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Sample records for blind subterranean mole

  1. Mammalian microevolution in action: adaptive edaphic genomic divergence in blind subterranean mole-rats.

    OpenAIRE

    Polyakov, Andrei; Beharav, Alex; Avivi, Aaron; Nevo, Eviatar

    2004-01-01

    Genomic diversity of anonymous regions across the genome, most probably including coding and noncoding amplified fragment length polymorphisms (AFLPs), was examined in 20 individuals of the blind mole-rat, Spalax galili, one of four allospecies of the Spalax ehrenbergi superspecies of blind subterranean mole-rats in Israel. We compared 10 individuals from two nearby populations in Upper Galilee, separated by only a few dozen to hundreds of metres and living in two sharply contrasting ecologie...

  2. Adaptation of pelage color and pigment variations in Israeli subterranean blind mole rats, Spalax ehrenbergi [corrected].

    Directory of Open Access Journals (Sweden)

    Natarajan Singaravelan

    Full Text Available BACKGROUND: Concealing coloration in rodents is well established. However, only a few studies examined how soil color, pelage color, hair-melanin content, and genetics (i.e., the causal chain synergize to configure it. This study investigates the causal chain of dorsal coloration in Israeli subterranean blind mole rats, Spalax ehrenbergi. METHODS: We examined pelage coloration of 128 adult animals from 11 populations belonging to four species of Spalax ehrenbergi superspecies (Spalax galili, Spalax golani, Spalax carmeli, and Spalax judaei and the corresponding coloration of soil samples from the collection sites using a digital colorimeter. Additionally, we quantified hair-melanin contents of 67 animals using HPLC and sequenced the MC1R gene in 68 individuals from all four mole rat species. RESULTS: Due to high variability of soil colors, the correlation between soil and pelage color coordinates was weak and significant only between soil hue and pelage lightness. Multiple stepwise forward regression revealed that soil lightness was significantly associated with all pelage color variables. Pelage color lightness among the four species increased with the higher southward aridity in accordance to Gloger's rule (darker in humid habitats and lighter in arid habitats. Darker and lighter pelage colors are associated with darker basalt and terra rossa, and lighter rendzina soils, respectively. Despite soil lightness varying significantly, pelage lightness and eumelanin converged among populations living in similar soil types. Partial sequencing of the MC1R gene identified three allelic variants, two of which were predominant in northern species (S. galili and S. golani, and the third was exclusive to southern species (S. carmeli and S. judaei, which might have caused the differences found in pheomelanin/eumelanin ratio. CONCLUSION/SIGNIFICANCE: Darker dorsal pelage in darker basalt and terra rossa soils in the north and lighter pelage in rendzina and

  3. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: Utility and potential for the discovery of novel evolutionary patterns

    KAUST Repository

    Malik, Assaf

    2011-08-12

    The blind subterranean mole rat (Spalax ehrenbergi superspecies) is a model animal for survival under extreme environments due to its ability to live in underground habitats under severe hypoxic stress and darkness. Here we report the transcriptome sequencing of Spalax galili, a chromosomal type of S. ehrenbergi. cDNA pools from muscle and brain tissues isolated from animals exposed to hypoxic and normoxic conditions were sequenced using Sanger, GS FLX, and GS FLX Titanium technologies. Assembly of the sequences yielded over 51,000 isotigs with homology to ~12,000 mouse, rat or human genes. Based on these results, it was possible to detect large numbers of splice variants, SNPs, and novel transcribed regions. In addition, multiple differential expression patterns were detected between tissues and treatments. The results presented here will serve as a valuable resource for future studies aimed at identifying genes and gene regions evolved during the adaptive radiation associated with underground life of the blind mole rat. 2011 Malik et al.

  4. Magnetic compass orientation in the blind mole rat Spalax ehrenbergi.

    Science.gov (United States)

    Kimchi, T; Terkel, J

    2001-02-01

    The blind mole rat Spalax ehrenbergi is a solitary, subterranean rodent that digs and inhabits a system of branching tunnels, with no above-ground exits, which it never leaves unless forced to. To survive, the mole rat must be able to orient efficiently in its tunnel system. The sensory channels available for spatial orientation in the subterranean environment are restricted in comparison with those existing above ground. This study examined the possibility that the mole rat is able to perceive and use the earth's magnetic field to orient in space. Experiments were performed using a device constructed from a pair of electromagnetic 'Helmholtz coils', which create a magnetic field whose direction and strength can be altered. In the first experiment, we tested a group of mole rats (N=33) in an eight-armed maze under the earth's natural magnetic field to determine whether they have directional preferences for the location of their sleeping nest, food chamber and toilet site. A second group of mole rats (N=30) was tested for their directional preference after the earth's magnetic field had been experimentally shifted by 180 degrees. We found that the first group exhibited a significant preference (Pbuild both their sleeping nest and their food store in the southern sector of the maze, whereas the second group shifted the location of their nests (Pbirds, magnetic compass orientation in the mole rat is independent of light stimulation. In the third experiment, we examined whether mole rats (N=24) use the earth's magnetic field as a compass cue to orient in a labyrinth. In the first stage (trials 1-13), the animals were trained to reach a goal box at the end of a complex labyrinth until all individuals had learned the task. In the second stage (trial 14), half the trained mole rats underwent another labyrinth trial under the earth's natural magnetic field, while the other half were tested under a magnetic field shifted by 180 degrees. We found a significant decrease (P<0

  5. Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes

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    Xiaodong Fang

    2014-09-01

    Full Text Available Subterranean mammals spend their lives in dark, unventilated environments that are rich in carbon dioxide and ammonia and low in oxygen. Many of these animals are also long-lived and exhibit reduced aging-associated diseases, such as neurodegenerative disorders and cancer. We sequenced the genome of the Damaraland mole rat (DMR, Fukomys damarensis and improved the genome assembly of the naked mole rat (NMR, Heterocephalus glaber. Comparative genome analyses, along with the transcriptomes of related subterranean rodents, revealed candidate molecular adaptations for subterranean life and longevity, including a divergent insulin peptide, expression of oxygen-carrying globins in the brain, prevention of high CO2-induced pain perception, and enhanced ammonia detoxification. Juxtaposition of the genomes of DMR and other more conventional animals with the genome of NMR revealed several truly exceptional NMR features: unusual thermogenesis, an aberrant melatonin system, pain insensitivity, and unique processing of 28S rRNA. Together, these genomes and transcriptomes extend our understanding of subterranean adaptations, stress resistance, and longevity.

  6. Kinship structure and mating system in a solitary subterranean rodent, the silvery mole-rat

    Czech Academy of Sciences Publication Activity Database

    Patzenhauerová, Hana; Bryja, Josef; Šumbera, R.

    2010-01-01

    Roč. 64, č. 5 (2010), s. 757-767. ISSN 0340-5443 R&D Projects: GA AV ČR IAA601410802 Institutional research plan: CEZ:AV0Z60930519 Keywords : subterranean rodent * kinship structure * mating system * dispersal Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.565, year: 2010

  7. Seismic communication in a blind subterranean mammal: a major somatosensory mechanism in adaptive evolution underground.

    OpenAIRE

    Nevo, E.; Heth, G; Pratt, H

    1991-01-01

    Seismic communication, through low-frequency and patterned substrate-borne vibrations that are generated by head thumping, and which travel long distances underground, is important in the nonvisual communication of subterranean mole rats of the Spalax ehrenbergi superspecies (2n = 52, 54, 58, and 60) in Israel. This importance pertains both intraspecifically in adaptation and interspecifically in speciation. Neurophysiologic, behavioral, and anatomic findings in this study suggest that the me...

  8. The visual system in subterranean African mole-rats (Rodentia, Bathyergidae): Retina, subcortical visual nuclei and primary visual cortex

    Czech Academy of Sciences Publication Activity Database

    Němec, P.; Cveková, P.; Benada, Oldřich; Wielkopolska, E.; Olkowitz, S.; Turlejski, K.; Burda, H.; Bennett, N. C.; Peichl, L.

    2008-01-01

    Roč. 75, 2-4 (2008), s. 356-364. ISSN 0361-9230 Grant ostatní: GA AV ČR(CZ) GA206/06/1469; ZA(ZA) 2069070 Institutional research plan: CEZ:AV0Z50200510 Keywords : microphthalmia * ocular regression * subterranean mammals Subject RIV: EE - Microbiology, Virology Impact factor: 2.281, year: 2008

  9. Effects of Laboratory Housing on Exploratory Behaviour, Novelty Discrimination and Spatial Reference Memory in a Subterranean, Solitary Rodent, the Cape Mole-Rat (Georychus capensis)

    OpenAIRE

    Oosthuizen, Maria Kathleen; Scheibler, Anne-Gita; Charles Bennett, Nigel; Amrein, Irmgard

    2013-01-01

    A large number of laboratory and field based studies are being carried out on mole-rats, both in our research group and others. Several studies have highlighted the development of adverse behaviours in laboratory animals and have emphasised the importance of enrichment for captive animals. Hence we were interested in evaluating how laboratory housing would affect behavioural performance in mole-rats. We investigated exploratory behaviour, the ability to discriminate between novel and familiar...

  10. Effects of laboratory housing on exploratory behaviour, novelty discrimination and spatial reference memory in a subterranean, solitary rodent, the Cape mole-rat (Georychus capensis)

    OpenAIRE

    Oosthuizen, Maria Kathleen; Scheibler, Anne-Gita; Bennett, Nigel Charles; Amrein, Irmgard

    2013-01-01

    A large number of laboratory and field based studies are being carried out on mole-rats, both in our research group and others. Several studies have highlighted the development of adverse behaviours in laboratory animals and have emphasised the importance of enrichment for captive animals. Hence we were interested in evaluating how laboratory housing would affect behavioural performance in mole-rats. We investigated exploratory behaviour, the ability to discriminate between novel and familiar...

  11. Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax.

    Science.gov (United States)

    Li, Kexin; Hong, Wei; Jiao, Hengwu; Wang, Guo-Dong; Rodriguez, Karl A; Buffenstein, Rochelle; Zhao, Yang; Nevo, Eviatar; Zhao, Huabin

    2015-09-22

    Sympatric speciation (SS), i.e., speciation within a freely breeding population or in contiguous populations, was first proposed by Darwin [Darwin C (1859) On the Origins of Species by Means of Natural Selection] and is still controversial despite theoretical support [Gavrilets S (2004) Fitness Landscapes and the Origin of Species (MPB-41)] and mounting empirical evidence. Speciation of subterranean mammals generally, including the genus Spalax, was considered hitherto allopatric, whereby new species arise primarily through geographic isolation. Here we show in Spalax a case of genome-wide divergence analysis in mammals, demonstrating that SS in continuous populations, with gene flow, encompasses multiple widespread genomic adaptive complexes, associated with the sharply divergent ecologies. The two abutting soil populations of S. galili in northern Israel habituate the ancestral Senonian chalk population and abutting derivative Plio-Pleistocene basalt population. Population divergence originated ∼0.2-0.4 Mya based on both nuclear and mitochondrial genome analyses. Population structure analysis displayed two distinctly divergent clusters of chalk and basalt populations. Natural selection has acted on 300+ genes across the genome, diverging Spalax chalk and basalt soil populations. Gene ontology enrichment analysis highlights strong but differential soil population adaptive complexes: in basalt, sensory perception, musculature, metabolism, and energetics, and in chalk, nutrition and neurogenetics are outstanding. Population differentiation of chemoreceptor genes suggests intersoil population's mate and habitat choice substantiating SS. Importantly, distinctions in protein degradation may also contribute to SS. Natural selection and natural genetic engineering [Shapiro JA (2011) Evolution: A View From the 21st Century] overrule gene flow, evolving divergent ecological adaptive complexes. Sharp ecological divergences abound in nature; therefore, SS appears to be an

  12. Living in a ``stethoscope'': burrow-acoustics promote auditory specializations in subterranean rodents

    Science.gov (United States)

    Lange, Simone; Burda, Hynek; Wegner, Regina E.; Dammann, Philip; Begall, Sabine; Kawalika, Mathias

    2007-02-01

    Subterranean mammals rely to a great extent on audition for communication and to be alerted to danger. The only hitherto published report on burrow acoustics revealed that in tunnels of blind mole-rats ( Spalax ehrenbergi), airborne sounds of 440 Hz propagated best whereas lower and higher frequencies were effectively attenuated. Morpho-functional analyses classify the ear of subterranean mammals as a low-sensitivity and low-frequency device. Concordantly, hearing is characterized by low sensitivity and a restricted frequency range tuned to low frequencies (0.5-4 kHz). Some authors considered the restricted hearing in subterranean mammals vestigial and degenerate due to under-stimulation. In contrast to this view stand a rich (mostly low-frequency) vocal repertoire and progressive structural specializations of the middle and inner ear. Thus, other authors considered these hearing characteristics adaptive. To test the hypothesis that acoustical environment in burrows of different species of subterranean mammals is similar, we measured sound attenuation in burrows of Fukomys mole-rats (formerly known as Cryptomys, cf. Kock et al. 2006) of two differently sized species at different locations in Zambia. We show that in these burrows, low-frequency sounds (200-800 Hz) are not only least attenuated but also their amplitude may be amplified like in a stethoscope (up to two times over 1 m). We suggest that hearing sensitivity has decreased during evolution of subterranean mammals to avoid over-stimulation of the ear in their natural environment.

  13. Rhabdochona longleyi sp. n. (Nematoda: Rhabdochonidae) from blind catfishes, Trogloglanis pattersoni and Satan eurystomus (Ictaluridae) from the subterranean waters of Texas.

    Science.gov (United States)

    Moravec, F; Huffman, D G

    1988-01-01

    A new nematode species, Rhabdochona longleyi sp. n. is described from the intestine of two species of blind catfishes, Trogloglanis pattersoni Eigenmann (type host) and Satan eurystomus Hubbs et Bailey (both fam. Ictaluridae, Siluriformes) from the subterranean waters (artesian wells penetrating San Antonio pool of Edwards Aquifer) of Texas, USA. It is characterized largely by the presence of only six anterior teeth in the prostom, simple deirids, by the shape and length of spicules (0.42 to 0.50 mm and 0.093-0.102 mm), shape of the tail tip (rounded), and by filamented eggs. R. longleyi probably adapted to the environment of the aquifer by utilizing available troglobitic crustaceans instead of aquatic insects as an intermediate host. PMID:3198014

  14. Subterranean Termites

    OpenAIRE

    Hodgson, Erin; Roe, Alan H.

    2008-01-01

    Subterranean termites are social insects with a caste system, and belong to the order Isoptera and family Termititae. These termites are closely related to drywood (Kalotermitidae) and dampwood (Termopsidae) termites.

  15. Magnetic orientation in the giant mole-rat and the silvery mole-rat

    OpenAIRE

    OLIVERIUSOVÁ, Ludmila

    2008-01-01

    The magnetic orientation was study in several species of rodents. Aim of this work was verify magnetic sense in two species of subterranean rodents: the giant mole-rat and the silvery mole-rat. A spontaneous directional preference in the magnetic field was tested in circular arena.

  16. Moles (Nevi)

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    ... resources Meet our partners Español Donate Diseases and treatments Acne and rosacea Bumps and growths Color problems Contagious skin diseases ... growths Moles public SPOT Skin Cancer™ Diseases and treatments Acne and rosacea Bumps and growths Keratosis pilaris Moles Seborrheic keratoses ...

  17. Hydatidiform mole

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    ... hands , or unexplained weight loss Symptoms similar to preeclampsia that occur in the first trimester or early ... always a sign of a hydatidiform mole, because preeclampsia is extremely rare this early in a normal ...

  18. Light perception in two strictly subterranean rodents: life in the dark or blue?

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    Ondrej Kott

    Full Text Available BACKGROUND: The African mole-rats (Bathyergidae, Rodentia are strictly subterranean, congenitally microphthalmic rodents that are hardly ever exposed to environmental light. Because of the lack of an overt behavioural reaction to light, they have long been considered to be blind. However, recent anatomical studies have suggested retention of basic visual capabilities. In this study, we employed behavioural tests to find out if two mole-rat species are able to discriminate between light and dark, if they are able to discriminate colours and, finally, if the presence of light in burrows provokes plugging behaviour, which is assumed to have a primarily anti-predatory function. METHODOLOGY/PRINCIPAL FINDING: We used a binary choice test to show that the silvery mole-rat Heliophobius argenteocinereus and the giant mole-rat Fukomys mechowii exhibit a clear photoavoidance response to full-spectrum ("white", blue and green-yellow light, but no significant reaction to ultraviolet or red light during nest building. The mole-rats thus retain dark/light discrimination capabilities and a capacity to perceive short to medium-wavelength light in the photopic range of intensities. These findings further suggest that the mole-rat S opsin has its absorption maximum in the violet/blue part of the spectrum. The assay did not yield conclusive evidence regarding colour discrimination. To test the putative role of vision in bathyergid anti-predatory behaviour, we examined the reaction of mole-rats to the incidence of light in an artificial burrow system. The presence of light in the burrow effectively induced plugging of the illuminated tunnel. CONCLUSION/SIGNIFICANCE: Our findings suggest that the photopic vision is conserved and that low acuity residual vision plays an important role in predator avoidance and tunnel maintenance in the African mole-rats.

  19. Big insights from little animals: allosteric modulation and thermal sensitivity of shrew and mole hemoglobins

    DEFF Research Database (Denmark)

    Campbell, K.L.; Weber, Roy E.

    2007-01-01

    and moles. Despite these constraints, several shrew (and mole) species flourish at elevations exceeding 4500 m (where atmospheric PO2 is < 100 mm Hg), while fossorial moles excavate subterranean burrows in severely hypoxic/hypercapnic soils. As most physiological and morphological traits are likely...

  20. Blindness

    Science.gov (United States)

    ... Got Homework? Here's Help White House Lunch Recipes Blindness KidsHealth > For Kids > Blindness Print A A A ... help, are sometimes called "legally blind." What Causes Blindness? Vision problems can develop before a baby is ...

  1. Blindness

    Science.gov (United States)

    ... Prevalent Cases of Blindness (in thousands) by Age, Gender, and Race/Ethnicity Table for 2010 U.S. Prevalent ... Prevalent Cases of Blindness (in thousands) by Age, Gender, and Race/Ethnicity Table for 2000 U.S. Prevalent ...

  2. Eyes underground: regression of visual protein networks in subterranean mammals.

    Science.gov (United States)

    Emerling, Christopher A; Springer, Mark S

    2014-09-01

    Regressive evolution involves the degeneration of formerly useful structures in a lineage over time, and may be accompanied by the molecular decay of phenotype-specific genes. The mammalian eye has repeatedly undergone degeneration in taxa that occupy dim-light environments including subterranean habitats. Here we assess whether a decrease in the amount of light that reaches the retina is associated with increased regression of retinal genes, whether the phototransduction and visual cycle pathways degrade in a predictable pattern, and if the timing of retinal gene loss is associated with the entrance of mammalian lineages into subterranean environments. Sequence data were obtained from the publically available genomes of the Cape golden mole (Chrysochloris asiatica), naked mole-rat (Heterocephalus glaber) and star-nosed mole (Condylura cristata) for 65 genes associated with phototransduction, the visual cycle, and other retinal functions. Gene sequences were inspected for inactivating mutations and, when present, pseudogene sequences were compared to sequences from subaerial outgroup species. To test whether retinal degeneration is correlated with historical entrances into subterranean environments, estimated dates of retinal gene inactivation were compared to the fossil record and phylogenetic inferences of ancestral fossoriality. Our results show that (1) lower levels of light available to the retina correspond with an increase in the number of retinal pseudogenes, (2) retinal protein networks generally degrade in a predictable manner, although the extensive loss of cone phototransduction genes in Heterocephalus raises further questions regarding SWS1-cone monochromacy versus functional rod monochromacy in this species, and (3) inactivation dates of retinal genes usually post-date inferred entrances into subterranean habitats. PMID:24859681

  3. Subterranean stress engineering experiments

    International Nuclear Information System (INIS)

    The state of stress in a subterranean rock mass has classically been assumed to be constant at best. In soil with a high clay content, preconsolidation and drainage methods can lead to more stable foundation material, but methods for engineering the stresses in large masses of rock are not well known. This paper shows the results from an experiment designed to alter the in situ rock stress field in an oil shale mine. This was done by hydrofracturing the rock by use of a packed-well injection system and then propping the crack open with a thixotropic gel, which slowly hardened to the consistency of cement. Successive hydrofracture and high-pressure grouting resulted in an overstressed region. Well-head injection pressures, surface tilts, injection rates, and subterranean strains were measured and recorded on floppy disk by a Z-80 microprocessor. The results were then transmitted to the large computer system at the Los Alamos Scientific Laboratory (LASL). To put the data in a more useful form, computer-generated movies of the tilts and strains were made by use of computer graphics developed at LASL. The purpose of this paper is to present results from the Single Large Instrumented Test conducted in the Colony Oil Shale Mine near Rifle, Colorado. 13 figures

  4. Genome sequencing reveals insights into physiology and longevity of the naked mole rat

    DEFF Research Database (Denmark)

    Kim, Eun Bae; Fang, Xiaodong; Fushan, Alexey A;

    2011-01-01

    The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordinarily long-lived eusocial mammal. Although it is the size of a mouse, its maximum lifespan exceeds 30 years, making this animal the longest-living rodent. Naked mole rats show negligible senescence, no age......-related increase in mortality, and high fecundity until death. In addition to delayed ageing, they are resistant to both spontaneous cancer and experimentally induced tumorigenesis. Naked mole rats pose a challenge to the theories that link ageing, cancer and redox homeostasis. Although characterized by...... significant oxidative stress, the naked mole rat proteome does not show age-related susceptibility to oxidative damage or increased ubiquitination. Naked mole rats naturally reside in large colonies with a single breeding female, the 'queen', who suppresses the sexual maturity of her subordinates. They also...

  5. MOLES Information Model

    Science.gov (United States)

    Ventouras, Spiros; Lawrence, Bryan; Woolf, Andrew; Cox, Simon

    2010-05-01

    The Metadata Objects for Linking Environmental Sciences (MOLES) model has been developed within the Natural Environment Research Council (NERC) DataGrid project [NERC DataGrid] to fill a missing part of the ‘metadata spectrum'. It is a framework within which to encode the relationships between the tools used to obtain data, the activities which organised their use, and the datasets produced. MOLES is primarily of use to consumers of data, especially in an interdisciplinary context, to allow them to establish details of provenance, and to compare and contrast such information without recourse to discipline-specific metadata or private communications with the original investigators [Lawrence et al 2009]. MOLES is also of use to the custodians of data, providing an organising paradigm for the data and metadata. The work described in this paper is a high-level view of the structure and content of a recent major revision of MOLES (v3.3) carried out as part of a NERC DataGrid extension project. The concepts of MOLES v3.3 are rooted in the harmonised ISO model [Harmonised ISO model] - particularly in metadata standards (ISO 19115, ISO 19115-2) and the ‘Observations and Measurements' conceptual model (ISO 19156). MOLES exploits existing concepts and relationships, and specialises information in these standards. A typical sequence of data capturing involves one or more projects under which a number of activities are undertaken, using appropriate tools and methods to produce the datasets. Following this typical sequence, the relevant metadata can be partitioned into the following main sections - helpful in mapping onto the most suitable standards from the ISO 19100 series. • Project section • Activity section (including both observation acquisition and numerical computation) • Observation section (metadata regarding the methods used to obtained the data, the spatial and temporal sampling regime, quality etc.) • Observation collection section The key concepts in

  6. Genome sequencing reveals insights into physiology and longevity of the naked mole rat

    OpenAIRE

    Kim, Eun Bae; Fang, Xiaodong; Fushan, Alexey A.; Huang, Zhiyong; Lobanov, Alexei V.; Han, Lijuan; Marino, Stefano M.; Sun, Xiaoqing; Turanov, Anton A; Yang, Pengcheng; Yim, Sun Hee; Zhao, Xiang; Kasaikina, Marina V.; Stoletzki, Nina; Peng, Chunfang

    2011-01-01

    The naked mole rat (NMR, Heterocephalus glaber) is a strictly subterranean, extraordinarily long-lived eusocial mammal 1 . Although the size of a mouse, its maximum lifespan exceeds 30 years and makes this animal the longest living rodent. NMRs show negligible senescence, no age-related increase in mortality, and high fecundity until death 2 . In addition to delayed aging, NMRs are resistant to both spontaneous cancer and experimentally induced tumorigenesis 3,4 . NMRs pose a challenge to the...

  7. Trading new neurons for status: Adult hippocampal neurogenesis in eusocial Damaraland mole-rats.

    Science.gov (United States)

    Oosthuizen, M K; Amrein, I

    2016-06-01

    Diversity in social structures, from solitary to eusocial, is a prominent feature of subterranean African mole-rat species. Damaraland mole-rats are eusocial, they live in colonies that are characterized by a reproductive division of labor and a subdivision into castes based on physiology and behavior. Damaraland mole-rats are exceptionally long lived and reproductive animals show delayed aging compared to non-reproductive animals. In the present study, we described the hippocampal architecture and the rate of hippocampal neurogenesis of wild-derived, adult Damaraland mole-rats in relation to sex, relative age and social status or caste. Overall, Damaraland mole-rats were found to have a small hippocampus and low rates of neurogenesis. We found no correlation between neurogenesis and sex or relative age. Social status or caste was the most prominent modulator of neurogenesis. An inverse relationship between neurogenesis and social status was apparent, with queens displaying the lowest neurogenesis while the worker mole-rats had the most. As there is no natural progression from one caste to another, social status within a colony was relatively stable and is reflected in the level of neurogenesis. Our results correspond to those found in the naked mole-rat, and may reflect an evolutionary and environmentally conserved trait within social mole-rat species. PMID:26979050

  8. Convergent and Divergent Adaptations of Subterranean Rodents

    DEFF Research Database (Denmark)

    Fang, Xiaodong

    Subterranean rodents comprise approximately 250 species that spend their entire lives in underground, unventilated tunnels, distributed along all continents except Australia and Antarctica. Subterranean rodents escape from predators and extreme climatic fluctuations in their underground habitats...... systems in the dark; they display remarkable tolerance to a living environment with an excess of carbon dioxide and ammonia, but lack of oxygen; they exhibit extraordinarily long lives, and keep a fantastic resistance to cancer and other aging-associated diseases. In this study, we reported the genomic...... and transcriptomic information of DMR and BMR. By comparing the genomes and transcriptomes of subterranean rodents with that of their aboveground counterparts, we uncovered candidate molecular mechanisms of mammalian adaptation to subterranean environment. The extreme biological features of the NMR...

  9. Unraveling the message: insights into comparative genomics of the naked mole-rat.

    Science.gov (United States)

    Lewis, Kaitlyn N; Soifer, Ilya; Melamud, Eugene; Roy, Margaret; McIsaac, R Scott; Hibbs, Matthew; Buffenstein, Rochelle

    2016-08-01

    Animals have evolved to survive, and even thrive, in different environments. Genetic adaptations may have indirectly created phenotypes that also resulted in a longer lifespan. One example of this phenomenon is the preternaturally long-lived naked mole-rat. This strictly subterranean rodent tolerates hypoxia, hypercapnia, and soil-based toxins. Naked mole-rats also exhibit pronounced resistance to cancer and an attenuated decline of many physiological characteristics that often decline as mammals age. Elucidating mechanisms that give rise to their unique phenotypes will lead to better understanding of subterranean ecophysiology and biology of aging. Comparative genomics could be a useful tool in this regard. Since the publication of a naked mole-rat genome assembly in 2011, analyses of genomic and transcriptomic data have enabled a clearer understanding of mole-rat evolutionary history and suggested molecular pathways (e.g., NRF2-signaling activation and DNA damage repair mechanisms) that may explain the extraordinarily longevity and unique health traits of this species. However, careful scrutiny and re-analysis suggest that some identified features result from incorrect or imprecise annotation and assembly of the naked mole-rat genome: in addition, some of these conclusions (e.g., genes involved in cancer resistance and hairlessness) are rejected when the analysis includes additional, more closely related species. We describe how the combination of better study design, improved genomic sequencing techniques, and new bioinformatic and data analytical tools will improve comparative genomics and ultimately bridge the gap between traditional model and nonmodel organisms. PMID:27364349

  10. Mechanisms of pigmentation loss in subterranean fishes

    Directory of Open Access Journals (Sweden)

    Vanessa Felice

    2008-12-01

    Full Text Available Troglobitic (exclusively subterranean organisms usually present, among their apomorphies related to the subterranean life (troglomorphisms, the regression of eyes and melanic pigmentation. The degree of regression varies among species, from a slight reduction to the complete loss of eyes and dark pigmentation, without a taxonomic correlation. While mechanisms of eye reduction have been intensively investigated in some troglobites such as the Mexican blind tetra characins, genus Astyanax, and the European salamander, Proteus anguinus, few studies have focused on pigmentation. The Brazilian subterranean ichthyofauna distinguishes not only by the species richness (23 troglobitic fishes so far known but also by the variation in the degree of reduction of eyes and pigmentation. This study focused on Brazilian fishes completely devoid of melanic pigmentation: the characiform Stygichthys typhlops (Characidae and the siluriforms Ancistrus formoso (Loricariidae, Rhamdiopsis sp.1 (Heptapteridae; from caves in the Chapada Diamantina, Bahia and Rhamdiopsis sp. 2 (cave in Campo Formoso, Bahia. In order to investigate if such depigmentation is the result of blockage in some step in the melanogenesis, in vitro tests of administration of L-DOPA were done, using caudal-fin fragments extracted from living fish. Except for Rhamdiopsis sp. 2, all the studied species were DOPA(+, i.e., melanin was synthesized after L-DOPA administration. This indicates these fish do have melanophores but they are unable to convert L-tyrosine to L-DOPA. On the other hand, Rhamdiopsis sp. 2, like the albino specimens of Trichomycterus itacarambiensis previously studied (which correspond to one third of the population, are DOPA(-, either because the block of melanin synthesis occurs downstream in melanogenesis, which is probably the case with T. itacarambiensis (monogenic system in view of the phenotypic discontinuity, or because the so-called albinos do no possess melanophores. The

  11. Of Bushwahckers, Termites and Moles.

    Science.gov (United States)

    Smelter, Richard W.

    2003-01-01

    Retired school administrator describes five types of school personnel that make an administrator's job difficult: Bushwackers, termites, CIA moles, rumor-mill addicts, and sartorial slobs. For example, termites are staff members who purposely volunteer for committees so they can sabotage the group's efforts from within. (PKP)

  12. Moles

    Science.gov (United States)

    ... Derm App Skin Facts Aging and Sun Damage Beauty Myths Preventing Sun Damage Skin Cancer Detection Skin ... done where cancer is a reasonable concern. Improving cosmetic appearance is another reason for excision, but all ...

  13. Partial hydatidiform mole: ultrasonographic features.

    Science.gov (United States)

    Woo, J S; Hsu, C; Fung, L L; Ma, H K

    1983-05-01

    Four patients with partial hyatidiform mole managed at the Queen Mary Hospital, Hong Kong, are described. The diagnosis of blighted ovum or missed abortion was made on the sonographic findings prior to suction evacuation. The dominant features in these cases consisted of a relatively large central transonic area bearing the appearance of an empty gestational sac and surrounded by a thick rim of low-level placenta-like echoes; in contrast with the case of the blighted ovum, a well-defined echogenic sac wall is absent. In another 9 patients with molar pregnancy managed during the same period, the more typical 'snow-storm' vesicular appearance was present. It was concluded that the anembryonic appearance described should alert the sonologist and clinician to the possible diagnosis of partial hydatitiform mole. The evacuated material from the uterine cavity should be examined morphologically and if possible cytogenetically. PMID:6578773

  14. Family Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis.

    Science.gov (United States)

    Davies, Kalina T J; Bennett, Nigel C; Tsagkogeorga, Georgia; Rossiter, Stephen J; Faulkes, Christopher G

    2015-12-01

    During their evolutionary radiation, mammals have colonized diverse habitats. Arguably the subterranean niche is the most inhospitable of these, characterized by reduced oxygen, elevated carbon dioxide, absence of light, scarcity of food, and a substrate that is energetically costly to burrow through. Of all lineages to have transitioned to a subterranean niche, African mole-rats are one of the most successful. Much of their ecological success can be attributed to a diet of plant storage organs, which has allowed them to colonize climatically varied habitats across sub-Saharan Africa, and has probably contributed to the evolution of their diverse social systems. Yet despite their many remarkable phenotypic specializations, little is known about molecular adaptations underlying these traits. To address this, we sequenced the transcriptomes of seven mole-rat taxa, including three solitary species, and combined new sequences with existing genomic data sets. Alignments of more than 13,000 protein-coding genes encompassed, for the first time, all six genera and the full spectrum of ecological and social variation in the clade. We detected positive selection within the mole-rat clade and along ancestral branches in approximately 700 genes including loci associated with tumorigenesis, aging, morphological development, and sociality. By combining these results with gene ontology annotation and protein-protein networks, we identified several clusters of functionally related genes. This family wide analysis of molecular evolution in mole-rats has identified a suite of positively selected genes, deepening our understanding of the extreme phenotypic traits exhibited by this group. PMID:26318402

  15. Tool to Distinguish Moles from Melanoma

    Science.gov (United States)

    Moles to Melanoma: Recognizing the ABCDE Features” presents photos that show changes in individual pigmented lesions over time, and describes the different appearances of moles, dysplastic nevi, and melanomas.

  16. Diatom flora in subterranean ecosystems: a review

    Directory of Open Access Journals (Sweden)

    Elisa Falasco

    2014-09-01

    Full Text Available In scarcity of light and primary producers, subterranean ecosystems are generally extremely oligotrophic habitats, receiving poor supplies of degradable organic matter from the surface. Human direct impacts on cave ecosystems mainly derive from intensive tourism and recreational caving, causing important alterations to the whole subterranean environment. In particular, artificial lighting systems in show caves support the growth of autotrophic organisms (the so-called lampenflora, mainly composed of cyanobacteria, diatoms, chlorophytes, mosses and ferns producing exocellular polymeric substances (EPSs made of polysaccharides, proteins, lipids and nucleic acids. This anionic EPSs matrix mediates to the intercellular communications and participates to the chemical exchanges with the substratum, inducing the adsorption of cations and dissolved organic molecules from the cave formations (speleothems. Coupled with the metabolic activities of heterotrophic microorganisms colonising such layer (biofilm, this phenomenon may lead to the corrosion of the mineral surfaces. In this review, we investigate the formation of biofilms, especially of diatom-dominated ones, as a consequence of artificial lighting and its impacts on speleothems. Whenever light reaches the subterranean habitat (both artificially and naturally a relative high number of species of diatoms may indeed colonise it. Cave entrances, artificially illuminated walls and speleothems inside the cave are generally the preferred substrates. This review focuses on the diatom flora colonising subterranean habitats, summarizing the information contained in all the scientific papers published from 1900 up to date. In this review we provide a complete checklist of the diatom taxa recorded in subterranean habitats, including a total of 363 taxa, belonging to 82 genera. The most frequent and abundant species recorded in caves and other low light subterranean habitats are generally aerophilic and

  17. Survey of subterranean termite (Isoptera: Rhinotermitidae) utilization of temperate forests

    Science.gov (United States)

    Both native and invasive subterranean termites (Isoptera: Rhinotermitidae), including the Formosan subterranean termite, are well known pests of urban areas, but little is known about their distribution or impact in forest ecosystems of the southeastern United States. Recently harvested timber stump...

  18. CT findings of the Hydatidiform mole

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Kyung Sik; Yoo, Shi Joon; Chang, June Hong [Seoul District Armed Forces General Hospital, Seoul (Korea, Republic of)

    1984-09-15

    Even though ultrasonography is a primary tool for evaluation of gynecological pelvic mass, CT can be helpful when ultrasonography is suboptimal either because of abundant intestinal gas or marked obesity. Authors experienced 3 cases of hydatidiform mole demonstrated by CT. The findings of hydatidiform mole are enlargement of uterus, low density in the uterine cavity, irregular soft tissue mass with small multiple cyst, and strong contrast enhancement of the soft tissue mass within the uterine cavity. CT can be a useful diagnostic tool for differentiation of hydatidiform mole from choriocarcinoma because of good visualization of uterine wall and pelvic structures.

  19. Photic induction of Fos in the suprachiasmatic nucleus of African mole-rats: responses to increasing irradiance.

    Science.gov (United States)

    Oosthuizen, Maria K; Bennett, Nigel C; Cooper, Howard M

    2010-09-01

    African mole-rats (family Bathyergidae) are strictly subterranean rodent species that are rarely exposed to environmental light. Morphological and physiological adaptations to the underground environment include a severely reduced eye size and regressed visual system. Responses of the circadian system to light, however, appear to be intact, since mole-rats are able to entrain their circadian activity rhythms to the light-dark cycle and light induces Fos expression in the suprachiasmatic nucleus (SCN). Social organization varies from solitary species to highly elaborated eusocial structures, characterized by a distinct division of labor and in which one reproductive female regulates the behavior and reproductive physiology of other individuals in the colony. The authors studied light-induced Fos expression in the SCN to increasing light intensities in four mole-rat species, ranging from strictly solitary to highly social. In the solitary Cape mole-rat, light induces significant Fos expression in the SCN, and the number of Fos-immunopositive cells increases with increasing light intensity. In contrast, Fos induction in the SCN of social species was slightly greater than, but not statistically different from, the dark-control animals as is typical of most rodents. One species showed a trend for an increase in expression with increased light, whereas a second species showed no trend in expression. In the naked mole-rat, Fos expression appeared higher in the dark-controls than in the animals exposed to light, although the differences in Fos expression were not significant. These results suggest a gradient in the sensitivity of the circadian system to light in mole-rats, with a higher percentage of individuals that are unresponsive to light in correlation with the degree of sociality. In highly social species, such as the naked mole-rat that live in a relatively stable subterranean milieu in terms of food availability, temperature, constant darkness, and devoid of 24-h

  20. The subterranean war on science?: a comment

    OpenAIRE

    Pearce, Warren

    2013-01-01

    Last week saw the publication of an article entitled “The Subterranean War on Science” in the Association of Psychological Science’s Observer magazine. The authors – scientists from a range of disciplines – reflect on their experiences of their work becoming noticed in public. In particular, they argue that the harassment, bullying and abuse of scientists constitute a ‘war on science’ which should be publicised, with a view to “enable lawmakers to improve the balance between academic freedom ...

  1. Digital dissection of the masticatory muscles of the naked mole-rat, Heterocephalus glaber (Mammalia, Rodentia

    Directory of Open Access Journals (Sweden)

    Philip G. Cox

    2014-06-01

    Full Text Available The naked mole-rat, Heterocephalus glaber, of the family Bathyergidae is a subterranean rodent that feeds on underground roots and tubers and digs extensive tunnel systems with its incisors. It is a highly unusual mammal with regard to its social structure, longevity, pain insensitivity and cancer resistance, all of which have made it the subject of a great deal of research in recent years. Yet, much of the basic anatomy of this species remains undocumented. In this paper, we describe the morphology of the jaw-closing musculature of the naked mole-rat, as revealed by contrast-enhanced micro-computed tomography. This technique uses an iodine stain to enable the imaging of soft tissues with microCT. The iodine-enhanced scans were used to create 3D reconstructions of the naked mole-rat masticatory muscles from which muscle masses were calculated. The jaw-closing musculature of Heterocephalus glaber is relatively very large compared to other rodents and is dominated by the superficial masseter, the deep masseter and the temporalis. The temporalis in particular is large for a rodent, covering the entirety of the braincase and much of the rear part of the orbit. The morphology of the masseter complex described here differs from two other published descriptions of bathyergid masticatory muscles, but is more similar to the arrangement seen in other rodent families. The zygomaticomandibularis (ZM muscle does not protrude through the infraorbital foramen on to the rostrum and thus the naked mole-rat should be considered protrogomorphous rather than hystricomorphous, and the morphology is consistent with secondarily lost hystricomorphy as has been previously suggested for Bathyergidae. Overall, the morphology of the masticatory musculature indicates a species with a high bite force and a wide gape–both important adaptations for a life dominated by digging with the incisors.

  2. Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

    Science.gov (United States)

    Baker, Sandra E.; Ellwood, Stephen A.; Johnson, Paul J.; Macdonald, David W.

    2016-01-01

    Simple Summary Moles are burrowing mammals that are regarded as pests in Britain, and until 2006 they could legally be killed using strychnine poison. When strychnine was withdrawn there were fears that mole populations would increase. We surveyed farmers, amenity managers and householders about moles and mole control on their land in 2007, post strychnine withdrawal. Kill-trapping was by far the preferred control method used and control may be used more than can be justified by damage levels or the effect of control on damage. Mole traps are unregulated, unlike most other spring traps, and some might not meet current welfare standards. We found no evidence that mole activity had increased since a 1992 survey of farms. Abstract Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we conducted a comprehensive, nationwide survey of land manager perceptions, opinions and behaviour regarding moles and mole control on farms, amenities and domestic gardens in Britain. We surveyed 2150 land managers (achieving a 59% response rate) and ground-truthed 29 responses. Moles were reported to be present on most farms and amenities, and 13% of gardens, and were more common in lighter soils. Where present, moles were usually considered pests, this being more likely in Wales, Scotland and northern England, on livestock and mixed farms, and on large, high-value amenities, e.g., racecourses and golf courses. Mole control followed similar patterns to mole presence. More control may occur than is economically, and therefore potentially ethically, justified. Control should be more carefully considered and, where necessary, more effectively targeted. Kill

  3. Moles and Mole Control on British Farms, Amenities and Gardens after Strychnine Withdrawal

    Directory of Open Access Journals (Sweden)

    Sandra E. Baker

    2016-06-01

    Full Text Available Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we conducted a comprehensive, nationwide survey of land manager perceptions, opinions and behaviour regarding moles and mole control on farms, amenities and domestic gardens in Britain. We surveyed 2150 land managers (achieving a 59% response rate and ground-truthed 29 responses. Moles were reported to be present on most farms and amenities, and 13% of gardens, and were more common in lighter soils. Where present, moles were usually considered pests, this being more likely in Wales, Scotland and northern England, on livestock and mixed farms, and on large, high-value amenities, e.g., racecourses and golf courses. Mole control followed similar patterns to mole presence. More control may occur than is economically, and therefore potentially ethically, justified. Control should be more carefully considered and, where necessary, more effectively targeted. Kill-trapping was the favoured recent and future method on farms and amenities, even if strychnine was to be reintroduced; however, because mole traps are currently unregulated, some might not meet current welfare standards if tested. We found no evidence for an increase in moles since a farm questionnaire survey conducted in 1992; this could have wider implications for future wildlife management policy changes.

  4. Nootkatone is a repellent for Formosan subterranean termite (Coptotermes formosanus).

    Science.gov (United States)

    Zhu, B C; Henderson, G; Chen, F; Maistrello, L; Laine, R A

    2001-03-01

    We examined the behavior of Formosan subterranean termites toward one of the components of vetiver grass oil, the roots of which manufacture insect repellents. We found nootkatone, a sesquiterpene ketone, isolated from vetiver oil is a strong repellent and toxicant to Formosan subterranean termites. The lowest effective concentration tested was 10 micrograms/g substrate. This is the first report of nootkatone being a repellent to insects. PMID:11441443

  5. Brain Mass and Cranial Nerve Size in Shrews and Moles

    OpenAIRE

    Leitch, Duncan B.; Sarko, Diana K.; Catania, Kenneth C.

    2014-01-01

    We investigated the relationship between body size, brain size, and fibers in selected cranial nerves in shrews and moles. Species include tiny masked shrews (S. cinereus) weighing only a few grams and much larger mole species weighing up to 90 grams. It also includes closely related species with very different sensory specializations – such as the star-nosed mole and the common, eastern mole. We found that moles and shrews have tiny optic nerves with fiber counts not correlated with body or ...

  6. Effect of chemical cues on the foraging and tunneling behavior of Formosan subterranean termites (Isoptera: Rhinotermitidae)

    Science.gov (United States)

    Wood rot fungi can cause directional tunneling, aggregation behavior and increased wood consumption by subterranean termites. Because vanillin and guaiacol are byproducts of lignin degradation, these chemicals were tested as potential attractants to Formosan subterranean termites, Coptotermes formo...

  7. Willed blindness

    DEFF Research Database (Denmark)

    Gjerris, Mickey

    2015-01-01

    This article describes how we seem to live in a willed blindness towards the effects that our meat production and consumption have on animals, the environment and the climate. A willed blindness that cannot be explained by either lack of knowledge or scientific uncertainty. The blindness enables us...... willed blindness focusing on the development of either a new moral vision of our obligations or new visions of what a good life is....

  8. Ossicular density in golden moles (Chrysochloridae).

    Science.gov (United States)

    Mason, Matthew J; Lucas, Sarah J; Wise, Erica R; Stein, Robin S; Duer, Melinda J

    2006-12-01

    The densities of middle ear ossicles of golden moles (family Chrysochloridae, order Afrosoricida) were measured using the buoyancy method. The internal structure of the malleus was examined by high-resolution computed tomography, and solid-state NMR was used to determine relative phosphorus content. The malleus density of the desert golden mole Eremitalpa granti (2.44 g/cm3) was found to be higher than that reported in the literature for any other terrestrial mammal, whereas the ossicles of other golden mole species are not unusually dense. The increased density in Eremitalpa mallei is apparently related both to a relative paucity of internal vascularization and to a high level of mineralization. This high density is expected to augment inertial bone conduction, used for the detection of seismic vibrations, while limiting the skull modifications needed to accommodate the disproportionately large malleus. The mallei of the two subspecies of E. granti, E. g. granti and E. g. namibensis, were found to differ considerably from one another in both size and shape. PMID:16944164

  9. Color Blindness

    Institute of Scientific and Technical Information of China (English)

    严双红

    2007-01-01

    About one in 12 boys is color-blind, and one in every 400 girls, so in each school class there are likely to be at least one or two people who are color-blind. Because they are color- blind from birth, most people do not know that they are color-

  10. Prevalence of Toxoplasma gondii in common moles (Talpa europaea)

    NARCIS (Netherlands)

    Krijger, I.M.; Cornelissen, J.B.W.J.; Wisselink, H.J.; Meerburg, B.G.

    2014-01-01

    Background The prevalence of Toxoplasma gondii in common moles, Talpa europaea, was investigated in order to determine whether moles can serve as an indicator species for T. gondii infections in livestock. Findings In total, 86 moles were caught from 25 different sites in the Netherlands. Five diffe

  11. PARTIAL HYDATIDIFORM MOLE WITH A LIVE FETUS: A RARE ENTITY

    Directory of Open Access Journals (Sweden)

    Mounika Reddy

    2015-07-01

    Full Text Available BACKGROUND : Gestational trophoblastic neoplasia (GTN represents a spectrum of premalignant and malignant diseases that occur after abnormal fertilization. [ 1 ] GTN includes complete hydatidiform mole (CHM, partial hydatidiform mole (PHM, invasive mole, choriocarcinoma, and placental - site trophoblastic tumor (PSTT. CHM and PHM together account for 80% of all cases of GTN.

  12. Partial hydatidiform mole: histologic parameters in correlation with DNA genotyping.

    Science.gov (United States)

    Buza, Natalia; Hui, Pei

    2013-05-01

    Histologic diagnosis of partial hydatidiform mole (PHM) continues to be problematic, and DNA genotyping has recently become cost-effective for precise separation of PHM from its mimics. We performed a comprehensive reevaluation of histologic parameters of PHM in correlation with DNA genotyping. A total of 143 early abortion specimens were subjected to genotyping as part of the routine workup, resulting in 60 cases of PHM, 52 cases of various chromosomal trisomies, and 31 cases of nonmolar diploid gestations. All available hematoxylin and eosin slides were reviewed retrospectively by 2 gynecologic pathologists blinded to the genotyping results. Significant histologic overlaps were present among genetically confirmed PHM, hydropic abortions, and chromosomal trisomy syndromes. The following morphologic parameters emerged with diagnostic significance for PHM: villus size, presence of 2 villous populations, round or oval pseudoinclusions, at least moderate villous hydrops, cistern formation, and trophoblastic hyperplasia. The most sensitive morphologic features for PHM included villous hydrops (86% sensitivity) or the presence of at least 1 of the following 3 parameters: 2 villous populations, round or oval pseudoinclusions, and cisterns (84% sensitivity). The presence of cisterns and villous size ≥2.5 mm had the highest positive predictive value (90%) for PHM. In conclusion, no single or combined morphologic features are sufficient for definitive diagnosis of PHM. The presence of any one of the following histologic findings should prompt DNA genotyping workup to rule out PHM: round or oval pseudoincludions, cistern formation, 2 populations of villi, and a villous size of ≥2.5 mm. PMID:23518914

  13. Invasive mole: a rare cause of postmenopausal bleeding

    Directory of Open Access Journals (Sweden)

    Mamour Guèye

    2013-06-01

    Full Text Available Gestational trophoblastic disease (GTD describes a number of gynaecological tumours that originate in the trophoblast layer, including hydatidiform mole (complete or partial, placental site trophoblastic tumour, choriocarcinoma and invasive mole. Invasive moles are responsible of most cases of localized gestational trophoblastic neoplasia (GTN. Invasive mole is a condition where a molar pregnancy, such as a partial hydatidiform mole or complete hydatidiform mole, invades the wall of the uterus. It is an extremely rare condition. As GTN is not considered in the differential diagnosis of postmenopausal uterine malignancies, its preoperative diagnosis is challenging. We report a case of invasive hydatidiform mole in a postmenopausal woman discovered in a context of postmenopausal bleeding. She underwent hysterectomy and followed up till her beta hCG levels were within normal limits. The patient is in complete remission in the first postoperative year. [Int J Reprod Contracept Obstet Gynecol 2013; 2(3.000: 451-453

  14. Ultrasonographic findings of hydatidiform mole and missed abortion

    International Nuclear Information System (INIS)

    To establish the sonographic characteristics of the hydatidiform mole and the missed abortion with placental degeneration, we have retrospectively analyzed 12 cases of complete mole, 10 cases of partial mole, and 10 cases of missed abortion with placental hydropic degeneration, collected at Taegu Catholic General Hospital, from January 1986 to December 1989. The results were as follows : 1. Of 12 cases of complete mole, all demonstrated diffuse intrauterine vesicular pattern of internal echo without a gestational sac. Two cases were recurred after D and E. 2. The partial mole was characterized by focal (70%) or diffuse (20%) distribution of hydatidiform placental change and a gestational sac (100%) with or without a macerated fetus. But the striking hydatidiform placental change was not present in one cases of partial mole. 3. The uterus was larger for dates in 9 cases (90%) of complete mole, but smaller for dates in 7 cases (70%) of partial mole. 4. The missed abortion with placental hydropic degeneration was indistinguished from a partial mole due to their similar sonographic appearance : focal or diffuse cystic change of a placenta, a distorted gestational sac with or without a fetus, and a smaller uterus for dates. On conclusion, the complete mole could be easily distinguished from a partial mole or a missed abortion by sonography : a gestational sac or an area of noncystic placenta was not identified in a complete mole. The partial mole was indistinguished from a missed abortion, but if there is the suspicion of trophoblastic proliferation, such as a convex placental surface or a larger uterus for dates, then the diagnosis is probably a partial mole rather than a missed abortion

  15. Formosan Subterranean Termites in the Continental United States

    Science.gov (United States)

    The Formosan subterranean termite Coptotermes formosanus Shriaki (FST) was introduced into the United States from Asia following World War II, through ports in Galveston, TX, Lake Charles and New Orleans, LA, and Charleston, SC. Populations in this country were first correctly identified in the 196...

  16. Localized vibrations: moles in structure-land

    Science.gov (United States)

    van der Maas, John H.

    1992-03-01

    Functional groups reveal specific information about their direct surroundings; in fact, they form the moles, the undercover agents, in molecules. However, as with agents, the information is produced in coded form (spectral data) so one has to know the code in detail before the message is completely understood. The substantially improved accuracy (wavenumber, intensity) and sensitivity brought about by FT-instruments, in combination with computer software, offer extended spectral information. Functional groups can now be examined in great detail. Obviously the amount of deducible structural items is group dependent, implying that one has to pursue the probing qualities of a functionality prior to use. The OH-group, and more in particular the OH-stretching vibration, proves to be an extremely good mole. Its potentials are demonstrated on conformational studies of various saturated alcohols, the presence of OH(DOT)(DOT)(DOT)(pi) bridges, the strength and type of OH(DOT)(DOT)(DOT)O bridges, all in an apolar solvent, and on the disclosure of different hydrogen bonds in some solid samples.

  17. The risk of persistent trophoblastic disease after hydatidiform mole classified by morphology and ploidy

    DEFF Research Database (Denmark)

    Niemann, Isa; Hansen, Estrid S; Sunde, Lone

    2007-01-01

    OBJECTIVE: Hydatidiform mole can be classified by histopathologic characteristics and by genetic constitutions and most complete moles are diploid, whereas most partial moles are triploid. We investigated the concordance between these two classifications, characterized moles with conflicting clas...

  18. Ectoparasite Burdens of the Damaraland Mole-Rat (Fukomys damarensis) from Southern Africa.

    Science.gov (United States)

    Lutermann, Heike; Carpenter-Kling, Tegan; Ueckermann, Edward A; Gutjahr, Gundula; Bennett, Nigel C

    2015-12-01

    Damaraland mole-rats (Fukomys damarensis) of the family Bathyergidae are widely distributed subterranean rodents in sub-Saharan Africa. No parasites have ever been reported for this species and only 1 ectoparasite is described for the entire genus. In the current study ectoparasites were collected from individuals captured at 3 localities in South Africa and Namibia to document the ectoparasite community of F. damarensis, investigate their aggregation patterns, and evaluate the influence of season on ectoparasite burden. A total of 2,071 arthropods from 9 mite taxa and 1 louse species (Eulinognathus hilli) were collected from 293 hosts sampled. Of these, 5 mite species (Androlaelaps scapularis, Androlaelaps capensis, Androlaelaps tauffliebi, Radfordia sp., and unidentified chiggers) and the louse were parasites while the remainder was soil mites. All ectoparasites were highly aggregated and the species richness as well as the prevalence and abundance of 4 of them were significantly greater in summer compared to winter, possibly as a result of seasonal changes in rainfall patterns affecting the ectoparasites, host behavior, or both. PMID:26249137

  19. The enemy below: preparing ground forces for subterranean warfare

    OpenAIRE

    Bowes, Joshua S.; Newdigate, Mark T.; Rosario, Pedro J.; Tindoll, Davis D.

    2013-01-01

    Approved for public release; distribution is unlimited. This capstone project analyses subterranean threats in the contemporary operational environment. It identifies the doctrinal gap in the U.S. military regarding operations within tunnels, urban and natural cavities, and other underground facilities, and outlines the changes necessary to prepare ground forces to operate in these complex environments. This paper reviews historical cases spanning back over half a millennium, proposes a ne...

  20. Colonization of subterranean habitats by spiders in Central Europe

    Czech Academy of Sciences Publication Activity Database

    Růžička, Vlastimil; Šmilauer, P.; Mlejnek, R.

    2013-01-01

    Roč. 42, č. 2 (2013), s. 133-140. ISSN 0392-6672 Grant ostatní: GA JU(CZ) GAJU 04-142/2010/P Institutional support: RVO:60077344 Keywords : superficial and deep subterranean habitats * caves * spiders Subject RIV: EH - Ecology, Behaviour Impact factor: 1.275, year: 2013 http://scholarcommons.usf.edu/cgi/viewcontent.cgi?article=1288&context=ijs

  1. Polymers for subterranean containment barriers for underground storage tanks (USTs)

    International Nuclear Information System (INIS)

    The US Department of Energy (DOE) set up the Underground Storage Tank Integrated Demonstration Program (USTID) to demonstrate technologies for the retrieval and treatment of tank waste, and closure of underground storage tanks (USTs). There are more than 250 underground storage tanks throughout the DOE complex. These tanks contain a wide variety of wastes including high level, low level, transuranic, mixed and hazardous wastes. Many of the tanks have performed beyond the designed lifetime resulting in leakage and contamination of the local geologic media and groundwater. To mitigate this problem it has been proposed that an interim subterranean containment barrier be placed around the tanks. This would minimize or prevent future contamination of soil and groundwater in the event that further tank leakages occur before or during remediation. Use of interim subterranean barriers can also provide sufficient time to evaluate and select appropriate remediation alternatives. The DOE Hanford site was chosen as the demonstration site for containment barrier technologies. A panel of experts for the USTID was convened in February, 1992, to identify technologies for placement of subterranean barriers. The selection was based on the ability of candidate grouts to withstand high radiation doses, high temperatures and aggressive tank waste leachates. The group identified and ranked nine grouting technologies that have potential to place vertical barriers and five for horizontal barriers around the tank. The panel also endorsed placement technologies that require minimal excavation of soil surrounding the tanks

  2. Moles: Tool-Assisted Environment Isolation with Closures

    Science.gov (United States)

    de Halleux, Jonathan; Tillmann, Nikolai

    Isolating test cases from environment dependencies is often desirable, as it increases test reliability and reduces test execution time. However, code that calls non-virtual methods or consumes sealed classes is often impossible to test in isolation. Moles is a new lightweight framework which addresses this problem. For any .NET method, Moles allows test-code to provide alternative implementations, given as .NET delegates, for which C# provides very concise syntax while capturing local variables in a closure object. Using code instrumentation, the Moles framework will redirect calls to provided delegates instead of the original methods. The Moles framework is designed to work together with the dynamic symbolic execution tool Pex to enable automated test generation. In a case study, testing code programmed against the Microsoft SharePoint Foundation API, we achieved full code coverage while running tests in isolation without an actual SharePoint server. The Moles framework integrates with .NET and Visual Studio.

  3. EFFECTS OF HABITAT CHARACTERIZATION ON THE ABUNDANCE AND ACTIVITY OF SUBTERRANEAN TERMITES IN ARID SOUTHEASTERN NEW MEXICO

    Science.gov (United States)

    Amitermes wheeleri was the most abundant termite species in most of the habitats. Gnathamitermes tubiformans was the most abundant subterranean termite species in habitats dominated by creosotebush, Larrea tridentata. Subterranean termite abundance measured by numbers of termit...

  4. A novel strain of Steinernema riobrave (Rhabditida: Steinernematidae) possesses superior virulence to subterranean termites (Isoptera:Rhinotermitidae)

    Science.gov (United States)

    Subterranean termites are major global pests of wood structures and wood products. Among the most economically important subterranean termite species in the US are Heterotermes aureus, Reticulitermes flavipes, and Coptotermes formosanus. In prior studies, the entomopathogenic nematode, Steinernema...

  5. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm--Spermiogram and Functional Testicular Morphology of Fukomys anselli.

    Directory of Open Access Journals (Sweden)

    Angelica Garcia Montero

    Full Text Available Ansell's mole-rats (Fukomys anselli are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography of breeders compared to non-breeders (with body mass having a significant effect. There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations, however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female ("provoked or induced dispersal". Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly

  6. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm--Spermiogram and Functional Testicular Morphology of Fukomys anselli.

    Science.gov (United States)

    Garcia Montero, Angelica; Vole, Christiane; Burda, Hynek; Malkemper, Erich Pascal; Holtze, Susanne; Morhart, Michaela; Saragusty, Joseph; Hildebrandt, Thomas B; Begall, Sabine

    2016-01-01

    Ansell's mole-rats (Fukomys anselli) are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression) we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography) of breeders compared to non-breeders (with body mass having a significant effect). There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations), however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female ("provoked or induced dispersal"). Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly increased testes

  7. Non-Breeding Eusocial Mole-Rats Produce Viable Sperm—Spermiogram and Functional Testicular Morphology of Fukomys anselli

    Science.gov (United States)

    Garcia Montero, Angelica; Vole, Christiane; Burda, Hynek; Malkemper, Erich Pascal; Holtze, Susanne; Morhart, Michaela; Saragusty, Joseph; Hildebrandt, Thomas B.; Begall, Sabine

    2016-01-01

    Ansell’s mole-rats (Fukomys anselli) are subterranean rodents living in families composed of about 20 members with a single breeding pair and their non-breeding offspring. Most of them remain with their parents for their lifetime and help to maintain and defend the natal burrow system, forage, and care for younger siblings. Since incest avoidance is based on individual recognition (and not on social suppression) we expect that non-breeders produce viable sperm spontaneously. We compared the sperm of breeding and non-breeding males, obtained by electroejaculation and found no significant differences in sperm parameters between both groups. Here, we used electroejaculation to obtain semen for the first time in a subterranean mammal. Spermiogram analysis revealed no significant differences in sperm parameters between breeders and non-breeders. We found significantly larger testes (measured on autopsies and on living animals per ultrasonography) of breeders compared to non-breeders (with body mass having a significant effect). There were no marked histological differences between breeding and non-breeding males, and the relative area occupied by Leydig cells and seminiferous tubules on histological sections, respectively, was not significantly different between both groups. The seminiferous epithelium and to a lesser degree the interstitial testicular tissue are characterized by lesions (vacuolar degenerations), however, this feature does not hinder fertilization even in advanced stages of life. The continuous production of viable sperm also in sexually abstinent non-breeders might be best understood in light of the mating and social system of Fukomys anselli, and the potential to found a new family following an unpredictable and rare encounter with an unfamiliar female (“provoked or induced dispersal”). Apparently, the non-breeders do not reproduce because they do not copulate but not because they would be physiologically infertile. The significantly increased

  8. Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization

    OpenAIRE

    Zhou, Xi; Chen, Yongli; Li, Yongmei; DUAN, ZHAO

    2011-01-01

    In the present study, the case of a 34-year-old Chinese female who underwent in vitro fertilization resulting in a twin pregnancy was reported. Following in vitro fertilization, the patient was found to have a partial hydatidiform mole (PHM) with a co-existing twin by transvaginal sonography (TVS). At 16 weeks, the pregnancy was terminated and a normal-looking fetus with a HM placenta was delivered, in addition to a normal fetus with a normal placenta. Following termination of the pregnancy, ...

  9. CLINICAL PARTICULARITIES AND DIAGNOSTIC METHODS IN THE HYDATIDIFORM MOLE

    Directory of Open Access Journals (Sweden)

    Eduard Crauciuc

    2013-12-01

    Full Text Available Aim of this study was to establish a significant way to the prognosis improvement in trophoblastic pathologyin patients with hydatidiform mole. Objective. A mole is a particularity of embryonic development where a pregnancyoccurs paradoxically without an embryo (the mole pregnancy and develops only its placental tissue. It is important todemonstrate that the clinical diagnostic should always be completed by a histo-pathological diagnostic and also by thedescription of the natural history of the disease until the time of diagnostic. Material and method. The cases included inthe study (n=45 were hospitalized in ”Elena Doamna” Clinical Hospital Iaşi, in the period of time between 2008 and2013, and diagnosed with hydatidiform mole. The study was a retrospective one, case-control type. Starting from thealready diagnosed illness and following the clinical and paraclinical parameters outlined in literature, the objective of thestudy was to establish the main risk factors that trigger the molar pregnancy. Results. The epidemiological characteristicsshow the following main risk factors for a molar pregnancy: age over 30, urban area, tobacco and alcohol consumption.The mean values of βHCG decreased significantly after the hydatidiform mole was removed, from 26,624 to 9,859mUI/ml (p<0.05.Conclusions. Every woman with a history of hydatidiform mole has an increased risk of developingcarcinoma. After the complete or partial removal of the hydatidiform mole, it is necessary to monitor the values of βHCGtwice a month until they stabilize.

  10. Termite Behavior: Measuring the Postanoxic Consumption Rates of Landscape Mulches by Eastern Subterranean Termites

    Science.gov (United States)

    Collins, D. Parks

    2013-01-01

    Populations of the Eastern subterranean termite, "Reticulitermes flavipes," are widespread throughout most of the eastern United States. Subterranean termites have the ability to survive flooding conditions by lowering their metabolism. This lesson investigates the connection between the ability of termites to lower their metabolism to survive…

  11. Combined effect of microbial and chemical control agents on subterranean termites

    Science.gov (United States)

    Subterranean termites are responsible for several billion dollars in damage in the United States annually, including control and repair costs. Formosan subterranean termites (FST) cause a large proportion of this damage. The fungus Paecilomyces fumosoroseus (Pfr) has been previously shown to control...

  12. Results of the mole penetration tests in different materials

    Science.gov (United States)

    Wawrzaszek, Roman; Seweryn, Karol; Grygorczuk, Jerzy; Banaszkiewicz, Marek; Rybus, Tomasz; Wisniewski, Lukasz; Neal, Clive R.; Huang, Shaopeng

    2010-05-01

    Mole devices are low velocity, medium to high energy, self-driven penetrators, designed as a carrier of different sensors for in situ investigations of subsurface layers of planetary bodies. The maximum insertion depth of such devices is limited by energy of single mole's stroke and soil resistance for the dynamic penetration. A mole penetrator ‘KRET' has been designed, developed, and successfully tested at Space Research Centre PAS in Poland. The principle of operation of the mole bases on the interaction between three masses: the cylindrical casing, the hammer, and the rest of the mass, acting as a support mass. This approach takes advantage of the MUPUS penetrator (a payload of Philae lander on Rosetta mission) insertion tests knowledge. Main parameters of the mole KRET are listed below: - outer diameter: 20.4mm, - length: 330mm, - total mass: 488g, - energy of the driving spring: 2.2J, - average power consumption: 0.28W, - average insertion progress/stroke: 8.5mm, The present works of Space Research Center PAS team are focused on three different activities. First one includes investigations of the mole penetration effectiveness in the lunar analogues (supported by ESA PECS project). Second activity, supported by Polish national fund, is connected with numerical calculation of the heat flow investigations and designing and developing the Heat Flow Probe Hardware Component (HPHC) for L-GIP NASA project. It's worth noting that L-GIP project refers to ILN activity. Last activity focuses on preparing the second version of the mole ready to work in low thermal and pressure conditions. Progress of a mole penetrator in granular medium depends on the mechanical properties of this medium. The mole penetrator ‘KRET' was tested in different materials: dry quartz sand (0.3 - 0.8 grain size), wet quartz sand, wheat flour and lunar regolith mechanical simulant - Chemically Enhanced OB-1 (CHENOBI). Wheat flour was selected due to its high cohesion rate and small grain size

  13. Association between Breus' mole and partial hydatidiform mole: chance or can hydropic villi precipitate placental massive subchorionic thrombosis?

    Science.gov (United States)

    Kim, Dae Tong; Riddell, D Christie; Welch, J Philip; Scott, Heather; Fraser, Robert B; Wright, James R

    2002-01-01

    Breus' mole (massive subchorionic hematoma) is a rare entity most often found in the placentae of macerated stillborn fetuses. Previously considered to represent a postmortem event, recent evidence suggests that it occurs prior to fetal demise. A 23-week gestation male neonate was delivered of a 23-year-old gravida 3, para 2 woman and survived for 49 min. An autopsy with chromosomal studies resulted in a diagnosis of triploidy. Placental examination showed the presence of both Breus' mole and also partial hydatidiform mole. DNA samples extracted from portions of the fresh hematoma and from the fetal spleen were compared using molecular techniques. PCR analysis showed the presence of Y chromosome specific DNA in the placental clot, but a semiquantitative Southern blot demonstrated that roughly 85% of the clot DNA was of maternal origin. These findings suggest that Breus' mole represents primarily maternal thrombosis rather than fetal hemorrhage. We hypothesize that the partial mole could have contributed to the formation of the Breus' mole as some of the hydropic villi may have focally obstructed the maternal venous return from the intervillus space causing sluggish flow and promoting thrombosis. A review of the literature on Breus' mole shows that the majority of reported cases have not included cytogenetic findings. However, several authors have reported an association with triploidy and other chromosomal anomalies characterized by scattered placental hydropic villi. Thus, we suggest that obstruction of maternal venous return by hydropic villi may have played a contributory role in some of these other reported cases. PMID:12396900

  14. Chromosomal evolution in rodents: the case of mole rats

    Czech Academy of Sciences Publication Activity Database

    Zima, Jan; Arslan, A.

    Lisbon: -, 2014. s. 44. [Rodens et Spatium /14./. 28.07.2014-02.08.2014, Lisbon] Institutional support: RVO:68081766 Keywords : mole rats * phylogeny Subject RIV: EG - Zoology http://rslisbon2014.wix.com/conference

  15. Manganese oxides as biominerals in a granitic subterranean environment

    OpenAIRE

    Miller, A.; Dionísio, A.; Braga, M. A. Sequeira; Afonso, M. J.; Jurado, V.; Fernandez-Cortes, A.; Cuezva, S.; S. Sanchez-Moral; Saiz-Jimenez, C.; Chaminé, H.

    2011-01-01

    Black coatings were detected on granite surfaces in groundwater catch work tunnels from Porto city (NW Portugal). XRD, FTIR, Micro-Raman, ICP-MS, TEM-EDS, SEM-EDS and SEM-FIB were the analytical procedures carried out to investigate the origin of the black coatings. In this subterranean environment, the enrichment in metals and other trace elements, such as Mn and Fe, and clay minerals characterize the black microbial mats, mainly composed of Mn/Fe-oxidising bacteria. Fundação para a Ciênc...

  16. Anatomy of mole external genitalia: Setting the record straight.

    Science.gov (United States)

    Sinclair, Adriane Watkins; Glickman, Stephen E; Baskin, Laurence; Cunha, Gerald R

    2016-03-01

    Anatomy of male and female external genitalia of adult mice (Mus musculus) and broad-footed moles (Scapanus latimanus) was re-examined to provide more meaningful anatomical terminology. In the past the perineal appendage of male broad-footed moles has been called the penis, while the female perineal appendage has been given several terms (e.g. clitoris, penile clitoris, peniform clitoris and others). Histological examination demonstrates that perineal appendages of male and female broad-footed moles are the prepuce, which in both sexes are covered externally with a hair-bearing epidermis and lacks erectile bodies. The inner preputial epithelium is non-hair-bearing and defines the preputial space in both sexes. The penis of broad-footed moles lies deep within the preputial space, is an "internal organ" in the resting state and contains the penile urethra, os penis, and erectile bodies. The clitoris of broad-footed moles is defined by a U-shaped clitoral epithelial lamina. Residing within clitoral stroma encompassed by the clitoral epithelial lamina is the corpus cavernosum, blood-filled spaces and the urethra. External genitalia of male and female mice are anatomically similar to that of broad-footed moles with the exception that in female mice the clitoris contains a small os clitoridis and lacks defined erectile bodies, while male mice have an os penis and a prominent distal cartilaginous structure within the male urogenital mating protuberance (MUMP). Clitori of female broad-footed moles lack an os clitoridis but contain defined erectile bodies, while male moles have an os penis similar to the mouse but lack the distal cartilaginous structure. PMID:26694958

  17. Resource competition between two fungal parasites in subterranean termites

    Science.gov (United States)

    Chouvenc, Thomas; Efstathion, Caroline A.; Elliott, Monica L.; Su, Nan-Yao

    2012-11-01

    Subterranean termites live in large groups in underground nests where the pathogenic pressure of the soil environment has led to the evolution of a complex interaction among individual and social immune mechanisms in the colonies. However, groups of termites under stress can show increased susceptibility to opportunistic parasites. In this study, an isolate of Aspergillus nomius Kurtzman, Horn & Hessltine was obtained from a collapsed termite laboratory colony. We determined that it was primarily a saprophyte and, secondarily, a facultative parasite if the termite immunity is undergoing a form of stress. This was determined by stressing individuals of the Formosan subterranean termite Coptotermes formosanus Shiraki via a co-exposure to the virulent fungal parasite Metarhizium anisopliae (Metch.) Sorokin. We also examined the dynamics of a mixed infection of A. nomius and M. anisopliae in a single termite host. The virulent parasite M. anisopliae debilitated the termite immune system, but the facultative, fast growing parasite A. nomius dominated the mixed infection process. The resource utilization strategy of A. nomius during the infection resulted in successful conidia production, while the chance for M. anisopliae to complete its life cycle was reduced. Our results also suggest that the occurrence of opportunistic parasites such as A. nomius in collapsing termite laboratory colonies is the consequence of a previous stress, not the cause of the stress.

  18. When subterranean termites challenge the rules of fungal epizootics.

    Directory of Open Access Journals (Sweden)

    Thomas Chouvenc

    Full Text Available Over the past 50 years, repeated attempts have been made to develop biological control technologies for use against economically important species of subterranean termites, focusing primarily on the use of the entomopathogenic fungus Metarhizium anisopliae. However, no successful field implementation of biological control has been reported. Most previous work has been conducted under the assumption that environmental conditions within termite nests would favor the growth and dispersion of entomopathogenic agents, resulting in an epizootic. Epizootics rely on the ability of the pathogenic microorganism to self-replicate and disperse among the host population. However, our study shows that due to multilevel disease resistance mechanisms, the incidence of an epizootic within a group of termites is unlikely. By exposing groups of 50 termites in planar arenas containing sand particles treated with a range of densities of an entomopathogenic fungus, we were able to quantify behavioral patterns as a function of the death ratios resulting from the fungal exposure. The inability of the fungal pathogen M. anisopliae to complete its life cycle within a Coptotermes formosanus (Isoptera: Rhinotermitidae group was mainly the result of cannibalism and the burial behavior of the nest mates, even when termite mortality reached up to 75%. Because a subterranean termite colony, as a superorganism, can prevent epizootics of M. anisopliae, the traditional concepts of epizootiology may not apply to this social insect when exposed to fungal pathogens, or other pathogen for which termites have evolved behavioral and physiological means of disrupting their life cycle.

  19. Genetic variants of Cao Bang hantavirus in the Chinese mole shrew (Anourosorex squamipes) and Taiwanese mole shrew (Anourosorex yamashinai).

    Science.gov (United States)

    Gu, Se Hun; Arai, Satoru; Yu, Hon-Tsen; Lim, Burton K; Kang, Hae Ji; Yanagihara, Richard

    2016-06-01

    To determine the genetic diversity and geographic distribution of Cao Bang virus (CBNV) and to ascertain the existence of CBNV-related hantaviruses, natural history collections of archival tissues from Chinese mole shrews (Anourosorex squamipes) and Taiwanese mole shrews (Anourosorex yamashinai), captured in Guizho Province, People's Republic of China, and in Nantou County, Taiwan, in 2006 and 1989, respectively, were analyzed for hantavirus RNA by RT-PCR. Pair-wise alignment and comparison of the S-, M- and L-segment sequences indicated CBNV in two of five Chinese mole shrews and a previously unrecognized hantavirus, named Xinyi virus (XYIV), in seven of 15 Taiwanese mole shrews. XYIV was closely related to CBNV in Vietnam and China, as well as to Lianghe virus (LHEV), recently reported as a distinct hantavirus species in Chinese mole shrews from Yunnan Province in China. Phylogenetic analyses, using maximum-likelihood and Bayesian methods, showed that XYIV shared a common ancestry with CBNV and LHEV, in keeping with the evolutionary relationship between Anourosorex mole shrews. Until such time that tissue culture isolates of CBNV, LHEV and XYIV can be fully analyzed, XYIV and LHEV should be regarded as genetic variants, or genotypes, of CBNV. PMID:26921799

  20. Ultrasonographic findings of Myoma, H-mole and Missed abortion

    International Nuclear Information System (INIS)

    Ultrasonography is very important in the diagnosis of various kinds of diseases in Obsterics and Gynecology. It has high diagnostic accuracy in the diagnosis of pelvic masses and widely used for the detection of normal orpathologic pregnancy. But still it is difficult to differentiate degenerated myoma, H-mole and missed abortion by ultrasonography. So the authors analyzed the ultrasonographic findings of 81 patients with myoma(29 cases), H-mole(23 cases), and missed abortion(29 cases) and the results are as follows; 1. Diagnostic accuracy was 8.6% in myoma, 87% in H-mole and 89% in missed abortion. 2. The most typical ultrasonographic finding of myoma was obulated mass contour with nonhomogenous internal echo. 3. The most characteristic finding of H-mole was fine vesicular pattern internal echo with globular enlargement of uterus. 4. The most frequent finding of missed abortion was deformed gestational sac with or without remained fetal echo. 5. Clinical correlation was very important for accurate diagnosis, especially when differential diagnosis was very difficult between myoma with marked cystic degeneration, missed abortion with large distorted gestational sac and H-mole with severe degeneration

  1. Epidemiological Factors and Pathomorphologic Characteristics of Hydatidiform Mole

    Directory of Open Access Journals (Sweden)

    Lejla Muminhodžić

    2013-09-01

    Full Text Available Introduction: Hydatidiform mole is a gestational trophoblastic disease characterized by a range of disorders of abnormal trophoblastic proliferation.Methods: This was a retrospective study of 70 singletone pregnancies until the 12th week of gestational age diagnosed with hydatidiform mole or spontaneously aborted physiological pregnancy. The pregnantwomen had almost similar demographic features and were divided into two groups. 35 pregnant women with a molar pregnancy were included in the study group; while 35 pregnant women with physiologicalpregnancy spontaneously aborted were included in the control group. Analyzed parameters included a pregnant woman’s age, blood type, parity and previous pregnancies (course and outcomes.Results: In the study group 11.43% of cases had hydatidiform mola during previous pregnancies as well as the advanced average gestational age of an ongoing pregnancy (9.63±1.83 in contrast to 8.25±2.03in the control group. The pregnant women with the hydatidiform mole were reported to have statistically significantly greater number of irregular villous borders (71.43%; slightly enlarged villi (54.29%; moderatedpresence of cisterns (65.71% as well as mild avascularisation of villi (57.14%.Conclusion: It was concluded that a previous molar pregnancy represents the highest risk for hydtidiforme mole and the pathomorphologic analysis of vilous changes can be a reliable parameter for establishingproper diagnosis of partial hydatidiform mole.

  2. How attractive is the girl next door? An assessment of spatial mate acquisition and paternity in the solitary Cape dune mole-rat, Bathyergus suillus.

    Directory of Open Access Journals (Sweden)

    Timothy C Bray

    Full Text Available Behavioural observations of reproduction and mate choice in wild fossorial rodents are extremely limited and consequently indirect methods are typically used to infer mating strategies. We use a combination of morphological, reproductive, spatial, and genetic data to investigate the reproductive strategy of a solitary endemic species, the Cape dune mole-rat Bathyergus suillus. These data provide the first account on the population dynamics of this species. Marked sexual dimorphism was apparent with males being both significantly larger and heavier than females. Of all females sampled 36% had previously reproduced and 12% were pregnant at the time of capture. Post-partum sex ratio was found to be significantly skewed in favour of females. The paternity of fifteen litters (n = 37 was calculated, with sires assigned to progeny using both categorical and full probability methods, and including a distance function. The maximum distance between progeny and a putative sire was determined as 2149 m with males moving between sub-populations. We suggest that above-ground movement should not be ignored in the consideration of mate acquisition behaviour of subterranean mammals. Estimated levels of multiple paternity were shown to be potentially as high as 26%, as determined using sibship and sire assignment methods. Such high levels of multiple paternity have not been found in other solitary mole-rat species. The data therefore suggest polyandry with no evidence as yet for polygyny.

  3. Metadata Objects for Linking the Environmental Sciences (MOLES)

    Science.gov (United States)

    Lawrence, B.; Cox, S.; Ventouras, S.

    2009-04-01

    MOLES is an information model that provides a framework to support interdisciplinary contextual metadata describing instruments, observation platforms, activities, calibrations and other aspects of the environment associated with observations and simulations. MOLES has been designed as a bridge between discovery metadata - the conventional stuff of catalogues - and the sort of metadata which scientists traditionally store alongside data within files (and more rarely, databases) - "header files" and the like. MOLES can also be thought of as both a metadata structure in it's own right, and a framework for describing and recording the relationships between aspects of the context described in other more metadata formats (such as SensorML and the upcoming Metafor Common Information Model). MOLES was originally conceived of during the first NERC DataGrid project, in 2002, and is now at V3 in 2009. V3 differs from previous versions in many significant ways: 1) it has been designed in ISO 19103 compliant UML, and an XML schema implementation is delivered via an automated implementation of the ISO19118/19136 model driven architecture. 2) it is designed to operate in Web2.0 environment with both an atom serialisation and an OGC Web Feature Service (WFS) friendly XML serialisation. 3) it leverages the OGC observations and measurements specification, complements a range of GML application schema (in particular GeoSciML and CSML), and supports export of a subset of information in ISO 19115/19139 compliance. A software implementation exploiting MOLES V3 is under development. This will be seeded with hundreds of enties available from the MOLES V2 service currently deployed in the STFC Centre for Environmental Data Archival.

  4. Energy Efficient Networks for Monitoring Water Quality in Subterranean Rivers

    Directory of Open Access Journals (Sweden)

    Fei Ge

    2016-05-01

    Full Text Available The fresh water in rivers beneath the Earth’s surface is as significant to humans as that on the surface. However, the water quality is difficult to monitor due to its unapproachable nature. In this work, we consider building networks to monitor water quality in subterranean rivers. The network node is designed to have limited functions of floating and staying in these rivers when necessary. We provide the necessary conditions to set up such networks and a topology building method, as well as the communication process between nodes. Furthermore, we provide every an node’s energy consumption model in the network building stage, the data acquiring and transmission stage. The numerical results show that the energy consumption in every node is different, and the node number should be moderate to ensure energy efficiency.

  5. From Subterranean to Suburban: The Landscapes of Gay Outlaw Writing

    Directory of Open Access Journals (Sweden)

    Martin Dines

    2007-12-01

    Full Text Available The landscapes of sexually dissident American writing have long been conceived as entirely urban. The work of John Rechy, for instance, is always situated in the nocturnal, subterranean shadows of urban public space. The seclusion of these so-called “outlaw territories,” combined with their propinquity to mainstream society, creates an environment of near-total sexual freedom, but also a site which supposedly has the potential to disturb the city’s conventional population. However, the altogether animalistic territoriality of Rechy’s outlaw landscapes suggests instead the naturalness and timelessness of outlawry and the inevitability of conflict, rather than the possibility of change. Dennis Cooper has similarly been celebrated as an “outlaw writer”, yet much of his work is located in what amounts to the most conventional American landscape conceivable: suburbia.

  6. Diverse sulfur metabolisms from two subterranean sulfidic spring systems.

    Science.gov (United States)

    Rossmassler, Karen; Hanson, Thomas E; Campbell, Barbara J

    2016-08-01

    In sulfidic environments, microbes oxidize reduced sulfur compounds via several pathways. We used metagenomics to investigate sulfur metabolic pathways from microbial mat communities in two subterranean sulfidic streams in Lower Kane Cave, WY, USA and from Glenwood Hot Springs, CO, USA. Both unassembled and targeted recA gene assembly analyses revealed that these streams were dominated by Epsilonproteobacteria and Gammaproteobacteria, including groups related to Sulfurovum, Sulfurospirillum, Thiothrix and an epsilonproteobacterial group with no close cultured relatives. Genes encoding sulfide:quinone oxidoreductase (SQR) were abundant at all sites, but the specific SQR type and the taxonomic affiliation of each type differed between sites. The abundance of thiosulfate oxidation pathway genes (Sox) was not consistent between sites, although overall they were less abundant than SQR genes. Furthermore, the Sox pathway appeared to be incomplete in all samples. This work reveals both variations in sulfur metabolism within and between taxonomic groups found in these systems, and the presence of novel epsilonproteobacterial groups. PMID:27324397

  7. A history of mole crickets (Orthoptera: Gryllotalpidae) in Puerto Rico

    OpenAIRE

    Frank, J. Howard

    2009-01-01

    Published claims in 1887-1903 that the mole cricket Neocurtilla hexadactyla (Perty) occurs in Puerto Rico all seem to be derived from a misidentification made by Agustín Stahl, a medical practitioner and collector of natural history objects, published in 1882. That species does not seem now to occur in Puerto Rico and almost certainly never did. However, the opportunity still exists for it to colonize by wind-assisted flight from islands to the southeast just as we believe did the mole cricke...

  8. Presence of Nitrogen Fixing Klebsiella pneumoniae in the gut of the Formosan Subterranean Termite (Coptotermes formosanus)

    Science.gov (United States)

    A gram-negative facultative anaerobic enteric bacterium, Klebsiella pneumoniae was isolated from the hindgut of the Formosan subterranean termite (FST). It was characterized using, Fatty acid methyl ester (FAME) analysis, BIOLOG assay, sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-...

  9. Does subterranean flow initiate mud banks off the southwest coast of India?

    Digital Repository Service at National Institute of Oceanography (India)

    Balachandran, K.K.

    plausible mechanism to initiate the mud banks. The subterranean flow is believed to be coupled with activated trending faults and originate from the adjacent watershed (Vembanad Lake) separated from the sea by a narrow strip of land where submerged porous...

  10. Beat Subterranean: Tactics of Assemblage and Worldmaking in Beat Generation Writing

    OpenAIRE

    Fazzino, Jimmy Michael

    2012-01-01

    My dissertation argues that the core beat trope of the subterranean can be developed as a productive means of literary analysis. I show that beat writers conceive of themselves and their work as existing within vast "underground" networks of radical and avant-garde art and literature, and by locating the beats within such assemblages, the subterranean offers, above all, a model for reconceptualizing beat geography. While the Beat Generation has been regarded as quintessentially American, beat...

  11. Comparative transcriptome analysis of aerial and subterranean pods development provides insights into seed abortion in peanut

    OpenAIRE

    Wei ZHU; Chen, Xiaoping; Li, Haifen; Zhu, Fanghe; Hong, Yanbin; Rajeev K. Varshney; Liang, Xuanqiang

    2014-01-01

    The peanut is a special plant for its aerial flowering but subterranean fructification. The failure of peg penetration into the soil leads to form aerial pod and finally seed abortion. However, the mechanism of seed abortion during aerial pod development remains obscure. Here, a comparative transcriptome analysis between aerial and subterranean pods at different developmental stages was produced using a customized NimbleGen microarray representing 36,158 unigenes. By comparing 4 consecutive t...

  12. The controversy about of the mole concept and related quantities

    International Nuclear Information System (INIS)

    In this paper a display is made of the controversy about of the mole concept and related quantities (amount of substance, Avogadro's number, Avogadro's constant and molar quantities). A review of the conceptual errors which appear frequently in the textbooks of Chemistry has been made. (Author)

  13. The mole, amount of substance and primary methods

    Science.gov (United States)

    Milton, Martin J. T.

    2013-04-01

    This paper is an introduction to the principles developed for the application of metrology to the field of chemistry and particularly to analytical chemistry. It starts with a discussion of the mole, the base unit of the SI that is most relevant to analytical chemistry. The mole has become the subject of particular discussion recently, since the publication of proposals to re-define it along with three other base units of the SI. This discussion has also generated interest in the origin of the term ‘amount of substance’ used as the quantity for which the mole is the unit. This paper reviews the origin of this term and explains why it is not sufficient to replace it with an alternative such as a ‘number of entities’. The paper concludes with some discussion of how the mole is realized through the use of primary methods of measurement. This paper is based on a lecture given at the International School of Physics ‘Enrico Fermi’, Course CLXXXV: Metrology and Physical Constants,held in Varenna on 17-27 July 2012. It will also be published in the proceedings of the school, edited by E Bava, M Kühne and A M Rossi (IOS Press, Amsterdam and SIF, Bologna).

  14. Linewidth Narrowing and Intensity Enhancement of Wavelength Tunable MOLEDs

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Microcavity structure consisting of distributed Bragg reflector and metal aluminum mirror is designed. Using tris (8-hydroxyquinoline) aluminum as electron-transport layer and emissive layer, and N, N′-bis (3-methylphenyl)-N, N′-diphenylbenzidine as a hole-transport layer, microcavity organic light-emitting diodes(MOLEDs) are fabricated. Compared to the electroluminescence spectra of non-cavity OLEDs, the linewidth of the MOLEDs is compressed from 75 nm to 7 nm, and the peak intensity enhances by a factor of about 3. When the effective length of the microcavity is modified, resonance wavelength can be selectively scanned over a very wide range of wavelengths that cover almost 140 nm.

  15. Construction of Flexible Subterranean Hydraulic Barriers in Soil and Rock

    International Nuclear Information System (INIS)

    In the management of radioactive waste sites, there is sometimes a need to divert infiltration water; or contain or divert contaminated groundwater. This paper discusses several experimental techniques based on super permeating molten wax. Many of the methods are suited to form both vertical or horizontal barriers in-situ in the ground. The first method is based on thermally controlled permeation grouting between drilled holes that produces a very thick barrier in soil, rock, or even fractured rock up to 600 meters deep. The second method is a variation on jet grouting for producing a thin low cost barrier in soil. Also discussed is a technique for forming an infiltration barrier within the surface soil over an underground tank farm and a method for encapsulating a buried waste without excavation. These new methods can produce durable subterranean barriers of high integrity. These barriers are made with a special malleable wax that soaks into the soil or rock matrix. The wax is far more impermeable than clay or cement and can flex and stretch in response to soil movements. The wax contains no water and is not prone to damage from soil moisture changes. (authors)

  16. Control of subterranean termites (Isoptera: Rhinotermitidae) infesting power poles.

    Science.gov (United States)

    Horwood, Martin A; Westlake, Terry; Kathuria, Amrit

    2010-12-01

    A trial was conducted to determine the efficacy of termiticidal dusts (arsenic trioxide, triflumuron, and Metarhizium anisopliae), a timber fumigant (dazomet) and liquid termiticides (bifenthrin, chlorfenapyr, chlorpyrifos, fipronil, and imidacloprid) for controlling subterranean termites (Isoptera: Rhinotermitidae) infesting in-service power poles in New South Wales, Australia. Dusts were applied to parts of the pole where termites were present. Fumigant was inserted into holes drilled into the base of the pole. Liquid termiticides were mixed with soil around the base of the pole and injected into internal voids if present. Poles were inspected for up to 5 yr, and the time taken for reinfestation to occur was recorded. Before the start of the trial, the major Australian pole owners were surveyed to obtain an estimate of the annual national cost of termite infestation to the power supply industry. The annual costs of termite treatment and replacing damaged poles were estimated at AU$2 million and AU$13 million, respectively. Infestation rates were lower for all treatments compared with controls within the first 12 mo of the study. Dazomet, arsenic trioxide, fipronil, and chlorpyrifos were the most efficacious treatments. Efficacy was positively related to the amount of termiticide applied and negatively related to the infestation severity but was unaffected by geographical location. Survival curves were calculated of the time elapsed before the recurrence of termite infestations (survival absence of reinfestation). Survival was highest for poles treated with liquid termiticides. PMID:21309237

  17. STR DNA genotyping of hydatidiform moles in South China

    OpenAIRE

    Zheng, Xing-Zheng; Hui, Pei; Chang, Bin; Gao, Zhi-Bin; LI Yan; WU, BING-QUAN; Bo ZHANG

    2014-01-01

    Objective: To evacuate whether short-tandem-repeat (STR) DNA genotyping is effective for diagnostic measure to precisely classify hydatidiform moles. Methods: 150 cases were selected based on histologic features that were previously diagnosed or suspected molar pregnancy. All sections were stained with hematoxylin as a quality control method, and guided the microscopic dissection. DNA was extracted from dissected chorionic villi and paired maternal endometrial FFPE tissue sections. Then, STR ...

  18. Unilateral hydronephrosis caused by invasive mole: a case report

    OpenAIRE

    Zhang, Hai-Yan; Wu, Wei; Zhu, Jin

    2013-01-01

    Invasive mole belongs to gestational trophoblastic neoplasm, which is a highly curable group of pregnancy-related tumors. However, approximately 20% of gestational trophoblastic tumors will be resistant to or relapsed after initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. It is still unclear which regimens are the most effective and least toxic. Here, we report a case of unilateral hydronephrosis presenting 1 week after a hi...

  19. Correlation between infection by ophiostomatoid fungi and the presence of subterranean termites in Loblolly pine (Pinus taeda L.) roots

    Science.gov (United States)

    Observations of subterranean termites feeding in pine sapwood containing ophiostomatoid fungi prompted a study to investigate the effect of infection by Leptographium fungi on the probability of encountering subterranean termites in loblolly pine (Pinus taeda L.) roots. Root samples were collected f...

  20. Immunohistochemical characterization of the chemosensory pulmonary neuroepithelial bodies in the naked mole-rat reveals a unique adaptive phenotype.

    Directory of Open Access Journals (Sweden)

    Jie Pan

    Full Text Available The pulmonary neuroepithelial bodies (NEBs constitute polymodal airway chemosensors for monitoring and signaling ambient gas concentrations (pO2, pCO2/H+ via complex innervation to the brain stem controlling breathing. NEBs produce the bioactive amine, serotonin (5-HT, and a variety of peptides with multiple effects on lung physiology and other organ systems. NEBs in mammals appear prominent and numerous during fetal and neonatal periods, and decline in the post-natal period suggesting an important role during perinatal adaptation. The naked mole-rat (NMR, Heterocephalus glaber, has adapted to the extreme environmental conditions of living in subterranean burrows in large colonies (up to 300 colony mates. The crowded, unventilated burrows are environments of severe hypoxia and hypercapnia. However, NMRs adjust readily to above ground conditions. The chemosensory NEBs of this species were characterized and compared to those of the conventional Wistar rat (WR to identify similarities and differences that could explain the NMR's adaptability to environments. A multilabel immunohistochemical analysis combined with confocal microscopy revealed that the expression patterns of amine, peptide, neuroendocrine, innervation markers and chemosensor component proteins in NEBs of NMR were similar to that of WR. However, we found the following differences: 1 NEBs in both neonatal and adult NMR lungs were significantly larger and more numerous as compared to WR; 2 NEBs in NMR had a more variable compact cell organization and exhibited significant differences in the expression of adhesion proteins; 3 NMR NEBs showed a significantly greater ratio of 5-HT positive cells with an abundance of 5-HT; 4 NEBs in NMR expressed the proliferating cell nuclear antigen (PCNA and the neurogenic gene (MASH1 indicating active proliferation and a state of persistent differentiation. Taken together our findings suggest that NEBs in lungs of NMR are in a hyperactive, functional

  1. Burrow architecture, family composition and habitat characteristics of the largest social African mole-rat: the giant mole-rat constructs really giant burrow systems

    Czech Academy of Sciences Publication Activity Database

    Šumbera, R.; Mazoch, V.; Patzenhauerová, Hana; Lövy, M.; Šklíba, J.; Bryja, Josef; Burda, H.

    2012-01-01

    Roč. 57, č. 2 (2012), s. 121-130. ISSN 0001-7051 R&D Projects: GA AV ČR IAA601410802 Institutional research plan: CEZ:AV0Z60930519 Keywords : Fukomys mechowii * subterranean rodent * burrow system * kin structure * Bathyergidae Subject RIV: EG - Zoology Impact factor: 0.949, year: 2012

  2. Landscape Patterns of Colonization by Subterranean Termites (Isoptera: Rhinotermitidae) in Missouri Neighborhoods.

    Science.gov (United States)

    Botch, Paul S; Houseman, Richard M

    2016-04-01

    In Missouri, the relative abundances of subterranean termite species differ between undeveloped forest and urban landscapes. Reticulitermes hageni Banks occurs in greater relative proportions in forested landscapes, while Reticulitermes flavipes (Kollar) occurs in greater relative proportions in urban landscapes. Thus, subterranean termite communities appear to change at some point as landscapes are converted from undeveloped to urban. It is not known if communities change quickly in direct response to urban development, or if changes occur over time in altered urban landscapes. The purpose of this study is to examine how landscape factors are associated with subterranean termite communities and patterns of colonization as subdivisions are constructed and age. Subterranean termites were collected from 25 areas in Columbia, MO, that were classified along a gradient of urbanization to include 1) undeveloped landscapes; 2) recently disturbed transitional landscapes; 3) 10-yr-old subdivisions; and 4) 20-yr-old subdivisions. Subterranean termite communities were assessed by identifying species using polymerase chain reaction-based restriction fragment length polymorphisms. The interactions between landscape features and subterranean termites were examined using GIS software. Relative proportions of Reticulitermes spp. in communities of forest landscapes and urban areas are similar to previous reports for the state of Missouri. Termite communities appear to be locally eliminated after soils are disturbed or removed during subdivision development, although remnant colonies can persist in areas that are not disturbed. Reticulitermes flavipes appears to colonize subdivisions quickly regardless of historical or contemporary landscape; however, R. hageni colonization generally becomes more common as subdivisions age and gradually become more forested. PMID:26838347

  3. Determining different parameters of Co-60 bait as a radiotracer for three species of subterranean termites

    International Nuclear Information System (INIS)

    Laboratory studies were conducted to test the feasibility of using Cobalt-60 for tracing the nesting system of subterranean termites. Over a period of four weeks, mortality caused by feeding on bait containing Cobalt-60 (30 microcurie) did not exceed 6% in Heterotermes indicola, Microtermes unicolor or Reticulitermes. The data on radiation distribution in different body parts of H. indicola after feeding on radioactive bait showed maximum radioactivity in gut (64.63%) followed by external contamination (26.81%), appendages (5.87%) and exoskeleton (2.92%). It was concluded that Co-60 label bait could safely be used as a radiotracer to study the nesting system of subterranean termites. (author)

  4. Vision - night blindness

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003039.htm Vision - night blindness To use the sharing features on ... page, please enable JavaScript. Night blindness is poor vision at night or in dim light. Considerations Night ...

  5. Onchocerciasis (River Blindness) FAQs

    Science.gov (United States)

    ... The CDC Parasites - Onchocerciasis (also known as River Blindness) Note: Javascript is disabled or is not supported ... infected Simulium blackfly. It is also called River Blindness because the fly that transmits infection breeds in ...

  6. Leading Causes of Blindness

    Science.gov (United States)

    ... Issue Past Issues Feature: Vision Leading Causes of Blindness Past Issues / Summer 2008 Table of Contents For ... have cataracts. They are the leading cause of blindness in the world. By age 80, more than ...

  7. Gibraltar from end of Old [mistitled] Mole. circa 1880

    OpenAIRE

    Unknown

    2003-01-01

    1206 x 221 mm. A panoramic view composed of 5 joined prints, cloth-backed. The panorama shows a view looking towards the south part of the town from the New Mole. At the right of the photograph ships and hulks are moored at the dockyard with the town beyond. Among the prominent buildings identifiable are the South Barracks behind the town, the Barrack Chapel directly in front, and the Station Hospital on the skyline at the right of the picture. The panorama follows the sea wall and the R...

  8. Alpine endemic spiders shed light on the origin and evolution of subterranean species.

    Science.gov (United States)

    Mammola, Stefano; Isaia, Marco; Arnedo, Miquel A

    2015-01-01

    We designed a comparative study to unravel the phylogeography of two Alpine endemic spiders characterized by a different degree of adaptation to subterranean life: Troglohyphantes vignai (Araneae, Linyphiidae) and Pimoa rupicola (Araneae, Pimoidae), the latter showing minor adaptation to hypogean life. We sampled populations of the model species in caves and other subterranean habitats across their known geographical range in the Western Alps. By combining phylogeographic inferences and Ecological Niche Modeling techniques, we inferred the biogeographic scenario that led to the present day population structure of the two species. According to our divergent time estimates and relative uncertainties, the isolation of T. vignai and P. rupicola from their northern sister groups was tracked back to Middle-Late Miocene. Furthermore, the fingerprint left by Pleistocene glaciations on the population structure revealed by the genetic data, led to the hypothesis that a progressive adaptation to subterranean habitats occurred in T. vignai, followed by strong population isolation. On the other hand, P. rupicola underwent a remarkable genetic bottleneck during the Pleistocene glaciations, that shaped its present population structure. It seems likely that such shallow population structure is both the result of the minor degree of specialization to hypogean life and the higher dispersal ability characterizing this species. The simultaneous study of overlapping spider species showing different levels of adaptation to hypogean life, disclosed a new way to clarify patterns of biological diversification and to understand the effects of past climatic shift on the subterranean biodiversity. PMID:26734503

  9. INTERIM PROTOCOL FOR TESTING THE EFFECTS OF MICROBIAL PATHOGENS ON SUBTERRANEAN TERMITES (ISOPTERA: RHINOTERMITIDAE)

    Science.gov (United States)

    Although subterranean termites are frequent targets of pest control measures around buildings and other human constructions, they are also ubiquitous in both wooded and desert regions of North America and are likely to suffer unintended exposure to MPCA's. here are few reports of...

  10. SUBTERRANEAN TERMITES: REGULATORS OF SOIL ORGANIC MATTER IN THE CHICHUAHUAN DESERT

    Science.gov (United States)

    Soil organic matter and the abundance of subterranean termites were measured at 89 locations spaced at 30-m intervals from the bottom of the top of a small desert watershed. here was no correlation between soil organic matter content and topographic position on the watershed. nal...

  11. Functional analyses of the digestive ß-Glucosidase of Formosan Subterranean Termites (Coptotermes formosanus)

    Science.gov (United States)

    The research was to elucidate the function of the ß-glucosidase of Formosan subterranean termites in vitro and in vivo. Quantitative RT-PCR analyses indicated that the gene transcript was relatively more abundant in the foraging worker caste than in other castes and salivary glands were the major ex...

  12. Effect of catnip oil and its major components on the Formosan subterranean termites

    Science.gov (United States)

    Various semiochemical properties are key attributes of ZE (4aS, 7S, 7aR) and EZ (4aS, 7S, 7aS)-nepetalactone isomers quantitatively separated from commercially available catnip oil. When evaluated against Formosan subterranean termites, these environment friendly and commercially viable monoterpenoi...

  13. Activity of 1,4-Benzoquinones Against Formosan Subterranean Termites, Coptotermes formosanus

    Science.gov (United States)

    A large number of naturally occurring and synthetic benzoquinones were evaluated for activity against the Formosan subterranean termite, Coptotermes formosanus, with potential use in termite control. Among these bioactive naturally occurring benzoquinones are 2-methyl-5-isopropyl-1,4-benzoquinone, ...

  14. Effect of Flooding on the Survival of Formosan Subterranean Termites (Isoptera: Rhinotermitidae) in Laboratory Tests

    Science.gov (United States)

    Underground monitoring stations were active with Formosan subterranean termites, Coptotermes formosanus Shiraki, less than a month after the flood waters receded from an urban park, City Park, New Orleans, Louisiana. This study examines whether the presence of galleries in soil or wood increases su...

  15. Tunneling behavior of the formosan subterranean termite (isoptera: rhinotermitadae) in dry soil

    Science.gov (United States)

    This study examines the effect of dry soil on tunnel construction by the Formosan subterranean termite, Cptotermes formosanus. Termites did not construct tunnels in dry soil in any of the treatments. Termites only constructed tunnels in moist areas in treatments where the soil was partially moistene...

  16. Temporarily plugging a subterranean reservoir with a self-foaming aqueous solution

    Energy Technology Data Exchange (ETDEWEB)

    Berkshire, D.C.; Lybarger, J.H.; Reisberg, J.; Richardson, E.A.; Scheuerman, R.F.

    1980-11-11

    Portions of a subterranean reservoir are temporarily plugged by injecting an aqueous liquid solution which contains nitrogen gasgenerating reactants, a foaming surfactant and a pH controlling system arranged so that the solution remains relatively unreactive within the well but forms a relatively immobile foam within the pores or other openings within the reservoir formation.

  17. The change in students' understanding of the mole concept in introductory college chemistry

    Science.gov (United States)

    Smith, Shane Harvie

    This study investigated the difference between the students' understanding of the mole concept in chemistry at the beginning and at the end of the first semester of introductory chemistry courses. The study also identified the relationship between the criterion variable understanding of the mole concept in chemistry and the independent variables of cognitive level, type of introductory college chemistry class, and the number of lectures spent teaching the mole concept. In addition, this study examined (a) the students' misconceptions and (b) the aspects of the traditional teaching methods used in the introductory college chemistry courses that helped the students' understanding of the mole concept. This study was conducted using 180 volunteer students in their first semester of an introductory college chemistry course. These students were given a pretest instrument called the Mole Concepts Examination (MCE) to measure their understanding of the mole concept, the Group Assessment of Logical Thinking (GALT) to measure the students' cognitive level of logical thinking, and a posttest of the MCE to measure the students' understanding of the mole concept at the end of the semester. In addition, an interview was given to a selected group of 18 students to find out if the students remember the teaching techniques used to help them understand the mole concept and to determine some of the misconceptions that the students retained at the end of the semester. Results indicated a statistically significant relationship between students' understanding of the mole concept and their cognitive level. There was no significant relationship between students' understanding of the mole concept and the type of class, or the number of lectures spent teaching the mole concept. Qualitative results indicated that students were able to explain their answers to the posttest questions; students were able to identify some instructional techniques that helped them to understand the mole concept

  18. Does the morphology of the ear of the Chinese bamboo rat (Rhizomys sinensis) show "Subterranean" characteristics?

    Science.gov (United States)

    Pleštilová, Lucie; Hrouzková, Ema; Burda, Hynek; Šumbera, Radim

    2016-05-01

    In spite of the growing interest in rodents with subterranean activity in general and the spalacids (Spalacidae) in particular, little is known about the biology of most members of this clade, such as the Chinese bamboo rat (Rhizomys sinensis). Here, we analyzed the ear morphology of R. sinensis with respect to hearing specialization for subterranean or aboveground modes of communication. It is well-known that ecology and style of life of a particular species can be reflected in morphology of its ear, its hearing and vocalization, so we expect that such information could provide us insight into its style of life and its sensory environment. The ratio between the eardrum and stapedial footplate areas, which influences the efficiency of middle ear sound transmission, suggests low hearing sensitivity, as is typical for subterranean species. The cochlea had 3.25 coils and resembled species with good low frequency hearing typical for subterranean mammals. The length of the basilar membrane was 18.9 ± 0.8 mm and its width slowly increased towards the cochlear apex from 60 to 85 μm. The mean density of outer hair cells was 344 ± 22 and of inner hair cells 114 ± 7.3 per 1 mm length of the organ of Corti, and increased apically. These values (except for relatively low hair cell density) usually characterize ears specialized for low frequency hearing. There was no evidence for an acoustic fovea. Apart of low hair cell density which is common in aboveground animals, this species has also relatively large auricles, suggesting the importance of sound localization during surface activity. The ear of the Chinese bamboo rat thus contains features typical for both aboveground and subterranean mammals and suggests that this spalacid has fossorial habits combined with regular aboveground activity. PMID:26880690

  19. Genetic and epigenetic analysis of recurrent hydatidiform mole.

    Science.gov (United States)

    Hayward, Bruce E; De Vos, Michel; Talati, Nargese; Abdollahi, M Reza; Taylor, Graham R; Meyer, Esther; Williams, Denise; Maher, Eamonn R; Setna, Faridon; Nazir, Kausar; Hussaini, Shahnaz; Jafri, Hussain; Rashid, Yasmin; Sheridan, Eamonn; Bonthron, David T

    2009-05-01

    Familial biparental hydatidiform mole (FBHM) is a maternal-effect autosomal recessive disorder in which recurrent pregnancy failure with molar degeneration occurs. The phenotype mimics molar pregnancy due to androgenesis, despite the normal genetic makeup of the conceptus. FBHM appears to result from a failure to establish correct maternal epigenetic identity at imprinted loci during oogenesis. Several women affected with FBHM have previously been shown to have biallelic mutations in the NLRP7 gene (NALP7). Here, we present the results of epigenetic and mutational analysis on FBHM patients from 11 families, 10 of them novel. We demonstrate a methylation defect at imprinted loci in tissue from four new FBHM cases. Biallelic NLRP7 mutations, including eight previously undescribed mutations, were found in all but one family. These results indicate for the first time that maternal imprints at some loci may be correctly specified in FBHM conceptions, since differential methylation of SGCE/PEG10 was preserved in all four cases. PMID:19309689

  20. New sytematic insights about Plio-Pleistocene moles from Poland

    Directory of Open Access Journals (Sweden)

    Gabriele Sansalone

    2016-02-01

    Full Text Available The generic attribution of the Plio-Pleistocene Polish moles ?Neurotrichus polonicus and ?Neurotrichus skoczeni has been questioned several times in the past. The fossil material belonging to ?Neurotrichus polonicus and ?Neurotrichus skoczeni is re-evaluated here and a new diagnosis is provided on the basis of qualitative considerations. In addition, a Geometric Morphometric analysis of the humerus has been performed including both extant and extinct Neurotrichini and Urotrichini taxa for comparison. Our results proved the unique morphology of the Polish material suggesting a distinct taxonomic state. The morphological variations evidenced by the humeral shape analysis agree with the observed qualitative differences and support a new generic allocation. The new genus Rzebikia gen. nov. is proposed for all the material previoulsly ascribed to ?Neurotrichus polonicus and ?Neurotrichus skoczeni.

  1. Postictal blindness in adults.

    OpenAIRE

    Sadeh, M; Goldhammer, Y.; Kuritsky, A

    1983-01-01

    Cortical blindness following grand mal seizures occurred in five adult patients. The causes of seizures included idiopathic epilepsy, vascular accident, brain cyst, acute encephalitis and chronic encephalitis. Blindness was permanent in one patients, but the others recovered within several days. Since most of the patients were either unaware of or denied their blindness, it is possible that this event often goes unrecognised. Cerebral hypoxia is considered the most likely mechanism.

  2. Hypersensitivity to contact inhibition provides a clue to cancer resistance of naked mole-rat

    OpenAIRE

    Seluanov, Andrei; Hine, Christopher; Azpurua, Jorge; Feigenson, Marina; Bozzella, Michael; Mao, Zhiyong; Catania, Kenneth C.; Gorbunova, Vera

    2009-01-01

    The naked mole-rat is the longest living rodent with a maximum lifespan exceeding 28 years. In addition to its longevity, naked mole-rats have an extraordinary resistance to cancer as tumors have never been observed in these rodents. Furthermore, we show that a combination of activated Ras and SV40 LT fails to induce robust anchorage-independent growth in naked mole-rat cells, while it readily transforms mouse fibroblasts. The mechanisms responsible for the cancer resistance of naked mole-rat...

  3. Effects of Flooding on Field Populations of Formosan Subterranean Termites, Coptotermes formosanus Shiraki (Isoptera: Rhinotermitidae), in New Orleans, LA

    Science.gov (United States)

    Periodic sampling of independent monitors, initially active with the Formosan subterranean termite, Coptotermes formosanus Shiraki, was conducted to evaluate the effects of long term flooding on termite populations. Monitors were located adjacent to buildings and in urban forests. Significant popu...

  4. Prevent Blindness America

    Science.gov (United States)

    Advocacy Our Partners Prevent Blindness in your State Search Site Your Sight Your Sight What's Your Risk of a Vision Problem? Signs of Eye Problems ... School Your Child's Glasses Wearing Contact Lenses Prevent Blindness and Children's Vision Protecting Your Child's Eyes from ...

  5. Blindness%失明

    Institute of Scientific and Technical Information of China (English)

    李同良

    2009-01-01

    @@ There was a blind girl who hated herself because she was blind. She hated everyone,except her loving boyfriend who was always there for her. She told her boyfriend, "If I could only see the World, I will marry you."

  6. Facts About Color Blindness

    Science.gov (United States)

    ... quickly diagnose specific types of color blindness. The Ishihara Color Test is the most common test for red-green ... red-green color blindness. The newer Cambridge Color Test uses a visual array similar to the Ishihara plates, except displayed on a computer monitor. The ...

  7. Blindness in Otters

    OpenAIRE

    Williams J

    1989-01-01

    In England, which has a long history of well-recorded otter hunts, there were historically no records of blind but fit otters. The author obtained records of 22 blind but otherwise fit otters observed between 1957 and 1980, but none before or since; this seems to correspond with the period of greatest otter decline.

  8. Models for the blind

    DEFF Research Database (Denmark)

    Olsén, Jan-Eric

    2014-01-01

    When displayed in museum cabinets, tactile objects that were once used in the education of blind and visually impaired people, appear to us, sighted visitors, as anything but tactile. We cannot touch them due to museum policies and we can hardly imagine what it would have been like for a blind...... person to touch them in their historical context. And yet these objects are all about touch, from the concrete act of touching something to the norms that assigned touch a specific pedagogical role in nineteenth-century blind schools. The aim of this article is twofold. First, I provide a historical...... background to the tactile objects of the blind. When did they appear as a specific category of pedagogical aid and how did they help determine the relation between blindness, vision, and touch? Second, I address the tactile objects from the point of view of empirical sources and historical evidence. Material...

  9. Change blindness images.

    Science.gov (United States)

    Ma, Li-Qian; Xu, Kun; Wong, Tien-Tsin; Jiang, Bi-Ye; Hu, Shi-Min

    2013-11-01

    Change blindness refers to human inability to recognize large visual changes between images. In this paper, we present the first computational model of change blindness to quantify the degree of blindness between an image pair. It comprises a novel context-dependent saliency model and a measure of change, the former dependent on the site of the change, and the latter describing the amount of change. This saliency model in particular addresses the influence of background complexity, which plays an important role in the phenomenon of change blindness. Using the proposed computational model, we are able to synthesize changed images with desired degrees of blindness. User studies and comparisons to state-of-the-art saliency models demonstrate the effectiveness of our model. PMID:24029902

  10. Occurrence and activity of subterranean termites in temperate forest soils: United States and Spain

    Science.gov (United States)

    Jurgensen, M.; Page-Dumroese, D.; Cerdà, A.; Forschler, B.; Trettin, C.; Cook, S.; Kard, B.

    2009-04-01

    Termites are an important component of many tropical, sub-tropical, and temperate soil invertebrate communities, and they have an impact on soil hydrological, chemical and biological processes. Termites also emit methane and could be an important factor in the production of this important atmospheric greenhouse gas. Many studies have been conducted on mound-building termites in tropical ecosystems, but much less is known on the ecology of subterranean termites in temperate soils. Most of the information about the subterranean termites is derived from work focused on protecting dwellings, which does not necessarily translate to ecosystem-level functions. We have developed an international network across diverse biomes to assess wood decomposition in forests; this presentation will summarize findings on the effects role of termites. Their occurrence is much more prevalent than commonly thought, and their role in mediating wood turnover appears to be significant.

  11. Trees as indicators of subterranean water flow from a retired radioactive waste disposal site.

    Science.gov (United States)

    Rickard, W H; Kirby, L J

    1987-02-01

    Tree sampling helped locate a subterranean flow of tritiated water from a low-level radioactive waste disposal site that had not been detected by well water monitoring alone. Deciduous trees growing in a natural forest on the hillsides downslope from the site were sampled for the presence of tritiated water in sap of maple trees and in leaf water extracted from oak and hickory trees. Elevated concentrations of 3H were detected in the leaf water extracted from several trees located 50 m downslope from the western boundary of the fenced exclusion zone. A 3-m-deep well drilled near these trees indicated that the source of tritiated water was a narrow zone of subterranean flow. PMID:3818287

  12. Trees as indicators of subterranean water flow from a retired radioactive waste disposal site

    International Nuclear Information System (INIS)

    Tree sampling helped locate a subterranean flow of tritiated water from a low-level radioactive waste disposal site that had not been detected by well water monitoring alone. Deciduous trees growing in a natural forest on the hillsides downslope from the site were sampled for the presence of tritiated water in sap of maple trees and in leaf water extracted from oak and hickory trees. Elevated concentrations of 3H were detected in the leaf water extracted from several trees located 50 m downslope from the western boundary of the fenced exclusion zone. A 3-m-deep well drilled near these trees indicated that the source of tritiated water was a narrow zone of subterranean flow

  13. Materials for the vegetative identification of segetal weeds sprouted from subterranean organs

    Directory of Open Access Journals (Sweden)

    Antal NYARADY

    1970-08-01

    Full Text Available In complement of their paper about the morphology of weed seedlings geminated from seeds (Acta Agron. acada.Sci. Hung., Tom. XVIII, 1969, pp.1-47 in this note the authors presents the results of comparative morphological studies on perennial segetal weeds sprouted from subterranean organs. The verified distinctive characteristics are included in an analitical key which allow the identification of 72 weed species (3 Pteridophytae, 17 Monocotyledoneae, 52 Dicotyledoneae recurrent on the ploughed fields in Romania.

  14. Subterranean Microhabitat Dependent Intra Versus Extracellular Enzyme Secretion Capabilities of Deinococcus radiodurans

    OpenAIRE

    Jayant Biswas; Arvind Neral; Yogita Rajput

    2015-01-01

    Deinococcus radiodurans is one of the most yet discovered extremophilic microbe, the isolation of which from the various habitats of Kotumsar cave is always a matter of enticement to discover its ecological economics. In the present work we studied the intra versus extracellular alkaline protease and glucose isomerase secretion capabilities of Deinococcus radiodurans; KCB21, KCB50, KCB93 isolated from three distinct subterranean niches of Kotumsar cave. The selected niches/zones were the entr...

  15. Strategies for monitoring and conservation of troglobitic endemic fauna in some subterranean sites od Sardinia

    OpenAIRE

    Marcia, Paolo

    2009-01-01

    From the biogeographic and biospeleological points of view, the subterranean fauna of Sardinia is one of the most interesting in the Mediterranean area: very rich in taxa, mostly endemic and highly specialised, it is apparently well known and currently investigated. Nevertheless, the amount of unexpected discoveries is still increasing every year. In the present thesis, at first, owing to the general low interest of the public for the protection of invertebrate endemic, trog...

  16. Blinded by Irrelevance: Pure Irrelevance Induced "Blindness"

    Science.gov (United States)

    Eitam, Baruch; Yeshurun, Yaffa; Hassan, Kinneret

    2013-01-01

    To what degree does our representation of the immediate world depend solely on its relevance to what we are currently doing? We examined whether relevance per se can cause "blindness," even when there is no resource limitation. In a novel paradigm, people looked at a colored circle surrounded by a differently colored ring--the task relevance of…

  17. How "Blind" Are Double-Blind Studies?

    Science.gov (United States)

    Margraf, Jurgen; And Others

    1991-01-01

    Compared alprazolam, imipramine, and placebo in the treatment of panic disorder patients (n=59) to investigate concerns about the internal validity of the double-blind design. Found that the great majority of patients and physicians were able to rate accurately whether active drug or placebo had been given and physicians could distinguish between…

  18. Ontogeny of spatial working memory in the subterranean rodent ctenomys talarum.

    Science.gov (United States)

    Schleich, Cristian E

    2010-09-01

    While several works analyzed the spatial learning and memory capacities in adults of subterranean rodents, no study was done examining the development of these cognitive processes in pups of any of those species. Therefore, the development of spatial working memory in the South American subterranean rodent Ctenomys talarum was investigated by analyzing the pups' spatial performance in a delayed alternation task. When a short delay of 1 min was interposed between runs in the Y-maze, 20-day-old pups made more errors than 40- and 60-day-old pups. When longer intervals (10 min) were elapsed between runs, younger pups made approximately twice as many errors as the ones committed by 60-day-old pups, showing the age-dependent development of spatial working memory in this species of subterranean rodent. Increased space use by C. talarum pups, caused first by the appearance of independent exploratory behavior and later by the need of leaving maternal territory and construct a new burrow system, showed some correspondence with the improvements in the pups' spatial working memory performance, suggesting for the importance of this cognitive capacity in developing pups for which spatial learning and memory constitute essential abilities for survival and fitness. PMID:20806332

  19. Evolution of subterranean diving beetles (Coleoptera: Dytiscidae: Hydroporini, Bidessini) in the arid zone of Australia.

    Science.gov (United States)

    Leys, Remko; Watts, Chris H S; Cooper, Steve J B; Humphreys, William F

    2003-12-01

    Calcrete aquifers in arid inland Australia have recently been found to contain the world's most diverse assemblage of subterranean diving beetles (Coleoptera: Dytiscidae). In this study we test whether the adaptive shift hypothesis (ASH) or the climatic relict hypothesis (CRH) is the most likely mode of evolution for the Australian subterranean diving beetles by using a phylogeny based on two sequenced fragments of mitochondrial genes (CO1 and 16S-tRNA-ND1) and linearized using a relaxed molecular clock method. Most individual calcrete aquifers contain an assemblage of diving beetle species of distantly related lineages and/or a single pair of sister species that significantly differ in size and morphology. Evolutionary transitions from surface to subterranean life took place in a relatively small time frame between nine and four million years ago. Most of the variation in divergence times of the sympatric sister species is explained by the variation in latitude of the localities, which correlates with the onset of aridity from the north to the south and with an aridity maximum in the Early Pliocene (five mya). We conclude that individual calcrete aquifers were colonized by several distantly related diving beetle lineages. Several lines of evidence from molecular clock analyses support the CRH, indicating that all evolutionary transitions took place during the Late Miocene and Early Pliocene as a result of aridification. PMID:14761060

  20. Acanthocephala Parasite (Profilicollis spp.) Loads in Correlation to Pacific Mole Crab (Emerita analoga) Size

    Science.gov (United States)

    Cheng, T.; Huang, S.; Galathe, M.; Jenkins, M.; Ramirez, A.; Crosby, L.; Barrera, J.; FitzHoward, S.

    2013-12-01

    Since 2002, San Francisco Bay students have been conducting marine ecosystem monitoring through a joint project with the Long-term Monitoring Program and Experiential Training for Students (LiMPETS), in conjunction with the Gulf of Farallones National Marine Sanctuary. Each year students collect population and demographic data on Pacific mole crabs (Emerita analoga), an indicator species that lives in the sandy beach habitat in temperate regions along the Pacific Ocean. Pacific mole crabs are filter feeding crustaceans that inhabit the intertidal swash zone and are known to be an intermediate host for parasitic ';spiny-headed' worms in the phylum Acanthocephala (Profilicollis spp.). Sampling takes place during their reproductive period, which occurs from spring to fall, and includes measuring total body length of the Pacific mole crabs and dissecting them to determine presence of Acanthocephalan parasites. We hypothesize that due to larger body mass, larger Pacific mole crabs will have a greater number of Acanthocephala parasites.We conducted several analyses using the LiMPETS long-term data. Specifically, we compared body length, crab gender, and parasite abundance from Pacific mole crabs sampled from four beaches located in the county and city of San Francisco. Our results indicated that larger Pacific mole crabs do not necessarily have more parasites, but are more likely to have at least one parasite, while female Pacific mole crabs carrying eggs, have more parasites than males or females without eggs. We also found that parasite loads per mole crab was highest in the spring. Further analysis will be conducted to determine factors affecting Pacific mole crab parasite loads. Studying Pacific mole crabs help evaluate the health of California's intertidal systems and how human activities, geologic changes, and climate changes all make huge impacts to the intertidal ecosystems.

  1. Static analysis for blinding

    DEFF Research Database (Denmark)

    Nielsen, Christoffer Rosenkilde; Nielson, Hanne Riis

    2006-01-01

    operation blinding. In this paper we study the theoretical foundations for one of the successful approaches to validating cryptographic protocols and we extend it to handle the blinding primitive. Our static analysis approach is based on Flow Logic; this gives us a clean separation between the specification...... of the analysis and its realisation in an automatic tool. We concentrate on the former in the present paper and provide the semantic foundation for our analysis of protocols using blinding - also in the presence of malicious attackers....

  2. Blind Collective Signature Protocol

    Directory of Open Access Journals (Sweden)

    Nikolay A. Moldovyan

    2011-06-01

    Full Text Available Using the digital signature (DS scheme specified by Belarusian DS standard there are designed the collective and blind collective DS protocols. Signature formation is performed simultaneously by all of the assigned signers, therefore the proposed protocols can be used also as protocols for simultaneous signing a contract. The proposed blind collective DS protocol represents a particular implementation of the blind multisignature schemes that is a novel type of the signature schemes. The proposed protocols are the first implementations of the multisignature schemes based on Belarusian signature standard.

  3. Jumping mechanisms and performance of pygmy mole crickets (Orthoptera, Tridactylidae).

    Science.gov (United States)

    Burrows, M; Picker, M D

    2010-07-15

    Pygmy mole crickets live in burrows at the edge of water and jump powerfully to avoid predators such as the larvae and adults of tiger beetles that inhabit the same microhabitat. Adults are 5-6 mm long and weigh 8 mg. The hind legs are dominated by enormous femora containing the jumping muscles and are 131% longer than the body. The ratio of leg lengths is: 1:2.1:4.5 (front:middle:hind, respectively). The hind tarsi are reduced and their role is supplanted by two pairs of tibial spurs that can rotate through 180 deg. During horizontal walking the hind legs are normally held off the ground. Jumps are propelled by extension of the hind tibiae about the femora at angular velocities of 68,000 deg s(-1) in 2.2 ms, as revealed by images captured at rates of 5000 s(-1). The two hind legs usually move together but can move asynchronously, and many jumps are propelled by just one hind leg. The take-off angle is steep and once airborne the body rotates backwards about its transverse axis (pitch) at rates of 100 Hz or higher. The take-off velocity, used to define the best jumps, can reach 5.4 m s(-1), propelling the insect to heights of 700 mm and distances of 1420 mm with an acceleration of 306 g. The head and pronotum are jerked rapidly as the body is accelerated. Jumping on average uses 116 microJ of energy, requires a power output of 50 mW and exerts a force of 20 mN. In jumps powered by one hind leg the figures are about 40% less. PMID:20581268

  4. The chromosome banding pattern in two cytotypes (2n = 36 and 38) of blind mole rats from Turkey (Mammalia: Spalaxidae)

    Czech Academy of Sciences Publication Activity Database

    Arslan, A.; Arisoy, A.; Zima, Jan

    2013-01-01

    Roč. 59, č. 2 (2013), s. 95-100. ISSN 0939-7140 Institutional support: RVO:68081766 Keywords : Nannospalax xanthodon * Ag-NOR staining * C-banding * Aydin * Manisa * western Anatolia Subject RIV: EG - Zoology Impact factor: 0.524, year: 2013

  5. A Blind Date

    Institute of Scientific and Technical Information of China (English)

    周立

    2003-01-01

    英语对话:A: Talking about girls, I still remember my first time to meet my girlfriend. Iwas so clumsy and very nervous.B: That’s the same case with me. I had the jitters at my blind date, too.A: Did you also meet your girlfriend at a blind date?B: Yeah. I was actually very shy of speaking to girls, you know?

  6. Factors affecting blind mobility

    OpenAIRE

    Clark-Carter, David

    1985-01-01

    This thesis contains a survey of the mobility problems of blind people, experimental analysis and evaluation of these problems and suggestions for ways in which the evaluation of mobility performance and the design of mobility aids may be improved. The survey revealed a low level of mobility among blind people, with no significant improvement since a comparable survey in 1967. A group of self taught cane users were identified and their mobility was shown to be poor or potentially dangero...

  7. Models for the Blind

    Directory of Open Access Journals (Sweden)

    Jan Eric Olsén

    2014-10-01

    Full Text Available When displayed in museum cabinets, tactile objects that were once used in the education of blind and visually impaired people, appear to us, sighted visitors, as anything but tactile. We cannot touch them due to museum policies and we can hardly imagine what it would have been like for a blind person to touch them in their historical context. And yet these objects are all about touch, from the concrete act of touching something to the norms that assigned touch a specific pedagogical role in nineteenth-century blind schools. The aim of this article is twofold. First, I provide a historical background to the tactile objects of the blind. When did they appear as a specific category of pedagogical aid and how did they help determine the relation between blindness, vision, and touch? Second, I address the tactile objects from the point of view of empirical sources and historical evidence. Material objects are rarely used as historical testimonies for the simple reason that they, unlike archival material, do not present historians with written documents that can be held as evidence of the past. However, as I point out, certain historical questions of which archives remain silent could be approached by other means such as the use of material objects. Rather than delivering concrete methodological suggestions, this second part reflects upon the historical use of material objects - both their possibilities and their limits - within the context of blindness.

  8. Blind Analysis in Particle Physics

    OpenAIRE

    Roodman, Aaron

    2003-01-01

    A review of the blind analysis technique, as used in particle physics measurements, is presented. The history of blind analyses in physics is briefly discussed. Next the dangers of "experimenter's bias" and the advantages of a blind analysis are described. Three distinct kinds of blind analysis in particle physics are presented in detail. Finally, the BABAR collaboration's experience with the blind analysis technique is discussed.

  9. Biodiesel From Canola Oil Using a 1:1 Mole Mixture of Methanol and Ethanol

    Science.gov (United States)

    Canola oil was transesterified using a 1:1 mole mixture of methanol and ethanol (M/E) with potassium hydroxide (KOH) catalyst. Effect of catalyst concentration (0.5 to 1.5% wt/wt), mole ratio of M/E to canola oil (3:1 to 20:1) and reaction temperature (25 to 75°C) on the percentage yield measured af...

  10. [Response Mechanism of Trace Metals in the Bishuiyan Subterranean River to the Rainfall and Their Source Analysis].

    Science.gov (United States)

    Zou, Yan-e; Jiang, Ping-ping; Zhang, Qiang; Tang, Qing-jia; Kang, Zhi-qiang; Gong, Xiao- ping; Chen, Chang-jie; Yu, Jian-guo

    2015-12-01

    High-frequency sampling was conducted at the outlet of Guangxi Bishuiyan karst subterranean river using an automatic sampler during the rainfall events. The hydrochemical drymanic variation characteristics of trace metals (Cu, Pb, Zn, Cd) at the outlet of Guangxi Bishuiyan karst subterranean river were analyzed, and the sources of the trace metals in the subterranean river as well as their response to rainfall were explored. The results showed that the rainfall provoked a sharp decrease in the major elements (Ca²⁺, Mg²⁺, HCO₃⁻, etc.) due to dilution and precipitation, while it also caused an increase in the concentrations of dissolved metals including Al, Mn, Cu, Zn and Cd, due to water-rock reaction, sediment remobilization, and soil erosion. The water-rock reaction was more sensitive to rainfall than the others, while the sediment remobilization and soil erosion took the main responsibility for the chemical change of the heavy metals. The curves of the heavy metal concentrations presented multiple peaks, of which the maximum was reached at 9 hours later after the largest precipitation. Different metal sources and the double-inlet structure of the subterranean river were supposed to be the reasons for the formation of multiple peaks. During the monitoring period, the average speed of the solute in the river reached about 0.47 km · h⁻¹, indicating fast migration of the pollutants. Therefore, monitoring the chemical dynamics of the karst subterranean river, mastering the sources and migration characteristics of trace metal components have great significance for the subterranean river environment pollution treatment. PMID:27011981

  11. Non-conservative behavior of fluorescent dissolved organic matter (FDOM) within a subterranean estuary

    Science.gov (United States)

    Suryaputra, I. G. N. A.; Santos, I. R.; Huettel, M.; Burnett, W. C.; Dittmar, T.

    2015-11-01

    The role of submarine groundwater discharge (SGD) in releasing fluorescent dissolved organic matter (FDOM) to the coastal ocean and the possibility of using FDOM as a proxy for dissolved organic carbon (DOC) was investigated in a subterranean estuary in the northeastern Gulf of Mexico (Turkey Point, Florida). FDOM was continuously monitored for three weeks in shallow beach groundwater and in the adjacent coastal ocean. Radon (222Rn) was used as a natural groundwater tracer. FDOM and DOC correlated in groundwater and seawater samples, implying that FDOM may be a proxy of DOC in waters influenced by SGD. A mixing model using salinity as a seawater tracer revealed FDOM production in the high salinity region of the subterranean estuary. This production was probably a result of infiltration and transformation of labile marine organic matter in the beach sediments. The non-conservative FDOM behavior in this subterranean estuary differs from most surface estuaries where FDOM typically behaves conservatively. At the study site, fresh and saline SGD delivered about 1800 mg d-1 of FDOM (quinine equivalents) to the coastal ocean per meter of shoreline. About 11% of this input was related to fresh SGD, while 89% were related to saline SGD resulting from FDOM production within the shallow aquifer. If these fluxes are representative of the Florida Gulf Coast, SGD-derived FDOM fluxes would be equivalent to at least 18% of the potential regional riverine FDOM inputs. To reduce uncertainties related to the scarcity of FDOM data, further investigations of river and groundwater FDOM inputs in Florida and elsewhere are necessary.

  12. [Variation Characteristics and Sources of Polycyclic Aromatic Hydrocarbons in Karst Subterranean River During Rainfall Events].

    Science.gov (United States)

    Jiang, Ze-li; Sun, Yu-chuan; Wang, Zun-bo; Liang, Zuo-bing; Ren, Kun; Xie, Zheng-lan; Zhang, Mei; Liao, Yu

    2015-11-01

    The water samples were continuously collected at the outlet of Nanshan Laolongdong subterranean river basin, which is located in Chongqing, during the rainfall event in June 2014. Sixteen priority polycyclic aromatic hydrocarbons (PAHs) in water were quantitatively analyzed by gas chromatography-mass spectrometry (GC-MS). The objectives of this study were to reveal the variation characteristics and sources of PAH16 in karst subterranean river during the rainfall event. The results showed that the subterranean river responded promptly to the rainfall, and there were four peaks of the total concentrations of PAH16, two peaks occurred during the flow rise stage, the others were in the maximum flow and flow decline stages. The total concentrations of PAH16 ranged 101-3 624 ng x L(-1), with a mean of 578 ng x L(-1), the total concentrations of 7 carcinogenic PAHs ranged ND-336 ng x L(-1), with a mean of 31.1 ng x L(-1). The PAH compositional profiles were dominated by 2,3-ring compounds, which accounted for 86.17% of the total concentrations of PAH16. The total concentrations of PAH16 were most influenced by the rainfall, through the cleaning of atmospheric pollutants by the rain and the scouring of the surface contaminants by the rainfall runoff. The PAHs in water mainly originated from the incomplete combustion of petroleum products and fossil fuels such as coal, as well as natural digenetic process. Compared to other areas in the world, the concentrations of PAH16 were generally at moderately polluted and heavily polluted levels. PMID:26910994

  13. Management of pest mole crickets in Florida and Puerto Rico with a nematode and parasitic wasp

    International Nuclear Information System (INIS)

    Non-indigenous invasive mole crickets, Scapteriscus vicinus Scudder (Orthoptera: Gryllotalpidae) in Florida and S. didactylus (Latreille) (the 'changa') in Puerto Rico, are being managed with an entomopathogenic nematode, Steinernema scapterisci (Nguyen and Smart) (Rhabditida: Steinernematidae), and a parasitic wasp, Larra bicolor L. (Hymenoptera: Sphecidae). Pest mole cricket populations have declined by 95% in north central Florida since these specialist natural enemies were released and established in the 1980s. Commercial production of the nematode was initiated, nearly 70 billion were applied in 34 Florida counties, and their establishment, spread, and impact on mole crickets were monitored. The infected mole crickets dispersed the nematode rapidly, so that within 6 months these parasites were present in most of the insects trapped in experimental pastures. Three years later, mole cricket populations were reduced to acceptable levels and the bahiagrass had recovered. The nematode was released for the first time in Puerto Rico during 2001 and has persisted; the wasp was introduced in the late 1930s. The geographical distribution of the wasp is being expanded in Florida and Puerto Rico by planting plots of Spermacoce verticillata (L.), a wildflower indigenous to Puerto Rico and widely distributed in southern Florida. Pastures, sod farms, golf courses, landscapes, and vegetable farms in Florida and Puerto Rico are benefiting from biological control of invasive mole crickets. (author)

  14. Remarks on the earthworm genus Helodrilus Hoffmeister, 1845 with new epigean and subterranean records (Oligochaeta, Lumbricidae

    Directory of Open Access Journals (Sweden)

    Tímea Szederjesi

    2014-11-01

    Full Text Available The earthworm genus Helodrilus Hoffmeister, 1845 is shortly reviewed. Its special semi-aquatic and subterranean way of life and its consequences to the taxonomy of the genus is discussed. Several new occurrences of some little-known Helodrilus species are given including new country records of H. oculatus for Hungary and H. putricola putricola for Portugal. Examining a topotype of H. hachiojii revealed presence of saccular nephridial bladders consequently, here we propose its transposal to the genus Eisenia as E. hachiojii (Blakemore, 2007 comb. nov.

  15. Energetic expenditure during vocalization in pups of the subterranean rodent Ctenomys talarum

    Science.gov (United States)

    Schleich, Cristian Eric; Busch, Cristina

    2004-11-01

    Theoretical signaling models predict that to be honest, begging vocalizations must be costly. To test this hypothesis, oxygen consumption was measured during resting and begging (i.e., vocalizing) activities in pups of the subterranean rodent Ctenomys talarum by means of open-flow respirometry. No statistical differences in individual oxygen consumption between resting and calling pups ranging in age from day 2 to day 20 were found. Given these data, begging calls of C. talarum could not be considered as honest advertisements of offspring need, contrary to what suggested by the behavioral observations of the mother and pups during the nestling period.

  16. Subterranean glacial spillways: an example from the karst of South Wales, UK

    OpenAIRE

    Farrant, Andrew R.; Simms, Michael J.; Noble, Stephen R.

    2013-01-01

    Many karst areas in the UK have been glaciated one or more times during the last 0.5 Ma, yet there are few documented examples of caves in these regions being affected by glacial processes other than erosion. The karst of South Wales is one area where sub or pro-glacial modification of pre-existing caves is thought to occur. Evidence from the Ogof Draenen cave system suggests that caves can sometimes act as subterranean glacial ‘underspill’ channels for melt-water. This cave, one of the longe...

  17. Temporarily plugging a subterranean reservoir with a self-foaming aqueous solution

    Energy Technology Data Exchange (ETDEWEB)

    Richardson, E.A.; Scheuerman, R.F.; Berkshire, D.C.; Reisberg, J.; Lybarger, J.H.

    1980-11-11

    Portions of a subterranean reservoir are temporarily plugged by injecting an aqueous liquid solution which contains nitrogen gas-generating reactants, a foaming surfactant and a pH controlling system arranged so that the solution remains relatively unreactive within the well but forms a relatively immobile foam within the pores or other openings within the reservoir formation. The invention provides a particularly preferred procedure for diverting a treating fluid into the normally less permeable portions of a reservoir. In that procedure, the pressure on the injected fluid is controlled to cause a preferential breaking of some or all of the foam within the most permeable openings. 10 claims.

  18. Literature survey, bibliographic analysis and a taxonomic catalogue of subterranean fauna from Portugal

    Directory of Open Access Journals (Sweden)

    Ana Reboleira

    2013-02-01

    Full Text Available A bibliographic analysis of the hypogean biological studies in Portugal is made, compiling 138 publications related to the subterranean invertebrate fauna, since its begining in 1870 until November 2012.A catalogue of hypogean endemic taxa is provided, listing 27 troglobionts and 63 stygobionts, described to be obligate hypogean and endemic from mainland Portugal (Macaronesian archipelagos excluded.The first impetus on troglobiont studies was provided by the prospections of Barros Machado during 1940’s and by an expedition of Lindberg in the spring of 1961; and the major information about stygobiont species was provided by the former Instituto de Zoologia “Dr. Augusto Nobre” from Porto University.

  19. The Mole as an Explanatory Device: How Do You Know a Mole if You See One? A Manual for Chemistry Students. Sample Teaching Materials: The Explanatory Modes Project.

    Science.gov (United States)

    Roberts, Douglas A.

    This booklet is designed to supplement the study of introductory chemistry. It deals particularly with the mole concept but also includes ideas for analyzing the kinds of statements that appear in all science textbooks and scientific writing. The material in the booklet should be studied after the completion of an introductory textbook study of…

  20. Blind Friendly Maps

    OpenAIRE

    Červenka, Petr; Břinda, Karel; Seifert, Radek; Hofman, Petr

    2016-01-01

    Space concept of the surrounding area is one of the most important preconditions of the independent mobility and orientation of the blind people. Tactile maps are considered to be the most appropriate source of spatial information. One of the main problems of the tactile maps usage is their problematic accessibility for the blind users since they are not available in time and with up-to-date content. The map production is a matter of tedious manual work and a result of expensive and time-cons...

  1. Models for the Blind

    OpenAIRE

    Jan Eric Olsén

    2014-01-01

    When displayed in museum cabinets, tactile objects that were once used in the education of blind and visually impaired people, appear to us, sighted visitors, as anything but tactile. We cannot touch them due to museum policies and we can hardly imagine what it would have been like for a blind person to touch them in their historical context. And yet these objects are all about touch, from the concrete act of touching something to the norms that assigned touch a specific pedagogical role in n...

  2. Sharing the Space: Distribution, Habitat Segregation and Delimitation of a New Sympatric Area of Subterranean Rodents

    Science.gov (United States)

    Kubiak, Bruno Busnello; Galiano, Daniel; de Freitas, Thales Renato Ochotorena

    2015-01-01

    Subterranean rodents of the genus Ctenomys usually present an allopatric or parapatric distribution. Currently, two cases of sympatry have been recognized for the genus in the coastal dunes of southern Argentina and southern Brazil. In this context, they are ideal models to test hypotheses about the factors that delimit the patterns of space use and to understand interspecific interactions in small mammals. We investigated the vegetation structure, plant biomass and soil hardness selected by two species of subterranean rodents (Ctenomys flamarioni and C. minutus) when distributed in sympatry and allopatry from nine different areas along the line of coastal dunes in southern Brazil. In addition, our work presents a new record of a third area of sympatry for the genus Ctenomys. Ctenomys flamarioni and C. minutus show habitat segregation in the area where they occur in sympatry. These species show segregation in their selection of microhabitats, differing in relation to soil hardness, plant biomass, and plant cover. Ctenomys flamarioni showed a distinction in habitat selection when occurring in allopatry and sympatry, whereas C. minutus selected the same habitat characteristics under both conditions. A possible explanation to the observed pattern is that these species have acquired different adaptations over time which allows them the ability to exploit different resources and thus avoid competitive interactions all together. PMID:25856399

  3. Potential of kaolin-based particle film barriers for Formosan subterranean termite (Isoptera: Rhinotermitidae) control

    Science.gov (United States)

    Wiltz, B.A.; Woodson, W.D.; Puterka, G.J.

    2010-01-01

    Effects of three particle film products on Formosan subterranean termites, Coptotermes formosanus Shiraki, were evaluated in feeding, tunneling, and contact assays. The particle films, hydrophobic M96-018 and hydrophilic Surround and Surround WP are based on the inert clay mineral kaolin. In 2-week long no-choice feeding tests, significant mortality occurred only with M96-018-coated wood. When a choice was provided, M96-018 and Surround were consumed at higher rates than untreated wood. Surround WP did not differ from controls in either test. In the tunneling assay termites were given the option of crossing a kaolin-sand mixture to reach an alternate food source. After 3-weeks, rates of 1% and 5% M96-018 provided an effective barrier to Formosan termite tunneling, while termites were not stopped by rates as high as 20% Surround and Surround WP. Dust treatments of all three formulations caused significant increases in mortality within 24 h, with mortality rates ranging from 72.0 - 97.3% within 72 h of treatment. The particle films were most effective when moisture levels were low, suggesting that desiccation was the mechanism for mortality. All particle films showed potential for use in above ground applications while hydrophobic M06-018 has the most potential as a soil barrier to subterranean termites.

  4. Resistance of Particleboards Made from Fast-Growing Wood Species to Subterranean Termite Attack.

    Science.gov (United States)

    Hermawan, Dede; Hadi, Yusuf S; Fajriani, Esi; Massijaya, Muhamad Y; Hadjib, Nurwati

    2012-01-01

    Laboratory-made particleboards were tested for their resistance to subterranean termite, Coptotermes curvignathus Holmgren (Order Isoptera, Family Termitidae) by Indonesian standard SNI 01.7207-2006, during four weeks and at the end of the test their mass loss percentage and feeding rate were determined. Particleboards consisted of: jabon (Anthocephalus cadamba, Family Rubiacea) with a density of 0.41 g/cm³; sungkai (Peronema canescens, Family Verbenaceae) with a density of 0.46 g/cm³; mangium (Acacia mangium, Family Rhamnaceae) with a density of 0.60 g/cm³ separately and the three species mixture at a rate of 1:1:1. Densities of the boards were targetted at 0.60 g/cm³ and 0.80 g/cm³ by using 12% urea formaldehyde as binder with 2% paraffin as additive based on oven dry wood particle weight. The hand-formed mats and hot-pressing at 130 °C and 2.45 MPa for 10 min were applied. The results showed that particleboards density did not affect mass loss and feeding rate, but the particleboards made from higher density wood resulted in higher resistance to subterranean termite attack. The most resistant particleboards were made of magium, followed by sungkai, mixed species, and jabon. PMID:26466542

  5. Uranium and barium cycling in a salt wedge subterranean estuary: The influence of tidal pumping

    Science.gov (United States)

    Santos, I.R.; Burnett, W.C.; Misra, S.; Suryaputra, I.G.N.A.; Chanton, J.P.; Dittmar, T.; Peterson, R.N.; Swarzenski, P.W.

    2011-01-01

    The contribution of submarine groundwater discharge (SGD) to oceanic metal budgets is only beginning to be explored. Here, we demonstrate that biogeochemical processes in a northern Florida subterranean estuary (STE) significantly alter U and Ba concentrations entering the coastal ocean via SGD. Tidal pumping controlled the distribution of dissolved metals in shallow beach groundwater. Hourly observations of intertidal groundwaters revealed high U and low Ba concentrations at high tide as a result of seawater infiltration into the coastal aquifer. During ebb tide, U decreased and Ba increased due to freshwater dilution and, more importantly, biogeochemical reactions that removed U and added Ba to solution. U removal was apparently a result of precipitation following the reduction of U(VI) to U(IV). A significant correlation between Ba and dissolved organic carbon (DOC) in shallow beach groundwaters implied a common source, likely the mineralization of marine particulate organic matter driven into the beach face by tidal pumping. In deeper groundwaters, where the labile organic matter had been depleted, Ba correlated with Mn. We estimate that net SGD fluxes were − 163 and + 1660 μmol m− 1 d− 1 for U and Ba, respectively (or − 1 and + 8 μmol m− 2 d− 1 if a 200-m wide seepage area is considered). Our results support the emerging concept that subterranean estuaries are natural biogeochemical reactors where metal concentrations are altered relative to conservative mixing between terrestrial and marine endmembers. These deviations from conservative mixing significantly influence SGD-derived trace metal fluxes.

  6. Molting and cuticle deposition in the subterranean trichoniscid Titanethes albus (Crustacea, Isopoda

    Directory of Open Access Journals (Sweden)

    Miloš Vittori

    2012-03-01

    Full Text Available Terrestrial isopods are a suitable group for the study of cuticle synthesis and calcium dynamics because they molt frequently and have evolved means to store calcium during molt. Little data is currently available on molting in Synochaeta and subterranean isopods. We studied the molting dynamics in the subterranean trichoniscid Titanethes albus under laboratory conditions and performed a microscopic investigation of sternal CaCO3 deposits and the tergal epithelium during molt in this species. In accordance with its lower metabolic rate, molting in the laboratory is roughly 2–3 times less frequent in T. albus than would be expected for an epigean isopod under similar conditions. Animals assumed characteristic postures following the molt of each body half and did not consume the posterior exuviae after posterior molt. The structure of sternal calcium deposits and the ultrastructural characteristics of the epidermis during cuticle formation in T. albus are similar to those described in representatives of Ligiidae. During the deposition of the exocuticle, the apical plasma membrane of epidermal cells forms finger-like extensions and numerous invaginations. In the ecdysial space of individuals in late premolt we observed cellular extensions surrounded by bundles of tubules.

  7. Resistance of Particleboards Made from Fast-Growing Wood Species to Subterranean Termite Attack

    Directory of Open Access Journals (Sweden)

    Nurwati Hadjib

    2012-05-01

    Full Text Available Laboratory-made particleboards were tested for their resistance to subterranean termite, Coptotermes curvignathus Holmgren (Order Isoptera, Family Termitidae by Indonesian standard SNI 01.7207–2006, during four weeks and at the end of the test their mass loss percentage and feeding rate were determined. Particleboards consisted of: jabon (Anthocephalus cadamba, Family Rubiacea with a density of 0.41 g/cm3; sungkai (Peronema canescens, Family Verbenaceae with a density of 0.46 g/cm3; mangium (Acacia mangium, Family Rhamnaceae with a density of 0.60 g/cm3 separately and the three species mixture at a rate of 1:1:1. Densities of the boards were targetted at 0.60 g/cm3 and 0.80 g/cm3 by using 12% urea formaldehyde as binder with 2% paraffin as additive based on oven dry wood particle weight. The hand-formed mats and hot-pressing at 130 °C and 2.45 MPa for 10 min were applied. The results showed that particleboards density did not affect mass loss and feeding rate, but the particleboards made from higher density wood resulted in higher resistance to subterranean termite attack. The most resistant particleboards were made of magium, followed by sungkai, mixed species, and jabon.

  8. Testing Children for Color Blindness

    Science.gov (United States)

    ... Español Eye Health / News Testing Children for Color Blindness Written by: Shirley Dang Apr. 03, 2014 New ... shows that kids can be tested for color blindness as soon as age 4, finds Caucasian boys ...

  9. Postural control in blind subjects

    Directory of Open Access Journals (Sweden)

    Antonio Vinicius Soares

    2011-12-01

    Full Text Available Objective: To analyze postural control in acquired and congenitally blind adults. Methods: A total of 40 visually impaired adults participated in the research, divided into 2 groups, 20 with acquired blindness and 20 with congenital blindness - 21 males and 19 females, mean age 35.8 ± 10.8. The Brazilian version of Berg Balance Scale and the motor domain of functional independence measure were utilized. Results: On Berg Balance Scale the mean for acquired blindness was 54.0 ± 2.4 and 54.4 ± 2.5 for congenitally blind subjects; on functional independence measure the mean for acquired blind group was 87.1 ± 4.8 and 87.3 ± 2.3 for congenitally blind group. Conclusion: Based upon the scale used the results suggest the ability to control posture can be developed by compensatory mechanisms and it is not affected by visual loss in congenitally and acquired blindness.

  10. The blind hens’ challenge

    DEFF Research Database (Denmark)

    Sandøe, Peter; Hocking, Paul M.; Forkman, Björn;

    2014-01-01

    repellent, yet 'welfare-only' positions appear to be committed to endorsing this possibility if it produces welfare gains. We call this the 'Blind Hens' Challenge'. In this paper, we argue that there are both empirical and theoretical reasons why even those adopting 'welfare-only' views should be concerned...

  11. FLIPPS for the Blind

    DEFF Research Database (Denmark)

    Bothe, Hans-Heinrich; Al-Hamdani, Sermed

    2010-01-01

    (blind person) receives the reflected light from the objects and, based on brain plasticity principles, can interactively learn to construct a mental image of the objects and of the scenery. The FLIPPS idea is based on sensory substitution theory; here, substituting visual inputs by haptic vibrations....

  12. Oplysningens blinde vinkler

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg; Hendricks, Vincent Fella

    manipulation og fordrejning, til at påvirke menneskers overvejelser, beslutninger og handlinger, både individuelt og kollektivt, hvilket i sidste ende kan få betydning for de demokratiske processer. Oplysningens blinde vinkler gennemgår en række informationsfænomener, som optræder i vores dagligdag, og den...

  13. Oplysnigens blinde vinkler

    DEFF Research Database (Denmark)

    Hendricks, Vincent Fella; Hansen, Pelle Guldborg

    manipulation og fordrejning, til at påvirke menneskers overvejelser, beslutninger og handlinger, både individuelt og kollektivt, hvilket i sidste ende kan få betydning for de demokratiske processer. Oplysningens blinde vinkler gennemgår en række informationsfænomener, som optræder i vores dagligdag, og den...

  14. Blind Deconvolution Imaging

    Czech Academy of Sciences Publication Activity Database

    Šroubek, Filip; Šorel, Michal

    Berlin : Wiley, 2011 - (Cristobal, G.; Schelkens, P.; Thienpont, H.), s. 529-548 ISBN 978-3-527-40956-3 R&D Projects: GA MŠk 1M0572; GA ČR(CZ) GA102/08/1593 Institutional research plan: CEZ:AV0Z10750506 Keywords : blind deconvolution * space-variant deconvolution Subject RIV: JD - Computer Applications, Robotics

  15. Trace element geochemistry of groundwater in a karst subterranean estuary (Yucatan Peninsula, Mexico)

    Science.gov (United States)

    Gonneea, Meagan Eagle; Charette, Matthew A.; Liu, Qian; Herrera-Silveira, Jorge A.; Morales-Ojeda, Sara M.

    2014-05-01

    Trace element cycling within subterranean estuaries frequently alters the chemical signature of groundwater and may ultimately control the total chemical load to the coastal ocean associated with submarine groundwater discharge. Globally, karst landscapes occur over 12% of all coastlines. Subterranean estuaries in these regions are highly permeable, resulting in rapid infiltration of precipitation and transport of groundwater to the coast, and the predominant carbonate minerals are readily soluble. We studied the chemical cycling of barium (Ba), strontium (Sr), manganese (Mn), uranium (U), calcium (Ca) and radium (Ra) within the carbonate karst subterranean estuary of the Yucatan Peninsula, which is characterized by a terrestrial groundwater lens overlying marine groundwater intrusion with active submarine discharge through coastal springs. Terrestrial groundwater calcium (1-5 mmol kg-1) and alkalinity (3-8 mmol kg-1) are enriched over that predicted by equilibrium between recharging precipitation and calcite, which can be accounted for by groundwater organic matter respiration and subsequent dissolution of calcite, dolomite and gypsum. There is a close agreement between the observed terrestrial groundwater Sr/Ca, Mn/Ca, Ba/Ca and Ra/Ca and that predicted by equilibrium dissolution of calcite, thus the trace element content of terrestrial groundwater is largely determined by mineral dissolution. Subsequent mixing between terrestrial groundwater and the ocean within the actively discharging springs is characterized by conservative mixing of Sr, Mn, Ba and Ca, while U is variable and Ra displays a large enrichment (salinity: 1.9-34.9, Ba: 60-300 nmol kg-1, Sr: 15-110 μmol kg-1, U: 0.3-35 nmol kg-1, Mn: 0.3-200 nmol kg-1, Ca: 4.3-12.9 mmol kg-1, 226Ra: 18-2140 dpm 100 L-1). The deep groundwater sampled through cenotes, local dissolution features, is typified by elevated Ba, Sr, Ca, Mn and Ra and the absence of U within marine groundwater, due to enhanced dissolution

  16. Corneal blindness and xenotransplantation.

    Science.gov (United States)

    Lamm, Vladimir; Hara, Hidetaka; Mammen, Alex; Dhaliwal, Deepinder; Cooper, David K C

    2014-01-01

    Approximately 39 million people are blind worldwide, with an estimated 285 million visually impaired. The developing world shoulders 90% of the world's blindness, with 80% of causative diseases being preventable or treatable. Blindness has a major detrimental impact on the patient, community, and healthcare spending. Corneal diseases are significant causes of blindness, affecting at least 4 million people worldwide. The prevalence of corneal disease varies between parts of the world. Trachoma, for instance, is the second leading cause of blindness in Africa, after cataracts, but is rarely found today in developed nations. When preventive strategies have failed, corneal transplantation is the most effective treatment for advanced corneal disease. The major surgical techniques for corneal transplantation include penetrating keratoplasty (PK), anterior lamellar keratoplasty, and endothelial keratoplasty (EK). Indications for corneal transplantation vary between countries, with Fuchs' dystrophy being the leading indication in the USA and keratoconus in Australia. With the exception of the USA, where EK will soon overtake PK as the most common surgical procedure, PK is the overwhelming procedure of choice. Success using corneal grafts in developing nations, such as Nepal, demonstrates the feasibility of corneal transplantation on a global scale. The number of suitable corneas from deceased human donors that becomes available will never be sufficient, and so research into various alternatives, for example stem cells, amniotic membrane transplantation, synthetic and biosynthetic corneas, and xenotransplantation, is progressing. While each of these has potential, we suggest that xenotransplantation holds the greatest potential for a corneal replacement. With the increasing availability of genetically engineered pigs, pig corneas may alleviate the global shortage of corneas in the near future. PMID:25268248

  17. The willed blindness of humans

    DEFF Research Database (Denmark)

    Gjerris, Mickey

    2012-01-01

    This paper describes how we seem to live in a willed blindness towards the effects that our meat production and consumption have on animals, the environment and the climate. It is a willed blindness that cannot be explained by either lack of knowledge or scientific uncertainty. The blindness...

  18. Influence of Dry Soil on the Ability of Formosan Subterranean Termites (Coptotermes formosanus) to Locate Food Sources

    Science.gov (United States)

    The effect of barriers of dry soil on the ability of Formosan subterranean termites, Coptotermes formosanus Shiraki, to construct tunnels and find food was evaluated. Termite movement and wood consumption in a three-chambered apparatus were compared for treatments where the soil in the center contai...

  19. Influence of dry soil on the ability of Formosan Subterranean Termites, Coptotermes formosanus, to locate food sources.

    Science.gov (United States)

    The effect of barriers of dry soil on the ability of Formosan subterranean termites, Coptotermes formosanus Shiraki, to construct tunnels and find food was evaluated. Termite movement and wood consumption in a three-chambered apparatus were compared for treatments where the soil in the center contai...

  20. Use of biocides for the control of fungal outbreaks in subterranean environments: The case of the Lascaux Cave in France

    Czech Academy of Sciences Publication Activity Database

    Martín-Sánchez, P.M.; Nováková, Alena; Bastian, F.; Alabouvette, C.; Saiz-Jimenez, C.

    2012-01-01

    Roč. 46, č. 7 (2012), s. 3762-3770. ISSN 0013-936X Grant ostatní: Spanish Ministry of Science and Innovation(ES) TCP CSD2007-00058 Institutional support: RVO:60077344 Keywords : fungal outbreaks * subterranean environments * Lascaux Cave Subject RIV: EH - Ecology, Behaviour Impact factor: 5.257, year: 2012

  1. Incidence and review of hydatidiform mole; chorioadenoma, destruens and chorio carcinoma in Mirza Kochek Khan Hospita

    Directory of Open Access Journals (Sweden)

    Ghaffari V

    1995-04-01

    Full Text Available Initial management, incidence and review of hydatidiform mole, chorioadenoma and destruens and chorio carcinoma in Mirza Kochek khan hospital department of ob.gyn and gynecology oncology of women's hospital Tehran-Iran school of medicin from September 1985 to March 1990, 209 patients received primary management for hydatidiform mole at oncology department of Mirza Kochek Khan hospital medical school of Tehran Iran. All of these women HAD complete record available for analysis, of these, 167 women bydatidiform mole, 12 patients chorioadenoma-destruens 30 patients chorio carcinoma a survey was made of factors likely to provide an important clinical perspective patient aye and the status of pregnancy were noted. 41 patient only sharp curettage and 55 patients suction curettage to remove the hydatidiform mole. 97 patient require chemo terapy, suction curettage of the uterus is clearly the best means of management in the most cases their eyperince documents that hydatidiform mole is an high risk pregnancy that requires prompt and in tensive management.

  2. Blind Decryption and Privacy Protection

    Directory of Open Access Journals (Sweden)

    Mohammed Al-Fayoumi

    2005-01-01

    Full Text Available Blind decryption is an efficient way of protecting customer’s privacy in online marketing over the Internet (i.e. Hiding information about which goods a user purchases from the vendor. In this study, the RSA based blind decryption is simply transposed from an identical protocol as the Chaum’s blind signature scheme and the blind decryption protocol for the Elgamal encryption scheme is suggested. In addition, the difference between the known RSA based blind decryption protocol and our proposed protocol is examined in applications to protect copyright subjects of e-commerce documents over the internet.

  3. A Mole for Warm Magnetic and Optical Measurements of LHC Dipoles

    CERN Document Server

    Bottura, L; Deferne, G; Glöckner, C; Jansen, H; Köster, A; Legrand, P; Rijllart, A; Sievers, P

    2000-01-01

    A new rotating coil probe (a mole) has been developed for the simultaneous measurement of the magnetic field and magnetic axis of warm superconducting LHC dipoles and associated corrector windings. The mole houses a radial rotating coil and travels inside the magnet aperture by means of an externally driven two-way traction belt. The coil is rotated by an on-board piezo motor, being tested in view of future devices for cold measurements as the only type of motor compatible with strong magnetic fields. A virtual light spot is generated in the coil center by a LED source. The position of this light spot is measured from the outside by a system including a telescope, a CCD camera and a DSP. Jigs on reference granite tables are used to transfer the optical measurements to the magnet fiducials. We describe here the main characteristics and performance of the mole

  4. Unconditionally verifiable blind computation

    CERN Document Server

    Fitzsimons, Joseph F

    2012-01-01

    Blind Quantum Computing (BQC) allows a client to have a server carry out a quantum computation for them such that the client's input, output and computation remain private. Recently the authors together with Broadbent proposed a universal unconditionally secure BQC scheme where the client only needs to be able to prepare single qubits in separable states randomly chosen from a finite set and send them to the server, who has the balance of the required quantum computational resources. A desirable property for any BQC protocol is verification, whereby the client can verify with high probability whether the server has followed the instructions of the protocol, or if there has been some deviation resulting in a corrupted output state. A verifiable BQC protocol can be viewed as an interactive proof system leading to consequences for complexity theory. In this paper we extend the BQC protocol presented in [Broadbent, Fitzsimons and Kashefi, FOCS 2009 p517] with new functionality allowing blind computational basis m...

  5. Blind Quantum Computation

    CERN Document Server

    Arrighi, P; Arrighi, Pablo; Salvail, Louis

    2003-01-01

    We investigate the possibility of having someone carry out the work of executing a function for you, but without letting him learn anything about your input. Say Alice wants Bob to compute some well-known function f upon her input x, but wants to prevent Bob from learning anything about x. The situation arises for instance if client Alice has limited computational resources in comparison with mistrusted server Bob, or if x is an inherently mobile piece of data. Could there be a protocol whereby Bob is forced to compute f(x) "blindly", i.e. without observing x? We provide such a blind computation protocol for the class of functions which admit an efficient procedure to generate random input-output pairs, e.g. factorization. The setting is quantum, the security is unconditional, the eavesdropper is as malicious as can be. Keywords: Secure Circuit Evaluation, Secure Two-party Computation, Information Hiding, Information gain vs disturbance.

  6. Influence of sea level rise on iron diagenesis in an east Florida subterranean estuary

    Science.gov (United States)

    Roy, M.; Martin, J.B.; Cherrier, J.; Cable, J.E.; Smith, C.G.

    2010-01-01

    Subterranean estuary occupies the transition zone between hypoxic fresh groundwater and oxic seawater, and between terrestrial and marine sediment deposits. Consequently, we hypothesize, in a subterranean estuary, biogeochemical reactions of Fe respond to submarine groundwater discharge (SGD) and sea level rise. Porewater and sediment samples were collected across a 30-m wide freshwater discharge zone of the Indian River Lagoon (Florida, USA) subterranean estuary, and at a site 250. m offshore. Porewater Fe concentrations range from 0.5 ??M at the shoreline and 250. m offshore to about 286 ??M at the freshwater-saltwater boundary. Sediment sulfur and porewater sulfide maxima occur in near-surface OC-rich black sediments of marine origin, and dissolved Fe maxima occur in underlying OC-poor orange sediments of terrestrial origin. Freshwater SGD flow rates decrease offshore from around 1 to 0.1. cm/day, while bioirrigation exchange deepens with distance from about 10. cm at the shoreline to about 40. cm at the freshwater-saltwater boundary. DOC concentrations increase from around 75 ??M at the shoreline to as much as 700 ??M at the freshwater-saltwater boundary as a result of labile marine carbon inputs from marine SGD. This labile DOC reduces Fe-oxides, which in conjunction with slow discharge of SGD at the boundary, allows dissolved Fe to accumulate. Upward advection of fresh SGD carries dissolved Fe from the Fe-oxide reduction zone to the sulfate reduction zone, where dissolved Fe precipitates as Fe-sulfides. Saturation models of Fe-sulfides indicate some fractions of these Fe-sulfides get dissolved near the sediment-water interface, where bioirrigation exchanges oxic surface water. The estimated dissolved Fe flux is approximately 0.84 ??M Fe/day per meter of shoreline to lagoon surface waters. Accelerated sea level rise predictions are thus likely to increase the Fe flux to surface waters and local primary productivity, particularly along coastlines where

  7. Mechanical performance of rat, mouse and mole spring traps, and possible implications for welfare performance.

    Directory of Open Access Journals (Sweden)

    Sandra E Baker

    Full Text Available Lethal spring traps are widely used for killing small mammals in the UK. Many require government approval, based primarily on humaneness. However, mole traps and break-back traps for rats and mice are exempt; those available vary widely in price and apparent quality. The EU is considering implementing a Trapping Directive that would alter UK legislation, and a recent report advised the EU that trapping legislation should cover all trapped species and encourage improvement of traps. Mechanical trap performance is often used as an indicator of welfare impact. We examined the mechanical evidence for scope to improve the welfare standards of rat, mouse and mole spring traps. We measured mechanical performance among a range of rat, mouse and mole traps. Impact momentum values varied 6-8 fold, and clamping force values 4-5.5 fold, among traps for killing each species. There was considerable overlap in the performance of rat and mouse traps. Trap-opening angle and spring type were related to impact momentum and clamping force in traps for both species. There was no relationship between price and mechanical performance in traps for any species, except talpa mole traps. We are unable to judge the direct welfare impact of the traps tested, but rather the potential welfare threat associated with their exemption from approval. The wide variation in mechanical performance in traps for each species, overlap in performance between rat and mouse traps and increasing availability of weaker plastic rodent traps indicate considerable scope for improving the humaneness of spring traps for rats, mice and moles. We conclude that all such traps should be subject to the UK approval process. New welfare categories might improve trap standards further. Our results could also help improve rodent trap design and assist consumers in selecting more powerful traps. Many thousands of rats, mice and moles might benefit.

  8. Extended longevity of reproductives appears to be common in Fukomys mole-rats (Rodentia, Bathyergidae.

    Directory of Open Access Journals (Sweden)

    Philip Dammann

    Full Text Available African mole-rats (Bathyergidae, Rodentia contain several social, cooperatively breeding species with low extrinsic mortality and unusually high longevity. All social bathyergids live in multigenerational families where reproduction is skewed towards a few breeding individuals. Most of their offspring remain as reproductively inactive "helpers" in their natal families, often for several years. This "reproductive subdivision" of mole-rat societies might be of interest for ageing research, as in at least one social bathyergid (Ansell's mole-rats Fukomys anselli, breeders have been shown to age significantly slower than non-breeders. These animals thus provide excellent conditions for studying the epigenetics of senescence by comparing divergent longevities within the same genotypes without the inescapable short-comings of inter-species comparisons. It has been claimed that many if not all social mole-rat species may have evolved similar ageing patterns, too. However, this remains unclear on account of the scarcity of reliable datasets on the subject. We therefore analyzed a 20-year breeding record of Giant mole-rats Fukomys mechowii, another social bathyergid species. We found that breeders indeed lived significantly longer than helpers (ca. 1.5-2.2fold depending on the sex, irrespective of social rank or other potentially confounding factors. Considering the phylogenetic positions of F. mechowii and F. anselli and unpublished data on a third Fukomys-species (F. damarensis showing essentially the same pattern, it seems probable that the reversal of the classic trade-off between somatic maintenance and sexual reproduction is characteristic of the whole genus and hence of the vast majority of social mole-rats.

  9. Mole ghrelin: cDNA cloning, gene expression, and diverse molecular forms in Mogera imaizumii.

    Science.gov (United States)

    Satou, Motoyasu; Kaiya, Hiroyuki; Nishi, Yoshihiro; Shinohara, Akio; Kawada, Shin-Ichiro; Miyazato, Mikiya; Kangawa, Kenji; Sugimoto, Hiroyuki

    2016-06-01

    Here, we describe cDNA cloning and purification of the ghrelin gene sequences and ghrelin peptides from the Japanese true mole, Mogera imaizumii. The gene spans >2.9kbp, has four exons and three introns, and shares structural similarity with those of terrestrial animals. Mature mole ghrelin peptide was predicted to be 28 amino acids long (GSSFLSPEHQKVQQRKESKKPPSKPQPR) and processed from a prepropeptide of 116 amino acids. To further elucidate molecular characteristics, we purified ghrelin peptides from mole stomach. By mass spectrometry, we found that the mole ghrelin peptides had higher ratios of the odd-number fatty acids (C9 and C11 as much as C8) attached to the third serine residue than other vertebrate ghrelin. Truncated forms of ghrelins such as [1-27], [1-19], [1-16] and [1-15], and that lacked the 14th glutamine residue (des-Gln14 ghrelin) were produced in the stomach. Marked expression of ghrelin mRNA in lung was observed as in stomach and brain. Phylogenetic analysis indicated that the branch of M. imaizumii has slightly higher dN/dS ratios (the nucleotide substitution rates at non-synonymous and synonymous sites) than did other eulipotyphlans. Peptide length was positively correlated with human ghrelin receptor activation, whereas the length of fatty-acyl chains showed no obvious functional correlation. The basal higher luciferase activities of the 5'-proximal promoter region of mole ghrelin were detected in ghrelin-negative C2C12 cells and hypoxic culture conditions impaired transcriptional activity. These results indicated that moles have acquired diverse species of ghrelin probably through distinctive fatty acid metabolism because of their food preferences. The results provide a gateway to understanding ghrelin metabolism in fossorial animals. PMID:27102942

  10. Tackling Inherited Blindness

    OpenAIRE

    Batten, Matthew L.; Imanishi, Yoshikazu; Tu, Daniel C; Doan, Thuy; Zhu, Li; Pang, Jijing; Glushakova, Lyudmila; Moise, Alexander R.; Baehr, Wolfgang; Van Gelder, Russell N.; Hauswirth, William W.; Rieke, Fred; Palczewski, Krzysztof

    2005-01-01

    Background Leber congenital amaurosis (LCA), a heterogeneous early-onset retinal dystrophy, accounts for ~15% of inherited congenital blindness. One cause of LCA is loss of the enzyme lecithin:retinol acyl transferase (LRAT), which is required for regeneration of the visual photopigment in the retina. Methods and Findings An animal model of LCA, the Lrat −/− mouse, recapitulates clinical features of the human disease. Here, we report that two interventions—intraocular gene therapy and oral ph...

  11. Stochastic Blind Motion Deblurring

    KAUST Repository

    Xiao, Lei

    2015-05-13

    Blind motion deblurring from a single image is a highly under-constrained problem with many degenerate solutions. A good approximation of the intrinsic image can therefore only be obtained with the help of prior information in the form of (often non-convex) regularization terms for both the intrinsic image and the kernel. While the best choice of image priors is still a topic of ongoing investigation, this research is made more complicated by the fact that historically each new prior requires the development of a custom optimization method. In this paper, we develop a stochastic optimization method for blind deconvolution. Since this stochastic solver does not require the explicit computation of the gradient of the objective function and uses only efficient local evaluation of the objective, new priors can be implemented and tested very quickly. We demonstrate that this framework, in combination with different image priors produces results with PSNR values that match or exceed the results obtained by much more complex state-of-the-art blind motion deblurring algorithms.

  12. Twin pregnancy with both complete hydatiform mole and coexistent alive fetus:case report

    Institute of Scientific and Technical Information of China (English)

    Achour Radhouane; Ben Aissa Imen; NEJI Khaled

    2015-01-01

    Twin pregnancy consisting of a complete hydatidiform mole coexisting with a live fetus is a rare condition with an incidence of 1 in 22 000 to 1 in 1 00 000 pregnancies. Clinical information is limited and management is difficult due to the risk of pregnancy complications such as fetal death, vaginal bleeding, preeclampsia, hyperthyroidism, and the risk of persistent gestational trophoblastic disease. Thus, the report described about the change of size and implantation site of the molar mass coexisting with a live fetus is rare especially about sonographic findings such as echo patterns. Recently we experienced a case of complete hydatidiform mole with a healthy infant delivered at term.

  13. Structural, magnetic and microwave properties of barium hexaferrite thick films with different Fe/Ba mole ratio

    International Nuclear Information System (INIS)

    Barium hexaferrite (BaFe12O19) thick films (∼60 µm) with different BaO·xFe2O3 mole ratio (x=5.0–6.0) were prepared by screen printing method. X-ray diffraction analysis confirmed the formation of single phase BaFe12O19 (BaM). Preferential site occupation of Fe3+ ion at five different crystallographic sites, with varied mole ratio was measured by Mössbauer spectroscopy. Vacancy fraction found to be higher at 4f1, 4f2 and 2b sites for mole ratio 5.5 and 5.0 respectively. Magnetic measurement shows that the magnetization (M) and magnetocrystalline anisotropy field (Ha) depends upon mole ratio. M and Ha are found to be maximum for mole ratio 5.5, while the coercivity (Hc) remains constant. Reflection losses (RL) in the frequency range of 12–18 GHz were also studied. Present investigation demonstrates the effect of mole ratio on structural, magnetic and microwave absorption properties of BaM thick films for microwave device applications. - Highlights: • Single phase BaM thick films with different Fe/Ba mole ratio are prepared. • Site preference of Fe ion is estimated by Mössbauer spectroscopy. • Magnetization and magnetocrystalline ansisotropy is found maximum for 5.5 mole ratio. • Absorption frequency found to vary with the mole ratio

  14. Method for the control of solids accompanying hydrocarbon production from subterranean formations

    Energy Technology Data Exchange (ETDEWEB)

    Strubhar, M.K.; Healy, J.C.

    1992-04-21

    This patent describes a method for controlling solids contained in hydrocarbonaceous fluids produced from a subterranean formation. It comprises perforating a wellbore at a productive interval of a hydrocarbonaceous fluid-containing formation; injecting into the productive interval via perforations a fracturing fluid containing a resin-coated self-consolidating particulate material which is of a size and composition sufficient to prop a created fracture and form a permeable consolidated mass therein; fracturing hydraulically the productive interval and thereafter creating a propped fracture with a self-consolidated permeable mass therein as well as within the perforations and wellbore which mass has filtration properties and composition sufficient to restrain solids entrained in the hydrocarbonaceous fluid; and removing mechanically the consolidated permeable mass from the wellbore which allows hydrocarbonaceous fluids to be produced from the formation substantially solids free which solids are restrained by the permeable consolidated mass within the fracture and perforations.

  15. Dynamics of Foraging and Recruitment Behavior in the Asian Subterranean Termite Coptotermes gestroi (Rhinotermitidae

    Directory of Open Access Journals (Sweden)

    Alberto Arab

    2012-01-01

    Full Text Available The present study investigated the trail-following behavior of the subterranean termite Coptotermes gestroi (Wasmann Rhinotermitidae under laboratory conditions. The results showed that workers were the first to initiate the exploration to the food source. When food was discovered they returned to the nest laying a trail for recruiting nestmates to the food source. In this situation, workers always traveled significantly faster when returning from the arenas. Both workers and soldiers were recruited to the food source; however, the soldier/worker proportion was higher during the first phase of the recruitment. When no food was available, the number of recruited nestmates and the speed on their way back to the nest were significantly lower. The results also showed that scout foragers always laid trail pheromones when entering into unknown territories, and that chemical signals found in the food could induce workers of C. gestroi to increase their travel speed.

  16. Structure-activity of valencenoid derivatives and their repellence to the Formosan subterranean termite.

    Science.gov (United States)

    Zhu, Betty C R; Henderson, Gregg; Sauer, Anne M; Yu, Ying; Crowe, William; Laine, Roger A

    2003-12-01

    Eight valencenoid derivatives were evaluated for their repelling activity against Formosan subterranean termites, Coptotermes formosanus Shiraki. Among them, 1,10-dihydronootkatone was the strongest repellent, and valencene was the weakest. Results of the structure-repellency relationships indicated (1) reduction of the ketone group to the alcohol on position 2 of nootkatone curtailed the activity; (2) because of the low activity of valencene relative to nootkatone that the ketone group was essential for repellent activity; (3) reduction of the 1,10 double bond (1,10-dihydronootkatone and tetrahydronootkatone) produced compounds more repellent than nootkatone; (4) the isopropenyl group probably does not participate in binding as evidenced by no significant difference in the repellent activity among nootkatone (double bond between position 11 and 12), isonootkatone (double bond between position 7 and 11), and 11,12-dihydronootkatone. PMID:14969356

  17. Subterranean Microhabitat Dependent Intra Versus Extracellular Enzyme Secretion Capabilities of Deinococcus radiodurans

    Directory of Open Access Journals (Sweden)

    Jayant Biswas

    2015-03-01

    Full Text Available Deinococcus radiodurans is one of the most yet discovered extremophilic microbe, the isolation of which from the various habitats of Kotumsar cave is always a matter of enticement to discover its ecological economics. In the present work we studied the intra versus extracellular alkaline protease and glucose isomerase secretion capabilities of Deinococcus radiodurans; KCB21, KCB50, KCB93 isolated from three distinct subterranean niches of Kotumsar cave. The selected niches/zones were the entrance zone, transient zone and the deep inner zone from where the soil sediments were collected to isolate the bacterial strains. The results revealed high extracellular alkaline protease activity from the Deinococcus radiodurans strain which was isolated from the deeper zones of the cave, whereas no such phenomenon was revealed for glucose isomerase. The possible reason for the obtained results has been discussed.

  18. Characteristics Research of Immersed and Waterlogged Subterranean River System of Reservoir Areas of Hydroelectric Stations

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The karst immersion and waterlogging is one of the typical and the most harmful natural disasters in southern karst areas of China. It is threat to the local production and life for a long time. In recent years, due to the construction of more reservoirs, the disaster became serious. This article takes immersion and waterlogging of Banwer's subterranean rivers in Yantan reservoir area as an example, researches the daily rainfalls reflection to the water level of reservoir depression, discusses characteristics of immersion and waterlogging of the valley, analyzes the disaster index in detail, such as water level process, the highest water level, sensitive rainfall, original waterlogged rainfall and delayed day numbers etc., and provides the reference as a basis to the disaster analysis.

  19. A maze-lover's dream: Burrow architecture, natural history and habitat characteristics of Ansell's mole-rat (Fukomys anselli)

    Czech Academy of Sciences Publication Activity Database

    Šklíba, J.; Mazoch, V.; Patzenhauerová, Hana; Hrouzková, E.; Lövy, M.; Kott, O.; Šumbera, R.

    2012-01-01

    Roč. 77, č. 6 (2012), s. 420-427. ISSN 1616-5047 R&D Projects: GA AV ČR IAA601410802 Institutional support: RVO:68081766 Keywords : Bathyergidae * Burrow system * Sociality * Habitat characteristics * Subterranean mammal * Fukomys anselli Subject RIV: EG - Zoology Impact factor: 1.246, year: 2012

  20. Reading about the Power of Music: "Mole Music" and "Children of the Stone"

    Science.gov (United States)

    Cardany, Audrey Berger

    2016-01-01

    In this article, I review two books that address the power of music for the individual and group. Both books address the benefits of making, learning, and listening to music during times of conflict. The first brief review is David McPhail's picture book "Mole Music." The second is "Children of the Stone: The Power of Music in a…

  1. The Atomic Mass Unit, the Avogadro Constant, and the Mole: A Way to Understanding

    Science.gov (United States)

    Baranski, Andrzej

    2012-01-01

    Numerous articles have been published that address problems encountered in teaching basic concepts of chemistry such as the atomic mass unit, Avogadro's number, and the mole. The origin of these problems is found in the concept definitions. If these definitions are adjusted for teaching purposes, understanding could be improved. In the present…

  2. Background Mole Fractions of Hydrocarbons in North America Determined from NOAA Global Reference Network Data

    Science.gov (United States)

    Mielke-Maday, I.

    2015-12-01

    The National Oceanic and Atmospheric Administration (NOAA) Global Monitoring Division (GMD) maintains a global reference network for over 50 trace gas species and analyzes discrete air samples collected by this network throughout the world at the Earth System Research Laboratory in Boulder, Colorado. In particular, flask samples are analyzed for a number of hydrocarbons with policy and health relevance such as ozone precursors, greenhouse gases, and hazardous air pollutants. Because this global network's sites are remote and therefore minimally influenced by local anthropogenic emissions, these data yield information about background ambient mole fractions and can provide a context for observations collected in intensive field campaigns, such as the Front Range Air Pollution and Photochemistry Experiment (FRAPPE), the Southeast Nexus (SENEX) study, and the DISCOVER-AQ deployments. Information about background mole fractions during field campaigns is critical for calculating hydrocarbon enhancements in the region of study and for assessing the extent to which a particular region's local emissions sources contribute to these enhancements. Understanding the geographic variability of the background and its contribution to regional ambient mole fractions is also crucial for the development of realistic regulations. We present background hydrocarbon mole fractions and their ratios in North America using data from air samples collected in the planetary boundary layer at tall towers and aboard aircraft from 2008 to 2014. We discuss the spatial and seasonal variability in these data. We present trends over the time period of measurements and propose possible explanations for these trends.

  3. Trauma and humanitarian translation in Liberia: the tale of open mole.

    Science.gov (United States)

    Abramowitz, Sharon Alane

    2010-06-01

    The focus of this paper is the intercultural process through which Open Mole and trauma-related mental illnesses are brought together in the postconflict mental health encounter. In this paper, I explore the historical dimension of this process by reviewing the history of Open Mole, and the ways in which it has been interpreted, acted on, and objectified by external observers over the last half-century. Moving into Liberia's recent war and postconflict period, I examine the process by which Open Mole is transformed from a culture-bound disorder into a local idiom of trauma, and how it has become a gateway diagnosis of PTSD-related mental illnesses, and consider how it is produced as an objectified experience of psychiatric disorder in clinical humanitarian contexts. By studying how Open Mole is transformed in the humanitarian encounter, I address the structure and teleology of the humanitarian encounter and challenge some of the foundational assumptions about cultural sensitivity and community-based mental health care in postconflict settings that are prevalent in scholarship and practice today. PMID:20401629

  4. Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

    NARCIS (Netherlands)

    S.L. Macrae (Sheila L.); Q. Zhang (Quanwei); C. Lemetre (Christophe); I. Seim (Inge); R.B. Calder (Robert B.); J.H.J. Hoeijmakers (Jan); Y. Suh (Yousin); V.N. Gladyshev (Vadim N.); A. Seluanov (Andrei); V. Gorbunova (Vera); J. Vijg (Jan); Z.D. Zhang (Zhengdong D.)

    2015-01-01

    textabstractGenome maintenance (GM) is an essential defense system against aging and cancer, as both are characterized by increased genome instability. Here, we compared the copy number variation and mutation rate of 518 GM-associated genes in the naked mole rat (NMR), mouse, and human genomes. GM g

  5. The sense of touch in the star-nosed mole: from mechanoreceptors to the brain.

    Science.gov (United States)

    Catania, Kenneth C

    2011-11-12

    Star-nosed moles are somatosensory specialists that explore their environment with 22 appendages that ring their nostrils. The appendages are covered with sensory domes called Eimer's organs. Each organ is associated with a Merkel cell-neurite complex, a lamellated corpuscle, and a series of 5-10 free nerve endings that form a circle of terminal swellings. Anatomy and electrophysiological recordings suggest that Eimer's organs detect small shapes and textures. There are parallels between the organization of the mole's somatosensory system and visual systems of other mammals. The centre of the star is a tactile fovea used for detailed exploration of objects and prey items. The tactile fovea is over-represented in the neocortex, and this is evident in the modular, anatomically visible representation of the star. Multiple maps of the star are visible in flattened cortical preparations processed for cytochrome oxidase or NADPH-diaphorase. Star-nosed moles are the fastest known foragers among mammals, able to identify and consume a small prey item in 120 ms. Together these behavioural and nervous system specializations have made star-nosed moles an intriguing model system for examining general and specialized aspects of mammalian touch. PMID:21969683

  6. Hydatidiform mole and fetus with normal karyotype: support of a separate entity

    DEFF Research Database (Denmark)

    Vejerslev, L O; Sunde, L; Hansen, B F;

    1991-01-01

    Repetitive hydatidiform mole was observed in four pregnancies. The pregnancies presented with heavy bleeding and vomiting, but the post-evacuation courses were uncomplicated, with rapid regression of serum hCG levels. Cytogenetic investigations, analyses of restriction fragment length polymorphis...

  7. Noise blind test

    OpenAIRE

    H. Cadet

    2006-01-01

    In the aim of characterizing site condition for seismic risk, the microtremor or ambient noise studies have been developed. The main objective of this blind test is to check of the reliability of results, to observe the user subjectivity (array choice, parameters that are user depend) in the noise recordings analyze. Noise records were analysed on single-station with H/V method and with several sensors for array method to determine the dispersion characteristics of the surface-wave part of th...

  8. Blind Quantum Computation

    DEFF Research Database (Denmark)

    Salvail, Louis; Arrighi, Pablo

    2006-01-01

    We investigate the possibility of "having someone carry out the work of executing a function for you, but without letting him learn anything about your input". Say Alice wants Bob to compute some known function f upon her input x, but wants to prevent Bob from learning anything about x. The situa......We investigate the possibility of "having someone carry out the work of executing a function for you, but without letting him learn anything about your input". Say Alice wants Bob to compute some known function f upon her input x, but wants to prevent Bob from learning anything about x....... The situation arises for instance if client Alice has limited computational resources in comparison with mistrusted server Bob, or if x is an inherently mobile piece of data. Could there be a protocol whereby Bob is forced to compute f(x) "blindly", i.e. without observing x? We provide such a blind computation...... protocol for the class of functions which admit an efficient procedure to generate random input-output pairs, e.g. factorization. The cheat-sensitive security achieved relies only upon quantum theory being true. The security analysis carried out assumes the eavesdropper performs individual attacks....

  9. The whole story behind blind adaptive equalizers/blind deconvolution

    CERN Document Server

    Pinchas, Monika

    2012-01-01

    This e-book covers a variety of blind deconvolution/equalization methods based on both cost functions and Bayes rules where simulation results are supplied to support the theory - including Maximum Entropy density approximation technique and the Edgeworth Expansion approach used in various blind equalizers.

  10. POSTERIOR SEGMENT CAUSES OF BLINDNESS AMONG CHILDREN IN BLIND SCHOOLS

    Directory of Open Access Journals (Sweden)

    Sandhya

    2015-09-01

    Full Text Available BACKGROUND: It is estimated that there are 1.4 million irreversibly blind children in the world out of which 1 million are in Asia alone. India has the highest number of blind children than any other country. Nearly 70% of the childhood blindness is avoidable. There i s paucity of data available on the causes of childhood blindness. This study focuses on the posterior segment causes of blindness among children attending blind schools in 3 adjacent districts of Andhra Pradesh. MATERIAL & METHODS: This is a cross sectiona l study conducted among 204 blind children aged 6 - 16 years age. Detailed eye examination was done by the same investigator to avoid bias. Posterior segment examination was done using a direct and/or indirect ophthalmoscope after dilating pupil wherever nec essary. The standard WHO/PBL for blindness and low vision examination protocol was used to categorize the causes of blindness. A major anatomical site and underlying cause was selected for each child. The study was carried out during July 2014 to June 2015 . The results were analyzed using MS excel software and Epi - info 7 software version statistical software. RESULTS: Majority of the children was found to be aged 13 - 16 years (45.1% and males (63.7%. Family history of blindness was noted in 26.0% and consa nguinity was reported in 29.9% cases. A majority of them were belonged to fulfill WHO grade of blindness (73.0% and in majority of the cases, the onset of blindness was since birth (83.7%. The etiology of blindness was unknown in majority of cases (57.4% while hereditary causes constituted 25.4% cases. Posterior segment causes were responsible in 33.3% cases with retina being the most commonly involved anatomical site (19.1% followed by optic nerve (14.2%. CONCLUSIONS: There is a need for mandatory oph thalmic evaluation, refraction and assessment of low vision prior to admission into blind schools with periodic evaluation every 2 - 3 years

  11. Influence of Dry Soil on the Ability of Formosan Subterranean Termites, Coptotermes formosanus, to Locate Food Sources

    OpenAIRE

    Mary L. Cornelius; Weste L.A. Osbrink

    2011-01-01

    The effect of barriers of dry soil on the ability of Formosan subterranean termites, Coptotermes formosanus Shiraki (Isoptera: Rhinotermitidae), to construct tunnels and find food was evaluated. Termite movement and wood consumption in a three—chambered apparatus were compared between treatments with dry soil in the center container and treatments where the soil in the center container was moist. When a wood block was located in the release container, termites fed significantly more on that b...

  12. A review of the microgastropod genus Systenostoma Bavay & Dautzenberg, 1908 and a new subterranean species from China (Gastropoda, Pulmonata, Hypselostomatidae)

    OpenAIRE

    Adrienne Jochum; Rajko Slapnik; Marian Kampschulte; Gunhild Martels; Markus Heneka; Barna Pall-Gergely

    2014-01-01

    A review of the microgastropod genus Systenostoma is provided. Thai and Malaysian species are transferred to a new genus, Angustopila (type species: Systenostoma tamlod Panha & Burch 1999). A new subterranean Angustopila species is described here. Conchologically, the new species is most similar to the cave-dwelling, Thai A. tamlod (Panha & Burch, 1999). One Thai species (Systenostoma edentata) is transferred to the genus Hypselostoma. Vietnamese members remain in the genus Tonkinospi...

  13. Individual Behavior of Workers of the Formosan Subterranean Termite (Isoptera: Rhinotermitidae on Consecutive Days of Tunnel Construction

    Directory of Open Access Journals (Sweden)

    Mary L. Cornelius

    2012-03-01

    Full Text Available This study examines the individual behavior of workers of the Formosan subterranean termite, Coptotermes formosanus Shirkai, on two consecutive days of tunnel construction. In each trial, a group of 30 termite workers was observed continuously during the first 60 min of construction of a new tunnel on two consecutive days. On each day, an average of 68% of individuals did not participate in tunnel construction, 19% spent

  14. Perceptions & use of termite resistant treated wood products. Part I: The perspective of homeowners in Formosan subterranean termite infected States

    Directory of Open Access Journals (Sweden)

    Richard Vlosky

    2009-09-01

    Full Text Available Formosan subterranean termites (Coptotermes formosanus Shiraki, is estimated to cause hundreds of millions of dollars in losses annually in North America. Unlike most subterranean species, Formosan termites often build nests (cartons in living trees and wooden buildings, and even penetrate plaster, plastic, asphalt, mortar, creosote, concrete, and rubber to reach wood. The study addresses issues that U.S. home owners consider in evaluating whether to buy or build homes that are built with termite resistant building materials. The sample frame for this study consisted of a random sample of 5.000 home owners in the region where Formosan subterranean termites are a current or potential problem. When examined by state, 50 percent of respondents in Hawaii said termites have damaged the home they currently live in followed by respondents from Louisiana and California. On average, respondents indicated that preservative pressure treated wood and regular fumigation as being most effective in protecting a house against termites and only 8 percent of respondents said they would not pay a premium for a guaranteed termite-free new home.

  15. Overview on Deaf-Blindness

    Science.gov (United States)

    Miles, Barbara

    2008-01-01

    It may seem that deaf-blindness refers to a total inability to see or hear. However, in reality deaf-blindness is a condition in which the combination of hearing and visual losses in children cause "such severe communication and other develop mental and educational needs that they cannot be accommodated in special education programs solely for…

  16. Mole (Nevus)

    Science.gov (United States)

    ... melanoma). Remember the ABCDEs of melanoma lesions: A - Asymmetry: One half of the lesion does not mirror ... McGraw-Hill, 2003. Last Updated: 23 Jul 2010 Information for other ages: Child Teen Table of Contents: ...

  17. Blind Known Interference Cancellation

    CERN Document Server

    Zhang, Shengli; Wang, Hui

    2011-01-01

    This paper investigates interference-cancellation schemes at the receiver, in which the original data of the interference is known a priori. Such a priori knowledge is common in wireless relay networks. For example, a transmitting relay could be relaying data that was previously transmitted by a node, in which case the interference received by the node now is actually self information. Besides the case of self information, the node could also have overheard or received the interference data in a prior transmission by another node. Directly removing the known interference requires accurate estimate of the interference channel, which may be difficult in many situations. In this paper, we propose a novel scheme, Blind Known Interference Cancellation (BKIC), to cancel known interference without interference channel information. BKIC consists of two steps. The first step combines adjacent symbols to cancel the interference, exploiting the fact that the channel coefficients are almost the same between successive sy...

  18. GESTATIONAL TROPHOBLASTIC DISEASE: A PROSPECTIVE STUDY OF 82 CASES AND UTILITY OF P57 IMMUNOHISTOCHEMISTRY IN DIFFERENTIATING COMPLETE AND PARTIAL MOLE

    Directory of Open Access Journals (Sweden)

    Surya Babu

    2014-12-01

    Full Text Available BACKGROUND AND PURPOSE: Gestational trophoblastic disease (GTD is a common spectrum of abnormal placental villous trophoblastic proliferation that occurs in women of reproductive age group. The present study is undertaken to discuss about the epidemiology, clinical presentation and pathology diagnosis of each of the trophoblastic disease variants. MATERIALS AND METHODS: The present study included 82 cases of GTD over a period of 3 years. The H&E sections of FFPE tissue were studied. Periodic acid Schiff (PAS stain was done as an adjuvant in 5 cases of early complete mole. IHC with p57kip2 was done in 6 cases of complete mole and 6 cases of partial mole. RESULTS: Hydatidiform mole (93.9% was the most common variant of GTD with peak incidence in 21-30 years age group and more common in primigravida. There were one case of invasive mole, 2 cases of choriocarcinoma and 2 cases of persistent trophoblastic disease. Most patients of GTD were of blood group O followed by group A. Early complete mole, complete mole and partial mole were differentiated by examining H&E sections. Myxoid stroma of early complete mole showed PAS positivity. p57 was negative in all the 6 cases of complete mole. Five cases of partial mole showed positivity, but one case was negative; on review, it was diagnosed as complete mole.CONCLUSION: The study shows the high incidence of molar pregnancies in Indian women and discusses the importance and utility of IHC in hydatidiform mole pathology.

  19. Seasonal changes in burrow geometry of the common mole rat (Rodentia: Bathyergidae)

    Science.gov (United States)

    Thomas, H. G.; Scantlebury, M.; Swanepoel, D.; Bateman, P. W.; Bennett, N. C.

    2013-11-01

    Sociality in mole rats has been suggested to have evolved as a response to the widely dispersed food resources and the limited burrowing opportunities that result from sporadic rainfall events. In the most arid regions, individual foraging efficiency is reduced, and energetic constraints increase. In this study, we investigate seasonal differences in burrow architecture of the social Cryptomys hottentotus hottentotus in a mesic region. We describe burrow geometry in response to seasonal weather conditions for two seasons (wet and dry). Interactions occurred between seasons and colony size for the size of the burrow systems, but not the shape of the burrow systems. The fractal dimension values of the burrow systems did not differ between seasons. Thus, the burrow complexity was dependent upon the number of mole rats present in the social group.

  20. Effects of ultraviolet radiation on mole rats kidney: A histopathologic and ultrastructural study

    Directory of Open Access Journals (Sweden)

    Hüseyin Türker

    2014-04-01

    Full Text Available The purpose of this study was to realize the ultrastructural effects of ultraviolet radiation on the kidney tissue cells of mole rats (Spalax leucodon. The mole rats of 180–200 g body weight were divided into the control and radiation-trial groups. The control group was not given any radiation. The other groups were irradiated with artificially produced UVC radiation for 14, 28 and 60 days. The kidney tissue samples were prepared at the end of experiments and analyzed by the light and electron microscope. Several effects were observed in the kidney tissues cells analyzed in accordance with the dose magnitude of radiation. These results clearly show the detrimental effects of UVC radiation on kidney tissue cells in exposure periods dependent on radiation dose and exposure time.

  1. Twin pregnancy with complete hydatidiform mole and coexisting live fetus complicated with HELLP syndrome

    Directory of Open Access Journals (Sweden)

    Deepti Sharma

    2013-02-01

    Full Text Available Hydatidiform mole with a coexisting live twin is an extremely rare event. It poses a great challenge for the obstetrician to decide for or against continuation of such a pregnancy, especially if the conception is after infertility treatment. Continuation carries risk of medical complications and persistent trophoblastic disease. We report a case of 22 year old primigravida, with complete hydatidiform mole coexisting with a live fetus. Patient had conceived in her fourth cycle of ovulation induction and wanted to continue pregnancy. She developed severe preeclampsia and HELLP syndrome. In this case report we highlight the importance of intense antenatal monitoring and the possibility of sudden deterioration of maternal condition forcing immediate termination. [Int J Reprod Contracept Obstet Gynecol 2013; 2(1.000: 92-94

  2. Analysis of internal doses to Mole voles inhabiting the East-Ural radioactive trace

    Energy Technology Data Exchange (ETDEWEB)

    Malinovsky, G.; Yarmoshenko, I. [Institute of Industrial Ecology UB RAS (Russian Federation); Chibiryak, M.; Vasil' ev, A. [Institute of Plant and Animal Ecology UB RAS (Russian Federation)

    2014-07-01

    Substantial task of development of approaches to radiation protection of non-human biota is investigation of relationships of exposure to dose, and dose to effects. Small mammals inhabiting territory of the East-Ural Radioactive Trace (EURT) are affected to ionizing radiation for many generations after accident at Mayak plutonium production in 1957. According to results of numerous studies a number of effects of exposure are observed. It is remarkable that the revealed effects are both negative and adaptive. In particular, the analysis of the variability of morphological structures of the axial skull and lower jaw in the population of northern mole vole (Ellobius talpinus Pall.), the burrowing rodent inhabiting the EURT, is of great interest. At the same time there is no reliable assessment of the radiation doses to these animals. Earlier we developed the approach to assess internal doses to mouse-like rodents (mice and voles) caused by incorporated {sup 90}Sr, which is the main dose contributing radionuclide at the EURT. Dose assessments are based on the results of beta-radiometry of intact bone. Routine methods for measuring the activity concentration of {sup 90}Sr in skeleton require ashing of samples, however in morphometric studies the destruction of material should be avoided: the skulls of mole voles are stored in the environmental samples depository of IPAE. Coefficients linking results of beta-radiometry of intact bone and activity concentration of {sup 90}Sr in skull of mouse was obtained basing on comparison of results of beta-radiometry of intact bone and bone ash. Obtained coefficients cannot be directly applied for calculating activity concentration of {sup 90}Sr in mole vole skulls because they are significantly larger. Therefore the additional study is required to assess proper coefficient of conversion from beta-radiometry to activity concentration of {sup 90}Sr. Developed dose assessment procedure includes application of the published values of

  3. Mechanical Performance of Rat, Mouse and Mole Spring Traps, and Possible Implications for Welfare Performance

    OpenAIRE

    Baker, Sandra E.; Ellwood, Stephen A.; Tagarielli, Vito L.; Macdonald, David W.

    2012-01-01

    Lethal spring traps are widely used for killing small mammals in the UK. Many require government approval, based primarily on humaneness. However, mole traps and break-back traps for rats and mice are exempt; those available vary widely in price and apparent quality. The EU is considering implementing a Trapping Directive that would alter UK legislation, and a recent report advised the EU that trapping legislation should cover all trapped species and encourage improvement of traps. Mechanical...

  4. On the Mole-Rat (Cryptomys Hottentotus Damarensis (Rodentia in the Kalahari Gemsbok National Park

    Directory of Open Access Journals (Sweden)

    G de Graaff

    1972-01-01

    Full Text Available Aspects of the ecology and distribution of the Damara mole-rat (Cryptomys hottentotus damarensis are discussed relative to its life in the arid Kalahari Gemsbok National Park. The value of coat colour as a taxonomic criterion for the subspecies is discussed. Notes are also presented on reproduction, aspects of behaviour such as: habitat, nests, orientation, activity, locomotion, voice, food, feeding and social life, symbiosis, commensalism, parasites and predators.

  5. The reproductive biology of the Mashona mole - rat (\\kur{Fukomys darlingi}) from southern Malawi.

    OpenAIRE

    JERKOVIČOVÁ, Diana

    2010-01-01

    The population of the social Mashona mole - rat (Fukomys darlingi) from southern Malawi differs from the population from Zimbabwe in many aspects of its biology. In this study I have found remarkable differences also in the reproductive biology of these two populations. The most signifiant distinctions are double lenght of gestation and litters with more and larger pups in Malawian population. The analysis of reproductive and ecological parameters in bathyergids did not showed obvious differe...

  6. The sense of touch in the star-nosed mole: from mechanoreceptors to the brain

    OpenAIRE

    Kenneth C. Catania

    2011-01-01

    Star-nosed moles are somatosensory specialists that explore their environment with 22 appendages that ring their nostrils. The appendages are covered with sensory domes called Eimer's organs. Each organ is associated with a Merkel cell–neurite complex, a lamellated corpuscle, and a series of 5–10 free nerve endings that form a circle of terminal swellings. Anatomy and electrophysiological recordings suggest that Eimer's organs detect small shapes and textures. There are parallels between the ...

  7. Cutaneous and periodontal inputs to the cerebellum of the naked mole-rat (Heterocephalus glaber

    Directory of Open Access Journals (Sweden)

    Diana K Sarko

    2013-11-01

    Full Text Available The naked mole-rat (Heterocephalus glaber is a small fossorial rodent with specialized dentition that is reflected by the large cortical area dedicated to representation of the prominent incisors. Due to naked mole-rats’ behavioral reliance on the incisors for digging and for manipulating objects, as well as their ability to move the lower incisors independently, we hypothesized that expanded somatosensory representations of the incisors would be present within the cerebellum in order to accommodate a greater degree of proprioceptive, cutaneous, and periodontal input. Multiunit electrophysiological recordings targeting the ansiform lobule were used to investigate tactile inputs from receptive fields on the entire body with a focus on the incisors. Similar to other rodents, a fractured somatotopy appeared to be present with discrete representations of the same receptive fields repeated within each folium of the cerebellum. These findings confirm the presence of somatosensory inputs to a large area of the naked mole-rat cerebellum with particularly extensive representations of the lower incisors and mystacial vibrissae. We speculate that these extensive inputs facilitate processing of tactile cues as part of a sensorimotor integration network that optimizes how sensory stimuli are acquired through active exploration and in turn adjusts motor outputs (such as independent movement of the lower incisors. These results highlight the diverse sensory specializations and corresponding brain organizational schemes that have evolved in different mammals to facilitate exploration of and interaction with their environment.

  8. Egg donor pregnancy: a potential pitfall in DNA genotyping diagnosis of hydatidiform moles.

    Science.gov (United States)

    Buza, Natalia; Hui, Pei

    2014-09-01

    A 34-yr-old woman presented with missed abortion at 10 wk of estimated clinical gestational age and underwent dilation and curettage. Gross and microscopic evaluation of the uterine contents revealed the presence of mildly hydropic, dysmorphic chorionic villi, with occasional trophoblastic pseudo-inclusions. The morphologic features raised the suspicion for partial hydatidiform mole, and DNA genotyping was performed using the AmpFlSTR Identifiler PCR Amplification system. The chorionic villous tissue showed unique alleles - not present in the maternal decidual tissue - at 12 of the 15 short tandem repeat loci, and 8 loci showed 2 unique alleles, suggesting a diandric, paternal-only genome. In contrast, p57 immunohistochemistry demonstrated a normal staining pattern with positive nuclear staining in villous stromal cells and cytotrophoblasts. Review of the patient's medical records revealed that the pregnancy was conceived through in vitro fertilization with egg donor embryos, explaining the presence of unexpected alleles simulating a dispermic complete mole on DNA genotyping. This is the first case report illustrating that an egg donor pregnancy may mimic a complete hydatidiform mole on DNA genotyping. PMID:25083967

  9. Structural, magnetic and microwave properties of barium hexaferrite thick films with different Fe/Ba mole ratio

    Energy Technology Data Exchange (ETDEWEB)

    Verma, Samiksha [School of Physics and Materials Science, Thapar University, Patiala 147004 (India); Dhawan, S.K. [Polymeric & Soft Materials Section, National Physical laboratory, New Delhi 119912 (India); Paesano, Andrea [Departamento de Fisica, Universidade Estadual de Maringá, Av. Colombo 5790, Maringá (Brazil); Pandey, O.P. [School of Physics and Materials Science, Thapar University, Patiala 147004 (India); Sharma, Puneet, E-mail: puneet.sharma@thapar.edu [School of Physics and Materials Science, Thapar University, Patiala 147004 (India)

    2015-12-15

    Barium hexaferrite (BaFe{sub 12}O{sub 19}) thick films (∼60 µm) with different BaO·xFe{sub 2}O{sub 3} mole ratio (x=5.0–6.0) were prepared by screen printing method. X-ray diffraction analysis confirmed the formation of single phase BaFe{sub 12}O{sub 19} (BaM). Preferential site occupation of Fe{sup 3+} ion at five different crystallographic sites, with varied mole ratio was measured by Mössbauer spectroscopy. Vacancy fraction found to be higher at 4f{sub 1}, 4f{sub 2} and 2b sites for mole ratio 5.5 and 5.0 respectively. Magnetic measurement shows that the magnetization (M) and magnetocrystalline anisotropy field (H{sub a}) depends upon mole ratio. M and H{sub a} are found to be maximum for mole ratio 5.5, while the coercivity (H{sub c}) remains constant. Reflection losses (R{sub L}) in the frequency range of 12–18 GHz were also studied. Present investigation demonstrates the effect of mole ratio on structural, magnetic and microwave absorption properties of BaM thick films for microwave device applications. - Highlights: • Single phase BaM thick films with different Fe/Ba mole ratio are prepared. • Site preference of Fe ion is estimated by Mössbauer spectroscopy. • Magnetization and magnetocrystalline ansisotropy is found maximum for 5.5 mole ratio. • Absorption frequency found to vary with the mole ratio.

  10. Effects of Gypsophila saponins on bacterial growth kinetics and on selection of subterranean clover rhizosphere bacteria.

    Science.gov (United States)

    Fons, F; Amellal, N; Leyval, C; Saint-Martin, N; Henry, M

    2003-06-01

    Plant secondary metabolites, such as saponins, have a considerable impact in agriculture because of their allelopathic effects. They also affect the growth of soil microorganisms, especially fungi. We investigated the influence of saponins on rhizosphere bacteria in vitro and in soil conditions. The effects of gypsophila saponins on the growth kinetics of rhizosphere bacteria were studied by monitoring the absorbance of the cultures in microtiter plates. Gypsophila saponins (1%) increased the lag phase of bacterial growth. The impact of gypsophila saponins on subterranean clover rhizosphere was also investigated in a pot experiment. The addition of gypsophila saponins did not modify clover biomass but significantly increased (twofold with 1% saponins) the weight of adhering soil. The number of culturable heterotrophic bacteria of the clover rhizosphere was not affected by the addition of gypsophila saponins. Nevertheless, the phenotypical characterization of the dominant Gram-negative strains of the clover rhizosphere, using the Biolog system, showed qualitative and quantitative differences induced by 1% saponins. With the addition of saponins, the populations of Chryseomonas spp. and Acinetobacter spp., the two dominant culturable genera of control clover, were no longer detectable or were significantly decreased, while that of Aquaspirillum dispar increased and Aquaspirillum spp. became the major genus. Aquaspirillum dispar and Aquaspirillum spp. were also the dominant rhizosphere bacteria of Gypsophila paniculata, which greatly accumulates these saponins in its roots. These results suggest that saponins may control rhizosphere bacteria in soil through rhizodeposition mechanisms. PMID:14569290

  11. Changes in methylation during progressive transcriptional silencing in transgenic subterranean clover.

    Science.gov (United States)

    Hagan, Nicholas D; Spencer, Donald; Moore, Andrew E; Higgins, Thomas J V

    2003-11-01

    A transgenic line of subterranean clover (Trifolium subterraneum) containing a gene for a sulphur-rich sunflower seed albumin (ssa gene) and a gene conferring tolerance to the herbicide phosphinothricin (bar gene) was previously shown to stably express these genes as far as the T3 generation. In subsequent generations there was a progressive decline in the level of expression of both of these genes such that, by the T7 generation, the plants were almost completely susceptible to the herbicide and the mean level of sunflower seed albumin was reduced to 10-30% of the level in the T2 and T3 generations. The decline in SSA protein correlated closely with a decline in the level of ssa RNA. In vitro transcription experiments with nuclei isolated from plants of the early and late generations showed that the reduced mRNA level was associated with a reduced level of transcription of the ssa transgene. Transcription of the bar transgene was also reduced in the late generations. Bisulphite sequencing analysis showed that the decline in expression of the ssa gene between T3 and subsequent generations correlated closely with increased CpG methylation in the promoter, but not in the coding region. Analysis of the bar gene promoter showed that high levels of CpG methylation preceded the first detectable decline in expression of the bar gene by one generation, suggesting that methylation was not the direct cause of transgene silencing in these plants. PMID:17134405

  12. Postecdysis Sclerotization of Mouthparts of the Formosan Subterranean Termites (Isoptera: Rhinotermitidae).

    Science.gov (United States)

    Kakkar, Garima; Chouvenc, Thomas; Su, Nan-Yao

    2016-04-01

    In termites, it is challenging to recognize the incidence of molting in workers because of their successive stationary molt, asynchronous molting among individuals, cryptic behavior, a soft and poorly sclerotized cuticle, and they immediately consume the shed exuvia of nestmates. This study describes a method in which the degree of sclerotization of the mouthparts in newly molted workers of the Formosan subterranean termite can be quantified and used to determine if an individual has recently molted, within a 36-h time frame. Changes in the tanning of mouthparts over time were used as a measure of the index of sclerotization in workers postmolting. Upon ecdysis, the primary point of articulation of the mandible already initiated sclerotization, which may allow the movement of the mandibles during the shedding of the exuvium. The sclerotization of the secondary point of articulation and the mandibular teeth, and the width of sclerotization of the mandibles, progressively increased until reaching a plateau around 36-h postecdysis, which imply that workers can regain some level of activity as early as 2 d after ecdysis. Our observations allowed for the determination of variables for the sclerotization of the mouthparts to easily identify workers that recently molted, and this method will be useful in future studies that focus on the molting activity of workers over time and space within a termite colony, in the scope of improving current control strategies for termite pests. PMID:26743216

  13. Radiosensitivity of subterranean bacteria in the Hungarian upper permian siltstone formation

    International Nuclear Information System (INIS)

    The main purpose of this work was to study the radioresistance of subterranean aerobic and anaerobic isolates from the Hungarian Upper Permian Siltstone (Aleurolite) Formation, in order to assess the safety of potential sites of future underground repositories for nuclear waste. A total of 93 isolates were studied. The radiosensitivities of these aerobic and anaerobic bacteria isolates were determined: the D10 values (decimal reducing doses) of the aerobic spore-formers lay in the range 0.80-2.44 kGy, and those of the anaerobic spore-formers lay in the range 1.86-4.93 kGy. The D10 values of the aerobic and anaerobic vegetative isolates were much lower, in the ranges 0.11-0.57 and 0.22-0.40 kGy, respectively. The variability in bacterial radioresistance indicates the biodiversity at this potential disposal site. These results can affect the construction of a future underground repository, since knowledge of the most resistant microorganism may be of importance as concerns calculation of the time required to inactivate the bacteria surrounding the containers

  14. Investigations of subterranean microorganisms. Their importance for performance assessment of radioactive waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Pedersen, K. [Goeteborg Univ. (Sweden). General and Marine Microbiology; Karlsson, Fred [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden)

    1995-06-01

    This report presents a broad and thorough description of how microorganisms may influence safety of repositories for radioactive waste. First, an overview of the Swedish concepts for disposal is given, including a discussion of the geological, chemical and hydrological conditions in repositories. Then the limiting and stimulating factors for life of microorganisms are reviewed, such as relations to oxygen, temperature, pH, radiation, pressure, water and nutrients availability. Bacteria in the cycles of carbon, nitrogen, sulfur, iron, manganese and hydrogen are also discussed. A literature review of subterranean bacteria is given in chapter 4. Chapter 5 treats investigations of microorganisms in repository-like environments, and microbial corrosion and redox processes relevant for materials in the repository and for the mobility of radionuclides. Possibilities to predict the activity and presence of microorganisms through mathematical models are discussed in chapter 6. Chapter 7 summarizes the conclusion drawn in the report, how microorganisms may influence performance safety assessment of radioactive waste disposal, and also identifies research needs. 293 refs, 43 figs, 36 tabs.

  15. Investigations of subterranean microorganisms. Their importance for performance assessment of radioactive waste disposal

    International Nuclear Information System (INIS)

    This report presents a broad and thorough description of how microorganisms may influence safety of repositories for radioactive waste. First, an overview of the Swedish concepts for disposal is given, including a discussion of the geological, chemical and hydrological conditions in repositories. Then the limiting and stimulating factors for life of microorganisms are reviewed, such as relations to oxygen, temperature, pH, radiation, pressure, water and nutrients availability. Bacteria in the cycles of carbon, nitrogen, sulfur, iron, manganese and hydrogen are also discussed. A literature review of subterranean bacteria is given in chapter 4. Chapter 5 treats investigations of microorganisms in repository-like environments, and microbial corrosion and redox processes relevant for materials in the repository and for the mobility of radionuclides. Possibilities to predict the activity and presence of microorganisms through mathematical models are discussed in chapter 6. Chapter 7 summarizes the conclusion drawn in the report, how microorganisms may influence performance safety assessment of radioactive waste disposal, and also identifies research needs. 293 refs, 43 figs, 36 tabs

  16. Laboratory Techniques for the Blind

    Science.gov (United States)

    Tombaugh, Dorothy

    1972-01-01

    Describes modifications of laboratory procedures for the BSCS Green Version biology, including dissection, microbiology, animal behavior, physiology, biochemistry, and genetics that make the methods suitable for direct experimentation by blind students. Discusses models as substitutes for microscopy. (AL)

  17. Student Art for Blind Children.

    Science.gov (United States)

    Vanda, Kay

    1982-01-01

    Describes a project in which high school student volunteers designed art activities for blind children. Students incorporated the sensation of motion and texture into their designs for toys, puzzles, games, and story illustrations. (AM)

  18. Blinded trials taken to the test

    DEFF Research Database (Denmark)

    Hróbjartsson, A; Forfang, E; Haahr, M T;

    2007-01-01

    Blinding can reduce bias in randomized clinical trials, but blinding procedures may be unsuccessful. Our aim was to assess how often randomized clinical trials test the success of blinding, the methods involved and how often blinding is reported as being successful....

  19. What It's Like to Be Color Blind

    Science.gov (United States)

    ... Homework? Here's Help White House Lunch Recipes What It's Like to Be Color Blind KidsHealth > For Kids > What It's Like to Be Color Blind Print A A ... blind. But some people really are color blind. It doesn't mean they can't see any ...

  20. Clinical Usefulness of Immunohistochemical Staining of p57kip2 for the Differential Diagnosis of Complete Mole

    OpenAIRE

    Shigeru Sasaki; Yasushi Sasaki; Toshiaki Kunimura; Akihiko Sekizawa; Yoshihiro Kojima; Koichi Iino

    2015-01-01

    Objective. Can polymer-based immunohistochemical staining of p57kip2 replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion? Methods and Materials. Original paraffin-embedded tissue blocks from 14 equivocal cases were turned over to our laboratory and examined by immunohistochemical staining of p57kip2. Results. Four of the 14 cases showed clearly negative nuclear staining in cytotrophoblasts and villous stromal cells: these result...

  1. Attenuation of arsenic in a karst subterranean stream and correlation with geochemical factors: a case study at Lihu, South China.

    Science.gov (United States)

    Zhang, Liankai; Yang, Hui; Tang, Jiansheng; Qin, Xiaoqun; Yu, Au Yik

    2014-11-01

    Arsenic (As) pollutants generated by human activities in karst areas flow into subterranean streams and contaminate groundwater easily because of the unique hydrogeological characteristics of karst areas. To elucidate the reaction mechanisms of arsenic in karst subterranean streams, physical-chemical analysis was conducted by an inductively coupled plasma mass spectrometer and an X-ray fluorescence spectrometer. The results show that inorganic species account for most of the total arsenic, whereas organic arsenic is not detected or occurs in infinitesimal amounts. As(III) accounts for 51.0%±9.9% of the total inorganic arsenic. Arsenic attenuation occurs and the attenuation rates of total As, As(III) and As(V) in the Lihu subterranean stream are 51%, 36% and 59%, respectively. To fully explain the main geochemical factors influencing arsenic attenuation, SPSS 13.0 and CANOCO 4.5 bundled with CanoDraw for Windows were used for simple statistical analysis and redundancy analysis (RDA). Eight main factors, i.e., sediment iron (SFe), sediment aluminum (SAl), sediment calcium (SCa), sediment organic matter (SOM), sediment manganese (SMn), water calcium (WCa(2+)), water magnesium (WMg(2+)), and water bicarbonate ion (WHCO3(-)) were extracted from thirteen indicators. Their impacts on arsenic content rank as: SFe>SCa>WCa(2+)>SAl>WHCO3(-)>SMn>SOM>WMg(2+). Of these factors, SFe, SAl, SCa, SOM, SMn, WMg(2+) and WCa(2+) promote arsenic attenuation, whereas WHCO3(-) inhibits it. Further investigation revealed that the redox potential (Eh) and pH are adverse to arsenic removal. The dramatic distinction between karst and non-karst terrain is that calcium and bicarbonate are the primary factors influencing arsenic migration in karst areas due to the high calcium concentration and alkalinity of karst water. PMID:25458676

  2. Subterranean ants (Hymenoptera, Formicidae as prey of fossorial reptiles (Reptilia, Squamata: Amphisbaenidae in Central Brazil

    Directory of Open Access Journals (Sweden)

    Flávia de Araújo Esteves

    2008-01-01

    Full Text Available The ant diversity observed in stomach contents of fossorial reptiles was compared to the subterranean ant richness collected using traditional and modern techniques of ant collections. We analyzed the alimentary tract of 64 specimens of amphisbaenians (4 Amphisbaena alba, 10 A. fuliginosa, 25 A. vermicularis, and 25 Leposternon infraorbitale collected during the fauna rescue for the construction of Serra da Mesa hydroelectric dam in the Tocantins River (from 1992 to 1997, in Minaçu County, Goiás, Brazil. We found only five ant species present in the stomach contents, all belonging to the army ants subfamily Ecitoninae. In contrast, the traditional techniques for subterranean ants' collection are far more efficient than the exam of fossorial reptile's stomach contents, collecting a much richer and diverse ant fauna. The exclusive occurrence of army ants in the alimentary tract of these fossorial reptiles suggests that they trace the chemical trails laid by the ants while moving inside and over the soil. Further, the occurrence of the epigaeic army ants Eciton and Labidus in the stomach contents suggests that amphisbaenians may forage on the soil surface as well.A diversidade de formigas no conteúdo estomacal de répteis fossoriais foi comparada à riqueza de formigas subterrâneas coletadas com o uso de técnicas tradicionais e modernas para sua coleta. Analisamos o trato alimentar de 64 espécimes de anfisbenídeos (4 Amphisbaena alba, 10 A. fuliginosa, 25 A. vermicularis e 25 Leposternon infraorbitale coletados durante o resgate da fauna para a construção da represa da Hidroelétrica da Serra da Mesa no Rio Tocantins (de 1992 a 1997, na cidade de Minaçu, Goiás, Brasil. Encontramos apenas cinco espécies de formigas presentes nos conteúdos estomacais aqui examinados, todas pertencentes à subfamília das formigas-de-correição, Ecitoninae. Ao contrário, as técnicas tradicionais de coleta de formigas subterrâneas são muito mais

  3. Multidimensional MRI-CT atlas of the naked mole-rat brain

    Directory of Open Access Journals (Sweden)

    Fumiko Seki

    2013-12-01

    Full Text Available Naked mole-rats have a variety of distinctive features such as the organisation of a hierarchical society (known as eusociality, extraordinary longevity, and cancer resistance; thus, it would be worthwhile investigating these animals in detail. One important task is the preparation of a brain atlas database that provide comprehensive information containing multidimensional data with various image contrasts, which can be achievable using a magnetic resonance imaging (MRI. Advanced MRI techniques such as diffusion tensor imaging (DTI, which generates high contrast images of fibre structures, can characterise unique morphological properties in addition to conventional MRI. To obtain high spatial resolution images, MR histology, DTI, and X-ray computed tomography (CT were performed on the fixed adult brain. Skull and brain structures were segmented as well as reconstructed in stereotaxic coordinates. Data were also acquired for the neonatal brain to allow developmental changes to be observed. Moreover, in vivo imaging of naked mole-rats was established as an evaluation tool of live animals. The data obtained comprised three-dimensional (3D images with high tissue contrast as well as stereotaxic coordinates. Developmental differences in the visual system were highlighted in particular by DTI. Although it was difficult to delineate optic nerves in the mature adult brain, parts of them could be distinguished in the immature neonatal brain. From observation of cortical thickness, possibility of high somatosensory system development replaced to the visual system was indicated. 3D visualisation of brain structures in the atlas as well as the establishment of in vivo imaging would promote neuroimaging researches towards detection of novel characteristics of eusocial naked mole-rats.

  4. Subterranean termites (Isoptera: Rhinotermitidae):Exploitation of equivalent food resources with different forms of placement

    Institute of Scientific and Technical Information of China (English)

    Juliana Toledo Lima; Ana Maria Costa-Leonardo

    2012-01-01

    Coptotermes gestroi and Heterotermes tenuis have been described as important urban pests in Brazil.The establishment of control technologies using baits that consider the social behavior of termites requires a better knowledge of their foraging behavior.Thus,this study analyzed the feeding behavior of these species with three different forms of food placement:food on the surface of a substrate and food either partially or completely buried in the substrate.Experimental arenas were composed of a central chamber connected to three food chambers.Each central chamber contained 550 foragers of C.gestroi or 517 foragers ofH.tenuis.Blocks ofPinus elliottii were placed in the different food chambers.After 28 days,the consumption of each wood block and the percentage of foraging individuals recruited for food chambers were verified in relation to the total survival rate obtained for each one of the 20 replicates.Results showed that completely buried food was most consumed for H.tenuis and presented a higher recruitment rate of workers and soldiers for both species.Although the consumption had non-significant differences for C.gestroi,these termites exhibited a tendency to prefer completely buried food.In these conditions,it can be concluded that the forms of food placement used in the present research influenced the recruitment of individuals for both species.Data also suggests that when the foraging subterranean termites find food resources in the tunneling substrate,they tend to concentrate their efforts on it,a behavior regime that reduces exposure to external environment.

  5. Subterranean ventilation: a key but poorly known process affecting the carbon balance of semi-arid ecosystems

    Science.gov (United States)

    López Ballesteros, Ana; Sánchez Cañete, Enrique P.; Serrano Ortiz, Penélope; Kowalski, Andrew S.; Oyonarte, Cecilio; Domingo, Francisco

    2016-04-01

    Subterranean ventilation, conceived as the advective transport of CO2-rich air from the vadose zone to the atmosphere through a porous media (i.e. soil or snow; Sánchez-Cañete et al., 2013), has arisen as an important process contributing to the carbon (C) balance of Mediterranean ecosystems (Kowalski et al., 2008; Sánchez-Cañete et al., 2011; Serrano-Ortiz et al., 2014), apart from other well-known biotic processes (i.e. plant photosynthesis, autotrophic and heterotrophic respiration). Recent studies have linked this subterranean CO2 release to fluctuations in the friction velocity or wind speed under drought conditions when water-free soil pores enable air transport (Rey et al., 2012a, 2013), however, barometric pressure variations has been suggested as another important driver (Sánchez-Cañete et al., 2013). In this study, we investigate this process in newly studied semi-arid grassland located in SE Spain, as the ideal ecosystem to do so given the great length of the dry season and the slight biotic activity limited to the winter season. Preliminary results, based on unpublished analyzed eddy covariance data and subterranean CO2 molar fraction measurements, confirm the presence of ventilation events from May to October for seven years 2009-2015. During these events, increases in the friction velocity correlates with sizeable CO2 emissions of up to ca.10 μmol m‑2 s‑1, and CO2 molar fraction regularly drops 2000-3000 ppm just after the turbulence peak, at several depths below the soil surface (0.15 and 1.5 m). Additionally, during the driest period (July-August), the friction velocity explains from 37% to 57% of the net C emission variability. On the other hand, the model residuals do not show a significant relationship, neither with air pressure nor with soil water content. Overall, the results found in this newly monitored site demonstrate, as shown by past research, the relevance of subterranean ventilation as a key process in the C balance of

  6. The effect of carbon mole ratio on the fabrication of silicon carbide

    OpenAIRE

    Sutham Niyomwas

    2008-01-01

    Silicon Carbide (SiC) particles were synthesized by self-propagating high temperature synthesis (SHS) from a powder mixture of SiO2-C-Mg. The reaction was carried out in a SHS reactor under static argon gas at a pressure of 0.5 MPa. The standard Gibbs energy minimization method was used to calculate the equilibrium composition of the reacting species. The effects of carbon mole ratio on the precursor mixture (C/SiO2/Mg: 1/1/2 to 3/1/2) and on the SiC conversion were investigated using X-ray d...

  7. [Fourth part of:] Gibraltar from end of Old [mistitled] Mole. c.1880

    OpenAIRE

    Unknown

    2003-01-01

    Second part of a panoramic view composed of 5 joined prints, cloth-backed. The panorama shows a view looking towards the south part of the town from the New Mole. At the right of the photograph ships and hulks are moored at the dockyard with the town beyond. Among the prominent buildings identifiable are the South Barracks behind the town, the Barrack Chapel directly in front, and the Station Hospital on the skyline at the right of the picture. The panorama follows the sea wall and the Ro...

  8. [Third part of:] Gibraltar from end of Old [mistitled] Mole. c.1880

    OpenAIRE

    Unknown

    2003-01-01

    Second part of a panoramic view composed of 5 joined prints, cloth-backed. The panorama shows a view looking towards the south part of the town from the New Mole. At the right of the photograph ships and hulks are moored at the dockyard with the town beyond. Among the prominent buildings identifiable are the South Barracks behind the town, the Barrack Chapel directly in front, and the Station Hospital on the skyline at the right of the picture. The panorama follows the sea wall and the Ro...

  9. [Second part of:] Gibraltar from end of Old [mistitled] Mole. c.1880

    OpenAIRE

    Unknown

    2003-01-01

    Second part of a panoramic view composed of 5 joined prints, cloth-backed. The panorama shows a view looking towards the south part of the town from the New Mole. At the right of the photograph ships and hulks are moored at the dockyard with the town beyond. Among the prominent buildings identifiable are the South Barracks behind the town, the Barrack Chapel directly in front, and the Station Hospital on the skyline at the right of the picture. The panorama follows the sea wall and the Ro...

  10. [First part of:] Gibraltar from end of Old [mistitled] Mole. circa 1880

    OpenAIRE

    Unknown

    2003-01-01

    First part of a panoramic view composed of 5 joined prints, cloth-backed. The panorama shows a view looking towards the south part of the town from the New Mole. At the right of the photograph ships and hulks are moored at the dockyard with the town beyond. Among the prominent buildings identifiable are the South Barracks behind the town, the Barrack Chapel directly in front, and the Station Hospital on the skyline at the right of the picture. The panorama follows the sea wall and the Ros...

  11. [Fifth part of:] Gibraltar from end of Old [mistitled] Mole. c.1880

    OpenAIRE

    Unknown

    2003-01-01

    Second part of a panoramic view composed of 5 joined prints, cloth-backed. The panorama shows a view looking towards the south part of the town from the New Mole. At the right of the photograph ships and hulks are moored at the dockyard with the town beyond. Among the prominent buildings identifiable are the South Barracks behind the town, the Barrack Chapel directly in front, and the Station Hospital on the skyline at the right of the picture. The panorama follows the sea wall and the Ro...

  12. Ultrasound imaging of partial hydatidiform mole in the second trimester of pregnancy

    International Nuclear Information System (INIS)

    The case report of a 27 year-old patient with 18 weeks gestation, admitted to the Obstetrics Department of 'Mariana Grajales Coello' Provincial Gynecology and Obstetrics Hospital of Santiago de Cuba due to high blood pressure, cephalea and pain in lower abdomen is described. Additional tests confirmed a partial hydatidiform mole, so that uterine curettage was performed and small fragments of endometrial stroma were removed for pathological study. Outpatient medical monitoring was recommended and the patient had an appointment at 21 days for controlling and evaluating her general state

  13. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    OpenAIRE

    Rella, C. W.; H Chen; A. E. Andrews; A. Filges; C. Gerbig; Hatakka, J.; A. Karion; N. L. Miles; Richardson, S. J.; M. Steinbacher; C. Sweeney; Wastine, B.; Zellweger, C.

    2012-01-01

    Traditional techniques for measuring the mole fractions of greenhouse gas in the well-mixed atmosphere have required extremely dry sample gas streams (dew point < −25 °C) to achieve the inter-laboratory compatibility goals set forth by the Global Atmospheric Watch program of the World Meteorological Organization (WMO/GAW) for carbon dioxide (±0.1 ppm) and methane (±2 ppb). Drying the sample gas to low levels of water vapor can be expensive, time-consuming, and/or problematic, especial...

  14. 20 CFR 416.983 - How we evaluate statutory blindness.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How we evaluate statutory blindness. 416.983... AGED, BLIND, AND DISABLED Determining Disability and Blindness Blindness § 416.983 How we evaluate statutory blindness. We will find that you are blind if you are statutorily blind within the meaning...

  15. 20 CFR 416.982 - Blindness under a State plan.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Blindness under a State plan. 416.982 Section..., BLIND, AND DISABLED Determining Disability and Blindness Blindness § 416.982 Blindness under a State... plan because of your blindness for the month of December 1973; and (c) You continue to be blind...

  16. Access to Mathematics by Blind Students: A Global Problem

    OpenAIRE

    Arthur I. Karshmer; Daryoush D. Farsi

    2007-01-01

    The issue of blindness and legally blind is becoming a global issue. Based on the last statistics from American Foundation for the blind, there are approximately 10 million blind and visually impaired people in the United States alone. Over 45 million people around the world are completely blind. 180 million more people are legally blind, and approximately 7 million people are diagnosed as blind or legally blind every year. One of the greatest stumbling blocks in the ability of the blind to e...

  17. Estimation of alkali metal mole percent and weight of calcined solids for ICPP calcine

    International Nuclear Information System (INIS)

    An updated method is given for estimation of the weight of calcined solids and volume reduction factor for calcine, and mole percent sodium plus potassium in calcine produced from radioactive waste in a fluidized-bed calciner at the Idaho Chemical Processing Plant (ICPP). It incorporates new information on a calcine chemistry from a study by K. N. Brewer and G. F. Kessinger in which they determined the compounds formed during calcination by both high temperature thermodynamic equilibrium calculations and by analyses of pilot-plant calcines. An explanation of the assumptions made in the calculations, along with several example calculations and comparisons with the previous calculation methods are included. This method allows calculation of the heat generation rate and sodium content of the calcine, which are used to determine the suitability of the calcine for storage in the ICPP bin sets. Although this method accurately predicts the weight of calcine and mole percent Na + K for its intended purpose, the compounds predicted should only be used as a first approximation for other purposes since the calculation does not incorporate all of the compounds, such as mixed-metal oxides, which may form during calcination

  18. Resonant Spin-Flavor Conversion of Supernova Neutrinos: Dependence on Electron Mole Fraction

    CERN Document Server

    Yoshida, T; Kimura, K; Yokomakura, H; Kawagoe, S; Kajino, T

    2009-01-01

    Detailed dependence of resonant spin-flavor (RSF) conversion of supernova neutrinos on electron mole fraction Ye is investigated. Supernova explosion forms a hot-bubble and neutrino-driven wind region of which electron mole fraction exceeds 0.5 in several seconds after the core collapse. When a higher resonance of the RSF conversion is located in the innermost region, flavor change of the neutrinos strongly depends on the sign of 1-2Ye. At an adiabatic high RSF resonance the flavor conversion of bar{nu}_e -> nu_{mu,tau} occurs in Ye 0.5 and inverted mass hierarchy. In other cases of Ye values and mass hierarchies, the conversion of nu_e -> bar{nu}_{mu,tau} occurs. The final bar{nu}_e spectrum is evaluated in the cases of Ye 0.5 taking account of the RSF conversion. Based on the obtained result, time variation of the event number ratios of low bar{nu}_e energy to high bar{nu}_e energy is discussed. In normal mass hierarchy, an enhancement of the event ratio should be seen in the period when the electron frac...

  19. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    Directory of Open Access Journals (Sweden)

    C. W. Rella

    2013-03-01

    Full Text Available Traditional techniques for measuring the mole fractions of greenhouse gases in the well-mixed atmosphere have required dry sample gas streams (dew point inter-laboratory compatibility goals (WMO, 2011a without drying the sample gas. In this paper, we present laboratory methodology for empirically deriving the water vapour correction factors, and we summarise a series of in-situ validation experiments comparing the measurements in humid gas streams to well-characterised dry-gas measurements. By using the manufacturer-supplied correction factors, the dry-mole fraction measurements have been demonstrated to be well within the GAW compatibility goals up to a water vapour concentration of at least 1%. By determining the correction factors for individual instruments once at the start of life, this water vapour concentration range can be extended to at least 2% over the life of the instrument, and if the correction factors are determined periodically over time, the evidence suggests that this range can be extended up to and even above 4% water vapour concentrations.

  20. Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P

    Directory of Open Access Journals (Sweden)

    Lewin Gary R

    2010-05-01

    Full Text Available Abstract Recent research has proposed a pathway in which sensory neurons expressing the capsaicin activated ion channel TRPV1 are required for histamine-induced itch and subsequent scratching behavior. We examined histamine-induced itch in the African naked mole-rat (Heterocephalus glaber and found that although naked mole-rats display innate scratching behavior, histamine was unable to evoke increased scratching as is observed in most mouse strains. Using calcium imaging, we examined the histamine sensitivity of naked mole-rat dorsal root ganglia (DRG neurons and identified a population of small diameter neurons activated by histamine, the majority of which are also capsaicin-sensitive. This suggested that naked mole-rat sensory neurons are activated by histamine, but that spinal dorsal horn processing of sensory information is not the same as in other rodents. We have previously shown that naked mole-rats naturally lack substance P (SP in cutaneous C-fibers, but that the neurokinin-1 receptor is expressed in the superficial spinal cord. This led us to investigate if SP deficiency plays a role in the lack of histamine-induced scratching in this species. After intrathecal administration of SP into the spinal cord we observed robust scratching behavior in response to histamine injection. Our data therefore support a model in which TRPV1-expressing sensory neurons are important for histamine-induced itch. In addition, we demonstrate a requirement for active, SP-induced post-synaptic drive to enable histamine sensitive afferents to drive itch-related behavior in the naked mole-rat. These results illustrate that it is altered dorsal horn connectivity of nociceptors that underlies the lack of itch and pain-related behavior in the naked mole-rat.

  1. [Aiming for zero blindness].

    Science.gov (United States)

    Nakazawa, Toru

    2015-03-01

    Glaucoma is the leading cause of acquired blindness in Japan. One reason that it often leads to blindness is that it can continue to worsen even after effective medical reduction of intraocular pressure (IOP), the only evidence-based treatment. The limitations of current treatments make it critical to identify IOP-independent factors that can cause glaucoma and develop new drugs to target these factors. This is a challenging task, as the pathology of glaucoma is thought to be very complex, with different combinations of factors underlying its development and progression in different patients. Additionally, there is a deficiency in methods to efficiently perform clinical evaluations and reliably probe the state of the disease over relatively short periods. In addition, newly developed drugs need to be evaluated with clinical trials, for which human and financial resources are limited, before they can be widely used for treatment. Taking all these issues into consideration, it is evident that there are two urgent issues to consider: the development of methods to classify glaucoma in detail based on its pathology, and the improvement of clinical evaluation methods. In this review, we discuss some of our efforts to develop new neuroprotective agents for glaucoma, with a focus on the following three areas: 1. Clinical research and development of methods to classify glaucoma in detail based on IOP-independent factors, and the exploration of possibilities for the improvement of clinical evaluation of glaucoma. 2. Pathology-based research and development of new drugs for glaucoma, focusing on comprehensive gene expression analysis and the development of molecule-targeting drugs, using murine optic nerve crush as a disease model. 3. Development of next generation in vivo imaging modalities and the establishment of infrastructure enabling "big-data" analysis. First, we discuss our clinical research and the development of methods to classify glaucoma in detail based on IOP

  2. New treatments of hereditary blindness

    DEFF Research Database (Denmark)

    Bertelsen, Mette; Rosenberg, Thomas; Larsen, Michael

    2013-01-01

    Ongoing clinical trials are targeting several previously intractable hereditary causes of blindness of congenital, childhood or early adulthood onset, mainly in the optic nerve and retina. The intended stage of initiation of the new therapeutic approaches ranges from neonatal life and a structura......Ongoing clinical trials are targeting several previously intractable hereditary causes of blindness of congenital, childhood or early adulthood onset, mainly in the optic nerve and retina. The intended stage of initiation of the new therapeutic approaches ranges from neonatal life and a...... structurally intact retinal tissue to adult life with a complete loss of photoreceptors. It must be assumed that some of the trials will succeed in producing new therapies and action must be taken to refine and accelerate diagnostics and to preserve therapeutic potential in blind people....

  3. Improved mortality of the Formosan subterranean termite by fungi, when amended with cuticle-degrading enzymes or eicosanoid biosynthesis inhibitors.

    Science.gov (United States)

    Wright, Maureen S; Lax, Alan R

    2016-01-01

    Formosan subterranean termites (FST) were exposed to strains of Beauveria pseudobassiana (Bpb) and Isaria fumosorosea (Ifr) to determine virulence of the fungi. Once lethality was determined, sublethal doses of Bpb were combined with enzymes capable of degrading the insect cuticle to measure the potential to enhance fungal infection. Bpb applied to FST in combination with proteinases and a chitinase caused increased mortality over the fungus alone. Mortality was enhanced when Ifr was applied to FST in combination with a chitinase isolated from Serratia marcesans. A lipase isolated from Pseudomonas cepacia, when combined with Ifr, also resulted in greater mortality than all control treatments. FST were also exposed to the eicosanoid biosynthesis inhibitors (EBIs) dexamethasone (DEX), ibuprofen (IBU), and ibuprofen sodium salt (IBUNA), in combination with Ifr. Combining Ifr with IBUNA caused significantly increased mortality on days 6, 7, and 9. Cuticle-degrading enzymes and EBIs may have potential to enhance the pathogenic effect of a fungal control agent against the Formosan subterranean termite. PMID:26122366

  4. PROXY BLIND SIGNATURE BASED ON ECDLP

    Directory of Open Access Journals (Sweden)

    SATARUPA PRADHAN,

    2011-03-01

    Full Text Available Proxy blind signature combines the properties of both proxy signature and blind signature. In a proxy signature scheme, a signer delegates his signing power to a proxy, who signs a message on behalf of the original signer. In a blind signature scheme, the signer cannot link the relationship between the blind message and the signature of the chosen message. Therefore, it is very suitable for electronic commerceapplication. In this paper, a proxy blind signature scheme based on ECDLP (Elliptic Curve Discrete Logarithm Problem has been proposed, which satisfy the security properties of both the blind signature and the proxy signature. Analysis shows that our scheme is secure and efficient.

  5. Night blindness and ancient remedy

    Directory of Open Access Journals (Sweden)

    H.A. Hajar Al Binali

    2014-01-01

    Full Text Available The aim of this article is to briefly review the history of night blindness and its treatment from ancient times until the present. The old Egyptians, the Babylonians, the Greeks and the Arabs used animal liver for treatment and successfully cured the disease. The author had the opportunity to observe the application of the old remedy to a patient. Now we know what the ancients did not know, that night blindness is caused by Vitamin A deficiency and the animal liver is the store house for Vitamin A.

  6. [The punishment of blinding and the life of the blind].

    Science.gov (United States)

    Büttner, Jan Ulrich

    2009-01-01

    The article deals with a group of people who were deprived of their eyesight by private acts of force or by executions of lawful sentences. In early medieval texts blinding is frequently mentioned in connection with popes, kings, princes or bishops. However, since the High Middle Ages these dignitaries were increasingly spared the loss of their eyes. It may be said that on the whole, from the eighth to the twelfth century, blinding was overwhelmingly used to dispose of political adversaries, but did then rapidly turn into a criminal punishment. In the earliest 'Landfriedensordnungen' of the late eleventh century, the loss of the perpetrator's eyes crops up as punishment for breach of the peace, while later it was applied to a variety of more or less serious offences. The destiny of the blinded in the early Middle Ages is only highlighted by sketches of a few individual cases; for the High and late Middle Ages--apart from a few notable exceptions--it is only possible to reflect on the general situation of blind people in society, since the sources usually do not differentiate between those having lost their sight through human violence or due to other causes. PMID:20506724

  7. Effect of Naphthalene, Butylated Hydroxytoluene, Dioctyl Phthalate, and Adipic Dioctyl Ester, Chemicals Found in the Nests of the Formosan Subterranean Termite (Isoptera: Rhinotermitidae) on a Saprophytic Mucor sp.

    Science.gov (United States)

    Fungi are commonly found associated with termites and their nests. Four chemicals that have been isolated from the nests of the Formosan subterranean termite, Coptotermes formosanus Shiraki, were evaluated to determine their effect on a common nest fungus, a saprophytic Mucor sp. Butylated hydroxyto...

  8. Aggregation and feeding behavior of the formosan subterranean termite (Isoptera: Rhinotermitidae) on wood decayed by three species of wood rot fungi

    Science.gov (United States)

    Aggregation and feeding behavior of the Formosan subterranean termite, Coptotermes formosanus Shiraki, was evaluated on wood decayed by three species of fungus that use different enzymatic pathways to degrade lignocellulose, the brown rot fungus, Gloeophyllum trabeum and two white rot fungi, Phanero...

  9. [Characteristics and Transport Patterns of Ammonia, Nitrites, Nitrates and Inorganic Nitrogen Flux at Epikarst Springs and a Subterranean Stream in Nanshan, Chongqing].

    Science.gov (United States)

    Zhang, Yuan-zhu; He, Qiu-fang; Jiang, Yong-jun; Li, Yong

    2016-04-15

    In a karst groundwater system, it develops complex multiple flows because of its special geological structure and unique physical patterns of aquifers. In order to investigate the characteristics and transport patterns of ammonia, nitrite and nitrate in epikarst water and subterranean stream, the water samples were collected monthly in a fast-urbanizing karst region. The results showed distinctive characteristics of three forms of inorganic nitrogen. The concentration of inorganic nitrogen was stable in the epikarst water while it was fluctuant in the subterranean stream. Epikarst water was less affected by rainfall and sewage compared with subterranean stream. In epikarst water, the nitrate concentration was much higher than the ammonia concentration. Dissolved inorganic nitrogen, mainly from non-point source pollution related to agricultural activities, passed in and out of the epikarst water based on a series of physical; chemical and biological processes in the epikarst zone, such as ammonification, adsorption and nitrification. On the contrary, subterranean stream showed a result of NH₄⁺-N > NO₃⁻-N in dry seasons and NO₃⁻-N > NH₄⁺-N in rainy seasons. This can be due to the fact that sanitary and industrial sewage flowed into subterranean river through sinkholes, fissures and grikes in dry season. Dissolved inorganic nitrogen in subterranean river was mainly from the non-point source pollution in wet season. Non-point source pollutants entered into subterranean water by two transport ways, one by penetration along with vadose flow through fissures and grikes, and the other by conduit flow through sinkholes from the surface runoff, soil water flow and epikarst flow. The export flux of DIN was 56.05 kg · (hm² · a)⁻¹, and NH₄⁺-N and NO₃⁻-N accounted for 46.03% and 52.51%, respectively. The contributions of point-source pollution and non point-source pollution to the export flux of DIN were 25.08% and 74.92%, respectively, based on run

  10. Estimating regional methane surface fluxes: the relative importance of surface and GOSAT mole fraction measurements

    Directory of Open Access Journals (Sweden)

    A. Fraser

    2013-06-01

    Full Text Available We use an ensemble Kalman filter (EnKF, together with the GEOS-Chem chemistry transport model, to estimate regional monthly methane (CH4 fluxes for the period June 2009–December 2010 using proxy dry-air column-averaged mole fractions of methane (XCH4 from GOSAT (Greenhouse gases Observing SATellite and/or NOAA ESRL (Earth System Research Laboratory and CSIRO GASLAB (Global Atmospheric Sampling Laboratory CH4 surface mole fraction measurements. Global posterior estimates using GOSAT and/or surface measurements are between 510–516 Tg yr−1, which is less than, though within the uncertainty of, the prior global flux of 529 ± 25 Tg yr−1. We find larger differences between regional prior and posterior fluxes, with the largest changes in monthly emissions (75 Tg yr−1 occurring in Temperate Eurasia. In non-boreal regions the error reductions for inversions using the GOSAT data are at least three times larger (up to 45% than if only surface data are assimilated, a reflection of the greater spatial coverage of GOSAT, with the two exceptions of latitudes >60° associated with a data filter and over Europe where the surface network adequately describes fluxes on our model spatial and temporal grid. We use CarbonTracker and GEOS-Chem XCO2 model output to investigate model error on quantifying proxy GOSAT XCH4 (involving model XCO2 and inferring methane flux estimates from surface mole fraction data and show similar resulting fluxes, with differences reflecting initial differences in the proxy value. Using a series of observing system simulation experiments (OSSEs we characterize the posterior flux error introduced by non-uniform atmospheric sampling by GOSAT. We show that clear-sky measurements can theoretically reproduce fluxes within 10% of true values, with the exception of tropical regions where, due to a large seasonal cycle in the number of measurements because of clouds and aerosols, fluxes are within 15% of true fluxes. We evaluate our

  11. Elliptic Curve Blind Digital Signature Schemes

    Institute of Scientific and Technical Information of China (English)

    YOULin; YANGYixian; WENQiaoyan

    2003-01-01

    Blind signature schemes are important cryptographic protocols in guaranteeing the privacy or anonymity of the users.Three new blind signature schemes and their corresponding generalizations are pro-posed. Moreover, their securities are simply analyzed.

  12. Blindness Biggest Fear for Many Americans

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_160254.html Blindness Biggest Fear for Many Americans Losing vision would ... 4, 2016 THURSDAY, Aug. 4, 2016 (HealthDay News) -- Blindness is what many Americans fear most, a new ...

  13. Blinding in randomized clinical trials: imposed impartiality

    DEFF Research Database (Denmark)

    Hróbjartsson, A; Boutron, I

    2011-01-01

    Blinding, or "masking," is a crucial method for reducing bias in randomized clinical trials. In this paper, we review important methodological aspects of blinding, emphasizing terminology, reporting, bias mechanisms, empirical evidence, and the risk of unblinding. Theoretical considerations and...

  14. Blinding in randomized clinical trials: imposed impartiality

    DEFF Research Database (Denmark)

    Hróbjartsson, A; Boutron, I

    2011-01-01

    Blinding, or "masking," is a crucial method for reducing bias in randomized clinical trials. In this paper, we review important methodological aspects of blinding, emphasizing terminology, reporting, bias mechanisms, empirical evidence, and the risk of unblinding. Theoretical considerations...

  15. The Concept and Operations of Blind Number

    Institute of Scientific and Technical Information of China (English)

    PANG Yan-jun; LIU Kai-di; ZHANG Bo-wen

    2001-01-01

    This paper gives the definition and operations of blind number, and discusses its operationproperties. Blind number is a mathematical tool to express and deal with complex information with severalkinds of uncertainty.

  16. Convolutive Blind Source Separation Methods

    DEFF Research Database (Denmark)

    Pedersen, Michael Syskind; Larsen, Jan; Kjems, Ulrik;

    2008-01-01

    During the past decades, much attention has been given to the separation of mixed sources, in particular for the blind case where both the sources and the mixing process are unknown and only recordings of the mixtures are available. In several situations it is desirable to recover all sources from...

  17. Metro Navigation for the Blind

    Science.gov (United States)

    Sanchez, Jaime; Saenz, Mauricio

    2010-01-01

    This study evaluates the impact of using the software program AudioMetro, a tool that supports the orientation and mobility of people who are blind in the Metro system of Santiago de Chile. A quasi-experimental study considering experimental and control groups and using the paired Student's t in a two sample test analysis (pretest-posttest) was…

  18. Overview on Deaf-Blindness

    Science.gov (United States)

    ... reading lip-reading speech Along with nonverbal and verbal conversations, a child who is deaf-blind needs a reliable routine of meaningful activities, and some way or ways that this routine can be communicated to her or him. Touch cues, gestures, and use of object symbols are some ...

  19. Visual Product Identification for Blind

    Directory of Open Access Journals (Sweden)

    Krutarth Majithia

    2015-12-01

    Full Text Available This project is developed to make the life of blind people easy. This is a camera based system to scan the barcode behind the image and read the description of the product with the help of Id stored in the barcode. This is very beneficial in case of finding out the description of packaged goods to the blind people and thus helping them in deciding to purchase a product or not especially which are packaged. This is because it becomes very difficult for the blind people to distinguish between the packaged goods. In order to use this system, all the user needs to do is capture the image on the product in the mobile phone which then resolves the barcode which means it scans the image to find out the Id stored. Thus this application really benefits blind and visually impaired people and thus making their work of identifying products easy. This is very easy to use and affordable as it requires a scanner to scan the barcode and a camera phone to take the picture of the image containing the barcode. This is now easy to implement as most of the mobile phones today have the required resolution in order to scan the barcode to identify the Id stored in it and read out the product description. This project can be implemented in any shopping mall, supermarket, Book stores, Medical stores etc.

  20. Vesicouterine fistula and blind vagina

    International Nuclear Information System (INIS)

    A case of vesicouterine fistula with blind vagina following cesarean section for obstructed labor is presented. It was surgically treated by fistulectomy, cervicoplasty and maintenance of bladder and cervical potency by catheterization. Intrauterine synechiae formation was prevented by copper T insertion and oral contraceptive pills. The patient is making uneventful a symptomatic progress planning to conceive. (author)

  1. Creating workshops for blind and visually impaired

    OpenAIRE

    Rot, Peter

    2013-01-01

    The thesis Načrtovanje projektnih delavnic za osebe s slepoto in slabovidnostjo discusses the planning stage and the performance of projects for blind and visually impaired adults. It points out the positive effects of those projects on the life of an individual. Adults and senior citizens who are not blind from birth often lack professional help which would enable their adaptation to the life of blind and visually impaired. The thesis concentrates on one of the ways of integrating blind and ...

  2. Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: report of a case.

    Science.gov (United States)

    Rachad, Myriam; Chaara, Hikmat; Zahra Fdili, Fatim; Bouguern, Hakima; Melhouf, Abdilah

    2011-01-01

    It is known that most cases of Ovarian Hyperstimulation Syndrome (OHSS) are associated with the therapies for ovulation induction. However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism or polycystic ovary syndrome. We report a case of severe OHSS in spontaneous pregnancy with invasive mole in a 34 years old woman. The clinical picture showed abdominal pain, massive ascites, nausea, dyspnea and amenorrhea. After imaging examinations and laboratory tests, the diagnosis was established. The patient was managed expectantly with no complications. Although spontaneous ovarian hyperstimulation is a rare entity, it is important that the physician recognizes this condition. Prompt diagnosis and successful management is likely to avoid serious complications, which may develop rapidly. PMID:22355432

  3. Ultrastructural effects of ultraviolet C radiation on the stratum basale of mole rats epidermis

    Directory of Open Access Journals (Sweden)

    Mustafa Yel

    2014-10-01

    Full Text Available The ultrastructure of the epidermis of mole rats (Spalax leucodon was studied after irradiation with ultraviolet (UV light (λmax = 254 nm; 0.00147 J cm−2 s−1; for periods of 52, 112 and 168 h by using transmission electron microscope (TEM. After irradiation, Vacuolation in cytoplasm and mitochondria, and wrinkled nucleus were found in the stratum basal cells. Also, pathological aggregations of tonofilaments are formed in the desmosomes in these cells. These findings clearly demonstrated the harmful effects of ultraviolet C radiation on the stratum basale. The degree of pathological changes occurred depending on exposure time and radiation dosage applied.

  4. The effect of carbon mole ratio on the fabrication of silicon carbide

    Directory of Open Access Journals (Sweden)

    Sutham Niyomwas

    2008-03-01

    Full Text Available Silicon Carbide (SiC particles were synthesized by self-propagating high temperature synthesis (SHS from a powder mixture of SiO2-C-Mg. The reaction was carried out in a SHS reactor under static argon gas at a pressure of 0.5 MPa. The standard Gibbs energy minimization method was used to calculate the equilibrium composition of the reacting species. The effects of carbon mole ratio on the precursor mixture (C/SiO2/Mg: 1/1/2 to 3/1/2 and on the SiC conversion were investigated using X-ray diffraction and scanning electron microscope technique. The as-synthesized products of SiC-MgO powders were leached with 0.1M HCl acid solution to obtain the SiC particles.

  5. Hyaluronan in cancer - from the naked mole rat to nanoparticle therapy.

    Science.gov (United States)

    Rankin, Kenneth S; Frankel, Daniel

    2016-05-01

    Hyaluronan, a glycosaminoglycan, abundant in the tumour microenvironment, is a key player in many processes associated with cancer. Recently the cancer resistance of the naked mole rat has been attributed to the presence of an ultra-high molecular weight form of this molecule. The physical properties of this multifunctional biopolymer have been extensively studied in the context of synovial joints. However, relatively little has been reported with regard to the soft matter properties of hyaluronan in relation to cancer. In this review we examine the role of hyaluronan in cancer, paying particular attention to its mechanical interactions with malignant cells and its soft matter properties. In addition we discuss the use of hyaluronan based gels to study cancer invasion as well as nanoparticle based strategies for disease treatment. PMID:27079782

  6. Psychomotor Development for the Deaf-Blind.

    Science.gov (United States)

    Sherrill, Claudine

    The stages of psychomotor development in deaf blind children and youth are reviewed, and educational principles to guide psychomotor development programs for the deaf blind are outlined. Etiological factors which contribute to the psychomotor development of deaf blind persons are discussed including nonambulation and sensory deprivation, heart…

  7. 45 CFR 233.70 - Blindness.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Blindness. 233.70 Section 233.70 Public Welfare... FINANCIAL ASSISTANCE PROGRAMS § 233.70 Blindness. (a) State plan requirements. A State plan under title X or XVI of the Social Security Act must: (1) Contain a definition of blindness in terms of...

  8. BLIND ADAPTIVE XPIC BASED ON HOS

    Institute of Scientific and Technical Information of China (English)

    Fu Haiyang; Yang Longxiang; Peng Jianglong

    2001-01-01

    This paper presents a new blind XPIC and a new adaptive blind deconvolutional algorithm based on HOS processing, which separates and equalizes the signals in real time. The simulation results demonstrate that the performance of the proposed adaptive blind algorithm,compared with the conventional algorithms, is outstanding with the feature of feasibility, stability and fast convergence rate.

  9. Resources for Visually Impaired or Blind Students.

    Science.gov (United States)

    Hart, Elizabeth

    2000-01-01

    Suggests resources for school librarians who need materials for visually impaired or blind students. Highlights include the National Library Service for the Blind and Physically Handicapped; Louis Database of Accessible Materials for People Who Are Blind or Visually Impaired; Braille books; large print books, audio books; assistive technology; and…

  10. National Center On Deaf-Blindness

    Science.gov (United States)

    ... Profile My Profile Help Logout Menu NCDB: National Center on Deaf-Blindness NCDB: National Center on Deaf-Blindness Help Login | Make a Profile ... Together for Families State Deaf-Blind Projects & Parent Center Collaborations New OHOA Modules Released! Modules 9-18. ‹ › ...

  11. Occupant satisfaction with two blind control strategies

    DEFF Research Database (Denmark)

    Karlsen, Line Røseth; Heiselberg, Per Kvols; Bryn, Ida

    2015-01-01

    Highlights •Occupant satisfaction with two blind control strategies has been studied. •Control based on cut-off position of slats was more popular than closed slats. •Results from the study are helpful in development of control strategies for blinds. •The results give indications of how blinds...

  12. Effect of Temperature and Mole Ratio on the Synthesis Yield of Rhenium-Tetrofosmin

    Directory of Open Access Journals (Sweden)

    Widyastuti

    2015-08-01

    Full Text Available Technetium-99m (99mTc tetrofosmin is widely used in nuclear medicine as a diagnostic agent for myocardial perfusion and as a tumor imaging agent. As a parenteral preparation it requires an evaluation of its pharmacokinetics and stability in-vivo. Since 99mTc has a short half-life and is only available in very low concentrations, it is impossible to characterize its chemical properties and presence in the body. Due to this reason, only technetium-99 (T1/2 = 5 × 105 years, which is available in macro quantities, or natural rhenium can be used for this purpose. In this study rhenium-188 (188Re tetrofosmin will be synthesized and applied, because non-radioactive Re can be easily obtained. Synthesis and radiochemical purity analysis of carrier-added 188Re-tetrofosmin were carried out as a model to study the in-vivo stability of technetium-99m tetrofosmin. Rhenium-188 was used as a tracer to identify the formation of rhenium tetrofosmin. Rhenium gluconate was synthesized first prior to the formation of rhenium tetrofosmin. The quality of labeling for both rhenium gluconate and rhenium tetrofosmin was analyzed using paper- and thin-layer chromatography, respectively. Rhenium gluconate can be synthesized with high labeling yield within 1 hour, whereas rhenium tetrofosmin was synthesized both in room temperature and in an elevated temperature with various tetrofosmin-to-rhenium mole ratios.The results showed that heating at 95oC led to a higher yield of more than 90% within 30 minutes. Rhenium tetrofosmin could be produced in high radiochemical purity using an excess of tetrofosmin with mole ratio of 2000. It is concluded that rhenium tetrofosmin could be synthesized through the formation of rhenium gluconate, and a higher yield could be obtained in a shorter time by heating process.

  13. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    Directory of Open Access Journals (Sweden)

    C. W. Rella

    2012-08-01

    Full Text Available Traditional techniques for measuring the mole fractions of greenhouse gas in the well-mixed atmosphere have required extremely dry sample gas streams (dew point < −25 °C to achieve the inter-laboratory compatibility goals set forth by the Global Atmospheric Watch program of the World Meteorological Organization (WMO/GAW for carbon dioxide (±0.1 ppm and methane (±2 ppb. Drying the sample gas to low levels of water vapor can be expensive, time-consuming, and/or problematic, especially at remote sites where access is difficult. Recent advances in optical measurement techniques, in particular Cavity Ring Down Spectroscopy (CRDS, have led to the development of highly stable and precise greenhouse gas analyzers capable of highly accurate measurements of carbon dioxide, methane, and water vapor. Unlike many older technologies, which can suffer from significant uncorrected interference from water vapor, these instruments permit for the first time accurate and precise greenhouse gas measurements that can meet the WMO/GAW inter-laboratory compatibility goals without drying the sample gas. In this paper, we present laboratory methodology for empirically deriving the water vapor correction factors, and we summarize a series of in-situ validation experiments comparing the measurements in humid gas streams to well-characterized dry-gas measurements. By using the manufacturer-supplied correction factors, the dry-mole fraction measurements have been demonstrated to be well within the GAW compatibility goals up to at least 1% water vapor. By determining the correction factors for individual instruments once at the start of life, this range can be extended to at least 2% over the life of the instrument, and if the correction factors are determined periodically over time, the evidence suggests that this range can be extended above 4%.

  14. Gis-approach for variability assessment of soil electric conductivity under pedoturbation activity of mole rat (Spalax microphthalmus

    Directory of Open Access Journals (Sweden)

    T. М. Konovalova

    2010-06-01

    Full Text Available The results of the investigation of the impact of the mole rat’s activity on soil electric conductivity have been presented. GIS-technology have been shown to be effective for assessment of the pedoturbation activity effect on the soil surface heterogeneity formation. Method of the one-dimension spatial coordinated array transformation into matrix form has been proposed for following multidimension statistic analysis application. The quantity estimation of the mole rats role in formation of the habitat nanorelief-level diversity has been obtained by means of indexes of the landscape complexity and diversity.

  15. Optimization of a solar-blind and middle infrared two-colour photodetector using GaN-based bulk material and quantum wells

    International Nuclear Information System (INIS)

    This paper calculates the wavelengths of the interband transitions as a function of the Al mole fraction of A1xGa1–xN bulk material. It is finds that when the Al mole fraction is between 0.456 and 0.639, the wavelengths correspond to the solar-blind (250 nm to 280 nm). The influence of the structure parameters of A1yGa1–yN/GaN quantum wells on the wavelength and absorption coefficient of intersubband transitions has been investigated by solving the Schrödinger and Poisson equations self-consistently. The A1 mole fraction of the A1yGa1–yN barrier changes from 0.30 to 0.46, meanwhile the width of the well changes from 2.9 nm to 2.2 nm, for maximal intersubband absorption in the window of the air (3 μm < λ < 5 μm). The absorption coefficient of the intersubband transition between the ground state and the first excited state decreases with the increase of the wavelength. The results are finally used to discuss the prospects of GaN-based bulk material and quantum wells for a solar-blind and middle infrared two-colour photodetector. (classical areas of phenomenology)

  16. From" Televised Blind Date” to" Televised Half-blind Wedding”

    Institute of Scientific and Technical Information of China (English)

    倪俊

    2001-01-01

    @@ A couple of weeks ago I happened to see on TV how American young men and women go out on "blind dates” , arranged by a television station. It is interesting to see how a young man and a young woman enjoy playing, dining or chatting with each other happily and naturally before a TV camera, even though they have never known or met with each other before. Yesterday evening one of the biggest national TV stations, FOX by name, made another bold try by broadcasting live a "half-blind wedding” to the whole country. It is such an original and also absurd idea that 1 think only American television-men can have figured it out and carried it out.

  17. From "Televised Blind Date" to "Televised Half-blind Wedding"

    Institute of Scientific and Technical Information of China (English)

    倪俊

    2001-01-01

    A couple of weeks ago I happened to see on TV how American young men and women go out on "blind dates", arranged by a television station, It is interesting to see bow a young man and a young woman enjoy playing, dining or chatting with each other happily and naturally before a TV camera, even though they have never known or met with each other before. Yesterday evening one of the biggest national TV stations, FOX by name, made another bold try by broadcasting live a "half-blind wedding" to the whole country. It is such an original and also absurd idea that I think only American television-men can have figured it out and carried it out. In the beginning, the directors of FOX put ads in newspapers, openly asking the public: "Who wants to marry a multi-millionaire?" It did not cost much time or

  18. Blindness and severe visual impairment in pupils at schools for the blind in Burundi

    OpenAIRE

    Patrick Ruhagaze; Kahaki Kimani Margaret Njuguna; Lévi Kandeke; Paul Courtright

    2013-01-01

    Purpose: To determine the causes of childhood blindness and severe visual impairment in pupils attending schools for the blind in Burundi in order to assist planning for services in the country. Materials and Methods: All pupils attending three schools for the blind in Burundi were examined. A modified WHO/PBL eye examination record form for children with blindness and low vision was used to record the findings. Data was analyzed for those who became blind or severely visually impaired be...

  19. Rapid Assessment of Avoidable Blindness in Western Rwanda: Blindness in a Postconflict Setting

    OpenAIRE

    Wanjiku Mathenge; John Nkurikiye; Hans Limburg; Hannah Kuper

    2007-01-01

    Editors' Summary Background. VISION 2020, a global initiative that aims to eliminate avoidable blindness, has estimated that 75% of blindness worldwide is treatable or preventable. The WHO estimates that in Africa, around 9% of adults aged over 50 are blind. Some data suggest that people living in regions affected by violent conflict are more likely to be blind than those living in unaffected regions. Currently no data exist on the likely prevalence of blindness in Rwanda, a central African c...

  20. Area-wide management of the Formosan subterranean termite in New Orleans' French Quarter

    International Nuclear Information System (INIS)

    Full text: The Formosan subterranean termite, Coptotermes formosanus Shiraki (FST), is an invasive species first introduced to mainland United States in shipping crates and packing material returning from the Pacific realm during World War II. All of the Hawaiian Islands are known to have had infestations since the beginning of the 20th century. Initially the termites were discovered only in coastal cities of the southeast United States. Largely through transportation of infested materials the termite is now known to infest eleven southern states and cause an estimated USD 1 billion in damage that includes cost of preventive and remedial treatments and damage repair. The termite also is known to infest living trees, including the majestic live oaks that line New Orleans' boulevards. Subsequent loss of these century-old trees because of the structural damage inflicted by the termites is aesthetically unacceptable and the cost is inestimable. Populations of the termite are estimated to have increased 35-fold in the French Quarter during the last decade of the twentieth century. Colonies of the FST may contain millions of individuals and the foraging range of a colony may exceed 100 meters in diameter. Thus a single colony may infest several buildings within one or more city blocks. The foraging territories of neighboring colonies make it possible for one structure to be infested by more than a single FST colony. Moreover, recent research has demonstrated that the foraging territory of one colony was rapidly taken over by a neighboring colony once it was eliminated. Traditional termite control practices used highly toxic chemicals that rapidly killed the insects, or were highly repellent to them. In both cases, such liquid chemical treatments surrounding a structure served to protect it but with no appreciable effect on the size of the termite population, since colonies would survive in nearby unprotected structures or trees. Common wall construction and other unique

  1. A review of the microgastropod genus Systenostoma Bavay & Dautzenberg, 1908 and a new subterranean species from China (Gastropoda, Pulmonata, Hypselostomatidae).

    Science.gov (United States)

    Jochum, Adrienne; Slapnik, Rajko; Kampschulte, Marian; Martels, Gunhild; Heneka, Markus; Páll-Gergely, Barna

    2014-01-01

    A review of the microgastropod genus Systenostoma is provided. Thai and Malaysian species are transferred to a new genus, Angustopila (type species: Systenostoma tamlod Panha & Burch, 1999). A new subterranean Angustopila species is described here. Conchologically, the new species is most similar to the cave-dwelling, Thai A. tamlod (Panha & Burch, 1999). One Thai species (Systenostoma edentata) is transferred to the genus Hypselostoma. Vietnamese members remain in the genus Tonkinospira (nomen novum) for Systenostoma Bavay & Dautzenberg, 1908 (non Systenostoma Marsson, 1887). A comprehensive map of former Systenostoma species is presented. SEM and NanoCT images, including a video of A. huoyani sp. n. internal shell morphology, provide novel perspectives of the shells of Angustopila and of the scarcely known Vietnamese Tonkinospira species. The biology of these snails is not yet known but collection localities suggest a troglophilic ecology. PMID:24899848

  2. A review of the microgastropod genus Systenostoma Bavay & Dautzenberg, 1908 and a new subterranean species from China (Gastropoda, Pulmonata, Hypselostomatidae

    Directory of Open Access Journals (Sweden)

    Adrienne Jochum

    2014-05-01

    Full Text Available A review of the microgastropod genus Systenostoma is provided. Thai and Malaysian species are transferred to a new genus, Angustopila (type species: Systenostoma tamlod Panha & Burch 1999. A new subterranean Angustopila species is described here. Conchologically, the new species is most similar to the cave-dwelling, Thai A. tamlod (Panha & Burch, 1999. One Thai species (Systenostoma edentata is transferred to the genus Hypselostoma. Vietnamese members remain in the genus Tonkinospira (nomen novum for Systenostoma Bavay & Dautzenberg 1908 (non Systenostoma Marsson 1887. A comprehensive map of former Systenostoma species is presented. SEM and NanoCT images, including a video of A. huoyani sp. n. internal shell morphology, provide novel perspectives of the shells of Angustopila and of the scarcely known Vietnamese Tonkinospira species. The biology of these snails is not yet known but collection localities suggest a troglophilic ecology.

  3. A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.

    Directory of Open Access Journals (Sweden)

    Horia Negulescu

    Full Text Available Coptotermes formosanus is an imported, subterranean termite species with the largest economic impact in the United States. The frontal glands of the soldier caste termites comprising one third of the body mass, contain a secretion expelled through a foramen in defense. The small molecule composition of the frontal gland secretion is well-characterized, but the proteins remain to be identified. Herein is reported the structure and function of one of several proteins found in the termite defense gland secretion. TFP4 is a 6.9 kDa, non-classical group 1 Kazal-type serine protease inhibitor with activity towards chymotrypsin and elastase, but not trypsin. The 3-dimensional solution structure of TFP4 was solved with nuclear magnetic resonance spectroscopy, and represents the first structure from the taxonomic family, Rhinotermitidae. Based on the structure of TFP4, the protease inhibitor active loop (Cys(8 to Cys(16 was identified.

  4. Debris jets in continental phreatomagmatic volcanoes: A field study of their subterranean deposits in the Coombs Hills vent complex, Antarctica

    Science.gov (United States)

    Ross, Pierre-Simon; White, James D. L.

    2006-01-01

    The Ferrar large igneous province of Antarctica contains significant mafic volcaniclastic deposits, some of which are interpreted to fill large vent complexes. Such a complex was re-examined at Coombs Hills to map individual steep-sided cross-cutting bodies in detail, and we found several contrasting types, two of which are interpreted to have filled subterranean passageways forcefully opened from below into existing, non-consolidated debris. These transient conduits were opened because of the propagation of debris jets - upward-moving streams of volcaniclastic debris, steam, magmatic gases +/- liquid water droplets - following explosive magma-aquifer interaction. Some debris jets probably remained wholly subterranean, whereas others made it to the surface, but the studied outcrops do not allow us to differentiate between these cases. The pipes filled with country rock-rich lapilli-tuff or tuff-breccia are interpreted to have formed following phreatomagmatic explosions occurring near the walls or floor of the vent complex, causing fragmentation of both magma and abundant country rock material. In contrast, some of the cross-cutting zones filled with basalt-rich tuff-breccia or lapilli-tuff could have been generated following explosions taking place within pre-existing basalt-bearing debris, well away from the complex walls or floor. We infer that once focused jets were formed, they did not incorporate significant amounts of existing debris while travelling through them; instead, incorporation of fragments from the granular host took place near explosion sites. Other basalt-rich tuff-breccia zones, accompanied by domains of in situ peperite and coherent basalt pods, are inferred to have originated by less violent processes.

  5. Deep-Subterranean Microbial Habitats in the Hishikari Epithermal Gold Mine: Active Thermophilic Microbial Communities and Endolithic Ancient Microbial Relicts.

    Science.gov (United States)

    Hirayama, H.; Takai, K.; Inagaki, F.; Horikoshi, K.

    2001-12-01

    Deep subterranean microbial community structures in an epithermal gold-silver deposit, Hishikari gold mine, southern part of Kyusyu Japan, were evaluated through the combined use of enrichment culture methods and culture-independent molecular surveys. The geologic setting of the Hishikari deposit is composed of three lithologies; basement oceanic sediments of the Cretaceous Shimanto Supergroup, Quaternary andesites, and auriferous quartz vein. We studied the drilled core rock of these, and the geothermal hot waters from the basement aquifers collected by means of the dewatering system located at the deepest level in the mining sites. Culture-independent molecular phylogenetic analyses of PCR-amplified ribosomal DNA (rDNA) recovered from drilled cores suggested that the deep-sea oceanic microbial communities were present as ancient indigenous relicts confined in the Shimanto basement. On the other hand, genetic signals of active thermophilic microbial communities, mainly consisting of thermophilic hydrogen-oxidizer within Aquificales, thermophilic methanotroph within g-Proteobacteria and yet-uncultivated bacterium OPB37 within b-Proteobacteria, were detected with these of oceanic relicts from the subterranean geothermal hot aquifers (temp. 70-100ºC). Successful cultivation and FISH analyses strongly supported that these thermophilic lithotrophic microorganisms could be exactly active and they grew using geochemically produced hydrogen and methane gasses as nutrients. Based on these results, the deep-subsurface biosphere occurring in the Hishikari epithermal gold mine was delineated as endolithic ancient microbial relicts and modern habitats raising active lithotrophic thermophiles associated with the geological and geochemical features of the epithermal gold deposit.

  6. The contamination impact of human exploration to a subterranean environment and the implications for further crewed space exploration

    Science.gov (United States)

    Leuko, Stefan; Rettberg, Petra; De Waele, Jo; Sanna, Laura; Koskinen, Kaisa

    2016-07-01

    The quest of exploring and looking for life in new places is a human desire since centuries. Nowadays, we are not only looking on planet Earth any more, but our endeavours focus on nearby planets in our solar system. It is therefore of great importance to preserve the extra-terrestrial environment and not to contaminate it with terrestrial / human associated bacteria. At this point in time we are not able to send crewed missions to other planets; however, analysing the impact of human exploration on environments is of great planetary protection concern. This can be achieved by obtaining samples from a subterranean environment, where only expert speleologists have access and the human impact is considered very low. For this study, astronauts participating in the 2014 ESA CAVES (Cooperative Adventure for Valuing and Exercising human behaviour and performance Skills) training course, obtained samples from deep within a subterranean environment and returned them to the laboratory for molecular microbial analysis. The diversity of the returned soil samples was analysed by molecular means such as clone library and next-generation sequencing (NGS). It was found that humans have an immense impact on the microbial diversity in the environment. Although the cave system is sparsely entered by humans, a high relative abundance of Staphylococcus spp. and Propionibacteria spp., organisms that are characteristic for human skin, have been recovered. Some samples even showed the presence of human gut associated methanogenic archaea, Methanomassiliicoccus spp. The obtained data from this investigation indicate that human exploration is strongly polluting an environment and may lead to false-positive sign of life on other planets. It is therefore imperative to increase our awareness to this problem as well as work towards new protocols to protect a pristine extraterrestrial environment during exploration.

  7. Dynamic Thermodynamics with Internal Energy, Volume, and Amount of Moles as States : Application to Liquefied Gas Tank

    NARCIS (Netherlands)

    Arendsen, A. R. J.; Versteeg, G. F.

    2009-01-01

    Dynamic models for process design, optimization, and control usually solve a set of heat and/or mass balances as a function of time and/or position in the process. To obtain more robust dynamic models and to minimize the amount of assumptions, internal energy, volume, and amount of moles are chosen

  8. Paternity and relatedness in the natural population of the solitary bythyergid, the silvery mole-rat Heliophobius argenteocinereus

    Czech Academy of Sciences Publication Activity Database

    Patzenhauerová, Hana; Bryja, Josef; Šumbera, R.

    2007-01-01

    Roč. 1, Supp. (2007), s. 144. ISSN 1825-5272. [European Congress of Mammalogy /5./. 21.09.2007-26.09.2007, Siena] Institutional research plan: CEZ:AV0Z60930519 Keywords : African mole-rats Subject RIV: EB - Genetics ; Molecular Biology

  9. Effect of mole (Talpaеuropаеa digging activity on soil microflora in case of soil cadmium pollution

    Directory of Open Access Journals (Sweden)

    O. Y. Pakhomov

    2006-01-01

    Full Text Available Influence of fossorial activity of European mole Talpa еuropаеа on number and distribution of soil microorganisms under conditions of cadmium pollution of the soil is characterized. Mammals’ fossorial activity is an important natural ecological factor that contributes to microflora rehabilitation and development under conditions of contamination.

  10. Phylogeny of species and cytotypes of mole rats (Spalacidae) in Turkey inferred from mitochondrial cytochrome b gene sequences

    Czech Academy of Sciences Publication Activity Database

    Kandemir, I.; Sozen, M.; Matur, F.; Kankilic, T.; Martínková, Natália; Colak, F.; Ozkurt, S. O.; Colak, E.

    Paris: Université P. et M. Curie, 2011. s. 5 [European Congress of Mammalogy /7./. 19.07.2011-23.07.2011, Paris] Institutional research plan: CEZ:AV0Z60930519 Keywords : mole rats * phylogeny * Turkey Subject RIV: EG - Zoology http://www.alphavisa.com/ecm2011/pdf/ECM2011-Abstract_Book.pdf

  11. Net subterranean estuarine export fluxes of dissolved inorganic C, N, P, Si, and total alkalinity into the Jiulong River estuary, China

    Science.gov (United States)

    Wang, Guizhi; Wang, Zhangyong; Zhai, Weidong; Moore, Willard S.; Li, Qing; Yan, Xiuli; Qi, Di; Jiang, Yuwu

    2015-01-01

    To evaluate geochemical impacts of the subterranean estuary (STE) on the Jiulong River estuary, China, we estimated seasonal fluxes of subterranean water discharge into the estuary based on the mass balance of radium isotopes and net subterranean export fluxes of dissolved inorganic C (DIC), N (DIN), Si (DSi), soluble reactive phosphorus (SRP), and total alkalinity (TA). Based on 226Ra data, the subterranean discharge (in 107 m3 d-1) was estimated to be 0.29-0.60 in the spring, 0.69-1.44 in the summer, 0.45-0.93 in the fall, and 0.26-0.54 in the winter. This was equivalent to 8-19% of the concomitant river discharge. The net spatially integrated material fluxes from the STE into the estuary were equivalent up to 45-110% of the concomitant riverine fluxes for DIC and TA, around 14-32% for DSi and 7-19% for DIN, and negligible for SRP. Paradoxically, the mixing lines along the salinity gradient revealed no apparent additions of these species. These additions are not revealed because the STE is a relatively small spatially-averaged source (at most 11% of the total input at steady state) that spreads throughout the estuary as a non-point source in contrast to the major point sources of the river and the ocean for the estuary and a true open ocean endmember is likely lacking. Greater water flushing in the summer might dilute the STE effect on the mixing lines even more. The great spatial variation in salinity in the estuary introduced the major uncertainty in our estimates of the flushing time, which further affected the estimate of the subterranean discharge and associated material fluxes. Additionally, the great spatial variation in the STE endmember caused the relatively large ranges in these flux estimates. Despite apparent conservative mixing of DIC, DIN, and DSi in estuaries, net subterranean exports must be taken into account in evaluating geochemical impacts of estuarine exports on shelf waters.

  12. HP3 on ExoMars - Cutting airbag cloths with the sharp tip of a mechanical mole

    Science.gov (United States)

    Krause, C.; Izzo, M.; Re, E.; Mehls, C.; Richter, L.; Coste, P.

    2009-04-01

    The HP3 - Heat Flow and Physical Properties Package - is planned to be one of the Humboldt lander-based instruments on the ESA ExoMars mission. HP3 will allow the measurement of the subsurface temperature gradient and physical as well as thermophysical properties of the subsurface regolith of Mars down to a depth of 5 meters. From these measurements, the planetary heat flux can be inferred. The HP³ instrument package consists of a mole trailing a package of thermal and electrical sensors into the regolith. Beside the payload elements Thermal Excitation and Measurement Suite and a Permittivity Probe the HP3 experiment includes sensors to detect the forward motion and the tilt of the HP3 payload compartment. The HP3 experiment will be integrated into the lander platform of the ExoMars mission. The original accommodation featured a deployment device or a robotic arm to place HP3 onto the soil outside the deflated lander airbags. To avoid adding such deployment devices, it was suggested that the HP3 mole should be capable of piercing the airbags under the lander. The ExoMars lander airbag is made of 4 Kevlar layers (2 abrasive and 2 bladders). A double fold of the airbag (a worst case) would represent a pile of 12 layers. An exploratory study has examined the possibility of piercing airbag cloths by adding sharp cutting blades on the tip of a penetrating mole. In the experimental setup representative layers were laid over a Mars soil simulant. Initial tests used a hammer-driven cutting tip and had moderate to poor results. More representative tests used a prototype of the HP3 mole and were fully successful: the default 4 layer configuration was pierced as well as the 12 layer configuration, the latter one within 3 hours and about 3000 mole strokes This improved behaviour is attributed to the use of representative test hardware where guidance and suppression of mole recoil were concerned. The presentation will provide an explanation of the technical requirements on

  13. Variation of CO2 mole fraction in the lower free troposphere, in the boundary layer and at the surface

    Directory of Open Access Journals (Sweden)

    J. Tarniewicz

    2012-05-01

    Full Text Available Eight years of occasional flask air sampling and 3 yr of frequent in situ measurements of carbon dioxide (CO2 vertical profiles on board of a small aircraft, over a tall tower greenhouse gases monitoring site in Hungary are used for the analysis of the variations of vertical profile of CO2 mole fraction. Using the airborne vertical profiles and the measurements along the 115 m tall tower it is shown that the measurements at the top of the tower estimate the mean boundary layer CO2 mole fraction during the mid-afternoon fairly well, with an underestimation of 0.27–0.85 μmol mol−1 in summer, and an overestimation of 0.66–1.83 μmol mol−1 in winter. The seasonal cycle of CO2 mole fraction is damped with elevation. While the amplitude of the seasonal cycle is 28.5 μmol mol−1 at 10 m above the ground, it is only 10.7 μmol mol−1 in the layer of 2500–3000 m corresponding to the lower free atmosphere above the well-mixed boundary layer. The maximum mole fraction in the layer of 2500–3000 m can be observed around 25 March on average, two weeks ahead of that of the marine boundary layer reference (GLOBALVIEW. By contrast, close to the ground, the maximum CO2 mole fraction is observed late December, early January. The specific seasonal behavior is attributed to the climatology of vertical mixing of the atmosphere in the Carpathian Basin.

  14. Antagonistic Coevolution Drives Whack-a-Mole Sensitivity in Gene Regulatory Networks.

    Directory of Open Access Journals (Sweden)

    Jeewoen Shin

    2015-10-01

    Full Text Available Robustness, defined as tolerance to perturbations such as mutations and environmental fluctuations, is pervasive in biological systems. However, robustness often coexists with its counterpart, evolvability--the ability of perturbations to generate new phenotypes. Previous models of gene regulatory network evolution have shown that robustness evolves under stabilizing selection, but it is unclear how robustness and evolvability will emerge in common coevolutionary scenarios. We consider a two-species model of coevolution involving one host and one parasite population. By using two interacting species, key model parameters that determine the fitness landscapes become emergent properties of the model, avoiding the need to impose these parameters externally. In our study, parasites are modeled on species such as cuckoos where mimicry of the host phenotype confers high fitness to the parasite but lower fitness to the host. Here, frequent phenotype changes are favored as each population continually adapts to the other population. Sensitivity evolves at the network level such that point mutations can induce large phenotype changes. Crucially, the sensitive points of the network are broadly distributed throughout the network and continually relocate. Each time sensitive points in the network are mutated, new ones appear to take their place. We have therefore named this phenomenon "whack-a-mole" sensitivity, after a popular fun park game. We predict that this type of sensitivity will evolve under conditions of strong directional selection, an observation that helps interpret existing experimental evidence, for example, during the emergence of bacterial antibiotic resistance.

  15. Influence of the mole penetrator on measurements of heat flow in lunar subsurface layers

    Science.gov (United States)

    Wawrzaszek, Roman; Drogosz, Michal; Seweryn, Karol; Banaszkiewicz, Marek; Grygorczuk, Jerzy

    Measuring the thermal gradient in subsurface layers is a basic method of determination the heat flux from the interior of a planetary body to its surface. In case of the Moon, such measurements complemented with the results of theoretical analysis and modeling can significantly improve our understanding of the thermal and geological evolution of the Moon. In practice, temperature gradient measurements are performed by at least two sensors located at different depths under the surface. These sensors will be attached to a penetrator [1] or to a cable pulled behind the penetrator. In both cases the object that carries the sensors, e.g. penetrator, perturb temperature measurements. In our study we analyze a case of two thermal sensors attached to the ends of 350mm long penetrator made of a composite material. In agreement with the studies of other authors we have found that the penetrator should be placed at the depth of 2-3 meters, where periodic changes of the temperature due to variation of solar flux at the surface are significantly smaller than the error of temperature measurement. The most important result of our analysis is to show how to deconvolve the real gradient of the temperature from the measurements perturbed by the penetrator body. In this way it will be possible to more accurately determine heat flux in the lunar regolith. [1] Grygorczuk J., Seweryn K., Wawrzaszek R., Banaszkiewicz M., Insertion of a Mole Pene-trator -Experimental Results, /39th Lunar and Planetary Science Conference /League City, Texas 2008

  16. Cryptic sex? Estimates of genome exchange in unisexual mole salamanders (Ambystoma sp.).

    Science.gov (United States)

    Gibbs, H Lisle; Denton, Robert D

    2016-06-01

    Cryptic sex has been argued to explain the exceptional longevity of certain parthenogenetic vertebrate lineages, yet direct measurements of genetic exchange between sexual and apparently parthenogenetic forms are rare. Female unisexual mole salamanders (Ambystoma sp.) are the oldest known unisexual vertebrate lineage (~5 million years), and one hypothesis for their persistence is that allopolyploid female unisexuals periodically exchange haploid genomes 'genome exchange' during gynogenetic reproduction with males from sympatric sexual species. We test this hypothesis by using genome-specific microsatellite DNA markers to estimate the rates of genome exchange between sexual males and unisexual females in two ponds in NE Ohio. We also test the prediction that levels of gene flow should be higher for 'sympatric' (sexual males present) genomes in unisexuals compared to 'allopatric' (sexual males absent) unisexual genomes. We used a model testing framework in the coalescent-based program MIGRATE-N to compare models where unidirectional gene flow is present and absent between sexual species and unisexuals. As predicted, our results show higher levels of gene flow between sexuals and sympatric unisexual genomes compared to lower (likely artefactual) levels of gene flow between sexuals and allopatric unisexual genomes. Our results provide direct evidence that genome exchange between sexual and unisexual Ambystoma occurs and demonstrate that the magnitude depends on which sexual species are present. The relatively high levels of gene flow suggest that unisexuals must be at a selective advantage over sexual forms so as to avoid extinction due to genetic swamping through genome exchange. PMID:27100619

  17. Large-Scale DNS of Gas-Solid Flow on Mole-8.5

    CERN Document Server

    Xiong, Qingang; Li, Bo; Xua, Ji; Fang, Xiaojian; Wang, Junwu; He, Xianfeng; Wang, Xiaowei; Wang, Limin; Ge, Wei; Li, Jinghai

    2010-01-01

    Direct numerical simulation (DNS) for gas-solid flow is implemented on a multi-scale supercomputing system, Mole-8.5, featuring massive parallel GPU-CPU hybrid computing, for which the lattice Boltzmann method (LBM) is deployed together with the immersed moving boundary (IMB) method and discrete element method (DEM). A two-dimensional suspension with about 1,166,400 75-micron solid particles distributed in an area of 11.5cm x46cm, and a three-dimensional suspension with 129,024 solid particles in a domain of 0.384cm x1.512cm x0.384cm are fully-resolved below particle scale and distinct multi-scale heterogeneity are observed. Almost 20-fold speedup is achieved on one Nvidia C2050 GPU over one core of Intel E5520 CPU in double precision, and nearly ideal scalability is maintained when using up to 672 GPUs. The simulations demonstrate that LB-IMB-DEM modeling with parallel GPU computing may suggest a promising approach for exploring the fundamental mechanisms and constitutive laws of complex gas-solid flow, whic...

  18. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats

    Science.gov (United States)

    Miyawaki, Shingo; Kawamura, Yoshimi; Oiwa, Yuki; Shimizu, Atsushi; Hachiya, Tsuyoshi; Bono, Hidemasa; Koya, Ikuko; Okada, Yohei; Kimura, Tokuhiro; Tsuchiya, Yoshihiro; Suzuki, Sadafumi; Onishi, Nobuyuki; Kuzumaki, Naoko; Matsuzaki, Yumi; Narita, Minoru; Ikeda, Eiji; Okanoya, Kazuo; Seino, Ken-ichiro; Saya, Hideyuki; Okano, Hideyuki; Miura, Kyoko

    2016-01-01

    The naked mole-rat (NMR, Heterocephalus glaber), which is the longest-lived rodent species, exhibits extraordinary resistance to cancer. Here we report that NMR somatic cells exhibit a unique tumour-suppressor response to reprogramming induction. In this study, we generate NMR-induced pluripotent stem cells (NMR-iPSCs) and find that NMR-iPSCs do not exhibit teratoma-forming tumorigenicity due to the species-specific activation of tumour-suppressor alternative reading frame (ARF) and a disruption mutation of the oncogene ES cell-expressed Ras (ERAS). The forced expression of Arf in mouse iPSCs markedly reduces tumorigenicity. Furthermore, we identify an NMR-specific tumour-suppression phenotype—ARF suppression-induced senescence (ASIS)—that may protect iPSCs and somatic cells from ARF suppression and, as a consequence, tumorigenicity. Thus, NMR-specific ARF regulation and the disruption of ERAS regulate tumour resistance in NMR-iPSCs. Our findings obtained from studies of NMR-iPSCs provide new insight into the mechanisms of tumorigenicity in iPSCs and cancer resistance in the NMR. PMID:27161380

  19. Functional characteristics of the naked mole rat μ-opioid receptor.

    Directory of Open Access Journals (Sweden)

    Melanie Busch-Dienstfertig

    Full Text Available While humans and most animals respond to µ-opioid receptor (MOR agonists with analgesia and decreased aggression, in the naked mole rat (NMR opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1 can underlie altered behavioral responses to opioids. Therefore, we hypothesized that the primary structure of the NMR MOR may differ from other species. Sequencing of the NMR oprm1 revealed strong homology to other mammals, but exposed three unique amino acids that might affect receptor-ligand interactions. The NMR and rat oprm1 sequences were cloned into mammalian expression vectors and transfected into HEK293 cells. Radioligand binding and 3'-5'-cyclic adenosine monophosphate (cAMP enzyme immunoassays were used to compare opioid binding and opioid-mediated cAMP inhibition. At normalized opioid receptor protein levels we detected significantly lower [3H]DAMGO binding to NMR compared to rat MOR, but no significant difference in DAMGO-induced cAMP inhibition. Strong DAMGO-induced MOR internalization was detectable using radioligand binding and confocal imaging in HEK293 cells expressing rat or NMR receptor, while morphine showed weak or no effects. In summary, we found minor functional differences between rat and NMR MOR suggesting that other differences e.g. in anatomical distribution of MOR underlie the NMR's extreme reaction to opioids.

  20. Hormones, reproduction and disease in the longest-lived rodent: the naked mole rat

    Directory of Open Access Journals (Sweden)

    Manlio Vinciguerra

    2011-05-01

    Full Text Available Aging is an inescapable human condition, made of hormonal, physical, and behavioral changes. Age-related illnesses and decline result from the interactions between genes and the environment. Life expectancy dramatically increased in the last century with the improvement in health cares and quality of life in the Western World. Despite these advances, the last 20 years of our life are often accompanied by an increased incidence of hormonalrelated diseases, such as cancer, metabolic, cardiovascular and neurological dysturbances. Aging research recently uncovered many of the molecular pathways involved in nutrients and hormonal regulation, and also involved in organism life span using simple laboratory animal model. However this knowledge did not translate in an ameliorated aging and cure for hormonal diseases in humans. A breakthrough in aging research came from recent studies on the longest-lived rodent [the naked mole rat (NMR]. NMR are able to reach ~30 years of age in good health. Because of their longevity and sustained health, NMR are a research model for successful aging. The most striking feature of NMR is perhaps their eusociality. Unique among mammals (eusociality is observed in insects such as bees and ants, NMR are organized in highly cooperative colonies. The aim of this review is to summarize our knowledge on hormonal and reproductive aspects in NMR. Furthermore, their resistance to pathological insults will be discussed.

  1. Protocol for the MoleMate™ UK Trial: a randomised controlled trial of the MoleMate system in the management of pigmented skin lesions in primary care [ISRCTN 79932379

    Directory of Open Access Journals (Sweden)

    Wilson Edward CF

    2010-05-01

    Full Text Available Abstract Background Suspicious pigmented lesions are a common presenting problem in general practice consultations; while the majority are benign a small minority are melanomas. Differentiating melanomas from other pigmented lesions in primary care is challenging: currently, 95% of all lesions referred to a UK specialist are benign. The MoleMate system is a new diagnostic aid, incorporating a hand-held SIAscopy scanner with a primary care diagnostic algorithm. This trial tests the hypothesis that adding the MoleMate system to current best primary care practice will increase the proportion of appropriate referrals of suspicious pigmented lesions to secondary care compared with current best practice alone. Methods/design The MoleMate UK Trial is a primary care based multi-centre randomised controlled trial, with randomisation at patient level using a validated block randomisation method for two age groups (45 years and under; 46 years and over. We aim to recruit adult patients seen in general practice with a pigmented skin lesion that cannot immediately be diagnosed as benign and the patient reassured. The trial has a 'two parallel groups' design, comparing 'best practice' with 'best practice' plus the MoleMate system in the intervention group. The primary outcome is the positive predictive value (PPV of referral defined as the proportion of referred lesions seen by secondary care experts that are considered 'clinically significant' (i.e. biopsied or monitored. Secondary outcomes include: the sensitivity, specificity and negative predictive value (NPV of the decision not to refer; clinical outcomes (melanoma thickness, 5 year melanoma incidence and mortality; clinician outcomes (Index of Suspicion, confidence, learning effects; patient outcomes (satisfaction, general and cancer-specific worry, and cost-utility. Discussion The MoleMate UK Trial tests a new technology designed to improve the management of suspicious pigmented lesions in primary care

  2. Reduced taste sensitivity in congenital blindness

    DEFF Research Database (Denmark)

    Gagnon, Lea; Kupers, Ron; Ptito, Maurice

    2013-01-01

    thresholds of the 5 basic tastants in 13 congenitally blind and 13 sighted control subjects. Participants also answered several eating habits questionnaires, including the Food Neophobia Scale, the Food Variety Seeking Tendency Scale, the Intuitive Eating Scale, and the Body Awareness Questionnaire. Our...... behavioral results showed that compared with the normal sighted, blind subjects have increased thresholds for taste detection and taste identification. This finding is at odds with the superior performance of congenitally blind subjects in several tactile, auditory and olfactory tasks. Our psychometric data...... further indicate that blind subjects more strongly rely on internal hunger and satiety cues, instead of external contextual or emotional cues, to decide when and what to eat. We suggest that the lower taste sensitivity observed in congenitally blind individuals is due to various blindness...

  3. Provably secure robust threshold partial blind signature

    Institute of Scientific and Technical Information of China (English)

    CAO Zhenfu; ZHU Haojin; LU Rongxing

    2006-01-01

    Threshold digital signature and blind signature are playing important roles in cryptography as well as in practical applications such as e-cash and e-voting systems.Over the past few years, many cryptographic researchers have made considerable headway in this field. However, to our knowledge, most of existing threshold blind signature schemes are based on the discrete logarithm problem. In this paper, we propose a new robust threshold partial blind signature scheme based on improved RSA cryptosystem.This scheme is the first threshold partial blind signature scheme based on factoring, and the robustness of threshold partial blind signature is also introduced. Moreover, in practical application, the proposed scheme will be especially suitable for blind signature-based voting systems with multiple administrators and secure electronic cash systems to prevent their abuse.

  4. Can acupuncture treatment be double-blinded?

    DEFF Research Database (Denmark)

    Vase, Lene; Baram, Sara; Takakura, Nobuari;

    2015-01-01

    acupuncturists were asked about perceived treatment allocation at the end of the study. To test if there were clues which led to identification of the treatment, deep dull pain associated with needle application and rotation (termed "de qi" in East Asian medicine), and patients' pain levels were assessed......Blinding protects against bias but the success of blinding is seldom assessed and reported in clinical trials including studies of acupuncture where blinding represents a major challenge. Recently, needles with the potential for double-blinding were developed, so we tested if acupuncture can be...... double-blinded in a randomized study of sixty-seven patients with acute pain ≥ 3 (0-10 scale following third molar removal) who received active acupuncture with a penetrating needle or placebo acupuncture with a non-penetrating needle. To test if acupuncture was administered double-blind, patients and...

  5. A new quantum blind signature with unlinkability

    Science.gov (United States)

    Shi, Wei-Min; Zhang, Jian-Biao; Zhou, Yi-Hua; Yang, Yu-Guang

    2015-08-01

    Recently, some quantum blind signature protocols have been proposed. However, the previous schemes cannot satisfy the unlinkability requirement. To overcome the drawback of unlinkability in the previous schemes, we propose a new quantum blind signature based on Bell states with the help of an authentic party. In this paper, we provide a method to inject a randomizing factor into a message when it is signed by the signer and then get rid of the blind factor from the blinded signature when it is verified by the verifier. Even when the message owner publishes the message-signature pair, the signer cannot identify the association between the message-signature pair and the blind signature he generated. Therefore, our scheme really realizes unlinkability property. At last, analysis results show that this scheme satisfies the basis security requirements of a weak signature such as no-counterfeiting, no-disavowing, blindness and traceability, and our total efficiency is not less than the previous schemes.

  6. Sensory augmentation for the blind

    Directory of Open Access Journals (Sweden)

    Silke Manuela Kärcher

    2012-03-01

    Full Text Available Enacted theories of consciousness conjecture that perception and cognition arise from an active experience of the regular relations that are tying together the sensory stimulation of different modalities and associated motor actions. Previous experiments investigated this concept by employing the technique of sensory substitution. Building on these studies, here we test a set of hypotheses derived from this framework and investigate the utility of sensory augmentation in handicapped people. We provide a late blind subject with a new set of sensorimotor laws: A vibro-tactile belt continually signals the direction of magnetic north. The subject completed a set of behavioral tests before and after an extended training period. The tests were complemented by questionnaires and interviews. This newly supplied information improved performance on different time scales. In a pointing task we demonstrate an instant improvement of performance based on the signal provided by the device. Furthermore, the signal was helpful in relevant daily tasks, often complicated for the blind, such as keeping a direction over longer distances or taking shortcuts in familiar environments. A homing task with an additional attentional load demonstrated a significant improvement after training. The subject found the directional information highly expedient for the adjustment of his inner maps of familiar environments and describes an increase in his feeling of security when exploring unfamiliar environments with the belt. The results give evidence for a firm integration of the newly supplied signals into the behavior of this late blind subject with better navigational performance and more courageous behavior in unfamiliar environments. Most importantly, the complementary information provided by the belt lead to a positive emotional impact with enhanced feeling of security. This experimental approach demonstrates the potential of sensory augmentation devices for the help of

  7. Biochemical Analyses and Nutritional Content of Four Castes of Subterranean Termites, Macrotermes subhyalinus (Rambur) (Isoptera: Termitidae): Differences in Digestibility and Anti-nutrient Contents among Castes

    OpenAIRE

    O. E. Ajayi

    2012-01-01

    Termite is used in many parts of the world but little is known about their biochemical properties and nutritional value as food. Protein digestibility and anti-nutrients of four castes (queen, worker, soldier and winged (alate)) of subterranean termite, Macrotermes subhyalinus were determined to evaluate the protein bioavailability and confirm nutritional value as food for human and animal consumption. Physico-chemical properties of the oil of each caste were also determined to reveal the pot...

  8. Endecous apterus: a new species of cave cricket from northeast Brazil, with comments on the use of subterranean habitats by Luzarinae crickets (Orthoptera: Grylloidea: Phalangopsidae: Luzarinae).

    Science.gov (United States)

    Souza-Dias, Pedro G B; Bolfarini, Márcio P; Nihei, Silvio S; De Mello, Francisco A G

    2014-01-01

    In this study we describe the first apterous species of Endecous Saussure (1878), collected in two caves at Ituaçu, Bahia State, Brazil. In Brazil, Endecous is the most widespread cricket in hypogean environments and its species can colonize caves and inhabit the entrance and the aphotic zones; Endecous species can also be found in the litter, rock gullies, crevices, burrows, and any natural cavities. The use of subterranean habitat by Endecous crickets and its related genera are discussed. PMID:24872041

  9. Blindness. [prosthetic devices and sensory aids

    Science.gov (United States)

    Pudenz, R. H.

    1974-01-01

    The possibilities are considered that modern electronics and engineering have to offer the individual with a damaged or disordered nervous system, especially the blind person. Discussed are the incidence and principal causes of blindness, past research activities, and a capsule review of some of the more interesting programs designed to provide the blind with the ability to be mobile in their environment and to read printed matter.

  10. Blind topological measurement-based quantum computation

    OpenAIRE

    Morimae, Tomoyuki; Fujii, Keisuke

    2011-01-01

    Blind quantum computation is a novel secure quantum-computing protocol that enables Alice, who does not have sufficient quantum technology at her disposal, to delegate her quantum computation to Bob, who has a fully fledged quantum computer, in such a way that Bob cannot learn anything about Alice's input, output and algorithm. A recent proof-of-principle experiment demonstrating blind quantum computation in an optical system has raised new challenges regarding the scalability of blind quantu...

  11. CERTIFICATELESS SIGNATURE AND BLIND SIGNATURE

    Institute of Scientific and Technical Information of China (English)

    Zhang Lei; Zhang Futai

    2008-01-01

    Certificateless public key cryptography is a new paradigm introduced by AI-Riyami and Paterson. It eliminates the need of the certificates in traditional public key cryptosystems and the key escrow problem in IDentity-based Public Key Cryptography (ID-PKC). Due to the advantages of the certificateless public key cryptography,a new efficient certificateless pairing-based signature scheme is presented,which has some advantages over previous constructions in computational cost. Based on this new signature scheme,a certificateless blind signature scheme is proposed. The security of our schemes is proven based on the hardness of computational Diffie-Hellman problem.

  12. Mola hidatiforme e doença trofoblástica gestacional Hydatidiform mole and gestational trophoblastic disease

    Directory of Open Access Journals (Sweden)

    Jurandyr Moreira de Andrade

    2009-02-01

    Full Text Available A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida. Sob a denominação de mola hidatiforme há duas entidades histopatológicas e clínicas: a mola parcial e a completa. As diferenças entre estas duas formas são importantes, devido ao risco de evolução para formas persistentes, ou seja, mais alto para as completas. O diagnóstico da mola hidatiforme, seu tratamento e seguimento após o tratamento inicial sofreram alterações importantes nos últimos anos. O número de pacientes assintomáticas tem aumentado devido ao emprego de ultrassonografia no início da gravidez. Para a resolução da mola hidatiforme é necessário evitar o emprego de medicamentos que induzam contrações uterinas e usar a vácuo-aspiração. Deve ser prescrito o método contraceptivo hormonal logo após o esvaziamento da mola. O seguimento é baseado nas dosagens seriadas semanais de gonadotrofinas coriônicas. É importante que o método empregado detecte todas as formas das gonadotrofinas coriônicas (molécula intacta, hiperglicosilada, subunidade β livre e fragmento central da subunidade β.The hydatiform mole is a relatively rare pregnancy complication, but with potential to evolve to forms which need systemic treatment and can be a threat to life. There are two histopathological and clinical entities under the name of hydatiform mole: the partial and the complete mole. The differences between the two forms are important due to risk of evolution to persistent forms, which is higher for the complete moles. The diagnosis, treatment and follow-up of hydatiform mole have been under important changes in the last years. The number of asymptomatic patients has increased, due to the use of ultrasonography at the onset of pregnancy. The use of medication that induces uterine contractions must be avoided, and vacuum

  13. Blindness and Insight in King Lear

    Institute of Scientific and Technical Information of China (English)

    岳元玉

    2008-01-01

    This paper intends to explore how William Shakespeare illustrates the theme of blindness and insight in his great tragedy "King Lear".Four characters’ deeds and their fate are used as a case study to examine what blindness is,what insight is,and the relationship between the two.The writer finds that by depicting the characters’ deeds and their fate in a double plot,Shakespeare renders the folly of blindness,the transition from blindness to insight,and the use of reason and thought to understand the truth.

  14. Application of Behavior Modification to Blind Children.

    Science.gov (United States)

    Hayes, Charles S.; Weinhouse, Ellen

    1978-01-01

    Research and application of principles of behavior modification with visually impaired and blind children are reviewed with particular attention to lower functioning multiply impaired children. (Author)

  15. 42 CFR 436.531 - Determination of blindness.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Determination of blindness. 436.531 Section 436.531... Requirements for Medicaid Eligibility Blindness § 436.531 Determination of blindness. In determining blindness... determine on behalf of the agency— (1) Whether the individual meets the definition of blindness; and...

  16. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

    Science.gov (United States)

    Brohus, Malene; Gorbunova, Vera; Faulkes, Chris G; Overgaard, Michael T; Conover, Cheryl A

    2015-01-01

    Naked mole-rats (Heterocephalus glaber) (NMRs) are the longest living rodents known. They show negligible senescence, and are resistant to cancers and certain damaging effects associated with aging. The insulin-like growth factors (IGFs) have pluripotent actions, influencing growth processes in virtually every system of the body. They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. The IGFs are likewise involved in progression of cancers by mediating survival signals in malignant cells. This report presents a full characterization of the IGF system in the NMR: ligands, receptors, IGF binding proteins (IGFBPs), and IGFBP proteases. A particular emphasis was placed on the IGFBP protease, pregnancy-associated plasma protein-A (PAPP-A), shown to be an important lifespan modulator in mice. Comparisons of IGF-related genes in the NMR with human and murine sequences indicated no major differences in essential parts of the IGF system, including PAPP-A. The protease was shown to possess an intact active site despite the report of a contradictory genome sequence. Furthermore, PAPP-A was expressed and translated in NMRs cells and retained IGF-dependent proteolytic activity towards IGFBP-4 and IGF-independent activity towards IGFBP-5. However, experimental data suggest differential regulatory mechanisms for PAPP-A expression in NMRs than those described in humans and mice. This overall description of the IGF system in the NMR represents an initial step towards elucidating the complex molecular mechanisms underlying longevity, and how these animals have evolved to ensure a delayed and healthy aging process. PMID:26694858

  17. The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat.

    Directory of Open Access Journals (Sweden)

    Malene Brohus

    Full Text Available Naked mole-rats (Heterocephalus glaber (NMRs are the longest living rodents known. They show negligible senescence, and are resistant to cancers and certain damaging effects associated with aging. The insulin-like growth factors (IGFs have pluripotent actions, influencing growth processes in virtually every system of the body. They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. The IGFs are likewise involved in progression of cancers by mediating survival signals in malignant cells. This report presents a full characterization of the IGF system in the NMR: ligands, receptors, IGF binding proteins (IGFBPs, and IGFBP proteases. A particular emphasis was placed on the IGFBP protease, pregnancy-associated plasma protein-A (PAPP-A, shown to be an important lifespan modulator in mice. Comparisons of IGF-related genes in the NMR with human and murine sequences indicated no major differences in essential parts of the IGF system, including PAPP-A. The protease was shown to possess an intact active site despite the report of a contradictory genome sequence. Furthermore, PAPP-A was expressed and translated in NMRs cells and retained IGF-dependent proteolytic activity towards IGFBP-4 and IGF-independent activity towards IGFBP-5. However, experimental data suggest differential regulatory mechanisms for PAPP-A expression in NMRs than those described in humans and mice. This overall description of the IGF system in the NMR represents an initial step towards elucidating the complex molecular mechanisms underlying longevity, and how these animals have evolved to ensure a delayed and healthy aging process.

  18. Comparison of the regional CO2 mole fraction filtering approaches at a WMO/GAW regional station in China

    Science.gov (United States)

    Fang, S. X.; Tans, P. P.; Steinbacher, M.; Zhou, L. X.; Luan, T.

    2015-12-01

    The identification of atmospheric CO2 observation data which are minimally influenced by very local emissions/removals is essential for trend analysis, for the estimation of regional sources and sinks, and for the modeling of long-range transport of CO2. In this study, four approaches are used to filter the atmospheric CO2 observation records from 2009 to 2011 at one World Meteorological Organization/Global Atmosphere Watch (WMO/GAW) regional station (Lin'an, LAN) in China. The methods are based on the concentration of atmospheric black carbon (BC), on a statistical approach (robust extraction of baseline signal, REBS), on CH4 as an auxiliary tracer (AUX), and on meteorological parameters (MET). All approaches do suitably well to capture the seasonal CO2 cycle at LAN. Differences are observed in the average regional mole fractions with annual values in the REBS method at least 1.7 ± 0.2 ppm higher than the other methods. The BC method may underestimate the regional CO2 mole fractions during the winter-spring period and should be treated with caution. The REBS method is a purely statistical method and it may also introduce errors on the regional CO2 mole fraction evaluations, as the filtered trend may be influenced by the "noisy" raw data series. Although there are correlations between CH4 and CO2 mole fractions at LAN, the different source/sink regimes may introduce bias on the regional CO2 estimation in the AUX method, typically in summer. Overall, the MET method seems to be the most favorable because it mainly focuses on the influence of potential local sources and sinks, and considers diurnal variations and meteorological conditions. Using the MET method, the annual growth rate of regional CO2 at LAN is determined to be 3.1 ± 0.01 ppm yr-1 (standard error) from 2009 to 2011.

  19. High specific activity N-Acetyl-3H-α-Aspartyl- L-Glutamic at micro mole scale

    International Nuclear Information System (INIS)

    High specific activity N-Acetyl-3H- α -Aspartyl-I-Glutamic acid at micro mole scale in prepared acetylating L- α -Aspartyl-L-glutamic with 3H-acetic anhydride in re distilled toluene. The product le purified through cationic and anionic columns. The radiochemical purity as determined by thin-layer chromatography is greater then 99% at the time preparation. (Author) 5 refs

  20. Study of the regional CO2 mole fractions filtering approach at a WMO/GAW regional station in China

    Directory of Open Access Journals (Sweden)

    S. X. Fang

    2015-07-01

    Full Text Available The identification of atmospheric CO2 observation data which is minimally influenced by very local emissions/removals is essential for the estimation of trend analysis, regional sources and sinks, and for modeling of long-range transport of CO2. In this study, four approaches are used to filter the atmospheric CO2 observation records from 2009 to 2011 at one World Meteorological Organization/Global Atmosphere Watch (WMO/GAW regional station (Lin'an, LAN in China. The methods are based on the atmospheric black carbon concentration (BC, on a statistical approach (REBS, on CH4 as auxiliary tracer (AUX and on meteorological parameters (MET. All approaches do suitably well to capture the seasonal CO2 cycle at LAN. Differences are observed in the average regional mole fractions with annual values in the REBS method at least 1.7 ± 0.2 ppm higher than the other methods. The BC method may underestimate the regional CO2 mole fractions during winter-spring period and should be treated with caution. The REBS method is a purely statistical method and it may also introduce errors on the regional CO2 mole fractions evaluations, as the filtered trend may be deviated by the "noisy" raw data series. Although there are correlations between CH4 and CO2 mole fractions at LAN, the different source/sink regimes may introduce bias on the regional CO2 estimation in the AUX method, typically in summer. Overall, the MET method seems to be the most favorable because it mainly focuses on the influence of potential local sources and sinks and considers diurnal variations, local topography, and meteorological conditions. Using the MET method, the annual growth rate of regional CO2 at LAN is determined to be 3.1 ± 0.01 ppm yr−1 (standard error from 2009 to 2013.

  1. Pigmentary Markers in Danes – Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome

    OpenAIRE

    Johansen, Peter; Andersen, Jeppe Dyrberg; Madsen, Linnea Nørgård; Ullum, Henrik; Glud, Martin; Børsting, Claus; Gniadecki, Robert; Morling, Niels

    2016-01-01

    To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis) contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total nevus count, and the familial atypical multiple mole and melanoma (FAMMM) syndrome. We typed 32 pigmentary SNP markers and sequenced MC1R in 246 healthy individuals and 116 individuals attending periodic control for malignant melanoma develop...

  2. Challenging the inbreeding hypothesis in a eusocial mammal: population genetics of the naked mole-rat, Heterocephalus glaber.

    Science.gov (United States)

    Ingram, Colleen M; Troendle, Nicholas J; Gill, Clare A; Braude, Stanton; Honeycutt, Rodney L

    2015-10-01

    The role of genetic relatedness in the evolution of eusociality has been the topic of much debate, especially when contrasting eusocial insects with vertebrates displaying reproductive altruism. The naked mole-rat, Heterocephalus glaber, was the first described eusocial mammal. Although this discovery was based on an ecological constraints model of eusocial evolution, early genetic studies reported high levels of relatedness in naked mole-rats, providing a compelling argument that low dispersal rates and consanguineous mating (inbreeding as a mating system) are the driving forces for the evolution of this eusocial species. One caveat to accepting this long-held view is that the original genetic studies were based on limited sampling from the species' geographic distribution. A growing body of evidence supports a contrary view, with the original samples not representative of the species-rather reflecting a single founder event, establishing a small population south of the Athi River. Our study is the first to address these competing hypotheses by examining patterns of molecular variation in colonies sampled from north and south of the Athi and Tana rivers, which based on our results, serve to isolate genetically distinct populations of naked mole-rats. Although colonies south of the Athi River share a single mtDNA haplotype and are fixed at most microsatellite loci, populations north of the Athi River are considerably more variable. Our findings support the position that the low variation observed in naked mole-rat populations south of the Athi River reflects a founder event, rather than a consequence of this species' unusual mating system. PMID:26407630

  3. CFD modelling of most probable bubble nucleation rate from binary mixture with estimation of components' mole fraction in critical cluster

    Science.gov (United States)

    Hong, Ban Zhen; Keong, Lau Kok; Shariff, Azmi Mohd

    2016-05-01

    The employment of different mathematical models to address specifically for the bubble nucleation rates of water vapour and dissolved air molecules is essential as the physics for them to form bubble nuclei is different. The available methods to calculate bubble nucleation rate in binary mixture such as density functional theory are complicated to be coupled along with computational fluid dynamics (CFD) approach. In addition, effect of dissolved gas concentration was neglected in most study for the prediction of bubble nucleation rates. The most probable bubble nucleation rate for the water vapour and dissolved air mixture in a 2D quasi-stable flow across a cavitating nozzle in current work was estimated via the statistical mean of all possible bubble nucleation rates of the mixture (different mole fractions of water vapour and dissolved air) and the corresponding number of molecules in critical cluster. Theoretically, the bubble nucleation rate is greatly dependent on components' mole fraction in a critical cluster. Hence, the dissolved gas concentration effect was included in current work. Besides, the possible bubble nucleation rates were predicted based on the calculated number of molecules required to form a critical cluster. The estimation of components' mole fraction in critical cluster for water vapour and dissolved air mixture was obtained by coupling the enhanced classical nucleation theory and CFD approach. In addition, the distribution of bubble nuclei of water vapour and dissolved air mixture could be predicted via the utilisation of population balance model.

  4. Isolation and partial characterization of a highly divergent lineage of hantavirus from the European mole (Talpa europaea).

    Science.gov (United States)

    Gu, Se Hun; Kumar, Mukesh; Sikorska, Beata; Hejduk, Janusz; Markowski, Janusz; Markowski, Marcin; Liberski, Paweł P; Yanagihara, Richard

    2016-01-01

    Genetically distinct hantaviruses have been identified in five species of fossorial moles (order Eulipotyphla, family Talpidae) from Eurasia and North America. Here, we report the isolation and partial characterization of a highly divergent hantavirus, named Nova virus (NVAV), from lung tissue of a European mole (Talpa europaea), captured in central Poland in August 2013. Typical hantavirus-like particles, measuring 80-120 nm in diameter, were found in NVAV-infected Vero E6 cells by transmission electron microscopy. Whole-genome sequences of the isolate, designated NVAV strain Te34, were identical to that amplified from the original lung tissue, and phylogenetic analysis of the full-length L, M and S segments, using maximum-likelihood and Bayesian methods, showed that NVAV was most closely related to hantaviruses harbored by insectivorous bats, consistent with an ancient evolutionary origin. Infant Swiss Webster mice, inoculated with NVAV by the intraperitoneal route, developed weight loss and hyperactivity, beginning at 16 days, followed by hind-limb paralysis and death. High NVAV RNA copies were detected in lung, liver, kidney, spleen and brain by quantitative real-time RT-PCR. Neuropathological examination showed astrocytic and microglial activation and neuronal loss. The first mole-borne hantavirus isolate will facilitate long-overdue studies on its infectivity and pathogenic potential in humans. PMID:26892544

  5. A bilogarithmic method for the spectrophotometric evaluation of stability constants of 1:1 weak complexes from mole ratio data.

    Science.gov (United States)

    Boccio, Maravillas; Sayago, Ana; Asuero, Agustín G

    2006-08-01

    The absorbance changes that occur when the mole ratio of the components of ligand complex equilibria is varied while the concentration of one component is kept constant (mole ratio method) allow evaluating stability constants in favourable conditions. Values of the corresponding stability (association) constants are normally assigned on the basis of spectrophotometric analysis. Determination of stability constants can be performed by a number of linear procedures, but most of these, suffer from theoretical and practical drawbacks, e.g., linear transformation of the rectangular hyperbola type of binding constants, is valid only when one of the two species is present in a large excess. A rigorous treatment of the experimental mole ratio data for 1:1 weak complexes is carried out in this paper with the aim of eliminating some of the assumptions involved in the other methods usually applied for evaluating stability constants. Orthogonal regression is required in order to take into account the error in both axes. The method has been applied to literature data for the iron(III)-thiocyanate and nickel(II)-selenocyanate systems, as well as to a number of host-guest cyclodextrin complexes. PMID:16647826

  6. Individual Differences in Susceptibility to Inattentional Blindness

    Science.gov (United States)

    Seegmiller, Janelle K.; Watson, Jason M.; Strayer, David L.

    2011-01-01

    Inattentional blindness refers to the finding that people do not always see what appears in their gaze. Though inattentional blindness affects large percentages of people, it is unclear if there are individual differences in susceptibility. The present study addressed whether individual differences in attentional control, as reflected by…

  7. Mentoring Transition-Age Youth with Blindness

    Science.gov (United States)

    Bell, Edward C.

    2012-01-01

    This article reports on a mentoring project designed for transition-age youth (ages 16-26) who are persons with legal blindness. Youth were matched with adult mentors who were also persons with blindness but who have achieved academic and career success. Results demonstrate that youth who participated in the project for 2 years had significant…

  8. Blind Equalization Based on Evolution Strategies

    Institute of Scientific and Technical Information of China (English)

    SongYu; ZhangXianda; 等

    1997-01-01

    Conventional blind equalization algorithms suffer from ill convergence to local minima and slow convergence speed.This paper proposes a novel blind equalization algorithm.using random search methods-evolution strategies and existing cost functions,Simulation results verify the fast and global convergence of the proposed algorithm.

  9. Blavigator: a navigation aid for blind persons

    OpenAIRE

    José, João; MORENO, M; Pinilla-Dutoit, J.; Rodrigues, J. M. F.; du Buf, J. M. H.

    2012-01-01

    Blavigator (blind navigator) is a vision aid for blind and visuaIIy impaired persons. It supports local navigation by detecting waIkable paths in the immediate vicinity of the user. It guides the user for centering on the path.

  10. Economic burden of blindness in India

    Directory of Open Access Journals (Sweden)

    Shamanna B

    1998-01-01

    Full Text Available Economic analysis is one way to determine the allocation of scarce resources for health-care programs. The initial step in this process is to estimate in economic terms the burden of diseases and the benefit from interventions for prevention and treatment of these diseases. In this paper, the direct and indirect economic loss due to blindness in India is calculated on the basis of certain assumptions. The cost of treating cataract blindness in India is estimated at current prices. The economic burden of blindness in India for the year 1997 based on our assumptions is Rs. 159 billion (US$ 4.4 billion, and the cumulative loss over lifetime of the blind is Rs. 2,787 billion (US$ 77.4 billion. Childhood blindness accounts for 28.7% of this lifetime loss. The cost of treating all cases of cataract blindness in India is Rs. 5.3 billion (US$ 0.15 billion. Similar estimates for causes of blindness other than cataract have to be made in order to develop a comprehensive approach to deal with blindness in India.

  11. Genetics Home Reference: autosomal dominant congenital stationary night blindness

    Science.gov (United States)

    ... stationary night blindness autosomal dominant congenital stationary night blindness Enable Javascript to view the expand/collapse boxes. ... Close All Description Autosomal dominant congenital stationary night blindness is a disorder of the retina , which is ...

  12. Genetics Home Reference: X-linked congenital stationary night blindness

    Science.gov (United States)

    ... stationary night blindness X-linked congenital stationary night blindness Enable Javascript to view the expand/collapse boxes. ... Close All Description X-linked congenital stationary night blindness is a disorder of the retina , which is ...

  13. Tactile maze solving in congenitally blind individuals

    DEFF Research Database (Denmark)

    Gagnon, Léa; Kupers, Ron; Schneider, Fabien C;

    2010-01-01

    Vision is undoubtedly important for navigation although not essential as blind individuals outperform their blindfolded seeing counterparts in a variety of navigational tasks. It is believed that the blind's superior performance is because of their efficient use of proprioceptive signals and...... environmental cues such as temperature and echolocation. We hypothesize that by limiting these cues, blind individuals will lose their advantage compared with controls in spatial navigation tasks. We therefore evaluated the performance of blind and sighted individuals in small-scale, tactile multiple T mazes....... Our results show that blindfolded sighted controls outperformed blind participants in the route-learning tasks. This suggests that, contrary to indoor large-scale spaces, navigational skills inside small-scale spaces benefit from visual experience....

  14. An ECC-Based Blind Signature Scheme

    Directory of Open Access Journals (Sweden)

    Fuh-Gwo Jeng

    2010-08-01

    Full Text Available Cryptography is increasingly applied to the E-commerce world, especially to the untraceable payment system and the electronic voting system. Protocols for these systems strongly require the anonymous digital signature property, and thus a blind signature strategy is the answer to it. Chaum stated that every blind signature protocol should hold two fundamental properties, blindness and intractableness. All blind signature schemes proposed previously almost are based on the integer factorization problems, discrete logarithm problems, or the quadratic residues, which are shown by Lee et al. that none of the schemes is able to meet the two fundamental properties above. Therefore, an ECC-based blind signature scheme that possesses both the above properties is proposed in this paper.

  15. Blindness in designing intelligent systems

    Science.gov (United States)

    Denning, Peter J.

    1988-01-01

    New investigations of the foundations of artificial intelligence are challenging the hypothesis that problem solving is the cornerstone of intelligence. New distinctions among three domains of concern for humans--description, action, and commitment--have revealed that the design process for programmable machines, such as expert systems, is based on descriptions of actions and induces blindness to nonanalytic action and commitment. Design processes focusing in the domain of description are likely to yield programs like burearcracies: rigid, obtuse, impersonal, and unable to adapt to changing circumstances. Systems that learn from their past actions, and systems that organize information for interpretation by human experts, are more likely to be successful in areas where expert systems have failed.

  16. Blind-date Conversation Joining

    Directory of Open Access Journals (Sweden)

    Luca Cesari

    2013-07-01

    Full Text Available We focus on a form of joining conversations among multiple parties in service-oriented applications where a client may asynchronously join an existing conversation without need to know in advance any information about it. More specifically, we show how the correlation mechanism provided by orchestration languages enables a form of conversation joining that is completely transparent to clients and that we call 'blind-date joining'. We provide an implementation of this strategy by using the standard orchestration language WS-BPEL. We then present its formal semantics by resorting to COWS, a process calculus specifically designed for modelling service-oriented applications. We illustrate our approach by means of a simple, but realistic, case study from the online games domain.

  17. The PHENIX Hadron Blind Detector

    International Nuclear Information System (INIS)

    Dielectron measurements by the PHENIX Experiment at RHIC are limited by the combinatorial background from electrons and positrons which are not produced in the same pair. The Hadron Blind Detector will allow a substantial reduction of this background by correctly identifying dielectrons from photon conversions and pion Dalitz decays which dominate the signal in the low mass region of the spectrum. Triple GEM stacks, with a CsI photocathode deposited on the uppermost GEM, detect Cherenkov light produced by electrons in a CF4 radiator. The transparency of CF4, high quantum efficiency of CsI in the UV, and absence of a window between the gas radiator and the GEMs allow a large photoelectron yield, while minimizing the hadron signal. Results from the HBD in RHIC's Run-7 and preparations for upcoming runs are discussed.

  18. Evaluation of polyphenols-rich natural compounds as treatments to prevent attacks by subterranean and drywood termites: preliminary results

    Directory of Open Access Journals (Sweden)

    Lara Maistrello

    2011-08-01

    Full Text Available In the view to find sustainable methods to prevent termite attacks to wooden objects and structural timbers, this study represents a preliminary step in the evaluation of some natural substances considered as effective by some African popular traditions. Dark shea cake, obtained from the kernels of Vitellaria paradoxa (Sapotaceae, is the phase just before the extraction of shea (= karitè butter. In some West African regions, by-products from this extraction are traditionally believed to protect houses from termites. To verify if this practice has scientific basis, shea cake was used in experiments with both subterranean and drywood termites, respectively Reticulitermes lucifugus (Rossi (Rhinotermitidae and Kalotermes flavicollis (Fabricius (Kalotermitidae. As shea nuts are extremely rich in polyphenols, the trials included a comparison with tannins from chestnut (Castanea sativa. Short-term experiments to evaluate repellency and feeding deterrence of the two compounds were performed. Results showed differences in the behavior of the two termites species and that shea cake is significantly more repellent than chestnut tannins, especially for K. flavicollis. No feeding deterrence activity was detected for either substance for either termite species. Further investigation is currently being performed to better clarify how these compounds affect termite biology.

  19. Arbuscular mycorrhizal fungi can decrease the uptake of uranium by subterranean clover grown at high levels of uranium in soil

    International Nuclear Information System (INIS)

    Subterranean clover inoculated or not with the arbuscular mycorrhizal (AM) fungus Glomus intraradices was grown on soil containing six levels of 238U in the range 0-87 mg kg-1. Increasing U concentration in soil enhanced the U concentration in roots and shoots of both mycorrhizal and nonmycorrhizal plants but had no significant effects on plant dry matter production or root AM colonization. Mycorrhizas increased the shoot dry matter and P concentration in roots and shoots, while in most cases, it decreased the Ca, Mg and K concentrations in plants. The AM fungus influenced U concentration in plants only in the treatment receiving 87 mg U kg-1 soil. In this case, U concentration in shoots of nonmycorrhizal plants was 1.7 times that of shoots of mycorrhizal plants. These results suggested that mycorrhizal fungi can limit U accumulation by plants exposed to high levels of U in soil. - Plant mycorrhization may decrease U concentration in shoots of plants grown at high level of U in soil

  20. Arbuscular mycorrhizal fungi can decrease the uptake of uranium by subterranean clover grown at high levels of uranium in soil

    Energy Technology Data Exchange (ETDEWEB)

    Rufyikiri, Gervais; Huysmans, Lien; Wannijn, Jean; Hees, May van; Leyval, Corinne; Jakobsen, Iver

    2004-08-01

    Subterranean clover inoculated or not with the arbuscular mycorrhizal (AM) fungus Glomus intraradices was grown on soil containing six levels of {sup 238}U in the range 0-87 mg kg{sup -1}. Increasing U concentration in soil enhanced the U concentration in roots and shoots of both mycorrhizal and nonmycorrhizal plants but had no significant effects on plant dry matter production or root AM colonization. Mycorrhizas increased the shoot dry matter and P concentration in roots and shoots, while in most cases, it decreased the Ca, Mg and K concentrations in plants. The AM fungus influenced U concentration in plants only in the treatment receiving 87 mg U kg{sup -1} soil. In this case, U concentration in shoots of nonmycorrhizal plants was 1.7 times that of shoots of mycorrhizal plants. These results suggested that mycorrhizal fungi can limit U accumulation by plants exposed to high levels of U in soil. - Plant mycorrhization may decrease U concentration in shoots of plants grown at high level of U in soil.

  1. Invasive Complete Hydatidiform Moles: Analysis of a Case Series With Genotyping.

    Science.gov (United States)

    Bynum, Jennifer; Murphy, Kathleen M; DeScipio, Cheryl; Beierl, Katie; Adams, Emily; Anderson, Derek; Vang, Russell; Ronnett, Brigitte M

    2016-03-01

    Complete hydatidiform moles (CHM) are purely androgenetic conceptions, with most (∼85%) arising from fertilization of an egg lacking maternal DNA by a single sperm that duplicates (homozygous/monospermic 46,XX) and a small subset arising via fertilization by 2 sperms (heterozygous/dispermic 46,XY or 46,XX). It remains controversial if heterozygous/dispermic CHMs have a significantly greater risk of persistent gestational trophoblastic disease. Analysis of zygosity of CHMs with and without invasion at presentation, including invasive CHMs with concurrent atypical trophoblastic proliferations concerning for or consistent with choriocarcinoma, has not been specifically addressed. In a prospective series of 1024 products of conception specimens subjected to immunohistochemical analysis of p57 expression and molecular genotyping with short tandem-repeat markers, 288 CHMs were diagnosed, of which 126 were genotyped, including 16 invasive CHMs. Zygosity was compared between those with and without invasion. Of the 16 study cases, 12 (75%) were homozygous/monospermic XX and 4 (25%) were heterozygous/dispermic (3 XY and 1 XX). Of the 110 genotyped noninvasive CHMs, 96 (87%) were homozygous/monospermic XX and 14 (13%) were heterozygous/dispermic (12 XY, 2 XX). Comparison of the zygosity results for the invasive CHMs (study group) with the noninvasive CHMs in the database did not demonstrate a statistically significant difference (P=0.24, Fisher exact test). In addition, of the 3 cases associated with metastatic gestational trophoblastic disease (pulmonary nodules) at presentation, 2 were homozygous/monospermic XX, indicating that this form is not without risk of significant gestational trophoblastic disease. Thus, the current study has demonstrated a higher frequency of heterozygous/dispermic CHMs among invasive cases compared with those lacking invasion, but does not support the use of zygosity data for risk assessment of CHMs. A persistent, unresolved diagnostic challenge

  2. The effects of oxotremorine, epibatidine, atropine, mecamylamine and naloxone in the tail-flick, hot-plate, and formalin tests in the naked mole-rat (Heterocephalus glaber)

    DEFF Research Database (Denmark)

    Dulu, Thomas D; Kanui, Titus I; Towett, Philemon K;

    2014-01-01

    The naked mole-rat (Heterocephalus glaber) is a promising animal model for the study of pain mechanisms, therefore a thorough characterization of this species is essential. The aim of the present study was to establish the naked mole-rat as a model for studying the cholinergic receptor system in ...... antinociceptive effects of cholinergic agonists, it is suggested that the cholinergic antinociception acts via a gateway facilitated by opioid receptor blockage; however, the precise interaction between these receptor systems needs further investigation....

  3. IMPLEMENTATION OF BLIND DIGITAL SIGNATURE USING ECC

    Directory of Open Access Journals (Sweden)

    MS.DHANASHREE M.KUTHE

    2012-10-01

    Full Text Available In this paper, we proposed a scheme to implement ‘ElectronicVoting’ an important application of Blind digital Signature usingelliptic curve cryptographic algorithm. The selection of thisalgorithm is its difficulty in solving it. The algorithm is used incombination with the blinding factor to scramble the contents ofthe message to be signed by the signer so that the signer do notcome to know what the message is all about. The signer then signsthe blinded message that is the vote of the voter and authenticateshim/her.

  4. Blind and visually impared in urban traffic

    OpenAIRE

    Berus, Anja

    2012-01-01

    In this thesis I present accessories, techniques and systems which enable the blind and visually impaired to move in urban traffic. The blind and visually impaired participate in traffic as pedestrians, passengers in cars and in means of public transport etc. This thesis is therefore designed so that it covers all these fields. The survey at the end of the thesis presents the needs and thoughts of the blind and visually impaired as well as the views of those who can see on the involvement of ...

  5. Blind image deconvolution methods and convergence

    CERN Document Server

    Chaudhuri, Subhasis; Rameshan, Renu

    2014-01-01

    Blind deconvolution is a classical image processing problem which has been investigated by a large number of researchers over the last four decades. The purpose of this monograph is not to propose yet another method for blind image restoration. Rather the basic issue of deconvolvability has been explored from a theoretical view point. Some authors claim very good results while quite a few claim that blind restoration does not work. The authors clearly detail when such methods are expected to work and when they will not. In order to avoid the assumptions needed for convergence analysis in the

  6. Ten years left to eliminate blinding trachoma

    Directory of Open Access Journals (Sweden)

    Haddad D.

    2010-09-01

    Full Text Available n 1997, the World Health Organization formed the Global Alliance to Eliminate Blinding Trachoma by 2020 (GET 2020, a coalition of governmental, non-governmental, research, and pharmaceutical partners. In 1998, the World Health Assembly urged member states to map blinding trachoma in endemic areas, implement the SAFE strategy (which stands for surgery for trichiasis, antibiotics, facial-cleanliness and environmental change, such as clean water and latrines and collaborate with the global alliance in its work to eliminate blinding trachoma.

  7. Enhanced heat discrimination in congenital blindness

    DEFF Research Database (Denmark)

    Slimani, Hocine; Ptito, Maurice; Kupers, Ron

    2015-01-01

    domain. We therefore compared the capacity to detect small temperature increases in innocuous heat in a group of 12 congenitally blind and 12 age and sex-matched normally sighted participants. In addition, we also tested for group differences in the effects of spatial summation on temperature......There is substantial evidence that congenitally blind individuals perform better than normally sighted controls in a variety of auditory, tactile and olfactory discrimination tasks. However, little is known about the capacity of blind individuals to make fine discriminatory judgments in the thermal...... and are more susceptible to spatial summation of heat....

  8. Blind extraction of exoplanetary spectra

    Science.gov (United States)

    Morello, Giuseppe; Waldmann, Ingo P.; Tinetti, Giovanna

    2016-06-01

    In the last decade, remote sensing spectroscopy enabled characterization of the atmospheres of extrasolar planets. Transmission and emission spectra of tens of transiting exoplanets have been measured with multiple instruments aboard Spitzer and Hubble Space Telescopes as well as ground-based facilities, revealing the presence of atomic, ionic and molecular species in their atmospheres, and constraining their temperature and pressure profiles.Early analyses were somehow heuristic both in measuring the spectra and in their interpretation, leading to some controversies in the literature.A photometric precision of 0.01% is necessary to detect the atmospheric spectral modulations. Current observatories, except Kepler, were not designed to achieve this precision. Data reduction is necessary to minimize the effect of instrument systematics in order to achieve the target precision. In the past, parametric models have extensively been used by most teams to remove correlated noise with the aid of auxiliary information of the instrument, the so-called optical state vectors (OSVs). Such OSVs can include inter- and intra-pixel position of the star or its spectrum, instrument temperatures and inclinations, and/or other parameters. In some cases, different parameterizations led to discrepant results.We recommend the use of blind non-parametric data detrending techniques to overcome those issues. In particular, we adopt Independent Component Analysis (ICA), i.e. a blind source separation (BSS) technique to disentangle the multiple instrument systematics and astrophysical signals in transit/eclipse light curves. ICA does not require a model for the systematics, and for this reason, it can be applied to any instrument with little changes, if any. ICA-based algorithms have been applied to Spitzer/IRAC and synthetic observations in photometry (Morello et al. 2014, 2015, 2016; Morello 2015) and to Hubble/NICMOS and Spitzer/IRS in spectroscopy (Waldmann 2012, 2014, Waldmann et al. 2013

  9. Effect of the Ti/B4C mole ratio on the reaction products and reaction mechanism in an Al–Ti–B4C powder mixture

    International Nuclear Information System (INIS)

    The effect of the Ti/B4C mole ratio on the fabrication behavior of Al composites is investigated using Al–Ti–B4C powder mixtures as reactants. The quick spontaneous infiltration (QSI) process combined with the combustion reaction and DTA analysis were used. According to the thermodynamic predictions, which are verified in the experimental results, TiB2 is formed in all the samples whereas TiC is only formed in reactants with a Ti/B4C mole ratio of more than two. The C atoms from the reacted B4C do not move into TiC but instead they move into Al3BC or Al4C3 when the Ti/B4C mole ratio is less than two. In addition, the reaction mechanism with a Ti/B4C mole ratio of 0.75 is investigated extensively. - Highlights: • The critical role of the Ti/B4C mole ratio on the reaction products of Al–Ti–B4C was studied using experiments. • The experimental results are also supported by thermodynamic calculations presented in this paper. • The reaction mechanism with a Ti/B4C mole ratio of 0.75 is investigated extensively

  10. Impact of indium mole fraction on the quantum transport of ultra-scaled In x Ga1- x As double-gate Schottky MOSFET: tight-binding approach

    Science.gov (United States)

    Ahangari, Zahra

    2016-02-01

    This paper explores the impact of indium mole fraction on the electrical characteristic of In x Ga1- x As double-gate Schottky MOSFET (SBFET) in nanoscale regime. A 20-band sp 3 d 5 s * tight-binding formalism is applied to compute the bandstructure of ultra-thin body structure as a function of indium mole fraction. The injection velocity of carriers is increased as the indium mole fraction approaches to x = 1. Quantum confinement results in an increment of the effective Schottky barrier height especially for the increased values of indium mole fraction. The ultra-scaled In x Ga1- x As SBFET suffers from a low conduction band DOS in the Γ valley that results in serious degradation of the gate capacitance. The electrical characteristic of this device is considered by solving self-consistent 2D Schrődinger-Poisson equations based on non-equilibrium Green's function formalism. For channel thicknesses where the effect of quantum confinement on the gate capacitance is not dominant, shrinking the channel thickness besides increasing the indium mole fraction improves the electrical characteristic of the device. However, for the ultra-scaled structure, the indium mole fraction enhancement degrades the device performance due to the enhanced value of Schottky barrier height and low DOS.

  11. Investigations of subterranean microorganisms and their importance for performance assessment of radioactive waste disposal. Results and conclusions achieved during the period 1995 to 1997

    Energy Technology Data Exchange (ETDEWEB)

    Pedersen, K. [Goeteborg Univ. (Sweden). Dept. of General and Marine Microbiology

    1997-11-01

    In 1987, microbiology became a part of the Swedish scientific program for the safe disposal of high level nuclear waste (HLW). The goal of the microbiology sub-program is to understand how subterranean microorganisms will interact with the performance of a future HLW repository. The Swedish research program on subterranean microbiology has mainly been performed at two sites in granitic rock aquifers at depths ranging from 70 m down to 1240 m; the Stripa research mine in the middle of Sweden and the Aespoe hard rock laboratory (HRL) situated on the south eastern coast of Sweden. Some work has also been performed in co-operation with other national or international research groups in Sweden, Canada and at the natural analogue sites in Oklo in Gabon and Maqarin in Jordan. The most recent report in the SKB technical report series on microbiology and performance assessment, SKB-TR--95-10, gave the state of the art regarding microorganisms and their importance for performance assessment. That report is recommended as a source of knowledge about basic microbiology, microbial ecology of subterranean environments and the nuclear waste disposal concept in a microbiological perspective. The present report summarises results and conclusions achieved during the period 1995 to 1997 and is a continuation of SKB TR 95-10. The report is structured as summary which explains and analyses the obtained results and conclusions in a performance assessment perspective. The scientific basis for the summary is an enclosed series of eleven papers of which eight have gone through an international peer review process for publication in international scientific journals and reports and papers published earlier. 413 refs, 56 figs, 39 tabs.

  12. Investigations of subterranean microorganisms and their importance for performance assessment of radioactive waste disposal. Results and conclusions achieved during the period 1995 to 1997

    International Nuclear Information System (INIS)

    In 1987, microbiology became a part of the Swedish scientific program for the safe disposal of high level nuclear waste (HLW). The goal of the microbiology sub-program is to understand how subterranean microorganisms will interact with the performance of a future HLW repository. The Swedish research program on subterranean microbiology has mainly been performed at two sites in granitic rock aquifers at depths ranging from 70 m down to 1240 m; the Stripa research mine in the middle of Sweden and the Aespoe hard rock laboratory (HRL) situated on the south eastern coast of Sweden. Some work has also been performed in co-operation with other national or international research groups in Sweden, Canada and at the natural analogue sites in Oklo in Gabon and Maqarin in Jordan. The most recent report in the SKB technical report series on microbiology and performance assessment, SKB-TR--95-10, gave the state of the art regarding microorganisms and their importance for performance assessment. That report is recommended as a source of knowledge about basic microbiology, microbial ecology of subterranean environments and the nuclear waste disposal concept in a microbiological perspective. The present report summarises results and conclusions achieved during the period 1995 to 1997 and is a continuation of SKB TR 95-10. The report is structured as summary which explains and analyses the obtained results and conclusions in a performance assessment perspective. The scientific basis for the summary is an enclosed series of eleven papers of which eight have gone through an international peer review process for publication in international scientific journals and reports and papers published earlier

  13. Iterated Gate Teleportation and Blind Quantum Computation.

    Science.gov (United States)

    Pérez-Delgado, Carlos A; Fitzsimons, Joseph F

    2015-06-01

    Blind quantum computation allows a user to delegate a computation to an untrusted server while keeping the computation hidden. A number of recent works have sought to establish bounds on the communication requirements necessary to implement blind computation, and a bound based on the no-programming theorem of Nielsen and Chuang has emerged as a natural limiting factor. Here we show that this constraint only holds in limited scenarios, and show how to overcome it using a novel method of iterated gate teleportations. This technique enables drastic reductions in the communication required for distributed quantum protocols, extending beyond the blind computation setting. Applied to blind quantum computation, this technique offers significant efficiency improvements, and in some scenarios offers an exponential reduction in communication requirements. PMID:26196609

  14. Teaching Introductory Statistics to Blind Students

    Science.gov (United States)

    Marson, Stephen M.; Harrington, Charles F.; Walls, Adam

    2013-01-01

    The challenges of learning statistics, particularly distributions and their characteristics, can be potentially monumental for vision impaired and blind students. The authors provide some practical advice for teaching these students.

  15. Assertive Skills Training for the Blind.

    Science.gov (United States)

    Everhart, Gary; And Others

    1980-01-01

    The article describes how a rehabilitation center for the blind, aware that many clients were inept in dealing with society at large, instituted an assertive skills training program to improve client skills in this area. (Author/SBH)

  16. Accommodating blind and partially sighted clients

    OpenAIRE

    England, Gary; Gebbels, Tim; Whelan, Chantelle; Freeman, Sarah

    2014-01-01

    Veterinary surgeons provide an important service to blind and partially sighted guide dog owners. By adopting basic disability awareness and visual impairment training, practices can ensure that the assistance needs of those clients are met, facilitating access to veterinary care.

  17. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... Scientist Video Series Why can’t you see colors well in the dark? Do fish have eyelids? ... video series. Dr. Sheldon Miller answers questions about color blindness, whether it can be treated, and how ...

  18. Evaluation of Metarhizium anisopliae var. anisopliae (Deuteromycotina: Hyphomycete Isolates and their Effects on Subterranean Termite Coptotermes curvignathus (Isoptera: Rhinotermitidae

    Directory of Open Access Journals (Sweden)

    Pik-Kheng Hoe

    2009-01-01

    Full Text Available Problem statement: Coptotermes curvignathus (Isoptera: Rhinotermitidae is a common termite pest found in oil palm plantation planted on peat. Currently, the control methods focus on using insecticides that lead to high cost and adverse effect to the environment. Approach: Biological control like the use of entomopathogens provides an alternative control method for termite infestation problem. However, several factors need to be investigated in order to obtain a virulent strain with potential to be developed into a biopesticide. Results: Three local isolates (MG, LR2 and TA of Metarhizium anisopliae were obtained and identified as M. anisopliae var. anisopliae using molecular techniques. Growth performance of isolates on four basal media namely, Potato Dextrose Agar (PDA, Potato Dextrose Agar with 1% yeast extract (PDAY, Sabaroud Dextrose Agar (SDA and Sabaroud Dextrose Agar with 1% yeast extract (SDAY was assessed. The pathogenicity of each isolate was tested against subterranean termite Coptotermes curvignathus at three concentrations of 1×106, 1×107 and 1×108 conidia mL-1. Infections of the isolates were examined using electron microscopy technique. The growth performance of each isolate differed significantly. Among all basal media, only SDAY was able to produce high growth performance and thick conidia mats with all isolates. The most pathogenic isolate was LR2, which caused 100% mortality at 1×107 conidia mL-1 within 3 days post-inoculation. Conclusion/Recommendations: All three isolates were pathogenic against C. curvignathus as they were able to germinate and penetrate into the termite cuticle within 15 hours post-inoculation. The three local isolates of M. anisopliae var. anisopliae have potential to be developed as biopesticides to control termites, C. curvignathus in oil palm plantations.

  19. Glaciochemical investigations on the subterranean ice deposit of Vukušić Ice Cave, Velebit Mountain, Croatia

    Directory of Open Access Journals (Sweden)

    Z. Kern

    2010-09-01

    Full Text Available The 3H activity, 18O/16O and 2H/1H ratio and concentration of 33 metals and metalloids have been analysed on ice core samples from the perennial subterranean cave ice deposit of Vukušić Ice Cave, Velebit Mt. The tritium data suggested that the ice deposition at 2–2.4 m depth is build from precipitation fallen ~45 years before sampling and the uppermost ice layer could be estimated between early 1970s and early 1980s or between ~1954 and 1960. Both the fluctuation range of stable water isotopes and the derived isotopic waterline of the ice agree reasonably well with the corresponding data of the local precipitation. This fact predicts that the potential of Vukušić Ice Cave's ice deposit is superior for paleoclimatological studies to the nearby Ledena Pit. Principal component analysis helped to select three groups of elements. The Ca-Mg governed group (PC1 encompasses the bedrock related components; hence the fluctuation of these elements might reflect the past intensities of the dissolution process of the adjacent epikarst. The Zn governed group (PC2 preserves probably an atmospheric deposition signal and related to the emission of regional non-ferrous metallurgy. PC3 is governed by Al and Fe. This probably carries the distal, non-karstic crustal signal hence might be related to the past atmospheric circulation (i.e. wind direction and speed.

  20. 42 CFR 435.530 - Definition of blindness.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Definition of blindness. 435.530 Section 435.530... ISLANDS, AND AMERICAN SAMOA Categorical Requirements for Eligibility Blindness § 435.530 Definition of blindness. (a) Definition. The agency must use the same definition of blindness as used under SSI,...

  1. 42 CFR 436.530 - Definition of blindness.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Definition of blindness. 436.530 Section 436.530... Requirements for Medicaid Eligibility Blindness § 436.530 Definition of blindness. (a) Definition. The agency must use the definition of blindness that is used in the State plan for AB or AABD. (b) State...

  2. Blind source separation dependent component analysis

    CERN Document Server

    Xiang, Yong; Yang, Zuyuan

    2015-01-01

    This book provides readers a complete and self-contained set of knowledge about dependent source separation, including the latest development in this field. The book gives an overview on blind source separation where three promising blind separation techniques that can tackle mutually correlated sources are presented. The book further focuses on the non-negativity based methods, the time-frequency analysis based methods, and the pre-coding based methods, respectively.

  3. New Certificateless Blind Ring Signature Scheme

    Directory of Open Access Journals (Sweden)

    Hua Sun

    2013-07-01

    Full Text Available A new certificateless blind ring signature scheme was proposed in this paper. The scheme could not only avoid the problem of certificate management of public key certificate cryptography, but also overcome the inherent key-escrow problem of identity-based public key cryptography. In the last, by using bilinear pairing technique, it was proved that this scheme satisfied the security of existential unforgeability, blindness and unconditional anonymity.

  4. Understanding display blindness in future display deployments

    OpenAIRE

    Memarovic, Nemanja; Clinch, Sarah; Alt, Florian

    2015-01-01

    Digital displays are heralded as a transformative medium for communication. However, a known challenge in the domain is that of display blindness in which passersby pay little or no attention to public displays. This phenomenon has been a major motivation for much of the research on public displays. However, since the early observations, little has been done to develop our understanding of display blindness – for example, to identify determining factors or propose appropriate metrics. Hence, ...

  5. Understanding Display Blindness in Future Display Deployments

    OpenAIRE

    Memarovic, Nemanja; Clinch, Sarah; Alt, Florian

    2015-01-01

    Digital displays are heralded as a transformative medium for communication. However, a known challenge in the domain is that of display blindness in which passersby pay little or no attention to public displays. This phenomenon has been a major motivation for much of the research on public dis- plays. However, since the early observations, little has been done to develop our understanding of display blindness – for example, to identify determining factors or propose appro- priate metrics. Hen...

  6. Haptic graphs for blind computer users

    OpenAIRE

    Yu, W; Ramloll, R.; Brewster, S.A.

    2001-01-01

    In this paper we discuss the design of computer-based haptic graphs for blind and visually impaired people with the support of our preliminary experimental results. Since visual impairment makes data visualisation techniques inappropriate for blind people, we are developing a system that can make graphs accessible through haptic and audio media. The disparity between human haptic perception and the sensation simulated by force feedback devices is discussed. Our strategies to tackle technical ...

  7. Blind Signature Scheme Based on Chebyshev Polynomials

    Directory of Open Access Journals (Sweden)

    Maheswara Rao Valluri

    2011-12-01

    Full Text Available A blind signature scheme is a cryptographic protocol to obtain a valid signature for a message from a signer such that signer’s view of the protocol can’t be linked to the resulting message signature pair. This paper presents blind signature scheme using Chebyshev polynomials. The security of the given scheme depends upon the intractability of the integer factorization problem and discrete logarithms ofChebyshev polynomials.

  8. Blind Alley Aware ACO Routing Algorithm

    Science.gov (United States)

    Yoshikawa, Masaya; Otani, Kazuo

    2010-10-01

    The routing problem is applied to various engineering fields. Many researchers study this problem. In this paper, we propose a new routing algorithm which is based on Ant Colony Optimization. The proposed algorithm introduces the tabu search mechanism to escape the blind alley. Thus, the proposed algorithm enables to find the shortest route, even if the map data contains the blind alley. Experiments using map data prove the effectiveness in comparison with Dijkstra algorithm which is the most popular conventional routing algorithm.

  9. Numerical simulation of ventilation in blinding heading

    Institute of Scientific and Technical Information of China (English)

    CHANG De-qiang; LIU Jing-xian; CHEN Bao-zhi

    2008-01-01

    The way of ventilation in all its forms and characteristics in the blinding heading was studied.On the basis of computational fluid dynamics (CFD) the turbulence model of restrained ventilation in blinding heading was set up,and the calculation boundary conditions were analyzed.According to the practice application the three-dimensional flow field of ventilation in blinding heading was simulated by the computational fluid dynamics software.The characteristics of the ventilation flow field such as the temperature field zone and the flow filed zone and the rule of the flow velocity were obtained.The ventilation in blinding heading under certain circumstances was calculated and simulated for optimization.The optimal ventilation form and related parameters under given condition were obtained.The rule of the ventilation in blinding heading was theoretical analyzed,which provided reference for the research on the process of mass transfer,the rule of hazardous substances transportation and ventilation efficiency,provided a new method for the study of reasonable and effective ventilation in blinding heading.

  10. Numerical simulation of ventilation in blinding heading

    Institute of Scientific and Technical Information of China (English)

    CHANG De-qiang; LIU Jing-xian; CHEN Bao-zhi

    2008-01-01

    The way of ventilation in all its forms and characteristics in the blinding heading was studied. On the basis of computational fluid dynamics (CFD) the turbulence model of restrained ventilation in blinding heading was set up, and the calculation boundary condi-tions were analyzed. According to the practice application the three-dimensional flow field of ventilation in blinding heading was simulated by the computational fluid dynamics soft-ware. The characteristics of the ventilation flow field such as the temperature field zone and the flow filed zone and the rule of the flow velocity were obtained. The ventilation in blinding heading under certain circumstances was calculated and simulated for optimiza-tion. The optimal ventilation form and related parameters under given condition were ob-tained. The rule of the ventilation in blinding heading was theoretical analyzed, which pro-vided reference for the research on the process of mass transfer, the rule of hazardous substances transportation and ventilation efficiency, provided a new method for the study of reasonable and effective ventilation in blinding heading.

  11. The Prevention of Blindness-Past, Present and Future

    Institute of Scientific and Technical Information of China (English)

    Akira; Nakajima

    1992-01-01

    Prevention of blindness is the most important aim of ophthalmology. Prevention of blindness is related to many factors. It is related to many factors, such as science and technology, economy and social behavior. There are worldwide activities by WHO, NGOs and other functions to promote the prevention of blindness in the world. More than 90% of blind population lives in developing world. Cataract is the top causes of blindness which is curable. Onchocerciasis is an endemic disease in west Africa and cent...

  12. CORTICAL REPRESENTATION OF SPACE AROUND THE BLIND SPOT

    OpenAIRE

    Awater, Holger; Kerlin, Jess R.; Evans, Karla K.; Tong, Frank

    2005-01-01

    The neural mechanism that mediates perceptual filling-in of the blind spot is still under discussion. One hypothesis proposes that the cortical representation of the blind spot is activated only under conditions that elicit perceptual filling-in, and requires congruent stimulation on both sides of the blind spot. Alternatively, the passive remapping hypothesis proposes that inputs from regions surrounding the blind spot infiltrate the representation of the blind spot in cortex. This theory pr...

  13. The Blinds Shop Company Limited Brand Identity Project

    OpenAIRE

    Dee, Peter

    2008-01-01

    The Blinds Shop offers made to measure window blinds catering to all markets across Ireland. The Blinds Shop required a clean, bold and modern logo using fresh colours and imagery. Peter Dee - Strategic Design and Marketing Consultant, was responsible for the design and development of the brand identity for the The Blinds Shop Company Limited which was used on business cards, letterhead, promotional information, uniforms, advertising and e-Commerce website. The Blinds Shop is a retailer...

  14. Blindness and severe visual impairment in pupils at schools for the blind in Burundi

    Directory of Open Access Journals (Sweden)

    Patrick Ruhagaze

    2013-01-01

    Full Text Available Purpose: To determine the causes of childhood blindness and severe visual impairment in pupils attending schools for the blind in Burundi in order to assist planning for services in the country. Materials and Methods: All pupils attending three schools for the blind in Burundi were examined. A modified WHO/PBL eye examination record form for children with blindness and low vision was used to record the findings. Data was analyzed for those who became blind or severely visually impaired before the age of 16 years. Results: Overall, 117 pupils who became visually impaired before 16 years of age were examined. Of these, 109 (93.2% were blind or severely visually impaired. The major anatomical cause of blindness or severe visual impairment was cornea pathology/phthisis (23.9%, followed by lens pathology (18.3%, uveal lesions (14.7% and optic nerve lesions (11.9%. In the majority of pupils with blindness or severe visual impairment, the underlying etiology of visual loss was unknown (74.3%. More than half of the pupils with lens related blindness had not had surgery; among those who had surgery, outcomes were generally poor. Conclusion: The causes identified indicate the importance of continuing preventive public health strategies, as well as the development of specialist pediatric ophthalmic services in the management of childhood blindness in Burundi. The geographic distribution of pupils at the schools for the blind indicates a need for community-based programs to identify and refer children in need of services.

  15. Environmental physiology of the mole crab Emerita asiatica, at a power plant discharge area on the east coast of India

    International Nuclear Information System (INIS)

    Cage experiments at the discharge area of Madras Atomic Power Station (MAPS) facilitated studies of thermal tolerance in Emerita asiatica. At the laboratory, oxygen consumption at various temperatures and varying salinities was also investigated. In the field 100% mortality of crabs was recorded at the Condenser Cooling Water Pumps (CCWP) discharge site compared to no mortality at the Processed Sea Water Pumps (PSWP) site. This observation implicated temperature as a stress factor at the CCWP outfall, because other factors, including residual chlorine and water velocity, were the same at the PSWP and CCWP sites. Laboratory experiments on tolerance revealed that 38.5oC was lethal to mole crabs. The time taken for 100% mortality decreased as the temperature increased from 35 to 40oC. Oxygen metabolism showed a progressive increase with temperature from 29 to 36oc, and declined at 37oC. The influence of salinity on oxygen consumption was marginal at salinities of 20 to 35o/oo but, when reduced to 15o/oo, the oxygen consumption declined. The present study thus indicates that temperature could be the lethal factor, determining the distribution of mole crabs near the power station, where water temperature can exceed 40oC. (author)

  16. Development of traceable precision dynamic dilution method to generate dimethyl sulphide gas mixtures at sub-nanomole per mole levels for ambient measurement.

    Science.gov (United States)

    Kim, Mi Eon; Kim, Yong Doo; Kang, Ji Hwan; Heo, Gwi Suk; Lee, Dong Soo; Lee, Sangil

    2016-04-01

    Dimethyl sulphide (DMS) is an important compound in global atmospheric chemistry and climate change. Traceable international standards are essential for measuring accurately the long-term global trend in ambient DMS. However, developing accurate gas standards for sub-nanomole per mole (nmol/mol) mole fractions of DMS in a cylinder is challenging, because DMS is reactive and unstable. In this study, a dynamic dilution method that is traceable and precise was developed to generate sub-nmol/mol DMS gas mixtures with a dynamic dilution system based on sonic nozzles and a long-term (>5 years) stable 10 μmol/mol parent DMS primary standard gas mixtures (PSMs). The dynamic dilution system was calibrated with traceable methane PSMs, and its estimated dilution factors were used to calculate the mole fractions of the dynamically generated DMS gas mixtures. A dynamically generated DMS gas mixture and a 6 nmol/mol DMS PSM were analysed against each other by gas chromatography with flame-ionisation detection (GC/FID) to evaluate the dilution system. The mole fractions of the dynamically generated DMS gas mixture determined against a DMS PSM and calculated with the dilution factor agreed within 1% at 6 nmol/mol. In addition, the dynamically generated DMS gas mixtures at various mole fractions between 0.4 and 11.7 nmol/mol were analysed by GC/FID and evaluated for their linearity. The analytically determined mole fractions showed good linearity with the mole fractions calculated with the dilution factors. Results showed that the dynamic dilution method generates DMS gas mixtures ranging between 0.4 nmol/mol and 12 nmol/mol with relative expanded uncertainties of less than 2%. Therefore, the newly developed dynamic dilution method is a promising reference method for generating sub-nmol/mol DMS gas standards for accurate ambient measurements. PMID:26838438

  17. Tactile Sensitivity and Braille Reading in People with Early Blindness and Late Blindness

    Science.gov (United States)

    Oshima, Kensuke; Arai, Tetsuya; Ichihara, Shigeru; Nakano, Yasushi

    2014-01-01

    Introduction: The inability to read quickly can be a disadvantage throughout life. This study focused on the associations of braille reading fluency and individual factors, such as the age at onset of blindness and number of years reading braille, and the tactile sensitivity of people with early and late blindness. The relationship between reading…

  18. Genetically Engineered Yeast Expressing a Lytic Peptide from Bee Venom (Melittin Kills Symbiotic Protozoa in the Gut of Formosan Subterranean Termites.

    Directory of Open Access Journals (Sweden)

    Claudia Husseneder

    Full Text Available The Formosan subterranean termite, Coptotermes formosanus Shiraki, is a costly invasive urban pest in warm and humid regions around the world. Feeding workers of the Formosan subterranean termite genetically engineered yeast strains that express synthetic protozoacidal lytic peptides has been shown to kill the cellulose digesting termite gut protozoa, which results in death of the termite colony. In this study, we tested if Melittin, a natural lytic peptide from bee venom, could be delivered into the termite gut via genetically engineered yeast and if the expressed Melittin killed termites via lysis of symbiotic protozoa in the gut of termite workers and/or destruction of the gut tissue itself. Melittin expressing yeast did kill protozoa in the termite gut within 56 days of exposure. The expressed Melittin weakened the gut but did not add a synergistic effect to the protozoacidal action by gut necrosis. While Melittin could be applied for termite control via killing the cellulose-digesting protozoa in the termite gut, it is unlikely to be useful as a standalone product to control insects that do not rely on symbiotic protozoa for survival.

  19. Genetically Engineered Yeast Expressing a Lytic Peptide from Bee Venom (Melittin) Kills Symbiotic Protozoa in the Gut of Formosan Subterranean Termites.

    Science.gov (United States)

    Husseneder, Claudia; Donaldson, Jennifer R; Foil, Lane D

    2016-01-01

    The Formosan subterranean termite, Coptotermes formosanus Shiraki, is a costly invasive urban pest in warm and humid regions around the world. Feeding workers of the Formosan subterranean termite genetically engineered yeast strains that express synthetic protozoacidal lytic peptides has been shown to kill the cellulose digesting termite gut protozoa, which results in death of the termite colony. In this study, we tested if Melittin, a natural lytic peptide from bee venom, could be delivered into the termite gut via genetically engineered yeast and if the expressed Melittin killed termites via lysis of symbiotic protozoa in the gut of termite workers and/or destruction of the gut tissue itself. Melittin expressing yeast did kill protozoa in the termite gut within 56 days of exposure. The expressed Melittin weakened the gut but did not add a synergistic effect to the protozoacidal action by gut necrosis. While Melittin could be applied for termite control via killing the cellulose-digesting protozoa in the termite gut, it is unlikely to be useful as a standalone product to control insects that do not rely on symbiotic protozoa for survival. PMID:26985663

  20. Turning the tide of corneal blindness

    Directory of Open Access Journals (Sweden)

    Matthew S Oliva

    2012-01-01

    Full Text Available Corneal diseases represent the second leading cause of blindness in most developing world countries. Worldwide, major investments in public health infrastructure and primary eye care services have built a strong foundation for preventing future corneal blindness. However, there are an estimated 4.9 million bilaterally corneal blind persons worldwide who could potentially have their sight restored through corneal transplantation. Traditionally, barriers to increased corneal transplantation have been daunting, with limited tissue availability and lack of trained corneal surgeons making widespread keratoplasty services cost prohibitive and logistically unfeasible. The ascendancy of cataract surgical rates and more robust eye care infrastructure of several Asian and African countries now provide a solid base from which to dramatically expand corneal transplantation rates. India emerges as a clear global priority as it has the world′s largest corneal blind population and strong infrastructural readiness to rapidly scale its keratoplasty numbers. Technological modernization of the eye bank infrastructure must follow suit. Two key factors are the development of professional eye bank managers and the establishment of Hospital Cornea Recovery Programs. Recent adaptation of these modern eye banking models in India have led to corresponding high growth rates in the procurement of transplantable tissues, improved utilization rates, operating efficiency realization, and increased financial sustainability. The widespread adaptation of lamellar keratoplasty techniques also holds promise to improve corneal transplant success rates. The global ophthalmic community is now poised to scale up widespread access to corneal transplantation to meet the needs of the millions who are currently blind.

  1. Turning the tide of corneal blindness.

    Science.gov (United States)

    Oliva, Matthew S; Schottman, Tim; Gulati, Manoj

    2012-01-01

    Corneal diseases represent the second leading cause of blindness in most developing world countries. Worldwide, major investments in public health infrastructure and primary eye care services have built a strong foundation for preventing future corneal blindness. However, there are an estimated 4.9 million bilaterally corneal blind persons worldwide who could potentially have their sight restored through corneal transplantation. Traditionally, barriers to increased corneal transplantation have been daunting, with limited tissue availability and lack of trained corneal surgeons making widespread keratoplasty services cost prohibitive and logistically unfeasible. The ascendancy of cataract surgical rates and more robust eye care infrastructure of several Asian and African countries now provide a solid base from which to dramatically expand corneal transplantation rates. India emerges as a clear global priority as it has the world's largest corneal blind population and strong infrastructural readiness to rapidly scale its keratoplasty numbers. Technological modernization of the eye bank infrastructure must follow suit. Two key factors are the development of professional eye bank managers and the establishment of Hospital Cornea Recovery Programs. Recent adaptation of these modern eye banking models in India have led to corresponding high growth rates in the procurement of transplantable tissues, improved utilization rates, operating efficiency realization, and increased financial sustainability. The widespread adaptation of lamellar keratoplasty techniques also holds promise to improve corneal transplant success rates. The global ophthalmic community is now poised to scale up widespread access to corneal transplantation to meet the needs of the millions who are currently blind. PMID:22944753

  2. Hypersensitivity to pain in congenital blindness

    DEFF Research Database (Denmark)

    Slimani, Hocine; Danti, Sabrina; Ricciardi, Emiliano;

    2013-01-01

    responses to suprathreshold heat stimuli in 2 groups of congenitally blind and matched normal-sighted participants. We also assessed detection thresholds for innocuous warmth and cold, and participants' attitude toward painful encounters in daily life. Our results show that, compared to sighted subjects......, congenitally blind subjects have lower heat pain thresholds, rate suprathreshold heat pain stimuli as more painful, and have increased sensitivity for cold pain stimuli. Thresholds for nonpainful thermal stimulation did not differ between groups. The results of the pain questionnaires further indicated that...... blind subjects are more attentive to signals of external threats. These findings indicate that the absence of vision from birth induces a hypersensitivity to painful stimuli, lending new support to a model of sensory integration of vision and pain processing....

  3. Blindness and cataract in children in developing countries

    Directory of Open Access Journals (Sweden)

    Parikshit Gogate

    2009-03-01

    Full Text Available Blindness in children is considered a priority area for VISION 2020, as visually impaired children have a lifetime of blindness ahead of them. Various studies across the globe show that one-third to half of childhood blindness is either preventable or treatable1 and that cataract is the leading treatable cause of blindness in children.The 8th General Assembly of the International Agency for the Prevention of Blindness (IAPB provided an opportunity to be acquainted with recent research and programme development work in the prevention of childhood blindness.

  4. Acute onset of severe hemolysis, elevated liver enzymes, and low platelet count syndrome in a patient with a partial hydatidiform mole at 17 weeks gestation.

    Science.gov (United States)

    Sherer, David M; Dalloul, Mudar; Stimphil, Raphael; Hellmann, Mira; Khoury-Collado, Fady; Osho, Joseph; Fomitcheva, Larissa; Brennan, Kelly J; Abulafia, Ovadia

    2006-04-01

    Preeclampsia is uncommon prior to 24 weeks gestation and has been associated with partial and complete hydatidiform moles. We present an unusual case in which a patient was diagnosed with preeclampsia at 17 weeks gestation. Ultrasound findings were consistent with a partial hydatidiform mole. Within 24 hours of the onset of symptoms, the patient developed severe hemolysis, elevated liver enzymes, and low platelet count syndrome, with a platelet count of 20 x 10 (9) cells/L. Termination of pregnancy was performed with rapid resolution of signs, symptoms, and laboratory abnormalities. Triploid 69,XXY was confirmed at karyotype analysis. This case demonstrates the acuteness in which life-threatening maternal conditions can arise with this uncommon complication of pregnancy, and the importance of correct identification of the characteristic ultrasonographic findings associated with a partial hydatidiform mole. PMID:16586230

  5. 30Si Mole Fraction of a Silicon Material Highly Enriched in 28Si Determined by Instrumental Neutron Activation Analysis

    CERN Document Server

    D'Agostino, Giancarlo; Mana, Giovanni; Oddone, Massimo; Pramann, Axel; Prata, Michele

    2016-01-01

    The latest determination of the Avogadro constant, carried out by counting the atoms in a pure silicon crystal highly enriched in 28Si, reached the target 2x10-8 relative uncertainty required for the redefinition of the kilogram based on the Planck constant. The knowledge of the isotopic composition of the enriched silicon material is central; it is measured by isotope dilution mass spectrometry. In this work, an independent estimate of the 30Si mole fraction was obtained by applying a relative measurement protocol based on Instrumental Neutron Activation Analysis. The amount of 30Si isotope was determined by counting the 1266.1 keV gamma-photons emitted during the radioactive decay of the radioisotope 31Si produced via the neutron capture reaction 30Si(n,gamma)31Si. The x(30Si) = 1.043(19)x10-6 mol mol-1 is consistent with the value currently adopted by the International Avogadro Coordination.

  6. Comment on a mathematical model for estimating biological damage caused by radiation. Whack-A-Mole model

    International Nuclear Information System (INIS)

    We propose a mathematical model, Whack-A-Mole (WAM) model which can estimate the biological effect caused by radiation. The WAM model assumes that the basic element is a cell and the number of cells increases or decreases due to response to stimulus, damage and recovery, cause by radiation and so on. WAM takes into account dose rate as an important physical quantity, which marks a fundamental difference from target theory or LQ model. WAM model reproduces various experimental data of mutation frequency induced by radiation, for example, mega-mouse project. Furthermore, we can predict unknown experimental results. From WAM model, it is learnt that the mutation frequency caused by radiation is not proportional to dose but also have saturation value. There is some possibility that the WAM model will drastically change risk estimation of radiation as it brings us different results from those of target theory or LQ model. (author)

  7. Blind source separation theory and applications

    CERN Document Server

    Yu, Xianchuan; Xu, Jindong

    2013-01-01

    A systematic exploration of both classic and contemporary algorithms in blind source separation with practical case studies    The book presents an overview of Blind Source Separation, a relatively new signal processing method.  Due to the multidisciplinary nature of the subject, the book has been written so as to appeal to an audience from very different backgrounds. Basic mathematical skills (e.g. on matrix algebra and foundations of probability theory) are essential in order to understand the algorithms, although the book is written in an introductory, accessible style. This book offers

  8. Multichannel Blind Deconvolution in Eye Fundus Imaging

    Czech Academy of Sciences Publication Activity Database

    Marrugo, A.; Šorel, Michal; Šroubek, Filip; Millán, M. S.

    Barcelona: ACM, 2011, s. 1-4. ISBN 978-1-4503-0913-4. [4th International Symposium on Applied Sciences in Biomedical and Communication Technologies. Barcelona (ES), 26.10.2011-29.10.2011] R&D Projects: GA MŠk 1M0572 Institutional research plan: CEZ:AV0Z10750506 Keywords : blind deconvolution * fundus image * medical image Subject RIV: JD - Computer Applications, Robotics http://library.utia.cas.cz/separaty/2012/ZOI/sroubek-multichannel blind deconvolution in eye fundus imaging.pdf

  9. Management of a blind painful eye.

    Science.gov (United States)

    Merbs, Shannath L

    2006-06-01

    Debilitating ocular pain poses a significant challenge to the ophthalmologist. When the pain is intractable and the eye has very poor vision and is disfigured, surgical removal of the eye has traditionally been the definitive treatment of choice. Because many people are uncomfortable psychologically with removal of their eye, however painful, and other patients are not good surgical candidates, an alternative to enucleation is sometimes warranted, and injection of a neurolytic substance can often induce long-lasting anesthesia for a blind painful eye. This article reviews a range of options for management of blind painful eye from anesthesia to enucleation. PMID:16701166

  10. Transform domain steganography with blind source separation

    Science.gov (United States)

    Jouny, Ismail

    2015-05-01

    This paper applies blind source separation or independent component analysis for images that may contain mixtures of text, audio, or other images for steganography purposes. The paper focuses on separating mixtures in the transform domain such as Fourier domain or the Wavelet domain. The study addresses the effectiveness of steganography when using linear mixtures of multimedia components and the ability of standard blind sources separation techniques to discern hidden multimedia messages. Mixing in the space, frequency, and wavelet (scale) domains is compared. Effectiveness is measured using mean square error rate between original and recovered images.

  11. Spatial and temporal activity patterns of the free-living giant mole-rat (Fukomys mechowii, the largest social bathyergid.

    Directory of Open Access Journals (Sweden)

    Matěj Lövy

    Full Text Available Despite the considerable attention devoted to the biology of social species of African mole-rats (Bathyergidae, Rodentia, knowledge is lacking about their behaviour under natural conditions. We studied activity of the largest social bathyergid, the giant mole-rat Fukomys mechowii, in its natural habitat in Zambia using radio-telemetry. We radio-tracked six individuals during three continuous 72-h sessions. Five of these individuals, including a breeding male, belonged to a single family group; the remaining female was probably a solitary disperser. The non-breeders of the family were active (i.e. outside the nest 5.8 hours per 24h-day with the activity split into 6.5 short bouts. The activity was more concentrated in the night hours, when the animals also travelled longer distances from the nest. The breeding male spent only 3.2 hours per day outside the nest, utilizing less than 20% of the whole family home range. The dispersing female displayed a much different activity pattern than the family members. Her 8.0 hours of outside-nest activity per day were split into 4.6 bouts which were twice as long as in the family non-breeders. Her activity peak in the late afternoon coincided with the temperature maximum in the depth of 10 cm (roughly the depth of the foraging tunnels. Our results suggest that the breeding individuals (at least males contribute very little to the work of the family group. Nevertheless, the amount of an individual's activity and its daily pattern are probably flexible in this species and can be modified in response to actual environmental and social conditions.

  12. Reactive scattering of halogen molecules. [Angular and velocity distributions, stabilities 6. 8 to 17. 7 kcal/mole, FORTRAN

    Energy Technology Data Exchange (ETDEWEB)

    Valentini, J.J.

    1976-11-01

    A study of the endoergic, bimolecular reactions of F/sub 2/ with I/sub 2/, ICl, and HI in a crossed molecular beam experiment is described. The trihalogens IIF, ClIF, and HIF were directly observed as the products of these reactions. At high collision energies a second reactive channel producing IF becomes important. Product angular and velocity distributions show that this IF does not result from a four-center exchange reaction. Measured threshold energies for the formation of IIF, ClIF, and HIF yield lower bounds to the stabilities of these molecules, with respect to the separated atoms, of 69, 81, and 96 kcal/mole, respectively. Analysis of product center-of-mass angular distributions indicates that a slightly nonlinear approach is most effective in bringing about reaction to form the stable triatomic radical. Also described is a crossed molecular beam study of the Cl + Br/sub 2/ ..-->.. BrCl + Br reaction at collision energies from 6.8 to 17.7 kcal/mole. The results indicate that this reaction has the characteristics of an exoergic reaction on an attractive potential energy surface with early energy release. Reagent translational energy is very efficiently channeled into product internal energy. At high collision energy the reaction appears to approach the spectator stripping limit. Finally, a series of computer programs which can be used to carry out the requisite data analysis for crossed molecular beam reactive scattering experiments are described. These programs recover the reactive scattering center-of-mass flux distribution from the measured angular and velocity distributions of the products.

  13. Immunohistochemical Analysis of E-Cadherin, p53 and Inhibin-α Expression in Hydatidiform Mole and Hydropic Abortion.

    Science.gov (United States)

    Erol, Onur; Süren, Dinç; Tutuş, Birsel; Toptaş, Tayfun; Gökay, Ahmet Arda; Derbent, Aysel Uysal; Özel, Mustafa Kemal; Sezer, Cem

    2016-07-01

    The purpose of this study was to investigate the role of E-cadherin, p53, and inhibin-α immunostaining in the differential diagnosis of hydropic abortion (HA), partial hydatidiform mole (PHM), and complete hydatidiform mole (CHM). E-cadherin, p53, and inhibin-α protein expression patterns were investigated immunohistochemically using paraffin -embedded tissue sections from histologically diagnosed cases of HA (n = 23), PHM (n = 24), and CHM (n = 23). Expression patterns of these markers were scored semi-quantitatively according to the staining intensity, percentage of positive cells, and immunoreactivity score. Classification of cases was established on histologic criteria and supported by the molecular genotyping. Immunostaining allowed the identification of specific cell types with E-cadherin, p53, and inhibin-α expression in all cases. E-cadherin expression was detected on the cell surface of villous cytotrophoblasts. We observed a marked decline in the expression of E-cadherin from HAs to PHMs to CHMs. The p53-positive reaction was restricted to the nucleus of villous cytotrophoblasts. Significantly increased p53 expression was observed in CHMs, compared with HAs and PHMs. The expression of inhibin-α was localised in the cytoplasm of villous syncytiotrophoblasts, and the expression of this marker was significantly higher in PHMs and CHMs than HAs. In conclusion, immunohistochemical analysis of E-cadherin, p53, and inhibin-α expression could serve as a useful adjunct to conventional methods in the differential diagnosis of HA, PHM, and CHM. PMID:26683836

  14. The Mars Underground Mole (MUM): A Subsurface Penetration Device with Infrared Reflectance and Raman Spectroscopic Sensing Capability

    Science.gov (United States)

    Stoker, C. R.; Richter, L.; Smith, W. H.; Lemke, L. G.; Hammer, P.; Dalton, J. B.; Glass, B.; Zent, A.

    2003-01-01

    Searching for evidence of life on Mars will probably require access to the subsurface. The Martian surface is bathed in ultraviolet radiation which decomposes organic compounds, destroying possible evidence for life. Also, experiments performed by the Viking Landers imply the presence of several strongly oxidizing compounds at the Martian surface that may also play a role in destroying organic compounds near the surface. While liquid water is unstable on the Martian surface, and ice is unstable at the surface at low latitudes, recent results from the Mars Odyssey Gamma Ray Spectrometer experiment indicate that water ice is widely distributed near the surface under a thin cover of dry soil. Organic compounds created by an ancient Martian biosphere might be preserved in such ice-rich layers. Furthermore, accessing the subsurface provides a way to identify unique stratigraphy such as small-scale layering associated with lacustrine sediments. Subsurface access might also provide new insights into the Mars climate record that may be preserved in the Polar Layered Deposits. Recognizing the importance of accessing the subsurface of Mars to the future scientific exploration of the planet, the Mars Surveyor 2007 Science Definition Team called for drilling beneath the surface soils. Subsurface measurements are also cited as high priority in by MEPAG. Recognizing the importance of accessing the Martian subsurface to search for life, the European Space Agency has incorporated a small automated burrowing device called a subsurface penetrometer or Mole onto the Beagle 2 lander planned for 2003 launch. This device, called the Planetary Underground Tool (PLUTO), is a pointed slender cylinder 2 cm wide and 28 cm long equipped with a small sampling device at the pointed end that collects samples and brings them to the surface for analysis. Drawing on the PLUTO design, we are developing a larger Mole carrying sensors for identifying mineralogy, organic compounds, and water.

  15. Subcaste differences in neural activation suggest a prosocial role for oxytocin in eusocial naked mole-rats.

    Science.gov (United States)

    Hathaway, Georgia A; Faykoo-Martinez, Mariela; Peragine, Deane E; Mooney, Skyler J; Holmes, Melissa M

    2016-03-01

    The neuropeptide oxytocin (OT) influences prosocial behavior(s), aggression, and stress responsiveness, and these diverse effects are regulated in a species- and context-specific manner. The naked mole-rat (Heterocephalus glaber) is a unique species with which to study context-dependent effects of OT, exhibiting a strict social hierarchy with behavioral specialization within the subordinate caste: soldiers are aggressive and defend colonies against unfamiliar conspecifics while workers are prosocial and contribute to in-colony behaviors such as pup care. To determine if OT is involved in subcaste-specific behaviors, we compared behavioral responses between workers and soldiers of both sexes during a modified resident/intruder paradigm, and quantified activation of OT neurons in the hypothalamic paraventricular nucleus (PVN) and supraoptic nucleus (SON) using the immediate-early-gene marker c-fos co-localized with OT neurons. Resident workers and soldiers were age-matched with unfamiliar worker stimulus animals as intruders, and encounters were videorecorded and scored for aggressive behaviors. Colony-matched controls were left in their home colony for the duration of the encounters. Brains were extracted and cell counts were conducted for OT immunoreactive (ir), c-fos-ir, and percentage of OT-c-fos double-labeled cells. Results indicate that resident workers were less aggressive but showed greater OT neural activity than soldiers. Furthermore, a linear model including social treatment, cortisol, and subcaste revealed that subcaste was the only significant predictor of OT-c-fos double-labeled cells in the PVN. These data suggest that in naked mole-rats OT promotes prosocial behaviors rather than aggression and that even within subordinates status exerts robust effects on brain and behavior. PMID:26718226

  16. Response of mole crab, Emerita emeritus to the thermal effluents from the Madras Atomic Power Station at Kalpakkam

    International Nuclear Information System (INIS)

    Mole crabs belonging to the genus Emerita are exclusively inhabitants of exposed wave washed sandy beaches in certain temperate and tropical seas. Its sedentary adult life and a primitive filter-feeding behavior make this intertidal crab an excellent indicator species for monitoring anthropogenic impact. Hence, this sand crab has been used to determine the effect of elevated temperature (rT) arising out of the thermal effluent from the Madras Atomic Power Station (MAPS), Kalpakkam with special reference to the intertidal fauna. Since Emerita exhibits limited capacity to move from their place of habitation, an analysis of the population structure of Emerita emeritus in the Kalpakkam coast including the impacted and the adjoining control sandy beaches on either side of the mixing point in the vicinity of the power plant was done. The data indicate that in the impact zone having an elevated seawater temperature of <35 deg C, the crab is completely absent. However, as we move away from the impact zone, with normalization of seawater temperature, Emerita move to safer areas on either side of the impact zone. Thus, the extensive field data on the distribution of mole crabs indicated that population structure is affected by the thermal plume, although the shifting positions of the mixing point (caused by northerly and southerly long shore currents) allowed decolonization of Emerita due to transmigration in positions that were earlier mixing points. This paper also describes a complete larval development of Emerita emeritus in the laboratory. Different life stages of E. emeritus were subjected to various power plant stressors to determine their varying responses. The expression of heat shock protein (hsp) in the gill tissue of the adult crabs was also observed when the crabs were exposed to elevated temperatures (35 deg C). However, no expression of heat shock proteins was observed when the crabs were subjected to chlorine stress. (author)

  17. Metabolic clues to salubrious longevity in the brain of the longest-lived rodent: the naked mole-rat.

    Science.gov (United States)

    Triplett, Judy C; Swomley, Aaron; Kirk, Jessime; Lewis, Katilyn; Orr, Miranda; Rodriguez, Karl; Cai, Jian; Klein, Jon B; Buffenstein, Rochelle; Butterfield, D Allan

    2015-08-01

    Naked mole-rats (NMRs) are the oldest-living rodent species. Living underground in a thermally stable ecological niche, NMRs have evolved certain exceptional traits, resulting in sustained health spans, negligible cognitive decline, and a pronounced resistance to age-related disease. Uncovering insights into mechanisms underlying these extraordinary traits involved in successful aging may conceivably provide crucial clues to extend the human life span and health span. One of the most fundamental processes inside the cell is the production of ATP, which is an essential fuel in driving all other energy-requiring cellular activities. Not surprisingly, a prominent hallmark in age-related diseases, such as neurodegeneration and cancer, is the impairment and dysregulation of metabolic pathways. Using a two-dimensional polyacrylamide gel electrophoresis proteomics approach, alterations in expression and phosphorylation levels of metabolic proteins in the brains of NMRs, aged 2-24 years, were evaluated in an age-dependent manner. We identified 13 proteins with altered levels and/or phosphorylation states that play key roles in various metabolic pathways including glycolysis, β-oxidation, the malate-aspartate shuttle, the Tricarboxylic Acid Cycle (TCA) cycle, the electron transport chain, NADPH production, as well as the production of glutamate. New insights into potential pathways involved in metabolic aspects of successful aging have been obtained by the identification of key proteins through which the NMR brain responds and adapts to the aging process and how the NMR brain adapted to resist age-related degeneration. This study examines the changes in the proteome and phosphoproteome in the brain of the naked mole-rat aged 2-24 years. We identified 13 proteins (labeled in red) with altered expression and/or phosphorylation levels that are conceivably associated with sustained metabolic functions in the oldest NMRs that may promote a sustained health span and life span

  18. From Performance Optimization to Simulation-based Forensic Engineering - An extensive Approach for Dynamic Modeling of the HP³-Mole for InSight

    OpenAIRE

    Lichtenheldt, Roy

    2015-01-01

    In order to enable the InSight’s investigations of the Martian interior, the HP³-Mole has to hammer itself deeper below the surface of the red planet, than any other instrument before. In order to achieve this challenging goal, the dynamics of the impact driven locomotion as well as the mutual influence between the stroke cycle and the regolith need to be well understood. However it is not possible to observe the complex mechanism behaviour while the HP³-Mole is operating in Martian soil or t...

  19. Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

    DEFF Research Database (Denmark)

    Jørgensen, Kristine B.; Krogh-Jensen, Karen; Pickering, Darryl S;

    2016-01-01

    musculus) using basic local alignment search tool (BLAST). The presence and function of M1 and M4 was investigated in vivo, using the formalin test with the muscarinic receptor agonists xanomeline and VU0152100. Spinal cord tissue from the naked mole-rat was used for receptor saturation binding studies...... with [3H]-N-methylscopolamine. The BLAST test revealed 95 % protein sequence homology showing the naked mole-rat to have the genetic potential to express all five muscarinic acetylcholine receptor subtypes. A significant reduction in pain behavior was demonstrated after administration of 8.4 mg/kg in...

  20. INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform

    OpenAIRE

    Tian, Xiao; Azpurua, Jorge; Ke, Zhonghe; Augereau, Adeline; Zhang, Zhengdong D.; Vijg, Jan; Gladyshev, Vadim N; Gorbunova, Vera; Seluanov, Andrei

    2014-01-01

    The naked mole rat is a longest lived and cancer-resistant rodent. Tumor resistance in the naked mole rat is mediated by signals from the extracellular matrix component hyaluronan triggering the induction of INK4 (inhibitors of cyclin dependent kinase 4) locus expression. The human and mouse INK4 locus encodes three critical tumor-suppressor proteins, p15INK4b, ARF (alternate reading frame), and p16INK4a, which are among the most frequently mutated in cancer. Furthermore, p16INK4a is implicat...

  1. Leading Causes of Blindness | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... turn Javascript on. Feature: Vision Leading Causes of Blindness Past Issues / Winter 2012 Table of Contents Cataract ... have cataracts. They are the leading cause of blindness in the world. By age 80, more than ...

  2. Experimental Contact Lens to Prevent Glaucoma-Induced Blindness

    Science.gov (United States)

    ... An Experimental Contact Lens to Prevent Glaucoma-Induced Blindness By Sharon Reynolds Posted January 23, 2014 An ... group of conditions that can result in irreversible blindness. This vision loss can be reduced if glaucoma ...

  3. Research on solar-blind UV optical imaging system

    Science.gov (United States)

    Wang, Baohua; Wang, Yuanyuan; Zhong, Xiaoming; Ruan, Ningjuan

    2015-02-01

    Solar blind UV detecting system has many advantages such as strong environmental adaptability, low error rate, small volume and without refrigeration. To in-depth develop UV solar blind detection system research work has important significance for further improving solar blind UV detection technology. The working principle of solar blind UV detection system and the basic components were introduced firstly, and then the key technology of solar blind UV detection system was deeply analyzed. Finally, large coverage solar blind UV optical imaging system was designed according to the actual demand for greater coverage of the solar blind UV detection system. The result shows that the system has good imaging quality, simple and compact structure. This system can be used in various types of solar blind UV detection system, and is of high application value.

  4. Find Services for People Who Are Blind or Visually Impaired

    Science.gov (United States)

    ... Find Services for People Who Are Blind or Visually Impaired Category All Advocacy Assessment/Evaluation Audio, Braille or ... Find Services for People Who Are Blind or Visually Impaired Browse All Search Categories About the Directory Request ...

  5. Warming Endotracheal Tube in Blind Nasotracheal Intubation throughout Maxillofacial Surgeries

    Directory of Open Access Journals (Sweden)

    Hamzeh Hosseinzadeh

    2013-12-01

    Conclusion: In conclusion, our study showed that using an endotracheal tube softened by warm water could reduce the incidence and severity of epistaxis during blind nasotracheal intubation; however it could not facilitate blind nasotracheal intubation.

  6. If I am Blind or Deaf

    Institute of Scientific and Technical Information of China (English)

    李新颖

    2005-01-01

    For some time,l wished to be blind or deaf so that I could avoid the sight or the sound from having driven me mad.The majority of people must object the idea that the dark life maybe more beautiful than the life full of limitations and unhappiness.

  7. Usage of Blinds Software in Libraries

    OpenAIRE

    Fatema El Zahraa Mohamed Abdou

    2006-01-01

    The research reviews some of blinds software used in libraries, it reviews the following software : JAWS, Zoomtext, Kurzuail. Then deals the services offered by the software in libraries, these services are : pronouncing the written texts, printing in Brail method, educational software for computer, browsing the internet, and enlarging texts on the screen.

  8. CI-TAB: View for the Blind.

    Science.gov (United States)

    Abrams, Ken

    1979-01-01

    The article describes the development and content of a comprehensive career education program for blind elementary and secondary students. Eight areas are explored in the program: job search skills, job behavior, hygiene and grooming, purchase habits, budgeting, banking, home management, and health care. (CL)

  9. A blind test of photometric redshift prediction

    OpenAIRE

    Hogg, David W.; Cohen, Judith G.; Blandford, Roger; Gwyn, Stephen D. J.; Hartwick, F. D. A.; Mobasher, B.; Mazzei, Paula; Sawicki, Marcin; Lin, Huan; Yee, H. K. C.; Connolly, Andrew J; Brunner, Robert J.; Csabai, Istvan; Dickinson, Mark; SubbaRao, Mark U.

    1998-01-01

    Results of a blind test of photometric redshift predictions against spectroscopic galaxy redshifts obtained in the Hubble Deep Field with the Keck Telescope are presented. The best photometric redshift schemes predict spectroscopic redshifts with a redshift accuracy of |Delta-z|

  10. Recruitment, Retention, and Blinding in Clinical Trials

    OpenAIRE

    Page, Stephen J.; Persch, Andrew C.

    2013-01-01

    The recruitment and retention of participants and the blinding of participants, health care providers, and data collectors present challenges for clinical trial investigators. This article reviews challenges and alternative strategies associated with these three important clinical trial activities. Common recruiting pitfalls, including low sample size, unfriendly study designs, suboptimal testing locations, and untimely recruitment are discussed together with strategies for overcoming these b...

  11. Blind Quantum Computing with Weak Coherent Pulses

    Science.gov (United States)

    Dunjko, Vedran; Kashefi, Elham; Leverrier, Anthony

    2012-05-01

    The universal blind quantum computation (UBQC) protocol [A. Broadbent, J. Fitzsimons, and E. Kashefi, in Proceedings of the 50th Annual IEEE Symposiumon Foundations of Computer Science (IEEE Computer Society, Los Alamitos, CA, USA, 2009), pp. 517-526.] allows a client to perform quantum computation on a remote server. In an ideal setting, perfect privacy is guaranteed if the client is capable of producing specific, randomly chosen single qubit states. While from a theoretical point of view, this may constitute the lowest possible quantum requirement, from a pragmatic point of view, generation of such states to be sent along long distances can never be achieved perfectly. We introduce the concept of ɛ blindness for UBQC, in analogy to the concept of ɛ security developed for other cryptographic protocols, allowing us to characterize the robustness and security properties of the protocol under possible imperfections. We also present a remote blind single qubit preparation protocol with weak coherent pulses for the client to prepare, in a delegated fashion, quantum states arbitrarily close to perfect random single qubit states. This allows us to efficiently achieve ɛ-blind UBQC for any ɛ>0, even if the channel between the client and the server is arbitrarily lossy.

  12. Wavelet Coherence Analysis of Change Blindness

    Directory of Open Access Journals (Sweden)

    Irfan Ali Memon

    2013-01-01

    Full Text Available Change blindness is the incapability of the brain to detect substantial visual changes in the presence of other visual interruption. The objectives of this study are to examine the EEG (Electroencephalographic based changes in functional connectivity of the brain due to the change blindness. The functional connectivity was estimated using the wavelet-based MSC (Magnitude Square Coherence function of ERPs (Event Related Potentials. The ERPs of 30 subjects were used and were recorded using the visual attention experiment in which subjects were instructed to detect changes in visual stimulus presented before them through the computer monitor. The two-way ANOVA statistical test revealed significant increase in both gamma and theta band MSCs, and significant decrease in beta band MSC for change detection trials. These findings imply that change blindness might be associated to the lack of functional connectivity in gamma and theta bands and increase of functional connectivity in beta band. Since gamma, theta, and beta frequency bands reflect different functions of cognitive process such as maintenance, encoding, retrieval, and matching and work load of VSTM (Visual Short Term Memory, the change in functional connectivity might be correlated to these cognitive processes during change blindness.

  13. Vision after 53 years of blindness

    Czech Academy of Sciences Publication Activity Database

    Šikl, Radovan; Šimeček, Michal; Porubanová-Norquist, M.; Bezdíček, O.; Kremláček, J.; Stodůlka, P.; Fine, I.; Ostrovsky, Y.

    2013-01-01

    Roč. 4, č. 8 (2013), s. 498-507. ISSN 2041-6695 R&D Projects: GA ČR(CZ) GAP407/12/2528 Institutional support: RVO:68081740 Keywords : sight recovery * blindness * visual deprivation * object agnosia * prosopagnosia Subject RIV: AN - Psychology http://i-perception.perceptionweb.com/fulltext/i04/i0611.pdf

  14. Cognitive Development in Deaf-Blind Children.

    Science.gov (United States)

    Rittenhouse, Robert K.

    The paper reviews the literature and proposes a study on how nonlanguage deaf/blind children (ages 2 to 14) match and classify, the age at which the skills are reached, and the role of language in the process. The theories of J. Piaget and J. Bruner on the importance of language in stage development are explored. The Ss would be matched for age…

  15. Wavelet coherence analysis of change blindness

    International Nuclear Information System (INIS)

    Change blindness is the incapability of the brain to detect substantial visual changes in the presence of other visual interruption. The objectives of this study are to examine the EEG (Electroencephalographic) based changes in functional connectivity of the brain due to the change blindness. The functional connectivity was estimated using the wavelet-based MSC (Magnitude Square Coherence) function of ERPs (Event Related Potentials). The ERPs of 30 subjects were used and were recorded using the visual attention experiment in which subjects were instructed to detect changes in visual stimulus presented before them through the computer monitor. The two-way ANOVA statistical test revealed significant increase in both gamma and theta band MSCs, and significant decrease in beta band MSC for change detection trials. These findings imply that change blindness might be associated to the lack of functional connectivity in gamma and theta bands and increase of functional connectivity in beta band. Since gamma, theta, and beta frequency bands reflect different functions of cognitive process such as maintenance, encoding, retrieval, and matching and work load of VSTM (Visual Short Term Memory), the change in functional connectivity might be correlated to these cognitive processes during change blindness. (author)

  16. Perbandingan Efektivitas Ishihara Colour Blind Test dan Farnsworth Munsell Colour Blind Test di Fakuktas di Fakultas Kedokteran Gigi Universitas Sumatera Utara Tahun 2013

    OpenAIRE

    Indriati, Dwi Meutia

    2015-01-01

    Colour blindness is a disease caused by the inability of cone cells to capture a certain colour spectrum. Colour blindness is generally more contained on the male than the females with a 20:1 ratio. Colour blindness can be diagnosed with several test which Ishihar Colour Blind Test and Farnworth Munsell Colour Blind Test. The purpose of this research was to see a comparison the effectiveness between Ishihara Colour Blind Test with Farmsworth Munsell Colour Blind Test at the Faculty Dentist...

  17. Characteristics of Individuals with Congenital and Acquired Deaf-Blindness

    Science.gov (United States)

    Dalby, Dawn M.; Hirdes, John P.; Stolee, Paul; Strong, J. Graham; Poss, Jeff; Tjam, Erin Y.; Bowman, Lindsay; Ashworth, Melody

    2009-01-01

    Using a standardized assessment instrument, the authors compared 182 adults with congenital deaf-blindness and those with acquired deaf-blindness. They found that those with congenital deaf-blindness were more likely to have impairments in cognition, activities of daily living, and social interactions and were less likely to use speech for…

  18. 42 CFR 435.531 - Determinations of blindness.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Determinations of blindness. 435.531 Section 435... ISLANDS, AND AMERICAN SAMOA Categorical Requirements for Eligibility Blindness § 435.531 Determinations of blindness. (a) Except as specified in paragraph (b) of this section, in determining blindness— (1)...

  19. Restrictive partially blind signature for resource-constrained information systems

    NARCIS (Netherlands)

    Qiu, Weidong; Gong, Zheng; Liu, Bozhong; Long, Yu; Chen, Kefei

    2010-01-01

    Restrictive partially blind signature, which is designed for privacy oriented information systems, allows a user to obtain a blind signature from a signer whilst the blind message must obey some certain rules. In order to reduce storage and communication costs, several public-key cryptosystems are c

  20. What do colour-blind people really see?

    NARCIS (Netherlands)

    Hogervorst, M.A.; Alferdinck, J.W.A.M.

    2008-01-01

    Problem: colour perception of dichromats (colour-blind persons) Background: Various models have been proposed (e. g. Walraven & Alferdinck, 1997; Brettel et al. , 1997) to model reduced colour vision of colour-blind people. It is clear that colour-blind people cannot distinguish certain object colou

  1. OUR BLIND CHILDREN, GROWING AND LEARNING WITH THEM.

    Science.gov (United States)

    LOWENFELD, BERTHOLD

    WRITTEN AS AN AID TO PARENTS, THIS BOOK PRESENTS FACTS ON BLINDNESS AND PRACTICAL INFORMATION ON THE REARING OF BLIND CHILDREN FROM INFANCY THROUGH ADOLESCENCE. INFORMATION IS GIVEN ABOUT TEACHING BLIND CHILDREN SKILLS AND HABITS RELATED TO EATING, TOILET TRAINING, SLEEPING, DRESSING, WALKING, TALKING, AND PLAYING. SCHOOLING AND RELATED QUESTIONS…

  2. Risk of groundwater inrush in subterranean gypsum quarries: the case study of Moncalvo near Asti (North Italy)

    Science.gov (United States)

    Banzato, Cinzia; Fiorucci, Adriano; Gianotti, Alberto; de Waele, Jo; Vigna, Bartolomeo

    2010-05-01

    During the realisation of underground excavations in gypsum bedrock there is a possibility of intercepting large karst voids that can be completely filled with water under a considerable hydraulic pressure. The casual breaching of such voids can cause sudden and abundant water inrushes with consequences concerning safety of the excavation area and flooding of the tunnels. The presence of air-filled caves of great dimensions can also cause problems related to collapse of walls, ceilings and floors. In the subterranean quarry of Moncalvo d'Asti (Central Piedmont, Italy) in January 2005 an important inrush (60,000 m3 overnight) occurred causing damage to machinery and the flooding of several kilometres of underground tunnels. This inrush was caused by the breaching of a thin diaphragm of rock that separated the quarry from a large water-filled cave with water pressure of around 300 kPa along the front of the excavation. The rapid emptying of this void has caused a partial collapse of the roof of one of the largest cave chambers with the formation at the surface of a 20 metre wide sinkhole. To prevent similar phenomena to happen in the future a hydrogeological study concerning the entire gypsum mass was carried out. These investigations included monitoring of water levels intercepted by a series of boreholes, measurements of flow rates of water veins encountered by the excavations and chemical analysis of the different types of water coming from several points. This study has evidenced the presence of different drainage networks and the existence of a main karst circuit fed by diffused infiltration and recharge from the overlying marly-silty deposits and from adjacent minor less karstified systems in particularly fractured sectors of the gypsum. The waters coming from the main karst circuit are chemically very different from the waters deriving from deeper pathways. To be able to continue the excavation of gypsum in safe conditions the water levels were lowered for a

  3. Endecous peruassuensis n. sp. (Orthoptera: Grylloidea: Phalangopsidae) from caves of Eastern Brazil: evidence of isolation in the subterranean realm and discussion about troglomorphisms.

    Science.gov (United States)

    Bolfarini, Marcio P; Bichuette, Maria Elina

    2015-01-01

    We describe a new species of the genus Endecous Saussure (1878), recorded at the Lapa do Cipó and Olhos d'Água caves, which are located in the Itacarambi municipality, Minas Gerais state, Eastern Brazil. Another species, E. aguassay Mews, 2008 was recordedin the surroundings of the caves. The genus Endecous corresponds to the most common cricket in Brazilian hypogean environments. In general, these crickets inhabit the areas around cave entrances up to the aphotic zones of caves. The genus Endecous is the only cave cricket to present troglobiomorphosis, i.e., an apterous condition. The distribution of the new species is limited to these two caves, which suggests an endemism in this karst system similar to the distribution of other endemic animals, such as harvestmen and amblypygid arachnids. This species is the sixth troglobitic one described for Olhos d'Água cave, which sets this cave as a spot of subterranean fauna in Brazil. PMID:26624364

  4. Parentage analysis of Ansell’s mole-rat family groups indicates a high reproductive skew despite relatively relaxed ecological constraints on dispersal

    Czech Academy of Sciences Publication Activity Database

    Patzenhauerová, Hana; Šklíba, J.; Bryja, Josef; Šumbera, R.

    2013-01-01

    Roč. 22, č. 19 (2013), s. 4988-5000. ISSN 0962-1083 R&D Projects: GA AV ČR IAA601410802; GA ČR GAP506/10/0983 Institutional support: RVO:68081766 Keywords : African mole-rat * dispersal * eusociality * Fukomys * mating system * reproductive skew Subject RIV: EH - Ecology, Behaviour Impact factor: 5.840, year: 2013

  5. Metabolic responses of Glossina pallidipes (Diptera: Glossinidae) puparia exposed to oxygen and temperature variation: implications for population dynamics and subterranean life.

    Science.gov (United States)

    Basson, C Helene; Terblanche, John S

    2010-12-01

    Understanding the factors affecting insect gas exchange in subterranean environments is critical to understanding energy budgets and predicting mortality under field conditions. Here, we examine the metabolic rate (MR) responses of tsetse puparia, which remain underground for ca. 1 month in this life-stage, to varying oxygen and temperature. First, the effects of temperature and oxygen on puparial MR were investigated by ramping temperature from 15 to 35°C under 10, 21 or 40% O(2). Overall, temperature was the dominant effect on puparial MR although O(2) had small but significant impacts. Second, critical O(2) concentration (P(CRIT)) for MR of puparia was examined across a range of oxygen concentrations (0-40%). P(CRIT) was 6% O(2) which is similar to P(CRIT) in other basal arthropods but relatively high for inactive or subterranean insects. Third, we asked if puparia exposed to anoxia might experience oxygen debt, potentially indicative of anaerobic metabolism or cellular repair. Metabolic responses to anoxia were limited or insignificant, but MR was marginally elevated (∼ 15%) in anoxia-exposed (4h) puparia by 12h post-anoxia. Finally, we examined the ability of puparia to withstand water submersion, thus simulating flooding conditions frequently experienced in tropical soil habitats. Puparia were unable to survive submersion for >24h suggesting limited flooding tolerance. These novel results suggest that soil conditions experienced by puparia should not be limiting for MR, except possibly under high temperature-low O(2) conditions. Due to a large safety margin between P(CRIT) and soil oxygen levels and limited effects of oxygen on metabolism during temperature ramping experiments, we suggest that Glossina pallidipes puparia are not particularly susceptible to oxygen availability in their natural environment. However, soil flooding associated with tropical rainfall likely imposes strong selection on tsetse populations and may have had important effects for

  6. Comparison of Quality of Life and Social Skills between Students with Visual Problems (Blind and Partially Blind) and Normal Students

    OpenAIRE

    Fereshteh Kordestani; Azam Daneshfar; Davood Roustaee

    2014-01-01

    This study aimed to compare the quality of life and social skills between students who are visually impaired (blind and partially blind) and normal students. The population consisted of all students with visual problems (blind and partially blind) and normal students in secondary schools in Tehran in the academic year 2013-2014. Using a multi-stage random sampling method, 40 students were selected from each group. The SF-36s quality of life questionnaire and Foster and Inderbitzen social skil...

  7. 20 CFR 416.981 - Meaning of blindness as defined in the law.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Meaning of blindness as defined in the law... INCOME FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Blindness § 416.981 Meaning of blindness as defined in the law. We will consider you blind under the law for payment...

  8. Causes of blindness in the Republic of Srpska

    Directory of Open Access Journals (Sweden)

    Kozomara Risto

    2010-01-01

    Full Text Available Introduction. To determine the prevalence and identify potentially curable causes of blindness. Material and methods. We analyzed causes of blindness in 808 blind persons, aged from 0 to 75 years. We classified our findings in 13 categories. Results. The least number of blind persons was discovered in children aged from 0 to 15 years (2.4%, as well as in teenagers (3.4%. The number of blind persons in working population, aged from 30 to 60 was (33.1% and in older population it was (60.7%. Glaucoma was the highest cause of blindness (15.9%. Complications of myopia (14.6% took the second place. Conclusion. We think that our community needs more screening projects for glaucoma, refraction anomalies in children and diabetic retinopathy, through which the causes of blindness would be discovered and treated on time and people would be much more educated about risks and consequences of untreated eye diseases and conditions.

  9. Sociocultural theory and blind taste-tests

    Directory of Open Access Journals (Sweden)

    James Paul Gee

    2010-05-01

    Full Text Available In his entertaining 1986 book, The Real Coke, the Real Story, Thomas Oliver tells the story of the now infamous “New Coke”, a story retold in Malcolm Gladwell’s (2005 best-seller Blink. In the early 1980s, Pepsi began running commercials in which people took a sip from two glasses, not knowing which was Coke and which Pepsi. The majority preferred Pepsi. The Coca-Cola Company replicated these blind taste-tests and found the same result. Losing market share, Coke—long the dominant brand—changed its old formula and came out with “New Coke”, a soda made to a new formula, one that in a new round of blind taste-tests came out above Pepsi. But New Coke was a disaster.Consumers hated it. Coke not only returned to its old formula, but Pepsi never did overtake Coke, which remains today the dominant brand world-wide.

  10. Permanent Cortical Blindness After Bronchial Artery Embolization

    Energy Technology Data Exchange (ETDEWEB)

    Doorn, Colette S. van, E-mail: cvandoorn@gmail.com; De Boo, Diederick W., E-mail: d.w.deboo@amc.uva.nl [Academic Medical Centre, Department of Radiology (Netherlands); Weersink, Els J. M., E-mail: e.j.m.weersink@amc.uva.nl [Academic Medical Centre, Department of Pulmonology (Netherlands); Delden, Otto M. van, E-mail: o.m.vandelden@amc.uva.nl; Reekers, Jim A., E-mail: j.a.reekers@amc.uva.nl; Lienden, Krijn P. van, E-mail: k.p.vanlienden@amc.uva.nl [Academic Medical Centre, Department of Radiology (Netherlands)

    2013-12-15

    A 35-year-old female with a known medical history of cystic fibrosis was admitted to our institution for massive hemoptysis. CTA depicted a hypertrophied bronchial artery to the right upper lobe and showed signs of recent bleeding at that location. Bronchial artery embolization (BAE) was performed with gelfoam slurry, because pronounced shunting to the pulmonary artery was present. Immediately after BAE, the patient developed bilateral cortical blindness. Control angiography showed an initially not opacified anastomosis between the embolized bronchial artery and the right subclavian artery, near to the origin of the right vertebral artery. Cessation of outflow in the bronchial circulation reversed the flow through the anastomosis and allowed for spill of embolization material into the posterior circulation. Unfortunately the cortical blindness presented was permanent.

  11. Latent Images, Blind Comments on Photography

    Directory of Open Access Journals (Sweden)

    Jenny Feray

    2013-12-01

    Full Text Available Photographs, or images as the final result of a process, merely mark out the moment when the eye is helplessly limited to what it sees. Thus, what escapes the eye in the physical sense, i.e. what the eye will never see, is what occurs before the product- image, within the act itself. The latent image, the desire-image, unfolds throughout the duration of the photographic act. When the picture is ‘taken’, then the desire subsides until the next desire for another image arises. Based on the photographic experiment by Jerry Chan, member of a group of blind people, this article aims at rethinking the photographic act as the real- life experience of an impression process, leading the blind apprentice photographer to experience sightedness within his very flesh.  

  12. Blind Stereoscopy of the Coronal Magnetic Field

    CERN Document Server

    Aschwanden, Markus J; Malanushenko, Anna

    2015-01-01

    We test the feasibility of 3D coronal-loop tracing in stereoscopic EUV image pairs, with the ultimate goal of enabling efficient 3D reconstruction of the coronal magnetic field that drives flares and coronal mass ejections (CMEs). We developed an automated code designed to perform triangulation of coronal loops in pairs (or triplets) of EUV images recorded from different perspectives. The automated (or blind) stereoscopy code includes three major tasks: (i) automated pattern recognition of coronal loops in EUV images, (ii) automated pairing of corresponding loop patterns from two different aspect angles, and (iii) stereoscopic triangulation of 3D loop coordinates. We perform tests with simulated stereoscopic EUV images and quantify the accuracy of all three procedures. In addition we test the performance of the blind stereoscopy code as a function of the spacecraft-separation angle and as a function of the spatial resolution. We also test the sensitivity to magnetic non-potentiality. The automated code develo...

  13. Blind Estimation of Multiple Carrier Frequency Offsets

    CERN Document Server

    Yu, Yuanning; Poor, H Vincent; Koivunen, Visa

    2007-01-01

    Multiple carrier-frequency offsets (CFO) arise in a distributed antenna system, where data are transmitted simultaneously from multiple antennas. In such systems the received signal contains multiple CFOs due to mismatch between the local oscillators of transmitters and receiver. This results in a time-varying rotation of the data constellation, which needs to be compensated for at the receiver before symbol recovery. This paper proposes a new approach for blind CFO estimation and symbol recovery. The received base-band signal is over-sampled, and its polyphase components are used to formulate a virtual Multiple-Input Multiple-Output (MIMO) problem. By applying blind MIMO system estimation techniques, the system response is estimated and used to subsequently transform the multiple CFOs estimation problem into many independent single CFO estimation problems. Furthermore, an initial estimate of the CFO is obtained from the phase of the MIMO system response. The Cramer-Rao Lower bound is also derived, and the la...

  14. Emergence of Blind Areas in Information Spreading

    CERN Document Server

    Zhang, Zi-Ke; Han, Xiao-Pu; Liu, Chuang

    2013-01-01

    Recently, contagion-based (disease, information, etc.) spreading on social networks has been extensively studied. In this paper, other than traditional full interaction, we propose a partial interaction based spreading model, considering that the informed individuals would transmit information to only a certain fraction of their neighbors due to the transmission ability in real-world social networks. Simulation results on three representative networks (BA, ER, WS) indicate that the spreading efficiency is highly correlated with the network heterogeneity. In addition, a special phenomenon, namely \\emph{Information Blind Areas} where the network is separated by several information-unreachable clusters, will emerge from the spreading process. Furthermore, we also find that the size distribution of such information blind areas obeys power-law-like distribution, which has very similar exponent with that of site percolation. Detailed analyses show that the critical value is decreasing along with the network heterog...

  15. Multiple Blind Beamforming Based on LSCMA

    Science.gov (United States)

    Guo, Yan; Li, Ning; Lim, Myoung-Seob; Wang, Jin-Long

    Blind beamforming plays an important role in multiple-input multiple-output (MIMO) Systems, radar, cognitive radio, and system identification. In this paper, we propose a new algorithm for multiple blind beamforming algorithm based on the least square constant modulus algorithm (LSCMA). The new method consists of the following three parts: (a) beamforming of one signal with LSCMA. (b) direction-of-arrival (DOA) estimation of the remaining signals by rooting the weight vector polynomial. (c) beamforming of the remaining signals with linear constraints minimum variance (LCMV) method. After the convergence of LSCMA, one signal is captured and the arrival angles of the remaining signals can be obtained by rooting the weight vector polynomial. Therefore, beamforming can be quickly established for the remaining signals using LCMV method. Simultaneously the DOA of the signals can also be obtained. Simulation results show the performance of the presented method.

  16. Simultaneous super-resolution and blind deconvolution

    Czech Academy of Sciences Publication Activity Database

    Šroubek, Filip; Cristobal, G.; Flusser, Jan

    2008-01-01

    Roč. 124, 012048 (2008), s. 1-8. ISSN 1742-6588. [4th AIP International Conference and the 1st Congress of the IPIA. Vancouver, 25.06.2007-29.06.2007] R&D Projects: GA MŠk 1M0572; GA ČR GA202/05/0242; GA ČR(CZ) GA102/08/1593 Grant ostatní: CSIC-AS(XE) 2004CZ0009 Institutional research plan: CEZ:AV0Z10750506 Keywords : blind deconvolution * superresolution Subject RIV: JD - Computer Applications, Robotics http:// library .utia.cas.cz/separaty/2008/ZOI/sroubek-flusser-simultaneous%20super-resolution%20and%20blind%20deconvolution.pdf

  17. Autobiographic narratives of congenital blind people

    Directory of Open Access Journals (Sweden)

    Maria Elisa Caputo Ferreira

    2009-12-01

    Full Text Available The research carried out in Juiz de Fora, MG, Brazil, intended at investigating, together with men and women who suffer from congenital visual impairment, how they felt about diversity, body image, self-esteem and vanity. The investigation of autobiographical accounts was the option for this study. Initially, 20 (twenty interviews were analyzed and 6 (six autobiographical accounts, selected from the peculiarities of each single interviewee – each one containing his/her single life lessons - followed suit. The conclusion reached is that the subjects had undergone an exhausting process of acceptance of their own impairment. If, on the one hand, the blindness comes with angst, uncertainties, and many difficulties, on the other hand, these circumstances lead the blind to face the ups and downs of life with courage, determination and will to live. Surprisingly, in the study the body was not approached at a source of concern or are which should be emphasized.

  18. Permanent Cortical Blindness After Bronchial Artery Embolization

    International Nuclear Information System (INIS)

    A 35-year-old female with a known medical history of cystic fibrosis was admitted to our institution for massive hemoptysis. CTA depicted a hypertrophied bronchial artery to the right upper lobe and showed signs of recent bleeding at that location. Bronchial artery embolization (BAE) was performed with gelfoam slurry, because pronounced shunting to the pulmonary artery was present. Immediately after BAE, the patient developed bilateral cortical blindness. Control angiography showed an initially not opacified anastomosis between the embolized bronchial artery and the right subclavian artery, near to the origin of the right vertebral artery. Cessation of outflow in the bronchial circulation reversed the flow through the anastomosis and allowed for spill of embolization material into the posterior circulation. Unfortunately the cortical blindness presented was permanent

  19. Seasonality and interannual variability of CH4 fluxes from the eastern Amazon Basin inferred from atmospheric mole fraction profiles

    Science.gov (United States)

    Basso, Luana S.; Gatti, Luciana V.; Gloor, Manuel; Miller, John B.; Domingues, Lucas G.; Correia, Caio S. C.; Borges, Viviane F.

    2016-01-01

    The Amazon Basin is an important region for global CH4 emissions. It hosts the largest area of humid tropical forests, and around 20% of this area is seasonally flooded. In a warming climate it is possible that CH4 emissions from the Amazon will increase both as a result of increased temperatures and precipitation. To examine if there are indications of first signs of such changes we present here a 13 year (2000-2013) record of regularly measured vertical CH4 mole fraction profiles above the eastern Brazilian Amazon, sensitive to fluxes from the region upwind of Santarém (SAN), between SAN and the Atlantic coast. Using a simple mass balance approach, we find substantial CH4 emissions with an annual average flux of 52.8 ± 6.8 mg CH4 m-2 d-1 over an area of approximately 1 × 106 km2. Fluxes are highest in two periods of the year: in the beginning of the wet season and during the dry season. Using a CO:CH4 emission factor estimated from the profile data, we estimated a contribution of biomass burning of around 15% to the total flux in the dry season, indicating that biogenic emissions dominate the CH4 flux. This 13 year record shows that CH4 emissions upwind of SAN varied over the years, with highest emissions in 2008 (around 25% higher than in 2007), mainly during the wet season, representing 19% of the observed global increase in this year.

  20. Recognition and Release of Nalidixic Acid Using Uniformly Sized -Imprinted Nanospheres: Methacrylic Acid to Methyl Methacrylate Different Mole Ratios

    Directory of Open Access Journals (Sweden)

    Mehdi Forouzani

    2013-01-01

    Full Text Available In the presence of imprinting molecules of Nalidixic acid, uniformly sized molecularly imprinted polymers (MIPs in nanometer range were synthesized. The MIPs were successfully prepared by precipitation polymerization using methacrylic acid (MAA and methyl methacrylate (MMA as functional monomers at different mole ratios. The effect of combination of MAA-to-MMA on the morphology, binding, recognition and release behaviors of the final particles were studied. The produced polymers were characterized by differential scanning calorimetry and their morphology was precisely examined by scanning electron microscopy. We obtained very uniform imprinted nanospheres with diameter of 120- 180 nm. Among the MIP nanospheres the MIPs using combination of MAA and MMA showed nanospheres with lowest mean diameter (120 nm and the highest selectivity factor (9.7. The adsorption properties of Nalidixic acid in acetonitrile for imprinted nanospheres were evaluated by equilibrium rebinding experiments. Results from binding experiments proved that MIPs exhibit specific affinity to Nalidixic acid in contrast to control polymers and this performance was affected by pH of loading solution and. Moreover, release experiments showed the controlled release of Nalidixic acid in longtime period. The loaded Nalidixic acid was released from the imprinted nanospheres within the 140 h.

  1. Recurrent hydatidiform mole: A case report of six consecutive molar pregnancies complicated by choriocarcinoma, and review of the literature

    Directory of Open Access Journals (Sweden)

    Ahlam A Al-Ghamdi

    2011-01-01

    Full Text Available Hydatidiform mole (HM is the most common form of gestational trophoblastic neoplasia. Recurrence of HM is extremely rare. Here, we report the case of a patient with six consecutive partial HMs without normal pregnancy. A 42-year-old lady who was referred to us at King Fahad Hospital of the University, Al Khobar, initially as a case of 26-year-old with persistent trophoblastic disease after three recurrent molar pregnancies that were confirmed histologically in the referring hospital. She underwent evacuation and curettage and was followed up by serial β-human chorionic gonadotropin levels, and did not require chemotherapy. She then had three more molar pregnancies in 1995, 1996, and 2004; all molar pregnancies were evacuated by suction curettage at her base hospital, but in the last event, she complained of shortness of breath and abdominal pain. Diagnostic workup in our hospital confirmed choriocarcinoma, for which she received multiple regimen chemotherapy and was cured. Unfortunately, she lately presented with symptoms suggestive of premature menopause.

  2. Raman Scattering and t-Phase Lattice Vibration of 3% (mole fraction) Y2O3-ZrO2

    Institute of Scientific and Technical Information of China (English)

    Xinglun TANG; Xiuhua ZHENG

    2004-01-01

    The Raman spectra of 3% (mole fraction) Y2O3-ZrO2 (3Y) are obtained at different temperature from 77 K to 853 K. The results show that 260 cm-1 Eg and 460 cm-1 Eg modes on the spectra shift toward lower wave number with the increase of temperature; meanwhile, the continuity of the Half Width at Half Maximum (HWHM) and wave number (frequency) of Raman bands are broken and t-phase only partially transforms to m-phase at 523 K. Based on the experimental results, this paper discusses the t-phase lattice vibration of 3Y and presents the images of vibration displacement of six Raman-active modes for t-phase of ZrO2. The analysis indicates that there are diversities existing in the displacement of the atomic vibration of Raman-active modes because of their different symmetries at various temperature, which leads to the different change tendencies of Raman bands. Furthermore, the abrupt changes of some Raman-active modes indicating the atomic displacement are assumed to be the condensations of phonon modes in the t→m phase transition.

  3. Twin pregnancy and partial hydatidiform mole following in vitro fertilization and embryos transfer: a novel case of placental mosaicism

    Institute of Scientific and Technical Information of China (English)

    SUN Cheng-juan; ZHAO You-ping; YU Song; FAN Ling; WU Qing-qing; LI Guang-hui; ZHANG Wei-yuan

    2012-01-01

    Twin pregnancy with mosaic partial hydatidiform mole (PHM) and survival of two healthy fetuses following in vitro fertilization and embryos transfer (IVF-ET) is a rare situation and is considered a challenge for management.A 32-year-old Chinese woman conceived twin pregnancy following IVF-ET.At 22 weeks' gestation,an additional intrauterine echogenic mass with features of PHM were shown by successive ultrasound examinations.At 35 weeks'gestation,two live male infants and two placentas were delivered by caesarean section (CS).Histologic examination of the abnormal placenta confirmed mosaic PHM.Genetic study showed the abnormal placental mosaicism (expressed in molar-69XXY and normal vili-46XY),co-existing with a hypospadia new-born (46XY) in one amniotic sac.However,the other one was normal.Serial serum β-hCG levels showed a declining trend and serum 3-human chorionic gonadotropin (hCG) were undetectable at 6 months after delivery.The case demonstrated that it is possible to prolonged gestation by PHM under close surveillance during the entire pregnancy.

  4. Performance of N2O and CO analyser for high-precision measurements of atmospheric mole fractions

    Science.gov (United States)

    Stanley, Kieran; O'Doherty, Simon

    2016-04-01

    N2O and CO are two important biogenic and anthropogenic greenhouse gases. N2O has a global warming potential approximately 300 times greater than CO2 on a per-molecule basis over a 100 year time horizon and is one of the most important factors affecting stratospheric ozone depletion. CO is a key gas in tropospheric photochemistry, constraining OH concentrations in the unpolluted atmosphere and the oxidising capacity in the troposphere. Due to the importance of N2O and CO as greenhouse and ozone depleting gases, precise high-frequency measurements of the two gases are necessary to better understand atmospheric mixing ratios. A number of different methods are available to measure the two gases, mainly based on chromatographic and reduction methods. The chromatographic method used to quantify atmospheric N2O mole fractions has not yet reached the WMO compatibility goal of ± 0.1 ppb. Over the past few years, new analytical techniques based on optical spectroscopy have been developed and become commercially available, providing near-real time data to high precision. In this presentation, we will give an overview of the performance of an Off Axis-Integrated Cavity Output Spectroscopy analyser with improvements made to temperature and pressure stability by the Scripps Institute of Oceanography. Results of the continuous repeatability measurement (referred to as precision by the manufacturers), short- and long-term repeatability, drift, temperature dependence, instrument linearity and H2O sensitivity will be presented.

  5. Effect of radiolysis on leachability of plutonium and americium from 76-101 glass. [Glass containing 2 mole % plutonium

    Energy Technology Data Exchange (ETDEWEB)

    Nash, K.L.; Fried, S.; Friedman, A.M.; Susak, N.; Rickert, P.; Sullivan, J.C.; Karim, D.P.; Lam, D.J.

    1982-01-01

    One aspect of the leachability of actinide-bearing glass which has not been adequately addressed is the effect of radiolysis of the system (glass-water) on the amount of actinides liberated from the glass. In the present study, we have investigated the leaching of plutonium and americium from 76-101 glass samples (containing 2 mole % plutonium) in the presence of a one megaRad/hour gamma-radiation field. The presence of the radiation field was found to increase the leaching rate of both plutonium and americium by a factor of five. Speciation studies of the plutonium in the leachate indicate that the plutonium is present predominantly in the higher oxidation states, Pu(V) and Pu(VI) and that it is significantly associated with colloidal particles. Examination of the glass surfaces with x-ray photoemission spectroscopy, XPS, both before and after leaching was carried out; these studies showed lower surface concentrations of plutonium in the samples of glass leached in the radiation field. 1 figure, 3 tables.

  6. User-Centered Technologies for Blind Children

    OpenAIRE

    Jaime Sánchez

    2008-01-01

    The purpose of this paper is to review, summarize, and illustrate research work involving four audio-based games created within a user-centered design methodology through successive usability tasks and evaluations. These games were designed by considering the mental model of blind children and their styles of interaction to perceive and process data and information. The goal of these games was to enhance the cognitive development of spatial structures, memory, haptic perception, mathe...

  7. Blind Source Separation for Speaker Recognition Systems

    OpenAIRE

    Unverdorben, Michael; Rothbucher, Martin; Diepold, Klaus

    2014-01-01

    In this thesis, a combined blind source separation (BSS) and speaker recognition approach for teleconferences is studied. By using a microphone array, consisting of eight microphones, different methods to perform overdetermined independent vector analysis (IVA) are compared. One method is to select a subset of microphones or all available microphones to perform IVA. The second method, the so called subspace method, that utilizes a principal component analysis (PCA) for dimensionality reductio...

  8. Visual dreams in the congenitally blind?

    Science.gov (United States)

    Lopes da Silva, Fernando H.

    2003-08-01

    An EEG study of sleep in congenitally blind persons revealed a significant correlation between the visual activity reported during dreaming and the decrease of alpha strength recorded from the central and occipital regions of the scalp. This provides the first objective evidence that subjects who have never had visual experiences can have dreams with virtual images that are probably mediated by the activation of the cortical areas responsible for visual representations. PMID:12907221

  9. Blind Source Separation: the Sparsity Revolution

    OpenAIRE

    Bobin, J.; Starck, Jean-Luc; Moudden, Y.; Fadili, Jalal M.

    2008-01-01

    Over the last few years, the development of multi-channel sensors motivated interest in methods for the coherent processing of multivariate data. Some specific issues have already been addressed as testified by the wide literature on the so-called blind source separation (BSS) problem. In this context, as clearly emphasized by previous work, it is fundamental that the sources to be retrieved present some quantitatively measurable diversity. Recently, sparsity and morphological diversity have ...

  10. Making Visual Maps Accessible to the Blind

    OpenAIRE

    Buzzi, Maria Claudia; Buzzi, Marina; Leporini, Barbara; Martusciello, Loredana

    2011-01-01

    Visual maps deliver content in a simple and effective way. They can be useful for various purposes in areas such as street guidance, surrounding information, and education. However, sightless persons are unable to explore visual maps and risk being cut off from several multimedia Web applications. In this paper, starting from accessibility issues of map-based applications, we discuss possible interaction modalities and devices to use for truly achieving usage perspectives desired by blind peo...

  11. Navigation of blind and visually impaired people

    OpenAIRE

    Axer, Steffen; Belz, Jörg; Leske, Kathrin; Friedrich, Bernhard; Hesse, Tobias; Vollrath, Mark

    2015-01-01

    The mobility of the blind and visually impaired is associated with many barriers and risks. To secure crossings, signalized intersections are partially equipped with acoustic or tactile indicators. However, environmental conditions might interfere with the acoustic identification of the green time. Furthermore, information such as intersection topology, bicycle traffic or the curb structure is not accessible to visually impaired road users. Therefore, most trips are limited to trained routes....

  12. Social Sciences for the Prevention of Blindness

    OpenAIRE

    Goldschmidt, Pablo

    2015-01-01

    Organizations working for the elimination of Chlamydia-triggered blindness (trachoma) follow the WHO SAFE strategy (surgery for trichiasis, antibiotics, face washing and environmental changes) with the aim to achieve a minimum of 80% of children with clean faces in endemic communities, mass treatment covering the whole district with trachoma rates of 10% or more and surveillance plans. Trachoma recurrence that is common after implementing the SAFE strategy 3, 5 or even 7 times evidence that t...

  13. BLIND NASAL INTUBATION IN CRANIOROFACIAL TRAUMA

    Directory of Open Access Journals (Sweden)

    K.R.DavidThakaran

    2013-09-01

    Full Text Available Restricted mouth opening presents one of the greatest challenges to the anesthetist for endotracheal intubation and ventilation. Awake blind nasal intubation has been one of the finest and favored techniques for intubation in previous decades for restricted mouth opening patients. A coordinated team approach, monitoring and adequate counseling of the patient is mandatory for the airway management to carry out a safe surgical procedure

  14. Blind surveys for radio pulsars and transients

    OpenAIRE

    Lorimer, D.R.

    2010-01-01

    The main reasons for searching for pulsars are to: (i) get an accurate census of the neutron star population and its origin and evolution; (ii) connect neutron stars to other stellar populations in the Galaxy and globular clusters; (iii) study Galactic astronomy (the interstellar medium and magnetic field); (iv) find and study new interesting individual objects; (v) study pulsar phenomenology; (vi) find pulsars to add to the sensitivity of pulsar timing arrays. This review focuses on blind (i...

  15. Broadband Venetian Blind polarizer with dual vanes

    Science.gov (United States)

    Conroy, Bruce L.; Hoppe, Daniel J.; Imbriale, William A.

    1993-05-01

    During development of a Venetian Blind polarizer, high reflections and substantial pattern deformation were noted. Analysis showed that when the polarizer was illuminated slightly off axis, a degenerate mode was excited. This mode is resonant at the design center frequency, and was the cause of the problems. A design developed using dual vanes has been shown to be free of the problem. It also has greater bandwidth.

  16. Blind Source Separation Using Hessian Evaluation

    OpenAIRE

    Jyothirmayi M; Elavaar Kuzhali S; Sethu Selvi S

    2012-01-01

    This paper focuses on the blind image separation using sparse representation for natural images. The statistics of the natural image is based on one particular statistical property called sparseness, which is closely related to the super-gaussian distribution. Since natural images can have both gaussian and non gaussian distribution, the original infomax algorithm cannot be directly used for source separation as it is better suited to estimate the super-gaussian sources. Hence, we explore the...

  17. Blind recognition of punctured convolutional codes

    Institute of Scientific and Technical Information of China (English)

    LU Peizhong; LI Shen; ZOU Yan; LUO Xiangyang

    2005-01-01

    This paper presents an algorithm for blind recognition of punctured convolutional codes which is an important problem in adaptive modulation and coding. For a given finite sequence of convolutional code, the parity check matrix of the convolutional code is first computed by solving a linear system with adequate error tolerance. Then a minimal basic encoding matrix of the original convolutional code and its puncturing pattern are determined according to the known parity check matrix of the punctured convolutional code.

  18. Vision after 53 years of blindness

    Czech Academy of Sciences Publication Activity Database

    Šikl, Radovan; Šimeček, Michal; Porubanová, M.; Bezdíček, O.

    London: Pion, 2010. s. 57-57. [Thirty-third European Conference on Visual Perception. 22.08.2010-26.08.2010, Lausanne] R&D Projects: GA ČR GA406/09/2003 Institutional research plan: CEZ:AV0Z70250504 Keywords : blindness recovery * object perception * visual space perception Subject RIV: AN - Psychology http://www.perceptionweb.com/abstract.cgi?id=v100610

  19. Change blindness: eradication of gestalt strategies

    OpenAIRE

    Wilson, Steve; Goddard, Paul

    2011-01-01

    Arrays of eight, texture-defined rectangles were used as stimuli in a one-shot change blindness (CB) task where there was a 50% chance that one rectangle would change orientation between two successive presentations separated by an interval. CB was eliminated by cueing the target rectangle in the first stimulus, reduced by cueing in the interval and unaffected by cueing in the second presentation. This supports the idea that a representation was formed that persisted through the interval befo...

  20. A Completely Blind Video Integrity Oracle.

    Science.gov (United States)

    Mittal, Anish; Saad, Michele A; Bovik, Alan C

    2016-01-01

    Considerable progress has been made toward developing still picture perceptual quality analyzers that do not require any reference picture and that are not trained on human opinion scores of distorted images. However, there do not yet exist any such completely blind video quality assessment (VQA) models. Here, we attempt to bridge this gap by developing a new VQA model called the video intrinsic integrity and distortion evaluation oracle (VIIDEO). The new model does not require the use of any additional information other than the video being quality evaluated. VIIDEO embodies models of intrinsic statistical regularities that are observed in natural vidoes, which are used to quantify disturbances introduced due to distortions. An algorithm derived from the VIIDEO model is thereby able to predict the quality of distorted videos without any external knowledge about the pristine source, anticipated distortions, or human judgments of video quality. Even with such a paucity of information, we are able to show that the VIIDEO algorithm performs much better than the legacy full reference quality measure MSE on the LIVE VQA database and delivers performance comparable with a leading human judgment trained blind VQA model. We believe that the VIIDEO algorithm is a significant step toward making real-time monitoring of completely blind video quality possible. PMID:26599970

  1. Corona solar blind ultraviolet image detecting method

    Science.gov (United States)

    Yin, Li-min; Tang, Wen-qing; Zhang, Yu

    2009-07-01

    Corona is one of important reasons of electrical energy loss in the electric power. According to incomplete statistics, corona loss electrical energy has achieved two thousands and fifty millions kW.h in our nation every year. Sometimes corona also can have some disturbance to radio and communication. Therefore to discover and examine corona promptly has the extremely vital significance for conserving energy and realizing high quality communication. Ultraviolet image detecting technology is a preferred corona detection method in electric power. It may realize all-weather reliable survey to corona. The solar blind ultraviolet signal discharged by corona is quite weak. Moreover the ultraviolet image quality has been affected seriously by the detection system noise. A corona solar blind ultraviolet image processing method is proposed in this paper. Ultraviolet image has so small target, low contrast image, district characteristic and real-time demand that it is processed by multi-scale ultraviolet morphology filter technology based on mathematics morphology in this paper. Results show that the method can stretch image contrast, enhance target and weaken noise. The algorithm is easy to deal in parallel and it can be realized easily by hardware. It will be accurately demarcated when the condition of device need to be absolutely measured. The paper proposes a kind of mathematics morphology algorithm. Solar blind ultraviolet image will be further processed according to temperature and humidity in order to remove the infection of corona discharge demarcation and solve correct demarcation question when equipment condition need to be absolutely measured.

  2. The sensory construction of dreams and nightmare frequency in congenitally blind and late blind individuals

    DEFF Research Database (Denmark)

    Meaidi, Amani; Jennum, Poul; Ptito, Maurice;

    2014-01-01

    . Every morning participants filled in a questionnaire related to the sensory construction of the dream, its emotional and thematic content, and the possible occurrence of nightmares. We also assessed participants' ability of visual imagery during waking cognition, sleep quality, and depression...... and anxiety levels. RESULTS: All blind participants had fewer visual dream impressions compared to SC participants. In LB participants, duration of blindness was negatively correlated with duration, clarity, and color content of visual dream impressions. CB participants reported more auditory, tactile......, gustatory, and olfactory dream components compared to SC participants. In contrast, LB participants only reported more tactile dream impressions. Blind and SC participants did not differ with respect to emotional and thematic dream content. However, CB participants reported more aggressive interactions...

  3. Blindness and the age of enlightenment: Diderot's letter on the blind.

    Science.gov (United States)

    Margo, Curtis E; Harman, Lynn E; Smith, Don B

    2013-01-01

    Several months after anonymously publishing an essay in 1749 with the title "Letter on the Blind for the Use of Those Who Can See," the chief editor of the French Encyclopédie was arrested and taken to the prison fortress of Vincennes just east of Paris, France. The correctly assumed author, Denis Diderot, was 35 years old and had not yet left his imprint on the Age of Enlightenment. His letter, which recounted the life of Nicolas Saunderson, a blind mathematician, was intended to advance secular empiricism and disparage the religiously tinged rationalism put forward by Rene Descartes. The letter's discussion of sensory perception in men born blind dismissed the supposed primacy of visual imagery in abstract thinking. The essay did little to resolve any philosophical controversy, but it marked a turning point in Western attitudes toward visual disability. PMID:23307219

  4. Atypical Mole (Atypical Nevus)

    Science.gov (United States)

    ... melanoma). Remember the ABCDEs of melanoma lesions: A - Asymmetry: One half of the lesion does not mirror ... York: Mosby, 2003. Last Updated: 22 Dec 2008 Information for other ages: Child Teen Table of Contents: ...

  5. Long-term analysis of carbon dioxide and methane column-averaged mole fractions retrieved from SCIAMACHY

    Directory of Open Access Journals (Sweden)

    O. Schneising

    2011-03-01

    Full Text Available Carbon dioxide (CO2 and methane (CH4 are the two most important anthropogenic greenhouse gases contributing to global climate change. SCIAMACHY onboard ENVISAT (launch 2002 was the first and is now with TANSO onboard GOSAT (launch 2009 one of only two satellite instruments currently in space whose measurements are sensitive to CO2 and CH4 concentration changes in the lowest atmospheric layers where the variability due to sources and sinks is largest.

    We present long-term SCIAMACHY retrievals (2003–2009 of column-averaged dry air mole fractions of both gases (denoted XCO2 and XCH4 derived from absorption bands in the near-infrared/shortwave-infrared (NIR/SWIR spectral region focusing on large-scale features. The results are obtained using an upgraded version (v2 of the retrieval algorithm WFM-DOAS including several improvements, while simultaneously maintaining its high processing speed. The retrieved mole fractions are compared to global model simulations (CarbonTracker XCO2 and TM5 XCH4 being optimised by assimilating highly accurate surface measurements from the NOAA/ESRL network and taking the SCIAMACHY averaging kernels into account. The comparisons address seasonal variations and long-term characteristics.

    The steady increase of atmospheric carbon dioxide primarily caused by the burning of fossil fuels can be clearly observed with SCIAMACHY globally. The retrieved global annual mean XCO2 increase agrees with CarbonTracker within the error bars (1.80±0.13 ppm yr−1 compared to 1.81±0.09 ppm yr−1. The amplitude of the XCO2 seasonal cycle as retrieved by SCIAMACHY, which is 4.3±0.2 ppm for the Northern Hemisphere and 1.4±0.2 ppm for the Southern Hemisphere, is on average about 1 ppm larger than for CarbonTracker.

    An investigation of the boreal forest carbon uptake during the

  6. Comparison of nitrous oxide (N2O) analyzers for high-precision measurements of atmospheric mole fractions

    Science.gov (United States)

    Lebegue, Benjamin; Schmidt, Martina; Ramonet, Michel; Wastine, Benoit; Yver Kwok, Camille; Laurent, Olivier; Belviso, Sauveur; Guemri, Ali; Philippon, Carole; Smith, Jeremiah; Conil, Sebastien

    2016-03-01

    Over the last few decades, in situ measurements of atmospheric N2O mole fractions have been performed using gas chromatographs (GCs) equipped with electron capture detectors. This technique, however, becomes very challenging when trying to detect the small variations of N2O as the detectors are highly nonlinear and the GCs at remote stations require a considerable amount of maintenance by qualified technicians to maintain good short-term and long-term repeatability. With new robust optical spectrometers now available for N2O measurements, we aim to identify a robust and stable analyzer that can be integrated into atmospheric monitoring networks, such as the Integrated Carbon Observation System (ICOS). In this study, we present the most complete comparison of N2O analyzers, with seven analyzers that were developed and commercialized by five different companies. Each instrument was characterized during a time period of approximately 8 weeks. The test protocols included the characterization of the short-term and long-term repeatability, drift, temperature dependence, linearity and sensitivity to water vapor. During the test period, ambient air measurements were compared under field conditions at the Gif-sur-Yvette station. All of the analyzers showed a standard deviation better than 0.1 ppb for the 10 min averages. Some analyzers would benefit from improvements in temperature stability to reduce the instrument drift, which could then help in reducing the frequency of calibrations. For most instruments, the water vapor correction algorithms applied by companies are not sufficient for high-precision atmospheric measurements, which results in the need to dry the ambient air prior to analysis.

  7. Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole.

    Directory of Open Access Journals (Sweden)

    Kyu Rae Kim

    Full Text Available The pathogenetic mechanism underlying the hydropic change in complete hydatidiform moles (CHMs is poorly understood. A growing body of data suggests that pericytes play a role in vascular maturation. Since maturation of villous stromal vessels in CHMs is markedly impaired at early stages, we postulated that a defect in pericytes around stromal vessels in chorionic villi might cause vascular immaturity and subsequent hydropic change. To investigate this, we examined several markers of pericytes, namely, α-smooth muscle actin (α-SMA, platelet-derived growth factor receptor-β (PDGFR-β, and desmin, in 61 normally developing placentas and 41 CHMs with gestational ages of 4-12 weeks. The ultrastructure of villous stromal vessels was also examined. Mature blood vessels from normal placentas show patent vascular lumens and formed hematopoietic components in the villous stroma. α-SMA and PDGFR-β expression in the villous stroma gradually increased and extended from the chorionic plate to peripheral villous branches. The labeled cells formed a reticular network in the villous stroma and, after week 7, encircled villous stromal vessels. In comparison, α-SMA and PDGFR-β expression in the villous stroma and stromal vessels of CHMs was significantly lower (p<0.05. Ultrastructurally, endothelial cells in villous stromal vessels in normal placentas were consistently attached by pericytes after week 7 when the vessels formed distinct lumen, whereas the villous stromal vessels in CHMs consisted of linear chains of endothelial cells, often disclosing primitive clefts without hematopoietic cells inside, and neither pericytes nor basal lamina surrounded the endothelial cells at any gestational age studied. This suggests that pericytes recruitment around villous stromal vessels is defective in CHMs and links to the persistent vascular immaturity of the villous stroma in CHMs, which in turns leads to hydropic villi.

  8. Pigmentary Markers in Danes - Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome.

    Directory of Open Access Journals (Sweden)

    Peter Johansen

    Full Text Available To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total nevus count, and the familial atypical multiple mole and melanoma (FAMMM syndrome. We typed 32 pigmentary SNP markers and sequenced MC1R in 246 healthy individuals and 116 individuals attending periodic control for malignant melanoma development, 50 of which were diagnosed with FAMMM. It was observed that individuals with any two grouped MC1R variants (missense, NM_002386:c. 456C > A (p.TYR152*, or NM_002386:c.83_84insA (p.Asn29Glnfs*14 had significantly (p<0.001 lighter skin pigmentation of the upper-inner arm than those with none or one MC1R variant. We did not observe any significant association of the MC1R variants with constitutive pigmentation measured on the buttock area. We hypothesize that the effect of MC1R variants on arm pigmentation is primarily reflecting the inability to tan when subjected to UVR. A gender specific effect on skin pigmentation was also observed, and it was found that the skin pigmentation of females on average were darker than that of males (p<0.01. We conclude that MC1R variants are associated with quantitative skin colour in a lightly pigmented Danish population. We did not observe any association between any pigmentary marker and the FAMMM syndrome. We suggest that the genetics of FAMMM is not related to the genetics of the pigmentary pathway.

  9. Comparison of nitrous oxide (N2O) analyzers for high-precision measurements of atmospheric mole fractions

    Science.gov (United States)

    Lebegue, B.; Schmidt, M.; Ramonet, M.; Wastine, B.; Yver Kwok, C.; Laurent, O.; Belviso, S.; Guemri, A.; Philippon, C.; Smith, J.; Conil, S.; Jost, H. J.; Crosson, E. R.

    2015-10-01

    Over the last few decades, in-situ measurements of atmospheric N2O mole fractions have been performed using gas chromatographs (GCs) equipped with electron capture detectors (ECDs). When trying to meet the World Meteorological Organization's (WMO) quality goal, this technique becomes very challenging as the detectors are highly non-linear and the GCs at remote stations require a considerable amount of maintenance by qualified technicians to maintain good short-term and long-term repeatability. With more robust optical spectrometers being now available for N2O measurements, we aim to identify a robust and stable analyzer that can be integrated into atmospheric monitoring networks, such as the Integrated Carbon Observation System (ICOS). In this study, we tested seven analyzers that were developed and commercialized from five different companies and compared the results with established techniques. Each instrument was characterized during a time period of approximately eight weeks. The test protocols included the characterization of the short-term and long-term repeatability, drift, temperature dependence, linearity and sensitivity to water vapor. During the test period, ambient air measurements were compared under field conditions at the Gif-sur-Yvette station. All of the analyzers showed a standard deviation better than 0.1 ppb for the 10 min averages. Some analyzers would benefit from improvements in temperature stability to reduce the instrument drift, which could then help in reducing the frequency of calibrations. For most instruments, the water vapor correction algorithms applied by companies are not sufficient for high-precision atmospheric measurements, which results in the need to dry the ambient air prior to analysis.

  10. Impact of underlap and mole-fraction on RF performance of strained-Si/Si1-xGex/strained-Si DG MOSFETs

    Science.gov (United States)

    Dutta, Arka; Koley, Kalyan; Sarkar, Chandan K.

    2014-11-01

    In this paper, a systematic RF performance analysis of double-gate strained silicon (DGSS) nMOSFETs is presented. The analysis is focused upon impact of Germanium mole-fraction variation on RF performance of underlap engineered DGSS nMOSFET. The RF performance of the device is analysed as a function of intrinsic RF figure of merits (FOMs) including non-quasi static effects (NQS). The RF FOMs are represented by the intrinsic gate to source/drain capacitance (Cgs and Cgd) and resistance (Rgs and Rgd), the transport delay (τm), the intrinsic inductance (Lsd), the cut-off frequency (fT), and the maximum oscillation frequency (fMAX). The results of the study suggested a significant improvement in the device performance, up to 40% increase in Germanium mole fraction (χ).

  11. Effects of the InAIN growth temperature and In mole fraction on subband transport in InxAI1-xN/(AIN)/GaN/AIN heterostructures

    International Nuclear Information System (INIS)

    Subband transport properties of the two-dimensional electron gas in InxAI1-xN/(AIN)/GaN/AIN heterostructures were investigated by means of variable magnetic-field Hall measurement between 30 K and 290 K. The experimental data was analyzed by using quantitative mobility spectrum analysis technique. The 2-dimensional electron gas with 1 or 2 subbands and the 2-dimensional hole were detected with i-quantitative mobility spectrum analysis technique. Mobility of the second subband of 2DEG was found to be higher than that of the first subband. The sheet carrier density for Hall, the first and the second subband were reduced while Indium mole fraction was increasing. This behavior is a result of total bound interface sheet density. During In mole fraction was increasing, second subband mobility was decreased.The first subband and Hall mobility was decreased once InAIN growth temperature was increased

  12. A NEW EFFICIENT ID-BASED PROXY BLIND SIGNATURE SCHEME

    Institute of Scientific and Technical Information of China (English)

    Ming Yang; Wang Yumin

    2008-01-01

    In a proxy blind signature scheme, the proxy signer is allowed to generate a blind signature on behalf of the original signer. The proxy blind signature scheme is useful in several applications such as e-voting, e-payment, etc. Recently, Zheng, et al. presented an IDentity (ID)-based proxy blind signature. In this paper, a new efficient ID-based proxy blind signature scheme from bilinear pairings is proposed, which can satisfy the security properties of both the proxy signatures and the blind signature schemes. Analysis of the scheme efficiency shows that the new scheme is more efficient than Zheng, et al.'s scheme. The proposed scheme is more practical in the real world.

  13. Untraceable partially blind signature based on DLOG problem

    Institute of Scientific and Technical Information of China (English)

    HUANG Zheng(黄征); CHEN Ke-fei(陈克非); KOU Wei-dong(寇卫东)

    2004-01-01

    This paper proposes a new untraceable Partially Blind Signature scheme which is a cross between the traditional signature scheme and the blind signature scheme. In this proposed scheme, the message M that the signer signed can be divided into two parts. The first part can be known to the signer (like that in the traditional signature scheme) while the other part cannot be known to the signer (like that in the blind signature scheme). After having signed M, the signer cannot determine if he has made the signature of M except through the part that he knows. We draw ideas from Brands' "Restricted Blind Signature" to solve the Untraceable Partially Blind Signature problem. Our scheme is a probabilistic signature scheme and the security of our Untraceable Partially Blind Signature scheme relies on the difficulty of computing discrete logarithm.

  14. Enhanced chemosensory detection of negative emotions in congenital blindness

    DEFF Research Database (Denmark)

    Iversen, Katrine D.; Ptito, Maurice; Møller, Per;

    2015-01-01

    blind and normal sighted individuals in their ability to discriminate and identify emotions from body odours. A group of 14 congenitally blind and 14 age- and sex-matched sighted control subjects participated in the study. We compared participants' abilities to detect and identify by smelling sweat from...... donors who had been watching excerpts from emotional movies showing amusement, fear, disgust, or sexual arousal. Our results show that congenitally blind subjects outperformed sighted controls in identifying fear from male donors. In addition, there was a strong tendency that blind individuals were also...... better in detecting disgust. Our findings reveal that congenitally blind individuals are better at identifying ecologically important emotions and provide new insights into the mechanisms of social and affective communication in blindness....

  15. Untraceable partially blind signature based on DLOG problem.

    Science.gov (United States)

    Huang, Zheng; Chen, Ke-fei; Kou, Wei-dong

    2004-01-01

    This paper proposes a new untraceable Partially Blind Signature scheme which is a cross between the traditional signature scheme and the blind signature scheme. In this proposed scheme, the message M that the signer signed can be divided into two parts. The first part can be known to the signer (like that in the traditional signature scheme) while the other part cannot be known to the signer (like that in the blind signature scheme). After having signed M, the signer cannot determine if he has made the signature of M except through the part that he knows. We draw ideas from Brands' "Restricted Blind Signature" to solve the Untraceable Partially Blind Signature problem. Our scheme is a probabilistic signature scheme and the security of our Untraceable Partially Blind Signature scheme relies on the difficulty of computing discrete logarithm. PMID:14663850

  16. A New Proxy Blind Signature Scheme based on ECDLP

    Directory of Open Access Journals (Sweden)

    Daniyal M Alghazzawi

    2011-05-01

    Full Text Available A proxy blind signature scheme is a special form of blind signature which allows a designated person called proxy signer to sign on behalf of two or more original signers without knowing the content of the message or document. It combines the advantages of proxy signature, blind signature and multi-signature scheme and satisfies the security properties of both proxy and blind signature scheme. Most of the exiting proxy blind signature schemes were developed based on the mathematical hard problems integer factorization (IFP and simple discrete logarithm (DLP which take sub-exponential time to solve. This paper describes an secure simple proxy blind signature scheme based on Elliptic Curve Discrete Logarithm Problem (ECDLP takes fully-exponential time. This can be implemented in low power and small processor mobile devices such as smart card, PDA etc. Here also we describes implementation issues of various scalar multiplication for ECDLP.

  17. PARENT Quick Blind Round-Robin Test Report

    Energy Technology Data Exchange (ETDEWEB)

    Braatz, Brett G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Heasler, Patrick G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Meyer, Ryan M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-09-30

    The U.S. Nuclear Regulatory Commission has established the Program to Assess the Reliability of Emerging Nondestructive Techniques (PARENT) whose goal is to investigate the effectiveness of current and novel nondestructive examination procedures and techniques to find flaws in nickel-alloy welds and base materials. This is to be done by conducting a series of open and blind international round-robin tests on a set of piping components that include large-bore dissimilar metal welds, small-bore dissimilar metal welds, and bottom-mounted instrumentation penetration welds. The blind testing is being conducted in two segments, one is called Quick-Blind and the other is called Blind. The Quick-Blind testing and destructive analysis of the test blocks has been completed. This report describes the four Quick-Blind test blocks used, summarizes their destructive analysis, gives an overview of the nondestructive evaluation (NDE) techniques applied, provides an analysis inspection data, and presents the conclusions drawn.

  18. Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

    OpenAIRE

    Maja Dziegelewska; Susanne Holtze; Christiane Vole; Ulrich Wachter; Uwe Menzel; Michaela Morhart; Marco Groth; Karol Szafranski; Arne Sahm; Christoph Sponholz; Philip Dammann; Klaus Huse; Thomas Hildebrandt; Matthias Platzer

    2016-01-01

    Hydrogen sulfide (H2S) is a gaseous signalling molecule involved in many physiological and pathological processes. There is increasing evidence that H2S is implicated in aging and lifespan control in the diet-induced longevity models. However, blood sulfide concentration of naturally long-lived species is not known. Here we measured blood sulfide in the long-lived naked mole-rat and five other mammalian species considerably differing in lifespan and found a negative correlation between blood ...

  19. Tunable diode laser absorption spectroscopy-based tomography system for on-line monitoring of two-dimensional distributions of temperature and H2O mole fraction

    International Nuclear Information System (INIS)

    To monitor two-dimensional (2D) distributions of temperature and H2O mole fraction, an on-line tomography system based on tunable diode laser absorption spectroscopy (TDLAS) was developed. To the best of the authors’ knowledge, this is the first report on a multi-view TDLAS-based system for simultaneous tomographic visualization of temperature and H2O mole fraction in real time. The system consists of two distributed feedback (DFB) laser diodes, a tomographic sensor, electronic circuits, and a computer. The central frequencies of the two DFB laser diodes are at 7444.36 cm−1 (1343.3 nm) and 7185.6 cm−1 (1391.67 nm), respectively. The tomographic sensor is used to generate fan-beam illumination from five views and to produce 60 ray measurements. The electronic circuits not only provide stable temperature and precise current controlling signals for the laser diodes but also can accurately sample the transmitted laser intensities and extract integrated absorbances in real time. Finally, the integrated absorbances are transferred to the computer, in which the 2D distributions of temperature and H2O mole fraction are reconstructed by using a modified Landweber algorithm. In the experiments, the TDLAS-based tomography system was validated by using asymmetric premixed flames with fixed and time-varying equivalent ratios, respectively. The results demonstrate that the system is able to reconstruct the profiles of the 2D distributions of temperature and H2O mole fraction of the flame and effectively capture the dynamics of the combustion process, which exhibits good potential for flame monitoring and on-line combustion diagnosis

  20. Tunable diode laser absorption spectroscopy-based tomography system for on-line monitoring of two-dimensional distributions of temperature and H2O mole fraction

    Science.gov (United States)

    Xu, Lijun; Liu, Chang; Jing, Wenyang; Cao, Zhang; Xue, Xin; Lin, Yuzhen

    2016-01-01

    To monitor two-dimensional (2D) distributions of temperature and H2O mole fraction, an on-line tomography system based on tunable diode laser absorption spectroscopy (TDLAS) was developed. To the best of the authors' knowledge, this is the first report on a multi-view TDLAS-based system for simultaneous tomographic visualization of temperature and H2O mole fraction in real time. The system consists of two distributed feedback (DFB) laser diodes, a tomographic sensor, electronic circuits, and a computer. The central frequencies of the two DFB laser diodes are at 7444.36 cm-1 (1343.3 nm) and 7185.6 cm-1 (1391.67 nm), respectively. The tomographic sensor is used to generate fan-beam illumination from five views and to produce 60 ray measurements. The electronic circuits not only provide stable temperature and precise current controlling signals for the laser diodes but also can accurately sample the transmitted laser intensities and extract integrated absorbances in real time. Finally, the integrated absorbances are transferred to the computer, in which the 2D distributions of temperature and H2O mole fraction are reconstructed by using a modified Landweber algorithm. In the experiments, the TDLAS-based tomography system was validated by using asymmetric premixed flames with fixed and time-varying equivalent ratios, respectively. The results demonstrate that the system is able to reconstruct the profiles of the 2D distributions of temperature and H2O mole fraction of the flame and effectively capture the dynamics of the combustion process, which exhibits good potential for flame monitoring and on-line combustion diagnosis.