Directory of Open Access Journals (Sweden)

    Mykea Mcknight

    2014-01-01

    Full Text Available Plant based products represent a promising alternative to conventional treatments for inflammation. Moringa oleifera Lam is a tree rich in proteins, vitamins, minerals and a variety of phytochemcals with health benefits. Among the reported health benefits are antioxidant and anti-inflammatory properties. The purpose of this study was to investigate whether tea brewed from dried Moringa leaves would abrogate inflammation in a mouse model of acute lung inflammation induced by LPS or extracts prepared from dust collected from a swine confinement facility (DE. Mice were offered water or Moringa tea for seven days. Tea consumption was significantly greater than that of water consumption on days 1 and 6, but there were no significant differences in weight gain or food consumption. On day seven, mice from both groups were forced to inhale, via intranasal challenge, either Phosphate Buffered Saline (PBS, Lipopolysaccharide (LPS [10 µg mL-1] or DE [10%]. Compared to mice that drank water, mice that drank Moringa tea had significantly less protein (p<0.05 and cellular influx (p<0.0001 into the lung after inhalation of 10% DE. No difference in neutrophil migration into the lungs of water and M. tea groups after LPS or DE challenge was detected. But mice that drank tea had significantly (p<0.05 more neutrophils with apoptotic morphology after DE challenge. TNF-α expression 24 h after inhalation of 10% DE, was significantly higher (p<0.05 in lungs of M. tea mouse group as compared to water group. This increase in TNF-α was accompanied by higher levels of pro and anti-inflammatory cytokines. Finally, activation of c-Jun N-terminal Kinase (JNK in lungs of M. tea+DE group 24 h post inhalation was decreased. Taken together these results suggest that Moringa oleifera leaf tea exerts anti-inflammatory properties on acute lung inflammation induced by swine confinement dust through a mechanism involving neutrophil regulation and JNK

  12. 45 CFR 87.2 - Formula and block grants.

    Science.gov (United States)

    2010-10-01

    ... the Charitable Choice regulations found at 42 CFR Part 54 and 45 CFR Parts 96, 260, and 1050. (b... CFR Parts 74, 92, and 96. (c) Organizations that receive direct financial assistance from the... 45 Public Welfare 1 2010-10-01 2010-10-01 false Formula and block grants. 87.2 Section 87.2...

  13. 31 CFR 544.201 - Prohibited transactions involving blocked property.

    Science.gov (United States)

    2010-07-01

    ... DESTRUCTION PROLIFERATORS SANCTIONS REGULATIONS Prohibitions § 544.201 Prohibited transactions involving... General, and other relevant agencies, to be owned or controlled by, or acting or purporting to act for or... Designated Nationals and Blocked Persons List (“SDN” list) (which is accessible via the Office of...

  14. 31 CFR 546.201 - Prohibited transactions involving blocked property.

    Science.gov (United States)

    2010-07-01

    ... REGULATIONS Prohibitions § 546.201 Prohibited transactions involving blocked property. (a) Except as... be owned or controlled by, or acting or purporting to act for or on behalf of, directly or indirectly... section, are published on the Office of Foreign Assets Control's Specially Designated Nationals...

  15. 31 CFR 543.201 - Prohibited transactions involving blocked property.

    Science.gov (United States)

    2010-07-01

    ... REGULATIONS Prohibitions § 543.201 Prohibited transactions involving blocked property. (a) Except as..., after consultation with the Secretary of State: (i) To constitute a threat to the peace and national... or controlled by, or acting or purporting to act for or on behalf of, directly or indirectly,...

  16. 31 CFR 594.201 - Prohibited transactions involving blocked property.

    Science.gov (United States)

    2010-07-01

    ... support of: (A) Acts of terrorism that threaten the security of U.S. nationals or the national security... SANCTIONS REGULATIONS Prohibitions § 594.201 Prohibited transactions involving blocked property. (a) Except... Attorney General, to have committed, or to pose a significant risk of committing, acts of terrorism...

  17. Skin delivery by block copolymer nanoparticles (block copolymer micelles).

    Science.gov (United States)

    Laredj-Bourezg, Faiza; Bolzinger, Marie-Alexandrine; Pelletier, Jocelyne; Valour, Jean-Pierre; Rovère, Marie-Rose; Smatti, Batoule; Chevalier, Yves

    2015-12-30

    Block copolymer nanoparticles often referred to as "block copolymer micelles" have been assessed as carriers for skin delivery of hydrophobic drugs. Such carriers are based on organic biocompatible and biodegradable materials loaded with hydrophobic drugs: poly(lactide)-block-poly(ethylene glycol) copolymer (PLA-b-PEG) nanoparticles that have a solid hydrophobic core made of glassy poly(d,l-lactide), and poly(caprolactone)-block-poly(ethylene glycol) copolymer (PCL-b-PEG) nanoparticles having a liquid core of polycaprolactone. In vitro skin absorption of all-trans retinol showed a large accumulation of retinol in stratum corneum from both block copolymer nanoparticles, higher by a factor 20 than Polysorbate 80 surfactant micelles and by a factor 80 than oil solution. Additionally, skin absorption from PLA-b-PEG nanoparticles was higher by one order of magnitude than PCL-b-PEG, although their sizes (65nm) and external surface (water-swollen PEG layer) were identical as revealed by detailed structural characterizations. Fluorescence microscopy of histological skin sections provided a non-destructive picture of the storage of Nile Red inside stratum corneum, epidermis and dermis. Though particle cores had a different physical states (solid or liquid as measured by (1)H NMR), the ability of nanoparticles for solubilization of the drug assessed from their Hildebrand solubility parameters appeared the parameter of best relevance regarding skin absorption.

  18. Application of Generic Exemption Levels for Radioactive Material

    International Nuclear Information System (INIS)

    In essence, exemption is an authorization granted by the regulatory body, which, once issued, releases the user of the radioactive source from the requirements that would otherwise apply, in particular, the requirements relating to notification and authorization. The exemption figures included in the Basic Safety Standards BSS 115 were derived from scenarios postulated in the document 'Radiation Protection 65' of the Commission of the European Communities considering quantitative exemption criteria. This paper briefly describes and analyses these scenarios and also, describes the status of an implementation guide of these levels in the Argentinean Regulatory System. (authors)

  19. Block Matching for Object Tracking

    Energy Technology Data Exchange (ETDEWEB)

    Gyaourova, A; Kamath, C; Cheung, S

    2003-10-13

    Models which describe road traffic patterns can be helpful in detection and/or prevention of uncommon and dangerous situations. Such models can be built by the use of motion detection algorithms applied to video data. Block matching is a standard technique for encoding motion in video compression algorithms. We explored the capabilities of the block matching algorithm when applied for object tracking. The goal of our experiments is two-fold: (1) to explore the abilities of the block matching algorithm on low resolution and low frame rate video and (2) to improve the motion detection performance by the use of different search techniques during the process of block matching. Our experiments showed that the block matching algorithm yields good object tracking results and can be used with high success on low resolution and low frame rate video data. We observed that different searching methods have small effect on the final results. In addition, we proposed a technique based on frame history, which successfully overcame false motion caused by small camera movements.

  20. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Science.gov (United States)

    2010-10-18

    ... Federal Register, 73 FR 25594, May 7, 2008. The proposed amendments: (1) Waived all copying fees in..., 73 FR 54595, September 22, 2008, certain portions of BGFRS-37 (Electronic Applications) may be exempt... CFR Part 261a Privacy Act of 1974; Privacy Act Regulation AGENCY: Board of Governors of the...

  1. Some aspects in the compliance with the Japanese radiation protection regulations

    International Nuclear Information System (INIS)

    This paper gives an overview of the major subjects in the recent amendments to the Japanese radiation protection regulations. These are related to the scope of the application of regulations: exclusion, exemption and clearance. The Radiological Hazards Prevention Law has modified the legal definition of 'radioactive materials'. The Reactors Control Law has been amended to establish clearance levels for releasing radioactive materials from regulatory control. The Japanese government has a plan to develop guidelines for exclusion and exemption of certain types of naturally-occurring radioactive materials (NORM). Some aspects in the compliance with the regulations are addressed. (author)

  2. Free-riding, fairness and the rights of minority groups in exemption from mandatory childhood vaccination.

    Science.gov (United States)

    May, Thomas; Silverman, Ross D

    2005-01-01

    The authority of government to require participation in mandatory childhood vaccination programs may not target specific groups for either participation or exemption on a discriminatory basis. This poses difficulties when allowing religious or philosophical exemptions to mandatory vaccination, because certain groups are more likely to appeal for exemption. Avoiding loss of herd immunity, then, may require either discrimination against these groups by disallowing an exemption option that is available to others, or by denying the good of an exemption option to the entire population because of the action of certain groups. To avoid this unacceptable choice, steps must be taken now to more stringently enforce exemption requirements.

  3. Climatological features of blocking anticyclones

    International Nuclear Information System (INIS)

    Several climatological studies have been previously performed using large observational data sets (i.e., 10 years or longer) in order to determine the predominant characteristics of blocking anticyclones, including favored development regions, duration, preferred seasonal occurrence, and frequency of occurrence. These studies have shown that blocking anticyclones occur most frequently from October to April over the eastern Atlantic and Pacific oceans downstream from both the North American and Asian continental regions and the storm track regions to the east of these continents. Some studies have also revealed the presence of a third region block formation in western Russia near 40 degrees E which is associated with another storm track region over the Mediterranean and western Asia

  4. Projectors, Shadows, and Conformal Blocks

    CERN Document Server

    Simmons-Duffin, David

    2012-01-01

    We introduce a method for computing conformal blocks of operators in arbitrary Lorentz representations in any spacetime dimension, making it possible to apply bootstrap techniques to operators with spin. The key idea is to implement the "shadow formalism" of Ferrara, Gatto, Grillo, and Parisi in a setting where conformal invariance is manifest. Conformal blocks in d-dimensions can be expressed as integrals over the projective null-cone in the "embedding space" R^{d+1,1}. Taking care with their analytic structure, these integrals can be evaluated in great generality, reducing the computation of conformal blocks to a bookkeeping exercise. To facilitate calculations in four-dimensional CFTs, we introduce techniques for writing down conformally-invariant correlators using auxiliary twistor variables, and demonstrate their use in some simple examples.

  5. Regulated control of practices and radiation sources

    International Nuclear Information System (INIS)

    Excepting the radiation caused by the natural background radiation, the Executive Secretariat for Nuclear Affairs (SEAN) does not authorize any source no practice within the national territory that may imply exposure of a person to ionizing radiation unless this use is ruled. This document establishes the basic criteria to set up such system as well as to exclude or exempt practices and sources from this regulated control

  6. Block ground interaction of rockfalls

    Science.gov (United States)

    Volkwein, Axel; Gerber, Werner; Kummer, Peter

    2016-04-01

    During a rockfall the interaction of the falling block with the ground is one of the most important factors that define the evolution of a rockfall trajectory. It steers the rebound, the rotational movement, possibly brake effects, friction losses and damping effects. Therefore, if most reliable rockfall /trajectory simulation software is sought a good understanding of the block ground interaction is necessary. Today's rockfall codes enable the simulation of a fully 3D modelled block within a full 3D surface . However, the details during the contact, i.e. the contact duration, the penetration depth or the dimension of the marks in the ground are usually not part of the simulation. Recent field tests with rocks between 20 and 80 kg have been conducted on a grassy slope in 2014 [1]. A special rockfall sensor [2] within the blocks measured the rotational velocity and the acting accelerations during the tests. External video records and a so-called LocalPositioningSystem deliver information on the travel velocity. With these data not only the flight phases of the trajectories but also the contacts with the ground can be analysed. During the single jumps of a block the flight time, jump length, the velocity, and the rotation are known. During the single impacts their duration and the acting accelerations are visible. Further, the changes of rotational and translational velocity influence the next jump of the block. The change of the rotational velocity over the whole trajectory nicely visualizes the different phases of a rockfall regarding general acceleration and deceleration in respect to the inclination and the topography of the field. References: [1] Volkwein A, Krummenacher B, Gerber W, Lardon J, Gees F, Brügger L, Ott T (2015) Repeated controlled rockfall trajectory testing. [Abstract] Geophys. Res. Abstr. 17: EGU2015-9779. [2] Volkwein A, Klette J (2014) Semi-Automatic Determination of Rockfall Trajectories. Sensors 14: 18187-18210.

  7. OPAL 96 Blocks Lead Glass

    CERN Multimedia

    This array of 96 lead glass bricks formed part of the OPAL electromagnetic calorimeter. One half of the complete calorimeter is shown in the picture above. There were 9440 lead glass counters in the OPAL electromagnetic calorimeter. These are made of Schott type SF57 glass and each block weighs about 25 kg and consists of 76% PbO by weight. Each block has a Hamamatsu R2238 photomultiplier glued on to it. The complete detector was in the form of a cylinder 7m long and 6m in diameter. It was used to measure the energy of electrons and photons produced in LEP interactions.

  8. 7 CFR 504.4 - Exemptions from user fee charges.

    Science.gov (United States)

    2010-01-01

    ... cooperators designated by the Curator of the ARS Patent Culture Collection are exempt from fee assessments. (b) The Curator of the ARS Patent Culture Collection is delegated the authority to approve and...

  9. 77 FR 33551 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-06

    ... prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  10. 21 CFR 1310.12 - Exempt chemical mixtures.

    Science.gov (United States)

    2010-04-01

    ... safrole. Methylamine and its salts 8520 20% by Weight Methylamine or its salts in an inert carrier solvent... otherwise exempted. Safrole 8323 20% by Volume Concentration in a mixture cannot exceed 20% if taken...

  11. 21 CFR 1316.24 - Exemption from prosecution for researchers.

    Science.gov (United States)

    2010-04-01

    ... of the Drug Enforcement Administration, on his own motion or upon request in writing from the... afforded by the grant of exemption from prosecution during the research period shall be perpetual....

  12. 75 FR 80889 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-12-23

    ...; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate...

  13. 78 FR 78479 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-26

    ... prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  14. 77 FR 18302 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-27

    ... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... for individual assessment of drivers with diabetes mellitus, and be consistent with the...

  15. 76 FR 17475 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-03-29

    ... for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... for individual assessment of drivers with diabetes mellitus, and be consistent with the...

  16. 76 FR 55460 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-09-07

    ...; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate...

  17. 77 FR 64181 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-18

    ...; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA... with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in...

  18. 76 FR 66637 - Prohibited Transaction Exemption Procedures; Employee Benefit Plans

    Science.gov (United States)

    2011-10-27

    ...; Employee Benefit Plans AGENCY: Employee Benefits Security Administration, Labor. ACTION: Final rule... FURTHER INFORMATION CONTACT: Eric A. Raps, Office of Exemption Determinations, Employee Benefits Security... relating to employee benefit plans, or provisions of FERSA relating to the Federal Thrift Savings...

  19. 31 CFR 515.528 - Certain transactions with respect to blocked foreign intellectual property.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Certain transactions with respect to blocked foreign intellectual property. 515.528 Section 515.528 Money and Finance: Treasury Regulations... Certain transactions with respect to blocked foreign intellectual property. (a) The following...

  20. 33 CFR 110.150 - Block Island Sound, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Block Island Sound, N.Y. 110.150 Section 110.150 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.150 Block Island Sound, N.Y. (a) The anchorage ground. A...

  1. 24 CFR Appendix A to Part 1000 - Indian Housing Block Grant Formula Mechanics

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Indian Housing Block Grant Formula Mechanics A Appendix A to Part 1000 Housing and Urban Development Regulations Relating to Housing and Urban... Housing Block Grant Formula Mechanics This appendix shows the different components of the IHBG...

  2. Planning Block Play Experiences for Young Children.

    Science.gov (United States)

    Baker, Betty Ruth

    Playing with blocks can facilitate the creative, social, emotional, physical, and cognitive development of young children. This article presents information and activities concerning block play and its role in young children's experience. Topics covered include: (1) types of blocks; (2) selection of blocks and accessories; (3) planning of the…

  3. 26 CFR 1.852-2 - Method of taxation of regulated investment companies.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Method of taxation of regulated investment... Trusts § 1.852-2 Method of taxation of regulated investment companies. (a) Imposition of normal tax and... for partially tax-exempt interest provided by section 242. (b) Taxation of capital gains—(1)...

  4. First Degree Pacemaker Exit Block

    Directory of Open Access Journals (Sweden)

    Johnson Francis

    2016-10-01

    Full Text Available Usually atrial and ventricular depolarizations follow soon after the pacemaker stimulus (spike on the ECG. But there can be an exit block due to fibrosis at the electrode - tissue interface at the lead tip. This can increase the delay between the spike and atrial or ventricular depolarization.

  5. Building Blocks for Personal Brands

    Science.gov (United States)

    Thomas, Lisa Carlucci

    2011-01-01

    In this article, the author discusses the four essential building blocks for personal brands: (1) name; (2) message; (3) channels; and (4) bridges. However, outstanding building materials can only take a person so far. The author emphasizes that vision, determination, faith, a sense of humor, and humility are also required.

  6. Scattering matrices with block symmetries

    OpenAIRE

    Życzkowski, Karol

    1997-01-01

    Scattering matrices with block symmetry, which corresponds to scattering process on cavities with geometrical symmetry, are analyzed. The distribution of transmission coefficient is computed for different number of channels in the case of a system with or without the time reversal invariance. An interpolating formula for the case of gradual time reversal symmetry breaking is proposed.

  7. Building block filtering and mixing

    NARCIS (Netherlands)

    Kemenade, C.H.M. van

    1998-01-01

    A three-stage evolutionary method, the BBF-GA is introduced. BBF-GA is an acronym for building block filtering genetic algorithm. During the first stage, an ensemble of fast evolutionary algorithms is used to explore the search space. The best individual found by each of these evolutionary algorithm

  8. Preschoolers' Thinking during Block Play

    Science.gov (United States)

    Piccolo, Diana L.; Test, Joan

    2010-01-01

    Children build foundations for mathematical thinking in early play and exploration. During the preschool years, children enjoy exploring mathematical concepts--such as patterns, shape, spatial relationships, and measurement--leading them to spontaneously engage in mathematical thinking during play. Block play is one common example that engages…

  9. Pourfour Du Petit syndrome after interscalene block

    Directory of Open Access Journals (Sweden)

    Mysore Chandramouli Basappji Santhosh

    2013-01-01

    Full Text Available Interscalene block is commonly associated with reversible ipsilateral phrenic nerve block, recurrent laryngeal nerve block, and cervical sympathetic plexus block, presenting as Horner′s syndrome. We report a very rare Pourfour Du Petit syndrome which has a clinical presentation opposite to that of Horner′s syndrome in a 24-year-old male who was given interscalene block for open reduction and internal fixation of fracture upper third shaft of left humerus.

  10. Innovative masonry blocks for partition walls

    OpenAIRE

    Vasconcelos, Graça; Poletti, Elisa; Medeiros, Pedro; Mendonça, Paulo; Carvalho, Pedro; Cunha, Sandra Raquel Leite; Camões, Aires; Lourenço, Paulo B.

    2010-01-01

    This paper intends to propose a non structural system of partition walls with monolithic blocks based on a composite material resulting from an admixture of cork and textile fibers combined with a non cement binder, gypsum. These blocks consist of two half blocks which have to be connected during laying process. The developed blocks were first tested under compressive and flexural loading in order to derive their mechanical behaviour. Different curing conditions were applied to the blocks dur...

  11. Block Algorithms for Quark Propagator Calculation

    CERN Document Server

    Pickles, S M

    1998-01-01

    Computing quark propagators in lattice QCD is equivalent to solving large, sparse linear systems with multiple right-hand sides. Block algorithms attempt to accelerate the convergence of iterative Krylov-subspace methods by solving the multiple systems simultaneously. This paper compares a block generalisation of the quasi-minimal residual method (QMR), Block Conjugate Gradient on the normal equation, Block Lanczos and ($\\gamma_5$-symmetric) Block BiConjugate Gradient.

  12. Endoscopic sphenopalatine ganglion block for pain relief

    OpenAIRE

    Murty, P. S. N.; Prasanna, Atma

    1998-01-01

    The anaesthetic effect of the sphenopalatine (SPG) block has been well utilized for intranasal topical anaesthesia but the analgesic efficacy of (SPG) block, though well documented in literature, has not been put into practice. The methods available for SPG block till date were blind as they do not visualize the foramen. Nasal endoscopies have been used to visualize the foramen for an effective block. The authors present their experience with the endoscopic sphenopalatine ganglion block for p...

  13. Block Algorithms for Quark Propagator Calculation

    OpenAIRE

    Pickles, Stephen M.; Collaboration, UKQCD

    1997-01-01

    Computing quark propagators in lattice QCD is equivalent to solving large, sparse linear systems with multiple right-hand sides. Block algorithms attempt to accelerate the convergence of iterative Krylov-subspace methods by solving the multiple systems simultaneously. This paper compares a block generalisation of the quasi-minimal residual method (QMR), Block Conjugate Gradient on the normal equation, Block Lanczos and ($\\gamma_5$-symmetric) Block BiConjugate Gradient.

  14. Limiting Spectral Distribution of Block Matrices with Toeplitz Block Structure

    CERN Document Server

    Basu, Riddhipratim; Ganguly, Shirshendu; Hazra, Rajat Subhra

    2011-01-01

    We study two specific symmetric random block Toeplitz (of dimension $k \\times k$) matrices: where the blocks (of size $n \\times n$) are (i) matrices with i.i.d. entries, and (ii) asymmetric Toeplitz matrices. Under suitable assumptions on the entries, their limiting spectral distributions (LSDs) exist (after scaling by $\\sqrt{nk}$) when (a) $k$ is fixed and $n \\to\\infty$ (b) $n$ is fixed and $k\\rightarrow \\infty$ (c) $n$ and $k$ go to $\\infty$ simultaneously. Further the LSD's obtained in (a) and (b) coincide with those in (c) when $n$ or respectively $k$ tends to infinity. This limit in (c) is the semicircle law in case (i). In Case (ii) the limit is related to the limit of the random symmetric Toepiltz matrix as obtained by Bryc et al.(2006) and Hammond and Miller(2005).

  15. Cutaneous Sensory Block Area, Muscle-Relaxing Effect, and Block Duration of the Transversus Abdominis Plane Block

    DEFF Research Database (Denmark)

    Støving, Kion; Rothe, Christian; Rosenstock, Charlotte V;

    2015-01-01

    BACKGROUND AND OBJECTIVES: The transversus abdominis plane (TAP) block is a widely used nerve block. However, basic block characteristics are poorly described. The purpose of this study was to assess the cutaneous sensory block area, muscle-relaxing effect, and block duration. METHODS: Sixteen...... healthy volunteers were randomized to receive an ultrasound-guided unilateral TAP block with 20 mL 7.5 mg/mL ropivacaine and placebo on the contralateral side. Measurements were performed at baseline and 90 minutes after performing the block. Cutaneous sensory block area was mapped and separated into a...... medial and lateral part by a vertical line through the anterior superior iliac spine. We measured muscle thickness of the 3 lateral abdominal muscle layers with ultrasound in the relaxed state and during maximal voluntary muscle contraction. The volunteers reported the duration of the sensory block and...

  16. 40 CFR 180.1049 - Carbon dioxide; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... insecticide carbon dioxide is exempted from the requirement of a tolerance when used after harvest in modified atmospheres for stored insect control on food commodities....

  17. 77 FR 8860 - Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations

    Science.gov (United States)

    2012-02-15

    ... exemptions under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) for use of pesticides as... AGENCY Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations... Leader, Emergency Response Team, Registration Division (7505P), Office of Pesticide...

  18. 40 CFR 180.1041 - Nosema locustae; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... insecticide Nosema locustae is exempted from the requirement of a tolerance for residues in or on all...

  19. 40 CFR 180.1050 - Nitrogen; exemption from the requirements of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... insecticide nitrogen is exempted from the requirements of a tolerance when used after harvest in modified atmospheres for stored product insect control on all food commodities....

  20. 76 FR 1602 - Proposed Information Collection; Comment Request; Scientific Research, Exempted Fishing, and...

    Science.gov (United States)

    2011-01-11

    ...; Scientific Research, Exempted Fishing, and Exempted Activity Submissions AGENCY: National Oceanic and... Fishing Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment... necessary for the collection of Highly Migratory Species (HMS) for public display and scientific...