WorldWideScience

Sample records for block exemption regulation

  1. The Influence of the Chicago School on the Commission's Guidelines, Notices and Block Exemption Regulations in EU Competition Policy

    DEFF Research Database (Denmark)

    Bartalevich, Dzmitry

    2016-01-01

    Antitrust rules are fundamentally informed and shaped by economic theories. Given the significance of EU competition policy for the European integration process, it is essential to disentangle the economic theories underlying EU competition law. There is abundant theoretical and empirical...... literature examining the influence of ordoliberalism on EC/EU competition policy. However, in recent years, ordoliberal principles appear to have been replaced by neoliberalism and efficiency-enhancing rationale in EU competition policy. This article puts forward the idea of clarifying whether the European...... Commission incorporates Chicago School theory into EU competition law provisions. The analysis is carried out on the basis of the European Commission's guidelines, notices and block exemption regulations. The analysis reveals that the Commission does, to a considerable extent, follow the Chicago School...

  2. 75 FR 67970 - Notice of Inquiry; An Analysis of the European Union Repeal of the Liner Conference Block Exemption

    Science.gov (United States)

    2010-11-04

    ... European Union's (``E.U.'') repeal of the liner block exemption from competition laws that took effect on... European Union of Regulation 1419/2006 (``Repeal''), on September 25, 2006, removed the previous block... 2006 (when the European Union announced its decision to terminate the block exemption for...

  3. 7 CFR 906.120 - Fruit exempt from regulations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Fruit exempt from regulations. 906.120 Section 906.120 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... grown in the production area are mixed with other types of fruit; (ii) Such oranges and/or...

  4. 75 FR 66686 - Defense Federal Acquisition Regulation Supplement; Balance of Payments Program Exemption for...

    Science.gov (United States)

    2010-10-29

    ... Regulation Supplement; Balance of Payments Program Exemption for Commercial Information Technology... Acquisition Regulation Supplement (DFARS) to implement the exemption from the Balance of Payments Program for... is amending the DFARS to implement in the clauses at 252.225- 7044, Balance of Payments...

  5. 78 FR 70191 - Post-Employment Conflict of Interest Regulations; Exempted Senior Employee Positions; Withdrawal...

    Science.gov (United States)

    2013-11-25

    ... From the Federal Register Online via the Government Publishing Office #0; #0;Rules and Regulations... / Monday, November 25, 2013 / Rules and Regulations#0;#0; ] OFFICE OF GOVERNMENT ETHICS 5 CFR Part 2641 RIN... Regulations; Exempted Senior Employee Positions'' published October 3, 2013, at 78 FR 61153. DATES:...

  6. 78 FR 78424 - Order Granting a Limited Exemption From Rule 102(a) of Regulation M to Certain Business...

    Science.gov (United States)

    2013-12-26

    ... COMMISSION Order Granting a Limited Exemption From Rule 102(a) of Regulation M to Certain Business Development Companies Pursuant to Rule 102(e) of Regulation M December 19, 2013. By letter dated December 19... Commission (``Commission'') issue an exemption from Rule 102 of Regulation M.\\2\\ Specifically, the...

  7. 78 FR 12109 - Order Extending Temporary Exemptions From Certain Rules of Regulation SHO Related to Hurricane Sandy

    Science.gov (United States)

    2013-02-21

    ... seq. \\2\\ Order Granting Exemptions from Certain Rules of Regulation SHO Related to Hurricane Sandy... Hurricane Sandy made landfall and whose settlement depends on the delivery of such physical certificates (or... COMMISSION Order Extending Temporary Exemptions From Certain Rules of Regulation SHO Related to...

  8. 7 CFR 987.152 - Exemption from regulations.

    Science.gov (United States)

    2010-01-01

    ... sell only dates of DAC date quality of the producer's own production in direct sales; and to report such sales to the Committee. If the producer fails to comply with this agreement, the Committee may revoke any or all exemptions granted the producer. (b) Handler exemptions—(1) Specialty sales....

  9. 76 FR 31415 - Federal Acquisition Regulation; Buy American Exemption for Commercial Information Technology...

    Science.gov (United States)

    2011-05-31

    ... 9000-AL62 Federal Acquisition Regulation; Buy American Exemption for Commercial Information Technology... from the Buy American Act for acquisition of information technology that is a commercial item. DATES...., because the rule simplifies the treatment of construction material that is also a commercial...

  10. 75 FR 60266 - Federal Acquisition Regulation; Buy American Exemption for Commercial Information Technology...

    Science.gov (United States)

    2010-09-29

    ... Regulation; Buy American Exemption for Commercial Information Technology--Construction Material AGENCIES... Act for acquisition of information technology that is a commercial item. DATES: Effective Date... the Buy American Act for acquisition of information technology that is a commercial item. This...

  11. 78 FR 79286 - Truth in Lending (Regulation Z): Adjustment to Asset-Size Exemption Threshold

    Science.gov (United States)

    2013-12-30

    ... PROTECTION 12 CFR Part 1026 Truth in Lending (Regulation Z): Adjustment to Asset-Size Exemption Threshold... (Truth in Lending) to reflect a change in the asset size threshold for certain creditors to qualify for... requirements, Savings associations, Truth in lending. Authority and Issuance For the reasons set forth in...

  12. 78 FR 40940 - Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles

    Science.gov (United States)

    2013-07-09

    ... Animal and Plant Health Inspection Service 7 CFR Part 357 RIN 0579-AD11 Lacey Act Implementation Plan; Definitions for Exempt and Regulated Articles AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... and are threatened with extinction); and (iii) plants that are to remain planted or to be planted...

  13. 77 FR 74891 - Order Granting Exemptions From Certain Rules of Regulation SHO Related to Hurricane Sandy

    Science.gov (United States)

    2012-12-18

    ... COMMISSION Order Granting Exemptions From Certain Rules of Regulation SHO Related to Hurricane Sandy December 12, 2012. I. Introduction Hurricane Sandy made landfall along the mid-Atlantic Coast on October 29... in the Vault at the time Hurricane Sandy made landfall, facilitating DTCC's ability to...

  14. Research exemption/experimental use in the European Union: patents do not block the progress of science.

    Science.gov (United States)

    Jaenichen, Hans-Rainer; Pitz, Johann

    2014-11-06

    In the public debate about patents, specifically in the area of biotechnology, the position has been taken that patents block the progress of science. As we demonstrate in this review, this is not the case in the European Union (EU). The national patent acts of the EU member states define research and experimental use exemptions from patent infringement that allow sufficient room for research activities to promote innovation. This review provides a comparative overview of the legal requirements and the extent and limitations of experimental use exemptions, including the so-called Bolar provision, in Germany, the United Kingdom, France, Spain, Italy, and The Netherlands. The legal framework in the respective countries is illustrated with reference to practical examples concerning tests on patent-protected genetic targets and antibodies. Specific questions concerning the use of patent-protected research tools, the outsourcing of research activities, and the use of preparatory and supplying acts for experimental purposes that are necessary for conducting experiments are covered.

  15. Rationing health protection: a proposal to exempt nuisance dust from US Clean Air Act regulations.

    Science.gov (United States)

    Centner, Terence J; Colson, Gregory

    2013-03-15

    The US House of Representative has passed a bill called the "Farm Dust Regulation Prevention Act" (Dust Act) that would exempt most types of particulate matter (PM) in rural areas from the air quality controls of the US Clean Air Act. The Dust Act would markedly change the country's air quality standards. An examination of the proposed provisions shows that they would exempt non-combustion PM pollutants from mining, smelting, petroleum production, and power generation from existing air quality standards. Persons downwind from pollutants generated in rural areas could be exposed to concentrations of carcinogenic heavy metals, asbestos, and benzene known to adversely affect their health and ecological resources. Existing federal air quality standards based on science would be replaced by a flexible standard that rations health protection.

  16. Advanced Therapy Medicinal Products (ATMPand exemptions to the Regulation 1394/2007: how confident can we be? An exploratory analysis.

    Directory of Open Access Journals (Sweden)

    Philippe eVan Wilder

    2012-02-01

    Full Text Available The market authorisation procedure for medicinal products for human use is relying on their demonstrated efficacy, safety and pharmaceutical quality. This applies to all medicinal products whether of chemical or biological origin. Since October 2009, the first advanced therapy medicinal product (ATMP has been authorised through the centralized procedure. ATMPs are gene therapy medicinal products, somatic cell therapy medicinal products or tissue-engineered products.An appropriate ATMP- Regulation is dealing with ATMP requirements.Two exemptions are foreseen to the ATMP-Regulation: a. Products, which were legally on the Community market when the Regulation became applicable, should comply to the Regulation by 30 December 2012. b.the hospital exemption rule for non routine products for an individual patient. In this work we explored whether the actual application of the Regulation on ATMPs is in line with the aim of the Regulation in terms of guaranteeing the highest level of health protection for patients. Based on the analysis of the relative efficacy of the only EC authorized ATMP and its exempted alternatives, there is evidence against this Regulation 1394/2007 assumption.

  17. Advanced Therapy Medicinal Products and Exemptions to the Regulation 1394/2007: How Confident Can We be? An Exploratory Analysis.

    Science.gov (United States)

    Van Wilder, Philippe

    2012-01-01

    The market authorization procedure for medicinal products for human use is relying on their demonstrated efficacy, safety, and pharmaceutical quality. This applies to all medicinal products whether of chemical or biological origin. Since October 2009, the first advanced therapy medicinal product (ATMP) has been authorized through the centralized procedure. ATMPs are gene therapy medicinal products, somatic cell therapy medicinal products or tissue-engineered products. An appropriate ATMP - Regulation is dealing with ATMP requirements. Two exemptions are foreseen to the ATMP Regulation: (a) Products, which were legally on the Community market when the Regulation became applicable, should comply to the Regulation by December 30, 2012. (b) The hospital exemption rule for non-routine products for an individual patient. In this work we explored whether the actual application of the Regulation on ATMPs is in line with the aim of the Regulation in terms of guaranteeing the highest level of health protection for patients. Based on the analysis of the relative efficacy of the only EC authorized ATMP and its exempted alternatives, there is evidence against this Regulation 1394/2007 assumption.

  18. Optomotor-blind negatively regulates Drosophila eye development by blocking Jak/STAT signaling.

    Directory of Open Access Journals (Sweden)

    Yu-Chen Tsai

    Full Text Available Organ formation requires a delicate balance of positive and negative regulators. In Drosophila eye development, wingless (wg is expressed at the lateral margins of the eye disc and serves to block retinal development. The T-box gene optomotor-blind (omb is expressed in a similar pattern and is regulated by Wg. Omb mediates part of Wg activity in blocking eye development. Omb exerts its function primarily by blocking cell proliferation. These effects occur predominantly in the ventral margin. Our results suggest that the primary effect of Omb is the blocking of Jak/STAT signaling by repressing transcription of upd which encodes the Jak receptor ligand Unpaired.

  19. 77 FR 25865 - Amendment to the International Traffic in Arms Regulations: Exemption for Temporary Export of...

    Science.gov (United States)

    2012-05-02

    ... temporary export of chemical agent protective gear for personal use. The exemption for body armor is amended to also cover helmets when they are included with the body armor. An exemption for firearms and ammunition is clarified by removing certain extraneous language that does not change the meaning of...

  20. 78 FR 59226 - Clarification of Implementation of Regulations and Exemption Policy With Regard to Early...

    Science.gov (United States)

    2013-09-26

    ... for America (A4A) and the Regional Airline Association (RAA), asking for an industry-wide exemption to... from American Airlines and A4A have met with FAA officials and requested that FAA consider allowing... concerns raised in the implementation questions, the A4A/RAA exemption petition, and the American...

  1. 12 CFR 203.3 - Exempt institutions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Exempt institutions. 203.3 Section 203.3 Banks... DISCLOSURE (REGULATION C) § 203.3 Exempt institutions. (a) Exemption based on state law. (1) A state-chartered or state-licensed financial institution is exempt from the requirements of this regulation if...

  2. 75 FR 60862 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-10-01

    ...-0174] Qualification of Drivers; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety... decision to renew the exemptions from the vision requirement in the Federal Motor Carrier Safety Regulations for 18 individuals. FMCSA has statutory authority to exempt individuals from the...

  3. Cytosolic nucleotides block and regulate the Arabidopsis vacuolar anion channel AtALMT9.

    Science.gov (United States)

    Zhang, Jingbo; Martinoia, Enrico; De Angeli, Alexis

    2014-09-12

    The aluminum-activated malate transporters (ALMTs) form a membrane protein family exhibiting different physiological roles in plants, varying from conferring tolerance to environmental Al(3+) to the regulation of stomatal movement. The regulation of the anion channels of the ALMT family is largely unknown. Identifying intracellular modulators of the activity of anion channels is fundamental to understanding their physiological functions. In this study we investigated the role of cytosolic nucleotides in regulating the activity of the vacuolar anion channel AtALMT9. We found that cytosolic nucleotides modulate the transport activity of AtALMT9. This modulation was based on a direct block of the pore of the channel at negative membrane potentials (open channel block) by the nucleotide and not by a phosphorylation mechanism. The block by nucleotides of AtALMT9-mediated currents was voltage dependent. The blocking efficiency of intracellular nucleotides increased with the number of phosphate groups and ATP was the most effective cellular blocker. Interestingly, the ATP block induced a marked modification of the current-voltage characteristic of AtALMT9. In addition, increased concentrations of vacuolar anions were able to shift the ATP block threshold to a more negative membrane potential. The block of AtALMT9-mediated anion currents by ATP at negative membrane potentials acts as a gate of the channel and vacuolar anion tune this gating mechanism. Our results suggest that anion transport across the vacuolar membrane in plant cells is controlled by cytosolic nucleotides and the energetic status of the cell.

  4. 78 FR 43785 - Exemptive Order Regarding Compliance With Certain Swap Regulations

    Science.gov (United States)

    2013-07-22

    ... English, or if not, accompanied by an English translation. Comments will be posted as received to www.cftc... uncleared swaps; (3) trade execution; \\33\\ (4) swap trading relationship documentation; \\34\\ (5) portfolio... exempting any transaction or class of transaction from any of the provisions of the CEA (subject to...

  5. 40 CFR 152.20 - Exemptions for pesticides adequately regulated by another Federal agency.

    Science.gov (United States)

    2010-07-01

    ... microscopic element, including, but not limited to, viruses. (4) All living plants intended for use as biological control agents are exempt from the requirements of FIFRA. However, plant-incorporated protectants... Federal agency. (a) Certain biological control agents. (1) Except as provided by paragraphs (a)(3) and...

  6. 76 FR 37766 - Specified Commodities Imported Into the United States, Exempt From Import Regulations; Request...

    Science.gov (United States)

    2011-06-28

    ... Agricultural Marketing Service Specified Commodities Imported Into the United States, Exempt From Import... Act of 1995 (44 U.S.C. 3501), this document announces the Agricultural Marketing Service's (``AMS... information collection. Abstract: Section 8e of the Agricultural Marketing Agreement Act of 1937 as amended...

  7. 78 FR 61153 - Post-Employment Conflict of Interest Regulations; Exempted Senior Employee Positions

    Science.gov (United States)

    2013-10-03

    ... (APA). Further, under 5 U.S.C. 553(b)(3)(A), notice and comment rulemaking requirements do not apply to... comment requirements of the APA do not apply here. Even if this rulemaking were subject to APA proposed... comment requirements of the APA. The codification of OGE's revocation of exempted positions is...

  8. 40 CFR 90.906 - Manufacturer-owned exemption and precertification exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Manufacturer-owned exemption and... KILOWATTS Exclusion and Exemption of Nonroad Engines from Regulations § 90.906 Manufacturer-owned exemption and precertification exemption. (a) Any manufacturer owned nonroad engine, as defined by § 90.902,...

  9. 45 CFR 1705.12 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Exemptions. 1705.12 Section 1705.12 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL COMMISSION ON LIBRARIES AND INFORMATION SCIENCE PRIVACY REGULATIONS § 1705.12 Exemptions. No Commission records system is exempted from the provisions...

  10. 29 CFR 2580.412-27 - Exemption.

    Science.gov (United States)

    2010-07-01

    ... Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT OF LABOR... Exemptions Banking Institutions Subject to Federal Regulation § 2580.412-27 Exemption. An exemption from the... granted whereby banking institutions and trust companies specified in § 2580.412-28 are not required...

  11. 48 CFR 408.706 - Purchase exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Purchase exemptions. 408... People Who Are Blind or Severely Disabled 408.706 Purchase exemptions. Prior to applying to the Committee for a purchase exemption, the chief of the contracting office should provide advance notice to...

  12. 11 CFR 2.4 - Exempted meetings.

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Exempted meetings. 2.4 Section 2.4 Federal Elections FEDERAL ELECTION COMMISSION SUNSHINE REGULATIONS; MEETINGS § 2.4 Exempted meetings. (a) Meetings required by statute to be closed. Meetings concerning matters specifically exempted from disclosure...

  13. Regulation of Aquaporin Z osmotic permeability in ABA tri-block copolymer

    Directory of Open Access Journals (Sweden)

    Wenyuan Xie

    2015-08-01

    Full Text Available Aquaporins are transmembrane water channel proteins present in biological plasma membranes that aid in biological water filtration processes by transporting water molecules through at high speeds, while selectively blocking out other kinds of solutes. Aquaporin Z incorporated biomimetic membranes are envisaged to overcome the problem of high pressure needed, and holds great potential for use in water purification processes, giving high flux while keeping energy consumption low. The functionality of aquaporin Z in terms of osmotic permeability might be regulated by factors such as pH, temperature, crosslinking and hydrophobic thickness of the reconstituted bilayers. Hence, we reconstituted aquaporin Z into vesicles that are made from a series of amphiphilic block copolymers PMOXA-PDMS-PMOXAs with various hydrophobic molecular weights. The osmotic permeability of aquaporin Z in these vesicles was determined through a stopped-flow spectroscopy. In addition, the temperature and pH value of the vesicle solutions were adjusted within wide ranges to investigate the regulation of osmotic permeability of aquaporin Z through external conditions. Our results show that aquaporin Z permeability was enhanced by hydrophobic mismatch. In addition, the water filtration mechanism of aquaporin Z is significantly affected by the concentration of H+ and OH- ions.

  14. 77 FR 33638 - Amendment to the Bank Secrecy Act Regulations-Exemption From the Requirement To Report...

    Science.gov (United States)

    2012-06-07

    ... exemption standard for payroll customers and non-listed businesses to a single bright-line test that will... Administrative Procedure Act (``APA'') allows an agency to dispense with notice and comment when it would be... ``regularly,'' this final rule will make it easier for banks to apply the exemption standard to their...

  15. 77 FR 6784 - Proposed Information Collection; Comment Request; Scientific Research, Exempted Fishing, and...

    Science.gov (United States)

    2012-02-09

    ... generally affect scientific research activities conducted by a scientific research vessel. Persons planning... grant exemptions from fishery regulations for educational or other activities (e.g., using non... reports, 15 hours; exempted educational requests, 4 hours; exempted educational reports, 2...

  16. Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages.

    Science.gov (United States)

    Frankenberger, Casey; Rabe, Daniel; Bainer, Russell; Sankarasharma, Devipriya; Chada, Kiran; Krausz, Thomas; Gilad, Yoav; Becker, Lev; Rosner, Marsha Rich

    2015-10-01

    Triple-negative breast cancer (TNBC) patients have the highest risk of recurrence and metastasis. Because they cannot be treated with targeted therapies, and many do not respond to chemotherapy, they represent a clinically underserved group. TNBC is characterized by reduced expression of metastasis suppressors such as Raf kinase inhibitory protein (RKIP), which inhibits tumor invasiveness. Mechanisms by which metastasis suppressors alter tumor cells are well characterized; however, their ability to regulate the tumor microenvironment and the importance of such regulation to metastasis suppression are incompletely understood. Here, we use species-specific RNA sequencing to show that RKIP expression in tumors markedly reduces the number and metastatic potential of infiltrating tumor-associated macrophages (TAM). TAMs isolated from nonmetastatic RKIP(+) tumors, relative to metastatic RKIP(-) tumors, exhibit a reduced ability to drive tumor cell invasion and decreased secretion of prometastatic factors, including PRGN, and shed TNFR2. RKIP regulates TAM recruitment by blocking HMGA2, resulting in reduced expression of numerous macrophage chemotactic factors, including CCL5. CCL5 overexpression in RKIP(+) tumors restores recruitment of prometastatic TAMs and intravasation, whereas treatment with the CCL5 receptor antagonist Maraviroc reduces TAM infiltration. These results highlight the importance of RKIP as a regulator of TAM recruitment through chemokines such as CCL5. The clinical significance of these interactions is underscored by our demonstration that a signature comprised of RKIP signaling and prometastatic TAM factors strikingly separates TNBC patients based on survival outcome. Collectively, our findings identify TAMs as a previously unsuspected mechanism by which the metastasis-suppressor RKIP regulates tumor invasiveness, and further suggest that TNBC patients with decreased RKIP activity and increased TAM infiltration may respond to macrophage

  17. Direct block of the cystic fibrosis transmembrane conductance regulator Cl(-) channel by niflumic acid.

    Science.gov (United States)

    Scott-Ward, T S; Li, H; Schmidt, A; Cai, Z; Sheppard, D N

    2004-01-01

    Niflumic acid is widely used to inhibit Ca(2+) -activated Cl(-) channels. However, the chemical structure of niflumic acid resembles that of diphenylamine-2-carboxylate, a drug that inhibits the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel. To investigate how niflumic acid inhibits CFTR Cl(-) channel, we studied recombinant wild-type human CFTR in excised inside-out membrane patches. When added to the intracellular solution, niflumic acid caused a concentration- and voltage-dependent decrease of CFTR Cl(-) current with half-maximal inhibitory concentration (K(i)) of 253 microM and Hill co-efficient of approximately 1, at -50 mV. Niflumic acid inhibition of single CFTR Cl(-) channels was characterized by a very fast, flickery block that decreased dramatically current amplitude without altering open-probability. Consistent with these data, spectral analysis of CFTR Cl(-) currents suggested that channel block by niflumic acid was described by the closed open blocked kinetic scheme with blocker on rate (k(on)) = 13.9 x 10(6) M(-1)s(-1), off rate (k(off))=3348 s(-1) and dissociation constant (K(d)) = 241 microM, at -50 mV. Based on these data, we tested the effects of niflumic acid on transepithelial Cl(-) secretion and cyst growth using type I MDCK epithelial cells. Niflumic acid (200 microM) inhibited cAMP-stimulated, bumetanide-sensitive short-circuit current by 55%. Moreover, the drug potently retarded cyst growth. We conclude that niflumic acid is an open-channel blocker of CFTR that inhibits Cl(-) permeation by plugging the channel pore. It or related agents might be of value in the development of new therapies for autosomal dominant polycystic kidney disease.

  18. Growth-Blocking Peptides As Nutrition-Sensitive Signals for Insulin Secretion and Body Size Regulation.

    Directory of Open Access Journals (Sweden)

    Takashi Koyama

    2016-02-01

    Full Text Available In Drosophila, the fat body, functionally equivalent to the mammalian liver and adipocytes, plays a central role in regulating systemic growth in response to nutrition. The fat body senses intracellular amino acids through Target of Rapamycin (TOR signaling, and produces an unidentified humoral factor(s to regulate insulin-like peptide (ILP synthesis and/or secretion in the insulin-producing cells. Here, we find that two peptides, Growth-Blocking Peptide (GBP1 and CG11395 (GBP2, are produced in the fat body in response to amino acids and TOR signaling. Reducing the expression of GBP1 and GBP2 (GBPs specifically in the fat body results in smaller body size due to reduced growth rate. In addition, we found that GBPs stimulate ILP secretion from the insulin-producing cells, either directly or indirectly, thereby increasing insulin and insulin-like growth factor signaling activity throughout the body. Our findings fill an important gap in our understanding of how the fat body transmits nutritional information to the insulin producing cells to control body size.

  19. 29 CFR 2580.412-28 - Conditions of exemption.

    Science.gov (United States)

    2010-07-01

    ... BONDING RULES Exemptions Banking Institutions Subject to Federal Regulation § 2580.412-28 Conditions of exemption. This exemption applies only to those banking institutions and trust companies subject to... Labor Regulations Relating to Labor (Continued) EMPLOYEE BENEFITS SECURITY ADMINISTRATION, DEPARTMENT...

  20. 77 FR 539 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-01-05

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. If granted...) in interstate commerce without meeting the Federal vision requirement. DATES: Comments must...

  1. 78 FR 47818 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-08-06

    ... FR 3316). FOR FURTHER INFORMATION CONTACT: Elaine M. Papp, Chief, Medical Programs Division, (202... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  2. Regulation of methanol metabolism in the yeast Hansenula polymorpha. Isolation and characterization of mutants blocked in methanol assimilatory enzymes

    NARCIS (Netherlands)

    Koning, W. de; Gleeson, M.A.G.; Harder, W.; Dijkhuizen, L.

    1987-01-01

    A study of enzyme profiles in Hansenula polymorpha grown on various carbon substrates revealed that the synthesis of the methanol dissimilatory and assimilatory enzymes is regulated in the same way, namely by catabolite repression and induction by methanol. Mutants of H. polymorpha blocked in dihydr

  3. 15 CFR 30.37 - Miscellaneous exemptions.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Miscellaneous exemptions. 30.37 Section 30.37 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From the Requirements for the...

  4. 29 CFR 570.72 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exemptions. 570.72 Section 570.72 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR... the Employment of Children Below the Age of 16 § 570.72 Exemptions. (a) Student-learners. The...

  5. 48 CFR 2804.506 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Exemptions. 2804.506 Section 2804.506 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General ADMINISTRATIVE MATTERS Electronic Commerce in Contracting 2804.506 Exemptions. Pursuant to FAR 4.506(b),...

  6. Dietary fish oil blocks carcinogen-induced down-regulation of colonic protein kinase C isozymes.

    Science.gov (United States)

    Jiang, Y H; Lupton, J R; Chapkin, R S

    1997-02-01

    In order to elucidate the influence of dietary constituents on colonic intracellular signal transduction, the effect of different fats on rat colonic epithelial protein kinase C (PKC) alpha (classical), delta (novel) and lambda-zeta (atypical) expression was determined in carcinogen-treated animals. Sprague-Dawley rats were provided with one of two fats (corn oil and fish oil); plus or minus the carcinogen azoxymethane (AOM) and killed at two time points (15 and 37 weeks) in a 2x2x2 factorial design. At 5 and 6 weeks of age, animals were injected s.c. with either AOM at a dose of 15 mg/kg body weight or saline once a week for 2 weeks and continued on the same diet until termination of the study. At 15 and 37 weeks after the second injection, 10 rats from each treatment group were killed. Colonic PKC alpha, delta and lambda-zeta steady-state protein and mRNA levels were determined using immunoblotting and relative quantitative polymerase chain reaction, respectively. Colonic mucosa from rats injected with AOM had significantly suppressed membrane and cytosolic PKC alpha and cytosolic lambda-zeta protein levels (P fish oil diets had significantly higher (P protein levels relative to animals fed corn oil diets. However, the effect of diet and AOM on the steady-state expression of PKC alpha, delta and zeta mRNA was not consistent with changes in the respective isozyme protein levels, suggesting regulation at the post-transcriptional level. These data demonstrate that dietary fish oil blocks the carcinogen-induced decrease in the steady-state levels of colonic mucosal PKC delta and lambda-zeta, which may in part explain why this fat source protects against colon cancer development.

  7. 7 CFR 932.55 - Exemption.

    Science.gov (United States)

    2010-01-01

    ... Regulating Handling Regulations § 932.55 Exemption. (a) The provisions of this subpart shall not be... such types of shipments, or for such specified purposes (including shipments to facilitate the...

  8. 48 CFR 252.229-7002 - Customs exemptions (Germany).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Customs exemptions... of Provisions And Clauses 252.229-7002 Customs exemptions (Germany). As prescribed in 229.402-70(b), use the following clause: Customs Exemptions (Germany) (JUN 1997) Imported products required for...

  9. 48 CFR 252.229-7003 - Tax Exemptions (Italy).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Tax Exemptions (Italy... of Provisions And Clauses 252.229-7003 Tax Exemptions (Italy). As prescribed in 229.402-70(c), use the following clause: Tax Exemptions (Italy) (JAN 2002) (a) The Contractor represents that...

  10. 12 CFR 711.5 - Small market share exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Small market share exemption. 711.5 Section 711.5 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS MANAGEMENT OFFICIAL INTERLOCKS § 711.5 Small market share exemption. (a) Exemption. A management...

  11. 75 FR 38603 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-02

    ...; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice... the vision requirement in the Federal Motor Carrier Safety Regulations for 21 individuals. FMCSA has statutory authority to exempt individuals from the vision requirement if the exemptions granted will...

  12. 75 FR 19676 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-15

    ... of Drivers; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA... the exemptions from the vision requirement in the Federal Motor Carrier Safety Regulations for 15 individuals. FMCSA has statutory authority to exempt individuals from the vision requirement if the...

  13. 7 CFR 985.58 - Exempt oil.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exempt oil. 985.58 Section 985.58 Agriculture... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Volume Limitations § 985.58 Exempt oil. Oil held by a producer or handler on the effective date of this subpart shall not...

  14. 16 CFR 444.5 - State exemptions.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false State exemptions. 444.5 Section 444.5 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES CREDIT PRACTICES § 444.5 State exemptions. (a) If, upon application to the Federal Trade Commission by an appropriate State agency,...

  15. 41 CFR 105-50.305 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Exemptions. 105-50.305 Section 105-50.305 Public Contracts and Property Management Federal Property Management Regulations System... UNITS OF GOVERNMENT 50.3-Principles Governing Reimbursements to GSA § 105-50.305 Exemptions. (a)...

  16. Blocking transforming growth factor- receptor signaling down-regulates transforming growth factor-β1 autoproduction in keloid fibroblasts

    Institute of Scientific and Technical Information of China (English)

    刘伟; 蔡泽浩; 王丹茹; 武小莉; 崔磊; 商庆新; 钱云良; 曹谊林

    2002-01-01

    Objective: To study transforming growth factor-β1(TGF-β1) autoproduction in keloid fibroblasts and theregulation effect of blocking TGF-β intracellular signalingon rhTGF-β1 autoproduction.Methods: Keloid fibroblasts cultured in vitro weretreated with either rhTGF-β1 (5 ng/ml ) or recombinantadenovirus containing a truncated type II TGF-β receptorgene (50 pfu/cell ). Their effects of regulating geneexpression of TGF-β1 and its receptor I and II wereobserved with Northern blot.Results: rhTGF-β1 up-regulated the gene expressionof TGF-β1 and receptor I, but not receptor II. Over-expression of the truncated receptor II down-regulated thegene expression of TGF-β1 and its receptor I, but notreceptor II.Conclusions: TGF-β1 autoproduction was observed inkeloid fibroblasts. Over-expression of the truncated TGF-βreceptor H decreased TGF-β1 autoproduction via blockingTGF-β receptor signaling.

  17. 48 CFR 29.305 - State and local tax exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false State and local tax exemptions. 29.305 Section 29.305 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES State and Local Taxes 29.305 State and local tax exemptions....

  18. 48 CFR 29.203 - Other Federal tax exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Other Federal tax exemptions. 29.203 Section 29.203 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES Federal Excise Taxes 29.203 Other Federal tax exemptions....

  19. Basis for applying for exemption according to species protection regulation. Final repository for spent nuclear fuel at Forsmark; Underlag till ansoekan om dispens enligt artskyddsfoerordningen. Slutfoervar foer anvaent kaernbraensle i Forsmark

    Energy Technology Data Exchange (ETDEWEB)

    2011-02-15

    SKB will submit applications for permits and admissibility under the Environmental Act and under the Nuclear Activities Act to construct and operate a disposal facility for spent nuclear fuel at Forsmark. In the final repository the spent nuclear fuel from Swedish nuclear power plants is placed in order to protect human health and the environment against harmful effects of ionizing radiation. Construction and operation of the disposal facility in Forsmark will make an impact, give effects and consequences for the natural environment. Utilization of land for the construction of the facility and the impact on ground water as a result of groundwater drainage is expected to have negative consequences for the species included in species protection regulation. Thus, the planned activity require exemption from species protection regulation (SFS 2007:845). The purpose of this document is to provide a basis for an application for exemption under 14 paragraph species protection regulation from the prohibitions of 4, 6, 7 and 8 paragraph species protection regulation. A basis for the exemption application is that the proposed activity is considered to have an 'overriding public interest' prescribed in 14 paragraph species protection regulation. The document reports the impact, effects and consequences of the planned activities on species covered in the species protection regulation. The impact on protected species can be divided into two categories: - Direct effects on protected species and their habitats by utilization of the land. - Indirect effects on protected species and their habitats in the drainage of groundwater and the effect on groundwater levels. The document also includes a description of planned actions to prevent, restrict and compensate for the effects and consequences that the activity may cause. By applying for an exemption under 14 paragraph species protection regulation in a separate order from the application for permit according to chapters 9

  20. Banning, Blocking and Boosting: Twitter’s Solo-Regulation of Expression

    Directory of Open Access Journals (Sweden)

    Marko Milosavljević

    2016-06-01

    Full Text Available The regulation or self-regulation of online media is one of the key dilemmas of contemporary digital media and policy environment. This includes the new digital intermediary gatekeepers such as social media. The private rules of intermediaries, such as their ‘terms of service’ and content policies, importantly define their functioning and are sometimes thought of as self-regulatory mechanisms. Online intermediaries are increasingly being called upon to engage in codes of conduct or decisions about content. We focus on Twitter as one of the largest and most relevant new gatekeepers because of its use as source of news. The terms and other documents of Twitter are analysed as tools of self-regulation, and as the context within which the individual users and mass media (must function in today’s digital environment. We also look at how Twitter has applied this framework in two high profile cases.

  1. 46 CFR 176.920 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... CERTIFICATION International Convention for Safety of Life at Sea, 1974, as Amended (SOLAS) § 176.920 Exemptions... (Construction—Fire Protection, Fire Detection and Fire Extinction) Regulation 1, and Chapter III (Life...

  2. 49 CFR 376.22 - Exemption for private carrier leasing and leasing between authorized carriers.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Exemption for private carrier leasing and leasing... MOTOR CARRIER SAFETY REGULATIONS LEASE AND INTERCHANGE OF VEHICLES Exemptions for the Leasing Regulations § 376.22 Exemption for private carrier leasing and leasing between authorized carriers....

  3. 7 CFR 947.68 - Review, records, and reports of exemptions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Review, records, and reports of exemptions. 947.68 Section 947.68 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... Order Regulating Handling Exemptions § 947.68 Review, records, and reports of exemptions. (a)...

  4. 75 FR 75722 - Order Extending Temporary Exemptions From Certain Government Securities Act Provisions and...

    Science.gov (United States)

    2010-12-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Order Extending Temporary Exemptions From Certain Government Securities Act Provisions and Regulations... Temporary Exemptions from Certain Provisions of the Government Securities Act and Treasury's...

  5. 48 CFR 2129.305 - State and local tax exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true State and local tax exemptions. 2129.305 Section 2129.305 Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT... TAXES State and Local Taxes 2129.305 State and local tax exemptions. (a) FAR 29.305 is modified for...

  6. 48 CFR 1329.203-70 - DOC Federal tax exemption.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOC Federal tax exemption. 1329.203-70 Section 1329.203-70 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS TAXES Federal Excise Taxes 1329.203-70 DOC Federal tax exemption. (a) The Office...

  7. 48 CFR 1329.203 - Other Federal tax exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Other Federal tax exemptions. 1329.203 Section 1329.203 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS TAXES Federal Excise Taxes 1329.203 Other Federal tax exemptions....

  8. 7 CFR 981.413 - Roadside stand exemption.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Roadside stand exemption. 981.413 Section 981.413 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Administrative Rules and Regulations § 981.413 Roadside stand exemption. The term at retail at a roadside...

  9. Endogenous polyamines regulate cortical neuronal excitability by blocking voltage-gated Na+ channels.

    Science.gov (United States)

    Fleidervish, Ilya A; Libman, Lior; Katz, Efrat; Gutnick, Michael J

    2008-12-02

    Because the excitable properties of neurons in the neocortex depend on the characteristics of voltage-gated Na(+) channels, factors which regulate those characteristics can fundamentally modify the dynamics of cortical circuits. Here, we report on a novel neuromodulatory mechanism that links the availability of Na(+) channels to metabolism of polyamines (PAs) in the cerebral cortex. Using single channel and whole-cell recordings, we found that products of PA metabolism, the ubiquitous aliphatic polycations spermine and spermidine, are endogenous blockers of Na(+) channels in layer 5 pyramidal cells. Because the blockade is activity-dependent, it is particularly effective against Na(+) channels which fail to inactivate rapidly and thus underlie the persistent Na(+) current. At the level of the local cortical circuit, pharmacological depletion of PAs led to increased spontaneous spiking and periods of hypersynchronous discharge. Our data suggest that changes in PA levels, whether associated with normal brain states or pathological conditions, profoundly modify Na(+) channel availability and thereby shape the integrative behavior of single neurons and neocortical circuits.

  10. Doxycycline blocks gastric ulcer by regulating matrix metalloproteinase-2 activity and oxidative stress

    Institute of Scientific and Technical Information of China (English)

    Laishram Pradeepkumar Singh; Amartya Mishra; Debjit Saha; Snehasikta Swarnakar

    2011-01-01

    AIM: To examine the effect of doxycycline on the activity of matrix metalloproteinases (MMPs) and oxidative stress in gastric tissues of rats following gastric injury. METHODS: Gastric ulcers were generated in rats by administration of 70% ethanol, and activity of doxycycline was tested by administration 30 min prior to ethanol. Similarly, the effect of doxycycline was tested in an indomethacin-induced gastric ulcer model. The activities and expression of MMPs were examined by zymography and Western blot analysis. RESULTS: Gastric injury in rats as judged by elevated ulcer indices following exposure to ulcerogen, either indomethacin or ethanol, was reversed significantly by doxycycline. Indomethacin-induced ulcerated gastric tissues exhibited about 12-fold higher proMMP-9 activity and about 5-fold higher proMMP-3 activity as compared to control tissues. Similarly, ethanol induced about 22-fold and about 6-fold higher proMMP-9 and proMMP-3 activities, respectively, in rat gastric tissues. Both proMMP-9 and MMP-3 activities were markedly decreased by doxycycline in ulcerogen treated rat gastric tissues. In contrast, the reduced MMP-2 activity in ulcerated tissues was increased by doxycycline during ulcer prevention. On the other hand, doxycycline inhibited significantly proMMP-9, -2 and -3 activities in vitro . In addition, doxycycline reduced oxidative load in gastric tissues and scavenged H2O2 in vitro . Our results suggest a novel regulatory role of doxycycline on MMP-2 activity in addition to inhibitory action on MMP-9 and MMP-3 during prevention of gastric ulcers. CONCLUSION: This is the first demonstration of dual action of doxycycline, that is, regulation of MMP activity and reduction of oxidative stress in arresting gastric injury.

  11. Regulation of coenzyme Q biosynthesis in yeast: a new complex in the block.

    Science.gov (United States)

    González-Mariscal, Isabel; García-Testón, Elena; Padilla, Sergio; Martín-Montalvo, Alejandro; Pomares-Viciana, Teresa; Vazquez-Fonseca, Luis; Gandolfo-Domínguez, Pablo; Santos-Ocaña, Carlos

    2014-02-01

    Coenzyme Q (CoQ) is an isoprenylated benzoquinone found in mitochondria, which functions mainly as an electron carrier from complex I or II to complex III in the inner membrane. CoQ is also an antioxidant that specifically prevents the oxidation of lipoproteins and the plasma membrane. Most of the information about the synthesis of CoQ comes from studies performed in Saccharomyces cerevisiae. CoQ biosynthesis is a highly regulated process of sequential modifications of the benzene ring. There are three pieces of evidence supporting the involvement of a multienzymatic complex in yeast CoQ6 biosynthesis: (a) the accumulation of a unique early precursor in all null mutants of the COQ genes series, 4-hydroxy-3-hexaprenyl benzoate (HHB), (b) the lack of expression of several Coq proteins in COQ null mutants, and (c) the restoration of CoQ biosynthesis complex after COQ8 overexpression. The model we propose based on the formation of a multiprotein complex should facilitate a better understanding of CoQ biosynthesis. According to this model, the complex assembly requires the synthesis of a precursor such as HHB by Coq2p that must be recognized by the regulatory protein Coq4p to act as the core component of the complex. The phosphorylation of Coq3p and Coq5p by the kinase Coq8p facilitates the formation of an initial precomplex of 700 kDa that contains all Coq proteins with the exception of Coq7p. The precomplex is required for the synthesis of 5-demethoxy-Q6 , the substrate of Coq7p. When cells require de novo CoQ6 synthesis, Coq7p is dephosphorylated by Ptc7p, a mitochondrial phosphatase that activates the synthesis of CoQ6. This event allows for the full assembly of a complex of 1,300 kDa that is responsible for the final product of the pathway, CoQ6 .

  12. 29 CFR 570.126 - Parental exemption.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Parental exemption. 570.126 Section 570.126 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS, ORDERS AND STATEMENTS OF INTERPRETATION General Statements of Interpretation of the Child...

  13. 29 CFR 780.506 - Dependence of exemption on shade-grown tobacco operations.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Dependence of exemption on shade-grown tobacco operations. 780.506 Section 780.506 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION....506 Dependence of exemption on shade-grown tobacco operations. The exemption provided by section...

  14. 49 CFR 525.11 - Termination of exemption; amendment of alternative average fuel economy standard.

    Science.gov (United States)

    2010-10-01

    ... average fuel economy standard. 525.11 Section 525.11 Transportation Other Regulations Relating to... EXEMPTIONS FROM AVERAGE FUEL ECONOMY STANDARDS § 525.11 Termination of exemption; amendment of alternative average fuel economy standard. (a) Any exemption granted under this part for an affected model year...

  15. 7 CFR 989.72 - Exemption of educational institutions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exemption of educational institutions. 989.72 Section... educational institutions. The committee may exempt, wholly or in part, from the volume regulation provisions of this part, that volume of raisins received or acquired by public or private educational...

  16. 45 CFR 5.68 - Exemption seven: Law enforcement.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Exemption seven: Law enforcement. 5.68 Section 5.68 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION FREEDOM OF INFORMATION REGULATIONS Reasons for Withholding Some Records § 5.68 Exemption seven: Law enforcement. We...

  17. 78 FR 24798 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-04-26

    ... examination in 2012, his ophthalmologist noted, ``Mr. Kimble has poor vision in the left eye caused by a... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  18. 29 CFR 779.356 - Application of exemptions to employees.

    Science.gov (United States)

    2010-07-01

    ...-exempt operations. For example, office workers may keep records of both the retail sales and construction....356 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR... establishment under section 13(a)(4), as explained in § 779.354, the exemption from the minimum wage...

  19. 7 CFR 1219.202 - Exemption for organic Hass avocados.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Exemption for organic Hass avocados. 1219.202 Section... AVOCADO PROMOTION, RESEARCH, AND INFORMATION Rules and Regulations § 1219.202 Exemption for organic Hass avocados. (a) A producer who operates under an approved National Organic Program (NOP) (7 CFR part...

  20. 17 CFR 250.6 - Termination of exemptions.

    Science.gov (United States)

    2010-04-01

    ... order granting such an exemption pursuant to any applicable section of the act, and without prejudice to...) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Registration and General... section now or hereafter in force pursuant to section 3(a) of the Act exempting any class of...

  1. 77 FR 64839 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-10-23

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision... exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable...

  2. Air temperature regulation in mine workings on the basis of local and block ventilation systems with boreholes

    Energy Technology Data Exchange (ETDEWEB)

    Bobrov, A.I.; Batmanov, Y.K.; Lunev, S.G.; Martynov, A.A. [Makeyevka Safety in Mines Research Institute, Makeyevka (Ukraine)

    1997-12-31

    The thermal factor is one of the main factors complicating coal mining in the Donetsk Basin (Ukraine). Local ventilation systems (small diameter boreholes to improve ventilation in individual headings at deep levels) and block ventilation systems (large diameter boreholes for ventilation and air temperature control in independently mined blocks and panels) are discussed. 4 refs., 3 figs.

  3. 44 CFR 6.87 - Specific exemptions.

    Science.gov (United States)

    2010-10-01

    ... deny them a right, privilege, or benefit to which they would otherwise be entitled. (1) Exempt systems... inquiries of suspected violators of civil and criminal laws and regulations under its jurisdiction. In many cases investigations and inquiries into violations of civil and criminal laws and regulations...

  4. A case study of sea breeze blocking regulated by sea surface temperature along the English south coast

    Directory of Open Access Journals (Sweden)

    J. K. Sweeney

    2013-09-01

    Full Text Available The sensitivity of sea breeze structure to sea surface temperature (SST and coastal orography is investigated in convection-permitting Met Office Unified Model simulations of a case study along the south coast of England. Changes in SST of 1 K are shown to significantly modify the structure of the sea breeze. On the day of the case study the sea breeze was partially blocked by coastal orography, particularly within Lyme Bay. The extent to which the flow is blocked depends strongly on the static stability of the marine boundary layer. In experiments with colder SST, the marine boundary layer is more stable, and the degree of blocking is more pronounced. The implications of prescribing fixed SST from climatology in numerical weather prediction model forecasts of the sea breeze are discussed.

  5. Rock blocks

    OpenAIRE

    Turner, W.

    2007-01-01

    Consider representation theory associated to symmetric groups, or to Hecke algebras in type A, or to q-Schur algebras, or to finite general linear groups in non-describing characteristic. Rock blocks are certain combinatorially defined blocks appearing in such a representation theory, first observed by R. Rouquier. Rock blocks are much more symmetric than general blocks, and every block is derived equivalent to a Rock block. Motivated by a theorem of J. Chuang and R. Kessar in the case of sym...

  6. 31 CFR 539.204 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 539.204 Section 539.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY WEAPONS OF MASS DESTRUCTION TRADE CONTROL...

  7. 16 CFR Appendix to Part 460 - Exemptions

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Exemptions Appendix to Part 460 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES LABELING AND ADVERTISING OF HOME INSULATION Pt... type and thickness of the insulation when they make a representation in an advertisement or...

  8. 45 CFR 5b.11 - Exempt systems.

    Science.gov (United States)

    2010-10-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PRIVACY ACT REGULATIONS § 5b.11 Exempt systems... individual to be granted access to an accounting of disclosures of a record. (ii) 5 U.S.C. 552a(d) (1...; and, (D) The Maryland Psychiatric Case Register. (E) The Health Resources Utilization Statistics,...

  9. 12 CFR 711.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false General exemption. 711.6 Section 711.6 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS MANAGEMENT... or substantial lessening of competition if the depository organization seeking to add a...

  10. 43 CFR 2.79 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... regulations in this subpart implementing these paragraphs: (1) Investigative Case File System, Interior/FWS-20... Files System, Interior/Office of the Solicitor-1 to the extent that it consists of investigatory... to 5 U.S.C 552a(j)(2) the following systems of records have been exempted from all of the...

  11. 7 CFR 1160.215 - Assessment exemption.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE FLUID MILK PROMOTION PROGRAM Fluid Milk Promotion Order National Fluid Milk Processor Promotion Board § 1160.215 Assessment exemption. (a) No...

  12. 16 CFR 1501.3 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Exemptions. 1501.3 Section 1501.3 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS METHOD FOR... clothing and accessories, such as shoe lace holders and buttons; (e) Grooming, feeding, and...

  13. Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Dong, E-mail: austhudong@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Wu, Jing, E-mail: wujing8008@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Wang, Wan; Mu, Min; Zhao, Runpeng; Xu, Xuewei; Chen, Zhaoquan [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Xiao, Jian [School of Pharmacy, Wenzhou Medical College, Wenzhou (China); Hu, Fengyu; Yang, Yabo [Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou (China); Zhang, Rongbo, E-mail: lory456@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China)

    2015-05-29

    The mechanism underlying autophagy alteration by mycobacterium tuberculosis remains unclear. Our previous study shows LpqH, a lipoprotein of mycobacterium tuberculosis, can cause autophagosomes accumulation in murine macrophages. It is well known that SapM, another virulence factor, plays an important role in blocking phagosome-endosome fusion. However, the mechanism that SapM interferes with autophagy remains poorly defined. In this study, we report that SapM suppresses the autophagy flux by blocking autophagosome fusion with lysosome. Exposure to SapM results in accumulations of autophagosomes and decreased co-localization of autophagosome with lysosome. Molecularly, Rab7, a small GTPase, is blocked by SapM through its CT domain and is prevented from involvement of autophagosome-lysosome fusion. In conclusion, our study reveals that SapM takes Rab7 as a previously unknown target to govern a distinct molecular mechanism underlying autophagosome-lysosome fusion, which may bring light to a new thought about developing potential drugs or vaccines against tuberculosis. - Highlights: • A mechanism for disrupting autophagosome-lysosome fusion induced by SapM. • Rab7 is involved in SapM-inhibited autophagy. • SapM interacts with Rab7 by CT-domain. • CT-domain is indispensable to SapM-inhibited autophagy.

  14. 15 CFR 30.35 - Procedure for shipments exempt from filing requirements.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Procedure for shipments exempt from filing requirements. 30.35 Section 30.35 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From...

  15. 15 CFR 30.36 - Exemption for shipments destined to Canada.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Exemption for shipments destined to Canada. 30.36 Section 30.36 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE REGULATIONS Exemptions From the...

  16. 48 CFR 53.301-1094A - SF 1094A, Tax Exemption Certificates Accountability Record.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 1094A, Tax Exemption Certificates Accountability Record. 53.301-1094A Section 53.301-1094A Federal Acquisition Regulations System... 1094A, Tax Exemption Certificates Accountability Record. ER02JA97.013 ER02JA97.014...

  17. The politics and strategy of industry self-regulation: the pharmaceutical industry's principles for ethical direct-to-consumer advertising as a deceptive blocking strategy.

    Science.gov (United States)

    Arnold, Denis G; Oakley, James L

    2013-06-01

    As the pharmaceutical industry lobbies European regulators to permit direct-to-consumer advertising (DTCA) of prescription drugs in the European Union, we found that five leading companies violated industry-developed and -promulgated standards for ethical advertising in the United States. Utilizing multiple data sources and methods, we demonstrate a consistent failure by companies that market erectile dysfunction drugs to comply with the industry's guiding principles for ethical DTCA over a four-year period despite pledges of compliance by company leaders. Noncompliance resulted in children being exposed to sexually themed promotional messages more than 100 billion times. We argue that the guidelines are a coordinated effort by the industry to prevent unwanted federal regulation, and we introduce the concept of a blocking strategy to explain company behavior and to advance theoretical understanding of firms' public affairs strategies. We recommend policy responses to prevent deceptive practices, protect children from adult content, and promote genuine health care education.

  18. 48 CFR 970.2902-3 - Other Federal tax exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Other Federal tax exemptions. 970.2902-3 Section 970.2902-3 Federal Acquisition Regulations System DEPARTMENT OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Taxes 970.2902-3 Other Federal tax...

  19. Effector-triggered immunity blocks pathogen degradation of an immunity-associated vesicle traffic regulator in Arabidopsis.

    Science.gov (United States)

    Nomura, Kinya; Mecey, Christy; Lee, Young-Nam; Imboden, Lori Alice; Chang, Jeff H; He, Sheng Yang

    2011-06-28

    Innate immunity in plants can be triggered by microbe- and pathogen-associated molecular patterns. The pathogen-associated molecular pattern-triggered immunity (PTI) is often suppressed by pathogen effectors delivered into the host cell. Plants can overcome pathogen suppression of PTI and reestablish pathogen resistance through effector-triggered immunity (ETI). An unanswered question is how plants might overcome pathogen-suppression of PTI during ETI. Findings described in this paper suggest a possible mechanism. During Pseudomonas syringae pathovar tomato (Pst) DC3000 infection of Arabidopsis, a host ADP ribosylation factor guanine nucleotide exchange factor, AtMIN7, is destabilized by the pathogen effector HopM1 through the host 26S proteasome. In this study, we discovered that AtMIN7 is required for not only PTI, consistent with the notion that Pst DC3000 degrades AtMIN7 to suppress PTI, but also ETI. The AtMIN7 level in healthy plants is low, but increases posttranscriptionally in response to activation of PTI. Whereas DC3000 infection led to degradation of AtMIN7, activation of ETI by three different effectors, AvrRpt2, AvrPphB, and HopA1, in Col-0 plants blocks the ability of Pst DC3000 to destabilize AtMIN7. Further analyses of bacterial translocation of HopM1 and AtMIN7 stability in HopM1 transgenic plants show that ETI prevents HopM1-mediated degradation of AtMIN7 inside the plant cell. Both AtMIN7 and HopM1 are localized to the trans-Golgi network/early endosome, a subcellular compartment that is not previously known to be associated with bacterial pathogenesis in plants. Thus, blocking pathogen degradation of trans-Golgi network/early endosome-associated AtMIN7 is a critical part of the ETI mechanism to counter bacterial suppression of PTI.

  20. Guide to Application, Transsction and Administration for Duty Reduction or Exemption

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Goods under duty reduction or exemption is a tariff preference measure that the state gives to the qualified enterprises and units.When enjoying the right of duty reduction or exemption,enterprises and units shall value this right and assume the responsibility to apply for,to use,to take care of and to deal with the goods under duty reduction or exemption in accordance with laws and regulations.

  1. 78 FR 34894 - Regulated Navigation Area, Gulf of Mexico: Mississippi Canyon Block 20, South of New Orleans, LA...

    Science.gov (United States)

    2013-06-11

    ... submit your comment online, go to http://www.regulations.gov , type the docket number in the ``SEARCH... , type the docket number in the ``SEARCH'' box and click ``SEARCH.'' Click on Open Docket Folder on the... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF...

  2. The coming changes in tax-exempt health care finance.

    Science.gov (United States)

    Carlile, L L; Serchuk, B M

    1995-01-01

    On December 30, 1994, the Internal Revenue Service (IRS) published proposed regulations (Proposed Regulations) that if enacted would significantly change the climate and rules of federal income tax law controlling the issuance and maintenance of tax-exempt bonds for governmental and 501(c)(3) health care borrowers. This article (1) summarizes the aspects of the Proposed Regulations dealing with private activity tests, management contracts, allocation and accounting rules, change in use of financed facilities, and antiabuse rules, and (2) summarizes the possible interrelationship of the IRS's audit program for tax-exempt bonds and the Proposed Regulations. The article reviews features of the Proposed Regulations that will affect either the costs or administrative burdens of managing the federal tax compliance of future tax-exempt health care borrowings.

  3. Population Blocks.

    Science.gov (United States)

    Smith, Martin H.

    1992-01-01

    Describes an educational game called "Population Blocks" that is designed to illustrate the concept of exponential growth of the human population and some potential effects of overpopulation. The game material consists of wooden blocks; 18 blocks are painted green (representing land), 7 are painted blue (representing water); and the remaining…

  4. The Subject of Exemption

    DEFF Research Database (Denmark)

    Hamre, Bjørn; Fristrup, Tine; Christensen, Gerd

    2016-01-01

    This article examines the constructions of the deviant subject in Danish Foucauldian educational research. Following the work of Foucault, we argue that the deviant subject, on the one hand, could be considered as a subject of exemption. In this case, exemption is deduced from Foucault’s understa......This article examines the constructions of the deviant subject in Danish Foucauldian educational research. Following the work of Foucault, we argue that the deviant subject, on the one hand, could be considered as a subject of exemption. In this case, exemption is deduced from Foucault...... discourses of general education. Thus, this article argues that Foucauldian disability studies could benefit from taking into account Foucauldian research in the field of general education. Until recently, the two research fields have been mutually isolated....

  5. Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression.

    Directory of Open Access Journals (Sweden)

    Alessio Ligabue

    Full Text Available BACKGROUND: 5-fluorouracil, a commonly used chemotherapeutic agent, up-regulates expression of human thymidylate synthase (hTS. Several different regulatory mechanisms have been proposed to mediate this up-regulation in distinct cell lines, but their specific contributions in a single cell line have not been investigated to date. We have established the relative contributions of these previously proposed regulatory mechanisms in the ovarian cancer cell line 2008 and the corresponding cisplatin-resistant and 5-FU cross-resistant-subline C13*. METHODOLOGY/PRINCIPAL FINDINGS: Using RNA polymerase II inhibitor DRB treated cell cultures, we showed that 70-80% of up-regulation of hTS results from transcriptional activation of TYMS mRNA. Moreover, we report that 5-FU compromises the cell cycle by blocking the 2008 and C13* cell lines in the S phase. As previous work has established that TYMS mRNA is synthesized in the S and G(1 phase and hTS is localized in the nuclei during S and G(2-M phase, the observed cell cycle changes are also expected to affect the intracellular regulation of hTS. Our data also suggest that the inhibition of the catalytic activity of hTS and the up-regulation of the hTS protein level are not causally linked, as the inactivated ternary complex, formed by hTS, deoxyuridine monophosphate and methylenetetrahydrofolate, was detected already 3 hours after 5-FU exposure, whereas substantial increase in global TS levels was detected only after 24 hours. CONCLUSIONS/SIGNIFICANCE: Altogether, our data indicate that constitutive TYMS mRNA transcription, cell cycle-induced hTS regulation and hTS enzyme stability are the three key mechanisms responsible for 5-fluorouracil induced up-regulation of human thymidylate synthase expression in the two ovarian cancer cell lines studied. As these three independent regulatory phenomena occur in a precise order, our work provides a feasible rationale for earlier observed synergistic combinations of 5

  6. Zitongdong Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ The Zitongdong Block (Eastern Zitong Block) is located in the northwest of the Sichuan Basin. Tectonically, it is situated in the east part of Zitong Depression, southeast of mid-Longmenshan folded and faulted belt( as shown on Fig. 8 ), covering an area of 1 730 km2. The traffic is very convenient, the No. 108 national highway passes through the north of the block. Topographically, the area belongs to low hilly land at the elevation of 500-700 m.

  7. 7 CFR 3565.6 - Inclusion of tax-exempt debt.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Inclusion of tax-exempt debt. 3565.6 Section 3565.6 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM General Provisions § 3565.6 Inclusion of tax-exempt...

  8. 77 FR 19109 - Bacillus Pumilus Strain GHA 180; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2012-03-30

    ... AGENCY 40 CFR Part 180 Bacillus Pumilus Strain GHA 180; Exemption From the Requirement of a Tolerance... an exemption from the requirement of a tolerance for residues of Bacillus pumilus strain GHA 180 in... permissible level for residues of Bacillus pumilus strain GHA 180. DATES: This regulation is effective...

  9. 78 FR 35147 - Bacillus pumilus Strain BU F-33; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2013-06-12

    ... AGENCY 40 CFR Part 180 Bacillus pumilus Strain BU F-33; Exemption From the Requirement of a Tolerance... an exemption from the requirement of a tolerance for residues of Bacillus pumilus strain BU F-33 in... residues of Bacillus pumilus strain BU F-33 under the FFDCA. DATES: This regulation is effective June...

  10. 15 CFR Appendix D to Part 30 - AES Filing Citation, Exemption and Exclusion Legends

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false AES Filing Citation, Exemption and Exclusion Legends D Appendix D to Part 30 Commerce and Foreign Trade Regulations Relating to Commerce and... Appendix D to Part 30—AES Filing Citation, Exemption and Exclusion Legends I. USML Proof of Filing...

  11. 50 CFR 18.25 - Exempted marine mammals or marine mammal products.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Exempted marine mammals or marine mammal... IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) MARINE MAMMALS General Exceptions § 18.25 Exempted marine mammals or marine mammal products. (a) The provisions of the Act and these regulations shall not apply:...

  12. 50 CFR 216.25 - Exempted marine mammals and marine mammal products.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Exempted marine mammals and marine mammal... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS General Exceptions § 216.25 Exempted marine mammals and marine...

  13. 78 FR 69753 - Exemption of Records Systems Under the Privacy Act

    Science.gov (United States)

    2013-11-21

    ... Part 16 Exemption of Records Systems Under the Privacy Act AGENCY: Executive Office for Organized Crime... Department of Justice (the Department or DOJ) amends its Privacy Act regulations for two Privacy Act systems... Criminal Division, these systems were exempted from certain provisions of the Privacy Act of 1974...

  14. 76 FR 53678 - Calleguas Municipal Water District Notice of Surrender of Exemption (Conduit)

    Science.gov (United States)

    2011-08-29

    ... Federal Energy Regulatory Commission Calleguas Municipal Water District Notice of Surrender of Exemption (Conduit) Pursuant to section 4.95(a) of the Commission's regulations,\\1\\ Calleguas Municipal Water... exemption for Project No. 11651 on June 7, 1999. Calleguas Municipal Water District, 87 FERC ] 62,256...

  15. 29 CFR 780.704 - Dependence of exemption on nature of employing establishment.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Dependence of exemption on nature of employing establishment. 780.704 Section 780.704 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... Elevator § 780.704 Dependence of exemption on nature of employing establishment. If an employee is to...

  16. 29 CFR 794.103 - Dependence of exemption on engagement in described distribution.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Dependence of exemption on engagement in described distribution. 794.103 Section 794.103 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... Act Scope and Application in General § 794.103 Dependence of exemption on engagement in...

  17. 29 CFR 794.119 - Dependence of exemption on sales volume of the enterprise.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Dependence of exemption on sales volume of the enterprise. 794.119 Section 794.119 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... Act Annual Gross Volume of Sales § 794.119 Dependence of exemption on sales volume of the...

  18. 77 FR 27097 - LaCrosse Boiling Water Reactor, Exemption From Certain Requirements, Vernon County, WI

    Science.gov (United States)

    2012-05-08

    ... COMMISSION LaCrosse Boiling Water Reactor, Exemption From Certain Requirements, Vernon County, WI AGENCY...) requesting exemptions from certain security requirements in Title 10 of the Code Federal Regulations (10 CFR) 73.55, for the LaCrosse Boiling Water Reactor (LACBWR). This Environmental Assessment (EA) has...

  19. 40 CFR 80.606 - What national security exemption applies to fuels covered under this subpart?

    Science.gov (United States)

    2010-07-01

    .... (b) The exempt fuel must meet any of the following: (1) The motor vehicle diesel fuel standards of... PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel; Nonroad, Locomotive, and Marine Diesel Fuel; and ECA Marine Fuel Exemptions § 80.606...

  20. 29 CFR 780.405 - Exemption is direct and does not mean activities are agriculture.

    Science.gov (United States)

    2010-07-01

    ... agriculture. 780.405 Section 780.405 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture or Irrigation That Is Exempted From the Overtime...

  1. 17 CFR 250.49 - Certain exemptions granted to non-utility subsidiaries.

    Science.gov (United States)

    2010-04-01

    ... than an associate or an affiliate of the acquiring company or an affiliate of an associate company, of... EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935...-utility subsidiaries. (a) Companies exempted. The exemptions provided by this section shall apply to...

  2. 17 CFR 270.18c-1 - Exemption of privately held indebtedness.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption of privately held... (CONTINUED) RULES AND REGULATIONS, INVESTMENT COMPANY ACT OF 1940 § 270.18c-1 Exemption of privately held... outstanding any publicly held indebtedness, and all securities of any such class are (a) privately held by...

  3. Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells

    Science.gov (United States)

    Shahi, Mehdi Hayat; Holt, Roseline; Rebhun, Robert B.

    2014-01-01

    The Hedgehog-GLI signaling pathway is active in a variety of human malignancies and is known to contribute to the growth and survival of human osteosarcoma cells. In this study, we examined the expression and regulation of GLI transcription factors in multiple canine osteosarcoma cell lines and analyzed the effects of inhibiting GLI with GANT61, a GLI-specific inhibitor. Compared with normal canine osteoblasts, real-time PCR showed that GLI1 and GLI2 were highly expressed in two out of three cell lines and correlated with downstream target gene expression of PTCH1and PAX6. Treatment of canine osteosarcoma cells with GANT61 resulted in decreased expression of GLI1, GLI2, PTCH1, and PAX6. Furthermore, GANT61 inhibited proliferation and colony formation in all three canine osteosarcoma cell lines. The finding that GLI signaling activity is present and active in canine osteosarcoma cells suggests that spontaneously arising osteosarcoma in dogs might serve as a good model for future preclinical testing of GLI inhibitors. PMID:24810746

  4. Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells.

    Directory of Open Access Journals (Sweden)

    Mehdi Hayat Shahi

    Full Text Available The Hedgehog-GLI signaling pathway is active in a variety of human malignancies and is known to contribute to the growth and survival of human osteosarcoma cells. In this study, we examined the expression and regulation of GLI transcription factors in multiple canine osteosarcoma cell lines and analyzed the effects of inhibiting GLI with GANT61, a GLI-specific inhibitor. Compared with normal canine osteoblasts, real-time PCR showed that GLI1 and GLI2 were highly expressed in two out of three cell lines and correlated with downstream target gene expression of PTCH1and PAX6. Treatment of canine osteosarcoma cells with GANT61 resulted in decreased expression of GLI1, GLI2, PTCH1, and PAX6. Furthermore, GANT61 inhibited proliferation and colony formation in all three canine osteosarcoma cell lines. The finding that GLI signaling activity is present and active in canine osteosarcoma cells suggests that spontaneously arising osteosarcoma in dogs might serve as a good model for future preclinical testing of GLI inhibitors.

  5. 77 FR 6471 - Bacillus thuringiensis Cry2Ae Protein in Cotton; Exemption from the Requirement of a Tolerance

    Science.gov (United States)

    2012-02-08

    ... AGENCY 40 CFR Part 174 Bacillus thuringiensis Cry2Ae Protein in Cotton; Exemption from the Requirement of... regulation establishes an exemption from the requirement of a tolerance for residues of Bacillus... residues of Bacillus thuringiensis Cry2Ae protein in cotton under the FFDCA. DATES: This regulation...

  6. Zitongxi Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ Zitongxi Block (Western Zitong Block), is located in Zitong County, northwest of Sichuan Province (as shown on Fig. 8 ). Geologically. it is situated in the Zitong Depression, southwest of the middle Longmenshan faulted and folded belt, covering an area of 1 830 km2. Transportation is very convenient. A crisscross network of highways run through the block and the Baocheng railway is nearby. The climate is moderate. Most area belongs to hilly land with the elevation of 500-600 m.The Tongjiang River runs across the area.

  7. Chengzikou Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ Chengzikou Block is located in the north of Hekou district, Dongying City, Shandong Province, adjacent to Bohai Bay. It can be geographically divided into three units: onshore, transitional zone and offshore ultrashallow zone, totally covering an area of 470 km2. The southern onshore area is low and gentle in topography;the northern shallow sea is at water depths of 2-8 m below sea level, and the transitional zone occupies more than 60% of the whole block. The climate belongs to temperate zone with seasonal wind. Highways are welldeveloped here, and the traffic is very convenient. The Chengzikou Block is about 80 km away from Dongying City and 290 km from Jinan City in the south. The northern offshore area of the block is 160 km away from Longkou port in the east and only 38 km away in the west from Zhuangxi port.

  8. Longmenshan Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ Longmenshan Block is located in Jiange County of Jiangyou City in the northwest of Sichuan Basin. covering an area of 2 628 km2. Geologically, it is situated in the Mid-Longmenshan fault and fold belt, neighbouring Zitong Depression in its southeast. There are mountains surrounding its northwest , the rest area being hilly land,with the elevation of 500-700 m. The BaoCheng railway and the No. 108 highway run through the block, the traffic is very convenient.

  9. Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway.

    Science.gov (United States)

    Bhui, Kulpreet; Prasad, Sahdeo; George, Jasmine; Shukla, Yogeshwer

    2009-09-18

    Chemoprevention impels the pursuit for either single targeted or cocktail of multi-targeted agents. Bromelain, potential agent in this regard, is a pharmacologically active compound, present in stems and fruits of pineapple (Ananas cosmosus), endowed with anti-inflammatory, anti-invasive and anti-metastatic properties. Herein, we report the anti tumor-initiating effects of bromelain in 2-stage mouse skin tumorigenesis model. Pre-treatment of bromelain resulted in reduction in cumulative number of tumors (CNT) and average number of tumors per mouse. Preventive effect was also comprehended in terms of reduction in tumor volume up to a tune of approximately 65%. Components of the cell signaling pathways, connecting proteins involved in cell death were targeted. Bromelain treatment resulted in upregulation of p53 and Bax and subsequent activation of caspase 3 and caspase 9 with concomitant decrease in Bcl-2. A marked inhibition in cyclooxygenase-2 (Cox-2) expression and inactivation of nuclear factor-kappa B (NF-kappaB) was recorded, as phosphorylation and consequent degradation of I kappa B alpha was blocked by bromelain. Also, bromelain treatment curtailed extracellular signal regulated protein kinase (ERK1/2), p38 mitogen-activated protein kinase (MAPK) and Akt activity. The basis of anti tumor-initiating activity of bromelain was revealed by its time dependent reduction in DNA nick formation and increase in percentage prevention. Thus, modulation of inappropriate cell signaling cascades driven by bromelain is a coherent approach in achieving chemoprevention.

  10. Study on Economic Regulation of Collaborative Strategies among Container Shipping Companies Following Repeal of European Union Regulation 4056/86

    Directory of Open Access Journals (Sweden)

    Rawindaran Nair

    2016-06-01

    Full Text Available The European Union removed the block exemption granted under Regulation 4056/86, to liner shipping companies to provide scheduled services on a collaborative basis effective October 2008. This has also been followed by the proposed P3 alliance with participation of Maersk, MSC and CMA CGM. This paper explores, the arguments adopted by the US Federal Maritime Commission, the European Commission and the Ministry of Commerce of China, in rejecting the case proposed by the P3 alliance. The findings of this paper will inform on understanding strategies adopted by major Competition Regulatory authorities in their interpretation of horizontal collaboration in the industry.

  11. 78 FR 14015 - Medical Devices; Exemption From Premarket Notification; Class II Devices; Powered Patient Transport

    Science.gov (United States)

    2013-03-04

    ... Notification; Class II Devices; Powered Patient Transport AGENCY: Food and Drug Administration, HHS. ACTION... requesting exemption from premarket notification requirements for powered patient transport devices commonly... FDA's powered patient transport regulations, including attendant-operated portable...

  12. 75 FR 75458 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2010-12-03

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment (LOAs), and... and scientific research that is exempt from regulations (e.g., seasons, prohibited species,...

  13. 76 FR 72678 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2011-11-25

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment (LOAs), and... and scientific research that is exempt from regulations (e.g., seasons, prohibited species,...

  14. 76 FR 8942 - Poison Prevention Packaging Requirements; Proposed Exemption of Powder Formulations of...

    Science.gov (United States)

    2011-02-16

    ... COMMISSION 16 CFR Part 1700 Poison Prevention Packaging Requirements; Proposed Exemption of Powder... 1. The Poison Prevention Packaging Act of 1970 and Implementing Regulations The Poison Prevention... children, Packaging and containers, Poison prevention, Toxic substances. For the reasons given above,...

  15. 29 CFR 541.3 - Scope of the section 13(a)(1) exemptions.

    Science.gov (United States)

    2010-07-01

    ..., longshoremen, construction workers and laborers are entitled to minimum wage and overtime premium pay under the Fair Labor Standards Act, and are not exempt under the regulations in this part no matter how...

  16. 78 FR 60291 - Investigational Device Exemptions for Early Feasibility Medical Device Clinical Studies...

    Science.gov (United States)

    2013-10-01

    ... ``Investigational Device Exemptions (IDEs) for Early Feasibility Medical Device Clinical Studies, Including Certain... facilitate early feasibility studies of medical devices, using appropriate risk mitigation strategies, under the IDE regulations. Early feasibility studies allow for limited early clinical evaluations of...

  17. 75 FR 31421 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; Application for Exempted...

    Science.gov (United States)

    2010-06-03

    ... National Oceanic and Atmospheric Administration RIN 0648-XW53 Atlantic Coastal Fisheries Cooperative Management Act Provisions; Application for Exempted Fishing Permit; Horseshoe Crabs AGENCY: National Marine... otherwise restricted by the regulations promulgated under the Atlantic Coastal Fisheries...

  18. Chadong Block

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    @@ The Chadong Block, located in the east of Qaidam Basin, Qinghai Province, covers an area of 12 452 km2. It is bounded by Kunlum Mountains in the south and the northwest is closely adjacent to Aimunike Mountain.Rivers are widely distributed, which always run in NWSE direction, including the Sulunguole, Qaidam and Haluwusu Rivers. The traffic condition is good, the Qinghai-Tibet highway stretching through the whole area and the Lan-Qing railway, 20-50 km away from the block, passing from north to west. A lot of Mongolia minority people have settled there, of which herdsmen always live nearby the Qaidam River drainage area.

  19. EU perspective on VAT exemptions

    OpenAIRE

    Joachim Englisch

    2011-01-01

    As VAT becomes an increasingly important source of tax revenue world-wide, tax policy makers should be well aware of its strengths and weaknesses. In academia, there is strong consensus that tax exemptions rank among the most problematic features of VAT. The very concept of exemption is already a misrepresentation, because it normally entails the loss of entitlement to an input VAT credit; exempt supplies are therefore actually “input-taxed”. It is generally accepted that this particular form...

  20. A Cytostatic Ruthenium(II)-Platinum(II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up-regulating p27(KIP1).

    Science.gov (United States)

    Ramu, Vadde; Gill, Martin R; Jarman, Paul J; Turton, David; Thomas, Jim A; Das, Amitava; Smythe, Carl

    2015-06-15

    Cytostatic agents that interfere with specific cellular components to prevent cancer cell growth offer an attractive alternative, or complement, to traditional cytotoxic chemotherapy. Here, we describe the synthesis and characterization of a new binuclear Ru(II) -Pt(II) complex [Ru(tpy)(tpypma)Pt(Cl)(DMSO)](3+) (tpy=2,2':6',2''-terpyridine and tpypma=4-([2,2':6',2''-terpyridine]-4'-yl)-N-(pyridin-2-ylmethyl)aniline), VR54, which employs the extended terpyridine tpypma ligand to link the two metal centres. In cell-free conditions, VR54 binds DNA by non-intercalative reversible mechanisms (Kb =1.3×10(5)  M(-1) ) and does not irreversibly bind guanosine. Cellular studies reveal that VR54 suppresses proliferation of A2780 ovarian cancer cells with no cross-resistance in the A2780CIS cisplatin-resistant cell line. Through the preparation of mononuclear Ru(II) and Pt(II) structural derivatives it was determined that both metal centres are required for this anti-proliferative activity. In stark contrast to cisplatin, VR54 neither activates the DNA-damage response network nor induces significant levels of cell death. Instead, VR54 is cytostatic and inhibits cell proliferation by up-regulating the cyclin-dependent kinase inhibitor p27(KIP1) and inhibiting retinoblastoma protein phosphorylation, which blocks entry into S phase and results in G1 cell cycle arrest. Thus, VR54 inhibits cancer cell growth by a gain of function at the G1 restriction point. This is the first metal-coordination compound to demonstrate such activity.

  1. 29 CFR 784.137 - Relationship of exemption to exemption for “offshore” activities.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Relationship of exemption to exemption for âoffshoreâ...(a)(4) Exemption § 784.137 Relationship of exemption to exemption for “offshore” activities. The... or by the necessity for consumption or preservation of such products before spoilage occurs...

  2. 22 CFR 123.26 - Recordkeeping requirement for exemptions.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Recordkeeping requirement for exemptions. 123.26 Section 123.26 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS... each such export. The business record should include the following information: A description of...

  3. 78 FR 42585 - Qualification of Drivers; Application for Exemptions; Hearing

    Science.gov (United States)

    2013-07-16

    ... determines the exemptions would satisfy the statutory requirements and decides to grant theses requests after..., 2013. ADDRESSES: You may submit comments bearing the Federal Docket Management System (FDMS) Docket No....regulations.gov , including any personal information provided. Please see the Privacy Act heading below...

  4. 78 FR 12809 - Qualification of Drivers; Application for Exemptions; Hearing

    Science.gov (United States)

    2013-02-25

    ... determines the exemptions would satisfy the statutory requirements and decides to grant theses requests after..., 2013. ADDRESSES: You may submit comments bearing the Federal Docket Management System (FDMS) Docket No....regulations.gov , including any personal information provided. Please see the Privacy Act heading below...

  5. 78 FR 72149 - Qualification of Drivers; Application for Exemptions; Hearing

    Science.gov (United States)

    2013-12-02

    ... determines the exemptions would satisfy the statutory requirements and decides to grant theses requests after..., 2014. ADDRESSES: You may submit comments bearing the Federal Docket Management System (FDMS) Docket No....regulations.gov , including any personal information provided. Please see the Privacy Act heading below...

  6. 9 CFR 381.500 - Exemption from nutrition labeling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Exemption from nutrition labeling. 381.500 Section 381.500 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Nutrition Labeling § 381.500...

  7. 31 CFR 103.55 - Exceptions, exemptions, and reports.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Exceptions, exemptions, and reports. 103.55 Section 103.55 Money and Finance: Treasury Regulations Relating to Money and Finance FINANCIAL RECORDKEEPING AND REPORTING OF CURRENCY AND FOREIGN TRANSACTIONS General Provisions § 103.55...

  8. 29 CFR 780.319 - Basic conditions of exemption.

    Science.gov (United States)

    2010-07-01

    ... OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT... which are common to both sections 13(a)(6)(C) and 13(a)(6)(D) have already been discussed in...

  9. 77 FR 59450 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ... [FMCSA Docket No. FMCSA-2012-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus... insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of...

  10. 7 CFR 1209.52 - Exemption from assessment.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Exemption from assessment. 1209.52 Section 1209.52 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... part 205) system plan; produces only products that are eligible to be labeled as 100 percent...

  11. 7 CFR 1215.52 - Exemption from assessment.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Exemption from assessment. 1215.52 Section 1215.52 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... under an approved National Organic Program (NOP) (7 CFR part 205) system plan; process only...

  12. 77 FR 76979 - Pesticides; Revisions to Minimum Risk Exemption

    Science.gov (United States)

    2012-12-31

    ..., Office of Management and Budget, ATTN: Desk Officer for EPA, 725 17th St. NW., Washington, DC 20503. Hand... exempt under the more ] general terminology used in 40 CFR 152.25(f), which lists only ``cedar oil.'' EPA... from regulation, since the terminology describing the ingredients is difficult to...

  13. 77 FR 41879 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-07-16

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http...; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications... individuals for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations....

  14. 40 CFR 180.1072 - Poly-D-glucosamine (chitosan); exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Poly-D-glucosamine (chitosan... RESIDUES IN FOOD Exemptions From Tolerances § 180.1072 Poly-D-glucosamine (chitosan); exemption from the... of the biological plant growth regulator poly-D-glucosamine when used as a seed treatment in or...

  15. 78 FR 22347 - GPU Nuclear Inc., Three Mile Island Nuclear Power Station, Unit 2, Exemption From Certain...

    Science.gov (United States)

    2013-04-15

    ... licensee has requested exemptions from the cyber security and protection of digital assets regulations as...)(2). Cyber Security under 10 CFR 73.54 is applicable to licensees currently ``licensed to operate a... that reference cyber security or protection of digital assets are not applicable and the exemptions...

  16. 40 CFR 180.1246 - Yeast Extract Hydrolysate from Saccharomyces cerevisiae: exemption from the requirement of a...

    Science.gov (United States)

    2010-07-01

    ... Saccharomyces cerevisiae: exemption from the requirement of a tolerance. 180.1246 Section 180.1246 Protection of... Saccharomyces cerevisiae: exemption from the requirement of a tolerance. This regulation establishes an... Hydrolysate from Saccharomyces cerevisiae on all food commodities when applied/used for the management...

  17. 76 FR 51431 - Prohibited Transaction Exemptions and Grant of Individual Exemptions

    Science.gov (United States)

    2011-08-18

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF LABOR Employee Benefits Security Administration Prohibited Transaction Exemptions and Grant of Individual Exemptions Notice of Technical Correction Prohibited Transaction Exemptions and Grant of...

  18. 78 FR 797 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-01-04

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision...; request for comments. SUMMARY: FMCSA announces its decision to renew the exemptions from the vision... to exempt individuals from the vision requirement if the exemptions granted will not...

  19. 48 CFR 53.301-1094 - SF 1094, U.S. Tax Exemption Certificates.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 1094, U.S. Tax Exemption Certificates. 53.301-1094 Section 53.301-1094 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-1094 SF 1094,...

  20. 40 CFR 166.2 - Types of exemptions.

    Science.gov (United States)

    2010-07-01

    ...: specific, quarantine, public health, and crisis exemptions. (a) Specific exemption. A specific exemption... territories. (c) Public health exemption. A public health exemption may be authorized in an emergency condition to control a pest that will cause a significant risk to human health. (d) Crisis exemption....

  1. Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide

    NARCIS (Netherlands)

    S. Feldt (Sandra); W.W. Batenburg (Wendy); I. Mazak (Istvan); U. Maschke (Ulrike); M. Wellner (Maren); H. Kvakan (Heda); R. Dechend (Ralf); A. Fiebeler (Anette); C. Burckle (Celine); A. Contrepas (Aurelie); A.H.J. Danser (Jan); M. Bader (Michael); G. Nguyen (Genevieve); F.C. Luft (Friedrich); D. Müller (Dominik)

    2008-01-01

    textabstractThe recently cloned (pro)renin receptor [(P)RR] mediates renin-stimulated cellular effects by activating mitogen-activated protein kinases and promotes nonproteolytic prorenin activation. In vivo, (P)RR is said to be blocked with a peptide consisting of 10 amino acids from the prorenin p

  2. 40 CFR 89.906 - Manufacturer-owned exemption and precertification exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Manufacturer-owned exemption and... ENGINES Exemption Provisions § 89.906 Manufacturer-owned exemption and precertification exemption. (a) Except as provided in paragraph (b) of this section, any manufacturer-owned nonroad engine, as defined...

  3. Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction

    Science.gov (United States)

    Sanna, M. Germana; Vincent, Kevin P.; Repetto, Emanuela; Nguyen, Nhan; Brown, Steven J.; Abgaryan, Lusine; Riley, Sean W.; Leaf, Nora B.; Cahalan, Stuart M.; Kiosses, William B.; Kohno, Yasushi; Brown, Joan Heller; McCulloch, Andrew D.

    2016-01-01

    The molecular pharmacology of the G protein–coupled receptors for sphingosine 1-phosphate (S1P) provides important insight into established and new therapeutic targets. A new, potent bitopic S1P3 antagonist, SPM-354, with in vivo activity, has been used, together with S1P3-knockin and S1P3-knockout mice to define the spatial and functional properties of S1P3 in regulating cardiac conduction. We show that S1P3 is a key direct regulator of cardiac rhythm both in vivo and in isolated perfused hearts. 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol in vivo and S1P in isolated hearts induced a spectrum of cardiac effects, ranging from sinus bradycardia to complete heart block, as measured by a surface electrocardiogram in anesthetized mice and in volume-conducted Langendorff preparations. The agonist effects on complete heart block are absent in S1P3-knockout mice and are reversed in wild-type mice with SPM-354, as characterized and described here. Homologous knockin of S1P3-mCherry is fully functional pharmacologically and is strongly expressed by immunohistochemistry confocal microscopy in Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4)-positive atrioventricular node and His-Purkinje fibers, with relative less expression in the HCN4-positive sinoatrial node. In Langendorff studies, at constant pressure, SPM-354 restored sinus rhythm in S1P-induced complete heart block and fully reversed S1P-mediated bradycardia. S1P3 distribution and function in the mouse ventricular cardiac conduction system suggest a direct mechanism for heart block risk that should be further studied in humans. A richer understanding of receptor and ligand usage in the pacemaker cells of the cardiac system is likely to be useful in understanding ventricular conduction in health, disease, and pharmacology. PMID:26494861

  4. Improving European Gas Infrastructure Regulation. Lessons from Theory and Practice

    Energy Technology Data Exchange (ETDEWEB)

    De Joode, J. [Delft University of Technology, Delft (Netherlands); Spanjer, A. [Leiden University, Leiden (Netherlands)

    2010-07-01

    As an instrument to trigger and speed up new investments in gas infrastructure across the European Union, the European Commission has implemented an exemption regime where new investment projects can apply for an exemption from default third party access regulation and tariff regulation. In this contribution we assess access holiday and transaction cost economics' literature and derive conditions for applying an exemption regime. We test whether these conditions are applied in practice by analysing the exemption application process of the Netherlands - UK interconnector (BBL). We conclude that current practice could substantially be improved.

  5. Assessing exemptions under the ballast water management convention: preclude the Trojan horse.

    Science.gov (United States)

    Olenin, Sergej; Ojaveer, Henn; Minchin, Dan; Boelens, Rick

    2016-02-15

    The International Maritime Organization (IMO) Ballast Water Management Convention (BWMC) is a powerful instrument aimed at reducing spread of harmful aquatic organisms and pathogens (HAOPs). As BWMC is expected to enter into force soon, shipping companies will start seeking exemptions for ballast water management in accordance with BWMC Regulation A-4. However, without scientifically robust risk assessment (RA) and consistent rules, the exemptions may introduce a new form of risk within a convention generally designed to reduce risks. This paper describes an adaptive system for granting exemptions, consisting of six major components: target species selection procedure, port-to-port RA, monitoring, information support, administrative decision and review process. The system is based on key principles defined in the IMO guidelines for RA and is designed to continuously accumulate evolving experience on granting exemptions. The ultimate goal is to contribute to the control of the spread of HAOPs, without placing an unnecessary burden on the shipping industry.

  6. 29 CFR 779.419 - Dependence of the section 7(i) overtime pay exemption upon the level of the employee's “regular...

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Dependence of the section 7(i) overtime pay exemption upon the level of the employee's âregular rateâ of pay. 779.419 Section 779.419 Labor Regulations Relating... Compensated Principally by Commissions § 779.419 Dependence of the section 7(i) overtime pay exemption...

  7. 75 FR 32635 - Defense Acquisition Regulations System; Defense Federal Acquisition Regulation Supplement...

    Science.gov (United States)

    2010-06-08

    ... Regulation Supplement; Balance of Payments Program Exemption for Commercial Information Technology... implement in the clauses at 252.225-7044, Balance of Payments Program--Construction Material, and 252.225-7045, Balance of Payments Program--Construction Material under Trade Agreements, the exemption from...

  8. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection.

    Science.gov (United States)

    Marinho, Cintia Ferreira; Azeredo, Elzinandes Leal; Torrentes-Carvalho, Amanda; Marins-Dos-Santos, Alessandro; Kubelka, Claire Fernandes; de Souza, Luiz José; Cunha, Rivaldo Venâncio; de-Oliveira-Pinto, Luzia Maria

    2014-01-01

    In dengue virus (DENV) infection, complement system (CS) activation appears to have protective and pathogenic effects. In severe dengue fever (DF), the levels of DENV non-structural-1 protein and of the products of complement activation, including C3a, C5a and SC5b-9, are higher before vascular leakage occurs, supporting the hypothesis that complement activation contributes to unfavourable outcomes. The clinical manifestations of DF range from asymptomatic to severe and even fatal. Here, we aimed to characterise CS by their receptors or activation product, in vivo in DF patients and in vitro by DENV-2 stimulation on monocytes. In comparison with healthy controls, DF patients showed lower expression of CR3 (CD11b), CR4 (CD11c) and, CD59 on monocytes. The DF patients who were high producers of SC5b-9 were also those that showed more pronounced bleeding or vascular leakage. Those findings encouraged us to investigate the role of CS in vitro, using monocytes isolated from healthy subjects. Prior blocking with CR3 alone (CD11b) or CR3 (CD11b/CD18) reduced viral infection, as quantified by the levels of intracellular viral antigen expression and soluble DENV non-structural viral protein. However, we found that CR3 alone (CD11b) or CR3 (CD11b/CD18) blocking did not influence major histocompatibility complex presentation neither active caspase-1 on monocytes, thus probably ruling out inflammasome-related mechanisms. Although it did impair the secretion of tumour necrosis factor alpha and interferon alpha. Our data provide strategies of blocking CR3 (CD11b) pathways could have implications for the treatment of viral infection by antiviral-related mechanisms.

  9. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection.

    Directory of Open Access Journals (Sweden)

    Cintia Ferreira Marinho

    Full Text Available In dengue virus (DENV infection, complement system (CS activation appears to have protective and pathogenic effects. In severe dengue fever (DF, the levels of DENV non-structural-1 protein and of the products of complement activation, including C3a, C5a and SC5b-9, are higher before vascular leakage occurs, supporting the hypothesis that complement activation contributes to unfavourable outcomes. The clinical manifestations of DF range from asymptomatic to severe and even fatal. Here, we aimed to characterise CS by their receptors or activation product, in vivo in DF patients and in vitro by DENV-2 stimulation on monocytes. In comparison with healthy controls, DF patients showed lower expression of CR3 (CD11b, CR4 (CD11c and, CD59 on monocytes. The DF patients who were high producers of SC5b-9 were also those that showed more pronounced bleeding or vascular leakage. Those findings encouraged us to investigate the role of CS in vitro, using monocytes isolated from healthy subjects. Prior blocking with CR3 alone (CD11b or CR3 (CD11b/CD18 reduced viral infection, as quantified by the levels of intracellular viral antigen expression and soluble DENV non-structural viral protein. However, we found that CR3 alone (CD11b or CR3 (CD11b/CD18 blocking did not influence major histocompatibility complex presentation neither active caspase-1 on monocytes, thus probably ruling out inflammasome-related mechanisms. Although it did impair the secretion of tumour necrosis factor alpha and interferon alpha. Our data provide strategies of blocking CR3 (CD11b pathways could have implications for the treatment of viral infection by antiviral-related mechanisms.

  10. 7 CFR 922.110 - Container exemption.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container exemption. 922.110 Section 922.110... COUNTIES IN WASHINGTON Container Exemption; Waivers of Inspection and Certification § 922.110 Container exemption. Whenever container limitations are effective pursuant to § 922.52, a handler may make...

  11. 48 CFR 719.271-7 - Reports on procurement actions that are exempted from screening.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Reports on procurement actions that are exempted from screening. 719.271-7 Section 719.271-7 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies...

  12. 77 FR 55509 - Indiana Michigan Power Company; Donald C. Cook Nuclear Plant, Unit 2; Exemption

    Science.gov (United States)

    2012-09-10

    ... core cooling systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR 50, ``ECCS... regulations. As written, the regulations presume the use of zircaloy or ZIRLO TM fuel rod cladding. Thus, an... fuel rod cladding material. Accordingly, the licensee requested an exemption that would allow the...

  13. Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors.

    Directory of Open Access Journals (Sweden)

    Xian Zhang

    Full Text Available Epithelial-mesenchymal transition (EMT is the first step required for breast cancer to initiate metastasis. However, the potential of drugs to block and reverse the EMT process are not well explored. In the present study, we investigated the inhibitory effect of beta-elemene (ELE, an active component of a natural plant-derived anti-neoplastic agent in an established EMT model mediated by transforming growth factor-beta1 (TGF-β1. We found that ELE (40 µg/ml blocked the TGF-β1-induced phenotypic transition in the human breast cancer cell line MCF-7. ELE was able to inhibit TGF-β1-mediated upregulation of mRNA and protein expression of nuclear transcription factors (SNAI1, SNAI2, TWIST and SIP1, potentially through decreasing the expression and phosphorylation of Smad3, a central protein mediating the TGF-β1 signalling pathway. These findings suggest a potential therapeutic benefit of ELE in treating basal-like breast cancer.

  14. 40 CFR 166.45 - Duration of crisis exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Duration of crisis exemption. 166.45... EXEMPTION OF FEDERAL AND STATE AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Crisis Exemptions § 166.45 Duration of crisis exemption. A crisis exemption may be authorized for: (a) Only as long as...

  15. 17 CFR 250.3 - Exemption of certain banks.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption of certain banks... Exemptions § 250.3 Exemption of certain banks. (a) General exemption. Subject to the provisions of § 250.6 and to the requirements contained in paragraph (c) of this section, any bank shall be exempt from...

  16. 17 CFR 230.1001 - Exemption for transactions exempt from qualification under § 25102(n) of the California...

    Science.gov (United States)

    2010-04-01

    ... exempt from qualification under § 25102(n) of the California Corporations Code. 230.1001 Section 230... Exempt Under State Law § 230.1001 Exemption for transactions exempt from qualification under § 25102(n... provisions of the Act. In such cases, registration under the Act is required. (a) Exemption. Offers and...

  17. Ultrasound guided supraclavicular block.

    LENUS (Irish Health Repository)

    Hanumanthaiah, Deepak

    2013-09-01

    Ultrasound guided regional anaesthesia is becoming increasingly popular. The supraclavicular block has been transformed by ultrasound guidance into a potentially safe superficial block. We reviewed the techniques of performing supraclavicular block with special focus on ultrasound guidance.

  18. 3D PLUS HI-REL DDR2 Termination Regulator Module- A Building Block Function for High Reliability SDRAM DDR2 System Architecture

    Science.gov (United States)

    Perrot, Nicolas; Dubus, Patrick; Garcia-Sanchez, Esther

    2015-09-01

    Memory system architectures using DDR2 technology need to be compliant with JEDEC JESD8-15A standard [1]. Therefore a bus termination regulator able to sink and source current while regulating VTT voltage is used for this purpose. Such module has been developed by 3D PLUS and is the first space qualified DDR Termination Regulator (DDR2-TR) available on the market. It is based on an innovative Bang-Bang regulation principle, chosen for its speed performance and to guarantee an output voltage that remains within the predefined limits regardless of any output current transients. The output filter type is selected to make the module rugged to any overload condition without complex protection circuits. The module has been specifically designed for low input voltage, low noise and high reliability systems where space is a key consideration. The module uses the 3D PLUS SIP (System-In-Package) technology embedding 3 stacked PCBs. No external filters or decoupling capacitors are needed.

  19. Lauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection.

    Science.gov (United States)

    Dong, Linlin; Li, Xiaolin; Huang, Li; Gao, Ying; Zhong, Lina; Zheng, Yuanyuan; Zuo, Yuanmei

    2014-01-01

    Tomato (Solanum lycopersicum) crops can be severely damaged due to parasitism by the root-knot nematode (RKN) Meloidogyne incognita, but are protected when intercropped with crown daisy (Chrysanthemum coronarium L.). Root exudate may be the determining factor for this protection. An experiment using pots linked by a tube and Petri dish experiments were undertaken to confirm that tomato-crown daisy intercropping root exudate decreased the number of nematodes and alleviated nematode damage, and to determine crown daisy root exudate-regulated nematode chemotaxis. Following a gas chromatography-mass spectrometry assay, it was found that the intercropping protection was derived from the potent bioactivity of a specific root exudate component of crown daisy, namely lauric acid. The Mi-flp-18 gene, encoding an FMRFamide-like peptide neuromodulator, regulated nematode chemotaxis and infection by RNA interference. Moreover, it was shown that lauric acid acts as both a lethal trap and a repellent for M. incognita by specifically regulating Mi-flp-18 expression in a concentration-dependent manner. Low concentrations of lauric acid (0.5-2.0mM) attract M. incognita and consequently cause death, while high concentrations (4.0mM) repel M. incognita. This study elucidates how lauric acid in crown daisy root exudate regulates nematode chemotaxis and disrupts Mi-flp-18 expression to alleviate nematode damage, and presents a general methodology for studying signalling systems affected by plant root exudates in the rhizosphere. This could lead to the development of economical and feasible strategies for controlling plant-parasitic nematodes, and provide an alternative to the use of pesticides in farming systems.

  20. Nerve growth factor blocks the glucose-induced down-regulation of caveolin-1 expression in Schwann cells via p75 neurotrophin receptor signaling.

    Science.gov (United States)

    Tan, Wenbin; Rouen, Shefali; Barkus, Kristin M; Dremina, Yelena S; Hui, Dongwei; Christianson, Julie A; Wright, Douglas E; Yoon, Sung Ok; Dobrowsky, Rick T

    2003-06-20

    Altered neurotrophism in diabetic peripheral neuropathy (DPN) is associated in part with substantial degenerative changes in Schwann cells (SCs) and an increased expression of the p75 neurotrophin receptor (p75NTR). Caveolin-1 (Cav-1) is highly expressed in adult SCs, and changes in its expression can regulate signaling through Erb B2, a co-receptor that mediates the effects of neuregulins in promoting SC growth and differentiation. We examined the hypothesis that hyperglycemia-induced changes in Cav-1 expression and p75NTR signaling may contribute to altered neurotrophism in DPN by modulating SC responses to neuregulins. In an animal model of type 1 diabetes, hyperglycemia induced a progressive decrease of Cav-1 in SCs of sciatic nerve that was reversed by insulin therapy. Treatment of primary neonatal SCs with 20-30 mm d-glucose, but not l-glucose, was sufficient to inhibit transcription from the Cav-1 promoter and decrease Cav-1 mRNA and protein expression. Hyperglycemia prolonged the kinetics of Erb B2 phosphorylation and significantly enhanced the mitogenic response of SCs to neuregulin1-beta1, and this effect was mimicked by the forced down-regulation of Cav-1. Intriguingly, nerve growth factor antagonized the enhanced mitogenic response of SCs to neuregulin1-beta1 and inhibited the glucose-induced down-regulation of Cav-1 transcription, mRNA, and protein expression through p75NTR-dependent activation of JNK. Our data suggest that Cav-1 down-regulation may contribute to altered neurotrophism in DPN by enhancing the response of SCs to neuregulins and that p75NTR-mediated JNK activation may provide a mechanism for the neurotrophic modulation of hyperglycemic stress.

  1. 75 FR 13647 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-03-22

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemptions from the diabetes standard; request for comments. SUMMARY: FMCSA announces receipt of applications from 53 individuals for exemptions from the prohibition against persons with insulin- treated...

  2. 75 FR 14652 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-03-26

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemptions from the diabetes standard; request for comments. SUMMARY: FMCSA announces receipt of applications from 27 individuals for exemptions from the prohibition against persons with insulin- treated...

  3. Block Cipher Analysis

    DEFF Research Database (Denmark)

    Miolane, Charlotte Vikkelsø

    Block ciphersarecryptographicprimitivesthatoperateon fixed sizetexts(blocks). Mostdesigns aim towards secure andfastencryption oflarge amounts ofdata. Block ciphers also serve as the building block of a number of hash functions and message authentication codes(MAC).Thetask of cryptanalysisisto en...... on small scale variants of AES. In the final part of the thesis we present a new block cipher proposal Present and examine its security against algebraic and differential cryptanalysis in particular.......Block ciphersarecryptographicprimitivesthatoperateon fixed sizetexts(blocks). Mostdesigns aim towards secure andfastencryption oflarge amounts ofdata. Block ciphers also serve as the building block of a number of hash functions and message authentication codes(MAC).Thetask of cryptanalysisisto...... ensurethat no attack violatesthe securitybounds specifiedbygeneric attack namely exhaustivekey search and table lookup attacks. This thesis contains a general introduction to cryptography with focus on block ciphers and important block cipher designs, in particular the Advanced Encryption Standard...

  4. Epstein-Barr Virus-Induced Gene 3 (EBI3) Blocking Leads to Induce Antitumor Cytotoxic T Lymphocyte Response and Suppress Tumor Growth in Colorectal Cancer by Bidirectional Reciprocal-Regulation STAT3 Signaling Pathway

    Science.gov (United States)

    Liang, Yanfang; Chen, Qianqian; Du, Wenjing; Chen, Can; Li, Feifei; Yang, Jingying; Peng, Jianyu; Kang, Dongping; Lin, Bihua; Chai, Xingxing; Zhou, Keyuan; Zeng, Jincheng

    2016-01-01

    Epstein-Barr virus-induced gene 3 (EBI3) is a member of the interleukin-12 (IL-12) family structural subunit and can form a heterodimer with IL-27p28 and IL-12p35 subunit to build IL-27 and IL-35, respectively. However, IL-27 stimulates whereas IL-35 inhibits antitumor T cell responses. To date, little is known about the role of EBI3 in tumor microenvironment. In this study, firstly we assessed EBI3, IL-27p28, IL-12p35, gp130, and p-STAT3 expression with clinicopathological parameters of colorectal cancer (CRC) tissues; then we evaluated the antitumor T cell responses and tumor growth with a EBI3 blocking peptide. We found that elevated EBI3 may be associated with IL-12p35, gp130, and p-STAT3 to promote CRC progression. EBI3 blocking peptide promoted antitumor cytotoxic T lymphocyte (CTL) response by inducing Granzyme B, IFN-γ production, and p-STAT3 expression and inhibited CRC cell proliferation and tumor growth to associate with suppressing gp130 and p-STAT3 expression. Taken together, these results suggest that EBI3 may mediate a bidirectional reciprocal-regulation STAT3 signaling pathway to assist the tumor escape immune surveillance in CRC. PMID:27247488

  5. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Science.gov (United States)

    2010-10-01

    ... fishing, and exempted educational activity. 600.745 Section 600.745 Wildlife and Fisheries FISHERY..., exempted fishing, and exempted educational activity. (a) Scientific research activity. Nothing in this part... vessel. Persons planning to conduct scientific research activities on board a scientific research...

  6. STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7.

    Science.gov (United States)

    Dorfman, Julia; Macara, Ian G

    2008-04-01

    LKB1, a serine/threonine kinase, regulates cell polarity, metabolism, and cell growth. The activity and cellular distribution of LKB1 are determined by cofactors, STRADalpha and MO25. STRADalpha induces relocalization of LKB1 from the nucleus to the cytoplasm and stimulates its catalytic activity. MO25 stabilizes the STRADalpha/LKB1 interaction. We investigated the mechanism of nucleocytoplasmic transport of LKB1 in response to its cofactors. Although LKB1 is imported into the nucleus by importin-alpha/beta, STRADalpha and MO25 passively diffuse between the nucleus and the cytoplasm. STRADalpha induces nucleocytoplasmic shuttling of LKB1. STRADalpha facilitates nuclear export of LKB1 by serving as an adaptor between LKB1 and exportins CRM1 and exportin7. STRADalpha inhibits import of LKB1 by competing with importin-alpha for binding to LKB1. MO25 stabilizes the LKB1-STRADalpha complex but it does not facilitate its nucleocytoplasmic shuttling. Strikingly, the STRADbeta, isoform which differs from STRADalpha in the N- and C-terminal domains that are responsible for interaction with export receptors, does not efficiently relocalize LKB1 from the nucleus to the cytoplasm. These results identify a multifactored mechanism to control LKB1 localization, and they suggest that the STRADbeta-LKB1 complex might possess unique functions in the nucleus.

  7. Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

    Science.gov (United States)

    Ptasinska, Anetta; Assi, Salam A; Martinez-Soria, Natalia; Imperato, Maria Rosaria; Piper, Jason; Cauchy, Pierre; Pickin, Anna; James, Sally R; Hoogenkamp, Maarten; Williamson, Dan; Wu, Mengchu; Tenen, Daniel G; Ott, Sascha; Westhead, David R; Cockerill, Peter N; Heidenreich, Olaf; Bonifer, Constanze

    2014-09-25

    Oncogenic transcription factors such as RUNX1/ETO, which is generated by the chromosomal translocation t(8;21), subvert normal blood cell development by impairing differentiation and driving malignant self-renewal. Here, we use digital footprinting and chromatin immunoprecipitation sequencing (ChIP-seq) to identify the core RUNX1/ETO-responsive transcriptional network of t(8;21) cells. We show that the transcriptional program underlying leukemic propagation is regulated by a dynamic equilibrium between RUNX1/ETO and RUNX1 complexes, which bind to identical DNA sites in a mutually exclusive fashion. Perturbation of this equilibrium in t(8;21) cells by RUNX1/ETO depletion leads to a global redistribution of transcription factor complexes within preexisting open chromatin, resulting in the formation of a transcriptional network that drives myeloid differentiation. Our work demonstrates on a genome-wide level that the extent of impaired myeloid differentiation in t(8;21) is controlled by the dynamic balance between RUNX1/ETO and RUNX1 activities through the repression of transcription factors that drive differentiation.

  8. Identification of a Dynamic Core Transcriptional Network in t(8;21 AML that Regulates Differentiation Block and Self-Renewal

    Directory of Open Access Journals (Sweden)

    Anetta Ptasinska

    2014-09-01

    Full Text Available Oncogenic transcription factors such as RUNX1/ETO, which is generated by the chromosomal translocation t(8;21, subvert normal blood cell development by impairing differentiation and driving malignant self-renewal. Here, we use digital footprinting and chromatin immunoprecipitation sequencing (ChIP-seq to identify the core RUNX1/ETO-responsive transcriptional network of t(8;21 cells. We show that the transcriptional program underlying leukemic propagation is regulated by a dynamic equilibrium between RUNX1/ETO and RUNX1 complexes, which bind to identical DNA sites in a mutually exclusive fashion. Perturbation of this equilibrium in t(8;21 cells by RUNX1/ETO depletion leads to a global redistribution of transcription factor complexes within preexisting open chromatin, resulting in the formation of a transcriptional network that drives myeloid differentiation. Our work demonstrates on a genome-wide level that the extent of impaired myeloid differentiation in t(8;21 is controlled by the dynamic balance between RUNX1/ETO and RUNX1 activities through the repression of transcription factors that drive differentiation.

  9. 42 CFR 440.315 - Exempt individuals.

    Science.gov (United States)

    2010-10-01

    ...) MEDICAL ASSISTANCE PROGRAMS SERVICES: GENERAL PROVISIONS Benchmark Benefit and Benchmark-Equivalent... exempt from mandatory enrollment in benchmark or benchmark-equivalent coverage. (a) The individual is...

  10. NORM regulations

    Energy Technology Data Exchange (ETDEWEB)

    Gray, P. [ed.

    1997-02-01

    The author reviews the question of regulation for naturally occuring radioactive material (NORM), and the factors that have made this a more prominent concern today. Past practices have been very relaxed, and have often involved very poor records, the involvment of contractors, and the disposition of contaminated equipment back into commercial service. The rationale behind the establishment of regulations is to provide worker protection, to exempt low risk materials, to aid in scrap recycling, to provide direction for remediation and to examine disposal options. The author reviews existing regulations at federal and state levels, impending legislation, and touches on the issue of site remediation and potential liabilities affecting the release of sites contaminated by NORM.

  11. 77 FR 38339 - Dairyland Power Cooperative, La Crosse Boiling Water Reactor Exemption From Certain Security...

    Science.gov (United States)

    2012-06-27

    ... COMMISSION Dairyland Power Cooperative, La Crosse Boiling Water Reactor Exemption From Certain Security... Dairyland Power Cooperative (DPC). The LACBWR was a nuclear power plant of nominal 50 Mw electrical output... from the regulations in part 73 as it determines are authorized by law and will not endanger life...

  12. 31 CFR 585.213 - Exemption of activities related to certain international organizations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exemption of activities related to certain international organizations. 585.213 Section 585.213 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE...

  13. 78 FR 13864 - Atlantic Highly Migratory Species; Exempted Fishing, Scientific Research, Display, and Chartering...

    Science.gov (United States)

    2013-03-01

    ... Fishing, Scientific Research, Display, and Chartering Permits; Letters of Acknowledgment AGENCY: National... received regarding our intent to issue Exempted Fishing Permits (EFPs), Scientific Research Permits (SRPs... prohibited by the regulations contained in this part for the conduct of scientific research, the...

  14. 15 CFR 30.39 - Special exemptions for shipments to the U.S. Armed Services.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Special exemptions for shipments to the U.S. Armed Services. 30.39 Section 30.39 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN TRADE...

  15. 15 CFR 30.38 - Exemption from the requirements for reporting complete commodity information.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Exemption from the requirements for reporting complete commodity information. 30.38 Section 30.38 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN...

  16. 76 FR 25236 - Carbon Dioxide; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2011-05-04

    ... AGENCY 40 CFR Part 180 Carbon Dioxide; Exemption From the Requirement of a Tolerance AGENCY... from the requirement of a tolerance for residues of carbon dioxide (CAS Reg. No. 124-38-9) when used as... permissible level for residues of carbon dioxide. DATES: This regulation is effective May 4, 2011....

  17. 76 FR 68511 - STP Nuclear Operating Company; South Texas Project, Units 1 and 2; Exemption

    Science.gov (United States)

    2011-11-04

    ... systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR part 50, ``ECCS Evaluation... regulations presume the use of zircaloy or ZIRLO \\TM\\ fuel rod cladding. Thus, an exemption from the requirements of 10 CFR 50.46 and Appendix K is needed to support the use of a different fuel rod...

  18. 76 FR 55422 - Indiana Michigan Power Company; Donald C. Cook Nuclear Plant, Unit 1; Exemption

    Science.gov (United States)

    2011-09-07

    ... systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR part 50, ``ECCS Evaluation... written, the regulations presume the use of zircaloy or ZIRLO\\TM\\ fuel rod cladding. Thus, an exemption... Optimized ZIRLO\\TM\\ fuel rod cladding at CNP-1. 3.0 Discussion Pursuant to 10 CFR 50.12, the Commission...

  19. 75 FR 13142 - Florida Power and Light Company; Turkey Point, Units 3 and 4; Exemption

    Science.gov (United States)

    2010-03-18

    ... using Framatome Advanced Nuclear Power Topical Report (TR) BAW-2308, Revisions 1A and 2A, ``Initial RT NDT of Linde 80 Weld Materials.'' This exemption addresses only those parts of the regulations (i.e...-ductility reference temperature, RT NDT(U), and its associated uncertainty, . All other requirements of...

  20. 76 FR 55255 - Definition of Solid Waste Disposal Facilities for Tax-Exempt Bond Purposes; Correction

    Science.gov (United States)

    2011-09-07

    ... Internal Revenue Service 26 CFR Part 1 RIN 1545-BD04 Definition of Solid Waste Disposal Facilities for Tax... the Federal Register on Friday, August 19, 2011, on the definition of solid waste disposal facilities... regulations provide guidance to State and local governments that issue tax-exempt bonds to finance solid...

  1. 76 FR 43847 - Poison Prevention Packaging Requirements; Exemption of Powder Formulations of Colesevelam...

    Science.gov (United States)

    2011-07-22

    ... COMMISSION 16 CFR Part 1700 Poison Prevention Packaging Requirements; Exemption of Powder Formulations of...) 504-7300; jboja@cpsc.gov . SUPPLEMENTARY INFORMATION: A. Background 1. The Poison Prevention Packaging Act of 1970 and Implementing Regulations The Poison Prevention Packaging Act of 1970 (``PPPA''), 15...

  2. 77 FR 58977 - Exempting In-Home Video Telehealth From Copayments

    Science.gov (United States)

    2012-09-25

    ... inpatient hospital care or outpatient medical care. Specifically, the regulation exempted in-home video telehealth care from having any required copayment. VA received no significant adverse comments concerning... FR 13195 on the same date. The direct final rule and proposed rule each provided a 30-day...

  3. 17 CFR 450.3 - Exemption for holdings subject to fiduciary standards.

    Science.gov (United States)

    2010-04-01

    ... TREASURY REGULATIONS UNDER TITLE II OF THE GOVERNMENT SECURITIES ACT OF 1986 CUSTODIAL HOLDINGS OF GOVERNMENT SECURITIES BY DEPOSITORY INSTITUTIONS § 450.3 Exemption for holdings subject to fiduciary... the Office of Thrift Supervision governing the holding of government securities in a...

  4. 29 CFR 4902.11 - Specific exemptions: Office of Inspector General Investigative File System.

    Science.gov (United States)

    2010-07-01

    ... Investigative File System. 4902.11 Section 4902.11 Labor Regulations Relating to Labor (Continued) PENSION... General Investigative File System. (a) Criminal Law Enforcement. (1) Exemption. Under the authority... Inspector General Investigative File System—PBGC” from the provisions of 5 U.S.C. 552a (c)(3), (c)(4),...

  5. 75 FR 5887 - Listing of Color Additives Exempt From Certification; Astaxanthin Dimethyldisuccinate...

    Science.gov (United States)

    2010-02-05

    ... Color Additives Exempt From Certification; Astaxanthin Dimethyldisuccinate; Confirmation of Effective... color additive regulations to provide for the safe use of astaxanthin dimethyldisuccinate as a color... astaxanthin dimethyldisuccinate as a color additive in the feed of salmonid fish to enhance the color of...

  6. 75 FR 10186 - Beauveria bassiana HF23; Amendment of Exemption from the Requirement of a Tolerance

    Science.gov (United States)

    2010-03-05

    ... [Federal Register Volume 75, Number 43 (Friday, March 5, 2010)] [Rules and Regulations] [Pages 10186-10190] [FR Doc No: 2010-4544] ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 180 [EPA-HQ-OPP-2005-0316; FRL-8814-6] Beauveria bassiana HF23; Amendment of Exemption from the Requirement of a...

  7. 17 CFR 250.11 - Certain acquisitions by affiliates exempted from section 9(a)(2).

    Science.gov (United States)

    2010-04-01

    ... United States: Provided, That the acquiring company is not an affiliate under section 2(a)(11)(A) of the... AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, PUBLIC UTILITY HOLDING COMPANY ACT... section 9(a)(2). (a) Acquisitions by certain exempt holding companies. Any holding company which is...

  8. 75 FR 9958 - Carolina Power & Light Company, Shearon Harris Nuclear Power Plant, Unit 1; Exemption

    Science.gov (United States)

    2010-03-04

    ... COMMISSION Carolina Power & Light Company, Shearon Harris Nuclear Power Plant, Unit 1; Exemption 1.0... of the Shearon Harris Nuclear Power Plant, Unit 1 (HNP). The license provides, among other things... operating nuclear power plants, but noted that the Commission's regulations provide mechanisms...

  9. 75 FR 5887 - Listing of Color Additives Exempt From Certification; Paracoccus Pigment; Confirmation of...

    Science.gov (United States)

    2010-02-05

    ... Color Additives Exempt From Certification; Paracoccus Pigment; Confirmation of Effective Date AGENCY... rule that appeared in the Federal Register of November 16, 2009. The final rule amended the color additive regulations to provide for the safe use of paracoccus pigment as a color additive in the feed...

  10. 75 FR 34360 - Listing of Color Additives Exempt From Certification; Bismuth Citrate; Confirmation of Effective...

    Science.gov (United States)

    2010-06-17

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Listing of Color Additives Exempt From... March 26, 2010. The final rule amended the color additive regulations by increasing the permitted use level of bismuth citrate as a color additive in cosmetics intended for coloring hair on the scalp....

  11. 76 FR 59503 - Listing of Color Additives Exempt From Certification; Reactive Blue 69; Confirmation of Effective...

    Science.gov (United States)

    2011-09-27

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Listing of Color Additives Exempt From... May 4, 2011 (76 FR 25234). The final rule amended the color additive regulations to provide for the...-sulphonate (CAS Reg. No. 70209-99- 3), also known as Reactive Blue 69, as a color additive in contact...

  12. Endurance training blocks uncoupling protein 1 up-regulation in brown adipose tissue while increasing uncoupling protein 3 in the muscle tissue of rats fed with a high-sugar diet.

    Science.gov (United States)

    de Queiroz, Karina Barbosa; Rodovalho, Gisele Vieira; Guimarães, Juliana Bohnen; de Lima, Daniel Carvalho; Coimbra, Cândido Celso; Evangelista, Elísio Alberto; Guerra-Sá, Renata

    2012-09-01

    The mitochondrial uncoupling proteins (UCPs) of interscapular brown adipose tissue (iBAT) and of muscles play important roles in energy balance. For instance, the expression of UCP1 and UCP3 are modulated by free fatty acid gradients induced by high-sugar diets and acute exercise that is dependent on sympathetic stimulation. However, the effects of endurance training in animals fed with high-sugar diets are unknown. This study aims to evaluate the long-term effects of diet and exercise on UCP1 and UCP3 levels and energy balance efficiency. Rats fed with standard or high-sugar (HSD) diets were simultaneously subjected to running training over an 8-week period. After the training period, the rats were decapitated, and the iBAT and gastrocnemius muscle tissues were removed for evaluation of the β₃-receptor, Ucp1, and Ucp3 mRNA and protein expression, which were analyzed by quantitative reverse transcriptase polymerase chain reaction and Western blot, respectively. Groups fed with an HSD displayed a higher adiposity index and iBAT weight (P tissues. In association with an HSD, training restored the increasing β₃-receptor mRNA and greatly up-regulated the levels of Ucp3 mRNA. Therefore, training blocked the HSD-induced up-regulation of UCP1 expression in iBAT, whereas it up-regulated the expression of Ucp3 mRNA in muscle. These results suggest that training enhances the relationship between Ucp1/Ucp3 mRNA levels, which could result in higher energy efficiency, but not when HSD-induced elevated sympathetic activity is maintained.

  13. 28 CFR 16.84 - Exemption of Immigration Appeals System.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Immigration Appeals System... MATERIAL OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.84 Exemption of Immigration...) Decisions of the Board of Immigration Appeals (JUSTICE/BIA-001). This exemption applies only to the...

  14. 76 FR 8809 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-02-15

    ...-2008-0231; FMCSA-2008-0340; FMCSA-2008-0266] Qualification of Drivers; Exemption Applications; Vision...; request for comments. SUMMARY: FMCSA announces its decision to renew the exemptions from the vision... to exempt individuals from the vision requirement if the exemptions granted will not...

  15. 40 CFR 166.49 - Public notice of crisis exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Public notice of crisis exemptions... PROGRAMS EXEMPTION OF FEDERAL AND STATE AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Crisis Exemptions § 166.49 Public notice of crisis exemptions. (a) Periodic notices. At least quarterly,...

  16. 7 CFR 900.700 - Exemption from assessments.

    Science.gov (United States)

    2010-01-01

    ... assessment exemption, the committee or board will approve the exemption and notify the applicant, in writing... notification of approval of the assessment exemption, in writing, by the committee or board. ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exemption from assessments. 900.700 Section...

  17. 29 CFR 793.20 - Exclusive engagement in exempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exclusive engagement in exempt work. 793.20 Section 793.20... LABOR STANDARDS ACT Workweek Application of Exemption § 793.20 Exclusive engagement in exempt work. An employee who engages exclusively in a workweek in work which is exempt under section 13(b)(9) is...

  18. 75 FR 1453 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-01-11

    ...-2007-27897; FMCSA- 2007-28695; FMCSA-2007-29019] Qualification of Drivers; Exemption Renewals; Vision.... SUMMARY: FMCSA previously announced its decision to renew the exemptions from the vision requirement in... exempt individuals from the vision requirement if the exemptions granted will not compromise safety....

  19. 7 CFR 301.80-2b - Exempted articles. 1

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Exempted articles. 1 301.80-2b Section 301.80-2b....80-2b Exempted articles. 1 1 The articles hereby exempted remain subject to applicable restrictions under other quarantines. (a) The following articles are exempt from the certification and permit...

  20. Total Spinal Block after Thoracic Paravertebral Block.

    Science.gov (United States)

    Beyaz, Serbülent Gökhan; Özocak, Hande; Ergönenç, Tolga; Erdem, Ali Fuat; Palabıyık, Onur

    2014-02-01

    Thoracic paravertebral block (TPVB) can be performed with or without general anaesthesia for various surgical procedures. TPVB is a popular anaesthetic technique due to its low side effect profile and high analgesic potency. We used 20 mL of 0.5% levobupivacaine for a single injection of unilateral TPVB at the T7 level with neurostimulator in a 63 year old patient with co-morbid disease who underwent cholecystectomy. Following the application patient lost consciousness, and was intubated. Haemodynamic instability was normalised with rapid volume replacement and vasopressors. Anaesthetic drugs were stopped at the end of the surgery and muscle relaxant was antagonised. Return of mucle strenght was shown with neuromuscular block monitoring. Approximately three hours after TPVB, spontaneous breathing started and consciousness returned. A total spinal block is a rare and life-threatening complication. A total spinal block is a complication of spinal anaesthesia, and it can also occur after peripheral blocks. Clinical presentation is characterised by hypotension, bradicardia, apnea, and cardiac arrest. An early diagnosis and appropriate treatment is life saving. In this case report, we want to present total spinal block after TPVB.

  1. Medical devices; exemption from premarket notification; class II devices; wheelchair elevator. Final order.

    Science.gov (United States)

    2013-03-04

    The Food and Drug Administration (FDA) is publishing an order granting a petition requesting exemption from premarket notification requirements for wheelchair elevator devices commonly known as inclined platform lifts and vertical platform lifts. These devices are used to provide a means for a person with a mobility impairment caused by injury or other disease to move from one level to another, usually in a wheelchair. This order exempts wheelchair elevators, class II devices, from premarket notification and establishes conditions for exemption for this device that will provide a reasonable assurance of the safety and effectiveness of the device without submission of a premarket notification (510(k)). This exemption from 510(k), subject to these conditions, is immediately in effect for wheelchair elevators. All other devices classified under FDA's wheelchair elevator regulations, including attendant-operated stair climbing devices for wheelchairs and portable platform lifts, continue to require submission of 510(k)s. FDA is publishing this order in accordance with the section of the Food, Drug, and Cosmetic Act (the FD&C Act) permitting the exemption of a device from the requirement to submit a 510(k).

  2. 40 CFR 211.110 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Exemptions. 211.110 Section 211.110 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS PRODUCT NOISE LABELING General Provisions § 211.110 Exemptions....

  3. 50 CFR 17.7 - Raptor exemption.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 2 2010-10-01 2010-10-01 false Raptor exemption. 17.7 Section 17.7....7 Raptor exemption. (a) The prohibitions found in §§ 17.21 and 17.31 do not apply to any raptor... the progeny of such a raptor. (b) This section does not apply to any raptor intentionally returned...

  4. 20 CFR 903.8 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Exemptions. 903.8 Section 903.8 Employees' Benefits JOINT BOARD FOR THE ENROLLMENT OF ACTUARIES ACCESS TO RECORDS Records Pertaining to Individuals § 903.8 Exemptions. (a) Names of systems: (1) JBEA—Enrollment Files. (2) JBEA—Application Files....

  5. 40 CFR 87.7 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM AIRCRAFT AND AIRCRAFT ENGINES General Provisions § 87.7 Exemptions. (a) Exemptions based on... among all economically competing parties. (4) Public health and welfare effects. (5) Other factors...

  6. 14 CFR 34.7 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES General Provisions § 34.7 Exemptions... durations at infrequent intervals. The emission standards of this part do not apply to engines which power... determination shall be made before the flight takes place. (b) Exemptions for very low production engine...

  7. 20 CFR 363.4 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Exemptions. 363.4 Section 363.4 Employees' Benefits RAILROAD RETIREMENT BOARD INTERNAL ADMINISTRATION, POLICY AND PROCEDURES GARNISHMENT OF REMUNERATION OF BOARD PERSONNEL § 363.4 Exemptions. (a) The portion of any payment due to a Board...

  8. 32 CFR 324.7 - Exemption rules.

    Science.gov (United States)

    2010-07-01

    ... exemption rule, claimed by the Defense Finance and Accounting Service under authority of 5 U.S.C. 552a(k)(1... for classified records. Any record in a system of records maintained by the Defense Finance and Accounting Service which falls within the provisions of 5 U.S.C. 552a(k)(1) may be exempt from the...

  9. 32 CFR 701.113 - PA exemptions.

    Science.gov (United States)

    2010-07-01

    ... access to their records. (ii) “(j)(2)”—this exemption protects criminal law enforcement records... performs, as one of its principal functions, the enforcement of criminal laws. For example, the Naval Criminal Investigative Service and military police activities qualify for this exemption. Criminal...

  10. Reasons Parents Exempt Children from Receiving Immunizations

    Science.gov (United States)

    Luthy, Karlen E.; Beckstrand, Renea L.; Callister, Lynn C.; Cahoon, Spencer

    2012-01-01

    School nurses are on the front lines of educational efforts to promote childhood vaccinations. However, some parents still choose to exempt their children from receiving vaccinations for personal reasons. Studying the beliefs of parents who exempt vaccinations allows health care workers, including school nurses, to better understand parental…

  11. 12 CFR 604.420 - Exemptive provisions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Exemptive provisions. 604.420 Section 604.420 Banks and Banking FARM CREDIT ADMINISTRATION ADMINISTRATIVE PROVISIONS FARM CREDIT ADMINISTRATION BOARD... Farm Credit Administration; (c) Disclose matters specifically exempted from disclosure by...

  12. 47 CFR 15.103 - Exempted devices.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Exempted devices. 15.103 Section 15.103 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Unintentional Radiators § 15.103 Exempted devices. The following devices are subject only to the general conditions of operation in §§...

  13. Generalized Block Failure

    DEFF Research Database (Denmark)

    Jönsson, Jeppe

    2015-01-01

    Block tearing is considered in several codes as a pure block tension or a pure block shear failure mechanism. However in many situations the load acts eccentrically and involves the transfer of a substantial moment in combination with the shear force and perhaps a normal force. A literature study...... yield lines around the block leads to simple interaction formulas similar to other interaction formulas in the codes.......Block tearing is considered in several codes as a pure block tension or a pure block shear failure mechanism. However in many situations the load acts eccentrically and involves the transfer of a substantial moment in combination with the shear force and perhaps a normal force. A literature study...

  14. BLOCK H-MATRICES AND SPECTRUM OF BLOCK MATRICES

    Institute of Scientific and Technical Information of China (English)

    黄廷祝; 黎稳

    2002-01-01

    The block H-matrices are studied by the concept of G-functions, several concepts of block matrices are introduced. Equivalent characters of block H-matrices are obtained. Spectrum localizations claracterized by Gfunctions for block matrices are got.

  15. Block TERM factorization of block matrices

    Institute of Scientific and Technical Information of China (English)

    SHE Yiyuan; HAO Pengwei

    2004-01-01

    Reversible integer mapping (or integer transform) is a useful way to realize Iossless coding, and this technique has been used for multi-component image compression in the new international image compression standard JPEG 2000. For any nonsingular linear transform of finite dimension, its integer transform can be implemented by factorizing the transform matrix into 3 triangular elementary reversible matrices (TERMs) or a series of single-row elementary reversible matrices (SERMs). To speed up and parallelize integer transforms, we study block TERM and SERM factorizations in this paper. First, to guarantee flexible scaling manners, the classical determinant (det) is generalized to a matrix function, DET, which is shown to have many important properties analogous to those of det. Then based on DET, a generic block TERM factorization,BLUS, is presented for any nonsingular block matrix. Our conclusions can cover the early optimal point factorizations and provide an efficient way to implement integer transforms for large matrices.

  16. Lesson Thirteen Trifascicular Block

    Institute of Scientific and Technical Information of China (English)

    鲁端; 王劲

    2005-01-01

    @@ A complete trifascicular block would result in complete AV block. The idio ventricular rhythm has a slower rate and a wide QRS complex because the pacemaker is located at the peripheral part of the conduction system distal to the sites of the block1. Such a rhythm may be difficult to differentiate from bifascicular or bundle branch block combined with complete block at a higher level such as the AV node or His bundle2. Besides a slower ventricular rate, a change in the morphology of the QRS complex from a previous known bifascicular pattern would be strongly suggestive of a trifascicular origin of the complete AV block3. A His bundle recording is required for a definitive diagnosis, however.

  17. Blocked Urethral Valves

    Science.gov (United States)

    ... Blocked Urethral Valves Health Issues Listen Español Text Size Email Print Share Blocked Urethral Valves Page Content Article Body Urine leaves the bladder through a tube called the urethra, which in boys passes through the penis. Rarely, small membranes form across the urethra in ...

  18. Types of Heart Block

    Science.gov (United States)

    ... P wave as it normally would. If an electrical signal is blocked before it reaches the ventricles, they won't contract and pump blood to the lungs and the rest of the body. Second-degree heart block is divided into two ...

  19. Related Drupal Nodes Block

    NARCIS (Netherlands)

    Van der Vegt, Wim

    2010-01-01

    Related Drupal Nodes Block This module exposes a block that uses Latent Semantic Analysis (Lsa) internally to suggest three nodes that are relevant to the node a user is viewing. This module performs three tasks. 1) It periodically indexes a Drupal site and generates a Lsa Term Document Matrix. Inde

  20. The Block Neighborhood

    CERN Document Server

    Arrighi, Pablo

    2010-01-01

    We define the block neighborhood of a reversible CA, which is related both to its decomposition into a product of block permutations and to quantum computing. We give a purely combinatorial characterization of the block neighborhood, which helps in two ways. First, it makes the computation of the block neighborhood of a given CA relatively easy. Second, it allows us to derive upper bounds on the block neighborhood: for a single CA as function of the classical and inverse neighborhoods, and for the composition of several CAs. One consequence of that is a characterization of a class of "elementary" CAs that cannot be written as the composition of two simpler parts whose neighborhoods and inverse neighborhoods would be reduced by one half.

  1. The Institutionalised and Non-Institutionalised Exemptions from EU Public Procurement Law: Towards a More Coherent Approach?

    Directory of Open Access Journals (Sweden)

    Willem A. Janssen

    2014-12-01

    Full Text Available From a EU public procurement law perspective, contracting authorities have a discretionary power to decide upon who is allowed and best suited to provide public services to the public. When public authorities deem the in-house performance of a service to be the most suitable, the Court of Justice of the EU has allowed these authorities to rely on the institutionalised and non-institutionalised exemptions, which exempt a possible duty to contract out a public contract. The first part of this contribution discusses the recent codification of these exemptions in Article 12 Directive 2014/24/EU on public procurement. It concludes that this codification creates some legal certainty, but it mostly expands the scope of these exemptions from public procurement law. The second part of this contribution proposes a more coherent approach for these exemptions by discussing the challenges of regulating and enforcing the pre-procurement phase (the make-or-buy decision in which a public authority decides to favour the internal or external performance of a service. It concludes by providing legal perspectives to regulate and enforce this decision-making phase.

  2. 40 CFR 92.804 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Importation of Nonconforming Locomotives and Locomotive..., and that enter the United States temporarily from Canada or Mexico are exempt from the...

  3. 12 CFR 22.4 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... State-owned property covered under a policy of self-insurance satisfactory to the Director of FEMA, who publishes and periodically revises the list of States falling within this exemption; or (b)...

  4. 32 CFR 322.6 - Establishing exemptions.

    Science.gov (United States)

    2010-07-01

    ...; subjects of an investigation of an actual or potential criminal or civil violation will not be alerted to...) (k)(4) exemption. Records maintained solely for statistical research or program evaluation...

  5. 12 CFR 226.29 - State exemptions.

    Science.gov (United States)

    2010-01-01

    ... Federal law; and (2) There is adequate provision for enforcement. (b) Civil liability. (1) No exemptions granted under this section shall extend to the civil liability provisions of sections 130 and 131 of...

  6. Spheres of Exemption, Figures of Exclusion

    DEFF Research Database (Denmark)

    , the history of ideas, social science, political science and literature studies, Spheres of Exemption, Figures of Exclusion offers thirteen investigations into the co-constitutive relationship between subjectivity and political and legal order, combining theoretical reflection with empirical and historical...

  7. 75 FR 4623 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-01-28

    ... the 27 exemption applications, FMCSA exempts Teddy S. Bioni, John K. Butler, James J. Coffield, Roy E.... Kool, Curtis M. Lawless, Michael E. Lindquist, Philip J.C. Locke, Travis J. Luce, Cameron S....

  8. 28 CFR 36.404 - Alterations: Elevator exemption.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Alterations: Elevator exemption. 36.404... Alterations: Elevator exemption. (a) This section does not require the installation of an elevator in an... facility has an elevator....

  9. 77 FR 541 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-01-05

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision.... SUMMARY: FMCSA announces its decision to exempt seven individuals from the vision requirement in the... commercial motor vehicles (CMVs) in interstate commerce without meeting the prescribed vision...

  10. 78 FR 1927 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted,...

  11. 78 FR 1923 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted,...

  12. 78 FR 1926 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... notice of receipt of Federal diabetes exemption applications from 12 individuals and requested...

  13. 78 FR 79062 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-27

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  14. 78 FR 50486 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  15. 78 FR 20381 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-04

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  16. 78 FR 26419 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  17. 78 FR 63295 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  18. 76 FR 21792 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-04-18

    ... for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  19. 78 FR 24795 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-26

    ... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  20. 78 FR 65034 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  1. 75 FR 34206 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-06-16

    ... exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  2. 75 FR 63536 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-10-15

    ... exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  3. 77 FR 33554 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-06

    ... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  4. 78 FR 56988 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-16

    ... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications...

  5. 78 FR 63280 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  6. 78 FR 64267 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-28

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... diabetes mellitus, and be consistent with the criteria described in section 4018 of the Transportation... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  7. 77 FR 74271 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-13

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  8. 78 FR 63285 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  9. 77 FR 27842 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-05-11

    ... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications...

  10. 78 FR 63298 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  11. 76 FR 1499 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-01-10

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision.... SUMMARY: FMCSA announces its decision to exempt 15 individuals from the vision requirement in the Federal... commercial motor vehicles (CMVs) in interstate commerce without meeting the prescribed vision standard....

  12. 75 FR 3053 - Application Numbers and Proposed Exemptions

    Science.gov (United States)

    2010-01-19

    ... Labor Employee Benefits Security Administration Application Numbers and Proposed Exemptions; Notice #0... LABOR Employee Benefits Security Administration Application Numbers and Proposed Exemptions AGENCY... Notice. Comments and requests for a hearing should state: (1) The name, address, and telephone number...

  13. 29 CFR 780.3 - Exemptions discussed in this part.

    Science.gov (United States)

    2010-07-01

    ... industry are discussed in this part 780. These exemptions differ substantially in their terms, scope, and...) exemption (cotton ginning and sugar processing) discussed in subpart I of this part, and the section...

  14. 29 CFR 553.32 - Other FLSA exemptions.

    Science.gov (United States)

    2010-07-01

    ... Act provides a minimum wage and overtime pay exemption for any employee employed by an amusement or... local governments operate parks and recreational areas to which this exemption may apply. (f) Section...

  15. Block copolymer battery separator

    Science.gov (United States)

    Wong, David; Balsara, Nitash Pervez

    2016-04-26

    The invention herein described is the use of a block copolymer/homopolymer blend for creating nanoporous materials for transport applications. Specifically, this is demonstrated by using the block copolymer poly(styrene-block-ethylene-block-styrene) (SES) and blending it with homopolymer polystyrene (PS). After blending the polymers, a film is cast, and the film is submerged in tetrahydrofuran, which removes the PS. This creates a nanoporous polymer film, whereby the holes are lined with PS. Control of morphology of the system is achieved by manipulating the amount of PS added and the relative size of the PS added. The porous nature of these films was demonstrated by measuring the ionic conductivity in a traditional battery electrolyte, 1M LiPF.sub.6 in EC/DEC (1:1 v/v) using AC impedance spectroscopy and comparing these results to commercially available battery separators.

  16. Hawaii Census 2000 Blocks

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer represents Census 2000 demographic data derived from the PL94-171 redistricting files and SF3. Census geographic entities include blocks, blockgroups...

  17. Steroidal neuromuscular blocking agents

    NARCIS (Netherlands)

    Wierda, JMKH; Mori, K; Ohmura, A; Toyooka, H; Hatano, Y; Shingu, K; Fukuda, K

    1998-01-01

    Since 1964 approximately 20 steroidal neuromuscular blocking agents have been evaluated clinically. Pancuronium, a bisquaternary compound designed on the drawingboard, was the first steroidal relaxant introduced into clinical practice worldwide in the 1970's. Although a major improvement, pancuroniu

  18. Superalloy Lattice Block Structures

    Science.gov (United States)

    Nathal, M. V.; Whittenberger, J. D.; Hebsur, M. G.; Kantzos, P. T.; Krause, D. L.

    2004-01-01

    Initial investigations of investment cast superalloy lattice block suggest that this technology will yield a low cost approach to utilize the high temperature strength and environmental resistance of superalloys in lightweight, damage tolerant structural configurations. Work to date has demonstrated that relatively large superalloy lattice block panels can be successfully investment cast from both IN-718 and Mar-M247. These castings exhibited mechanical properties consistent with the strength of the same superalloys measured from more conventional castings. The lattice block structure also accommodates significant deformation without failure, and is defect tolerant in fatigue. The potential of lattice block structures opens new opportunities for the use of superalloys in future generations of aircraft applications that demand strength and environmental resistance at elevated temperatures along with low weight.

  19. 15 CFR 30.40 - Special exemptions for certain shipments to U.S. government agencies and employees.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Special exemptions for certain shipments to U.S. government agencies and employees. 30.40 Section 30.40 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE FOREIGN...

  20. 75 FR 60411 - Request for Comment on Options for a Proposed Exemptive Order Relating to the Trading and...

    Science.gov (United States)

    2010-09-30

    ... regulated markets. 2. Efficiency, competition, and financial integrity. The options for a proposed exemption may enhance market efficiency and competition since they could encourage potential trading of options... discovery may be enhanced through market competition. 4. Sound risk management practices. The options...

  1. 77 FR 40142 - Applications for Exemption: Commercial Driver's License (CDL) and Hours-of-Service (HOS) of Drivers

    Science.gov (United States)

    2012-07-06

    ... May 21, 2012, and of Underwater Construction Corporation (Underwater) on May 29, 2012. On June 4, 2012....regulations.gov at any time, or to Room W12-140, DOT Building, 1200 New Jersey Ave. SE., Washington, DC... the case with the denials announced today. Applications for Exemption Rotel, Underwater,...

  2. 75 FR 32230 - Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Science.gov (United States)

    2010-06-07

    ... ADMINISTRATION Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd... Small Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). Solutions Capital I,...

  3. 77 FR 11618 - Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Science.gov (United States)

    2012-02-27

    ... ADMINISTRATION Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd., Suite 3000... Administration Rules and Regulations (13 CFR 107). Solutions Capital I, L.P., proposes to acquire debt...

  4. 29 CFR 780.815 - Basic conditions of exemption; second part, processing of sugar beets, sugar-beet molasses...

    Science.gov (United States)

    2010-07-01

    ... sugar beets, sugar-beet molasses, sugarcane, or maple sap. 780.815 Section 780.815 Labor Regulations... Cotton and Processing of Sugar Beets, Sugar-Beet Molasses, Sugarcane, or Maple Sap into Sugar or Syrup... Quantities § 780.815 Basic conditions of exemption; second part, processing of sugar beets,...

  5. 77 FR 27140 - Privacy Act of 1974: Implementation of Exemptions; Export-Import Bank of the United States Office...

    Science.gov (United States)

    2012-05-09

    ... processing allegations of violation of criminal, civil, and administrative laws and regulations relating to... General Investigative Records (a) Criminal Law Enforcement. (1) Exemption. Under the authority granted by... information pertaining to the enforcement of criminal laws. ``EIB-35--Office of Inspector...

  6. 76 FR 71619 - Parts and Accessories Necessary for Safe Operation; Grant of Temporary Exemption for Con-way...

    Science.gov (United States)

    2011-11-18

    ... video event recorders to improve driver behavior will improve the overall level of safety to the... the Agency's regulations. The lane departure warning system ] alerts drivers who unintentionally drift... exemption from the prohibition on obstructions to the driver's field of view requirements in 49 CFR...

  7. 78 FR 53051 - Ethyl-2E,4Z-Decadienoate (Pear Ester); Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2013-08-28

    ... AGENCY 40 CFR Part 180 Ethyl-2E,4Z-Decadienoate (Pear Ester); Exemption From the Requirement of a...-2E,4Z- decadienoate (pear ester) in or on all food commodities. This regulation eliminates the need to establish a maximum permissible level for residues of ethyl-2E,4Z-decadienoate (pear ester)....

  8. 75 FR 6414 - Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Science.gov (United States)

    2010-02-09

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment... Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). Cardinal Growth, L.P....

  9. 78 FR 57444 - Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts...

    Science.gov (United States)

    2013-09-18

    ... ADMINISTRATION Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III, L.P., 101 S. Hanley Road, Suite 1250, St... Business Administration (``SBA'') Rules and Regulations. Eagle Fund III, L.P., provided debt and...

  10. 78 FR 57444 - Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Science.gov (United States)

    2013-09-18

    ... ADMINISTRATION Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III-A, L.P., 101 S. Hanley Road, Suite 1250, St... Business Administration (``SBA'') Rules and Regulations. Eagle Fund III-A, L.P., provided debt and...

  11. 78 FR 42451 - Listing of Color Additives Exempt From Certification; Reactive Blue 246 and Reactive Blue 247...

    Science.gov (United States)

    2013-07-16

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Listing of Color Additives Exempt From... color additive regulations in Sec. Sec. 73.3100 and 73.3106 (21 CFR 73.3100 and 73.3106), respectively... Blue 246), as color additives in contact lenses. We also corrected the nomenclature for Reactive...

  12. 7 CFR 980.501 - Safeguard procedures for potatoes, onions, and tomatoes exempt from grade, size, quality, and...

    Science.gov (United States)

    2010-01-01

    ... “Importer's Exempt Commodity Form” to the U.S. Customs Service Regional Director or District Director, as... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... relief agencies; (2) Potatoes, onions, or tomatoes for processing; (3) Potatoes or onions for...

  13. 7 CFR 999.500 - Safeguard procedures for walnuts and certain dates exempt from grade, size, quality, and maturity...

    Science.gov (United States)

    2010-01-01

    ... completed “Importer's Exempt Commodity Form” to the U.S. Customs Service Regional Director or District... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... by charitable institutions, relief agencies, governmental agencies for school lunch programs,...

  14. 26 CFR 54.4975-7 - Other statutory exemptions.

    Science.gov (United States)

    2010-04-01

    ... example, in the interest of certain selling shareholders. (3) Primary benefit requirement—(i) In general... current exempt loan. No person entitled to payment under the exempt loan shall have any right to assets of...) Right of first refusal. Qualifying employer securities acquired with proceeds of an exempt loan may,...

  15. 40 CFR 85.1704 - Who may request an exemption.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...) Any manufacturer may request a national security exemption under § 85.1708. (c) For manufacturers, vehicles or engines for export purposes are exempt without application, subject to the provisions of §...

  16. 40 CFR 85.1511 - Exemptions and exclusions.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Importation of Motor Vehicles and Motor Vehicle... exemptions or exclusions are permitted by this paragraph: (1) National security exemption. Vehicles may be imported under the national security exemption found at 40 CFR 85.1708. Only persons who are...

  17. 40 CFR 85.1706 - Pre-certification exemption.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Exclusion and Exemption of Motor Vehicles and Motor...) or (4), is exempt from section 203(a), without application, if the manufacturer complies with the... the label. (b) Any manufacturer that desires a pre-certification exemption and is in the business...

  18. 77 FR 17107 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-03-23

    ... (KY) Travis J. Luce (MI) Jack D. Miller (OH) Eric M. Moats, Sr. (MD) Robert W. Nicks (NY) Joseph S... has statutory authority to exempt individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency has concluded that granting these exemption renewals...

  19. 22 CFR 505.13 - General exemptions (Subsection (j)).

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true General exemptions (Subsection (j)). 505.13... exemptions (Subsection (j)). (a) General exemptions are available for systems of records which are maintained by the Central Intelligence Agency (Subsection (j)(1)), or maintained by an agency which performs...

  20. 76 FR 50318 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-08-12

    ... the 17 exemption applications, FMCSA exempts, Danny F. Burnley, Bruce A. Cameron, Charles E. Carter... Agency has concluded that granting these exemptions will provide a level of safety that is equivalent to... hours are from 8:30 a.m. to 5 p.m. Monday through Friday, except Federal holidays....

  1. 22 CFR 505.14 - Specific exemptions (Subsection (k)).

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Specific exemptions (Subsection (k)). 505.14... exemptions (Subsection (k)). The specific exemptions focus more on the nature of the records in the system of...) Subsection (k)(1). Records which are specifically authorized under criteria established under an...

  2. 77 FR 545 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-01-05

    ...; FMCSA-2007-0017] Qualification of Drivers; Exemption Applications; Vision AGENCY: Federal Motor Carrier.... SUMMARY: FMCSA announces its decision to renew the exemptions from the vision requirement in the Federal... from the vision requirement if the exemptions granted will not compromise safety. The Agency...

  3. 9 CFR 590.660 - Inspection of exempted plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of exempted plants. 590.660... Products Plants § 590.660 Inspection of exempted plants. Duly authorized representatives of the Administrator shall make such periodic inspections of exempted plants and records thereof as the...

  4. 17 CFR 36.3 - Exempt commercial markets.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Exempt commercial markets. 36... MARKETS § 36.3 Exempt commercial markets. (a) Notification. An electronic trading facility relying upon... electronic form, shall be labeled as “Notification of Operation as an Exempt Commercial Market,” and...

  5. 40 CFR 720.38 - Exemptions for test marketing.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Exemptions for test marketing. 720.38... CONTROL ACT PREMANUFACTURE NOTIFICATION Applicability § 720.38 Exemptions for test marketing. (a) Any person may apply for an exemption to manufacture or import a new chemical substance for test...

  6. 29 CFR 779.384 - May qualify as exempt establishments.

    Science.gov (United States)

    2010-07-01

    ... Establishments Motion Picture Theaters § 779.384 May qualify as exempt establishments. Section 13(a)(9) of the... employed by an establishment which is a motion picture theater.” This exemption will be applicable... part. A motion picture theater may also qualify as an exempt retail or service establishment...

  7. 75 FR 22179 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-27

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in the... individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency...

  8. 75 FR 39618 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-09

    ...-24015; FMCSA-2007-0071; FMCSA-2008-0021] Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in the... individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency...

  9. 75 FR 22178 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-27

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in the... individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency...

  10. 75 FR 27620 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-05-17

    ... Renewals; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of final disposition. SUMMARY: FMCSA previously announced its decision to renew the exemptions from the vision... to exempt individuals from the vision requirement if the exemptions granted will not...

  11. 75 FR 36778 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-06-28

    ... granted will not compromise safety. The Agency has concluded that granting these exemption renewals will.... Johnston Harry L. Jones Mearl C. Kennedy Aaron C. Lougher William F. Mack Patrick E. Martin Bennet G... exemption will be valid for two years unless rescinded earlier by FMCSA. The exemption will be rescinded...

  12. 40 CFR 91.1010 - Granting of exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Granting of exemptions. 91.1010 Section 91.1010 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Engines § 91.1010 Granting of exemptions. (a) If upon completion of the review of an exemption...

  13. 14 CFR 399.21 - Charter exemptions (except military).

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Charter exemptions (except military). 399.21 Section 399.21 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION... Authority § 399.21 Charter exemptions (except military). In deciding applications for exemptions...

  14. 75 FR 9482 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-03-02

    ... of the 33 exemption applications, FMCSA exempts, Bradley T. Alspach, William M. Arbogast, John E..., Amos W. Hulsey, Guy A. Lanham, Glenn Lewis, James M. McCormick, Shane W. Mincey, Millard F. Neace, II.... Under 49 U.S.C. 31136(e) and 31315, FMCSA may grant an exemption for a 2-year period if it finds...

  15. 40 CFR 146.4 - Criteria for exempted aquifers.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Criteria for exempted aquifers. 146.4... for exempted aquifers. An aquifer or a portion thereof which meets the criteria for an “underground source of drinking water” in § 146.3 may be determined under 40 CFR 144.8 to be an “exempted aquifer”...

  16. 7 CFR 301.85-2b - Exempted articles. 1

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Exempted articles. 1 301.85-2b Section 301.85-2b... § 301.85-2b Exempted articles. 1 1 The articles hereby exempted remain subject to applicable restrictions under other quarantines and other provisions of this subpart. (a) The following articles...

  17. Compulsory school-entry vaccination laws and exemptions: who is opting out in ontario and why does it matter?

    Science.gov (United States)

    Mah, Catherine L; Guttmann, Astrid; McGeer, Allison; Krahn, Murray; Deber, Raisa B

    2010-05-01

    School-entry vaccination regulations are a policy instrument that has been widely used in some jurisdictions as a mechanism to ensure high immunization coverage rates. Exemptions to school-entry vaccination, which can be allowed on medical or non-medical grounds, present a number of ethical and policy challenges. In this paper, we consider the situation in Canada, where school-entry vaccination laws are rare. We present newly available aggregate-level registry data from Ontario comparing the use of medical and non-medical immunization exemptions to school-entry vaccination and the implications for population health.

  18. 77 FR 61515 - Alkyl Amines Polyalkoxylates; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2012-10-10

    ...This regulation amends the exemption from the requirement of a tolerance for residues alkyl amines polyalkoxylates under 40 CFR 180.920 and 40 CFR 180.930 to include the additional Chemical Abstract Service Registry Number (CAS Reg. No.) 1266162-49-5. BASF Corporation submitted a petition to EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting an amendment to an existing......

  19. Right bundle branch block

    DEFF Research Database (Denmark)

    Bussink, Barbara E; Holst, Anders Gaarsdal; Jespersen, Lasse;

    2013-01-01

    AimsTo determine the prevalence, predictors of newly acquired, and the prognostic value of right bundle branch block (RBBB) and incomplete RBBB (IRBBB) on a resting 12-lead electrocardiogram in men and women from the general population.Methods and resultsWe followed 18 441 participants included.......5%/2.3% in women, P Right bundle branch block was associated with significantly.......60-1.62). The presence of IRBBB was not associated with any adverse outcome.ConclusionIn this cohort study, RBBB and IRBBB were two to three times more common among men than women. Right bundle branch block was associated with increased cardiovascular risk and all-cause mortality, whereas IRBBB was not. Contrary...

  20. Contaminated soil concrete blocks

    NARCIS (Netherlands)

    Korte, de A.C.J.; Brouwers, H.J.H.; Limbachiya, Mukesh C.; Kew, Hsein Y.

    2009-01-01

    According to Dutch law the contaminated soil needs to be remediated or immobilised. The main focus in this article is the design of concrete blocks, containing contaminated soil, that are suitable for large production, financial feasible and meets all technical and environmental requirements. In ord

  1. Effects of Block Scheduling

    Directory of Open Access Journals (Sweden)

    William R. Veal

    1999-09-01

    Full Text Available This study examined the effects of a tri-schedule on the academic achievement of students in a high school. The tri-schedule consists of traditional, 4x4 block, and hybrid schedules running at the same time in the same high school. Effectiveness of the schedules was determined from the state mandated test of basic skills in reading, language, and mathematics. Students who were in a particular schedule their freshman year were tested at the beginning of their sophomore year. A statistical ANCOVA test was performed using the schedule types as independent variables and cognitive skill index and GPA as covariates. For reading and language, there was no statistically significant difference in test results. There was a statistical difference mathematics-computation. Block mathematics is an ideal format for obtaining more credits in mathematics, but the block format does little for mathematics achievement and conceptual understanding. The results have content specific implications for schools, administrations, and school boards who are considering block scheduling adoption.

  2. Concrete Block Pavements

    Science.gov (United States)

    1983-03-01

    1967, Cedergren 1974, Federal Highway .’,U .. V,47 -’":: 37 Administration 1980). Block pavements have essentially the same prob- lems with moisture...Vicksburg, Miss. Cedergren , H. R. 1974. Drainage of Highway and Airfield Pavements, John Wiley and Sons, New VOk. I Cement and Concrete Association

  3. Block That Pain!

    Science.gov (United States)

    ... along with the National Institute of Dental and Craniofacial Research (NIDCR) and the National Institute of General Medical Sciences (NIGMS). This finding shows that a specific combination of two molecules can block only pain-related neurons. It holds the promise of major ...

  4. 75 FR 73137 - Order Extending Temporary Conditional Exemption for Nationally Recognized Statistical Rating...

    Science.gov (United States)

    2010-11-29

    ... COMMISSION Order Extending Temporary Conditional Exemption for Nationally Recognized Statistical Rating.... (``covered transactions'').\\3\\ The Commission is extending the temporary conditional exemption exempting... make it easier for the hired NRSRO to resist such pressure by increasing the likelihood that any...

  5. Regulation of executive compensation at nonprofit health care organizations: coming changes?

    Science.gov (United States)

    Bjork, David Albert

    2010-01-01

    Executive compensation in health care organizations, particularly tax-exempt organizations, has come under increasing scrutiny in recent years. This paper identifies the implications for tax-exempt health care organizations of recent efforts to regulate executive pay, as well as some changes that the boards of nonprofit health care providers and insurers should consider to minimize the case for further scrutiny and regulation of their executive pay practices.

  6. Recovery from blocking between outcomes.

    Science.gov (United States)

    Wheeler, Daniel S; Miller, Ralph R

    2005-10-01

    Contemporary associative learning research largely focuses on cue competition phenomena that occur when 2 cues are paired with a common outcome. Little research has been conducted to investigate similar phenomena occurring when a single cue is trained with 2 outcomes. Three conditioned lick suppression experiments with rats assessed whether treatments known to alleviate blocking between cues would also attenuate blocking between outcomes. In Experiment 1, conditioned responding recovered from blocking between outcomes when a long retention interval was interposed between training and testing. Experiment 2 obtained recovery from blocking between outcomes when the blocking outcome was extinguished after the blocking treatment. In Experiment 3, a recovery from blocking between outcomes occurred when a reminder stimulus was presented in a novel context prior to testing. Collectively, these studies demonstrate that blocking of outcomes, like blocking of cues, appears to be caused by a deficit in the expression of an acquired association.

  7. SUPERFICIAL CERVICAL PLEXUS BLOCK

    Directory of Open Access Journals (Sweden)

    Komang Mega Puspadisari

    2014-01-01

    Full Text Available Superficial cervical plexus block is one of the regional anesthesia in  neck were limited to thesuperficial fascia. Anesthesia is used to relieve pain caused either during or after the surgery iscompleted. This technique can be done by landmark or with ultrasound guiding. The midpointof posterior border of the Sternocleidomastoid was identified and the prosedure done on thatplace or on the level of cartilage cricoid.

  8. Managing access block.

    Science.gov (United States)

    Cameron, Peter; Scown, Paul; Campbell, Donald

    2002-01-01

    There is pessimism regarding the ability of the Acute Health Sector to manage access block for emergency and elective patients. Melbourne Health suffered an acute bed crisis in 2001 resulting in record ambulance diversions and emergency department (ED) delays. We conducted an observational study to reduce access block for emergency patients whilst maintaining elective throughput at Melbourne Health. This involved a clinician-led taskforce using previously proven principles for organisational change to implement 51 actions to improve patient access over a three-month period. The primary outcome measures were ambulance diversion, emergency patients waiting more than 12 hours for an inpatient bed, elective throughput and theatre cancellations. Despite a reduction in multi-day bed numbers all primary objectives were met, ambulance diversion decreased to minimal levels, 12-hour waits decreased by 40% and elective throughput was maintained. Theatre cancellations were also minimised. We conclude that access block can be improved by clinician-led implementation of proven process improvements over a short time frame. The ability to sustain change over the longer term requires further study.

  9. Exempting mental health peer support services from copayments. Direct final rule.

    Science.gov (United States)

    2014-11-28

    The Department of Veterans Affairs (VA) is taking final action to amend its regulation that sets forth the VA services that are not subject to copayment requirements for inpatient hospital care or outpatient medical care. Specifically, the regulation is amended to exempt mental health peer support services from having any required copayment. This removes a barrier that may have previously discouraged veterans from choosing to use mental health peer support services as a viable care option. VA believes that mental health peer support services are a valuable resource for veterans with mental health conditions and wants to ensure that veterans take full advantage of all resources available to them.

  10. Exempting Mental Health Peer Support Services From Copayments. Direct final rule; confirmation of effective date.

    Science.gov (United States)

    2015-11-05

    The Department of Veterans Affairs (VA) published a direct final rule amending its regulation that governs VA services that are not subject to copayment requirements for inpatient hospital care or outpatient medical care. Specifically, the regulation is amended to exempt mental health peer support services from having any required copayment. VA received no adverse comments concerning the direct final rule or its companion substantially identical proposed rule published in the Federal Register on the same date. This document confirms that the direct final rule became effective on January 27, 2015. In a companion document in this issue of the Federal Register, we are withdrawing as unnecessary the proposed rule.

  11. 27 CFR 479.33 - Special exemption.

    Science.gov (United States)

    2010-04-01

    ... EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES, AND CERTAIN OTHER FIREARMS Special (Occupational) Taxes § 479.33 Special exemption. (a) Any person required to pay special (occupational) tax under this part shall be relieved from payment of that tax if he establishes...

  12. 10 CFR 171.11 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... avoidance of interest and penalty charges. If a partial or full exemption is granted, any overpayment will... following factors: (1) Age of the reactor; (2) Number of customers in rate base; (3) Net increase in KWh cost for each customer directly related to the annual fee assessed under this part; and (4) Any...

  13. 22 CFR 503.8 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... documents even after the litigation is closed. (f) Exemption six—Clearly unwarranted invasion of personal... if disclosure would constitute a clearly unwarranted invasion of personal privacy. (1) Balancing test... withhold such information as home addresses, home telephone numbers, ages, minority group status,...

  14. 22 CFR 215.14 - Specific exemptions.

    Science.gov (United States)

    2010-04-01

    ... to 18 U.S.C. 3056; (4) Required by statute to be maintained and used solely as statistical records... exemptions, are set forth below: (1) Criminal Law Enforcement Records. If the 5 U.S.C. 552a(j)(2)...

  15. 76 FR 70896 - Polyethylene Glycol; Tolerance Exemption

    Science.gov (United States)

    2011-11-16

    ... AGENCY 40 CFR Part 180 Polyethylene Glycol; Tolerance Exemption AGENCY: Environmental Protection Agency... amu), 17,000; also known as polyethylene glycol, when used as an inert ingredient in a pesticide...(oxyethylene, minimum number average molecular weight (in amu), 17,000; also known as polyethylene...

  16. 32 CFR 326.17 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... systems will be made on a case-by-case basis. (h) QNRO-19. (1) System name: Customer Security Services..., military service, federal contracts, or access to classified information may be exempt pursuant to 5 U.S.C... principle behind this limited access is to allow disclosures except those indicated above. The decisions...

  17. 7 CFR 1215.300 - Exemption procedures.

    Science.gov (United States)

    2010-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND... processor who markets 4 million pounds or less of popcorn annually and who desires to claim an exemption...) Persons that process solely 100 percent organic products and that do not process any conventional...

  18. 39 CFR 266.9 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ...) because the systems contain information pertaining to the enforcement of criminal laws. The reasons for... the material. The reasons for exemption follow: (i) These systems contain questions and answers to... would be necessary if questions or answers were available for inspection and copying....

  19. 32 CFR 310.28 - General exemption.

    Science.gov (United States)

    2010-07-01

    ... any activity pertaining to the enforcement of criminal laws, such as the U.S. Army Criminal... criminal law enforcement process from arrest or indictment through the final release from parole... law-enforcement activities of a DoD Component. (c) To qualify for the (j)(2) exemption, the system...

  20. 21 CFR 21.61 - Exempt systems.

    Science.gov (United States)

    2010-04-01

    ... criminal law enforcement purposes, in the Food and Drug Administration Privacy Act Record Systems listed in... records compiled by the Food and Drug Administration in a criminal law enforcement investigation where the... enforcement purposes, including criminal law enforcement purposes, are exempt under 5 U.S.C. 552a(j)(2) and...

  1. 49 CFR 1507.3 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... exempt from the access provisions of subsection (d). (c) Personnel Background Investigation File System (DHS/TSA 004). The Personnel Background Investigation File System (PBIFS) (DHS/TSA 004) enables TSA to... Traveler Operations Files (DHS/TSA 015). The purpose of this system is to pre-screen and...

  2. 32 CFR 292.6 - FOIA exemptions.

    Science.gov (United States)

    2010-07-01

    ... is prohibited, and could subject the releaser to civil and criminal penalties. (g) Exemption (b)(7). Records or information compiled for the purpose of enforcing civil, criminal, or military law, including... interfere with enforcement proceedings. (2) Would deprive a person of a right to a fair trial or...

  3. 7 CFR 1219.8 - Exempt handler.

    Science.gov (United States)

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.8 Exempt... Hass avocados purchased by the person have already been subject to assessments under the Order....

  4. 7 CFR 57.100 - Specific exemptions.

    Science.gov (United States)

    2010-01-01

    ... section, the exemptions do not apply to restricted eggs when prohibited by State or local law: And... are allowed by the tolerances in the official standards for U.S. Consumer Grade B shell eggs; (b) (c... directly to a household consumer exclusively for use by such consumer and members of his household and...

  5. 46 CFR 107.413 - Exemption certificate.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Exemption certificate. 107.413 Section 107.413 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND... electrical installations) or II-2 (Construction—Fire protection, fire detection and fire extinction) of...

  6. Block Transfer Handbook: Constructing and Negotiating Block Transfer Agreements.

    Science.gov (United States)

    Finlay, Finola

    The purpose of this handbook is to provide resources for institutions or articulation committees who are engaged in the task of investigating the feasibility of block transfer agreements. Block transfer is the process whereby a block of credits is granted to students who have successfully completed a certificate, diploma, or cluster of courses…

  7. Demographic Data - MDC_Block

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — A polygon feature class of Miami-Dade Census 2000 Blocks. Census blocks are areas bounded on all sides by visible and/or invisible features shown on a map prepared...

  8. Habitat Blocks and Wildlife Corridors

    Data.gov (United States)

    Vermont Center for Geographic Information — Habitat blocks are areas of contiguous forest and other natural habitats that are unfragmented by roads, development, or agriculture. Vermonts habitat blocks are...

  9. 77 FR 8721 - Home Mortgage Disclosure (Regulation C)

    Science.gov (United States)

    2012-02-15

    ... PROTECTION 12 CFR Part 1003 RIN 3170-AA06 Home Mortgage Disclosure (Regulation C) AGENCY: Bureau of Consumer... requirements of Regulation C (Home Mortgage Disclosure) to reflect a change in the asset-size exemption... 1975, as amended (HMDA; 12 U.S.C. 2801 et seq.) requires most mortgage lenders located in...

  10. Porous block nanofiber composite filters

    Energy Technology Data Exchange (ETDEWEB)

    Ginley, David S.; Curtis, Calvin J.; Miedaner, Alexander; Weiss, Alan J.; Paddock, Arnold

    2016-08-09

    Porous block nano-fiber composite (110), a filtration system (10) and methods of using the same are disclosed. An exemplary porous block nano-fiber composite (110) includes a porous block (100) having one or more pores (200). The porous block nano-fiber composite (110) also includes a plurality of inorganic nano-fibers (211) formed within at least one of the pores (200).

  11. Properties of blocked linear systems.

    Science.gov (United States)

    Chen, Weitian; Anderson, Brian D O; Deistler, Manfred; Filler, Alexander

    2012-10-01

    This paper presents a systematic study on the properties of blocked linear systems that have resulted from blocking discrete-time linear time invariant systems. The main idea is to explore the relationship between the blocked and the unblocked systems. Existing results are reviewed and a number of important new results are derived. Focus is given particularly on the zero properties of the blocked system as no such study has been found in the literature.

  12. Appropriate schemata and building blocks

    Institute of Scientific and Technical Information of China (English)

    Yang Haijun; Li Minqiang

    2005-01-01

    Appropriate schemata as a novel concept to characterize building blocks are introduced, and then, the traits of appropriate schemata are presented. The effects of building blocks by search operators are analyzed. Hence, the experiments on RR-8X8 are employed to verify that appropriate schemata construct the building blocks. The validity of appropriate schemata and building blocks from the views of theory and practice is presented.

  13. Blocking the Hawking radiation

    DEFF Research Database (Denmark)

    Autzen, M.; Kouvaris, C.

    2014-01-01

    grows after its formation (and eventually destroys the star) instead of evaporating. The fate of the black hole is dictated by the two opposite mechanics, i.e., accretion of nuclear matter from the center of the star and Hawking radiation that tends to decrease the mass of the black hole. We study how...... the assumptions for the accretion rate can in fact affect the critical mass beyond which a black hole always grows. We also study to what extent degenerate nuclear matter can impede Hawking radiation due to the fact that emitted particles can be Pauli blocked at the core of the star....

  14. Property Blocks: Games and Activities.

    Science.gov (United States)

    Humphreys, Alan, Ed.; Dailey, Jean, Ed.

    This pamphlet describes the property blocks produced by MINNEMAST, and discusses their use in the development of thinking processes. Classification systems, including block diagrams and tree diagrams, are discussed. Sixteen classroom activities and eleven games which use the blocks are described. Suggestions to the teacher for further reading are…

  15. Tax-exempt bank loans still an option for providers.

    Science.gov (United States)

    Ostlund, Grant; Cheney, John E

    2011-07-01

    In evaluating the potential for tax-exempt bank financing, healthcare organizations should carefully consider: Pricing. Loan structure. Security requirements (such as financial covenants and default remedies).

  16. 78 FR 39184 - Privacy Act, Exempt Record System; Implementation

    Science.gov (United States)

    2013-07-01

    ..., falsification, or plagiarism in proposing, performing, or reviewing research, or in reporting research results... containing investigatory material compiled for law enforcement purposes. This exemption's effect on...

  17. Exemption of electricity-intensive network users pursuant to paragraph 19 II 2 of the Electricity Network Charges Ordinance. Reallocation sleaze regulation and the law.; Befreiung stromintensiver Netznutzer gem. paragraph 19 II 2 StromNEV. Die Umlagenfilzregulierung und das Recht

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, Lukas [Bonn Univ. (Germany). Zentrum fuer Europaeische Integrationsforschung; Koenig, Christian [Bonn Univ. (Germany). Zentrum fuer Europaeische Integrationsforschung; Bonn Univ. (Germany). Rechts- und Staatswissenschaftliche Fakultaet

    2012-12-13

    The last major amendment of the energy economy laws in the summer of 2011 included changes to paragraph 19 II 2 of the Electricity Network Charges Ordinance. Whereas previously individual agreements on network charges had only been permissible in cases of atypical network use, the present amendment now entirely exempts electricity-intensive customers from network charges. If the loss in revenue which results from the exemption of large network users is socialised through a reallocation mechanism and is thus borne by the entirety of network users, then such a reallocation scheme will have the economic effect of a consumer tax serving the redistribution of wealth from bottom to top under the pretence of securing international competitiveness and employment, circumventing the arduous route via the national fiscal budget. There is nothing like the law, especially the law on EU subsidies, as a means of stabilising this lobby-driven regulatory roller-coaster ride.

  18. Humanoid by ROBO-BLOCK

    Science.gov (United States)

    Niimi, Hirofumi; Koike, Minoru; Takeuchi, Seiichi; Douhara, Noriyoshi

    2007-12-01

    Humanoid by ROBO-BLOCK (robot block system) and the rational formula of robots were proposed. ROBO-BLOCK is composed of servo motors, the parts for servomotor rotor, the brackets for servomotor fixation, the board parts and the controllers. A robot can be assembled easily by ROBO-BLOCK. Meanwhile, it is convenient when the structure of the robot can be described easily as a character. The whole structure of the robot is expressed as rational formula of the robot to show molecule structure in chemistry. ROBO-BLOCK can be useful for not only the research but also the education. Creative student experiment was done in the college of industrial technology.

  19. 77 FR 47287 - Bacillus thuringiensis eCry3.1Ab Protein in Corn; Exemption From the Requirement of a Tolerance

    Science.gov (United States)

    2012-08-08

    ... AGENCY 40 CFR Part 174 Bacillus thuringiensis eCry3.1Ab Protein in Corn; Exemption From the Requirement...-incorporated protectant (PIP), Bacillus thuringiensis eCry3.1Ab protein in corn, in or on the food and feed... permissible level for residues of Bacillus thuringiensis eCry3.1Ab protein in corn. DATES: This regulation...

  20. 77 FR 74544 - Eagle Fund III, L.P., License No. 07/07-0116; Notice Seeking Exemption Under Section 312 of the...

    Science.gov (United States)

    2012-12-14

    ... ADMINISTRATION Eagle Fund III, L.P., License No. 07/07-0116; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III, L.P... interest, of the Small Business Administration Rules and Regulations (13 CFR part 107). Eagle Fund III,...

  1. 77 FR 74545 - Eagle Fund III-A, L.P.; License No. 07/07-0117: Notice Seeking Exemption Under Section 312 of the...

    Science.gov (United States)

    2012-12-14

    ... ADMINISTRATION Eagle Fund III-A, L.P.; License No. 07/07-0117: Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III-A, L.P... interest, of the Small Business Administration Rules and Regulations (13 CFR part 107). Eagle Fund III-...

  2. Spintronics: Conceptual Building Blocks

    Science.gov (United States)

    Ansermet, J.-Ph.

    The purpose of this introduction to spintronics is to provide some elementary description of its conceptual building blocks. Thus, it is intended for a newcomer to the field. After recalling rudimentary descriptions of spin precession and spin relaxation, spin-dependent transport is treated within the Boltzmann formalism. This suffices to introduce key notions such as the spin asymmetry of the conductivities in the two-current model, the spin diffusion length, and spin accumulation. Two basic mechanisms of spin relaxation are then presented, one arising from spin-orbit scattering and the other from electron-magnon collisions. Finally, the action of a spin-polarized current on magnetization is presented in a thermodynamics framework. This introduces the notion of spin torque and the characteristic length scale over which the transverse spin polarization of conduction electron decays as it is injected into a magnet.

  3. Photovoltaic building blocks

    DEFF Research Database (Denmark)

    Hanberg, Peter Jesper; Jørgensen, Anders Michael

    2014-01-01

    it directcompetitive with fossil energy sources a further reduction is needed. By increasing the efficiency of the solar cells one gain an advantage through the whole chain of cost. So that per produced Watt of power less material is spent, installation costs are lower, less area is used etc. With an average...... efficiency of about 15% for commercial Silicon solar cells there is still much to gain. DTU Danchip provides research facilities, equipment and expertise for the building blocks that comprises fabricating the efficient solar cell. In order to get more of the sun light into the device we provide thin film......Photovoltaics (PV), better known as solar cells, are now a common day sight on many rooftops in Denmark.The installed capacity of PV systems worldwide is growing exponentially1 and is the third most importantrenewable energy source today. The cost of PV is decreasing fast with ~10%/year but to make...

  4. Celiac ganglia block

    Energy Technology Data Exchange (ETDEWEB)

    Akinci, Devrim [Department of Radiology, Hacettepe University School of Medicine, Sihhiye, 06100 Ankara (Turkey); Akhan, Okan [Department of Radiology, Hacettepe University School of Medicine, Sihhiye, 06100 Ankara (Turkey)]. E-mail: oakhan@hacettepe.edu.tr

    2005-09-01

    Pain occurs frequently in patients with advanced cancers. Tumors originating from upper abdominal viscera such as pancreas, stomach, duodenum, proximal small bowel, liver and biliary tract and from compressing enlarged lymph nodes can cause severe abdominal pain, which do not respond satisfactorily to medical treatment or radiotherapy. Percutaneous celiac ganglia block (CGB) can be performed with high success and low complication rates under imaging guidance to obtain pain relief in patients with upper abdominal malignancies. A significant relationship between pain relief and degree of tumoral celiac ganglia invasion according to CT features was described in the literature. Performing the procedure in the early grades of celiac ganglia invasion on CT can increase the effectiveness of the CGB, which is contrary to World Health Organization criteria stating that CGB must be performed in patients with advanced stage cancer. CGB may also be effectively performed in patients with chronic pancreatitis for pain palliation.

  5. Atomic Basic Blocks

    Science.gov (United States)

    Scheler, Fabian; Mitzlaff, Martin; Schröder-Preikschat, Wolfgang

    Die Entscheidung, einen zeit- bzw. ereignisgesteuerten Ansatz für ein Echtzeitsystem zu verwenden, ist schwierig und sehr weitreichend. Weitreichend vor allem deshalb, weil diese beiden Ansätze mit äußerst unterschiedlichen Kontrollflussabstraktionen verknüpft sind, die eine spätere Migration zum anderen Paradigma sehr schwer oder gar unmöglich machen. Wir schlagen daher die Verwendung einer Zwischendarstellung vor, die unabhängig von der jeweils verwendeten Kontrollflussabstraktion ist. Für diesen Zweck verwenden wir auf Basisblöcken basierende Atomic Basic Blocks (ABB) und bauen darauf ein Werkzeug, den Real-Time Systems Compiler (RTSC) auf, der die Migration zwischen zeit- und ereignisgesteuerten Systemen unterstützt.

  6. 40 CFR 180.1160 - Jojoba oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Jojoba oil; exemption from the... Exemptions From Tolerances § 180.1160 Jojoba oil; exemption from the requirement of a tolerance. The insecticide and spray tank adjuvant jojoba oil is exempted from the requirement of a tolerance in or on...

  7. 40 CFR 180.1049 - Carbon dioxide; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Carbon dioxide; exemption from the... Exemptions From Tolerances § 180.1049 Carbon dioxide; exemption from the requirement of a tolerance. The insecticide carbon dioxide is exempted from the requirement of a tolerance when used after harvest in...

  8. 40 CFR 180.1291 - Cold pressed neem oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Cold pressed neem oil; exemption from... FOOD Exemptions From Tolerances § 180.1291 Cold pressed neem oil; exemption from the requirement of a tolerance. Residues of the biochemical pesticide cold pressed neem oil are exempt from the requirement of...

  9. 40 CFR 180.1269 - Bacillus mycoides Isolate J: exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus mycoides Isolate J: exemption... FOOD Exemptions From Tolerances § 180.1269 Bacillus mycoides Isolate J: exemption from the requirement of a tolerance. Bacillus mycoides isolate J is temporarily exempt from the requirement of a...

  10. 40 CFR 180.1111 - Bacillus subtilis GB03; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus subtilis GB03; exemption from... FOOD Exemptions From Tolerances § 180.1111 Bacillus subtilis GB03; exemption from the requirement of a tolerance. The biofungicide Bacillus subtilis GB03 is exempted from the requirement of a tolerance in or...

  11. 40 CFR 180.1224 - Bacillus pumilus GB34; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus pumilus GB34; exemption from... FOOD Exemptions From Tolerances § 180.1224 Bacillus pumilus GB34; exemption from the requirement of a... pesticide Bacillus pumilus GB34 when used as a seed treatment in or on all food commodities. An exemption...

  12. 40 CFR 180.1187 - L-glutamic acid; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false L-glutamic acid; exemption from the... Exemptions From Tolerances § 180.1187 L-glutamic acid; exemption from the requirement of a tolerance. L-glutamic acid is exempt from the requirement of a tolerance on all food commodities when used in...

  13. 40 CFR 180.1197 - Hydrogen peroxide; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Hydrogen peroxide; exemption from the... Exemptions From Tolerances § 180.1197 Hydrogen peroxide; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of hydrogen peroxide in or on...

  14. 40 CFR 180.1090 - Lactic acid; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Lactic acid; exemption from the... Exemptions From Tolerances § 180.1090 Lactic acid; exemption from the requirement of a tolerance. Lactic acid (2-hydroxypropanoic acid) is exempted from the requirement of a tolerance when used as a plant...

  15. 40 CFR 180.1277 - Dibasic esters; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Dibasic esters; exemption from the... Exemptions From Tolerances § 180.1277 Dibasic esters; exemption from the requirement of a tolerance. Dibasic esters (CAS Reg. No. 95481-62-2) is exempted from the requirement of a tolerance for residues when...

  16. 40 CFR 180.1262 - Sorbitol octanoate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sorbitol octanoate; exemption from the... Exemptions From Tolerances § 180.1262 Sorbitol octanoate; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of sorbitol octanoate in or on...

  17. 40 CFR 180.1232 - Lime-sulfur; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Lime-sulfur; exemption from the... Exemptions From Tolerances § 180.1232 Lime-sulfur; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of lime-sulfur....

  18. 40 CFR 180.1092 - Menthol; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Menthol; exemption from the... Exemptions From Tolerances § 180.1092 Menthol; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of the pesticidal chemical menthol...

  19. 40 CFR 180.1273 - Beauveria bassiana HF23; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Beauveria bassiana HF23; exemption... FOOD Exemptions From Tolerances § 180.1273 Beauveria bassiana HF23; exemption from the requirement of a tolerance. Residues of Beauveria bassiana HF23 are exempt from the requirement of a tolerance on all...

  20. 40 CFR 180.1145 - Pseudomonas syringae; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pseudomonas syringae; exemption from... FOOD Exemptions From Tolerances § 180.1145 Pseudomonas syringae; exemption from the requirement of a tolerance. Pseudomonas syringae is exempted from the requirement of a tolerance on all raw...

  1. 19 CFR 148.53 - Exemption for tools of trade.

    Science.gov (United States)

    2010-04-01

    ... tools of trade. (a) Exemption. Professional books, implements, instruments, or tools of trade... 19 Customs Duties 2 2010-04-01 2010-04-01 false Exemption for tools of trade. 148.53 Section 148.53 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT...

  2. 10 CFR 490.204 - Process for granting exemptions.

    Science.gov (United States)

    2010-01-01

    ... Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Mandatory State Fleet Program § 490.204 Process for granting exemptions. (a) To obtain an exemption, in whole or in part...) Alternative fuels that meet the normal requirements and practices of the principal business of the State...

  3. 12 CFR 26.5 - Small market share exemption.

    Science.gov (United States)

    2010-01-01

    ... Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MANAGEMENT OFFICIAL INTERLOCKS § 26.5 Small market share exemption. (a) Exemption. A management interlock that is prohibited by § 26.3... recent annual Summary of Deposits published by the FDIC for the RMSA or community. (b) Confirmation...

  4. 32 CFR 322.7 - Exempt systems of records.

    Science.gov (United States)

    2010-07-01

    ...) System name: Military Reserve Personnel Data Base. (2) Exemption: (i) Investigatory material compiled..., military service, federal contracts, or access to classified information may be exempt pursuant to 5 U.S.C... qualifications for federal civilian employment, military service, federal contracts, or access to...

  5. 7 CFR 1170.9 - Price reporting exemptions.

    Science.gov (United States)

    2010-01-01

    ... Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PRODUCT MANDATORY REPORTING § 1170.9 Price... markets less than 1 million pounds of dry whey per calendar year is exempt from reporting dry whey sales... pounds of nonfat dry milk per calendar year is exempt from reporting nonfat dry milk sales as...

  6. 76 FR 1197 - Detroit Edison Company, FERMI 2; Exemption

    Science.gov (United States)

    2011-01-07

    ... COMMISSION Detroit Edison Company, FERMI 2; Exemption 1.0 Background Detroit Edison Company (DECo) (the licensee) is the holder of Facility Operating License No. NFP-43 which authorizes operation of the Fermi 2... exemption stated that a tornado swept across the Fermi 2 property on June 6, 2010, and that the...

  7. 76 FR 32238 - Detroit Edison Company, Fermi 2; Exemption

    Science.gov (United States)

    2011-06-03

    ... unanticipated delays in construction schedule. 3.0 Discussion of Part 73 Schedule Exemptions From the March 31... approach set forth by the Commission and discussed in the June 4, 2009, letter. Fermi 2 Schedule Exemption... dates indicating when (1) Construction began or will begin on various phases of the project (i.e.,...

  8. 78 FR 68137 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-11-13

    ... W. O'Neill (WA) Robert M. Pickett II (MI) John N. Poland (IL) Eligio M. Ramirez (TX) Garry L. Rogers... vision requirement if the exemptions granted will not compromise safety. The Agency has concluded that granting these exemption renewals will provide a level of safety that is equivalent to or greater than...

  9. 40 CFR 266.109 - Low risk waste exemption.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.109 Low risk waste exemption. (a) Waiver of DRE standard. The DRE standard of § 266.104(a) does not apply if the boiler or... boiler or industrial furnace that is exempt under this section must conduct dispersion modeling...

  10. 27 CFR 70.241 - Property exempt from levy.

    Science.gov (United States)

    2010-04-01

    .... There shall be exempt from levy: (1) Wearing apparel and school books. Such items of wearing apparel and such school books as are necessary for the taxpayer or for members of the taxpayer's family. Expensive... members of the taxpayer's family, are not exempt from levy. (2) Fuel, provisions, furniture, and...

  11. 28 CFR 16.76 - Exemption of Justice Management Division.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Justice Management Division. 16.76 Section 16.76 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF... Management Division. (a) The following system of records is exempt from 5 U.S.C. 552a(d): (1)...

  12. 41 CFR 51-9.102-1 - Specific exemptions.

    Science.gov (United States)

    2010-07-01

    ...-General Policy § 51-9.102-1 Specific exemptions. Systems of records maintained by the Committee which have... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Specific exemptions. 51-9.102-1 Section 51-9.102-1 Public Contracts and Property Management Other Provisions Relating to...

  13. 28 CFR 505.3 - Inmates exempted from fee assessment.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Inmates exempted from fee assessment. 505.3 Section 505.3 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE GENERAL MANAGEMENT AND ADMINISTRATION COST OF INCARCERATION FEE § 505.3 Inmates exempted from fee assessment. Inmates...

  14. 10 CFR 871.1 - National security exemption.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false National security exemption. 871.1 Section 871.1 Energy DEPARTMENT OF ENERGY AIR TRANSPORTATION OF PLUTONIUM § 871.1 National security exemption. (a) The following... order to preserve the chemical, physical, or isotopic properties of the item. The Deputy...

  15. 76 FR 37171 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-06-24

    ... severe hypoglycemic reactions resulting in loss of consciousness or seizure, requiring the assistance of... annual checklist with a comprehensive medical evaluation; (2) that each individual reports within 2.... Conclusion Based upon its evaluation of the twenty-four exemption applications, FMCSA exempts, Alfonso...

  16. 75 FR 38864 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-06

    ... 16, 2010 (75 FR 27621). Discussion of Comments FMCSA received no comments in this proceeding...-11714; FMCSA- 2008-0021] Qualification of Drivers; Exemption Renewals; Vision AGENCY: Federal Motor... announced its decision to renew the exemptions from the vision requirement in the Federal Motor...

  17. 76 FR 37883 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-06-28

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... receipt of exemption applications from certain individuals, and requested comments from the public (76 FR... discussed in detail in the May 5, 2011 notice (76 FR 25764). Basis for Exemption Determination Under 49...

  18. 77 FR 75494 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-12-20

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... receipt of exemption applications from certain individuals, and requested comments from the public (77 FR... discussed in detail in the October 23, 2012 notice (77 FR 64839). Basis for Exemption Determination Under...

  19. 77 FR 22059 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-04-12

    ... the FDMS published in the Federal Register on January 17, 2008 (73 FR 3316), or you may visit http... receipt of exemption applications from certain individuals, and requested comments from the public (77 FR... February 13, 2012 notice (77 FR 7657). Basis for Exemption Determination Under 49 U.S.C. 31136(e) and...

  20. 21 CFR 801.110 - Retail exemption for prescription devices.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Retail exemption for prescription devices. 801.110 Section 801.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From Adequate Directions for Use § 801.110 Retail...

  1. 29 CFR 779.385 - May qualify as exempt establishments.

    Science.gov (United States)

    2010-07-01

    ... in clause (B) of the exemption. Typical examples of such are the concessionaires at amusement parks... Establishments Seasonal Amusement Or Recreational Establishments § 779.385 May qualify as exempt establishments. An amusement or recreational establishment operating on a seasonal basis may qualify as an...

  2. 26 CFR 1.1502-100 - Corporations exempt from tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 12 2010-04-01 2010-04-01 false Corporations exempt from tax. 1.1502-100...) INCOME TAX (CONTINUED) INCOME TAXES Administrative Provisions and Other Rules § 1.1502-100 Corporations... return year of a group of two or more corporations described in section 1504(e) which are exempt...

  3. 19 CFR 12.104h - Exempt materials and articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Exempt materials and articles. 12.104h Section 12... THE TREASURY SPECIAL CLASSES OF MERCHANDISE Cultural Property § 12.104h Exempt materials and articles... material or any article of cultural property which is imported into the U.S. for temporary exhibition...

  4. 19 CFR 148.46 - Sale of exempted articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Sale of exempted articles. 148.46 Section 148.46... exempted articles. (a) Sale resulting in forfeiture. The following articles or their value (to be recovered... paragraph (b) of this section is followed: (1) Any jewelry or similar articles of personal adornment...

  5. Large Block Test Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lin, W

    2001-12-01

    This report documents the Large-Block Test (LBT) conducted at Fran Ridge near Yucca Mountain, Nevada. The LBT was a thermal test conducted on an exposed block of middle non-lithophysal Topopah Spring tuff (Tptpmn) and was designed to assist in understanding the thermal-hydrological-mechanical-chemical (THMC) processes associated with heating and then cooling a partially saturated fractured rock mass. The LBT was unique in that it was a large (3 x 3 x 4.5 m) block with top and sides exposed. Because the block was exposed at the surface, boundary conditions on five of the six sides of the block were relatively well known and controlled, making this test both easier to model and easier to monitor. This report presents a detailed description of the test as well as analyses of the data and conclusions drawn from the test. The rock block that was tested during the LBT was exposed by excavation and removal of the surrounding rock. The block was characterized and instrumented, and the sides were sealed and insulated to inhibit moisture and heat loss. Temperature on the top of the block was also controlled. The block was heated for 13 months, during which time temperature, moisture distribution, and deformation were monitored. After the test was completed and the block cooled down, a series of boreholes were drilled, and one of the heater holes was over-cored to collect samples for post-test characterization of mineralogy and mechanical properties. Section 2 provides background on the test. Section 3 lists the test objectives and describes the block site, the site configuration, and measurements made during the test. Section 3 also presents a chronology of events associated with the LBT, characterization of the block, and the pre-heat analyses of the test. Section 4 describes the fracture network contained in the block. Section 5 describes the heating/cooling system used to control the temperature in the block and presents the thermal history of the block during the test

  6. 49 CFR 801.58 - Records for regulation of financial institutions.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Records for regulation of financial institutions... for regulation of financial institutions. Pursuant to 5 U.S.C. 552(b)(8), records compiled for agencies regulating or supervising financial institutions are exempt from public disclosure....

  7. Federal Environmental Regulations Impacting Hydrocarbon Exploration, Drilling, and Production Operations

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, Herbert B.; Johnson, William I.

    1999-04-27

    Waste handling and disposal from hydrocarbon exploration, drilling, and production are regulated by the US Environmental Protection Agency (EPA) through federal and state regulations and/or through implementation of federal regulations. Some wastes generated in these operations are exempt under the Resource Conservation and Recovery Act (RCRA) but are not exempt under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), Superfund Amendments and Reauthorization Act (SARA), and other federal environmental laws. Exempt wastes remain exempt only if they are not mixed with hazardous wastes or hazardous substances. Once mixture occurs, the waste must be disposed as a hazardous material in an approved hazardous waste disposal facility. Before the Clean Air Act as amended in 1990, air emissions from production, storage, steam generation, and compression facilities associated with hydrocarbon exploration, drilling, and production industry were not regulated. A critical proposed regulatory change which will significantly effect Class II injection wells for disposal of produced brine and injection for enhanced oil recovery is imminent. Federal regulations affecting hydrocarbon exploration, drilling and production, proposed EPA regulatory changes, and a recent significant US Court of Appeals decision are covered in this report. It appears that this industry will, in the future, fall under more stringent environmental regulations leading to increased costs for operators.

  8. 78 FR 20032 - Styrene-Ethylene-Propylene Block Copolymer; Tolerance Exemption

    Science.gov (United States)

    2013-04-03

    ... integral part of its composition, the atomic elements carbon, hydrogen, and oxygen. 3. The polymer does not contain as an integral part of its composition, except as impurities, any element other than those listed..., Pesticides and pests, Reporting and recordkeeping requirements. Dated: March 26, 2013. Lois Rossi,...

  9. Dimensional Reduction for Conformal Blocks

    CERN Document Server

    Hogervorst, Matthijs

    2016-01-01

    We consider the dimensional reduction of a CFT, breaking multiplets of the d-dimensional conformal group SO(d+1,1) up into multiplets of SO(d,1). This leads to an expansion of d-dimensional conformal blocks in terms of blocks in d-1 dimensions. In particular, we obtain a formula for 3d conformal blocks as an infinite sum over 2F1 hypergeometric functions with closed-form coefficients.

  10. Ambulatory surgery center joint ventures involving tax-exempt entities.

    Science.gov (United States)

    Becker, S; Pristave, R J; McConnell, W

    1999-01-01

    This article provides an overview of the tax-exempt related issues for ambulatory surgery center joint ventures involving tax-exempt entities. The article analyzes the key points of analysis of the guidance released by the IRS, in particular General Counsel Memorandum 39862, Revenue Ruling 98-15, and Redlands Surgical Services v. Commissioner of the Internal Revenue Service. These key points include whether the venture results in private inurement to insiders and whether the venture furthers the charitable purposes of the tax-exempt entity. The article also provides practical guidance to analyze the documents and structure of the joint venture to ensure compliance with the IRS guidance. These practical considerations include, among other things, whether the charitable purposes of the tax-exempt entity are clearly expressed in the documents and whether the tax-exempt entity has sufficient control over the joint venture to ensure the charitable purposes are being adhered to.

  11. Common blocks for ASQS(12

    Directory of Open Access Journals (Sweden)

    Lorenzo Milazzo

    1997-05-01

    Full Text Available An ASQS(v is a particular Steiner system featuring a set of v vertices and two separate families of blocks, B and G, whose elements have a respective cardinality of 4 and 6. It has the property that any three vertices of X belong either to a B-block or to a G-block. The parameter cb is the number of common blocks in two separate ASQSs, both defined on the same set of vertices X . In this paper it is shown that cb ≤ 29 for any pair of ASQSs(12.

  12. Eikonalization of Conformal Blocks

    CERN Document Server

    Fitzpatrick, A Liam; Walters, Matthew T; Wang, Junpu

    2015-01-01

    Classical field configurations such as the Coulomb potential and Schwarzschild solution are built from the $t$-channel exchange of many light degrees of freedom. We study the CFT analog of this phenomenon, which we term the `eikonalization' of conformal blocks. We show that when an operator $T$ appears in the OPE $\\mathcal{O}(x) \\mathcal{O}(0)$, then the large spin $\\ell$ Fock space states $[TT \\cdots T]_{\\ell}$ also appear in this OPE with a computable coefficient. The sum over the exchange of these Fock space states in an $\\langle \\mathcal{O} \\mathcal{O} \\mathcal{O} \\mathcal{O} \\rangle$ correlator build the classical `$T$ field' in the dual AdS description. In some limits the sum of all Fock space exchanges can be represented as the exponential of a single $T$ exchange in the 4-pt correlator of $\\mathcal{O}$. Our results should be useful for systematizing $1/\\ell$ perturbation theory in general CFTs and simplifying the computation of large spin OPE coefficients. As examples we obtain the leading $\\log \\ell$...

  13. Adductor Canal Block versus Femoral Nerve Block and Quadriceps Strength

    DEFF Research Database (Denmark)

    Jæger, Pia Therese; Nielsen, Zbigniew Jerzy Koscielniak; Henningsen, Lene Marianne;

    2013-01-01

    : The authors hypothesized that the adductor canal block (ACB), a predominant sensory blockade, reduces quadriceps strength compared with placebo (primary endpoint, area under the curve, 0.5-6 h), but less than the femoral nerve block (FNB; secondary endpoint). Other secondary endpoints were...

  14. 75 FR 4295 - Premanufacture Notification Exemption for Polymers; Amendment of Polymer Exemption Rule to...

    Science.gov (United States)

    2010-01-27

    ... are required to show photographic identification, pass through a metal detector, and sign the EPA... proposed rule. Comments were submitted by the Society of the Plastics Industry, E.I. DuPont de Nemours and... be subject to the user fee. The Agency has never received a photographic film exemption request...

  15. 29 CFR 779.347 - Exemption limited to “recognized retail establishment”; factories not exempt.

    Science.gov (United States)

    2010-07-01

    ... under the exemption are custom tailor shops, candy shops, ice cream parlors, bakeries, drug stores, optometrist establishments, retail ice plants and other local retail establishments which make or process the... Retail or Service Establishments Engaging in Manufacturing and Processing Activities; Section...

  16. Block Transfer Agreement Evaluation Project

    Science.gov (United States)

    Bastedo, Helena

    2010-01-01

    The objective of this project is to evaluate for the British Columbia Council on Admissions and Transfer (BCCAT) the effectiveness of block transfer agreements (BTAs) in the BC Transfer System and recommend steps to be taken to improve their effectiveness. Findings of this study revealed that institutions want to expand block credit transfer;…

  17. Four-block beam collimator

    CERN Multimedia

    1977-01-01

    The photo shows a four-block collimator installed on a control table for positioning the alignment reference marks. Designed for use with the secondary beams, the collimators operated in vacuum conditions. The blocks were made of steel and had a standard length of 1 m. The maximum aperture had a square coss-section of 144 cm2. (See Annual Report 1976.)

  18. OPAL Various Lead Glass Blocks

    CERN Multimedia

    These lead glass blocks were part of a CERN detector called OPAL (one of the four experiments at the LEP particle detector). OPAL uses some 12 000 blocks of glass like this to measure particle energies in the electromagnetic calorimeter. This detector measured the energy deposited when electrons and photons were slowed down and stopped.

  19. Block storage subsystem performance analysis

    CERN Document Server

    CERN. Geneva

    2016-01-01

    You feel that your service is slow because of the storage subsystem? But there are too many abstraction layers between your software and the raw block device for you to debug all this pile... Let's dive on the platters and check out how the block storage sees your I/Os! We can even figure out what those patterns are meaning.

  20. AtMyb7, a subgroup 4 R2R3 Myb, negatively regulates ABA-induced inhibition of seed germination by blocking the expression of the bZIP transcription factor ABI5

    KAUST Repository

    Kim, Junhyeok

    2014-08-27

    Various Myb proteins have been shown to play crucial roles in plants, including primary and secondary metabolism, determination of cell fate and identity, regulation of development and involvement in responses to biotic and abiotic stresses. The 126 R2R3 Myb proteins (with two Myb repeats) have been found in Arabidopsis; however, the functions of most of these proteins remain to be fully elucidated. In the present study, we characterized the function of AtMyb7 using molecular biological and genetic analyses. We used qRT-PCR to determine the levels of stress-response gene transcripts in wild-type and atmyb7 plants. We showed that ArabidopsisAtMyb7 plays a critical role in seed germination. Under abscisic acid (ABA) and high-salt stress conditions, atmyb7 plants showed a lower germination rate than did wild-type plants. Furthermore, AtMyb7 promoter:GUS seeds exhibited different expression patterns in response to variations in the seed imbibition period. AtMyb7 negatively controls the expression of the gene encoding bZIP transcription factor, ABI5, which is a key transcription factor in ABA signalling and serves as a crucial regulator of germination inhibition in Arabidopsis. © 2014 John Wiley & Sons Ltd.

  1. Conformal Nets II: Conformal Blocks

    Science.gov (United States)

    Bartels, Arthur; Douglas, Christopher L.; Henriques, André

    2017-03-01

    Conformal nets provide a mathematical formalism for conformal field theory. Associated to a conformal net with finite index, we give a construction of the `bundle of conformal blocks', a representation of the mapping class groupoid of closed topological surfaces into the category of finite-dimensional projective Hilbert spaces. We also construct infinite-dimensional spaces of conformal blocks for topological surfaces with smooth boundary. We prove that the conformal blocks satisfy a factorization formula for gluing surfaces along circles, and an analogous formula for gluing surfaces along intervals. We use this interval factorization property to give a new proof of the modularity of the category of representations of a conformal net.

  2. Free-riding, fairness and the rights of minority groups in exemption from mandatory childhood vaccination.

    Science.gov (United States)

    May, Thomas; Silverman, Ross D

    2005-01-01

    The authority of government to require participation in mandatory childhood vaccination programs may not target specific groups for either participation or exemption on a discriminatory basis. This poses difficulties when allowing religious or philosophical exemptions to mandatory vaccination, because certain groups are more likely to appeal for exemption. Avoiding loss of herd immunity, then, may require either discrimination against these groups by disallowing an exemption option that is available to others, or by denying the good of an exemption option to the entire population because of the action of certain groups. To avoid this unacceptable choice, steps must be taken now to more stringently enforce exemption requirements.

  3. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    Science.gov (United States)

    2010-10-18

    ... Federal Register, 73 FR 25594, May 7, 2008. The proposed amendments: (1) Waived all copying fees in..., 73 FR 54595, September 22, 2008, certain portions of BGFRS-37 (Electronic Applications) may be exempt... CFR Part 261a Privacy Act of 1974; Privacy Act Regulation AGENCY: Board of Governors of the...

  4. Interaction between OHS regulation and OHS certification in Denmark

    DEFF Research Database (Denmark)

    Hendriksen, Kåre; Jørgensen, Kirsten; Jørgensen, Ulrik

    2010-01-01

    In 2001, the Danish Parliament approved a law on OHS certification that provided economic support to enterprises/organizations that were certified according to one of the two national OHS standards. These certified enterprises/organizations were also exempt from the initial inspection by the Dani...... recommendations for optimizing the interaction between OHS certification and regulation/control ....

  5. 77 FR 69736 - Truth in Lending (Regulation Z)

    Science.gov (United States)

    2012-11-21

    ... CFR Part 226 RIN 7100-AD94 BUREAU OF CONSUMER FINANCIAL PROTECTION 12 CFR Part 1026 Truth in Lending... the agencies' regulations that implement the Truth in Lending Act (TILA). Effective July 21, 2011, the... threshold in the Truth in Lending Act (TILA) for exempt consumer credit transactions \\1\\ from $25,000 to...

  6. MarineMineralsProgramBlocks

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains OCS block outlines and delineated polygons in ESRI ArcGIS shape file format for the BOEM Gulf of Mexico Region that contain sediment resources...

  7. Hawaii Census 2000 Block Groups

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer represents Census 2000 demographic data derived from the PL94-171 redistricting files and SF3. Census geographic entities include blocks, blockgroups...

  8. Left bundle-branch block

    DEFF Research Database (Denmark)

    Risum, Niels; Strauss, David; Sogaard, Peter;

    2013-01-01

    The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a fundamental understanding of physiology have recently...

  9. Multi-block and path modelling procedures

    DEFF Research Database (Denmark)

    Høskuldsson, Agnar

    2008-01-01

    The author has developed a unified theory of path and multi-block modelling of data. The data blocks are arranged in a directional path. Each data block can lead to one or more data blocks. It is assumed that there is given a collection of input data blocks. Each of them is supposed to describe one...

  10. NANOSTRUCTURES OF FUNCTIONAL BLOCK COPOLYMERS

    Institute of Scientific and Technical Information of China (English)

    Guojun Liu

    2000-01-01

    Nanostructure fabrication from block copolymers in my group normally involves polymer design, synthesis, selfassembly, selective domain crosslinking, and sometimes selective domain removal. Preparation of thin films with nanochannels was used to illustrate the strategy we took. In this particular case, a linear triblock copolymer polyisopreneblock-poly(2-cinnamoylethyl methacrylate)-block-poly(t-butyl acrylate), PI-b-PCEMA-b-PtBA, was used. Films, 25 to50μm thick, were prepared from casting on glass slides a toluene solution of PI-b-PCEMA-b-PtBA and PtBA homopolymer,hPtBA, where hPtBA is shorter than the PtBA block. At the hPtBA mass fraction of 20% relative to the triblock or the total PtBA (hPtBA and PtBA block) volume fraction of 0.44, hPtBA and PtBA formed a seemingly continuous phase in the matrix of PCEMA and PI. Such a block segregation pattern was locked in by photocrosslinking the PCEMA domain. Nanochannels were formed by extracting out hPtBA with solvent. Alternatively, larger channels were obtained from extracting out hPtBA and hydrolyzing the t-butyl groups of the PtBA block. Such membranes were not liquid permeable but had gas permeability constants ~6 orders of magnitude higher than that of low-density polyethylene films.

  11. 76 FR 37173 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-06-24

    ... self- addressed, stamped envelope or postcard or print the acknowledgement page that appears after... immediate steps to revoke the exemption of a driver. Issued on: June 13, 2011. Larry W. Minor,...

  12. 77 FR 64582 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-10-22

    ..., please include a self- addressed, stamped envelope or postcard or print the acknowledgement page that... immediate steps to revoke the exemption of a driver. Issued on: October 9, 2012. Larry W. Minor,...

  13. 76 FR 37168 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-06-24

    ... self- addressed, stamped envelope or postcard or print the acknowledgement page that appears after... immediate steps to revoke the exemption of a driver. Issued on: June 13, 2011. Larry W. Minor,...

  14. 75 FR 32983 - Commercial Driver's License (CDL) Standards: Exemption

    Science.gov (United States)

    2010-06-10

    ... fertilizers and limited quantities of diesel fuel or liquid fertilizer. NAAA wants FMCSA, by exemption, to...). NAAA NAAA is a trade association representing those engaged in the commercial application of...

  15. 75 FR 1449 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-01-11

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... . Background On October 29, 2009, FMCSA published a notice of receipt of Federal diabetes...

  16. 75 FR 27622 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-05-17

    ... decided to extend each exemption for a renewable two-year period. They are: Paul D. Crouch, John M. Doney.... Lopez, Earl E. Martin, Bobby L. Mashburn, Brian E. Monaghan, William P. Murphy, Roy J. Oltman, Albert...

  17. 7 CFR 504.4 - Exemptions from user fee charges.

    Science.gov (United States)

    2010-01-01

    ... cooperators designated by the Curator of the ARS Patent Culture Collection are exempt from fee assessments. (b) The Curator of the ARS Patent Culture Collection is delegated the authority to approve and...

  18. 21 CFR 1310.12 - Exempt chemical mixtures.

    Science.gov (United States)

    2010-04-01

    ... § 1310.13 affects the criminal liability for illegal possession, distribution, exportation, or importation of listed chemicals contained in the exempt chemical mixture or the civil liability for...

  19. 21 CFR 1316.24 - Exemption from prosecution for researchers.

    Science.gov (United States)

    2010-04-01

    ... of the Drug Enforcement Administration, on his own motion or upon request in writing from the... afforded by the grant of exemption from prosecution during the research period shall be perpetual....

  20. 77 FR 59447 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ... [Docket No. FMCSA-2012-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY... from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted,...

  1. 77 FR 3549 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-24

    ... [Docket No. FMCSA-2011-0368] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY... from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted,...

  2. 75 FR 69734 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-11-15

    ... [Docket No. FMCSA-2010-0355] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY... from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted,...

  3. 78 FR 78479 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-26

    ... prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  4. 75 FR 80889 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-12-23

    ...; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate...

  5. 76 FR 55460 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-09-07

    ...; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate...

  6. 77 FR 64181 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-18

    ...; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA... with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in...

  7. 76 FR 17475 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-03-29

    ... for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... for individual assessment of drivers with diabetes mellitus, and be consistent with the...

  8. 77 FR 18302 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-27

    ... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... for individual assessment of drivers with diabetes mellitus, and be consistent with the...

  9. 77 FR 33551 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-06

    ... prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications;...

  10. 76 FR 39976 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-07-07

    .... Petition for Exemption Docket No.: FAA-2011-0457. Petitioner: Gama Charters, Inc. Section of 14 CFR Affected: 14 CFR 135.151(h). Description of Relief Sought: Gama Charters, Inc. requests relief to...

  11. 29 CFR 541.203 - Administrative exemption examples.

    Science.gov (United States)

    2010-07-01

    ... real estate transaction or a collective bargaining agreement, or designing and implementing productivity improvements) generally meets the duties requirements for the administrative exemption, even if... or safety, building or construction, health or sanitation, environmental or soils specialists...

  12. 49 CFR 1039.11 - Miscellaneous commodities exemptions.

    Science.gov (United States)

    2010-10-01

    .... 40251 ......do. Chemical or petroleum waste, including spent. 40261 ......do. Rubber or plastic scrap or... market dominance has been made. However, this exemption shall not be construed as affecting in any...

  13. 78 FR 12813 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-02-25

    .... O'Dell, Jr. (OK). Kenneth L. Bowers, Jr. (MN)..... Jerry W. Parker (OH). Eddie A. Branham (NC) Gary...). Harry J. McSuley, Jr. (PA)...... The exemptions are extended subject to the following conditions:...

  14. 77 FR 23800 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-04-20

    ...) Michael D. Kilgore (TX) Joseph J. Kushak (MI) Douglas L. Norman (NC) Richard W. Pierce (NM) Christopher A. Reineck (OH) Caroll R. Rogers (CA) Wayne J. Savage (VA) Anthony T. Smith (MI) The exemptions are...

  15. MORINGA TEA BLOCKS ACUTE LUNG INFLAMMATION INDUCED BY SWINE CONFINEMENT DUST THROUGH A MECHANISM INVOLVING TNF-α EXPRESSION, C-JUN N-TERMINAL KINASE ACTIVATION AND NEUTROPHIL REGULATION

    Directory of Open Access Journals (Sweden)

    Mykea Mcknight

    2014-01-01

    Full Text Available Plant based products represent a promising alternative to conventional treatments for inflammation. Moringa oleifera Lam is a tree rich in proteins, vitamins, minerals and a variety of phytochemcals with health benefits. Among the reported health benefits are antioxidant and anti-inflammatory properties. The purpose of this study was to investigate whether tea brewed from dried Moringa leaves would abrogate inflammation in a mouse model of acute lung inflammation induced by LPS or extracts prepared from dust collected from a swine confinement facility (DE. Mice were offered water or Moringa tea for seven days. Tea consumption was significantly greater than that of water consumption on days 1 and 6, but there were no significant differences in weight gain or food consumption. On day seven, mice from both groups were forced to inhale, via intranasal challenge, either Phosphate Buffered Saline (PBS, Lipopolysaccharide (LPS [10 µg mL-1] or DE [10%]. Compared to mice that drank water, mice that drank Moringa tea had significantly less protein (p<0.05 and cellular influx (p<0.0001 into the lung after inhalation of 10% DE. No difference in neutrophil migration into the lungs of water and M. tea groups after LPS or DE challenge was detected. But mice that drank tea had significantly (p<0.05 more neutrophils with apoptotic morphology after DE challenge. TNF-α expression 24 h after inhalation of 10% DE, was significantly higher (p<0.05 in lungs of M. tea mouse group as compared to water group. This increase in TNF-α was accompanied by higher levels of pro and anti-inflammatory cytokines. Finally, activation of c-Jun N-terminal Kinase (JNK in lungs of M. tea+DE group 24 h post inhalation was decreased. Taken together these results suggest that Moringa oleifera leaf tea exerts anti-inflammatory properties on acute lung inflammation induced by swine confinement dust through a mechanism involving neutrophil regulation and JNK

  16. Skin delivery by block copolymer nanoparticles (block copolymer micelles).

    Science.gov (United States)

    Laredj-Bourezg, Faiza; Bolzinger, Marie-Alexandrine; Pelletier, Jocelyne; Valour, Jean-Pierre; Rovère, Marie-Rose; Smatti, Batoule; Chevalier, Yves

    2015-12-30

    Block copolymer nanoparticles often referred to as "block copolymer micelles" have been assessed as carriers for skin delivery of hydrophobic drugs. Such carriers are based on organic biocompatible and biodegradable materials loaded with hydrophobic drugs: poly(lactide)-block-poly(ethylene glycol) copolymer (PLA-b-PEG) nanoparticles that have a solid hydrophobic core made of glassy poly(d,l-lactide), and poly(caprolactone)-block-poly(ethylene glycol) copolymer (PCL-b-PEG) nanoparticles having a liquid core of polycaprolactone. In vitro skin absorption of all-trans retinol showed a large accumulation of retinol in stratum corneum from both block copolymer nanoparticles, higher by a factor 20 than Polysorbate 80 surfactant micelles and by a factor 80 than oil solution. Additionally, skin absorption from PLA-b-PEG nanoparticles was higher by one order of magnitude than PCL-b-PEG, although their sizes (65nm) and external surface (water-swollen PEG layer) were identical as revealed by detailed structural characterizations. Fluorescence microscopy of histological skin sections provided a non-destructive picture of the storage of Nile Red inside stratum corneum, epidermis and dermis. Though particle cores had a different physical states (solid or liquid as measured by (1)H NMR), the ability of nanoparticles for solubilization of the drug assessed from their Hildebrand solubility parameters appeared the parameter of best relevance regarding skin absorption.

  17. Optimal Backward Perturbation Analysis for the Block Skew Circulant Linear Systems with Skew Circulant Blocks

    Directory of Open Access Journals (Sweden)

    Zhaolin Jiang

    2014-01-01

    Full Text Available We first give the block style spectral decomposition of arbitrary block skew circulant matrix with skew circulant blocks. Secondly, we obtain the singular value of block skew circulant matrix with skew circulant blocks as well. Finally, based on the block style spectral decomposition, we deal with the optimal backward perturbation analysis for the block skew circulant linear system with skew circulant blocks.

  18. 76 FR 1602 - Proposed Information Collection; Comment Request; Scientific Research, Exempted Fishing, and...

    Science.gov (United States)

    2011-01-11

    ...; Scientific Research, Exempted Fishing, and Exempted Activity Submissions AGENCY: National Oceanic and... Fishing Permits (EFPs), Scientific Research Permits (SRPs), Display Permits, Letters of Acknowledgment... necessary for the collection of Highly Migratory Species (HMS) for public display and scientific...

  19. 78 FR 3079 - Qualification of Drivers; Exemption Applications; Epilepsy and Seizure Disorders

    Science.gov (United States)

    2013-01-15

    ... physician is supportive of Mr. Spencer being granted an exemption. Brian J. Wiggins Mr. Wiggins is a 52 year.... Wiggins being granted an exemption. Timothy M. Zarahtka Mr. Zarahtka is a 37 year-old Class D driver...

  20. 76 FR 21426 - Union Pacific Railroad Company-Temporary Trackage Rights Exemption-BNSF Railway Company

    Science.gov (United States)

    2011-04-15

    ... Surface Transportation Board Union Pacific Railroad Company--Temporary Trackage Rights Exemption--BNSF Railway Company AGENCY: Surface Transportation Board, DOT. ACTION: Partial Revocation of Exemption... protective conditions set forth in Oregon Short Line Railroad--Abandonment Portion Goshen Branch...

  1. 75 FR 61694 - Notice of Request for Extension of the Organic Assessment Exemption

    Science.gov (United States)

    2010-10-06

    ... exemption from market promotion assessments under 26 marketing order programs. DATES: Comments on this... matter of public record. SUPPLEMENTARY INFORMATION: Title: Organic Handler Market Promotion Assessment... ``Certified Organic Handler Application for Exemption from Market Promotion Assessments Paid Under...

  2. 78 FR 39493 - Patient Protection and Affordable Care Act; Exchange Functions: Eligibility for Exemptions...

    Science.gov (United States)

    2013-07-01

    ...; Exchange Functions: Eligibility for Exemptions; Miscellaneous Minimum Essential Coverage Provisions; Final... health benefits coverage, such as a state health benefits risk pool, as minimum essential coverage. This...; Exchange Functions: Eligibility for Exemptions; Miscellaneous Minimum Essential Coverage Provisions''...

  3. 78 FR 14013 - Medical Devices; Exemption From Premarket Notification; Class II Devices; Wheelchair Elevator

    Science.gov (United States)

    2013-03-04

    ... Notification; Class II Devices; Wheelchair Elevator AGENCY: Food and Drug Administration, HHS. ACTION: Final... requesting exemption from premarket notification requirements for wheelchair elevator devices commonly known... another, usually in a wheelchair. This order exempts wheelchair elevators, class II devices,...

  4. Cancer Treatment Measures – PPS-Exempt Cancer Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Prospective Payment System (PPS)-Exempt Cancer Hospital Quality Reporting (PCHQR) Program currently uses three cancer specific measures. The resulting PPS-Exempt...

  5. 40 CFR 180.1041 - Nosema locustae; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... insecticide Nosema locustae is exempted from the requirement of a tolerance for residues in or on all...

  6. 40 CFR 180.1050 - Nitrogen; exemption from the requirements of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... AGENCY (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD... insecticide nitrogen is exempted from the requirements of a tolerance when used after harvest in modified atmospheres for stored product insect control on all food commodities....

  7. 75 FR 62879 - Individual Exemption Involving General Motors Company, General Motors Holdings LLC, and General...

    Science.gov (United States)

    2010-10-13

    ... Benefits Security Administration Individual Exemption Involving General Motors Company, General Motors Holdings LLC, and General Motors LLC, Located in Detroit, MI AGENCY: Employee Benefits Security... ERISA (the Notice).\\2\\ The proposed exemption was requested in an application filed by General...

  8. 78 FR 77790 - Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; General Motors...

    Science.gov (United States)

    2013-12-24

    ... National Highway Traffic Safety Administration Petition for Exemption From the Federal Motor Vehicle Theft Prevention Standard; General Motors Corporation AGENCY: National Highway Traffic Safety Administration... full General Motors Corporation's (GM) petition for an exemption of the Cadillac SRX vehicle line...

  9. 78 FR 23941 - Pilot Program for Early Feasibility Study Investigational Device Exemption Applications...

    Science.gov (United States)

    2013-04-23

    ... HUMAN SERVICES Food and Drug Administration Pilot Program for Early Feasibility Study Investigational... the Early Feasibility Study Investigational Device Exemption (IDE) Applications pilot program to May 8... ``Investigational Device Exemptions (IDE) for Early Feasibility Medical Device Clinical Studies, Including...

  10. OCM Measures – PPS-Exempt Cancer Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Prospective Payment System (PPS)-Exempt Cancer Hospital Quality Reporting (PCHQR) Program currently uses five oncology care measures. The resulting PPS-Exempt...

  11. 77 FR 8860 - Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations

    Science.gov (United States)

    2012-02-15

    ... AGENCY Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations... to control unforeseen pest outbreaks. FOR FURTHER INFORMATION CONTACT: See each emergency exemption... be potentially affected by this action if you are an agricultural producer, food manufacturer,...

  12. Contrasting reduced overshadowing and blocking.

    Science.gov (United States)

    Wheeler, Daniel S; Miller, Ralph R

    2007-07-01

    Preexposure of a cue without an outcome (X-) prior to compound pairings with the outcome (XZ-->O) can reduce overshadowing of a target cue (Z). Moreover, pairing a cue with an outcome (X-->O) before compound training can enhance its ability to compete with another cue (i.e., blocking). Four experiments were conducted in a conditioned bar-press suppression preparation with rats to determine whether spacing of the X- or X-->O trials would differentially affect reduced overshadowing and blocking. Experiment 1a showed that reduced overshadowing was larger with massed trials than with spaced trials. Experiment 1b found that blocking was larger with spaced trials than with massed trials. Experiments 2a and 2b indicated that these effects of trial spacing were both mediated by the associative status of the context at test. The results are interpreted in the framework of contemporary learning theories.

  13. Diversity Gain through Antenna Blocking

    Directory of Open Access Journals (Sweden)

    V. Dehghanian

    2012-01-01

    Full Text Available As part of the typical usage mode, interaction between a handheld receiver antenna and the operator's RF absorbing body and nearby objects is known to generate variability in antenna radiation characteristics through blocking and pattern changes. It is counterintuitive that random variations in blocking can result in diversity gain of practical applicability. This diversity gain is quantified from a theoretical and experimental perspective. Measurements carried out at 1947.5 MHz verify the theoretical predictions, and a diversity gain of 3.1 dB was measured through antenna blocking and based on the utilized measurement setup. The diversity gain can be exploited to enhance signal detectability of handheld receivers based on a single antenna in indoor multipath environments.

  14. Block ground interaction of rockfalls

    Science.gov (United States)

    Volkwein, Axel; Gerber, Werner; Kummer, Peter

    2016-04-01

    During a rockfall the interaction of the falling block with the ground is one of the most important factors that define the evolution of a rockfall trajectory. It steers the rebound, the rotational movement, possibly brake effects, friction losses and damping effects. Therefore, if most reliable rockfall /trajectory simulation software is sought a good understanding of the block ground interaction is necessary. Today's rockfall codes enable the simulation of a fully 3D modelled block within a full 3D surface . However, the details during the contact, i.e. the contact duration, the penetration depth or the dimension of the marks in the ground are usually not part of the simulation. Recent field tests with rocks between 20 and 80 kg have been conducted on a grassy slope in 2014 [1]. A special rockfall sensor [2] within the blocks measured the rotational velocity and the acting accelerations during the tests. External video records and a so-called LocalPositioningSystem deliver information on the travel velocity. With these data not only the flight phases of the trajectories but also the contacts with the ground can be analysed. During the single jumps of a block the flight time, jump length, the velocity, and the rotation are known. During the single impacts their duration and the acting accelerations are visible. Further, the changes of rotational and translational velocity influence the next jump of the block. The change of the rotational velocity over the whole trajectory nicely visualizes the different phases of a rockfall regarding general acceleration and deceleration in respect to the inclination and the topography of the field. References: [1] Volkwein A, Krummenacher B, Gerber W, Lardon J, Gees F, Brügger L, Ott T (2015) Repeated controlled rockfall trajectory testing. [Abstract] Geophys. Res. Abstr. 17: EGU2015-9779. [2] Volkwein A, Klette J (2014) Semi-Automatic Determination of Rockfall Trajectories. Sensors 14: 18187-18210.

  15. 26 CFR 48.4041-20 - Partially exempt methanol and ethanol fuel.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 16 2010-04-01 2010-04-01 true Partially exempt methanol and ethanol fuel. 48... Partially exempt methanol and ethanol fuel. (a) In general. Under section 4041(m), the sale or use of partially exempt methanol or ethanol fuel is taxed at the rate of 41/2 cents per gallon of fuel sold or...

  16. 40 CFR 166.53 - EPA review of crisis exemption and revocation of authority.

    Science.gov (United States)

    2010-07-01

    ... such unreasonable health or environmental risks that the crisis authority should not be exercised or... 40 Protection of Environment 23 2010-07-01 2010-07-01 false EPA review of crisis exemption and... CONDITIONS Crisis Exemptions § 166.53 EPA review of crisis exemption and revocation of authority. (a)...

  17. 40 CFR 180.1282 - Bacillus firmus I-1582; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus firmus I-1582; exemption from... FOOD Exemptions From Tolerances § 180.1282 Bacillus firmus I-1582; exemption from the requirement of a..., for residues of Bacillus firmus I-1582 when used as a soil application or seed treatment....

  18. 40 CFR 180.1128 - Bacillus subtilis MBI 600; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus subtilis MBI 600; exemption... FOOD Exemptions From Tolerances § 180.1128 Bacillus subtilis MBI 600; exemption from the requirement of... biofungicide Bacillus subtilis MBI 600 in or on all food commodities, including residues resulting from...

  19. 40 CFR 180.1202 - Bacillus sphaericus; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus sphaericus; exemption from... FOOD Exemptions From Tolerances § 180.1202 Bacillus sphaericus; exemption from the requirement of a... pesticides, Bacillus sphaericus when used in or on all food crops....

  20. 40 CFR 52.2237 - NOX RACT and NOX conformity exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 4 2010-07-01 2010-07-01 false NOX RACT and NOX conformity exemption... RACT and NOX conformity exemption. Approval. EPA is approving the section 182(f) oxides of nitrogen (NOX) reasonably available control technology (RACT) and NOX conformity exemption request submitted...

  1. 40 CFR 180.1162 - Acrylate polymers and copolymers; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Acrylate polymers and copolymers... RESIDUES IN FOOD Exemptions From Tolerances § 180.1162 Acrylate polymers and copolymers; exemption from the requirement of a tolerance. (a) Acrylate polymers and copolymers are exempt from the requirement of...

  2. 16 CFR 1500.81 - Exemptions for food, drugs, cosmetics, and fuels.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Exemptions for food, drugs, cosmetics, and... § 1500.81 Exemptions for food, drugs, cosmetics, and fuels. (a) Food, drugs, and cosmetics. Substances subject to the Federal Food, Drug, and Cosmetic Act are exempted by section 2(f)(2) of the act; but...

  3. 76 FR 27848 - Pears Grown in Oregon and Washington; Amendment To Allow Additional Exemptions

    Science.gov (United States)

    2011-05-13

    ... provided an exemption for consumer- direct sales of up to 220 pounds of fresh pears per transaction, for... the interim rule that added an exemption for consumer-direct sales of up to 220 pounds of fresh pears..., roadside stands, or farmers' markets. These consumer-direct sales are exempt from the marketing...

  4. 40 CFR 180.1153 - Lepidopteran pheromones; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Lepidopteran pheromones; exemption... FOOD Exemptions From Tolerances § 180.1153 Lepidopteran pheromones; exemption from the requirement of a tolerance. Lepidopteran pheromones that are naturally occurring compounds, or identical or...

  5. 40 CFR 180.1124 - Arthropod pheromones; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Arthropod pheromones; exemption from... FOOD Exemptions From Tolerances § 180.1124 Arthropod pheromones; exemption from the requirement of a tolerance. Arthropod pheromones, as described in § 152.25(b) of this chapter, when used in retrievably...

  6. 40 CFR 180.1057 - Phytophthora palmivora; exemption from requirement of tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Phytophthora palmivora; exemption from... From Tolerances § 180.1057 Phytophthora palmivora; exemption from requirement of tolerance. Phytophthora palmivora is exempted from the requirement of a tolerance in or on the raw agricultural...

  7. 28 CFR 16.99 - Exemption of the Immigration and Naturalization Service Systems-limited access.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of the Immigration and....99 Exemption of the Immigration and Naturalization Service Systems-limited access. (a) The following systems of records of the Immigration and Naturalization Service are exempt from 5 U.S.C. 552a (c) (3)...

  8. 40 CFR 180.1206 - Aspergillus flavus AF36; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Aspergillus flavus AF36; exemption... FOOD Exemptions From Tolerances § 180.1206 Aspergillus flavus AF36; exemption from the requirement of a... pesticide Aspergillus flavus AF36 in or on cotton, gin byproducts; cotton, hulls; cotton, meal;...

  9. 29 CFR 2570.35 - Information to be included in applications for individual exemptions only.

    Science.gov (United States)

    2010-07-01

    ... the exemption transaction has, within the last 13 years, been convicted of any crime described in... each affected plan; (18) The person(s) who will bear the costs of the exemption application and of... exemption transaction and, if so, the names of the persons who will bear the cost of the fee payable to...

  10. 28 CFR 16.93 - Exemption of Tax Division Systems-limited access.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Tax Division Systems-limited... MATERIAL OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.93 Exemption of Tax... systems of records, would enable the subject of an investigation of an actual or potential criminal...

  11. 40 CFR 166.50 - Reporting and recordkeeping requirements for crisis exemption.

    Science.gov (United States)

    2010-07-01

    ... requirements for crisis exemption. 166.50 Section 166.50 Protection of Environment ENVIRONMENTAL PROTECTION... EMERGENCY CONDITIONS Crisis Exemptions § 166.50 Reporting and recordkeeping requirements for crisis... a crisis exemption must be immediately reported to the Agency. (b) Final reports. (1) A...

  12. 40 CFR 180.1258 - Acetic acid; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Acetic acid; exemption from the... Exemptions From Tolerances § 180.1258 Acetic acid; exemption from the requirement of a tolerance. An... acetic acid when used as a preservative on post-harvest agricultural commodities intended for animal...

  13. 76 FR 3646 - Safety Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet Vessels

    Science.gov (United States)

    2011-01-20

    ... SECURITY Coast Guard Safety Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet... Requirements and Manning Exemption Eligibility on Distant Water Tuna Fleet Vessels. All comments received will... availability of a draft policy regarding distant water tuna fleet vessels manning exemption eligibility...

  14. 76 FR 69729 - Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations

    Science.gov (United States)

    2011-11-09

    ... AGENCY Pesticide Emergency Exemptions; Agency Decisions and State and Federal Agency Crisis Declarations... emergency exemptions under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) for use of pesticides as listed in this notice. The exemptions or denials were granted during the period July 1, 2011...

  15. 40 CFR 144.7 - Identification of underground sources of drinking water and exempted aquifers.

    Science.gov (United States)

    2010-07-01

    ... of drinking water and exempted aquifers. 144.7 Section 144.7 Protection of Environment ENVIRONMENTAL... Provisions § 144.7 Identification of underground sources of drinking water and exempted aquifers. (a) The..., except where exempted under paragraph (b) of this section, as an underground source of drinking...

  16. 41 CFR 109-38.204-4 - Report of exempted motor vehicles.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Report of exempted motor..., TRANSPORTATION, AND MOTOR VEHICLES 38-MOTOR EQUIPMENT MANAGEMENT 38.2-Registration, Identification, and Exemptions § 109-38.204-4 Report of exempted motor vehicles. DOE offices shall provide upon request...

  17. 11 CFR 9035.1 - Campaign expenditure limitation; compliance and fundraising exemptions.

    Science.gov (United States)

    2010-01-01

    ... fundraising exemptions. 9035.1 Section 9035.1 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL... expenditure limitation; compliance and fundraising exemptions. (a) Spending limit. (1) No candidate or his or..., fundraising and shortfall bridge loan exemptions. (1) A candidate may exclude from the overall...

  18. 28 CFR 16.105 - Exemption of Foreign Terrorist Tracking Task Force System.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Foreign Terrorist Tracking Task Force System. 16.105 Section 16.105 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.105 Exemption of Foreign Terrorist Tracking Task...

  19. 40 CFR 180.1222 - Sucrose octanoate esters; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sucrose octanoate esters; exemption... FOOD Exemptions From Tolerances § 180.1222 Sucrose octanoate esters; exemption from the requirement of... octanoate esters in or on all food commodities when used in accordance with good agricultural practices....

  20. 75 FR 7303 - Drake Cement, LLC-Acquisition Exemption-Clarkdale Arizona Central Railroad, LLC

    Science.gov (United States)

    2010-02-18

    ... Surface Transportation Board Drake Cement, LLC--Acquisition Exemption--Clarkdale Arizona Central Railroad, LLC Drake Cement, LLC (DC), a noncarrier, has filed a verified notice of exemption under 49 CFR 1150... Docket No. 35351, Drake Switching Company, LLC --Operation Exemption-- Drake Cement, LLC. DC...